baber/WOPTO huggingface dataset:
Patent CY-1124124-T1 (CY)
Title: Νεες υβριδικες πρωτεϊνες παγιδευσης προσδετη actriib για αγωγη νοσων μυϊκης απωλειας
Inventor: HAN HQ
IPC: C07K14/00
Filed: 2021-05-14
Abstract: Η παρούσα αποκάλυψη περιγράφει νέα υβριδικά διαλυτά ActRIIB-ECD πολυπεπτίδια τα οποία διατηρούν πλήρως τη συγγένεια δέσμευσης για μυοστατίνη και ακτιβίνη Α αλλά επιδεικνύουν σημαντικά μειωμένη δέσμευση για BMPs, ειδικά ΒΜΡ-9. Οι νέες συνθέσεις που περιγράφονται στο παρόν μπορούν να χρησιμοποιηθούν για να παρασκευασθούν νέες υβριδικές πρωτεΐνες παγίδευσης προσδέτη ActRllB, οι οποίες μπορούν να χρησιμοποιηθούν για την τροποποίηση της αύξησης των μυών, των οστών, των χόνδρων, του λίπους, των ινοβλαστών, του αίματος και του νευρωνικού ιστού ώστε να αντιμετωπισθεί η μυϊκή απώλεια, η οστική απώλεια, η αναιμία, η φλεγμονή και η ίνωση κατά έναν θεραπευτικά λογικό τρόπο. Επειδή αυτοί οι νέοι αναστολείς μυοστατίνης/ακτιβίνης επόμενης γενιάς είναι ασφαλέστερα και πιο αποτελεσματικά μόρια σε σύγκριση με τους σήμερα διαθέσιμους αναστολείς μυοστατίνης, είναι χρήσιμα σε μια ευρεία ποικιλία κλινικών ενδείξεων.
Patent CY-1124192-T1 (CY)
Title: Συσκευες για την in vivo χορηγηση φαρμακων
Inventor: LEE HEEJIN
IPC: A61M31/00
Filed: 2021-06-01
Abstract: Παρέχονται συσκευές χορήγησης φαρμάκων και μέθοδοι χορήγησης φαρμάκων σε ασθενείς. Μια συσκευή (50) περιλαμβάνει μια δεξαμενή (60) που περιέχει ένα φάρμακο (58). Η δεξαμενή (60) ορίζεται από ένα τοίχωμα (64) που έχει ένα υδατοδιαπερατό τμήμα, έτσι ώστε το υδατοδιαπερατό τμήμα να επιτρέπει στο νερό να εισέρχεται στη συσκευή (50) και να έρχεται σε επαφή με το φάρμακο (58). Ένα βύσμα συγκράτησης (56) κλείνει ένα άνοιγμα της συσκευής (50) έτσι ώστε να σχηματίζονται παροδικά μικροδίαυλοι (62) μεταξύ ενός ελαστικού τμήματος (54) της συσκευής (50) και του βύσματος συγκράτησης (56), κατά την δημιουργία μιας επαρκούς πίεσης εντός της δεξαμενής (60), για την απελευθέρωση του φαρμάκου (58) από τη συσκευή (50). Περιγράφονται επίσης μέθοδοι θεραπείας ασθενών για υπερδραστηριότητα νευρογενούς εξωστήρα μυ που προκύπτουν από έναν τραυματισμό του νωτιαίου μυελού και / ή για ιδιοπαθή υπερδραστήρια ουροδόχο κύστη και ακράτεια ούρων.
Patent HR-P20090329-T1 (HR)
Title: Anionic hydrogel matrices with ph dependent modified release as drug carriers
Inventor: GIAMMONA GAETANO
IPC: A61K31/205
Filed: 2009-06-03
Abstract: Compositions with pH-dependent modified release are described, consisting of hydrogel matrices containing one or more active ingredients, in which said matrices are suitable for releasing said active ingredients in a prolonged manner in given sites of the body.
Patent HR-P20090435-T1 (HR)
Title: Membrane electrolytic reactors system with four chambers
Inventor: BOHNSTEDT RALPH
IPC: C02F1/461
Filed: 2009-08-11
Abstract: The membrane electrolytic-reactors with four chambers and the elements to regulate degassing, is designed for the production of active pH-neutral disinfectant solutions. These solutions are electrolytically activated by weak brine and are intended for disinfection of drinking water and surfaces.
Patent HR-P20110715-T1 (HR)
Title: Production of a viable, storable worm egg suspension
Inventor: WILHELM RUDOLF
IPC: A61K35/62
Filed: 2011-10-05
Abstract: Orally administrable pharmaceutical composition production involves utilizing a storable suspension of viable of surviving eggs of parasitic, non human pathogen helminths of Trichuris suis. A sufficient number develops in helminth after taking the suspension, which is applied for stimulation of regulatory human T-cells. The suspension of the helminth eggs is treated in a sulfuric acid solution having a pH value less than 2. The pH value is adjusted more than 4 and a pharmacological acceptable preservative is added. An independent claim is also included for an orally administrable pharmaceutical composition, which has a storable suspension of parasitic, non humanpathogen helminths, where a sufficient number is developed in helminth after taking the suspension.
Patent SI-1409012-T1 (SI)
Title: Methods of inducing a cytotoxic immune response and recombinant simian adenovirus compositions useful therein
Inventor: ERTL HILDEGUND C J
IPC: C12N15/00
Filed: 2002-05-13
Abstract: A method of inducing a CD8+ T-cell response against a selected molecule by delivering the molecule via a recombinant simian adenovirus is provided. Also provided are methods of inducing interferon-alpha and interferon-beta by delivering a recombinant simian adenovirus to a subject. The methods of the invention are particularly well suited for prophylaxis and treatment of infections with human immunodeficiency virus and human papilloma virus, among others, and cancer therapy.
Patent SI-1480792-T1 (SI)
Title: Universal slicer with a positioning plate
Inventor: KOVACIC PETER
IPC: B26D7/00
Filed: 2003-02-21
Abstract: A universal slicer contains a housing, a rotatably mounted revolving blade, a positioning plate which is provided with a bearing surface for a product that is to be sliced, and a mechanism regulating the width of cut by adjusting the positioning plate in relation to the revolving blade. In order to ensure that the slices are cut in a uniform manner, particularly when using universal slicers that have a simple configuration and are inexpensive to produce, the universal slicer is provided with a tensioning device, by which the positioning plate can be prestressed free from play counter to the mechanism regulating the width of cut.
Patent SI-1539114-T1 (SI)
Title: Film coating for tablets and caplets
Inventor: CADE DOMINIQUE NICOLAS
IPC: A61K9/48
Filed: 2003-07-30
Abstract: The present invention relates to novel coating compositions for application to solid dosage forms such as tablets or caplets, solid dosage forms coated with the composition, and methods of preparing said coating compositions.
Patent SI-1450104-T1 (SI)
Title: Cooking oven
Inventor: WALTHER CHRISTOPH
IPC: F24C15/00
Filed: 2003-11-06
Abstract: The cooking oven (2) includes a heatable oven chamber (6) having a loading port (8) that can be closed by an oven door (10) having outer and inner panes. Intermediate panes are positioned between the outer and inner panes such that the outer and inner cavities are formed in between. A cooling system moves a cooling air (K1) through the outer cavity, and keeps a thermally insulating air (I) in the inner cavity.
Patent SI-2210607-T1 (SI)
Title: N-?á3-fluoro-4-(?í6-(methyloxy)-7-?á(3-morpholin-4-ylpropyl)oxy?åquinolin-4-yl?çoxy)phenyl?å-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer
Inventor: BANNEN LYNNE CANNE
IPC: A61K31/47
Filed: 2004-09-24
Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
Patent SI-1671526-T1 (SI)
Title: Soil working apparatus with interlocking tines
Inventor: GEBBEKEN MARTIN
IPC: A01B33/00
Filed: 2005-11-25
Abstract: The soil cultivation machine has a frame box with several upright axles arranged with rotors transverse to the working direction. There are two tines (12) and each tine exhibits a working part (14) and a mounting element (13). The arrangement is made such that the mounting element of the tine is connected with the mounting element of the neighboring tine of the same rotor (7).
Patent SI-1924515-T1 (SI)
Title: Gripper for containers
Inventor: BURGMEIER BERTHOLD
IPC: B67C3/00
Filed: 2006-08-31
Abstract: A gripper for containers, in particular for bottles, with at least first and second gripper arms (1, 2) which are mounted such that they can pivot and are acted on in the gripping pivoting direction by magnetically interacting permanent magnets such as, permanent magnets which simultaneously repel one another and attract one another are arranged in such a way that the sum of the repelling and attracting forces which act in the gripping pivoting direction on the gripper arms is substantially constant within a predetermined gripping range (d1 to d2) of the gripper which covers different container gripping sizes.
Patent SI-1984210-T1 (SI)
Title: Method for the surface treatment of roof racks for motor vehicles and roof racks for motor vehicles
Inventor: BINDER HANS
IPC: B60R9/00
Filed: 2007-02-03
Abstract: The invention relates to method for the surface treatment of roof racks for motor vehicles, the roof racks being composed of aluminum and/or aluminum alloy. Provision is made whereby the surface is polished at least in certain areas to achieve a brilliant finish, and the polished surface is abraded at least in certain areas to achieve a satin-finish surface section. In addition, the invention relates to a corresponding roof rack.
Patent SI-2004149-T1 (SI)
Title: Pharmaceutical compositions containing leflunomid
Inventor: DR RUCHATZ DIETER
IPC: A61K9/00
Filed: 2007-04-12
Abstract: The current invention relates to leflunomid-containing pharmaceutical compositions including an organic or anorganic acid characterized by improved stability.
Patent SI-3017909-T1 (SI)
Title: Adjusting device with a printing roller of a processing machine, in particular a moulder, and processing machine, in particular moulder, with such an adjustment device
Inventor: GRAMLICH RAINER
IPC: B27C5/00
Filed: 2015-10-13
Abstract: The adjusting device for a pressure roller of a processing machine has a pivotable support arm carrying a pressure roller adjustable with the support arm from a pressure position into a resting position. The support arm is seated on a support rod that engages a clamping aperture of a pressure roller bracket. The support rod has a first section with noncircular cross section that forms a form-fit section cooperating with the clamping aperture of the pressure roller bracket by form-fit. The support rod has a second section arranged axially offset to the first section and forming a rotary section. It rests against the inner side of the clamping aperture and allows rotation of the support rod about its axis in the clamping aperture. The pressure roller can be pivoted easily into a resting position and/or transverse to the workpiece in the width direction with a constructively simple design.
Patent TR-200000576-T1 (TR)
Title: Lipozomal kapsüllenmiş taksan uygulanması için bir yöntem
Inventor: RAHMAN AQUILAR
IPC: A61K47/24
Filed: 1999-06-29
Abstract: Kanser tedavisinde terapötik olarak gelistirilmis bir yöntemin uygulanmasinda kullanilan lipozomal kapsüllenmis taksan veya bir antineoplastik türevi veya bir karisimi saglanmaktadir. Lipozomal kapsüllenmis paclitaxel, bir toksisitle olmaksizin bir hastaya, özellikle bir insan hastaya bir saatten kisa bir sürede verilebilir.
Patent TR-200003901-T1 (TR)
Title: Saç onarımı, şekil verilmesi ve düzleştirme prosesi.
Inventor: YAMASHITA YUKO
IPC: A61Q5/02
Filed: 2000-01-11
Abstract: Saç onarimi, sekil verilmesi ve düzlestirilmesi, saçin yikanmasi ve durulanmasi; saça bir alkalin baz saç düzlestirme çözeltisinin uygulanmasi; saç yapisal yapidan elastik bir duruma geçene kadar alkalin baz çözeltisinin saçta birakilmasi; saçtan alkalin baz saç düzlestirme çözeltisinin durulanmasi  ile saçtaki yapisal bakimdan elastik durumun muhafaza edilmesi; saça saç onarim çözeltisinin uygulanmasi; saçin isi altinda kompresyonu ile saça pre-oksidasyon setinin uygulanmasi; saça bir asit durulama isleminin uygulanmasi; ve saça, saçin yapisal bakimdan elastik durumunu ortadan kaldirmaya yeter süre nötürleyici bir çözeltinin uygulanmasi asamalari ile gerçeklestirilir.
Patent TR-201005126-T1 (TR)
Title: Bir bulaşık makinası
Inventor: ASKIN UFUK
IPC: A47L15/44
Filed: 2008-12-27
Abstract: Bu buluş, yıkama esnasında içi su ile dolan ve suyun tablete (T) ile temas etmesiyle oluşan çözeltinin kazana aktarılmasını sağlayan bir hazne (3) ve haznenin (3) üst tarafına, bir menteşe mekanizması yardımıyla bir eksen etrafında dönerek (pivotally) açılıp kapatılacak şekilde takılan, açıldığında içine tablet (T) yerleştirilen, kapatıldığında, tableti (T) haznenin (2) üst tarafında yatay konumda asılı olarak tutan ve haznenin (3) içinde kalan kısmı, suyun tablete (T) ulaşmasını sağlayan ızgarah veya elek formunda bir tablet tutucuya (5) sahip deterjan kutusu (2) içeren bir bulaşık makinası (1) ile ilgilidir.
Patent DE-3486050-T2 (DE)
Inventor: MAENISHI KOZOOMRON TATEISI ELE
IPC: H01H51/22
Filed: 1984-04-27
Granted: 1993-08-19
Abstract: A movable block switch mechanism which compensates for unevenness of spring force on said block comprising in combination a base (202), a movable block (221) having projections (225) and a sheet spring (235) having two recesses (236) which loosely engage two projections (225) on said movable block (221) and having two ends (237) which engage said base (202).
Patent DE-3689117-T2 (DE)
Inventor: THOMAS-LEURQUIN GENEVIEVE
IPC: A61K47/00
Filed: 1986-12-23
Granted: 1994-05-05
Abstract: The present invention relates to a composition consisting of an association of collagen with an antiseptic and/or antiinflammatory active principle, the process for its preparation and its use for the production of a pharmaceutical composition. The pharmaceutical composition according to the invention comprises collagen as the vehicle and at least one antiseptic and/or inflammatory substance as the active principle. Application to the topical treatment of periodontal complaints.
Patent DE-3781846-T2 (DE)
Inventor: RIVA ERNESTO
IPC: A23K20/195
Filed: 1987-07-17
Granted: 1993-02-11
Abstract: A novel antibiotic, A 42867, is prepared by cultivating the strain Nocardia sp. ATCC 53492, or an antibiotic A 42867-producing mutant or variant thereof, under submerged aerobic conditions in the presence of assimilable sources of carbon, nitrogen and inorganic salts. The antibiotic and its addition salts are useful in the treatment of infectious diseases and as growth promotant agents.
Patent DE-3786370-T2 (DE)
Inventor: KEEFER RICHARD M
IPC: H05B6/64
Filed: 1987-05-08
Granted: 1993-10-28
Abstract: A container which holds material for heating or cooking in a microwave oven. Cold spots in the food are reduced by generating higher order modes of microwave energy within the microwave container. This is achieved by providing a structure (26) or structures on a surface, for example the bottom (24), of the container. In the illustrated embodiment the structure is a raised structure having side walls (32), (34) and a top wall (36). Higher order modes propagate within the container as a result of boundary conditions defined by the sidewalls (14, 16, 18, 20) of the container and sidewalls (28, 30, 32, 34) of the structure (26).
Patent DE-3789299-T2 (DE)
Inventor: DENNY WILLIAM ALEXANDER
IPC: C07D311/86
Filed: 1987-12-22
Granted: 1994-08-04
Abstract: The novel class of xanthenone-4-acetic acids represented by the general formula (I) <CHEM> where R1 represents up to two of the groups lower alkyl, halogen, CF3, CN, NO2, NH2, CH2COOH, OR2, OH, NHCOR2, NHSO2R2, SR2, SO2R2, CH2CONHR2 or NHR2 (where R2 is lower alkyl optionally substituted with hydroxy, amino or methoxy functions), at any of the positions 1-8 which are available, R1 may also represent the substitution of an aza (-N=) group for one or two of the methine (-CH=) groups in the carbocyclic rings and two of R1 on any two available adjacent positions may also represent the grouping -CH=CH-CH=CH- to form an additional fused benzene ring; or a basic addition salts thereof, possess antitumour and antibacterial properties.
Patent DE-3851565-T2 (DE)
Inventor: TIKKA PANU
IPC: D21C1/04
Filed: 1988-04-15
Granted: 1995-01-26
Abstract: The invention relates to a process for the production of a hemicellulose hydrolysate and special pulp through two steps, the first step comprising the prehydrolysis of the material and the second step the dissolving of the lignin contained in the prehydrolyzed material. According to the process the lignin dissolving is carried out by means of a neutral sulphite cooking with anthraquinone or a derivative thereof as a catalyst, the pH of the cooking liquor being initially at least 10.
Patent DE-3882187-T2 (DE)
Inventor: SHETH PARESH JASWANTLAL
IPC: B32B27/12
Filed: 1988-05-11
Granted: 1993-10-14
Abstract: Composite breathable film comprising a breathable polyolefin film heat laminated to a nonwoven HDPE fabric. Preferably, the breathable film is prepared by melt embossing a highly filled polyolefin film to impose a pattern of different film thickness therein, and stretching the embossed film. The nonwoven fabric is made by cross-laminating HDPE fibers at the crossing points to form a thin open mesh fabric, and coextruding a heat seal layer thereon. The composite is made by heat laminating the breathable film to the heat seal layer of the fabric. The resulting laminate has excellent water vapor transmissibility, air resistance and strength and is particularly adapted for use as a housewrap.
Patent TR-199900488-T2 (TR)
Inventor: PARRISH GARY CHARLES
IPC: G01B7/06
Filed: 1996-09-05
Abstract: Gelistirilmis bir ölçüm cihazi, bir destek yapisina baglanmis ve dis kalinligi asindirmak suretiyle azaltilmis bir lastigin kalinligini algilayan algilayicilari indirip kaldiran bir kaldiraç silindiri ihtiva eder. Algilayicilar, bir darbeye maruz kaldiklarinda dönebilecek sekilde bir demir çubuga baglanmistir ve otomatik olarak tekrar hizaya gelirler. Algilayicilar ayni zamanda önce birinci sonra ikinci algilayici düzgün pozisyona gelecek sekilde sirali hareket eder. Algilayicilar dönebilecek bir dis lastikle temas ettiklerinde iki rulman algilayicilar hizada tutar.
Patent AT-E345824-T2 (AT)
Inventor: RAJAMAEKI VEIKKO
IPC: A61M1/00
Filed: 2000-09-29
Granted: 2006-12-15
Abstract: The invention relates to a suction bag assembly for collection of liquid fluid, the assembly comprising a collection container (1) open at its one end, a cover (4) for closing the open end of the collection container (1), a flexible suction bag (3) which is adapted insertable into the collection container (1) so as to be attached to said cover (4), a connector (2) adapted to the collection container (1) and communicating via a flow channel with a vacuum source so as to provide a vacuum between the interior surface of the collection container (1) and the exterior surface of the suction bag (3), a patient tubing connector (5) serving to provide fluid communications from the source of fluids being sucked to the interior of the suction bag (3), a conduit (7) adapted to the cover (4) for transmitting the applied vacuum to the interior of the suction bag (3), and a filter (6) adapted to the end of the conduit (7) exiting into the interior of the suction bag (3), whereby the filter serves to prevent contaminants from entering the vacuum system.
Patent DE-60010174-T2 (DE)
Inventor: GUIOT ROLAND
IPC: F23D17/00
Filed: 2000-02-24
Granted: 2005-01-13
Abstract: Burner has, next to front nose (22), wings (20) to deviate internal flux of poor fuel coming from conduit (15). Wings form, combustion chamber, whirling jets around air jets form conduits (9, 11). Burner also comprises wings (21) for axial guiding of external flux of poor fuel coming from conduit (17). Nose has hoop (23) supporting wings (20) and inclined to rotate flux from conduit (15). An Independent claim is also included for the heating method of rotating furnace.
Patent DE-60011602-T2 (DE)
Inventor: PETERI HENRI BERNARD
IPC: F24H1/20
Filed: 2000-04-18
Granted: 2005-07-07
Abstract: A hot-water appliance capable of resisting at least the pressure of the public water supply system, comprising at least one hot-water vessel with a supply conduit connectable to the public water supply system and a discharge conduit connectable to a draw-off tap, wherein the hot-water vessel further comprises a substantially cylindrical jacket wall and two end walls, characterized in that a vacuum insulated jacket (2) surrounds at least the cylindrical wall part (1a, 9) of the hot water vessel, with said vacuum insulated jacket consisting of wall(s) composed of a solid non-plastic material composition and a thickness of less than ca. 2 cm, the wall(s) enclosing a hollow vacuum space whereupon at a temperature difference between the hot water vessel and the ambient atmosphere of at least 90° C. the vacuum insulated jacket will retain an internal absolute pressure in the vacuum space of less than 10-2 millibar, corresponding to a vacuum of less than 0.0075 torr, such that the heat loss per unit area of surface area to be insulated is not more than 200 watts per square meter.
Patent DE-60012132-T2 (DE)
Inventor: MELI M
IPC: G06F11/28
Filed: 2000-08-30
Granted: 2005-08-25
Abstract: The microcomputer has an instruction memory interface that applies instructions to an instruction execution unit. In a normal state instructions are obtained from instruction memory under control of a normal program counter. In a test state a same source of an instruction is used cyclically to apply a same instruction information from a test instruction memory. Normal addressing is suppressed in the test state, so that the same instruction is executed repeatedly independent of normal program flow.
Patent DE-60017192-T2 (DE)
Inventor: AZENS ANDRIS
IPC: G02F1/155
Filed: 2000-10-04
Granted: 2005-12-08
Abstract: The present invention discloses a color-modifying method, which copmrises the provision of a metal oxide thin film (14) based on Ni and/or Cr. The method is characterized in that, when coloring the metal oxide film (14), exposing the metal oxide thin film to ozone, and when bleaching the metal oxide film, exposing the metal oxide film to UV radiation (18). A lamination process or a deposition of another thin film may follow the exposure. Preferably, exposing the metal oxide thin film (14) to ultraviolet radiation (18) in an oxygen-containing atmosphere (20) provides the ozone exposure and exposing the metal oxide thin film to ultraviolet radiation (18) in an oxygen-free atmosphere (20) provides the ultraviolet exposure.
Patent DE-60020269-T2 (DE)
Inventor: REED JOHN
IPC: A61K38/17
Filed: 2000-03-06
Granted: 2006-01-19
Abstract: The invention described herein relates to the use of human interleukin-6 antagonists, totally incapable of binding to gp 130, as specific inhibitors of the enzyme aromatase, useful for the treatment of hormone-dependent tumours, and particularly tumours of the breast.
Patent DE-60022525-T2 (DE)
Inventor: SCHOELKENS BERNWARD
IPC: A61P9/08
Filed: 2000-08-30
Granted: 2006-06-14
Abstract: Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; and a combination product containing an an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.