baber/WOPTO huggingface dataset:
Patent CA-2497656-A1 (CA)
Inventor: HICKS JAMES LESTER
IPC: C07D401/12
Filed: 2003-08-04
Abstract: L'invention concerne des composés de formule (I) ou un de leurs sels pharmaceutiquement acceptables. Dans cette formule, R?1¿, Q, R?2¿ et R?3¿ ont la signification mentionnée dans la spécification. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule (I) ou un de ses sels pharmaceutiquement acceptables, comme défini dans la spécification, conjointement avec un support, un diluant ou un excipient pharmaceutiquement acceptable. L'invention concerne également des procédés d'inhibition d'un enzyme MMP-13 chez un animal, comprenant le fait d'administrer audit animal un composé de formule (I) ou un de ses sels pharmaceutiquement acceptables. L'invention concerne en outre des méthodes de traitement de pathologies telles que les cardiopathies, la sclérose en plaques, la polyarthrite ostéo-rhumatoïde, la polyarthrite autre qu'ostéo-rhumatoïde, l'insuffisance cardiaque, l'affection intestinale inflammatoire, les déficiences cardiaques, la dégénérescence maculaire liée à l'âge, les maladies pulmonaires chroniques obstructives, l'asthme, les maladies parodontales, le psoriasis, l'athérosclérose et l'ostéoporose chez un patient. Ces traitements comprennent l'administration à un patient d'un composé de formule (I) ou d'un de ses sels pharmaceutiquement acceptables, soit seul, soit dans une composition pharmaceutique. Ladite invention concerne de plus des combinaisons comprenant un composé de formule (I) ou un de ses sels pharmaceutiquement acceptables, conjointement avec un autre constituant pharmaceutiquement actif, comme décrit dans la spécification.
Patent CA-2502633-A1 (CA)
Title: 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives
Inventor: WAELCHLI RUDOLF
IPC: C07D211/58
Filed: 2003-10-24
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein the symbols have meaning as defined, which are antagonists of CCR-1 and which find use pharmaceutically for treatment of diseases and conditions in which CCR-1 is implicated, e.g. inflammatory diseases.
Patent CA-2506877-A1 (CA)
Inventor: ZETTL BRENT
IPC: A23L33/00
Filed: 2005-05-06
Abstract: A method for the just-in-time delivery of harvested plant material and plant compounds grown in a genetically-isolated growth environment is provided. The desired crop is grown in an underground growth chamber according to a predetermined growing model in which all growing conditions are controlled. Component yield and completion time can be accurately forecast such that the harvest time of the plant material, or the completion of upstream plant extract recovery, can be accurately forecast. The use of an underground growth chamber allows for complete control over environmental factors in growth of the plant material, and also allows for the best possible protection of the growing environment against any contamination of genetic material from outside of the chamber, as well as protection of the outdoor environment against any contamination of genetic material from inside of the chamber. The method will be particularly useful in the production of plant-made pharmaceuticals, nutraceutical and natural health products.
Patent CA-2507798-A1 (CA)
Title: Sealing device
Inventor: LUNDBERG JORGEN T
IPC: F16J15/34
Filed: 2003-10-29
Abstract: A sealing device intended for sealing between an axle journal (21, 22, 23, 2 4) and a bearing housing (30, 57, 31, 58) for the axle journal (21, 22, 23, 24) . The sealing device allows that the axle journal (21, 22, 23, 24) can be angl ed in a plane in relation to the bearing housing and can also take up axial movement. The sealing device comprises a stator ring (40), which is carried by two guide pins (41), and the stator ring (40) can be angled in a plane in relation to the guide pins (41). The sealing device comprises also a sealing ring unit (47), which is intended for sealing between the stator ring (40) a nd axle journal (21, 22, 23, 24), a bellow means (56), which is intended for sealing between the bearing housing (30, 57, 31, 58) and stator ring (40), a nd at least one resilient element (48), which is intended to ensure that the stator ring (40) abuts the sealing ring unit (47). The bellows means (56) ca n be made of a material withstanding aggressive liquids.
Patent CA-2510866-A1 (CA)
Inventor: HOMBACK FRANZ PETER
IPC: B65D85/00
Filed: 2005-06-27
Abstract: A process for manufacturing a packaging material having at least two films (14) or foils (12) bonded together to a multi-layer laminate (10) via at least one adhesive layer (13) is such that the adhesive layers are of an electron-beam-curable adhesive and the laminate is radiated with electrons to cure the adhesive. The laminate is particularly suitable for manufacturing containers, in particular such for packaging foodstuffs for humans and animals. The laminate production using electron-beam-curable adhesive results in a significant reduction in throughput time and to a reduction in solvent emissions when substituting an electron-beam-curable adhesive for a solvent-based adhesive.
Patent CA-2512694-A1 (CA)
Title: Flexible lifting apparatus
Inventor: MEAD DANA G
IPC: A61B17/02
Filed: 1996-03-01
Abstract: A method of packaging a lifting apparatus for deployment through a laparoscopic incision, the method comprising the steps of: providing a lifting apparatus comprising a flat, substantially circular or elliptical body wall engaging element having a center, an outer periphery, and opposed faces, and having a flexible lifting element attached to approximately the center and extending from one of the faces; providing an elongate pouch having an open end and having on one side a central aperture and on the other side a longitudinal line of perforations; rolling the body wail engaging element from diametrically opposed points on the outer periphery towards the center, the body wall engaging element, alter rolling, being substantially cylindrical; threading the flexible lifting element into the open end of the pouch and out of the central aperture of the pouch; and inserting the rolled body wall engaging clement into the pouch.
Patent CA-2513203-A1 (CA)
Title: Optical displacement sensor
Inventor: ROSE BJARKE
IPC: G02B27/10
Filed: 2003-02-13
Abstract: The present invention relates to a compact and inexpensive optical displacement sensor that does not require accurate control of the distance to the object. A repetitive optical structure is utilized for formation of a repetitive optical signal emitted by an illuminated moving object. The repetitive optical structure is illuminated by the light source for formation of a fringe pattern (similar to Laser Doppler Anemometry), and/or, an object is illuminated by the light source and the repetitive optical structure diverts light from the illuminated object onto light sensors. A speckle pattern is formed on the object by the illumination. The speckle pattern moves with movement of the object, and speckle pattern movement is determined without a need for imaging the object onto the repetitive optical structure.  Since the speckle pattern is not imaged onto the optical member, the distance and possible distance changes between the object and the optical member substantially do not affect system performance.
Patent CA-2516544-A1 (CA)
Title: Expression of class 2 mannosidase and class iii mannosidase in lower eukaryotic cells
Inventor: GERNGROSS TILLMAN U
IPC: C12P21/00
Filed: 2004-02-20
Abstract: A method for producing human-like glycoproteins by expressing a Class 2 ±-mannosidase having a substrate specificity for Man±1,3 and Man±1,6 glycosidic linkages in a lower eukaryote is disclosed. Hydrolysis of these linkages on oligosaccharides produces substrates for further N-glycan processing in the secretory pathway.
Patent CA-2519977-A1 (CA)
Inventor: BRISCOE TERRY L
IPC: H03K17/16
Filed: 2004-04-29
Abstract: A wear assembly (10) for attaching wear members to a lip of an excavator includes a wear member, a boss (28) and a lock (60). The lip includes an inn er face, an outer face, a digging edge and a series of through-holes spaced rearward of the digging edge. The bosses (28) are each fixed to a face of th e lip at a position rearward of the through-holes. The wear members each inclu de slots to receive the boss (28) adjacent their rear ends, and openings for receiving the locks (60) at a position forward of the bosses (28). The openings are aligned with the through-holes in the lip. The lock (60) includ es a wedge (62) and spool arrangement (64).
Patent CA-2522062-A1 (CA)
Title: Methods for relative quantification of specific nucleic acid sequences
Inventor: HUBERT NATHALIE
IPC: C12Q1/68
Filed: 2003-04-11
Abstract: This invention relates generally to a method for quantifying the number of occurrences of a specific nucleic acid sequence within a nucleic acid sample in order to circumvent the shortcomings of the methods currently available and to provide reliable quantification of a specific nucleic acid sequence within a nucleic acid sample. The present invention provides a method of assessing an amount of a known target nucleic acid sequence in a sample comprising co-amplifying said target nucleic acid sequence and a known amount of a known control nucleic acid sequence to produce respective target and control amplicons, wherein said control nucleic acid sequence is different than said target nucleic acid sequence; and determining relative amounts of said respective amplicons by determining relative quantities of a primer extension reaction using each of said respective amplicons as a template.
Patent CA-2527809-A1 (CA)
Title: Isotopically labeled chemically stable reagents and process for the synthesis thereof
Inventor: POUNDS JERRY SCOT
IPC: C07B59/00
Filed: 2004-05-28
Abstract: A radioisotope labeled reagent includes a compound having the general formula (I) where a in each occurrence independently is a carbon mass number between 11 and 14 inclusive, b in each occurrence independently is a hydrogen mass number between 1 and 3 inclusive, such that a in each occurrence is not 12 simultaneously with b in each occurrence being 1; L is a leaving group R1SO2-O-, R1 -S-, 12C1H3(12C1 H2)n-S-R1C(O)O-, NC-, (R1)3P-, XMg- and Li-, where n is an integer between 0 and 3 inclusive, where X is chloro, bromo or iodine, where R1 is H, aryl, a substituent containing aryl, C1-C20 alkyl, a substituent containing C1-C20 alkyl, C2-C20 alkenyl, a substituent containing C2-C20 alkenyl, C2-C20 alkynyl, and a substitute containing C2-C20 alkynyl with the proviso that when n is 0, a is 13 and b is 2 and R1 in R1-S is not aryl.
Patent CA-2529549-A1 (CA)
Title: Composite material having the appearance of natural stone
Inventor: WALKER GERALD W
IPC: C04B26/00
Filed: 2004-01-30
Abstract: Disclosed is a composite material having the appearance of natural stone that made from a polymer and natural aggregate. The composite material also has an antimicrobial material incorporated into it that resists the proliferation of microbes on the surface of the material. A method for producing this material is also disclosed.
Patent CA-2532824-A1 (CA)
Inventor: JOHNSTON EDWARD C
IPC: E05F15/16
Filed: 2004-06-16
Abstract: A cable tensioner (20) for a sectional overhead door (D) having a motor-driven counterbalance system (30) including, a spring-loaded axle (3 1), cable drums (24) carried by the axle, cables (C) attached to and interconnecting the cable drums and the door and forming and releasing cable wraps (29) on the cable drums upon raising and lowering of the door, the cable tensioner having, a tension spring (31) adapted to be mounted on the sectional door having a first end (34) and a second end (35), the first end being adapted to engage the door and the second end being adapted to slidingly engage the cable, wherein the tension spring urges the second end to take up any slack in the cable.
Patent CA-2533300-A1 (CA)
Title: Hot gas bypass isolation
Inventor: SISHTLA VISHNU M
IPC: F25B41/04
Filed: 2004-07-22
Abstract: A bypass line assembly (17) comprising a bypass line for transporting a gas in a flow direction, a bypass valve (23) located at a position along the bypass line, and a manual throttle valve (25) located upstream from the bypass valve, the manual throttle valve comprising a throttle valve ball comprising a pressure release passage.
Patent CA-2533356-A1 (CA)
Inventor: MIDDLEMISS STEWART N
IPC: E21B10/50
Filed: 2006-01-20
Abstract: Cutting elements of this invention include an ultra hard body joined with a metallic substrate. The body includes an uppermost layer comprising a plurality of bonded ultra hard crystals and interstitial regions, and that defines a body working surface.  The uppermost layer includes an outer region that is relatively more thermally stable than a remaining portion of the uppermost layer. The body further includes an intermediate layer joined to the uppermost layer, comprising a plurality of bonded ultra hard crystals, and having a wear resistance less than that of the uppermost layer remaining region. The body may additionally include a lowermost PCD layer that is interposed between and attached to the intermediate layer and the substrate.
Patent CA-2533396-A1 (CA)
Title: 3-aryl-4-hydroxyfuranone compounds and pharmaceutical and veterinary compositions containing them
Inventor: ANDRAE PATRICK MICHAEL
IPC: C07D405/06
Filed: 2004-08-05
Abstract: The present invention provides a compound of formula (I) and the use thereof for the inhibition of bacterial cell wall biosynthesis and for the therapeutic treatment of bacterial infection or disease in a patient in need thereof. The present invention also provides the use of the formula (I) compound for the control of ecto- or endoparasites in homeothermic animals.
Patent CA-2533722-A1 (CA)
Title: Bearing structure
Inventor: WOBBEN ALOYS
IPC: B29D24/00
Filed: 2004-08-05
Abstract: The present invention concerns a bearing structure having the features of the classifying portion of claim 1. The invention further concerns a process for the production of a shaped body, in particular a rotor blade, of a fibre composite structure, comprising the following steps: - producing shells forming the outer contour of the shaped body, - producing bearing structures of fibre strands of predetermined length which are impregnated with a hardening composite material, and - transporting the bearing structure into the shells.   Therefore the object of the present invention is to develop a process of the above-defined kind in such a way that the exothermic reaction is restricted and the risk of undulations is reduced.
Patent CA-2534054-A1 (CA)
Title: Pad printer
Inventor: KLEY-BOSLER ANTON
IPC: B41F17/00
Filed: 2004-01-29
Abstract: The invention relates to a pad printer comprising a rotary table (12), at least two printing blocks (16) that are located on the rotary table (12), a respective inking device (18) that is situated on each printing block (16) and can be displaced radially between an idle position and an inking position and a respective pad (24) that can be displaced vertically between an idle position and a first and second working position. According to the invention, the pad (24) and the inking device (18) are fixed to a radially displaceable carriage (14).
Patent CA-2537135-A1 (CA)
Title: Pyrimidothiophene compounds
Inventor: FROMONT CHRISTOFE
IPC: A61K31/00
Filed: 2004-08-26
Abstract: Compounds of formula (1) are inhibitors of HSP90 activity in vitro or in vivo, and of use in the treatment of inter alia, cancer: wherein R2 is a group of formula -(Ar1)m-(Alk1)P-(Z)r-(Alk2)S-Q wherein Ar1 is an optionally substituted aryl or heteroaryl radical, Alk' and Alk 2 are optionally substituted divalent C1-C3 alkylene or C2-C3 alkenylene radicals, m, p, r and s are independently 0 or 1, Z is -0-, -S-, -(C=O)-, -(C=S)-, -S02-, -C(=O)O-, -C(=O) NR A- , -C(=S)NR A-, -S02NR A-, -NR AC(=O)_, -NR AS02- or-NR A-wherein R  A is hydrogen or C1-C6 alkyl, and Q is hydrogen or an optionally substituted carbocyclic or heterocyclic radical; R3 is hydrogen, an optional substituent, or an optionally substituted (C1-C6)alkyl, aryl or heteroaryl radical; and R4 is a carboxylic ester, carboxamide or sulfonamide group.
Patent CA-2537818-A1 (CA)
Inventor: HENSLEY KENNETH
IPC: G01N33/68
Filed: 2004-09-15
Abstract: The invention provides methods for diagnosing, treating, or evaluating inflammatory and autoimmune diseases by sampling peripheral blood, serum, plasma, tissue, cerebrospinal fluid, or other bodily fluids from a human subject having a suspected diagnosis. The sample is analyzed for the presence and amount of certain cytokines, which provides the diagnosis, prognosis or 10 evaluation of therapeutic response.
Patent CA-2539284-A1 (CA)
Inventor: RUDKIN STEVEN
IPC: H04L12/801
Filed: 2004-09-13
Abstract: A method and system to allow congestion charging signals to be generated and congestion charges to be applied on an inter-domain basis, on an aggregated basis and not on a per flow basis. Each network domain charges its neighbouring domain for any ECN marks that it forwards to them. Since a flow will collect marks as it progresses across the network the last network domain (typically an Internet service provider (ISP) located at the edge of the network domains) will levy a charge based on a higher number of marks than any of the charges levied by other domains involved in the transmission of the flow, and this higher charge can be passed on to the end user, preferably as a single aggregated charge per subscriber per accounting period. Each network domain (whether an edge ISP or other domain such as an intermediate ISP) will forward traffic to other network domains and consequently can produce a single aggregated charge per connected domain.
Patent CA-2540776-A1 (CA)
Title: Header terrain following system
Inventor: BOMLENY DUANE MICHAEL
IPC: A01D41/127
Filed: 2006-03-22
Abstract: In an agricultural combine, a header terrain following system using a floating header having a frame, a support member supporting the frame from the ground, and a suspension variably supporting the frame from a feederhouse moveably attaching at the front of the combine. A lift cylinder supports and articulates the feederhouse from the combine, and a lift valve connects the lift cylinder to a main hydraulic circuit. A position sensor adapted to sense vertical position of the frame relative to the feederhouse attaches to the floating header. A controller communicates with the lift valve and the position sensor. The controller maintains vertical position of the frame relative to the feederhouse at a nominal value by continuously reading the position sensor and commanding the lift valve to add or subtract hydraulic fluid in the lift cylinder until position reads at the nominal value.
Patent CA-2541796-A1 (CA)
Inventor: BIRDWELL TIMOTHY GALE
IPC: F21V33/00
Filed: 2006-04-05
Abstract: An illuminated doorbell pushbutton assembly includes a pushbutton assembly that uses a light source, or a plurality thereof to illuminate the pushbutton. The assembly also includes a user-adjustable rotating task light that can be used to direct light to a door lock, a dark step, or to provide a light for identifying keys. A reflector is rotated through an arc to direct light to the area desired by the user. The assembly further includes an electrical circuit that enables the assembly to be installed with electro-mechanical or electronic chimes.
Patent CA-2542976-A1 (CA)
Title: Tool for burring
Inventor: GAISER GILBERT
IPC: B23B51/00
Filed: 2004-06-28
Abstract: The invention relates to a tool for burring holes, comprising a base body rotating around a rotational axis of the tool, said base body comprising a shaft which is used for clamping. Said tool also comprises at least one spring-elastic blade support which can be displaced with respect to the base body.  The blade support comprises at least one cutting element which protrudes in a radial manner in relation to the rotational axis, said cutting element comprising at least one cutting front edge which is oriented at least partially in a transversal manner in the direction of cutting and which has improved burring qualities and increased stability with respect to prior art.  This is achieved by virtue of the fact that the cutting element (8, 30, 31) is made of hard metal.
Patent CA-2547582-A1 (CA)
Inventor: HAMILL JACK A JR
IPC: B22F1/145
Filed: 2004-10-27
Abstract: The metallurgical powder composition suspensions of the present invention include a magnetic powder having an outer oxide layer suspended in a carrier fluid. Magnetic powders include iron-based powders, such as for example, powders of iron pre-alloyed with other elements. Alloying materials include columbium, silicon, calcium, manganese, magnesium, carbon, boron, aluminum, titanium, molybdenum, chromium, copper, nickel, gold, vanadium, phosphorus, or combinations thereof Carrier fluids include silicon-based fluids and/or oils, such as hydrocarbon oils. The outer oxide layer includes alloy materials that are reacted/complexed with oxygen. Magnetic powders exhibit low rates of oxidation over a broad temperature range. Articles incorporating metallurgical powder composition suspensions include dampeners having a chamber, a piston that reciprocates in the chamber, and a source of magnetism operatively connected to the chamber. The source of magnetism, when activated, produces a magnetic field that changes the apparent viscosity of the metallurgical powder composition suspension.
Patent CA-2548500-A1 (CA)
Title: Mixed metal oxide sorbents
Inventor: VIERHEILIG ALBERT A
IPC: C01B32/40
Filed: 2004-11-22
Abstract: The present invention is directed to methods for reducing SOx, NOx, and CO  emissions from a fluid stream comprising contacting said fluid stream with a compound comprising magnesium and aluminum and having an X-ray diffraction pattern displaying at least a reflection at a two theta peak position at about 43 degrees and about 62 degrees, wherein the ratio of magnesium to aluminum in the compound is from about 1:1 to about 10:1. In one embodiment, the ratio of magnesium to aluminum in the compound is from about 1:1 to about 6:1. In one embodiment, the ratio of magnesium to aluminum in the compound is from about 1.5:1 to about 10:1. In another embodiment, the invention is directed to methods wherein the ratio of magnesium to aluminum in the compound is from about 1.5:1 to about 6:1.
Patent CA-2548631-A1 (CA)
Inventor: BECKWITH SCOTT W
IPC: B01D53/86
Filed: 2006-05-26
Abstract: A method of triggering a film containing an oxygen scavenger includes providing composition including a peroxide; and packaging the composition in a film including an oxygen scavenger; whereby the oxygen scavenger is triggered in the absence of ultraviolet light, visible light, and electron beam radiation by exposure to the peroxide or an associated enriched oxygen environment.
Patent CA-2549049-A1 (CA)
Title: Method for reporting personal status of a mobile communication device user and method therefor
Inventor: VILLAMIL CAMILO E
IPC: H04W4/029
Filed: 2004-12-14
Abstract: A mobile communication device contains event descriptor files that define certain detectable parameters indicative of the occurrence of an event. When the mobile communication device has determined that an event has occurred, the mobile communication device proceeds to send a status message to a preselected party, indicating to the preselected party that the user of the mobile communication device has experienced the event. A wide variety of events may be described and detected, such as arrival at a particular geographic location. The mobile communication device may prompt the user before sending the status message, and may further require the user to verify the user's identity by an authentication procedure.