baber/WOPTO huggingface dataset:
Patent CA-3150186-A1 (CA)
Inventor: REED SCOTT
IPC: E01H5/02
Filed: 2022-02-25
Abstract: A joint connects a first portion of a tool to a second portion of the tool.  The joint comprises a first elongated portion, a second elongated portion, and a hub. The first elongated portion is configured to couple to the first portion of the tool and includes a first joint end. The second elongated portion is configured to couple to the second portion of the tool and includes a second joint end with a plurality of cavities formed therein. The hub is positioned between the first joint end and the second joint end and is shiftable between a locked position and an unlocked position.  The hub includes a projection that is operable to extend into one of the cavities when in the locked position and shift out of the cavities when in the unlocked position.
Patent CA-3151027-A1 (CA)
Title: Uvc germicidal light for indoor applicances
Inventor: ABEHASERA BENYAMIN
IPC: A61L2/10
Filed: 2021-11-01
Abstract: A UVC germicidal light for indoor appliances includes a housing haying UVC LED light strips, a power source, an on-off switch and an LED frequency and amplitude adjustment circuit. The light includes a magnetic attachment so that the unit can be placed inside an appliance such as a washer, dryer, dishwasher, refrigerator, or the like. Multiple modes of operation, including dimming, allow the user to select the ideal conditions for the application and germicidal needs. The UVC LEDs are configured to emit light in the range of 200-280nm.
Patent CA-3151317-A1 (CA)
Title: Compositions and methods for the treatment of swi-snf mutant tumors
Inventor: GROHAR PATRICK J
IPC: A61K31/00
Filed: 2020-09-16
Abstract: The present disclosure is directed to the use of mithramycin analogs to treat cancers having mutations in the SWI/SNF (SWItch/Sucrose Non-Fermentable) pathway, such as rhabdoid cancers with mutations in SMARCB1 (BAF47, INI1, SNF5), wherein mithramycin analogs comprising EC-8042. Further disclosed are methods of treating cancer comprising treating the subject with a second cancer therapy.
Patent CA-3154378-A1 (CA)
Title: Automatic blade holder
Inventor: ERIKSSON MAGNUS
IPC: B24B1/00
Filed: 2020-09-03
Abstract: The blade holder 100 has a movable plate 126 and a fixture 154. A rotatable bolt 118 in operative engagement with a block 132 attached to the plate. A motor 114 is in operative engagement with the bolt. The motor rotates the bolt 118 to move the plate 126 towards the fixture 154 to grip a first set of blades 182 until a torque threshold value is reached. The processor determines a number of blades included in the set of blades based on the number of rotations of the bolt. A first grinding portion of a rotating abrasive belt 186 is applied against the set of blades (having width (W1)) to sharpen the set of blades. Sliding a vise 102 sideways a distance (W1) until a second grinding portion is aligned on top of the second set of blades.
Patent CA-3155017-A1 (CA)
Title: Systems and methods for designation of rem and wake states
Inventor: HILMISSON HUGI
IPC: A61B5/00
Filed: 2020-09-21
Abstract: The present disclosure provides systems and method of analyzing whether a sleep epoch is a REM sleep epoch or a wake epoch. In accordance with aspects of the present disclosure, a computer-implemented method includes accessing cardiopulmonary coupling data spanning a sleep period for a person, identifying an epoch in the sleep period corresponding to very-low frequency coupling in the cardiopulmonary coupling data, accessing high-frequency coupling data and/or low-frequency coupling data in the cardiopulmonary coupling data corresponding to the epoch, and designating the epoch as a REM sleep epoch or as a wake epoch based on the high-frequency coupling data and/or the low-frequency coupling data corresponding to the epoch, where the epoch is designated based on the cardiopulmonary coupling data without using non-cardiopulmonary coupling physiological data.
Patent CA-3155921-A1 (CA)
Title: Huntingtin (htt) irna agent compositions and methods of use thereof
Inventor: SOUNDARAPANDIAN MANGALA MEENAKSHI
IPC: C12N15/113
Filed: 2020-10-29
Abstract: The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting a Huntingtin (HTT) gene, e.g., exon 1 of an HTT gene, as well as methods of inhibiting expression of an HTT gene and methods of treating subjects having an HTT-associated disease or disorder, e.g., Huntington's disease, using such dsRNAi agents and compositions.
Patent CA-3159283-A1 (CA)
Inventor: SHAN YUEFENG
IPC: C07D491/044
Filed: 2020-11-27
Abstract: A crystalline form A of a nitrogen-containing tricyclic compound shown in formula (I), a pharmaceutical composition containing the crystalline form A, and the use of the crystalline form A or the pharmaceutical composition in the preparation of a medication for preventing, treating or relieving an FXR-mediated disease of a patient.
Patent CA-3162366-A1 (CA)
Inventor: NOVAK PETER
IPC: A61K31/223
Filed: 2019-12-20
Abstract: A method of treating type I diabetes comprising administering a therapeutically effective amount of 64Zn-enriched zinc.
Patent CA-3162539-A1 (CA)
Title: Optimisation du microbiome
Inventor: ELLINGTON JOANNA E
IPC: G16H20/10
Filed: 2020-12-19
Abstract: La présente invention concerne des compositions et des procédés pour des compositions acides destinées à être utilisées pour optimiser le microbiome génital d'un utilisateur ou de partenaires sexuels de cet utilisateur. Les compositions peuvent comprendre un oligosaccharide prébiotique, un co-facteur métallique et une huile essentielle comprenant de l'acétate de bomyle. Les compositions sont compatibles avec le microbiote génital et sont utiles, par exemple, pour hydrater, lubrifier, nettoyer et/ou diminuer une irritation ou une inflammation de la région urogénitale et/ou anogénitale d'un sujet et/ou améliorer le microbiote génital bénéfique d'un sujet. De telles compositions sont utiles avant, pendant et/ou après l'activité sexuelle et/ou de reproduction. En outre, les compositions peuvent avoir un effet minimal ou bénéfique sur les gamètes.
Patent CA-3165349-A1 (CA)
Inventor: PIERRI CARLOS ALBERTO ATHERINOS
IPC: A63B23/04
Filed: 2021-01-25
Abstract: The present patent document relates to automatic equipment for performing orthopedic and physiotherapeutic procedures for passive motion of the knee joint (patellofemoral and tibiofemoral), incorporating three motion units: knee flexion and extension motion unit; internal and external rotation motion unit of the knee; and a multidirectional patellar mobilization unit (lower-upper and medial-lateral), an external support for multidirectional patellar mobilizer and a control unit. The flexion and extension motion unit is comprised of a mechanical and electronic structure on which the leg rests during use thereof and has at least two supports for supporting the leg located in the back region of the thigh and in the back region of the leg (calf); the internal and external rotation motion unit of the knee is comprised of a structure with a support for the leg and a support for the foot region (sole region) coupled to a knee flexion and extension motion unit; and the multidirectional patellar mobilization unit is comprised of a receptacle on which a retainer and an actuating element are disposed.
Patent CA-3169885-A1 (CA)
Title: Apparatus for sampling or gripping by means of a deformable tool
Inventor: ESCOFFIER CEDRIC
IPC: B25J15/12
Filed: 2021-03-11
Abstract: The apparatus comprises a flexible sleeve (6) mounted on a rigid support (1), the sleeve being equipped with plates (7) distributed in rings around the sleeve (6). The sleeve can be retracted by means of an actuator (3) so as to bring the end face (9) of the sleeve inside the sleeve, by making a fold (14) which pivots the plates towards the inside, forming retention surfaces (17) for objects or specimens sampled, which can be held between the plates (7) or inside chambers (18).
Patent CA-3170833-A1 (CA)
Inventor: WESCHE HOLGER
IPC: A61K39/395
Filed: 2021-02-19
Abstract: Provided herein are FLT3 binding proteins, pharmaceutical compositions comprising such proteins or fragments thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such FLT3 binding proteins. Also disclosed are methods of using the disclosed FLT3 binding proteins in the prevention, and/or treatment of diseases, conditions and disorders.
Patent CA-3171663-A1 (CA)
Inventor: TAUCHEN DANIEL J
IPC: H02K5/20
Filed: 2022-08-30
Abstract: Systems are disclosed for a generator housing that includes an outer channel configured to create an outer airflow current across an outer surfaces of a stator arranged within the housing. For example, the outer airflow current is designed to flow in a direction coaxial with an axis of rotation of a rotor contained within the housing.
Patent CA-3172480-A1 (CA)
Title: Combination treatment of small-cell lung cancer
Inventor: KOSSATZ SUSANNE
IPC: A61K51/08
Filed: 2022-04-27
Abstract: A combination comprising: (i) a radiopharmaceutical comprising (a) a radionuclide, (b) a chelator, and (c) a Somatostatin receptor binding compound; and (ii) a PARP inhibitor is disclosed. That combination may be used in a method of treating a cancer or an SSTR-positive cancer, such as a neuroendocrine cancer.
Patent CA-3176141-A1 (CA)
Title: Clad 2xxx-series aerospace product
Inventor: BURGER ACHIM
IPC: B23K20/233
Filed: 2021-04-28
Abstract: Provided herein is a rolled composite aerospace product comprising a 2XXX-series core layer and an Al-Cu alloy clad layer coupled to at least one surface of the 2XXX-series core layer, wherein the Al-Cu alloy is an aluminium alloy comprising about 0.06% to 2.8% Cu, and preferably about 0.10% to 1.8% Cu. The rolled composite aerospace product is ideally suitable for structural aerospace parts. Also described herein is a method of manufacturing a rolled composite aerospace product.
Patent CA-3176948-A1 (CA)
Inventor: WEBER GERARD
IPC: E02F9/28
Filed: 2021-03-26
Abstract: The invention relates to a change system for wear parts of an excavator bucket of an earthmoving machine, comprising a carrier structure which can be fastened to or is formed on the excavator bucket and which has a projection and also an exchange part with a pocket-like cavity for releasably plugging the exchange part onto the projection of the carrier structure, wherein, to secure the exchange part on the carrier structure, there is provided at least one connection member which is connected to the carrier structure via a first connecting mechanism and to the exchange part via a second connecting mechanism physically separated from the first connecting mechanism, wherein at least one of the two connecting mechanisms is a releasable connection.
Patent CA-3178143-A1 (CA)
Inventor: DYCK DAVID
IPC: E21B17/07
Filed: 2021-02-12
Abstract: A downhole regulating device used in a downhole drill string between a drilling rig and a drill bit. The downhole regulating device has a helical coupling between the upper and lower portion to allow a relative axial and rotational movement defined by the lead of the helical coupling, between the upper and lower portions; a bi-directional biasing device that resists movement in both extension and contraction from the neutral position depending on the combination of pumping pressure, torque, axial hanging loads from drill string components below the tool and applied weight on bit. The biasing device is designed such that there is no pre-load required. A secondary one-directional element may be part of the biasing device to modify the spring rate or stroke length in contraction direction. A metal and composite laminated torsion spring is also described.
Patent CA-3181985-A1 (CA)
Title: Utilisation de molecules de liaison a cxcl13 pour favoriser la regeneration de nerf peripherique
Inventor: DIGIOVANNI SIMONE
IPC: A61P21/00
Filed: 2021-06-08
Abstract: La présente invention concerne des procédés pour favoriser la régénération axonale de neurones sensoriels et la récupération fonctionnelle de neurones suite à une lésion nerveuse périphérique chez un sujet subissant un déclin de la régénération nerveuse dépendant du vieillissement, la méthode comprenant l'administration à un sujet en ayant besoin d'une quantité efficace d'une molécule de liaison isolée qui se lie spécifiquement à CXCL13.
Patent CA-3184421-A1 (CA)
Title: Heater management
Inventor: BILAT STEPHANE
IPC: A24F40/46
Filed: 2016-03-21
Abstract: An electrically operated aerosol-generating system comprising means to detect adverse conditions, such as a dry heater or an unauthorised type of heater. The system comprises an electric heater (30) comprising at least one heating element for heating an aerosol-forming substrate, a power supply (14), and electric circuitry (16) connected to the electric heater and to the power supply and comprising a memory, the electric circuitry (16) configured to determine an adverse condition when a ratio between an initial electrical resistance (R1) of the heater (30) and a change in electrical resistance (R2-R1) from the initial resistance is greater than a maximum threshold value or is less than a minimum threshold value stored in the memory, and to limit the power supplied to the electric heater (30), or to provide an indication to a user, if there is an adverse condition. The system has the benefit of not requiring a pre-stored maximum resistance value, and so the system is able to use different heaters and to accommodate resistance variations due to manufacturina tolerances.
Patent CA-3185069-A1 (CA)
Title: Validation de procedures de melange dans un processus de decontamination
Inventor: JANSEN ESTHER
IPC: A61L2/28
Filed: 2021-07-19
Abstract: L'invention concerne un procédé de validation d'une procédure de mélange dans un processus utilisant un système désinfectant en deux parties. Le système désinfectant comprend une première partie comprenant un premier réactif dans un milieu porteur et une deuxième partie qui est miscible avec la première partie et qui comprend un deuxième réactif dans un milieu porteur, et le premier et le deuxième réactif réagissent lorsqu'ils sont mélangés pour fournir une composition désinfectante. Le procédé selon l'invention consiste : à capturer un flux vidéo d'une zone de travail dans laquelle la procédure de mélange est effectuée par un utilisateur; à analyser le flux vidéo pour identifier au moins un événement de mélange dans le flux vidéo qui correspond à une réalisation correcte de la procédure de mélange; à déterminer, en fonction de l'événement de mélange identifié ou de chaque événement de mélange identifié, si la procédure de mélange est terminée et, lorsqu'il a été déterminé que la procédure de mélange était terminée, à entraîner la fourniture d'une indication correspondante à l'utilisateur. Le procédé selon l'invention peut consister à alerter l'utilisateur sur des erreurs potentielles et/ou à consigner des données pour fournir une piste d'audit.
Patent CA-3186240-A1 (CA)
Title: Joint d'etancheite mecanique avec saillies
Inventor: LUNDSTROM MICHAEL L
IPC: B28B21/56
Filed: 2021-07-16
Abstract: L'invention concerne un joint mécanique selon lequel un joint comprend des racleurs ou des saillies, sur une surface interne du joint d'étanchéité, sur une surface externe du joint d'étanchéité, ou sur les deux surfaces interne et externe du joint d'étanchéité.
Patent CA-3186457-A1 (CA)
Inventor: FRECHETTE JOEL
IPC: H01M4/62
Filed: 2013-05-06
Abstract: There is provided a positive electrode for a lithium-ion secondary battery which comprises: a lithium-containing metal phosphate compound coated with a carbon material having at least one phase selected from a graphene phase and an amorphous phase; conductive carbon black; and a fibrous carbon mixed material. The positive electrode is prepared by a process comprising uniformly and dispersedly mixing the carbon black and lithium-containing metal phosphate compound particulates prior to blending with a dispersion of the fibrous carbon mixed material. The fibrous carbon mixed material is a mixture of first and second fibrous carbon materials having different fiber diameter and/or length. The first fibrous carbon material is mainly present on the surface of the lithium-containing metal phosphate particulates, and the second fibrous carbon material is mainly present between the lithium-containing metal phosphate compound particulates.
Patent CA-3189310-A1 (CA)
Inventor: LOVEDAY PETER
IPC: A24F40/46
Filed: 2021-08-10
Abstract: A capsule for an electronic cigarette has a first end (1) configured to engage with an electronic cigarette device and a second end (3) arranged as a mouthpiece portion (5) having a vapor outlet (6). The capsule further comprises a liquid reservoir (30), a vaporising chamber (40) with an air inlet (46) and a vapor outlet (47), a heating element (41) to vaporise liquid received from the liquid reservoir and generate a vapor in the vaporising chamber, and a flow path (60) extending between the vaporising chamber and the mouthpiece. The heating element has a planar heating surface (45) exposed to the vaporising chamber, and a capillary element with a capillary surface (43) exposed to the liquid reservoir and extending parallel to the heating surface (45). Spacers (52) are provided so that a buffer reservoir (90) is formed towards the first end (1) of the capsule and adjacent to the capillary surface.
Patent CA-3189530-A1 (CA)
Inventor: CUMELLA MATTHEW T
IPC: A61H3/06
Filed: 2021-06-11
Abstract: La présente invention concerne un système de mobilité personnelle comprenant de multiples ajustements. Le système de mobilité personnelle peut comprendre un ou plusieurs mécanismes de stabilisation élastiques. Les ajustements peuvent comprendre un système d'ajustement télescopique pour de multiples poignées, afin d'ajuster la hauteur et la position des poignées. Le système de mobilité personnelle présente des poignées sous une diversité de positions, et de différents types, pour aider un utilisateur à se déplacer depuis une position assise vers une position debout, ainsi que vers et depuis d'autres positions. Le système de mobilité personnelle comprenant des mécanismes de stabilisation élastiques stabilise le système vis-à-vis du basculement, améliorant la sécurité de l'utilisateur en réduisant l'apparition de basculements et de chutes. Les mécanismes de stabilisation élastiques peuvent être en prise avec toutes les poignées et les surfaces de préhension du système de mobilité personnelle lorsqu'un utilisateur commence à se placer, ou les mécanismes de stabilisation élastiques peuvent être en prise uniquement avec un sous-ensemble des poignées et des surfaces de préhension.
Patent CA-3202133-A1 (CA)
Title: Procede de quantification d'oligonucleotides contenant une cpg dans des formulations comprenant de l'alun
Inventor: GOHLKE MARTIN
IPC: A61K9/19
Filed: 2021-12-14
Abstract: La présente invention concerne des procédés de caractérisation de formulations comprenant des particules d'hydroxyde d'aluminium (alun), un antigène lié à l'alun, et un oligodésoxynucléotide contenant une cytidine-phospho-guanosine non méthylée (CpG ODN). En particulier, la présente invention concerne des procédés pour déterminer la concentration de Cpg ODN dans une formulation de vaccin par l'utilisation d'un essai colorimétrique pour mesurer le phosphore total.
Patent CA-3206215-A1 (CA)
Title: Curable composition
Inventor: HOWE STEPHEN ERIC
IPC: C08L33/06
Filed: 2022-01-31
Abstract: An object of the present invention is to provide a masking material having excellent peeling properties even if the drying step is reduced, preferably without the drying step. There is provided a curable composition comprising: (A1) a prepolymer represented by (Formula1): (CH2=C(R1)-CO-O-R2-O-CO-NH-R3-NH-CO)n-R4 wherein each of R1 is independently a hydrogen atom or a methyl group, each of R2 is independently an aliphatic group having 1 to 8 carbon atoms, each of R3 is independently an aromatic or aliphatic group having 1 to 30 carbon atoms and R4 is an aromatic or aliphatic group having a number average molecular weight at least 500 and having a polycarbonate backbone and/or a polyester backbone and n is an integer from 2 to 4 and (A2) a non-polymer represented by (Formula2) : (CH2=C(R5)-CO-O-R6-O-CO-NH)m-R7 wherein each of R5 is independently a hydrogen atom or a methyl group, each of R6 is independently an aliphatic group having 1 to 8 carbon atoms, R7 is independently an aromatic or aliphatic group having 1 to 30 carbon atoms and m is an integer from 2 to 4.
Patent CA-3210327-A1 (CA)
Title: Compensation de broutage de fraise en temps reel dans des fraises chirurgicales
Inventor: LAUBENTHAL MICHAEL
IPC: A61B17/00
Filed: 2022-03-01
Abstract: L'invention concerne un système de console chirurgicale configuré pour fournir un signal d'entraînement à un instrument chirurgical pour faire tourner une fraise chirurgicale. Le système de console chirurgicale peut fournir un premier signal d'entraînement à l'instrument chirurgical pour faire tourner la fraise à une vitesse souhaitée et pour déterminer un courant électrique établi par l'instrument chirurgical sur la base du signal d'entraînement. Le système de console chirurgicale peut en outre être configuré pour identifier un événement de broutage sur la base du courant électrique, et pour fournir un second signal d'entraînement à l'instrument chirurgical sur la base de l'événement de broutage identifié.
Patent CA-3211909-A1 (CA)
Title: Reseaux antagonistes generatifs quantiques a convergence prouvable
Inventor: NIU YUEZHEN
IPC: G06N10/60
Filed: 2022-03-10
Abstract: Procédés et appareil d'apprentissage d'un état quantique cible. Selon un aspect, un procédé d'apprentissage d'un réseau antagoniste génératif quantique (QGAN) pour apprendre un état quantique cible comprend le réglage itératif de paramètres du QGAN jusqu'à ce qu'une valeur d'une fonction de perte de QGAN converge, chaque itération comprenant : la réalisation d'une opération d'enchevêtrement sur une entrée de réseau discriminateur d'un réseau discriminateur dans le QGAN pour mesurer une fidélité de l'entrée de réseau discriminateur, l'entrée de réseau discriminateur comprenant l'état quantique cible et un premier état quantique délivré par un réseau générateur dans le QGAN, le premier état quantique étant proche de l'état quantique cible ; et la réalisation d'une optimisation minimax de la fonction de perte QGAN pour mettre à jour les paramètres QGAN, la fonction de perte QGAN étant dépendante de la fidélité mesurée de l'entrée de réseau discriminateur.
Patent CA-3212262-A1 (CA)
Inventor: PHAM AI QUOC
IPC: C01G49/06
Filed: 2022-03-24
Abstract: L'invention concerne des procédés et des systèmes de dissolution d'un minerai contenant du fer. Par exemple, un procédé de traitement et de dissolution d'un minerai contenant du fer comprend: la réduction thermique d'un ou de plusieurs matériaux d'oxyde de fer non magnétite dans le minerai contenant du fer pour former de la magnétite en présence d'un réducteur, de manière à former un minerai à réduction thermique; et la dissolution d'au moins une partie du minerai à réduction thermique à l'aide d'un acide pour former une solution acide de sel de fer; la solution acide de sel de fer comprenant des protons générés électrochimiquement dans une cellule électrochimique.