baber/WOPTO huggingface dataset:
Patent NZ-589848-A (NZ)
Title: Gip-based mixed agonists for treatment of metabolic disorders and obesity
Inventor: DIMARCHI RICHARD D
IPC: A61K38/00
Filed: 2009-06-16
Abstract: Provided is an analog of glucagon having GIP agonist activity, with the following modifications: (a) a large, aromatic amino acid lacking an imidazole side chain at position 1, (b) a modification selected from the group consisting of: (i) a lactam bridge between the side chains of amino acids at positions i and i+4 or between the side chains of amino acids at positions j and j+3, wherein i is 12, 13, 16, 17, 20 or 24, and wherein j is 17, and (ii) one, two, three, or all of the amino acids at positions 16, 20, 21, and 24 of the analog are an ,-disubstituted amino acid, (c) amino acid modifications at one, two or all of positions 27, 28 and 29, and (d) 1-9 further amino acid modifications, wherein the analog exhibits at least 1% activity of native GIP at the GIP receptor, wherein the EC50 of the analog at the GIP receptor is less than 50-fold different from its EC50 at the GLP-1 receptor, optionally, wherein the GIP potency of the analog is within about 15-fold of the GLP-1 potency of the analog.
Patent NZ-590369-A (NZ)
Title: Portable electrical power source for incorporation with an armored garment
Inventor: MCELROY MICHAEL
IPC: H01M50/238
Filed: 2011-01-07
Abstract: An apparatus configured to provide electrical power while incorporated in an armoured garment. The apparatus comprises: a plate (102) having a footprint that corresponds to a plate (120) of body armour; a plurality of energy storage cells (122) carried by the power plate (102); a port carried by the plate, the port being configured to output power stored in the plurality of energy storage cells (122) from the apparatus; one or more processors (128) configured to execute computer program modules (130-142), the computer program modules (130-142) comprising: a temperature module (130) configured to monitor temperature of the energy storage cells (122) such that temperature is monitored separately for separate thermal sets of one or more of the energy storage cells (122); a charge level module (132) configured to determine charge level separately for separate charge sets of one or more the energy storage cells (122); and a status module (134) configured to determine status information associated with individual ones of energy storage cells (122). The status module (134) is configured such that the status information for a given energy storage cell (122) is determined based on (i) the temperature of the thermal set of energy storage cells (122) corresponding to the given energy storage cell (122) and (ii) the charge level of the charge set of energy storage cells (122) corresponding to the given energy storage cell (122).
Patent NZ-590913-A (NZ)
Title: (2-aminomethylquinazolin-4-yl)-(4-methoxyphenyl)methylamine for treating or ameliorating neoplasm or cancer
Inventor: ANDERSON MARK B
IPC: A01N43/54
Filed: 2009-07-09
Abstract: Disclosed is the compound (2-aminomethylquinazolin-4-yl)-(4-methoxyphenyl)methylamine, salts thereof and methods for its preparation. (2-aminomethylquinazolin-4-yl)-(4-methoxyphenyl)methylamine is a cytotoxic compound and useful for treating neoplasm or cancer.
Patent NZ-593489-A (NZ)
Title: A method for the production of pellets or briquettes
Inventor: GRONN ARNE JOHANNES
IPC: C10L5/44
Filed: 2009-10-05
Abstract: 593489 Disclosed is a method for the production of pellets or briquettes from a lignin containing material, comprising the steps of: passing the lignin containing material having a moisture content less than about 30% by weight into a reactor; heating the lignin containing material to 180-235°C by injecting steam into the reactor; maintaining the material in the reactor for 1-12 minutes to release lignin; reducing the pressure in the reactor; and forming the treated material to form pellets or briquettes. Also disclosed are the lignin containing pellets of briquettes produced by the process.
Patent NZ-595633-A (NZ)
Title: Increasing pregnancy rates
Inventor: BELL ALAN RICHARD
IPC: A61K31/57
Filed: 2006-12-01
Abstract: Disclosed is a stable formulation for controlling oestrus in a subject comprising: Gonadotropin Releasing Hormone or an acceptable salt or analogue thereof; progesterone or an analogue thereof; and an acceptable carrier which is a solvent for the progesterone or analogue thereof, or for the Gonadotrophin Releasing Hormone or salt or analogue thereof, or for both. Also disclosed is a method for increasing the probability that a female non-human animal becomes pregnant following a hormone intervention programme, comprising administering to said animal a unit dose of a formulation on day 1, said formulation comprising: Gonadotrophin Releasing Hormone or an acceptable salt or analogue thereof; progesterone or an analogue thereof; and an acceptable carrier.
Patent NZ-598603-A (NZ)
Title: Pea line ex 08570956
Inventor: WEBSTER DAVID
IPC: A01H5/10
Filed: 2012-03-06
Abstract: 598603 Disclosed is a seed or plant of pea line EX 08570956, a sample of seed of said line having been deposited under ATCC Accession Number PTA-11601.
Patent NZ-600918-A (NZ)
Title: Fluid interconnection set with particle filter
Inventor: PETERS JEAN-PIERRE
IPC: A61M5/165
Filed: 2009-12-03
Abstract: Disclosed is an intravenous fluid dispensing system (3) for dispensing one or more fluids from one or more reservoirs (2) towards a dosing device (4) to allow improved medication of a patient. The fluid dispensing system comprises a reusable interconnection set (1) suited for use with multiple patients. The reusable interconnection set comprises for each reservoir a first tubing part (7) for establishing a fluid connection from the reservoir to a corresponding filling chamber (5) of a filling and injection device (6) where each filling chamber stores an amount of fluid from the corresponding reservoir; and a second tubing part (10) for establishing a fluid connection from each of the filling chambers towards the dosing device, along with a first particle filter (13) for preventing particles of a size larger than a predetermined first size from being injected into the patient. The first particle filter is located downstream of the one or more filling chambers, within the second tubing part of the reusable interconnection set downstream of the filling chambers so that the first particle filter can be reused for several patients. A disposable interconnection line is used and is intended to be renewed with each patient; the disposable interconnection line providing a fluid connection between the reusable interconnection set and the dosing device and comprising a first and a second tubing part which are releasably connectable to each other in a liquid tight manner, wherein the fluid connection between the first and the second tubing part is established by means of an one-way valve.
Patent NZ-601139-A (NZ)
Title: Synthesis and formulations of salts of isophosphoramide mustard and analogs thereof
Inventor: WALIGORA FRANK WALTER
IPC: A61K31/66
Filed: 2009-07-30
Abstract: 601139 Disclosed is a method for the preparation of a compound of formula (D) (isophosphoramide mustard, IPM) comprising treating a benzyl isophosphoramide compound of formula (C) with a reducing agent under hydrogenolysis conditions, wherein as valence and stability permit, X and Y independently represent leaving groups; and R1 is benzyl optionally substituted with one or more substituents selected from halogen, R2, OR2 and NR22 wherein R2 is selected in each occurrence from H and lower alkyl wherein the hydrogenolysis conditions comprise hydrogen gas with a pressure greater than 1 atm.
Patent NZ-603455-A (NZ)
Title: Anti-human trop-2 antibody having antitumor activity in vivo
Inventor: KANKE TORU
IPC: A61P35/00
Filed: 2011-05-17
Abstract: Disclosed is an isolated antibody against human TROP-2, which has anti-tumour activity in vivo, wherein the amino acid sequences of CDR 1 to 3 of the H chain V region of the antibody are DYNMH, YIYPYNGGTGYNQRFKS and EDYGSSPSYAMDY, respectively, and the amino acid sequences of CDR 1 to 3 of the L chain V region of the antibody are RSSQSLVHGNGNTYLH, KVSNRFS and SQTTHVPT, respectively.
Patent NZ-603712-A (NZ)
Title: Antibodies containing therapeutic tpo/epo mimetic peptides
Inventor: SPRINGHORN JEREMY P
IPC: A61K39/00
Filed: 2010-02-18
Abstract: 603712 Disclosed is a therapeutic antibody, or a therapeutically-active fragment of the antibody, wherein the antibody or fragment comprises a light chain polypeptide and a heavy chain polypeptide, comprise at least two therapeutic peptides, wherein each therapeutic peptide is a thrombopoitin (TPO) mimtec peptide wherein at least one of the therapeutic peptides is incorporated: (a) into the hinge region of the heavy chain polypeptide; (b) at the junction between the amino-terminus of the hinge region and the region of the heavy chain polypeptide that is upstream to the hinge region; (c) at the junction between the carboxy-terminus of the hinge region and the region of the heavy chain polypeptide that is downstream of the hinge region; or (d) at a location starting within fewer than 20 amino acids upstream of the amino-terminus, or fewer than 20 amino acids downstream of the carboxy-terminus, of the hinge region of the heavy chain polypeptide, and wherein the therapeutic antibody or therapeutically-active fragment thereof comprises the variable region of the heavy chain polypeptide. Further disclosed is a therapeutic antibody, or a therapeutically-active fragment of the antibody, comprising at least two therapeutic peptides, wherein the therapeutic antibody or therapeutically-active fragment thereof comprises the variable region of a heavy chain polypeptide and the variable region of a light chain polypeptide, and wherein at least one of the therapeutic peptides is incorporated: (a) into the hinge region of the heavy chain polypeptide; (b) at the junction between the amino-terminus of the hinge region and the region of the heavy chain polypeptide that is upstream to the hinge region; (c) at the junction between the carboxy-terminus of the hinge region and the region of the heavy chain polypeptide that is downstream of the hinge region; or (d) at a location starting within fewer than 20 amino acids upstream of the amino- terminus, or fewer than 20 amino acids downstream of the carboxy-terminus, of the hinge region of the heavy chain polypeptide. Further disclosed is an isolated nucleic acid encoding a polypeptide comprising the amino acid sequence depicted in SEQ ID NO:12. SEQ ID NO: 12QVQLVQSGAEVKKPGASVKVSCKASGYTFTYYAMHWVRQAPGQRPEWMGWINGGDGKTKYAQKFQGRLAITRDTSARTAYMELISLTSEDTAVYYCAKGAEMTVGSWGPGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVANPIEGPTLRQWLAARARGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK
Patent NZ-605036-A (NZ)
Title: An improved drive mechanism for a portable power tool
Inventor: GRIFFITHS PETER MURRAY
IPC: F16H21/52
Filed: 2012-12-21
Abstract: 605036 A movement transfer mechanism is disclosed for a portable power tool (1), in particular for converting rotary motion to oscillatory motion in a cow tail trimmer. The mechanism includes a movement transfer block (10), a shaft (13) linked to a driving means and a linking arm (7) linked to the working element (4). The movement transfer block (10) includes a first sliding aperture (12) for receiving an eccentric pin (15) at the head of the shaft and a second sliding aperture (11) in line with the linking arm (7). The first (12) and second (11) apertures are perpendicular to each other.
Patent NZ-608459-A (NZ)
Title: Molecular diagnostic test for cancer
Inventor: O’DONNELL JUDE
IPC: G01N33/48
Filed: 2011-09-15
Abstract: Discloses a method of predicting responsiveness of an individual to a DNA-damage therapeutic agent or diagnosing cancer associated with a DNA damage response deficiency, comprising a. measuring expression levels of at least five biomarkers in a test sample obtained previously from the individual, wherein the at least five biomarkers are selected from the group consisting of CXCL10, MX1, IDO1, IF144L, CD2, GBP5, PRAME, ITGAL, LRP4, and APOL3; b. deriving a test score that captures the combined increased expression level of the at least five biomarkers; c. providing a threshold score comprising information correlating the combined test score and responsiveness or diagnosis; d. and comparing the combined test score to the threshold score; wherein responsiveness to a DNA-damage therapeutic agent is predicted when the combined test score exceeds the threshold score.
Patent NZ-612726-A (NZ)
Title: Safety valve for an automatic dairy animal milker unit backflusher and teat dip applicator
Inventor: STUESSEL MATTHEW J
IPC: A01J7/02
Filed: 2010-09-03
Abstract: 612726 A safety valve (60) for use in a dairy backflushing and dipping system is disclosed. The safety valve is situated on or near a milker unit to seal and protect downstream dairy milk lines from teat dip and cleaning fluids that are fed through the safety valve to upstream milker unit components. All of the fluids, including dip, cleansers, water, and air pass through and are controlled by the safety valve. The valve includes a backflush piston (120) which operates with a first seal (96) to seal a backflush conduit and with a second seal (94) to seal a milk conduit.
Patent NZ-616731-A (NZ)
Title: Apparatus and method for opening and sorting envelopes
Inventor: DEWITT ROBERT
IPC: B07C3/08
Filed: 2012-04-13
Abstract: An apparatus (10) for processing mail is dislcosed. Known envelope openers typically sever an edge of each envelope and then sort all of the envelopes to a single output area. It would be desirable to sort some of the pieces so that certain pieces can be separated from the mail. For instances, envelopes that are thick may indicate mail that requires special processing. The apparatus severs an edge of each envelope (6) in a stack of mail. The apparatus includes an input bin (20) for receiving a stack of mail. A feeder (30) feeds the bottom envelope from the input bin (20) to a transport (60) that conveys the envelope along an envelope path. A cutter (70) positioned along the envelope path severs one edge of the envelopes. A detector (40, 50) detects a characteristic of the envelope and a sorter (80) sorts the envelope in response to the detected characteristic.
Patent NZ-622064-A (NZ)
Title: Hybrid power plant for improved efficiency and dynamic performance
Inventor: BOURGEAU EDWARD PETER KENNETH
IPC: H02J1/10
Filed: 2011-06-13
Abstract: Disclosed is a method of reducing variations in a power load on an AC generator (502) in a power plant. The method includes routing power between a DC energy storage device (744) and an AC load (526) coupled to the generator (502) through a DC bus (520) during a time when the power load on the generator (502) is higher than a first level supplied by the generator (502). The AC load (526) is coupled to the DC bus (520) through an AC-to-DC converter (524), and routing power between the DC energy storage device (744) and the AC load (526) comprises routing power to the AC load (526) through the AC-to-DC converter (524). The energy storage device (744) provides energy to maintain a substantially constant power output of the generator (502).
Patent NZ-626588-A (NZ)
Title: Palm activated drug delivery device
Inventor: OLSON LORIN P
IPC: A61M5/50
Filed: 2010-10-15
Abstract: A syringe device (200) for administering medication. The device comprises a multi-part housing holding a syringe. The syringe is supported by a lower housing (202) and the plunger of the syringe is carried by and upper housing (205). Movement of the upper housing (205) towards the lower housing (202) results in the medication being administered. This embodiment is directed particularly towards a locking mechanism to lock the lower and upper housings in position unless the lower guard (203) is moved relative to the lower housing, so as to expose the needle and allow movement of the upper and lower housings.
Patent NZ-629438-A (NZ)
Title: Inhalable pharmaceutical compositions
Inventor: BOSCH H WILLIAM
IPC: A61K31/46
Filed: 2013-02-28
Abstract: Disclosed herein is a method for making inhalable composite particles comprising a pharmaceutically-active agent, the method comprising: a) providing composite particles comprising a millable grinding matrix and a solid pharmaceutically-active agent, wherein the pharmaceutically-active agent has an median particle size on a volume average basis between 50 nm and 3 μm; and b) milling the composite particles in a mill without milling bodies for a time period sufficient to produce inhalable composite particles having a mass median aerodynamic diameter between 1 μm and 20 μm. Also disclosed are inhalable compositions produced by the method.
Patent NZ-629691-A (NZ)
Title: Foliar fertiliser
Inventor: HUANG LONGBIN
IPC: C05G1/00
Filed: 2012-03-05
Abstract: Disclosed herein are foliar fertiliser compositions comprising nanopartiulate fertilising compounds, wherein the nanoparticles have contact surface area to total surface area ratio of greater than 1:4 which provides maximal leaf surface contact, limited mobility and improved solubility; a net positive charge; soluble salt-forming groups; and reactive surface edges for cation exchange to release nutrient cationic ions into the water film on leaf surfaces.
Patent NZ-630469-A (NZ)
Title: Methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
Inventor: LING LEI
IPC: C12P21/02
Filed: 2013-12-26
Abstract: The disclosure relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.
Patent NZ-631037-A (NZ)
Title: Device for processing fish
Inventor: JÜRS MICHAEL
IPC: A22C25/08
Filed: 2013-07-15
Abstract: The invention relates to an L-shaped support body (10) for accommodating and conveying a fish, tail first, through a cutting unit (4). The cutting unit has a circular knife pair (6) for belly cuts. The support body (10) has a main body (12) for fastening to a continuous conveyor and a web (14) with a support edge (16) to accommodate the spine of the fish. The bearing web (14) has a groove (18) arranged at the bottom in which the circular-blade pair (6) runs. The invention further relates to a corresponding apparatus for processing fish using such support bodies.
Patent NZ-631068-A (NZ)
Title: Texture analysis of a coated surface using electrostatics calculations
Inventor: NORRIS ALISON M
IPC: G06F17/18
Filed: 2014-09-11
Abstract: Reflectance data from a target coating generated by a paint spectrophotometer is analysed to produce so called electrostatics data by treating portions of the reflectance data as electrical point charge and “solving” the electrostatic Coulomb’s Law equations. The electrostatics data is in turn compared to similarly derived electrostatics data stored in an empirical dataset. The processor generates a coating formulation that is the same as or substantially similar in appearance to the target coating on the basis of a comparison of the calculated and stored electrostatics data.
Patent NZ-706209-A (NZ)
Title: Engine fuel enhancement management system
Inventor: MATAR WILLIAM BILL
IPC: F02M25/10
Filed: 2012-08-20
Abstract: A system for managing the addition of hydrogen gas to an engine which receives a conventional fuel, wherein the supply of conventional fuel to the engine is managed by an engine control module, the system comprising: a storage means for storing the hydrogen gas; a supply line fluidly connecting the storage means to the engine; a control means having a control unit for controlling the rate of addition of the hydrogen gas from the storage means to the engine, wherein the control means is adapted to send a modified signal to the engine control module for the engine control module to supply a reduced amount of conventional fuel to the engine when the system is operating; a high pressure to low pressure regulator valve in the supply line for converting a high pressure hydrogen gas in the storage means to a lower pressure hydrogen gas, wherein the system enables a metered amount of the hydrogen gas to be delivered across a full range of manifold pressure and throttle position; and a control valve in the supply line and wherein the control unit dynamically controls the control valve to vary the rate of flow of the lower pressure hydrogen gas to the engine in response to current intake manifold pressure and throttle position of the engine.
Patent NZ-706465-A (NZ)
Title: Hinge device for doors, shutters and the like
Inventor: BACCHETTI LUCIANO
IPC: E05F3/20
Filed: 2013-10-04
Abstract: Many conventional hinge devices are bulky and do not allow a simple and quick adjustment. The present application provides a hinge device comprising a first fixed tubular half-shell including a working chamber defining a longitudinal axis, a second tubular half-shell rotatable about the axis, a rotating pivot including a passing-through actuating member having helical shape, a plunger member slidable along the axis, and a tubular bushing having a pair of guide cam slots. A pin inserted within the passing-through actuating member is provided to allow the mutual engagement of the pivot and the bushing. The latter and said second tubular half-shell are coaxially coupled in such a manner that one defines the rotation axis of the other. A first antifriction element is interposed between said pivot and said end portion of said first tubular half-shell. The combination of the above features allows easy assembly of the hinge device. Further, the arrangement of the guide cam slots of the bushing, the pivot and the pin allows to obtain a hinge device with an improved size to force ratio.
Patent NZ-707160-A (NZ)
Title: A stable aqueous composition comprising human insulin or an analogue or derivative thereof
Inventor: SAHIB MAHARAJ K
IPC: A61K47/34
Filed: 2013-05-24
Abstract: A stable aqueous insulin preparation comprising human insulin, analogues or derivatives thereof, one or more solubility enhancing agents are selected from urea, amino acids and/or surfactants optionally one or more other pharmaceutically acceptable excipient(s).
Patent NZ-713143-A (NZ)
Title: Opioid receptor ligands and methods of using and making same
Inventor: YAMASHITA DENNIS
IPC: C07D409/12
Filed: 2012-03-23
Abstract: Disclosed herein are compounds of formula I, wherein the variables are defined in the specification. These compounds can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders. In one embodiment the compound is [(4-chlorophenyl)methyl]({ 2-[4-(4-methoxyphenyl)-2,2-dimethyloxan-4-yl]ethyl} )amine.
Patent NZ-719215-A (NZ)
Title: Pharmaceutical compositions comprising antibacterial agents
Inventor: PATEL MAHESH
IPC: A61P31/04
Filed: 2014-10-22
Abstract: Pharmaceutical compositions comprising cefepime or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed.