baber/WOPTO huggingface dataset:
Patent JP-2003181060-A (JP)
Title: Pachinko machine
Inventor: SHIRAISHI HIDETOSHI
IPC: A63F7/02
Filed: 2001-12-20
Abstract: <P>PROBLEM TO BE SOLVED: To put a player in a continuous mood of expectation or interest even in the time of a game having only a significance of a consumptive game in itself.  <P>SOLUTION: The present pachinko machine is equipped with a period setting means which sets a prescribed period, a counting means which counts the number of game balls detected by a detecting means during the prescribed period set by the period setting means, a probability setting changing means which changes setting so that the probability of big hit winning in drawing of the winning be increased by the number of times set on the basis of the number of the game balls counted by the counting means, and an information means which informs the player that the game is at least in either the prescribed period or the high-probability winning drawing period.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003187178-A (JP)
Title: Business form data management system
Inventor: MORIWAKI MASASHI
IPC: G06Q10/10
Filed: 2001-12-21
Abstract: <P>PROBLEM TO BE SOLVED: To change information without requiring much labor and time when changing the information commonly printed between two or more kinds of business forms.  <P>SOLUTION: The data commonly registered in two or more business form data holders 10-1 to 10-n are registered in a shared part database 20 in conformation to identification information capable of identifying the business form data holders 10-1 to 10-n. When data to be changed are selected, and data for correction are designated, the data to be changed are retrieved in a shared part data retrieval part 40, and the data retrieved in the shared part data retrieval part 40 are changed to the designated data in a shared part data updating part 50, and registered in a shared part database 20. The data registered in a business form data holder identified by the identification information conformed to the data retrieved in the shared part data retrieval part 40 are changed to the designated data.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2002194017-A (JP)
Title: CATALYTIC COMPONENT FOR alpha-OLEFIN POLYMERIZATION
Inventor: SUGANO TOSHIHIKO
IPC: C08F4/6592
Filed: 2001-12-25
Abstract: PROBLEM TO BE SOLVED: To obtain a catalytic component, a catalyst and to provide a method for producing an α-olefin polymer using the catalyst for obtaining the α-olefin polymer with high melting point and high molecular weight at high yield. SOLUTION: The catalytic component for α-olefin polymerization is represented by formula (1) [wherein R1 is H, a 1-6C hydrocarbon group, a 1-12C Si-containing hydrocarbon group; R2 and R3 are each a divalent 3-20C saturated or unsaturated hydrocarbon group and at least one of them forms a condensed ring comprising 7-12 membered ring having an unsaturated bond derived from them; Q is a 1-20C divalent hydrocarbon group, a silylene group, a 1-20C hydrocarbon group-containing silylene group, a germirene group or a 1-20C hydrocarbon group-containing germirene group; X and Y are each H, a halogen, a 1-20C hydrocarbon group, a 1-20C oxygen-containing hydrocarbon group; M is a transition metal of the group IVB].
Patent JP-2003190260-A (JP)
Title: Sterilizer
Inventor: MATSUFUJI MASATOSHI
IPC: A61L2/18
Filed: 2001-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a sterilizer capable of sterilizing the air and all portions in a room such as a bed, a quilt, a blanket, a floor, a wall and a ceiling with mixed oxidant liquid harmless to the human body.  <P>SOLUTION: This sterilizer is formed by a body 1 and an atomizer 2. A chemical tank 3 for storing mixed oxidant liquid, a pump 4 for feeding the mixed oxidant liquid in the chemical tank 3 to the atomizer 2, a control part 5 for controlling the operation of the atomizer 2 and the pump 4, and a drain tank 6 for storing the waste liquid are provided in the body 1. The mixed oxidant liquid atomized to the air reaches the atmosphere and all portions such as a wall and a ceiling, thereby killing germs existing in the respective portions. The mixed oxidant liquid sprayed to the interior descends from the atmosphere on the bed, the quilt, the blanket and the floor. Thus, the germs adhering thereto can be killed.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003191512-A (JP)
Title: Thermal head
Inventor: MOTO YOICHI
IPC: B41J2/335
Filed: 2001-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide a highly reliable thermal head in which the fixing position of a head substrate can be prevented effectively from varying as the thermal head is used while sustaining a high print quality.  <P>SOLUTION: A head substrate 1 arranged with a large number of heating resistors 4 is mounted on a metallic heat dissipating plate 5 through a both-sided tape 6 in the thermal head wherein fluororesin sealant 7 is applied to the head substrate 1 and the heat dissipating plate 5 while surrounding the region for mounting the head substrate 1 and the both-sided tape 6 is contained in a region surrounded by the head substrate 1, the heat dissipating plate 5 and the sealant 7.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003196683-A (JP)
Title: Three-dimensional city model generating device, and three-dimensional city model generating method
Inventor: SUGANUMA YUKO
IPC: G09B29/00
Filed: 2001-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To easily generate a high-precision and simplified three-dimensional city model using road edge lines, linear data of sidewalks, and an altitude value, linear data of outer circumferences of buildings, etc., at a desired point on a road.  <P>SOLUTION: This three-dimensional city model generating device to generate a three-dimensional city model is provided with a storage part to store road data, and a road generating part comprising a road thinning processing part using the road data stored in the storage part to conduct a thinning process to a desired point among points composing the road data for generating a three-dimensional model of a road based on the road data after the thinning process.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003155484-A (JP)
Title: Fire-resistant filler
Inventor: KAWAKAMI YOSHIMITSU
IPC: A62C2/00
Filed: 2001-11-19
Abstract: PROBLEM TO BE SOLVED: To provide a novel fire-resistant filler, as a method for preventing the spread of a fire through a division-piercing section, which permits easy execution operation and exhibits excellent preventing effects on the spread of a fire in case that the fire breaks out. SOLUTION: This fire-resistant filler is obtained by impregnating a foam with an alkali metal silicate and is filled and worked for preventing the spread of a fire through a division-piercing section. The fire-resistant filler permits easy execution operation and, in case of a fire, the alkali metal silicate functions as an endothermic fire-resistant material and is transformed, by an expansion action of residual cells in the foam, into a foam glass to block a piercing section thereby exhibiting excellent preventing effects on the spread of a fire.
Patent JP-2003201692-A (JP)
Title: Nonwoven fabric, method for producing the nonwoven fabric, and equipment for producing the same
Inventor: SHIRAISHI MATSUTARO
IPC: D04H1/732
Filed: 2001-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a nonwoven fabric, and to provide a method for producing the nonwoven fabric, capable of producing the nonwoven fabric of high quality, even when a wet process is adopted and such long fibers having a length of about 15-50 mm are used in the process.  <P>SOLUTION: This nonwoven fabric is produced by feeding the long fibers having the length of 15-50 mm into water positioned immediately before a sheet layer-forming unit at an approximately constant rate of a fed amount per unit time, making the fibers stay therein for a specified time, and filtering and collecting the fibers with wires of the sheet layer-forming unit.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003191595-A (JP)
Title: Ink jet image forming method
Inventor: IBARAKI KAZUHIKO
IPC: B41J2/01
Filed: 2001-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for obtaining high preservability which cannot be realized by a conventional technique in an ink jet image forming method by the coating of a film using a simple apparatus.  <P>SOLUTION: After an image is formed on ink jet image receiving paper, a film having microcapsules discharging an adhesive of a core substance under pressure provided on the single surface thereof is bonded to the surface of the image under pressure.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003193675-A (JP)
Title: Stair for temporary scaffold and integral type handrail frame for installing stair opening section
Inventor: ISHISE JUNICHI
IPC: E04G5/00
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To prevent the reduction of a working space generated when a handrail frame for stairs and a handrail frame for a stair opening section are installed respectively in a temporary scaffold.  <P>SOLUTION: In the handrail frame 1 for the stair opening section, one 1d of the left-right side frame sections 1d and 1b of the handrail frame 1 is fixed onto the horizontal member A' of one A of building frames A and B parallel through a fixture 3, and the other 1b is fixed and installed onto the side girder 15' of the stairs 15 through the fixture 2. In the handrail 11 for the stairs, the frame upper section 11 of the handrail frame 11 is suspended from the frame lower section 1c of the handrail frame 1 for the stair opening section through the fixtures 13, and a frame lower section 11c is fixed and mounted onto the side girder 15' of the stairs 15 through the fixture 14. Accordingly, the handrail frame 1 for the stair opening section and the handrail frame 11 for the stairs are connected vertically in the same perpendicular.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003197395-A (JP)
Title: Atmospheric pressure glow discharge generator and static eliminator
Inventor: OSAWA ATSUSHI
IPC: H01T23/00
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide an atmospheric pressure glow discharge generator capable of generating stable glow discharge at an atmospheric pressure and applicable to a static eliminator generating no ozone and having good ion balance.  <P>SOLUTION: This atmospheric pressure glow discharge generator generating stable glow discharge at the atmosphere pressure is provided with a bump electrode 1 having a protrusion 11, a hollow electrode 2 having a small hole part 21 facing the protrusion 11, and a power source 41 generating alternating current to be pressed to the bump electrode 1. The dimension of the small hole part 21 in the hollow electrode 2 is 0.1-0.5 mm, and an interval between the bump electrode 1 and the hollow electrode 2 is 0.2 mm or less.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003502662-A (JP)
Title: 埋設された織物強度担体を備えたポリマー材料から成る偏平製品の検査装置
IPC: G01R33/38
Filed: 2000-06-16
Abstract: (57)【要約】
埋設された織物強度担体を備えたポリマー材料から成る偏平製品の検査のための装置であって、この装置によってポリマー材料中の強度担体の配列及び延在方向が、破壊することなしにかつ偏平製品の品質を損なうことなしに確認可能である。偏平製品の核磁気共鳴による分析のためのＮＭＲ−ＭＯＵＳＥプローブが使用される。ＮＭＲ−ＭＯＵＳＥゾンデ（９ａ、９ｂ、９ｃ）は、測定体１上に偏平製品３の支持のための測定平面を形成しかつ測定平面内で好ましくは材料の検査方向に相互に重なって配設されている。
Patent JP-2003529682-A (JP)
IPC: B26F3/00
Filed: 2000-05-22
Abstract: A mechanism for the treatment of materials by pressurized water jets includes a body (1) for supplying water under pressure which includes a feeding chamber (2) extending over the whole length of the body, and wherein water under pressure is fed to the feeding chamber through a filter (4). The body also includes a distributing zone for distributing water under pressure over a whole treatment length against a plate (7) provided with micro-perforations which define water needles (8) directed against the surface (S) of the material to be treated. The material is supported by a carriage element subjected to a suction source eliminating the treatment water. Further, water transfer from the intake chamber (2) to the perforated plate (7), is done through a channel (22) with a rectangular cross-section extending over the whole length of the injector, from the periphery of the feeding chamber (2) up to the surface or the perforated plate (7), wherein the spacing between the side walls (21) of the channel and the height thereof produces a unidirectional and stable stream of water without turbulence.
Patent JP-2003504843-A (JP)
Title: ウェハ洗浄システムの処理前調整を確認するための方法
IPC: H01L21/304
Filed: 2000-06-28
Abstract: (57)【要約】
【課題】
【解決手段】  ウェハ洗浄システムに対する処理前調整を確認するための方法は、（ａ）ウェハ洗浄システムに対して処理前調整を実施するステップ（２００）と、（ｂ）略透明なウェハをウェハ洗浄システム内に搭載するステップ（２０２）と、（ｃ）略透明なウェハがウェハ移送経路に沿ってウェハ洗浄システム内を移動する状態を観察するステップ（２０４）と、を含む。略透明なウェハとウェハ洗浄システムの構成要素との間に望ましくない接触が観察された場合（２０６）には、方法は、（ｄ）処理される半導体ウェハとウェハ洗浄システムの構成要素との間における望ましくない接触を回避するよう意図された調整を、ウェハ洗浄システムに対して実施するステップ（２０８）と、（ｅ）略透明なウェハが、ウェハ洗浄システムの構成要素と望ましくない接触をせずにウェハ移送経路に沿って移動するまで、ステップ（ｂ）乃至（ｄ）を繰り返すステップと、を更に含む。方法は、すすぎ操作の最中ウェハの下方からスプレーされる液体がウェハの下面に適切に降りかかっていることを確認するためにも、略透明なウェハの観察を含むことができる。
Patent JP-2003505589-A (JP)
Title: 物品の被覆方法
IPC: A63B53/00
Filed: 2000-07-19
Abstract: (57)【要約】
【解決手段】加工品（18）を被覆する方法において、Ｎ個の非工業的材料塊（18）の群を真空室（10）内に設置し、その個数Ｎを各材料塊（18）のコストの関数とし、プラズマ発生機構（20）により前記群の周りにプラズマを発生させ、高圧電源（22）と高圧モジュレータ（24）とフィードスルー（26）とを介して電流を前記群へ加え、該電流の大きさを前記群中の材料塊の個数Ｎに依存させ、且つ前記プラズマのイオンにより前記群の各材料塊を十分被覆するように前記電流の大きさを調整する。
Patent JP-2003505403-A (JP)
Title: 経鼻抗痙攣組成物及び調節方法
IPC: A61K31/4166
Filed: 2000-07-24
Abstract: (57)【要約】
媒体によって調節して、ヒト及び動物の粘膜に抗痙攣剤を投与する新規な方法を開示する。媒体系は、胆汁塩又はレシチンのような生物学的活性剤と共に、脂肪族アルコール（１０−８０％）、又はグリコール（１０−８０％）、及びそれらの組み合わせを含む、水性の薬学的担体である。薬学的組成物は、１回又は複数回投与することにより、粘膜を介した薬剤の浸透及び吸収の速度及び量を調節及び促進するための手段を提供する。薬学的組成物の経鼻投与は、静脈内投与と同じ位素早く、抗痙攣剤の高い血漿濃度をもたらす。そのような組成物は、発作重積状態及び他の発熱によって引き起こされる発作の救急及び／又は緊急治療における、患者の迅速かつ適時の薬物治療に特に適している。
Patent JP-2003505410-A (JP)
Title: 速放性押出物、その製造方法および該押出物から得られる製剤
IPC: A61K9/36
Filed: 2000-07-12
Abstract: (57)【要約】
本発明は、低粘度ヒドロキシプロピルセルロースおよび少くとも１種の活性成分を含有する安定な速放性押出物に関する。本発明はまた、溶媒を使用しない該押出物の製造方法に加えて速放性製剤の製造における該押出物の使用に関する。
Patent JP-2003510021-A (JP)
IPC: C12Q1/68
Filed: 2000-07-28
Abstract: Described are general means and methods of diagnosing and treating the phenotypic spectrum as well as the overlapping clinical characteristics with several forms of inherited abnormal expression and/or function of the Multi Drug Resistance-1 (MDR-1) gene. In particular, polynucleotides of molecular variant MDR-1 genes which, for example, are associated with unsufficient and/or altered uptake of drugs by a target cell, and vectors comprising such polynucleotides are provided. Furthermore, host cells comprising such polynucleotides or vectors and their use for the production of variant MDR-1 proteins are described. In addition, variant MDR-1 proteins and antibodies specifically recognizing such proteins as well as concerns transgenic non-human animals comprising the above-described polynucleotide or vectors are provided. Described are also methods for identifying and obtaining inhibitors for therapy of disorders related to the malfunction of the MDR-1 gene as well as methods of diagnosing the status of such disorders. Pharmaceutical and diagnostic compositions comprising the above-described polynucleotides, vectors, proteins, antibodies and inhibitors by the above-described method are provided. Said compositions are particularly useful for diagnosing and treating various diseases with drugs that are substrates, inhibitors or modulators of the MDR-1 gene product.
Patent JP-2003509891-A (JP)
Title: 通信システムにおいて電池を節約する方法
IPC: H04B1/16
Filed: 2000-08-15
Abstract: (57)【要約】
受信器（３４）が中央局から送信を受信するために定期的に活性化される遠隔計測システムのような通信システムにおいて、受信器は、受信器の活性化を制御する電力制御手段（１２）と、搬送波の存在を検出し、搬送波が検出されない場合に電力制御手段に受信器（３４）を非活性化させる回路（４８）と、復調された信号が復号可能かを決定し信号の質が受け入れられない場合に電力制御手段に受信器（３４）を非活性化させる信号の質を測定する段（５０）とを有する。
Patent JP-2003528290-A (JP)
Title: 楕円偏光法及び反射偏光法のための空間的平均化技術
IPC: G01N21/21
Filed: 2000-09-13
Abstract: (57)【要約】
【構成】  本発明は楕円偏光法及び反射偏光法光学測定機器に関し、これらは半導体ウェハを評価するのに用いられ、且つ所望の測定領域又はパッドを取り囲む材料に関連した誤差を低減することを意図している。本発明の一つの局面は、光スポットが測定パッド上を走査するにつれて小さなステージジョグにより一連の測定の分離がなされる技術を利用する。与えられた周辺材料はパッドの両側で同一であり、データ不変性は、位置の関数として見たときにカップ状又は逆Ｕ字状か、或いは逆カップ状又は  Ｕ字状の何れかを有することが見出される。曲線の最小値又は最大値がパッドの中心を識別するのに用いられる。パッドの中心で集められたデータは、パッド材料からの到来光と周辺材料からの到来光との重ね合わせにより形成されたものとして調整される。
Patent JP-2003511699-A (JP)
IPC: G01N27/327
Filed: 2000-09-12
Abstract: A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
Patent JP-2004508275-A (JP)
IPC: A61K8/00
Filed: 2000-10-18
Abstract: The invention concerns novel oxidative compositions for dyeing keratinous fibres comprising at least a 3-amino-pyrazolo-[1,5-a]-pyridine of Formula (I), the dyeing method using said composition, novel 3-amino pyrazolo-[1,5-a]-pyridines, and the method for preparing them.
Patent JP-2003515968-A (JP)
Title: インターネット・プロトコル電話の音声／ビデオ・メッセージの預託および検索
IPC: H04L12/58
Filed: 2000-11-08
Abstract: (57)【要約】
メッセージを預託するために、インターネット・プロトコル（ＩＰ）をベースとするネットワーク上の内蔵メッセージ通信システム（ＩＭＳ）に信号を送るための方法であって、ＩＭＳに、メッセージ預託動作を表示するセッション開始プロトコル（ＳＩＰ）ＩＮＶＩＴＥ要求を送信するステップと；ＩＭＳから、メッセージ預託動作に参加することに同意する対応するＳＩＰメッセージを受信するステップと；ＩＭＳに、上記対応するＳＩＰメッセージの受信を確認するＳＩＰ受信通知メッセージを送信するステップと；メッセージを宛先メールボックス内に預託するステップとを含む方法。
Patent JP-2004502398-A (JP)
IPC: H01R39/06
Filed: 2000-11-23
Abstract: A flat commutator for an electrical machine comprises a support body (1) made of an insulating molding compound, a plurality of conductor segments (3) and an equal number of carbon segments (4), which are disposed at the ends and are connected in electrically conductive relationship to the conductor segments (3). Each of the conductor segments (3) is provided with a thick-walled terminal region (6) disposed on the periphery of the support body (1), a contact region (7), which is also thick-walled, disposed between the support body (1) and the associated carbon segment (4), and a thin-walled transition region (8) disposed between the terminal region (6) and the contact region (7).
Patent JP-2003517476-A (JP)
IPC: A61K31/439
Filed: 2000-11-29
Abstract: Novel methods for the treatment and/or prevention of ileus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaternary benzomorphans. The methods are particularly suitable for treating and/or preventing postsurgical ileus and postpartum ileus.
Patent JP-2003519989-A (JP)
Title: 隣接マクロブロックを用いた動き推定方法及び装置
IPC: H04N7/26
Filed: 2000-12-28
Abstract: (57)【要約】
ビデオ画像データの２フレーム間の動きベクトルを得る動き推定方法及び装置を開示する。特に、本発明の動き推定方法及び装置は、参照フレームに対する現フレームの各マクロブロックの動きベクトルを多段処理により推定するのに用いることができる。
Patent JP-2003519486-A (JP)
IPC: A61K35/14
Filed: 2001-01-09
Abstract: A rapid, simple-to-use method for preparing hybrid cells, applicable to fully differentiate, non-dividing cells, entails bringing at least two different cells into contact under conditions that promote cell fusion and then purifying the resultant hybrid without antibiotic or metabolic selection. This approach yields hybrid cells useful in a variety of applications, including clinical treatment regimens, as cellular modulators of the immune system.
Patent JP-2003521163-A (JP)
Title: テキスト改良
IPC: G09G5/36
Filed: 2000-12-22
Abstract: (57)【要約】
テキスト改良の方法であって、画像テキストが検出され、画像のライン当たりの画素及び画像当たりのラインに関する第１の数を、前記画像が表示されるべきディスプレイに適合するライン当たりの画素及び画像当たりのラインに関する第２の数に調整するように前記画像がスケーリングされ、前記テキスト検出の結果に依存して前記画像が処理される。
Patent JP-2003522629-A (JP)
IPC: B01D3/20
Filed: 2001-02-16
Abstract: Gas-liquid contact tray comprising a bubble area and a plurality of downcomers having a downcomer opening, which downcomer openings are spaced in the bubble area, such that, when in use, a liquid enters the downcomer opening from opposite sides of the downcomer opening, wherein the downcomer opening and downcomer is provided with at least two flow directing plates, wherein each flow directing plate has an upper end which extends above the tray and is inclined towards the direction of the liquid flowing towards the downcomer opening.
Patent JP-2003525358-A (JP)
Title: プロピレン耐衝撃性コポリマーで製造された繊維及び布
IPC: D01F6/30
Filed: 2001-01-26
Abstract: (57)【要約】
本発明は一般的に新規な繊維と布に関する。具体的には、これらの繊維はプロピレン耐衝撃性コポリマー組成物を使用して製造される。これらの繊維から形成された布、特に不織布は、改良された伸び特性を示す。
Patent JP-2003526582-A (JP)
Title: ジッパー付きの再シール可能なエンクロージャ
IPC: B65D33/25
Filed: 2001-03-15
Abstract: (57)【要約】
【課題】ファスナアセンブリのためのジッパー断面形状を提供する。
【解決手段】断面形状は雄要素（１０６）と雌要素（１００）を含む。雌要素は、共通のてこ支点領域（１０２）に関して互いに可動な一対のあご（１０１，１２１）と、それぞれが前記てこ支点領域において前記一対のあごに繋がれた一対のアーム（１０３，１２３）を含む。各アームはてこ支点領域の反対側に位置する端部（１０４，１０５）を有し、この端部はスライダ（２０８）と係合する形状に設けられている。一対のあごは開位置と閉位置を有する。アームは、それがてこ支点領域回りに変位するときに、あごを閉位置と開位置の間に移動させるように配設されている。てこ支点領域回りの変位はアームに対するスライダの移動によってなされる。雌要素は、あごが閉位置にあるときに雄要素によって捕捉され、あごが開位置にあるときに解放される。
Patent JP-2003532645-A (JP)
Title: 血漿アスコルビン酸の枯渇方法
IPC: A61K47/48
Filed: 2000-05-02
Abstract: (57)【要約】
アスコルビン酸をde novo合成できるマウスにおける人為的なアスコルビン酸濃度制御が研究された。マウスに外来性アスコルビン酸またはその生理学的前駆体であるL-グロノ-γ-ラクトンを投与すると、そのアスコルビン酸の血漿内濃度がかなり増加したがすぐに基礎濃度に戻った。同様に、アスコルビン酸キシダーゼの投与は急速な血漿内アスコルビン酸の枯渇を生じさせたが、続いて急速にアスコルビン酸が回復した。これらの結果は、動物におけるアスコルビン酸の制御において困難に遭遇することを示すものである。しかし、メトキシポリエチレングリコールで化学的修飾をすることによって動物において外来性アスコルビン酸キシダーゼの循環寿命が成功裡に延長された。その修飾酵素は総酵素活性を保持したまま未改変酵素と比較して血漿内アスコルビン酸の枯渇期間を顕著に延長した。化学的に修飾されたアスコルビン酸キシダーゼはアスコルビン酸合成動物においても食餌制限なしに血漿内アスコルビン酸を枯渇できるため、前記の研究を通じて化学的に修飾されたアスコルビン酸キシダーゼはアスコルビン酸関連動物研究において多くの用途に使用することができる。また、アスコルビン酸濃度操作に感受性のマウスおよびヒトの腫瘍系が存在するので、この酵素は腫瘍抑制に有用と考えられる。
Patent JP-2003202193-A (JP)
Title: Heat exchanger including plurality of passages to be heated
Inventor: KATSUKI HIROSHI
IPC: B01F15/06
Filed: 2002-01-07
Abstract: <P>PROBLEM TO BE SOLVED: To provide a heat exchanger of high heating efficiency without necessity of using a batch tank for storing a medium for heating a flowing body as an object of heat exchange.  <P>SOLUTION: This heat exchanger includes a thermal conductive column shaped body 2 including a bundle of a plurality of passages which flowing body flow of the object of heat exchange can branch out and flow in and a tubular heat generating part 3 surrounding whole outer periphery of the column shaped body and heating the outer peripheral side of the column shaped body. The plurality of the passages exist in the outer peripheral part of the column shaped body which is adjacent to the heat generating part 3 and is heated at high efficiency.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003209677-A (JP)
Title: Image data, image data processing method and image data processing program
Inventor: TAKADA KOKUFUKU
IPC: H04N1/387
Filed: 2002-01-10
Abstract: <P>PROBLEM TO BE SOLVED: To provide an image data, an image data processing method and an image data processing program which can print or display an image normally only under prescribed conditions.  <P>SOLUTION: A CPU 21 receives a print requirement of the image based on a RGB image data having an image information embedding a digital reverse watermark and an image additional information having an address of each pixel to correspond to the digital reverse watermark area of the image information and the original RGB value of the pixel. The CPU 21 specifies the address of each pixel to correspond to the digital reverse watermark area and replaces the RGB value of each pixel to correspond to the digital reverse watermark area with the original RGB value. The CPU 21 forms the image data which erases the digital reverse watermark by the replacement of all RGB values in the digital reverse watermark area and outputs an original image which does not display the watermark based on the digital reverse watermark.  <P>COPYRIGHT: (C)2003,JPO