baber/WOPTO huggingface dataset:
Patent RU-2732405-C2 (RU)
Inventor: CUI JINGRONG J
IPC: C07D498/22
Filed: 2016-06-30
Granted: 2020-09-16
Abstract: Изобретение относится к соединению формулы I или к его фармацевтически приемлемой соли, где M представляет собой CRили N; Mпредставляет собой CRили N; Xпредставляет собой N(R); Xпредставляет собой O; Rпредставляет собой H или C-Cалкил; где каждый атом водорода в C-Cалкиле независимо необязательно замещен дейтерием, галогеном, -OH, -CN, -OC-Cалкилом, -NH, -NH(C-Cалкил), -N(C-Cалкил), -NHC(O)C-Cалкилом, -N(C-Cалкил)C(O)C-Cалкилом, -NHC(O)NH, -NHC(O)NHC-Cалкилом, -N(C-Cалкил)C(O)NH, -N(C-Cалкил)C(O)NHC-Cалкилом, -NHC(O)N(C-Cалкил), -N(CCалкил)C(O)N(C-Cалкил), -NHC(O)OC-Cалкилом, -N(C-Cалкил)C(O)OC-Cалкилом, -NHS(O)(C-Cалкил), -NHS(O)(C-Cалкил), -N(C-Cалкил)S(O)(C-Cалкил), -N(C-Cалкил)S(O)(C-Cалкил)-NHS(O)NH, -NHS(O)NH, -N(C-Cалкил)S(O)NH, -N(C-Cалкил)S(O)NH, -NHS(O)NH(C-Cалкил), -NHS(O)NH(C-Cалкил), -NHS(O)N(C-Cалкил), -NHS(O)N(C-Cалкил), -N(C-Cалкил)S(O)NH(C-Cалкил), -N(C-Cалкил)S(O)NH(C-Cалкил), -N(C-Cалкил)S(O)N(C-Cалкил), -N(C-Cалкил)S(O)N(C-Cалкил), -COH, -C(O)OC-Cалкилом, -C(O)NH, -C(O)NH(C-Cалкил), или -C(O)N(C-Cалкил), -SC-Cалкилом, -S(O)C-Cалкилом,-S(O)C-Cалкилом, -S(O)NH(C-Cалкил), -S(O)NH(C-Cалкил), -S(O)N(C-Cалкил), -S(O)N(C-Cалкил), -P(C-Cалкил), -P(O)(C-Cалкил), C-Cциклоалкилом или 3-7-членным гетероциклоалкилом; Rи R, совместно с атомами углерода, к которым они присоединены, образуют C-Cциклоалкил или 5-7-членный гетероциклоалкил; или Rи Rсовместно с атомами, к которым они присоединены, образуют 5-7-членный гетероциклоалкил, и Rпредставляет собой Н; каждый из R, Rи Rнезависимо представляет собой H, фтор, хлор или бром; Rпредставляет собой H, или, совместно с Rи атомами, к которым они присоединены, образует 5-7-членный гетероциклоалкил; каждый Rпредставляет собой H; каждый Z, Zи Zпредставляют собой N; Z, Zи Zпредставляют собой СН; Zпредставляет собой –С-; n равен 1 или 2. Изобретение также относится к способу лечения и ингибирования протеин- или тирозинкиназ на основе указанного соединения. Технический результат – получены новые соединения, которые могут найти применение в медицине для лечения рака. 5 н. и 12 з.п. ф-лы.I
Patent RU-2716822-C2 (RU)
Title: Disengaging mechanism for switch
Inventor: PAN BINHUA
IPC: H01H71/12
Filed: 2016-08-02
Granted: 2020-03-17
Abstract: FIELD: physics. 
     SUBSTANCE: invention relates to low-voltage devices. Disengaging mechanism for the switch comprises a connecting rod assembly and a control unit, wherein one end of the connecting rod assembly is drive connected to the rotary shaft assembly to bring the switch to the off position, and the other end of the connecting rod assembly is equipped with a transition plate, which can be connected to the control unit in a locking manner, and the adapter plate is also equipped with a U-shaped slot. Control unit includes a switching latch installed with possibility of rotation. Switching latch end is configured to be connected to the U-shaped slot in a lockable and restrictive manner, and when switched off, the switch disengages the switch-off latch end part from the U-shaped slot, whereby the rotary shaft connected to the connecting rod assembly switches the switch to the off-position. 
     EFFECT: disengaging mechanism for the switch provided by the present invention is characterized by stability of locking, simplicity of design and accuracy of operation. 
     10 cl, 31 dwg
Patent RU-2709925-C2 (RU)
Title: Method of supplying continuous sheet of aerosol-forming substrate from roll and aerosol-forming article
Inventor: KLIPFEL YORICK
IPC: A24C5/01
Filed: 2016-10-21
Granted: 2019-12-23
Abstract: FIELD: smoking accessories. 
     SUBSTANCE: method for supplying a continuous sheet of aerosol-forming substrate (10) from roll (1) includes steps of providing roll (1) of a continuous sheet of aerosol-forming substrate (10) and unwinding said continuous sheet of aerosol-forming substrate (10) from centre of roll (1). Preferably, creation of torque on roll (1) is prevented during unwinding of continuous sheet of aerosol-forming substrate (10). 
     EFFECT: disclosed is a method of feeding a continuous sheet of aerosol-forming substrate from the roll and an aerosol-forming article. 
     15 cl, 6 dwg
Patent RU-2766583-C2 (RU)
Inventor: QU GUANG
IPC: A61K31/7088
Filed: 2016-12-01
Granted: 2022-03-15
Abstract: Изобретение относится к биотехнологии. Описывают способы и композиции для трансфекции клеток с использованием плазмид. В определенных вариантах осуществления описывают способы и композиции, в которых эффективность трансфекции значительно повышают посредством приведения трансдуцированных клеток в контакт с полиэтиленимином (PEI), не содержащим нуклеиновую кислоту, в течение трансфекции. Также описывают терапевтически применимые векторы на основе аденоассоциированных вирусов, полученные с использованием описываемых способов и композиций. Изобретение расширяет арсенал терапевтических средств. 6 н. и 52 з.п. ф-лы, 6 ил., 2 табл., 5 пр.
Patent RU-2746352-C2 (RU)
Inventor: KRASNOV ALEXEY
IPC: E04B1/84
Filed: 2017-02-23
Granted: 2021-04-12
Abstract: FIELD: acoustics.   
     SUBSTANCE: invention relates to an acoustic wall unit as well as a wall retrofit kit for providing such an acoustic wall unit. The acoustic wall unit has internal and external walls, which are essentially parallel to each other and there is a gap between them. The acoustic wall unit also has an air pump located in the gap; and a sound masking circuit configured to detect sound waves in a predetermined frequency range, and in response to the detection of sound waves in a predetermined frequency range of air pump control to inject air into the gap to actively mask the detected sound waves as they pass from the outside the outer wall to the inner side of the inner wall, while active masking is performed using reverberation; wherein at least one of the inner and outer walls contains glass, wherein the air pump is controlled by a sound masking circuit to create a dynamic non-point source of reverberant noise that is suppressed and substantially uniform across the gap. Reverberation noise is generated on demand to disorganize the intelligibility of the detected sound waves as they pass from the outside of the outer wall to the inside of the inner wall; and the technical result is achieved with a wall retrofit kit to provide such an acoustic wall unit. 
     EFFECT: soundproofing.  
     8 cl, 13 dwg, 1 tbl
Patent RU-2723703-C2 (RU)
Inventor: RINGEMANN Kristian
IPC: A61B5/145
Filed: 2017-05-03
Granted: 2020-06-17
Abstract: Группа изобретений относится к области биотехнологии. Предложен сенсорный прибор и сенсорный комплект для определения аналита в физиологической среде пользователя, способ обработки потока данных зависящей от времени концентрации аналита в физиологической среде пользователя. Сенсорный прибор включает содержащее сравнивающее устройство аналитическое устройство, где сравнивающее устройство выполнено с возможностью сравнения текущего значения концентрации с первым и вторым пороговыми значениями. Причем аналитическое устройство выполнено с возможностью анализа потока данных зависящей от времени концентрации аналита, задания временного интервала нечувствительности, обнаружения повышения концентрации и превышения ею первого порогового значения, подготовки сигнала предупреждения, подавления выдачи сигнала предупреждения и выдачи сигнала предупреждения при превышении концентрацией аналита второго порогового значения. Сенсорный комплект содержит сенсорный прибор и выполненный с возможностью мониторирования зависящей от времени концентрации аналита в физиологической среде сенсор. Способ включает сравнение текущего значения концентрации с первым и вторым пороговыми значениями, задание временного интервала нечувствительности, обнаружение повышения концентрации и превышения ею первого порогового значения, подготовку сигнала предупреждения, подавление выдачи сигнала предупреждения и выдачу сигнала предупреждения при превышении концентрацией аналита второго порогового значения. Изобретения обеспечивают повышение достоверности сигнала предупреждения, указывающего пользователю на необходимость принятия мер по снижению концентрации аналита, а также предотвращение слишком частой выдачи таких сигналов предупреждения, когда поведение концентрации аналита позволяет надежно отложить выдачу предупреждения. 3 н. и 12 з.п. ф-лы, 5 ил.
Patent UA-58588-C2 (UA)
Title: Stand for testing separable load handling devices
Inventor: SHVIDLER OLEKSANDR PETROVYCH
Filed: 2000-10-09
Abstract: The present invention relates to crane equipment, specifically to stands designed for testing separable cable or chain load handling devices, which include two-leg or multi-leg slings. The proposed stand contains a casing, fixed elements, a movable element that is mounted on the guide parts of the casing, and an electric drive. The stand fixed elements are sequentially positioned and spaced at specified intervals. The stand movable element is designed as a carriage with side posts, which are connected by traverses. The proposed design provides for the possibility to extend the stand functionality range and decrease the stand cost.
Patent UA-72221-C2 (UA)
Title: Inulin fraction, method of obtaining thereof and food products containing the inulin fraction stated
IPC: A23L27/30
Filed: 1999-08-25
Abstract: Products containing inulin fractions having molecular weight ranges, processes for making such products, and food products containing such inulin fraction products.
Patent UA-68434-C2 (UA)
Title: Hose device
IPC: A01J7/00
Filed: 2000-06-07
Abstract: A hose device includes a hose portion (3), at least a first end portion (2) and a channel (5) which extends along the hose device (1) through the first end portion and the hose portion. The hose device has flexible and elastic properties. The first end portion (2) of the hose device is in a mounted state arranged to be attached to a tubular connection member (7) by having the connection member introduced in the channel (5). The hose device has a transition portion (4), which is located between the first end portion (2) and the hose portion (3). The channel (5) thus extends also through the transition portion and has, at the transition portion (4), in a non-mounted state a non-circular cross-sectional shape and in the mounted state a substantially circular cross-sectional shape, which permits a free liquid flow through the channel (5).
Patent UA-82649-C2 (UA)
Title: Blade and rotary unit of turbo-jet motor
Inventor: TALBOTEC JEROME
IPC: F01D5/12
Filed: 2004-02-27
Abstract: A rotary turbojet blade comprises a plurality of blade sections extending along a line of the centers of gravity of said sections between a base and a tip, said blade presenting along a radial axis a bottom portion, an intermediate portion, and a top portion, said bottom portion presenting a longitudinal angle of inclination for a leading edge line, said intermediate portion presenting a backward longitudinal angle of inclination for said leading edge line, and said top portion presenting a backward longitudinal angle of inclination for said leading edge line and a tangential angle of inclination for said line of the centers of gravity in a direction opposite to the direction of rotation of said blade. EMBED Equation.3
Patent UA-83645-C2 (UA)
Title: Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors
Inventor: MOEBIUS HANS-JOERG
IPC: A61K31/55
Filed: 2003-10-23
Abstract: A drug combination therapy useful in the treatment of dementia associated with disorders of the central nervous system, e.g. to delay the onset or progression of Alzheimer's disease, cerebrovascular disease or Down's syndrome, comprises a combination of a 1-aminocyclohexane derivative such as memantine or neramexane and an acetylcholinesterase inhibitor such as galantamine, tacrine, donepezil or rivastigmine.
Patent UA-83357-C2 (UA)
Title: Sea ice-proof platform
Inventor: LENSKYI VIKTOR FEDOROVYCH
IPC: B63B35/44
Filed: 2005-07-11
Abstract: A sea ice-proof platform has upper structure connected to support basis by means of support columns on which anti-ice barrier as inclined bulb. At that the bulb is placed at perimeter in zone of ice loads and is made closed in perimeter of platform and surrounding support columns in outer diameter, in the upper part of the bulb additional ice-protective inclined ledge is arranged, the ledge is directed in direction opposite to the inclined bulb and placed at angle not less than 8° to vertical direction, and ratio of height of the additional inclined ledge to height of inclined bulb is not less than 0.08. Technical result is in increase of reliability and safety of operation of platform in ice conditions.
Patent UA-79365-C2 (UA)
Title: Device for root transportation and cleaning
Inventor: BULHAKOV VOLODYMYR MYKHAILOVYC
IPC: A01D33/08
Filed: 2005-10-10
Abstract: A device for root transportation and cleaning consists of a basic frame, a feeding table, a baffle brush, a grating cleaner which has a form of cone, an activator in the form of actuating cylindrical brush as well as a gravity separator and an unloader. The activator is made as two actuating cylindrical brushes mounted alongside, which are in counterrotation directed to the lower internal hollow of the cone-shaped cleaner, and above their upper part a figured baffle is fixed, this is located above interbrush space.
Patent UA-85849-C2 (UA)
Title: Installation for intensification of deposit dewatering at mud fields
Inventor: BOLOTSKYKH MYKOLA STEPANOVYCH
Filed: 2006-04-11
Abstract: The invention relates to equipment for dewatering liquid masses at mud fields equipped with draining system. Installation consists of suction mains connected to draining system, vessel for separation of gas-liquid mix, vacuum pump connected to it. Installation for liquid discharge is arranged as vertical unloading vessel immersed to water-intake well, with control pressure release valve installed in its lower part. In the upper part of the vessel for separation of gas-liquid mix safety pressure valve is installed. Installation makes it possible to decrease power consumption, to increase efficiency, to simplify design and to intensify process of dewatering deposits on mud fields.
Patent UA-89781-C2 (UA)
Title: Liquid growth hormone formulation
Inventor: ARVINTE TUDOR
IPC: A61P5/02
Filed: 2005-03-30
Abstract: The invention relates to a liquid formulation comprising a growth hormone; a citrate/phosphate buffer, an alkali metal salt and an alkaline earth metal salt or a pseudo alkaline earth metal salt, a polyethylene-polypropylene glycol.
Patent UA-87356-C2 (UA)
Title: Re-circulation installation for aerodynamical heating
Inventor: IVANOV DMYTRO HEORHIIOVYCH
IPC: F24J3/00
Filed: 2007-08-28
Abstract: The invention relates to heat engineering, in particular to installations for aerodynamical heating of gaseous media. Re-circulation installation has ventilator with rotor and rotary drive. It is placed in cavity connected to heating chamber with suction and supercharge pipelines. At outlet end of reamed part of heating pipeline additional aerodynamical heater is installed, as flat vortex chamber. In additional heater gas flows are swirled as spirals. Device in turns operate in direct-flow and re-circulation modes. The invention promotes more effective heating of air.
Patent UA-98293-C2 (UA)
Title: Driving unit for a grain combined harvester
Inventor: BUCHMAN NORBERT
IPC: A01D41/12
Filed: 2007-09-14
Abstract: A grain combined harvester is applied. Said combined harvester comprises a driving unit with one or several separating rotors, arranged along the moving direction of the combined harvester, and a straw cutter, which is arranged under an unloading area of the separating rotors transversally to the moving direction of the combined harvester. Transfer of the power of the drive is carried out through a resilient embracing gear. The separating rotors (5) and the straw cutter (6) are made in such a manner as to allow joint putting into action with the aid of at least one resilient embracing gear (25, 29, 35). The gears are jointly arranged on a side wall of the grain combined harvester (1).
Patent UA-87749-C2 (UA)
Title: Out-of-furnace aluminothermal method for obtainig of ferrovanadium
Inventor: BOIKO VOLODYMYR SEMENOVYCH
IPC: C22B34/22
Filed: 2007-11-26
Abstract: The invention relates to metallurgy, namely to the production of ferroalloys with aluminothermal method. An out-of-furnace aluminothermal method for obtaining of ferrovanadium comprises the preparation of charge – vanadium-containing material with introduction into it of reducing agent – ferroaluminium alloy or aluminium powder, or their mix and fining mix, which is loaded on the bottom of smelting unit, at that reducing agent and vanadium-containing material in charge are differentially distributed, two independent particles of charge, at that in the top part of charge is introduced of 85÷95 w/w of vanadium-containing material, intended for melting, all reducing agent, which makes of aluminium surplus of 130±5 % from stoichiometric necessary for reduction of vanadium, and fluxing impurities, and in the bottom part of charge is introduced of surplus of 5÷15 w/w of vanadium-containing material and fluxing impurities. The smelting of ferrovanadium on this method will allow increase of vanadium extraction in finished product with out-of-furnace method and without additional power inputs.
Patent UA-90147-C2 (UA)
Title: Electromechanical circuit breaker and a method for breaking the current in said electromechanical circuit breaker
Inventor: MARTIN SERGE
IPC: H01H9/00
Filed: 2006-06-12
Abstract: The electromechanical circuit breaker is intended to establish and break the current in a main circuit (3, 4) and comprises a fixed contact clement (5) and a moving contact clement (6) which in a first position arc in electrical contact with each other for carrying the current of the main circuit (3, 4). Said moving contact element (6) is adapted to be displaced to a second position in which it is separated from the fixed contact element (5) so that the current in the main circuit is cut off. The circuit breaker is provided with a blow-out device (2) comprising a magnetising coil (8) traversed by a magnetising current for producing a magnetic field (26) adapted to drive an arc generated by the separation of said two contact elements (5, 6) into an arc extinction means. The blow-out device (2) comprises electrodes (12) electrically connected to the magnetising coil (8) and adapted to cooperate with said arc in such a manner that the latter generates said magnetising current in the magnetising coil (8). The magnetic field for driving the arc is generated by the action of said arc. Said electrodes (12) arc located in such a relationship with said contact elements (5, 6) that the arc generated by the separation of said two contact elements is at least partially separated into a first arc (13a) between one contact element (5) and the electrodes (12) and a second arc (13b) between the electrodes (12) and the other contact element (6). Said first or second arc (13a, 13b) is set in parallel coupling with said magnetising coil (8) connected on one side to the electrodes (12) and on the other side to one of the contact elements (5, 6). These features allow to obtain high breaking efficiency and performances even when breaking smaller currents.
Patent UA-95613-C2 (UA)
Title: Compounds for the treatment of metabolic disorders
Inventor: ROMANTSEV FEDOR EVGENIEVICH
IPC: A61K31/216
Filed: 2006-09-11
Abstract: Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, poly-l cystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. (Formula I)wherein n is 1 or 2; one of m and x is 0 and the other is 0,1, 2, 3, or 4; q is 0 or 1; t is 0 or 1; Ris alkyl having from 1 to 3 carbon atoms; Ris hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms; one of Rand Ris alkyl having from 1 to 3 carbon atoms and the other is hydrogen or alkyl having from 1 to 3 carbon atoms; A is phenyl, unsubstituted or substituted by 1 or 2 groups selected from: halo, alkyl having 1 or 2 carbon atoms, perfluoromethyl, alkoxy having 1 or 2 carbon atoms, and perfluoromethoxy; or cycloalkyl having from 3 to 6 ring carbon atoms wherein the cycloalkyl is unsubstituted or one or two ring carbons are independently mono-substituted by methyl or ethyl; or a 5 or 6 membered heteroaromatic ring having 1 or 2 ring heteroatoms selected from N, S and O and the heteroaromatic ring is covalently bound to the remainder of the compound of formula T by a ring carbon; and Ris hydrogen or alkyl having 1 or 2 carbon atoms. Alternatively, when Ris hydrogen, the biologically active agent can be a pharmaceutically acceptable salt of the compound of Formula I., (I)
Patent UA-95945-C2 (UA)
Title: Method for the treatment of prostate cancer comprosing androgen deprivation therapy in combination with imc-a12 administration
Inventor: LUDWIG DALE
IPC: A61P35/00
Filed: 2007-02-03
Abstract: The present invention relates to a method of treating prostate cancer with androgen deprivation therapy and an insulin-like growth factor receptor (IGF-IR) antagonist. Although the response rate of prostate cancer to androgen deprivation therapy (ADT) is high, surviving cancer cells invariably become androgen independent (AI) and tumor growth follows. The invention inhibits or delays transition of androgen dependent cancer to androgen independent cancer, significantly decreases risk of recurrence, and improves treatment outcome.
Patent UA-88589-C2 (UA)
Title: Weighting device for hydraulic loader
Inventor: BUHAIENKO HEORHII YAKOVYCH
IPC: G01G19/00
Filed: 2008-12-05
Abstract: Weighting device for hydraulic loader has indicators of pressure, analog-digital transformers to inputs of which outputs of pressure indicators are connected, and outputs of those are connected to input of processor block, indicator of angle of inclination that measures angle of inclination of loader with respect to horizon, its output is connected to input of processor block, this transforms signals of pressure indicators and indicator of angle of inclination and calculates mass of load in bucket, memory with autonomous power supply that stores results of count of mass of load, electrical interface for connection of power supply, electronic interface for transfer of weight data, and keyboard. Besides that the device has discrete indicator of beginning of measurement and discrete indicator of end of measurement outputs of which are connected to discrete inputs of processor block, respectively. Additionally device includes discrete indicator of position of bucket and indicator. Output of discrete indicator of position of bucket is connected to discrete input of processor block and parallel outputs of indicator and keyboard are connected to respective inputs of processor block, respectively.