baber/WOPTO huggingface dataset:
Patent AU-2019442607-A1 (AU)
Title: Target specific CRISPR mutant
Inventor: LEE JOON SUN
IPC: C12N15/11
Filed: 2019-04-26
Abstract: The present invention relates to an artificially modified CRISPR/Cas9 system. More particularly, the present invention relates to an artificially modified CRISPR enzyme having improved target specificity and to a use of an artificially modified CRISPR/Cas9 system comprising same in modification or engineering of a genome and/or epigenome, genome targeting, genome editing, and in vitro diagnosis.
Patent AU-2020202686-A1 (AU)
Title: A capstan winch
Inventor: MARRIOTT MICHAEL IAN
IPC: B66D1/74
Filed: 2020-04-22
Abstract: A capstan winch having a motor internal to the capstan which provides a bearing surface 
upon which the capstan may rotate. A gear assembly driven by a shaft of the motor 
rotates the capstan directly about the motor body. The gear assembly may be a pin 
5 cycloid gear drive which may be formed of a plastics material which, in use, expands to a 
desired shape. A main bearing may be provided at the top of the capstan to centralise 
the motor shaft to the capstan. The motor shaft is supported by a bottom bearing 
provided in a base support. The motor may be canter-levered from the base support so 
that the entire torque from the capstan is transmitted to the base support.  
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Figure 1
Patent AU-2020211435-A1 (AU)
Title: Systems and methods for applying energy to ovarian tissue
Inventor: GASPERMENT MARION
IPC: A61B17/34
Filed: 2020-01-23
Abstract: Described herein are methods and systems for performing a procedure for ovarian rebalancing. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may also be useful in the treatment of infertility associated with PCOS.
Patent AU-2020219262-A1 (AU)
Title: Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices
Inventor: CHAVAS JOËL
IPC: A61N5/06
Filed: 2020-02-04
Abstract: The present invention concerns a computer implemented method for controlling a device (40) adapted for projecting a light beam on at least a part of an eye of a wearer, the device (40) having an optical module comprising a light source (52), a pupil being defined for the part of the eye, the method comprising a step of providing the size of the pupil, determining a command law of the radiant power of the light source (52), the command law being determined on the provided pupil size, and sending the determined command law to the light source (52), wherein a maximum light intensity and a minimum light intensity are defined for the part of the eye and, at the step of determining, the command law further depends from at least one parameter selected in the group of the maximum light intensity and a minimum light intensity, each one of the maximum light intensity and the minimum light intensity varying spatially in the part of the eye.
Patent AU-2020223644-A1 (AU)
Title: Ultrasonic systems and methods with tissue resistance sensing
Inventor: COWLEY MATTHEW S
IPC: A61N7/02
Filed: 2020-08-25
Abstract: ULTRASONIC SYSTEMS AND METHODS WITH TISSUE RESISTANCE 
SENSING 
ABSTRACT 
Surgical systems include an ultrasonic device, a generator coupled to the ultrasonic device, and a 
return pad. The generator is configured to control supply of the ultrasonic energy to the 
ultrasonic device and control supply of an energy pulse to the ultrasonic device at different times.  
The ultrasonic device generates a current pulse signal in response to the energy pulse. The 
generator also measures a current feedback signal at the return pad, the current feedback signal 
resulting from the current pulse signal, and estimate a tissue property of tissue grasped by the 
ultrasonic device based on the current feedback signal.
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Patent AU-2020227132-A1 (AU)
Title: Multilayer biodegradable thin film and preparation method thereof
Inventor: CHEN CHANGPING
IPC: C08L29/04
Filed: 2020-08-07
Abstract: The present invention discloses a multilayer biodegradable thin film composed of a 
surface layer, a core layer and an inner layer and a preparation method thereof, wherein 
the core layer comprises 100 parts of PVA, 60-100 parts of starch, 30-42 parts of a 
plasticizer, 0.4-1.0 part of a chemical modifier and 0.2-0.6 parts of a chain extender; the 
surface layer and the inner layer comprise 100 parts of PBAT, 30-50 parts of PHA and 
1-3 parts of a lubricant. According to the multilayer biodegradable thin film prepared by 
the present invention, a thin film with good water resistance is attached to each of the 
inside and outside of a PVA/starch thin film with good airtightness, and an obtained thin 
film has good airtightness and waterproofness and is completely biodegradable, 
environmentally friendly and especially suitable for food packaging.
Patent AU-2020231506-A1 (AU)
Title: Methods for the treatment of perimenopause and menopause
Inventor: LOYA CARLOS
IPC: A61K31/575
Filed: 2020-03-04
Abstract: The invention relates to methods of treating the symptoms of perimenopause or menopause using positive allosteric modulators γ-aminobutyric acid type A (GABA-A PAMs) receptor, including 3α-hydroxy-3β-methoxymethyl-21-(1'-imidazolyl)-5α-pregnan-20-one and salts thereof.
Patent AU-2020253392-A1 (AU)
Title: Systems and methods for non-continuous deposition of a component
Inventor: STEINBERG ALEXANDER GABRIEL
IPC: B22F3/00
Filed: 2020-04-01
Abstract: A method of manufacturing using an additive manufacturing process includes providing a deposition system, the deposition system (12) configured to provide a plurality of cells (40) to form a blank (70) of a part, depositing a first layer of the blank (70), the first layer comprising a first deposited cell (40), a second deposited cell (40) spaced apart from the first deposited cell (40), and a third deposited cell (40) spaced apart from the first deposited cell (40) and the second deposited cell (40), and depositing a second layer of the part on the first layer, the second layer comprising a fourth deposited cell (40), a fifth deposited cell (40) spaced apart from the fourth deposited cell (40), and a sixth deposited cell (40) spaced apart from the fourth deposited cell (40) and the fifth deposited cell (40). Each of the first layer and the second layer are formed using non-continuous deposition to form the blank (70).
Patent AU-2020266347-A1 (AU)
Title: Ionic channel modulation as a method for treating tumors through inflammasome activation
Inventor: HILL MONGABURE MARCELO
IPC: A61P35/00
Filed: 2020-04-28
Abstract: The invention presents use of ion channel modulator to manipulate expression of the Tmem176b gene, also known as TORID (TOlerance Related and Induce D), to treat tumors.
Patent AU-2020270394-A1 (AU)
Title: Systems and methods for making thermoplastic products and compositions
Inventor: WILKINS VINCE
IPC: E01F9/50
Filed: 2020-05-01
Abstract: Systems and methods to produce thermoplastic products in a process are described herein. In some cases, the systems and methods may eliminate contact between the product and a heat transfer fluid. The thermoplastic compositions can be useful for roadway markings. In some examples, a formed thermoplastic product is discharged by a product formation apparatus onto a temperature controlled transporter, cooled, and cut to a desired product dimension.
Patent AU-2020283935-A1 (AU)
Title: Transcriptional relay system
Inventor: CHAN LEON YEN-LEE
IPC: C12N15/67
Filed: 2020-05-27
Abstract: Described herein are transcriptional relay systems useful for reducing background signal in protein expression and reporter assays. These systems utilize a nucleic acid system wherein a promoter sequence controls expression of a synthetic transcription factor that activates transcription of a reporter molecule.
Patent AU-2020296866-A1 (AU)
Title: Methods and devices for endovascular ablation of a splanchnic nerve
Inventor: BAPNA ANISHA
IPC: A61B18/14
Filed: 2020-06-22
Abstract: Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.
Patent AU-2020310897-A1 (AU)
Title: Indanes as PD-L1 inhibitors
Inventor: MALATHONG VIENGKHAM
IPC: A61K31/4412
Filed: 2020-07-09
Abstract: Compounds represented by Formula (I) or (II) are provided herein, or a pharmaceutically acceptable salt, or a prodrug or bioisostere thereof; wherein R
Patent AU-2020328026-A1 (AU)
Title: Uracil dermal pharmaceutical formulation
Inventor: ISAACMAN STEVEN
IPC: C07D239/54
Filed: 2020-08-13
Abstract: The present disclosure provides a topical pharmaceutical formulation comprising uracil and a penetration enhancer, method of administration the same. Also provided is a method of treating or preventing dermatoses associated with the administration of a 5- fluorouracil or a precursor or prodrug thereof, such as capecitabine. the penetration enhancer is selected from the group consisting of dimethyl isosorbide, isopropyl myristate, isopropyl palmitate, octyldodecanol, oleic acid, oleyl alcohol, polyoxylglyce rides, pyrrolidone, thymol, tricaprylin, triolein, myristic acid, medium chain triglycerides, linoleic acid, lauric acid, glycofurol, glyceryl monooleate, ethyl oleate, dimethyl sulfoxide, dibutyl sebacate, and mixtures thereof.
Patent AU-2020368526-A1 (AU)
Title: Regenerating functional neurons for treatment of neurological disorders
Inventor: CHEN GONG
IPC: C12N15/85
Filed: 2020-10-16
Abstract: This document provides methods and materials involved in treating mammals having a neurological disorder in the brain (e.g., Alzheimer's disease). For example, methods and materials for administering a composition including exogenous nucleic acid encoding a NeuroD1 polypeptide to a mammal having a neurological disorder in the brain are provided.
Patent AU-2020381574-A1 (AU)
Title: Method of clothed treatment during radiation therapy and garment for same
Inventor: SINTAY BENJAMIN JEREMIAH
IPC: A41D13/12
Filed: 2020-11-16
Abstract: The presently disclosed subject matter relates generally to a treatment garment for use in clothed radiation treatment and diagnosis procedures, and methods of using the garment.
Patent AU-2020405407-A1 (AU)
Title: System and method for obtaining profile of eye lens capsule
Inventor: MISSEL PAUL
IPC: G06T7/50
Filed: 2020-06-18
Abstract: A system includes a controller with at least one processor and at least one non-transitory, tangible memory on which instructions are recorded for executing a method for obtaining a profile of a lens capsule of an eye. The profile is represented by respective central surfaces and respective equatorial surfaces separated at respective transition points. The controller is configured to obtain imaging data for a portion of the lens capsule visible through a pupil of the eye. The imaging data is transformed to an adjusted frame of reference and fitted to the respective central surfaces in a predefined central region of the lens capsule. The profile is obtained based on a set of fitting parameters for the respective central and equatorial surfaces. The respective central surfaces and respective equatorial surfaces may be represented as elliptical cones and skewed parabolas, respectively.
Patent AU-2021200030-A1 (AU)
Title: Devices and methods for anchoring a sheath in a tissue cavity
Inventor: FONG KENTON D
IPC: A61F2/04
Filed: 2021-01-05
Abstract: DEVICES AND METHODS FOR ANCHORING A SHEATH IN A TISSUE 
CAVITY 
ABSTRACT 
According to some embodiments of the invention, an anchoring system includes a sleeve 
having an inner surface defining a first lumen, a first annular sealing mechanism disposed at a 
proximal end of the sleeve, and a second annular sealing mechanism disposed at a distal end of 
the sleeve. The anchoring system further includes a pressure tube in fluid connection with an 
outer surface of the sleeve, a sheath in mechanical connection with the sleeve, the sheath 
forming a second lumen, the second lumen being in fluid connection with the first lumen, and 
open-cell foam disposed on the outer surface of the sleeve. Application of negative pressure to 
the pressure tube causes a seal to form between the first and second annular sealing mechanisms 
and an inner surface of a tissue cavity. Application of negative pressure to the pressure tube also 
creates a frictional force that resists displacement of the sleeve.
Patent AU-2021202104-A1 (AU)
Title: Vibration generator and apparatus for engraving an image
Inventor: HOSHIYAMA YUICHI
IPC: B06B1/04
Filed: 2021-04-06
Abstract: OF THE DISCLOSURE 
The present invention provides a vibration generator capable of 
accurately adapting to fine vibration. The vibration generator 19 has a stationary 
5 permanent magnet 47, a yoke 49 for the permanent magnet 47, a coil 51 fixed to 
the yoke 49, four springs 53 provided to the yoke 49, and a movable piece 55 
supported with the yoke 49 through the four springs 53. The end portions 55a of 
the movable piece 55 are arranged between the respective two pairs of the 
projections 49h, 49i, 49j and 49k with first gaps tI. The central portion 55b of 
10 the movable piece 55 is arranged in the through-hole 51a with the second gaps t2, 
the second gaps t2 having a size to allow oscillation, which is regulated by the 
first gaps tI, of the central portion 55b of the movable piece 55.
Patent AU-2021209221-A1 (AU)
Title: Detecting mutations and ploidy in chromosomal segments
Inventor: BABIARZ JOSHUA
IPC: C12Q1/68
Filed: 2021-07-27
Abstract: The invention provides methods, systems, and computer readable 
medium for detecting ploidy of chromosome segments or entire 
chromosomes, for detecting single nucleotide variants and for detecting 
both ploidy of chromosome segments and single nucleotide variants . In 
some aspects, the invention provides methods, systems, and computer 
readable medium for detecting cancer or a chromosomal abnormality in 
a gestating fetus.
Patent AU-2021209953-A1 (AU)
Title: Prodrug for the treatment of disease and injury of oxidative stress
Inventor: WALL G MICHAEL
IPC: A61K31/198
Filed: 2021-01-23
Abstract: The present invention includes a method for using diNACA as a prodrug to deliver diNACA, NACA and NAC to a mammal for therapeutic purposes to prevent or treat diseases or disorders involving oxidative stress. The method includes any disease that involves the therapeutic use of NACA or NAC as a therapeutic agent. Also, compositions and methods for the prevention, reduction or treatment of corneal endothelial cell loss in a patient that comprise providing the patient with an amount of at least one, alone or in combination, of N-acetylcysteine amide (NACA) or (2R,2R')-3,3'-disulfanediyl bis(2- acetamidopropanamide) (diNACA) (diNACA) to prevent or reduce the corneal endothelial cell loss or to prevent or treat presbyopia. DiNACA can be used to prevent or treat cataracts.
Patent AU-2021215159-A1 (AU)
Title: Composition in powder form comprising iron-casein complexes and compounds sensitive to oxidation
Inventor: BEDARD MATTHIEU
IPC: A23L33/12
Filed: 2021-08-11
Abstract: The present invention relates to a composition comprising compounds sensitive to oxidation and at 
least one iron-casein protein complex, wherein the complex is a non-micellar iron-casein complex 
comprising exogenous iron, casein and exogenous orthophosphorus. Such iron-casein complex 
advantageously does not cause significant oxidation of sensitive compounds such as LC-PUFAs, 
vitamins and polyphenols.
Patent AU-2021221792-A1 (AU)
Title: Improved Trailer Chassis Assembly
Inventor: REID GLEN
IPC: B62D63/06
Filed: 2021-08-25
Abstract: A trailer chassis assembly comprising: an extruded chassis rail component, the component comprising a 
wall surface defining an interior space and an opening in the wall surface extending through the wall 
surface to the interior channel; a cross member component; a connector component comprising: a first 
region adapted to engage with the interior space of the chassis rail component, and a second region 
adapted to engage with the cross member component.
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Figure 6 
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Figure 7 
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Patent AU-2021225947-A1 (AU)
Title: Crystalline bis-miprocin fumarate
Inventor: CHADEAYNE ANDREW R
IPC: C07D487/04
Filed: 2021-02-26
Abstract: The disclosure relates to crystalline forms of bis(4-hydroxy-
Patent AU-2021227930-A1 (AU)
Title: Systems and methods for determining viruses such as coronaviruses
Inventor: CHAIT ARNON
IPC: B01L3/00
Filed: 2021-02-26
Abstract: Certain aspects of the present disclosure generally relate to systems and methods for determining viruses. For instance, some aspects are directed to systems and methods for determining viruses using a partitioning system. Within the partitioning system, the virus may partition into one or more phases. In some cases, a virus-binding moiety facilitates partitioning of the virus. The phases may be assayed to determine the virus based on, e.g., quantitative or qualitative assessments of the distribution of virus-binding and/or signaling moieties. The virus -binding moiety may be attached to particles that may form a complex around a virus. The complex may be detectable without a signaling moiety (e.g., as a color change) in some embodiments. In some cases, more than one virus may be determined. For example, a virus -binding moiety may substantially alter the partitioning behavior of one virus or complex, relative to another, by being selective for the first virus.
Patent AU-2021241377-A1 (AU)
Title: Ventilating firestop
Inventor: JENSEN GEIR
IPC: F16J15/06
Filed: 2021-03-24
Abstract: The invention relates to a ventilating firestop (10), comprising a load-bearing mesh(12) fitted with an intumescent (14), wherein the mesh (12) is malleable to a completely or partially confined volume (22), and the intumescent (14) applied to the mesh (12) forms a stripe pattern of intumescent spaced apart and with ventilating openings (30) between the stripes. At least the intumescent (14) in a plane which is exposed by fire forms a fine mesh and rapidly expandable stripe pattern which, during the fire attack phase, seals the openings (30) and forms a fire-insulating shield (40), and the intumescent (14) located separately from the shield (40), after formation of the shield (40), is expandable to subsequently fills up the remaining volume (22) in the firestop (10).
Patent AU-2021256428-A1 (AU)
Title: Integration of large adenovirus payloads
Inventor: LIEBER ANDRE
IPC: C12N7/00
Filed: 2021-04-12
Abstract: The current disclosure provides recombinant adenoviral vectors and adenoviral genomes that can accommodate or that contain a large transposon payload, for instance a transposon payload of up to 40 kb. The adenoviral vectors and genomes can deliver the large transposon payload into a target genome, for instance for gene therapy.
Patent AU-2021260168-A1 (AU)
Title: Training vest apparatuses of multi-resistance for sports performance, military training, flotation device and for leisure activities
Inventor: BASSOO NAIPAUL
IPC: A63B21/065
Filed: 2021-04-20
Abstract: There is disclosed herein a training vest apparatus including a body portion of the apparatus, one or more resistance elements attachable to the body portion. The vest is adapted for movement between an assembled closed configuration wherein one or more of the resistance elements is attached to the body and a disassembled open configuration. The apparatus includes fasteners and adjustable working straps to fit the body portion of a user and to correct the user posture. The resistance elements for sports performance comprises of one or more sling bands, wherein one or more of the sling bands comprises of a limb strap. The apparatus includes a removable or fixed hydration pack, molle for a military appearance and reinforcement for attachable objects. Removable weights such as mental plates and filler weights can be added for weight training with a transition to minimal to no weight to use as a flotation device.
Patent AU-2021266564-A1 (AU)
Title: Centrifugal compressor and method of operating the centrifugal compressor to produce a uniform inlet flow of process gas
Inventor: QUERCIA MARCO
IPC: F04D29/42
Filed: 2021-04-29
Abstract: The centrifugal compressor (100) has a housing (110) with two or more compressor inlets (120) for process gas to be compressed; an impeller (130) is located inside the housing (110) so to receive an inlet flow of process gas from the two compressor inlets (120) through a plenum chamber (115) and increases gas pressure as process gas flows in the impeller (130); thanks to the two or more inlets (120), uniformity of flow at the inlets (120) may be achieved through short collector pipes (121) fluidly connected upstream of the inlets (120); piping of a compressor system including such compressor is made easy as it is subject to fewer constraints.
Patent AU-2021290232-A1 (AU)
Title: Apparatus and method for combinatorial hypermap based data representations and operations
Inventor: MAJUMDAR ARUN
IPC: G06N3/02
Filed: 2021-12-21
Abstract: A method and apparatus for representing and comparing graph data in circuitry, comprising: receiving 
input graph data; performing a graph structure match search between the input graph data and other 
graph data in a graph database by: representing the input graph data as a generalized combinatorial 
hypermap; bijectively representing a sub-map of the generalized combinatorial hypermap using a plurality 
of arrays of numbers including an array of fixed point free involutions; bijectively mapping the plurality of 
arrays of numbers to a Godel number; and comparing the sub-map of the generalized combinatorial 
hypermap with another sub-map of the other graph data in the graph database by comparing the Godel 
number representing the sub-map to a Godel number representing the another sub-map, thereby 
improving computational efficiency for determining isomorphism between sub-maps relative to methods 
that determine isomorphism by traversing and comparing nodes, thereby allowing to efficiently perform 
composition and unification of the graph data; compiling a database of compositional patterns to include 
topologies of sub-maps of the generalized combinatorial hypermap that are determined to be isomorphic 
with other sub-maps, the sub-map of the generalized combinatorial hypermap being included in the sub
maps of the generalized combinatorial hypermap, and the another sub-map of the other graph data in the 
graph database being included in the other sub-maps; and performing unification of respective sub-maps 
of the generalized combinatorial hypermap when the respective sub-maps of the generalized combinatorial 
hypermap are determined to be isomorphic with sub-maps of the other graph data in the graph database.