baber/WOPTO huggingface dataset:
Patent ES-8106734-A1 (ES)
Title: 3-Vinyl-cephalosporins
IPC: A61P31/04
Filed: 1980-09-22
Abstract: Novel 3-vinyl-cephalosporins of the formula < IMAGE > (I) in which n is 0 or 1, R1 is hydrogen, a radical of the formula < IMAGE > (II) [in which R4 is hydrogen or a protective radical and R5 is hydrogen, alkyl, vinyl or cyanomethyl or is a protective radical], or a protective radical, and R2 is hydrogen, a protective radical or an enzymatically removable radical, or R1 is hydrogen or an acyl radical which may carry various substituents and R2 is hydrogen or a protective radical, and R3 is a radical of the general formula R'3-SO2-O- or R''3-CO-O-, in which R'3 is alkyl, trifluoromethyl, trichloromethyl or phenyl which is substituted by a halogen atom or by an alkyl or nitro radical, and R''3 is defined like R'3 or represents methyl which is substituted by acyl or alkoxycarbonyl, or represents ethyl or propyl substituted in the 2-position by acyl or alkoxycarbonyl. These compounds are useful as intermediates for the preparation of antibiotic 3-thiovinyl-cephalosporins.
Patent ES-8205428-A1 (ES)
Title: Method for the production of human leucozyte interferon.
IPC: C12P21/02
Filed: 1981-02-10
Abstract: Recombinant DNA technology is utilized in the production of interferon and there is provided a microbiologically produced polypeptide, all or part of which comprises the amino acid sequence of human interferon, especially leukocyte ( alpha ) interferon a cDNA which codes for such a polypeptide a plasmid especially plasmid pBR 322, which comprises the cDNA and a microorganism, for example, E. Scherichia coli, especially E.coliK12 or E.coliX 1776, which comprises the genetic information required for the production of such a polypeptide. The cDNA is prepared using mRNA obtained from human leukocytes and/or cells of a human lymphoblastoid cell line.
Patent ES-8203900-A1 (ES)
Title: 7,8,9,10-Tetrahydrofuro(3,2-e)pyrido(4,3-b)indoles, process for their preparation and their use in medicaments, and their preparation.
IPC: C07D491/14
Filed: 1981-06-12
Abstract: The 7,8,9,10-tetrahydrofuro[3,2-e]pyrido-[4,3-b]indoles are used in medicaments, especially medicaments for influencing the central nervous system.
Patent ES-8204725-A1 (ES)
Title: N-heteroarylalkylene diamines, process for their preparation and their use.
IPC: C07D231/52
Filed: 1981-06-17
Abstract: The present invention provides aryloxypropanolamines of the general formula: < IMAGE > (I) wherein R1, R2, R3 and R4, which may be the same or different, are hydrogen or halogen atoms or lower alkyl, cyano, carboxamido, hydroxyl, lower acyloxy, lower alkoxy, lower alkenyloxy or aryl lower alkoxy radicals, R5 and R6, which may be the same or different, are hydrogen atoms or lower alkyl radicals, X is a straight or branched alkylene chain containing 2 to 6 carbon atoms, A is a mono-, bi- or tricyclic heteroaromatic or hydroheteroaromatic radical or, when at least one of the symbols R1, R2, R3 and R4 is other than a hydrogen atom, may also be a phenyl radical, with the proviso that when A is a uracil-6-yl radical, the 5-position of the uracil moiety does not contain a hydrogen atom, R7, R8, R9, R10 and R11, which may be the same or different, are mono- or divalent substituents selected from hydrogen, halogen, nitro, hydroxylamino, amino, lower acylamino, lower alkylamino, di-(lower alkyl)-amino, hydroxyethylamino, di-(hydroxyethyl)-amino, hydroxyl, lower alkoxy, allyloxy, methoxy lower alkoxy, cyano, carboxamido, carboxy, lower alkoxycarbonyl, hydroxymethyl, lower alkoxymethyl, halomethyl, aminomethyl, lower acylaminomethyl, di-(lower alkyl)-aminomethyl, pyrrolidinomethyl, piperidinomethyl, di-(hydroxyethyl)-aminomethyl, morpholinomethyl, piperazinomethyl, 4-lower acylpiperazinomethyl, 4-lower alkylpiperazinomethyl, lower alkyl, lower alkenyl, 2-cyanoethyl, 2-(lower alkoxycarbonyl)-ethyl, 2-carboxyethyl, 2-hydroxyethyl, phenyl lower alkyl and phenyl, the phenyl radicals being optionally substituted with 1 or 2 hydroxyl or methoxy radicals, or from oxygen or sulphur the optically-active forms and the racemic mixtures thereof, and the pharmacologically compatible salts thereof. The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them.
Patent ES-8300705-A1 (ES)
Title: Method for the manufacture of 3-picoline.
IPC: C07D213/10
Filed: 1982-01-08
Abstract: Process for the production of 3-picoline wherein a first educt, consisting of acetaldehyde and/or at least one acetaldehydeacetal and/or crotonaldehyde, is reacted with a second educt, consisting of formaldehyde and/or at least one formaldehydeacetal and/or hexamethylenetetramine, in a liquid, aqueous phase at a temperature of 180 DEG to 280 DEG C. in a closed vessel. The reaction is conducted in the presence of ammonia and/or ammonium ions. The reaction is also conducted in the presence of at least one water-soluble alkali metal salt of an inorganic and/or organic acid or acids which provides an anion or anions of an inorganic and/or organic acid or acids, which at 20 DEG C. have an acid dissociation constant of 106 to 10-12.
Patent ES-8306958-A1 (ES)
Title: Apparatus for treating back ailments.
IPC: A61H1/02
Filed: 1982-08-20
Abstract: An apparatus for treating back ailments comprises a support means (10) for supporting a patient belts (19, 26) for encircling the chest and pelvis respectively of the patient tension or pulling means (17) connected to the belt (26) for the pelvis or chest of the patient and a readily moveable carrier means (14) for supporting the pelvis or chest of the patient. The readily moveable carrier means (14) is arranged to execute, simultaneously with or independently of a translatory movement, rotary movement in the horizontal plane and/or a skewing or distorting movement about an axis in the longitudinal of the carrier means (14), in accordance with a programme previously decided for the patient. Rotary movement is arranged to take place about a vertical axis between the carrier means (14) and a means (13) for supporting the small of the back, preferably located at the second vertebra of the patient, counted from the pelvis region. The means for supporting the small of the back is provided with a pressure sensing means (40) and is arranged to be controlled vertically in dependence upon the pressure sensed by the pressure sensing means (40).
Patent ES-8402873-A1 (ES)
Title: Immobilization of the sucrose mutase in whole cells of Protaminobacter Rubrum.
IPC: C12N11/16
Filed: 1982-10-25
Abstract: Sucrose mutase in whole cells of Protaminobacter rubrum #l is immobilized by contacting the cells with tannic acid, polyethylenimine, and an adduct of glutaraldehyde and an epihalohydrin/polyamine copolymer. The resultant reaction product has improved sucrose mutase activity and physical characteristics for use in a packed-bed reactor to convert sucrose to palatinose.
Patent ES-8400473-A1 (ES)
Title: Inorganic pigment prodn. from powder mixts. - by calcination after compaction into moulded shapes
IPC: C09C3/00
Filed: 1982-12-17
Abstract: Prodn. of inorganic pigments is effected by calcination of the starting materials in the form of a powder mixt. The novel feature comprises compressing the powder mixt. into moulded shapes before calcination. The powder mixt. may be mixed with water and/or a binder and compacted, e.g. using a granulating roller, pelletising press or briquetting machine. The resulting shapes (e.g. bars or plates) pref. have a high surface area and low thickness (esp. 1.5 cm. or less). In the case of oxidn.-sensitive pigments, they can be coat with a thin layer of inert material. The shapes can be supplied continuously to the calcination furnace. Compaction of the powder improves heat transfer, thus reducing calcination times and energy consumption, simplifies handling, and eliminates the need for crucibles, etc.
Patent ES-8406776-A1 (ES)
Title: Non cross-linkable electrically conductive moulding masses based on thermoplastic plastics and soot.
IPC: H01B1/24
Filed: 1983-12-07
Abstract: 1. A non cross-linkable, electrically conductive and calenderable moulding massa based on thermoplastic plastic, inorganic fillers and soot consisting of A) 15 to 75 parts by weight of a chlorinated polyethylene having a mean molecular mass of 10,000 to 100,000 and a chlorine content of 20 to 50 % by weight, relative to the weight of the chlorinated polyethylene, B) 10 to 20 parts by weight of polyethylene having a density of 0,940 to 0,965 g/cm**3 and a melt index of 0,1 to 60 g/10 minutes at 190 degrees C and 49,03325 N (5 kp) of load, and/or polypropylene having a density of 0,900 to 0,915 g/cm**3 and a melt index of 0,5 to 30 g/10 minutes at 190 degrees C and 49,03325 N (5 kp) of load, C) 10 to 70 parts by weight of a filler selected from the group consisting of aluminium hydroxide, barium sulfate, calcium carbonate, magnesium silicate and titanum dioxide having a means particle diameter of 0,5 to 15 mu m, D) 10 to 25 part by weight of soot having a specific surface of 100 to 400 m**2/g and a mean particle diameter of 10 to 80 mu m, or 4 to 10 parts by weight of soot having a specific surface of 700 to 1,500 m**2/g and a mean particle diameter of 10 to 80 mu m, E) 0,5 to 2 parts by weight of the heat stabilizer, F) 0,1 to 0,5 part by weight of the lubricant, and G) 0,5 to 5 parts by weight of a vinyl chloride polymer, the sum of the components A), B) and C) being 100 parts by weight.
Patent ES-8501138-A1 (ES)
Title: Gage block management system
IPC: G06F15/02
Filed: 1984-01-12
Abstract: A gage block case includes a plurality of gage blocks mounted within the case, each gage block having opposed gage surfaces with a nominal dimension therebetween and a known deviation from the nominal dimension. Sensors associated with each gage block sense the removal of each gage block from the case. A signal generator provides a distinct signal corresponding to which gage block is removed from the case. A memory stores the known deviation of each gage block within the case. A control unit responsive to the signal generator addresses and retrieves from the memory the known deviation for each gage block which is removed from the case, combines the known deviation with the deviations of previously removed gage blocks and outputs the total deviation to a display device. In a second embodiment, the control unit selects and indicates which gage blocks are to be removed from the case to form a specified stack height input to the control unit.
Patent ES-8507024-A1 (ES)
Title: Manoeuvring apparatus for use in a foundry plant.
IPC: B22D47/02
Filed: 1984-04-17
Abstract: In an automatic foundry plant where automatic core feeding and exchange of core masks (48) as well as pattern plates are required, both a simplification of the plant and a rationalization of the operation are obtained by the use of a manoeuvring apparatus with a gripper (26), which is both rotatable and slidable in at least two directions and which has elements of engagement (33, 34, 36) arranged to cooperate with corresponding engagement elements (47) on the parts to be manoeuvred all the latter elements are uniform and placed in a specific manner so that the same manoeuvring apparatus can handle all the parts which are relevant as manoeuvring objects.
Patent ES-8502296-A1 (ES)
Title: Monophase mains current converter and its control device
IPC: H02M7/155
Filed: 1984-05-04
Abstract: Monophase mains current converter 2 for stabilising a DC output voltage during a highly variable input voltage Ue by using a power transformer 1 provided with taps 1.1 to 1.4 characterised by four half-bridges 2.1 to 2.4 connected across the four taps of the transformer the tap 1.1 for the zero common or reference potential is applied to the bridge 2.1 which is not controllable, the other three taps 1.2 to 1.4 are provided for a constant output voltage UeNom, UeNom + 30 % and UeNom - 30%.
Patent ES-8506078-A1 (ES)
Title: Stabilized bleach-sensitive dyes in automatic dishwasher detergent compositions.
IPC: C11D3/40
Filed: 1984-07-27
Abstract: A method for stabilizing automatic dishwasher detergents containing bleach-sensitive dyes against decolorization by the bleaching agents of the compositions. The detergent powders comprise about 5-70% of a builder, 1-15% of a nonionic surfactant, 1-20% of a silicate, 0-60% of a filler, 0.001-0.1% of a bleach-sensitive dye, water and a bleaching agent. Prior to the addition of bleaching agent, the composition is pre-conditioned by contact with a flow of air. The resultant powder has a color that remains essentially unchanged even after storage for two months at elevated temperatures.
Patent ES-8506857-A1 (ES)
Title: Built-up piston
IPC: F02F3/22
Filed: 1984-10-24
Abstract: A built-up piston in which the piston top (11) and piston bottom part (13) are clamped together by two necked-down bolts (15) by means of nuts (16). The nuts include an extension (21) having an external thread (22), by means of which they are screwed into the piston bottom part (13). An oil scraper ring (14) is arranged between piston top (11) and piston bottom part (13) so that leakage oil out of the cooling oil channel of the piston is conducted back into the crankcase by way of the oil discharge channels of the annular groove of the oil scraper ring.
Patent ES-8507621-A1 (ES)
Title: Method of working up heavy metal-containing residues from the chemical industry
IPC: F23G5/08
Filed: 1984-11-12
Abstract: There is disclosed a method for processing heavy-metal-containing residues from the chemical industry. For an economical and at the same time ecologically safe processing of the heavy-metal-containing residues, the heavy-metal-containing residues are introduced into a primary-gas reaction zone of a shaft gasifier containing at least one solid bed of carbon-containing material. Slag-forming substances are introduced together with the charge substances and/or together with the solid-bed formers to absorb and set the heavy metals. The lower zone of the solid bed is maintained at a temperature above the slag and ash melting temperatures. The viscosity of the slag is less than 100 poise.
Patent ES-8606845-A1 (ES)
Title: Alpha-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides.
IPC: C07C239/00
Filed: 1984-11-15
Abstract: Hydrocarboxylation of enamides with CO and a compound ROH yields amido acids or amido esters, which can be hydrolyzed to alpha -amino acids. This process avoids the use of HCN in the production of amino acids.
Patent ES-8605962-A1 (ES)
Title: Microwave heating package.
IPC: B65D81/34
Filed: 1985-02-13
Abstract: A novel cover (38, 40, 48) arrangement is described for use with foodstuff holding pans (30) to be heated in a microwave oven. The cover is one which in terms of microwave energy, does not transmit reflected energy. Thus, the cover acts in a manner analogous with non-reflecting coatings in optics and permits passage of the microwave radiation into the container holding the foodstuff (18), while substantially preventing escape of microwave radiation reflected from the foodstuff surface and container bottom (32). In this manner the microwave energy is retained and concentrated within the container, resulting in more efficient and uniform heating of the foodstuff. The novel cover is particularly valuable when used with aluminium foil pans, which without the cover of this invention seriously reflect microwave radiation.
Patent ES-8606131-A1 (ES)
Title: Printing unit.
IPC: B41K3/06
Filed: 1985-02-20
Abstract: A printing mechanism (10) is descirbed which comprises a plurality of setting wheels (16) rotatably mounted on a common axis. With these settings wheels (16) type carriers (20) carrying printing types in one peripheral region and indicator types in another peripheral region are in a drive connection. A setting shaft (42) carrying an actuating knob (48) and adapted to be brought into a drive connection with each of the setting wheels (16) is arranged rotatably and axially displaceably. Stop means limit the rotation angle of the setting wheels (16). The actuating knob (48) and the setting shaft (42) are in connection with each other via a slip coupling.
Patent ES-8800039-A1 (ES)
Title: Pharmaceutical composition.
IPC: A61K47/04
Filed: 1985-05-22
Abstract: A pharmaceutical composition comprising a freely flowable powder, the powder comprising a porous, high absorption silica or silicate having absorbed therein at least 10% by volume of a liquid, pharmaceutically active composition, based on the weight of powder plus liquid, provided that when the liquid pharmaceutically active composition is a corticoid solution the silica or silicate has a mean particle size of at least 10 mu m in diameter.
Patent ES-8604165-A1 (ES)
Title: Benzimidazoles, their preparation, and medicaments containing these compounds.
IPC: A61P9/12
Filed: 1985-06-13
Abstract: Benzimidazoles of the formula < IMAGE > in which R1 denotes a hydroxyl, alkoxy, phenylalkoxy, cyanoalkoxy, alkylsulphenyl, alkylsulphinyl, alkylsulphonyl, aminosulphonyl, alkylaminosulphonyl, dialkylaminosulphonyl, alkylsulphoximino, alkenyloxy or alkynyloxy group, R2 denotes a hydrogen atom, a hydroxyl, alkoxy, phenylalkoxy, amino, alkylamino or dialkylamino group, R3 denotes a hydrogen atom or an alkoxy group and R4 denotes a hydrogen or halogen atom, or a cyano, nitro, amino, carboxyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, aminocarbonylamino, alkylaminocarbonylamino or dialkylaminocarbonylamino group, their tautomers and their acid addition salts have useful pharmacological properties, in particular an effect on the blood pressure and on the contractility of the heart muscle. The novel compounds can be prepared by processes known for analogous compounds.
Patent ES-8607322-A1 (ES)
Title: Novel preparation of cephalosporin compound
IPC: C07D501/00
Filed: 1985-10-02
Abstract: PURPOSE:To produce the titled compound useful as an antibacterial agent, by a novel process, by condensing a novel substituted hydroxyiminoacetic acid compound with an amino cephem carboxylic acid compound. CONSTITUTION:The objective compound of formula IV can be prepared by condensing (Z)-2-aminothiazolyl-2-substituted-hydroxyiminoacetic acid compound of formula I (R<1> is H or lower alkyl n is 2 or 3) or its reactive derivative with (6R, 7R)-7-amino-3-cephem-4-carboxylic acid compound (salt) of formula II [when R<2> is acetoxy, etc., R<4> is (protected) carboxy, and when R<2> is group of formula III (Y is H or hydroxymethyl), R<4> is -COO<->], and when R<4> is protected carboxyl, removing the protecting group. The starting compound of formula I is novel, and can be produced e.g. by reacting the butyric acid derivative of formula V (R<6> is H, etc. X is halogen) with thiourea.
Patent ES-8700770-A1 (ES)
Title: Processing system for a gambling game.
IPC: G06Q50/00
Filed: 1985-10-25
Abstract: The system comprises a first self-contained and portable device (200) enabling the reading, erasing and inscription on the data medium (1), as well as the verification of the result after the drawing a second fixed device associated with a computer of a betting management center enabling the reading of data written on the data medium (1) by the first device (200), transmission to the management center for recording the read data of the bets, indication and optionally collection of sums of money to be cashed as stake and the inscription on the data medium (1) in an area to which the first device (200) has no access of indications relative to bet data.
Patent ES-8704905-A1 (ES)
Title: Cyclopenta[d]pyrimidine derivatives, their preparation and use.
IPC: C07D239/70
Filed: 1986-03-07
Abstract: Compounds of formula (I): < IMAGE > (I) (wherein R1 and R2 are hydroxy, alkoxy, aryloxy or acyloxy or R2 is hydrogen, R3 is hydrogen or alkyl and R4 and R5 are hydrogen or various organic substituents) have valuable antidepressant activity and may be used in the treatment of mental depression.
Patent ES-8800261-A1 (ES)
Title: Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them.
IPC: C07J41/00
Filed: 1986-04-03
Abstract: The invention refers to compounds having anti-inflammatory activity characterized by the formula < IMAGE > or a stereoisomeric component thereof, in which formula X1 represents a hydrogen, chlorine, bromine or fluorine atom X2 represents a hydrogen, chlorine, bromine or fluorine atom R1 represents a beta -hydroxy group, a beta -chlorine atom or an oxo group R2 represents a hydrogen atom, a methylene group or an alpha - or beta -methyl group R3 represents a hydrogen atom or an acyl group of 1 through 8 carbon atoms R4 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group R5 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group Y represents either CR7R8, O, S or NR9, where R7, R8 and R9 are selected from hydrogen or from straight or branched hydrocarbon chains having 1-8 carbon atoms or from a phenyl group. R6 represents a hydrogen a methyl group a phenyl or an alkenyl or cycloalkylene group optionally substituted by alkyl, nitro, carboxy, alkoxy, halogen, cyano, carbalkoxy and trifluoromethyl group(s) a (C1-C5) alkyl group substituted by at least one halogen atom a saturated or unsaturated carbocyclic or heterocyclic (O, S, N) ring system containing 3-10 atoms in the ring system a C1 alkyl group substituted by either one or two alicyclic or aromatic 3,4,5 or 6-numbered ring system(s) or one, two or three straight or branched alkyl or alkenyl group(s) of 1 through 18 carbon atoms and represents a single or double bond. The invention also refers to a process and intermediates for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment of inflammatory conditions.
Patent ES-8703747-A1 (ES)
Title: Process for purifying an industrial or a flue gas.
IPC: B01D53/34
Filed: 1986-05-19
Abstract: In purifying gas wash waters containing cyanide with formaldehyde, the exact dosing of formaldehyde presents a problem, especially with strongly fluctuating cyanide contents. By continuous potentiometric measurement in a side stream which is regulated to a pH of 7 to 10, while the pH of the main stream remains unchanged, the formaldehyde can be adjusted safely to any cyanide content.
Patent ES-8707269-A1 (ES)
Title: Bismaleimide compositions.
IPC: C08F222/40
Filed: 1986-06-06
Abstract: The invention relates to a composition comprising (A) 64-4 parts by wt. of a bismaleimide compound, or an isomaleimide isomer thereof, a maleimide-amide compound or an isomaleimide isomer thereof and maleic anhydride compound, (B) 7-77 parts by wt. of one or more ethylenically unsaturated compounds containing 5-50 C-atoms and is characterized in that the composition further comprises (C) 3-60 parts by wt. of one or more compounds from the group of hydroxy-alkylacrylates or amino-alkylacrylates, (D) 1-20 parts by wt. of one or more terminally functional polymers as flexibilizer, with the proviso that the sum, of parts of compounds A, B, C and D amounts to 100.
Patent IE-914497-A1 (IE)
Title: Expression systems
IPC: C12P21/00
Filed: 1991-12-20
Abstract: Expression systems which comprise a mammalian host, such as erythroid cells, transformed with a vector which comprises a promoter, a DNA sequence which codes for a desired polypeptide and a dominant control region. The vectors and methods for preparing polypeptides using the expression systems are also described. In a preferred embodiment, the vector contains cDNA for the desired polypeptide and a sequence which is capable of stabilising mRNA produced from the cDNA. The expression systems are particularly efficient and are capable of secreting the desired polypeptide.