baber/WOPTO huggingface dataset:
Patent RU-2714116-C2 (RU)
Inventor: MESSNER Ekkekhard
IPC: C07K16/46
Filed: 2015-11-04
Granted: 2020-02-11
Abstract: FIELD: biotechnology. 
     SUBSTANCE: invention relates to biotechnology and immunology. Disclosed is a method of producing a human IgG Fc region containing a first variant polypeptide of the Fc region and a second variant polypeptide of the Fc region. First variant polypeptide of the Fc-region is derived from the first parent polypeptide of the Fc region of the IgG class, and the second variant polypeptide of the Fc-region comes from the second parent polypeptide of the Fc-region of the IgG class. First parent polypeptide is identical to the second parent polypeptide or differs from the second parent polypeptide. Mutations are introduced into parental polypeptides, including a combination of: T307H and N434H, where the numbering corresponds to the EU index by Kabat. As a result, the first variant polypeptide of the Fc region differs from the second variant polypeptide of the Fc region by one or more amino acid residues. If the first parent polypeptide is different from the second parent polypeptide, the first variant polypeptide differs from the second variant polypeptide by residues differing from those amino acid residues from which the first parent polypeptide differed from the second parent polypeptide. 
     EFFECT: obtained human IgG Fc-region has an affinity for the human neonatal Fc receptor, which is higher than that in the Fc region of the IgG class without mutations, which can be used in treating diseases requiring an extended retention time of the antibodies. 
     3 cl, 3 dwg, 4 tbl, 2 ex
Patent RU-2719941-C2 (RU)
Title: Тренировка мышц рта
Inventor: SAMA ANSHUL
IPC: A61N1/05
Filed: 2015-10-12
Granted: 2020-04-23
Abstract: Группа изобретений относится к медицинской технике, а именно к устройству для трансмукозальной нейромускулярной электростимуляции и способу тренировки мышц рта с помощью трансмукозальной нейромускулярной электростимуляции. Устройство содержит мундштук, электродное средство, связанное с мундштуком, и электрическую схему. Электрическая схема функционально связана с электродным средством. Мундштук содержит пару ответвлений с выступами. Ответвления соединены вместе на одном конце и расходятся друг от друга. Выступы продолжаются внутрь от ответвлений, при этом выступ содержит связанное с ним электродное средство. Электродное средство предназначено для увеличения тонуса мышц в состоянии покоя и тонуса мышц во время сна при применении электростимуляции через дорсальную поверхность языка по способу для увеличения тонуса мышц в состоянии покоя и тонуса мышц во время сна. Обеспечивается система лечения, применимая в активном состоянии пользователя, в которой электростимуляция мышц применяется для стимуляции мышц языка, неба, чувствительных нервов для повышения мышечной силы и восстановления тонуса путем тренировки мышц полости рта в состоянии бодрствования пациента для того, чтобы в течение плана лечения повысить мышечный тонус в состоянии покоя пользователя таким образом, что случаи апноэ становятся менее частыми, тем самым достигается устойчивое уменьшение неупорядоченных форм дыхания во время сна. 3 н. и 15 з.п. ф-лы, 11 ил.
Patent RU-2710984-C2 (RU)
Inventor: EMAMI ALI
IPC: G10L15/22
Filed: 2015-12-29
Granted: 2020-01-14
Abstract: Группа изобретений относится к цифровым помощникам. Технический результат – обеспечение возможности совершения задачи в цифровом помощнике без монитора. Для этого способ может включать в себя этап, на котором принимают голосовой ввод через микрофон. Цифровой голосовой ввод может быть принят через микрофон. Обработка естественного языка может быть выполнена, используя голосовой ввод, чтобы выявить голосовую команду пользователя. Голосовая команда пользователя может включать в себя запрос на выполнение задачи приложения. Приложению может быть предписано исполнить задачу в качестве фонового процесса без появления пользовательского интерфейса приложения. Пользовательский интерфейс цифрового персонального помощника может предоставлять пользователю ответ на основе принятого состояния, ассоциированного с задачей, так что ответ происходит в контексте пользовательского интерфейса цифрового персонального помощника без демонстрации пользовательского интерфейса приложения. 3 н. и 16 з.п. ф-лы, 10 ил.
Patent RU-2748836-C2 (RU)
Title: Composition containing an acrylic acid derivative and methods for stabilizing acrylic acid derivative
Inventor: KISHIKAWA YOSUKE
IPC: C07C57/76
Filed: 2016-04-08
Granted: 2021-05-31
Abstract: FIELD: polymers.SUBSTANCE: invention relates to a stabilized composition for the production of materials based on acrylic polymers or synthetic intermediates containing (A) a derivative of acrylic acid, represented by Formula (I) (wherein R1and R2are a hydrogen atom; Rcrepresents a group: -OR3(wherein R3is alkyl) or fluorine; and X is fluorine); and (B) amide, wherein the content of the acrylic acid derivative (A) is 30% (wt./wt.) or more. The invention also relates to a stabilization method.EFFECT: method for stabilizing an acrylic acid derivative and a composition containing an acrylic acid derivative in which the acrylic acid derivative is stabilized is proposed.7 cl, 1 tbl, 2 ex
Patent RU-2688023-C2 (RU)
Title: Method of obtaining a welded joint of steel parts resistant to electrochemical corrosion
Inventor: VEREVKIN VALERIJ IVANOVICH
IPC: B23K9/23
Filed: 2017-10-31
Granted: 2019-05-17
Abstract: FIELD: metallurgy. 
     SUBSTANCE: invention can be used in the manufacture of electric arc welding of sheet metal structures, tanks and pipelines for various purposes, in particular ship hulls, oil and gas pipelines. Carry out arc welding in several passes by one-sided or two-sided method with direct current of direct polarity using metal-chemical additive and filler wire as welding materials. Pre-control the silicon content in the steel of the parts to be welded and in the welding material and select them from the condition of obtaining the difference in silicon content ΔSi ≤ 0.30 %. Conduct trial welding of samples with the control of the chemical composition of the weld. When the above-mentioned difference in silicon is 0.30 % between the material of any of the parts and the weld, their selection for the silicon content is adjusted. Gaskets from materials of an intermediate composition over silicon can be used, thus breaking the unacceptable weld joint into several successive welded joints arranged in series. 
     EFFECT: invention allows to reduce the values of thermoelectromotive forces of the neighboring local areas of the weld in contact with electrically conductive fluids, and to increase the resistance of welded joints of metal structures to electrochemical corrosion. 
     1 cl, 1 tbl, 1 ex
Patent RU-2736583-C2 (RU)
Title: Method for producing fish skin and fish skin obtained by a method for producing fish skin
Inventor: Vasenev Aleksandr Valerevich
IPC: C14C3/28
Filed: 2017-12-08
Granted: 2020-11-18
Abstract: FIELD: leather industry. 
     SUBSTANCE: invention can be used in production of fish skin for various purposes and range. Method for production of fish skin includes soaking, removal of scales from skin surface, liming, deliming, softening, degreasing, pickling, tanning, ageing, decolouration, dyeing, greasing and hydrophobization, wherein decolouration is carried out not before degreasing and not later than pickling. In degreasing, Na lauryl sulphate and synthanol are used. Deliming step is carried out in the presence of adipic acid for 4–8 hours. Pickling operation is performed in two stages: at the first stage, the skin is salted in a saturated aqueous solution of table salt, and at the second stage it is treated with acid. Tanning step consists of a preliminary step, on which glutaric aldehyde is used, after which synthetic tannins, Eurosyntan D2 and Eurosyntan M2 are introduced, and the main step, on which synthetic or natural tanning substances are used. Method of producing fish skin in second version provides for liming combined with degreasing. 
     EFFECT: disclosed methods for producing fish skin enable to obtain high-quality non-toxic fish skin without a characteristic "fishy odor" with the ability to produce fish skin in any color. 
     12 cl
Patent RU-2730466-C2 (RU)
Inventor: ALSHEUSKI ALIAKSANDR
IPC: H04N5/232
Filed: 2016-06-16
Granted: 2020-08-24
Abstract: Изобретение относится к оптическим устройствам, например оптическому прицелу огнестрельного оружия, зрительной трубе, биноклю, с широкой областью обзора (field-of-view, FOV) и прицельной сеткой (например, перекрестия, точки и т.д.). Техническим результатом является обеспечение улучшенной осведомленности об обстановке с использованием увеличенной картинки в картинке (picture-in-picture, PIP) внутри оптического изображения FOV. Предложено принятое оптическое изображение обрабатывается для формирования оптического изображения широкой области обзора (FOV), отображаемого на устройстве отображения. Указание принимается для отображения оптического изображения увеличенной PIP на устройстве отображения одновременно с оптическим изображением широкой FOV. Оптическое изображение увеличенной PIP формируется для отображения из центрального участка заданного размера оптического изображения широкой FOV и отображается на устройстве отображения одновременно с оптическим изображением широкой FOV. 3 н. и 15 з.п. ф-лы, 4 ил.
Patent RU-2734756-C2 (RU)
Title: Method for elimination of defects and deformations of lower jaw
Inventor: BAJRIKOV IVAN MIKHAJLOVICH
IPC: A61B17/00
Filed: 2018-06-04
Granted: 2020-10-23
Abstract: FIELD: medicine; maxillofacial surgery. 
     SUBSTANCE: invention discloses a method for mandibular bone plasty. Method consists in growing bone tissue by implanting into a thickness of spongy part of ilium of an implant of porous polytetrafluoroethylene, implant comprises a reconstructive plate for the lower jaw, wound with nonwoven titanium material with through porosity, plate is implanted into spongy part of iliac bone by implant application on pre-decorticated comb of iliac bone with subsequent cultivation for 4 weeks, implant is placed in the lower jaw bone defect area, then prepared implant with saturated bone tissue is intraoperatively re-twisted by non-woven titanium material in accordance with missing volume of soft tissues in lower jaw area, forming a damping pad on which a suspension of autologous multipotent mesenchymal stromal cells is uniformly applied, after which the ends of the plate are fixed to the lower jaw by fixing screws. 
     EFFECT: method allows filling soft tissue complex defect in lower jaw area, reducing traumatism of treatment, reducing resorption of implant and lower jaw. 
     1 cl, 1 ex, 2 dwg
Patent RU-2713388-C2 (RU)
Title: Ship tropospheric radio station
Inventor: Zharovov Aleksandr Klavdievich
IPC: H04B7/22
Filed: 2018-06-09
Granted: 2020-02-05
Abstract: FIELD: radio engineering and communications. 
     SUBSTANCE: invention relates to radio communication and can be used in designing ship tropospheric radio station. To achieve the technical result, a ship tropospheric communication station is proposed, which makes it possible to increase range of communication in the tactical control link of ships in a squadron previously provided by VHF radio stations, from 20 to 200 km and at the same time improve protection of the communication channel from deliberate interference. 
     EFFECT: extended range of communication. 
     1 cl, 2 dwg
Patent RU-2717881-C2 (RU)
Title: Ball hinge for vehicle, primarily for off-road vehicle
Inventor: BRUNNEKE KHANS-GERD
IPC: F16C11/06
Filed: 2016-12-19
Granted: 2020-03-26
Abstract: FIELD: transportation. 
     SUBSTANCE: invention relates to a ball hinge for a vehicle, in particular for an off-road vehicle. Ball joint (20) has housing (21) and ball pin (22) installed in housing (21) with possibility of rotary and turning movement, which shank (23) extends from housing opening (21) outside. Housing bore is protected against undesirable penetration of dirt and/or moisture by means of sealing bellow (25). Sealing bellows (25) for prevention of such damages due to mechanical action by separate sections is enveloped with bellows protective casing (30) so that protective casing (30) of bellows by its inner peripheral surface at least substantially adjoins outer peripheral surface of sealing bellows (25), wherein the inner peripheral surface of the bellows protective jacket (30) is smaller than the outer peripheral surface of sealing bellows (25). 
     EFFECT: technical result is to provide relatively advantageous protective device for sealing bellow protection against damages due to mechanical action. 
     14 cl, 4 dwg
Patent RU-2721176-C2 (RU)
Inventor: GELINAS SIMON
IPC: G06F16/387
Filed: 2017-03-03
Granted: 2020-05-18
Abstract: FIELD: computer equipment. 
     SUBSTANCE: technical result is achieved by determining by means of computing device contextual analytical information based on combination of prediction information from data on current location, real-time data and context data, wherein the contextual analytical information includes a recommendation of actions, purchases and accessories, associated with current location of first user and future location of first user, and real-time data include condition, associated with current location of first user and future location of first user, and context data are associated with interaction between first user and first user device. 
     EFFECT: technical result consists in improvement of accuracy of determination of contextual analytical information of user actions. 
     15 cl, 8 dwg
Patent RU-2724007-C2 (RU)
Title: Снегоуплотнительная машина
Inventor: SPADONI RICCARDO
IPC: B62D31/02
Filed: 2017-04-07
Granted: 2020-06-18
Abstract: Изобретение относится к области транспортного машиностроения. Снегоуплотнительная машина содержит несущий каркас, кабину (5) водителя, установленную на несущем каркасе, два транспортера, установленные на противоположных сторонах несущего каркаса, и пассажирскую кабину, отделенную от кабины водителя и установленную на несущем каркасе. Пассажирская кабина содержит опорную конструкцию. Опорная конструкция образует защитную камеру, выполненную с возможностью выдерживать внешние нагрузки, и содержит посадочные места. Пассажирская кабина содержит панели из прозрачного материала, предпочтительно стекла, которые частично соединены с посадочными местами опорной конструкции и поддерживаются опорной конструкцией. Достигается увеличение количества мест для перевозки пассажиров. 10 з.п. ф-лы, 3 ил.
Patent RU-2756521-C2 (RU)
Title: Corrosion-prone borehole product
Inventor: WILKS TIMOTHY
IPC: C22C23/06
Filed: 2018-01-09
Granted: 2021-10-01
Abstract: FIELD: metallurgy. 
     SUBSTANCE: invention relates to magnesium alloy; it can be used as a borehole tool for hydraulic fracturing. Magnesium alloy, suitable for use as a corrosion-prone borehole product, contains, wt.%: 2-7 Gd, 0-1 Y, 0-5.0 Nd, 0-0.5 Zr, 0.1-2 Ni, magnesium and unavoidable impurities - the rest, while the alloy has relative elongation measured according to the ASTM B557M-10 standard of at least 22%.  
     EFFECT: invention is aimed at increasing the ductility of the alloy while maintaining the level of corrosion characteristics. 
     13 cl, 1 dwg, 1 tbl
Patent RU-2744914-C2 (RU)
Title: Monoclonal binding agents, their drug conjugates and their applications
Inventor: CORONELLA JULIA
IPC: C07K16/28
Filed: 2017-09-28
Granted: 2021-03-17
Abstract: FIELD: immunology.  
     SUBSTANCE: present group of inventions relates to immunology. Disclosed is a binding agent that is an antibody or its antigen-binding fragment and specifically binds to the extracellular domain of the mesenchymal-epithelial transition factor (cMET). Also described is a method of treating an object having a neoplastic disorder or cancer, and a pharmaceutical composition. 
     EFFECT: group of inventions can find application in the therapy of various diseases associated with cMET.  
     15 cl, 12 tbl, 6 ex, 16 dwg
Patent RU-2771310-C2 (RU)
Inventor: KAUMANS Rudi Gerardus Elizabet
IPC: C07K16/30
Filed: 2018-05-22
Granted: 2022-04-29
Abstract: FIELD: medicine. 
     SUBSTANCE: invention relates to a method for obtaining antibody-drug conjugates and to antibody-drug conjugates, where an antibody contains a constructed cysteine residue in a position 41 of a heavy chain in accordance with Kabat system, where therapeutic groups are conjugated with one or more constructed cysteine residues, as well as with one or more restored cysteine residues from an interchain connection, by means of a cleavable or non-cleavable linker.  
     EFFECT: method allows for regulation of DAR of obtained antibody-drug conjugates, obtaining product with insignificant amount of the unreacted antibody; the antibody-drug conjugate has reduced hydrophobicity favorably affecting pharmacokinetic properties of the conjugate. 
     11 cl, 5 dwg, 1 tbl, 1 ex
Patent RU-2751273-C2 (RU)
Title: Two-stroke internal combustion engine
Inventor: SIDELNIKOV STANISLAV GRIGOREVICH
IPC: F02B19/16
Filed: 2020-11-24
Granted: 2021-07-12
Abstract: FIELD: mechanical engineering.SUBSTANCE: invention can be used in internal combustion engines. The internal combustion engine contains a cylinder (1) with a piston (2), a combustion chamber (3) and a pre-chamber (4). The pre-chamber (4) contains an ignition cavity (5) installed in the combustion chamber (3) and made in the form of a hemisphere. The longitudinal axis of the ignition cavity (5) coincides with the longitudinal axis of the cylinder (1). The ignition cavity (5) faces the outlet towards the piston (2). The approximate value of the distance from the side walls of the cavity (5) of the ignition of the pre-chamber (4) to the piston (2) at its upper dead center at the end of the compression stroke is determined from the ratio h=R/2π mm. Where h is the distance from the side walls of the ignition cavity of the pre-chamber to the piston at its upper dead center at the end of the compression stroke, R is the radius of the inner spherical surface of the ignition cavity, π =3.14…EFFECT: improved eco-friendly characteristics.1 cl, 1 dwg
Patent UA-54602-C2 (UA)
Title: Method of combined no moldboard layer wise cultivation and a ripper for carrying out thereof
Inventor: SYSOLIN PETRO VASYLIOVYCH
Filed: 2000-12-22
Abstract: A method of combined no moldboard layer wise soil cultivation according to which the soil loosening to an agriculturally grounded depth is carried out layer wise and simultaneously in several horizons per passage. In doing so each horizon is loosened for an insignificant depth (8... 12 сm) and in such a way that a starting period of loosening of the lower layers of the general layer takes place at a point of time when the adjacent upper soil layer is in the suspended state yet and does not touch a layer of the lower horizon next to it, as a result of that the process of soil loosening in all the horizons takes place under conditions similar to the conditions of loosening the surface layer. If required, after the layer wise cultivation the upper soil layer is additionally loosened up to the aggregate state, which fits for carrying out the sowing. The method of combined no moldboard layer wise soil cultivation, which is provided by a ripper, allows increasing the quality and evenness of loosening of the soil along the total depth of a layer cultivated, decreasing the total power-consuming of the production process and on the account of this raising the productivity of the aggregate, аnd also practically excludes the probability of revealing ecologically dangerous phenomena.
Patent UA-62317-C2 (UA)
Title: Device for obtaining single-crystal ingots
Inventor: AZHAZHA VOLODYMYR MYKHAILOVYCH
IPC: B22D27/15
Filed: 2003-03-04
Abstract: The invention relates to the nonferrous metallurgy, namely - to the design of device for obtaining the single-crystal ingots. A device for obtaining single-crystal ingots contains a vacuum chamber, in which are placed a heater, a crystallizer installed under the heater, a ceramic mold with a seed located inside the heater with possibility of movement towards to the crystallizer with its sinking in liquid metal cooler from light alloy. The seed is made in the form of a flat element, the ratio of transverse size of which to the thickness makes not less than 10:1, in this case in the initial state the seed is located higher than the lower cut for the value not large than 0.15òN, where ? - height of heater. The invention ensures the increase of suitable products û single-crystal ingots with assigned crystallographic orientation.
Patent UA-76794-C2 (UA)
Title: Photocatalitical active mesoporous titanium dioxide, process and intermediate product for its preparation
Inventor: MANORYK PETRO ANDRIOVYCH
IPC: C01B3/06
Filed: 2004-06-03
Abstract: Mesoporous titanium dioxide contains crystalline phase of anatase in the amount not less than 30 per cent by weight, it has porous structure with average diameter of pores from 2 to 16 nm, specific surface area not less than 70 m2/g. The process for preparation of the mesoporous titanium dioxide includes introduction to water-organic solvent which contains not more than 7 per cent by weight of water of a precursor – titanium tetra-alkoxide and template of organic nature in the form of one of ligands selected from the group of macro-cyclic compounds, comprising oxa- and oxa-substituted compounds which contain not less than four atoms of oxygen, and/or from the complexes of said macro-cyclic compounds with metal ions selected from the group of alkaline or alkaline-earth, or f-metals, including lithium, potassium, sodium, rubidium, cesium, magnesium, calcium, strontium, barium, lanthanum and cerium, mixing the mixture of reagents at a temperature not higher than 35 °C up to formation of the ashes, mixture conditioning at the same temperature in open container under conditions of free access of water vapor to it from outside up to final formation of spatial structure, separation of obtained product of reaction and its treatment prior to removal of the template. The obtained product as a catalyst of photochemical reaction of separation of hydrogen from aqueous-alcoholic mixtures provides quantum yield of reaction not less than 0.5 in the presence of palladium or platinum catalyst of dark stage of reaction.
Patent UA-76800-C2 (UA)
Title: Filtering system for protection against biological agents and connector
Inventor: CERBINI STEFANO
IPC: A62B18/00
Filed: 2002-12-11
Abstract: The invention refers to a filtering system composed by a face mask and a filter against biological agents, joined together by a new connector. The connector joins the filter to the mask in an easy, fast and effective way. The filtering system provides a very high barrier against biological agents, a high seal and is very easy to use.
Patent UA-80446-C2 (UA)
Title: Method for psychophysiologic assessment of the readiness of person for psychophysiologic assay
Inventor: ZAKHARASH MYKHAILO PETROVYCH
IPC: A61B5/053
Filed: 2005-04-26
Abstract: The invention relates to the medicine, namely to psychophysiology and may be used for the particular psychophysiologic studies. The method of the psychophysiologic study is realized by recording the skin galvanic reactions upon presenting the cards with the conditionally significant images to the persons under the assay.