baber/WOPTO huggingface dataset:
Patent CA-2868259-A1 (CA)
Title: Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate
Inventor: KAYE JOEL FLAXMAN
IPC: A61K31/4704
Filed: 2013-03-26
Abstract: This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the subject laquinimod as an add-on therapy to or in combination with DMF. This invention also provides a package comprising laquinimod and DMF for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides laquinimod for use as an add-on therapy or in combination with DMF in treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides a pharmaceutical composition comprising laquinimod and DMF for use in treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention further provides use of laquinimod and DMF in the preparation of a combination for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome.
Patent CA-2870822-A1 (CA)
Title: Trans-2-decenoic acid derivative and drug containing same
Inventor: IINUMA MUNEKAZU
IPC: A61P25/24
Filed: 2013-04-26
Abstract: The present invention pertains to: a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof; and a drug containing the compound as the active ingredient. Specifically, the trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof is represented by general formula (I) (in the formula, X indicates a substituent group such as 1-pyrrolidilyl, 3-thiazolidyl, or piperidino), and is highly useful as a drug such as a prevention or treatment agent for peripheral nerve disorders resulting from anti-cancer drug administration, a prevention or treatment agent for neurodegenerative disorders or psychiatric disorders including dementia, Alzheimer's disease, Parkinson's disease, diabetic neuropathy, depression, glaucoma, and autism spectrum disorders, a treatment or repair agent for spinal injuries, an analgesic for various pain disorders, and the like.
Patent CA-2872777-A1 (CA)
Inventor: FELDHAUS ANDREW LAWRENCE
IPC: A61K39/395
Filed: 2013-05-08
Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for PCSK9. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-PCSK9 antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-PCSK9 antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-PCSK9 antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with PCSK9.
Patent CA-2873909-A1 (CA)
Title: Interactive network and/or devices and/or methods thereof
Inventor: FASTING NIKOLAI
IPC: H04N21/45
Filed: 2014-12-09
Abstract: Networks and/or devices for enabling and/or providing live or non-live interactivity with televised programming and/or its viewers and/or fans and/or hosts and/or actors and/or contestants. In certain (non-limiting) embodiments, mobile or handheld devices (e.g., mobile phones or laptops) communicably connected or connectable to networks having platforms thereon for permitting or providing live or real-time interactivity with televised programming and/or its viewers/fans/hosts/actors/ contestants.                          In other embodiments, methods for performing or providing the interactivity described herein. In still other embodiments, software, residing on a data storage device, which directs a processor to perform actions in accordance with and/or to obtain one or more of the objectives of the technologies and methods described herein.
Patent CA-2874867-A1 (CA)
Inventor: RUBIN HARVEY
IPC: H04W16/00
Filed: 2013-06-13
Abstract: The present disclosure is related to a large-scale broadband wireless network capable of providing a very high wireless data capacity. The broadband wireless network may combine proven leading edge commercial wireless design and architecture methodologies with advanced RF technologies to substantially improve spectrum efficiency, spectrum usage, and data performance, including beam forming, optimization servers, beam forming operations, locating and tracking user equipment, data transmission and reception control, reduction of inter-cell interference, delivery of real-time services, conserving back-haul, integration of a sensor platform, capability for implementing a dual-use network, data rate priority usage, usage-data reporting, mobile base-station replacement, and active hot standby redundancy.
Patent CA-2876303-A1 (CA)
Title: Use of epigenome-modifying compounds for the treatment of genetic muscular diseases linked to a protein-conformational disorder
Inventor: RICHARD ISABELLE
IPC: A61K31/19
Filed: 2013-07-16
Abstract: Use of at least one epigenome-modifying compound for the preparation of a medicament and for the treatment of genetic muscular diseases linked to a conformational disorder of at least one protein, said disorder causing the cellular degradation of the protein.
Patent CA-2876908-A1 (CA)
Inventor: BRYJA VITEZSLAV
IPC: A61K31/506
Filed: 2013-08-05
Abstract: The invention provides new medicaments for the treatment of the B-cell chronic lymphocytic leukemia, which are inhibitors of casein kinase 1.
Patent CA-2877882-A1 (CA)
Title: Inteines clivees, conjugues et utilisations de celles-ci
Inventor: MUIR TOM W
IPC: C07K16/18
Filed: 2013-06-24
Abstract: L'invention concerne des intéines clivées, des protéines fusionnées d'intéines clivées, et des procédés d'utilisation d'intéines clivées pour purifier et modifier de manière efficace des protéines d'intérêt.
Patent CA-2880993-A1 (CA)
Title: Hcv ns3 protease inhibitors
Inventor: BARA THOMAS
IPC: C07D491/107
Filed: 2013-08-06
Abstract: The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.
Patent CA-2881500-A1 (CA)
Inventor: SHEFFIELD MATTHEW S
IPC: E04F15/00
Filed: 2015-02-11
Abstract: A method of making a composite panel configured for use with a flooring assembly of a trailer includes providing a wood substrate, making an uncured fiber-reinforced coating, and applying the uncured fiber-reinforced coating onto a surface of the wood substrate. The method further includes curing the uncured fiber-reinforced coating after applying the uncured fiber-reinforced coating onto the surface of the wood substrate.
Patent CA-2882466-A1 (CA)
Title: System and method for positioning an automated assembly tool relative to a structure
Inventor: REID ERIC M
IPC: B25J9/00
Filed: 2015-02-18
Abstract: A method and apparatus for positioning an end effector relative to a structure. The apparatus may comprise the end effector and a sensor system. The end effector may be configured to perform an operation on the structure. The sensor system may have a plurality of sensors extending outward from the end effector.
Patent CA-2882660-A1 (CA)
Inventor: ONFFROY JOSHUA P
IPC: H04L12/24
Filed: 2013-08-23
Abstract: A technique for managing an electronic system suitable for providing users with information technology resources, such as compute, storage, and network resources, builds an object model instance of data center components to represent the data center components as a unified entity, which administrators can access as a single-point source for information about the components. In some examples, the object model instance also serves as a single-point for management control of the electronic system. The object model instance is populated with information obtained from a discovery process, where components are queried to report their actual configuration and state, as well as physical and logical relationships among them.
Patent CA-2884045-A1 (CA)
IPC: A47F7/00
Filed: 2015-03-09
Abstract: A device for securing an elongate article comprising four finned holder elements, each finned holder element being fabricated of an elastomeric material, the four finned holder elements being oriented in two pairs, a top pair and a bottom pair, each pair having a left and right finned holder element which are mirror images of each other.  The element are upwardly disposed relative to the horizontal, and have a side portion contiguous with an upper portion, a base portion, and a back portion and a free edge having a receiving portion and a linear securing portion having a recess. A  housing member having left and right cavities holds the left and right finned holder elements in opposing juxtaposition and has a rear portion with a vertical support that separates a left through-hole and a right through-hole.
Patent CA-2885403-A1 (CA)
Title: Conduit for the removable positioning of temperature sensors in a water heater and method
Inventor: LESAGE CLAUDE
IPC: F24H1/20
Filed: 2015-03-18
Abstract: A passage is provided in a water heater and mounted against the outer surface of the water tank side wall to removably mount thermistors secured to a support at distinct locations along the tank side wall to provide temperature value signal representative of the water temperature in the tank adjacent the thermistors. The passage may be formed by a metal tube held next to the side wall of the tank or a U-shaped channel held against the outer surface of the tank wall with the through thereof facing the tank side wall outer surface. The thermistors are mounted spaced-apart on a support inserted in the passage. The method is also described.
Patent CA-2886286-A1 (CA)
Inventor: LEIVA ILLANES RICARDO
IPC: C22C38/18
Filed: 2013-07-25
Abstract: Provided is a method for producing steel having high wear resistance, a mainly bainitic microstructure, and a balance of tensile strength and hardness for large pieces in mining operations the chemical composition of which steel, in weight percentage, comprises: 0.30-0.40% C, 0.50-1.30% Si, 0.60-1.40%  Mn, 2.30-3.20% Cr, 0.0-1.00% Ni, 0.25-0.70% Mo, 0.0-0.50% Cu, 0.0-0.10% Al, 0.0-0.10% Ti, 0.0-0.10% Zr, <0.050% P, <0.050% S, <0.030% N, optionally <0.050% Nb, optionally 0.0005-0.005% B, optionally 0.015-0.080% rare earth metals, residual contents of W, V, Sn, Sb, Pb and Zn of <0.020%, and the balance in iron.  The method includes melting and heat treatment. The resulting steel exhibits a suitable balance of the chemical composition, tensile strength and hardenability for complete hardening in large cast pieces, typically up to 17 inches thick, with a preferable Brinell hardness of 385-495 BHN and excellent resistance to wear by abrasion impact.
Patent CA-2886331-A1 (CA)
Inventor: ITAY NEHEMYA
IPC: H01Q7/00
Filed: 2013-09-17
Abstract: A proximity integrated circuit card (PICC) is disclosed comprising a main loop antenna to transmit data from said PICC and a secondary loop antenna to receive RF transmission to said PICC. The main antenna and the secondary antenna arranged to yield low mutual magnetic coupling so that the RF transmission to the PICC yields bigger signal in the secondary antenna than the signal that yields in the secondary antenna from a transmission from the main antenna. According to some embodiments the secondary antenna is arranged to only partially overlap said main antenna.
Patent CA-2887187-A1 (CA)
Inventor: SULLIVAN TIMOTHY R
IPC: B65D77/38
Filed: 2008-05-15
Abstract: Formes dosifiées contenant des compositions pharmaceutiques conçues pour être utilisées dans des dispositifs permettant une administration par pulvérisation ou brumisation des compositions. Linvention comprend des compartiments thermoformés de dosage et un compartiment thermoformé de distribution. La compression des compartiments permet de distribuer les compositions de la manière souhaitée sous forme de pulvérisation. Certaines formes dosifiées comprennent plusieurs chambres de dosage, chacune contenant un composant ou une partie dune composition pharmaceutique, dont les contenus sont mélangés ou combinés juste avant ou pendant ladministration.
Patent CA-2888245-A1 (CA)
Title: Method and system for monitoring subsurface injection processes using a borehole electromagnetic source
Inventor: ALUMBAUGH DAVID LEE
IPC: E21B47/00
Filed: 2014-03-03
Abstract: A method and a system for providing electromagnetic measurement in a rock formation are provided. The system includes a borehole casing (50B) having a plurality of casing segments (52B). At least two casing segments (53B) of the plurality of casing segments are electrically isolated from each other. The system further includes an electromagnetic source (71A-C) positioned on a surface of the earth. The electromagnetic source is connected to the at least two casing segments. The electromagnetic source is configured to energize the at least two casing segments so as to generate an electromagnetic field in the rock formation around the borehole casing.
Patent CA-2888594-A1 (CA)
Inventor: MASSAULT LAETITIA
IPC: H05B3/86
Filed: 2013-10-04
Abstract: Polymeric vehicle glazing (1) at least comprising an outer face (I) and an inner face (IV), a transparent polymeric component (2) at the outer face (I) and the inner face (IV), an opaque polymeric component (3) flush mounted at the inner face (IV) in at least one section of the transparent polymeric component (2).
Patent CA-2891495-A1 (CA)
Inventor: SIL SAMIK
IPC: G01V1/30
Filed: 2013-11-15
Abstract: A method of event location to avoid first break picking when signals are small or the ambient noise level is high is described. In this method traveltime associated with the maximum amplitude phases (for any mode of wave) are identified and picked from one or more sensors in an array. Difference between the arrival times are then calculated. A grid search (or optimization) techniques are then employed to search for the event location to match the observed time differences.
Patent CA-2892353-A1 (CA)
Inventor: LANGE JEAN-PAUL
IPC: C07C51/00
Filed: 2014-01-08
Abstract: The invention relates to a process for producing acrylic acid, comprising: converting a C3-oxygenate into a C3-hydroxyacid, wherein said C3-oxygenate is selected from the group consisting of 1-propanol, 2-propanol, propanal, acetone, monopropylene glycol, monohydroxyacetone, 2- hydroxypropanal, dihydroxyacetone and 2,3- dihydroxypropanal; and converting the C3-hydroxyacid into acrylic acid.
Patent CA-2893239-A1 (CA)
Inventor: LYNCH STEPHEN M
IPC: C07D409/12
Filed: 2013-11-29
Abstract: The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.
Patent CA-2893897-A1 (CA)
Inventor: PATEL JAYANTILAL DEVABHAI
IPC: A23D9/00
Filed: 2015-06-05
Abstract: Une variété de canola désignée 46M34 et la semence, les plants et parties de plants produits à partir dun testeur commun sont décrits. Les procédés pour produire une variété de canola comprennent le croisement de la variété de canola 46M34 avec un autre plant de canola. Des procédés sont décrits pour produire un plant de canola qui renferme dans son matériel génétique au moins un des traits introgressés dans la 46M34 par conversion rétrocroisée et/ou transformation rétrocroisée, et les semences, plants et parties de plant du canola produits de ce fait. La variété de canola 46M34, les semences, les plants produits à partir des semences, les parties de plant et les variantes, mutations et légères modifications de la variété de canola 46M34 sont divulgués.
Patent CA-2896157-A1 (CA)
Inventor: IHSSEN JULIAN
IPC: C12N15/73
Filed: 2013-12-24
Abstract: The present invention provides novel methods of producing diphtheria toxin. In particular, the present invention provides novel methods of producing nontoxic forms of diphtheria toxin, e.g., CRM197. The present invention also provides novel compositions comprising diphtheria toxin or nontoxic forms of diphtheria toxin, e.g., CRM197.
Patent CA-2896598-A1 (CA)
Inventor: WRIGHT ERIC C
IPC: B60T17/06
Filed: 2015-07-08
Abstract: A branch pipe tee for a rail car having a length that is below standard. The branch pipe tee has a standard mount for connecting to the brake pipe and branch pipe as well as integral volume that compensates for the reduced brake pipe length of the rail car. The integral volume is dimensioned to make the effective brake pipe length of rail car fall within standard ranges so that the braking system of the rail car can perform normally and avoid the need for additional equipment to compensate for the length of the rail car.
Patent CA-2897536-A1 (CA)
Title: Resonator device for electron spin resonance
Inventor: MOHEBBI HAMIDREZA
IPC: G01R33/36
Filed: 2014-01-31
Abstract: In some aspects, a resonator device for spin resonance applications is described. In some examples, the resonator device includes a substrate, terminals, and resonators. The terminals include a first terminal having first terminal segments disposed on a substrate surface, and a second terminal having second terminal segments disposed on the substrate surface opposite the first terminal segments. The resonators include conductors disposed on the substrate surface between the first and second terminals. Each conductor is disposed between one of the first terminal segments and a respective, opposite one of the second terminal segments.
Patent CA-2900152-A1 (CA)
Inventor: JUAREZ ALEJANDRO
IPC: E21B17/042
Filed: 2014-01-28
Abstract: A metal-to-metal sealing system connecting first and second tubular members includes a first seal configuration on the first tubular member and a second seal configuration on the second tubular member. The first seal configuration includes a first annular groove and a first annular tooth, and the second seal configuration includes a second annular groove and a second annular tooth. The second annular tooth is positioned within the first annular groove with the second annular tooth face engaging the first annular shoulder face to define a first shoulder. The first annular tooth is positioned within the second annular groove with the first annular tooth face engaging the second annular shoulder face to define a second shoulder. Locations of primary sealing contact of surfaces of the members are spaced axially away from the first and second shoulders.
Patent CA-2900272-A1 (CA)
Inventor: COOTE MICHELLE LOUISE
IPC: C07B61/00
Filed: 2014-02-06
Abstract: Described herein are distonic radical anion species of formula (I): RAD-L-NEG; wherein RAD is a group comprising a radical; NEG is a group comprising an anion, which is capable of bonding to a proton or other cation; L is a linker that links NEG to RAD; and the radical of RAD is not p-conjugated to the anion of NEG.
Patent CA-2903132-A1 (CA)
Inventor: NEIBART STEVEN
IPC: A61P35/00
Filed: 2014-03-04
Abstract: The present invention relates to the compound having the following formula: (I), which may be in base form or in the form of a hydrate or a solvate, in combination with prednisone or prednisolone, for its use for the treatment of castration resistant or hormone-refractory metastatic prostate cancer in patients not at risk of developing gastrointestinal disorders chosen from the group consisting of: gastrointestinal bleeding and perforation, gastritis, enterocolitis, neutropenic enterocolitis, colitis, intestinal obstruction, and ileus.
Patent CA-2904927-A1 (CA)
Inventor: ROBINSON EDWARD G
IPC: F16N1/00
Filed: 2015-09-23
Abstract: A greasable hood pin assembly that allows for lubrication between the hood and the bushing of a backhoe. The hood pin assembly comprises a lubricant nipple; a bolt comprising a longitudinal inner compartment for reception of the lubricant, the compartment extends from a top portion of the bolt into the bolt interior; and one or more bolt apertures,; and a bushing comprising a lubricant groove around the circumference of the bushing; and one or more bushing apertures along the lubricant groove, with each bushing aperture extending from the cylindrical surface of the bushing into a hollow portion of the bushing. The lubricant nipple is inserted into a top top portion of the bolt; and the bolt is inserted longitudinally into the bushing.
Patent CA-2906791-A1 (CA)
Inventor: FRIESEN FRANK
IPC: B60P1/43
Filed: 2014-03-14
Abstract: A trailer having a trailer ramp system that includes a trailer ramp coupled with the trailer and an actuator pivotally coupled to the trailer on a first end of the actuator and pivotally coupled to the trailer ramp on a second end of the actuator. The actuator is located below the trailer and is aligned with a central axis of the trailer ramp and a central axis of the trailer. The actuator is movable linearly to rotate the trailer ramp between an open position and a closed position.
Patent CA-2912559-A1 (CA)
Inventor: LOUWERS MARIEKE
IPC: C12N15/82
Filed: 2014-05-19
Abstract: Plants having one or more enhanced yield-related traits and a method for making the same are provided. It relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, a method for enhancing one or more yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a POI (Protein Of Interest) polypeptide is provided. Plants having modulated expression of a nucleic acid encoding a POI polypeptide are also provided, which plants have one or more enhanced yield-related traits compared with control plants. Hitherto unknown POI-encoding nucleic acids and constructs comprising the same useful in performing the method are also provided.
Patent CA-2915694-A1 (CA)
Title: Wireless recharging system and method for flexible implantable subcutaneous medical device
Inventor: AMIR JACK
IPC: H02J50/10
Filed: 2015-12-22
Abstract: Flexible subcutaneous implantable medical device (IMD), including an elongated and flexible body, a plurality of electronic components, at least one rechargeable battery, at least one antenna, at least one lead and at least one transition unit, the antenna for receiving and transmitting electromagnetic radiation and the lead for providing an electric shock, wherein the elongated and flexible body is structured from a plurality of units, wherein a first one of the plurality of units encapsulates the rechargeable battery, wherein each one of the other plurality of units respectively encapsulates a respective one of the plurality of electronic components, wherein the antenna is positioned in the transition unit, wherein the transition unit is covered with a biocompatible polymer, wherein the antenna receives electromagnetic radiation for recharging the rechargeable battery and wherein the antenna includes a copper coil having a generally cylindrical shape.
Patent CA-2915697-A1 (CA)
Inventor: ALBANO CHRISTOPHER
IPC: H04W36/06
Filed: 2015-12-18
Abstract: Provided are methods and systems for, in some aspects, mitigating interference over a communication channel. In an aspect, a device can be configured to detect interference and to dynamically reconfigure to avoid interference. Such a device can be configured to receive content over various communication channels and can intelligently select a communication channel to avoid interference.