baber/WOPTO huggingface dataset:
Patent BE-1005406-A0 (BE)
Title: Procede de preparation d'intermediaires utiles dans la synthese de benzothiazepines.
Inventor: GHIROTTO LUCA
IPC: C12P41/00
Filed: 1991-05-16
Abstract: Procédé de préparation de composés de formule (voir figure 1), dans laquelle R est un groupement alkyle en C1-C8 linéaire ou ramifié, un groupement cycloalkyle en C5-C8 ou un groupement 2,2-diméthyl-1,3-dioxolanne-4-méthyle, par transestérification enzymtique de mélanges énantiomères. Les composés obtenus sont des intermédiaires utilisables dans la synthèse du diltiazem.
Patent IL-65595-A0 (IL)
Title: Novel dioxaheterocyclic compounds,processes for their manufacture and pharmaceutical compositions containing them
IPC: A61P7/10
Filed: 1982-04-23
Abstract: The invention relates to novel dioxaheterocyclic compounds of the formula I    <IMAGE>  (I)  in which R1 represents an unsubstituted or substituted aromatic or heteroaromatic radical or an unsubstituted or lower alkylated, mono- or bi-cyclic cycloaliphatic hydrocarbon radical or an  alpha -branched aliphatic hydrocarbon radical, each of R2 and R3, independently of the other, represents hydrogen or lower alkyl, and each of R4 and R5, independently of the other, represents hydrogen, lower alkyl or halogen, and A represents the radical -O-R6, wherein R6 represents hydrogen or an unsubstituted or substituted aliphatic or araliphatic hydrocarbon radical or A represents the radical   <IMAGE>  in which each of R7 and R8, independently of the other, represents hydrogen or lower alkyl, or R7 and R8 are bonded to one another and, together with the adjacent nitrogen atom, represent unsubstituted or lower alkyl-substituted tetra- to hexa-methyleneimino or 4-morpholinyl, and the divalent radical in formula I is either in the 4,5- or the 5,6-position and correspondingly R4 and R5 are in positions 6 and 7, or 4 and 7, respectively, of the benzodioxole skeleton, to salts of compounds of the formula I in which A represents OR6 wherein R6 represents hydrogen, with bases, as well as acid addition salts of compounds of the formula I in which the radical R1 is of basic character, and to pharmaceutical compositions containing them. These novel substances have a diuretic activity and, in addition, a uricosuric activity, and can be administered, according to the invention, preferably in the form of corresponding pharmaceutical compositions, to mammals for the treatment of oedema and hypertension.
Patent IL-65734-A0 (IL)
Title: Process for the preparation of 3,3-dimethylglutaric acid
IPC: C07C51/285
Filed: 1982-05-11
Abstract: 1. Process for the production of 3,3-dimethyl glutaric acid from isophorone, characterized by treating isophorone with hydrogen peroxide in the presence of strong acids at temperatures of from 10 to 80 degrees C.
Patent IL-79316-A0 (IL)
Title: Improved dental appliance
IPC: A61C13/235
Filed: 1986-07-02
Abstract: A denture-retaining unit comprises a ball and socket structure, the socket being adapted for incorporation into a denture. The ball is a sphere having a truncated portion providing a flat base adapted for magnetic engagement with a flat face of a magnetizable keeper, which keeper is adapted to be secured to a support member extending from the jaw. A characterizing feature of the unit is that it permits lateral movement between the denture in which the socket is embedded and the keeper, while the flat faces of the keeper and the sphere remain fully magnetically engaged.
Patent IL-93445-A0 (IL)
Title: Connecting means for a toy building element
IPC: A63H33/12
Filed: 1990-02-19
Abstract: A connecting system for a toy building set comprises a first coupling part (11) and a second coupling part (12, 13), which are provided on their respective ones of a pair of building elements, adapted to be interconnected, and are formed with respective complementary coupling elements (11, 12, 13). The coupling parts in the connecting elements of the invention are adapted to interconnect the elements by elastic movement of at least one coupling part. This interconnection is flexible and may be fixed with a clamping device (16), which blocks the elastic movement.
Patent IL-94062-A0 (IL)
Title: Pyrimidine derivatives
IPC: C07D409/12
Filed: 1990-04-11
Abstract: This invention concerns novel aminopyrimidinium salts of the formula I:  <IMAGE>  in which R1 is alkyl, alkenyl, cycloalkyl, phenyl, phenylalkyl or cycloalkyl-alkyl; one of R2 and R6 is a basic group selected from amino, alkylamino, dialkylamino of up to eight carbon atoms, pyrrolidino, piperidino and morpholino; and the other of R2 and R6 is hydrogen, alkyl, alkenyl, alkoxyalkyl, phenyl, phenylalkyl, cycloalkyl or cycloalkyl-alkyl; or both of R2 and R6 are basic groups as mentioned above; and R5 is hydrogen, (1-4C)alkyl or (3-6C)alkenyl; or R2 is a basic group as mentioned above, and R5 and R6 together form alkylene or, together with the appendant carbon atoms of the pyrimidine ring, complete a benzene ring; R4 is hydrogen, alkyl, cycloalkyl-alkyl, alkenyl, alkynyl or phenylalkyl; or R4 is an optionally substitutued alkylene or alkenylene linked to the nitrogen atom of the group Q.A.N-, either of which linking groups may thereby completing a ring including two adjacent carbon atoms of Q, the carbon atoms of A and the adjacent nitrogen atom of the group -A.N-; A is a direct bond to the the group -N(R4)- or is alkylene or oxyalkylene; Q is a pyridyl, furyl, thienyl or phenyl moiety; and Y is a physiologically acceptable anion; but excluding a number of compounds specified hereinafter. The invention also includes certain closely related anhydro-base derivatives which, like the formula I compounds, possess beneficial effects on the cardiovascular system (and in particular beneficial effects modulated via the sino-atrial node). Also included are pharmaceutical compositions containing the formula I compound (or a related anhydro-base) as active ingredient, and processes for the manufacture of the various novel compounds.
Patent IL-97404-A0 (IL)
Title: Preparation of 1,5-benzothiazepine derivatives
IPC: C07D281/10
Filed: 1991-03-04
Abstract: There is disclosed a process for preparing 1,5-benzothiazepine derivatives of the formula: <CHEM>  wherein R<1> is a lower alkyl group, or a salt thereof which comprises subjecting a propionate derivatives of the formula: <CHEM> wherein R<2> is an ester residue and R<1> is the same as defined above, to intramolecular cyclization in the presence of a sulfonic acid compound of the formula: <MATH> wherein R<3> is a lower alkyl group or a substituted or unsubstituted phenyl group, in a non-halogenated organic solvent and, if desired, converting the product to a salt thereof.
Patent FI-20011474-A0 (FI)
Inventor: AHO ERKKI
IPC: D21F3/02
Filed: 2001-07-05
Abstract: An assembly is disclosed for connecting and securing to each other rolls (1, 2) forming a nip in an extended nip press, whereby at least one of the rolls (1) of the extended-nip press includes loading means (3), advantageously at least one loading shoe for loading the endless-loop blanket (4) of one roll (1) against the other one (2) of the extended-nip press rolls so as to establish a nip (N), wherein the lower roll (1) and the upper roll (2) are dismountably connected to each other and the assembly connecting the rolls (1, 2) of the extended-nip press to each other includes rotatable connecting members (7, 8) by means of which the extended-nip press rolls (1, 2) are detachably connected to each other by their bearing blocks (5, 6). The invention is characterized in that the connecting member (7, 8) is pivotally coupled to the first bearing block (5) by means of a pivot pin (9) equipped with an oblique or any similar key surface (24) adapted mating with a first clamping surface (17) of the connecting member (7, 8).
Patent FI-20050215-A0 (FI)
Inventor: TAMMELA SIMO
IPC: G02B/
Filed: 2005-02-23
Abstract: The invention relates to a process of preparing an optical fiber joint, wherein an optical fiber or its undrawn precursor is brought into contact with a longitudinal element and attached to it via a ridge-groove fitting prior to drawing of the final optical fiber joint. The longitudinal element can be another optical fiber or its precursor or a removable and/or workable bridging element.
Patent IL-101708-A0 (IL)
Title: Anti-fattening drugs
IPC: A61P3/04
Filed: 1992-04-28
Abstract: Obesity is treated by the administration to a subject of a compound having the general formula (I): R4-(CH2)n-CO-N(R1)-CH(R2)-CO(-R3), wherein R1 represents H or CH3; R2 represents a side chain of a naturally occurring amino acid; R3 represents OH, OCH2CH3 and NH2; n is 6-18; and R4 represents CH3 or a group having the general formula (II): R3-CO-CH(R2)-N(R1)-CO-, wherein R1, R2 and R3 have the above meanings. The compounds of formula (I) wherein R4 is a group of formula (II), are novel compounds.
Patent IL-103107-A0 (IL)
Title: Mixtures of 1,1,1-trifluoroethane,perfluoropropane and propane,and their use as refrigerant fluids,as aerosol propellants or as blowing agents for plastic foams
IPC: C07C9/08
Filed: 1992-09-08
Abstract: To replace chlorofluorocarbons as refrigerant fluids, the invention proposes to employ mixtures containing, on a mass basis, approximately 25 to 65 % of 1,1,1-trifluoroethane, 1 to 70% of perfluoropropane, and 5 to 34 % of propane. The mixtures according to the invention can also be employed as aerosol propellants or as blowing agents for plastic foams.
Patent IL-110132-A0 (IL)
Title: Plant-microbicidal compositions and their use
IPC: A01N43/40
Filed: 1994-06-27
Abstract: Plant microbicide composition comprises at least 2 active components in a ratio providing a synergistic fungicidal activity. The composition comprises a first component (I) selected from fludioxonil (i.e. 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile) (Ia) and a 4-(dihalophenyl)-1H-pyrrole-3-carbonitrile of formula (Ib); and a component (II) comprising 2-phenylamino-4-cyclopropyl-6-methyl-pyrimidine. R1 = F or Cl; R2 = Cl or CF3.
Patent IL-114788-A0 (IL)
Title: Method and device for extinguishing fires
IPC: A62C3/02
Filed: 1995-07-31
Abstract: PCT No. PCT/EP95/02964 Sec. 371 Date Sep. 27, 1996 Sec. 102(e) Date Sep. 27, 1996 PCT Filed Jul. 26, 1995 PCT Pub. No. WO96/04960 PCT Pub. Date Feb. 22, 1996What is disclosed is a device for extinguishing fires, and utilization of the device for stationary protection of specific objects, and for dust abatement during blasting operations, and a method for extinguishing forest or terrain fires with the extinguishing device. The extinguishing device comprises a container for receiving an extinguishing agent, and an explosive in or on this container, by means of detonation of which the extinguishing agent is atomized to form a mist and brought into the fire. In order to increase the flexibility and effectiveness in practical use, the container consists of a flexible hose which may be closed at both ends. The method of extinguishing forest or terrain fires with this device provides for the hose to be laid out in front of the fire front, filled with the extinguishing agent, and exploded by detonation of the explosive.
Patent IL-129409-A0 (IL)
Title: 1-Phenylpyrazole compounds and pharmaceutical compositions containing the same
IPC: C07D231/14
Filed: 1997-10-22
Abstract: 1-Phenylpyrazole compounds of the formula (1): <CHEM> which is exemplified by 5-amino-1-(3-cyano-4-isobutoxyphenyl)pyrazole-4-carboxylic acid, an optical isomer thereof and a pharmaceutically acceptable salt thereof. These compounds have a xanthine oxidase inhibitory activity and are useful as therapeutic agents for diseases such as hyperuricacidemia and gout.
Patent IL-159792-A0 (IL)
Title: Variolin derivatives and pharmaceutical compositions containing the same
IPC: C07D471/22
Filed: 2002-07-11
Abstract: Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X 2 , R 1 , R 2 , R 3 , R 6 , R 7  and R 12  are each independently selected from the group consisting ofH, OH, OR', SH, SR', SOR', SO 2 R', NO 2 , NH 2 , NHR' (N(R') 2 , NHCOR', NHSO 2 R', CN, halogen, =O C(=O)H, C(=O)R', CO 2 H, CO 2 R', carboxyalkyl, C 1-12  alkyl, C 2 -C 12  alkenyl, C 2 -C 12  alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; wherein each of the R' groups is independently selected from the group consisting of H, OH, SH, NO 2 , NH 2 , CN, halogen, =O, C(=O)H, C(=O)CH 3 , CO 2 H, CO 2 CH 3 , C 1 -C 12  alkyl, C 2 -C 12  alkenyl, C 2 -C 12  alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups R 1  and R 2 , R 2  and R 3 , R 3  and R 12 , R 12  and R 6 , or R 6  and R 7  may be joined into a carbocyclic or heterocyclic ring system.
Patent IL-161842-A0 (IL)
Title: 2-Amino-4-heteroarylethyl-thiazoline derivatives and their use as inhibitors of inducible no-synthase
IPC: C07D239/26
Filed: 2002-11-07
Abstract: The present invention relates to the use of 2-amino-4-heteroarylethyl-thiazoline derivatives of formula (I)in which Het represents a thienyl, pyrimidyl, pyridyl or thiazolyl radical or pharmaceutically acceptable salts thereof as inhibitors of inducible NO-synthase.
Patent IL-162408-A0 (IL)
Title: Use of pramipexole to treat amyotrophic lateral scelrosis
IPC: A61K/
Filed: 2002-12-02
Abstract: The present invention is directed to compositions comprising pramipexole and the use of such compositions treat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). As shown in  Fig. 6B  the mean + 1 -SEM serum 2,3-DHBA levels for the 12 ALS participants decreased significantly after pramipexole treatment.
Patent IL-189256-A0 (IL)
Title: Device for receiving or holding several substrates and galvanizing device
Filed: 2008-02-04
Abstract: In order to treat solar cells in an electroplating device, they can be inserted into a grid-like or tray-like picking-up device. They are thus mechanically held and electrical contact is made with them via contacts. Instead of individual solar cells, the picking-up devices are moved with a large number of inserted solar cells through the electroplating device for treatment. Electrical contact with the solar cells is in this case made via the contacts and the frame limbs on a projecting angle section together with edge strips of the pick-up. Contact rollers rest on the edge strips and are connected to an electrical power source.
Patent RO-126920-A0 (RO)
Title: Needle for draining the macular hole
Inventor: BALTĂ FLORIAN
IPC: A61M5/32
Filed: 2011-07-15
Abstract: The invention relates to a needle for draining the macular hole used in surgical ophthalmological interventions and to a process for carrying out the same. According to the invention, the needle consists of a connector () connected to a cylindrical tube () with a size in the range 0.9...0.33 mm, which is ended with a taper region, having a suction end provided with a diaphragm with micrometric dimensions. The claimed process consists in cold plastic deforming the end of a tube having dimensions close to the ones of a syringe needle, so that this receives a taper shape both to the outer side and to the inner side, followed by removing by abrasive chipping the material from the taper end until the resulting plane surface intersects the inner taper surface there resulting a diaphragm.
Patent RO-129640-A0 (RO)
Title: Aerodynamic assembly and method for simulating floating condition
Inventor: MATEI DANIEL ION
IPC: B64D23/00
Filed: 2014-03-26
Abstract: The invention relates to an aerodynamic assembly meant to produce an air jet of sufficiently large area and sufficient intensity for it to be able to sustain a person in the air, as well as to a method for simulating the floating condition. According to the invention, the assembly comprises an outer cover (4) consisting of a fixed platform of convex profile, having an upper flange (7) made of several pairs of circular crown sectors, on which a hydraulic machine (3) driven by an electric motor (11) is assembled, coaxially with the outer cover (4) there being a central torus (2) represented by a round moulding of convex profile, with the base opening smaller than the upper termination of the torus (2), where the outer cover (4) is so shaped that it enables the fluid jet to attach itself to a convex wall (8), leading to a depression occurring on the outer surface of an adjacent wall (9), the fluid being accelerated between the central torus (2) and the convex wall (8), entering an orifice (10) for accelerating the jet in the central torus (2) and entraining the fluid in the hydraulic machine (3) at a higher pressure than the previous pass. The method, as claimed by the invention, consists in placing an object in respect of which simulation is carried on, starting a hydraulic machine at the nominal rotation speed to reach balance, and, when the object is floating, the rotation speed of an electric motor is reduced, resulting in the decrease of the energy consumption, at the end the steps being carried out backwards up to the object return to the base.
Patent RO-134710-A0 (RO)
Title: Electronic system for diagnosing noises and vibrations of motor vehicles
Inventor: BUJOREANU CARMEN
IPC: G06N3/02
Filed: 2020-07-16
Abstract: The invention relates to an electronic system for diagnosing the noises and vibrations of motor vehicles, with the possibility of accurately identifying the noise source. According to the invention, the system comprises a set of digital or analogue sensors (1), which are mounted on the vehicle subjected to diagnosis and which cooperate with an ECU computer (2) which analyzes the values transmitted by the sensors, based on parameters stored in a memory of the ECU computer (2).
Patent RO-135118-A0 (RO)
Title: Metal-mesoporous oxide nanocomposite materials for storing thermal energy at high temperatures
Inventor: LINCU DANIEL-FLORIAN
IPC: C09K5/06
Filed: 2021-03-09
Abstract: The invention relates to metal-mesoporous oxide nanocomposite materials and to a process for preparing them, the nanocomposite materials being meant to be used for storing thermal energy as latent heat and sensible heat at high temperatures. According to invention, the material consists of a nanocomposite material containing silica or mesoporous silicate with the role of support and metallic or semi-metallic nanoparticles with the role of storing thermal energy at high temperatures above 200°C, the mesoporous oxide containing pores of average size between 2...50 nm and total pore volumes between 0.4...4 cm3/g, and the metals/semi-metals have melting points between 200...1000°C and contain only chemical elements less electropositive than silicon, the nanocomposite materials having a mesoporous oxide content of between 10...50% by mass and having one or more reversible solid-liquid or solid-solid phase transitions. The production process, as claimed by the invention, has the following steps: a. loading the mesoporous oxide support with metallic precursors by impregnation or adsorption of the precursors from the solution and, optionally, separation of the composite material precursor -mesoporous oxide, b. chemical reduction of metallic precursors using reducing agents such as sodium borohydride, hydrazine, ethylene glycol, citric acid, oxalic acid, formic acid, or other reducing agents, c. separation of the nanocomposite by centrifugation, filtration, decantation and purification by usual methods of washing with solvents, acids and/or bases to remove unreacted precursors.
Patent AP-2002002624-A0 (AP)
Title: Use of a combination of compounds in a dry powder inhaler.
Inventor: HUMPHREY MICHAEL JOHN
IPC: A61P11/06
Filed: 2002-09-12
Abstract: The present invention relates to an inhaled formulation comprising a combination of a compound selected from a particular class of 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-a]pyridines of the formula (i)and a tiotropium salt or solvate threof, which is capable of delivering the compound of the formula (i)as fine, solid particles to the lung. The invention also relates to the use of such a formulation in the treatment of certain disease such as respiratory diseases. By the use of such formulations, it is possible to eliminate the unwanted cough response associated with the use of the compounds of the formula (i)in solution metered dose inhalers, which response can prevent the administration of a therapeutically effective dose and, in the long term, undermine patient compliance.
Patent AP-2004003022-A0 (AP)
Title: Intraorally disintergrating valdecoxib compositions prepared by spray drying process
Inventor: SHAH UDAY J
IPC: A61P11/02
Filed: 2002-10-10
Abstract: Orally disintergrating valdecoxib fast-melt tablets and processes for preparing such dosage forms are provided. The compositions are useful in treatment or prophylaxis of cycloosygenase-2 mediated conditions and disorders.
Patent AP-2004003122-A0 (AP)
Title: Cloning of cytochrome P450 genes from nicotiana
Inventor: XU DONGMEI
IPC: C12N15/09
Filed: 2003-03-12
Abstract: The present invention relates to P450 enzymes and nucleic acid sequences encoding P450 enzymes in nicotiana, and methods of using those enzymes and nucleic acid sequences to alter plant phenotypes.
Patent MA-23167-A1 (MA)
Inventor: AUGUSTIN GONZALEZ OCEJO
IPC: C06B47/14
Filed: 1994-04-19
Abstract: The composition is of watergel type containing oxidiser salts, sensitisers, thickeners, crosslinking agents, fuels and water. The sensitiser includes more than 50% by weight of one or more water soluble compounds of oxygen balance more positive than -150% selected from salts of nitric, chloric and perchloric acid with acylic nitrogen bases, having no more than two hydrogen atoms bonded to the or each basic nitrogen atom and up to three carbon atoms per basic nitrogen atom, and the salts of nitric, chloric, and perchloric acid with a phenyl amine, and the water content is less than 10% by weight, of the composition. The process comprises (a) to mix (i) a thickened aqueous phase containing an aqueous solution of water soluble sensitisers, thickeners and optionally a portion of the oxidiser salt, with (ii) a dry phase containing oxidiser salts along with the remaining additives and (b) to reduce the density of the mixture. The compositions are capable of initiation by a number 6 strength detonator in small diameter at low temperatures and they have a rheology allowing them to be cartridged in paper cartridges.
Patent MA-27314-A1 (MA)
Title: Procede d'individualisation d'un terminal relie a au moins un serveur a travers un reseau
Inventor: GRUNENWALD RODOLPHE
IPC: H04M17/02
Filed: 2004-12-30
Abstract: Le procédé d'individualisation d'un terminal (10) relié à au moins un serveur (5) à travers un réseau (2) comprend les étapes suivantes: a) au niveau du terminal (10), établir une session de connexion (20) avec le serveur (5), et b) au niveau du serveur (5), traiter la session de connexion selon un mode opératoire choisi. Le mode opératoire comprend les étapes suivantes: c) au niveau du serveur (5), en cas de demande de service du terminal incluse dans la session de connexion, générer un certificat (ESN) unique associé audit terminal (10), et communiquer ledit certificat audit terminal; d) au niveau du terminal (10), recevoir et stocker ledit certificat (ESN); et e) au niveau du serveur (5), valider la demande de service avec le terminal ainsi individualisé de manière unique.
Patent MA-37549-A1 (MA)
Title: Extrudeuse pour plastique mono vis
Inventor: CHHIM ANAS
IPC: B29B7/14
Filed: 2014-11-17
Abstract: Une extrudeuse destinée au recyclage de plastique usé comprenant une boite cylindrique (5), une vis d’alimentation (4) en rotation dans le cylindre (5) chauffée (8), une buse de sortie (9) sur l’extrémité de la boite cylindrique pour une sortie de plastique en ficelle.
Patent MA-37749-A1 (MA)
Inventor: PALMARINI MASSIMO
IPC: C12N7/00
Filed: 2013-06-13
Abstract: يحتوي الاختراع الحالي لقاحات btv و ashv أو التركيبات وطرق لإنتاج ناقلات هجين معدلة وراثيا من btv و ashv وطرق التقليد ضد btvو ashv.
Patent MA-38339-A1 (MA)
Title: Indicateur d'usure dans un système composite constitué de blocs céramiques réfractaires
Inventor: KLIKOVICH MICHAEL
IPC: C04B41/00
Filed: 2014-03-13
Abstract: L'invention concerne un indicateur d'usure dans un système composite constitué de blocs céramiques réfractaires.