baber/WOPTO huggingface dataset:
Patent CO-6331440-A2 (CO)
Title: Hidroximetil pirrolidinas como agosnistas del receptor adrenergico beta 3
Inventor: BERGER RICHARD ALAN
IPC: A61K31/4178
Filed: 2010-10-04
Abstract: 1.- Un compuesto de Fórmula la, o una de sus sales farmacéuticamente aceptables, o un estereoisómero del mismo, o una sal farmacéuticamente aceptable del estereoisómero del mismo:en la quen es 0, 1, 2, 3, 4 ó 5;Y se selecciona entre el grupo constituido por:(1) alcanodiílo C1-C5, alquenodiílo C2-C5, y alquinodiílo C2-C5, en la que cada alcanodiílo, alquenodiílo y alquinodiílo está opcionalmente sustituido con uno a tres grupos seleccionados independientemente entre halógeno, ORa, y -S(O)p-alquilo C1 -C3, en la que p es 0, 1 ó 2;(2) -(CRaRa)j-Q-(CRaRa)k, en la que j y k son números enteros seleccionados independientemente entre 0, 1 y 2.(3) un enlace, y(4) fenileno opcionalmente sustituido con uno a tres grupos seleccionados independientemente entre R1;Z se selecciona entre el grupo constituido por:(1) fenilo,(2) un anillo heterocíclico de 5 ó 6 miembros con 1 a 4 heteroátomos seleccionados entre oxígeno, azufre y nitrógeno,(3) un anillo de benceno condensado con un anillo carbocíclico C5-C10,(4) un anillo heterocíclico de 5 ó 6 miembros con 1 a 4 heteroátomos seleccionados entre oxígeno, azufre y nitrógeno condensado con un anillo heterocíclico de 5 ó 6 miembros con 1 a 4 heteroátomos seleccionados entre oxígeno, azufre y nitrógeno, y(5) un anillo heterocíclico de 5 ó 6 miembros con entre 1 a 4 heteroátomos seleccionados entre oxígeno, azufre y nitrógeno condensado con un anillo carbocíclico C5-C10;R1 se selecciona entre el grupo constituido por:(1) alquilo C1 -C5 opcionalmente sustituido con 1 a 5 átomos de halógeno,(2) cicloalquilo C3-C6,(3) halógeno,(4) nitro, ...
Patent CO-6311008-A2 (CO)
Title: Composicion farmaceutica que comprende un agente que activa las celulas t regulatorias cd4+cd25+
Inventor: AIGNER SILKE
IPC: C07K16/28
Filed: 2010-10-13
Abstract: La presente invención proporciona una composición farmacéutica para tratar una enfermedad autoinmune que comprende un portador farmacéutico aceptable y un agente capaz de activar células T regulatorias CD4+CD25+ en donde la composición se va a administrar a un sujeto, cuando más cada 3 días.
Patent CO-6361920-A2 (CO)
Title: Derivados de (fenil)-amida del acido 7-(piperazin-1-ilmetil)-1h-indol-2-carboxilico y compuestos relacionados en calidad de inhibidores de map-quinasa p38 para el tratamiento de enfermedades de las vias respiratorias
Inventor: WAGNER HOLGER
IPC: A61K31/404
Filed: 2011-03-16
Abstract: La presente invención pone a disposición compuestos de acuerdo con la fórmula general (I)que se proponen para el tratamiento de enfermedades de las vías aéreas, en especial de asma y EPOC.
Patent CO-6640209-A2 (CO)
Title: Heteroaril-ciclohexil-tetraazabenzo[e]azulenos como antagonistas del receptor v1a de la vasopresina
Inventor: DOLENTE COSIMO
IPC: C07D487/04
Filed: 2012-09-24
Abstract: La presente invención se refiere a heteroaril-ciclo-hexiltetraazabenzo[e]azulenos de la fórmula Ien la que R, Ry Rtienen los significados aquí descritos.Los compuestos de la invención actúan como moduladores del receptor de la V1a y en particular como antagonistas del receptor de la V1a; la invención se refiere además a su obtención, a las composiciones farmacéuticas que los contienen y al uso de los mismos como medicamentos. Los compuestos activos de la presente invención son útiles como agentes terapéuticos que actúan a nivel periférico y central en los estados patológicos tales como la dismenorrea, disfunción sexual masculina o femenina, hipertensión, fallo cardíaco crónico, secreción inapropiada de vasopresina, cirrosis hepática, síndrome nefrótico, ansiedad, trastornos depresivos, trastorno obsesivo-compulsivo, trastornos del espectro autista, esquizofrenia y conducta agresiva.
Patent CO-6680718-A2 (CO)
Title: Lámina de acero para contenedores y método para fabricar la misma
Inventor: SUZUKI TAKESHI
IPC: C23C28/00
Filed: 2013-03-21
Abstract: Una lámina de acero para contenedores que tiene excelentes calidades de adhesión de película, y tiene: [un recubrimiento de conversión química formado al sumergir y/o someter a tratamiento electrolítico una lámina de acero en una solución que contiene iones de Zr, iones de E, con cantidad de adhesión de 0.1 a 100 mg/m2 para el Zr metálico y no más de 0.1 mg/m2 para F; y una capa de tratamiento de hidroxil ácido formada sobre el recubrimiento de conversión química, la capa que tiene una cantidad de adhesión de C de 0.05 a 50 mg/m2.
Patent EP-1039443-A2 (EP)
Inventor: WEBER OTTO DIPL-ING
IPC: G10K11/172
Filed: 2000-03-06
Abstract: The air noise absorbing form part, particularly for motor vehicle bodywork, has an outside and an inside directed toward at least one noise source. The outside and the inside are connected to form hollow spaces over wall components. The inside has at least one opening for one of the hollow spaces. The at least one hollow space (18) with the opening (20) has an intermediate wall (24) forming a double chamber. In the intermediate wall a further opening (28) is provided.  The chambers (26') of the at least one hollow space have volumes of different sizes. The openings (20,28) have different cross-sections, or can have the same cross-section. The wall sections (30) between the hollow spaces of the inside are formed as plate absorbers.
Patent EP-1055589-A2 (EP)
Inventor: SCHOENEGGER-FOESLEITNER ERICH
IPC: B62D35/00
Filed: 2000-03-21
Abstract: The holder incorporates a support device for the spoiler. The device consists of two pivoted (7) parallel support bars (8) w associated clamp units (9). Each clamp unit consists of a sliding block on the cab roof (2), with stop face for a support bar, a hand grip/wheel (14), which has a threaded stud passing through a bore (13) in the bar, and screwed into the block. The hand gri in/directly locks the bar via a clamp plate (15). Sliding block and support bars have elements (17) for positive locking.
Patent EP-1051032-A2 (EP)
Inventor: BOON CATHY L
IPC: H01L27/14
Filed: 2000-05-03
Abstract: Improved imaging system includes a CMOS imaging chip with a light
blocking layer configured so as to block incident light from a portion of the
readout circuitry sensitive to light. The light blocking layer may be positioned on
top of a glass package housing the imaging chip or may be incorporated in the
manufacture of the chip itself Distortions in image data due to lighting conditions
in outdoor applications are avoided by the presence of the light blocking layer
resulting in improved image quality under such conditions.
Patent EP-1068862-A2 (EP)
Title: Desodorierende Wirkstoffkombination und deren Verwendung
Inventor: DIEHL ILSE
IPC: A61K8/34
Filed: 2000-05-08
Abstract: Wirkstoffkombination als wirksames Prinzip zur Verwendung in kosmetischen Desodorantien auf der Basis eines synergistischen Gemisches aus (A) mindestens einem mehrwertigen Alkohol mit 5 bis 15 Kohlenstoffatomen, insbesondere einem 1,2-Diol, und (B) mindestens einem Citronensäuretrialkylester. Beansprucht wird ferner ein Verfahren zur Bekämpfung des durch mikrobielle Zersetzung apokrinen Schweißes hervorgerufenen menschlichen Körpergeruches, dadurch gekennzeichnet, daß eine wirksame Menge des Gemisches aus (A) und (B), gegebenenfalls in einem geeigneten kosmetischen Träger, auf die Haut aufgetragen wird.
Patent EP-1049356-A2 (EP)
Inventor: GRONET CHRISTIAN M
IPC: H01L21/00
Filed: 1991-01-18
Abstract: An apparatus for the rapid thermal processing of a substrate, comprises: an assembly of
radiant energy sources disposed outside of a process chamber, said radiant energy sources
having a central longitudinal axis that extends in a substantially perpendicular direction
relative to a window of the process chamber and subsets of said radiant energy sources
disposed at different radii of the assembly and each radiant energy source terminating in a
common plane adjacent to the window; and reflectors to guide a substantial quantity of
radiant energy from said radiant energy sources to portions of a substrate in said chamber,
said reflectors extending along at least a major portion of a length of said radiant energy
sources and the walls of said reflectors extending in a substantially perpendicular direction
relative to said window, and said radiant energy sources and said reflectors positioned so that
a portion of the substrate radiated by one of said radiant energy sources overlaps a portion of
the substrate radiated by another one of said radiant energy sources to provide a substantially
uniform radiation intensity pattern across the substrate.
Patent EP-1087301-A2 (EP)
Inventor: GRUENEWALD UWE
IPC: G06F17/30
Filed: 2000-09-11
Abstract: The data base system includes a memory- and/or load module (11) which manages a number of information objects (18) in a data base (16). The information objects can store classes for receiving references to other information objects. A query- and/or input module communicating with the memory- and/or load module, records and processes a hierarchical query system (13), in which queries (14) are hierarchically tied with each other, and are associated with a class of the information object.
Patent EP-1063307-A2 (EP)
Inventor: VIRNIG MICHAEL
IPC: C25C1/12
Filed: 1996-05-30
Abstract: An improved process is described for the recovery of copper from an
aqueous feed solution using solvent extraction and electrowinning in which the
electrowinning is conducted in a first step wherein the electrolyte is flowing
perpendicular to the cathode surface without auxiliary mixing of the electrolyte
between electrodes, and a second step wherein the electrolyte is flowing parallel
to the cathode surface. In a second embodiment, solvent extraction of copper
and solvent extraction of acid are conducted in alternate steps to allow more
complete recovery of copper.
Patent EP-1108644-A2 (EP)
Inventor: KIKUNO JUNJI
IPC: B62J9/00
Filed: 2000-11-17
Abstract: A battery 63 which is smaller than a
luggage box 61 is arranged in front of the luggage box 61,
and the battery 63 and the luggage box 61 are covered by
a seat lower cover 64 in said order whereby the seat
lower cover 64 can be made into a convergent shape as
viewed in plan. 
     For example, the width of the seat 62 located
above the seat lower cover 64 can be narrowed according
to the need. That is, the seat lower cover 64 can be made
into a convergent shape as viewed in plan whereby an
enlargement of freedom of design can be intended.
Patent EP-1103260-A2 (EP)
Inventor: FISCHER WILFREID
IPC: A61K31/4168
Filed: 2000-11-29
Abstract: Transdermal patch for delivery of clonidine (I) comprises a (I)-containing adhesive layer based on a 2-ethylhexyl acrylate/vinyl acetate copolymer or a styrene block copolymer.
Patent EP-1111227-A2 (EP)
Inventor: THIERY CHRISTOPH
IPC: F02M26/50
Filed: 2000-12-14
Abstract: The exhaust gas feedback valve has a linearly displaced valve element, e.g. a valve plate (18), which is rotated about its axis, at least at the beginning of its movement, via the valve element operating mechanism, e.g. a spindle-and-nut operating mechanism (22,24).
Patent EP-1134155-A2 (EP)
Inventor: LIM PUAT THIAM
IPC: B62M9/127
Filed: 2000-12-14
Abstract: A cable saver mechanism (12) is provided in a cable (18) of a cable operated component,
such as a rear derailleur (14), to protect the cable operated component or a part
of the bicycle when the bicycle falls over and the cable operated component, e.g., the
rear derailleur (14), hits the ground. The cable saver mechanism (12) has a first
housing portion (40), a second housing portion (42) and a biasing member (44) disposed
between the first (40) and second (42) housing portions to urge them apart from
each other. The first housing portion (40) has a first tubular section (50) with a first
end wall (52) and first open end (54) spaced from the first end wall (52). The first
end wall (52) includes a first cable bore (60) with an internal section (62) becoming
wider towards the first open end (54). The second housing portion (42) has a second
tubular section (80) with a second end wall (82) and second open end (84) spaced
from the second end wall (82). The second end wall (82) includes a second cable
bore (90). The first (54) and second (84) open ends of the first (40) and second (42)
housing portions are movably coupled together. The biasing member (44) is disposed
between the first (52) and second (82) end walls to urge the first (40) and second (42)
housing portions apart from each other.
Patent EP-1115068-A2 (EP)
Inventor: DOMON WATARU
IPC: G06F13/40
Filed: 2000-12-21
Abstract: A connection controller for a serial bus network includes physical
layer processing circuitry for performing the protocol of the physical layer of
the network to establish communications with first, second and third nodes.
The first node is specified as an initiator node and the second node is a target
node of the first node. The physical layer processing circuitry is energized by
power supplied from the first node. To reliably establish connections
between desired nodes in a first-to-win racing environment, a delay time is
introduced in response to the physical layer processing circuitry being
energized. During the delay time, a logical connection is established between
the first and second nodes and the third node is set in a disabled state.
Patent EP-1053735-A2 (EP)
Inventor: NANAHARA KENJI
IPC: A47C21/08
Filed: 2000-04-12
Abstract: A lifting side rail mechanism for a bed or the like comprises at least one side rail frame
(112) having at least two side rail members (113,114) pivotally mounted at each end
of respective support arms (108) pivotally connectable to a bed base (102) or other
fixed support (103) such that the side rail frame (112) can be moved by rotation of the
support arms (108) between a service position with the side rail members (113,114)
of the side rail frame (112) spaced from one another and above the plane of the bed
base (102) and a lowered, stowed position, in which the upper side rail member is
lowered to the same level as or below the plane of the bed base (102). The
connections of the side rail members (113,114) to the support arms (108) are such that
the separation of the side rail members (113,114) increases to a maximum as the
support arms (108) are turned to move the side rail mechanism between the service and
stowed positions and is less than this maximum in each of the service and stowed
positions.
Patent EP-1058145-A2 (EP)
Inventor: GILL DOUGLAS M
IPC: G02F1/225
Filed: 2000-05-23
Abstract: The specification describes a Mach-Zehnder electro-optic modulator
device in which the ridge containing the waveguides in the interactive
electro-optic regions have re-entrant sidewalls. This shifts the peak in the
RF field profile to below the surface of the ridge and closer to the peak of
the optical field, thereby producing a device with reduced drive voltage.
Patent EP-1063843-A2 (EP)
Inventor: SATO HIROKAZU
IPC: H04N5/232
Filed: 2000-05-26
Abstract: A display unit of an image pick-up apparatus
is provided with a touch panel (2) (contact-position
detecting device) on the image display screen of
the display unit and is used by inverting (0 and 180
degrees) or rotating (opening/closing state) the image
display screen. An orientation detecting device (5) is provided
for detecting the orientation of the display unit. A table (4)
is provided for storing relationships between the coordinate
positions of the touch panel and predetermined processing.
When a predetermined operating part of the touch panel is
touched, it is transformed into a coordinate position of the
touch panel, and the predetermined processing corresponding
to this coordinate position is performed.
Patent EP-1078732-A2 (EP)
Inventor: GOTOU YUUJI
IPC: B29D11/00
Filed: 2000-08-25
Abstract: A mold assembly for forming an ophthalmic lens article such as
an ophthalmic lens and an intermediate product for the
ophthalmic lens, the mold assembly consisting of a first mold (10)
and a second mold (12), the first and second molds being
assembled together to define a mold cavity (24) therebetween
having a profile corresponding to that of the ophthalmic lens
article, the mold cavity being filled with a polymeric material (32)
which is polymerized to form the ophthalmic lens article,
wherein: at least one of the first and second molds (10, 12) is a
resin mold which is formed of a resin material, a portion (19) of
at least a molding surface (16) of the resin mold being irradiated
directly with a UV radiation so as to provide a UV-treated
surface (28), the ophthalmic lens article formed in the mold
cavity being held on the resin mold such that the ophthalmic lens
article adheres to the UV-treated surface, when the first and
second molds are separated away from each other.
Patent EP-1118939-A2 (EP)
Inventor: ALDRIDGE DAVID
IPC: G06F11/36
Filed: 2000-12-27
Abstract: A method of debugging software arranged to run on a microcontroller for the purpose of
controlling a macrocell associated with the microcontroller 1. The method comprises
the steps of populating fields of a debugger application 3 using macrocell specific data
read electronically from a database 4, said fields including at least a parameter name
field and a parameter location field. One or more of the populated fields is displayed on
a graphical user interface of the debugger application 3. User initiated debugging
related instructions are relayed to the microcontroller 1 from the debugger application 3,
whilst response data is received from the microcontroller 1 at the debugger application
3. The received response data is displayed to the user on the graphical user interface of
the debugger application 3.
Patent EP-1049182-A2 (EP)
Inventor: RAVET NATHALIE
IPC: H01M4/583
Filed: 2000-05-02
Abstract: An electrode material, comprising complex oxide particles with a homogeneous conductive carbon-based material coating, is ne An electrode material, comprising a complex oxide of formula AaMmZzOoNnFf, in which A = an alkali metal, M = one or more transition metals and optionally a non-transition metal, Z = one or more non-metal and a, m, z, o, n and f are ≥ 0 and are chosen to provide electrical neutrality, has a homogeneous conductive carbon-based material coating to provide a regular electric field distribution at the material grain surfaces. Independent claims are also included for the following: (i) a process for carbon-based material deposition on the above electrode material by pyrolysis of a polymer (mixture), dispersed in the complex oxide, in vacuum or an inert gas atmosphere; (ii) a process for carbon-based materia deposition on the above electrode material by dismutation of carbon-based material monoxide, optionally mixed with an inert gas, below 900 degrees C optionally in the presence of a catalyst; (iii) a process for preparing the above electrode material by pyrolysis of an organic derivative of an alkali metal (A) to form a carbon-based material deposit on the complex oxide surface a to supply a portion of the alkali metal content of the complex oxide; and (iv) an electrochemical cell having one or more electr of the above electrode material.
Patent EP-1106987-A2 (EP)
Inventor: ZIEGLER DIPL ING WERNER
IPC: G01N21/64
Filed: 2000-11-30
Abstract: The measurement chamber has a base (1) and cover (2) part that are at least partly transparent for stimulation and measurement radiation and form a measurement channel (3) when assembled and luminescence optical sensor elements (4) in a sensor region. The base and cover parts contain longitudinal grooves (11) forming the measurement channel. Sensor elements in both grooves have an optical covering layer (12) over the entire sensor region.
Patent EP-1189575-A2 (EP)
Inventor: KLEIMAN ROBERT
IPC: A61K8/00
Filed: 2000-06-09
Abstract: L'invention concerne une composition émolliente comprenant un ester éthylique à chaîne longue combiné à des systèmes stabilisant l'oxydation qui comprennent au moins un tocophérol et au moins un additif supplémentaire sélectionné dans le groupe constitué d'acide kojique, d'acide malique et d'acide ascorbique. L'ester éthylique à chaîne longue peut comprendre un ester éthylique d'une huile naturelle et avoir une insaturation interrompue par méthylène inférieure à 20 %. La composition émolliente peut comporter un additif supplémentaire présent dans des quantités comprises entre 0,01 et 2 % en poids ou plus, le tocophérol étant présent dans des quantités comprises entre 0,01 et 5 % en poids. La composition émolliente comporte de préférence un ester éthylique à chaîne longue sélectionné dans la classe constituée d'ester éthylique d'huile de macadamia, d'ester éthylique d'huile de tournesol hybride, d'ester éthylique d'huile de babassu et d'écume des près ayant une insaturation interrompue par méthylène inférieure à 5 %.
Patent EP-1279047-A2 (EP)
Inventor: TRAN MY
IPC: B64F1/00
Filed: 2000-04-07
Abstract: La présente invention concerne un système anticollisions (MCAS) qui fait appel à un concept existant de système de surveillance du trafic et d'évitement des collisions (TCAS) sous forme de module (20) et lui intègre de façon transparente un module tactique personnalisé (22) capable d'assurer un affichage et un contrôle de pilotage d'évitement tactiques uniques.  Le module tactique gère toutes les phases d'une mission tactique, y compris le vol en formation (62) (par exemple, le rassemblement en formation, le vol en formation armé, la poursuite en formation et le décrochage de formation), et la séquence de ravitaillement en vol (64), (par exemple, le rendez-vous, la jonction, le ravitaillement en carburant et le dégagement).  Le module tactique divise l'espace aérien qui entoure l'aéronef en zones de service consultatif (84), zones de restriction (82) et zones d'avertissement (80) et il émet pour chacune d'elles des alarmes visuelles, sonores et vocales qui facilitent les commandes immédiates de pilotage d'évitement.  La présente invention permet par conséquent aux aéronefs militaires d'éviter les situations de collision en vol et de quasi-abordage dans les trois modes de fonctionnement : le mode de gestion par le service du contrôle de la circulation aérienne, le mode tactique et un mode mixte.
Patent EP-1418856-A2 (EP)
Inventor: FREEMAN JERRE M
IPC: A61F9/01
Filed: 2000-08-10
Abstract: Système de poursuite et de positionnement de l'oeil conçu pour être utilisé avec un ensemble laser à réfraction et comprenant une interface de caméra, un ordinateur et un dispositif servant à déplacer le patient par rapport au faisceau laser. L'ordinateur comprend un numériseur vidéo qui extrait des images de l'oeil depuis la caméra et est programmé afin d'exécuter un algorithme de poursuite de l'oeil. Cet algorithme calcule le centre exact de la pupille oculaire et compare ce centre avec l'emplacement souhaité du faisceau laser, déterminé par le chirurgien, au moyen d'un algorithme de traitement d'image. Si l'emplacement relatif du centre de l'oeil et du faisceau laser sont en dehors d'une valeur prédéterminée, le fauteuil du patient et, par conséquent, le patient, sont repositionnés par rapport au faisceau laser, à l'inverse du repositionnement du faisceau laser par rapport au patient. Ce repositionnement corrige le déplacement de l'oeil.
Patent EP-1214411-A2 (EP)
Inventor: ATKINSON PAUL ROBERT
IPC: A61K33/24
Filed: 2000-08-31
Abstract: The present invention provides compounds, which comprise a protease-resistant FLINT analog complexed with a divalent metal cation, pharmaceutical formulations thereof, and methods of using such compounds for treating or preventing diseases related to the FasL/Fas interaction.
Patent EP-1267913-A2 (EP)
Inventor: SIM KIM LEE
IPC: A61K31/675
Filed: 2000-11-10
Abstract: La présente invention concerne des compositions et des méthodes destinées au traitement de maladies associées à la multiplication anormale des cellules et plus particulièrement du cancer. Les compositions et les méthodes de la présente invention utilisent des doses décroissantes d'agents chimiothérapeutiques et antiangiogéniques. En particulier, la présente invention concerne des méthodes permettant d'administrer de faibles doses d'endostatine. L'invention concerne également des méthodes de schématisation antiangiogénique d'un ou plusieurs agents thérapeutiques.