baber/WOPTO huggingface dataset:
Patent AU-2021356099-A1 (AU)
Title: Screening method for the identification of novel therapeutic compounds
Inventor: HENTZE MATTHIAS W
IPC: C12N9/88
Filed: 2021-10-06
Abstract: The present invention pertains to a method for identifying and/or characterizing a compound suitable for the prevention and/or treatment of a disease. The invention is based on the finding that the glycolytic enzyme Enolase 1 (ENO1) binds RNA, and its enzymatic activity is thereby regulated. The invention is further based on the finding that riboregulation of ENO1 affects cell differentiation, which plays a pivotal role in cancer. Accordingly, the invention provides a screening method for novel therapeutic compounds based on the binding of RNA to ENO1. Compounds screened according to the present invention can affect the binding of RNA to ENO1, which harbors the therapeutic potential for the treatment of diseases, in particular proliferative diseases, such as cancer. Methods of treatment using these compounds, as well as pharmaceutical compositions thereof, are also provided.
Patent AU-2021371931-A1 (AU)
Title: Ground-engaging apparatus and method for configuring the same
Inventor: HELDAL JIM
IPC: E02F9/28
Filed: 2021-10-28
Abstract: The disclosure is directed to a ground-engaging apparatus (50) that is mountable at a distal end of an articulated arm of a ground- excavating machine, wherein the ground-engaging apparatus includes a plurality of teeth (28) arranged in a row for engaging onto ground to be excavated; and wherein the teeth are retained onto a carrier of the ground-engaging apparatus via corresponding locking pins, wherein the locking pins are configured to be ejected automatically after the teeth have undergone a threshold amount of wear, thereby enabling the teeth when worn to be removed and replaced
Patent AU-2021373188-A1 (AU)
Title: Chimeric protein comprising the receptor binding domain of the coronavirus spike protein and compositions comprising them
Inventor: CHINEA SANTIAGO GLAY
IPC: A61P31/14
Filed: 2021-11-03
Abstract: The invention relates to a chimeric protein having a modular structure and comprising a coronavirus spike protein (S) receptor binding domain (RBD), a segment with hepatitis B virus nucleocapsid antigen (HBcAg) binding capacity, a segment comprising the amino acid sequence HHHHHH and two spacer segments. In the chimeric protein, the segments are arranged in a specific order and has the ability to form hybrid nanoparticles with the HBcAg. The chimeric protein forms part of vaccine compositions for the prevention of infections caused by coronavirus. Therefore, the invention relates to a method for preventing an infection caused by coronavirus wherein a vaccine composition comprising said chimeric protein is administered.
Patent AU-2021455895-A1 (AU)
Title: Refrigerating appliance with a door hinge
Inventor: FURLAN OMAR
IPC: F25D23/02
Filed: 2021-07-14
Abstract: Household appliance (2), especially refrigerating appliance, comprising a casing (4) with a door hinge (100), whereby said door hinge (100) comprises a hinge bracket (142) and a pin (148) which is inserted into a corresponding hinge seat (162) provided on said hinge bracket (142), whereby said pin (148) comprises an essentially cylindrical part (154) with two ends (170, 172) and a deformed part (158) arranged in between said two ends (170, 172) with a diameter larger than the diameter of said cylindrical main part (154).
Patent WO-2022183246-A1 (WO)
Inventor: KOLLMANN REINHARD TOBIAS
IPC: A61K31/198
Filed: 2022-03-03
Abstract: La présente invention concerne des compositions, des procédés et des kits pour le traitement et/ou la prévention et/ou le diagnostic de la septicémie. En particulier, les compositions, les procédés et les kits sont particulièrement utiles au traitement, à la prévention ou au diagnostic de la septicémie néonatale, sans s'y limiter. La présente invention concerne un procédé de diagnostic, de traitement ou 5 de prévention de la septicémie néonatale chez un patient en ayant besoin, le procédé comprenant l'administration au patient d'une quantité thérapeutiquement efficace d'un ou de plusieurs parmi un agoniste de Tie-2, de l'angiopoïétine-1 (Ang-1) ou un équivalent, analogue ou variant fonctionnel correspondant, de l'acide arachidonique (AA) de L-Arginine (L-Arg), un antagoniste de l'angiopoïétine-2 (Ang-2) ou une combinaison d'un agoniste de Tie-2, de l'angiopoïétine-1 (Ang-1) ou un équivalent fonctionnel, un analogue 0 ou un variant correspondant, de la L-Arginine, de l'acide arachidonique (AA), un antagoniste de l'angiopoïétine-2 (Ang-2), ce qui permet de traiter ou de prévenir une septicémie néonatale chez le patient.
Patent AU-2022200882-A1 (AU)
Title: Soft Pack Battery Module and its Electricity Supply Thereof
Inventor: YANG SZU-NAN
IPC: H01M50/136
Filed: 2022-02-10
Abstract: OF THE DISCLOSURE 
The invention provides a soft pack battery module and its electricity supply thereof.  
The battery units, which are independent and complete modules, are utilized to be 
contacted to each other to form the battery cell with the serial connection, the parallel 
5 connection or both. There only have charges transferred rather than electrochemical 
reactions occurred between the battery units. Also, the metallized plastic film package is 
utilized to pack the battery cell. The inner electrically-conductive area of the metallized 
plastic film package is directly contacted to the electric power outputs of the battery cell to 
form electrical connections. Therefore, the problems caused by the need for additional 
10 wires can be avoided and the surface area the current path of the battery cell can be 
maximized.  
17
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21 
23 
26 
25 
FIG. 1C
Patent AU-2022201780-A1 (AU)
Title: Microflow restrictor assembly and methods of making the same
Inventor: SCHINAZI ROBERT G
IPC: A61M5/14
Filed: 2022-03-15
Abstract: A medical fluid microflow assembly having an assembly fluid inlet and an assembly fluid 
outlet, and a mandrel having a curved exterior surface, the mandrel being positioned within an 
cavity of a housing so that the exterior surface of the mandrel is substantially parallel to an 
interior surface of the cavity, and at least one protrusion positioned helically around and 
extending from the interior surface of the cavity, each protrusion abutting the exterior surface of 
the mandrel to form a sealed fluid channel which has a channel inlet positioned proximate to the 
assembly fluid inlet and a channel outlet positioned proximate to the assembly fluid outlet, the 
exterior surface of the mandrel and the interior surface of the cavity having a minimal or neutral 
triboelectric value with respect to a fluid.
Patent AU-2022202988-A1 (AU)
Title: Single-step process for the production of a carbon fiber precursor
Inventor: FRANCALANCI FRANCO
IPC: D01D1/02
Filed: 2022-05-04
Abstract: SINGLE-STEP PROCESS FOR THE PRODUCTION OF A CARBON FIBER 
PRECURSOR" 
ABSTRACT 
An integrated and improved, single-step, process for the production of a carbon 
5 fiber precursor is described, specifically a process which starts from the 
comonomers and reaches the spinning step, obtaining the final precursor fiber.
Patent AU-2022204748-A1 (AU)
Title: Route planning for a ground vehicle through unfamiliar terrain
Inventor: ARMSTRONG KALANI A
IPC: G01C21/30
Filed: 2022-07-01
Abstract: ROUTE PLANNING FOR A GROUND VEHICLE THROUGH 
UNFAMILIAR TERRAIN 
ABSTRACT 
A method is provided for supporting one or more ground vehicles (106) on a mission that 
includes traversal of a ground region. The method includes accessing geospatial data produced 
from an aerial survey of the ground region, and performing an analysis of the geospatial data to 
produce terrain data (618, 718, 818) that describes the ground region. The terrain data (618, 718, 
818) is weighted based on constraints of the one or more ground vehicles (106), and an order of 
priority of criteria of the mission. A map is constructed in which the ground region is expressed 
as a geospatially-mapped array of the weighted terrain data, and the map is searched for a path 
that meets the criteria of the mission. The path is described by a series of waypoints that define a 
route across the ground region, and an indication of the route is output for the one or more 
ground vehicles (106) to traverse during the mission.
1/14 
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Patent AU-2022212857-A1 (AU)
Title: Machine Stand and Method of Supporting a Machine using a Stand
Inventor: ELBOURN ANDREW PHILLIP
IPC: F16M11/16
Filed: 2022-08-08
Abstract: In an aspect, there is disclosed a stand (10) for fitting with ajack tube (12) of a machine.  
The machine may be, but not limited to a tracked mining machine. The jack tube (12) 
may form part of a hydraulic jack assembly (13). The support stand (10) includes a 
body assembly (20) adapted to form a collar (22) in a fitted condition concentrically 
along at least of part of the jack tube 12. The collar (22) has an upper end (24) and a 
lower end (26) that are engageable with one or both of the jack tube (12) and machine 
so as to maintain the jack tube (12) in an extended condition. A related system and 
method are also disclosed.
Patent AU-2022221497-A1 (AU)
Title: Bearing assembly for a wheel unit
Inventor: CONNELL ALEX
IPC: F16C35/06
Filed: 2022-08-25
Abstract: A suspension system for a wheel of a vehicle includes a first arm, a second arm, a 
support structure positioned between the first arm and the second arm, a first bearing 
assembly coupled to the first arm and supporting the support structure for movement, and a 
second bearing assembly coupled to the second arm and supporting the support structure for 
movement. The support structure is configured to be coupled to the wheel that is rotatable 
about a wheel rotation axis. The first bearing includes a spherical bearing, and the second 
bearing assembly includes a first spherical bearing and a second spherical bearing.  
18993901_1 (GHMatters) P119815.AU
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Patent AU-2022229462-A1 (AU)
Title: Biochip for cryopreservation or thawing and resuscitation of biological tissue
Inventor: CHAN HO NAM
IPC: A01N1/02
Filed: 2022-03-01
Abstract: A biochip for cryopreservation or thawing and resuscitation of biological tissue, with four ends of the biochip being of a closed structure. The biochip comprises: a section region, which is arranged in the middle and comprises a plurality of sequentially arranged sections (11), with partition plates being provided between the sections (11), and the bottom of each section (11) being provided with a fixing groove (13); and joint portions (12) arranged on two sides of the section region. In the biochip having four ends being of a closed structure, a hydrogel or solution can be encapsulated in the plurality of sections of the biochip, such that the device is simple to operate and can effectively improve the efficiency of cryopreservation or thawing and resuscitation of embryos.
Patent AU-2022235325-A1 (AU)
Title: 3'3' cyclic dinucleotides containing isonucleotidic units
Inventor: BIRKUS GABRIEL
IPC: C07H19/11
Filed: 2022-03-01
Abstract: The present disclosure relates to 3'3' cyclic dinucleotides containing isonucleotidic units, their pharmaceutically acceptable salts, their pharmaceutical composition and combinations of said substances and other medicaments or pharmaceuticals. The disclosure also relates to the use of said compounds for the treatment or prevention of diseases or conditions modifiable by STING protein modulation, such as cancer or viral, allergic and inflammatory diseases. In addition, these substances can be used as adjuvants in vaccines. The compounds have formula (J):
Patent AU-2022259250-A1 (AU)
Title: Use of peptide amide compound in preparation of drug for treating pruritus
Inventor: WANG YONGRUI
IPC: A61K38/07
Filed: 2022-04-11
Abstract: Use of a compound represented by formula (I) or a stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt, eutectic, or a composition thereof in preparation of a drug for treating pruritus. Also provided is a method for treating pruritus, the method comprising administering an effective dose of the compound represented by formula (I) or the stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt, eutectic, or a composition thereof.
Patent AU-2022283262-A1 (AU)
Title: Compositions and methods for improved treatment of x-linked myotubular myopathy
Inventor: MILLER WESTON
IPC: A61P21/00
Filed: 2022-05-24
Abstract: The present invention provides methods for treating co-morbid cholestatic liver dysfunction (e.g., cholestasis and hyperbilirubinemia) associated with a neuromuscular disorder. In certain embodiments, the invention provides methods for assessing readiness of a subject with X-linked myotubular myopathy (XLMTM) for combination therapy with an anti-cholestatic agent.
Patent AU-2022289869-A1 (AU)
Title: Anticancer compounds
Inventor: SHIAU ANDREW
IPC: A61K31/33
Filed: 2022-06-08
Abstract: Disclosed are compounds of formula (I): formula (I) and pharmaceutically acceptable salts thereof. The compounds of the invention are BDII- selective inhibitors of BET proteins, and have therapeutic potential for treating cancer, acute kidney disease, and viral infections, among other diseases.
Patent AU-2022295130-A1 (AU)
Title: COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF α1-ANTITRYPSIN DEFICIENCY
Inventor: RAMSDEN NIGEL
IPC: A61K31/445
Filed: 2022-06-15
Abstract: The invention relates to pharmaceutical compositions comprising (S)-1-((2-(trifluoromethyl)phenyl)sulfonyl)piperidine-3-carboxylic acid and their medical use, for example for use in the treatment of α
Patent AU-2022348883-A1 (AU)
Title: High-precision positioning system for underground monorail hoist in coal mine and positioning method thereof
Inventor: LU HAO
IPC: B66C13/46
Filed: 2022-09-30
Abstract: The present disclosure discloses a high-precision positioning system for an underground 
monorail hoist in a coal mine and a positioning method thereof. The system comprises 
two gear carriers symmetrically arranged on both sides of an I-beam track. Each of the 
gear carriers is provided with a positioning wheel and a plurality of travelling wheels.  
The travelling wheels are travelling on an upper end face of a bottom plate of the I-beam 
track, and the positioning wheel is in engagement transmission with a rack at a lower end 
of the bottom plate of the I-beam track. The gear carriers are further provided with an 
installation bracket and a connecting seat configured to connect the monorail hoist. The 
installation bracket is provided with an inertial measuring unit and a single-chip 
microcomputer that are electrically connected with each other. The positioning wheel is 
provided with a rotation angle sensor and the rotation angle sensor is electrically 
connected to the single-chip microcomputer. A headstock at both ends of the monorail 
hoist is provided with a coordinate updating unit. The present disclosure utilizes the 
high-precision engagement between the positioning wheel and the track on the I-beam 
track, and then calculates the displacement of the positioning wheel to implement the 
high-precision positioning of the monorail hoist.
Patent WO-2023225719-A1 (WO)
Inventor: JIANG YUE
IPC: C01G23/00
Filed: 2023-05-26
Abstract: The present invention is directed to piezo photocatalytic process for the production of hydrogen from water, wherein the process comprises the steps of: (a) providing non-metal-doped barium titanate which includes at least one defect; (b) contacting the non-metal-doped barium titanate provided in step (a) with water to form a mixture; and (c) subjecting the mixture formed in step (b) to: (i) actinic radiation; and (ii) mechanical force, to produce hydrogen from the water, as well as non-metal-doped barium titanate and methods of production thereof.
Patent WO-2024011283-A1 (WO)
Inventor: KRUGER ULI
IPC: B24C3/14
Filed: 2023-07-11
Abstract: L'invention concerne une surface portante combinant les avantages de dispositifs de dynamique des fluides à la fois de type de portance et de pression dans laquelle la surface inférieure se présente sous la forme d'une hyperbole convexe vers le bord d'attaque et d'une hyperbole concave symétrique vers le bord de fuite, ce qui permet d'obtenir une portance accrue sans affecter négativement la finesse aérodynamique.
Patent AU-2023200394-A1 (AU)
Title: A Method for the Preparation of Alumina
Inventor: ATKINS ANNETTE MARGARET
IPC: C01F1/00
Filed: 2023-01-25
Abstract: A method for the preparation of alumina, the method comprising the steps of: 
treating aluminous material to increase the alumina content to over about 
30 %; 
treating the aluminous material to provide particle size less than about 0.5 
mm; 
calcining the aluminous material at about 400 - 700 °C; 
treating the aluminous material to provide particle sizes less than about 
500 pm; 
leaching the aluminous material with a mineral acid to provide a pregnant 
liquor; 
conducting a plurality of steps of precipitating aluminium chloride 
hexahydrate; 
conducting a plurality of ion exchange steps; and 
calcining aluminium chloride hexahydrate to provide alumina.
Patent AU-2023200517-A1 (AU)
Title: Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same
Inventor: WEINER DAVID B
IPC: C07H21/00
Filed: 2023-02-01
Abstract: Provided herein are consensus amino acid sequences of prostate antigens that are capable of breaking 
tolerance in a targeted species, including PSA, PSMA, STEAP and PSCA antigens. Also provided are 
nucleic acid sequences that encode one or more consensus amino acid sequences of prostate antigens 
PSA, PSMA, STEAP and PSCA, as well as genetic constructs/vectors and vaccines expressing the 
sequences. Also provided herein are methods for generating an autoimmune response against prostate 
cancer cells by administering one or more of the vaccines, proteins, and/or nucleic acid sequences that 
are provided.
Patent AU-2023201642-A1 (AU)
Title: Method and System for Dispatching Casino Personnel and Tracking Interactions with Players
Inventor: ACRES JOHN F
IPC: G07F17/32
Filed: 2023-03-15
Abstract: METHOD AND SYSTEM FOR DISPATCHING CASINO 
PERSONNEL AND TRACKING INTERACTIONS WITH PLAYERS 
ABSTRACT OF THE DISCLOSURE 
The present embodiment includes a dispatch system and method in which a casino agent is 
equipped with mobile computing devices that receive a dispatch notification. The notification 
includes the identity of an electronic gaming device at which an identified player has started a 
gaming session and the identity of the player. The player's record is displayed on the mobile 
computing device and includes the number of times the casino agent has been dispatched to a 
gaming device at which the player is identified as well as descriptions of prior calls.  
Attorney's Docket No. 1351-0486
Patent AU-2023201727-A1 (AU)
Title: Vessel Treatment Systems, Methods, And Kits
Inventor: AUSTEN WILLIAM G
IPC: A01N1/02
Filed: 2023-03-20
Abstract: One aspect of the invention provides a vessel treatment system including: a housing 
defining at least one opening adapted and configured to receive an anatomical vessel; and a 
humidifier in communication with the housing, the humidifier adapted and configured to 
introduce humidity into the housing to prevent desiccation of the anatomical vessel. Another 
aspect of the invention provides a kit including: the vessel treatment system as described 
herein; and a passivation agent. Another aspect of the invention provides a method for 
preparing a vein graft. The method includes: applying a tissue passivation agent to a resected 
anatomical vessel; and placing the resected anatomical vessel in a humidified chamber while 
the tissue passivation agent cures.
Patent AU-2023202433-A1 (AU)
Title: An Accessory for a Vehicle
Inventor: NIELSEN JAKE ARTHUR
IPC: B60P3/36
Filed: 2023-04-20
Abstract: A accessory for a vehicle, the accessory being movable relative to the vehicle between a 
storage condition in which the accessory is received within a body of the vehicle and an 
extended condition in which the accessory is located at least partly externally to the body of 
the vehicle at a first height, wherein at least a portion of the accessory is configured for 
movement between the extended condition and a use condition located at a second height, the 
second height being below the first height.
5/6 
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FIG 9 
10 
28 
32 
FIG 10
Patent WO-2010115255-A1 (WO)
Title: Aeronave de deslocamento aéreo decolagem e pouso vertical
Inventor: BRUSTOLIN JAIME
IPC: B64C29/00
Filed: 2010-04-07
Abstract: Aeronave de deslocamento aéreo decolagem e pouso vertical, para locomoção aérea de formato circular, com anéis onde é montada a cabine e a estrutura fixa da nave (1). Anel horizontal (3) junto com o rotor (9), lâminas de sustentação (5) e anel móvel (27), é o conjunto que gira e suspende a nave com toda a estrutura das hastes (8A) (8B), movida a energia das baterias que situadas dentro da cabine (98) e na ponta das lâminas (19). O rotor gira encostado em rolamentos verticais (21), rolamentos horizontais (54) e rolamentos das pontas das lâminas que atuam na sustentação destas lâminas que atuam na sustentação da nave (44). Na coroa externa vazada (17), estão os lemes móveis de controle de torque (51) e os lemes fixos na coroa (50). Para o avanço e recuo, como direita e esquerda (72), mais coroa, lâmina giratória estabilizadora (55) com folhas desviadoras de ar (114).
Patent WO-2013177643-A1 (WO)
Inventor: INGO HEINZ STAHLHOEFER BERGMANN
IPC: E04H5/04
Filed: 2013-05-28
Abstract: The present invention relates to a modular electrical enclosure comprising at least two modules, each module having at least one joining side without walls, and the modules being joined at the respective joining sides. In a configuration suitable for hoisting, each module is provided with hoisting points located on the outer beams of the covering structure. For at least one hoisting point located in a joining side, between the outer vertical beams, at least one removable intermediate beam is provided; the lower end of the removable intermediate beam is attached to an outer beam of the main structure, and the upper end of the removable intermediate beam is attached to an outer beam of the covering structure. In the finished assembled configuration, none of the joining sides is provided with removable intermediate beams. According to the invention, when the modules are manufactured, the removable intermediate beams are attached to the structure of the modules. These removable intermediate beams fulfill a structural function, allowing the modules to be hoisted for being moved and transported. Once the modules have been transported to the working site and assembled, forming the final assembled configuration of the modular electrical enclosure, the removable intermediate beams are removed. Thus, the common inside region of the modular electrical enclosure is completely free of inner pillars.
Patent WO-2015095947-A1 (WO)
Title: Concentré de cellules souches immunocompatibles et multipotentes
Inventor: KERKIS ALEXANDRE
IPC: C12N5/0775
Filed: 2014-12-22
Abstract: La présente invention concerne de manière générale un concentré de cellules souches isolé à partir d'un tissu adipeux vascularisé de mammifère, des produits biopharmaceutiques contenant ledit concentré et leur utilisation dans des thérapies pour le traitement de maladies chez les mammifères.