baber/WOPTO huggingface dataset:
Patent DE-69720428-D1 (DE)
Inventor: KHANNA K
IPC: A61K31/422
Filed: 1997-01-24
Granted: 2003-05-08
Abstract: A process to make a compound of the formula <CHEM>  or a pharmaceutically acceptable salt thereof is disclosed wherein R<3> is a radical selected from hydrido, alkyl, haloalkyl, aralkyl, heterocycloalkyl, heteroaralkyl, acyl, cyano, alkaxy, alkylthio, alkylthioalkyl, alkylsulfonyl, cycloalkylthio, cycloalkylthioalkyl, cycloalkylsulfonyl, cycloalkylsulfonylalkyl, haloalkylsulfonyl, arylsulfonyl, halo, hydroxyalkyl, alkoxyalkyl, alkylcarbonyl, arylcarbonyl, aralkylcarbonyl, heterocyclocarbonyl, cyanoalkyl, aminoalkyl, alkylaminoalkyl, N-arylaminoalkyl, N-alkyl-N-arylaminoalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxycarbonyl, haloalkylcarbonyl, carboxyl, aminocarbonyl, alkylaminocarbonyl, alkylaminocarbonylalkyl, heteroarylalkoxyalkyl, heteroaryloxyalkyl, heteroarylthioalkyl, aralkoxy, aralkylthio, heteroaralkoxy, heteroaralkylthio, heteroarylalkylthioalkyl, heteroaryloxy, heteroarylthio, arylthioalkyl, aryloxyalkyl, arylthio, aryloxy, aralkylthioalkyl, aralkoxyalkyl, aryl and heteroaryl; wherein R<4> is a radical selected from hydrido, alkyl and halo; and wherein R<2> is selected from aryl and heterocyclo, wherein R<2> is optionally substituted at a substitutable position with one or more radicals independently selected from alkylsulfonyl, aminosulfonyl, halo, alkylthio, alkyl, cyano, carboxyl, alkoxycarbonyl, haloalkyl, hydroxyl, alkoxy, hydroxyalkyl, alkoxyalkyl, haloalkoxy, amino, alkylamino, arylamino and nitro; said method comprising the steps of forming a (protected sulfonyl)benzenamine, treating said (protected sulfonyl)benzenamine first with a base and then with a nitrile to form an amidine, treating said amidine with a haloketone derivative in the presence of a base to form a hydroxyimidazole, forming a (protected sulfonylphenyl) imidazole by dehydrating said hydroxyimidazole, and forming said compounds by deprotecting said (protected sulfonylphenyl)imidazole.
Patent DE-69737980-D1 (DE)
Inventor: GARVEY DAVID S
IPC: A61K31/00
Filed: 1997-01-28
Granted: 2007-09-13
Abstract: Disclosed are nitrosated and nitrosylated  alpha -adrenergic receptor antagonists, compositions of an  alpha -adrenergic receptor antagonist ( alpha -antagonist), which can optionally be substituted with at least one NO or NO2 moiety, and a compound that donates, transfers or releases nitric oxide as a charged species, i.e., nitrosonium (NO+) or nitroxyl (NO-), or as the neutral species, nitric oxide (NO+574 ); and uses for each of them in treating human male impotence or erectile dysfunction.
Patent DE-69739453-D1 (DE)
Inventor: MITRA DEBASIS
IPC: H04L12/56
Filed: 1997-02-04
Granted: 2009-07-30
Abstract: A method shares resources associated with various classes among calls in the various classes according to a state dependent reservation parameter. Nominal amounts of one or more resources are allocated to each call class. When a call of a class of service operating in a network requires resources in excess of those allocated to the class, resources allocated to other classes of service are advantageously shared with the class of service. The sharing is based on a reservation parameter associated with the class of service of the call. The reservation parameter is advantageously a function of the network state. The role of the reservation parameter is to protect underloaded classes (i.e., those classes not using all of their allocated nominal capacity) from excessive borrowing by overloaded classes ( i . e ., classes using more than their allocated nominal capacity). More generally, the inventive method is used to determine if sufficient resources are available for routing calls and to route calls based on the determined available resources.
Patent DE-69800749-D1 (DE)
Inventor: ORSI MARCO
IPC: A01G31/02
Filed: 1998-06-09
Granted: 2001-06-07
Abstract: PCT No. PCT/EP98/03441 Sec. 371 Date Feb. 3, 1999 Sec. 102(e) Date Feb. 3, 1999 PCT Filed Jun. 9, 1998 PCT Pub. No. WO98/56237 PCT Pub. Date Dec. 17, 1998A modular structure for aeroponic cultivations comprising a plurality of prefabricated side panels which are meant to receive plants being cultivated and a plurality of prefabricated flat bases to which the side panels are joined by means of respective interlock couplings in order to form a structure which is substantially shaped like an inverted V and in which the side panels are mutually connected along an upper ridge line by respective ridgecaps; a pumping unit and a spraying apparatus are also provided in order to feed an atomized nutrient solution inside the structure.
Patent DE-69806408-D1 (DE)
Inventor: CURTISS III
IPC: A61K39/00
Filed: 1998-11-13
Granted: 2002-08-08
Abstract: Attenuated immunogenic bacteria having an RpoS<SUP>+</SUP> phenotype, in particular, Salmonella enterica serotype Typhi having an RpoS<SUP>+</SUP> phenotype and methods therefor are disclosed. The Salmonella have in addition to an RpoS<SUP>+</SUP> phenotype, an inactivating mutation in one or more genes which render the microbe attenuated, and a recombinant gene capable of expressing a desired protein. The Salmonella are attenuated and have high immunogenicity so that they can be used in vaccines and as delivery vehicles for genes and gene products. Also disclosed are methods for preparing the vaccine delivery vehicles.
Patent DE-69811105-D1 (DE)
Inventor: DUAN YONGJUN
IPC: A61K9/16
Filed: 1998-10-27
Granted: 2003-03-06
Abstract: The invention is a method of administering therapeutic iodine for treating a disorder in a mammal. The invention comprises a step of feeding said mammal an effective amount of an oxidant for an iodine species and an iodine reductant which will cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of the mammal. This is done such that molecular iodine is generated in vivo at a ratio of molecular iodine to total iodine of above at least about 0.65. The invention also discloses a non-aqueous pharmaceutically acceptable carrier with said oxidant and reductant having the ability to cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of said mammal and in an amount sufficient to generate molecular iodine, in vivo, at a ratio of molecular iodine to total iodine of above at least about 0.65.
Patent DE-69815464-D1 (DE)
Inventor: BOUSSIGNAC GEORGES
IPC: A61M16/00
Filed: 1998-10-26
Granted: 2003-07-17
Abstract: The tubular respiratory assistance apparatus comprises a main channel linked by its distal end to the airway of a patient It also has at least one auxiliary channel associated with a deflector used for injecting a jet of respiratory gas into the main channel and then to ventilate the patient. On its distal side the tubular component is surrounded by an annular chamber which is connected to the patient's respiratory system via an orifice and has a branch linking the chamber's proximal end to the outside atmosphere. An Independent claim is also included for an assisted respiratory mask for application to the face of a patient comprising a nozzle for the inlet and outlet of the respiratory gas, and the apparatus is as above.
Patent DE-69816367-D1 (DE)
Inventor: OHUCHIDA SHUICHI
IPC: C07C311/00
Filed: 1998-05-14
Granted: 2003-08-21
Abstract: Benzenesulfonamide compounds of formula (I) <CHEM> (R<1> is hydroxy, C1-4 alkoxy, NR<6>R<7> (each R<6> and R<7> is, independently, H or C1-4 alkyl); R<2> is H, C1-4 alkyl; R<3>, R<4> are C1-4 alkyl, halogen, trifluoromethyl; R<5> is H, C1-4 alkyl, halogen, trifluoromethyl; Y is cis-vinylene, trans-vinylene; and the symbol <CHEM> is single bond, double bond) can bind strongly to the EP1 receptor which is a prostaglandin E2 receptor subtype and scarcely bind to the other receptor subtypes. Therefore, they are considered to be useful as antipyretic agents, as analgesics or as agents for the prevention and/or treatment of pollakiuria having little side effect.
Patent DE-69819026-D1 (DE)
Inventor: GAMBA WILLIAM
IPC: A61K8/22
Filed: 1998-01-22
Granted: 2003-11-20
Abstract: The method, belonging to the aesthetical field, intends to prevent hair loss and to stimulate the natural growth of hair in bald areas by restoring a valid micro-circulation into the scalp (both at cutaneous and subcutaneous level), thanks to the injection of an oxygen-ozone mixture. As for the oxygen-ozone mixture, the concentration can vary from 1 (one) microgram O3/ml.O2 to 40 (fourty) micrograms O3/ml.O2, while the quantity can vary from 5 (five) to 60 (sixty) cubic centimetres.
Patent DE-69826789-D1 (DE)
Inventor: WALKUP N WAYNE
IPC: A23L3/015
Filed: 1998-07-31
Granted: 2004-11-11
Abstract: A process for sterilization of a liquid in a continuous system comprising a series of steps. First the liquid is continuously pumped into a pressurized system. Second, the pressure on the liquid is increased in a first pressurization stage. Next, the liquid is increased in pressure in a second pressurization stage. Fourth, the liquid is held at an elevated pressure for a predetermined period of time to kill off microorganisms within the liquid. The liquid is then rapidly depressurized to fracture microorganisms within the liquid. The apparatus for producing this process includes a continuous liquid treatment system with a pump, a first stage intensifier, a surge drum, a second stage intensifier, a pressure receiver and a pressure reducer. A particulate treatment system may also be included which comprises a pressure receiver, an intensifier, and a recoverer for blending a particulate component with the liquid component. <IMAGE>
Patent DE-69827621-D1 (DE)
Inventor: MICHAELI DOV
IPC: C07K14/72
Filed: 1998-05-12
Granted: 2004-12-23
Abstract: The invention concerns immunogens, immunogenic compositions and method for the treatment of gastrin-dependent tumors. The immunogens comprise a peptide from the CCK-B/gastrin-receptor conjugated to a spacer and to an immunogenic carrier. The immunogens are capable of inducing antibodies in vivo which bind to the CCK-B/gastrin-receptor in tumor cells, thereby preventing growth stimulating peptide hormones from binding to the receptors, and inhibiting tumor cell growth. The immunogens also comprise antibodies against the CCK-B/gastrin-receptor for passive immunization. The invention also concerns diagnostic methods for detecting gastrin-dependent tumors in vivo or from a tissue biopsy using the antibodies of the invention.
Patent DE-69832405-D1 (DE)
Inventor: TOSKALA ANTTI
IPC: H04B7/005
Filed: 1998-09-09
Granted: 2005-12-22
Abstract: The invention relates to a method of implementing macrodiversity in a cellular radio network having in each cell at least one base station which communicates with subscriber terminals within its area. Packet switched connections are provided between the base station and the terminals, the connections comprising an actual traffic channel and a separate control channel. In signal transmission, the terminals use IQ modulation in which the traffic and control channels are multiplexed to be transmitted on different branches, and the terminals can communicate with more than one base station simultaneously. To enable macrodiversity in packet switched connections, the actual traffic channel connection is also maintained between the terminal and only one base station, and the control channel connection is maintained between the terminal and more than one base station simultaneously.
Patent DE-69835816-D1 (DE)
Inventor: HOTTINEN ARI
IPC: H04B1/707
Filed: 1998-06-23
Granted: 2006-10-19
Abstract: The invention relates to a reception method and a receiver in a system comprising in each cell a base station communicating with terminals located in its area. A received signal comprises a sum signal of signals originating from several transmitters. The receiver comprises means for performing interference elimination and a simultaneous multi-user detection to the signal and means for searching signal parameters. In order to reduce the required computational capacity, the receiver further comprises means for removing the effect of the signals of the known users from the receives sum signal, and means for estimating the parameters of the unknown signals from a narrowband residual signal.
Patent DE-69837529-D1 (DE)
Inventor: HANASH SAMIR M
IPC: A61K39/00
Filed: 1998-02-12
Granted: 2007-05-24
Abstract: Computerized analysis of 2-D gels, both carrier ampholyte (CA) and immobilized pH gradient (IPG) based, of the proteins in tissue from lung tumors, reveals proteins which are different in different types of tumors and in control tissues.
Patent DE-69904701-D1 (DE)
Inventor: YAMAGATA YUTAKA
IPC: A61K9/16
Filed: 1999-03-18
Granted: 2003-02-06
Abstract: A method for producing a sustained-release preparation, which comprises dispersing a physiologically active polypeptide into an organic solvent solution of a biodegradable polymer and removing the organic solvent, wherein the polypeptide is a powder obtained by lyophilizing an aqueous solution of the polypeptide which solution has a water-miscible organic solvent and/or a volatile salt; which improves the ease of handling of the physiologically active polypeptide powder in the process for producing the preparation; which makes it possible to industrially produce the sustained-release preparation in large scale; which provides a sustained-release preparation showing high and stable concentration of the active component in blood in long term, low initial release ratio of the physiologically active polypeptide, and high entrapment ratio of the polypeptide into the sustained-release preparation.
Patent DE-69905052-D1 (DE)
Inventor: VAN DER LAAN MARKUS
IPC: B63B21/56
Filed: 1999-08-24
Granted: 2003-02-27
Abstract: An emergency towing system for vessels. This system comprises a return guide fitted to the vessel to be towed; a closed ring-cable is fitted around this return guide, wherein this ring-cable comprises a coupling-member which, when the ring-cable is heaved around, establishes a connection with a contra-coupling-member on the vessel to be towed.
Patent DE-69913016-D1 (DE)
Inventor: VAN DER PLOEG EVERT
IPC: G05D1/02
Filed: 1999-03-16
Granted: 2004-01-08
Abstract: The invention relates to an apparatus (1) for cleaning a stable, comprising a cleaning slide (2) which, during use is arranged such as to be movable in the aisle (3) of a cattle shed (4), and which is provided with a control unit (8) and a motor drive for moving, under control of the control unit, the cleaning slide in the aisle, the control unit (8) being connected with sensor means (7) and the control unit (8) comprising control logic for emitting a sensor means-dependent control signal to the motor drive. The apparatus for cleaning a stable is equipped as an autonomically movable vehicle (1) onto which the cleaning slide (2) is mounted, and which is provided with wheel members (5,6), at least one (6) of which wheels being adjustable for determining the vehicle's direction, that the vehicle (1) is provided with means (7) for determining its position in the cattle shed (4), and that the control unit (8) is equipped with a memory for storing data about the cattle shed (4), the position of the vehicle (1) in the cattle shed (4), and a plan of the route along which the vehicle (1) is to move in the cattle shed (4). <IMAGE>
Patent DE-69922401-D1 (DE)
Inventor: DOKHELAR MARC
IPC: A01G9/02
Filed: 1999-09-02
Granted: 2005-01-05
Abstract: The invention concerns a device for replacing trees, shrubs and flowers and for tending them. More particularly, it concerns a device for transplanting plants, comprising a buried cylindrical receptacle (1), wherein is inserted a container (2) bearing the plant roots and whereof the base is mounted on geotextile fabrics (4) supported by a segment (3). The plant is irrigated by capillary effect. A removable reservoir (5) inserted through the upper base of the receptacle (1) is set beneath the container (2), a fabric (6) immersed in the reservoir (5) provides the plant with water. A removable device placed beneath the reservoir (5) increases the volume of water and regulates the flow according to climatic conditions. It comprises three springs (11) fixed at their base to a tray (12) adjustable in height by threads (16) which maintain the reservoir (5) by their upper base. An elastic ring (14) enables to fix and seal a mulching material (15). The invention is particularly useful for embellishing parks, gardens and apartments.
Patent DE-69924588-D1 (DE)
Inventor: COULTHARD MARTIN
IPC: G01N21/88
Filed: 1999-12-10
Granted: 2005-05-12
Abstract: An automatic inspection apparatus is provided in which a camera (14) is simultaneously arranged to receive light reflected from an item under test (6) and to view the light source (2) such that the apparatus can monitor both the light source and reflected light in order to obtain reliable measurements of surface and/or colour properties. <IMAGE>
Patent DE-69925848-D1 (DE)
Inventor: PARAVISI MARCO
IPC: F16D65/02
Filed: 1999-12-16
Granted: 2005-07-21
Abstract: A safety device for support pins for pads of vehicle brake calipers, particularly for disk brakes, in which at least one support pin (38) is supported removably by a caliper element (30) which is intended to hold the pads, and which has means (1) which can be associated removably with the support pin (38) to prevent the support pin (38) from slipping out of the caliper element (30) comprises, for each support pin (38), a respective clip (4) with an eye (7) which can be mounted astride the support pin (38) so as to extend around it, the pin support (38) having abutment means for preventing relative axial sliding of the clip (4) on the support pin (38) in at least one direction, so as to oppose slipping of the support pin (38) out of the caliper element (30). <IMAGE>   <IMAGE>
Patent DE-69926143-D1 (DE)
Inventor: JORGENSEN A
IPC: F16D27/118
Filed: 1999-12-02
Granted: 2005-08-18
Abstract: The present application discloses a power actuator that has a motor having a rotatable motor output member and a clutch assembly. A stamped, cup-shape ferromagnetic coil casing has a generally radially extending base wall and an annular side wall extending generally axially from the base wall. An annular ferromagnetic flux intensifying washer is positioned adjacent to the base wall of the coil casing. An annular coil of electroconductive material is disposed within the casing with the side wall extending in surrounding relation with respect to the coil such that the field generated by the coil flows generally radially through the base wall and generally axially through said side wall. A ferromagnetic armature is in sliding relation with the annular coil and movable between an engaged position and a disengaged position.
Patent DE-69927255-D1 (DE)
Inventor: KHOSRAVI M JAVAD
IPC: G01N33/543
Filed: 1999-03-08
Granted: 2005-10-20
Abstract: A method of assaying the growth hormone status of an individual by immuno-assay for the 150 KDa Insulin-like Growth Factor ternary complex (IGF/IGFBP-3/ALS). Alternatively, a binary complex may be assayed. The method involves capturing the IGFBP complex with a first antibody coupled to a solid phase and detecting the complex with a second antibody coupled to a label. A set of monoclonal and polyclonal antibodies usefutl for the assay is also provided.
Patent DE-69936898-D1 (DE)
Inventor: COOGAN JOHN
IPC: E21B44/02
Filed: 1999-12-07
Granted: 2007-09-27
Abstract: The invention relates to and a rock drilling equipment. The rock drilling equipment comprises a carrier (1), a boom (4) attached turnable about joints (2,3,6.7) in relation to the carrier, a rock drill (10) attached turnable to the other end of the boom (4), joint sensors indicating the positions of the various boom joints, and control devices for controlling the boom to the drilling position for drilling a hole. The rock drilling equipment includes a memory device. The memory device is adapted to store the deviations between the true position of the boom (4) and the theoretical position calculated on the basis of the joint sensor values as a function of the turning angle (±) of at least one boom joint. A calculating device is provided for correcting the boom position on the basis of the deviations stored in the said memory device and corresponding to the value indicated by the joint sensor of the said joint.
Patent DE-69938148-D1 (DE)
Inventor: GABIZON ALBERTO A
IPC: A61K47/34
Filed: 1999-12-17
Granted: 2008-03-27
Abstract: A composition for administration of a therapeutic compound to a multi-drug resistant cell in a person suffering from a drug-resistant cancer is described. The composition is composed of a carrier molecule and a folate targeting ligand, which is covalently attached to the carrier, and the therapeutic compound. In one preferred embodiment, the carrier is a liposome having a surface coating of hydrophilic polymer chains where a folate ligand is attached to the free distal end of at least a portion of the hydrophilic polymer chains, and the therapeutic agent is entrapped in the liposomes. The composition is effective to achieve accumulation of the therapeutic compound in the cell in an amount sufficient to be cytotoxic. Also described are methods for administering a therapeutic compound to a person suffering from a multi-drug resistant condition.
Patent DE-69941540-D1 (DE)
Inventor: IKUDOME KOICHIRO
IPC: G06F15/00
Filed: 1999-04-29
Granted: 2009-11-26
Abstract: A data redirection system for redirecting user's data based on a stored rule set. The redirection of data is performed by a redirection server, which receives the redirection rule sets for each user from an authentication and accounting server, and a database. Prior to using the system, users authenticate with the authentication and accounting server, and receive a network address. The authentication and accounting server retrieves the proper rule set for the user, and communicates the rule set and the user's address to the redirection server. The redirection server then implements the redirection rule set for the user's address. Rule sets are removed from the redirection server either when the user disconnects, or based on some predetermined event. New role sets are added to the redirection server either when a user connects, or based on some predetermined event.
Patent DE-69941961-D1 (DE)
Inventor: FUKUSHIMA MASAKAZU
IPC: C12N15/06
Filed: 1999-08-31
Granted: 2010-03-11
Abstract: This invention relates to an anti-human thymidylate synthase monoclonal antibody capable of recognizing an epitope which exists in a region of from an N-terminus to a 61 st amino acid in human thymidylate synthase, and also hybridomas capable of producing these monoclonal antibodies.  These monoclonal antibodies are useful for the immunological measurement of human thymidylate synthase.
Patent DE-69942322-D1 (DE)
Inventor: GARBER SHARON R
IPC: H01Q1/22
Filed: 1999-08-05
Granted: 2010-06-10
Abstract: The present invention relates to RFID devices, including handheld RFID devices, and applications for such devices. The devices and applications may be used in connection with items that are associated with an RFID tag, and optionally a magnetic security element. The devices and applications are described with particular reference to library materials such as books, periodicals, and magnetic and optical media.
Patent DE-502004008904-D1 (DE)
Inventor: THEELEN NORBERT
IPC: B21B31/18
Filed: 2004-07-24
Abstract: Process for axially positioning rollers (1) in a roll stand (2) having at least three rollers comprises measuring the actual position of the roller shafts of the rollers integrated in the roll stand, determining the central point (M) of the box groove (9) and the actual shaft middle positions based on the intersection point of the measured roller shafts, and forming theoretical positions by the geometric relationship for the axial position of stopping surfaces (8) adjustable in the roll stand for each roller. An independent claim is also included for a roll stand.