baber/WOPTO huggingface dataset:
Patent DE-69431664-D1 (DE)
Inventor: COX D
IPC: C01F7/785
Filed: 1994-08-04
Granted: 2002-12-12
Abstract: An aggregated synthetic hydrotalcite having a substantially spheroidal shape and an average diameter of up to about 60  mu m is disclosed. The aggregates are composed of individual platy particles having plate diameters of from about 0.05 to about 10  mu m. The material has a low tapped density, a high pore volume and a high specific surface area. A process for producing the product is also disclosed. Product particle size is determined by controlling process parameters including reaction temperature and pH, stirring speed of the reaction mixture, and reactant addition rates and concentrations, including aqueous solutions of soluble magnesium and aluminum salts, which are mixed in a molar ratio of from about 2.5:1 to 4:1, and a basic solution containing excess carbonate and base to maintain the reaction mixture at a pH of from about 8.5 to about 9.5.
Patent DE-69500758-D1 (DE)
Inventor: AICHER THOMAS D
IPC: C07D498/04
Filed: 1995-09-11
Granted: 1997-10-30
Abstract: The invention concerns oxazole and thiazole compounds of formula <CHEM> where the substituents have various significances, in free form or salt form as appropriate. They can be prepared e.g. by coupling or hydrolysis. The compounds can be used as pharmaceuticals, especially as hypoglycemic agents in the treatment of diabetes.
Patent DE-69504044-D1 (DE)
Inventor: NILSON BILLY
IPC: B05B11/06
Filed: 1995-01-24
Granted: 1998-09-17
Abstract: PCT No. PCT/SE95/00065 Sec. 371 Date Nov. 12, 1996 Sec. 102(e) Date Nov. 12, 1996 PCT Filed Jan. 24, 1995 PCT Pub. No. WO95/25051 PCT Pub. Date Sep. 21, 1995A device for dispensing a flowable substance, which includes a rigid open channel or basin-shaped first main part having a dispensing channel with a dispensing opening, and a basin- or channel-like second main part which is comprised of a resilient material and has a shape complementary to the first main part, wherein the first main part and the second main part are joined together to form a closed dispensing container, and wherein the second main part has an end wall that includes a closure part which is complementary to the dispensing channel of the first main part and which lies resiliently against the dispensing opening. Pressure applied to the upper part of the end wall causes it to pivot on pivot points causing the closure part to swing upwardly and open the dispensing opening to permit discharge of the substance.
Patent DE-69504758-D1 (DE)
Inventor: NAKANISHI EIICHI
IPC: B23D51/16
Filed: 1995-06-09
Granted: 1998-10-22
Abstract: A mechanism for a cutting or grinding tool for converting rotational movement into reciprocating movement contains a casing (30), a reciprocating member (3) mounted within the casing (30) for receiving and securing a tool (40) to be inserted into a tool receiving opening (3b) of the reciprocating member (3), a shaft member (1) rotatably mounted within the casing (30) for rotation by a rotational driving force, a bearing member (8) for rotatably carrying the shaft member (1), and a support member (4, 6, 7) for carrying the reciprocating member (3) for enabling reciprocating movement thereon. The reciprocating member (3) and the shaft member (1) are spaced apart so that a center axis (3') of the reciprocating member (3) and a center axis (1') of the shaft member (1) are offset. A connecting member (2) is provided between the shaft member (1) and the reciprocating member (3) for interconnecting the shaft and reciprocating members (1, 3) for converting rotational movement of the shaft member (1) into reciprocating movement of the reciprocating member (3). One end (2i) of the connecting member (2) is slidably received and mounted in the shaft member (1) at a position offset from the axis (1') of the shaft member (1) and the other end (2f) of the connecting member (2) is slidably received and mounted in the reciprocating member (3) at a position offset from the axis (1') of the shaft member (1). <IMAGE>
Patent DE-69521939-D1 (DE)
Inventor: DUBIN MICHEL
IPC: G01R21/133
Filed: 1995-05-19
Granted: 2001-09-06
Abstract: A device for measurement of electrical energy having current and voltage sensors 1, 2, a multiplexing circuit 8 and an analogue to digital converter 11. A microprocessor 9 controls the multiplexing circuit in order to supply the current and voltage signals alternately to the converter 11, the microprocessor 9 calculating the electrical energy at a moment in time using two values of the voltage situated around a current sample and using three samples of the current. By these means the time delay between samples of the voltage and current can be corrected. <IMAGE>
Patent DE-69524641-D1 (DE)
Inventor: GRIFFIN ROGER JOHN
IPC: C07D263/57
Filed: 1995-03-09
Granted: 2002-01-24
Abstract: A range of quinazolinone compounds are disclosed which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-damaging cytotoxic drugs or radiotherapy to potentiate the effects of the latter. The compounds disclosed comprise certain quinazolinone compounds having the general structural formula II or pharmaceutically acceptable salt thereof,characterised in thatX' represents hydroxyl, alkyl, alkoxy or an optionally substituted aryl (e.g. phenyl) or aralkyl (e.g. benzyl) group,andY' represents hydrogen, alkyl or an optionally substituted aryl (e.g. phenyl) or aralkyl (e.g. benzyl) group.
Patent DE-69531289-D1 (DE)
Inventor: FEINGOLD VLADIMIR
IPC: A61F9/013
Filed: 1995-11-17
Granted: 2003-08-21
Abstract: An intraocular lens injection system comprising an injecting device and cartridge. The cartridge comprises a lens holding portion and an outer sleeve portion. The invention includes a method of pre-loading the injecting system, particularly the cartridge, to reduce the amount of packaging, prevent damage to the intraocular lens during packaging and shipping, allow the pre-loaded injecting cartridge to be autoclaved as a unit, and eliminate the step of loading the cartridge with the intraocular lens by the end user to prevent potential damage during this step.
Patent DE-69535452-D1 (DE)
Inventor: DEJACO ANDREW P
IPC: G10L25/78
Filed: 1995-08-01
Granted: 2007-05-16
Abstract: A method of adding hangover frames to a plurality of frames encoded by a vocoder, the method comprising: detecting that a predefined number of successive frames has been encoded at a first rate; determining that a next successive frame should be encoded at a second rate that is less than the first rate; and selecting a number of successive hangover frames beginning with the next successive frame to encode at the first rate, the numbering dependent upon an estimate of a background noise level.
Patent DE-69600258-D1 (DE)
Inventor: BENMALEK MOHAMED
IPC: C25D5/34
Filed: 1996-01-31
Granted: 1998-06-04
Abstract: A wear-resistant coating of Ni containing solid particles, e.g. of SiC, is applied to an Al or Al alloy surface subject to high friction by three stages. The Al is activated in a bath containing a Ni halide while acting as the anode in an electric circuit, then suractivated in a second chemical bath and finally immersed in a plating bath containing solid particles while acting as a cathode.
Patent DE-69601207-D1 (DE)
Inventor: KENNEDY BRIAN
IPC: G06Q10/06
Filed: 1996-06-10
Granted: 1999-02-04
Abstract: A strategy driven planning system (10) is provided that includes a plan (14) defining a scheduled operation of a user environment. An environment (16) defines behavior and constraints of the user environment. A plurality of strategies (20) each defining a plan domain (22), problem selection criteria (24), plan optimality criteria (28), and termination criteria (32). A planning engine (12) is coupled to the plan (14), the plurality of constraints (16) and the plurality of strategies (20). The planning engine (12) is operable to identify a plurality of problems (18) by comparing the plan (14) to the behavior and constraints defined by the environment (16) and is operable to adjust the plan (14) according to a selected strategy. A user interface (28) is coupled to the planning engine (12). The user interface (28) is operable to allow a user to interact with the planning engine (12) in order to adjust the plan (14) and the environment (16) and to select and initiate execution of a selected strategy.
Patent DE-69603580-D1 (DE)
Inventor: LANGFORD COOPER
IPC: B01J21/00
Filed: 1996-03-04
Granted: 1999-09-09
Abstract: A photocatalyst compound comprising: (i) a photocatalyst selected from the group consisting of TiO2, WO3 and mixtures thereof, the photocatalyst being substantially free of sharp, narrow band X-ray reflections at angles corresponding those of crystalline TiO2, WO3 and mixtures thereof, and (ii) a porous, crystalline, adsorbent support material. A process for producing the photocatalyst compound is also disclosed. The process comprises: (i) hydrolysing a non-ionic titanium compound to produce a colloidal suspension having an average particle size of less than about 250  ANGSTROM ; (ii) contacting a porous, crystalline, adsorbent support material with the colloidal suspension to produce an impregnated support; and (iii) calcining the impregnated support to produce the photocatalyst compound. The photocatalyst compound is useful, in the treatment of a fluid containing an organic pollutant.
Patent DE-69614391-D1 (DE)
Inventor: Q-MED AB UPPSALA
IPC: C08B37/08
Filed: 1996-05-28
Granted: 2001-09-13
Abstract: The present invention provides a process for preparing a cross-linked biocompatible polysaccharide gel composition, which comprises: forming an aqueous solution of a water soluble, cross-linkable polysaccharide; initiating a cross-linking of said polysaccharide in the presence of a polyfunctional cross-linking agent therefor; sterically hindering the cross-linking reaction from being terminated before gelation occurs, an activated poly-saccharide being obtained; and reintroducing sterically unhindered conditions for said activated polysaccharide so as to continue the cross-linking thereof to a viscoelastic gel. The invention also provides a gel composition obtainable by such a process as well as gel compositions for different medical uses.
Patent DE-69620825-D1 (DE)
Inventor: ARTER THOMAS C
IPC: C12Q1/26
Filed: 1996-06-21
Granted: 2002-05-29
Abstract: A spectrophotometric assay for the detection of acetaminophen in aqueous fluids is carried out with a dry analytical element. The element comprises a support having thereon one or more reagent layers containing a first enzyme, aryl acylamidase, to cleave the amide bond of acetaminophen to produce p-aminophenol; and a mild oxidizing agent to oxidize the p-aminophenol so that it couples to a water-soluble coupling agent to form a dye that is read at 670 nm. The assay is precise, accurate on serum and plasma samples, and relatively free from significant interferences. The element also allows measurement over a broad dynamic range.
Patent DE-69624342-D1 (DE)
Inventor: MARCOUS P
IPC: G06Q20/10
Filed: 1996-02-12
Granted: 2002-11-21
Abstract: A system and method for fully automated electronic transfer of cash or cash equivalent between a sender and a recipient is shown, including an initiating terminal for receiving a designation of an amount of money to be electronically transferred, an account from which it is to be transferred, and a security code from the sender, a central terminal for storing the amount and the security code in a file in the central terminal, and a dispensing terminal for receiving from the recipient an entry corresponding to the designated amount of money to be transferred and the security code, for providing the entered amount of money and security code to the central terminal for comparison with the information stored in the central terminal's file, and for dispensing to the recipient funds equivalent to the designated amount of money without requiring the recipient to have a card to activate the dispensing terminal.
Patent DE-69637085-D1 (DE)
Inventor: NOVA MICHAEL P
IPC: B01L3/00
Filed: 1996-10-03
Granted: 2007-06-28
Abstract: Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix materials may additionally include fluophors or other luminescent moieties to produce luminescing matrices with memories. The memories include electronic and optical storage media and also include optical memories, such as bar codes and other machine-readable codes. By virtue of this combination, molecules and biological particles, such as phage and viral particles and cells, that are in proximity or in physical contact with the matrix combination can be labeled by programming the memory with identifying information and can be identified by retrieving the stored information. Combinations of matrix materials, memories, and linked molecules and biological materials are also provided. The combinations have a multiplicity of applications, including combinatorial chemistry, isolation and purification of target macromolecules, capture and detection of macromolecules for analytical purposes, selective removal of contaminants, enzymatic catalysis, cell sorting, drug delivery, chemical modification and other uses. Methods for tagging molecules, biological particles and matrix support materials, immunoassays, receptor binding assays, scintillation proximity assays, non-radioactive proximity assays, and other methods are also provided.
Patent DE-69701610-D1 (DE)
Inventor: BAUDIN GILLES M
IPC: B65D47/08
Filed: 1997-07-01
Granted: 2000-05-11
Abstract: A dispensing cap (3) having a body (32) made of a rigid or semirigid material, intended to be mounted on a reservoir (21) containing a product of a fluid-to-viscous consistency, is provided with an opening (4) permitting the dispensing of the product and a lid (5) of a rigid or semirigid material capable of obturating the opening (4). The lid (5) is articulated on the body (32) in the vicinity of an articulation axis (A) so as to be capable of selectively passing from an open position to a closed position, and is connected to the body (32) by a connecting element (10) having one of its ends joined to the lid (5) and its other end joined to the body (32). The connecting element (10) is disposed so as to be situated on one side of the articulation axis (A) in the open position and on the other side of the axis (A) in the closed position. The connecting element (10) is subjected to an elongation when the lid (5) passes from one to the other of its open and closed positions. The connecting element (10) is made of an elastomeric material.
Patent DE-69717044-D1 (DE)
Inventor: DHAINAUT ALAIN
IPC: C07D311/30
Filed: 1997-09-23
Granted: 2002-12-19
Abstract: Flavone derivatives of formula (I), their optical and geometric isomers, mixtures and salts are new. R1 = alkyl; R2 = 3-9C cyclic hydrocarbon (optionally containing at least one intracyclic double bond and optionally substituted), 6-15C polycyclic hydrocarbon (optionally containing at least one double bond and optionally substituted) or 1-13C hydrocarbon (optionally containing one or more double and/or triple bond and optionally substituted); R3 = H or OH; Alk = e.g. 1-6C alkylene; X = O, -CR'= or -CHR'-; R' = H or alkyl; Y = e.g. -C  IDENTICAL  N, -C(=Z2)(R4), C(=Z1)(-O-R4), -C(=Z1)(N(R4)(R4')), N(R4)(R4'), -<+>N(R5)(R5')(R5'') Hal<->, -C(=Z1)(N(R4)(-OR4') or C(=N-R4'')(NR4R4'); Z1 = O or S; Z2 = O, S, =N-OR4 or =N(O)R5; R4, R4', R4" = H, optionally substituted alkyl, aryl, heteroaryl or cycloalkyl; R5, R5' , R5" = optionally substituted alkyl, aryl, heteroaryl or cycloalkyl; provided that: (i) the alkyl and alkoxy groups contain 1-6C and are optionally substituted by halog en and OH, the alkyl groups being optionally further be substituted by alkoxy; (ii) aryl is phenyl or naphthyl (optionally substituted by halogen, alkyl, OH and/or alkoxy; (iii) heteroaryl denotes furyl, thienyl, thiazolyl, isothiazolyl, oxazolyl, pyrrolyl, imidazolyl, pyrazolyl, pyridyl, pyrazinyl, pyrimidyl, pyridazinyl, indolyl, quinolyl, isoquinolyl or quinazolinyl (optionally substituted by one or more halogens, alkyl, OH and/or alkoxy).
Patent DE-69719220-D1 (DE)
Inventor: IMANISHI TAKESHI
IPC: C07H19/10
Filed: 1997-11-18
Granted: 2003-03-27
Abstract: An oligonucleotide analog or an antisense molecule, which is minimally hydrolyzable with an enzyme in vivo, has a high sense strand binding ability, and is easily synthesized, is provided. It is an oligo- or polynucleotide analog containing one or more monomer units being nucleotide analogs of the general formula: <CHEM> where B may be identical or different, and is a pyrimidine or purine nucleic acid base, or a derivative thereof.
Patent DE-69720988-D1 (DE)
Inventor: DUGGER A
IPC: A61K9/00
Filed: 1997-02-21
Granted: 2003-05-22
Abstract: A buccal aerosal spray composition for transmucosal administration of a pharmacologically active compound soluble in a pharmacologically acceptable non-polar solvent comprising in weight percent of the composition: 50 to 95 percent of a pharmaceutically acceptable propellant, 5 to 50 percent of a non-polar solvent, and 0.0025 to 40 percent of the active compound wherein the active compound selected from the group consisting of alkaloids and analgesics.
Patent DE-69723242-D1 (DE)
Inventor: EDWARDS SCOTT
IPC: A61K51/08
Filed: 1997-03-12
Granted: 2003-08-07
Abstract: This invention relates to novel radiopharmaceuticals which are useful as imaging agents for the diagnosis of cardiovascular disorders, infectious disease and cancer, and to kits useful for their preparation. The radiopharmaceuticals of this invention are comprised of a transition metal radionuclide, a transition metal chelator, a biologically active group connected to said chelator, a first ancillary ligand, a second ancillary ligand capable of stabilizing the radiopharmaceutical, optionally having a linking group between said chelator and said biologically active group. Preferred radiopharmaceuticals of this invention have the formula: [(Q)d'Ln-Ch']x-Mt(AL1)y(AL2)z, wherein the shown variables are as defined herein.
Patent DE-69724996-D1 (DE)
Inventor: LAMBERT HANS
IPC: G06F19/00
Filed: 1997-11-06
Granted: 2003-10-23
Abstract: The invention relates to a device and a method for recovering anaesthetic during the use of inhaled anaesthetics. An anaesthetic reflector (5) is used which absorbs anaesthetic medium from the gas exhaled by the patient and desorbs anaesthetic medium to the gas inhaled by the patient. According to the invention a moisture-heat exchanger (12) is arranged in the system which, in an equivalent manner, recovers water vapour from the gas exhaled to the gas inhaled. The moisture-heat exchanger (12) is preferably located between the anaesthetic reflector (5) and the patient (1). The device and the method according to the invention enable the gas inhaled to be moistened to prevent dehydration, as well as increasing the efficiency of the reflector (5).
Patent DE-69725585-D1 (DE)
Inventor: YANAGISAWA HIROAKI
IPC: A61P31/10
Filed: 1997-04-01
Granted: 2003-11-20
Abstract: Phenylalkylcarboxylic acid derivatives of the general formula: <CHEM> wherein R<1> represents an alkyl group and the like, R<2> represents an alkylene group, R<3> represents a hydrogen atom and the like, X represents a substituted or unsubstituted aryl group and the like, Y represents an oxygen atom and the like, Z represents an alkylene group and the like, and W represents an alkyl group and the like), the pharmacologically acceptable salts thereof or the pharmacologically acceptable esters thereof are useful as therapeutic or preventive agents for hyperglycemia and the like.
Patent DE-69727004-D1 (DE)
Inventor: ROLANDO GIOVANNI
IPC: A61F2/82
Filed: 1997-05-06
Granted: 2004-02-05
Abstract: At least some of the segments (2) of the stent (1) are interconnected by first bridge elements (3) extending in the general direction of the longitudinal axis (z) of the stent and having at least one end connected to the concave or inside portion (5) of a respective loop (6) so that, during the radial expansion of the stent, the axial contraction of the segments (2) resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements (3, 4; 30) from the respective concave portions (5). The first bridge elements (3) have opposite ends aligned in the direction of the longitudinal axis (z) of the stent, the two opposite ends being connected to respective concave portions (5) of respective loops of the two segments (2) connected thereby, so that the two segments (2) constitute a section of stent which does not contract substantially longitudinally during radial expansion. Second bridge elements (4') are also provided connecting two adjacent sections of the stent, the second bridge elements (4') connecting convex loop portions. <IMAGE>
Patent DE-69728878-D1 (DE)
Inventor: ELROD L
IPC: C12N15/80
Filed: 1997-06-09
Granted: 2004-06-03
Abstract: The present invention relates to methods of producing hemoproteins comprising (a) introducing into a filamentous fungal cell, which is capable of producing the hemoprotein, (i) one or more first control sequences capable of directing the expression of a heme biosynthetic enzyme encoded by a first nucleic acid sequence endogenous to the filamentous fungal cell, wherein the one or more of the first control sequences are operably linked to the first nucleic acid sequence; and/or (ii) one or more copies of one or more second nucleic acid sequences encoding a heme biosynthetic enzyme; (b) cultivating the filamentous fungal cell in a nutrient medium suitable for production of the hemoprotein and the heme biosynthetic enzymes; and (c) recovering the hemoprotein from the nutrient medium of the filamentous fungal cell.
Patent DE-69733756-D1 (DE)
Inventor: DAVIDSON J
IPC: A61K35/14
Filed: 1997-05-05
Granted: 2005-08-25
Abstract: Compounds of formulae (I) and (II), and their salts, esters and prodrugs, are new: A-B-C-X-Y (I); A-B1-C1-X1-Y (II); A = absent or a nitrogen-protecting group; Y = absent or a carboxy-protecting group; B = absent or 1-197 naturally occurring amino acids (aa) corresponding to residues 334-530 of the 791 aa human plasminogen (hPA) sequence given in the specification; C = Lys-R2-R3-Asp; R2 = Leu or Arg; R3 = Tyr, 3-iodotyrosinyl (ITyr) or Phe; X = absent or is 1-12 naturally occurring aa corresponding to residues 535-546 of hP and its homologues or analogues; B1 = absent or is 1-176 aa corresponding to residues 334-513 of hP; C1 = the 514-523 aa sequence of hP; X1 = absent or is 1-10 aa corresponding to residues 524-533 of hP.
Patent DE-69735292-D1 (DE)
Inventor: JANJIC NEBOJSA
IPC: C07H21/02
Filed: 1997-10-17
Granted: 2006-04-27
Abstract: This invention discloses a method for preparing a complex comprised of a VEGF Nucleic Acid Ligand and a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound by identifying a VEGF Nucleic Acid Ligand by SELEX methodology and associating the VEGF Nucleic Acid Ligand with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further discloses Complexes comprising one or more VEGF Nucleic Acid Ligands in association with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further includes a Lipid construct comprising a VEGF Nucleic Acid Ligand or Complex and methods for making the same.