baber/WOPTO huggingface dataset:
Patent DO-P2009000138-A (DO)
Title: Inhibidores de transcriptasa inversa no nucleósidicos
Inventor: ANTHONY NEVILLE J
IPC: C07D471/04
Filed: 2009-06-12
Abstract: Los compuestos de la fórmula I: son inhibidores de transcriptasa inversa de VIH, en la que Q, R2, R3, R6, T1, T2, y T3 se define en el presente documento. Los compuestos de la formula I, y sus sales y profarmacos farmaceuticamente aceptables, son de utilidad en la inhibicion de transcriptasa inversa de VIH, en la profilaxis y tratamiento de infeccion por VIH y en la profilaxis, retraso del inicio o de la progresion, y tratamiento del SIDA. Los compuestos y sus sales pueden emplearse como ingredientes en composiciones farmaceuticas, opcionalmente combinados con otros antivirales, inmunomoduladores, antibioticos o vacunas. son inhibidores de trasnscriptasa inversa de VIH, en la que Q, R2, R3, R6, T1, T2, T3 se define en el presente documento. Los compuestos de la Fórmula I, y sus sales y profármacos farmacéuticamente aceptables, son de utilidad en la inhibición de transcriptasa inversa de VIH, en la profilasis y tratamiento de infección por VIH y en la profilasis, retraso del inicio o de la progresión, y tratamiento del SIDA. Los compuestos y sus sales pueden emplearse como ingredientes en composiciones farmacéuticas, opcionalmente combinados con otros antivirales, inmonomoduladores, antibióticos o vacunas.
Patent DO-P2021000138-A (DO)
Title: Dispositivos, sistemas y métodos de protección de circuitos modulares configurables para el cumplimiento normativo en ubicaciones peligrosas
Inventor: JOSEPH MICHAEL MANAHAN
IPC: H01H9/04
Filed: 2021-06-25
Abstract: Los dispositivos de protección de circuitos modulares y sistemas de tableros de distribución configurables incluyen características de gestión térmica, operación sin arco, que proporcionan operación segura en ambientes peligrosos a menor costo y sin requerir recintos convencionales a prueba de explosiones y sin que impliquen paquetes conectados en serie proporcionados por separado tales como dispositivos disyuntores y contactores y controles de motor del iniciador.
Patent DO-P2021000238-A (DO)
Title: Conjugados de anticuerpo-fármaco inhibidores de mcl-1 y sus métodos de uso
Inventor: MATTHEW T BURGER
IPC: A61K47/68
Filed: 2021-11-18
Abstract: Se divulgan conjugados de anticuerpo anti-CD74-fármaco. Los conjugados de anticuerpo anti-CD74-fármaco comprenden una unidad de un fármaco inhibidor de Mcl-1 y un anticuerpo anti-CD74 o fragmento de unión al antígeno del mismo que se une a un antígeno blanco, por ejemplo, un antígeno expresado en un tumor u otra célula cancerosa. La divulgación también se relaciona con métodos y composiciones para usar en el tratamiento de cánceres mediante la administración de los conjugados de anticuerpo-fármaco provistos en la presente. Además, se divulgan conjugados de conector-fármaco que comprenden una unidad de un fármaco inhibidor de Mcl-1 y métodos para su elaboración.
Patent EC-SP10010019-A (EC)
Title: Proceso para la producir derivados de piripiropeno e intermediarios para la producción de los mismos
Inventor: GOTO KIMIHIKO
IPC: C07D493/04
Filed: 2010-03-08
Abstract: Se describe un método para producir un compuesto C que está representado por la siguiente fórmula C. C [en la fórmula, R' representa un grupo alquilcarbonilo de C2-6 lineal, ramificado o cíclico.] En el método, como un grupo protector del grupo hidroxi en la posición 7-, R1b se usa [R1b representa un grupo formilo, un grupo alquicarbonilo de C1-4 lineal opcionalmente substituido, un grupo bencilo opcionalmente substituido, un grupo -SiR3R4R5 (en donde R3, R4, y R5 independientemente representan un grupo alquilo de C1-4 lineal o ramificado o un grupo fenilo) que puede estar substituido por un átomo de halógeno, un grupo alquiloxi de C1-4-alquilo de C1-4 que puede estar substituido por un átomo de halógeno, un grupo alquiltio de C1-6-alquilo de C1-6 que puede estar substituido por un átomo de halógeno, un grupo alquilo de C1-4 lineal, ramificado o cíclico que puede estar substituido por un átomo de halógeno (cuando es ramificado ocíclico, es un grupo alquilo de C3-4), un grupo alquenilo de C2-6 que puede estar substituido por un átomo de halógeno, un grupo alquinilo de C2-4 que puede estar substituido por un átomo de halógeno, o un grupo heterocíclico de cinco miembros o seis miembros opcionalmente substituido, saturado o insaturado]. Este método permite producir un derivado de piripiropeno, que tiene un grupo aciloxi en la posición1- y la posición 11- y un grupo hidroxi en la posición 7-, con rendimiento elevado. Este derivado de piripiropeno es útiles como un agente de control de pestes.
Patent EE-200100015-A (EE)
Inventor: BRISTOW ROBERT OWEN
IPC: H04B7/185
Filed: 1999-07-05
Abstract: There is described a radio communications system, including a unit which is able to communicate over a radio communications network such as a satellite or cellular system, and is also able to communicate with a device such as a portable handset over a short range radio link. In order to avoid potentially troublesome interference on the communications path with the communications network, the unit is able to detect the strength of signals received on the short range radio link, and alert the user if those signals are such as to be a potential source of interference.
Patent GB-189701819-A (GB)
Title: Improvements in or relating to the Manufacture of Tracing Linen or Cloth, Leather Cloth, Bookbinders' Cloth, and the like.
Inventor: SACKVILLE JAMES ALLAN
Filed: 1897-01-23
Granted: 1898-01-22
Abstract: 1819. Sackville, J. A., and Swallow, J. H. Jan. 23. Coated fabrics.-Relates to the manufacture of tracing-cloth, leather cloth, bookbinders' cloth, &c. The colour, size, &c. is contained in the trough A, and is convened by the roller B to the ' pad' roller C, which transfers it to the fabric passing round the roller D covered with rubber or the like. The fabric then passes round a large steam-heated roller which dries it so that it can be folded up. After the colour &c. has been applied to the fabric it may be spread by a plate N or a squeegee or a fixed or revolving brush.
Patent GB-189703626-A (GB)
Title: An Improvement in Mechanism connected with Driving Gearing of Carding Engine Flats.
Filed: 1897-02-11
Granted: 1897-12-24
Abstract: 3626. Tyack, R., and Howard & Bullough. Feb. 11. Carding - engines.- Relates to the worm gearing by which the flats are driven. One of the worms E is mounted upon an eccentric bush D, which can be rotated so as to move the worm into or out of gear with its worm-wheel as desired. The bush is locked in the engaging position by a stud.
Patent GB-189707477-A (GB)
Title: Improvements in Cranks for Cycles, Motor Cars, and Engines.
Inventor: DANN AUGUSTUS CARDIGAN FREDRIC
Filed: 1897-03-23
Granted: 1897-11-06
Abstract: 7477. Dann, A. C. F., and Dann, G. T. March 23. Motor road vehicles, power driving-gear for. Relates to variable-throw cranks, shown in connection with a bicycle. The bottom bracket B has fixed to its ends eccentrics A, the straps C of which move on ball bearings. The spindle F carries at one end the chain-wheel G, and at the other a disc H, in both of which are formed diametral guideways I fitted with slide blocks E. The slide blocks also move on ball bearings, and are connected to the eccentric straps by pins D, and have the cranks L keyed on projections K.
Patent GB-189721231-A (GB)
Title: Improvements in Swivel Looms.
Inventor: HOLLINGWORTH EDWARD
Filed: 1897-09-16
Granted: 1898-09-03
Abstract: 21,231. Hollingworth, E., [Hutchins, G. F.]. Sept. 16. Swivel looms.-The swivel shuttles 52 are carried by fingers 49 on a transverse bar 48, and are moved from one finger to the next by levers 54, pivoted to the fingers at 54<1> and operated by a sliding bar 56 on the bar 48. The shuttles are guided by grooves 51, and are held on the fingers by a spring-held ball or pin 57. They may be open at the top to receive the spool or bobbin 53, which may be mounted in a separate holder. The bar 48 is lowered to pass the swivel shuttles into the shed, and the bar 56 is moved horizontally, by means of levers and mechanism under the control of a jacquard. Two cords of the jacquard are connected to opposite arms of an oscillating cam, which engages with studs on an oscillating lever to communicate the motion to the other parts of the mechanism, and is arranged in such a manner as to be locked in its extreme positions. Means are also provided for preventing the lowering of the swivel shuttles while the fly-shuttle mechanism is in operation. By using pivoted fingers which separate the warp threads and push the different sets into the spaces between the fingers, the whole width of the fabric, or any desired width, may be figured by the swivel shuttles.
Patent GB-189726952-A (GB)
Title: Fan Attachment for Rocking Chairs.
Inventor: MASTERSON PATRICK HENRY
Filed: 1897-11-18
Granted: 1898-10-01
Abstract: 26,952. Masterson, P. H., and Bradley, W. J. Nov. 18. Chairs; cradles.-Bell cranks a provided with castors b are pivoted to the rockers d at c. A connecting-rodf is pivoted to the rear lever a at c<1>, and is connected by a pin and slot with the front lever. A connecting-rod h is connected at one end to the bar f by an adjustable sleeve f<1>, and at the other to the tail k of a pivoted toothed sector l, which gears with a pinion on the rod o which carries the fans u. The rod o is in two parts, connected by a sliding sleeve s ; the upper part with the fans may be removed. The fans are pivoted in a double socket t, and are adjusted by links connected to a sliding sleeve v with set-screw v<1>. A spring connected to the bar f and to the lever a keeps the castors in contact with the floor. On rocking the chair the fans are rotated. The invention is applicable to cradles.
Patent GB-189728909-A (GB)
Title: Improvements in Machinery for Discharging Gas Retorts.
Inventor: BRONDER GASTON ALOYSIUS
Filed: 1897-12-07
Granted: 1898-03-19
Abstract: 28,909. Bronder, G. A. Dec. 7. Gas r e t o r t s, discharging. In a machine in which the discharging- rakes are partly supported by a travelling carrier, and partly by a lifting-bar balanced by a counterweighted lever, means are provided for automatically shifting the fulcrum of the said lever as the rake carrier moves forward or backward, so as to compensate for the variation in the weight supported by the lifting-bar ; further, the hydraulic arrangement employed for checking the movement of the rake carrier towards the end of its travel is modified so as to render the check more gradual. Fig. 1 shows a general view of the apparatus. The rake carrier D is propelled backwards or forwards in guides on a carriage A by means of a chain c wound on a drum e driven by rack and pinion gearing operated by a steam engine ; the rake rods h are supported by a lifting-bar E balanced by a counterweighted lever F, and capable of being raised and lowered by an arrangement of levers l<1>, m, l, operated by a handle o. During the motion of the rake carrier the fulcrum p of the counterweighted lever F is shifted in one direction or the other by means of a lever H connected by a rod r to the mechanism which operates the drum e. Fig. 6 shows a section through the hydraulic controller, which consists of a cylinder g fitted with a piston e<6> connected with the operating-mechanism of the chain drum. The two ends of the cylinder are bored out at e<7> and connected together by a passage v opening into the cylinder towards each end, through a series of three ports u, u<1>, u<2>, which are successively closed by the piston for the purpose of gradually arresting the movement of the rake carrier.
Patent GB-189802131-A (GB)
Title: Improvements in Incandescent Gas Lighting Apparatus.
Inventor: SCHODT PAUL GREYSON DE
Filed: 1898-01-26
Granted: 1899-01-07
Abstract: 2131. Schodt, P. G. de. Sept. 17, A.D. 1897, [date claimed under Sec. 103 of Patents &c. Act, A.D. 1883]. Incandescent gas lamps.-Relates to incandescent gas lamps of the kind described in Specification No. 1252, A.D. 1897. Two mixing-chambers A, A' are arranged one above the other, immediately over the gas injector A<3>. The gas from the latter draws in air through the holes a, a, and the mixed gases pass through the conical passage B into the burner C, which has a hemispherical wiregauze cap C<1>. The mantle (not shown) fits over the cap. The lower plate of the gallery has holes D<1>, D<1> in it, covered by two thicknesses of wire gauze. Greater resistance is thus offered to the passage of air through these holes than through the gauze cap, and the escaping products of combustion produce a suction action in the burner. Counter-pressure is also avoided. The chimney may be dispensed with, if desired. In the latter case, a horizontal perforated glass plate F is fitted in place of the chimney and divides the lantern into two parts as shown in Fig. 4. The holes f in the plate having two thicknesses of gauze over them, a suction action is produced as described above.
Patent GB-189804996-A (GB)
Title: Improvements in Luggage Carriers for Velocipedes.
Inventor: WARD MARZY JAMES
Filed: 1898-03-01
Granted: 1898-04-16
Abstract: 4 9 9 6 . Lake, H. H., [Ward, M. J.]. March 1. Luggage-carriers, adapted to be secured to a bicycle handle-bar. A stay 1, bent at 10 to pass the handle-bar stem, has eyes 11 at its ends, to which are becured leashes 2 as shown. Secured to the latter areholding-devices 3 formed by bending wire into the shape shown. Fig. 6 shows the method of securing an article. The leashes 2 are passed once or twice round the handle - bars, through the eyes 11 and round the article 5, its end being drawn tight round the holder 3, when the V-shaped portions 30 grip them and prevent slipping. The leashes 2 may be replaced by straps, in which case buckles replace the holding- devices 3.
Patent GB-189811032-A (GB)
Title: Improvements in Buoys.
Inventor: ANDERSON RICHARD
Filed: 1898-05-14
Granted: 1899-03-11
Abstract: 11,032. Anderson, R. May 14. Buoys.-A bell L, mounted on an elongated vessel or buoy A, is sounded by a hammer K, operated by the current acting on a central paddlewheel C carrying one or more projections or tappets E. The hammer may be attached to a bell-crank lever, or to a sliding rod H fitted with pistons which bear against springs M, P in cylinders N, R. The paddle-wheel shaft works in adjustable hardened centres lubricated by water, and a prow or catcher W prevents the entrance of floating matter into the paddle race.
Patent GB-189811532-A (GB)
Title: A New or Improved Method for the Disposal of Distillers' or Brewers' Refuse.
Inventor: SOUTER GEORGE
Filed: 1898-05-23
Granted: 1899-04-01
Abstract: 11,532. Souter, G., and Souter, J. S. May 23. Drawings to Specification. Waste heat, utilizing.-Relates to the disposal of burnt ale, spent lees, and similar waste liquids from breweries and distilleries so as to avoid the pollution of rivers, and consists in evaporating them in a tubular still heated by steam. The steam for heating the still is generated in a multitubular boiler by the waste heat of the gases from the furnaces which heat the spirit stills in the distillery, and the gases are led along flues beside, beneath, and through the boiler.
Patent GB-189812426-A (GB)
Title: Improvements in Valves.
Inventor: FRANK SALOMON
Filed: 1898-06-02
Granted: 1899-04-08
Abstract: 12,426. Frank, S. June 2. Packing, special methods of.-To prevent leakage, a corrugated tube c is connected at one end to the valve casing or cover, and at the other end to the valve a. Fig. 1 shows the invention applied to a screw-down lift valve, but it may also be applied to self-closing and other valves.
Patent GB-189813659-A (GB)
Title: Toy.
Inventor: HASWELL ROBERT
Filed: 1898-06-20
Granted: 1899-04-22
Abstract: 13,659. H a s - well, R. June 20. Toy parachutes. -A stick A, weighted at B, has secured to it a disc C, of any material, the periphery of which may be connected to the stick by threads D. Feathers &c. may be secured at rightangles to the weighted end of the stick
Patent GB-189813865-A (GB)
Title: Improved Spring Tongs for Forming the Necks of Glass Bottles.
Inventor: SCHREYER LUDWIG
Filed: 1898-06-22
Granted: 1898-08-06
Abstract: 13,865. Schreyer, L. June 22. B o t t l e necks, making.-The spring tongs a<1> are provided with the usual dies h for shaping the exterior of the neck, and, in addition, the core b is provided with movable dies f<1>, f<2>, for shaping the interior. The dies f<1>, f<2> are mounted on arms c<1>, c<2>, pivoted at h', h' to the core b, and, when the tongs are being used, are forced apart by the pins g<2>, g<1> engaging the other ends of the arms h<1>, h<2>. When the operation is complete and the arms a' are released, the dies f<1>, f' are forced together by the action of the spring e, to permit the withdrawal of the core.
Patent GB-189814476-A (GB)
Title: Improvements in Gas Stoves.
Inventor: TITCHETT JOSEPH
Filed: 1898-06-30
Granted: 1899-06-02
Abstract: 14,476. Titchett, J. June 30. Gas cooking-stoves; burners. -The stove is constructed with an oven A which is surrounded by flues through which the heated gases circulate. The combustion chamber B under the oven has a bottom plate C provided with a slot near the front of the stove through which the gas jets from a burner D pass. At the back of the oven is a flue E which opens out into a flue F over the top of the oven. Side flues G, G', G<2>, G<3> and H, H<1>, H<2>, H<3> are formed by means of the ribs g, g<1>, g<2>, g<3> and h, h<1>, h<2>, h<3> which are cast on the external casing K and fit into grooves in the wall of the oven. The products of combustion pass from the chamber B through the flues E, F, and then pursue a zigzag course through the side flues and pass out through an outlet P. The outlet P is fitted with a damper R operated by a rod r. An aperture p in the top of the oven is closed by a damper or shutter p<1>. The passages and flues are enclosed by a casing K formed of two plates k, k<1> with a space between them for non-conducting packing K<1>. A lower chamber A<1> with shelves a<2> may be formed to maintain the heat of, or to heat, articles placed therein. Boiling, grilling, &c. burners D' may be placed over the top plate of the oven and are provided with a suitable frame. The burner D<1>, Fig. 5, is fitted under a plate s<1> provided with apertures. The burner may be moved by a handle d<2>, and in one position the flame is covered by the plate s<1> and deflected downwards for grilling purposes. In the burner D, Fig. 9, a brass or copper tube d is inserted which has perforations increasing in size from the blocked end, thus ensuring an even flame. A gauze strip d<3> is also placed in the tube to cover the perforations and prevent lighting back.
Patent GB-189815980-A (GB)
Title: Improvements in and appertaining to Fire Bars for Furnaces.
Inventor: COTTON ALFRED
Filed: 1898-07-22
Granted: 1899-06-24
Abstract: 15,980. Cotton, A., and Flynt, L. W. G. July 22. Firebars and grates.-The transverse rocker C, which is mounted on trunnions at its ends, has ledges for receiving the depending lugs of the firebars and producing vertical motion, and an upright central portion for producing horizontal movement. The lifting-bar D has no longitudinal movement, whereas the moving bar E partakes of both movements
Patent GB-189816226-A (GB)
Title: Improvements in or relating to Spring Tyres.
Inventor: WALKER THOMAS BARBER
Filed: 1898-07-26
Granted: 1899-02-25
Abstract: 16,226. Walker, T. B. July 26. Tyres, elastic other than pneumatic; felloes or rims. -Relates to spring tyres for cycles, motor cars, and other light road vehicles. The rim consists of a spring rim k, an outer rim a, rods e with enlarged ends in the spring boxes or tubes b, springs f, and an inner rim g. The rim k is covered with a textile fabric or rubber, and carries the solid tyres. The spokes are attached to the inner rim or to the outer rim, or to both rims.
Patent GB-189818049-A (GB)
Title: Improvements in Lubricators.
Inventor: LUTZE ALFRED
Filed: 1898-08-22
Granted: 1898-11-26
Abstract: 18,049. Lutze, A. Aug. 22. Lubricators.-To prevent the rate of flow of oil varying as the head of oil in the reservoir A diminishes, the reservoir is closed and air admitted, through the aperture f, from the central tube C, which communicates with the atmosphere at d. The filling-aperture E is closed by the elastic washer a compressed by the yoke F. The opposite end of the yoke bears on an elastic pad b.
Patent GB-189818557-A (GB)
Title: Improvements relating to Motor-trucks for Electric and other Railways.
Inventor: CAPEWELL GEORGE JOSEPH
Filed: 1898-08-30
Granted: 1899-01-07
Abstract: 18,557. Capewell, G. J. Aug. 30. Electric locomotives and motor vehicles. -Fig. 1 shows a plan, and Fig. 2 a side elevation. The axle-truck has a pair of central traction wheels 1 running upon the single rail 4, each wheel having a motor 6 arranged on each side of it and concentric with its axle 5. A third axle 20 carries small wheels 21 which run between retaining-rails. The truck frame consists of two vertical side plates 7, which are brought together at the ends to reduce atmospheric resistance; and two vertical central plates 9 which form recesses for the traction wheels and are joined together by plates 12 and are connected to the side plates by plates 13. The frame is closed at the top by plates 16, and at the bottom by covers 17 which are hinged at 19. The plates 13 have bottom plates 14 carrying springs 23 for supporting the platform plate 24.
Patent GB-189818870-A (GB)
Title: A Spring Clip for Connecting a Necktie and Collar or other parts of Dress.
Inventor: SQUIRE ALEXANDER JOHN BALMANNO
Filed: 1898-09-03
Granted: 1898-10-08
Abstract: 18,870. Squire, A. J. B. Sept. 3. Necktie retainers; clip fastenings.-Clips for attaching neckties to collars and for other articles of dress are formed of a bent spring A, the arms B of which are curved to form two semi-cylinders, the meeting edges being rounded off at both ends of the arms.
Patent GB-189819618-A (GB)
Title: Improvements in Door or like Locks.
Inventor: HAGLUND JULIUS WALDEMAR
Filed: 1898-09-15
Granted: 1899-07-29
Abstract: 19,618. Haglund, J. W. Sept. 15. Locks, key.-The bolt a and the locking-mechanism are enclosed in a chamber formed by guiding-plates n, m. The bolt tail is thickened at a<1>, and a hole is formed in it to receive a spiral spring b on a guide pin b<1>. Stumps d on each side engage tumblers c pivoted to a pin e passing through a slot in the bolt tail. The key pin l is situated below the plate m, which is cut away at m<o>, Fig. 4, to form wards for the key-bits. The central bit v of the key, Fig. 9, operates the bolt by acting against the vertical face, of the slot k, Fig. 5, while the bits w lift the tumblers. The ward plate at m<2> is made curved or inclined, as shown in Fig. 7, so that the different parts of the bit do not enter the wards simultaneously, and a complete wax impression cannot be taken. The bolt is formed with a projection a<2>, Fig. 5, which limits its outward motion. The tumblers can be lifted from one side of the door &c. by depressing a knob h and the bolt withdrawn bv means of another knob. The lock may be applied to doors, gates, shutters, chests, drawers, safes, &c.
Patent GB-189820868-A (GB)
Title: Improvements in Wind Wheels used for Advertising and Ventilating Purposes.
Inventor: MASON WILLIAM
Filed: 1898-10-04
Granted: 1898-12-23
Abstract: 20,868. Mason, W. Oct. 4. Drawings to Specification. Advertising.-Bicycle or similar wheels, having sails in the form of articles to be advertised, are mounted in ball bearings on a fork, and are caused to revolve by the action of the wind and so display the articles attached to the wheel rim.
Patent GB-189824003-A (GB)
Title: Improvements in Thread Separators for Spinning and like Machines.
Inventor: FELL JOHN CORRY
Filed: 1898-11-14
Granted: 1899-08-26
Abstract: 24,003. Fell, J. C., [HÚlot, C.]. Nov. 14. Ring and traveller frames.-A split ring A, formed by suitably bending a piece of wire, is fi x e d in the ring rail or in a bracket carried by the rail.