baber/WOPTO huggingface dataset:
Patent DE-69333605-D1 (DE)
Inventor: HANDRECK PAUL
IPC: A61K47/12
Filed: 1993-11-18
Granted: 2004-09-30
Abstract: A composition of taxol and polyethoxylated castor oil is pH balanced to have a pH less than 8.1 to improve stability. This composition can include an acid, preferably citric acid, to adjust the pH value. The invention includes a method of formulating a taxol solution for injection by mixing an acid with a carrier material, such as castor oil, to form a carrier solution after which taxol is mixed with the carrier solution to form the taxol solution at a pH of less than 8.1. The method may include the step of slurrying the taxol in alcohol before mixing with the carrier solution.
Patent DE-69413827-D1 (DE)
Inventor: HARLING John
IPC: C07C323/56
Filed: 1994-07-21
Granted: 1998-11-12
Abstract: Compounds of formula (I) and salts thereof are useful for treating accumulation of calcium in brain cells, wherein X represents O, S, NH or a bond; p and q independently represent 0-4 such that the sum of p + q is at least 1; R<1> and R<2> each independently represent hydrogen, C1-6alkyl, C3-6cycloalkyl, or C1-4alkyl-C3-6cycloalkyl; n is 1, 2 or 3; and Ar represents phenyl optionally substituted by 1 to 3 substituents selected from: halo, C1-4alkyl, C1-4alkoxy, C1-2alkylenedioxy, trifluoromethyl, trifluoromethoxy, CN, NO2, amino, mono- or di-alkylamino, optionally substituted benzoyl and Ph(CH2)rY(CH2)s- where Ph is optionally substituted phenyl, Y is oxygen or a bond and r and s each independently represent 0-4 provided that the sum of r + s is not greater than 4, or Ar represents an optionally substituted unsaturated monocyclic heteroaryl ring system containing 5 or 6 ring members, or an optionally substituted, unsaturated or partially saturated bicyclic aryl or heteroaryl ring system containing 8-10 ring members.
Patent DE-69415659-D1 (DE)
Inventor: ANTRIM RICHARD L
IPC: C12N15/75
Filed: 1994-02-10
Granted: 1999-02-11
Abstract: A mutant alpha-amylase is provided that is the expression product of a mutated DNA sequence encoding an alpha-amylase, the mutated DNA being derived from a precursor alpha-amylase, which is a Bacillus alpha-amylase, by substitution or deletion of an amino and at a position equivalent to M + 15 in B licheniformis alpha-amylase. The mutant alpha-amylase are suitable for use in detergent compositions and in process for starch liquification.
Patent DE-69423680-D1 (DE)
Inventor: COOSEMANS PIERRE
IPC: C08L23/10
Filed: 1994-08-11
Granted: 2000-05-04
Abstract: Disclosed is a multilayered cast film which comprises:   A) at least one layer of a crystalline homopolymer of a C3-C6  alpha -olefin, or a random copolymer of propylene with ethylene and/or a C4-C10  alpha -olefin, or a composition of crystalline random copolymers of propylene with ethylene and/or a C4-C8  alpha -olefin (Component A); and B) at least one layer of a propylene homopolymer, or a propylene copolymer with ethylene or a C4-C10  alpha -olefin, or a propylene copolymer with ethylene and a C4-C10  alpha -olefin, having an elongation at break lower than 30% (Component B); said film having an elongation at break greater than 100%.
Patent DE-69426727-D1 (DE)
Inventor: MITRA SEKHAR
IPC: A61K9/00
Filed: 1994-12-21
Granted: 2001-03-29
Abstract: The present invention relates to improved topical pharmaceutical compositions in the form of a wipe or towelette having improved aesthetics which are useful for imparting antimicrobial actives. In particular, it relates to topical moisturizing wipe compositions containing one or more antimicrobial active compounds. These compositions are also useful for providing relief from symptoms associated with, for example, vaginal yeast infections.
Patent DE-69431562-D1 (DE)
Inventor: KNEPP VICTORIA M
IPC: A61K38/22
Filed: 1994-08-16
Granted: 2002-11-21
Abstract: Aqueous formulations of nerve growth factor suitable for lyophilization and subsequent reconstitution in which nerve growth factor is admixed with sugars and buffer are provided.
Patent DE-69431979-D1 (DE)
Inventor: IGARASHI TATSUYA
IPC: G11B7/00
Filed: 1994-06-14
Granted: 2003-02-13
Abstract: This invention relates to a recording medium management method, and digital data for computer processing are stored on a magnetooptic disk that is usually used to record compressed digital audio data. When computer data are recorded to clusters (16-27) of a data recording area, the range of the clusters (16-27) is secured as a usable range in a management table (parts table) of U-TOC. On the parts table (02h), a segment using is recorded using the cluster (16) as a start address and the cluster (27) as an end address. To manage the recording state of the computer data, FAT (File Allocation Table) is separately prepared to manage the recording state of the clusters (16-27). <IMAGE>
Patent DE-69434622-D1 (DE)
Inventor: BLAECKBERG LARS
IPC: C12N15/85
Filed: 1994-02-25
Granted: 2006-04-20
Abstract: The invention discloses nucleic acids encoding variant Bile Salt Stimulated Lipase (BSSL; EC 3.1.1.1). The encoded variant BSSL enzymes maintain catalytic activity but contain fewer glycosylation sites that full-length BSSL. This reduced glycosylation facilitates purification and characterization of recombinant BSSL proteins.
Patent DE-69503245-D1 (DE)
Inventor: REILAND MARY
IPC: B62B7/00
Filed: 1995-05-24
Granted: 1998-08-06
Abstract: A child carriers accessory attachable to a shopping or luggage cart which does not significantly reduce the functionality of the cart.
Patent DE-69509690-D1 (DE)
Inventor: MUHA KRUNOSLAV
IPC: C08G18/18
Filed: 1995-03-15
Granted: 1999-06-24
Abstract: A method for preparing a polyester flexible slabstock polyurethane foam which comprises reacting an organic polyisocyanate and a polyester polyol in the presence of a blowing agent, optionally a cell stabilizer and a catalyst composition consisting essentially of N-methylimidazole or 1,2-dimethylimidazole, or both.
Patent DE-69513285-D1 (DE)
Inventor: BENSON BRADLEY
IPC: A61P29/00
Filed: 1995-06-21
Granted: 1999-12-16
Abstract: Novel hydroxyalkylammonium-pyrimidine of the formula   <IMAGE>   and nucleoside derivatives have been found to be useful as inhibitors of inflammatory cytokines. They can be used, inter alia, in the therapy of septic shock, cachexia, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and AIDS. The compounds are typically prepared by reaction of an iodo substituted nucleoside with the appropriately substituted hydroxyalkylamine.
Patent DE-69516033-D1 (DE)
Inventor: VAN GEEL JACOBUS A P
IPC: B21D13/04
Filed: 1995-05-04
Granted: 2000-05-11
Abstract: A method for stiffening plate-like material for a spatial structural member, for example a cable trough, which stiffening takes place by locally pressing through the material to form ridges, wherein at least on one side of the ridge the thickness of the material is made smaller, whereby the material is extended, this such that internal tensions resulting from cold deformations in the plate are eliminated. <IMAGE>
Patent DE-69531934-D1 (DE)
Inventor: RUDNIC EDWARD M
IPC: A61K38/23
Filed: 1995-03-15
Granted: 2003-11-20
Abstract: A pharmaceutical preparation including a drug incorporated into hydrophobic particles comprised of long chain carboxylic acid or ester thereof or long chain alcohol, wherein the particles are incorporated into a unit dosage form and are individually coated with an enteric coating and/or the unit dosage form includes an enteric protective material.
Patent DE-69534948-D1 (DE)
Inventor: KOHN DONALD B
IPC: C12N15/85
Filed: 1995-12-19
Granted: 2006-05-24
Abstract: Retroviral plasmid vectors which include an enhancer region obtained from a virus selected from the group consisting of Myeloproliferative Sarcoma Virus and polyoma virus, and a primer binding site obtained from murine retrovirus. The retroviral plasmid vector does not include a negative control region. The vector also may include a nucleic acid sequence which encodes demethylation of cytosine residues in the proviral LTR. Such plasmid vectors are especially useful in the generation of retroviral vector particles which may be expressed in embryonic cells, such as embryonic stem cells.
Patent DE-69627320-D1 (DE)
Inventor: HERBERT F
IPC: A61K48/00
Filed: 1996-05-15
Granted: 2003-05-15
Abstract: The present invention relates to a method for forming microparticles of a material from microdroplets of a solution, wherein the solution comprises the material dissolved in a solvent. The method includes the steps of directing the microdroplets into a freezing zone, wherein the freezing zone is surrounded by a liquified gas, and wherein the microdroplets freeze. The frozen microdroplets are then mixed with a liquid non-solvent, whereby the solvent is extracted into the non-solvent, thereby forming the microparticles.
Patent DE-69633278-D1 (DE)
Inventor: HUMES DAVID
IPC: A61K9/48
Filed: 1996-06-04
Granted: 2004-10-07
Abstract: Disclosed is an implantable device for delivering a pre-selected molecule, for example, a hormone, into a mammal's systemic circulation. The device comprises a blood permeable element that can be anchored to an inner wall of an intact blood vessel. The device also comprises a capsule that is held in place within the blood vessel by the anchored blood permeable element. The capsule encloses viable cells which produce and secrete the pre-selected molecule into blood passing the capsule. The invention also provides a minimally invasive method for percutaneously introducing into a pre-selected blood vessel the device of the invention.
Patent DE-69634424-D1 (DE)
Inventor: SMITH M
IPC: B01J31/14
Filed: 1996-12-18
Granted: 2005-04-07
Abstract: The present invention relates to a process which comprises the non-hydrolytic transformation of an aluminoxane precursor composition, comprising carbon-to-oxygen bonds which can be alkylated by an alkylaluminum moiety, into a catalytically useful aluminoxane composition. In one embodiment of this invention, the catalytically useful aluminoxane composition is a polymethylaluminoxane composition substantially free of trimethylaluminum. The intermediate precursor is formed by the reaction of a trialkylaluminum compound, or a mixture of trialkylaluminum compounds, and a compound containing a carbon-to-oxygen bond, such as an alcohol, ketone, carboxylic acid, or carbon dioxide. Either unsupported or supported polymethyl-aluminoxane compositions can be formed.
Patent DE-69708484-D1 (DE)
Inventor: NISHINO CHIKAO
IPC: C07D213/40
Filed: 1997-03-18
Granted: 2002-01-10
Abstract: A pyridine derivative or a salt thereof expressed by the following formula 1: <CHEM> wherein W represents a group expressed by the following formula 2 or formula 3; <CHEM>   <CHEM>  wherein     R1 represents an alkenyloxy group;   n represents 1 or 2;   Ra represents a lower alkyl group; and   Rb represents a halogen atom; and wherein each of R2 and R3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group;   Y represents a group expressed by - S-, -NH- or - CONH-;   m represents an integer of 0 to 2; and   p represents 0 or 1.   The pyridine derivative has an anti- ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.
Patent DE-69710906-D1 (DE)
Inventor: MOULIN JEAN-MICHEL
IPC: E02D5/14
Filed: 1997-09-24
Granted: 2002-04-11
Abstract: A method of sealing sheet pile joints using a paraffinic product to seal the gripping elements of the sheet piles. The paraffinic products usable for sealing the gripping elements of sheet piles have a drop point lying between 100 and 140° C. and a cone penetration of between 20 and 50 mm/10. In a preferred embodiment, the paraffinic product contains at least 50% paraffin waxes, and may also incorporate mineral oils, bonding agents, antioxidants and/or other normal additives. According to another embodiment, the paraffinic products usable for sealing the gripping elements of sheet piles have a resistance to hydrostatic pressure of at least 0.12 bar/mm, preferably at least 0.22 bar/mm.
Patent DE-69712392-D1 (DE)
Inventor: PETERI HENRI BERNARD
IPC: E03C1/042
Filed: 1997-02-28
Granted: 2002-06-13
Abstract: A water tap for the purpose of dispensing hot water intended for arrangement on a horizontal face (3), comprising a shut-off cock (8) which is connectable, by an inlet (8a) thereof, to a hot-water source and connected, by an outlet thereof and via a water supply (12), to a pivotable discharge (2), of which discharge in inlet side comprises a straight length of tubing (5), the straight length of tubing (5) being clampingly arranged in a guide (1a,1b,16) of a tube guide housing (1) so that the discharge (2) is adjustable in the direction of the longitudinal center line of the straight length of tubing (5) and retains this position in any adjusting position under the influence of the clamping guide (1a,1b,16). The water supply (12) comprises a flexible hose (12) being sufficiently flexible to keep forming a loop without buckling during adjustment of the discharge (2), but still sufficiently rigid to undergo only a slight degree of torsion during rotation of the discharge (2). Heat-insulating material (14,15) is provided in the discharge (2) and the tube guide housing (1). <IMAGE>
Patent DE-69714591-D1 (DE)
Inventor: VIELKIND JUERGEN R
IPC: A61K38/00
Filed: 1997-05-28
Granted: 2002-09-12
Abstract: Methods and compositions are provided for detecting antigens having a specific epitope associated with melanoma and prostatic carcinoma. The epitope is present in melanoma cells and prostatic cancer cells but is essentially absent from melanocytes and normal prostatic tissue. The antibody can be used in diagnostic methods for histochemical detection of human melanoma and prostate carcinoma, of various progression stages and in treatment of melanoma and prostate carcinoma.
Patent DE-69718822-D1 (DE)
Inventor: MARKERSEN OLE
IPC: E05F15/619
Filed: 1997-11-25
Granted: 2003-03-06
Abstract: The openable window sash is in the closed position secured to the frame by locking means on the sash engaging lock fittings on the frame. After release of the locking means from the lock fittings my means of an operating device the sash is moved to an open position by at least one window operator (14, 15) positioned at a frame member. The sash is moved to a ventilating position by the operating device which has a motor (3) which via a driving member (4) moves a locking rod (7) which is longitudinally displaceable in a sash member (2), said locking rod being also in engagement with a relative to the longitudinal frame member inclined section (10) of a track (9) in the lock fitting (8) of the frame. By longitudinal displacement of the locking rod the sash is moved in a direction away from the frame, the sash being, until the ventilating position has been reached, secured to the frame by the engagement between the locking rod and the track of the lock fitting.
Patent DE-69720785-D1 (DE)
Inventor: TUMILTY ANTHONY
IPC: B01J23/52
Filed: 1997-01-22
Granted: 2003-05-15
Abstract: The invention provides a method of reducing nitrogen oxide which includes the steps of contacting the nitrogen oxide with a catalyst which comprises an oxide support having captured thereon gold and a transition metal, the gold being complexed with the transition metal. The catalyst is preferably a catalyst as described in either WO 94/19092 or WO 96/14153.
Patent DE-69728890-D1 (DE)
Inventor: BROWN W
IPC: F04F5/46
Filed: 1997-09-23
Granted: 2004-06-03
Abstract: An improved fuel transfer pump is provided for relatively high flow transfer of fuel from one aircraft to another during an inflight refueling procedure, wherein the fuel transfer pump includes a jet-type scavenge pump for evacuating residual fuel from a fuel line or manifold. The scavenge pump comprises a venturi element connected along a recirculation conduit through which a small fuel flow is diverted from the high pressure discharge side of the fuel transfer pump for return to the fuel tank. The recirculation fuel flow induces a vacuum in a suction throat of the venturi element, and this vacuum is coupled by a suction line to evacuate residual fuel from the fuel line or manifold to the fuel tank. A flow baffle is mounted along the recirculation conduit downstream from the venturi element to ensure flooding and priming of the scavenge pump.
Patent DE-69729946-D1 (DE)
Inventor: SEIBERT KAREN
IPC: C07D231/12
Filed: 1997-10-14
Granted: 2004-08-26
Abstract: The present invention relates to a pharmaceutical composition for the treatment of a neoplasia, which comprises a compound of formula II and an anti-neoplastic agent
Patent DE-69737834-D1 (DE)
Inventor: CADE DOMINIQUE
IPC: A61K9/36
Filed: 1997-12-05
Granted: 2007-08-02
Abstract: The present invention relates to non-animal polymer compositions suitable for film forming, particularly hard and soft capsules, comprising water soluble cellulose ethers, hydrocolloides and sequestering agents.
Patent DE-69800712-D1 (DE)
Inventor: BOURNE CARL
IPC: B60L50/15
Filed: 1998-01-12
Granted: 2001-05-23
Abstract: A parallel hybrid vehicle (10) includes an electric motor (24) and an internal combustion engine (23) which is connected to a manual gearbox via a clutch (22). A sensor (30) monitors for disengagement of the clutch (22) during a gear change and a control unit (26) controls the motor (24) so as to compensate for the reduction in torque from the engine during gear change. This helps the driver to keep proper control of the vehicle during gear change, particularly on steep slopes.
Patent DE-69808754-D1 (DE)
Inventor: SHERMAN EDWARD
IPC: B41J2/02
Filed: 1998-04-29
Granted: 2002-11-21
Abstract: A droplet generator for a continuous stream ink jet print head has a cavity for containing ink, and nozzle orifices passing ink from the cavity to form jets. An actuator means vibrates the ink in the cavity such that each jet breaks up into ink droplets. The actuator means is disposed on the opposite side of the cavity to the nozzle orifices, and a surrounding wall of the cavity extends between the actuator means and nozzle orifices for containing the ink therebetween. The surrounding wall has inner and outer constituent wall. The resistive component of the wave impedance of the outer wall passively damps vibration of the inner wall by dissipating its vibration; the reactive component of the wave impedance of the outer wall actively restrains vibration of the inner wall, ensuring that each jet breaks up into ink droplets at the same predetermined distance from its respective nozzle orifice.
Patent DE-69810155-D1 (DE)
Inventor: GUIDETTI ANTONIO
IPC: C04B41/49
Filed: 1998-03-17
Granted: 2003-01-23
Abstract: A process for the production of fibre-reinforced cement sheets which allows the thermo-hygrometric resistance thereof to be improved without adversely affecting the strength is described.
Patent DE-69813619-D1 (DE)
Inventor: BLUMENSTEIN-STAHL ANNEMARIE
IPC: A23L27/30
Filed: 1998-12-01
Granted: 2003-05-22
Abstract: The present invention relates to substantially alcohol free beverages having a sweetener system which ensures the full perception of the flavour system within the beverage while at the same time comprising flavanols as a sweetness cutting material which reduces the sweetness impression of the sweetener system. In particular the present invention relates to beverages which are considered most appealing to an adult taste, having a full flavour impression while being considered less sweet than conventional beverages usually designed for children, who prefer a stronger sweetness impression.
Patent DE-69828977-D1 (DE)
Inventor: SCHMITT J
IPC: A61F2/06
Filed: 1998-09-03
Granted: 2005-03-17
Abstract: An implantable textile prosthesis includes a first woven section having a tubular branch wall defining a fluid passageway therethrough. The tubular branch wall includes an elongate tubular extent and an asymptotically flared tubular extent, which is asymptotic with respect to the tubular branch wall. The asymptotically flared tubular extent includes a weaving pattern having a plurality of warp yarns and fill yarns and incorporating a gradual change in the number of warp yarns with respect to the fill yarns to provide a seamless and substantially fluid-tight transition region along said flared tubular extent. The tubular branch wall may be sutured to an elongate tubular main wall to provide an implantable tubular textile prosthesis particularly useful in branched end-to-side anastomoses. The tubular main wall may be heat-settably arched to resemble the natural arch of the aorta.
Patent DE-69837274-D1 (DE)
Inventor: SARAVOLAC EDWARD G
IPC: A61K48/00
Filed: 1998-10-09
Granted: 2007-04-19
Abstract: The present invention relates to lipid-based formulations for nucleic acid delivery to cells, methods for the preparation of such formulations and, in particular, to lipid encapsulated plasmids. The compositions are safe and practical for clinical use. In addition, the present invention provides methods for introducing nucleic acids into cells and for inhibiting tumor growth in cells using such lipid-nucleic acid formulations.
Patent DE-69902853-D1 (DE)
Inventor: LE BOULCH MARIANNE
IPC: F27D11/00
Filed: 1999-06-14
Granted: 2002-10-17
Abstract: A resistance heater has a ceramic resistance heating portion (12) comprising a sintered mixture of silicon carbide particles, electrically conductive phase forming dopant particles and mineral particles. Preferred Features: The dopant particles consist of nickel oxide and the mineral particles consist of alumina and yttrium oxide.
Patent DE-69908694-D1 (DE)
Inventor: KNIGHT DAVID JOHN
IPC: B60K17/00
Filed: 1999-04-07
Granted: 2003-07-17
Abstract: A material-handling vehicle (10) comprising a structure (11) having, ground engageable propulsion means (33,34), a loader arm (60) mounted for up and down swinging movement, an operator's cab (50), an engine (71) having an output to provide power for said movement of the loader arm (60) and propulsion of the vehicle (10) and drive to connect the output to the ground engageable propulsion means (33,34) to propel the vehicle (10), wherein the output of the engine (71) is kinematically connected to a change speed gearbox (72) which drives at least a rear axle (31) of the vehicle (10), at least one of the engine (71) and change speed gearbox (72) being connected to the rear axle (31) to provide a sub-assembly (A) and said sub-assembly (71) being mounted on said structure (11) for pivotal movement about an axis which lies in, or is parallel to, a plane which contains the longitudinal axis (X-X) of the vehicle (10). <IMAGE>
Patent DE-69913442-D1 (DE)
Inventor: GREUCEAN DRONCUTA PAVELUT
IPC: B05B1/34
Filed: 1999-07-12
Granted: 2004-01-22
Abstract: The nozzle comprises a head with an inlet and one or more outlets, each containing a diffuser (4) in the form of a bush (5) with a conical inner cavity containing a conical component (6), and an outlet (8). The conical component has three spiral grooves (14a, 14b, 14c) with their ends at the base of the cone connecting with the interior of the diffuser via separate orifices (15a) at an angle of 120 degrees to one another, and at the tip of the cone meeting a common outlet (8). The inner surface of the bush and outer surface of the cone have matching threads for screwing together.