baber/WOPTO huggingface dataset:
Patent CA-2755088-A1 (CA)
Inventor: Travis Todd
IPC: E21B33/03
Filed: 2011-10-11
Abstract: A rotating breech lock rotates tubing to distribute wear caused by a rotating or reciprocating rod of an artificial lift system. The rotating breech lock has a spool that disposes on a wellhead. A bowl element disposes in the spool's bore, and a hanger fits into the spool and lands on the bowl element with a thrust bearing.  Above the hanger, a load ring fits against the hanger with a bearing, and a hold-down sleeve and locking pins hold the load ring against the hanger. The spool has a worm that mates with a wheel defined about the hanger so turning the worm by a ratchet or other mechanism rotates the hanger. Internally, the hanger has a bore with opposing shoulders separated by gaps. A mandrel couples to the tubing and disposes up into the hanger. Protrusions or keys on the hanger can selectively align with the gaps and the shoulders depending on how the mandrel is rotated in the hanger bore.
Patent CA-2756578-A1 (CA)
Title: Drug delivery device
Inventor: HARMS MICHAEL
IPC: A61M5/315
Filed: 2010-03-31
Abstract: A mechanism (11, 12, 14) in the body (4) is used to drive a piston rod (8) and comprises means (14, 17, 25) for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means (15) are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element (13) inhibiting a reversal of the movement of the piston rod when being reset.
Patent CA-2758267-A1 (CA)
Inventor: WANG YEQING
IPC: G11B27/10
Filed: 2010-04-13
Abstract: A method and apparatus is provided for recording a program. The method includes storing, in response to a use request, at least one content file that includes first and second program segments that are spliced to form a single program. At least one index file is created and stored. The file index includes program specific information associated with the first and second program segments. The index file also includes an identification of a splice point denoting a transition between the first and second program segments. In addition, a splice index is created and stored. The splice index includes timing information specifying a time at which the splice point occurs.
Patent CA-2760721-A1 (CA)
Title: Process for preparing carbodiimides
Inventor: BLAUL ANKE
IPC: C08G18/02
Filed: 2010-05-03
Abstract: A method for producing compounds comprising at least one carbodiimide group is described, by reacting at least one isocyanate-containing starting compound or a derivative thereof, wherein the method is conducted in at least two stages.
Patent CA-2761677-A1 (CA)
Title: Devices, methods and kits for forming tracts in tissue
Inventor: DREWS MICHAEL
IPC: A61B17/12
Filed: 2010-05-14
Abstract: Described here are devices, methods, and kits for forming one or more tracts in tissue. The tracts may be formed in any suitable or desirable tissue, and may seal relatively quickly without the need for a supplemental closure device. In some variations, the methods may comprise advancing a tissue-piercing member along a predetermined path of a tract- forming device to form one or more tracts in tissue (e.g., a vessel wall). The tract or tracts may, for example, provide access for one or more tools.
Patent CA-2764545-A1 (CA)
Inventor: DE STROOPER BART
IPC: C07K16/40
Filed: 2010-06-15
Abstract: The present invention relates to antibodies with a specificity for BACE1. More specifically, the invention provides monoclonal antibodies which bind to BACE1 and are capable of inhibiting the activity of BACE1 and methods producing these antibodies. Said antibodies can be used for research and medical applications.  Specific applications include the use of BACE1 specific antibodies for the treatment of Alzheimer's disease.
Patent CA-2764934-A1 (CA)
Title: Characterization of re-useable chromatography equipment
Inventor: BELOUSOV ANTON
IPC: G01N30/86
Filed: 2010-06-22
Abstract: Herein is reported a method for determining whether a re-useable chromatography column packing, which is used at least for the second time in a purification step of a purification of a polypeptide, has reduced separation efficacy in said purification step of said purification of said polypeptide. The method comprises the following steps: a) identifying and determining the experimental data of an inert change of at least one physicochemical parameter of a mobile phase passing through said re-useable chromatography column packing, b) determining the parameters of a function of formula I by fitting the experimental data of the inert change of the physicochemical parameter of the at least second use, c) determining the difference between the experimental data of the inert change of the physicochemical parameter of the at least second use and the function of formula I with the parameters determined in step b), d) calculating the difference between the maximum value and the minimum value of the difference determined in step c) and normalizing said difference, e) determining reduced separation efficacy of said re-useable chromatography column packing when the absolute value of the difference calculated in step d) is more than 0.1, wherein the function of formula I is with the amplitude P1, the starting value AO, the mean value m, the standard deviation s, and wherein er.function. is the error function.
Patent CA-2765772-A1 (CA)
Title: Biomarkers and methods for determining efficacy of anti-egfr antibodies in cancer therapy
Inventor: STROH CHRISTOPHER
IPC: C12Q1/68
Filed: 2010-06-15
Abstract: The invention relates to biomarkers based on gene expression products and methods for determining the efficacy of anti-EGFR antibodies in the treatment of EGFR expressing cancer. The invention is further related to the prediction of sensitivity or resistance of a patient suffering from EGFR expressing cancer to the treatment of said patient with a specific anti- EGFR antibody. The invention is preferably related to the identification of respective biomarkers that allow a better prediction of the clinical outcome of the treatment with anti- EGFR antibodies in patients with KRAS wild-type tumors. In this context, the invention especially relates to anti-EFGR antibody c225/cetuximab (Erbitux®) and its use in patients suffering from colorectal Cancer (CRC).
Patent CA-2765831-A1 (CA)
Inventor: HONIBALL JOHN ROBERT
IPC: A61B17/17
Filed: 2010-06-24
Abstract: A bone cutting guide system (110) includes a bone cutting guide assembly (111) and a positioning guide (114). The bone cutting guide assembly (111) includes a base pin (112) and a guide mounting arrangement comprising a placement pin guide (113). The pin (112) has an elongate cylindrical shaft (115) having a penetrating end (117). The positioning guide (114) includes a moulding (116) and a hollow cylindrical guide post (118) fixed to the moulding (116). The moulding (116) is constructed from anatomical data obtained by means of a radiographic scan of the head (55) of the femur (14) prior to surgery. The placement pin guide (113) has a handle (121) and a hollow cylindrical guide sleeve (119) dimensioned to slidingly receive the guide pin (112) therein. In use, the moulding (116) is fitted to the head (55) of the femur. The guiding formation (119) of the pin placement guide (113) is received in the post (118) for guiding the insertion of the pin (112) into the head (55) of the femur (14).
Patent CA-2767121-A1 (CA)
Inventor: HUNTER MARK
IPC: A61F2/68
Filed: 2010-06-28
Abstract: A known prosthesis comprising parts which are movable relative to one another, by way of an actuator and a control, offers more than one kind of movement, positioning the movable parts in a known reference position, such as a fully open position, before applying appropriate power to the movable parts to effect a further movement, which may result in energy being wasted whilst it is first moved into the reference configuration. Changes in frictional forces over time may result in error. Accordingly, the present invention is directed to a prosthesis in which a movement transducer is connected to a control and also to an actuator to provide signals to the control indicative of the amount of movement between two parts of the prosthesis effected by the actuator, and the control operates the actuator in dependence upon the signals it receives from the transducer.
Patent CA-2767247-A1 (CA)
Inventor: HUANG JIAN
IPC: F02P21/00
Filed: 2012-02-07
Abstract: An apparatus and method for igniting a gaseous fuel directly introduced into a combustion chamber of an internal combustion engine comprises steps of heating a space near a fuel injector nozzle; introducing a pilot amount of the gaseous fuel in the combustion chamber during a first stage injection event; controlling residency of the pilot amount in the space such that a temperature of the pilot amount increases to an auto-ignition temperature of the gaseous fuel whereby ignition occurs; introducing a main amount of the gaseous fuel during a second stage injection event after the first stage injection event; and using heat from combustion of the pilot amount to ignite the main amount.
Patent CA-2769241-A1 (CA)
Title: Dose counter for a metered-dose inhaler
Inventor: KAAR SIMON G
IPC: A61M15/00
Filed: 2010-07-28
Abstract: Disclosed herein is a dose counter (118) for counting doses of medicament dispensed by or remaining in a metered-dose inhaler. The dose counter comprises: a rotatably mounted gear wheel (130) having a circular arrangement of ratchet teeth (132); a display coupled to the gear wheel, the display having a visible array of dose counting indicia indexable in response to rotary motion of the gear wheel; and an actuator mechanism having a driver (152) for rotatably driving the gear wheel in response to the dispensation of a medicament dose, the driver being arranged to engage the ratchet teeth of the gear wheel. The actuator mechanism comprises a pivotally mounted lever or linkage having an input portion. The lever or linkage is arranged to amplify a linear stroke at the input portion such that a linear stroke of the driver exceeds the linear input stroke. By amplifying the stroke in this way, the risk of undercounting due to insufficient stroke length may, be reduced.
Patent CA-2769384-A1 (CA)
Title: Linked area parameter adjustment for spinal cord stimulation and associated systems and methods
Inventor: WALKER ANDRE B
IPC: A61N1/34
Filed: 2010-07-28
Abstract: Systems and methods for managing pain in a patient using an electrical waveform that link the modulation of a waveform parameter for different areas of a patient. One embodiment in a system for managing pain in a patient comprises an electric device configured to be implanted into the patient and including a plurality of electrodes having at least a first electrode associated with a first area of the patient and a second electrode associated with a second area of the patient. The system further includes an implantable device configured to be coupled to the electrode device and having a computer-operable medium programmed to change the waveform parameter applied to the first electrode and automatically set the waveform parameter applied to the second electrode based on a relationship between a first therapy range and a second therapy range of the waveform parameter.
Patent CA-2770844-A1 (CA)
Inventor: RUSSO JOSEPH MICHAEL
IPC: C10L10/08
Filed: 2010-08-16
Abstract: A composition is provided that contains a major amount of a base oil and a minor amount of at least one butylene oxide-modified alkyl-bis-ethoxylated monoamine, wherein the alkyl group have carbon atoms in the range of 8 to 22 and ethylene oxide to butylenes oxide is in a ratio in the range of 3:1 to 2:1. The composition provides improved friction modification in fuel and in lubricating oils.
Patent CA-2771561-A1 (CA)
Inventor: BRANDO DANNY
IPC: G06F7/04
Filed: 2009-09-30
Abstract: A system and method for performing a security check may include using at least one processor to periodically check a status of a flag, generate and store a baseline representation of modules stored on the device where the flag is determined to be set to a first state, and, where the flag is determined to be set to a second state, generate an active representation of modules stored on the first device, compare the active representation of modules to the baseline representation of modules, and, responsive to a determination in the comparing step of a difference between the baseline and active representations of modules, output an alert. The flag status may depend on an association of the device with one of a plurality of authorization policies, each mapped to one of the two states. Results of the comparison may be appended to an activity log of the device.
Patent CA-2772138-A1 (CA)
Title: Device for ophthalmic laser surgery
Inventor: DONITZKY CHRISTOF
IPC: A61F9/01
Filed: 2009-12-07
Abstract: The present invention relates to a device 10 for ophthalmic laser surgery, with an optical imaging system for imaging a treatment laser beam 14 onto a focal point, with a temperature-measuring means for the measurement of a temperature assigned to the imaging system, and with an electronic control arrangement (22) connected to the temperature-measuring means and designed to control the focal point adjustnment as a function of the measured temperature. Moreover, the present invention also relates to an associated method.
Patent CA-2772199-A1 (CA)
Title: B7-h4 fusion proteins and methods of use thereof
Inventor: LANGERMANN SOLOMON
IPC: G01N33/68
Filed: 2010-08-31
Abstract: Fusion proteins containing B7-H4 polypeptides are disclosed. The B7-H4 fusion proteins can include full-length B7-H4 polypeptides, or can contain a fragment of a full-length B7-H4 polypeptide, including some or all of the extracellular domain of the B7-H4 polypeptide. Methods for using the fusion proteins to downregulate T cell activation and for the treatment of inflammatory and autoimmune diseases and disorders are also disclosed. The B7-H4 fusion proteins are useful for treating inflammation by inhibiting or reducing differentiation, proliferation, activity, and/or cytokine production and/or secretion by ThI, ThI 7, Th22, and/or other cells that secrete, or cause other cells to secrete, inflammatory molecules, including, but not limited to, IL-lß, TNF-a, TGF-beta, IFN-?, IL-17, IL-6, IL-23, IL-22, IL-21, and MMPs; or enhancing IL-IO secretion by Tregs, increasing the differentiation of Tregs, increasing the number of Tregs, or combinations thereof.
Patent CA-2774799-A1 (CA)
Title: Process for production of chlorine dioxide
Inventor: DAHL ANDERS
IPC: C01B11/02
Filed: 2010-10-07
Abstract: The present invention relates to aprocess for productionof chlorine dioxide comprising: reacting in an acidic reaction mediumin a reaction vessel an alkali metal chlorate or chloric acid and methanol to generate chlorine dioxide,withdrawingfrom the reaction vessel a gas comprising chlorine dioxideand gaseous by-products,condensing part of the gas withdrawn to obtain a condensate; and removing thecondensate from the non- condensed gas without re-circulating it back to the process for production of chlorine dioxide.
Patent CA-2776605-A1 (CA)
Title: Virtual channel table for a broadcast protocol and method of broadcasting and receiving broadcast signals using the same
Inventor: KIM JIN PIL
IPC: H04N7/08
Filed: 2000-10-06
Abstract: A virtual channel table for broadcasting protocol and a method for broadcasting by using the virtual channel table includes identification information identifying and permitting discrimination of active and inactive channels contained in the virtual channel table. At a receiver, the virtual channel table transmitted from the transmitting side is parsed, thereby determining whether the current received channel is an active or inactive channel.
Patent CA-2776928-A1 (CA)
Title: Unplugged bubble beverage machine
Inventor: WANG TEH-HSIN
IPC: A23L2/54
Filed: 2012-05-09
Abstract: An unplugged bubble beverage machine is disposed with a containing chamber and a cover body capable of sealing the containing chamber, wherein the cover body is disposed with a vent communicating with the containing chamber to contain the relief device. An interval is disposed between the vent and the relief device. The relief device can be pushed by gas inside the containing chamber to vertically move inside the vent, thereby achieving the effect of leaking gas inside the containing chamber.
Patent CA-2777845-A1 (CA)
Inventor: SCHWAEBLE HANS-WILHELM
IPC: A61K39/395
Filed: 2010-10-15
Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. In one embodiment, the invention provides methods of treating a subject suffering from a complement mediated coagulation disorder, such as disseminated intravascular coagulation. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (Clq-dependent) pathway component of the immune system intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier.
Patent CA-2778282-A1 (CA)
Title: Mobile communication terminal, mobile communication controller, mobile communication system, and mobile communication method
Inventor: AOYAGI KENICHIRO
IPC: H04M11/00
Filed: 2010-10-20
Abstract: A communication terminal device (10) is constituted such that when the communication terminal device is within the range of a first communication system, a control signal indicating a desire to transit to a second communication system is transmitted to the first communication system before a communication resource of the second communication system is obtained. The first communication system releases the communication resource of the first communication system in response to the control signal indicating the desire to transit to the second communication system even before the communication resource of the second communication system is obtained.
Patent CA-2780878-A1 (CA)
Title: Multi-piece stand for mobile computing device
Inventor: SUCKLE MITCHELL
IPC: A47G29/00
Filed: 2010-10-14
Abstract: Some embodiments teach a computing device accessory for a computing device. The computing device accessory can include: (a) a base having: (1) a base plate configured to rest on a surface; and (2) a base rear support coupled to the base plate at a first angle; (b) a top support having: (1) a top plate; and (2) a top rear support coupled to the top plate at a second angle; and (c) a connector collar configured to removably couple to the base rear support of the base and the top rear support of the top support. The top support can be configured to support the computing device such that the computing device is operable by a user when the base plate rests on the surface, the base rear support of the base and the top rear support of the top support are coupled to the connector collar. Other embodiments and methods are also disclosed herein.
Patent CA-2781495-A1 (CA)
Inventor: KNUST HENNER
IPC: C07D405/14
Filed: 2010-12-14
Abstract: The present application relates to compounds of formula (I) wherein R1 is hydrogen, halogen, cyano, lower alkyl or lower alkyl substituted by halogen; n is 1, 2 or 3, if n is 2 or 3, R1 can be different; R2 is C2-7-alkyl or C3-6-cycloalkyl; R3 is the group (II) wherein X is CH or N; R5 is hydrogen, -C(O)-lower alkyl, -C(O)O-lower alkyl, S(O)2-lower alkyl, -C(O)CH2O-lower alkyl, -C(O)-CH2-CN, or is - or -C(O)-cycloalkyl, cycloalkyl, or -CH2-cycloalkyl, wherein the cycloalkyl groups are optionally substituted by lower alkyl, -CH2-O-Iower alkyl, lower alkoxy, CF3, halogen or cyano, or is -C(O)-heterocycloalkyl or heterocycloalkyl, or is -C(O)-heteroaryl or is heteroaryl or is -C(O)-aryl or aryl, which heterocycloalkyl, heteroaryl or aryl groups are optionally substituted by halogen, lower alkyl, =O, lower alkoxy, lower alkyl substituted by halogen, lower alkyl substituted by hydroxy, -C(O)-CH2-N(di-lower alkyl), C(O)NH-lower alkyl, C(O)NH2, -O-C(O)- lower alkyl, C(O)-lower alkyl, S(O)2-lower alkyl or cyano; R4 is aryl, which is optionally substituted by halogen, hydroxy, lower alkyl, lower alkyl substituted by halogen, S(O)2-lower alkyl, cyano or by lower alkoxy; or to a pharmaceutically active salt thereof. It has been found that the present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
Patent CA-2782040-A1 (CA)
Title: Melange de gaz comprime
Inventor: COHEN JOSEPH PERRY
IPC: B01F23/10
Filed: 2012-06-29
Abstract: Un système de distribution de gaz comprimé et un procédé associé où les gaz comprimés sont extraits des contenants de stockage de gaz comprimé, envoyés dans des régulateurs de débit régulés et des tubes de venturi à écoulement critique pour contrôler les débits massiques des gaz comprimés formant le mélange de gaz comprimés avant de distribuer le mélange.
Patent CA-2783867-A1 (CA)
Inventor: RICO DAN
IPC: G06T7/00
Filed: 2009-12-22
Abstract: The invention provides a system and method for processing medical images. Input medical images are normalized first, utilizing pixel intensities of control point tissues, including subcutaneous fat. Clustered density map and malignance probability map are generated from a normalized image and further analyzed to identify regions of common internal characteristics, or blobs, that may represent lesions. These blobs are analyzed and classified to differentiate possible true lesions from other types of non-malignant masses often seen in medical images.
Patent CA-2784659-A1 (CA)
Title: Ready-to-bake batter and methods of making the same
Inventor: ECKSTROM ELEANORE BROPHY
IPC: A23L9/10
Filed: 2012-08-02
Abstract: A ready-to-bake batter and method for manufacture are provided. The method includes the steps of: combining cream cheese, cream, sweetener, and eggs to form a mixture; heating the mixture to at least 140°F to create a heated mixture; injecting an inert gas into the heated mixture; aerating the heated mixture; and cooling the heated mixture to form a batter. The batter is stable when stored for over 120 days such that when baked, the batter provides a cake similar to a fresh made-from-scratch cake.
Patent CA-2785101-A1 (CA)
Inventor: MARLIERE PHILIPPE
IPC: C12P5/02
Filed: 2009-12-22
Abstract: Described is a method for the enzymatic production of isoprenol using mevalonate as a substrate and enzymatically converting it by a decarboxylation step into isoprenol as well as the use of an enzyme which is capable of catalyzing the decarboxylation of mevalonate for the production of isoprenol from mevalonate. Furthermore described is the use of mevalonate as a starting material for the production of isoprenol in an enzymatically catalysed reaction. Also disclosed is a method for the production of isoprene comprising the method for the production of isoprenol using mevalonate as a substrate and enzymatically converting it by a decarboxylation step into isoprenol and further comprising the step of converting the produced isoprenol into isoprene as well as a method for the production of isoamyl alcohol comprising the method for the production of isoprenol using mevalonate as a substrate and enzymatically converting it by a decarboxylation step into isoprenol and further comprising the step of converting the produced isoprenol into isoamyl alcohol.