baber/WOPTO huggingface dataset:
Patent NZ-516170-A (NZ)
Title: Erythropoietin conjugates with polyethylene glycol
Inventor: BURG JOSEF
IPC: A61K47/48
Filed: 2000-06-28
Abstract: Erythropoietin glycoprotein conjugates are disclosed, said conjugates comprise an erythropoietin glycoprotein having at least one free amino group and having the in vivo biological activity of causing bone marrow cells to increase production of reticulocytes and red blood cells and selected from the group consisting of human erythropoietin and analogs thereof which have the primary structure of human erythropoietin modified by the addition of from 1 to 6 glycosylation sites or by the rearrangement of at least one glycosylation site; said glycoprotein being covalently linked to form one to three lower-alkoxy poly(ethylene glycol) groups, each poly(ethylene glycol) group being covalently linked to the glycoprotein via a linker of the formula -C(O)-X-S-Y- with the C(O) of the linker forming an amide bond with one of said amino groups, wherein X and Y are as defined in the description and claims, the average molecular weight of each poly(ethylene glycol) moiety is from about 20 kilodaltons to about 40 kilodaltons, and the molecular weight of the conjugate is from about 51 kilodaltons to about 175 kilodaltons.
Patent NZ-516223-A (NZ)
Title: Use of growth hormone (hGH) for the treatment of sexual dysfunction
Inventor: BECKER ARMIN JOHANNES
IPC: A61P15/10
Filed: 2000-06-15
Abstract: Growth hormone can be used for the manufacture of a medicament for treating female and males with sexual functional disorder without neurogenic erectile dysfunctional in cases of insufficient increase in hGH concentration during sexual stimulation and for those with hGH deficiency. The sexual functional disorder could be the lack or loss of libido, problems relating to orgasms, insufficient lubrication and/or erectile dysfunction.
Patent NZ-522666-A (NZ)
Title: Formulation and process for producing a universal fruit base for use in preparing non-settling, creamy, smooth, thick fruit beverages
Inventor: FACON MICHEL
IPC: A23L19/00
Filed: 2001-05-04
Abstract: A process of producing a non-frozen universal fruit base from apples suitable for the production of a smooth apple- based fruit beverage which comprises: (a) washing and sanitizing the apples; (b) cutting the apples into pieces; (c) cooking the apple pieces with steam at a temperature between 100°C and 110°C for about 2 to about 8 minutes so that the steam breaks down the water-insoluble protopectin in the middle lamellae of the apple to water-dispersible pectins, inactivates polyphenol oxidase in the apple foe the prevention of enzymic browning, inactivates other oxidases in the apple to inhibit the oxidation of ascorbic acid, gelatinizes the protoplasts in the apple to bring about elastic, semi-solid protoplasts in the intact apple cells, plasticizes the apple cell walls to enhance extensibility and resistance to impact fractures, and exposes the adhesive surfaces of intact apple cells; (d) macerating and screening the cooked apple pieces with a finisher/pulper having screen openings between about 0.05 and 0.13 inches to produce an apple mince; (e) comminuting the apple mince with a comminutor having screen openings between 0.033 and 0.093 inches to produce and apple mash having predominantly intact single cells; and (f) adding a pregelatinized cross-linked high amylopectin maize starch and xanthan gum to the apple mash to produce a universal fruit base.
Patent NZ-524053-A (NZ)
Title: Overflowing soaker bath tub
Inventor: SWART PETER W
IPC: A61M21/02
Filed: 2001-06-25
Abstract: Disclosed herein is a bath tub (10) having a deep basin (12) without an internal overflow. Instead, an overflow trough (14) encircles the basin and collects water falling over a rim of the basin. A pump (64) directs water within the overflow trough through a conduit back into the basin, so as to continuously maintain water flowing over the rim of the basin. Micro-effervescence and a chromatherapy system can also be provided with such a tub.
Patent NZ-524852-A (NZ)
Title: New thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors
Inventor: VERGNE FABRICE
IPC: A61K31/55
Filed: 2001-10-01
Abstract: Disclosed are compounds of formula (I), wherein: Y is O or S, R1 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocycle, aryl or bicyclic group, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases mediated by a phosphodiesterase 7 (PDE7) inhibitor.
Patent NZ-529386-A (NZ)
Title: Fertilizer and water mixing method for irrigation to soil
Inventor: COSGROVE KEVIN
Filed: 2003-11-07
Abstract: Disclosed is a method of bulk mixing a dry particulate material and a liquid to form an aqueous solution using a mixing unit that includes an exterior tank (52), an interior tank (51) that is situated at least partially within the exterior tank and drains liquid into the exterior tank via one or more apertures, and a recycle loop (59, 60, 62) including a pump (61) for conveying liquid from the base of the exterior tank into the top of the interior tank configured such that the flow rate of liquid through the recycle loop is sufficient to create a turbulent environment in the interior tank.
Patent NZ-536134-A (NZ)
Title: A low voltage electricity distribution circuit which supplies both switchable and unswitchable power from power sources
Inventor: KIM KYUNG TAE
IPC: H02B1/056
Filed: 2003-04-04
Abstract: The low voltage electricity distribution circuit of the present invention is an electrical outlet that includes a receptacle mounted to a recess including either a plurality of wires or a bus bar system. The receptacle has at least one continuously live power socket and at least one switched power socket disposed on it. Each of the power sockets is capable of receiving an appliance plug. The receptacle is movable along the recess to a different location to allow for appliances, for example lamps or computers, to be located at many different points along the wall. In other forms of the distribution circuit a stand-along unit that is fixed in place may be provided.
Patent NZ-538296-A (NZ)
Title: Indole derivatives or benzimidazole derivatives for modulating IkB kinase
Inventor: RITZELER OLAF
IPC: A61P1/02
Filed: 2003-08-05
Abstract: Disclosed herein are indole derivatives or benzimidazole derivatives, processes for preparing such compounds, pharmaceutical compositions comprising such compounds. Particularly disclosed are compounds of formula (I) that are suitable for the prophylaxis and therapy of a disease associated with an increased activity of IkappaB (IkB) kinase; wherein the variables shown in formula (I) are as defined in the specification.
Patent NZ-538839-A (NZ)
Title: Efficient algorithm and protocol for remote differential compression
Inventor: TEODOSIU DAN
IPC: H04N7/42
Filed: 2005-03-15
Abstract: This system is for updating objects over a network between a local device and a remote device. A means computes a first fingerprint function at every byte offset of a first object on the remote device. A means chunks the first object on the remote device based on the first fingerprint function. Another means computes a remote signature for each chunk associated with the first object on the remote device. A means generates a remote signature and chunk length list on the remote device. The remote signature and chunk length list is associated with the first object. A means computes a second fingerprint function at every byte offset of a second object on the local device. The first and second objects are associated with one another, and where the first fingerprint function is matched to the second fingerprint function. A means chunks the second object on the local device based on the second fingerprint function. The means for chunking the first object on the remote device is matched to the means for chunking the second object on the local device; A means computes a local signature for each chunk associated with the second object on the local device. The means for computing the local signature is matched to the means for computing the remote signature. A means generates a local signature and chunk length list on the local device, wherein the local signature and chunk length list is associated with the second object. A means negotiates a chunked transmission of the remote signature and chunk length list from the remote device to the local device over the network such that bandwidth use is minimized for identifying differences between the first object and the second object by comparing the local signature and chunk length list to the remote signature and chunk length list on the local device. A means requests transmission of at least one updated object chunk from the remote device when differences between the first object and the second object are identified by the local device and a means transmits the at least one updated object chunk from the remote device to the local device over the network. A means reassemblies a copy of the first object on the local device with the at least one updated object chunk.
Patent NZ-540455-A (NZ)
Title: Use of the CRH (corticotropin releasing hormone) - UCN (urocortin) system in the treatment of specific inflammatory disease
Inventor: MARGIORIS ANDREW N
IPC: A61P29/00
Filed: 2003-11-26
Abstract: Disclosed is the use of one or more synthetic CRH-R1 antagonists and/or CRH-R2 agonists for the manufacture of a pharmaceutical composition for the treatment of an inflammatory disease or condition associated to activation, deactivation, differentiation and apoptosis of macrophages. The inflammatory disease or condition is selected from the group consisting of chronic inflammatory bowel disease, idiopathic inflammatory disorder, inflammatory disorders of connective tissue, inflammatory demyelinating polyneuropathies, inflammatory myopathies, inflammatory diseases of joints including bursitis, the fibromyalgia syndrome and inflammatory diseases of the gastrointestinal tract.
Patent NZ-544145-A (NZ)
Title: A blade wheel for removing bark from a tree trunk or branch
Inventor: SMYTHE JUSTYN PETER
Filed: 2005-12-13
Abstract: The present invention relates to a wheel for the removal of a surface layer from an item, the wheel having one or more primary blades oriented substantially across the direction of rotation with the wheel within operation, characterised in that the wheel includes a secondary cutting blade oriented substantially in the same direction as the direction of rotation with the wheel when in operation.
Patent NZ-546609-A (NZ)
Title: Resettable safety shield for medical needles
Inventor: SNOW JEREMY K
IPC: A61M5/00
Filed: 2004-11-23
Abstract: A medical needle shield apparatus is disclosed. The needle shield comprises: a needle hub (104) with a needle cannula (103) extending from there to a distal end; a retainer for releasable engagement with the needle hub (104), and at least one shield (101) which is extensible from a retracted position to an extended position to enclose a distal end of the needle. The shield (101) includes a binding member (105), which is disposed within the shield (101) and defines binding surfaces that form an aperture configured for slidable receipt of the needle between the retracted position and the extended position. The binding member (105) includes at least one drag inducing member so that the at least one drag inducing member engages the needle during slidable receipt of the needle to create a drag force with the needle. The drag force and shield facilitate rotation of the binding member (105) relative to a longitudinal axis of the needle so that the binding surfaces engage the needle to prevent slidable movement of the needle in the extended position of the shield. The binding member (105) further includes a needle communicating surface which extends from there so that the needle communicating surface can engage with the needle to prevent rotation of the binding member (105). The binding member (105) further includes a binding member reset surface (107) selectably alignable with a reset surface (108).
Patent NZ-549792-A (NZ)
Title: Compositions comprising drospirenone molecularly dispersed
Inventor: FUNKE ADRIAN
IPC: A61K9/107
Filed: 2005-03-10
Abstract: Disclosed is a solid or semi-sold composition adapted for oral administration comprising Drospirenone molecularly dispersed in at least one pharmaceutically acceptable carrier. Also disclosed is a process of preparing the above composition.
Patent NZ-555313-A (NZ)
Title: An expression vector encoding coronavirus-like particles
Inventor: HWU LUEN
Filed: 2004-11-26
Abstract: Disclosed is an expression vector encoding coronavirus-like particles, which comprises two transcriptional units, wherein the first unit comprises genes encoding membrane M protein and envelope E protein from coronavirus, while the second unit comprises SpikeCT coding gene from coronavirus. Said expression vector is useful for cloning viral genes from Type I membrane fusion mechanism, and also is useful as DNA vaccine candidate.
Patent NZ-560252-A (NZ)
Title: Novel pyrimidine nucleoside compound or its salt
Inventor: ONO YAYOI
IPC: A61K31/7068
Filed: 2006-01-30
Abstract: Disclosed are 2'-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine derivatives or a salt thereof represented by the formula (1), wherein one of X and Y represents a cyano group, and the other represents a hydrogen atom; one of R1 and R2 represents a hydrogen atom, a carbonyl group having a C1-C6alkyl group which has been mono-substituted by an amino group or a group represented by (R3)(R4)(R5)Si-, and the other represents a group represented by (R6)(R7)(R8)Si-, or R1 and R2 together form a six-membered cyclic group represented by -Si(R9)(R10) -, where the other substituents are defined herein. Also disclosed is a drug composition which contains an effective amount of a pyrimidine nucleoside compound as defined above or a salt thereof and a pharmaceutically acceptable carrier. Additionally, the use of a pyrimidine nucleoside compound as defined above for production of a drug for use as an anti-tumor agent is also disclosed.
Patent NZ-567841-A (NZ)
Title: Methods and compositions for the enzymatic synthesis of gangliosides
Inventor: DEFREES SHAWN
IPC: C07H15/26
Filed: 2004-03-04
Abstract: Provided are specified glycosphingolipid ganglioside compounds and methods of producing them synthetically in vitro. The compounds are of interest to treat neurological and autoimmune diseases. (62) Divided Out of 542148
Patent NZ-569117-A (NZ)
Title: Agent comprising 5-D-fructose dehydrogenase for use in the case of fructose intolerance
Inventor: WYROBNIK DANIEL HENRY
IPC: A23L33/20
Filed: 2006-11-15
Abstract: Disclosed is the use of a 5-D-fructose dehydrogenase for the manufacture of a medicament for the therapy or diagnosis of fructose intolerance. Further disclosed are pharmaceutical compositions, foodstuffs and human ingestible compositions comprising 5-D-fructose dehydrogenase.
Patent NZ-569241-A (NZ)
Title: Trap with pivotting closure with transverse movement of closure to prevent further pivotting
Inventor: CAMMILLERI CRAIG FREDERICK
IPC: A01K69/08
Filed: 2006-11-23
Abstract: Ballasted (25) trap (21) is moulded of high-density plastics to safely confine an animal (e.g. an octopus). The animal enters trap (21) via entrance (15), as closure (43) is then open. By tugging at lure (57) it slackens inextensible cord (51) attached to an upper portion of door (43). This action allows elastic cord (49) to cause door (43) to swing closed, about pivot pins (45). Cord (49) continues biasing door (43) during which motion upper edge of door (43) slides against arcuate guide surface (37). On reaching the closed position, however, as the pivot pins (45) are located in slot in the wall of trap (11), door (43) is further biased to slide upwardly to engage slot (39), thereby locking door (43) closed.
Patent NZ-574011-A (NZ)
Title: Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient
Inventor: KOHNO YASUSHI
IPC: A61P35/00
Filed: 2007-08-07
Abstract: Disclosed are amino phosphate derivative represented by the general formula (la), wherein R3 represents a straight-chain alkyl group having 1 to 3 carbon atoms, X represents an oxygen atom or a sulphur atom, and n denotes 2 or 3, or a pharmaceutically acceptable salt or hydrate thereof. Of particular importance are the compounds (R)-2-amino-5- [2-chloro-4-(3-trifluoromethylphenoxy)phenyl]-2-methylpentyl phosphoric acid monoester, (R)-2-amino-5-[2-chloro-4-(3-trifluoromethylphenylthio)phenyl]-2-methylpentyl phosphoric acid monoester, (R)-2-amino-4-[2-chloro-4-(3-trifluoromethylphenoxy)phenyl]-2-methylbutyl phosphoric acid monoester, (R)-2-amino-4-[2-chloro-4-(3-trifluoromethylphenylthio)phenyl]-2-methylbutyl phosphoric acid monoester, (R)-2-amino-5-[2-chloro-4-(3-trifluoromethylphenylthio)phenyl]-2-propylpentyl phosphoric acid monoester. Further disclosed is an S1P receptor modulator which comprises an amino phosphate derivative as defined above as an active ingredient for treating or preventing rejection of heart transplants, kidney transplants, skin grafts, liver transplants, bone marrow transplants, rheumatoid arthritis, lupus nephritis , systemic lupus erythematosus , Hashimoto's disease, multiple sclerosis, myasthenia gravis, diabetes mellitus, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, or allergic contact dermatitis.
Patent NZ-577976-A (NZ)
Title: Sp35 antibodies and uses thereof
Inventor: MI SHA
IPC: A61K39/00
Filed: 2008-01-09
Abstract: Disclosed is an isolated antibody or antigen-binding fragment thereof which can specifically bind to an Sp35 polypeptide, wherein the antibody or fragment thereof comprises: (i) an immunoglobulin heavy chain variable region comprising VH CDR1, CDR2, and CDR3 regions identical, except for less than 4 conservative amino acid substitutions, to the VH CDR1, CDR2, and CDR3 sequences of SEQ ID NO:436, SEQ ID NO:437 and SEQ ID NO:438; and (ii) an immunoglobulin light chain variable region comprising SEQ ID NO:442, SEQ ID NO:443, and SEQ ID NO:444 comprising VL CDR1, CDR2, AND CDR3 regions identical, except for less than 4 conservative amino acid substitutions to the VL CDR1, CDR2, and CDR3 sequences of SEQ ID NO:442, SEQ ID NO:443 and SEQ ID NO:444, respectively.
Patent NZ-583242-A (NZ)
Title: Pharmaceutical composition comprising a glucopyranosyl-substituted benzene derivative
Inventor: DUGI KLAUS
IPC: A61K31/00
Filed: 2008-08-15
Abstract: Disclosed is a pharmaceutical composition comprising the glucopyranosyl-substituted benzene derivative 1-chloro-4-(beta-D-glucopyranos-1-yl)-2-[4-(S)-tetrahydrofuran-3-yloxy)benzyl]-benzene, either, in combination with the DPP IV inhibitor 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine, or its pharmaceutically acceptable salt; or, in combination with a DPP IV inhibitor selected from the group consisting of sitagliptin, vildagliptin, saxagliptin, alogliptin, denagliptin, (2S)-1-{ [2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethylamino]-acetyl} -pyrrolidine-2-carbonitrile, (2S)-1-{ [1,1,-Dimethyl-3-(4-pyridin-3-yl-imidazol-1-yl)-propylamino]-acetyl} -pyrrolidine-2-carbonitrile, (S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-one, (3,3-Difluoropyrrolidin-1-yl)-((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, (1((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-yl)-1,3,5-triazin-2-yl)pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one, (2S,4S)-1-{ 2-[(3S,1R)-3-(1H-1,2,4-Triazol-1-ylmethyl)cyclopentylamino]-acetyl} -4-fluoropyrrolidine-2-carbonitrile, and (R)-2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile. Also disclosed is the use of the composisiton in the manufacture of a medicament for preventing, slowing the progression of, delaying or treating a metabolic disorder selected from the group consisting of type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance, impaired fasting blood glucose, hyperglycemia, postprandial hyperglycemia, overweight, obesity and metabolic syndrome.
Patent NZ-584657-A (NZ)
Title: Fiber reinforced plastic composites with longitudinal and transverse reinforcing fibres where at least some of the transverse fibres are curved at their ends along the ends of the product
Inventor: PAUL KERMIT D
IPC: B29C48/30
Filed: 2008-10-30
Abstract: 584657 A fibre reinforced plastic resin product having delamination resistant edges, comprises a substantially flat product made by a pultrusion process including reciprocating consolidation plates 45, 47. The product has longitudinal and transverse reinforcing fibres 53, where at least some of the transverse fibres 53 are curved at their ends along the edge of the product and extend to the vicinity of the centre of the edge as a result of excess resin being forced from between the reciprocating consolidator plates 45, 47 during shaping into a flashing 55 which is later removed.
Patent NZ-584806-A (NZ)
Title: Soft shaped tortilla which is sufficiently rigid to maintain its shape at room temperature
Inventor: GRIEBEL JONATHAN M
IPC: A23P1/10
Filed: 2010-04-21
Abstract: A packaged food article and a method of preparing a food article. The packaged food article includes a hermetically sealed food package with a headspace filled with a headspace gas. The packaged food article also includes a baked soft shaped tortilla piece with a thickness ranging from about 1-5 mm and a water activity of 0.88 or less. The soft shaped tortilla piece has a shape other than flat and is both pliable and sufficiently rigid to maintain its shape at room temperature.
Patent NZ-586419-A (NZ)
Title: Apparatus for receiving an information medium locatable on back of seat with insert with tongue located in recessed plate
Inventor: BERGER GEORG
IPC: B60N2/90
Filed: 2010-06-24
Abstract: The present disclosure relates to an apparatus, in particular for attaching to the back of a seat. The apparatus comprises a plate with a flat recess and an insert which is removably mountable in the flat recess of the plate and is configured to hold an information medium which is viewable when the insert is mounted in the flat recess of the plate. For the detachable fixing of the insert on mounting of the same in the flat recess, the insert has the following: at least one tongue on a first border area of the insert for engagement in at least one correspondingly shaped groove in the plate, and at least one detachable fixing apparatus that is present in or on at least one second border area of the insert and that is operable by twisting and/or sliding at least one component.
Patent NZ-590136-A (NZ)
Title: Using photosynthesis of plants to remove carbon dioxide from gases
Inventor: AMADESI PAOLO
IPC: A01G9/18
Filed: 2009-07-03
Abstract: 590136 Disclosed is an apparatus (1) for reducing the carbon dioxide contained in combustion smokes. The apparatus comprises at least one smoke inlet conduit (2) inside at least one operating chamber (3) and at least one ejection conduit (4) for the gases treated. The at least one chamber (3) comprises at least one plant (10) arranged along the smoke path between the inlet conduit (2) and the ejection conduit (4). The smokes strike the plant (10) surfaces during their circulation.