baber/WOPTO huggingface dataset:
Patent DE-69033848-D1 (DE)
Inventor: SHINMEN YOSHIFUMI
IPC: A23L1/30
Filed: 1990-07-20
Granted: 2001-12-13
Abstract: Use of a dioxabicylclo[3.3.0]octane compound represented by the following general formula (I):wherein groups R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup> and R<sup>6</sup> are selected independently from hydrogen atom and C<sub>1-3</sub> alkyl groups, provided that R<sup>1</sup> and R<sup>2</sup> and/or R<sup>4</sup> and R<sup>5</sup> may together form a methylene or ethylene group, andn, m and ℓ are 0 or 1,   in the preparation of a medicament to improve liver function, to reduce cholesterol level or to reduce neutral fat level.Suitable compounds include sesamin, sesaminol, episesamin, episesaminol, sesamolin, 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo-[3.3.0]octane, 2,6-bis-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane and 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-hydroxyphenoxy)-3,7-dioxabicyclo[3.3.0]octane.
Patent DE-69106977-D1 (DE)
Inventor: ROBERTS DAVID ANTHONY
IPC: C07D403/10
Filed: 1991-08-05
Granted: 1995-03-09
Abstract: The invention provides a novel process for the manufacture of biphenylcarbonitriles of the formula III as defined hereinafter which are useful for the production of certain known imidazole derivatives and certain novel quinoline derivatives which have angiotensin II inhibitory activity. The process involves a palladium- or nickel-catalysed reaction of a boron compound of the formula II with a nitrile of the formula III in which the variables L<1>, L<2>, Q<1> and Q<2> have the various meanings defined hereinafter. Certain of the biphenylcarbonitriles are novel and are provided as a further feature of the invention. The invention also provides a novel process for the production of the known and novel angiotensin II inhibitors of formula VI and VII as defined hereinafter.
Patent DE-69115706-D1 (DE)
Inventor: ROSENTHAL ROBERT
IPC: G01N21/35
Filed: 1991-09-11
Granted: 1996-02-01
Abstract: A method and means for generating synthetic spectra allowing quantitative measurement utilizes dual chip alternatively energized IREDs with optical bandpass filter(s) passing two optical bands which could be combined with curvilinear interpolation to be utilized in a low cost small size quantitative measuring instrument.
Patent DE-69119412-D1 (DE)
Inventor: BROWN ROBERT
IPC: B26B21/52
Filed: 1991-03-21
Granted: 1996-06-13
Abstract: A hand-held razor of the wet-shave type includes a thin flexible foil member with a plurality of apertures, each of which has opposed sharpened shaving edge portions. A displacing mechanism cyclically displaces the foil along a predetermined path such that the velocity of the opposed edge portions caused by the mechanism is substantially greater than the speed of motion caused by normal shaving stroke manipulation. The amplitude of each displacement cycle is greater than the width of a beard hair and less than the distance between the oppoosed edge portions.
Patent DE-69120118-D1 (DE)
Inventor: TOPSOE HALDOR FREDERIK AXEL
IPC: C07C29/151
Filed: 1991-03-18
Granted: 1996-07-18
Abstract: The invention comprises a method of preparing methanol by reacting synthesis gas comprising hydrogen and carbon oxides (CO, CO2) in a fixed bed methanol synthesis catalyst, the improvement of which comprises reacting the synthesis gas at reaction conditions, where condensation of methanol occurs on the catalyst. <IMAGE>
Patent DE-69123137-D1 (DE)
Inventor: MANN DAVID
IPC: F16F1/371
Filed: 1991-09-06
Granted: 1996-12-19
Abstract: The present invention relates to a fail safe resilient mount which includes an outer dome shaped member having an aperture centered about an apex thereof and oppositely diposed ears extending therefrom, an inner bell shaped member axially offset from said outer member having a centered aperture at a top thereof and a locking member therein and an elastomeric material encapsulating and bonded to a domed portion of the outer member and encapsulating and bonded to the inner member and interposed between an inner surface of the outer member and an outer surface of the inner member.
Patent DE-69130760-D1 (DE)
Inventor: TANAKA MASAHIDE
IPC: C10M105/48
Filed: 1991-09-13
Granted: 1999-02-25
Abstract: The polycarbonates of the present invention include those having a skeletal structure of pentaerythritol, neopentyl glycol or trimethylolmethane, and specific dicarbonates. The lubricating oil and electrical insulating oil of the invention contain the above-mentioned polycarbonates. The polycarbonates of the invention are excellent in compatibility with Freon R-134a (HFC) as well as in lubricating properties, detergency and electrical insulating properties, and are capable of providing lubricating oil for refrigerator, automotive engine oil, automotive gear oil, lubricating oil for rolling and lubricating oil for fiber, especially lubricating oil for which electrical insulating properties are required, and electrical insulating oil.
Patent DE-69200335-D1 (DE)
Inventor: TAGNON CLAUDE JEAN-MARIE
IPC: F24F13/06
Filed: 1992-01-20
Granted: 1994-09-22
Abstract: A diffuser for diffusing a turbulent jet of air along a vertical axis (yy') comprises a cylindrical casing (1) having a top face (3) with an axial air flow inlet opening (11), and a bottom face (5). The top (3) and bottom (5) faces of the cylindrical casing (1) are two identical polygons having a sawtooth outline, defining tooth flanks therebetween, a first flank (9) of a tooth being substantially perpendicular to the second flank (7) of an adjacent tooth, said first flank consisting of a wall providing substantially tangential deflection of the air, and the second flank constituting an air outlet orifice (7) directed substantially radially with respect to the casing (1). The bottom face (5) of the casing (1) is without openings.
Patent DE-69205417-D1 (DE)
Inventor: WESSELING KAREL HENDRIK
IPC: A61B5/029
Filed: 1992-01-28
Granted: 1995-11-16
Abstract: PCT No. PCT/NL92/00022 Sec. 371 Date Sep. 20, 1993 Sec. 102(e) Date Sep. 20, 1993 PCT Filed Jan. 28, 1992 PCT Pub. No. WO92/12669 PCT Pub. Date Aug. 6, 1992.Method of determining the stroke volume of the human heart from the pulse-type blood-stream pressure signal derived from the aorta and consisting in each case of a systolic and a diastolic period. The method comprises calculating the flow q(t) from the pressure p(t) and integrating the flow over the systolic period, the aorta being regarded as a transmission line supplemented with a windkessel compliance and the pressure/volume relationship in the aorta as an arctangent relationship. The pressure represented by the pressure signal-for each stroke prior to the calculation of the flow-is linearized by the arctangent relationship, for fixed aorta length, or the aorta pressure/cross section, the values, associated with the final diastolic pressure, of the characteristic impedance of the transmission line and windkessel compliance being adhered to or is used without modification. The characteristic impedance of the transmission line and the windkessel compliance are continuously adapted to the pressure of the windkessel compliance for each stroke concerned. Additionally, to calculate the flow, the flow through the peripheral resistance is added.
Patent DE-69205641-D1 (DE)
Inventor: EDYE THOMAS
IPC: B60R21/205
Filed: 1992-08-03
Granted: 1995-11-30
Abstract: In order to be able to equip the vehicle with a single inflatable cushion (air bag) arranged, when it is not inflated, in a housing (13) made over the entire width of the dashboard of the vehicle and protecting both the driver of the vehicle and a passenger seated beside him in the event of an accident, the control system for steering this vehicle comprises a lever (11) which can be moved in a plane and replaces the steering wheel of conventional vehicles. An electronic circuit slaves the angular position of the wheels of the vehicle to the position of this lever (11). <IMAGE>
Patent DE-69205844-D1 (DE)
Inventor: WISE ROGER JEREMY
IPC: C08J5/12
Filed: 1992-01-16
Granted: 1995-12-14
Abstract: A method of joining members comprises applying a thermoplastic coating (6) to the surface of at least one of the members (8,11). This coating (6) is applied by applying a solution onto the surface and the two members (8,11) are joined via their coatings. This method is particularly suitable for joining dissimilar materials e.g. metals and thermoplastics. <IMAGE>
Patent DE-69213855-D1 (DE)
Inventor: PEREGO GIANLUCA
IPC: F16H3/083
Filed: 1992-07-16
Granted: 1996-10-24
Abstract: A mechanical transmission (10) in particular for toy automobiles comprises a substantially cylindrical element (19) rotating axially in kinematic connection with the motion output (22) of the transmission. On said cylindrical element (19) are fitted in a rotating manner toothed gears (17,18) each of which is in kinematic connection at a different ratio with the motion input of the transmission. Inside the cylindrical element (19) is axially sliding between the gears (17,18) by control means (26) a cursor (24) for selective sequential radial engagement between the cylindrical element (19) and the gears (17,18) so as to realize motion transmission with a different ratio between input and output through selection of engagement between the cylindrical element and a gear. <IMAGE>
Patent DE-69220287-D1 (DE)
Inventor: ADAMS STEVEN PAUL
IPC: A61P25/28
Filed: 1992-04-23
Granted: 1997-07-17
Abstract: Novel short peptides of up to about 20 amino acid residues are disclosed that bind to the SEC receptor. These novel peptides preferably are pentapeptides which are synthetic analogs of a pentapeptide domain in the carboxy-terminal fragment of  alpha 1-antitrypsin (amino acids 370-374, Phe-Val-Phe-Leu-Met [SEQ ID NO:2]). A preferred binding peptide is Phe-Val-Ala-Leu-Met [SEQ ID NO:6].
Patent DE-69229047-D1 (DE)
Inventor: FORMAN THOMAS
IPC: F01D5/28
Filed: 1992-03-09
Granted: 1999-06-02
Abstract: A multi-vane structure for incorporation in an aircraft gas turbine engine has vanes of complex geometry made of braided fibers which are continuous about the cavities defined by the vanes. These complex geometry parts are prepared by providing a plurality of removable mandrels, stacking the mandrels along a horizontal axis in a cavity end to cavity end configuration, braiding about the mandrels, cutting the mandrels adjacent the cavity end faces, side stacking the mandrels so the faces are placed in a parallel orientation and molding. Utilizing braided fibers instead of hand lay-up woven fibers eliminates seams and produces cavities having continuous fibers about the periphery thereof which substantially increases the strength and dimensional reproducibly of the part.
Patent DE-69307333-D1 (DE)
Inventor: MARGRAFF RODOLPHE
IPC: C07B63/00
Filed: 1993-10-04
Granted: 1997-02-20
Abstract: This invention relates to a process for obtaining 10-deacetylbaccatin III from various parts of yew (Taxus sp.) by extraction with a suitable organic solvent of the aqueous solution obtained after treating the appropriate part of yew with water, followed by selective crystallization of 10-deacetylbaccatin III.
Patent DE-69310913-D1 (DE)
Inventor: SADAN ABRAHAM
IPC: C01F5/40
Filed: 1993-11-10
Granted: 1997-06-26
Abstract: A simple, efficient and inexpensive method of purifying magnesium sulfate from mixtures of epsomite and halite. The method allows for the preparation of substantially pure magnesium sulfate products. The method generally involves heating a mixture of epsomite and halite to form clusters of lower hydrated magnesium sulfate crystals and subsequently applying slight pressure to the clusters so that they collapse to yield fine, less hydrated magnesium sulfate crystals which can then be easily separated from the comparatively coarse halite crystals. The less hydrated magnesium sulfate crystals can be recrystallized to provide highly purified epsomite which can then be dehydrated to provide kieserite or anhydrous magnesium sulfate.
Patent DE-69318312-D1 (DE)
Inventor: HUTCHINSON RAY
IPC: G01M3/26
Filed: 1993-12-07
Granted: 1998-06-04
Abstract: An improved method for detecting small leaks in underground pressurized piping systems is disclosed. In particular, the method comprises the steps of taking pressure measurements over identical time intervals from a product line at a pressure above the pump discharge pressure while the product pump is running. Thereafter, the absolute value of the difference between successive pressure decays is calculated and compared to an acceptable value. Next, the value of the latest pressure decay value is compared to acceptable and unacceptable values reflecting acceptable and unacceptable tightness of the product line.
Patent DE-69329467-D1 (DE)
Inventor: NILSSON PER
IPC: B66C17/00
Filed: 1993-02-02
Granted: 2000-10-26
Abstract: PCT No. PCT/SE93/00080 Sec. 371 Date Jul. 22, 1994 Sec. 102(e) Date Jul. 22, 1994 PCT Filed Feb. 2, 1993 PCT Pub. No. WO93/15705 PCT Pub. Date Aug. 19, 1993.A method and apparatus for transferring a load (8) carried by a carrier member (12) between two mutually separate transport paths (3a, b). During transfer, the carrier member switches from being suspended by a device (4a) displaceable in the first carrier path (4a) to being suspended by a device (4b) displaceable in the second carrier path (3b). The carrier member (12) when it is suspended by a first connecting device (9a, 11a) from the displaceable device (4a) of the first conveyor path (4a), is connected to the displaceable device (4b) of the second conveyor path (3b) by a second connecting device (9b, 11b). The length of the second connecting device is reduced and the carrier member (12) is displaced thereby so as to be wholly suspended from the displacement device (4b) of the second conveyor path. A drive mechanism lengthens or shortens at least one of the connecting devices in relation to a housing (14) for modifying the distance between the carrier member (12) and the displaceable devices (4a, 4b).
Patent DE-69409652-D1 (DE)
Inventor: VAN LOMMEN GUY
IPC: C07D405/12
Filed: 1994-08-12
Granted: 1998-05-20
Abstract: PCT No. PCT/EP94/02702 Sec. 371 Date Feb. 5, 1996 Sec. 102(e) Date Feb. 5, 1996 PCT Filed Aug. 12, 1994 PCT Pub. No. WO95/05366 PCT Pub. Date Feb. 23, 1995The present invention is concerned with compounds having the formula    <IMAGE>  (I)  the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric forms thereof, wherein R1 is hydrogen or C1-6alkyl; R2 is hydrogen or C1-6alkyl; R3 is C1-6alkyl, hydroxy, cyano, halo, C1-6alkyloxy, aryloxy, arylmethoxy, C2-6alkenyl, C2-6alkynyl, C1-6alkyl-S-, C1-6alkyl(S=O)-, C1-6alkylcarbonyl; R4 is hydrogen, halo, hydroxy, C1-6alkyl, or C1-6alkyloxy; or R3 and R4 taken together form a bivalent radical; R5 and R6 each independently are hydrogen, halo, hydroxy, C1-6alkyl, C1-6alkyloxy, aryloxy or arylmethoxy; R7 is hydrogen; Alk1 is C2-5alkanediyl; Alk2 is C2-15alkanediyl; Q is a heterocyclic ring containing at least one nitrogen atom or a radical of formula    <IMAGE>  (aa)  Pharmaceutical compositions, preparations and use as a medicine are described.
Patent DE-69417235-D1 (DE)
Inventor: ALOUP JEAN-CLAUDE
IPC: A61K31/415
Filed: 1994-07-11
Granted: 1999-04-22
Abstract: Compounds of formula (I), wherein either R is C=R3, C(R4)R5 or CH-R6, R1 and R2 are hydrogen, halogen, alkyl, alkoxy, amino, acylamino, -NH-CO-NH-Ar, -N=CH-N(alk)alk', nitro, cyano, phenyl, imidazolyl or SO3H, R3 is oxygen, NOH, NO-alk-COOK or CH-R7, R4 is alkyl, -alk-Het or alk-Ar, R5 is alkyl, -alk-Het or -alk-Ar, or C(R4)R5 is cycloalkyl, R6 is hydroxy, alkyl, NR8R9, -alk-OH,-alk-NR8R9, -alk-Ar or -alk-Het, R7 is hydroxy, alkyl, phenyl, -alk-Ar, -alk-Het, NR10R11 or a heterocyclic ring, R8 and R9 are alkyl, or R8 is hydrogen and R9 is hydrogen or alkyl, -COR12, -CSR30 or -SO2R13, R10 and R11 are alkyl or cycloalkyl, R12 is alkyl, cycloalkyl, phenyl, -COO-alk, -CH2-COOX, -CH2-NH2, -NH-alk, -NH-Ar, -NH2 or -NH-Het, R13 is alkyl or phenyl, R30 is -NH-alk, -NH-Ar, -NH2 or -NH-Het; or R is a 2-imidazolylmethyl radical and each of R1 and R2 is a hydrogen atom. The compounds of formula (I) are  alpha -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, said receptor also being known as the quisqualate receptor. Furthermore, the compounds of formula (I) are non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, and especially NMDA receptor glycine modulation site ligands.
Patent DE-69419577-D1 (DE)
Inventor: KONDO AKIRA
IPC: C07K14/775
Filed: 1994-10-19
Granted: 1999-08-26
Abstract: Disclosed herein is an assay of a denatured lipoprotein, in which the denatured site of the denatured lipoprotein contained in a vital sample is exposed to the surface of its lipoprotein particle upon the reaction of an antibody, which recognizes the denatured lipoprotein, with the vital sample containing the denatured lipoprotein.
Patent DE-69419911-D1 (DE)
Inventor: FALK K
IPC: B01J32/00
Filed: 1994-05-11
Granted: 1999-09-09
Abstract: A gas-cleaning catalytic unit for use in cleaning exhaust gases from small internal combustion engines, comprises an open mesh knitted or woven fabric (10) produced from heat-resistant metal wire and shaped to a pack of predetermined form having a plurality of adjacent metal fabric layers, and a casing which surrounds the pack and forms gas throughflow passages. The unit is characterized in that at least half of the layers in the metal fabric pack are comprised of metal fabric (10) which is corrugated generally continuously in at least two directions along lines (14; 15) which define an angle ( beta ) therebetween; and in that the corrugated metal fabric (10) is so arranged in the pack that the apex of said angle will point in a direction transversely to the direction of the throughflow passages.
Patent DE-69423982-D1 (DE)
Inventor: MCMASTER A
IPC: C03B35/24
Filed: 1994-09-09
Granted: 2000-05-18
Abstract: Apparatus (10) for positioning a heated glass sheet G includes a longitudinally extending air flotation conveyor (12) for receiving and floating the heated glass sheet, a glass sheet vacuum mold (14) movably mounted above the air floatation conveyor for receiving the heated glass sheet, a glass sheet positioner (16) mounted relative to the mold for peripherally engaging and laterally and longitudinally positioning the glass sheet with respect to the mold and an array of lift jets (18) interspersed amongst the air flotation conveyor and located beneath the mold for lifting the glass sheet onto the vacuum mold through the application of lifting air on the bottom surface of the glass sheet. A glass sheet processing ring (26) transversely movable relative to the air flotation conveyor (12) subsequently receives the glass sheet from the mold (14). A method for positioning the heated glass sheet includes the steps of conveying the glass sheet on a cushion of air, peripherally engaging the floating glass sheet, locating the engaged floating glass sheet beneath a vacuum mold, applying jets of lifting air to lift the floating glass sheet upwardly to the vacuum mold, and applying vacuum to engage the positioned glass sheet on the vacuum mold.
Patent DE-69424738-D1 (DE)
Inventor: ANTENUCCI ROBERT N
IPC: A23L21/10
Filed: 1994-10-20
Granted: 2000-07-06
Abstract: A reduced calorie fruit spread comprising the gelled product of:     a. water;   b: fruit or fruit flavoring; c. one or more high intensity sweeteners selected from the group consisting of aspartame; saccharin; acesulfame-K; mixtures thereof; and mixtures of aspartame, saccharin, or acesulfame-K with sucralose;     d. low methoxy pectin or carrageenan;   e. carboxymethylcellulose;   f. guar gum; and g. locust bean gum. in
Patent DE-69426908-D1 (DE)
Inventor: DE NANTEUIL GUILLAUME
IPC: A61P9/10
Filed: 1994-06-08
Granted: 2001-04-26
Abstract: Compound of formula (I):    <IMAGE>  (I)  in which: R1 represents a hydroxyl, alkoxy or amino (unsubstituted or substituted) group, R2 represents an unsubstituted or substituted alkyl group, X1 represents -NH-, X2 represents -0-, R3 represents a hydrogen atom or an alkyl or phenyl group, R4 represents an alkyl group which is always substituted with one or more hydroxyl, benzyloxy, benzyloxycarbonylamino, amino, mono- or dialkylamino, acetoxy or 2,2-dimethyl-1,3-dioxolan-4-yl groups, such groups being identical or different, R5 represents a 3-indolylmethyl, naphthylmethyl, alkyl, phenyl or benzyl group, its isomers as well as its addition salts with a pharmaceutically acceptable acid or base, and medicinal products containing the same are useful as endothelin convertase inhibitor.
Patent DE-69511203-D1 (DE)
Inventor: ZINGARELLI ANGELO
IPC: B61F5/50
Filed: 1995-03-06
Granted: 1999-09-09
Abstract: A detecting system for rail vehicles having at least one sprung rigid structure (F), for instance a bogie frame (C), and two axles (A1, A2), comprising photosensor position-detecting means (L11, L12, L21, L22, LM) applied to the structure (F) and adapted to detect typical geometrical characteristics of the track (T1, T2) and the relative position between the axles and the rails when the vehicle is running along the track and to supply electrical signals which are indicative of such geometrical characteristics and such relative position, and displacement detecting means (V11, V12, V21, V22, X11, X12, X21, X22, R1, R2) also applied to the structure (F) and adapted to detect relative displacements between the structure (F) and the axles (A1, A2) and to supply electrical signals indicative of these displacements. Electronic acquisition and processing means of these electrical signals provide a monitoring related to the configuration of the track (T1, T2) and to the dynamic attitude of the structure (F) and of the two axles (A1, A2). <IMAGE>
Patent DE-69512118-D1 (DE)
Inventor: TOUGERON RAYMOND
IPC: F42B12/46
Filed: 1995-03-27
Granted: 1999-10-21
Abstract: The projectile, esp. a bullet, consists of a case (1) with an inner cavity (6) containing an active product (8) such as an irritant fluid, a powder or a dye, which is released on impact. It has a propellant element (5) and can have a recess shaped to form a braking surface lying perpendicular to the direction of the bullet's trajectory. The case can also have rupture lines so that it bursts more easily on impact to disperse the product inside. <IMAGE>
Patent DE-69518194-D1 (DE)
Inventor: BROADHURST MICHAEL JOHN
IPC: A61K31/454
Filed: 1995-04-12
Granted: 2000-09-07
Abstract: The invention provides hydroxamic acid derivatives of the general formula <CHEM> wherein R<1> represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R<2> represents a saturated 5- to 8-membered monocyclic or bridged N-heterocyclic ring which is attached via the N atom and which, when it is monocyclic, optionally contains NR<4>, O, S, SO or SO2 as a ring member and/or is optionally substituted on one or more C atoms by hydroxy, lower alkyl, lower alkoxy, oxo, ketalized oxo, amino, mono(lower alkyl)amino, di(lower alkyl)amino,carboxy, lower alkoxycarbonyl, hydroxy-methyl, lower alkoxymethyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or hydroxyimino; R<3> represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S, SO or SO2 as an additional ring member, (c) is substituted by oxo on one or both C atoms adjacent to the linking N atom and (d) is optionally benz-fused or optionally substituted on one or more other C atoms by lower alkyl or oxo and/or on any additional N atom(s) by lower alkyl or aryl; R<4> represents hydrogen, lower alkyl, aryl, aralkyl or a protecting group; m stands for 1 or 2 and n stands for 1-4, and pharmaceutically acceptable salts thereof, which are collagenase inhibitors useful in the control or prevention of degenerative joint diseases such as rheumatoid arthritis and osteoarthritis or in the treatment of invasive tumours, atherosclerosis or multiple sclerosis. They can be manufactured either by hydroxamidating a corresponding novel carboxylic acid or by deprotecting a corresponding novel benzyloxycarbamoyl compound.