baber/WOPTO huggingface dataset:
Patent NZ-509376-A (NZ)
Title: Indole or carbazole derivatives for the treatment of chronic lyphocytic leukemia
Inventor: NARDELLA FRANCIS A
IPC: A61K31/407
Filed: 1999-07-08
Abstract: The indole or carbazole derivatives of formula I are used in the manufacture of medicament for the treatment of chronic lymphocytic leukemia (CLL), B-cell lymphoma or lymphoma wherein: R1 is hydrogen, lower alkyl, lower alkeny, lower alkynyl, alkoxyloweralkyl, lower cycloalkyl, phenyl, benzyl and 2- thienyl; R2 and R3 are the same or different selected from hydrogen and lower alkyl; R4 and R5 are the same or different selected from hydrogen, lower alkyl, -NH2, -NHCHO, -NHCONH2, =NW, oxo, -OH and OCH3, wherein W is hydroxy, alkoxy, aryloxy, carboxyalkyloxy, arylamino or alkylsulfonylamino R6 is selected from hydrogen, lower alkyl, lower alkenyl, lower alkynyl, trifluromethyl, hydroxy, lower alkoxy, trifluroloweralkoxy, benzyloxy, araloxy, lower alkanoyloxy, acyl, amino, nitro, cyano, alkylimido, halo, mercapto, loweralkylthio, alkylsulfinyl, alkylsulfonyl, akylsulfonamido and sulfamoyl; R7 is selected hydrogen, lower alkyl and lower alkenyl; X is selected form carbon, oxy and thio; Y is selected from carbonyl, and formulas (a)-(c); R8, R9, R10, R11, R12 and R13 are hydrogen or lower alkyl and Z is selected form hydroxy, lower alkoxy, amino, lower alkylamino, di(lower)alkylamino and phenylamino; Or pharmaceutically acceptable salt thereof.
Patent NZ-513077-A (NZ)
Title: Methods for making proteins containing free cysteine residues
Inventor: DOHERTY DANIEL H
IPC: A61K47/48
Filed: 2000-01-14
Abstract: A method for obtaining a soluble protein, such as a growth hormone or erythropoietin, having at least one added free cysteine residue comprising the steps of: (a) obtaining an isolated host cell capable of expressing the soluble protein; (b) exposing the host cell to a cysteine blocking agent prior to step (c) wherein said cysteine blocking agent forms a stable, mixed disulfide with at least one cysteine residue in said soluble protein; and (c) isolating the soluble protein from the host cell, wherein said soluble protein contains at least on added free cysteine residue. The soluble proteins can be modified to increase their effectiveness by attaching a polyethylene glycol (PEG) to the free cysteine residue.
Patent NZ-520248-A (NZ)
Title: Method and apparatus for the weighing of sheets of wood material
Inventor: MANNIKKO ARI
IPC: B27N3/18
Filed: 2001-01-11
Abstract: Method and system for the weighing of sheets (6) of wood material on a sheet forming line, on which line the sheets are carried on a conveyor from a sheet forming apparatus and cooled down in a cooling turn gear comprising a cooling wheel (3) provided with radial supporters (5). The sheets (6) are weighed using a weighing system (8) which has been fitted in the cooling turn gear and which weights the sheets (6) when they are turned to an upright position or at least to a nearly upright position. The method and system makes it possible to leave out the conveyor weight meter from the press line, thus allowing the press line to be made shorter. The weighing accuracy is substantially better than in a conventional conveyor weight meter solution because only the sheet itself is weighed instead of weighing the relatively heavy conveyor together with the light sheets on it.
Patent NZ-520606-A (NZ)
Title: Pyrrolopyridazine derivatives useful for preventing or treating ulcerative diseases
Inventor: IWABUCHI HARUO
IPC: A61K31/5025
Filed: 2001-02-06
Abstract: A pyrrolopyridazine derivative or a pharmaceutically acceptable salt thereof has the formula (I) wherein: R1 is alkenyl, halogen alkenyl, optionally substituted cycloalkyl or optionally substituted cycloalkylalkyl; R2 is alkyl; R3 is hydroxymethyl, aliphatic acyloxymethyl, optionally substituted arylcarbonyloxymethyl, alkoxycarbonyloxymethyl, formyl, carboxyl, alkoxycarbonyl or optionally substituted aryloxycarbonyl; R4 is optionally substituted aryl and A is an imino, oxygen or sulphur atom.
Patent NZ-521537-A (NZ)
Title: Machine for blow-moulding containers made of plastic material, with acuating devices of the electric type
Inventor: GIACOBBE FERRUCCIO
IPC: B29L22/00
Filed: 2002-09-23
Abstract: A machine for moulding containers made of plastic material, comprising an assembly for extruding tubes of plastic material, a blowing assembly, a mould for containing containers, formed by two half-moulds movable upon actuation of associated first means, in a longitudinal direction and symmetrical with respect to a fixed axis perpendicular to the longitudinal direction, the assembly formed by the mould and associated first actuating means being movable, upon actuation of second actuating means, in a transverse direction from a position corresponding to the extrusion assembly to a position corresponding to the blowing assembly and vice versa, wherein the first means for actuation of the half-moulds in the longitudinal direction are of the electric type and means for symmetrically adjusting the distance of the two half-moulds from the fixed axis are provided.
Patent NZ-524645-A (NZ)
Title: A method for the preparation of soil samples
Inventor: RAJENDRAM GORDON SHANTHAKUMAR
IPC: G01N21/35
Filed: 2003-03-07
Abstract: A method for determining the presence, concentration and/or volume of at least one component in a soil sample, including steps of: (a) adding at least one aqueous solution to a soil sample; (b) adding at least one complexing agent to a mixture from step (a); analyzing the result of step (b) via NIR or UV/Vis spectrometry; characterized in that step (a) is completed within 10 minutes and; further characterised in that steps (a) and (b) prepare the sample in a manner that is suitable for NIR or UV/Vis spectrometry.
Patent NZ-525792-A (NZ)
Title: Coil and coil-head formation dies for coils with non-conventional terminal convolutions
Inventor: DEMOSS LARRY
IPC: F16F1/02
Filed: 2001-11-13
Abstract: Machinery for automated manufacture of innerspring assemblies (1) for mattresses and flexible support structures includes coil formation devices (201, 202) configured to produce generally helical spring coils (2) having a terminal convolution (26) which extends beyond an end of the coil and a conveyor system (301, 302) having a plurality of flights (308) connected to a chain (315) and driven by an index driver (320) which delivers formed coils to an innerspring assembler (500). A coil forming block (208) on a coiler machine has a cavity (218) in which a terminal convolution of the coil is formed, and from which the coil is cut by a cutter (212) which extends into the cavity. Coil head formation dies (2000) at coil head forming stations (230, 240) of the coil forming machine also have a cavity (2010) for receiving a terminal convolution of a coil, and flanges (2007, 2008) which surround the cavity and provide a punch set for punches (232) which form a coil head proximate to the terminal convolution in the die.
Patent NZ-526912-A (NZ)
Title: Inhibitors of cruzipain and other cysteine proteases
Inventor: QUIBELL MARTIN
IPC: C07D307/935
Filed: 2002-01-17
Abstract: Disclosed are compounds of formula (I), wherein: R1 is H, alkyl, cycloalkyl, Ar or Aralkyl, wherein the Ar is optionally substituted, Z is O or S, Y is CR5R6-CO, wherein R5 and R6 are H, alkyl, cycloalkyl, Ar or Aralkyl, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases affected by inhibiting a cysteine protease.
Patent NZ-527610-A (NZ)
Title: Dive float
Inventor: GRUNDY KANE GORDON
IPC: B63C11/46
Filed: 2003-08-18
Abstract: A diver flotation unit (dive float) (2) comprising a PVC or plastic hull filled with foam to enable buoyancy. The device has a PVC bag (4) with fittings for closure (6) attached for stowage of diver's gear or catch. The device has a bungee cord or elasticised cording (3) attached across bow, stern and diagonally across mid-section for the stowage of large and bulky items. The device has D ring or metal ring attachments (7) to enable the attachment of anchoring lines to allow the device to be towed. The device has webbing strap handles (5) attached along the sides and across the rear.
Patent NZ-528968-A (NZ)
Title: Water heating having self-powered low NOx burner/fuel-air delivery system
Inventor: TRANT TROY E
IPC: F24H1/20
Filed: 2003-10-17
Abstract: Fuel fired heating apparatus having a combustion chamber with a fuel burner disposed therein and a fuel-air delivery system for delivering fuel and combustion air to the fuel burner for combustion to form combustion gases. The fuel-air delivery system including a fuel supply structure operative to discharge a quantity of fuel received from a source thereof, a first flow path for receiving the discharged fuel and a first quantity of combustion air and flowing the received fuel and air to the burner. A thermo electric generator is positioned to be heated by said burner during firing thereof, a second flow path through which a second quantity of combustion air may be delivered to said burner and a fan structure operable by said thermoelectric generator to deliver at least one of said first and second quantities of combustion air to said burner. The apparatus is operable even if either or both of said thermoelectric generator and fan structure fail to function.
Patent NZ-529199-A (NZ)
Title: Moulding materials having a fibrous layer with a resinous material
Inventor: CORDEN THOMAS
IPC: B29C70/54
Filed: 2002-04-23
Abstract: disclosed herein is a moulding material (10) comprising a fibrous layer (12) carrying resinous material (14) to have at least one area (16a, 16b, 16c and 16d) of relatively high resin content and at least one other area (18a, 18b and 18c) of relatively low resin content (18a, 18b and 18c) defined on a surface (20) of the fibrous layer (12) such that upon curing or partial curing resin from the said relatively high resin content area(s) (16a, 16b, 16c and 16d) moves over the relatively low resin content area(s) (18a, 18b and 18c) to provide a substantially even distribution of resin between the areas, wherein one or more airways are provided for removal of air during processing of the material.
Patent NZ-529265-A (NZ)
Title: Smallpox vaccine
Inventor: WELTZIN RICHARD A
IPC: A61K39/285
Filed: 2002-04-23
Abstract: Disclosed is a clonal strain of acceptably attenuated vaccinia virus. It is isolated from cultured cells in which the New York City Board of Health vaccinia virus strain, ACAM 1000 (ATCC Deposit No. PTA-332 I), or a progeny thereof (æthe strainsÆ) has been cultured. The vaccinia virus is described to be able to induce a protective or therapeutic immune response against variola virus (the causative agent of smallpox) in a human. A method of obtaining a colonal strain of attenuated vaccinia virus for use as a vaccine is also described. The method comprises: (i) propagating the strains, or a progeny thereof in a cell culture system, and (ii) isolating from the cell culture system a clonal strain of vaccinia virus that has substantially the same virulence, immunogenicity, growth characteristics in culture, or restriction endonucleases digestion pattern as the strains. The virulence is determined by a rabbit skin test, or by a sucking mouse neurovirulence test.
Patent NZ-530963-A (NZ)
Title: Taxol enhancer compounds
Inventor: KOYA KEIZO
IPC: A61P35/00
Filed: 2002-07-10
Abstract: Disclosed is a compound represented by the structural formula (I); Y is a covalent bond, a phenylene group or a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, taken together with both >C=Z groups to which it is bonded, is a substituted or unsubstituted aromatic group. Preferably, Y is a covalent bond or -C(R7R8)-. R1 and R2 are independently an aryl group or a substituted aryl group, R3 and R4 are independently -H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group. R5 and R6 are independently -H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group. R7 and R8 are each independently -H, an aliphatic or substituted aliphatic group, or R7 is -H and R8 is a substituted or unsubstituted aryl group, or, R7 and R8 taken together are a C2-C6 substituted or unsubstituted alkylene group. Z is =O or =S. Also disclosed is the use of a compound of the structural formula (I) in the preparation of pharmaceutical compositions for the purpose of treating a subject with cancer by administering to the subject a compound of structural formula (I) in combination with taxol or an analog of taxol.
Patent NZ-531595-A (NZ)
Title: Crinkling device
Inventor: SUOLAHTI YRJO
IPC: B65B11/04
Filed: 2004-03-08
Abstract: The invention relates to a crinkling device comprising a slide rod to which a second crinkling element is fastened. The slide rod is guided in a frame so as to be movable in a substantially vertical direction between a lower position in which the second crinkling element is out of contact with the lower edge of a foil web and an upper position in which the second crinkling element deflects the lower edge of the foil web upwards so as to crinkle it. The slide rod returns to the lower position when not exposed to an upward force. The device further comprises coupling means for providing a releasable coupling between the slide rod and the first drive element portion when the drive element is running in a first direction to move the second crinkling element to the upper position. Second coupling means are provided to provide a coupling between the slide rod and a second drive element portion when the drive element is running in a second direction to move the second crinkling element to the upper position. By driving the drive element in the second running direction, the foil web can be crinkled optionally either from the upper edge by a first crinkling element without crinkling the lower edge or from the upper edge and the lower edge simultaneously.
Patent NZ-532550-A (NZ)
Title: Compositions incorporating (-)-hydroxycitric acid, chromium, and gymnemic acid, and related methods for promoting healthy body weight and improving related health factors
Inventor: BAGCHI DEBASIS
IPC: A61K33/24
Filed: 2002-12-20
Abstract: Use of a combination of (-)hydroxycitric acid bound to potassium and calcium, chromium bound to naicin and gymnemic acid, to promote healthy body weight and improve physiological factors.
Patent NZ-536586-A (NZ)
Title: Dynamometer adapter for motorcycles
Inventor: ASKEY HOWARD WAYNE
Filed: 2004-11-16
Abstract: An adjustable adapter that allows motorcycles of a variety of output heights and drive types to be connected to dynamometers of various input heights is disclosed. The adapter includes an input axle to be fixed to a motorcycle in place of the rear wheel and an input sprocket 5 mounted on the input axle to engage a drive element 4 connected to the output 1 of the motorcycle engine. The adapter includes an output shaft 14 adapted to connect to a dynamometer and a drive chain 10 to transmit the power from the input sprocket to the output shaft. The input axle is connected to the output shaft by one or more linkages 24, each linkage being pivotable in order to adjust the relative positions of the input axle and output shaft.
Patent NZ-540098-A (NZ)
Title: Use of CPG oligonucleotides in the treatment of hepatitis C virus infection
Inventor: AHLUWALIA NAVNEET K
IPC: A61K31/7088
Filed: 2003-10-29
Abstract: Disclosed is the use of a CpG immunostimulatory nucleic acid in the manufacture of a medicament for the treatment of a chronic hepatitis C viral (HCV) infection, where the patient was previously unsuccessfully treated with a non-CpG therapy. In some instances, the subjects are those that are non-responsive to non-CpG therapy. Further disclosed are methods for identifying CpG immunostimulatory nucleic acids for the ability to stimulate an immune response in the treatment of a chronic HCV infection. Preferably, the CpG immunostimulatory nucleic acids are C class having a semi-soft backbone.
Patent NZ-541219-A (NZ)
Title: Thiophene carboxamides as inhibitors of the enzyme IKK-2
Inventor: MORLEY ANDREW DAVID
IPC: C07D409/12
Filed: 2004-01-13
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. The compounds are IKK-2 inhibitors useful in the treatment of inflammatory diseases and cancer.
Patent NZ-541624-A (NZ)
Title: Flag with a non-linear edge formed by cord or boltrope of increased thickness, and flagpole for such flag
Inventor: HUME PETER JOHN
Filed: 2005-08-03
Abstract: A flag or banner has a curved edge 3 formed by a cord or boltrope of increased thickness compared to the adjacent flag sheet. A flagpole 4 is also disclosed with a curved guide track having a longitudinal open hollow which opens at a slot narrower than the width of the hollow.
Patent NZ-543956-A (NZ)
Title: Protective footwear
Inventor: ALLENDER RUSSELL DONALD
Filed: 2005-12-02
Abstract: A fire-resistant boot having a sole and an upper attached to the sole, the upper including an opening enabling the boot to be placed on the wearer's foot. The upper includes fire resistant elastic material which enables the opening of the boot to be expanded from a relaxed condition to a stretched condition to facilitate insertion of the wearer's foot through the opening. The upper also includes fire-resistant covering material which provides at least partial cover of the elastic material whilst the boot is in a relaxed condition, thereby protecting the covered portion of the elastic material from heat external to the boot.
Patent NZ-550080-A (NZ)
Title: Method of and system for generating an authorized domain
Inventor: LENOIR PETRUS JOHANNES
IPC: G06F21/10
Filed: 2005-03-15
Abstract: A method of generating an Authorized Domain is disclosed. The method comprises the steps of: (a) selecting a domain identifier uniquely identifying the Authorized Domain, (b) binding at least one user to the domain identifier by obtaining or generating a Domain Users List comprising the domain identifier and a unique identifier for a user, thereby defining that the user is bound to the Authorized Domain, (c) binding at least one device to at least one user by obtaining or generating a Device Owner List comprising a unique identifier for a user and a unique identifier for each device belonging to the user, thereby defining that the at least one device is/are bound to the user, or binding at least one device to at least one user by obtaining or generating a Device Owner List for each device to be bound, where the Device Owner List comprises a unique identifier for a user and a unique identifier for a device belonging to the user thereby defining that the device is bound to the user, (d) obtaining a number of devices and a number of users that are authorized to access a content item of the Authorized Domain, and (e) controlling access, by a given device being operated by a given user, to a given content item, by checking whether a user, the given content item is linked to, and a user, the given device is linked to, belongs to the same Authorized Domain, and allowing access for the given user and/or other users via the given device to the content item if so, and/or checking if the given content item is linked to a user belonging to the same Authorized Domain as the given user, and allowing access for the given user via the given device and/or other devices to the content item if so.
Patent NZ-552475-A (NZ)
Title: Phonetic alphabet and system for use
Inventor: GRAHAM DAVID ALBERT
IPC: G06K9/00
Filed: 2007-01-08
Abstract: Word processing equipment having a keyboard bearing a phonetic alphabet is disclosed. The phonetic alphabet comprises a set of characters with each character representing a single sound used in speech, including single characters equivalent to digraphs in Standard English. Each digraph comprises a single composite character composed of strokes characteristic of both of two letters of the digraph. In use the composite character can be recognised as relating to the digraph and the sound it represents. The alphabet further includes the use of different vowel characters to represent different sounds attributed to a vowel in Standard English. Each the vowel character includes strokes characteristic of the vowel. In use the vowel character can be recognised as relating to the vowel and a sound it represents and the same sound is always represented by the same character. Software includes a means to present an output which can be represented in the phonetic alphabet as described above and the phonetic alphabet itself is disclosed.
Patent NZ-552982-A (NZ)
Title: A method to increase pathogen resistance in plants
Inventor: DE BOER ANNE DOUWE
IPC: A01H5/00
Filed: 2005-07-25
Abstract: Discloses a method for enhancing pathogen resistance in plants by providing these plants with a gene construct comprising a DNA sequence coding for a receptor, wherein said receptor is a Receptor Kinase-like SERK (RKS) receptor.
Patent NZ-554260-A (NZ)
Title: Selenomethionine andor selenocysteine administration to non-human animals to increase selenium content in protein sources
Inventor: KNOWLES SCOTT OLIVER
IPC: A23K1/16
Filed: 2007-09-30
Abstract: Disclosed is a method of increasing selenium content in protein sources from an animal, such as milk or meat, by orally administering a tablet containing selenocysteine, selenomethionine, or combinations thereof. Also disclosed is a tablet containing selenomethionine, for oral administration, to increase selenium content of protein sources such as milk and meat from that animal, wherein the tablet releases selenomethionine over at least one month.
Patent NZ-564924-A (NZ)
Title: Electronic lock actuator with helical drive member engaging with a spring to lock and unlock the lock
Inventor: WALSH JOHN
IPC: E05B47/06
Filed: 2006-07-07
Abstract: An electronic lock is disclosed. The lock has a lock member (12) linearly displaceable between a locked position and an unlocked position. A motor (14) having a shaft (22) rotatable about a central axis (24) is either coupled with or integrally formed with a drive member (28). A coupler spring (16) is disposed about the axis and has a first end (16a) coupled with the lock member (12). A second, opposing end (16b) of the coupler spring is threadably engaged to the drive member (28) by a helical drive surface, provided by a second a helical spring (18). The helical spring (18) has a first end threadably engaged with the coupler spring (16) and a second end connected with the drive member (28). Rotation of the motor shaft (22) displaces the coupler spring (16) generally linearly along the axis (24) to move the lock member (12) between the locked and unlocked positions.
Patent NZ-567594-A (NZ)
Title: Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myeloproliferative diseases
Inventor: ZELDIS JEROME B
IPC: A61K31/724
Filed: 2003-04-13
Abstract: Disclosed is a use of an immunomodulatory compound of formula (II), wherein one of X and Y is C=O, the other of X and Y is C=O or CH2, and R1, R2 and n are as defined in the specification; or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent, in the preparation of a composition for treating or preventing a myeloproliferative disease in a patient. Particular second active agents are capable of suppressing the overproduction of hematopoietic stem cells or ameliorating one or more of the symptoms of a myeloproliferative disease. Pharmaceutical compositions comprising the above immunomodulatory compound and the second active agents are also disclosed, wherein the immunomodulatory compound and the second active agent are present in the composition in complementary amounts or synergistically effective amounts for the treatment, prevention or management of a myeloproliferative disease. (62) Divided Out of 540382