baber/WOPTO huggingface dataset:
Patent SG-11201903230Q-A (SG)
Title: TCRa HOMING ENDONUCLEASE VARIANTS
Inventor: JARJOUR JORDAN
IPC: A61K35/12
Filed: 2017-10-11
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101111 0 DOI HIM 011101 0 0111111111111111H1111111110111111111 Organization 0 International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2018/071565 Al 19 April 2018 (19.04.2018) WIP0 1 PCT (51) International Patent Classification: EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (21) A61K 35/12 (2015.01) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, International Application Number: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, PCT/US2017/056178 KM, ML, MR, NE, SN, TD, TG). (22) International Filing Date: Declarations under Rule 4.17: 11 October 2017 (11.10.2017) — as to applicant's entitlement to apply for and be granted a (25) Filing Language: English patent (Rule 4.17(0 — as to the applicant's entitlement to claim the priority of the (26) Publication Language: English earlier application (Rule 4.17(iii)) (30) Priority Data: Published: 62/406,689 11 October 2016 (11.10.2016) US — with international search report (Art. 21(3)) 62/414,266 28 October 2016 (28.10.2016) US — with sequence listing part of description (Rule 5.2(a)) (71) Applicant: BLUEBIRD BIO, INC. [US/US]; 60 Binney Street, Cambridge, Massachusetts 02142 (US). (72) Inventors: JARJOUR, Jordan; 11014 37th Ave SW, Seat- tle, Washington 98146 (US). POGSON, Mark; 3122 SE 16th St., North Bend, Washington 98045 (US). (74) Agent: MASHRUWALA, Mary Anne et al.; Cooley LLP, 1299 Pennsylvania Avenue, NW, Suite 700, Washington, District of Columbia 20004 (US). — = Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = _ (81) = _ = = Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (84) = _ _ = = = = Title: TCRa HOMING ENDONUCLEASE VARIANTS — (54) = Figure 1 fr — ,-, kin kin n 11 n1fl n9n 8 n7 n6 n5 n 4 n3 n2 1 13 1 p2 p3 p4 p5 p 6 p7 p8 p9 p10 p11 ,—, IN TCRa TGTCTGCCTATTCACCGATTTT 0 --.... KAT2 B IGTATSCCTATTCTACAAGAAA 1-1 0 ei (57) 0 : The present disclosure provides improved genome editing compositions and methods for editing a TCRa gene.
Patent HU-202935-B (HU)
Title: Process for producing sliding surface of lead-tin-polytetrafluoro-ethylene with galvanic method
Inventor: SZAKAL JOZSEF
IPC: C25D5/00
Filed: 1989-01-04
Abstract: 15-180g/l lead carbonate is added to a bath of borofluoric acid, together with a tin electrode and the electrolysis is carried out at 1-4A/1. After dissoln. glue is added to the bath, electrolysis continues with lead-tin anodes till the deposit on the cathode is less than 18% of the final thickness, then the following is added (g/l): 0.025-0.2 perfluor-octyl sulphonic acid, 1.25-40 ethylene-diamine-tetraacetate, 0.025-4 perfluoroethylcyclohexyl-sulp honic acid, 12-300 polytetra-fluoroethylene of 0.5-70 micron grain size. The coated item is immersed in this electrolyte, rinsed, and dried
Patent AT-394433-B (AT)
Title: Waste-gas header
IPC: F23J11/00
Filed: 1983-01-27
Granted: 1992-03-25
Abstract: Waste-gas header 1 for a heating system consisting of a plurality of boilers, with a housing 2 which has a connecting orifice 5 for the boilers and a common outlet orifice 10 for connection to a chimney leading further on, the housing of the waste-gas header having either a polygonal cross-sectional shape or a circular or oval cross section. At all events, the connecting orifices 5, 5',. 5", 5"', etc. for the boilers 8 are arranged, in each case in varying size and at varying intervals 6, 6', 6", 6"', on the longitudinal casing sides 3. <IMAGE>
Patent AT-406982-B (AT)
IPC: E06B9/52
Filed: 1997-04-14
Granted: 2000-11-27
Abstract: A dustproofing arrangement for windows and doors 1 has a dustproofing means 7 for covering the free window or door opening, the windows or doors having a sash or leaf 3, which is fastened such that it can be rotated or tilted on a case frame 2, and a window mechanism 4 for optionally pivoting open the sash 3 about a vertical axis of rotation D or a horizontal tilting axis K. In order to achieve effective dustproofing just in the tilted position of the sash or leaf (continuous ventilation), there is arranged between the case frame 2 and sash or leaf 3 a hollow frame 6 which comprises two shell parts 61 and 62, which are articulated on one another such that they can be pivoted about an articulation S running in the region of the bottom frame leg 63, and accommodates a collapsible dustproofing means 7 which is mounted between the connection brackets 71, which can be pivoted in relation to one another about the hinge axis S, one connection bracket 71 being positioned right against one shell part 61, and the other connection bracket 72 being positioned right up against the other shell part 62, and only one of the shell parts 62 being connected firmly to the associated sash or leaf 3. <IMAGE>
Patent HU-199567-B (HU)
Title: Process for melting metals in inductive arc-furnace
Inventor: MALINOVSKY VLADIMIR S
IPC: H05B6/24
Filed: 1986-05-30
Abstract: A method for melting a metal in an induction plasma furnace consists in melting the metal (2) by means of the plasma arc (8) and the magnetic field of the inductor (4) and in effecting an interaction between the plasma arc (8) and the magnetic field of the inductor (4), this interaction being accompanied by fluctuations in the energy parameters of the plasma arc (8) and by the appearance of an acoustic pressure. Then, the values of the energy parameters of the plasma arc (8) are analised and compared with the preset values of the energy parameters of the plasma arc (8). At the same time, the acoustic pressure level is measured at each moment of its appearance during the interaction of the plasma arc (8) with the magnetic field of the inductor (4) while the plasma arc (8) is penetrating into the melted metal (2), and the intensity of the magnetic field of the inductor (4) is reduced until the acoustic pressure is eliminated.
Patent HU-184511-B (HU)
Inventor: KALDOR ISTVAN
IPC: A01K93/00
Filed: 1982-03-04
Abstract: A találmány szerinti horgászúszó lényege, hogy a műanyagból készült vízmentes zárótesttel rendelkező úszó-; testhez oldható kötéssel fényáteresztő tulajdonságú külső fallal rendelkező kapszula, illetve zárókupak csatlakozik. A felerősített zárókupak alatti térrészben ugyancsak tényáteresztő tulajdonságú patron helyezhető el. A rugalmas tulajdonságú külső fallal rendelkező kapszula és' patron belsejében eltávolítható választó elemmel vagy elemekkel egymástól elválasztva egy önmagában ismert kemilumineszkáló kompozíció egyes komponensei és/vagy egymással inért komponenseinek keverékei helyezkednek el, oly módon, hogy a választó elem vagy elemek eltávolításakor keletkező kemilumineszkáló kompozíció legalább részben a külső fal fényáteresztő része mögött van. A választó elemek kívánságra eltávolíthatók, a kompozícióban lezajló kémiai reakció során fény sugárzódik ki, így sötétben való horgászáskor a horgászúszó 2-12 órán keresztül 15—20 méterről is jól láthatóvá válik.  ábra   2. ábra -1-
Patent HU-188007-B (HU)
Title: Process for producing 1-onochloro-ethyl-carbamoyl-chloride
Inventor: KOENIG KARL-HEINZ
IPC: B01J19/12
Filed: 1981-04-03
Abstract: A process for the preparation of 1-monochloroethylcarbamyl chloride by chlorinating ethyl isocyanate or ethylcarbamyl chloride. The 1-chloroethylcarbamyl chloride obtainable according to the invention is an important starting material for the preparation of 1-chloroethyl isocyanate and vinyl isocyanate and accordingly a valuable starting material for the preparation of pest control agents, dyes, drugs, textile waterproofing agents, detergents, plastics, bleaching agents and adhesives, since the said isocyanates contain, in addition to a reactive isocyanate group, an activated double bond or an activated  alpha -carbon atom.
Patent HU-189250-B (HU)
Title: Method for increasing the solidity and impermeability of soils
Inventor: BABOS LASZLO
IPC: E02D3/00
Filed: 1983-03-23
Abstract: Treatment uses water glass and polymer based gel forming system. - System consists of a mixt. of conc. or water-diluted water glass, the dilution of which is less than 1:5 wt.% by wt. opt. contg. additives and 0.1-20.0 wt%, pref. 1-5 wt.% based on water glass of a soln. in a low molecular wt. ester solvent or of an aq. dispersion or suspension of a polymer or of polymers contg. ester linkages which hydrolyse is less than 8 hours, pref. in 0.25-2.0 hrs to water soluble polymers. After hydrolysis the mixt. is transformed into a hydrogel by treatment with crosslinking agents dissolved in ester type solvents and/or under the action of metal salts present in the soil or in the groundwater. - Useful soluble polymers are poly-vinyl-acetate, poly-vinyl-acetate-vinyl-ester or poly-vinyl-acetate-acrylic-acid copolymers with low, medium or high molecular wt. the polymer concn. in the ester solvent is 1-30 wt.%, pref. 5-20 wt.%. The ester may be a satd. or unsatd. mono-, di- or tri-ester or a mixt. of these.
Patent RS-49988-B (RS)
Inventor: HACKER ERWIN
IPC: A01N47/06
Filed: 1999-08-10
Abstract: Primena kombinacija herbicida za uništavanje korova u kulturanv kukuruza, naznačena time, što odredjene kombinaci.ie herbicida imaju aktivan sastav (A) herbicida sa širokim delovanjem iz grupe jedinj enja, koja se sastoji od (A1) jedinjenja prema formuli (A1) gde Z označava ostatak formule -OH ili peptidni ostatak formule -NHCH(CH3)CONHCH(CH3)COOH ili -NHCH(CH3)CONHCH[CH2CH(CH3)2]COOH i njegove estre i soli i ostale fosfinotricin derivate, (A2) jedinjenja prema formuli (A2) i njihove estre i soli i (B) jednog ili više herbicida iz grupe jedinjenja koja se sastoji od (B 1) herbicida iz grupe cianazin, alahlor,benoksakor, rimsulfuron, f1utiamid, sulkotrion, mesotrion i pentoksamid, (B2) herbicida iz grupe metosulam, metribuzin, hloransulam, linuron, florasulam i izoksahlortol, i (B3) herbicidi iz grupe tifensulfuron, karfentrazon, tritosulfuron (Lab271272), MCPA, halosulfuron, diflufenzopir i sulfosulfuron i kultura kukuruza koje su tolerantne na herbkide (A) i (B) sadržane u kombinacijama, uz eventualno prisustvo sredsta'ra protiv opasnosti. Prijava ima još 8 zahteva.
Patent ZA-84449-B (ZA)
Title: Liquid cleansing compositions
Inventor: HARMER JANE
IPC: C11D17/00
Filed: 1984-01-20
Abstract: Hair or body shampoo compositions having an upper aqueous layer and a lower aqueous layer which are temporarily dispersible one in the other upon agitation of the composition and wherein each layer is miscible with water in substantially all proportions. The upper layer has dissolved therein at least one detergent. The lower layer contains sodium hexametaphosphate dissolved therein. The compositions have cleansing properties and impart a conditioning effect.
Patent AT-399203-B (AT)
Title: Apparatus for driving tunnels and galleries
IPC: E21D9/08
Filed: 1992-05-29
Granted: 1995-04-25
Abstract: In an apparatus for driving tunnels and galleries, having a tunnelling machine 1 with a tunnelling shield 3 and a non-rigid shield tail 4 to 7, within the protection of which a lining for the tunnel or gallery can be attached, preferably by the prefabricated tubbing method, at least the lining end of the shield tail 4 to 7 or the tunnelling shield of the tunnelling machine and the shield tail are each constructed from two or more annular courses 5, 6, 7 or annular segments which can be adjusted via drive devices and adjustment devices to different outer ring diameters and/or different lengths of a transition zone 8, defined by them, between the excavation diameter and the smaller lining diameter. <IMAGE>
Patent AT-393754-B (AT)
Title: Musical instrument
IPC: G10D13/063
Filed: 1990-06-22
Granted: 1991-12-10
Abstract: In previously used stands, the mounting for cymbals and similar musical instruments is fixed and immovable. If it is desired to produce a phasing sound, this can be achieved only with an electronic effects unit. The instrument 6 according to the invention is fastened to a support 4, 10 mounted rotatably on the stand 1, 2, 2". The rotary mounting makes it possible for the instrument to rotate and defines the intensity of the phasing according to the playing strength. By means of a displaceable counterweight 11, the position of the centre of gravity of the rotating parts, instrument 6, support 4, 10 and mounting 5, can be adjusted, so that different instruments can be used. Brake arrangements are provided in order to stop the rotation of the instrument. In the practical, musical area of application, the rotary mounting for the instruments makes it possible to achieve not only a mechanically produced phasing sound but also an optical effect. <IMAGE>
Patent AT-399319-B (AT)
Title: Laying of electrical wiring in a motor vehicle to a vehicle door
Inventor: SCHOENEGGER-FOESLEITNER ERICH
IPC: B60R16/02
Filed: 1993-07-22
Granted: 1995-04-25
Abstract: The invention relates to the laying of electrical wiring 8 through an opening 9 in a frame 3 on a motor-vehicle body to a vehicle door 2 hinged to the frame 3, and to electric consumers, such as outside-mirror heating and/or adjusting devices, door loudspeakers, electric motors for window opening, and central locking, which are arranged on or in said vehicle door. In order to ensure that the electrical wiring is routed in a safe manner in the transition region between the body and door and in order to avoid the wiring breaking because of repeated opening and shutting of the door, the invention makes provision for the electrical wiring 8 to be laid through a sickle-shaped cable-guiding shaft 12. Said shaft is attached to the inside door panel 6 by a first, in particular straight section 12/1. With its second section 12/2 which is curved in an arcuate manner, the cable-guiding shaft 12 spans the clearance between the door 2 and frame 3 and protrudes through the opening 9 in the frame 3 into the body clearance 4 situated behind it. The cable-guiding shaft 12 ends here at an imaginary line passing through the swivel pin 5 of the door hinge. This ensures that the electrical wiring which is laid inside the cable-guiding shaft virtually does not change its position even when the door is opened, and therefore is also not subjected to any kind of mechanical load in the region in question. <IMAGE>
Patent AT-401243-B (AT)
Title: Apparatus for producing spacer frames for panes of insulating glass from hollow sectional strips
IPC: B21D53/74
Filed: 1992-07-16
Granted: 1996-07-25
Abstract: In an apparatus for bending hollow sectional strips into spacer frames for panes of insulating glass which has a sloping supporting wall 1, at the bottom edge 8 of which at least one bending head 2 is provided, a conveyor track 20 for feeding in hollow sectional strips to be bent into spacer frames and an apparatus 40 for transferring hollow sectional strips from the conveyor track 20 into supports 7 in the region of the lower edge 8 of the supporting wall 1 are provided behind the supporting wall 1. As a result, the space behind the supporting wall 1 is used and the front side of the apparatus remains free so that it can be entered without danger by an operator and deposition space is saved. <IMAGE>
Patent AT-399060-B (AT)
Title: Method of controlling a pump
IPC: F24D19/10
Filed: 1992-12-07
Granted: 1995-03-27
Abstract: Arrangement and control of a pumping system 4 of a circulated-water heating system, having a heat source 1 and heat loads comprising radiators 5. In order to save energy, provision is made for the pump system 4 to have two hydraulically parallel 41, 42 pumps or pumps 43, 44 connected in series and having different outputs, the said pumps being controlled on the basis of the heat requirements. <IMAGE>
Patent CH-612556-B (CH)
Inventor: TAKAI ISAO
IPC: D02G1/08
Filed: 1976-06-24
Abstract: A method and an apparatus for producing crimped filament yarns, said apparatus comprising at least one first twister member and at least one second twister member, each of said twister members having a work surface made of a synthetic rubber having a relatively small friction coefficient therebetween. These twister members are arranged so that their work surfaces cross each other at a selectable angle in contact relationship to provide at least one crossing zone for nipping therebetween at least one thermoplastic filament yarn which is fed to twist this filament yarn between the contacting work surfaces successively and at the same time to urge this filament to discharge from this crossing zone successively as the twister members are driven. This method and apparatus allow filament yarns to be imparted desired false-twisting effect, practically without being damaged and without causing uneven twists, at a high operation rate of 800 - 1000 meters per minute.
Patent DK-163410-B (DK)
Inventor: MOENCH EBERHARD
IPC: A01K13/00
Filed: 1985-03-22
Abstract: 1. A dip instrument for udder hygiene in which a teat is dipped into a liquid hygiene preparation, comprising a cup (3) to be supplied with liquid hygiene preparation (15) from a reservoir (1), the reservoir (1) being integrally formed on the side of the cup (3) and having a product outlet (8) to the cup, characterized in that the cup (3) is connected to the product outlet of the reservoir (1) by a tube section (4) integrally formed on the side of the cup while the reservoir is connected to the tube section (4) by an air-tight coupling (6), in that the longitudinal axes of the tube section (4) and cup (3) are substantially perpendicular to one another, in that a funnel (5) is inserted into the cup opening in air-tight manner and comprises at least one vent (1) at substantially the centre of the funnel and at least one opening (10) in or at the base of the funnel, in that the funnel (5) and, more particularly, its opening is designed to fit over any teat, in that the uppermost part of the product outlet (8) in the working position is level with or above the vents (11) in the funnel (5).
Patent DK-154922-B (DK)
Inventor: LINK WERNER
IPC: A47C3/30
Filed: 1983-10-03
Abstract: In a gas pressure spring for a chair, a locking device is provided, which includes a safety sleeve formed of two semi-circular halves which are clamped on an outer tube of the gas pressure spring by clamping bolts. The outer tube is formed with an end portion of a reduced diameter and a transition zone. The two halves of the safety sleeve are formed each with an inner collar matching the transition zone of the outer tube. One of the halves is formed with a through opening for passing a height-adjusting lever towards the outer tube.
Patent DK-164159-B (DK)
Inventor: FREYNE EDDY JEAN EDGARD
IPC: C07D409/06
Filed: 1986-11-03
Abstract: Novel [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters of formula whereinR is hydrogen, C<sub>1-10</sub>alkyl, trifluoromethyl, Ar or Ar(C<sub>1-10</sub>alkyl), said Ar being phenyl, naphthalenyl, both being optionally substituted, pyridinyl, pyrimidinyl, furanyl or thienyl; andR¹ is hydrogen or C<sub>1-6</sub> alkyl;the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are inhibitors of thromboxane biosynthesis; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent DK-147601-B (DK)
Inventor: PRIESEMUTH WOLFGANG
IPC: C10H21/00
Filed: 1981-12-15
Abstract: 1. An acetylene-gas reactor, particularly for supplying a motor vehicle engine, comprising a calcium-carbide storage container (6), a reaction vessel with water supply device (10) and a sump (14) for the calcium-hydroxide sludge or lime dust produced, characterised in that disposed in vertical alignment under the carbide container (6) is a tubular guide of sievelike construction which is enclosed by the reaction vessel (1) and which is surrounded by an annular jet nozzle arrangement (10) for the supply of the water necessary for the reaction and discharge, via a funnel (13) disposed below the guide (8, 9) into a tubular sump (14) and that the reaction vessel (1) encloses the carbide container (6), the jet nozzle arrangement (10), the water storage tank (20) and the sump (14).
Patent FI-73243-B (FI)
Inventor: SOERENSEN GUNNAR
IPC: C23C/
Filed: 1983-10-17
Granted: 1987-05-29
Abstract: A catalytically active powder, its preparation, and its use for activating insulating substrates to receive electrolessly deposited metal in a coherent metal layer are described. The powder of the invention comprises a plastic powder containing catalyzing/activating chemical compounds allowing that the acceleration of the catalyst is not carried out until the powder is melted down onto the substrate. The substrate need not be etched prior to the metallization since the plastic melted down ensures a good adhesion between metal and plastics and between plastics and substrate. Furthermore, the colloidal nature of the catalyzing compounds is stabilized in a particular and especially durable manner by the plastic powder. The use of the powder causes less risk to the environment since the catalyst may be applied as a dry powder, and since the etching of the substrate is avoided.
Patent FI-78362-B (FI)
Inventor: TERASAKI PAUL I
IPC: A61K35/14
Filed: 1984-05-14
Granted: 1989-03-31
Abstract: A composition of matter and method for using the composition of matter to isolate various cell elements from a heterogeneous cell suspension in a simple one step procedure. The composition is a monoclonal antibody mixture including complement and a non-toxic density gradient media. The composition provides a negative selection technique in which undesired subpopluation cells are lysed and separated from the desired cell subpopulation. The invention has particular application to isolation of white cell elements.
Patent FI-84780-B (FI)
Inventor: MILEWSKI CHRISTIAN
IPC: A61J15/00
Filed: 1986-05-09
Granted: 1991-10-15
Abstract: An apparatus for administering fluids through the nose by means of a tube is provided which comprises a tube having a distal end and a proximal end. The proximal end of the tube when no administration is being carried out is secured in position and disposed removably within the nasal vestibule for the administering. This ensures that during this time when no administering is being carried out, the proximal end of the tube is mounted invisibly within the nose whilst for administering the fluid it can easily be removed from the nasal vestibule and connected to the fluid container.
Patent FI-87702-B (FI)
Inventor: JACQUET BRUNO
IPC: G05G5/06
Filed: 1987-08-13
Granted: 1992-10-30
Abstract: The invention provides a device for selectively preventing actuating modes of a manual control member equipping the face of the case of an apparatus and able to change over from a first position corresponding to a first function, to a second position corresponding to a second function and, from the first position to a third position corresponding to a third function. It includes a cover mounted for pivoting on the case and able to be applied against said face. This cover allows manual access to said member and includes means for allowing this member to change over from the first position to the third position and preventing it changing over from one to the other of the first and second positions.