baber/WOPTO huggingface dataset:
Patent DE-69001461-T2 (DE)
Inventor: ALMGREN KNUT OLLE SEVED
IPC: C07C205/30
Filed: 1990-06-19
Granted: 1993-08-26
Abstract: 4-[3-[ethyl[3-((R*)-(propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy] -benzo n itrile, 4-[3-[ethyl[3-((S*)-(propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy] -benz on itrile, 4-[3-[ethyl[3-((R*)-(propylsulfinyl)propyl]amino]-2(S)-hydroxypropoxy] -benz on itrile, 4-[3-[ethyl[3-[((S*)-(propylsulfinyl)propyl]amino]-2(S)-hydroxypropoxy ]-ben zo nitrile and pharmaceutically acceptable salt thereof, processes for their preparation, as well as the use of said compounds for the preparation of medicaments with action against cardiac arrhythmias.
Patent DE-69017254-T2 (DE)
Inventor: NAKAMURA NORIO
IPC: C07D401/06
Filed: 1990-04-27
Granted: 1995-10-05
Abstract: Compounds of formula (I): <CHEM> [in which R<1> and R<2> is each -R<5>, -CH=CH-R<5> or -C IDENTICAL C-R<5>, in which R<5> is optionally substituted aryl or aromatic heterocyclic; R<3> is hydrogen, alkyl, cyano or -R<5>; X is oxygen or sulphur; A is 1,4-piperazin-1,4-diyl or a 1,4-homopiperazin-1,4-diyl; B is alkylene, carbonyl, thiocarbonyl, sulphinyl or sulphonyl; and R<4> is optionally substituted phenyl] and pharmaceutically acceptable salts thereof have valuable PAF antagonist activity, and may be prepared by reacting a compound containing the piperazine or homopiperazine part of the molecule with a compound containing the other part of the molecule.
Patent DE-69025934-T2 (DE)
Inventor: O'REAR EDGAR
IPC: A61K9/50
Filed: 1990-05-15
Granted: 1996-09-19
Abstract: A composition comprising a plurality of microcapsules suitable for parenteral injection into a mammal comprising a plasminogen activator-containing core, and a semi-permeable biocompatible layer surrounding the core permitting controlled release of at least a portion of the plasminogen activator. A method of reducing the time required for reperfusion of an artery containing a thrombus and a method to reduce the standard dosage requirement of a plasminogen activator in a mammal comprising intravenous injection of a composition comprising a plurality of microcapsules comprising a plasminogen activator core surrounded by a controlled release semi-permeable layer.
Patent DE-69028921-T2 (DE)
Inventor: ROMANAUSKA WILLIAM
IPC: B04B5/02
Filed: 1990-07-17
Granted: 1997-02-27
Abstract: The present invention relates to an applied load accepting band (12) for a centrifuge rotor (10) that is configured such that, while rotating, the applied loads on the band (12) are balanced by the tension in the band (12), so that during rotation the band (12) is subjected only to a tensile force.
Patent DE-69029273-T2 (DE)
Inventor: WEHLING FRED
IPC: A61K9/46
Filed: 1990-09-13
Granted: 1997-06-12
Abstract: The present invention relates to effervescent dosage forms. Formulations in accordance with the present invention are particularly useful for providing medicine to those who cannot or will not swallow a tablet.
Patent DE-69103161-T2 (DE)
Inventor: BUCHBERG AKIVA
IPC: B65D85/00
Filed: 1991-10-24
Granted: 1995-03-09
Abstract: A wrapping for arbitrary objects is formed of a pleated sheet having sides disposed along curves of various shapes. A tape may be attached to the sheet for fixing the pleats and for closing the end openings formed when the sheet is trained around the object. The pleats may increase in size as they progress from one lateral edge to the other.
Patent DE-69110875-T2 (DE)
Inventor: WARD JOHN
IPC: A61P25/28
Filed: 1991-03-20
Granted: 1996-03-21
Abstract: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease.
Patent DE-69116251-T2 (DE)
Inventor: DE SOUZA NOEL JOHN DR
IPC: C07D311/92
Filed: 1991-07-23
Granted: 1996-07-04
Abstract: Process for the manufacture of 6 beta -(3-substitutedamino) propionyloxyforskolin derivatives of the general formula <CHEM> o
Patent DE-69117969-T2 (DE)
Inventor: ROUMAGNAC JEAN-PATRICK
IPC: A23L3/10
Filed: 1991-10-28
Granted: 1996-09-19
Abstract: PCT No. PCT/FR91/00848 Sec. 371 Date May 7, 1993 Sec. 102(e) Date May 7, 1993 PCT Filed Oct. 28, 1991 PCT Pub. No. WO92/08498 PCT Pub. Date May 29, 1992.A holder for objects inside a rotating drum, particularly that of a sterilizer. The holder includes a pressure plate which can be brought into position for holding the objects by a motor-driven mechanism. This mechanism has a rod with threaded portions interacting with sleeves. These sleeves control the movement of pairs of link arms which are rigidly fixed to the pressure plate and are in contact with the drum wall.
Patent DE-69131404-T2 (DE)
Inventor: TREMBLAY PAUL A
IPC: C12P9/00
Filed: 1991-04-16
Granted: 1999-11-25
Abstract: The present invention relates to a process for forming a soluble monovalent salt of a phosphatidyl ester which comprises :   a) reacting a phospholipid with a primary alcohol in the presence of ;     i) an enzyme catalyst phospholipase D ;   ii) a divalent cationic buffer solution and iii) a water immiscible non-ether solvent so as to form the corresponding phosphatide of the divalent cationic salt; and   b) converting the divalent cationic salt to an organic soluble monovalent salt by suspending with a stoichiometric amount of a monovalent salt having a monovalent cation and whose anion forms an insoluble precipitate with the divalent cation.
Patent DE-69131737-T2 (DE)
Inventor: WINTERTON NEIL
IPC: B08B3/08
Filed: 1991-03-27
Granted: 2000-06-08
Abstract: Low molecular weight, fluorine-containing ethers of boiling point 20 DEG C to 120 DEG C are used in solvent cleaning applications.
Patent DE-69133067-T2 (DE)
Inventor: BRECHOT CHRISTIAN
IPC: C07K16/18
Filed: 1991-02-06
Granted: 2003-05-08
Abstract: The invention is directed generally to a DNA sequence coding for human cyclin A and in particular to antibodies, or antisera including such antibodies, which bind to human cyclin A as encoded by the sequence of SEQ ID NO: 1 and which are useful in detecting cellular proliferation. The antibodies of the invention can be polyclonal or monoclonal, and are preferably generated by injection of purified human cyclin A into an animal host. The invention is particularly advantageous because it has been discovered that the gene encoding for human cyclin A is a site for integration of the hepatitis B virus associated with hepatocellular carcinoma, and by detecting human cyclin A through the use of the antibodies of the invention, one can detect and diagnose cell proliferation. Through the use of the present invention, cell proliferation and tumorigenesis can thus be detected at early stages, and such conditions can then be treated or inhibited by the use of anti-sense human cyclin A DNA.
Patent DE-69200011-T2 (DE)
Inventor: CORNIER GERARD
IPC: C03C4/00
Filed: 1992-02-19
Granted: 1994-03-03
Abstract: Glass composition which has the characteristic properties of crystal, namely a relative density of at least 2.90, a refractive index of at least 1.545 and a characteristic sonority and a high clarity, but containing no toxic element and especially neither lead nor barium, characterised in that it contains, as weight percentage:     53.0 to 58.0 of silica SiO2   6.0 to 10.0 of potassium oxide K2O   4.5 to 7.5 of sodium oxide Na2O   0.0 to 9.00 of calcium oxide CaO   0.0 to 12.00 of strontium oxide SrO   16.0 to 21.0 of zinc oxide ZnO   0.5 to 1.5 of antimony oxide Sb2O3   0.0 to 1.5 of aluminium oxide Al2O3   0.0 to 2.5 of tin oxide SnO2   0.0 to 1.2 of boron oxide B2O3   0.0 to 3.0 of lanthanum oxide La2O3   0.0 to 2.0 of titanium oxide TiO2   0.0 to 0.3 of lithium oxide Li2O the sum of the oxides of calcium, strontium and zinc being between 26.5 and 31 % with, as additional conditions:     - when SrO = 0  CaO can range up to 9   - and when SrO  NOTEQUAL  0, CaO is between 0 and the remainder to 31, decreased by SrO + ZnO.
Patent DE-69203327-T2 (DE)
Inventor: QUINN ROBERT
IPC: C07C309/15
Filed: 1992-05-06
Granted: 1995-11-02
Abstract: A process for the preparation of a purified monomer is disclosed which comprises the steps of reacting an impure monomerwherein R1 and R2 are independently hydrogen or alkyl groups containing from 1 to about 6 carbon atoms, with(B) a substantially aqueous solution of an oxide or hydroxide of the structure MO or MOH wherein M is a Group IA or Group IIA metal, or an amine of the structure NR3R4R5 wherein R3, R4 and R5 are independently hydrogen or alkyl, alkanol or alkoxy groups containing from 1 to about 12 carbon atoms,wherein the molar ratio of (A):(B) is from about 1:1-2 for Group IA metals, 2:1-2 for Group IIA metals or ratio of moles of (A) to nitrogens of (B) is from about 1:1-2 nitrogens to form a salt, wherein in order to prevent polymerization of (A), the purified monomer or both or prevent undesired side reactions, the reaction of (A) and (B) occurs at a temperature of between about -20 to 75° C. and at a pH between about 7 to about 12.5, and recovering a purified salt by crystallization in the presence of an oxygen bearing gas stream by subjecting the aqueous solution to changes in temperature and/or pressure and/or concentration.
Patent DE-69208895-T2 (DE)
Inventor: ARDUIN JOEL
IPC: A63C5/075
Filed: 1992-12-02
Granted: 1996-09-05
Abstract: PCT No. PCT/FR92/01120 Sec. 371 Date Jul. 29, 1994 Sec. 102(e) Date Jul. 29, 1994 PCT Filed Dec. 2, 1992 PCT Pub. No. WO93/14837 PCT Pub. Date Aug. 5, 1993A device for modifying the pressure distribution of a ski, such as especially an alpine ski over its gliding surface, as well as to a ski equipped with such a device. The ski is equipped with at least one binding element adapted to retain a boot in the central zone of the middle sole, and at least one support element on which the sole of the boot rests. Moreover, the ski includes a lower base, and above the base, a stiffening blade, both of whose ends are fixedly connected to the base at the front and rear of the middle sole zone. The device includes, in addition, a sensor element in contact with the sole of the boot, mobile along a vertical direction. It also includes a connection between the sensor element and stiffening blade in order to transmit to the blade, in the form of at least one longitudinally or horizontally oriented force in the direction of either one and/or the other of its ends, at least a portion of the downward vertical thrust of the boot captured by sensor element.
Patent DE-69215477-T2 (DE)
Inventor: MASAAKI NOSAKA
IPC: F26B17/20
Filed: 1992-01-09
Granted: 1997-03-27
Abstract: The invention is directed to an apparatus for drying powdered or granular materials comprises a drying tank (1) including a transversely extending drying room (7) adapted to be applied with heating by microwaves, at least one partition (20) defining more than two drying zones in the drying room (7) of the drying tank (1), a rotary shaft (12) disposed in the drying tank (1) in its longitudinal direction to extend through the drying room (7) in a manner of being freely rotatable and agitating blades (30a),(30b)... provided on the rotary shaft correspondingly to each drying zone, microwave application units (40) provided for each drying zone, and temperature sensors (50) for each drying zone and corresponding temperature adjusters (51) connected to the respective temperature sensors (50). <IMAGE>
Patent DE-69221845-T2 (DE)
Inventor: WASHIDA NAOHIRO
IPC: C12R1/91
Filed: 1992-12-23
Granted: 1998-04-09
Abstract: Monoclonal antibodies specifically bind to human immunoglobulin E (IgE) and are characterized by the following properties.   1/ &cir&  Molecular weight of approximately 150,000 determined by SDS-polyacrylamide gel electrophoresis (non-reduced state).   2/ &cir&  Bind to human IgE-producing B cells. 3/ &cir&  Recognize IgE bound to human or canine cell having Fc epsilon receptor. 4/ &cir&  Antibodies having one of sequences No. 1 to 4 in the sequence list of N-terminal amino acid of L-chain.   The antibodies bind specifically to IgE and are useful for the treatment of allergy and other medicines. <IMAGE>
Patent DE-69227750-T2 (DE)
Inventor: CONDER MICHAEL J
IPC: C12R1/82
Filed: 1992-10-14
Granted: 1999-04-22
Abstract: Important intermediates for preparing cephalosporin antibiotics, 7-amino-cephalosporanic acid (7-ACA) and 7-aminodeacetylcephalosporanic acid (7-ADAC), are prepared by a novel bioprocess in which a transformed Penicillium chrysogenum strain is cultured in the presence of an adipate feedstock to produce adipoyl-6-APA (6-amino penicillanic acid); followed by the in situ expression of the following genes with which the P. chrysogenum has been transformed:   1) an expandase gene, e.g., from Cephalosporium acremonium, whose expression product converts the adipoyl-6-APA by ring expansion to adipoyl-7-ADCA; 2) an hydroxylase gene whose expression product converts the 3-methyl side chain of adipoyl-7-ADCA to 3-hydroxymethyl, to give the first product, adipoyl-7-aminodeacetylcephalosporanic acid (7-ADAC); and 3) an acetyltransferase gene whose expression product converts the 3-hydroxymethyl side chain to the 3-acetyloxymethyl side chain of adipoyl-7-ACA. The final product, 7-ACA, is then prepared by cleavage of the adipoyl side chain using an adipoyl acylase. The entire synthesis, accordingly, is carried out using bioprocesses, and is efficient and economical.
Patent DE-69227843-T2 (DE)
Inventor: LAAKSONEN PAAVO
IPC: F16L57/00
Filed: 1992-09-02
Granted: 1999-07-29
Abstract: The invention relates to a method of protecting a pipe end. According to the invention, a film (2) covering the pipe end is attached to the end surface of the pipe (6) by welding or other similar sealing method. <IMAGE>
Patent DE-69230108-T2 (DE)
Inventor: WELANDSSON GOESTA
IPC: E04F11/18
Filed: 1992-12-21
Granted: 2000-05-18
Abstract: A coupling device for pipes such as staircase banisters, comprising two chuck devices (1, 2) expandable away from one another by means of screws (3) and which are disposed interiorly in those pipes which are to be coupled, and bridging the joint. The chuck devices (1, 2) have clamping surfaces (4) which are complementary to the interior surfaces of the pipes, and the pipes have aperturess for access of the screws (3). The clamping surfaces (4) are band-shaped and transversely directed in relation to the longitudinal direction of the coupling device and are spaced apart by recessed surface portions (5). The chuck devices (1, 2) are in the form of semicylindrical shell-shaped bodies with partly exteriorly transversely directed rigidifying beads whose peaks have the clamping surfaces, and partly interiorly longitudinal rigidifying beads.
Patent DE-69301486-T2 (DE)
Inventor: PHILIPPE MICHEL
Filed: 1993-03-23
Granted: 1996-06-27
Abstract: The invention relates to the use, as pigment in cosmetic compositions, of 5H-dinaphthol[2,3a:2',3'-c]carbazole-6,11,12,17-tetrone and to cosmetic compositions such as foundations, tinted creams, mascaras, blushers, eye shadows, lipsticks and nail varnishes.
Patent DE-69304615-T2 (DE)
Inventor: BROWN CHARLES RUPERT T
IPC: A23L29/20
Filed: 1993-06-03
Granted: 1997-02-20
Abstract: A process for the preparation of an edible dispersion comprising at least two gelling agents forming at least two distinct phases, said process comprising the steps of:   (1) providing a mixture of the gelling agents in water at an elevated temperature above the gel-forming temperature of two or more of these gelling agents; and (2) cooling said mixture while applying shear until at least one of said distinct phases is gelled; with the proviso that the dispersion as prepared by this method has a different phase structure than the same dispersion when prepared under quiescent conditions.
Patent DE-69309573-T2 (DE)
Inventor: FERRERO PIETRO
IPC: B65G17/00
Filed: 1993-08-12
Granted: 1997-09-11
Abstract: The line comprises one or more movable entrainment formations, for example motor-driven (5, 6) belts (4). Moulds (2) are supported on the belts without restraint and are entrained by the belts (4) as a result of being supported on the upper passes thereof. The advance of the moulds (2) can be stopped selectively by stop means (10, 11) which engage the moulds (2) in a coupling relationship, stopping them, whilst the moulds (2) slide on the upper passes of the belts (4) which are kept in motion. <IMAGE>
Patent DE-69314501-T2 (DE)
Inventor: DAUTZENBERG JOSEPH HUBERTUS
IPC: G11B23/00
Filed: 1993-07-05
Granted: 1998-04-16
Abstract: The invention is a device for removing compact discs from their containers. The top of the device rests on the mounting elements in the holder tray. Two or more spring elements are attached to the cylindrical section of the device, which fits between but does not touch the mounting elements. The spring elements are smaller than the gaps between the mounting elements and rest lightly against the compact disc. A cam prevents the device from rotating, and cams are also provided to prevent the device from dropping out. When the device is pressed down, the mounting elements move toward each other and the compact disc is released and pressed upwards by the spring elements so that the compact disc can be removed.
Patent DE-69315100-T2 (DE)
Inventor: YABUSAKI TATSUMI
IPC: G06F11/00
Filed: 1993-03-02
Granted: 1998-06-10
Abstract: A programmable controller that allows input and output modules to be changed during an on-line mode with minimal interaction by the user. The controller includes a request table that separately stores change request signals generated by each module. In a first embodiment, the controller periodically polls this request table to determine whether any module has issued a change request. The controller disables each module that issues a change request. When a new module is loaded, the controller enables this module once the corresponding change request signal is removed from the request table. In a second embodiment, the controller uses an interrupt circuit to interrupt processing when a change request is initiated.
Patent DE-69316660-T2 (DE)
Inventor: YOUNG JAMES
IPC: A61K31/445
Filed: 1993-08-03
Granted: 1998-05-07
Abstract: Use of a composition comprising a compound of formula I:   
or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for use in providing symptomatic relief from dermal irritation, wherein the induction of cardiac arrhythmia is avoided, said treatment comprising administering a therapeutically effective amount of a compound of formula I to a human patient whose hepatic function is not impaired.
Patent DE-69322500-T2 (DE)
Inventor: SMALL JAMES
IPC: C08K7/14
Filed: 1993-02-19
Granted: 1999-04-29
Abstract: The present invention relates to polyester/polycarbonate blends having improved low temperature impact strength and processability. More particularly, this invention relates to a thermoplastic molding composition containing an aromatic carbonate polymer, a poly(1,4-cyclohexylenedimethylene terephthalate) (PCT) resin, and a copolyester which consists essentially of repeat units from mixtures of isophthalic acid, terephthalic acid and 1,4-cyclohexanedimethanol.
Patent DE-69329698-T2 (DE)
Inventor: MICHALCZYK JOSEPH
IPC: C08G77/50
Filed: 1993-09-15
Granted: 2001-04-05
Abstract: Single component inorganic/organic network materials incorporating the physical properties of glasses with the flexibility of organic materials of empirical formula X(SiO1.5)n wherein X is one or more flexible organic linkages and n is greater than or equal to 2, as well as precursors thereof, are disclosed.
Patent DE-69332378-T2 (DE)
Inventor: HIGO NARUHITO
IPC: A61K47/38
Filed: 1993-07-23
Granted: 2003-07-10
Abstract: A percutaneously administrable base composition which facilitates the percutaneous absorption of drugs and is remarkably reduced in the irritancy against the skin. The composition comprises 10-60 wt. % of lower alcohol, 10-50 wt. % of humectant, 10-70 wt. % of water, 0.1-15 wt. % of abirritant and 0.1-15 wt. % of absorption promoter. A drug composition is prepared by adding to the above composition various active ingredients such as antitussive, expectorant, skeletal muscle relaxant, antivertiginous drug, narcotic, drug for the circulatory system, and so forth.
Patent DE-69333084-T2 (DE)
Inventor: ANDERSSON OWE
IPC: C01F11/22
Filed: 1993-05-27
Granted: 2003-12-18
Abstract: PCT No. PCT/SE93/00469 Sec. 371 Date Nov. 23, 1994 Sec. 102(e) Date Nov. 23, 1994 PCT Filed May 27, 1993 PCT Pub. No. WO93/24261 PCT Pub. Date Dec. 9, 1993The invention relates to an additive for improving the machinability of iron-based powder compositions. The additive contains a combination of calcium fluoride particles and barium fluoride particles, which is included in an amount of 0.1-1.0% by weight in the powder composition. Further, the invention relates to powder compositions containing the indicated additives, as well as sintered products produced from the powder compositions.
Patent DE-69333606-T2 (DE)
Inventor: AKAOGI TAKAO
IPC: G11C16/34
Filed: 1993-06-25
Granted: 2005-09-15
Abstract: A semiconductor memory device having electrically erasable nonvolatile memory cells to and from which data is automatically written and erased according to an internal algorithm incorporated in said semiconductor memory device. The allowable value of write or erase operations is determined according to the internal algorithm, which is variable. Thus, a device embodying the present invention can carry out a delivery test with "n" rewrite operations at the most, and taking into account deterioration due to an increase in the number of rewrite operations, can guarantee the maximum number of rewrite operations N (N>n) possible by a user. <IMAGE>
Patent DE-69403085-T2 (DE)
Inventor: JONES ALLAN
IPC: C08K5/07
Filed: 1994-08-08
Granted: 1997-08-14
Abstract: This invention relates to naphthalenedicarboxylic acid containing polymer compositions having reduced fluorescence. More specifically, the process involves melt blending a naphthalenedicarboxylic acid containing polymer with 0.1 to 5 weight percent of a fluorescence quenching compound selected from a halogen containing aromatic compound, an aromatic ketone or a naphthol compound and thermoforming the blend into an article. The blends are useful for packaging applications where clarity and/or aesthetic appeal are of concern.
Patent DE-69409782-T2 (DE)
Inventor: UCHIDA HIROSHI
IPC: B28B1/00
Filed: 1994-08-24
Granted: 1998-08-13
Abstract: A method of producing a pattern-carrying molded body (10) which is provided on a part or the whole of a surface thereof with a pattern layer of a predetermined thickness displaying a delicate and beautiful pattern, and which is molded out of concrete, an artificial stone, a ceramic material, a metal or a plastic. This molded body (10) has a layer (13) of dry pulverized bodies attached to an object surface (12), and the material attached to the surface (12) is raked in accordance with a pattern (16) to be formed, by a raking member provided on a predetermined position on the surface (12). Dry pulverized bodies (15) different from those of the layer (13) are packed in a recess (14) formed by this racking operation, and the pulverized bodies thus packed are solidified as they are or with a lining layer (11) laminated, in such a manner that the packed pulverized bodies are solidified unitarily with the molded body (10).   <IMAGE>