baber/WOPTO huggingface dataset:
Patent CA-3124443-A1 (CA)
Inventor: ZHANG TIANHE
IPC: A61N1/372
Filed: 2017-08-23
Abstract: A system includes electrodes on at least one lead (2280) configured to be operationally positioned for use in modulating a volume of neural tissue, a neural modulation generator configured to deliver energy using at least some electrodes to modulate the volume of neural tissue and a programming system configured to program a modulation parameter set, including determine electrode fractionalizations for the electrodes based on a target multipole. The modulation parameter set may include the electrode fractionalizations. The neural modulation generator may be configured to use the modulation parameter set to provide a linear electric field over the volume of tissue.
Patent CA-3125906-A1 (CA)
Title: Reset mechanism for electronic throttle body
Inventor: DAI YIFENG
IPC: F02D9/10
Filed: 2020-01-13
Abstract: A reset mechanism for an electronic throttle body comprises a valve (19), a throttle shaft (20), a reset gear (21), an upper spring seat (11), a lower spring seat (13), and a reset spring (12). A support leg (14) is disposed at an outer axis of the reset gear. The upper spring seat, the reset spring, and the lower spring seat are sleeved on the reset gear. Two ends of the reset spring are fixed to the upper spring seat and the lower spring seat, respectively. The upper spring seat has an upper support leg surface (16) attached to a first side of a valve limiting block and a side of the support leg. The lower spring seat has a lower support leg surface (15) attached to a second side of the valve limiting block and another side of the support leg. The mechanism has a simple structure and a simplified manufacturing process, and can easily and accurately control the default position of the throttle body.
Patent CA-3132387-A1 (CA)
Inventor: CHE JIANWEI
IPC: A61K31/4523
Filed: 2020-04-23
Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))) to induce degradation of the target protein CDK9 and/or CDK12. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers (e.g., ovarian cancer, breast cancer, or prostate cancer))). Provided also are methods of inducing the degradation of the target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))), and methods of inducing apoptosis in a cell in a biological sample or subject by administering the bifunctional compound or composition described herein.
Patent CA-3133038-A1 (CA)
Title: Composition pharmaceutique pour le traitement de la sclerose laterale amyotrophique
Inventor: HONMOU OSAMU
IPC: A61P25/28
Filed: 2020-03-13
Abstract: La présente invention concerne une composition pharmaceutique pour le traitement de la sclérose latérale amyotrophique. Plus particulièrement, la présente invention concerne une composition pharmaceutique qui est destinée à traiter la sclérose latérale amyotrophique et qui est caractérisée en ce qu'elle contient des cellules souches mésenchymateuses et qui est administrée par voie intraveineuse.
Patent CA-3134388-A1 (CA)
Title: Subscription based travel service
Inventor: HANDLER BRENT
IPC: G06Q30/08
Filed: 2020-02-28
Abstract: Systems and methods are disclosed for providing a subscription travel service. The systems and methods include operations for receiving travel information with a travel date for a user; computing a subscription value as a function of a booking date and the travel date; determining a minimum travel value and a maximum purchase amount based on the computed subscription value; searching a list of travel services that are available on the travel date to identify candidate travel services each having a first cost that exceeds the minimum travel value; selecting a subset of the candidate travel services that each have a second cost that is less than the maximum purchase amount; and generating for display to a user, in a graphical user interface, one or more interactive visual representations of the selected subset of the candidate travel services.
Patent CA-3135630-A1 (CA)
Title: Canola hybrid 19gn2390g
Inventor: KOSCIELNY CHADWICK BRUCE
IPC: A01H5/00
Filed: 2021-10-25
Abstract: Provided is a canola variety designated 19GN2390G and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a canola variety comprise crossing canola variety 19GN2390G with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into 19GN2390G through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby are described. Canola variety 19GN2390G, the seed, the plant produced from the seed, plant parts and variants, mutants, and minor modifications of canola variety 19GN2390G are disclosed.
Patent CA-3140386-A1 (CA)
Title: Modified viral particles and uses thereof
Inventor: SABIN LEAH
IPC: C12N15/50
Filed: 2020-05-22
Abstract: Provided herein are compositions and methods for adapting adeno-associated virus (AAV) particles comprising capsids of non-primate animal AAV, remote AAV, or a combination thereof. AAV adapted accordingly may be a viable gene therapy platform for the treatment of a patient in need thereof, and may be particularly useful in patients excluded from current treatment modalities involving current therapeutic AAV particles due to their high titer of antibodies against the current therapeutic AAV particles.
Patent CA-3141420-A1 (CA)
Inventor: JAMES MALCOLM BARRY
IPC: B29C33/04
Filed: 2020-11-27
Abstract: A fluid phase change thermal management cooling method and apparatus for removing heat from a source of heat, the method comprising the steps of: filling a cooling chamber with volume V1 of a fluid phase change thermal management cooling apparatus with a fluid in its liquid phase; increasing the volume of the cooling chamber to volume V2 to va-pourise a portion of the fluid from its liquid phase to its vapour phase such that there is substantially only the fluid in its liquid phase and fluid in its vapour phase within the volume V2; allowing a dwell time that provides for at least some of the fluid in its liquid phase that has contact with a heated surface of the cooling chamber to be vaporised; and repeating the steps where timing of the steps and dwell time between steps is selected to control heat build-up within selected limits.
Patent CA-3142559-A1 (CA)
Title: Aircraft and method of operating an aircraft comprising an air separation device
Inventor: CASADO MONTERO CARLOS
IPC: B64D13/00
Filed: 2021-12-15
Abstract: The invention relates to an aircraft and a method for operating an aircraft, which comprises a combustion engine with a combustion chamber and an injection device for injecting fuel in the combustion chamber, said aircraft comprising as well an air separation device adapted to separate air into an oxygen-enriched gas mix and an nitrogen-enriched gas mix, said oxygen-enriched gas mix being injected into the combustion chamber with the fuel, while the nitrogen-enriched gas mix is used to inert at least some portions of the aircraft in the environment of said combustion engine.
Patent CA-3144035-A1 (CA)
Inventor: DARGATZ MICHELLE
IPC: C12Q1/689
Filed: 2020-07-06
Abstract: The invention pertains to a method for determining the risk of an Avian Pathogenic E. coli (APEC) infection in an avian flock, the method comprising determining the quantitative ratios of the amount of specific virulence factors (VF), each with respect to the amount of E. coli reference gene is ybbW (SEQ ID NO: 6) or functional fragments thereof, in a pooled sample deriving from the avian flock, wherein the specific virulence factors include at least the genes iroN (SEQ ID NO.: 1) and ompT (SEQ ID NO: 2) or functional fragments thereof.
Patent CA-3145112-A1 (CA)
Title: Engineered nucleic acid regulatory element and methods of uses thereof
Inventor: QIAO CHUNPING
IPC: C12N15/85
Filed: 2020-07-24
Abstract: The present invention relates to nucleic acid expression cassettes that are engineered to enhance gene expression. Vectors and methods employing the expression cassettes containing novel chimeric regulatory elements are provided. The invention is particularly useful for delivery of transgenes to target cells and confers desirable properties for liver- directed and muscle-directed or liver-directed and bone-directed gene therapy. Moreover, the invention relates to a novel method of engineering tandem enhancer/ promoter elements and expressing transgenes for example within liver and/or muscle cells, and delivery of therapeutics for treating various disorders.
Patent CA-3145567-A1 (CA)
Inventor: LI LONGCHENG
IPC: C12N15/63
Filed: 2020-07-03
Abstract: Disclosed are an oligomeric nucleic acid and the use thereof in treating hearing loss. Also disclosed is a small activating nucleic acid molecule for treating hearing loss. The small activating nucleic acid molecule may be a double-stranded or single-stranded RNA molecule targeting the promoter region of an ATOH1 gene, comprising a first nucleic acid strand and a second nucleic acid strand. The double-stranded RNA molecule targeting the promoter region of the ATOH1 gene comprises two nucleic acid strands of 16-35 nucleotides in length, and either of the nucleic acid strands has at least 75% homology or complementarity with a target selected from the promoter region of the ATOH1 gene. The method of using the small activating nucleic acid molecule and a pharmaceutical composition optionally containing a pharmaceutically acceptable carrier can up-regulate the expression of the ATOH1 gene and the protein in cells and can treat diseases or conditions related to insufficient or decreased expression of the ATOH1 gene.
Patent CA-3146081-A1 (CA)
Title: Methods and compositions related to target analysis
Inventor: NGUYEN HUY QUOC
IPC: C12Q1/6813
Filed: 2020-07-30
Abstract: The technology described herein is directed to methods, systems, and compositions for analyzing, detecting, and/or visualizing target molecules. Described herein are compositions and systems comprising oligonucleotide tags comprising barcoded cassettes. Also described herein are methods for analyzing target molecules, the method comprising contacting a sample with at least one oligonucleotide tag, contacting the sample with at least two readout molecules, and detecting the relative spatial order of the readout molecules.
Patent CA-3148166-A1 (CA)
Title: Systems for the classification of interior structure areas based on exterior images
Inventor: STRONG SHADRIAN
IPC: G06K9/62
Filed: 2020-10-15
Abstract: Methods and systems are disclosed, including a computer system configured to automatically determine home living areas from digital imagery, comprising receiving digital image(s) depicting an exterior surface of a structure with exterior features having feature classification(s) of an interior of the structure; processing the depicted exterior surface into exterior feature segments with an exterior surface feature classifier model, each of the exterior feature segments corresponding to exterior feature(s); project each of the plurality of exterior feature segments into a coordinate system based at least in part on geographic image metadata, the projected exterior feature segments forming a structure model; generate a segmented classification map of the interior of the structure by fitting one or more geometric section into the structure model in a position and orientation based at least in part on the plurality of exterior feature segments.
Patent CA-3148800-A1 (CA)
Inventor: DERAIL CHRISTOPHE
IPC: A61L15/42
Filed: 2020-07-30
Abstract: The invention relates to a new composition based on: ABA triblock copolymers comprising two thermoplastic styrene terminal blocks A and a central elastomer block B that is a saturated olefin; and at least one polyisobutene having a very low molecular weight; and optionally an AB diblock copolymer. The present composition has interesting properties similar to those of silicone elastomers. The invention also relates to a wound dressing comprising such an elastomer composition.
Patent CA-3148987-A1 (CA)
Inventor: HINDERLITER BRANDON N
IPC: F01D15/10
Filed: 2020-07-30
Abstract: L'invention concerne un système d'alimentation d'un équipement de fracturation hydraulique électrique, le système comprenant un système de stockage d'énergie et un équipement de fracturation hydraulique à alimentation électrique en communication électrique sélective avec le système de stockage d'énergie. Le système comprend en outre au moins un disjoncteur entre le système de stockage d'énergie et l'équipement de fracturation hydraulique à alimentation électrique, le disjoncteur étant conçu pour faciliter ou empêcher une communication électrique entre le système de stockage d'énergie et l'équipement de fracturation hydraulique à alimentation électrique.
Patent CA-3151635-A1 (CA)
Inventor: TSUKASHIMA ROSS
IPC: A61B1/313
Filed: 2020-08-21
Abstract: La présente invention concerne une canule comprenant un appareil de prise de vues monté de façon proximale et des sources lumineuses montées de façon proximale. Les sources lumineuses possèdent des axes de faisceau dirigés de façon distale, vers un espace de travail au niveau de l'extrémité distale de la canule. Les sources lumineuses sont couplées à des lentilles de focalisation, pour réduire l'angle de faisceau des sources lumineuses et réduire l'éblouissement à l'intérieur du tube de la canule.
Patent CA-3152607-A1 (CA)
Title: A rack system for housing an electronic device
Inventor: CHEHADE ALI
IPC: H05K7/20
Filed: 2022-03-17
Abstract: A rack system for housing an electronic device comprises an immersion case configured to provide housing to the electronic device. The immersion case includes a first wall, and a second wall.  The first wall and the second wall define means for controlling deformation of the immersion case, such that when an immersion cooling liquid is inserted in the immersion case, the means for controlling deformation limit the deformation of the immersion case.
Patent CA-3152855-A1 (CA)
Inventor: BRIDEWELL VICTORIA
IPC: D04H1/4309
Filed: 2020-09-30
Abstract: Disclosed herein are unit dose articles comprising a packet with an outer wall which comprises a nonwoven web comprising sulfonate modified PVOH fiber forming materials and/or a blend of fiber forming materials comprising polyvinylpyrrolidone and a sulfonate modified PVOH, carboxyl modified PVOH, or both. Also disclosed herein, are said unit dose articles comprising a composition including a harsh chemical.
Patent CA-3155355-A1 (CA)
Title: Switch devices and methods for moving switch rails
Inventor: DWORSCHACK DAVID
IPC: B61L5/06
Filed: 2022-04-14
Abstract: A switch device for moving switch rails. The switch device includes a motor operatively coupled to move the switch rails into and between first and second positions. The motor is configured for electricity to flow therethrough along a first path and a second path. A first path relay has two normally open contacts each within the first path, where activating the first path relay closes the two normally open contacts thereof. A second path relay has two nomially open contacts each within the second path, where activating the second path relay closes the two normally open contacts thereof. The motor moves the switch rails towards the first position when the first path relay is activated and the second path relay is deactivated, and the motor moves the switch rails towards the second position when the second path relay is activated and the first path relay is deactivated.
Patent CA-3155724-A1 (CA)
Title: Heterocyclic compounds
Inventor: BENZ JOERG
IPC: A61P25/14
Filed: 2020-09-22
Abstract: The invention provides new heterocyclic compounds having the general formulae (Ia) and (Ib) (Formula Ia, Ib) wherein A, B, and L are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
Patent CA-3155965-A1 (CA)
Title: Composes herbicides
Inventor: BURTON PAUL MATTHEW
IPC: C07D271/04
Filed: 2020-11-13
Abstract: La présente invention concerne des composés de formule (I) dans laquelle Q, R2, R3 et R4 sont tels que définis dans la description. L'invention concerne en outre des compositions comprenant lesdits composés, et des procédés de lutte contre les mauvaises herbes au moyen desdits composés et/ou compositions.
Patent CA-3156790-A1 (CA)
Inventor: HARAZIM WOLFGANG
IPC: F01K13/00
Filed: 2020-10-22
Abstract: L'invention concerne un procédé pour convertir de l'énergie thermique en énergie électrique sur la base d'un cycle à régénération thermique inverse combiné à une accélération thermique, ainsi que son utilisation, ce procédé pouvant être utilisé en première ligne dans le domaine de la production d'énergie. Les besoins énergétiques croissants à l'échelle planétaire augmentent l'impact anthropique sur le climat et l'environnement, puisque selon l'état de la technique, ce sont principalement des sources d'énergie fossile, fondées sans exception sur des processus de conversion d'énergie thermique dans le sens horaire, qui sont brûlées pour assurer la mobilité et la production d'électricité, les effets secondaires étant la chaleur dissipée et les gaz perdus. L'objectif de cette invention est de réduire l'impact anthropique sur le climat et l'environnement au moyen d'un nouveau procédé de base. Les processus de réfrigération à compression de vapeur de type cycle inverse nécessitent effectivement, à des fins d'entraînement, un travail de compression. Ils permettent néanmoins une régénération thermique, puisque la réfrigération nécessaire à la condensation s'effectue à un niveau de pression et de température plus élevé que la vaporisation. Si lors du changement de phase, l'augmentation de volume est encore utilisée pour accroître la vitesse fluidique dans la section transversale d'écoulement (accélération thermique), alors la quantité d'énergie d'écoulement extractible générée lors du procédé pour la production d'électricité est supérieure à celle que nécessite la circulation interne. Cette invention concerne en outre un processus de conversion d'énergie thermique inverse.
Patent CA-3159600-A1 (CA)
Title: Materials and methods for standardizing diffusion of a fluid into tissues
Inventor: BAUER DANIEL
IPC: G01N13/00
Filed: 2016-02-05
Abstract: The subject disclosure presents systems and methods for evaluating a tissue sample that has been removed from a subject. Movement of fluid through the tissue sample is monitored by measuring time of flight of acoustic waves passed through the tissue sample. A system for performing the method can include a transmitter that outputs the energy and a receiver configured to detect the transmitted energy. Using the methods and systems, an optimized protocol for ensuring adequate distribution of the fluid throughout a variety of tissues can be developed.
Patent CA-3163746-A1 (CA)
Title: Needling devices and penetration depths
Inventor: CHASTAIN DAVID
IPC: A61B17/34
Filed: 2020-12-04
Abstract: A needling device includes a plurality of needles forming a needle array, and a motor assembly for driving the needle array, where each of the plurality of needles includes a needle tip at one end, and tapers at a taper angle and along a taper length to a maximum needle diameter at the other end, and in use, a skin reference surface of the needling device is in contact with a subject's skin.
Patent CA-3166493-A1 (CA)
Inventor: WARREN REMY
IPC: A61F5/48
Filed: 2021-01-08
Abstract: La présente invention concerne un dispositif pour l'incontinence urinaire de stress conçu pour limiter ou empêcher une fuite urinaire chez un individu. Le dispositif comprend un corps comprenant une partie interne entourée par une partie externe. La partie externe comprend un matériau biocompatible et présente une face de contact opposée à une face de guidage. La face de contact est conçue pour occlure l'ouverture urétrale de l'individu. Un guide ayant une partie intérieure entourée par une partie extérieure fait saillie à partir de la face de guidage pour aider à l'application du dispositif sur le méat urétral sous les petites lèvres et au-dessus de l'ouverture vaginale de l'individu. Le dispositif comprend des matériaux qui le rendent réutilisable.
Patent CA-3168766-A1 (CA)
Title: Appareil, systemes et procedes d'injection de medicament
Inventor: ANTHONY JULIA
IPC: A61M5/31
Filed: 2021-02-26
Abstract: L'invention concerne des systèmes, des procédés et un appareil pour stocker, transporter, mélanger, et injecter un médicament en tant que solution, et dans certains modes de réalisation, un appareil et à un système d'injection de médicament destinés à être utilisés pour mélanger à la demande un médicament avec un liquide, tel que de l'eau, dans une quantité et un dosage prémesurés, et pour injecter le mélange de médicament à l'aide d'un ensemble aiguille hypodermique intégré. L'invention concerne également des procédés d'utilisation de tels appareils et systèmes.
Patent CA-3171955-A1 (CA)
Inventor: Clancy Sean
IPC: A23L33/135
Filed: 2022-09-02
Abstract: Il est décrit un système, un processus, des produits riches en nutriments et leurs utilisations générés par la conversion de dérivés fruitiers dun établissement vinicole en des produits riches en nutriments effectuée de manière écologique. Lintégration de ce système dans un établissement vinicole aide ce dernier à gérer de manière écologique ce qui était considéré comme des déchets par le passé, ce qui pourrait fournir un nouveau flux de rentrée à létablissement. Le système et le processus sont utilisés afin de convertir des dérivés de vinification en des produits bioactifs riches en nutriments et/ou en des ingrédients alimentaires comprenant des antioxydants ou dautres molécules bioactives demeurant au sein du marc et des lies. Ces produits riches en nutriments peuvent être utilisés comme saveur naturelle et amplificateurs de la texture et de la couleur en plus des ingrédients nutritionnels, afin de fortifier les aliments transformés et les recettes des consommateurs. Ils peuvent également être utilisés en tant que suppléments de santé et dans lindustrie cosmétique.
Patent CA-3172758-A1 (CA)
Title: Method and system for automatically diarising a sound recording
Inventor: GHAEMMAGHAMI HOUMAN
IPC: G10L17/06
Filed: 2017-07-11
Abstract: Embodiments of the present invention provide methods and systems for performing automatic diarisation of sound recordings including speech from one more speakers. The automatic diarisation has a development or training phase and a utilisation or evaluation phase. In the development or training phase background models and hyperparameters are generated from already annotated sound recordings. These models and hyperparameters are applied during the evaluation or utilisation phase to diarise new or not previously diarised or annotated recordings.
Patent CA-3173298-A1 (CA)
Title: Systemes et procedes de perforation de surface de tissu
Inventor: SCHERR DOUGLAS
IPC: A61B17/28
Filed: 2021-02-27
Abstract: L'invention concerne un système, comprenant un guide d'aiguille définissant un trajet de déplacement d'une aiguille insérée à travers le guide, et un manipulateur de tissu conçu pour approcher le tissu et le guide d'aiguille et pour positionner au moins une partie du tissu dans le trajet de déplacement de l'aiguille, et le manipulateur de tissu et le guide d'aiguille pouvant être alignés de telle sorte que le trajet de déplacement traverse une même surface du tissu une pluralité de fois.