baber/WOPTO huggingface dataset:
Patent CA-2446460-A1 (CA)
Inventor: ST-LOUIS MARIE-CLAUDE
IPC: C07K14/155
Filed: 2003-11-05
Abstract: The regulatory proteins Tat and Rev are essential to bovine immunodeficiency virus (BIV) replication at the transcriptional and post-transcriptional level, respectively. Previous studies have shown that BIV may encode two types of Tat proteins of 103 and 108 amino acids, respectively. Here, we report the identification and characterization of a new BIV Tat protein (composed of 236 amino acids) (Tat236) derived from a tat/rev cDNA. The tat/rev cDNA was obtained by reverse transcription-PCR from RNA extracted from cells infected with BIV isolated by co-cultivation of FBLU  cells with the spleen cells of rabbits exposed for 3 years to the R29 isolate of BIV.  Sequence analysis indicated that BIV Tat236 contains the first 98 amino acids of Tat103 and the 3' end 138 amino acids of Rev. Reporter gene assays indicated that transactivation of BIV long terminal repeat (LTR) by Tat236 is higher than by the original BIV Tat proteins in Cf2Th, FBLU, 293A and Hela cells. In addition, BIV Tat236 protein cross-transactivated the human immunodeficiency virus (HIV-1) promoter more efficiently than that observed with BIV Tat103 in Cf2Th cells. Tat236 deletion mutants showed that the predicted basic domain of Rev within Tat236 plays a major role in the observed enhanced transactivation activity of the protein. However, the intact functional domain of the original BIV Tat is required for efficient transactivation. This is the first report of a hybrid Tat protein from BIV or any lentiviruses that shows higher transactivation than the original transactivator Tat proteins.
Patent CA-2447746-A1 (CA)
Title: Cycloalkenylsulfonamide derivatives
Inventor: CANTRELL BUDDY EUGENE
IPC: A61P25/28
Filed: 2002-05-17
Abstract: The present invention provides certain cycloalkenylsulfonamide derivatives of the formula: useful for potentiating glutamate receptor function in a patient and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders X-14889.
Patent CA-2449508-A1 (CA)
Inventor: COCHRAN DON W
IPC: G01N25/72
Filed: 2002-05-21
Abstract: L'invention concerne un appareil et un procédé d'imagerie infrarouge thermique instantanée utilisés dans des applications automatisées de contrôle d'articles et de commande de processus. L'invention concerne en particulier l'utilisation de capteurs (20) d'imagerie zone-réseau à sels de plomb en mode instantané en tant qu'unité frontale d'imagerie dans des systèmes (12) de contrôle de vision artificielle à grande vitesse. Leur coût relativement faible, leur sensibilité de mesure à des températures compatibles avec des organes de refroidissement thermoélectriques, et leur capacité d'exploitation en mode instantané permet d'utiliser les capteurs (20) d'acquisition d'image à sels de plomb dans diverses applications automatisées de contrôle d'articles et de commande de processus.
Patent CA-2449515-A1 (CA)
Title: Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
Inventor: MALM JOHAN
IPC: C07C65/26
Filed: 2002-08-13
Abstract: This invention relates to novel compounds which are thyroid receptor ligands , preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.
Patent CA-2450695-A1 (CA)
Inventor: LINTON JOHN
IPC: G01N21/65
Filed: 2002-06-04
Abstract: A system and method high throughput sample preparation and analysis using column chromatography. Each port in a plurality of ports has a port input th at interfaces with a first fluid source and a port output. A fluidic circuit is coupled to each port output and to a second fluid source, the fluidic circui t for controlling fluid flow from the plurality of ports and the second fluid source. The fluidic circuit is also coupled to a plurality of chromatography columns. An interface to an analyzer receives output from at least one of th e plurality of chromatography columns. The plurality of chromatography columns is moved relative to the analyzer via a translation stage, such that sample output from one of the plurality of chromatography columns can be selectivel y presented to the analyzer.
Patent CA-2451014-A1 (CA)
Title: Dispositif de raccordement entre une tubulure et un carter de filtration
Inventor: LESCOCHE PHILIPPE
IPC: B01D63/06
Filed: 2003-03-21
Abstract: L'objet de l'invention concerne un dispositif pour relier à l'aide de systèm es de raccordement de divers types, une tubulure (2) à un carter de filtration (3). Selon l'invention, le dispositif comporte : une plaque de tête (21) indépendante du type du système de raccordement, fixée sur le carter (3) et munie de passages (22) s'ouvrant sur une face d'appui (23) de la plaque de tête, pour chaque contre-plaque (P1) de type donné, une première face d'appu i (25) complémentaire à celle (23) de la plaque de tête (21) et une deuxième face d'appui (29) adaptée pour coopérer avec une contre-bride (B1) du type correspondant, un joint d'étanchéité (28) interposé entre la première face d'appui (25) d'une contre-plaque (P1) d'un type donné et la plaque de tête (21), et des moyens de liaison démontable entre la plaque de tête (21) et chaque contre-plaque (P1) d'un type donné pour assurer l'étanchéité entre- elles.
Patent CA-2451319-A1 (CA)
Title: Methods and apparatus for refrigerator compartment
Inventor: CHASTINE GARY LESTER
IPC: F25D17/06
Filed: 2003-11-27
Abstract: A refrigerator is provided. The refrigerator includes a refrigeration compartment, a freezer compartment, and a third compartment controllable in both a refrigeration mode and a freezer mode.
Patent CA-2455372-A1 (CA)
Title: Water heater
Inventor: RYOO YOUNG
IPC: F23L9/00
Filed: 2004-01-20
Abstract: A water heater which includes a heat exchanger having a first passage and a second passage connected with the first passage, a gas burner mounted within the first passage, a push blower having an outlet connected with the gas burner for forcing air into the gas burner, and a water reservoir mounted surrounding the heat exchanger, whereby when the gas burner is turned on, the push blower will be turned on to force air into the gas burner thereby forcing combustion air generated from fire of the gas burner to move along the first passage and meanwhile the pull blower will be turned on to extract the hot air out of the second passage.
Patent CA-2456511-A1 (CA)
Inventor: MELCHING ACHIM
IPC: C12M1/00
Filed: 2004-01-30
Abstract: The invention concerns a climatic cabinet with specimen storage places and a transporting device and a monitoring device for specimen slides. The invention also concerns a device and a method for the monitoring of a climatic cabinet. The monitoring device is designed, with respect to its form and outside dimensions, so that it can be transported by the transporting system and can be laid on one of the specimen storage places and can be removed from a specimen storage place. That has the advantage that the monitoring device can be moved to any place with the already present transporting device, wherein not only individual specimen slides, but also specimen slide cassettes can be taken to their storage places and monitored, as well as stationary and movable storage devices in a position at rest and in operation, such as cassette carrier carousels, and parts of the transporting device itself. Another advantage is to be found in the fact that the filling of the climatic cabinet can take place by means of specimen slide cassettes, instead of an individual filling, and subsequently, a simple identification of the introduced specimen slides can take place. A preferred further refinement of the invention consists in a specimen storage place for the storage of the monitoring device being affixed to the outside of the climatic cabinet, which increases the service life and functioning reliability, since the monitoring device is not constantly exposed to the climate in the climatic cabinet, and furthermore, facilitates maintenance.
Patent CA-2458009-A1 (CA)
Inventor: SEBTI SAID
IPC: A61P29/00
Filed: 2002-08-23
Abstract: The present invention relates to piperazinone compounds, pharmaceutical compositions containing those compounds and methods of treating tumors and cancer, among other disease states and conditions in mammalian patients, especially including humans. The compounds according to the structure:   (see formula I) or (see formula II).
Patent CA-2459352-A1 (CA)
Title: Method and device for control by consumers over personal data
Inventor: BINDER PHILIP A
IPC: G06Q20/34
Filed: 2002-09-06
Abstract: A method for locking (430) and unlocking (440, 460) access to personal data (470).
Patent CA-2460148-A1 (CA)
Title: Buffer-effect dispersants for paint bases and compositions
Inventor: SUAU JEAN-MARC
IPC: C09D7/45
Filed: 2002-09-12
Abstract: The invention concerns the use, as buffer dispersant of compositions and bases for aqueous paints and paint-like pigment compositions in aqueous phase, of the combination of a partly or completely neutralized water-soluble dispersant homopolymer of acrylic or methacrylic acid with at least another ethylenically unsaturated monomer, alone or mixed, with a compound having specific buffer properties. The invention also concerns the buffer dispersants and the compositions and bases for aqueous paints and paint-like pigment compositions in aqueous phase containing said dispersants.
Patent CA-2460854-A1 (CA)
Inventor: JANNETTA THOMAS J
IPC: F02K1/72
Filed: 2002-09-13
Abstract: L'invention concerne un inverseur de poussée (32) comprenant des capots avant et arrière (34, 36) adjacents axialement qui définissent une nacelle de soufflante destinée à entourer une soufflante (16) et un moteur central (14), une canalisation de soufflante (20) étant disposée entre la nacelle de soufflante et le moteur central. Le capot arrière (36) présente une face avant (42) et le capot avant (34) présente une face arrière (40) contiguës l'une à l'autre, de sorte qu'elles définissent une tuyère d'inverseur (44) qui converge radialement vers l'extérieur. Le capot arrière (36) peut être déplacé entre une position repliée dans laquelle la tuyère d'inverseur est fermée, et une position déployée dans laquelle la tuyère d'inverseur est ouverte pour évacuer l'air de la soufflante dans un sens avant permettant l'inversion de la poussée.
Patent CA-2461756-A1 (CA)
Inventor: PARK SEO-KYU
IPC: G06Q30/02
Filed: 2002-09-24
Abstract: A principal guaranteeing game system, gaming method using the same on the internet and a storage media. The principal guaranteeing system on the internet and a recording medium of the same make a user play a game during a period determined according to a purchase amount by giving a game point as much as the purchase amount of an item and award a certain amount of property based on a game point obtained in the game. In order to achieve the above objects, there are provided an operator server (12) which guides and purchase an item, a game server (14) for executing and processing a game, and a terminal (16) of each member.
Patent CA-2461978-A1 (CA)
Title: A toy building set
Inventor: HATTING JAN
IPC: A63H33/10
Filed: 2002-10-07
Abstract: A toy building set that comprises: a first type of toy building elements (1) that are configured with at least two pro-truding parts (4,4') provided with aligned transversal openings (5,5'), a second type of toy building elements (2) that are configured with at least one protruding part (7) provided with a transversal opening (8), and a pin (3). The at least one protruding part (7) on the second type of toy building elements is/are configured for being able to be positioned between the at least two protruding parts (4,4') on the first type of toy building elements (1), whereby the transversal openings (5,5',8) are caused to be aligned, and the pin is configured such that it can be mounted in the transversal openings (5, 5',8) for interconnection with the toy building elements (1, 2). The pin (3) is provided with at least one snap-engagement bead (11) at a distance (L) from the one end thereof, said distance corresponding essentially to the width (B) of a distally arranged, protruding part (4) on the first type of toy building elements (1).
Patent CA-2462189-A1 (CA)
Inventor: TSUJI MAKOTO
IPC: H01M4/86
Filed: 2002-10-23
Abstract: In a fuel cell comprising a laminate wherein an electrode structure is sandwiched by separators, the separator (20A) has a projection (21) contacti ng an electrode structure (10) with the contact angle between this projection (21) and electrode structure (10) set smaller than the contact angle of wate r with the surface of the separator (20A). Regardless of the surface property of the separator, a corner part formed between the separator projection and electrode structure which contact each other is so constituted that water is hard to reside or penetrate. Thus, the draining capability of a gas channel is enhanced to improve power generating performance.
Patent CA-2462789-A1 (CA)
Title: Transfert thermique a rendement eleve utilisant un jet d'impact asymetrique
Inventor: AYDORE SAVAS
IPC: F26B13/10
Filed: 2002-10-22
Abstract: L'invention concerne un procédé et un appareil permettant de précipiter un fluide sur une surface mobile. L'appareil (40) comporte une buse (50) en fente asymétrique ayant une ouverture (56) formée entre une paroi en amont (58) et une paroi en aval (59). La buse (50) est disposée généralement contiguë à la surface (26) sur laquelle le fluide doit être précipité pour former une distance d'impact entre chaque paroi de la buse et la surface. La distance d'impact (60) de la paroi en amont (58) est supérieure à la distance d'impact (62) de la paroi en aval (59) de manière qu'au moins une partie du fluide est distribuée par la buse (50) dans une direction opposée à la direction de la machine (MD).
Patent CA-2463745-A1 (CA)
Inventor: VILLARD SYLVIE
IPC: A61P37/02
Filed: 2002-10-17
Abstract: The use of peptidic and pseudopeptidic mimics of factor VIII (I) in medicines for the prevention and treatment of disorders due to the appearance of antibodies against endogenous or exogenous factor VIII or its derivatives, which may be recombinant or not, administered in cases of hemophilia A.  The use of peptidic and pseudopeptidic mimics of factor VIII of formula (I) in medicines for the prevention and treatment of disorders due to the appearance of antibodies against endogenous or exogenous factor VIII or its derivatives, which may be recombinant or not, administered in cases of hemophilia A.  (X1)n1-C-Xa-C-(X2)n2        (I) n1, n2 = 0 or 1; X1, X2 = an amino acid that may be natural or not; and Xa = a chain of 8 - 10 amino acids that may be natural or not. Independent claims are also included for the peptide sequences themselves.
Patent CA-2465518-A1 (CA)
Inventor: SUBACIUS DARIUS
IPC: H04B10/2519
Filed: 2002-10-23
Abstract: The present invention is directed to an integrated system for performing dispersion compensation on wavelength channels in WDM or DWDM transmissions.  The system includes a tunable integrated dispersion compensation module (10) that performs chromatic dispersion compensation on wavelength channels in WDM  or DWDM transmissions. The system includes a tunable integrated dispersion compensation module (10) that performs chromatic dispersion compensation and polarization mode dispersion compensation on each of the wavelength channels in the transmission. Feedback is used to adjust the tunable integrated dispersion compensation module (10) until receiver performance is optimized.
Patent CA-2466973-A1 (CA)
Inventor: GILBERT STEVEN RAY
IPC: A61F13/20
Filed: 2002-11-14
Abstract: L'invention concerne un tampon cataménial absorbant qui présente une surenveloppe non nuisible pouvant s'imprégner d'un liquide, qui aide à retenir un liquide sans adhérer de manière nuisible aux tissus. Ce tampon comprend un élément absorbant généralement allongé et une surenveloppe recouvrant sensiblement la surface extérieure dudit élément absorbant généralement allongé, ladite surenveloppe contenant un matériau fibreux non-tissé qui comporte une combinaison de fibres synthétiques et de fibres de rayonne, les proportions de fibres synthétiques par rapport aux fibres de rayonne étant comprises entre environ 90:10 et environ 30:70.
Patent CA-2469003-A1 (CA)
Title: Golf ball with temperature indicator
Inventor: KENNEDY THOMAS J III
IPC: A63B37/00
Filed: 2002-11-25
Abstract: A golf ball (2) having an integral means for sensing temperature whereby a golfer can readily determine if a golf ball is at the optimum temperature fo r play. For purposes of indicating temperature, the ball (2) incorporates a thermochromic section (6) that will change color or become transparent or translucent at a predetermined temperature. The thermochromic section (6) ma y be printed in such a manner to indicate the condition of the ball.
Patent CA-2470983-A1 (CA)
Inventor: BULLIS MICHAEL L
IPC: H01F27/04
Filed: 2004-06-14
Abstract: A transformer is formed by a housing having a main transformer compartment, a first compartment for the input terminals for the main power supply, a second compartment for the output terminals to supply the load and a third compartment for a manually operable switching unit, where each of the compartments is maintained separately from each of the others and each has a manually openable interlocked cover which can be opened to provide access to an interior of the respective compartment. The switch assembly has switch contacts mounted within a switch container located within the third compartment and a manually operable member mounted one on side wall located within the third compartment outside the switch container for moving the switch contacts between open and closed positions. The switch container has a transparent window in a wall thereof through which the contacts can be observed and an insulating liquid bath maintained separate from an insulating liquid bath for the transformer assembly.
Patent CA-2471390-A1 (CA)
Title: Position encoder
Inventor: KNIERIM DAVID L
IPC: G01D5/36
Filed: 2004-06-18
Abstract: An optical encoder that includes an optical grating and a quadrature optical encoder sensor that move relative to each other. The optical grating includes a first encoder bar and a plurality of second encoder bars, wherein the first encoder bar is optically configured to change an amplitude of an output of the quadrature optical encoder sensor.
Patent CA-2474898-A1 (CA)
Inventor: EVANS GLEN A
IPC: C12N15/10
Filed: 2003-01-29
Abstract: The invention is directed to the creation of a collection of recombination products between two or more nucleotide sequences. The nucleotide sequences can encode distinct amino acid sequences and the collection of recombination products can be expressed to obtain a corresponding collection of polypeptid e recombination products or variants. The amino acid sequences encoded by the two or more nucleotide sequences can correspond to polypeptides that are similar in function, but are encoded by dissimilar nucleotide sequences that cannot be recombined using traditional methods of recombination, which requi re a high degree of sequence similarity.
Patent CA-2478730-A1 (CA)
Inventor: BOTSTEIN DAVID
IPC: C07K16/30
Filed: 1999-12-02
Abstract: The invention concerns compositions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based upon the identification of genes that are amplified in the genome of tumer cells. Such gene amplification is expected to be associated with the overexpression of the gene product as compared to normal cells of the same tissue type and contribute to tumorigenesis. Accordingly, the proteins encoded by the amplified genes are believed to be useful targets for the diagnosis and/or treatment (including prevention) of certain cancers, and may act as predictors of the prognosis of tumor treatment. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2479446-A1 (CA)
Title: Correlation of the ratio of tp and dpd mrna expression levels in colorectal cancer with disease-free survival in 5-fu treated patients
Inventor: WERNER MARTIN
IPC: C12Q1/68
Filed: 2004-08-25
Abstract: The present invention is directed to a method for determining whether a patient suffering from cancer is susceptable to a treatment with a 5-Fluoro-Uracil analogon comprising a) determination of Thymidine Phosphorylase mRNA expression in a clinical sample, b) determination of Dihydropyrimindine Dehydrogenase mRNA expression in said clinical sample, and c) determination of the ratio of the value obtained in step a) and the value obtained in step b). If the ratio exceeds a certain cut off, susceptability to 5-FU and/or 5-FU analoga can be expected.
Patent CA-2479888-A1 (CA)
Title: New crystalline forms of (2s)-n-5-¬amino(imino)methyl|-2-thienylmethyl-1-(2r)-2-¬(carboxymethyl)amino|-3,3-diphenylpropanoyl-2-pyrrolidinecarboxamide nh2o
Inventor: PARK JAE-HYEON
IPC: A61P7/02
Filed: 2003-03-21
Abstract: The present invention relates to crystalline forms of (2S)-N-5- [amino(imino)methyl]-2-thienylmethyl-1-(2R)-2-[(carboxymethyl)amino]-3,3- diphenylpropanoyl-2-pyrrolidinecarboxamide nH2O.
Patent CA-2481602-A1 (CA)
Title: Pharmaceutical composition comprising arsenite for the treatment of malignancy
Inventor: YANG YONG JIN
IPC: A61K33/34
Filed: 2002-04-10
Abstract: The invention relates to a pharmaceutical composition for the treatment of a solid malignancy chosen from the group consisting of colon tumour, gastric tumour, mammary tumour, ovarian tumour, prostate tumour, and renal tumour, said composition comprising a salt of meta-arsenite (AsO2-) and a pharmaceutically acceptable auxiliary. The invention also relates to its use and to a method of treatment.
Patent CA-2482293-A1 (CA)
Inventor: TAKAHASHI SEIKI
IPC: G01N33/20
Filed: 2003-04-10
Abstract: Conventional methods of examining chromium-containing nickel-based alloys, such as Inconel 600 alloy, for chromium-deficient phases necessitate surface corrosion or cutting and hence are methods accompanied by destruction and contrary to the idea of nondestructive examination. The information obtainable with the methods has been limited to one concerning surface chromium-deficient phases. The method, which is for examining a chromium-containing nickel-based alloy for grain boundary corrosion based on thermal sensitization, comprises:  measuring the saturation magnetization Ms(Ti) of a test piece at each of temperatures distributed at the same interval throughout the range of from the minimum to the maximum Curie temperatures corresponding to the chromium concentrations in the chromium-deficient phase of the alloy; and quantitatively determining the average spatial distribution of the chromium-deficient phase of the test piece, i.e., the volumes for respective chromium concentrations of the chromium-deficient phase at around grain boundaries, using a given arithmetic expression.