baber/WOPTO huggingface dataset:
Patent FI-822316-A0 (FI)
Inventor: CHEKROUN ISAAC
IPC: C07D333/20
Filed: 1982-06-29
Abstract: The present invention provides a multistep process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl)-ethylamine intermediates of the general formula:-    <IMAGE>  (I)  in which R1, in the 2-, 3-, 4- or 5-position, is a hydrogen or halogen atom, a nitro, amino, cyano or carboxyl group, a linear or branched alkyl or alkoxy radical or a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, R2 is a hydrogen atom, a linear or branched alkyl radical or a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, and Ar is a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, when the aminoethyl radical is in the two position and the radical R1 is in the 4- or 5-position, the above intermediates can be converted into 4,5,6,7-tetrahydrothieno[3,2-c]pyridine derivatives according to a procedure set forth in U.S. Pat. No. 4,127,580. When the aminoethyl radical is in the 3-position and the radical R1 is in the 4- or 5-position, the above intermediates can be converted into 4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives according to a procedure set forth in U.S. Pat. No. 4,127,580. Both sets of tetrahydrothieno pyridine final products possess anti-inflammatory, vasodilator and blood platelet aggregation inhibition activity.
Patent FI-823420-A0 (FI)
Inventor: SAMEJIMA MASAYOSHI
IPC: B01J13/02
Filed: 1982-10-08
Abstract: Novel enteric microcapsules containing an active compound as a core material, the coating walls of which consist essentially of ethylcellulose and an enteric polymer material, and optionally a water-swellable polymer material being incorporated into the core material, and a process for the preparation thereof. The microcapsules can easily release the active compound in intestinal tract while protecting the core material sufficiently in stomach.
Patent FI-842419-A0 (FI)
Inventor: SEIDEL PETER-RUDOLF
IPC: C07D403/14
Filed: 1984-06-14
Abstract: The invention relates to substituted 2-pyrimidinyl-1-piperazine derivatives defined herein by formula (I), processes for their manufacture, compositions containing said substituted 2-pyrimidinyl-1-piperazine derivatives as active materials and the use of said compounds and compositions as agents effecting the central nervous system. Also included in the invention are intermediates of formula (VIII) for making the active formula (I) compounds.
Patent FI-860125-A0 (FI)
Inventor: BUNNING DONALD LEROY
IPC: C07C45/50
Filed: 1986-01-10
Abstract: In a primary process for hydroformylating olefins to form aldehydes in which a liquid or gas recycle step is conducted and a gaseous effluent is vented, the improvement which comprises employing the effluent as a reactant feed for a decoupled secondary liquid-or gas recycle hydroformylation process conducted conjointly therewith.
Patent FI-864559-A0 (FI)
Inventor: BALSCHMIDT PER
IPC: C07K14/575
Filed: 1986-11-10
Abstract: PCT No. PCT/DK86/00023 Sec. 371 Date Jan. 28, 1987 Sec. 102(e) Date Jan. 28, 1987 PCT Filed Mar. 14, 1986 PCT Pub. No. WO86/05497 PCT Pub. Date Sep. 25, 1986.Insulin derivatives in which one or more of the four amino acid residues of positions A4, A17, B13 and B21 comprise an uncharged side chain and pharmaceutical preparations containing these insulin derivatives.
Patent FI-865223-A0 (FI)
Inventor: ALEXANDROV MAXIM LEONIDOVICH
IPC: G01N21/45
Filed: 1986-12-19
Abstract: An interference polarization refractometer comprises a polarized emission source (1) and, located consecutively one after another along the emission path, a means for the light beam splitting into two orthogonally polarized light beams, a measuring cell (3), a reflector (4) with a plane reflecting surface, a half-wave plate (5), the second reflector (6) the reflecting surface of which is perpendicular to the reflecting surface of the first reflector, a means for space fusion of the light beams and a unit for measuring the path difference components of the elliptically polarized light. The reflectors (4 and 6) are rigidly interconnected whereas the means for splitting and the means for fusion of the orthogonally polarized light beams are constituted by a single plane-parallel crystal plate (2) the main cross-section of which is perpendicular to the reflecting surfaces of the both reflectors (4, 6).
Patent FI-882307-A0 (FI)
Inventor: MESENS JEAN
IPC: A61K9/18
Filed: 1988-05-17
Abstract: Compostions containing flunarizine as active ingredient and as carrier an appropriate surfactant, said surfactant preferably being a polyethoxylated fatty acid or alcohol or a polyethoxylated oil or fat (glyceride) and more in particular said polyethoxylated fatty acid, alcohol, oil or fat contains 5 to 100 and preferably 20 to 60 ethoxy units, and if desired, other adjuvants.
Patent FI-882456-A0 (FI)
Inventor: BOLLEN ALEX
IPC: C12N15/12
Filed: 1988-05-25
Abstract: The present invention provides recombinant DNA sequences comprising a sequence which codes for human proapolipoprotein A-I wherein part of the natural coding sequence has been replaced by a DNA fragment coding for the same amino acids but consisting of a different nucleotide sequence such as to reduce or prevent formation of hairpins, cloning and expression vectors containing these DNA sequences, cell cultures or microorganisms transformed with these expression vectors and processes using the same for the production of proapolipoprotein A-I.
Patent FI-884653-A0 (FI)
Inventor: THORBEK PIA
IPC: C07K1/00
Filed: 1988-10-11
Abstract: Dipeptides having the general formula      H-A-B-Y wherein A represents an optionally side-chain protected L- or D- alpha -amino acid or  omega -amino acid and B represents an optionally side-chain protected L- or D- alpha -aminocarboxylic acid which may be the same as or different from A, an L- or D-aminophosphonic acid or L- or D-aminosulfonic acid or the corresponding  omega -amino acids or salts and hydrates thereof, and Y is OH or a C-terminal blocking group, are prepared by reacting a substrate component, which is an amino acid derivative having the formula <CHEM> wherein A is as defined above, R<1> represents hydrogen, alkyl, aryl or aralkyl optionally substituted with inert substituents or an alpha -des-amino fragment of an amino acid, and R<2> and R<3> are the same or different and each represents hydrogen, alkyl, aryl or aralkyl optionally substituted with inert substituents, with a nucleophile component which when A = B may be formed in situ and is selected from     (a) L-amino acids having the formula        H-B-OH   (b) L-amino acid amides having the formula <CHEM> wherein B is an L-amino acid, and R<2> and R<3> have the above meaning, except that when R<2> represents hydrogen, R<3> may also represent hydroxy or amino   (c) L-amino acid esters having the formula        H-B-OR<4> wherein B is an L-amino acid, and R<4> represents alkyl, aryl or aralkyl, and (d) optionally acid group protected straight chain or branched amino phosphonic acids or amino sulfonic acids having the formula        NH2CxHzPO3H2 or NH2CxHzSO3H  wherein x is 1-6 and z is 2-12 in the presence of a serine or thiol carboxypeptidase from yeast or of animal, vegetable or other microbial origin, preferably CPD-Y from yeast in an aqueous solution or suspension having a pH value between 5 and 10.5 optionally containing an organic solvent and/or a salt, and then, if desired, cleaving a present side-chain protecting group or protective group Y and/or, if desired, converting the resulting dipeptide derivative to a salt or hydrate. The process allows for production of L,L-, LD-, DL- and DD-dipeptides without risk of racemization in a simple and economic manner.
Patent FI-901999-A0 (FI)
Inventor: HAUK KLAUS
IPC: B60Q1/42
Filed: 1990-04-20
Abstract: A switching device emits signals for direction indication, switching over from dipped headlights to full beam, the headlight flasher and the horn of a motor vehicle. For triggering the signals, it has a manually actuatable switching lever (10, 12) which is mounted so as to be rotatable and tiltable in a switching console (14). A tension spring (26), one end of which engages directly or indirectly on the switching lever (10, 12) and the other end of which engages directly or indirectly on the switching console (14), extends in the switching lever axis (28). The tension spring (26) is hooked into a pin (34), which is connected to the switching lever (10, 12) and at the same time fulfils the function of a tilt axis, and of a rotary stop and ensures a minimum spacing between switching lever (10, 12) and switching console (14). The horn function is implemented by means of a push-rod (162) which is mounted in the switching lever (10, 12) and on which a switching piece (178) of a switching element is mounted. The flashing function is carried out by means of two microswitches (20, 24) mounted off-centre on the switching console (14), it being possible to actuate said microswitches by rotating the switching lever (10, 12) and overcoming catch positions. The switching over between dipped headlights and full beam occurs by tilting the switching lever (10, 12) between catch positions (61) of a switching link (18) in which the central microswitch (22) is actuated in all switching positions by means of a component (130) which engages through the switching console (14). The headlight flasher facility is triggered by contact pieces (182, 184) which are mounted at the lower end (148) of the switching lever (10, 12) or on the switching link (18) and can be brought into contact by tilting the switching lever (10, 12) into a key position defined by the switching link (18). <IMAGE>
Patent FI-905090-A0 (FI)
Inventor: GOETTSCHE REIMER
IPC: B27K3/52
Filed: 1990-10-16
Abstract: Wood preservatives which contain a mixture of an N-organyldiazeniumdioxy-metal salt and a complex-forming polymeric nitrogen compound are used for preserving wood.
Patent FI-913091-A0 (FI)
Inventor: MUELLER WALTER
IPC: B29C45/24
Filed: 1991-06-25
Abstract: PCT No. PCT/DE90/00663 Sec. 371 Date Aug. 16, 1991 Sec. 102(e) Date Aug. 16, 1991 PCT Filed Aug. 30, 1990 PCT Pub. No. WO91/06413 PCT Pub. Date May 16, 1991.A nozzle for injecting molten plastic includes a housing having an inlet and an outlet. Wires embedded in the housing serve to heat the housing. The housing defines a chamber, and a strainer is disposed in the chamber between first and second guides which are respectively located adjacent to the inlet and the outlet. The strainer and the guides divide the chamber into an outer compartment which surrounds the strainer and an inner compartment within the strainer. A rod extends through the inner compartment and carries first and second pistons which are slidably supported by the first and second guides, respectively, so that the rod can be moved between two terminal positions. Each of the pistons is provided with an axial blind bore and several radial bores which radiate from the associated blind bore. In a first terminal position of the rod, molten plastic from the inlet flows successively through the bores in the first piston, the inner compartment the strainer, the outer compartment and the outlet leaving contaminants in the inner compartment. In the second terminal position of the rod, molten plastic from the inlet flows successively through the bores in the first piston, the passages in the first guide, the outer compartment the strainer, the inner compartment, the bores in the second piston and a tube in register with the axial bore in such piston to flush the contaminants from the inner compartment.
Patent FI-923838-A0 (FI)
Inventor: LARSEN HANS KURT
IPC: B65B3/10
Filed: 1992-08-27
Abstract: A filler for dosing a flowable product comprising a rigid casing (11) having an inlet (14) and an outlet opening (15) within which is an elastic hose (16) whose ends are connected to the openings, means for generating super- or sub-atmospheric pressure in the space between the casing and the hose, and two elastic rings (19,20) each encircling the hose adjacent and opening adapted to enable simultaneous expansion and contraction of the inlet and outlet rings respectively at the generated pressure. <IMAGE>
Patent FI-925236-A0 (FI)
Inventor: TALARMO REINO
IPC: H04W68/00
Filed: 1992-11-18
Abstract: PCT No. PCT/FI93/00486 Sec. 371 Date Jun. 29, 1995 Sec. 102(e) Date Jun. 29, 1995 PCT Filed Nov. 17, 1993 PCT Pub. No. WO94/11997 PCT Pub. Date May 26, 1994A method for establishing a connection between a first communication device, connected to a communication network and having at least one identity, and one or several second communication devices, connected to the communication network and located in a limited location (i.e., paging) area, each of them having at least one identity. In order that the user of the system may define the location area dynamically, the first communication device sends to the communication network a message containing an identification of the location area and the identity of one or several second communication devices and the communication network calls at least one subscriber device provided with the identity only in the location area defined by the location area identification.
Patent FI-930241-A0 (FI)
Inventor: HOLT GRENVILLE
IPC: C10N30/10
Filed: 1993-01-21
Abstract: This invention relates to a lubricating oil composition which has a major proportion of a biodegradable base fluid which is a blend of (a) at least one ester of isotridecyl alcohol and a mono-, di or polycarboxylic acid, and (b) at least one hydrocarbon oil which has no more than 10%w/w of aromatic hydrocarbons, the rest being aliphatic. The proportion of (a) in the blend is from 25-55%w/w. The biodegradability of the base fluid renders the composition more environmentally friendly.
Patent FI-935793-A0 (FI)
Inventor: BIENSTEIN CRISTEL
IPC: A61F13/15
Filed: 1993-12-22
Abstract: A disposable diaper (1) has a liquid-tight clothing protecting foil (3), a liquid-permeable nonwoven covering (4) and an absorbent body (5) arranged between the clothing protecting foil (3) and the nonwoven covering (4), as well as sealing strips (16) that form the outer contour of the diaper. In order to help incontinent persons to learn the use of the toilets, hydrophilic side tabs (11) linked to the liquid-permeable nonwoven covering (4) are arranged on the outer contour of the sealing strips (16) so as to project at least partially sideways.
Patent FI-950326-A0 (FI)
Inventor: ZETTER CLAES
IPC: D21H17/62
Filed: 1995-01-25
Abstract: The present invention relates to a method of improving the water repellency of paper in papermaking by virtue of adding prior to web formation to the pulp slurry such a sizing dispersion that contains at least a ketene dimer compound as a hydrophobic sizing agent, and further contains water-soluble colloidal polymer in an amount which is at least 100 % by weight of the hydrophobic sizing agent. The invention is particularly applicable for improving the water repellency of paper containing calcium carbonate as the filler.
Patent FI-953412-A0 (FI)
Inventor: VOLPP STEVEN WAYNE
IPC: G10D13/02
Filed: 1995-07-12
Abstract: A drum having improved acoustic characteristics comprises a rigid annular bridge at one or both ends of a thin resonant annular shell attached to the bridges. A drum head is mounted on the bridge by a tension mechanism attached only to the bridge, and the drum is mounted on a drum stand by mounting hardware attached only to the bridge, leaving the shell free of load bearing and tensive and compressive forces and making the shell resonate more effectively. The bridge is machined from a solid block of wood formed of horizontal laminations. A microphone can be mounted on the inside of the bridge, with electrical leads exiting the drum through the mounting hardware. A snare drum having a thick body instead of a resonant shell is machined in the same way and has internal head tension members that make it possible to have a thicker body.
Patent FI-960482-A0 (FI)
Inventor: CASTELHANO L ARLINDO
IPC: C07F9/645
Filed: 1996-02-02
Abstract: Compounds of formula (I), wherein the dashed lines denote optional double bonds; and when n is 1, 2 or 3; m is 3 or 4; A is -CH2-; R<1> is a) -CH2-R<4> where R<4> is mercapto, acetylthio, carboxy, hydroxyaminocarbonyl, N-hydroxyformamidomethyl, alkoxycarbonyl, aryloxycarbonyl, aralcoxycarbonyl, benzyloxyaminocarbonyl, or (i), where R<6> is optionally substituted aryl, wherein the aryl group is quinol-2-yl, naphth-1-yl, naphth-2-yl, pyridyl or phenyl; b) -CH(R<7>)-R<8> where R<7> is alkyl, hydroxy, amino, aminomethyl, alkylsulphonylamidomethyl, aralkylsulphonylamidomethyl, alkoxycarbonyl, alkoxycarbonylaminomethyl, alkylaminocarbonylamidomethyl, benzoxazoleaminomethyl, aminocarbonyl, or carboxy; and R<8> is carboxy, hydroxyaminocarbonyl, alkoxycarbonyl or aralkoxycarbonyl; c) -NH-CH(R<9>) -R<10> where R<9> is hydrogen, alkyl or aralkyl, and R<10> is carboxy, alkoxycarbonyl, aralkoxycarbonyl, phosphonyl or dialkylphosphonyl; R<2> is alkyl, cycloalkyl, cycloalkylalkyl or aralkyl; and R<3> is hydrogen, halo, alkyl or alkoxy; or when n is 2 or 3; m is 3 or 4; A is -N(R<11>)-, where R<11> is hydrogen or alkyl; and R<1>, R<2> and R<3> are as defined above; or when n is 0; m is 4, 5 or 6; A is -CH(R<12>)-, where R<12> is carboxy, alkoxycarbonyl or optionally substituted carbamoyl; and R<1>, R<2> and R<3> are as defined above; as single stereoisomers or mixtures thereof; or pharmaceutically acceptable salts thereof; are useful in inhibiting matrix metalloprotease activity in mammals.
Patent FI-962799-A0 (FI)
Inventor: BEHR JEAN-PAUL
IPC: A61P35/00
Filed: 1996-07-09
Abstract: The present invention relates to compositions comprising at least one nucleic acid and one lipopolyamine, and their utilisation in gene therapy, particularly for the transfert in vivo of nucleic acids.
Patent FI-990586-A0 (FI)
Inventor: SEVANTO JARKKO
IPC: H04L12/66
Filed: 1999-03-16
Abstract: A method is provided for transmitting multimedia-related information between a first device and a second device coupled to a packet-switched data transmission network. A first protocol stack (201, 202, 203, 204, 205, 206, 207) is defined for the first device and a second protocol stack (251, 252, 253, 254, 255, 256) is defined for the second device. The protocol stacks consist of layers and serve the arranging of the mutual exchange of information between the first device and the second device. An octet stream protocol layer (206, 255) is defined for the transmission of unstructured octet streams as a certain layer in the first protocol stack and a certain layer in the second protocol stack. A multimedia messaging transport protocol layer (207, 256) is also defined as a certain layer above the octet stream protocol layer (206, 255) in the first and second protocol stacks. Multimedia-related information is exchanged between the multimedia messaging transport protocol layer (207) in the first device and the multimedia messaging transport protocol layer (256) in the second device through the use of the octet stream protocol layer (206, 255) as well as other lower layers in the first and second protocol stacks.
Patent IL-60531-A0 (IL)
Title: 5-phenyl-purines,their preparation and pharmaceutical compositions containing them
IPC: A61P9/04
Filed: 1980-07-09
Abstract: This invention is directed to 8-phenyl-purines of general formula <IMAGE>   wherein R1 is a hydrogen or halogen atom; an alkoxy group optionally substituted by alkylmercapto, alkylsulfinyl or alkylsulfonyl group; or an alkylmercapto, alkylsulfinyl or alkylsulfonyl group, whereby each alkyl moiety may contain from 1 to 3 carbon atoms, and R2 is an alkoxy group with from 1 to 3 carbon atoms, and their physiologically compatible acid addition salts. The compounds exhibit valuable pharmacological properties, particularly positive inotropic activity.
Patent IL-64272-A0 (IL)
Title: Preparation of monoalkyl ethers of hydroxyphenols
IPC: C07C67/00
Filed: 1981-11-12
Abstract: A process for the preparation of a monoalkyl ether of a hydroxyphenol of the formula   <IMAGE>   in which Z each independently is hydrogen or a substituent which is stable under the reaction conditions, R is lower alkyl, and n is 1, 2, 3 or 4, comprising reacting a hydroxyphenol of the formula   <IMAGE>  with an alkyl halide, alkyl sulphonate or aryl sulphonate alkylating agent of the formula R-X in which X is a halogen atom, or an alkylsulphonyloxy or arylsulphonyloxy radical, at a temperature from about 130 DEG  C. to 200 DEG  C. and in the presence of an alkali metal base or alkaline earth metal base and of a diluent comprising a polyhydroxyalkyl ether having at least one OH group. Advantageously the base is sodium carbonate, sodium bicarbonate, potassium carbonate or potassium bicarbonate, the hydroxyphenol is pyrocatechol, the alkylating agent is isopropyl chloride, isopropyl C1-4-alkyl-1-sulphonate, isopropyl benzenesulphonate or isopropyl tolyenesulphonate, and the polyhydroxyalkyl ether is glycol monomethyl ether, about 1.5 to 1.8 mols of alkylating agent and about 1 to 2 mols of the base being employed per mol of pyrocatechol, about 1.5 to 2.5 parts by weight of the glycol monomethyl ether being employed per part by weight of pyrocatechol, the reaction being effected in an inert atmosphere under elevated pressure.
Patent IL-72844-A0 (IL)
Title: Switching fiber optic amplifier
IPC: G01C19/72
Filed: 1984-09-03
Abstract: A fiber optic amplifier utilizes a crystal fiber of laser material to bidirectionally amplify light signals. This amplifier permits the application of both pumping illumination and the signal to be amplified to the end of the crystal fiber to avoid the disadvantages inherent in side pumping this fiber. End pumping is accomplished by taking advantage of the slow spontaneous fluorescence of the laser crystal to sequentially apply the pumping illumination and then the signal to be amplified to the crystal. This sequential application of signals is made possible through the use of a switchable coupler which allows light to be selectively coupled from either of a pair of input optical fibers to a single output optical fiber which is coupled to the crystal fiber. The pumping illumination is initially supplied to the crystal fiber to invert the ions within the crystal. Once these ions are inverted, the coupler is switched to permit the application of the signal to be amplified to the crystal, and the application of pumping illumination is temporarily discontinued. The signal to be amplified propagates through the crystal to stimulate emission of coherent light from the laser material resulting in amplification of the signal. When this amplification process is complete, pumping illumination is again applied through the switch to the crystal fiber.
Patent IL-77186-A0 (IL)
Title: Pharmaceutical insulin composition
IPC: A61K38/00
Filed: 1985-11-29
Abstract: A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and usually, a carrier. The absorption promoter is capable of enhancing absorption of the active ingredient from the intestine into the bloodstream. The capsule is coated with a film forming composition, which film is sufficiently insoluble at a pH below 7 as to be capable of protecting the capsule and its contents from the digestive juices until the capsule reaches a region below the upper part of the intestine, whereupon the coating and capsule are capable of eroding or dissolving to release the active ingredient for absorption into the bloodstream.
Patent IL-92799-A0 (IL)
Title: Benzimidazole derivatives with gastric acid inhibition and process for its preparation
IPC: A61K31/415
Filed: 1989-12-19
Abstract: The novel compound 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient, and the use of the compound in medicine.