Patent SG-11201408782T-A (SG)
Title: Drug infusion with pressure sensing and non-continuous flow with indentification of and injection into fluid-filled anatomic spaces
Inventor: HOCHMAN MARK N
IPC: A61M5/00
Filed: 2013-06-11
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 9 January 2014 (09.01.2014) WIPOIPCT (10) International Publication Number WO 2014/007949 A1 (51) International Patent Classification: A61M5/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/045142 11 June 2013 (11.06.2013) English English (30) Priority Data: 13/540,880 3 July 2012 (03.07.2012) (71) Applicant: MILLESTONE SCIENTIFIC, INC. [US/US]; 220 South Orange Avenue, Suite 102, Living­ ston, NJ 07039 (US). (72) Inventor: HOCHMAN, Mark, N.; 26 Meadow Woods Road, Great Neck, NJ 11020 (US). (74) Agent: MICHALOS, Peter, C.; Notaro, Michalos & Zac- caria P.C., 100 Dutch Hill Road, Orangeburg, NY 10962 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Ug (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: DRUG INFUSION WITH PRESSURE SENSING AND NON-CONTINUOUS FLOW WITH INDENTIFICATION OF AND INJECTION INTO FLUID-FILLED ANATOMIC SPACES FIG. 1 70 72 0\ •t o\ l> o o o CJ O & (57) Abstract: An automatic injection apparatus uses non-continuous fluid-flow of drugs to identify an intended injection site and includes drive mechanism, sensor a a and a controller for establishing fluid flow and pressure and preventing fluid flow until the pressure drops below a predetermined threshold. The pressure threshold is determined based on an internal pressure generated dur­ ing an injection and more fluid will not flow until drops below predetermined pressure. it a An injection is performed to establish an initial pressure threshhold and then to stop the fluid flow into patient a until the pressure drops below predetermined pressure a which allows fluid flow resume, thus identifying fluid filled to a tissue space. The initial pressure threshold used is as a control para­ meter to a microprocessor below which controls the rate of injection. Fluid flows below certain pressures are also used to identify a specific location within the body during injections.