Patent SG-11201908061S-A (SG)
Title: Device for delivery of powdered hemostatic agents
Inventor: HOLSCHER RUSSEL L
IPC: A61L15/32
Filed: 2018-03-07
Abstract: LayerNon-dissolving Films are sealed around the perimeter of the pad, sealing in the powder i=> Applied to bleed site (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 13 September 2018 (13.09.2018) WIP0 I PCT omit Oil 10110111 How oimIE (10) International Publication Number WO 2018/165275 Al (51) International Patent Classification: A61L 15/32 (2006.01) A61L 15/62 (2006.01) A61L 15/60 (2006.01) (21) International Application Number: PCT/US2018/021313 (22) International Filing Date: 07 March 2018 (07.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/468,797 08 March 2017 (08.03.2017) US (71) Applicants: BAXTER INTERNATIONAL INC. [US/US]; One Baxter Parkway, Deerfield, Illinois 60015 (US). BAXTER HEALTHCARE SA [CH/CH]; Thur- gauerstrasse 130, 8152 Glattpark (Opfikon) (CH). (72) Inventors: HOLSCHER, Russel L.; 886 Spruce Street, Winnetka, Illinois 60093 (US). SANDERS, Paul Jeffer- ey; 5240 Oakton Lane, Greendale, Wisconsin 53129 (US). FULGHUM, Timothy Michael; 32137 North Rockwell Drive, Lakemoor, Illinois 60073 (US). BARRY, John Joseph Anthony; 723 Greenwood Road, Northbrook, Illi- nois 60062 (US). (74) Agent: PLUMMER, Kelly A.; K&L Gates LLP, c/o For- eign Patents, P.O. Box 1135, Chicago, Illinois 60690-1135 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (54) Title: DEVICE FOR DELIVERY OF POWDERED HEMOSTATIC AGENTS Figure 1 Layer 2 Layer 1 Layer 1 dissolves/degrades, depositing the hemostatic. Layer 3 dissolves/degrades kt) N kt) a second layer including a powdered hemostatic agent provided on the first layer, and a third layer including at least one of gauze, . oxidized cellulose, or collagen provided on the second layer, wherein the first layer and the third layer encapsulate the second layer and 0 the hemostatic agent comprises one of fibrinogen, thrombin, fibrin monomers, or the combination of thrombin and gelatin. C [Continued on next page] (57) : The disclosure provides a multilayered hemostatic device including a first layer including carboxymethyl cellulose, WO 2018/165275 Al MIDEDIMOMMIDIREIDI311111111111111111101111111111111111111111111111 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(U)) Published: — with international search report (Art. 21(3))