baber/WOPTO huggingface dataset:
Patent JP-2010145153-A (JP)
Title: Rotation angle sensor
Inventor: SAKAI MASAHIKO
IPC: G01D5/245
Filed: 2008-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To suppress accuracy deterioration caused by a leakage flux by a comparatively simple structure.  <P>SOLUTION: A plurality of slits arranged at equal angle intervals respectively in the circumferential direction are provided on a rotor 20 of a nonmagnetic conductor, and on a stator 30 of a nonmagnetic conductor arranged on the outer circumferential side of the rotor 20, and a magnetic flux generated by a driving coil 40 provided on the outer circumferential side of the stator 30 is detected by a detection coil 50 provided on the inner circumferential side of the rotor 20. In a measuring circuit 60, a phase change of the magnetic flux detected by the detection coil 50 is measured, and outputted as a detection signal.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010147886-A (JP)
Title: Sub-reflector, radio wave power supply part, and parabolic antenna
Inventor: SHIKAYAMA TOSHIKI
IPC: H01Q19/19
Filed: 2008-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a sub-reflector which is superior in fitting operability, quality stability and mass productivity, a radio wave power supply part including the sub-reflector and a parabolic antenna including the radio wave power supply part.  <P>SOLUTION: The sub-reflector includes a reflector formed of a thin plate and reflecting or emitting a radio wave, a positioning means of determining a position of attachment to the radio wave power supply part, a crimping fixation means of fixing the attachment to the radio wave power supply part. The position of the attachment is determined by the positioning means provided outside the reflector, and the crimping fixation means provided outside the reflector is crimped to the radio wave power supply part, so that the sub-reflector fixes the attachment to the radio wave power supply part.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2009149893-A (JP)
Title: Method for removing iron residue and rhodium-and ruthenium-containing catalyst residue from nitrile rubber optionally hydrogenated
Inventor: ONG CHRISTOPHER
IPC: B01J31/24
Filed: 2008-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for removing an iron residue and a rhodium- and ruthenium-containing catalyst residue from an optionally hydrogenated nitrile rubber.  <P>SOLUTION: The method for removing the iron residue and the rhodium- and/or ruthenium-containing catalyst residue from a solution of the optionally hydrogenated nitrile rubber containing such an iron residue and the rhodium- and/or ruthenium-containing residue, namely, the method in which such a solution is brought into contact with the specific functionalized ion exchange resin is provided.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009173891-A (JP)
Title: Method for producing chloroprene rubber composition, chloroprene rubber composition, and adhesive using the same
Inventor: OTSUKA HIDEHITO
IPC: C08F36/18
Filed: 2008-12-22
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for producing a chloroprene rubber composition from which solvent type adhesives excellent in adhesive physical properties and layer separation stability can be produced and which itself is excellent in storage stability.  <P>SOLUTION: In the method for producing the chloroprene rubber composition, chloroprene is emulsion-polymerized in the presence of a rosin acid salt, a polymerization inhibitor is added therein to stop the emulsion polymerization after the polymerization degree of the monomers reaches 50 to 90%, and at least one of specific ethylenic unsaturated sulfonic acid compounds is added to the polymerization-finished polychloroprene latex.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2010148313-A (JP)
Title: Motor with reduction gear
Inventor: TOKISAKI TEPPEI
IPC: H02K5/22
Filed: 2008-12-22
Abstract: <P>PROBLEM TO BE SOLVED: To provide a wiper motor which enables easy change of the direction of a connector.  <P>SOLUTION: A fixed terminal member 33 of the connector 32 is wired to a fitting part 31 formed in a substrate case. A holder 34 of the connector 32 is supported in the fitting part 31 so as to be freely rotated so that its position regulation is made downward, horizontally and upward. A movable terminal member 41 is insert-molded to the holder 34. One end part of the movable terminal member 41 is turnably connected by a hinge 42 at a projecting side end part of the fixed terminal member 33. A slit 43 is formed in the holder 34 so as to avoid interference of the fixed terminal member 33 with the holder 34, when the holder 34 rotates in the fitting part 31.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010143198-A (JP)
Title: Injection molding apparatus
Inventor: MIZUTANI TOSHIHIKO
IPC: B29C45/64
Filed: 2008-12-22
Abstract: <P>PROBLEM TO BE SOLVED: To constitute a vertical injection molding machine more compactly than the machine having a mold releasing mechanism outside the both metallic molds 20, 21.  <P>SOLUTION: In the mold releasing mechanism, a molten resin charged in a cavity formed between the metallic molds solidifies in a state where both metallic molds 20, 21 come into contact with each other to form a molding. At this time, both metallic molds 20, 21 are bonded because of bonding of the molding in the cavity or the like and it is necessary to provide the mold releasing mechanism for separating both metallic molds 20, 21 besides a usual lifting mechanism. In this embodiment, a hydraulic cylinder 40 is provided by being incorporated in a lower metallic mold 20 as the mold releasing mechanism. The piston 44 of the hydraulic cylinder 40 pressurizes the lower metallic mold 20 downward by separation force F with rise of pressure P in a hydraulic chamber 45 to carry out mold releasing. Here, each hydraulic cylinder 40 is provided at a first to forth provision holes in an upper metallic mold 21.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010126430-A (JP)
Title: Translucent yag polycrystal body and method of manufacturing the same
Inventor: YOSHIDA HIDEHIRO
IPC: C04B35/44
Filed: 2008-11-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a translucent ceramic comprising a crystal having a garnet structure synthesized from Y<SB>2</SB>O<SB>3</SB>(yttria) and Al<SB>2</SB>O<SB>3</SB>(alumina), wherein the addition of any form of metal elements except Y and Al is made needless by controlling the composition ratio of Y<SB>2</SB>O<SB>3</SB>and Al<SB>2</SB>O<SB>3</SB>to be raw materials.  <P>SOLUTION: High purity Y<SB>2</SB>O<SB>3</SB>powder and high purity Al<SB>2</SB>O<SB>3</SB>powder are used as starting raw materials and weighed to have a ratio of 35.5-37.5% Y<SB>2</SB>O<SB>3</SB>and 64.5-62.5% Al<SB>2</SB>O<SB>3</SB>and uniformly mixed by ball-mill mixing. After molded under cold hydrostatic pressure of 100-400 MPa, the mixture is sintered at ≥1,700°C for 2-16 hr under evacuated pressure. The resultant sintered body is a polycrystal body comprising YAG crystal single phase having about 100% relative density and has translucency in a wavelength region of 400-2,000 nm. The material is suitably used as a heat resistant optical window, a laser host material, an optical lens material and a plasma resistant optical window.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010151516-A (JP)
Title: Centrifuge apparatus
Inventor: YOSHIDA KAZUHIRO
IPC: B04B5/02
Filed: 2008-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To effectively remove fat contents included in a cell suspension, while improving recovery of cells derived from tissues.  <P>SOLUTION: The centrifuge apparatus 1 includes a cylindrical closed-end centrifugal vessel 6 for storing a cell suspension obtained by mixing tissues and digestive enzymes; a rotary arm 3 for rockably supporting the centrifuge vessel 6 around a prescribed rocking axis 5; a rotary drive means 4 for performing centrifugal motion of the rotary arm 3 about a rotary axis 2 separated from the rocking axis 5; a suction means 7, having a suction port 10a that is open near a sidewall, inside the centrifugal vessel 6 at a halfway position in the longitudinal direction of the centrifuge vessel 6, and a rocking angle adjustment means 8 for adjusting the rocking angle of the centrifuge vessel 6 so that the position of a liquid level, when the centrifuge vessel 6 is subjected to centrifugal motion, coincides with the suction port 10a.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010151558-A (JP)
Title: Tape measure
Inventor: HARA TERUTAKE
IPC: G01B3/10
Filed: 2008-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a tape measure which prevents a name plate stuck onto a cover fitted to the case of the tape measure from coming off and which can be used safely over a long period of time, without deteriorating the impulse protection function of the cover, and similar to conventional types for the name plate also, displays a name plate which is distinctive and colorfully designed and is affixed so as to enable persons to recognize the name of the company, at a glance, given the commodity and the name of the commodity.  <P>SOLUTION: The tape measure includes the case 1 having a measuring tape inside; and the cover 3, fitted in such a way as to surround the case and made of elastic material, and at least a part of the cover 3 on the side which does not have a belt clip at the position of a side surface 1a of the case is made up of a material that possesses translucency.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010013726-A (JP)
Title: Copper powder for electroconductive paste, and electroconductive paste
Inventor: ODA AKIHIRO
IPC: B22F1/10
Filed: 2008-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a copper powder which does not impair both of oxidation resistance and a balance of electroconductivity though the particle size is very small; a copper powder for an electroconductive paste, of which the shape and the particle size is also small and which contains little oxygen; and the electroconductive paste.  <P>SOLUTION: The copper powder for the electroconductive paste contains 0.1 to 10 atm% Si (silicon) inside the particle. The copper powder contains 0.01 to 0.3 atm% P (phosphorus) inside the particle.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010150609-A (JP)
Title: Etchant and etching method
Inventor: NOZAKI TAKASHI
IPC: C23F1/38
Filed: 2008-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide an etchant which can reliably keep an etching rate at a level suitable for productivity while suppressing an amount of side etching, and to provide an etching method therefor.  <P>SOLUTION: The etchant is directed for etching an titanium-tungsten-based alloy film on a semiconductor substrate while using gold as an etching resist, and includes hydrogen peroxide, a chelating agent, an alkali hydroxide and an iodine compound. The etching method using the etchant is adopted.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010153647-A (JP)
Title: Organic electroluminescence display
Inventor: YAMASHITA KOICHI
IPC: H01L51/50
Filed: 2008-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide an organic electroluminescence display that can increase an injection amount of electrons to an electron transporting layer.  <P>SOLUTION: The organic electroluminescence display has a luminescent layer EMT, a hole transporting layer HT, an electronic transporting layer ET, and an electron injection layer EI. The electron injection layer EI is arranged between a cathode and the electronic transporting layer ET, and includes lithium and a material for transferring lithium ion.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010148781-A (JP)
Title: Game device and method of control of game
Inventor: HORIE SATOSHI
IPC: A63F13/213
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide a game device that facilitates device miniaturization and facilitates execution of a player-versus-player game scene through simulation, based on operation input on the part of a player.  <P>SOLUTION: The game device comprises a field panel 9, which simulates a sports competition field, a card holding stand 10, which is positioned above the field panel 9, in a location that denotes a position of a competitor in the sports competition, and in a state that holds up a card 11, a card information reading means, which reads a card information that is recorded upon the card 11 that is held upon the card holding stand 10, and a game execution control means, which controls an execution of a game. The game execution control means further comprises a means that controls a player-versus-player game scene that is displayed upon a touch panel 6 in accordance with the card information that the card information reading means reads, in order that an execution by simulation in accordance with an operation on the part of a player runs for a preset predetermined number of iterations.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010155199-A (JP)
Title: Method of manufacturing catalyst-carrying filter
Inventor: NAKAJIMA KEIJI
IPC: B01J37/08
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method of manufacturing a catalyst-carrying filter which can easily manufacture the catalyst-carrying filter.  <P>SOLUTION: A porous ceramic substrate is prepared as a carrier. A mixture of polyvinyl alcohol forming a physical gel by itself and polyallylamine having a dissociative functional group in a repeat unit is prepared as a polymer mixture. A layer of the polymer mixture having adsorbed metal ions or metal complex ions containing Pt and Ni serving as a catalyst is formed on the surface of the carrier. The polymer mixture is burned in the layer of the polymer mixture having adsorbed thereon the metal ions or the metal complex ions. In such a way, the catalyst-carrying filter carrying the metals, serving as a catalyst, on the carrier is manufactured.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010157893-A (JP)
Title: Solid-state imaging apparatus, method of driving the same, and imaging system
Inventor: SUGIYAMA HIDEICHIRO
IPC: H04N5/335
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide a solid-state imaging apparatus, capable of reducing color mixture and sensitivity nonuniformity, while suppressing the generation of dark current, and to provide a method of driving the same and an imaging system.  <P>SOLUTION: The solid-state imaging apparatus has a plurality of pixels, wherein each pixel includes: a photoelectric converter that converts incoming light into an electric charge; an accumulating part that accumulates the electric charge converted by the photoelectric converter; a first transfer part that transfers the electric charge converted by the photoelectric converter to the accumulating part; a second transfer part that transfers the electric charge accumulated in the accumulating part to a floating diffusion region; and an amplifier that amplifies the electric charge in the floating diffusion region. The first transfer part transfers the electric charge converted by the photoelectric converter to the accumulating part a plurality of times, and makes the accumulating part cumulatively accumulate the electric charge transferred the plurality of times.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010154806-A (JP)
Title: Flavor enhancer and perfume composition
Inventor: NONAKA YUJI
IPC: A23L27/00
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide a flavor enhancer capable of selectively enhancing the flavor of a target perfume, to provide a perfume composition having the enhanced flavor and containing the enhancer, and to provide a beverage.  <P>SOLUTION: The flavor enhancer contains a polymerized catechin as an active ingredient. The flavor enhancer is an additive for beverage, especially tea beverage. The perfume composition contains a perfume and the polymerized catechin. The flavor of a formulated perfume can be enhanced without affecting the flavor of the beverage itself by adding the flavor enhancer to the beverage.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010157153-A (JP)
Title: Order information management device, order information management system configured by using the same and program for managing order information
Inventor: MASUBUCHI HIROSHI
IPC: G06Q30/06
Filed: 2008-12-29
Abstract: <P>PROBLEM TO BE SOLVED: To provide an order information management device for quickly and surely responding to the request of a user, and for preventing the deterioration in a service even though it is possible to reduce personnel expenditure.  <P>SOLUTION: The order information management device includes: an in-facility information storage means for storing unique first identification information applied by a provision facility which provides at least one of merchandise and a service and unique second identification information stored and transmitted by a portable information terminal in association; an order information acquisition means for obtaining the second identification information transmitted from the portable information terminal and the order information of at least one of the merchandise and the service; and an order information transmission means for obtaining the unique first identification information from the user information storage means on the basis of the second identification information in the obtained order information, and for transmitting the first identification information and the order information to the device installed in the provision facility which applies the first identification information.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2008533663-A (JP)
IPC: H01M50/186
Filed: 2005-03-10
Abstract: An electrochemical battery cell with an oxygen reduction electrode and having improved electrolyte leakage resistance. The cell includes a component, disposed between the oxygen reduction electrode and an air inlet in the cell housing, through or around which air can pass. Upon contact with electrolyte, the component is transformed to form an electrolyte seal.
Patent JP-2008534071-A (JP)
Title: ダイナミックな血管の評価を用いた血管状態間の識別のための及び頭蓋内圧の調査ためのシステム及び方法
IPC: A61B8/06
Filed: 2006-03-23
Abstract: 本発明は、単一又は複数の血管及びセグメントの血流を評価し、血管の健康を評価し、臨床実験を行い、効果を得るために治療的介入をスクリーニングし、危険因子を評価し、頭蓋内圧を評価し、そして定義された方法による結果を分析するためのシステム及び方法に関する。本発明は、血管、特に、大脳血管への治療、物質及びデバイスを直接モニタリングできる。関連性のある血流パラメータは、平均流速度、収縮期加速度、及び拍動性インデックスを含む。これらのパラメータ及びその他の測定及び分析は、個々の及び複数の血管の健康に関する詳細を提供し、広範囲の分析は個人の全体的な血管の健康を提供する。本発明は、頭蓋内圧の上昇を経験する個人の発病、進行及び処置の効果を追跡でき、すなわち、水痘症又は認知症と関係があり症状を呈する脈管系下の脆弱性を特定して、正常圧力にするのを助ける。
Patent JP-2008537939-A (JP)
Title: 多相アルキル芳香族の製造
IPC: C07C15/085
Filed: 2006-03-01
Abstract: アルキル化触媒を含む反応領域で、アルキル化可能な芳香族化合物とアルケン化合物を含む別の原材料の混相の混合物を反応させることにより、リアクタ中でモノアルキル化生成物を製造するプロセス。モノアルキル化芳香族生成物とポリアルキル化芳香族化合物を含む流出物は、反応領域から液相で流出する。ポリアルキル化芳香族化合物は、トランスアルキル化反応領域でのトランスアルキル化反応の原材料の流れとして分離することができる。
Patent JP-2008538445-A (JP)
Title: 可撓性成形型を再使用する方法及び微細構造前駆体組成物
IPC: C08F290/00
Filed: 2006-04-13
Abstract: 本発明は、可撓性成形型を用いた微細構造の製造方法、微細構造前駆体組成物及び物品に関する。
Patent JP-2008538587-A (JP)
IPC: A61K39/00
Filed: 2006-04-21
Abstract: Disclosed herein are materials and methods for modulating an immunologically adverse response to an exogenous or endogenous immunogen, including a cell, tissue, or organ associated immunogen. An implantable material comprising cells, such as but not limited to endothelial cells, anchored or embedded in a biocompatible matrix can modulate an adverse immune or inflammatory reaction to exogenous or endogenous immunogens, including response to non-syngeneic or syngeneic cells, tissues or organs, exogenous immunogens or stimuli, as well as ameliorate an autoimmune condition. The implantable material can be provided prior to, coincident with, or subsequent to occurrence of the immune response or inflammatory reaction. The implantable material can induce immunological acceptance in a transplant patient, reduce graft rejection and reduce donor antigen immunogenicity.
Patent JP-2008538700-A (JP)
Title: 免疫エフェクター活性を有するエンドシアリン細胞に内部移行する抗体
IPC: C07K16/28
Filed: 2006-04-24
Abstract: 【解決手段】  本発明は、エンドシアリンを発現する細胞に特異的に結合し、選択的にこの細胞に内部移行し、抗体依存性細胞傷害作用などの免疫エフェクター活性を誘発する能力を有するモノクローナルおよびポリクローナル抗体の利用に関する。前記抗体は、薬物をエンドシアリン発現細胞に特異的に送達し、特に腫瘍細胞および新生血管細胞および前駆体で免疫エフェクター活性を誘発する際に有用である。本発明はまた、本発明の抗体をコード化したヌクレオチドにも関連し、さらに前記抗体を発現する細胞、癌および新生血管細胞を検出する方法、および前記抗体、その誘導体、およびそのフラグメントを用いて癌および血管新生疾患を治療する方法にも関連する。 【選択図】      図３
Patent JP-2008539861-A (JP)
Title: 治療用の微振動装置
IPC: A61H23/02
Filed: 2005-11-10
Abstract: 可聴音響音が付加された状態において、人間の身体を貫通するような動的な誘導磁力場及び電磁的且つ光学的なフォトニック光線場の両方を生成する治療用の微振動マッサージ装置が、細胞エネルギーの増大を誘発し、これによって、痛みを軽減又は除去する治療的な治癒効果を促進している。
Patent JP-2008545523-A (JP)
Title: 保護表面改質系および基材への適用
IPC: B32B27/00
Filed: 2006-05-12
Abstract: 保護表面改質系は、２つの別個の処方を用いて外観を良くし、多くの場合、カウンタートップ等の表面に耐摩耗性を付与する。
Patent JP-2008545730-A (JP)
Title: ピペリジン−４−イルアミド誘導体、およびｓｓｔ受容体サブタイプ５アンタゴニストとしてのその使用
IPC: C07D401/14
Filed: 2006-05-23
Abstract: 本発明は、式（１）（式中、Ｒ １ 〜Ｒ ５ 、Ｒ ５′ 、及びＡは、明細書及び請求項で定義されたとおりである）で示される化合物及び薬学的に許容され得るその塩に関する。本発明は、さらに、上記化合物を含む医薬組成物、それらの製法、ならびにＳＳＴ受容体サブタイプ５の調整に関係する疾患の治療及び／又は予防のためのそれらの使用に関する。
Patent JP-2008542903-A (JP)
Title: セキュリティ照明システムおよび方法並びにそのための制御ユニット
IPC: A01M29/10
Filed: 2006-06-01
Abstract: 【課題】光により望ましくない人または動物を追い払うこと。 【解決手段】本発明は、適当なスイッチング周波数、例えば５〜７０Ｈｚの間で変化する光を提供することにより、望ましくない人または動物（２０）を追い払い、および／またはこれに影響を与えるようになっている、セキュリティ照明システムおよび方法を提供するものである。このシステムの光源（１４ａ、１４ｂ）の照明は、人に対しては約１５〜２０Ｈｚの間の好ましいスイッチング周波数で、強度、色、パターンなどに関して制御ユニット（１２）により変えることができる。望ましくないものが存在していることが検出されたときに、このシステムを起動する近接検出器（１６ａ、１６ｂ）を設けることができる。かかる変化する照明は、動物（２０）を追い払ったり、人を追い払い、または混乱させるのに有効であると分かっている身体的および精神的な不快感を与える。 【選択図】図１
Patent JP-2008544200-A (JP)
Title: 連続回転磁気冷凍機またはヒートポンプ
IPC: F25B21/00
Filed: 2006-06-15
Abstract: 本発明は連続作動反応で作動可能な、工業熱反応に応用可能であると同時に、高効率かつ低製造コストの回転磁気冷凍機/ヒートポンプに関する。回転磁気冷凍機（１０）には磁石（１１）、磁気熱環（１２）、および流体誘導分割組立品（１３）が含まれる。流体誘導分割組立品（１３）には、作用流体（１９，２０，２１，２２）の供給と退避に利用される、上（１７）、下（１８）定置ダクト内にベアリング（１５および１６）付き骨組で懸架される水平体勢回転ディスク（１４）が含まれる。回転ディスク（１４）は中空セクター（２３および２４）の各平滑面に近接する２つの円状配列を有する。すべての中空セクター（２３および２４）に近接する平滑面にはまた回転ディスク（１４）の周囲面のスロット（２５および２６）も含まれる。作用流体は、中空セクターの下部配列の周囲開口部まで放射方向に流れ出すと同時に中空セクターの上部配列の周囲開口部を通ってディスクに戻り、そこから、最終的に上部平滑面にある各中空セクターの開口部を通ってディスクを軸方向に出るために、下部中空セクター内へと軸方向に下部平滑面にある開口部を通って導入される。 【選択図】図１A、図１B
Patent JP-2008543346-A (JP)
Title: 腫瘍壊死因子受容体のプレリガンドアセンブリドメイン（ｐｌａｄ）を標的にすることによる炎症性関節炎の改善
IPC: C12N15/09
Filed: 2006-06-26
Abstract: 本発明は、TNF受容体様受容体のプレリガンドアセンブリドメイン（PLAD）の単離されたアミノ酸配列を含むポリペプチドを提供する。本発明は、プレリガンドアセンブリドメイン（PLAD）の単離されたアミノ酸配列を含むポリペプチドであって、そのPLADが、TNF-RのPLAD、p60のPLAD、p80のPLAD、Fas（CD95/APO-1）のPLAD、TRAIL受容体のPLAD、LTβRのPLAD、CD40のPLAD、CD30のPLAD、CD27のPLAD、HVEMのPLAD、OX40のPLADおよびDR4のPLADからなる群より選択されるポリペプチドも提供する。TNF-R、p60、p80、Fas、TRAIL受容体、LT/βR、CD40、CD30、CD27、HVEM、OX40、DR4、TROY、EDAR、XEDAR、DCR3、AITR、4-1BB、DR3、RANK、TACI、BCMA、DR6、DPG、DR5、DCR1、およびDCR2は、全てTNF受容体スーパーファミリーまたはTNF様受容体ファミリーのメンバーである。本発明は、TNF受容体スーパーファミリーの他のメンバーについてもPLADを提供する。本発明のポリペプチドは、TNF受容体スーパーファミリーメンバーのオリゴマー化を阻害するために利用することができる。これらのポリペプチドは、TNF受容体スーパーファミリーメンバーへのリガンド結合を阻害するために利用することもできる。本発明は、TNF受容体オリゴマー化の阻害剤を含む組成物も提供する。さらに本発明は、PLADを欠くTNF受容体スーパーファミリーのメンバーも提供する。
Patent JP-2009502525-A (JP)
Title: マイクロ流体システム
IPC: B01J19/00
Filed: 2006-07-24
Abstract: マイクロ流体システムは、流体を案内するためのマイクロチャネル構造と、マイクロチャネル構造から少なくとも１つの隔壁によって隔離され熱伝達流体を案内するための他のチャネル構造とを有する。マイクロ流体システムにおける内部漏れの危険を適切な時機に認識することができるようにするために、マイクロチャネル構造（２）が少なくとも１つの個所において他の隔壁（１１）によって空洞（１２）から隔離され、他の隔壁（１１）が、少なくとも局所的に、マイクロチャネル構造（２）と他のチャネル構造（５）との間の隔壁（８）よりも弱く構成され、空洞（１２）が侵入流体を検出するための検出装置（１４）に接続されている。
Patent JP-2009503255-A (JP)
Title: ラージフラットパネルにスパッタリングする方法及び装置
IPC: C23C14/35
Filed: 2006-07-20
Abstract: 矩形スパッタターゲット（１６）の背面に配置され、ターゲットに近接するプラズマトラックに対応して、間にギャップを形成するように配置された反対の極性の磁石（１６４）を有し、プラズマを強化して、ターゲットからスパッタされた材料を矩形パネル（１４）にコートさせる矩形マグネトロン（１６０）。ギャップは、蛇行又は螺旋形状を有する閉鎖ループで延在している。マグネトロンは、ターゲットより幾分小さなサイズであり、ターゲットの２つの垂直な方向に走査される。走査長は、例えば、２ｍのターゲットについては、約１００ｍｍである。走査は、ターゲット側部及び２つの接続対角に平行な２つのリンクに沿って、二重Ｚパターンに従う。チャンバ壁（２７６）で垂直にスライドするガントリ（３６４）からスライド可能に懸架されており、外部アクチュエータ（４１６）は、２次元パスに沿ってマグネトロンを動かす。
Patent JP-2009502173-A (JP)
Title: インビトロでのタンパク質折りたたみのための方法およびシステム
IPC: C12P21/02
Filed: 2006-07-28
Abstract: 再折りたたみされたタンパク質を回収する方法は、変性タンパク質の濃縮溶液と再折りたたみ希釈剤とを静的混合することによって再折りたたみされたタンパク質を得る工程を包含する。この方法は、大処理容量で微生物によって産生された組換えタンパク質に特に適する。この変性タンパク質溶液は、微生物宿主からタンパク質を単離し、そしてこれらを変性剤に曝露することによって得られ得る。この溶液は、タンパク質の適切な折りたたみに適合する静的混合条件下で適切な再折りたたみ希釈剤と混合されることにより、再折りたたみされたタンパク質が、好ましくは迅速かつ高収率で、得られる。