baber/WOPTO huggingface dataset:
Patent AU-2019276592-A1 (AU)
Title: Chimeric antigen receptor T cell therapy
Inventor: XUE XIAODONG
IPC: C12N5/10
Filed: 2019-06-03
Abstract: The disclosure relates to, in part, methods of CAR-T cancer treatment and methods of predicting clinical outcomes in response to those treatments. The methods comprise the use of baseline Sum of Product Diameters of Index Lesions and baseline number of lines of prior therapy as indicators.
Patent AU-2019313854-A1 (AU)
Title: Polymer gel having sponge-like porous structure
Inventor: SAKAI TAKAMASA
IPC: C08L71/02
Filed: 2019-07-29
Abstract: [Problem] The present invention addresses the problem of providing a gel material comprising a solvophilic polymer having a micrometer-scale porous structure.
[Solution] A polymer gel in which solvophilic polymer units are cross-linked to each other, wherein the polymer gel contains a solvent, and has a three-dimensional net-like structure having two regions, i.e., a first region in which the polymer units are present densely and a second region in which the polymer units are present sparsely, and the sizes of nets formed in the first region fall within the range from 1 to 500 μm.
Patent AU-2019346637-A1 (AU)
Title: Multi-axis roll-forming methods, systems, and products
Inventor: LINDER MAXIMILIAN
IPC: B21D5/08
Filed: 2019-09-27
Abstract: A multi-axis roll-forming method includes simultaneously (a) spinning, about a rotation axis, a spin platter having placed thereon a ring encircling the rotation axis, (b) pressing at least one first roller against outward-facing surface of a first portion of the ring to press the first portion against an outward-facing surface of the spin platter, and (c) forcing a second roller against an outward-facing surface of a second portion of the ring to bend toward the rotation axis the second portion, so as to form a lip extending toward the rotation axis, wherein the step of forcing includes (i) pivoting the second roller against the second portion, and (ii) translating the second roller along the second portion toward the rotation axis.
Patent AU-2019358875-A1 (AU)
Title: Combination therapy for treatment and prevention of autoimmune and inflammatory diseases
Inventor: MACKAY CHARLES REAY
IPC: A61P1/00
Filed: 2019-10-09
Abstract: The invention relates to the combination and delivery of compounds for the treatment and prevention of autoimmune and inflammatory diseases. Further, the invention relates to methods of treating a condition associated with effector and/or memory T cells, or other pathogenic immune cells the method comprising, consisting essentially of or consisting of reducing the activity of, or number of, pathogenic immune cells (preferably T cells) in an individual, and providing in the individual, a therapeutically effective amount of at least one type of short chain fatty acid, ester or salt thereof, thereby treating the condition associated with effector and/or memory T cells or other pathogenic immune cells. The present invention also provides compositions for use in methods of the invention.
Patent AU-2019374799-A1 (AU)
Title: Systems and methods for application pre-launch
Inventor: CHAUHAN ABHISHEK
IPC: H04L29/08
Filed: 2019-11-06
Abstract: Embodiments described include systems and methods for management and pre- establishment of network application and secure communication sessions. Session logs may be analyzed to identify an application or secure communication sessions likely to be accessed, and prior to receiving a request to establish the session, an intermediary (e.g. another device such as an intermediary appliance or other device, or an intermediary agent on a client such as a client application) may pre-establish the session, performing any necessary handshaking or credential or key exchange processes. When the session is subsequently requested (e.g. in response to a user request), the system may immediately begin using the pre-established session. This pre-establishment may be coordinated within the enterprise providing load balancing and scheduling of session establishment to prevent large processing loads at any one point in time.
Patent AU-2019380947-A1 (AU)
Title: Packaging product and methods of making and using for box-lining
Inventor: THOMAS LAWRENCE B
IPC: B65D81/03
Filed: 2019-11-15
Abstract: A dunnage product has a length dimension with a first end and a second end opposite the first end. A plurality of segments are distributed along the length dimension between the first end and the second end, including an uncrumpled segment of uncrumpled sheet stock material. The uncrumpled segment is positioned between at least one randomly-crumpled segment of randomly-crumpled sheet stock material on each side of the uncrumpled segment. The uncrumpled segment facilitates easier insertion of the dunnage product into a container and allows for layering a crossing dunnage product without increasing the thickness of the products in the area of overlap.
Patent AU-2019385649-A1 (AU)
Title: Dithiocarbamate oil dispersions
Inventor: QUAGLIA FILIPPO
IPC: A01N59/16
Filed: 2019-11-19
Abstract: Dithiocarbamate oil dispersion comprising a polyamide obtained by reacting a fatty acid, a polyamine and a di- or tri-carboxylic acid in a specific molar ratio and use thereof in agriculture.
Patent AU-2019386140-A1 (AU)
Title: Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
Inventor: BASAR RAFET
IPC: C12N9/22
Filed: 2019-11-27
Abstract: Provided herein are methods for producing immune cells with disruption of multiple genes. Further provided are methods for inserting a chimeric antigen receptor at a gene locus of an immune cell.
Patent AU-2019450349-A1 (AU)
Title: Cell lines for high level production of protein-based pharmaceuticals
Inventor: FORMAN LAWRENCE
IPC: C12N5/00
Filed: 2019-06-10
Abstract: This disclosure provides improved cell lines for manufacture of protein-based pharmaceutical agents, considerably reducing the cost of commercial production. The cell lines are obtained by selecting cells from a mixed population for one or more characteristics that support protein production on a non-specific basis, such as the level of endoplasmic reticulum, Golgi apparatus, and/or other desired phenotypic features, compared with other cells in the starting mixture. Particularly effective producer cell lines can be obtained by preparing the cells for functional selection by making cell hybrids. A gene encoding a therapeutic protein of interest may be transfected into the cells before or after one or more cycles of fusion and selection. Depending on the protein product being expressed, cell lines may be obtained that produce eight grams or more of protein per liter of culture fluid.
Patent AU-2020200008-A1 (AU)
Title: Polymeric bile acid nanocompositions targeting the pancreas and colon
Inventor: FAHMY TAREK M
IPC: A61K31/00
Filed: 2020-01-02
Abstract: Pharmaceutical composition containing poly(bile) acid (PBA) polymers for oral delivery of agent(s) show enhanced uptake by the pancreas, liver, and colon. These nanoparticles show significant retention in the pancreas and colon and are therefore useful for selective delivery. The examples demonstrate efficacy of oral administration of insulin to treat diabetes, and oral induction of tolerance by administration of insulin or ovalbumin in combination with rapamycin. Diabetic animals treated with the insulin or insulin with rapamycin showed normalization of blood glucose levels.
Patent AU-2020203917-A1 (AU)
Title: Antibodies Neutralizing GM-CSF For Use In The Treatment Of Rheumatoid Arthritis Or As Analgesics
Inventor: WAGNER THOMAS
IPC: A61K39/00
Filed: 2020-06-12
Abstract: The invention relates to neutralizing antibodies of GM-CSF and compositions comprising the same 
for use in the treatment of inflammatory disorders such as rheumatoid arthritis according to specific 
dosing regimen. The invention relates also to neutralizing antibodies of GM-CSF and compositions 
comprising the same for use in the treatment of pain, e.g. pain experienced in inflammatory 
disorders such as rheumatoid arthritis, according to specific dosage regimen.
Patent AU-2020209764-A1 (AU)
Title: Powered hair clippers with blade assemblies including blade suspension assemblies
Inventor: JABER ANAS
IPC: B26B19/38
Filed: 2020-01-15
Abstract: A hair clipper includes a clipper body comprising a motor and a blade assembly connected to the clipper body such that the motor moves a blade of the blade assembly during operation. The blade assembly comprising a blade housing and the blade that extends outwardly from an opening in the housing and a linkage that is connected to the blade and biases the blade toward a fully extended configuration. Wherein, upon application of a force against the blade during use that is above a preselected threshold, the blade assembly includes a retracted configuration wherein the blade retracts into the blade housing using the linkage.
Patent AU-2020217347-A1 (AU)
Title: COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION
Inventor: SWAYZE ERIC E
IPC: A61K48/00
Filed: 2020-08-11
Abstract: COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) 
EXPRESSION 
Provided herein are oligomeric compounds with conjugate groups targeting apoplipoprotein 
(a) [apo(a)]. In certain embodiments, the apo(a) targeting oligomeric compounds are 
conjugated to N-Acetylgalactosamine. Also disclosed herein are conjugated oligomeric 
compounds targeting apo(a) for use in decreasing apo(a) to treat, prevent, or ameliorate 
diseases, disorders or conditions related to apo(a) and/or Lp(a). Certain diseases, disorders or 
conditions related to apo(a) and/or Lp(a) include inflammatory, cardiovascular and/or 
metabolic diseases, disorders or conditions. The conjugated oligomeric compounds disclosed 
herein can be used to treat such diseases, disorders or conditions in an individual in need 
thereof.
Patent AU-2020221291-A1 (AU)
Title: Isotopically-stabilized tetronimide compounds
Inventor: OLSEN MARK JON
IPC: A61K31/18
Filed: 2020-02-14
Abstract: Isotopically-stabilized tetronimide compounds comprising one or more deuterium atoms, derivatives, and intermediates, thereof, including methods for their synthesis, pharmaceutical compositions thereof, and methods of using these compounds to interact with target molecules in cell-free samples, cell- and tissue-based assays, animal models, and in a subject are disclosed. One aspect relates to molecules that modulate the expression or catalytic activity of aspartyl (asparaginyl) β-hydroxylase (ASPH) within or on the surface of a cell. Other aspects of the invention relate to use of the molecules disclosed herein to diagnose, ameliorate, or treat cell proliferation disorders and related diseases. Related aspects include uses of the compounds to modulate the activity of viruses, as anti¬ hyperlipidemia agents, and as agents to ameliorate or treat thrombosis and related cardiovascular and metabolic disorders.
Patent AU-2020245405-A1 (AU)
Title: Compositions and methods for treating cystic fibrosis
Inventor: OREN YIFAT
IPC: A61K31/7088
Filed: 2020-03-29
Abstract: The present invention is directed to a method for treating cystic fibrosis (CF) using a splicing modulator, such as an antisense oligonucleotide, capable of inducing the skipping of exon 23, exon 24, or both, of the cystic fibrosis transmembrane conductance regulator (CFTR) pre-mRNA. Also provided are a composition and a kit comprising the splicing modulator, and a method of producing thereof.
Patent AU-2020281049-A1 (AU)
Title: Electronic apparatus and operation method thereof
Inventor: HONG SUN YOUNG
IPC: G06Q50/28
Filed: 2020-07-20
Abstract: Provided is a method and apparatus for recognizing a disposal type of an item 
based on attribute information of the item, and updating information on stock based on 
processing information for the item, which is involved when the item is processed 
5 according to the disposal type.
Patent AU-2020309555-A1 (AU)
Title: High framerate and high dynamic range electron microscopy
Inventor: BLOOM RUTH
IPC: G02B21/36
Filed: 2020-07-08
Abstract: Methods and systems for acquiring transmission electron microscope video data on a rolling-shutter detector at an enhanced frame rate and without temporal distortions are described. Also described are methods to enhance the dynamic range of image and diffraction data acquired using a transmission electron microscope. The disclosed methods and systems may also be applicable to photon detection and imaging systems.
Patent AU-2020328261-A1 (AU)
Title: Intrathecal administration of levetiracetam
Inventor: MITIDIERI AUGUSTO
IPC: A61K31/195
Filed: 2020-08-12
Abstract: Methods of treatment, pharmaceutically acceptable solutions, and implantable devices are provided for the intrathecal treatment of AED-resistant seizures using levetiracetam.
Patent AU-2020345173-A1 (AU)
Title: Coupling mechanism
Inventor: TOLLEY MARK
IPC: E21B23/02
Filed: 2020-09-10
Abstract: A coupling mechanism is disclosed for coupling a wireless communication device (48) to a locating profile (50) in a wellbore. The coupling mechanism (10) comprises a coupling body (12) arranged for connection to the wireless communication device (48), and an anchoring unit (14). The coupling body includes a conical portion (24) with a tapered outer surface. The anchoring unit (14) has a tapered inner surface arranged to oppose the tapered outer surface of the coupling body. The coupling body (12) and the anchoring unit (14) are configured for relative movement to cause the anchoring unit to expand radially to grip the locating profile (50).
Patent AU-2020360532-A1 (AU)
Title: Oxidation of santalene to santalol
Inventor: CALLANT DOMINIQUE
IPC: C07C22/00
Filed: 2020-09-25
Abstract: The invention relates to a process for the oxidation of santalene to santalol. The starting mate- rial is in particular a mixture comprising alpha-santalene, beta-santalene, epi-beta-santalene, trans-alpha-bergamotene and beta-bisabolene. The oxidation of the santalenes occurs via an intermediate chloro-santalene compound. Substitution of the chloro-substituent by acetate yielded the mixture of the corresponding santalyl actates, which were hydrolyzed to yield the corresponding mixture of santalols.
Patent AU-2020365708-A1 (AU)
Title: Dart game device
Inventor: LEE SEUNG YOON
IPC: F41J3/00
Filed: 2020-08-10
Abstract: Disclosed is a dart game device according to some embodiments of the present disclosure. The dart game device may comprise: a body part which forms the exterior of the dart game device; a target fixing plate provided in one area of the front surface of the body part; a dart target part seated on the front surface of the target fixing plate; and a target cover part configured to cover at least a part of the dart target part and fixed and coupled to the target fixing plate.
Patent AU-2020366736-A1 (AU)
Title: Composition, production method, and usage
Inventor: FUJII KENGO
IPC: A61K35/741
Filed: 2020-03-19
Abstract: Provided are: a composition that includes bacterium powder and fatty oil and has suppressed caking of the bacterium powder; a production method; and a usage.　A composition including bacterium powder, fatty oil, and at least one type selected from the group consisting of a micro-powder and a surfactant; a production method therefor; and a usage as an anti-caking agent for bacterium powder, in at least one type of composition that includes fatty oil and is selected from the group consisting of a micro-powder and a surfactant.
Patent AU-2020403727-A1 (AU)
Title: Loose product dispenser
Inventor: EVANGELISTI PAOLO
IPC: A47J42/50
Filed: 2020-12-09
Abstract: The loose product dispenser (1) comprises a container (2) and a sensor (3) with optical barrier (5) for detecting the presence of loose product in the container (2), the sensor (3) comprising a transmitter (4) of a light beam, configured to generate the optical barrier (5) between an entry point (7) and an exit point (8) of the light beam from the container (2), and a receiver (6) of the light beam, the sensor (3) further comprises an electronic board (9) on which both the receiver (6) and the transmitter (4) are installed, and a light guide (10) configured and arranged to transmit to the receiver (6) the light beam collected from the exit point (8).
Patent AU-2020407437-A1 (AU)
Title: Engineered platelets for targeted delivery of a therapeutic agent
Inventor: PATTERSON JAMES
IPC: A61K35/19
Filed: 2020-12-16
Abstract: The present invention provides engineered platelets with chimeric platelet receptors (CPR) with a desired target specificity. Additionally, the engineered platelets may comprise cargo which may be released upon activation of the platelet. Additionally, the platelets may be generated
Patent AU-2020414363-A1 (AU)
Title: Plasma creation and heating via magnetic reconnection in an encapsulated linear ring cusp
Inventor: MCGUIRE THOMAS JOHN
IPC: G21B1/05
Filed: 2020-12-02
Abstract: In one embodiment, a fusion reactor includes an enclosure, one or more internal magnetic coils suspended within an interior of the enclosure and co-axial with a center axis of the enclosure, one or more encapsulating magnetic coils co-axial with the center axis of the enclosure, the encapsulating magnetic coils having a larger diameter than the internal magnetic coils, one or more mirror magnetic coils co-axial with the center axis of the enclosure, and one or more magnetic reconnection coils co-axial with the center axis of the enclosure, wherein the one or more magnetic reconnection coils, when pulsed by a power source, are disposed to reconfigure one or more magnetic fields within the enclosure. The reconfiguration, or magnetic reconnection, of the one or more magnetic fields is disposed to increase energy in the magnetic fields, thereby facilitating the conditions operable to generate plasma, and further, when the magnetic fields are collapsed, releasing the energy into the plasma.
Patent AU-2020436036-A1 (AU)
Title: Robot cleaner
Inventor: Hong woo
IPC: A47L11/40
Filed: 2020-12-07
Abstract: The present invention relates to a robot cleaner comprising a shielding module provided under a cleaner body, wherein the shielding module includes a cam and a hiding plate which rotate with the same phase angle about a same rotating shaft. The distance between the center of the hiding plate and the center of the rotating shaft is configured to be longer than the distance between a contact point on an inclined surface of the cam and the center of the rotating shaft, wherein a guide protrusion of a bumper is in contact with the inclined surface at the contact point. Therefore, the rotation movement speed of the hiding plate which rotates to hide a cliff sensor is much faster than the inner movement speed of the bumper. Accordingly, the present invention can improve sensitivity to the detection of a collision between the bumper and an obstacle by using the cliff sensor.
Patent AU-2020436274-A1 (AU)
Title: Wear resistant composite
Inventor: LARSSON OSKAR
IPC: C22C49/14
Filed: 2020-12-08
Abstract: A composite body and a method for producing an integrally cast composite body, which includes at least two zones. A first zone is substantially formed of metal material, and, a second zone additionally includes a non-metallic reinforcing material, such as cement carbide. The composite body is particularly useful for producing products which have at least one wear resistant zone or surface.
Patent AU-2020440785-A1 (AU)
Title: Fresh air module and air conditioner
Inventor: ZHOU YUANLE
IPC: F24F1/0073
Filed: 2020-11-17
Abstract: A fresh air module, comprises a housing (10), a fan assembly, and a motor cover (30), the housing (10) being provided with a fresh air inlet (102) and a fresh air outlet (103), and a fresh air duct (101) being formed in the housing (10). The fan assembly comprises a motor and a wind wheel (60), the wind wheel (60) being disposed in the fresh air duct (101). The motor cover (30) is mounted to the housing (10) and is located outside the fresh air duct (101), a motor accommodating cavity is formed in the motor cover (30), and a motor body (32) is disposed in the motor accommodating cavity. A partition (40) is provided between the motor accommodating cavity and the fresh air duct (101) to partition the motor accommodating cavity and the fresh air duct (101), and a motor shaft (31) passes through the partition (40) and is drivingly connected to the wind wheel (60).
Patent AU-2020449203-A1 (AU)
Title: Cutting position control device
Inventor: HOUSHUYAMA KAZUHIRO
IPC: B21B1/46
Filed: 2020-05-22
Abstract: A cutting position control device according to an embodiment of the present invention is provided with an arithmetic processing circuit for: receiving an input of first data related to a production schedule and material information for a material being produced; calculating, on the basis of the first data, a first cutting position by a first cutting machine on a first slab that is cast by continuous casting equipment; generating a first parameter for setting the first cutting position for a control program introduced into a process control device; comparing a first length that has been set from the distal end of the first slab to the first cutting position, and a second length of a second slab that has been cut from the first slab on the basis of the first parameter; and determining whether to cut the second slab also by means of a second cutting machine provided downstream from the first cutting machine.
Patent WO-2021237303-A1 (WO)
Title: Drive side liner for a centrifugal pump
Inventor: KOSMICKI RANDY JAMES
IPC: F16B2/12
Filed: 2021-05-28
Abstract: There is provided a drive side liner for a centrifugal slurry pump, wherein the centrifugal slurry pump includes an outer casing, a main liner and an impeller driven by a drive shaft, wherein the main liner and drive side liner are housed within the outer casing of the centrifugal slurry pump, the drive side liner including: an inner liner portion including a central aperture configured to receive the drive shaft, the drive side liner further including an outer liner portion arranged to surround the inner liner portion, wherein the inner liner portion and the outer liner portion are each configured to removably engage with one another and the outer casing.
Patent WO-2021253083-A1 (WO)
Title: Method of extraction
Inventor: MOUNTFORT RAMON DUDLEY
IPC: C09F1/02
Filed: 2021-06-16
Abstract: The present disclosure relates to methods and an apparatus for extracting terpenes and rosin from resinous wood with an agent that comprises, consists or consists essentially of a terpene to thereby extract the rosin and/or terpene fractions from the resinous wood. The apparatus for extracting rosin and/or terpene fractions comprises a treatment chamber for treating the resinous wood with the agent. The treatment chamber is in communication with a distillation chamber for separating the rosin and terpene fractions extracted from the resinous wood.
Patent WO-2022073068-A1 (WO)
Title: Generating brain network impact scores
Inventor: SUGHRUE MICHAEL EDWARD
IPC: G16H30/40
Filed: 2021-10-07
Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating a mental health prediction for a patient. One of the methods includes obtaining brain data captured by one or more sensors characterizing a brain of a patient; determining a network graph from the brain data, wherein: a node of the network graph corresponds to a parcellation in the brain of the patient, and a subset of nodes of the network graph corresponds to a particular functional area of the brain; generating, for each of a plurality of nodes in the network graph, a measure of centrality of the node; generating, for the particular functional area of the brain and using the generated measures of centrality, a health score representing a measure of health of the functional area of the brain; generating a mental health prediction for the patient using the health score.