baber/WOPTO huggingface dataset:
Patent WO-2019169096-A1 (WO)
Inventor: HARRIS II JOHN ROBERT
IPC: B26B21/52
Filed: 2019-02-28
Abstract: A two way razor is disclosed having a handle, a bracket, and a shaving head mounting dual opposing shaving cartridges each comprising a plurality of razor blades, and a swivel mechanism disposed between the handle and the bracket for exchanging the positions of the first and second cartridges' positions, the swivel mechanism comprising first and second disks where a first disk has two projections at opposite ends and a second disk has two recesses at opposite ends, such that the projections and recesses engage to lock the bracket in first and second orientations with respect to the handle.
Patent WO-2019173173-A1 (WO)
Title: Process and intermidiates for the preparation of certain mesoionic pesticides
Inventor: DUMAS DONALD J
IPC: A01N43/90
Filed: 2019-03-04
Abstract: The present invention provides a method for preparing a compound of Formula (B), Formula (C), or Formula (D): wherein Q is a 3- to 10- membered ring system containing ring members selected from carbon atoms and up to 4 heteroatoms independently selected from up to 2 O, up to 2 S, and up to 4 N, wherein up to 3 carbon atom ring members are independently selected from C(=O) and C(=S) and such ring system is optionally substituted with up to 5 substituents independently selected from R A ; each R A  is independently halogen, hydroxy, SF 5 , C(O)(C 1 -C 8  alkyl), C(O)O(C 1 -C 8  alkyl), N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), C(O)N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), C(=S)N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), SO 2 N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), OC(O)(C 1 -C 8  alkyl), OC(O)O(C 1 -C 8  alkyl), OC(O)N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), N(C 1 -C 8  alkyl)C(O)O(C 1 -C 8  alkyl), N(C 1 -C 8  alkyl)C(O)N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), OSO 2 (C 1 -C 8  alkyl), OSO 2 N(C 1 -C 8  alkyl)(C 1 -C 8  alkyl), N(C 1 -C 8  alkyl)SO 2 (C 1 -C 8  alkyl), or CC 1 -C 8  alkyl, C 1 -C 8  haloalkyl, C 2 -C 8  alkenyl, C 2 -C 8  alkynyl, C 3 -C 10  cycloalkyl, C 3 -C 10  halocycloalkyl, C 4 -C 10  alkylcycloalkyl, C 4 -C 10  cycloalkylalkyl, C 6 -C 14  cycloalkylcycloalkyl, C 5 -C 10  alkylcycloalkylalkyl, C 3 -C 8  cycloalkenyl, C 1 -C 8  alkoxy, C 1 -C 8  haloalkoxy, C 3 -C 8  cycloalkoxy, C 3 -C 8  halocycloalkoxy, C 4 -C 10  cycloalkylalkoxy, C 2 -C 8  alkenyloxy, C 2 -C 8  alkynyloxy, C 1 -C 8  alkylthio, C 1 -C 8  alkylsulfinyl, C 1 -C 8  alkylsulfonyl, C 3 -C 8  cycloalkylthio, C 3 -C 8  cycloalkylsulfinyl, C 3 -C 8  cycloalkylsulfonyl, C 4 -C 10  cycloalkylalkylthio, C 4 -C 10  cycloalkylalkylsulfinyl, C 4 -C 10  cycloalkylalkylsulfonyl, C 2 -C 8  alkenylthio, C 2 -C 8  alkenylsulfinyl, C 2 -C 8  alkenylsulfonyl, C 2 -C 8  alkynylthio, C 2 -C 8  alkynylsulfinyl or C 2 -C 8  alkynylsulfonyl; or two R A  substituents on adjacent ring atoms are taken together to form a 5- to 7- membered carbocyclic or heterocyclic ring, each ring containing ring members selected from carbon atoms and up to 3 heteroatoms independently selected from up to 2 O, up to 2 S, and up to 3 N, wherein up to 2 carbon atom ring members are independently selected from C(O) and C(=S) and such ring is optionally substituted with up to 3 substituents independently selected from the group consisting of halogen, hydroxy, C 1 -C 4  alkyl, C 1 -C 4  haloalkyl, C 2 -C 4  alkenyl, C 2 -C 4  haloalkenyl, C 2 -C 4  alkynyl, C 2 -C 4  haloalkynyl, C 3 -C 7  cycloalkyl, C 3 -C 7  halocycloalkyl, C 4 -C 8  alkylcycloalkyl, C 4 -C 8  haloalkylcycloalkyl, C 4 -C 8  cycloalkylalkyl, C 4 -C 8  halocycloalkylalkyl, C 1 -C 8  alkoxy, C 1 -C 8  haloalkoxy, C 2 -C 8  alkoxycarbonyl, C 2 -C 6  haloalkoxycarbonyl, C 2 -C 6  alkylcarbonyl and C 2 -C 6  haloalkylcarbonyl; each of R 2  and R 3  is independently H, F, C 1 -C 4  alkyl or C 1 -C 4  haloalkyl; and M is an inorganic cation or organic cation.
Patent WO-2019178405-A1 (WO)
Title: Modular welding mold
Inventor: ROIS STEVEN
IPC: H01R4/02
Filed: 2019-03-14
Abstract: A welding system for use with exothermic welding material to weld conductors together can include a reusable mold body and a set of solid inserts configured to receive conductors and to define a weld chamber. Molten weld material can be delivered to the weld chamber from the reusable mold body to create a welded connection between the conductors.
Patent WO-2019178443-A1 (WO)
Title: Yeast cell wall particle encapsulation of biodegradable pro-payloads
Inventor: OSTROFF GARY R
IPC: A61K9/14
Filed: 2019-03-15
Abstract: The present disclosure provides a particulate delivery system comprising extracted yeast cell wall comprising beta-glucan and a pro-payload molecule comprising a payload scaffolding molecule operably and reversibly linked to a payload molecule through a cleavable linker. The disclosure further provides methods of making and methods of using the particulate delivery system.
Patent WO-2019209632-A1 (WO)
Title: Scalable chromatography process for purification of human cytomegalovirus
Inventor: KRISTOPEIT ADAM
IPC: A61K47/02
Filed: 2019-04-19
Abstract: The present invention relates to a scalable process for the purification of human cytomegalovirus particles from cell culture medium. In particular, the process involves a two step chromatography process starting with an anion exchange chromatography step followed by a polishing chromatography step selected from mixed mode chromatography or cation exchange chromatography.
Patent WO-2019209815-A1 (WO)
Title: Compact antenna phase shifter with simplified drive mechanism
Inventor: LITTEER ANDREW
IPC: H01Q3/36
Filed: 2019-04-23
Abstract: Disclosed is a phase shifter arrangement for an antenna, such as a cellular antenna, that has a simplified drive mechanism. The phase shifter arrangement has two phase shifters, each with two wiper arms that are coupled at one end to a single drive shaft. Each of the wiper arms have a pivot access that may be located at or near its center such that as the drive shaft translates, it mechanically engages both wiper arms, causing them to rotate around their respective pivot axes. Certain antenna arrangements have several array faces. For example, the antenna may have three array faces, each spaced at 120 degrees of azimuth. The drive shafts for each of these array faces may operate independently to function as a multisector antenna, or they may be driven in unison to function as an omnidirectional antenna.
Patent WO-2019210201-A1 (WO)
Title: System and method for proximity detection with single-antenna device
Inventor: PIERSON TIMOTHY J
IPC: H04W4/02
Filed: 2019-04-26
Abstract: A single-antenna device includes a single antenna, at least one processor, and at least one memory. The single-antenna device is operable to receive a signal including at least one frame. Each of said frame includes a repeating portion. The single-antenna device determines a difference of phase and amplitude of the repeating portion and further determines whether the signal is transmitted from a trusted source based at least in part on the difference of phase and amplitude of the repeating portion.
Patent WO-2019213023-A1 (WO)
Title: System and method for environmental monitoring
Inventor: GUEST ANNA
IPC: B23K26/08
Filed: 2019-04-30
Abstract: A system and method for monitoring an environment and performing analysis of collected samples are provided. The samples can be collected by personnel, a robot or a cobot, and the system may receive results of the monitoring/analysis and output information (e.g., alerts, reports, trends, forecasts) to environmental services, infection prevention personnel, and/or an electronic health/medical record system. If a contaminant is detected in the environment, appropriate personnel may automatically be alerted so that the contaminant can be eliminated/contained. The system may dynamically schedule the monitoring based on needs and ongoing changes in the environment, provide routing and work instructions to personnel, robots and/or cobots, and manage, maintain, and organize all information associated with the environmental monitoring so that information can be accessed, analyzed, and, if necessary, responded to, in real-time and/or in a timely manner, or where corrective actions need to be initiated as part of overall improvement plans.
Patent WO-2019226838-A1 (WO)
Title: Methods and apparatus for intra-cell and inter-frequency optimization in a quasi-licensed wireless system
Inventor: HMIMY HOSSAM
IPC: H04W36/18
Filed: 2019-05-22
Abstract: Methods and apparatus for providing quasi-licensed intra-cell spectrum reassignment. In one embodiment, the quasi-licensed spectrum utilizes 3.5 GHz CBRS (Citizens Broadband Radio Service) spectrum, and a "seamless" reassignment of wireless spectrum without disruption or loss of continuity to existing data sessions of the CBSD is provided via a pool of temporary RF carriers which act as substitutes for the currently allocated (granted) carriers. The served user devices (e.g., UEs) are instructed by the CBSD to migrate to a new "final" carrier via the substitutes, either directly or via one or more intermediary hops. In one variant, existing 3GPP signaling mechanisms between the UE and CBSD/eNodeB obviates any changes to extant UEs. Communications between the CBSD and its cognizant S AS/DP include new information objects which direct the CBSD to implement the handover functionality. In a further variant, inter-CBSD sector and frequency handovers are provided for using CBRS-plane and 3GPP signaling.
Patent WO-2019232538-A1 (WO)
Title: Process for molding cover materials for seating applications
Inventor: KOZLOWSKI ERIC
IPC: B32B9/02
Filed: 2019-06-03
Abstract: A seat trim cover for an automotive seat is formed into a 3-dimensional shape by compression molding a laminated moldable foam in a 3-dimensional. The laminated moldable foam comprises at least a layer of cellular polyurethane foam compression moldable in a temperature range of about 220°F to about 260°F. The 3-dimensional mold is heated to a temperature range of about 150°F to about 320°F. The layer of cellular foam is adhered to a cover material layer and precut into a pre-laminated blank prior to molding into the 3-dimensional shape. Optionally, seat heaters or other components can be integrated with the laminated foam prior to compression molding the seat trim cover.
Patent WO-2020180341-A1 (WO)
Title: Methods for fabricating printed circuit board assemblies with high density via array
Inventor: LEN MICHAEL
IPC: H05K1/02
Filed: 2019-06-07
Abstract: A method is provided for forming a printed circuit board (PCB) assembly. The method may include drilling a first plurality of vias having a first diameter in a PCB and filling the first plurality of vias to form a first plurality of plated or filled vias. The method may also include drilling a second plurality of vias having a second diameter in the PCB, and filling the second plurality of vias to form a second plurality of plated or filled vias. The first plurality of plated or filled vias is mixed with the second plurality of plated or filled vias such that the spacing between the first plurality of plated or filled vias and the second plurality of plated or filled vias is less than the first diameter and the second diameter.
Patent WO-2020006073-A1 (WO)
Title: Dispensing method for producing dissolvable unit dose film constructs
Inventor: BARNHART SCOTT D
IPC: A61K47/10
Filed: 2019-06-26
Abstract: Dissolvable unit dose film constructs are made by providing a muco-adhesive composition including a muco-adhesive polymer matrix in which the muco-adhesive polymer matrix has a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof and a liquid carrier. The method further includes drying the muco-adhesive composition to remove at least a portion of the liquid carrier, forming a muco-adhesive film substrate, forming a composition for an active layer, the composition including a polymer matrix in which the polymer matrix for the active layer composition includes a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof, an active ingredient and a liquid carrier. The method further includes depositing the composition for the active layer onto the muco-adhesive substrate as a plurality of individual volumes and removing the liquid carrier from the plurality of deposited individual volumes to form a plurality of dissolvable film active layers on the muco-adhesive substrate.
Patent WO-2020006368-A1 (WO)
Title: Active waveguide for high-power laser
Inventor: SCHERBAKOV EUGENE
IPC: H01S3/067
Filed: 2019-06-28
Abstract: An active waveguide including active and passive rods which have respective polymeric claddings mechanically and optically coupled to one another so as to define a side pumping scheme. One or a plurality of elements are embedded in one of or both active and passive rods and have a refractive index lower than the lowest of refractive indices of the respective active and passive rods at at least 1*10 -3 . The MM core of the active rod includes inner and outer concentric regions with a concentration of light emitters in the outer region being lower than that of the inner region at more than 50 % and, a radius of the inner region being at most 92 % of that of the outer region. The unabsorbed pump light at the output of the active waveguide constitutes less than 1 % of the delivered pump light which in combination with the refractive index of the embedded elements and selectively doped core regions contribute to laser efficiency of at least 86 %.
Patent WO-2020014120-A1 (WO)
Title: Measured dose dispenser and methods of using the same
Inventor: SCOTTON JAMES E
IPC: B65D83/04
Filed: 2019-07-08
Abstract: A two-piece measured-dose dispensing closure (10) includes a cup-shaped measuring chamber (12) and a rotatable dispensing control lid (14). In use, the dispensing control lid is axially moved relative to the measuring chamber by rotation between a first closed position, a second intermediate dispensing position, and a third drain position.
Patent WO-2020023620-A1 (WO)
Title: Methods and compositions of chemically modified phage libraries
Inventor: GAO JIANMIN
IPC: C07K1/13
Filed: 2019-07-24
Abstract: Provided is a chemically modified phage display platform and method of use thereof. More specifically, the present disclosure provides a chemically modified phage display library that incorporates 2-acetylphenylboronic acid (APBA) moieties to elicit dynamic covalent binding to the bacterial cell surface. The APBA-modified phage display libraries described herein are applicable to a wide array of bacterial strains and/or mammalian cells, paving the way to facile diagnosis and development of strain-specific antibiotics, and/or peptide-antibiotic conjugates for effective and targeted treatment. Also provided are therapeutic peptides, and pharmaceutical compositions thereof, that are identified by screening the phage display library of the present disclosure, and method of use of such therapeutic peptides for effective and targeted treatment.
Patent WO-2020028663-A1 (WO)
Title: Cutting tool with pcd inserts, systems incorporating same and related methods
Inventor: BURTON REGAN LELAND
IPC: E21B10/43
Filed: 2019-08-01
Abstract: A cutting tool which may be used in machining various material may include a body and one or more cutting elements associated therewith. In one example, the cutting element(s) may comprise a superhard table, such as a polycrystalline diamond table. In some embodiments, the polycrystalline diamond table may have a diamond density of approximately 95 percent volume or greater. In some embodiments, the thickness of the superhard table may be approximately 0.15 inch. In some embodiments, the superhard table may include a chip breaking feature or structure. Methods of shaping, finishing or otherwise machining materials are also provided, including the machining of materials comprising titanium.
Patent WO-2020033279-A1 (WO)
Title: Compactable rf membrane antenna and methods of making
Inventor: PALISOC LIBORNIO
IPC: B29C70/40
Filed: 2019-08-04
Abstract: Exemplary embodiments are described herein for compactable antennas and methods of making such an antenna. Exemplary compactable antennas include a support structure and a reflector surface. The support structure may directly or indirectly define the reflector shape. Exemplary embodiments comprise deployable support structures to permit the compactable antenna to have a smaller volume stowed configuration and a larger volume deployed configuration.
Patent WO-2020033814-A1 (WO)
Title: Compositions and methods related to overcoming innate immune barriers to cancer immunotherapy
Inventor: SEGAL BRAHM
IPC: G01N33/569
Filed: 2019-08-09
Abstract: Provided are methods for identifing and treating individuals who have cancer, and also have immunosuppressive neutrophils. The method of treating includes administering one or more drugs that inhibit formation of immunosuppressive neutrophils. Cancer patients can be identified, and selected for treatment, based on a positive result obtained by exposing a biological sample from the patient to normal neutrophils, and subsequently exposing the neutrophils to T cells, and measuring activation of T the cells. Reduced activation of the T cells relative to a control provides an indication that the individual has the immunosuppressive neutrophils, and is a candidate to receive the drug. The drug administered to the cancer patient functions to inhibit SNARE-dependent exocytosis, or inhibits NADPH oxidase, or inhibits complement signaling. The method further includes administering to the individual an immune checkpoint inhibitor, which may increase the efficacy of the checkpoint inhibitor.
Patent WO-2020061125-A1 (WO)
Inventor: KIRKWOOD JASON
IPC: H01L21/66
Filed: 2019-09-18
Abstract: A system for defect detection and analysis is provided. The system may include an inspection sub-system and a controller including a memory and one or more processors. The inspection sub-system may include an illumination source and one or more detectors configured to acquire control patch images of defects of a control specimen along one or more detector channels. The one or more processors may be configured to train a defect classifier using the control patch images and known parameters associated with the defects of the control specimen. The inspection sub-system may be further configured to acquire patch images of identified defects on an additional specimen. The one or more processors may be configured to determine parameters of the identified defects using the defect classifier.
Patent WO-2020081599-A1 (WO)
Title: Separation of vancomycin and its degradation products
Inventor: RILEY CHRISTOPHER
IPC: C07K1/16
Filed: 2019-10-15
Abstract: Disclosed is a chromatographic method for separating a mixture of compounds having ionizable groups using a mobile phase comprising (a) a first mobile phase component comprising an aqueous buffer system and an organic solvent mixture miscible with water, and (b) a second mobile phase component comprising an aqueous buffer system and an organic solvent mixture miscible with water, wherein the buffer system and the solvent mixture in the first mobile phase component are different from the buffer system and the solvent mixture in the second mobile phase component and the ratio of the first mobile phase component to the second mobile phase component is varied during the separation. The method can be used for the separation of vancomycin and its degradation products.
Patent WO-2020081601-A1 (WO)
Title: Methods of treating pancreatic cancer using coenzyme q10
Inventor: SARANGARAJAN RANGAPRASAD
IPC: C07C50/06
Filed: 2019-10-15
Abstract: The disclosure provides methods of treating pancreatic cancer in a population of subjects comprising administration of Coenzyme Q10. Administration of Coenzyme Q10 to the subjects increases the number of subjects in the population that exhibit stable disease. In addition, administration of Coenzyme Q10 to the subjects increases progression free survival, overall survival, and time to progression in the population of pancreatic cancer patients.
Patent WO-2020086384-A1 (WO)
Title: Universal pointers for data exchange in a computer system having independent processors
Inventor: WALLACH STEVEN JEFFREY
IPC: G06F9/46
Filed: 2019-10-17
Abstract: A system, method and apparatus to facilitate data exchange via pointers. For example, in a computing system having a first processor and a second processor that is separate and independent from the first processor, the first processor can run a program configured to use a pointer identifying a virtual memory address having an ID of an object and an offset within the object. The first processor can use the virtual memory address to store data at a memory location in the computing system and/or identify a routine at the memory location for execution by the second processor. After the pointer is communicated from the first processor to the second processor, the second processor can access the same memory location identified by the virtual memory address. The second processor may operate on the data stored at the memory location or load the routine from the memory location for execution.
Patent WO-2020097278-A1 (WO)
Title: Multi-channel remote temperature monitor
Inventor: AUSTIN JOHN
IPC: G06F12/06
Filed: 2019-11-07
Abstract: A system includes a conditioning circuit, resistors connected to pins of the conditioning circuit, and measurement sensors connected to pins of the conditioning circuit. The conditioning circuit is configured to determine resistance values of the resistors and to determine a set of addresses for the measurement sensors based upon a combination of the resistance values of the resistors.
Patent WO-2020106653-A1 (WO)
Inventor: POIRIER TANGI
IPC: H04N19/593
Filed: 2019-11-19
Abstract: A chroma component block vector is initialized using one of a neighboring or collocated luma block vector when current picture referencing mode is used and when dual tree is enabled. In a first embodiment, if a collocated luminance block is not coded in current picture reference mode, a luma vector from a left chroma subblock is used. When the left chroma subblock is not coded in current picture reference mode, a luma vector from the above chroma subblock is used, and if that is not available, a default vector is used. In a second embodiment, a collocated luma block partition is used to derive a chroma block vector.
Patent WO-2021107940-A1 (WO)
Inventor: DUGGAL ROHIT
IPC: C07K14/735
Filed: 2019-11-26
Abstract: Disclosed herein are recombinant nucleic acids, comprising a 5' untranslated (5'-UTR) sequence portion, a signal peptide sequence portion, a single chain antibody fragment sequence portion, a hinge region sequence portion, a transmembrane domain sequence portion, and one or more intracellular domain sequence portions. Also disclosed herein are modified natural killer (NK) cells comprising the recombinant nucleic acid described above. Further disclosed herein are methods of treating a tumor in a subject by administering the modified NK cells.
Patent WO-2020123693-A1 (WO)
Title: Jeton de commande et commande dynamique hiérarchique
Inventor: DURVASULA SREENIVAS
IPC: G06F9/48
Filed: 2019-12-11
Abstract: La présente invention concerne des systèmes et des procédés qui permettent de faciliter une interruption ou un changement dans des tâches automatisées en cours, et d'utiliser un jeton de commande (par exemple un drapeau) pour modifier la progression de la tâche automatisée. Contrairement aux tâches automatisées actuelles qui ne peuvent pas être modifiées une fois que la requête de tâche automatisée a été envoyée, les techniques décrites par les présentes permettent de commander et/ou de modifier une tâche automatisée, par utilisation du jeton de commande, et un état associé conjointement avec des points de contrôle logiques (136, 142) défini pour un fil (122, 124) au niveau duquel le fil (122, 124) peut être mis en pause et l'état changé.