baber/WOPTO huggingface dataset:
Patent AT-E468068-T1 (AT)
Inventor: PARKER DAWOOD
IPC: A61B5/00
Filed: 1999-07-02
Granted: 2010-06-15
Abstract: An apparatus for the measurement of at least one analyte in the blood of a patient, which includes a light source generating broadband light and a light-transmission arrangement having a plurality of transmitting fibers is positioned for simultaneously transmitting multiple wavelengths of the broadband light from the light source to the blood of the patient. The measurement apparatus further includes an optical fiber arrangement having a plurality of light detector fibers for leading multi-wavelength light, in spectrally unseparated form, transmitted through, or reflected from, the blood and a light detection arrangement for receiving the multi-wavelength light in its spectrally unseparated form from the optical fiber arrangement, for spectrally decomposing the received light, and for determining amplitudes of selected wavelengths of the decomposed light. The measurement apparatus utilizes a non-pulsatile element of the patient's blood for determining the measurement of at least one analyte in the blood as a function of the amplitudes of the selected wavelengths.
Patent AT-E220215-T1 (AT)
Inventor: AMOS WILLIAM BRADSHAW
IPC: G02B21/18
Filed: 1999-07-15
Granted: 2002-07-15
Abstract: A confocal scanning optical microscope system wherein a dispersive optical device such as a prism separates an image from a restricted area of a specimen into a spread of images of differing wavelengths. Different parts of the spread of images are focused at respective beam-limiting apertures which are conjugate with one another, and the spectrally differing beams passing through the beam-limiting apertures pass to respective detectors.
Patent AT-E283820-T1 (AT)
Inventor: HAHN NORBERT
IPC: B65G69/28
Filed: 1999-07-09
Granted: 2004-12-15
Abstract: A dock leveler mountable in a pit including a rear wall, the leveler including a deck with a front end and that is capable of pivotal movement relative to the rear wall; a lip capable of movement to a substantially coplanar position relative to the deck; and a bumper mounted adjacent the deck front end beyond the lateral width of the lip.
Patent AT-E512231-T1 (AT)
Inventor: WEINER DAVID
IPC: C12N15/09
Filed: 1999-02-26
Granted: 2011-06-15
Abstract: Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines, recombinant vaccines for delivering foreign antigen and live attenuated vaccines. Methods of immunizing individuals are disclosed. Compositions for and methods of treating individuals with autoimmune diseases are disclosed.
Patent AT-E223174-T1 (AT)
Inventor: PLANCA RINALDO
IPC: A47J42/56
Filed: 1999-10-02
Granted: 2002-09-15
Abstract: The invention is related to an electrical appliance from the type blender of food processor, comprising a base including an electric motor, a container able to be removably secured on said base, said container having a cylindrical open top, a food processing tool mounted in the bottom of said container and able to be driven by said motor, a lid able to close said container, means for limiting axial movement of the lid, means for limiting rotational movement of the lid, a safety device including a pin mounted on the container and a switch mounted on the base, the lid including means for actuating the pin to operate the switch in order to enable motor operation when the lid occupies a closed operating position on the container, wherein a locking button is provided on the container, said button being able to actuate a lock able to bear against an abutment or to enter a notch, said notch or said abutment being provide on the lid, to lock the lid on the container in the closed operating position.
Patent AT-E279419-T1 (AT)
Inventor: GERKE THOMAS
IPC: A61K8/58
Filed: 1999-08-31
Granted: 2004-10-15
Abstract: The invention relates to silicic-acid esters of formula (I) in which R<1> and R<4> are selected, independent of one another, from the group of straight-chain or branched, saturated or unsaturated, substituted or non-substituted C1-C6 hydrocarbon radicals and of the aromatic alcohol radicals. Each R<2> and R<3> is selected, independent of one another, from the group of aromatic alcohol radicals, and n takes on values between 2 and 20. These esters of oligo silicic acids comprising aromatic alcohols are characterized by having a good hydrolytic stability and can also be used in aqueous media or in processes for producing granulates without resulting in excessive losses in activity. In addition, these esters, when mixed with other aromatics, also prolong the fragrance of the aromatics which are not bound in the silicic-acid ester.
Patent AT-E278401-T1 (AT)
Inventor: STUTZMANN JEAN-MARIE
IPC: C07D277/82
Filed: 1999-12-13
Granted: 2004-10-15
Abstract: The invention concerns the use of riluzole or one of its pharmaceutically acceptable salts for preventing and/or treating acoustic traumas and, in particular, different types of deafness and tinnitus.
Patent AT-E224421-T1 (AT)
Inventor: DIETZEN FRANZ-JOSEF
IPC: E04B1/94
Filed: 1999-12-07
Granted: 2002-10-15
Abstract: Flame-retardant foam slabs are based on styrene polymers wherein from 1 to 12% by weight of expanded graphite and also, if desired, from 1 to 12% by weight of a phosphorus compound are present as flame retardants.
Patent DE-06849210-T1 (DE)
Title: Schwenksteife kardanische kipprotornabe
Inventor: STAMPS FRANK B
IPC: B64C27/32
Filed: 2006-01-13
Abstract: Eine
Rotornabe für
einen Drehflügler, welche
Folgendes beinhaltet:  einen Bügel, der eine Vielzahl von
Bügelarmen
aufweist, wobei nebeneinanderliegende Bügelarme durch einen Bügelträger miteinander
verbunden sind und wobei die Bügelarme
und die Bügelträger einen
zentralen freien Bereich begrenzen, der so ausgebildet ist, dass
dieser eine zentrale Welle aufnehmen kann;  mindestens ein Neigungswinkelhorn,
das einen Neigungswinkelhorn-Innenausleger besitzt und einen Neigungswinkelhornarm,
wobei das Neigungswinkelhorn zentral mit dem Bügel verbunden ist und der Neigungswinkelhorn-Innenausleger
im wesentlichen im freien zentralen Bereich angeordnet ist; und  ein
Gleichlaufgelenk, welches ausgebildet ist um Kräfte von der zentralen Welle
auf den Bügel
zu übertragen
und wobei das Gleichlaufgelenk im Wesentlichen in einem zentralen freien
Spalt angeordnet ist.
Patent DE-18162396-T1 (DE)
Title: V-federn, dichtungen mit v-federn und zugehörige verfahren
Inventor: BALSELLS PETER J
IPC: F16J15/3212
Filed: 2018-03-16
Abstract: Dichtungsbaugruppe, umfassend:ein Dichtungselement, das einen Innenflansch mit einer Dichtungslippe, einen Außenflansch mit einer Dichtungslippe und einen mittleren Kanalabschnitt, der einen Federhohlraum definiert, aufweist, wobei sich der Außenflansch in einer ersten Richtung über einen längeren Abstand als der Innenflansch erstreckt;eine V-Feder, die sich in dem Federhohlraum befindet, wobei die V-Feder eine Vielzahl von V-Körpern umfasst, und wobei jeder V-Körper einen langen Schenkel umfasst, der sich in der ersten Richtung über einen längeren Abstand als ein kurzer Schenkel erstreckt; undwobei der kurze Schenkel eine Terminalkante aufweist und wobei der kurze Schenkel gegen eine Innenfläche des Innenflansches vorgespannt ist.
Patent DE-375516-T1 (DE)
IPC: F16H7/12
Filed: 1989-12-14
Abstract: Transmission belt (2) tensioning device with two idlers on an elastic torsion sleeve serving as a swivel axis for the tensioning arm carrying a first idler (5), and as a bearing for a return idler (8), the said device permitting winding angles greater than 180 degrees on each of the receiving pulleys (3) and (4), and reduced tensions in return for the same power-transmission requirements. 
<IMAGE>
Patent DE-773924-T1 (DE)
Inventor: MAURO MARINA
IPC: C07C313/00
Filed: 1996-05-17
Abstract: The present invention refers to a process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride, comprising the reaction in heterogeneous phase between 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid and thionyl chloride, in a solvent selected from the group consisting of: (C7-C16) linear or branched hydrocarbons, (C7-C8) aromatic hydrocarbons, 1,1,1-trichloroethane, n-butylacetate, diglyme (diethylenglycoledimethylether), and in the presence of a catalytic amount of a tertiary amine.
Patent ES-2056779-T1 (ES)
Inventor: YVIN JEAN-CLAUDE
IPC: A01N65/00
Filed: 1992-10-02
Abstract: The subject of the present invention is a process for treating plant-derived products, especially of marine origin. According to the invention, this process consists, in a first stage, in reacting polyvinylpyrrolidone in solution with at least one plant derivative and in then filtering the reaction mixture thus obtained, for example by ultrafiltration, by microfiltration or by filtration through a horizontal-plate filter. This treatment process makes it possible to potentialise the known biological activity of plant-derived products.
Patent ES-2149146-T1 (ES)
Title: Herramienta estilo pico con un inserto de cermet que tiene un ligante co-ni-fe.
Inventor: HEINRICH HANS-WILM
IPC: B25D17/02
Filed: 1998-08-20
Abstract: Herramienta estilo pico que comprende: un cuerpo de herramienta alargado que tiene un extremo axialmente anterior y un extremo axialmente posterior; un inserto duro fijado al cuerpo de la herramienta en el extremo axialmente anterior de la misma; y el inserto duro comprende un cermet WC que contiene carburo de tungsteno y aproximadamente de 5% en peso a 27% en peso de ligante de Co-Ni-Fe comprendiendo aproximadamente de 40 % en peso a 90 % en peso de cobalto, consistiendo el resto de dicho ligante en níquel y hierro y, opcionalmente, las inevitables impurezas, con aproximadamente 4 % en peso a 36 % en peso de níquel, aproximadamente 4 % en peso a 36 % en peso de hierro, y una razón Ni-Fe de aproximadamente 1,5:1 a 1:1,5.
Patent ES-2147173-T1 (ES)
Inventor: DAUTRICHE LEON
IPC: E03F9/00
Filed: 1999-08-10
Abstract: The sewer cleaner comprises a chassis (10) with side beams (12,14) connected by crosspieces (13,15,17,19). At one end are driving wheels (16,18) each driven by an independent motor. Pairs of idling wheels (20-23) at the other end of the chassis rotate in bearings in each side beam. Guide wheels (24-27) with vertical axles arranged along the side beams can roll along the side walls of the sewer. A tool support (33) with a height adjuster (34,36) is fitted with a plate (39) rotating at the end (42) of the support.
Patent CY-1110880-T1 (CY)
Inventor: MASIGNANI VEGA
IPC: G01N33/53
Filed: 2010-11-04
Abstract: The invention provides proteins from  Neisseria meningitidis  (strains A & B) and from  Neisseria gonorrhoeae,  including amino acid sequences, the corresponding nucleotide sequences, expression data, and scrological data. The proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
Patent CY-1116462-T1 (CY)
Title: Περιφερειακοι ανταγωνιστες ληπτη οπιουχου και χρησεις αυτων
Inventor: MELUCCI CHARLES K
IPC: A61P25/36
Filed: 2015-07-02
Abstract: Η παρούσα εφεύρεση παρέχει μία ένωση του τύπου I όπου το Χ-, R 1 και R 2 είναι όπως ορίζονται στην παρούσα, και συνθέσεις αυτής, χρήσιμες σαν περιφερειακός ανταγωνιστής λήπτη οπιούχου μ.
Patent CY-1121072-T1 (CY)
Title: Αντισωματα αντι-ρ-σελεκτινης και μεθοδοι χρησης αυτων στην αντιμετωπιση φλεγμονωδων νοσων
Inventor: MCEVER RODGER P
IPC: C07K16/28
Filed: 2018-11-22
Abstract: Η εφεύρεση χαρακτηρίζει αντισώματα, π.χ., χιμαιρικά και ανθρωποποιημένα αντισώματα, τα οποία αναγνωρίζουν (δηλαδή, προσδένονται) την Ρ-σελεκτίνη. Τα αντισώματα Ρ-σελεκτίνης αναστέλλουν την πρόσδεση της Ρ-σελεκτίνης στο συγγενή υποδοχέα της. Τα αντισώματα Ρ-σελεκτίνης μπορούν να χρησιμοποιηθούν για την αντιμετώπιση φλεγμονωδών και θρομβωτικών καταστάσεων, π.χ. δρεπανοκυτταρική νόσο, κρίση πόνου που σχετίζεται με δρεπανοκυτταρική νόσο, εν τω βάθει φλεβική θρόμβωση, άσθμα, ρευματοειδή αρθρίτιδα, ψωρίαση και βλάβη από ισχαιμία-επαναιμάτωση σε ασθενή που χρήζει αυτών.
Patent CY-1120983-T1 (CY)
Title: Λιμενικη εγκατασταση αποθηκευσης για υγρα καυσιμα
Inventor: BLANCHETIERE GAEL
IPC: E02B3/06
Filed: 2018-12-10
Abstract: Η εφεύρεση αφορά μία λιμενική εγκατάσταση αποθήκευσης για υγρά καύσιμα, εγκατεστημένη πλησίον μίας προβλήτας (2), η οποία σχηματίζεται από τουλάχιστον: - μία άνω επιφάνεια (21) ουσιαστικά παράλληλη προς την ελεύθερη επιφάνεια της θάλασσας (9)˙ - μία πρόσθια επιφάνεια (22) γειτονική προς την άνω επιφάνεια (1) και εν μέρει βυθισμένη. Σύμφωνα προς την εφεύρεση, το στοιχείο (1) είναι στερεωμένο στην προβλήτα (2) δια μέσων αγκύρωσης (3) που συνδέουν μία από τις πλευρικές επιφάνειες (102) του κυτιοειδούς στοιχείου δεξαμενής (10) στην πρόσθια επιφάνεια (22) της προβλήτας (2), όπου η κάτω επιφάνεια (101) και οι πλευρικές επιφάνειες (102) του κυτιοειδούς στοιχείου δεξαμενής (10) είναι τότε τουλάχιστον εν μέρει βυθισμένες.
Patent CY-1122460-T1 (CY)
Title: ΔΙΣΚΙΟ ΠΟΥ ΠΕΡΙΛΑΜΒΑΝΕΙ 7- [4- (4-ΒΕΝΖΟ [b] ΘΕΙΟΦΑΙΝ-4-ΥΛΟ-ΠΙΠΕΡΑΖΙΝ-1-ΥΛΟ)ΒΟΥΤΟΞΥ]-1Η-ΚΙΙΝΟΛΙΝ-2-ΟΝΗ Ή ΑΛΑΣ ΑΥΤΗΣ
Inventor: INOUE YOSHIHARU
IPC: A61K47/02
Filed: 2020-01-08
Abstract: Αυτή η εφεύρεση σχετίζεται με ένα δισκίο που περιέχει, ως δραστικό συστατικό, 7-[4-(4-βενζο[b]θειοφαιν-4-υλο-πιπεραζιν-1-υλο) βουτοξυ]-1Η-κινολιν-2-όνη ή ένα άλας αυτής, που έχει εξαιρετική ικανότητα αποσάθρωσης, σταθερότητα αποθήκευσης και φωτοσταθερότητα. Το δισκίο της παρούσας εφεύρεσης που περιλαμβάνει ένα μη επικαλυμμένο δισκίο που περιέχει 7-[4-(4-βενζο[b]θειοφαιν-4-υλο-πιπεραζιν-1-υλο) βουτοξυ]-1Η-κινολιν-2-όνη ή ένα άλας αυτής ως δραστικό συστατικό, έκδοχα όπως λακτόζη, άμυλο αραβοσίτου και μικροκρυσταλλική κυτταρίνη• αποσαθρωτικά όπως χαμηλής υποκατάστασης υδροξυπροπυλοκυτταρίνη, νατριούχο κροσκαρμελλόζη και νατριούχο καρβοξυμεθυλικό άμυλο• συνδετικά υλικά όπως υδροξυπροπυλοκυτταρίνη• λιπαντικά όπως στεατικό• και που περιλαμβάνει επιπλέον μια στιβάδα επικάλυψης που περιέχει υπρομελλόζη• τάλκη• οξείδιο του τιτανίου• χρωστική• και τα παρόμοια, όπου η στιβάδα επικάλυψης εφαρμόζεται στην επιφάνεια του μη επικαλυμμένου δισκίου.
Patent CY-1124031-T1 (CY)
Title: Ετεροαρυλ υποκατεστημενες πυριδινες και μεθοδοι χρησης
Inventor: ALTENBACH ROBERT J
IPC: C07D413/14
Filed: 2020-07-14
Abstract: Η εφεύρεση αποκαλύπτει ενώσεις του Τύπου (Ι), όπου τα Χ1, Χ2, R1 και R2 είναι όπως ορίζεται στο παρόν. Η παρούσα εφεύρεση αφορά ενώσεις και τη χρήση αυτών στη θεραπεία της κυστικής ίνωσης, μεθόδους για την παραγωγή τους, φαρμακευτικές συνθέσεις που περιλαμβάνουν αυτές και μεθόδους θεραπείας της κυστικής ίνωσης δια χορήγησης μιας ένωσης της εφεύρεσης.
Patent HR-P20100229-T1 (HR)
Title: Therapeutic agents useful for treating pain
Inventor: KYLE DONALD J
IPC: C07D213/74
Filed: 2010-04-20
Abstract: Compounds of formulae (I) and (II) where X is S or O and Ar 2 , R 1 , R 2 , R 3 , R 8 , n, m, and t are disclosed herein, or a pharmaceutically acceptable salt thereof (a "3-substituted Pyridyl Compound"), compositions comprising an effective amount of a 3-substituted Pyridyl Compound, and methods for treating or preventing pain, urinary incontinence, an ulcer, inflammatory-bowel disease, irritable-bowel syndrome, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia or depression in an animal comprising administering to an animal in need thereof an effective amount of a 3-substituted Pyridyl Compound are disclosed herein.
Patent SI-1106666-T1 (SI)
Title: Powder composition and method for polishing stone
Inventor: LUM WING THYE
IPC: C09K3/14
Filed: 2000-11-27
Abstract: The present invention relates to a powder composition and to a method for polishing stone, in particular granite, said method making use of said powder composition.
Patent SI-1341528-T1 (SI)
Title: Rapidly disintegrating tablet comprising an acid-labile active ingredient
Inventor: DIETRICH RANGO
IPC: A61K9/20
Filed: 2001-12-06
Abstract: A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
Patent SI-1862412-T1 (SI)
Title: Device for the transport of goods
Inventor: VAN WASSENHOVE JOHAN MARCEL MAURICE
IPC: B61B1/00
Filed: 2007-05-15
Abstract: Device for the transport of goods, characterised in that it mainly consists of an underground transport system with transport platforms (18) that are mutually connected in a closed circuit and that are continuously moved at an adjustable, but mainly constant speed of rotation, and of at least two loading and unloading terminals (4) that are each provided with intermediary means of transport that can speed up goods to be transported from a standstill to the speed of rotation of the transport platforms (18), whereby the device is also provided with transfer means which make it possible to transfer the goods from the above-mentioned intermediary means of transport to the transport platforms (18) or vice versa.
Patent SI-2061513-T1 (SI)
Title: Method of treating hepatitis c patients
Inventor: ALBRECHT JANICE K
IPC: A61K45/00
Filed: 2008-09-11
Abstract: The application discloses a combination for use in a method of treating patients suffering from hepatitis C infection who are treatment naive or who have relapsed from having a negative HCV status.
Patent SI-2805986-T1 (SI)
Title: Process for the production of nano-fibrillar cellulose gels
Inventor: GANE PATRICK A C
IPC: D21C9/00
Filed: 2009-03-30
Abstract: The present invention relates to a process for the production of nano-fibrillar cellulose gels by providing cellulose fibres and at least one filler and/or pigment; combining the cellulose fibres and the at least one filler and/or pigment; and fibrillating the cellulose fibres in the presence of the at least one filler and/or pigment until a gel is formed, as well as the nano-fibrillar cellulose gel obtained by this process and uses thereof.
Patent SI-2297820-T1 (SI)
Title: Metal protective ground conductor connection device
Inventor: BOCKER MARC
IPC: H01R9/00
Filed: 2009-06-08
Abstract: Protective ground conductor connection device (1) made of a conducting material, in particular a metal, in particular for a terminal strip or an electronic housing, comprising: A base member (2) comprising at least one receptacle (9) for holding a support rail (16); and a spring (11) connected to the base member (2) in an electrically conducting manner, wherein the base member (2) has preferably a U-shaped cross section with a base section (4) and two side sections (5, 6), wherein the base member (2) comprises a contact section - with a line contact area to the support rail -, said contact section being broader than the material thickness of the conducting material and/or having at least the same width of the base section (4).
Patent SI-2613397-T1 (SI)
Title: Automobile battery
Inventor: KIM DAE UNG
IPC: H01M10/00
Filed: 2011-10-20
Abstract: A battery includes anode plates, formed as a mesh by forming cuts in series on a lead plate strip rolled into a uniform thickness, for storing electricity in a chemically reactive state by expansion processing, cathode plates formed as a mesh for storing electricity in a chemically reactive state, separators between the anode and cathode plates for electrical insulation, mechanical separation, and the impregnation of an AGM with electrolyte, such that the chemical reaction for storing electricity is facilitated and the pressure in the cell remains constant, upper and lower cases made of polypropylene and containing the anode plates, cathode plates, separators, and electrolyte in a plurality of mutually separate cells, and a cap coupled into the screw holes formed in the cell units in the upper case, for discharging gas generated during charge and discharge when the pressure of the gas is over a permissible level.
Patent TR-200102309-T1 (TR)
Title: Yönlendirilerek sertleştirilmiş parçaların kaynak tamiri
Inventor: SMASHEY RUSSEL WAYNE
IPC: B23K31/00
Filed: 2000-10-04
Abstract: Yönlendirilerek sertlestirilmis nikel bazinda süper alasimdan bir parçanin sertlesme yönüne (54) paralel uzanan bir hasari (58) vardir. Parça (40) hasarda (58) mevcut herhangi bir yabanci maddenin uzaklastirilmasi ve sonra parçanin (40) temel meteryalin oksidasyonunu engelleyen koruyucu bir gaz içeren bir hücre içerisinde temel materyalin sertlesme isisinin yaklasik yüzde 60'i ile yaklasik yüzde 98'i arasindaki bir tamir isisina çikarilmasiyla tamir edilemektedir. Hasar (58) parça (40) tamir isisinda muhafaza edilirken bir dolgu metaliyle doldurulmaktadir.
Patent TR-201206796-T1 (TR)
Title: Koordinat sensörü ve görüntüleme cihazı.
Inventor: HATA MASAYUKI
IPC: G01B11/00
Filed: 2010-10-26
Abstract: Mevcut buluşa ait koordinat sensörü ışık yayan diyotlar (10) ve hat sensörlarını içermektedir; bunlardan her biri ışık alan elemanlara (13s) sahiptir ve sensör ek olarak ışık yayan diyotlar (10) ve ışık alan elemanların (13s) arasında, ışık yayan diyotlardan (10) yayılan ışığın ışık alan elemanlara (13s) seçilerek gelmesine izin veren, dalga boyu selektif yansıtma aynaları (11) yer almaktadır.
Patent DE-3588224-T2 (DE)
Inventor: CERRETTI DOUGLAS P
IPC: A61P37/00
Filed: 1985-03-13
Granted: 2001-10-25
Abstract: (1)Interleukin 1 (I), as a homogenous protein of molecular wt. about 17500 daltons and having a partial amino acid sequence of formula (II), is new. (2)Homogeneous human interleukin 1 consisting of a single protein species of molecular wt. of about 17500 daltons and having the following amino acid compsn. is new. The compsn. (amino acid and no. of residues/molecule, consists of Asp/Asn 14; Thr 8; Ser 11; Glu/Gln 22; Pro 6; Gly 11; Ala 8; Cys at least 1; Val 11; Met 4; Ile 6; Leu 11; Tyr 4; Phe 11; His 3; Lys 13; Arg 3. (3) Pure DNA encoding for the expression of human (I) molecules is new. (4) Recombinant DNA cloning vector comprising a CDNA sequence comprising the gene for (I) is new. (5)Recombinant DNA cloning vector comprising DNA as claimed in paragraph (3) above is new. (6)Host transformed by a cloning vector as defined in paragraphs (4) and (5) above is new.
Patent DE-3686608-T2 (DE)
Inventor: SCARLATA LUCIO
IPC: A23G9/04
Filed: 1986-05-27
Granted: 1993-03-25
Abstract: A plant for defrosting blocks (14) of frozen or deep-frozen food products, of the type with a flaking roller (10), uses a concentric-tube heat exchanger (52) to thaw the flakes, the heat exchanger having filter plates and a line for recirculating (72) the partially-thawed product to the tank (28) for collecting the flakes and to the exchanger (52) until the product has partially or completely thawed, substantially without thermal gradients within the thawed product.
Patent DE-3752387-T2 (DE)
Inventor: PASTAN IRA
IPC: A61K47/48
Filed: 1987-09-23
Granted: 2006-06-08
Abstract: The present invention relates to various modified forms of Pseudomonas exotoxin exhibiting low toxicity to human or animal cells by itself but retaining its enzymatic activity. The modified Pseudomonas exotoxin of the present invention has ADP ribosylating activity but lacks all or part of domain II (responsible for translocation across cell membrane) of the native toxin. A preferred modified Pseudomonas exotoxin of the present invention further comprises a modification in the receptor binding domain IA of the native Toxin. Conjugates (immunotoxins) comprising a modified Pseudomonas exotoxin and a targeting carrier, such as an antibody or a growth factor, methods for producing a modified Pseudomonas exotoxin or conjugates thereof and compositions suitable for administration to a mammal for achieving targeted cytotoxin activity are also disclosed.