baber/WOPTO huggingface dataset:
Patent CA-2767811-A1 (CA)
Inventor: LIANG YIN
IPC: A61K31/155
Filed: 2010-07-07
Abstract: The present invention is directed to co-therapy and methods for the treatment and prevention of glucose-related disorders such as Type 2 diabetes mellitus and Syndrome X, said methods comprising administering to a subject in need thereof a therapeutically effective amount of co-therapy comprising (a) metformin or a pharmaceutically acceptable salt thereof; and (b) a compound of formula (I). The present invention is further directed to pharmaceutical compositions for the co-therapy of glucose-related disorders.
Patent CA-2767948-A1 (CA)
Inventor: CULLETON PAUL DAVID
IPC: E01C3/00
Filed: 2010-07-13
Abstract: An area suitable for sporting activities comprises an upper synthetic surface layer, and a sub-surface support layer which includes a load bearing structural module. The structural module comprises a top wall and a bottom wall spaced therefrom by one or more supporting elements so as to define a volume between the top and bottom walls. The top wall is provided with a plurality of apertures to permit the flow of liquid into and out of the volume. The size and shape of the apertures is such that the apertures cause substantially no variation in the flatness of the synthetic surface layer.
Patent CA-2768566-A1 (CA)
Inventor: ROYLANCE JAMES MERRILL
IPC: G01D5/20
Filed: 2012-02-16
Abstract: Embodiments of the invention described herein provide a magnetic sensor interface capable of adjusting signal conditioning dynamically such that the true positive and negative peaks of the input signal are maintained for a given target across its entire speed range (0-Max rpm), therefore increasing the signal to noise ratio at low speeds and avoiding clipping or distortion at high speeds. In one aspect, a method comprises receiving an alternating differential voltage signal from a sensor. The alternating differential voltage signal has an amplitude that changes over time. The alternating differential voltage signal is converted to an attenuated single-ended voltage signal that can be dynamically scaled. The attenuated single-ended voltage signal can be scaled by multiplying the attenuated single-ended voltage signal by a scaling factor. The scaling factor is selected relative to a signal-to-noise ratio of the scaled attenuated single-ended voltage signal.
Patent CA-2768588-A1 (CA)
Title: Mobile exercise device
Inventor: WILLIAMS ROB
IPC: A63B23/02
Filed: 2012-02-22
Abstract: A mobile exercise device includes a body and a plurality of glide members. The body includes a pair of parallel ridges defining an elongated rectangular centre portion, wherein respective length and width dimensions of the centre portion are sized to enable a user to stand with one foot positioned longitudinally on the centre portion/  The centre portion further includes a transversally oriented elongated opening sized to receive fingers of a user's hand, to thereby permit a user to grasp the centre portion. The glide members are affixed to the body outboard of the ridges, and facilitate omnidirectional movement of the device across a floor surface. The glide members further define a clearance distance between the centre portion and the floor surface which is larger than an expected thickness of the user's fingers.
Patent CA-2771297-A1 (CA)
Inventor: JACKY BIRGITTE P S
IPC: A61K38/16
Filed: 2010-08-16
Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
Patent CA-2772507-A1 (CA)
Inventor: OPHARDT HEINER
IPC: F04B9/14
Filed: 2012-03-20
Abstract: A piston pump dispenser having a reciprocating piston pump arrangement in which in a dispensing stroke in which fluid is pressurized in a chamber to dispense fluid, a piston slide member is urged into a sealing disc of a piston sleeve member to increase the extent to which the sealing disc provides a seal with a wall of the chamber against fluid leaking out past the seal disc.
Patent CA-2772776-A1 (CA)
Inventor: CASHIN FREDERICK
IPC: B01D3/00
Filed: 2010-08-31
Abstract: A system and process for the recovery of at least one halogenated hydrocarbon from a gas stream. The recovery includes adsorption by exposing the gas stream to an adsorbent with a lattice structure having pore diameters with an average pore opening of between about 5 and about 50 angstroms. The adsorbent is then regenerated by exposing the adsorbent to a purge gas under conditions which efficiently desorb the at least one adsorbed halogenated hydrocarbon from the adsorbent. The at least one halogenated hydrocarbon (and impurities or reaction products) can be condensed from the purge gas and subjected to fractional distillation to provide a recovered halogenated hydrocarbon.
Patent CA-2778826-A1 (CA)
Title: Amphiphilic drug-oligomer conjugates with hydrolyzable lipophile components and methods for making and using the same
Inventor: EKWURIBE NNOCHIRI
IPC: A61K38/00
Filed: 2000-06-19
Abstract: The present invention relates generally to hydrolyzable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates, and to methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG, and oleic acid can be orally administered.
Patent CA-2779041-A1 (CA)
Inventor: GLICK GARY D
IPC: A61P37/06
Filed: 2006-11-01
Abstract: The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides novel 1,4--benzodiazepine-2,5-dione compounds, and methods of using novel 1,4-benzodiazepine-2,5--dione compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.
Patent CA-2780147-A1 (CA)
Inventor: FERRARI PAUL
IPC: G01B5/012
Filed: 2010-11-05
Abstract: An articulated arm CMM comprises a plurality of transfer members, a plurality of articulation members connecting at least two transfer members to each other, a coordinate acquisition member at a distal end, and a base at a proximal end. At least two of the articulation members can include at least one encoder and the at least two encoders can both be enclosed within a single monoblock housing.
Patent CA-2781537-A1 (CA)
Title: Recombinant filaggrin polypeptides for cell importation
Inventor: STOUT TIMOTHY J
IPC: A61K38/17
Filed: 2010-11-22
Abstract: Disclosed are recombinant polypeptides that include (a) a f?laggrin amino acid sequence and (b) a cell importation signal sequence that includes a motif of two to fifteen amino acids, wherein the motif includes at least one arginine residue and at least one methionine residue. Also disclosed are nucleic acids encoding the recombinant polypeptides of the present invention, and compositions that include the recombinant polypeptides and nucleic acids of the present invention. Methods of treating or preventing a skin disease or skin disorder using the compositions of the present invention are also included, as well as kits that include a sealed containing that includes a recombinant polypeptide of the present invention.
Patent CA-2784279-A1 (CA)
Title: Halogen-free flame retardant compositions
Inventor: CHEN JING GIVEN
IPC: C08L75/04
Filed: 2009-12-18
Abstract: The present disclosure provides a flexible, halogen-free, flame retardant composition. The composition includes from about 25 wt % to about 95 wt % of a thermoplastic polyurethane (TPU); from about 5 wt % to about 50 wt % of an olefin block copolymer (OBC); and from about 30 wt % to about 70 wt % of a flame retardant. The flame retardant is selected from resorcinol bis(diphenyl 5 phosphate) (RDP), bis diphenyl phosphate (BDP), bisphenol-A bis(diphenyl phosphate) (BPADP), aluminum trihydrate (ATH), a nitrogen/phosphorus-based halogen-free flame retardant, epoxidized novolac resin, and combinations thereof. The composition requires no compatibilizer for the TPU and OBC. The composition finds application in wire and cable structures.
Patent CA-2785656-A1 (CA)
Title: Tool for diagnosis and prognosis of mature b-cell neoplasms
Inventor: HOULDSWORTH JANE
IPC: C12Q1/68
Filed: 2010-12-29
Abstract: The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers, particularly mature B-cell neoplasms. The invention further provides methods of diagnosing and providing prognosis certain types of cancer, particularly mature B-cell neoplasms. The methods can comprise contacting a sample to a microarray according to the invention, allowing any genetic material in the sample to hybridize to the genomic regions on the microarray, analyzing the hybridizations, and correlating the hybridizations to certain cancer types, particularly mature B-cell neoplasms.
Patent CA-2788467-A1 (CA)
Title: Electronic payment processing method and system with smart/authenticate fields and definitions
Inventor: ROCHE MICHAEL
IPC: G06Q20/00
Filed: 2011-01-28
Abstract: A method and corresponding system for supporting authentication processing of commercial transactions conducted over a communications network between consumers and merchants. Payment information for a commercial transaction between a consumer and a merchant is received over the communications network. The payment information identifies a payment instrument supporting an authenticated payment program. A determination is made as to whether to authenticate the consumer using the authenticated payment program based on authentication criteria defined by the merchant. The consumer is authenticated over the communications network in accordance with the authenticated payment program if authentication is determined to be appropriate based on the authentication criteria defined by the merchant.
Patent CA-2788527-A1 (CA)
Inventor: NISHIOKA KUSUKI
IPC: A61K39/395
Filed: 2011-01-27
Abstract: Provided is a pharmaceutical composition which is used in the treatment or prevention of early-stage osteoarthritis. Also provided is a method for producing same. The pharmaceutical composition and method of production therefor are based on the knowledge that it is possible to use IgM anti-Fas antibodies to alleviate the symptoms of osteoarthritis. Specifically, the pharmaceutical composition and method of production therefor are based the pharmaceutical composition is based on the knowledge that it is possible to use IgM anti-Fas antibodies to suppress the production of enzymes that breakdown the cartilage matrix. The pharmaceutical composition and method of production therefor are based on the knowledge that it possible to use IgM anti-Fas antibodies to improve cartilage matrix production.
Patent CA-2790563-A1 (CA)
Title: Cationic electrodepositable coating composition comprising lignin
Inventor: FENN DAVID R
IPC: C08H7/00
Filed: 2010-12-15
Abstract: A cationic electrodepositable coating composition is disclosed.
Patent CA-2791668-A1 (CA)
Inventor: HANAKAWA MASAYUKI
IPC: C12P19/14
Filed: 2011-02-07
Abstract: Provided is a method for removing, during a step for producing a sugar solution, a fermentation inhibiting substance, which is generated during a step for producing sugar from a cellulose-containing biomass. Also provided is a method for steadily generating a pure sugar solution, which has an extremely low content of a fermentation inhibiting substance, over a long period of time. Specifically, disclosed is a method for producing a pure sugar solution, which uses a cellulose-containing biomass as the starting material and which involves: a step (1) for producing a sugar solution by subjecting a cellulose-containing biomass to decomposition treatment; a step (2) for subjecting the sugar solution obtained in step (1) to coagulation treatment; a step (3) for filtering the sugar solution obtained in step (2) by means of a microfiltration membrane and/or an ultra-filtration membrane, and for collecting the sugar solution from the permeate side; and a step (4) for filtering the sugar solution obtained in step (3) by means of a nano-filtration membrane and/or a reverse osmosis membrane, for collecting the pure sugar solution from the non-permeate side, and for removing a fermentation inhibiting substance from the permeate side.
Patent CA-2795827-A1 (CA)
Inventor: COOKE CHARLES BRIAN DURLER
IPC: A47J41/00
Filed: 2011-04-18
Abstract: A thermal storage device (1) for storing and maintaining a body (5), such as liquid, at a constant storage temperature different to a temperature external (1') to such device, comprises: a container (4) for containing this body at the constant storage temperature; and a thermal source (3) for compensating heat transfer resulting from a thermal gradient between the external temperature and the constant storage temperature. The thermal source comprises a mass (31) for accumulating thermal energy and for transferring heat from or to the container to compensate said heat transfer resulting from the thermal gradient and maintain the body at the constant storage temperature.
Patent CA-2798279-A1 (CA)
Title: Dynamic ambient lighting
Inventor: COOK MICHAEL J
IPC: F21S4/10
Filed: 2012-12-07
Abstract: Systems, methods, software, and data structures that provide dynamic ambient lighting synchronized to a video program being watched in a premise are described herein. A video program may be associated with a predefined lighting scheme that specifies or identifies a time sequenced set of lighting effects (e.g., flashing police lights, sunrise, explosion, etc.) that are to be performed by the dynamic ambient lighting system time-synchronously with the video program. Components of the dynamic ambient lighting system may extract the lighting scheme from video data, parse the lighting scheme into individual lighting effects, and then control a single-color or multicolor light source associated with each of a plurality of light channels (e.g., front right, rear right, front left, rear left, center, and burst channel, among others) based on time sequenced lighting primitives defined by each lighting effect. Light sources may be wirelessly controlled, e.g., using an IEEE 802.15.4 or ZigBee-compliant wireless system.
Patent CA-2798490-A1 (CA)
Title: Nitrogen heterocyclic compounds useful as pde10 inhibitors
Inventor: ALLEN JENNIFER R
IPC: A61K31/4439
Filed: 2011-05-11
Abstract: Unsaturated nitrogen heterocyclic compounds of formula (I): (I), as defined in the specification, compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, Huntington's Disease, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Patent CA-2799530-A1 (CA)
Inventor: NAFTALI PHILIP
IPC: A44B18/00
Filed: 2011-05-12
Abstract: A magnetic sealing closure, comprising: a. a first flexible strip, with a plurality of cavities adapted to incorporate a plurality of magnetic elements; b. a second flexible strip, with a plurality of cavities adapted to incorporate a plurality of magnetic elements; wherein said sealing closure comprises membranes connectable to said first strip, and a second membrane connectable to said second strip, such that said plurality of magnetic elements of said second strip are embedded within said plurality of cavities between said second strip and said second membrane; when said first and second strips and are brought together from the side of said first and second membranes, magnetic elements of said first and said second strips magnetically attract each other, such that a sealing is provided.
Patent CA-2800689-A1 (CA)
Title: Assembly, and associated method, for controlling disposition of enterprise data at a wireless device
Inventor: HOLLERAN JEFFREY J
IPC: H04W12/08
Filed: 2011-05-27
Abstract: An apparatus, and an associated method, facilitates enterprise control of enterprise data at a personal - liable wireless device (14). A network -generated command, generated by a network command generator (62) is sent to the wireless device. The command is detected at the wireless device, and the contents of the detected command are ascertained. The affected data is accessed, and disposition is made of the affected, enterprise data.
Patent CA-2800841-A1 (CA)
Inventor: PIECZYKOLAN JERZY SZCZEPAN
IPC: C07K14/435
Filed: 2011-06-24
Abstract: The fusion protein, especially recombinant, comprising domain (a) which is a functional fragment of soluble hTRAIL protein sequence beginning with an amino acid at a position not lower than hTRAIL95 or a sequence having at least 70% homology thereto; and domain (b) which is a sequence of pro-apoptotic effector peptide, wherein the sequence of domain (b) is attached at C- terminus and/or N - terminus of domain (a). The fusion protein has anticancer activity. The nucleotide sequence coding the fusion protein, expression vector and host cell for the preparation of the fusion protein, and the use of the fusion protein for treating cancer diseases.
Patent CA-2802179-A1 (CA)
Inventor: PERRON CHRISTIAN Y
IPC: A61F5/00
Filed: 2011-06-08
Abstract: An implantable system comprises a housing that includes a flexible reservoir. The flexible reservoir is coupled to an inflatable portion of a gastric band via a fluid inlet/outlet. The flexible reservoir contains a fluid and has an expanded configuration and a contracted configuration. An access port may be coupled to the flexible reservoir and/or the gastric band to facilitate filling and draining the reservoir and/or the gastric band. A movable wall is slidably positioned around the flexible reservoir to move the flexible reservoir between the expanded configuration and the contracted configuration to move the fluid into and out of the inflatable portion of the gastric band. A driving mechanism is positioned around the movable wall and is capable of changing the size of the movable wall to compress or expand the flexible reservoir. A motor, coupled to the driving mechanism, may actuate the driving mechanism.
Patent CA-2802226-A1 (CA)
Inventor: KENNEDY MARC ADAM
IPC: H04N5/30
Filed: 2013-01-16
Abstract: Apparatus and methods of manufacturing an image sensor and inertial navigation sensors encapsulated within a single package. The single package may encapsulate one integrated circuit die comprising the imaging sensor and the inertial navigation sensors. Alternatively, the single package may encapsulate a plurality of integrated circuit dice comprising the imaging sensor and the inertial navigation sensors.
Patent CA-2803002-A1 (CA)
Inventor: ABBASI ARIF
IPC: B62D33/027
Filed: 2011-06-22
Abstract: A vehicle compartment (20) closure apparatus (10) is provided. The closure apparatus includes a frame member (18) and a door (14). The frame member is cofigured to be operable coupled to the vehicle contiguous with the compartment. The frame memberis further configured to be operable coupled to a plurality of single and dual door configurations. The door is coupled to the frame member. At a first operational mode, the door and the frame member are rotatable about a first axis (48) between an open position and a closed position. At a second operational mode, the door is rotatable about a second axis (34) between an open position and a closed position, and the frame member does not move with the door.
Patent CA-2803332-A1 (CA)
Title: Personal electronic target vision system, device and method
Inventor: NOHARA TIMOTHY J
IPC: H04L12/16
Filed: 2013-01-23
Abstract: A personal electronic target vision system displays dynamic targets in real-time to one or more users relative to each user's respective location and field of view in an orientation analogous to unaided human vision. A user's personal electronic vision device (PEVD) exchanges target selection information to a target vision server which returns the corresponding selected target location information to the PEVD for rendering to the user in accordance with the user's changing viewpoint. The target vision server queries a target information server in order to access, filter and provide the required real-time target location information. A surveillance system, consisting of any number and types of sensors and target tracking systems which are separate from and independent of the users, provide the target information server with target location information.  System elements can reside in the Cloud and the PEVD can be implemented as an application on a mobile device.
Patent CA-2806792-A1 (CA)
Inventor: KLOOSTER JOEL KENNETH
IPC: G05D1/04
Filed: 2013-02-14
Abstract: A method of flying an aircraft, where the aircraft has an associated performance envelope, along a flight path based determining an altitude profile for a cruise-climb along the flight path based on the performance envelope of the aircraft and flying the aircraft along the flight path to approximate the altitude profile.
Patent CA-2808577-A1 (CA)
Title: Anti-ngf antibodies and their use
Inventor: BARBON JEFFREY A
IPC: C07K16/22
Filed: 2011-08-19
Abstract: The present disclosure encompasses NGF binding proteins, specifically to antibodies that are chimeric, CDR grafted and caninized antibodies, and methods of making and uses thereof. The antibodies, or antibody portions, of the disclosure are useful for detecting NGF and for inhibiting NGF activity, e.g., in a mammal subject suffering from a disorder in which NGF activity is detrimental.
Patent CA-2808614-A1 (CA)
Inventor: HAYNES CHARLES C
IPC: F03B13/14
Filed: 2013-03-11
Abstract: A point absorber actuates reciprocating motion in at least two motion converters, each for converting linear motion of a respective reciprocating member to rotational motion; said reciprocating members being configured to reciprocate up and down in unison under wave action; each of said motion converters being configured to actuate rotation of a respective rotating member; a first one of said respective rotating members actuating rotation of a shaft in one direction during an up cycle of said reciprocal motion; and, a second one of said respective rotating members actuating rotation of said shaft in said one direction during a down cycle of said reciprocal motion with tidal compensator to maintain point absorber in waves. .
Patent CA-2808698-A1 (CA)
Title: Fuel station and method
Inventor: NIEUWSTRATEN JAN HENDRIK
IPC: B60S5/02
Filed: 2011-09-09
Abstract: The present invention provides a fuel station and a method of refueling a vehicle using said fuel station. The fuel station (430) comprises at least two adjacent base structures (52, 54), each base structure being arranged on a ground surface. Each base structure is provided with a first fuel dispensing device (50) arranged on the respective base structure and defining a first refueling position (58) on a first side (60) of the base structure, and a second refueling position (62) on a second side (64) of the base structure, the second side being opposite to the first side. Each base structure is also provided with a second fuel dispensing device (78) arranged on the respective base structure and defining a third refueling position (78). The fuel station comprises at least one queuing position (122, 124) in front of one of the base structures. Guide means (102, 104) link each queuing position to the first refueling position and to the third refueling position of said one of the base structures, and to the second refueling position on an adjacent base structure.
Patent CA-2808904-A1 (CA)
Inventor: BLACKBURN ANTHONY C
IPC: A61P3/04
Filed: 2011-08-31
Abstract: Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management.