baber/WOPTO huggingface dataset:
Patent AU-2020284114-A1 (AU)
Title: Concurrent activation of regenerative and tolerogenic processes by fibroblast-based compositions for the treatment of multiple sclerosis
Inventor: O'HEERON PETE
IPC: A61K31/4365
Filed: 2020-05-29
Abstract: Described are means, methods, and compositions useful for treatment of multiple sclerosis through the utilization of fibroblasts and/or derivatives thereof to concurrently stimulate regenerative processes while inducing a protolerogenic immune modulatory program. In certain embodiments, fibroblasts are selected for the concurrent properties of immune modulation and regeneration by enrichment for CD73 expressing fibroblasts. In particular embodiments, stimulation of regeneration implies activation of endogenous neural progenitor cells. In some embodiments, stimulation of regeneration implies induction of remyelination. The utilization of fibroblasts as a superior source for immune modulation, prevention of immune mediated pathology, and activation of T regulatory cells is provided within the context of multiple sclerosis.
Patent AU-2020310854-A1 (AU)
Title: Methods for treating and for inhibiting progression of seizures
Inventor: BURSTEIN RAMI
IPC: A61K38/48
Filed: 2020-07-06
Abstract: Methods for treating seizures and for inhibiting progression of a focal seizure to a generalized seizure by administering extracranially a Clostridial derivative are described.
Patent AU-2020315498-A1 (AU)
Title: Device for limiting or keeping constant a flowing quantity of liquid
Inventor: VAN DER UPWICH STIJN
IPC: F15D1/02
Filed: 2020-07-10
Abstract: Flow-limiting element (100) for limiting the flow of a fluid flowing therethrough, comprising a housing (1) provided with an inlet (2), an outlet (3); and a resilient plate-like valve element (4) which is arranged in the housing (1) and which is movable to and from a valve seat (9), defining a throughflow opening (11) therebetween, under the influence of a pressure of the fluid flowing therethrough and is arranged to adjust the size of the throughflow opening (11); wherein the valve seat (9) is arranged with a protruding member (113), having a footprint and a height, for limiting the movement of the resilient plate-like valve element (4) towards the valve seat (9), wherein the protruding member (113) comprises an engagement surface for engaging the resilient plate-like valve element (4), wherein the engagement surface is at least partially curved, wherein a radius of curvature of the at least partially curved engagement surface is equal to, or larger than, a smallest dimension of the footprint of the protruding member (113).
Patent AU-2020328931-A1 (AU)
Title: Antibodies against ILT2 and use thereof
Inventor: MANDEL ILANA
IPC: C07K16/28
Filed: 2020-08-12
Abstract: The present invention provides monoclonal antibodies, or antigen-binding portions thereof, against ILT2, as well as pharmaceutical compositions comprising same and methods of producing same. Also provided are methods of treating cancer comprising administering the antibodies or compositions of the invention. Methods of treating cancer, combination treatments, and patient selection are also provided.
Patent AU-2020357904-A1 (AU)
Title: Fire suppression apparatus
Inventor: MALEWSKI MATTHEW
IPC: A62C13/00
Filed: 2020-09-29
Abstract: A fire suppression apparatus (100) according to an embodiment of the present invention is of a type used particularly in fire suppression systems of vehicles and comprises a container in the form of a pressure cylinder (120) having a discharge valve (130) and, inside the cylinder, a tubular discharge conduit (140). The cylinder (120) is shown in its operable configuration, arranged on its side, and the discharge tube includes a first portion (140a), close to the valve (130), that extends substantially parallel with a longitudinal axis of the cylinder, and in this example is substantially central with respect to the cylinder. The tube also includes a second portion (140b) that extends downwardly from the substantially axial first portion (140a) towards the lowest part of the sidewall of the cylinder and a third portion (140c) that is again substantially parallel with the longitudinal axis of the cylinder, but close to the sidewall of the cylinder, at an insert portion (140d).
Patent AU-2020370530-A1 (AU)
Title: Method of repairing a bearing bore and bore insert for repairing a bearing bore
Inventor: ANDERSEN MOGENS E
IPC: F03D80/70
Filed: 2020-10-02
Abstract: The present invention provides a method of repairing a bearing bore defined by an inner surface of a bearing housing, for instance a bearing housing that is part of a wind turbine. The method includes applying a liquid resin to at least part of the inner surface of the bearing housing. The method includes mounting a bore insert in the bearing bore, where the bore insert includes an arcuate portion having an edge positioned along a line of required radius of the bearing bore, so that the liquid resin fills a gap between the inner surface of the bearing housing and the edge of the arcuate portion of the bore insert. The method includes removing the bore insert from the bearing bore after the liquid resin has solidified to repair the bearing bore to the required radius. Advantageously, the invention provides a relatively simple and inexpensive method for repairing a bearing bore that has suffered wear, that may be performed on-site and which obviates the need for potentially expensive component replacement of the bearing housing.
Patent AU-2020375914-A1 (AU)
Title: CD73 inhibitors
Inventor: DU XIAOHUI
IPC: A61P31/12
Filed: 2020-10-29
Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.
Patent AU-2020398336-A1 (AU)
Title: A dispenser and method of dispensing
Inventor: BOGATEZ EDWIN
IPC: B65D83/00
Filed: 2020-11-30
Abstract: A dispenser (10, 40) for a semi-solid personal product (34) in the form of a cake (13, 63, 83) is disclosed. The dispenser has a base (11, 41) and a lid (12, 44) for the base, the lid and base being dimensioned to receive the cake between the lid and the base. The lid includes at least one orifice (21). The lid and base are threadably inter- engaged (16, 26, 46, 47) to releasably retain the lid on the base and to permit relative rotation between the lid and base to decrease the available volume therebetween. In this way the semi-solid product is extruded via the lid orifice(s). Various refills (36, 60, 80, 90, 99) are also disclosed.
Patent WO-2021163756-A1 (WO)
Title: A protective device for use during surgery
Inventor: GERGES BASSEM
IPC: A61B90/00
Filed: 2021-02-18
Abstract: A protective assembly for use during laparoscopic surgery, the assembly comprising: a thin membrane formed from non-toxic material, the membrane being sufficiently thin and maneuverable to be passed through a cannula of a trocar; a flexible connector extending from the thin membrane; and an insertable shaft dimensioned to be passed through the cannula wherein a distal portion of the shaft is anchored to the flexible connector.
Patent WO-2022036393-A1 (WO)
Inventor: SPOONER-HART ROBERT
IPC: A01P7/04
Filed: 2021-08-17
Abstract: The present invention provides a γ-pyrone compound for use as an insecticide. The γ-pyrone is of the general Formula (I): wherein: R1, R2, R3 and R4 are each independently selected from an optionally substituted C1-C12 alkyl, preferably C1-C6 alkyl, more preferably C1-C2 alkyl; H; -COOH; -OH; -OCH3 or -R5(CH2)nR6R7CH3; R5, R6, and R7 are each independently selected from an optionally substituted C1-C12 alkyl, preferably C1-C6 alkyl, more preferably C1-C2 alkyl; -C=0; -COO-, N, S or O; and n is 1 to 18, a salt, solvate, dimer or isomer thereof. Other embodiments of the invention define use of the γ-pyrone compounds, insecticidal composition comprising the compound thereof and commercial embodiments include kits for on-the-shelf sale.
Patent AU-2021200412-A1 (AU)
Title: Bispecific proteins and methods for preparing same
Inventor: KIM HOEON
IPC: C07K16/46
Filed: 2021-01-22
Abstract: The present invention relates to a bispecific protein and a method preparing the same, 
wherein mutation is introduced into heavy chains and/or light chains to enhance 
heterodimerization between a heavy chain (CH3 domain or Fc) and a heavy chain (CH3 domain 
or Fc) and dimerization between a heavy chain (CHI domain) and a light chain, both targeting 
the same material, thereby constructing heterodimeric bispecific proteins of high purity. A 
bispecific protein according to the present invention can find applications in a variety of fields 
comprising cancer therapy, singling regulation, diagnosis, etc.
Patent AU-2021202440-A1 (AU)
Title: Biodegradable and/or edible tableware
Inventor: CASHMORE STEPHEN ROLAND
IPC: A21D8/06
Filed: 2021-04-21
Abstract: Described is a method of forming a biodegradable and/or edible tableware that has a 
three dimensional shape in a two-step cooking process by first partially cooking a dough, 
that contains at least a flour and gelling agent, in a mould (subject to pressure and heat) 
and then baking the moulded tableware.
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Patent AU-2021204103-A1 (AU)
Title: Compositions and methods of preparing airway cells
Inventor: NIKLASON LAURA
IPC: A61P11/00
Filed: 2021-06-18
Abstract: The present invention provides compositions and methods of preparing airway cells. In one 
aspect, an epithelial airway cell derived from an induced pluripotent stem (iPS) cell 
characterized by expression of airway cell surface markers and an ability to proliferate is 
described. In another aspect, methods of differentiating an iPS into an epithelial airway cell is 
provided. Engineered lungs, methods of making such engineered lungs comprising the 
epithelial airway cells and treating respiratory disorders are also disclosed.
Patent AU-2021204170-A1 (AU)
Title: Platform agnostic systems and methods for building management systems
Inventor: NADUMANE VENUGOPALA KILINGAR
IPC: G05B15/02
Filed: 2021-06-21
Abstract: Devices, methods, and systems for controlling a plurality of devices and equipment 
installed at a building. A system or common model of the devices and equipment at the building 
may be accessible by a technician during setup of a BMS for a building. The system model may 
enforce standardized device names and standardized point names that may be hardware agnostic 
for the plurality of devices and equipment installed at the building. A gateway in 
communication with the installed devices and equipment, along with a computing device storing 
the system model, may receive point information from the installed devices and equipment and 
convert the received point information into hardware agnostic point information. The gateway 
may receive hardware agnostic control commands from the system model and convert the 
hardware agnostic control commands into hardware specific control commands.
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Patent AU-2021204276-A1 (AU)
Title: Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
Inventor: BURK MARK J
IPC: C12P7/44
Filed: 2021-06-24
Abstract: The invention provides a non-naturally occurring microbial organism having a 6
aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway. The 
microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the 
5 respective 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway.  
The invention additionally provides a method for producing 6-aminocaproic acid, caprolactam, 
hexametheylenediamine or levulinic acid. The method can include culturing a 6-aminocaproic 
acid, caprolactam or hexametheylenediamine producing microbial organism, where the 
microbial organism expresses at least one exogenous nucleic acid encoding a 6-aminocaproic 
0 acid, caprolactam, hexametheylenediamine or levulinic acid pathway enzyme in a sufficient 
amount to produce the respective product, under conditions and for a sufficient period of time to 
produce 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid.
Patent AU-2021206775-A1 (AU)
Title: Power assist module for roller shades
Inventor: HAARER STEVEN R
IPC: A47H1/00
Filed: 2021-07-19
Abstract: A power assist module for use in roller tube driven products, such as roller shades. The 
module may be pre-wound prior to installation in a roller tube and retains its pre-wound 
condition, even after use, when removed from the roller tube.  
FIG.1
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Patent AU-2021229249-A1 (AU)
Title: A sealing ring
Inventor: PAYNE GARY
IPC: F16J15/324
Filed: 2021-09-10
Abstract: This disclosure relates to a sealing assembly for use with a rotating shaft. The sealing 
assembly comprises a housing cover and a sealing ring mountable on the rotating shaft and 
rotatable with the shaft. The sealing ring comprises an annular sleeve defining external and 
internal ends. At the external end, the ring has a flange which extends back towards the internal 
end and is flexible to maintain contact with a first sealing surface of the housing cover. At the 
internal end, the ring has a flange having a distal end which extends towards a second sealing 
surface and is flexible to maintain contact with the second sealing surface. The first sealing 
surface and the second sealing surface each have a curved axial cross-section to flex the 
respective first flange and second flange over a range of angular misalignment of the rotating 
shaft to maintain contact to the first sealing surface and the second sealing surface.
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Patent AU-2021236277-A1 (AU)
Title: Guide bar assembly
Inventor: PATEL PRUTHVISH
IPC: B01F27/25
Filed: 2021-03-10
Abstract: The invention relates to a guide bar assembly for a submersible machine, comprising at least two guide bar holders (2) and a guide bar (3) connected to said at least two guide bar holders (2). The guide bar assembly is characterized in that the guide bar assembly (1) further comprises a support column (4), wherein said at least two guide bar holders (2) are connected to the support column (4), the support column (4) being configured to be lowered into a tank (5) and comprising a bracket (6) configured for attachment of the support column (4) to a fixed element arranged at an upper area of said tank (5).
Patent AU-2021247931-A1 (AU)
Title: Flooring element
Inventor: THOMAS RICHARD
IPC: E04F15/02
Filed: 2021-10-11
Abstract: Flooring Element 
5 A flooring element suitable for connection to other elements in a flooring system. The 
flooring element comprises a body, a female connector and a retainer. The body defines a 
connector surface that is horizontal when in use. The female connector comprises a 
connector recess which is suitable for receiving a male connector and also which defines a 
connector opening in the connector surface. The retainer is connectable to the body such 
10 that, while it is connected to the body, the retainer is movable between and open position 
and a closed position. When in the closed position, the retainer is arranged to restrict 
movement of the male connector to guard against the male connector exiting the connector 
recess through the connector opening. When in the open position, the retainer does not 
restrict movement of the male connector thereby permitting the male connector to exit the 
15 connector recess through the connector opening.  
[Figure 2]
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Patent AU-2021272478-A1 (AU)
Title: A system and method for management of access to customer data
Inventor: BAGADIA MAULIK BIPIN
IPC: G06F21/33
Filed: 2021-04-06
Abstract: A system and method for management of access to customer data is provided. The system includes a communication device of the customer and an application server. The communication device receives credentials of the customer. The application server generates a communication link with the communication device and a profile of the customer is created at a storage unit and a unique anonymous ID is appended to the same. In the event, a future service provider requests for access to customer data, the credentials are appended to the profile at the application server received from the communication device for a pre-determined time period and a secure channel is generated between the future service provider communication device and the application server to allow the future service provider to access the customer data. The secure channel is terminated and the appended credentials to the profile is erased, thereby maintaining anonymity of the customer.
Patent AU-2021282467-A1 (AU)
Title: AR+ breast cancer treatment methods
Inventor: HATTERSLEY GARY
IPC: C07D413/10
Filed: 2021-12-08
Abstract: AR+ BREAST CANCER TREATMENT METHODS 
ABSTRACT 
A method for treating AR+ breast cancer in a subject comprising administering to the subject an 
AR agonist (e.g., SARMs such as RAD 140), or in combination with one or more therapeutic 
agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k 
inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
Patent AU-2021282533-A1 (AU)
Title: Optimized crispr/cas9 systems and methods for gene editing in stem cells
Inventor: Gori Jennifer Leah
IPC: C12N15/87
Filed: 2021-12-10
Abstract: The methods and compositions described herein surprisingly increase CRISPR/Cas
mediated gene editing in stem cells by transiently treating the cells with a stem cell viability 
enhancer prior to and/or after contacting the cells with one or more CRISPR/Cas9 
components. Further, this treatment also surprisingly results in increased engraftment of the 
stem cells into the target tissue of a subject. The present disclosure also provides one or more 
modified CRISPR/Cas9 components which, when used in combination with the stem cell 
viability enhancer, further increases the frequency of gene editing in stem cells, increases 
stem cell viability, and increases stem cell engraftment.
Patent AU-2021288458-A1 (AU)
Title: Designed antibody-bound nanoparticles
Inventor: DIVINE ROBERT
IPC: C07K16/28
Filed: 2021-06-07
Abstract: Polypeptides are disclosed comprising an (Fc) binding domain, a helical polypeptide monomer, and an oligomer domain, polymers thereof, and uses thereof.
Patent AU-2021291056-A1 (AU)
Title: N-linked macrocyclic 7-(pyrazol-5-yl)-indole derivatives as inhibitors of MCL-1
Inventor: ROMBOUTS FREDERIK JAN RITA
IPC: C07D515/22
Filed: 2021-06-18
Abstract: The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.
Patent AU-2021312306-A1 (AU)
Title: Agrochemical combinations
Inventor: WAGH PRADIP DATTATRAY
IPC: A01N47/24
Filed: 2021-07-23
Abstract: A plant propagation material treatment combination contains azoxystrobin; at least one benzimidazole fungicide; and at least one neonicotinoid insecticide, wherein the combination does not contain fipronil. The combination or a composition containing the combination can be applied to a plant propagation material before sowing to improve vigour or yield of a plant or to control soil borne fungi and insect pests.
Patent AU-2021359640-A1 (AU)
Title: Vibrating screen control arrangements
Inventor: TEYHAN DOUGLAS ROBERT
IPC: H02K7/065
Filed: 2021-10-15
Abstract: The specification discloses a vibratory screening apparatus for screening mined ore materials utilizing elliptical vibration, the apparatus having a static section, a dynamic section including a screening deck, the apparatus having three pairs of rotary motion exciter cells positioned with a first group of three said rotary motion exciter cells on a first side of the dynamic section and a second group of three said rotary motion exciter cells on a second side of the dynamic section, each of the cells in said first group forming a pair with a respective one of the cells in the second group, the apparatus further including drive means for rotationally driving the cells, and mechanical synchronisation means linking rotation of a first said pair to a second said pair of the cells whereby, in use, rotation of said pairs of cells are mechanically synchronised.
Patent AU-2021376225-A1 (AU)
Title: Variant adeno-associated virus (aav)capsid polypeptides and gene therapeutics thereof for treatment of hearing loss
Inventor: PENNOCK STEVEN
IPC: C07K14/015
Filed: 2021-11-05
Abstract: Described herein are variant adeno-associated virus (AAV) capsid polypeptides and gene therapeutics thereof for use in the treatment or prevention of hearing loss.
Patent AU-2021413871-A1 (AU)
Title: Coupleable, unmanned ground vehicles with coordinated control
Inventor: SMITH FRASER M
IPC: B62D55/06
Filed: 2021-12-30
Abstract: A robotic system comprises a first robotic crawler having a mobility mechanism for locomotion, a second robotic crawler having a mobility mechanism for locomotion, and at least one coupling mechanism supported by at least one of the first or second robotic crawlers to couple and uncouple the first and second robotic crawlers to and from each other. When coupled together, the first and second robotic crawlers are operable as a unified robotic crawler system in a coordinated drive mode for operational control of respective mobility mechanisms in a coordinated manner. Various operating modes provide for selective control of various aspects of the first and second robotic crawlers, whether coordinated or independent control. The unified robotic crawler system provides greater or enhanced stability of the first and second robotic crawlers. Associated methods are provided herein.
Patent AU-2021418328-A1 (AU)
Title: Turbine fracturing system, controlling method thereof, controlling apparatus and storage medium
Inventor: MAO ZHUQING
IPC: F02C9/42
Filed: 2021-06-17
Abstract: A turbine fracturing system, comprising: N turbine fracturing apparatuses, wherein each of the N turbine 
fracturing apparatuses comprises a turbine engine, and N is an integer greater than or equal to 2; a fuel gas 
supply apparatus connected to N turbine engines, wherein the fuel gas supply apparatus is configured to 
supply fuel gas and distribute the fuel gas to the N turbine engines as gaseous fuel; and a fuel liquid supply 
apparatus connected to at least one of the N turbine engines and configured to supply liquid fuel to at least 
one of the N turbine fracturing apparatuses in a case that at least one of a flow rate and a pressure of the 
fuel gas decreases.
Patent AU-2021430413-A1 (AU)
Title: Method for commissioning a door system
Inventor: OBERSTE-UFER KAI
IPC: G07C3/00
Filed: 2021-08-19
Abstract: The invention relates to a method (200) for starting up a door system (60, 61, 62), wherein the door system (60, 61, 62) has multiple door components (30, 31, 33, 34, 35, 36, 37, 38, 39, 51, 52, 53, 56, 57, 58, 59), at least one door component (30, 31, 33, 34, 35, 36, 37, 38, 39, 51, 52, 53, 56, 57, 58, 59) being designed as a controller (30), and the method (200) has the following steps: a. storing an electronic configuration (82) of the door system (60, 61, 62) in the controller (30) and/or a mobile terminal (50), and b. carrying out at least one start-up step using the electronic configuration (82).