baber/WOPTO huggingface dataset:
Patent EC-SP109966-A (EC)
Title: Derivados de 6-fenil-1h-imidazo-[4,5-c] piridina-4-carbonitrilo como inhibidores de catepsina
Inventor: CAI JIAQIANG
IPC: A61K31/437
Filed: 2010-02-12
Abstract: La presente invención se refiere a derivados de 6-fenil-1H-imidazol[4,5-c]piridina-4-carbonitrilo teniendo la Formula general (I), a composiciones farmacéuticas que los comprenden, así como también al uso de estos derivados para la preparación de un medicamento para el tratamiento de enfermedades relacionadas con catepsina S, tales como arterioesclerosis, obesidad, desordenes inflamatorios e inmunes, tales como artritis reumática, psoriais, cancer y dolor crónico, tal como el dolor neuropático.
Patent EC-SP972065-A (EC)
Title: Benzotiofenos, formulaciones que los contienen y metodos
Inventor: ARBUTHNOT GORDON NELSON
IPC: C07D407/00
Filed: 1997-03-25
Abstract: La invención proporciona un compuesto de la fórmula I: (gráfico), y sales farmacéuticamente aceptables y solvatos de los mismos, caracterizados en que el compuesto está en forma particulada, teniendo dichas partículas un tamaño promedio de partícula de menos de aproximadamente 25 micras.
Patent EC-SP982767-A (EC)
Title: Derivados de 1,3,8- triazaspiro [4,5] decan- 4-ona
Inventor: ROEVER STEPHAN
IPC: C07D471/02
Filed: 1998-12-03
Abstract: La presente invención se refiere a compuestos de la fórmula general (gráfico), en la que 10 R1 es hidrógeno, alquilo inferior, halógeno, alcoxi inferior, trifluorometilo, alquil-inferior-fenilo o (C5-7)-cicloalquilo; R2 es hidrógeno, alquilo inferior, fenilo o alquil-inferior-fenilo; 15 R3 es hidrógeno, alquilo inferior, bencilo, alquil-inferior-fenilo, alquil-inferior-difenilo, triazinilo, cianometilo, alquil-inferior-piperidinilo, alquil-inferior-naftilo, (C5-7)-cicloalquilo, alquil-inferior-(C5-7)-cicloalquilo, alquil-inferior-piridinilo, alquil- 20 inferior-morfolinilo, alquil-inferior-dioxolanilo, alquil-inferior-oxazolilo o alquil-inferior-2-oxo-oxazolidinilo, y en el que los sistemas de anillos pueden estar sustituidos adicionalmente con alquilo inferior, alcoxi inferior, trifluorometilo o fenilo o 25 -(CH2)nC(O)-alquilo inferior, -(CH2)3C(O)NH, -(CH2)nC(O)N-(alquilo inferior); (CH2)3OH o -(CH2)nC(O) NHCH; CH; R4 es hidrógeno, alquilo inferior o nitrilo; A es un sistema deanillo, que consiste en: (a) (C,-;:) -cicloalquilo, que puede encontrarse además de R4 opcionalmente sustituido con alquilo inferior, trifluorometilo, fenilo, (C5-7)-cicloalquilo, espiro-undecan-alquilo o por 2-norbornilo, o es uno de los grupos siguientes: (gráficos), dodecahidroacenaftilen-1-ilo (e), biciclo [6.2.0]-dec-9-ilo (f) y biciclononan-9-ilo (g); y donde R5 y R6 son hidrógeno, alquilo inferior, o tomados juntos y con los átomos de carbono a los que están unidos forman un anillo fenilo; R7 es hidrógeno o alquilo inferior; la linea punteada representa un enlace opcional y n es de 1 a 4; y a sales de adición de ácido de los mismos farmacéuticamente aceptables. Los compuestos de la presente invención son agonistas y/o antagonistas del receptor de orfanina FQ (OFQ). En consecuencia serán útiles en el tratamiento de déficits de atención y memoria, transtornos psiquiátricos, neurológicos y psicoloógicos, especialmente pero no limitados a mejoria de los sintomas de trstornos deansiedad y estrés, depresión, trauma, pérdida de memoria debida a enfermedad de Alzheimer u otras demencias, epilepsia y convulsiones, estados de dolor agudo y/o crónico, sintomas de abstinencia de drogas adictivas, control del equilibrio hídrico, excresiónde Na¿, transtornosde la presión arterial y transtornos metabólicos tales como obesidad.
Patent FI-20001352-A (FI)
Inventor: KATAIKKO MIKA
IPC: H04Q/
Filed: 2000-06-06
Abstract: The invention relates to service provision in a communications network. The users of the network can access the services by sending service requests in natural language. The natural language interpretation is separated from the service implementation and execution by utilizing an intermediate layer which first generates a generic format service description out of the user input and then parses this description into information indicating the service calls to be made and the parameters relating to the said calls. This information is returned to a service logic which then implements the service in a manner known as such by making the said service calls.
Patent FI-20002890-A (FI)
Inventor: SUUMAEKI JAN
IPC: H04L12/56
Filed: 2000-12-29
Abstract: A method of configuring a compression method for a terminal in a mobile system. The mobile system comprises a terminal for which characteristics parameters are specified comprising at least the compression methods supported by the terminal, and a radio network, in which a functional entity is configured for specifying a compression method to a radio bearer. The use of a compression method on the radio bearers of the terminal is specified on the basis of the characteristics parameters transmitted by the terminal. The user of the terminal updates the parameters specifying the compression methods of the terminal, the characteristics parameters of the terminal being modified in the terminal in accordance with this update, and the modified characteristics parameters are transmitted to a function comprised by the radio network. The modified characteristics parameters are used to configure the use of a compression method for each simultaneous radio bearer of the terminal. <IMAGE>
Patent FR-1177664-A (FR)
IPC: D01D5/22
Filed: 1957-07-01
Granted: 1959-04-28
Abstract: Crimped regenerated cellulose fibre is made from viscose by submitting freshly spun filaments emerging from a conventional spinning bath to a stretch equal approximately to one third of the total stretch to be imparted, while the filaments still substantially consist of cellulose xanthate and while they are still in the plastic state, conducting the partly stretched filaments through an acid bath for their further though not yet complete transformation into cellulose hydrate, subjecting them either in, or outside, this bath to a second stretching which corresponds to the difference between the initial stretch and the total stretch, and then, after substantially completely transforming the filaments into staple lengths, immersing the staple lenths in a hot water or alkaline bath, and finally submitting them to conventional after-treatment. Preferably the partially stretched filaments are 70-95% converted to cellulose hydrate prior to the second stretch, which may be carried out in an aqueous sulphuric acid bath.  Preferably, also, the viscose has a ratio of alkali to a -cellulose of below 0.9, e.g. 0.8-0.85. The total stretch of the fibre may correspond to 60-65% of its original length.  An example is given.  Specification 499,671 is referred to.
Patent GB-1016506-A (GB)
IPC: H05K7/12
Abstract: 1,016,506. Bolts; washers. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. Oct. 17, 1963 [Oct. 20, 1962; Dec. 12, 1962], No. 41071/63. Heading F2H. [Also in Division H1] A mounting device for an electrical component comprises a bolt with a hollowed head forming a housing for the component, the wall being slotted to form a split clamp, and a threaded shank 5 extending from the head with means for applying pressure to the edge of the head base (when the shank is inserted in an aperture of a mounting plate 17) to close the split clamp about the component. The base has a groove 15 so that when the bolt is screwed into a threaded hole or secured by a nut 21 the housing walls are levered inwards. The head base may be flat and a washer with a hole larger than the shank diameter may be used with it to produce the leverage. The washer may have at its edge an upstanding flange or lugs, Figs. 4, 5 (not shown).
Patent GB-1023059-A (GB)
IPC: D05B33/00
Abstract: 1,023,059. Reciprocating conveyers. DURKOPPWERKE A.G. Dec. 2, 1964 [July 4, 1964], No. 48945/64. Heading B8A. [Also in Division D1] A conveyer comprises a first compressed air motor adapted to impart an advancing stroke to means engaged with a workpiece, a first rod coupled to the piston rod of said motor, a second rod parallel to the first rod and coupled thereto by levers pivoted on the first rod, and a second compressed air motor the piston rod of which is coupled to the second rod via a cranked lever to effect disengagement of said means from the workpiece at the end of the advancing stroke. As shown, a single-stroke compressed air motor 3, the piston of which is spring-biased inwardly, is clampable in an axially-adjusted position in a block 2 fixed to a base 1. A plate 24, fixed to motor 3, slidably engages base 1 and carries a micro-switch 25 the plunger of which extends through plate 24. The piston rod of said motor is connected by an arm 8 to a rod 5 which is slidable in fixed blocks 2 and 6, and which fixedly carries an arm 13. Arms 10 and 10<SP>1</SP>, pivoted on rod 5, are interconnected by a rod 9. A second single-stroke compressed air motor 4, the piston of which is spring- biased inwardly, is fixed in block 2, and its piston rod 15 is connected by a link 17 to one arm 19 of a bell-crank lever pivoted on block 6. The other arm 19<SP>1</SP> carries a sleeve 20 in which is pivoted a block 21 slidably receiving rod 9. An arm 34 fixed to rod 9 pivotally carries a boss 36 which slidably receives the cranked end of a rod 37 pivoted in blocks 38 fixed to the worksupporting plate 33 of a sewing machine. Arms 40, fixed to rod 37, carry feet 43 which are normally biased by the spring means in motor 4 to engage work 45 on plate 33. Air supplied to motor 3 serves to feed the work until arm 13 engages the plunger of micro-switch 25, whereby air is supplied to motor 4 for lifting feet 43 and air is exhausted from motor 3 for permitting the spring means associated therewith to return feet 43 to their initial position. The length of the feeding stroke is varied by adjusting the axial position of motor 3 in block 2. It is stated that the conveyer is usable wherever it is important to move workpieces in one direction by a constant but adjustable length, e.g. from one work place to the next or from one treatment machine to another.
Patent GB-1050494-A (GB)
IPC: A63J19/00
Abstract: 1,050,494. Puppets. E. M. GRANGER. Nov. 4, 1965 [Nov. 4, 1964], No. 45055/64. Heading A65. A puppet is controlled from below by means of nylon cords which pass through rods 2, 4 from hand grip plates 1 on which control levers are placed. One cord acts on a pulley 20 to produce twisting movement of the arm of the puppet, while pulling on one or other of two cords produces bending at the wrist in one or other direction, respectively. Pulling equally on both cords merely produces bending at the elbow.
Patent GB-1051193-A (GB)
IPC: C08F36/04
Abstract: 1,051,193. Vulcanizing elastomers. ESSO RESEARCH & ENGINEERING CO. March 24, 1964 [April 19, 1963], No. 12441/64. Heading C3P. A conjugated aliphatic diolefin polymer or copolymer of molecular weight within the range 1000 to 15,000 is heated to 110‹ to 175‹ C., has incorporated therein while stirring constantly and allowing the temperature to rise, sulphur vulcanization accelerators, is then activated to thicken the mass, further amounts of vulcanization accelerators added and the vulcanization completed by further heating. The conventional adjuvants such as fillers, dyestuffs, pigments, fibres and stabilizers may be added.
Patent GB-1051822-A (GB)
IPC: E06B3/48
Abstract: 1,051,822. Extruding composite strips. MILANI RESINE S.p.A. Nov. 26, 1964 [Dec. 2, 1963], No. 48041/64. Heading B5A. [Also in Divisions E1 and E2] The panels of a collapsible folding leaf of a door or partition &c. are formed of side-by-side joined flexible strip and rigid strip of preferably the same plastics material plasticized to different degrees, by extruding the materials from respective sources to a composite extruder head comprising an inlet head 27 for what will be the rigid plastics material and having an orifice of the required cross-section 28, a part 29 made in two pieces 30, 31, each of which has extension to form a baffle 32 which separates an orifice 34 from the orifice 33. The orifice 34 feeds from the part 29, that material which will be the flexible portion of the panel and the orifice 33 is a continuation of the orifice 28. Orifices 34, 33 feed to corresponding orifices in part 35 which has a semi-circular orifice 37 for the flexible material and two flat portions 36, 38 for the rigid material, a hole for the core 40 surrounded by holes 39 to produce a tubular rigid portion and a hole 41. The materials proceed to part 42, 43 which is in two pieces having cavities to sandwich between them pieces 46 and 53 forming a cavity 48, 49, 50, cavities 48, 50 merging into cavity 49, to join the materials from cavities 36, 38 and that from cavity 37, the cavity 50 terminating in a hole 51 from which issues the tubular member which is integral with the rigid member and formed by the core 40. Cavity 48 terminates in a hole 55 which accommodates the piece 53 to form a forked portion in the end of the rigid member.
Patent GB-1225515-A (GB)
IPC: B29C48/395
Filed: 1968-04-17
Abstract: 1,225,515. Working plastic materials. H. LEU AND H. KOCHER. 17 April, 1968 [17 April, 1967], No. 18175/68. Heading B1C. Apparatus for working plastic materials comprises a barrel 1 having a rotor 2 comprising a divergent portion 5 to induce turbulence, a cylindrical portion 6, a further divergent portion 7 to stabilise flow, a further cylindrical portion 8 and a convergent portion 10. The barrel may be surrounded by annular chambers 18-22 through which a heat transfer medium may be circulated, and it may be lined with a quartz-glass sleeve 26 and provided with a roughened surface 29 in the zones shown. The rotor may be provided with a screw 4, or truncated cone, to feed material through the barrel. Turbulence may be induced by providing diverging portion 5 with a profile having a change of curvature at one point, Fig. 3 (not shown), and stability of flow may be introduced by providing diverging portion 7 with a profile of exponenential shape, Fig. 4 (not shown). The convergent portion 10 of the rotor may be provided with an axial groove, Figs. 5, 6 (not shown). A high frequency generator 25 may be connected to the barrel and rotor by contacts 23, 24.
Patent GB-1230271-A (GB)
IPC: A01G27/06
Filed: 1969-11-25
Abstract: 1,230,271. Watering plants. N. CALTAGIRONE. 25 Nov., 1969 [28 Nov., 1968], No. 57575/69. Heading A1E. A device for controlled watering of potted plants comprises a container 1 divided into two compartments by a partition 2. The bottom of the container is covered with capillary material 11. Compartment 3 of the container contains either soil or a plant pot 13 having capillary element 12 connecting the soil to capillary material 11. Compartment 4 of the container holds a liquid filled cartridge 5 having bung 6. Bung 6 has capillary element 9 connecting it to material 11 and a capillary slot 10 connecting with the atmosphere. The size of slot 10 controls the degree of wetness in the soil of plant pot 13.
Patent GB-1230405-A (GB)
IPC: B31B41/00
Filed: 1968-04-03
Abstract: 1,230,405. Wrapping enclosure containing envelopes; feeding sheets. WIGGINS TEAPE (IRELAND) Ltd. 3 April, 1968 [3 April, 1967], No. 16074/68. Headings B8C and B8R. In a method of forming an enclosure containing envelope an enclosure 7 is temporarily located on an envelope blank 1 by a strip of adhesive 6 which is rendered ineffective upon application thereto of heat and two side flaps 2, 3, Fig. 4, are folded about the enclosure 7 and adhesive 8 is applied to their outer free edges, a flap 4 being folded over (Fig. 5, not shown) and sealed to the flaps 2, 3 whereupon a flap 5 is folded and sealed to the remaining exposed adhesive and the adhesive strip 6 is rendered ineffective by heating the envelope. The envelope is opened by gripping and pulling back a flap tip 5a which overlies a flap tip 4a and consequently receives no adhesive. An apparatus for folding is not described but it is stated that a conventional envelope forming and/or printing machine may be modified. A rotatable element having V-shaped gluing members for applying the adhesive may be provided. A lowermost enclosure 7 is fed from a stack 12 held between adjustable guides 15 on a plate 11. As a suction member 16 rises, an arm 17 pivots upwardly about shaft 31 to temporarily release the lowermost blank which is engaged by the suction head 16a and pulled downwardly, the arm 17 returning to engage beneath the remainder of the stack. The enclosure is pulled between cutaway parts of continuously rotating wheels 44, 45 which have lobes 57, 58 with suction holes 67, 68 to hold the sheet to the wheel rims and transport it away. The envelope blank feed means may be similar to that for the enclosure.
Patent GB-1230870-A (GB)
IPC: E01H1/04
Filed: 1968-10-21
Abstract: 1,230,870. Sweeping-up leaves. ERNEST A. WEBB Ltd. 21 Oct., 1969 [21 Oct., 1968], No. 49764/68. Heading A1E. [Also in Divisions A4 and E1] A rotary-brush road or ground sweeping attachment 10, Fig. 1, mounted on the lift arms 25 of a tractor 26 comprises a receptacle 11 having a discharge door 21, and a brush cylinder 12 geared to a hydraulic motor 17, Fig. 3, coupled to the tractor hydraulic system. The brush 12 consists of sections 13 on two hollow square shafts 14 carried by a chain driven shaft 16, the shaft bearings 36 and the motor-support channel 39 being adjustably positioned by slotted plates 31, 32 to accommodate brush wear. The tractor lift arms 25 pass through the rear wall of the receptacle 11 and are secured internally by pins 24 and externally by brackets 27. The receptacle shown has a hinged top cover 19, a bottom, hinged rear door 21 and a front spray tube 28. In a modification, Fig. 6 (not shown), the brush cylinder can tilt about a rod (45) to accommodate road camber, the receptacle (11) having adjustable brush side covers (48), a castor wheel (47) and a bottom door (21). In a further modification, Figs. 4, 5 (not shown) the receptacle (11) can swing about a vertical axis, by adjusting bolts (43), so that the brush cylinder is no longer aligned with the tractor wheels and can be reversedriven to heap rubbish to one side of the advancing tractor, instead of collecting it.
Patent GB-1232646-A (GB)
IPC: A23G1/20
Filed: 1968-06-28
Abstract: 1,232,646. Moulding plastic substances &c. S. WESTIN. 28 June, 1968, No. 31048. Heading B5A. [Also in Division B8] A method of moulding double sided confectionery articles in a mould of plastics sheet material having recesses symmetrically located about at least one longitudinal or lateral fold line, e.g. perforations, comprises filling up the recesses on one side of the fold line and allowing partial setting to provide one half of the article and then filling the other recesses whereupon the first filled recesses are folded through 180 degrees to rest upon the unset halves so effecting bonding of the halves. The sheet may be welded at its edges after folding and the articles cut out of the sheet in suitable bars. If an uneven number of fold lines is used the adjacent fold lines are folded in opposing directions. Two longitudinal fold lines may be arranged so that the distance between each of them and the respective longitudinal sheet edge is one quarter of the total sheet width, the recesses between them and the edges matching those between the fold lines. The moulds may be advanced during feeding by a gear wheel engaging the perforations.
Patent GB-1233848-A (GB)
IPC: B08B15/00
Filed: 1969-05-13
Abstract: 1,233,848. Removing noxious fumes generated in industrial processes. E. A. LINDKVIST. 13 May, 1969 [13 May, 1968], No. 24448/69. Heading F4X. An exhaust system for removal of gaseous contaminants generated in workshops by machines movable in such premises comprises an overhead rail 2 having at least one exhaust duct 1 fixedly secured either thereto or to a ceiling by brackets 8 along its length with a slot or holes on its downwardly facing side which is or are sealed on either side by resilient strips 11. The slot or holes are adapted to be placed in operative connection with ducts or hoses 6 movable to the source of the contaminants by tapping units 5 including a ploughshaped nozzle portion and connecting portion 19 which units are supported by trolleys having yokes 17 and wheels 9. The units are adapted to run along the track and the nozzle portions move the sealing strips apart when establishing communication between the fixed and movable ducts.
Patent GB-1234033-A (GB)
IPC: B62K3/10
Filed: 1967-08-31
Abstract: 1,234,033. Bicycles. HALFORDS Ltd. 27 Aug., 1968 [31 Aug., 1967], No. 39778/67. Heading B7E. A bicycle comprises a frame including a saddle support tube 13 and two spaced-apart side-byside, one-piece tubular rear wheel support members 16 extending rearwardly from the tube 13 and having horizontal sides 28, the upper end of each tube being flattened and arcuately shaped to fit the tube 13 to which it is welded or brazed, and the lower end 24 of each tube 16 being mounted inside a socket 22 fixed to tube 13. The sides 28 may be joined by a brace 37 providing support for a saddle bag, and the lower sides joined by a brace 34. A flat bracket 43 is welded or brazed to the outer side 30 of each tube 16 for supporting rear wheel 41.
Patent GB-1238134-A (GB)
IPC: A61K31/135
Filed: 1969-11-14
Abstract: 1,238,134. 3-N-(2-hydroxy-3-phenoxypropyl)- amino - 1 - phenyl - 1 - propanone and salts. KALI-CHEMIE A.G. 14 Nov., 1969 [6 Dec., 1968], No. 65959/69. Heading C2C. The novel compound 3-N-(2-hydroxy-3-phenoxypropyl)-amino-1-phenyl-1-propanone and salts thereof are prepared by reacting 2-hydroxy- 3 - phenoxy - propylamine with either HCl, acetophenone, and formaldehyde or phenyl vinyl ketone prepared by action of potassium acetate on #-chloropropiophenone optionally followed by interconversion of base and/or salt. Pharmaceutical compositions in conventional form for oral administration and having a sedative and hypotensive activity comprises the above novel compound or salt thereof and a pharmaceutically acceptable solid diluent or carrier.
Patent GB-1238905-A (GB)
IPC: B07B1/30
Filed: 1968-08-28
Abstract: 1,238,905. Vibratory screening apparatus. F. K. MOGENSEN and L. C. MOGENSEN. 28 Aug., 1968 [30 Aug., 1967], No. 41174/68. Heading B2H. A classifier for classifying material passed through it in a freely dispersed state comprises a series of screens each having openings preferably at least 1.5 times as large as the particles supplied to it and arranged one above the other and in a sloping position wherein at least one of the screens is adjustably mounted with regard to its inclination relative to the horizontal. As shown the screens are mounted in a frame member 6 which is suspended by springs 8 and is connected to a vibrator 9 which vibrates the screens so that the particles are caused to advance down the inclined surfaces.
Patent GB-1256961-A (GB)
IPC: B65D71/00
Filed: 1969-02-13
Abstract: 1,256,961. Carrying pack. ETABS DEVOISSELLE & CIE. 13 Feb., 1969 [27 Feb., 1968; 21 May, 1968], No. 7787/69. Heading B8C. A pack for carrying containers e.g. bottles, is formed from a blank glued or welded into a tube which may be flat or unfolded, the tube having a top face, a base having at least one aperture, lateral faces connecting the top face and base and a retaining device at each end connected solely to the lateral faces, whereby the pack can be unfolded by passing a pin through the aperture to push the upper face away. As shown in Fig. 1, the pack comprises a base 2 containing the join of the two ends of the blank by securing tongues (1, Fig. 2, not shown), a top 4, sides 3 divided into inclined sections 3a, 3, 3b by folds 5, 6 and retaining flaps 10 at each end connected solely to sides 3 by triangular flaps 11. Bottom section 2 also contains apertures (7, Fig. 2) for passage of the pins. The fold 5 is so positioned that the width of bottom 2 and adjacent side sections 3, 3b is equal to that of top 4 and adjacent side sections 3a. The folded tubes are taken from a magazine (M, Fig. 3, not shown) by suction device (V) or by hooks, pins (D) passing through apertures 7 pushing top 4 to open the pack partially before it is passed into shaping compartment (A) to complete erection.