baber/WOPTO huggingface dataset:
Patent DE-69112108-T2 (DE)
Inventor: YAMANAKA AKIHITO
IPC: A61K9/70
Filed: 1991-04-13
Granted: 1996-01-11
Abstract: A medical adhesive comprising a plaster layer containing the following ingredients, characterized in that the ingredient 2/ &cir& is incorporated in a larger amount than the ingredient 5/ &cir& and in an amount not less than 25% by weight relative to the total amount of the ingredients 1/ &cir&  SIMILAR 5/ &cir& , and the plaster layer is a W/O type :     1/ &cir&  a medicinal ingredient, 2/ &cir&  a hydrophobic polymer having a glass transition temperature (Tg) of -65 DEG C to 35 DEG C,   3/ &cir&  a percutaneous absorption-promoting agent,   4/ &cir&  water, and 5/ &cir&  a hydrophilic polymer which is soluble or capable of swelling in water; and a medical adhesive which comprises a porous base layer in the plaster layer or in contact with the plaster layer, which enable stable release of the medicinal ingredient, the percutaneous absorption-promoting agents and so on and sustaining of the pharmacological effects over a long period.
Patent DE-69114786-T2 (DE)
Inventor: VAN LINTEL HARALD
IPC: H01L21/308
Filed: 1991-03-07
Granted: 1996-05-23
Abstract: PCT No. PCT/EP91/00426 Sec. 371 Date Nov. 12, 1991 Sec. 102(e) Date Nov. 12, 1991 PCT Filed Mar. 7, 1991 PCT Pub. No. WO91/14181 PCT Pub. Date Sep. 19, 1991.Flat-bottomed cavities are formed in a substrate (2) by a method comprising two etching steps: a first anisotropic etching through a mask (4) leaving exposed bands (6,8) of the substrate (2) and a second anisotropic etching through a mask leaving exposed all of the zones (Z1, Z2) to be etched. The first etching provides grooves in V form (10,12), the depth of X1, X2) which depends on the width of the bands, while the second etching increased the depth of the cavities by the same amount y, in eliminating the bands located between the grooves. Advantage: flat cavities of different depths may be obtained simultaneously.
Patent DE-69114955-T2 (DE)
Inventor: KAMASHITA TOMOKO
IPC: C07C229/00
Filed: 1991-08-27
Granted: 1996-07-25
Abstract: The present invention discloses a method for extracting an amino acid ester, which method comprises adding a water-insoluble organic solvent to a hydrous solution containing a mineral acid salt of an amino acid ester, then adding a base thereto to liberate the amino acid ester, and transferring the amino acid ester into the organic layer, which method is characterized in that the extraction is carried out by keeping the pH of the aqueous layer at 7-8.
Patent DE-69117814-T2 (DE)
Inventor: KERIHUEL JEAN-BERNARD
IPC: H04L9/32
Filed: 1991-05-27
Granted: 1996-07-25
Abstract: It consists in: - storing and updating, in the databases of operating points (14, 15, 16), words identifying each subscription and the corresponding telephone, and a secret key; - transmitting from the telephone (T1) of the requester, to a network service operating point (14), words identifying the subscription of the requester and his telephone; - determining in the telephone (T1) of the requester a first signature dependent on a random number and on the secret key; - transmitting it to the said network service operating point (14) via the user-to-user signalling channel (D); - determining in the said network service operating point (14) a second signature depending on the same random number and on the secret key; - verifying in the said network service operating point (14) that: the first and the second signatures are identical; that the word identifying the subscription corresponds to a valid subscription; that the word identifying the subscription corresponds to the word identifying the telephone of the requester. Application to cordless telephone networks. <IMAGE>
Patent DE-69118566-T2 (DE)
Inventor: LEVIEN RAPHAEL L
IPC: H04N1/46
Filed: 1991-02-06
Granted: 1996-10-24
Abstract: Tone values of a photographic image are stored in a frame store (20) and retrieved from the frame store to produce a corresponding video display. A mouse (17) or trackball is used to locate a point on display and a gamma correction curve look up table (22R,22G,22B) is used to interactively show the effect of color correction. Adjustment can be made via lighter and darker switches (14,15) on the mouse or trackball. These switches subtract or add a bump function to the gamma correction curve in the selected color density plane. The bump function is displaced by the measured tone value in order to achieve more flexible control over the color correction. <IMAGE>   <IMAGE>
Patent DE-69119166-T2 (DE)
Inventor: SCHIRMER HENRY G
IPC: C08J5/18
Filed: 1991-08-13
Granted: 1996-11-21
Abstract: A multilayer film comprises a first layer comprising propylene homopolymer or copolymer and at least one additional sealable layer; or a core layer comprising very low density polyethylene, two outer sealable layers and intermediate adhesive layers.
Patent DE-69119690-T2 (DE)
Inventor: WATANABE ATSUO
IPC: D21F3/08
Filed: 1991-10-07
Granted: 1996-10-02
Abstract: A paper machine press roll (1) comprising a metal core (2), a ground layer (4) formed over the outer periphery of the core (2) and made of a metal material having a small coefficient of expansion, and a mixture layer (3) formed over the outer periphery of the ground layer (4) and comprising a ceramic and a water retentivity imparting particulate substance such as mica. At least in a surface layer portion of the mixture layer (3), an organic high polymer such as synthetic resin or wax is filled in the interstices between particles of the ceramic and particles of the water retentivity imparting substance. <IMAGE>
Patent DE-69122259-T2 (DE)
Inventor: KUN ERNEST
IPC: C07D311/14
Filed: 1991-10-16
Granted: 1997-02-06
Abstract: Unsubstituted or substituted 5-iodo-6-amino-1,2-benzopyrones and their metabolites are potent, selective and non-toxic inhibitors and supressants of cancer growth and viral infections in a mammalian host. The compounds are particularly useful for treatment and supression of tumors and viruses associated with AIDS, herpetic episodes and cytomegaloviral infections. The methods of treatment of tumorigenic and viral diseases by 5-iodo-6-amino-1,2-benzopryrones and/or its metabolites are described.
Patent DE-69130818-T2 (DE)
Inventor: SUZUKI FUJIO
IPC: C12N15/09
Filed: 1991-08-23
Granted: 1999-06-17
Abstract: A novel chondromodulin-I protein having a molecular weight of about 26,000 dalton on SDS-PAGE and capable of stimulating the growth of chondrocytes with or without FGF and promoting the differential potency of said cells, a DNA encoding said protein, expression vector containing said DNA, a transformant capable of producing recombinant chondromodulin-I protein, a process for producing chondromodulin-I protein by culturing said transformant and a pharmaceutical composition containing chondromodulin-I protein as an active ingredient.
Patent DE-69206721-T2 (DE)
Inventor: BRION FRANCIS
IPC: C07J21/00
Filed: 1992-09-03
Granted: 1996-05-23
Abstract: The subject of the invention is a process for the preparation of the hydrocortisone (I): 
<IMAGE>
 from the halohydrin (II): 
<IMAGE>
 where X is a halogen, as well as intermediate compounds.
Patent DE-69206987-T2 (DE)
Inventor: MA THOMAS
IPC: F01N3/22
Filed: 1992-06-10
Granted: 1996-05-23
Abstract: PCT No. PCT/GB92/01035 Sec. 371 Date Dec. 10, 1993 Sec. 102(e) Date Dec. 10, 1993 PCT Filed Jun. 10, 1991 PCT Pub. No. WO92/22734 PCT Pub. Date Dec. 23, 1992.A method is described for reducing the total emissions during cold starts from an engine burning a hydrocarbon fuel and having an afterburner arranged upstream of a catalytic converter. The method comprises the steps of: (i) adding an excess of fuel to the engine combustible charge and adding air to the engine exhaust gases immediately after the engine has first fired to assure the presence in the exhaust/air mixture of sufficient concentrations of hydrogen and oxygen to permit the resulting exhaust/air mixture to be ignitable and to burn with a steady flame in the afterburner while the latter is at a temperature close to the ambient temperature, and (ii) igniting the exhaust/air mixture in the afterburner immediately after the engine has first fired. In the preferred embodiment of the invention, the excess fuel and/or the additional air are regulated after ignition has occurred in the afterburner to maintain a steady flame in the afterburner until at least part of the matrix of the catalytic converter has reached its light off temperature.
Patent DE-69211936-T2 (DE)
Inventor: SOKUKAWA MASAKI
IPC: C07C69/716
Filed: 1992-09-30
Granted: 1996-11-07
Abstract: There is disclosed a process for producing lower alkyl 2-keto-L-gulonate which comprises reacting 2-keto-L-gulonic acid with a lower alcohol in the presence of an acid, and simultaneously distilling off the resulting water together with the lower alcohol while continuously introducing a lower alcohol. By using the lower alkyl 2-keto-L-gulonate thus produced, L-ascorbate can be prepared in high purity and high yield.
Patent DE-69223793-T2 (DE)
Inventor: WESTON TERENCE EDWARD
IPC: A61M5/30
Filed: 1992-08-21
Granted: 1998-04-23
Abstract: PCT No. PCT/GB92/01539 Sec. 371 Date Aug. 4, 1994 Sec. 102(e) Date Aug. 4, 1994 PCT Filed Aug. 21, 1992 PCT Pub. No. WO93/03779 PCT Pub. Date Mar. 4, 1993.A needleless injector having a liquid metering chamber with an outlet orifice, a piston slidable within the metering chamber, and a rod arranged to strike one end of the piston to force liquid through the outlet orifice. A cam follower is mounted at one end of the rod to ride on a cam that retracts the rod away from the piston. The injector is in two parts which are biassed away from each other. The front part of the injector carries the outlet orifice and the rear part carries the cam. Actuation occurs when the two parts of the injector are sufficiently urged towards each other by the user to actuate the cam to release the rod and thereby strike the piston and force liquid through the outlet orifice.
Patent DE-69227790-T2 (DE)
Inventor: PANZONE GIANBATTISTA
IPC: C07D513/18
Filed: 1992-01-13
Granted: 1999-06-10
Abstract: The present invention relates to a new one-pot process for preparing 2'-(diethylamino)rifamycin P and its 25-desacetyl derivative of formula (I) which consists in cyclizing 3-bromorifamycin S or its 25-desacetyl derivative of formula (II), dissolved in dimethylformamide, with 1,1-diethylthiourea and reducing, without isolation, the obtained 1,2-quinonimine intermediate of formula (III) with a mild reducing agent. <CHEM> a
Patent DE-69229688-T2 (DE)
Inventor: BALDWIN JOHN J
IPC: A61K31/445
Filed: 1992-04-14
Granted: 2000-02-24
Abstract: Combinations of a  beta -adrenergic antagonist and a topical carbonic anhydrase inhibitor are particularly useful in the treatment of ocular hypertension, especially in patients insufficiently responsive to treatment with  beta -adrenergic antagonists. <IMAGE>
Patent DE-69233597-T2 (DE)
Inventor: ROCKWOOD CHARLES A
IPC: A61F2/00
Filed: 1992-11-18
Granted: 2006-08-10
Abstract: An implant apparatus for replacing a portion of a humerus comprises a body (30a), a head member (44a) sized to replace a head portion of the humerus, and means for eccentric attachment of the head member (44a) to the body (30a) to allow adjustable superior/inferior and anterior/posterior positioning of the head member (44a) relative to the body (30a).  <IMAGE>
Patent DE-69302695-T2 (DE)
Inventor: ZITO RALPH
IPC: H01M8/20
Filed: 1993-10-13
Granted: 1996-09-26
Abstract: An electrochemical apparatus for power delivery employs an array of electrochemical cells which comprises an end +ve electrode and an end -ve electrode separated by one or more bipolar mid-electrodes each with a +ve side and a -ve side, the +ve side of each bipolar electrode comprising an electrically conductive substrate with a porous conductive surface. A bubbly dispersion of air/oxygen in an electrolyte is contacted with the +ve sides of the bipolar electrodes. The electrochemical apparatus of the invention may be used with an oxygen-sulfur couple with these reagents being provided for example as sodium salts in aqueous solutions, the overall reaction being:4H2O+4S2-+2O2->8OH-+4S,The process is preferably carried out in an array of cells (20), comprising a plurality of bipolar electrodes 13, each having a +ve side 12A and a -ve side 14A spaced from one another by membranes 16 which divide the cell into +ve and -ve chambers (22C and 24C) for posilyte and anolyte solutions (22, 24) which are circulated through the chambers.
Patent DE-69304237-T2 (DE)
Inventor: RUPPEL REMY
IPC: D21H27/40
Filed: 1993-03-22
Granted: 1997-01-16
Abstract: The invention relates to multi-ply embossed papers, more particularly multi-ply papers containing an embossed sheet (1) of paper exhibiting protuberances of different depths produced during its embossing, characterised in that deeper protuberances (11) called large protuberances alternate with protuberances so that the small protuberances (12) can be placed in a point-to-point position with the protuberances (22) of a second sheet of embossed paper (2) and in that the large protuberances (11) fit between the protuberances (22) of the second sheet (2). The invention also relates to a process and a device for the production of these multi-ply embossed papers. <IMAGE>
Patent DE-69306670-T2 (DE)
Inventor: BOELSTERLI JOHANN JAKOB
IPC: A61K38/00
Filed: 1993-02-22
Granted: 1997-07-03
Abstract: Cyclosporins wherein the residue at the 1-position has the formula I   <CHEM> in which -x-y- is -CH=CH-(trans) or -CH2-CH2-, X is 0 or S and R is hydrogen, optionally halo or hydroxy substituted-C1-3-alkyl, -alkoxy or -alkylthio, or amino or mono- or di-(C1-2alkyl)-amino, useful as pharmaceuticals, preferentially for topical administration in particular for asthma therapy.
Patent DE-69307709-T2 (DE)
Inventor: WAINWRIGHT ROBIN
IPC: C09D5/18
Filed: 1993-07-16
Granted: 1997-09-04
Abstract: PCT No. PCT/GB93/01511 Sec. 371 Date Mar. 10, 1995 Sec. 102(e) Date Mar. 10, 1995 PCT Filed Jul. 16, 1993 PCT Pub. No. WO94/02545 PCT Pub. Date Feb. 3, 1994.An intumescent composition comprises saline soluble inorganic silicate fibrous material containing CaO, MgO and no more than 4% by weight of Al2O3, such as calcium magnesium silicate. The fibres may be vitreous, with an average length of 10 to 500 microns, and may form 5 to 30 weight percent of the composition. The composition may be incorporated in a coating composition, e.g. for wet coating (paint) or powder coating, or a mastic or putty, or a composition containing a polymer. Enhanced fire protection can be provided, and the coating compositions may be applied as a single thick coating rather than by building up thin layers.
Patent DE-69309563-T2 (DE)
Inventor: FRANCOIS PHILIPPE
IPC: C08F10/00
Filed: 1993-07-09
Granted: 1997-11-13
Abstract: Catalytic solid based on complexed titanium trichloride which can be used for the stereospecific polymerisation of alpha-olefins obtained according to a process comprising at least the following stages:   (a) reduction of titanium tetrachloride (TiCl4) by an organoaluminium compound to obtain a reduced solid based on titanium trichloride (TiCl3); (b) simultaneous or successive treatments of the reduced TiCl3-based solid with an electron-donating compound and a halogenated compound;   (c) activation by bringing into contact with an activating agent; characterised in that the reduced TiCl3-based solid resulting from Stage (a) additionally comprises from approximately 1 to approximately 1000 % by weight of prepolymerised ethylene with respect to the amount of TiCl3.
Patent DE-69314385-T2 (DE)
Inventor: TAHON BERNARD
IPC: F27D11/10
Filed: 1993-06-15
Granted: 1998-04-16
Abstract: Coupling for the rigid and stationary end-connection of graphite or carbon electrodes whose ends contain a sleeve tube with an internal threading into which is screwed a double-threaded connector or nipple pierced with holes acting as reservoirs containing a solid and electrically conductive cement, characterised in that at least one of the said reservoirs is filled with a synthetic cement consisting of a thermosetting resin, which, in the presence of a catalyst, melts at a temperature greater than 60 DEG C in order to form a liquid phase with a viscosity below 2500 centipoises between 90 DEG C and 120 DEG C and to polymerise at a temperature greater than or equal to 120 DEG C. <IMAGE>
Patent DE-69316530-T2 (DE)
Inventor: SCHEFFEE ROBERT S
IPC: B60R21/26
Filed: 1993-09-30
Granted: 1998-05-07
Abstract: A two-part igniter for inflators used to inflate inflation devices such as air bags, lift rafts, slide chutes, and the like which includes a heterogeneous mixture of an ignition material and a consolidated mass of either i) a pyrotechnic component or ii) a composite propellant. The ignition material can be in a granular form or pelletized. The pyrotechnic component or composite propellant is provided as a pellet which is in immediate contact with the ignition material. The pyrotechnic component or composite propellant lowers the auto-ignition temperature of the two-part igniter. The two-part igniter can be used in inflators which generate all inflation gases from gas-generating compositions and in inflators which include a supply of stored pressurized inflation gases.
Patent DE-69316636-T2 (DE)
Inventor: BAE YOU
IPC: A61F2/02
Filed: 1993-09-28
Granted: 1998-05-07
Abstract: An artificial pancreas system which minimizes the volume of the artificial pancreas by not encapsulating each islet is taught wherein the islets are separated and held within a polymeric matrix which is soluble in an aqueous solution below body temperature but insoluble in aqueous solutions at or above body temperature. The polymer-islet mixture is contained in a pouch having access means such as entry and exit ports. The solubility makes it possible to replace the contents of the pouch by solubilizing the matrix simply by lowering the temperature below the LCST. The pouch is constructed of a biocompatible material permeable to insulin and other substances of similar or lesser molecular weight but is impermeable to cellular and humoral components of the body immune system. The islet-polymer matrix can be functionalized to stimulate insulin secretion from the islets using insulinotropic agents such as sulfonylurea. Also, polymeric microparticles which release bioactive agents which either promote vascularization at the pouch membrane outer surface or inhibit macrophage activity can be added to the polymer matrix.
Patent DE-69320470-T2 (DE)
Inventor: WARD ROBERT
IPC: C08G18/48
Filed: 1993-04-23
Granted: 1999-04-29
Abstract: A biocompatible, hydrophilic, segmented block polyurethane copolymer which comprises 5 to 45 wt % of a hard segment and 95 to 55 wt % of a soft segment selected from a hydrophilic, hydrophobic and amphipathic oligomer is disclosed. The copolymer is capable of forming a non-porous, semi-permeable film of a tensile strength greater than 300 and up to 10,000 psi, and has an ultimate elongation greater than 300% and up to 1,500% and a water absorption such that the sum of the volume fraction of absorbed water and the hydrophilic volume fraction of the soft segment exceeds about 100% and is up to about 2,000% of the dry polymer volume. The film is permeable to cell nutrients and waste molecules of up to about 6,000 to 600,000 molecular weight and is substantially impermeable to cells and particulate matter. A non-porous, semi-permeable, biocompatible film is formed from the block copolymer of the invention in the form of a flexible sheet or a hollow fiber. Also disclosed is a method of permeating molecules of a predetermined molecular weight range while preventing the passage of larger molecular weight molecules, cells, and condensed phases of matter between two fluids comprising interposing between the two fluids the non-porous film of the invention.
Patent DE-69333627-T2 (DE)
Inventor: MAEDA HIROAKI
IPC: C07K16/10
Filed: 1993-01-14
Granted: 2005-09-22
Abstract: The invention relates to a gene fragment which codes for the variable regions of an antibody having an activity of neutralizing human immunodeficiency virus (HIV), a novel recombinant anti-HIV antibody expressed by using the above gene, and a process for preparing the same. A mouse-human chimeric antibody and a modified mouse-human antibody, having an activity of neutralizing HIV, are obtained by determining a specific nucleic acid sequence of a gene fragment which codes for the variable regions of the H and L chains of an antibody having an activity of neutralizing HIV and artificially fusing a DNA synthesized on the basis of the determined sequence with a gene which codes for human immunoglobulin. The novel anti-HIV antibody is useful for treating and preventing AIDS.
Patent DE-69333726-T2 (DE)
Inventor: KINDSVOGLE R
IPC: G01N33/50
Filed: 1993-08-30
Granted: 2006-02-23
Abstract: The present invention provides isolated DNA molecules comprising a DNA segment encoding a glucagon receptor. Also provided are DNA constructs comprising a first DNA segment encoding a glucagon receptor operably linked to additional DNA segments required for the expression of the first DNA segment, as well as host cells containing such DNA constructs. The present invention also provides a method for detecting the presence of glucagon antagonists, comprising the steps of (a) exposing a compound in the presence of a glucagon against to a recombinant glucagon receptor coupled to a response pathway under conditions and for time sufficient to allow binding of the compound to the receptor and an associated response through the pathway, and (b) detecting a reduction in the stimulation of the response pathway resulting from the binding of the compound to the glucagon receptor, relative to the stimulation of the response pathway by the glucagon agonist alone and therefrom determining the presence of a glucagon antagonist.
Patent DE-69334012-T2 (DE)
Inventor: OESTLUND AKE
IPC: C23C14/02
Filed: 1993-02-19
Granted: 2006-11-23
Abstract: A cemented carbide insert with improved toughness and resistance against plastic deformation containing WC and cubic phases of carbide and/or carbonitride in a binder phase based on Co and/or Ni with a binder phase enriched surface zone is disclosed. The binder phase content in the insert is 3.5-12 weight-%. In a zone below the binder phase enriched surface zone, the binder phase content is 0.85-1 of the binder phase content in the inner portion of the insert and the content of cubic phases is essentially constant and equal to the content in the inner portion of the insert.
Patent DE-69401732-T2 (DE)
Inventor: CHUDY ANDRZEJ M
IPC: B65B13/30
Filed: 1994-10-05
Granted: 1997-06-19
Abstract: A strapping tool (10) of a type used to apply a steel strap (12) in a tensioned loop around a package (14) and to join the strap via a series of interlocking joints (16) comprising interlockable shoulders punched into overlapped ends of the strap (12) includes a base (60) extending longitudinally and defining a pair of recesses (70, 72). A frame (78) upstanding from the base (68) is mounted integrally to the base (68). In a mechanism for admitting the overlapped ends of the strap into the tool, for retaining the overlapped ends, and for releasing the overlapped ends from the tool, a pair of latches (100, 106) having hooked ends (102, 108) are mounted pivotably to the base (68) so as to be pivotable between closed positions wherein the latches (100, 106) are positioned with the hooked ends (102, 108) extending into the recesses (70, 72) to retain the overlapped ends between the latch (100, 106) and the base (68) and between the hooked ends (102, 108) and the frame (78) and an open positions wherein the latches are displaced angularly from their closed position to admit the overlapped ends into the tool (10) and to release the overlapped ends from the tool (10). The latches (100, 106) are biased into their closed position. Co-acting elements including a lever (70), which can be manually squeezed toward an actuating handle (40) of the strapping tool (10), and a camming member (120), which is arranged to cam the latches (100, 106), are provided for pivoting the latches (100, 106) from their closed position into their open position.