baber/WOPTO huggingface dataset:
Patent CZ-286678-B6 (CZ)
Title: Inhalator for administering powder medicaments from blister strips
Inventor: GOETTENAUER WOLFGANG
IPC: A61M15/00
Filed: 1996-06-01
Abstract: In the present invention there is disclosed an inhalator for administering powder medicaments from blister strips (5) consisting of a container film (33) with a row of individual convex blister cavities (31) whose curvature has the form of a spherical cap and containing a powder medicament, further of a cover foil (39) enclosing the blister cavities (31), whereby the inhalator is formed by a case of elongated form with at least two parts from a set comprising the case upper part (2), the case bottom part (3) a pull-out lever (9) a central part (13), case lower part (14 and a safety valve (23) being rotatably coupled with each other by means of a coupling or hinges being represented by a first hinge (16) a second hinge (17) and a suspension (24), whereby one part of the case has a square inward directing rectangular recess (30) serving as a support (29) for the blister strip (5). The case is provided at its one narrowed end with a mouthpiece (1), an inlet hole (32) situated on the opposite narrowed side and between them there is an opening (7) for direct introduction of the medicament from blister cavities (31) of the blister strip (5) put on the supports (29) in such a manner that the cover foil (39) of the inserted blister strip (5) fits close to the opening (7) and the case has means for emptying said blister strip (5) individual blister cavities (31), whereby pull-out means for emptying the individual blister cavities (31), have at least one pull-out plunger (10) with convex formed surface (37) of the plunger (10) that corresponds to the form of the convex blister cavities (31), whereby edge of the convex curved surface (37) of at least one pull-out plunger (10) is located transversely asymmetric with respect to the case axis with corresponding convex surface of the blister cavity (31).
Patent CZ-293170-B6 (CZ)
Title: Process for dosing thermal output in a combined heat and power generation system and apparatus for making the same
Inventor: RYHINER DANIEL G
IPC: F24D18/00
Filed: 1996-06-28
Abstract: The thermal output (Q) of a combined heat and power generation system is regulated by varying the speed of rotation while maintaining the position of the control means of the thermal engine in its maximum efficiency range. For that purpose, the thermal engine in its full load position or efficiency optimum is brought to a lower or higher speed of rotation exclusively by respectively reducing or increasing the electric current fed into the mains, so that the efficiency of the thermal engine is not substantially affected. The electric current may be maintained at the desired frequency by frequency converters. Apparatus for making the above-described process comprises a thermal engine (3) a generator (4) associated therewith, a rectifier (5) connected to the generator (4), a booster (6) connected to said rectifier (5), an inverter having a compound current controller (7) and being connected to the booster (6), and a control device (12).
Patent CZ-294842-B6 (CZ)
Title: Cyanoguanidines, process of their preparation and use as well as pharmaceutical compositions in which the cyanoguanidines are comprised
Inventor: HUNNECHE CHARLOTTE SCHOU
IPC: A61P43/00
Filed: 1998-05-15
Abstract: In the present invention, there are disclosed cyanoguanidines of the general formula I or tautomeric forms thereof, the attachment to the pyridine ring therein being in the position 3 or 4, in which formula Ri1 stands for one or more substituents which can be the same or different and are selected from the group consisting of: hydrogen, halogen, trifluoromethyl, carboxy, alkyl containing 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms or alkoxycarbonyl containing 1 to 4 carbon atoms in the alkoxy moiety, nitro, amino or cyano groups and Q stands for a divalent hydrocarbon radical containing 4 to 20 carbon atoms that can be straight, branched, cyclic, saturated or unsaturated and X stands for a carbonyl group, carbonylamino group, an aminocarbonyl group, an oxycarbonyloxy group, an oxycarbonyl group, a carbonyloxy group, an aminocarbonyloxy group, an aminothiocarbonyloxy group, an oxycarbonylamino group or an oxythiocarbonylamino group, Y stands for a benzylene group or phenylene group, and Ri2 stands for one or more substituents which can be the same or different and are selected from the group consisting of: hydrogen, an alkyl group containing 1 to 4 carbon atoms, a hydroxyalkyl group having 1 to 4 carbon atoms in the alkyl moiety or an alkoxy group having 1 to 4 carbon atoms, a hydroxy group, a halogen, a trifluoromethyl group, a cyano group, a carboxamido group, a sulfamoyl group, a nitro group, an amino group, a carboxy group, an alkoxycarbonyl containing 1 to 4 carbon atoms in the alkoxy moiety or a benzyloxy group; and pharmaceutically acceptable, non-toxic salts and N-oxides thereof. The present compounds are suitable in the treatment or prophylaxis of diseases characterized by abnormal differentiation and/or proliferation of cells, such as psoriasis or cancer. Claimed is also a process for preparing the above-described compounds and their use as well as pharmaceutical compositions in which these compounds are comprised.
Patent SK-281446-B6 (SK)
Title: Heterocyclic benzoylguanidine, method of their preparation, their use and pharmaceuticals them containing
Inventor: GERICKE ROLF
IPC: C07D235/18
Filed: 1995-08-21
Abstract: Heterocyclic benzoylguanidine cpds. of formula (I) and their salts are new. R1 = A, CF3, CH2F, CHF2, CN, C2F5, NO2, halo, C  IDENTICAL CH or XR4; R2, R3 = H, halo, A, XR4, CN, NO2, CF3, CH2F, CHF2, C2F5, CH2CF3, SOnR6, SO2NR4R5, Ph or OPh; R4 = H, A, 5-7C cycloalkyl, 6-8C cycloalkylmethyl, CF3, CH2F, CHF2, CH2CF3, Ph or CH2Ph; R5 = H or A; or R4+R5 = 4-5C alkylene, opt. with one CH2 replaced by O, S, NH, NA or NCH2Ph; R6 = A or Ph; Het = one or two-ringed heterocycle (satd., unsatd. or aromatic) with 1-4 N, O and/or S, bonded at N or C and opt. mono- tri-substd. with halo, CF3, A, XR4, CN, NO2 and/or carbonyloxy (sic); A = 1-6C alkyl; X = O, S or NR5; Ph = phenyl, opt. mono- to tri-substd. by A, OA, NR4R5, halo or CF3; halo = F, Cl, Br or I; n = 1-2
Patent SK-279501-B6 (SK)
Title: Process and apparatus for the production of a heart valve prosthesis
Inventor: RELIGA ZBIGNIEW
IPC: A61F2/24
Filed: 1992-05-08
Abstract: A heart valve prosthesis (1) having an annular support (1a) which has, at one of its axial ends, axially projecting support arms (4) which are distributed over the circumference and are rounded at the free end is covered with a textile covering (3), starting from a collar form thereof. The textile covering (3) is elastic and at least in one direction (A'). It is inserted into the annular support (1a) and is turned, at its two projecting axial ends (15, 16), over the outer surfaces of the support (1a). The two ends (15, 16) are then joined to one another all around by a seam (17). This seam may be concealed by a collar (2). Disclosed is also an apparatus for covering a support (1a) with a textile covering (3). The apparatus has two coaxial rings (33, 34), with a middle opening (25), attaching the support (1a) with the textile covering (3). One of the rings (33) is provided with securing means (27, 28) of one end (16) of the textile (3), whereas the second ring is provided with a grip device of the second end (15) of the textile (3).
Patent SK-282346-B6 (SK)
Inventor: PALEPU NAGESWARA R
IPC: A61K31/54
Filed: 1997-03-26
Abstract: Dihydrát monomentánsulfonátu kyseliny (E)-alfa-[2-n-butyl- 1-[(4-karboxyfenyl)-metyl]-1H-imidazol-5-yl]-metylén-2- tiofénpropiónovej; spôsoby jeho prípravy a farmaceutický prostriedok obsahujúci túto zlúčeninu, určený na blokovanie angiotenzín II receptorov a na liečenie hypertenzie, kongestívneho zlyhania srdca a zlyhania obličiek.ŕ
Patent SK-282907-B6 (SK)
Title: Nutritional supplement and use
Inventor: CAVAZZA CLAUDIO
IPC: A23L33/15
Filed: 1998-03-27
Abstract: A nutritional supplement for facilitating the adaptation of skeletal muscle in individuals undergoing programs of strenuous exercise and counteracting defatigation and weariness in asthenic individuals is disclosed, which comprises a combination of L-carnitine, acetyl L-carnitine and propionyl L-carnitine as basic active ingredients in the weight ratio 1 : 1 : 1 to 1 : 0.1 : 0.1. Optional ingredients comprise isovaleryl L-carnitine, branched-chain aminoacids and creatine and/or phosphocreatine.
Patent SK-283173-B6 (SK)
Title: Novel hydroxy and polyhydroxy derivatives of coumarin, preparation thereof and antiviral action thereof
Inventor: TRKOVNIK MLADEN
IPC: C07D311/48
Filed: 1998-10-01
Abstract: The present invention relates to novel hydroxy and polyhydroxy derivatives of coumarin fused with dialdehydes and aldehyde acids of the general formulae I, II, III and IV: wherein R1 = R2 = 4-hydroxycoumarin; R1 = R2 = 4,7-dihydroxycoumarin; R1 = R2 = 4,5,7-trihydroxycoumarin; R1 = 4-hydroxycoumarin, R2 = -CH(OH)CH3. An object of the invention are also processes for the preparation of hydroxy and polyhydroxy derivatives of coumarin fused with dialdehydes and aldehyde acids, and the antiviral action thereof. Novel hydroxy and polyhydroxy derivatives of coumarin according to the present invention exhibit antiviral action against HIV-1 virus.
Patent SK-281505-B6 (SK)
Inventor: HERR JOHN C
IPC: C07K14/705
Filed: 1997-06-30
Abstract: Monoklonálna protilátka (S19), produkovaná hybridómom ATCC, HB 12144, účinne aglutinuje spermatický povrchový glykoproteín, SAGA-1 proteín. Protilátka je použiteľná ako väzbové činidlo v spermicíde, kde má vysoký stupeň účinnosti vo väzbe potenciálnych spermií. Viazaný proteín, identifikovaný ako SAGA-1, je imunogénnom v antikoncepčnej vakcíne, rovnako ako štandardom na určenie titra protilátky po vakcinácii. Monoklonálna protilátka môže byť tiež použitá ako diagnostické činidlo na určenie prítomnosti a množstva spermií v rôznych vzorkách.ŕ
Patent CZ-297501-B6 (CZ)
Title: Process of working aluminium scrap and production line for making the same
Inventor: HAINEAIKA LADISLAV
IPC: B09B3/30
Filed: 2005-03-14
Abstract: The present invention relates to a process of working aluminium scrap into the form of a granulate used particularly as deoxidizing agent into steel melts, wherein the process is characterized in that staring material, after being classified into individual material classes, is processed in the first phase in order to provide straight and flat pieces r, which are subsequently classified to their thickness into various categories from the thinnest up to the thickest ones, and in the second phase so classified material is processed to the form of sheets, plates of straight wires that are subsequently cut and after being classified to weight, they are pressed in matrices to a selected form and size of the granulate. The invention also relates to a production line for making the above-described process wherein the line consists at least of a material selection unit (1), a primary shape processing unit (2), a secondary shape processing unit (3), at least one cutting device (4, 5), a rough pressing shop (6), an automatic dosing unit (7), an automatic pressing center (8), a packaging and filling unit (9), and a store (10) of finished products, whereby all the units are series arranged. 
Patent CZ-304478-B6 (CZ)
Title: Steel-fiber-reinforced concrete of ultrahigh strength
Inventor: Fládr Josef
IPC: C04B18/00
Filed: 2012-12-17
Abstract: The steel-fiber-reinforced concrete of ultrahigh strength with cement matrix according to the present invention comprises silicate cement, basalt aggregates, metal fibers, admixtures and additives. The amount of admixtures in the volume is given by the test results of porosity of the basalt aggregate mixture and the metal fibers. The additives are present in an amount needful for achievement of required placeability, according to the actual application. The cement matrix contains 600 to 1000 kg/me3 of silicate cement, the basalt aggregates consist of three fractions, and namely the fractions 0-4, 4-8 and 8-16 with the total weight dosage in the range of 1500 to 2000 kg/me3. The ratio of these fractions is determined based on granulometry and mineralogical composition of the actual source of the basalt aggregates. Water-cement ratio is in the range of 0.16 to 0.25. Steel fibers are composed of two fiber types being uniformly disperse in the volume of the hardened steel-fiber-reinforced concrete. The first type of the steel fibers has a rectangular cross section with the width in the range of 0.2 to 0.5 mm, the height in the range of 1.5 to 2.0 mm and the length in the range of 25 to 35 mm with strength of about 350 to about 450 MPa. The other type of the steel fibers has a circular cross section with diameter in the range of 0.08 to 0.12 mm, the length thereof is in the range of 8 to 15 mm and their strength is greater than 2000 MPa. Summation weight of the both types of steel fibers is in the range of 100 to 280 kg/me3.
Patent CZ-304553-B6 (CZ)
Title: Tamoxifen derivatives exhibiting activity against tumors, especially tumors with higher protein level HER2
Inventor: NEUŽIL JIŘÍ
IPC: A61K31/138
Filed: 2013-04-24
Abstract: In the present invention, there are disclosed mitochondrially targeted E and/or Z isomers of tamoxifen alkyl-triphenylphosphonium derivatives or mixtures thereof of the general formula I, in which n = 8 through 12 and X = Br, I, mesyl, which are used in the therapy of tumors, particularly tumors with higher level of HER2 protein as well as process for their preparation. There is also disclosed a medicament for the treatment of neoplastic diseases, which medicament comprises at least one E and/or Z isomer of tamoxifen alkyl triphenylphosphonium derivatives of the general formula I.
Patent CZ-307607-B6 (CZ)
Inventor: Látr Aleš
IPC: C12R1/645
Filed: 2015-06-30
Abstract: Přípravek k ochraně listnatých dřevin, tvořený inokulem na bázi symbiotických mykorhizních hub a inertním nosičem, jehož podstata spočívá v tom, že inokulum na bázi symbiotických mykorhizních hub sestává ze směsi inertních nosičů, na něž jsou navázány infektivní částice, s výhodou spory a/nebo fragmenty mycelia a/nebo kolonizované kořeny hostitelských rostlin, vybraných druhů symbiotických endomykorhizních hub rodů,av množství minimálně 150 částic na ml inokula, přičemž směs inertních nosičů inokula na bázi vybraných druhů symbiotických endomykorhizních hub rodů,aje směsí složenou z expandovaného keramického kameniva a zeolitu v objemovém poměru 2:1.
Patent CZ-306882-B6 (CZ)
Title: A polymer composite with natural fibres and a light-weight matrix
Inventor: Habr Jiří
IPC: D06M101/06
Filed: 2015-12-07
Abstract: The essence of the invention lies in the fact that the composite comprises from 64 to 86 wt% of a synthetic polypropylene (PP) matrix, 5 to 25 wt% of natural cellulose or coconut fibres, 4 to 6 wt% of maleic anhydride additive and 5 to 15 wt% of a gaseous component in the form of cavities. The basis of the composite is a structurally lightened polymeric matrix formed by the gaseous component (e.g. nitrogen, CO.sub.2.n., compressed air, pentane). The other components of the composite are cellulose or coconut fibres of a defined quality in terms of the impact and effects of the temperatures and stress during the fibre preparation process, the granulation process, and the further progressive processing, e.g. injection.
Patent CZ-306970-B6 (CZ)
Inventor: Kudrna Lukáš
IPC: B23Q1/76
Filed: 2016-10-06
Abstract: Univerzální otočná podpěra pro ocelové profily je určena
pro podepření dlouhých prizmatických profilů při jejich
opracovávání. Zařízení umožňuje přesné upnutí
prizmatického profilu. Zařízení se skládá z nosného
kruhového rámu (3), upínacího zařízení a polohovacího
mechanismu a je umístěno na podpěrných válcích (5),
které jsou připevněny k podvozku (6). Do zařízení je
možné profily nasouvat z boku nebo vkládat shora.
Zařízení je určeno pro profily obdélníkového i
čtvercového průřezu různých velikostí.
Patent SK-286642-B6 (SK)
Title: Structural laminate member and method for making thereof
Inventor: KENNEDY STEPHEN
IPC: B63B3/14
Filed: 2000-11-02
Abstract: A structural laminate member comprising a first metal layer (1) having a first inner surface (4) and a first outer surface (3), a second metal layer (2) having a second inner surface and (6) a second outer surface (5), whereby the second metal layer (2) being spaced apart from said first metal layer (1); a form (10) located between the first inner surface (4) and the second inner surface (6) and an intermediate layer (20) comprised of an elastomer located in the spaces between the first inner surface (4) and the second inner surface (6) not occupied by the form (10) and adhered to the first inner surface (4) and the second inner surface(6). A method of making a structural laminate member comprising the steps of: providing first and second layers in a spaced apart relationship with a form partly in contact with both metal layers located in a core cavity defined between the two plates, said form partially filling the core cavity, casting an uncured elastomer into the core cavity, and curing said elastomer so that it adheres to the metal layers.
Patent CZ-293733-B6 (CZ)
Title: Process for preparing dry animal feed
Inventor: MOLOGNI BATTISTA
IPC: A23K1/00
Filed: 1999-05-05
Abstract: The present invention relates to a process for preparing a ground dry animal feed with predetermined water content. According to the proposed process, there is added to a dry animal feed mixture an emulsion of water emulsified in a hydrophobic component comprising a lipid, a fatty acid or a mixture thereof and  having a melting point of at least 15 degC, preferably at least 20 degC, in such an amount that the animal feed will have the predetermined water content. The emulsion can be added at any time after grinding of the components included in the dry animal feed, either to a ground component or to the dry animal feed mixture before granulation, extruding or expanding, or after granulation,  extruding or expanding, or by a combination of the stated points of addition.
Patent CZ-299648-B6 (CZ)
Title: Compound, use of agent stimulating production of growth hormone, method of such stimulation and pharmaceutical composition
Inventor: PESCHKE BERND
IPC: C07K5/065
Filed: 1999-06-29
Abstract: In the present invention, there are disclosed compounds of the general formula I, in which the substituents have specific meanings, pharmaceutical compositions containing such compounds and their use in the treatment of disorders caused by lack of growth hormone.
Patent SK-286381-B6 (SK)
Title: Pressurised container for dispensing a medicament and metering valve for use with this container
Inventor: WARBY RICHARD JOHN
IPC: B65D83/00
Filed: 1999-02-19
Abstract: Apparatus is provided for dispensing medicament wherein at least a portion of one or more of the internal surfaces of components of the apparatus which come into contact with the medicament during storage or dispensing has a layer of cold plasma polymerised perfluoro-hexane bonded to a at least a portion thereof.
Patent BR-PI0111065-B8 (BR)
Inventor: ALLEN R WONS
IPC: A61M1/36
Filed: 2001-05-29
Abstract: A blood collection system has a container for holding blood and a filter communicating with the container, mutually arranged for handling as a unit. The filter (20) contains a fibrous filter medium (28) housed within two flexible sheets (32, 34) of plastic. A first seal (36) joins the sheets (32, 34) directly to the filter medium (28) inboard of the peripheral edge (40) of the filter medium (28), and a second seal (38) joins the sheets (32, 34) outboard of the peripheral edge (40) of the filter medium (28). A region (42) of the filter medium (28) extends between the first and second seals (36, 38) to cushion contact with the filter housing during handling.
Patent EP-1156875-B8 (EP)
Inventor: RAMSHAW COLIN
IPC: B01F25/74
Filed: 2000-02-17
Granted: 2003-04-09
Abstract: A reactor including a rotatable disc (3) having a surface (5) onto which reactant (15) is supplied by way of a feed (4). The disc (3) is rotated at high speed, and the reactant (15) spills over the surface (5) so as to form a film (17). A rotary fan or impeller (70) is mounted so as to cover the surface (5) and to suck a gaseous phase component across the surface (5) in a direction generally counter-current to the flow of reactant (15) across the surface. The surface (5) may be provided with features to enhance its surface area, such as a metal mesh (60), thereby helping to increase the residence time of the reactant (15) on the surface (5) and to help mixing. <IMAGE>
Patent EP-1459293-B8 (EP)
Inventor: DI GIOVANNI CORRADO
IPC: H04R1/30
Filed: 2002-08-09
Granted: 2008-08-13
Abstract: An electropneumatic acoustic horn is disclosed, comprising an electric compressor unit for generating compressed air and a sound wave generator comprising at least an acoustic chamber associated to at least a volute wound acoustic duct adapted to propagate the produced sound to the outside. Air channelling means put the compressor unit in communication with each acoustic chamber. The compressor unit and the sound wave generator are mechanically connected in a removable way by fitting slidingly a collar.
Patent EP-1850821-B8 (EP)
Title: Systeme elevateur
Inventor: BECK ADAM
IPC: A61G3/06
Filed: 2005-08-30
Granted: 2010-12-22
Abstract: La présente invention concerne un système élévateur pour un véhicule comprenant un élévateur qui est agencé pour être levé et baissé pour donner accès au véhicule et une section de plancher réglable (30) pour le véhicule qui est agencée pour être réglée entre une position d’accès à pied dans laquelle il permet l’accès au véhicule à pied, et une position d’accès d’élévateur dans laquelle il permet l’accès de l’élévateur au véhicule.
Patent EP-1741578-B8 (EP)
Inventor: HEER SIEGFRIED
IPC: B60G17/052
Filed: 2006-07-05
Granted: 2010-06-23
Abstract: The control device includes several integrated electrical control units and several electrically controllable pre-control valves (6, 7) connected to and least one air supply valve (9) with blocking valves (10, 11). The electrically controllable transverse throttle (12) separates the airbags from each other in the blocked position.
Patent EP-1903109-B8 (EP)
Inventor: DAI KEN-SHWO
IPC: C12N9/14
Filed: 2006-09-22
Granted: 2010-12-15
Abstract: The invention relates to the nucleic acid and polypeptide sequences of one novel human PPEF-1-related gene variant (PPEF-1V).  The invention also provides a process for making the polypeptides of the variant.  The invention further provides a use of the nucleic acid and polypeptide sequences of the gene variant in diagnosing T-cell lymophoblastic lymphoma.
Patent EP-2267452-B8 (EP)
Inventor: SCHOLZ CHRISTIAN
IPC: C12N15/62
Filed: 2002-06-24
Granted: 2012-11-14
Abstract: The present invention relates to the diagnosis of HIV infections. It especially teaches the production of a soluble retroviral surface glycoprotein- (or transmembrane glycoprotein)-chaperone complex and the advantageous use of a chaperone-antigen complex especially in the detection of antibodies to HIV in immunoassays, preferably according to the double antigen bridge concept, or as an immunogen. The invention also discloses soluble complexes comprising a variant of HIV-1 gp41 or a variant of HIV-2 gp36, respectively, and a chaperone selected from the peptidyl-prolyl-isomerase class of chaperones. Variants comprising specific amino-acid substitutions in the N-helical domain of HIV-1 gp41 or of HIV-2 gp36, respectively, arc also described.
Patent BR-PI0402630-B8 (BR)
Title: processo de obtenção de vacina pertussis celular menos reatogênica
Inventor: DENISE SILVINA PICCINI QUINTAS HORTON
IPC: A61K39/10
Filed: 2004-07-05
Abstract: processo de obtenção de nova vacina pertussis celular, que prevê a utilização de células de bordetella pertussis, obtidas por cultivo em fermentador, destoxificadas por formaldeído, que após tratamento com solvente orgânico originam preparações vacinais menos tóxicas e tão potentes quanto a vacina pertussis celular tradicional.