baber/WOPTO huggingface dataset:
Patent CO-5540386-A2 (CO)
Title: Sulfona-hidroxamatos aromaticos y su uso como inhibidores de proteasas
Inventor: BARTA THOMAS E
IPC: A61K31/4355
Filed: 2003-11-10
Abstract: 1.- Un compuesto o sal del mismo en el cual:el compuesto corresponde en estructura a la Fórmula 1-1:A1 se selecciona del grupo formado por -H, alquilcarbonilo, alcoxicarbonilo, carbociclilcarbonilo, carbociclilalquilcarbonilo, heterociclilcarbonilo, heterociclilalquilcarbonilo, carbocicliloxicarbonilo, carbociclilalcoxicarbonilo, aminoalquilcarbonilo, alquil(tiocarbonilo), alcoxi(tiocarbonilo), carbociclil(tiocarbonilo), carbociclilalquil(tiocarbonilo), heterociclil(tiocarbonilo), heterociclilalquil(tiocarbonilo), carbocicliloxi (tiocarbonilo), carbociclilalcoxi(tiocarbonilo), y aminoalquil(tiocarbonilo), donde cualquier miembro (excepto - H) de dicho grupo es optativamente sustituido; yA2 y A3, junto con el átomo de carbono al cual ambos están unidos, forman un heterociclilo optativamente sustituido que contiene entre 5 y 8 miembros en el anillo; yE1 se selecciona del grupo formado por -O-, -S(O)2-, -S(O)-, -S-, -N(R1)-, -C(O)-N(R1)-, -N(R1)-C(O)-, y -C(R1)(R2)-; yE2 se selecciona del grupo formado por alquilo, cicloalquilo, alquilcicloalquilo, cicloalquilalquilo, y alquilcicloalquilalquilo donde cualquier miembro de dicho grupo es optativamente sustituido; yE2 forma un enlace de al menos 2 átomos de carbono entre E1 y E3;yE3 se selecciona del grupo formado por -C(O)-, -O-(CO)-, -C(O)-O-, -C(NR3)-, -N(R4)-, -N(R4)-C(NR3)-, -C(NR3)-N(R4)-, C(O)-N(R4)-, N(R4), -C(O)-, -N(R4)-C(O)-N(R5)-, -S-, -S(O)-, -N(R4)-S(O)2-N(R4)-, -C(O)-N(R4)-N(R5)-C(O)-, -C(R4)(R6)-C(O)-, -C(R7)(R8)-; yE4 se selecciona del grupo formado por un enlace, alquilo, y alquenilo donde el alquilo es relativamente sustituido; yE5 se selecciona del grupo formado por -H, OH, alquilo, alquenilo, alquinilo, alcoxi, alcoxialquilo, carbociclilo, y heterociclilo donde cualquier miembro (excepto -H o, -OH) de dicho grupo es optativamente sustituido.
Patent CO-5560543-A2 (CO)
Inventor: JAGTAP PRAKASH G
IPC: A61P19/02
Filed: 2004-02-25
Abstract: The invention provides novel classes of substituted indeno[1,2-c]isoquinoline compounds. Pharmaceutical compositions and methods of making and using the compounds are also described.
Patent CO-5640112-A2 (CO)
Title: Combinaciones para el tratamiento de enfermedades que implican proliferacion, migracion o apoptosis celulares de celulas de mieloma, o angiogenesis
Inventor: HILBERG FRANK
IPC: A61K31/496
Filed: 2005-11-29
Abstract: 1.- Una combinación farmacéutica que comprende cantidades efectivas de:(i) un antagonista de al menos un receptor seleccionado de VEGFR1 a 3, PDGFRa y ß, FGFR 1, 2 y 3, EGFR, HER2, IGF1R, HGFR o c-kit, que es además un antagonista de un miembro de la familia de tirosin-quinasa de src, o un polimorfo, metabolito o sal farmacéuticamente aceptable del mismo; y (ii) por lo menos un agente quimioterapéutico o terapéutico natural, semi-sintético o sintético adicional, y opcionalmente adaptada para un co-tratamiento con radioterapia o radioinmunoterapia, en la forma de una preparación combinada para uso simultáneo, separado o secuencial en el tratamiento de enfermedades que impliquen proliferación, migración, o apoptosis celulares de células de mieloma, o angiogénesis.2.- La combinación farmacéutica de acuerdo con la reivindicación 1, en la cual el antagonista de al menos un receptor seleccionado de VEGFR1 a 3, PDGFRa y ß, FGFR1, 2 y 3, EGFR, HER2, IGF1R, HGFR o c-kit, que es también un antagonista de un miembro de la familia de la tirosin-quinasa de src, es un antagonista de src, Ick, Iyn, o fyn,3.- La combinación farmacéutica de acuerdo con la reivindicación 1 ó 2, en la cual el antagonista de al menos un receptor seleccionado de VEGFR1 a 3, PDGFRa y ß, FGFR1, 2 y 3, EGFR, HER2, IGF1 R, HGFR o c-kit, que es también un antagonista de un miembro de la familia de la tirosin-quinasa de src, es además un antagonista de al menos un complejo de una quinasa dependiente de ciclina con su ciclina específica o con una ciclina viral, tal como CDK1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8 y CDK9 con sus ciclinas específicas A, B1, B2, C, D1, D2, D3, E, F, G1, G2, H, I y K, o un inhibidor de la secreción de IL-6 paracrina.4.- La combinación farmacéutica de acuerdo con una cualquiera de las reivindicaciones 1 a 3, en la cual la preparación combinada es para uso en el tratamiento de enfermedades oncológicas, tales como neoplasias humanas malignas.5.- La combinación farmacéutica de acuerdo con la reivindicación 4, en la cual la preparación combinada es para uso en el tratamiento de tumores sólidos.
Patent CO-6260032-A2 (CO)
Title: Cepillo de dientes con pantalla para suministrar informacion al usuario
Inventor: JIMENEZ EDUARDO J
IPC: A46B15/00
Filed: 2010-03-12
Abstract: Se describe un instrumento de cuidado personal o cepillo dental incluye una pantalla que provee un contenido al usuario. La pantalla puede ser configurada para mostrar un contenido en un formato de imagen en espejo. El instrumento de cuidado personal puede ser configurado para operar en uno o más modos de operación. En modo de reloj, la pantalla muestra una lectura de reloj y/o calendario. En modo de temporizador, la pantalla muestra un conteo de tiempo ascendente o regresivo. En el modo conteo, la pantalla muestra un número de cepilladas en conteo ascendente o regresivo. Uno o más componentes pueden ser incluidos para configurar variables asociadas con los modos de operación, para cambiar la orientación del contenido de la pantalla entre un formato de imagen en espejo y el formato de vista hacia el frente, y para cambiar el modo particular de operación.
Patent CO-6410312-A2 (CO)
Title: Moléculas de anticuerpo que tienen especificidad por humano ox40
Inventor: LAWSON ALASTAIR DAVID GRIFFITHS
IPC: A61K39/395
Filed: 2011-08-08
Abstract: Objeto de la Invención: Moléculas de anticuerpo que tienen especificidad por determinantes antigénicos de humano 0X40 y métodos para producir dichas moléculas de anticuerpo. Características de la Invención: Anticuerpos agonistas que tienen especificidad por OX40 humano, que comprenden una cadena pesada, en donde el dominio variable de la cadena pesada comprende por lo menos un CDR que tienen la secuencia suministrada en la Figura 1(c) SEQ ID NO:1 para CDR-H1, un CDR que tienen la secuencia de la Figura 1 (c) SEQ ID NO:2 o SEQ ID NO:20 para CDR-H2 y un CDR que tiene la secuencia de la Figura 1 (c) SEQ ID NO:3 para CDR-H3.
Patent CO-6731135-A2 (CO)
Title: Método y diseño para la fragmentación de un lote de coque crudo y caliente en un recipiente receptor
Inventor: KIM RONALD
IPC: C10B39/04
Filed: 2013-07-26
Abstract: La invención se refiere a un método y a un diseño para la fragmentación de un lote de coque crudo y caliente en un recipiente receptor con segmentos de una placa movibles, siendo el lote de coque transportado en el recipiente receptor de un vagón de transferencia de superficie plana hasta una torre de apagado, donde el lote de coque se enfría hasta temperatura ambiente utilizando los segmentos de la placa movibles de modo que la estructura del coque se distienda y se formen cavidades similares a huecos en el lote de coque compacto, y, debido a estas cavidades similares a huecos, una cantidad mayor de agua pueda penetrar en el interior del lote de coque durante el proceso de apagado subsecuente, y el tiempo de apagado reducido y el consumo menor de agua para apagar el coque hacen que la eficiencia del método sea más económica, la calidad del coque sea mayor y la carga de emisión para el medioambiente sea menor. La invención también se refiere a un diseño para aplicar este método.
Patent EP-1026014-A2 (EP)
Inventor: GENTNER HARIOLF DR
IPC: B60C29/06
Filed: 2000-01-20
Abstract: After making an emergency repair of a puncture by filling the tire with a sealant, e.g. a rubber emulsion, the tire is inflated by using refrigerant gas, e.g. carbon dioxide, from the vehicle air conditioning system. A hose is attached to the refrigerant circuit via a reducing valve and pressure gauge and connected to the tire valve.
Patent EP-1026618-A2 (EP)
Inventor: SCHMIDT ANDREAS
IPC: G06K7/08
Filed: 2000-02-03
Abstract: Antenna has a first part loop (12) and second part loop (14) both in xz-plane and forming single winding, with single supply (16) and supplied at cross over point of loops. Power supply and distance apart of loops is altered according to conveyor belt speed (42) to read from transponder (20) on packet (44).
Patent EP-1037512-A2 (EP)
Inventor: BRUNKER DAVID L
IPC: H01B7/08
Filed: 2000-03-13
Abstract: A flexible circuit member includes first and second pseudo-twisted flexible
conductors on a flexible dielectric substrate. The first pseudo-twisted conductor is on a
first side of the substrate and the second pseudo-twisted conductor is on a second side of
the substrate. Each pseudo-twisted conductor includes a periodic pattern with the first
pseudo-twisted conductor being shifted longitudinally relative to the second pseudo-twisted
conductor by one half of a period of the periodic pattern. A set of first and
second additional conductors are also provided on the dielectric substrate. The first
additional conductor is on the first side of the substrate and is spaced from and generally
follows the shape of the first pseudo-twisted conductor. The second additional conductor
is on the second side of the substrate and is spaced from and generally follows the shape
of the second pseudo-twisted conductor. These first and second additional conductors
may be coupled to reference or ground potential so as to provide a grounding system for
the flexible circuit member.
Patent EP-1035263-A2 (EP)
Inventor: LEONHARDT HANS
IPC: E04B1/76
Filed: 2000-03-13
Abstract: The supporting wall (1) is hollow with an insulating layer on the outside and with a cover layer (5) applied to the insulating layer. The cover layer incorporates a flat heat-conducting layer (9) of woven mesh or metal-coated reinforcement webbing.  The insulating layer can be provided with a flat first adhesive layer onto which the heat-conductive layer is applied and then a completely covering second cover layer.
Patent EP-1074855-A2 (EP)
Inventor: MOLL GEORG
IPC: G01S7/4865
Filed: 2000-07-28
Abstract: The method involves using the light transition time technique with a periodically emitting transmitter of pulsed light and a receiver off pulsed light. The phase shift between the transmitted and received light pulses is evaluated in a time interval bounded by the period 1/f, where f is the pulse frequency. For determining transition times greater then the period, pulse transmission is additionally interrupted for a defined time interval and the number of received pulses counted during this interval. The total transition time is derived from the sum of the phase-derived time and the product of the number of received pules and the period.
Patent EP-1077366-A2 (EP)
Inventor: SCHLOSSER RUEDIGER
IPC: G01K17/06
Filed: 2000-08-02
Abstract: The device has at least one first temp. sensor (8) for determining the heating body surface temp. at least one second temp. sensor for determining the room temp. and evaluation electronics electrically connected to the temp. sensors and arranged with them in a housing that can be opened and closed. At least the first temp. sensor is mounted on a circuit board (6) carrying the evaluation electronics and the end (12) of the circuit board carrying this sensor is pressed against the heat conducting rear (4) of the housing in thermal contact by a spring element (7).
Patent EP-1080696-A2 (EP)
Inventor: ACKERMANN WERNER
IPC: A61C1/00
Filed: 2000-08-31
Abstract: Device comprises an EMF controller (19) and a voltage or RI controller (10) for controlling the electric motor (7). An OR gate logic element (18) is used to determine which controller regulates the motor. Both controllers have a theoretical input (9) and the width of the output signal (11, 21) is used to determine the electric motor control type. An Independent claim is made for a procedure for controlling an electric motor using either an EMF or RI controller.
Patent EP-1083552-A2 (EP)
Inventor: KAGAYA HIROYUKI
IPC: G11B7/08
Filed: 2000-09-06
Abstract: An optical disc unit is disclosed, comprising a
turntable on which an optical disc is placed, an optical
pickup, guide shafts for guiding the optical pickup
radially of the optical disc, first and second support
members, as well as third and fourth support members, for
supporting the guides shafts respectively, the turntable,
the optical pickup, the guide shafts, and the first to
fourth support members being disposed on a chassis, the
second and fourth support members being respectively
provided with pawl pieces spaced a predetermined gap from
end portions of the guide shafts. Near the second and
fourth support members are disposed adjust screws for
adjusting the height of end portions of the guide shafts,
as well as torsion coil springs for urging the guide shafts
elastically. When the above end portions of the guide
shafts are displaced away from upper end faces of the
adjust screws, the displacement is restricted by the pawl
pieces of the second and fourth support members.
Patent EP-1148410-A2 (EP)
Inventor: NEWMAN EDWARD G
IPC: G06F1/16
Filed: 2000-11-02
Abstract: This invention involves a user supported hands free
activated computer that controls to the extent possible the
heat generated by computer components. Heat is an extremely
important item since the computer is in contact with the
user's body. The battery used to power the computer is also
used as a heat insulating layer.
Patent EP-1081312-A2 (EP)
Inventor: WATANABE SUSUMU
IPC: E04H4/06
Filed: 2000-05-02
Abstract: In a swimming pool in which water is circulated by a pump, a
schoolboy child is liable to be absorbed into a discharge port, which is
dangerous. A sensor which has a load cell is provided at the back of
a water-permeable cover in the discharge port. If a human body of
the child is absorbed into the discharge port and contacted with the
cover, the load cell is pressed by the water-permeable cover to
transmit a signal to a control circuit in which it is determined whether
or not pressure variation applied to the sensor is normal or abnormal.
If abnormality is determined therein, an alarm is sounded to inform a
watcher of the accident and the pump is stopped to release the child
from the discharge port.
Patent EP-1052868-A2 (EP)
Inventor: DRAGONE CORRADO PIETRO
IPC: H04B10/291
Filed: 2000-05-03
Abstract: A router combines free-space and guided wave optics to drastically
increase the number of channels used in WDM transmission systems. The
two-stage router uses the partial demultiplexing characteristic of an arrayed
waveguide router (AWR) combined with a free-space optical router to fully
demultiplex an input WDM signal. The two-stage router can be used to obtain
output wavelength signals in either one- or two- dimensional arrays.
Patent EP-1079465-A2 (EP)
Inventor: MORIKAWA FUMIO
IPC: H01R9/26
Filed: 2000-07-24
Abstract: There is provided an input-output unit for serial-parallel conversion
having a simple structure and being capable of controlling a variety of devices
together by a serial signal or transmitting output signals from various sensors
together to a control system by converting them into serial signals. For this
purpose, the input-output unit comprises plural input-output blocks 1 in series
for inputting control signals to devices or for transmission of output signals
from the devices via an input-output connector 11, and a relay block 3 having
a serial terminal 32 to be connected to the control system 7 and a signal
converter 35 for converting between serial signals transmitted to and from the
control system 7 and parallel signals transmitted to and from the input-output
blocks 1 via a multipolar joint connector 33.
Patent EP-1113394-A2 (EP)
Title: Color space quantization
Inventor: SONG JUNG MIN
IPC: G06V10/56
Filed: 2000-12-20
Abstract: The present invention relates to a color space quantization descriptor
structure for performing quantization of a color space in order to search a
multimedia based on contents when multimedia feature information is color
information, particularly when the multimedia feature information is the color
information and the search is about a moving image or a still image, the color
space quantization descriptor structure according to the present invention has a
tree structure divided into a plurality steps of superior color spaces and
subordinate color spaces, and the tree structure recurrently comprises a plurality
of subordinate color spaces. Accordingly, the present invention can improve
performace of a still image and a moving image search apparatus, perform the
quantization of a n dimensional color space such as a H, S, V, RGB, HMMD color
space etc., and perform the different step quantization corresponding to each
feature.
Patent EP-1115052-A2 (EP)
Inventor: STOKES JOHN R
IPC: G06F3/038
Filed: 2000-12-19
Abstract: A computer system includes a computer input device, an expansion slot in the
input device and a magnetic disk storage drive in the expansion slot. A Universal Bus
communicates with the input devices and the mini disk drives which are in the same housing.
Patent EP-1248764-A2 (EP)
Title: Nouveau procedes destines a la metathese croisee des olefines terminales
Inventor: GRUBBS ROBERT H
IPC: C07C41/30
Filed: 2000-01-26
Abstract: L'invention concerne un procédé de métathèse croisée des oléfines terminales. Le procédé décrit la fabrication de produits à base d'oléfines disubstituées par la mise en contact d'une première oléfine terminale avec une autre oléfine terminale visant à former un dimère puis par la mise en contact du dimère avec une deuxième oléfine terminale en présence d'un catalyseur correspondant à la formule (1): dans laquelle M peut être Os ou Ru; R et R1, identiques ou différents, peuvent être hydrogène ou un groupe substitué sélectionné entre alkyle C¿1?-C20, alcényle C2-C20, alkynyle C2-C20, aryle, carboxylate C1-C20, alcoxy C1-C20, alcényloxy C2-C20, alkynyloxy C2-C20, aryloxy, alcoxycarbonyle C2-C20, alkylthio C1-C20, alkylsulfonyle C1-C20 et alkylsulfinyle C1-C20. X et X?1¿, identiques ou différents, peuvent être représentés par n'importe quel ligand anionique. L and L1, identiques ou différents, peuvent être représentés par n'importe quel donneur d'électrons.
Patent EP-1143922-A2 (EP)
Title: Two-phase hair or skin care agent containing perfume
Inventor: KOSCHIK ACHIM
IPC: A61K8/891
Filed: 2000-06-27
Abstract: A cosmetic hair or skin care agent comprising a continuous, transparent, clear or opaque, highly-viscous gel outer phase (A) and a homogeneous inner phase (B) containing a perfume oil and which can be seen through said outer phase (A), being arranged in a regular manner. Phases (A) and (B) do not automatically mix with each other during a period of contact of at least 3 months at 30°C. The inventive separation of perfume oil and carrier substances and the dosed addition of the perfume oil which is contained in the inner phase to the final product just before application in accordance with the prescribed application results in olfactory stability of said perfume oil during storage and a strong fragrance on the skin and hair.
Patent EP-1115436-A2 (EP)
Inventor: VINCI LUCA
IPC: B01D65/00
Filed: 2000-07-27
Abstract: A filtration unit is disclosed for a dialysis machine. The unit includes a casing with a number of first connecting elements and a support provided with a number of second connecting elements. Structure is provided for locking the filter on the support when the first and second connecting elements engage each other. The lock structure may include a pair of slides movable between a locking position, in which locking parts interact with stopping portions, and a release position, in which the filter is not locked to the support. An elastic structure may be provided for resiliently urging the slides into the locking position.
Patent EP-1119217-A2 (EP)
Inventor: UKON SHINICHI
IPC: H04L47/80
Filed: 2001-01-17
Abstract: An asynchronous transfer mode connection band control
system in a system for transmitting and receiving an asynchronous
transfer mode cell utilizing an asynchronous transfer mode
network, has data storage means for storing a connection band
of a preferential switched virtual connection having high
preference in the asynchronous transfer mode network being
stored preliminarily as a band acquiring data and storing
acquired band data of a switched virtual connection currently
established connection, and connection band control means for
performing control of connection band on the basis of a total
number of bands derived by a sum of the band acquiring data
and the acquired band data stored in the data storage means.
Patent EP-1124063-A2 (EP)
Inventor: SCHULZ ULRICH
IPC: F15B13/01
Filed: 2001-01-31
Abstract: The pilot-controlled non-return valve (10), in a hydraulic control system, has a seal (16) which wholly surrounds the sealing ball (15) and seals the control line (11) from the two valve connections (12,13). The second valve connection (13) opens into the valve between the seal (16) and the valve seat (14). The seal (16) is contained within a groove (18), open inwards, at the level of the equator of the sealing ball (15) in relation to the direction of the ball stroke movements (17).
Patent EP-1134552-A2 (EP)
Inventor: KATAYAMA MUTSUMI
IPC: G01C21/36
Filed: 2001-02-21
Abstract: The invention provides a mobile navigation apparatus for
facilitating the decision as for in which direction a
vehicle should be headed when it has moved to a location
deviated from a planned travel route. 
   When the current location of a vehicle
is at a location deviated from the planned travel route,
a straight line connecting the current location to a
shortest distance location on the planned travel route,
the straight line making the distance shortest from the
current location to the planned travel route is displayed
on display means along with the map information stored in
map information storage means and the vehicle's current
positional information.
Patent EP-1136804-A2 (EP)
Title: Piezoelectric torque sensing
Inventor: KOVACICH JOHN A
IPC: G01L3/10
Filed: 2001-03-02
Abstract: A disk-like piezoelectric crystal element having an axis of maximum strain sensitivity has
a pair of electrodes sputter deposited on opposite faces. A pair of annular resilient spacers are
disposed one over each electrode on the piezoelectric element and a cover is disposed over each
spacer to form an air gap respectively between the cover and the electrode and forms a transducer
subassembly. A torsion member to be subjected to an applied torque has an area prepared,
preferably recessed and the subassembly disposed in the recess with the axis of maximum strain
sensitivity oriented at about 45° to the torque axis. The subassembly has electrical leads attached
and is potted in the recess with strain transmitting potting compound such as epoxy. The
electrical leads are coupled to an external oscillator circuit via a rotary variable capacitive
coupling. The circuit determines the changes in the heterodyned frequency of the oscillator and
the resonant frequency of the strained piezoelectric crystal element as an indicator of torsional
strain in the torsion element. The variable capacitance provides an indication of rotary angular
position.