baber/WOPTO huggingface dataset:
Patent AU-2018264053-A1 (AU)
Title: Use of pyrazolopyrimidine derivatives for the treatment of pi3kdelta related disorders
Inventor: LI YUN-LONG
IPC: A61K31/5377
Filed: 2018-11-14
Abstract: The present application provides methods of treating PBK6 related disorders using compounds of Formula (I): or pharmaceutically acceptable salts thereof. Cy
Patent AU-2018273799-A1 (AU)
Title: Novel murine parvovirus and uses therefor
Inventor: ROEDIGER BEN
IPC: C12N15/86
Filed: 2018-05-25
Abstract: The present disclosure relates to a novel murine parvovirus, sequences encoded thereby, and applications therefor. In one embodiment the disclosure provides a method for detecting the presence of a parvovirus in a sample, comprising detecting one or more nucleic acids or polypeptides derived from the parvovirus, or antibodies against the parvovirus, in the sample. Also provided are vectors and host cells comprising sequences encoded by the parvovirus and related sequences. Also provided are animal models of kidney disease associated with infection by the parvovirus.
Patent AU-2018303701-A1 (AU)
Title: Nebulizer and container
Inventor: WUTTKE GILBERT
IPC: A61M15/00
Filed: 2018-07-23
Abstract: A nebulizer (1) for nebulizing a liquid (2) from a container (3) and such a container are proposed. The nebulizer comprises a fluid pump (5) for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The container comprises an air pump (30) with a piston / cylinder arrangement (31, 32) for pressurizing the liquid in the container to help withdrawing the liquid from the container. A control valve (44) limits the air pressure acting on the liquid in the container to a maximum value above the ambient pressure independently from a filling level of the container with the liquid.
Patent AU-2018335098-A1 (AU)
Title: Electrolyser arrangement
Inventor: HANEBUTH MARC
IPC: C25B9/19
Filed: 2018-09-13
Abstract: The invention relates to an electrolyser arrangement with at least one electrolytic cell, comprising two electrodes, namely an anode and a cathode, each of the two electrodes being in contact with an electrode compartment for filling with a liquid electrolyte, the two electrode compartments being separated by a membrane and a conveying device being provided, one for each of the two electrodes, for conveying the electrolyte in each case in a circuit, a cathode circuit and an anode circuit, through the electrode compartment via at least one collection vessel per circuit and back into the electrode chamber. The invention is characterised in that a device is provided outside the electrolytic cell, for conveying an auxiliary volume flow between the cathode circuit and the anode circuit.
Patent AU-2018348165-A1 (AU)
Title: Neoantigen identification using hotspots
Inventor: BULIK-SULLIVAN BRENDAN
IPC: G01N33/574
Filed: 2018-10-10
Abstract: A method for identifying neoantigens that are likely to be presented on a surface of tumor cells of a subject. Peptide sequences of tumor neoantigens are obtained by sequencing the tumor cells of the subject. The peptide sequence of each of the neoantigens is associated with one or more k-mer blocks of a plurality of k-mer blocks of the nucleotide sequencing data of the subject; The peptide sequences and the associated k-mer blocks are input into a machine- learned presentation model to generate presentation likelihoods for the tumor neoantigens, each presentation likelihood representing the likelihood that a neoantigen is presented by an MHC allele on the surfaces of the tumor cells of the subject. A subset of the neoantigens is selected based on the presentation likelihoods.
Patent AU-2018367187-A1 (AU)
Title: System and method for dialog session management
Inventor: BILAC MIRIAM
IPC: G10L15/22
Filed: 2018-11-15
Abstract: A robot or other conversational agent determines whether a human interlocutor has ceded the conversational floor by detecting the absence of a particular speech characteristic such as the introduction of filler speech at the end of an utterance, and the presence of a characteristic physical behaviour, such as the interlocutor returning their gaze to a focal point of the conversion, such as the robot's face, during a specified time window after the end of the utterance. Where this combination of characteristics is detected, the robot can determine that the conversational floor is open and that a response may be appropriate. This may trigger a conversational response for example via voice or text.
Patent AU-2018372917-A1 (AU)
Title: Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof
Inventor: NOT GIVEN
IPC: A61K31/661
Filed: 2018-11-19
Abstract: The disclosure relates to the treatment of primary and metastatic cancer using radiation. Specifically, the disclosure relates to methods providing for the selective accretion of cytoprotective agent in tissues and/or organs, sensitive to radiation that are adjacent to malignant tumors prior to radiation of the tumors at a dose that otherwise would be toxic to the tissues and/or organs, but are necessary to achieve ablative outcome on the tumors.
Patent AU-2018373464-A1 (AU)
Title: 6,7-dihydropyrazolo[1,5-a] pyrazinone derivative and medical use thereof
Inventor: IKUMA YOHEI
IPC: A61P25/04
Filed: 2018-11-22
Abstract: Provided are: a compound that is useful for the prevention of and/or as a treatment agent for a disease in which a group II mGlu receptor is involved; and a medical application of said compound. Provided is a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. (In the formula, R
Patent AU-2018390366-A1 (AU)
Title: Process for producing methanol and ammonia
Inventor: INGHAM ALAN
IPC: C07C29/151
Filed: 2018-11-29
Abstract: A process for the co-production of methanol and ammonia is described comprising the steps of: (a) forming a first synthesis gas stream by reacting a first portion of a hydrocarbon feedstock and steam in a steam reformer, (b) forming a second synthesis gas stream in parallel to the first synthesis gas stream by reacting a second portion of the hydrocarbon feedstock with an oxygen-containing gas and steam in an autothermal reformer, (c) synthesising methanol from a first process gas comprising the first synthesis gas stream, and (d) synthesising ammonia from a second process gas prepared from the second synthesis gas stream, wherein a purge stream containing hydrogen is recovered from the methanol synthesis step (c) and a portion of the purge gas stream is fed to the autothermal reformer and/or the second synthesis gas in step (b).
Patent WO-2020113272-A1 (WO)
Title: Refractive scanning interferometer
Inventor: RODD-ROUTLEY SELENE
IPC: G01J9/02
Filed: 2019-12-04
Abstract: The present invention relates to a refractively-scanning interferometer comprising an aperture that receives an incident light beam at a receiving angle, a beam splitter configured to split the incident light beam into a first beam and a second beam, a first and a second reflector arranged to reflect the first beam and second beam, respectively, towards a combining optical element, and a refractive Optical Path Difference (rOPD) assembly interposed between the beam splitter and the first reflector, wherein the rOPD Assembly refracts the first light beam an even number of times with induced phase discrepancy being a vector sum of a first phase discrepancy induced by a first refraction and a second phase discrepancy induced by a second refraction, the rOPD Assembly being configured such that the first phase discrepancy is substantially opposite in direction to the second phase discrepancy, a portion of the first and second phase discrepancies cancelling one another out to decrease magnitude of the phase discrepancy.
Patent AU-2019202194-A1 (AU)
Title: Construction method, work machine control system, and work machine
Inventor: TAIRA TOMOHIRO
IPC: E02F9/20
Filed: 2019-03-29
Abstract: Docket NoPKOA-17769-US,DEAU: Final draft A work machine control system includes a shape detection unit and a construction information generation unit. The shape detection unit detects an object to be 5 constructed and outputs shape information representing a three-dimensional shape of the object. The construction information generation unit acquires the shape information from the shape detection unit and determines, using the shape information, target construction information as a 10 target of construction of the object to be constructed.
Patent AU-2019202422-A1 (AU)
Title: Multi-position load detection systems and methods
Inventor: TRACY ERIC C
IPC: B66F9/20
Filed: 2019-04-08
Abstract: The present disclosure provides systems and methods for detecting a load on at least one fork of a material handling vehicle. The systems and methods can comprise a housing; at least one sensor positioned within the housing; a sensor arm pivotally coupled to the housing; at least one sensor flag integral with or coupled to the inside of the sensor arm; and wherein when the sensor arm pivots inward toward the housing the at least on sensor flag triggers the at least one sensor to identify at least a first load position and a second load position. Start Indicate to 904 Receive First Signal Material Handling 928 From First Sensor Vehic ngTo ards The Load 908 Determine That a Load Is In a First 932 Load Position Receive Command To Raise Forks 912 Indicate That the Load Is In The First93 Indicate to Load Position Raise Forks of 936 940 Material Handling Material Handling Vehicle To Cease Vehicle Advancing Towards The Load Receive Second Signal From SecondSensor Receive Command To Raise Forks 920 Determine That The Load Is In a Second Load Position 948 Raise Forks of ItI Material Handling Indicate That The Vehicle 924 Load Is In The Second Load Position
Patent AU-2019203510-A1 (AU)
Title: Method and apparatus for use in the production of a surgical guide
Inventor: DARWOOD ALASTAIR
IPC: A61B17/17
Filed: 2019-05-20
Abstract: Method and Apparatus for use in the Production of a Surgical Guide A method of producing a modification plan for producing a surgical guide from an impression element (16) includes: obtaining surface data representing a configuration of a surface of an impression element (16) providing an impression of a surgical site; obtaining image data of a patient's anatomy; obtaining surgical plan data providing a surgical plan with respect to features in the image data representing anatomical features of the patient's anatomy; registering the impression element (16) using the surface data and the image data with anatomical features of the patient's anatomy; producing a modification plan from the surgical plan data using the registration of the impression element (16) with anatomical features of the patient's anatomy, the modification plan being a plan for modifying the impression element. Figure 2 to accompany abstract. WO 2015/075423 PCT/GB2014/053304 Fig. 2
Patent AU-2019203718-A1 (AU)
Title: Method of and system for inferring user intent in search input in a conversational interaction system
Inventor: BARVE RAKESH
IPC: G06F40/237
Filed: 2019-05-28
Abstract: Abstract A method of inferring user intent in search input in a con-versational interaction system is disclosed. A method of inferring user in -tent in a search input includes providing a user preference signature that describes preferences of the user, receiving search input from the user in-tended by the user to identify at least one desired item, and determining that a portion of the search input contains an ambiguous identifier. The ambiguous identifier is intended by the user to identify, at least in part, a desired item. The method further includes inferring a meaning for the ambiguous identifier based on matching portions of the search input to the preferences of the user described by the user preference signature and selecting items from a set of content items based on comparing the search input and the inferred meaning of the ambiguous identifier with metadata associated with the content items.
Patent AU-2019206039-A1 (AU)
Title: Afucosylated anti-FGFR2IIIb antibodies
Inventor: HARDING THOMAS
IPC: A61K39/00
Filed: 2019-07-17
Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided. 11504358_1 (GHMatters) P101838.AU.1
Patent AU-2019217365-A1 (AU)
Title: Breathable gas and water hose apparatus
Inventor: REEDY PAT J
IPC: A62B7/02
Filed: 2019-02-04
Abstract: The present invention provides a system which allows a hose apparatus to be used to deliver water and air to the user at all times, eliminating the need for users to rely on breathable gas supplied by tanks. The invention includes the use of a breathable gas hose in the interior of the jacket of the water hose such that both breathable gas and water are delivered through the hose apparatus simultaneously. The breathable gas hose is protected within an outer jacket surrounding the water hose. The system allows for easy connect and disconnect of the air supply to the user's breathing apparatus and can be used with standard self-contained breathing apparatus (SCBA) typically used by firefighters. The system, however, overrides the SCBA system such that the user does not have to manually switch between the breathable gas and water hose apparatus and an SCBA system.
Patent AU-2019219857-A1 (AU)
Title: Multiphase pump
Inventor: BOURNE MATTHEW
IPC: F04B47/06
Filed: 2019-08-23
Abstract: Abstract: A multiphase pump is proposed for conveying a multiphase process fluid from a low pressure side (LP) to a high pressure side (HP), comprising a housing 5 (2) having a pump inlet (3) and a pump outlet (4) for the process fluid, further comprising an inlet annulus (5) designed for receiving the process fluid from the pump inlet (4), a discharge annulus (6) designed for discharging the process fluid into the pump outlet (4), a pump rotor (7) for rotating about an axial direction (A) arranged within the housing (2), with the pump rotor (7) 10 being designed for conveying the process fluid from the inlet annulus (5) to the outlet annulus (6), and a return line (9) for returning the process fluid from the high pressure side (HP) to the low pressure side (LP), wherein the return line (9) comprises an inlet (91) for receiving the process fluid, an outlet (92) for discharging the process fluid and a control valve (93) for opening and 15 closing the return line (9), and wherein the inlet (91) of the return line (9) is arranged directly at the discharge annulus (6). (Fig. 1) Fig.1 93_ 0 91 _ _ _ _
Patent AU-2019240548-A1 (AU)
Title: Socket drive improvement
Inventor: EGGERT DANIEL M
IPC: B25B13/06
Filed: 2019-09-30
Abstract: Sockets, for example, hexagon sockets, dodecagonal sockets, and splined sockets, that have inner surface geometries adapted to engage a flank of a fastener at a point away from a corner of the fastener. In general, the sockets engage the flank of the fastener at a distance of about 30 to 60 percent of half a length of the flank away from the corner of the fastener. This increases the strength and life of the socket, reduces a risk of the fastener becoming locked or stuck in the socket, and reduces the risk of the fastener being stripped or the socket slipping on the fastener. Figure 1. 11716945 1 (GHMatters) P98022.AU.4 GSEE FIG. A i~o 112 D1
Patent AU-2019258844-A1 (AU)
Title: Compositions and articles comprising complexes of 1-methylcycloproprene and alpha-cyclodextrin
Inventor: WOLAN ANDRZEJ
IPC: A01N25/10
Filed: 2019-04-26
Abstract: Compositions comprising complexes of 1-methylcyclopropene and α-cyclodextrin, and articles including the composition, are provided. Methods for using the compositions and articles in delaying the maturation of fruits, vegetables, and plants are also provided.
Patent AU-2019271312-A1 (AU)
Title: Ion beam device and method for generating heat and power
Inventor: BLAKE RUSSELL
IPC: G21B3/00
Filed: 2019-05-11
Abstract: A device and method which generate heat and electrical power by controlling the density, focus, and speed of an ion beam from a low-power plasma (107) in a plasma chamber (106) from which the ion beam (111) is extracted into a reaction chamber (103) optionally to enrich a target (102) into a target hydride, to initiate and sustain heat and optionally a cold fusion reaction in said target, recovering heat energy (105) from said reaction to provide heating and/or to generate electrical power (119), optionally to replenish the target with additional ionic fuel and/or deposit additional target material when additional heat is not required, whilst during heating and optional enrichment/deposition and cold fusion cycles extracting excess fuel from the chambers to recombine if necessary with any fuel byproduct from the source fuel (109) to then reuse as source fuel.
Patent AU-2019277171-A1 (AU)
Title: Anti-abeta antibodies and uses thereof
Inventor: SHIE FENG-SHIUN
IPC: C07K16/46
Filed: 2019-05-29
Abstract: An isolated antibody, comprising a light-chain CDR1 (L-CDR1) having the sequence of SEQ ID NO: 1, SEQ ID NO: 7, or SEQ ID NO: 14; a light-chain CDR2 (L-CDR2) having the sequence of SEQ ID NO: 2 or SEQ ID NO: 15; a light-chain CDR3 (L-CDR3) having the sequence of SEQ ID NO: 3, SEQ ID NO: 8, SEQ ID NO: 21, or SEQ ID NO: 24; a heavy-chain CDR1 (H-CDR1) having the sequence of SEQ ID NO: 4, SEQ ID NO: 9, SEQ ID NO: 11, SEQ ID NO: 16, or SEQ ID NO: 25; a heavy-chain CDR2 (H-CDR2) having the sequence of SEQ ID NO: 5, SEQ ID NO: 12, SEQ ID NO: 17, SEQ ID NO: 19, SEQ ID NO: 22, or SEQ ID NO: 26; and a heavy-chain CDR3 (H-CDR3) having the sequence of SEQ ID NO: 6, SEQ ID NO: 10, SEQ ID NO: 13, SEQ ID NO: 18, SEQ ID NO: 20, SEQ ID NO: 23, or SEQ ID NO: 27, wherein the antibody specifically binds to Αβ
Patent AU-2019283826-A1 (AU)
Title: Medial column fusion plates
Inventor: KOBAYASHI KENNETH I
IPC: A61B17/80
Filed: 2019-12-17
Abstract: Abstract A medial column bone Plate includes (a) first portion (FP) which, when Plate is positioned along a medial column of a foot in a desired position, extends along a navicular, FP including first 5 variable angle holes extending therethrough, each of first variable angle holes receives a bone fixation element therethrough at a user-selected angle relative to a central axis thereof; (b) second portion (SP) extending distally from FP so that when Plate is in the desired position, SP extends along a medial cuneiform, SP including at least one second variable angle hole receiving the element therein and a first compression slot extending therethrough; and (c) third portion (TP) 0 extending distally from SP so that TP extends along a first metatarsal of the medial column in the desired position, TP including a third variable angle hole receiving the element therein and a second compression slot extending therethrough.
Patent AU-2019301511-A1 (AU)
Title: Stand alone dispensing pouch
Inventor: BREGEON VERONIQUE
IPC: A61D7/00
Filed: 2019-07-03
Abstract: The present invention relates to a stand-up pouch, for holding and dispensing fluid veterinary formulations, made of a flexible film material.
Patent AU-2019322492-A1 (AU)
Title: Removable power assist for manual wheelchair
Inventor: PESKIN EVAN
IPC: A61G5/02
Filed: 2019-04-26
Abstract: Disclosed is a device for converting a manual wheelchair into an electronic wheelchair is provided. The device includes a joystick, a communication unit, a motor, a retractable friction roller, an engagement unit and a power source. The joystick is operably connected to a communication unit. The communication unit is operably connected to a motor. The motor includes an axle connected to a rotor. The retractable friction roller is mounted on the axle. The roller is placed in contact with a wheel of a manual wheelchair. The engagement unit is attached to the manual wheelchair to detachably attach the friction roller and the wheel. The power source is operably connected to the motor and the joystick.
Patent AU-2019338618-A1 (AU)
Title: Casting equipment
Inventor: HÅKONSEN ARILD
IPC: B22D11/18
Filed: 2019-08-19
Abstract: The invention provides a casting equipment (1) for casting melt (15) into a cast product (80) comprising a supply reservoir (10) for supplying the melt (15), a distribution reservoir (20), a casting apparatus (25) having a melt inlet connected to the distribution reservoir (20) for producing the cast product (80), a supply conduit (30) fluidly connecting the supply reservoir (10) and the distribution reservoir (20), an electromagnetic pump (35) provided on the supply conduit (30) and operable to generate a force in the melt (15) in the supply conduit (30), a level sensor (40) for measuring a level of the melt (15) in the distribution reservoir (20) and/or in the supply reservoir (10), a controller operably connected to the pump (35) and the level sensor (40), wherein the supply conduit (30) is sealed or sealable from a pressure of the atmosphere, wherein the controller is configured to control an operation of the pump (35) based on a level signal from the level sensor (40), and wherein, at least during a steady-state casting operation, the casting equipment is configured such that the supply conduit (30) defines a flow path that has a point that is higher than a surface of the melt in the supply reservoir (10) and/or the distribution reservoir (20), and the pump (35) is operated such that the metal level in the distribution reservoir (20) is at a predefined level such as to control a pressure of the melt (15) in the melt inlet of the casting apparatus (25).
Patent AU-2019354743-A1 (AU)
Title: Engineered genetic modulators
Inventor: MILLER JEFFREY C
IPC: C12N15/113
Filed: 2019-10-02
Abstract: Genetic modulators comprising two or more artificial transcription factors for use in specific and active modulation of gene expression are provided.
Patent AU-2019380035-A1 (AU)
Title: Compounds that selectively and effectively inhibit Hakai-mediated ubiquitination, as anti-cancer drugs
Inventor: FIGUEROA CONDE-VALVÍS ANGÉLICA
IPC: A61P35/00
Filed: 2019-11-15
Abstract: The present invention provides a class of compounds, which includes enantiomers and pharmaceutically acceptable salts thereof, that selectively and effectively inhibit Hakai-mediated ubiquitination, preferably without affecting Hakai protein levels, thereby representing excellent anti-cancer drugs useful in the treatment of a variety of cancers, such as carcinomas, in particular, tumors arising from the epithelial layers of the gastrointestinal track including month (oral cancer), esophagus, stomach, and small and large intestines (such as rectal or colon cancer). It also includes skin cancer, mammary gland (breast cancer), pancreas cancer, lung cancer, head and neck cancer, liver cancer, ovary cancer, cervix cancer, uterus cancer, gallbladder cancer, penile cancer, and urinary bladder cancer (such as renal, prostate or bladder cancer).
Patent AU-2019385370-A1 (AU)
Title: Application of chidamide
Inventor: LU XIANPING
IPC: A61P35/00
Filed: 2019-11-18
Abstract: The present invention relates to the technical field of medicine, and discloses an application of chidamide. The present invention provides the application of a therapeutic schedule for using chidamide in the treatment of B cell lymphoma, and verifies by clinical test the outstanding effect of chidamide monotherapy for diffuse large B cell lymphoma and recurrent or refractory follicular lymphoma accompanied by specific epigenetic regulation gene mutation. The application can treat B cell lymphoma patients more effectively.
Patent AU-2019405925-A1 (AU)
Title: Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors
Inventor: BRENNEMAN JEHROD BURNETT
IPC: A61P35/00
Filed: 2019-12-19
Abstract: The present disclosure provides compounds having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein X