baber/WOPTO huggingface dataset:
Patent NZ-591437-A (NZ)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: G01N33/53
Filed: 2009-08-28
Abstract: NZ 591437 Disclosed is a method for evaluating one or more future acute changes in renal function of a subject. The method comprises performing one or more assays configured to detect soluble p-selectin in a body fluid sample obtained previously from the subject to provide one or more assay results, each assay result comprising a measured level of soluble p-selectin in the body fluid sample, comparing a measured concentration of soluble p-selectin to a threshold concentration of soluble p-selectin; and assigning an increased likelihood of an acute reduction in renal function occurring within 30 days from the time at which the body fluid sample was obtained from the subject when the measured concentration is above the threshold, relative to a likelihood thereof when the measured concentration is below the threshold; or assigning a decreased likelihood of an acute reduction in renal function occurring within 30 days from the time at which the body fluid sample was obtained from the subject when the measured concentration is below the threshold, relative to a likelihood thereof when the measured concentration is above the threshold.
Patent NZ-593106-A (NZ)
Title: Modified protozoan expressing at least two variable surface proteins (vsp), a vaccine comprising it and procedures, uses, and methods thereof
Inventor: LUJAN HUGO DANIEL
IPC: A61K35/68
Filed: 2009-12-02
Abstract: Disclosed is a modified Giardia lamblia parasite wherein a gene encoding Dicer, a gene encoding RNA-dependant RNA-polymerase (RdRP), or both have been silenced, and wherein said modified Giardia lamblia comprises simultaneous expression on its surface of more than one variable surface protein (VSP).
Patent NZ-599639-A (NZ)
Title: Use of ferroquine in the treatment or prevention of malaria
Inventor: FRAISSE LAURENT
IPC: A61K31/295
Filed: 2010-10-29
Abstract: The present disclosure relates to the use of ferroquine(7-chloro-N-[[2-[(dimethylamino)methyl]cyclopenta-1,4-dien-1-yl]methyl]quinolin-4-amine;cyclopenta-1,3-diene;iron(2+)), or a pharmaceutically acceptable salts thereof for treating and/or preventing infections caused by a parasiteof the species Plasmodium Vivax, the infection of blood cells caused by Plasmodium vivax at the stages of parasitic growth of the immature trophozoite “ring stage” and of the mature trophozoite. In particular use is beneficial in patients deficient in glucose-6-phosphate dehydrogenase.
Patent NZ-599751-A (NZ)
Title: Treatments for gastrointestinal disorders
Inventor: FRETZEN ANGELIKA
IPC: C07K7/08
Filed: 2010-11-09
Abstract: Disclosed is a peptide or a pharmaceutically acceptable salt thereof wherein the peptide comprises the amino acid sequence Xaa1 Xaa2 Xaa3 Xaa4 Cys5 Xaa6 Xaa7 Xaa8 Cys9 Asn10 Pro11 Ala12 Cys13 Xaa14 Gly15Xaa16 Xaa17, or a pharmaceutically acceptable salt thereof; wherein Xaa1 is Asn, D-Asn, Gln, D-Gln, Pro, Ala, beta-Ala, D-Ala, Val, D-Val, Gly, Thr, D-Thr, Asp, D-Asp, gamma-carboxylated Asp, Glu, D-Glu, gamma-carboxylated Glu, alpha-aminosuberic acid (Asu), alpha-aminoadipic acid (Aad), alpha-aminopimelic acid (Apm), or is absent; Xaa2 is Asp, gamma-carboxylated Asp, Glu, gamma-carboxylated Glu, Asu, Aad, Apm, or is absent; Xaa3 is Asp, gamma-carboxylated Asp, Glu, gamma-carboxylated Glu, Asu, Aad, Apm, or is absent; Xaa4 is Cys or D-Cys; Xaa6 is P-Ser, P-Thr, P-homo-Ser, 4-hydroxyvaline phosphate, P-homo-Thr, P-Cys or P-Tyr; Xaa7 is Tyr, Leu, Phe or Ile; Xaa8 is Cys or D-Cys; Xaa14 is Thr, Ala or Phe; Xaa16 is Cys or D-Cys; and Xaa17 is Tyr, D-Tyr, or is absent; wherein: if Xaa1 is present, Xaa1 may be modified on its amino group by methyl, ethanedioic acid, propanedioic acid, butanedioic acid, pentanedioic acid, hexanedioic acid, heptanedioic acid or octanedioic acid; if Xaa1 is absent and Xaa2 is present, then Xaa2 may be modified on its amino group by methyl, ethanedioic acid, propanedioic acid, butanedioic acid, pentanedioic acid, hexanedioic acid, heptanedioic acid or octanedioic acid; or if both Xaa1 and Xaa2 are absent, then Xaa3 may be modified on its amino group by methyl, ethanedioic acid, propanedioic acid, butanedioic acid, pentanedioic acid, hexanedioic acid, heptanedioic acid or octanedioic acid. Also disclosed is the use of the peptide to treat gastrointestinal disorders.
Patent NZ-606893-A (NZ)
Title: Amine and amine oxide surfactants for controlling herbicide spray drift
Inventor: LIU LEI
IPC: A01N57/20
Filed: 2011-09-14
Abstract: Disclosed herein are aqueous concentrate compositions comprising from about 5 to about 40% by weight of a water soluble salt of glyphosate, and from about 5 to about 40% by weight of a water soluble salt of at least one auxinic herbicide such as triclopyr, 2,4-D and dicamba, and from about 1 to about 20% by weight of a tertiary amine oxide surfactant. Also disclosed are methods for reducing spray drift during the application of an aqueous herbicide composition containing glyphosate and an auxinic herbicide comprising incorporating into the mixture from about 0.02 to 2% by weight of a tertiary amine oxide surfactant.
Patent NZ-611022-A (NZ)
Title: Mold and mildew stain removing solution
Inventor: ROSEMARY GAUDREAULT
IPC: C11D3/43
Filed: 2013-05-23
Abstract: Disclosed a solution when used for removing mould (mold) and mildew stain comprising: a surfactant selected from the group consisting of alcohol ethoxylates, alkyl sulfates, alkyl ether sulfates, alpha olefin sulfonates, alkyl phosphates, alkyl amidopropyl betaines, alkyl betaines, amphoacetates, amphoproprionates, amphosulfonates, amine oxides, alkanolamides, sulfosuccinates, and sultaines; said surfactant comprising from about 1 wt. % to about 8 wt. % of the solution; an amine oxide hydrotrope, independent from said surfactant; said hydrotrope comprising from about 1 wt. % to about 5 wt. % of the solution; a glycol ether solvent, independent from said surfactant; said solvent comprising from about 0.5 wt. % to about 5 wt. % of the solution; and a chelating agent; said chelating agent comprising from about 0.25 wt. % to about 4.25 wt. % of the solution, wherein the pH of the solution ranges from about 9.2 to about 9.6. Also disclosed is a solution when used for removing mould and mildew stains comprising: a surfactant comprising an alcohol ethoxylate, in an amount from about 1 wt. % to about 8 wt. % of the mould and mildew stain removing solution; an amine oxide hydrotrope (such as lauramine oxide) independent from the surfactant, in an amount from about 1 wt. % to about 5 wt. %; a solvent comprising a glycol ether independent from the surfactant, in an amount from about 0.5 wt. % to about 5 wt. %; one or more chelating agents (such as sodium gluconate or salts of methyl glycine diacetic acid), in an amount from about 0.25 wt. % to about 4.25 wt. %; a diluent, in an amount from about 75 wt. % to about 97 wt. %; one or more preservatives, in an amount from about 0.25 wt. % to about 3 wt. %; and a fungicide, in an amount from about 0.25 wt. % to about 3 wt. %, wherein the pH of the solution ranges from about 9.2 to about 9.6.
Patent NZ-614610-A (NZ)
Title: Heterocyclic compounds for the inhibition of pask
Inventor: MCCALL JOHN M
IPC: A61P3/00
Filed: 2012-03-02
Abstract: Disclosed herein are new 3-Amino Quinoxaline-6-Carboxylic Acid compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting purine-analog sensitive kinase (PASK) activity in a human or animal subject, also provided for is the treatment of diseases such as diabetes mellitus. Compounds of the disclosure include: (R)-2-(4-Fluorophenyl)-3-(2-(trifluoromethyl)pyrrolidin-1-yl)quinoxaline-6-carboxylic acid, (R)-2-(Benzo[d][1,3]dioxol-5-yl)-3-(2-methylpyrrolidin-1-yl)quinoxaline-6-carboxylic acid, (S)-2-(1H-Indol-5-yl)-3-(3-methylmorpholino)quinoxaline-6-carboxylic acid, 3-(Azepan-1-yl)-2-(1H-indazol-5-yl)quinoxaline-6-carboxylic acid, and (S)-2-(4-Fluorophenyl)-3-(3-methylmorpholino)quinoxaline-6-carboxylic acid.
Patent NZ-616395-A (NZ)
Title: Androgen receptor modulating carboxamides for the treatment of cancer
Inventor: TÖRMÄKANGAS OLLI
IPC: C07D513/04
Filed: 2012-04-20
Abstract: Provided are cyano-phenyl-pyrazole carboxamide derivative compounds of the general formula (I) or the general formula (II), wherein the variables are as defined in the specification. Examples of the compounds include (S)-N-(1-(3-(3-Chloro-4-cyano-2,5-difluorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-2-methyl-1H-imidazole-5-carboxamide and (S)-N-(1-(3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(2-hydroxy-2-methylpropyl)-1H-pyrazole-3-carboxamide. The compounds are androgen receptor (AR) antagonists. The compounds may be useful in the treatment of prostate cancer.
Patent NZ-622796-A (NZ)
Title: Water heater
Inventor: PATRICK PUSSELL
IPC: F24H9/02
Filed: 2014-03-21
Abstract: A lower cost water heater suitable for domestic and commercial application. The heater comprises an internal pressure tank (34) with a water inlet and water outlet and an insulating outer enclosing layer (22, 24, 26, 28). The outer layer portions are engaged together and locked over the tank, preferably using a tongue and groove type arrangement. The outer layer comprises a series of formed waterproof and insulating polymer sections. The portions (22, 24, 26, 28) of the outer layer may include a flattened region (48, 50) to reduce the overall width of the assembly for installation into tighter spaces. The tank comprises a long life stainless steel tank comprising few parts. The outer layer is formed of a polymer material that does not lose its insulating properties and is tough enough to not require a further external coating. The outer layer may be formed from recyclable material. The water heater uses simple designs and few parts to allow ease of manufacture, allow ease of replacement of parts and reduce the overall weight.
Patent NZ-625266-A (NZ)
Title: Improved pipe support
Inventor: LUKE BOLTON
IPC: F16L3/12
Filed: 2014-05-20
Abstract: A saddle or clip that caters for a plurality of conduit sizes is disclosed. Prior art saddles, particularly those made of polypropylene, enable only one size of pipe to be clasped. This means that the tradesperson is obliged to stock and carry varying sizes of said devices to cater for the varying diameters of pipe. This takes up more space in the tradesperson’s nail bag and may mean that the tradesperson wastes time looking for the correct size clip. The saddle or clip (a) includes at least one resilient tongue (b) that, in use, moves outward to accommodate conduits or pipes of different diameters. Embodiments with multiple tongues are also disclosed such that the clip is able to be used with a number of different sized pipes.
Patent NZ-628433-A (NZ)
Title: Chitosan-derived compositions
Inventor: RAKER JOSEPH
IPC: A61K47/36
Filed: 2013-01-17
Abstract: The present disclosure relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.
Patent NZ-628987-A (NZ)
Title: Extended recombinant polypeptides and compositions comprising same
Inventor: SCHELLENBERGER VOLKER
IPC: C07K17/00
Filed: 2010-02-03
Abstract: Disclosed is an syringe or a kit comprising a pharmaceutical compositions comprising an extended recombinant polypeptide (XTEN) comprising greater than about 36 to about 3000 amino acid residues, wherein the XTEN is characterized in that: (a) the sum of glycine (G), alanine (A), serine (S), threonine (T), glutamate (E) and proline (P) residues constitutes more than about 80% of the total amino acid sequence of the XTEN; (b) the XTEN sequence is substantially non-repetitivesuch that (i) the XTEN contains no three contiguous amino acids that are identical unless the amino acids are serine; (ii) at least about 80% of the XTEN sequence consists of non-overlapping sequence motifs, each of the sequence motifs comprising about 9 to about 14 amino acid residues consisting of four to six types of amino acids selected from glycine (G), alanine (A), serine (S), threonine (T), glutamate (E) and proline (P), wherein any two contiguous amino acid residues do not occur more than twice in each of the non-overlapping sequence motifs; or (iii) the XTEN sequence has a subsequence score of less than 10; (c) the XTEN sequence lacks a predicted T-cell epitope when analyzed by TEPITOPE algorithm, wherein the TEPITOPE algorithm prediction for epitopes within the XTEN sequence is based on a score of –9 or greater. (d) the XTEN sequence has greater than 90% random coil formation as determined by GOR algorithm; and (e) the XTEN sequence has less than 2% alpha helices and 2% beta-sheets as determined by Chou-Fasman algorithm.
Patent NZ-630002-A (NZ)
Title: Edible product and method of manufacture
Inventor: BUFTON ANDREW CHRISTOPHER
IPC: A23G3/34
Filed: 2013-05-15
Abstract: This disclosure provided an edible product having a plurality of adjacent extruded product portions comprising one or more of chocolate, baked or unbaked cereal-based composition, or cheese. The portions are connected to one another along their length by a frangible connecting portion. The disclosure also provides a method of manufacturing such a product. The method includes providing an extrusion die having a linear array of at least two interconnected openings therein; and extruding product portions through the die to produce the product. The product comprises at least one or more edible materials comprising: chocolate products, baked or unbaked cereal-based composition, or cheeses.
Patent NZ-717187-A (NZ)
Title: Drug delivery system
Inventor: BLOEMERS JOHANNES MARTINUS MARIA
IPC: A61K31/568
Filed: 2012-05-14
Abstract: The disclosure relates to a time controlled, immediate release drug delivery system for oral administration of a first active ingredient, such as a steroid, to a subject in need thereof. The disclosure additionally relates to a dual drug delivery device, comprising the time controlled, immediate release drug delivery system, further comprising a second coating comprising a second active ingredient. In one embodiment the drug delivery system is a tablet for sublingual administration of an active ingredient said tablet comprising a core, and a coating (outer coating) on the exterior surface of said core and optionally a coating that separates said outer coating from said core (separation coating), wherein said outer coating comprises a mixture of an active ingredient in amorphous form, a coating polymer and water.
Patent NZ-721667-A (NZ)
Title: Materials and methods for modulation of tendon healing
Inventor: GILCHRIST DEREK STEWART
IPC: C12N15/113
Filed: 2015-01-14
Abstract: The invention relates to the use of microRNA 29 and precursors and mimics thereof for the modulation of tendon injury and the biomechanical properties of tendon. In particular, the invention derives from the finding that synthesis of type 1 collagen in tenocytes is less sensitive to miR-29 than is synthesis of type 3 collagen, thus enabling the balance between the collagen subtypes to be modulated in favour of type 1 collagen, mitigating reduction in biomechanical properties during healing.
Patent NZ-743601-A (NZ)
Title: Inactivation of viruses by delipidation
Inventor: DIAZ LEYLA
IPC: C12N7/06
Filed: 2017-01-20
Abstract: The present invention relates to vaccines containing enveloped viruses whose envelopes have been depleted of lipids using methyl β-cyclodextrin (MBCD). Delipidation of enveloped viruses in a two-step process abolishes the infectivity of those viruses, which allows delipidated viruses to be used safely in vaccines. Use of MBCD to deplete lipids such as cholesterol, in contrast to other methods, results in viruses with less than 20% of the cholesterol of an untreated virus but such delipidated viruses retain at least 85% of the protein content of an untreated virus. Delipidation by MBCD also preserves the immunogenicity of the viral proteins. The present invention of using MBCD treatment in a two-step process to delipidate enveloped virus represents a new alternative for generation of inactivated viruses which are incorporated into effective vaccines.
Patent NZ-749201-A (NZ)
Title: Method for recovery of phosphate
Inventor: NILSEN PAAL JAHRE
IPC: C02F11/143
Filed: 2017-05-19
Abstract: The present invention provides a method for recovery of phosphate, in the form of magnesium ammonium phosphate (MAP), from a process for treating a biomass material which process comprises a digestion step performed in a digestion tank and includes a pre-treatment step employing a thermal hydrolysis, characterised in that a magnesium source is added to the material in the process flow before said flow enters the digestion tank, and phosphate is recovered as MAP as an integral part of a solid or semi-solid digestate product from the digestion tank.
Patent PT-100866-A (PT)
Inventor: DIAS FRANCISCO J
IPC: F01N13/16
Filed: 1992-09-11
Abstract: PCT No. PCT/DE92/00753 Sec. 371 Date Mar. 11, 1994 Sec. 102(e) Date Mar. 11, 1994 PCT Filed Sep. 5, 1992 PCT Pub. No. WO93/06059 PCT Pub. Date Apr. 1, 1993.A process for producing a porous fluid permeable body which is heatable by the passage of electric current therethrough. The process involves coating silicon-containing particles with a cokable organic binder to produce coated particles with a particle size fraction of 0.2 to 10 mm, forming the particles into a molding, coking the binder and heating the molding at 1400 DEG  to 2000 DEG  C. in the presence of nitrogen to form a doped body containing 30% to 100%  beta -silicon carbide.
Patent PT-101048-A (PT)
Inventor: WILLIAMS CHARLES E
IPC: E05D15/06
Filed: 1992-11-11
Abstract: A multidirectional carrier and track (10) generally comprising a disc (28,30), a track (12), and a structure (20,22) on the track defining a disc supporting surface (24,26). The disc (28,30) is supported on the disc support surface (24,26) for rotation about an axis, and has first and second ball bearing assemblies (56,58). The ball bearing assemblies have inner (64,66) and outer (68,70) races, the inner races being mounted adjacent one another along the axis. The disc also has an outer cylindrical rim portion (76), the rim portion having an inner-facing surface (77), an outer-facing surface (79) and upper and lower surfaces (82,84), the inner-facing surface (77) engaging the outer races (68,70) and the lower surface (84) contacting the track (12). The structure on the inner-facing surface (77) defines axially spaced faces projecting radially inward towards the axis in step-wise fashion, forming two axially-facing shoulders (86,88) projecting from the inner-facing surface (77). The outer paces (68,70) contact the shoulders (86,88) and are held in the outer rim portion against axial movement in one direction relative to the axis of the support member. A cylindrical reinforcing band (100) surrounds and reinforces the rim portion (76). <IMAGE>
Patent PT-110874-A (PT)
Title: Método de gestão de redes e negócio de energia elétrica
Inventor: CARLOS CHANG DOS SANTOS
IPC: G06Q50/06
Filed: 2018-07-22
Abstract: O MÉTODO É BASEADO NUM SISTEMA DISRUPTIVO COM OS ATUALMENTE EXISTENTES E QUE TERÁ COMO BASE UM GESTOR DO SISTEMA (GS) QUE RESIDIRÁ NA NUVEM, E IRÁ PROCURAR A TODO O MOMENTO O EQUILÍBRIO CONSUMO E INJEÇÃO ATRAVÉS DE UM ALGORITMO EM TEMPO REAL ATUALIZANDO O INCENTIVO PREÇO, VARIÁVEL A TODO O MOMENTO. O SISTEMA TENDERÁ PARA O EQUILÍBRIO ATRAVÉS DAS VARIÁVEIS PREÇO: PREÇO DA ENTREGA DE ENERGIA AO SISTEMA, QUE PODE SER NEGATIVO PREÇO DA ENTREGA DE DESLASTRE AO SISTEMA PREÇO DE RECEBER ENERGIA DO SISTEMA PREÇO DO USO DAS REDES
Patent PT-117478-A (PT)
Title: Painéis de parede e teto pré-fabricados com cofragem integrada
Inventor: JOÃO PEDRO DA SILVA CAMEIRA DA COSTA
IPC: B66C19/00
Filed: 2021-09-21
Abstract: A PRESENTE INVENÇÃO APRESENTA UM MÉTODO DE CONSTRUÇÃO DE PAINÉIS PRÉ-FABRICADOS DE PAREDE E TETO, INTEGRANDO COFRAGEM PERDIDA, ISOLAMENTO E ACABAMENTOS EXTERIORES E INTERIORES. OS PAINÉIS DE PAREDE PODEM SER ESTRUTURAIS (COM COFRAGEM) OU DIVISÓRIOS (SEM COFRAGEM), PODENDO SER PARA USO EXTERIOR OU INTERIOR. O ACABAMENTO DA FACE INTERIOR É EM GESSO ACARTONADO (1) E NA FACE EXTERIOR POR MATERIAL ADEQUADO PARA USO EXTERIOR (2). OS PAINÉIS SÃO ENCAIXADOS UNS NOS OUTROS POR MEIO DE UM SISTEMA MACHO/FÊMEA DA COFRAGEM PERDIDA NO CASO DOS ESTRUTURAIS OU POR CANAIS EM U NO CASO DOS DIVISÓRIOS. OS PAINÉIS DE TETO (14) SÃO FORMADOS POR UM PAINEL METÁLICO ONDULADO (6) QUE FUNCIONA COMO COFRAGEM PERDIDA PARA A LAJE DE BETÃO (9) E O POSTERIOR PISO DE REGULARIZAÇÃO (10) NA SUA FACE SUPERIOR E ACABAMENTO EM GESSO CARTONADO (1) NA SUA FACE INFERIOR.
Patent RU-94001447-A (RU)
Inventor: KELEKHSAEV B G
IPC: G06G7/16
Filed: 1994-01-14
Abstract: FIELD: instruments. SUBSTANCE: method involves inducing phase shift between signals, selection of specific time interval inside half wave period of divisor signal when two values of quotient signal f(t1) and f(t2) at t1 and t2 are measured. Moments t1 and t2 should be spaced by distance of quarter of half- period from middle of half-wave. Ratio of amplitudes of quasi-sine signals is calculated using equation. EFFECT: increased precision of measurements even when investigated signals are distorted, simplified design of corresponding device.
Patent RU-94019774-A (RU)
Inventor: MISHCHENKO JU V
IPC: G01N21/45
Filed: 1994-05-26
Abstract: FIELD: measurement technology. SUBSTANCE: use of method provides for performance of interference modulation with allocation of one measurement interval, formation of one interference picture with its conversion into one sequence of electric pulses, registration of fronts in this sequence, determination of three time intervals within each modulation period and registration of changes of interference order at end of last modulation period by results of registration of fronts and determination of them intervals. In addition there is formed second interference picture shifted through quarter period of interference with reference to first one. It is then converted into second sequence of electric pulses. Fronts in first sequence are registered with allowance for presence of pulses in second sequence. Second measurement interval is allocated within each modulation period. Four time intervals are determined for each measurement interval. resulting change f interference order is calculated with allowance for number of registered fronts and determined time intervals. EFFECT: increased authenticity and precision while registering changes of order of interference under conditions of use of single-channel interference devices.
Patent RU-94021980-A (RU)
Inventor: TARANOV G I
IPC: F25B15/00
Filed: 1994-06-09
Abstract: FIELD: refrigerating engineering. SUBSTANCE: thermoelectric battery unit consists of several sections whose cold and hot junctions are provided with heat exchange devices connected in series and used for circulation of mixture of liquids. Heat exchange intensifying devices are made in the form of two interconnected circulating loops partially filled with liquid. Components circulating in these loops absorb heat during mixing; liquid propane and acetone being used for this purpose. Liquid mixer of both circulating loops is connected with heat-insulated chamber. Above-mentioned features enhance power efficiency of refrigerator due to use of heat released from hot junctions for additional generation of cold and due to effective modes of operation ensured structurally at simultaneous rise of temperature of heat released to surrounding medium and drop of temperature of cold being generated. EFFECT: enhanced efficiency.