baber/WOPTO huggingface dataset:
Patent CA-3132298-A1 (CA)
Inventor: ECKELMAN BRENDAN P
IPC: C07K19/00
Filed: 2012-06-28
Abstract: This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and second polypeptide comprising of at least one the following: an Fc polypeptide or an amino acid sequence that is derived from an Fc polypeptide; a cytokine targeting polypeptide or a sequence derived from a cytokine targeting polypeptide; a WAP domain containing polypeptide or a sequence derived from a WAP containing polypeptide; and an albumin polypeptide or an amino acid sequence that is derived from a serum albumin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.
Patent CA-3132747-A1 (CA)
Title: Binding secure keys of secure guests to a hardware security module
Inventor: BUENDGEN REINHARD
IPC: G06F21/44
Filed: 2020-02-27
Abstract: A method, computer program product, and a system where a secure interface control configures a hardware security module for exclusive use by a secure guest. The secure interface control ("SC") obtains a configuration request (via a hypervisor) to configure the hardware security module (HSM), from a given guest of guests managed by the hypervisor. The SC determines if the HSM is already configured to a specific guest of the one or more guests, but based on determining that the HSM is not configured to the and is a secure guest the SC forecloses establishing a configuration of the HSM by limiting accesses by guests to the HSM exclusively to the given guest. The SC logs the given guest into the HSM by utilizing a secret of the given guest. The SC obtains, from the HSM, a session code and retains the session code.
Patent CA-3134991-A1 (CA)
Title: Pharmaceutical composition for treating cancer comprising microrna as active ingredient
Inventor: LEE TAEWOO
IPC: A61P35/00
Filed: 2016-02-25
Abstract: The present invention relates to a pharmaceutical composition for treating cancer comprising, as an active ingredient, at least one miRNA selected from a group consisting of miR-3670, miR-4477a and miR-8078. The pharmaceutical composition for treating cancer according to the present invention has superior effects of suppressing proliferation of cancer cells and inducing destruction of cancer cells. Accordingly, the pharmaceutical composition of the present invention may be effectively used as an anticancer agent.
Patent CA-3135605-A1 (CA)
Inventor: BEAUPRE DENIS
IPC: G01G19/08
Filed: 2020-03-31
Abstract: There is described a method for confirming delivery of bulk material from a bed of a dump truck based on hydraulic pressure. The dump truck has a driving device moving the bed between a rest position and a delivery position. The method generally having: using a hydraulic pressure sensor, measuring a plurality of hydraulic pressure values indicative of pressure of a hydraulic fluid of the driving device as the bed is moved; and using a controller communicatively coupled to the hydraulic pressure sensor: monitoring a slope at which at least some of the plurality of hydraulic pressure values vary over a given period of time; and generating a delivery confirmation indicative that a delivery of the bulk material has occurred based on a comparison between said monitored slope and a delivery slope threshold.
Patent CA-3136740-A1 (CA)
Inventor: SENNINO BARBARA
IPC: C07K14/73
Filed: 2020-04-30
Abstract: L'invention concerne des compositions et des méthodes pour le traitement du cancer utilisant une thérapie cellulaire à base de néo-TCR avec une construction d'expression CD8. Dans certains modes de réalisation, la présente invention concerne une cellule, comprenant un récepteur du lymphocyte T (TCR) exogène et un CD8 exogène. Dans certains modes de réalisation, le CD8 exogène comprend au moins un monomère. Dans certains modes de réalisation, ledit au moins un monomère du CD8 exogène comprend un domaine extracellulaire, un domaine transmembranaire, un domaine intracellulaire, des fragments de ceux-ci ou des combinaisons de ceux-ci.
Patent CA-3136755-A1 (CA)
Inventor: MCLAUGHLIN DAVID
IPC: G16H20/10
Filed: 2020-05-07
Abstract: La présente invention concerne une méthode consistant à déterminer l'administration d'un dosage à partir d'un inhalateur apte à administrer un principe actif (API) en tant qu'aérosol inhalable à un utilisateur, comprenant au moins les étapes consistant (i) à mesurer un flux d'air d'inhalation par un utilisateur pendant une occasion d'utilisation de l'inhalateur pour déterminer la partie de l'inhalation située au-dessus d'un seuil de vitesse aérodynamique F1 ; (ii) à mesurer le volume d'air inhalé par l'utilisateur pendant l'occasion d'utilisation de l'inhalateur pour déterminer la partie d'inhalation se produisant avant un seuil de volume balayé V1 ; (iii) à déterminer une première partie P1 du dosage fourni par l'inhalateur pendant l'occasion d'utilisation située au-dessus du seuil F1 et fournie avant le seuil V1.
Patent CA-3138477-A1 (CA)
Title: Method and device for eliminating offset of fluxgate magnetometer
Inventor: YUAN KAIXIN
IPC: G01R33/04
Filed: 2021-11-10
Abstract: An offset data acquisition method and device of a fluxgate magnetometer are provided by the present disclosure, wherein the offset data acquisition method of the fluxgate magnetometer comprises: controlling the first analog switch, the second analog switch and the third analog switch to change directions within a preset period to obtain eight switch direction combinations between the first analog switch, the second analog switch and the third analog switch; acquiring magnetic field measurement data corresponding to an each of the switch direction combinations; and the magnetic field measurement data comprises x-axis magnetic field measurement data, y-axis magnetic field measurement data and z-axis magnetic field measurement data; and acquiring the offset data based on influence factors of an offset and the magnetic field measurement data within the preset period.
Patent CA-3140863-A1 (CA)
Inventor: PIVOVAR ROSS EVAN
IPC: G21C7/36
Filed: 2020-06-09
Abstract: A method designs nuclear reactors using design variables and metric variables. A user specifies ranges for the design variables and threshold values for the metric variables and selects design parameter samples. For each sample, the method runs three processes, which compute metric variables for thermal-hydraulics, neutronics, and stress. The method applies a cost function to compute an aggregate residual of the metric variables compared to the threshold values. The method deploys optimization methods, either training a machine learning model using the samples and computed aggregate residuals, or using genetic algorithms, simulated annealing, or differential evolution. When using Bayesian optimization, the method shrinks the range for each design variable according to correlation between the respective design variable and estimated residuals using the machine learning model. These steps are repeated until a sample having a smallest residual is unchanged for multiple iterations. The final model assesses relative importance of each design variable.
Patent CA-3141398-A1 (CA)
Title: Methods and systems for measuring pore volume compressibility with low field nuclear magnetic resonance techniques
Inventor: ALSINAN MARWAH MUFID
IPC: G01N24/08
Filed: 2020-05-19
Abstract: Systems, methods, and apparatuses for determining pore volume and pore volume compressibility of secondary porosity in rock samples is disclosed. In some implementations, determining a pore volume of a secondary porosity in a rock core sample may include saturating the rock sample with deuterium oxide (D2O) by applying a vacuum to the core sample covered by D2O; centrifuging the saturated rock sample at a selected rotational speed in the presence of a second fluid to displace a portion of the D2O from the rock sample with the second fluid; measuring the rock sample with low-field 1H nuclear magnetic resonance (NMR) to determine a volume of the second fluid within the rock sample; and determining a pore volume associated with a secondary porosity based on the volume of the second fluid within the rock sample.
Patent CA-3143837-A1 (CA)
Inventor: STOEVA VIKTORIYA
IPC: G06V20/50
Filed: 2021-12-23
Abstract: Techniques are described for automated operations related to analyzing visual data from images captured in rooms of a building and optionally additional captured data about the rooms to assess room layout and other usability information for the building's rooms and optionally for the overall building, and to subsequently using the assessed usability information in one or more further automated manners, such as to improve navigation of the building. The automated operations may include identifying one or more objects in each of the rooms to assess, evaluating one or more target attributes of each object, assessing usability of each object using its target attributes' evaluations and each room using its objects' assessment and other room information with respect to an indicated purpose, and combining the assessments of multiple rooms in a building and other building information to assess usability of the building with respect to its indicated purpose.
Patent CA-3144516-A1 (CA)
Inventor: DELAHAYE THOMAS NOLWENN EMMANUEL
IPC: F01D25/24
Filed: 2020-07-10
Abstract: Disclosed is a compressor (1) of a dual-flow aircraft turboshaft engine extending longitudinally along an axis X, the compressor (1) comprising a low-pressure compressor, a high-pressure compressor (3) and an intermediate casing (2) axially connecting the low-pressure compressor and the high-pressure compressor (3), the high-pressure compressor (3) comprising an inlet guide stator (33) comprising a retaining ring (34), an outer high-pressure compressor casing (35) and a plurality of vanes (38), the compressor (1) comprising an immobilising device (5) comprising at least one first member secured to the intermediate casing (2) and at least one second member secured to the retaining ring (34) and configured to cooperate with the first member in order to prevent tangential movement while allowing axial movement and radial movement of the retaining ring (34) relative to the intermediate casing (2) according to the axis X.
Patent CA-3145464-A1 (CA)
Title: System and method for determining residue coverage within a field following a harvesting operation
Inventor: FERRARI LUCA
IPC: A01B79/00
Filed: 2020-07-29
Abstract: A method for determining residue coverage within a field after a harvesting operation may include receiving yield data associated with an estimated crop yield across a field and generating an estimated residue coverage map for the field based at least in part on the yield data. The method may further include receiving residue data associated with residue coverage across a surface of the field following the performance of a harvesting operation within the field. Additionally, the method may include generating an updated residue coverage map for the field based at least in part on the estimated residue coverage map and the residue data.
Patent CA-3145904-A1 (CA)
Title: Compositions comprising bacterial strains
Inventor: MULDER Imke Elisabeth
IPC: A61K35/742
Filed: 2020-07-03
Abstract: The invention provides pharmaceutical compositions comprising bacteria and the use of such compositions in the treatment of disease.
Patent CA-3149623-A1 (CA)
Title: Motorised chair
Inventor: KACHIRSKI BILL
IPC: A47C1/02
Filed: 2019-10-18
Abstract: A chair comprising a sub-frame in contact with the ground and connected to the chair the sub-frame including four wheels to support the chair on the ground and a set of powered driving wheels connected to the rear of the sub-frame to allow the chair to be propelled.
Patent CA-3149779-A1 (CA)
Inventor: SHOESMITH WILLIAM
IPC: H04N21/658
Filed: 2020-08-19
Abstract: A playback device includes programming for connecting to a first wireless local area network (WLAN) and storing a first set of network configuration parameters including an identifier of the first WLAN and a first security parameter for the first WLAN. The functions also include disconnecting from the first WLAN, receiving a second set of network configuration parameters including an identifier of a second WLAN and a second security parameter for the second WLAN, and storing the second set of network configuration parameters. The functions also include reconnecting to the first WLAN using the stored first set of network configuration parameters and, after reconnecting to the first WLAN, transmitting, absent user request, the second set of network configuration parameters to at least one other playback device that is connected to the first WLAN for storage on the at least one other playback device that is connected to the first WLAN.
Patent CA-3151140-A1 (CA)
Title: Systemes et procedes pour systeme d'intelligence artificielle
Inventor: FRIST ROBERT JR
IPC: G06F40/40
Filed: 2020-10-28
Abstract: L'invention concerne un procédé 1200 qui peut comprendre la génération 1202, dans un système de traitement de langage naturel (NLP), d'une pluralité d'objets de données d'entité 112. Le procédé 1200 peut comprendre la génération 1204, dans le système NLP, d'une pluralité d'objets de données d'activité 114. Le procédé 1200 peut comprendre la génération 1206, sur au moins un serveur 104, d'un objet de données d'évaluation 106. L'objet de données d'évaluation 106 peut comprendre un objet de données de problème 700, un objet de données d'observation 800, ou un objet de données d'action 900. Le procédé 1200 peut comprendre la configuration 1208 de chaque objet de données de problème 700, objet de données d'observation 800 ou objet de données d'action 900 d'un objet de données d'évaluation 106 avec une rubrique de notation. L'invention invention concerne également d'autres procédés, systèmes et supports lisibles par ordinateur.
Patent CA-3152527-A1 (CA)
Inventor: LARKINS TODD CHANDLER
IPC: A01F25/12
Filed: 2022-03-17
Abstract: A bracket for use in a vegetation hanging and drying system includes a mounting plate configured to couple to a vertical support shaft of the vegetation hanging and drying system, and a racking plate extending from the mounting plate and configured to receive a horizontal bar of the vegetation hanging and drying system.
Patent CA-3153727-A1 (CA)
Inventor: SINHA DEBASISH
IPC: A61P27/02
Filed: 2020-09-10
Abstract: A method of inhibiting neutrophil activation in retinal pigment epithelial (RPE) cells comprising administering an inhibitor of interferon (IFN) ? to a subject in need thereof, as well as a method of restoring lysosomal function of RPE cells comprising administering a polypeptide comprising ßA1-crystallin or a nucleic acid encoding the polypeptide to a subject in need thereof, are provided. A method of rejuvenating Vacuolar-type H+-ATPase (V-ATPase) activity in RPE cells by modulating assembly and disassembly of the V-ATPase in a subject in need thereof also is provided. Additionally, a method of treating diabetic retinopathy in a subject comprising administering a polypeptide comprising ßA1-crystallin or a nucleic acid encoding the polypeptide to the subject is provided.
Patent CA-3156257-A1 (CA)
Title: Transdermal delivery of dronabinol
Inventor: PLAKOGIANNIS FOTIOS M
IPC: A61K9/70
Filed: 2020-10-02
Abstract: Provided is a transdermal drug delivery system comprising dronabinol. The dronabinol transdermal delivery system provides a drug plasma concentration at predetermined rate for a predetermined period of time, offering a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of nausea and/or vomiting associated with, for example, chemotherapy.
Patent CA-3157686-A1 (CA)
Inventor: BHATTACHARJEE ARINDAM
IPC: C07K7/08
Filed: 2020-10-12
Abstract: Disclosed are agents and methods of using the agents to treat or prevent pain and/or induce anesthesia. The agents may be peptides, siRNAs, and/or shRNAs that target adaptin protein 2-clathrin mediated endocytosis (AP2-CME). Peptides of the present disclosure may contain the following sequence X1X2X3X4LX5 (SEQ ID NO:7), where X1 is D, E, S, or T, where the D, E, S, and/or the T is optionally phosphorylated, X2, X3, and X3 are independently chosen from any amino acid.
Patent CA-3159082-A1 (CA)
Inventor: HUTTERER NICOLE
IPC: B29C45/00
Filed: 2022-05-17
Abstract: The present disclosure describes a transport tray that includes a plurality of sleeves that are each configured to receive a substantially cylindrical container having a cylindrical container wall and a container bottom surface arranged orthogonally to the container wall. Each sleeve includes a top opening, a bottom opening, a sleeve wall that extends along a sleeve axis between the top opening and the bottom opening and is configured to abut at least a portion of the container wall of a respective container, and one or more support feet that are adjacent to the bottom opening and extend from the sleeve wall towards the sleeve axis, wherein each support foot comprises a bottom surface and a top surface configured to abut the container bottom surface of a respective container, such that a gap is formed between the support foot bottom surface and the container bottom surface along the sleeve axis. The one or more support feet comprise a thermally conductive polymer.
Patent CA-3161902-A1 (CA)
Title: Methods and systems for precision dosing of fluid systems
Inventor: HANEY VIRGIL
IPC: E21B43/12
Filed: 2022-06-08
Abstract: A method and system to precision dose a fluid system with an injection fluid having chemicals is provided. The method and system includes providing a buffered dosing tank of a known geometry between a source tank and an injection pump. The fluid level detector measures the pressure of the dosing tank to determine a fluid level. The fluid level together with the known geometry allow for a controller to calculate a fluid volume in the dosing tank and a change of volume over time. Using the change of volume over time, the controller can calculate an actual dose rate and adjust a speed or duty cycle of the injection pump such that the actual dose rate is approximately the target dose rate.
Patent CA-3165165-A1 (CA)
Inventor: BOGOROCH MATTHEW
IPC: G06Q10/04
Filed: 2022-06-23
Abstract: Art example server for resource allocation optimization amongst a plurality of allocation targets includes: a memory and a communications interface; and a processor interconnected to the memory and the communications interface, the processor configured to: obtain a revenue model associated with an account, the revenue model trained based on a historical resource allocation and revenue for the account;  extract, from the revenue model, coefficients corresponding to each of the allocation targets;  define, using the extracted coefficients, a symbolic representation of the revenue model;  define target constraints for each of the allocation targets based on resource allocation constraints, the target constraints expressed as symbolic representations;  apply Lagrangian optimization to the symbolic representation of the revenue model and the target constraints to obtain a set of stationary points; evaluate each of the stationary points from the set to select a stationary point optimizing the revenue model, the selected stationary point defining a resource allocation for each of the allocation targets; and allocate, for each of the allocation targets, resources according to the resource allocation defined by the stationary point.
Patent CA-3166302-A1 (CA)
Inventor: FEENEY CONNOR
IPC: A61M39/08
Filed: 2021-01-20
Abstract: A drainage tubing management device is provided. The drainage tubing management device generally comprises a body including a planar field, and having plural pairs of spaced-apart protrusions extending from said field, each pair of protrusions sized to accept flexible drainage tubing therebetween, wherein pairs of the protrusions are arranged in at least first and second rows such that drainage tubing may be retained with respect to said body along the first and second rows, at least one aperture in said body, and a securement mechanism comprising one or more of (a) a post having a longitudinal axis, said post being insertable through within said aperture and having a terminal flange occluding passage of said post through said aperture, said post being sufficiently rigid to support said body and (b) a flexible hanging strap insertable through said aperture and having a terminal flange occluding passage of said strap through said aperture.
Patent CA-3166958-A1 (CA)
Inventor: RAO ARCHANA NAGARAJA
IPC: A61M39/24
Filed: 2021-02-04
Abstract: L'invention concerne un connecteur sans aiguille comportant un orifice d'accès et un revêtement antimicrobien à libération prolongée uniquement sur une surface supérieure de l'orifice d'accès. La surface supérieure de l'orifice d'accès peut être définie par une surface supérieure d'une extrémité proximale d'un boîtier et une surface supérieure d'une partie de tête d'une soupape compressible disposée à l'intérieur d'une cavité interne du boîtier. Dans certains modes de réalisation de la présente invention, le revêtement antimicrobien à libération prolongée est disposé sur : (i) la surface supérieure de l'extrémité proximale du boîtier, ou (ii) la surface supérieure de la partie de tête de la soupape compressible, ou (iii) le revêtement antimicrobien à libération prolongée est uniquement à la fois sur la surface supérieure, l'extrémité proximale du boîtier et la surface supérieure de la partie tête de la soupape compressible.
Patent CA-3170390-A1 (CA)
Inventor: BERECIARTUA-PEREZ ARANZAZU
IPC: G06T7/00
Filed: 2021-03-05
Abstract: Dans la réalisation d'un procédé mis en ?uvre par ordinateur permettant de quantifier des dommages biotiques sur des feuilles de plantes cultivées, l'ordinateur reçoit une image de plante (410) montrant une plante cultivée, montrant la partie aérienne de la plante, avec des tiges, des branches et des feuilles et montrant le sol sur lequel la plante est placée. Un module de segmentation obtient une image de plante segmentée qui est un ensemble contigu de pixels qui montre un contour (460A) de la partie aérienne, le contour (460A) ayant une région de marge (458) qui montre partiellement le sol. L'ordinateur utilise un réseau neuronal convolutif qui traite l'image de plante segmentée par régression pour obtenir un degré de dommages, le réseau neuronal convolutif ayant été formé par traitement d'images de plante segmentées annotées par dommages.
Patent CA-3171001-A1 (CA)
Title: Amorphous calcium carbonate for treatment of acidosis
Inventor: BEN YOSSI
IPC: A61P31/12
Filed: 2021-01-28
Abstract: The preset invention is directed to ACC particles stabilized by at least one stabilizing agent, a pharmaceutical composition including same, and methods of using same, such as for treating or preventing an acidosis-related disease or condition in a subject in need thereof.
Patent CA-3171267-A1 (CA)
Inventor: SHEARER TODD WEBSTER
IPC: A61P25/28
Filed: 2021-03-12
Abstract: The present disclosure provides methods of treating cancer or light chain amyloidosis in a subject in need thereof comprising administering a combination therapy comprising an effective amount of Form A of nirogacestat dihydrobromide and a B-cell maturation antigen (BCMA)-directed therapy to the subject and the uses thereof.