baber/WOPTO huggingface dataset:
Patent CA-2835868-C (CA)
Inventor: MASERE JONATHAN
IPC: C07C49/657
Filed: 2012-06-11
Granted: 2018-03-13
Abstract: The invention provides a method for synthesizing 7-Acetyleno quinone methide compounds that is safe and inexpensive. The meod avoids the need for extremely cold reaction temperatures and unlike the prior art does not require any highly explosive materials. The method comprises the steps of: a) performing a condensation reaction between 3,5-di-tert-butyl-4-hydroxybenzaledhyde and a secondary amine thereby forming a secondary amine quinone methide intermediate; b) removing water from the secondary amine quinone methide intermediate by azetropic distillation; c) adding the dehydrated secondary amine quinone methide intermediate to an organic medium containing a metal acetylide to form a Mannich bas intermediate; and d) adding a release agent to the Mannich base intermediate to yield a 7-Acetyleno quinone methide
Patent CA-2838237-C (CA)
Title: Dermal filler compositions including antioxidants
Inventor: LIU FUTIAN
IPC: A61K8/67
Filed: 2012-06-01
Granted: 2020-05-26
Abstract: Provided are injectable dermal fillers comprising crosslinked hyaluronic that further comprise one or more vitamin C derivatives, covalently conjugated thereto. Also provided are methods of making such injectable dermal fillers.
Patent CA-2840460-C (CA)
Inventor: ATTINGER ANTOINE
IPC: C07K16/46
Filed: 2012-07-09
Granted: 2022-08-16
Abstract: The present invention relates to antagonist antibodies or fragments thereof that bind to human 0X40. In an aspect, the present invention relates to an antagonist antibody or fragment thereof that binds to human 0X40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and a heavy chain CDR3 cornprising the amino acid sequence of SEQ ID NO: 3; and comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 4, a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 5, and a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6.
Patent CA-2843016-C (CA)
Title: Methods and apparati for nondestructive detection of undissolved particles in a fluid
Inventor: MILNE GRAHAM F
IPC: G01N15/14
Filed: 2012-08-29
Granted: 2019-09-17
Abstract: The apparati, methods, and computer program products disclosed herein can be used to nondestructively detect undissolved particles, such as glass flakes and/or protein aggregates, in a fluid in a vessel, such as, but not limited to, a fluid that contains a drug.
Patent CA-2845371-C (CA)
Title: Skate with injected boot form
Inventor: LEFEBVRE ANDRE MARC
IPC: A63C1/38
Filed: 2014-03-11
Granted: 2022-06-21
Abstract: A boot form for a hockey skate is made of multiple plastic materials having different hardness properties, or different flexural moduli, and is formed via an injection-molding process or another similar process. One or more of the plastic materials may be reinforced with fibers of glass, carbon, aramid, or another stiffening material to strengthen one or more regions of the boot form. For example, pellets of a first plastic material having a flexural modulus of approximately 190 MPa (e.g., a polyamide elastomer block amide) may be injected into a mold to form a softer upper region of the boot form. And pellets of a second plastic having a flexural modulus of approximately 20,000 MPa (e.g., a Nylon 12 with long glass fibers) may be injected into the mold to form a stiffer lower region of the boot form. Additional skate components may then be attached to the boot form.
Patent CA-2851665-C (CA)
Title: Dispositif pour preparer une matiere plastique
Inventor: FEICHTINGER KLAUS
IPC: B02C18/08
Filed: 2012-10-12
Granted: 2017-11-07
Abstract: L'invention concerne un dispositif de pré-traitement et de transport ou malaxage consécutif de plastiques, comportant une cuve (1) présentant un outil de mélange et/ou de broyage (3) tournant autour d'un axe de rotation (10). Une paroi latérale (9) présente une ouverture (8) à travers laquelle le matériau plastique peut être distribué, le dispositif comportant également un transporteur (5) présentant une vis (6) tournant dans un boîtier (16). L'invention est caractérisée en ce que le prolongement imaginaire de l'axe longitudinal (15) du transporteur (5), dans le sens opposé au sens de transport (17), s'étend à côté de l'axe de rotation (10), l'axe longitudinal (15) étant décalé côté écoulement, de l'ordre d'un écart (18), par rapport à la radiale (11) parallèle à l'axe longitudinal (15), le rapport L/D de la vis (6) est = 7 et l'effet de compression de la vis (6) n'intervient qu'à partir d'un écart (A) supérieur à 1,5 fois le diamètre (d) de la vis (6).
Patent CA-2852376-C (CA)
Inventor: MATHON RICHARD
IPC: B29C70/54
Filed: 2012-10-17
Granted: 2020-04-07
Abstract: The invention relates to an impregnation mandrel (100) for the production of gas turbine casings made from composite material, said mandrel comprising: an annular wall (102), in which the profile of the outer surface corresponds to that of the internal surface of the casing to be produced; two side plates (104), the profiles of which correspond to those of external casing flanges to be produced; and a removable device (106) for clamping a layer having a fibrous texture, which is wound around the mandrel.
Patent CA-2855352-C (CA)
Inventor: ARNONE MILES
IPC: G06Q50/34
Filed: 2012-11-12
Granted: 2016-12-20
Abstract: Systems and methods in accordance with embodiments operate an anti- cheating hybrid game. One embodiment includes an anti-cheating hybrid game constructed to communicate occurrences based upon a player's skillful execution of an entertainment game that triggers a randomly generated payout to a gambling game; where the anti-cheating hybrid game incorporates an anti-cheating module constructed to: receive player data for a player, where the player data is indicative of the player's current gameplay performance at the entertainment game; analyze the player data to determine whether cheating is occurring by comparing the player's current gameplay performance with historical gameplay data to evaluate whether the player's current gameplay performance is beyond the statistical limits of the randomness inherent in the anti-cheating hybrid game; and send a command to penalize the player during play of the entertainment game based upon a determination that cheating has occurred from the analyzed player data.
Patent CA-2862341-C (CA)
Inventor: LI JIA
IPC: A61B17/3205
Filed: 2013-01-24
Granted: 2021-01-12
Abstract: A system for creating a patient-specific instrument model for chondral graft plugging comprises a bone model generator for producing a bone/cartilage model of an articular region of a bone from images thereof. A defect geometry identifier identifies a graft geometry from a defect region of said bone/cartilage model. A donor locator locates an autograft at a donor site or identifies an allograft from a database, using said bone/cartilage model and the graft geometry. A patient-specific instrument model generator creates a model of a graft-plugging patient-specific instrument from said bone/cartilage model, and the graft geometry, the graft-plugging patient-specific instrument model comprising a bone/cartilage interface surface shaped as a function of the bone/cartilage model for the at least one graft-plugging patient-specific instrument to be selectively positioned on the bone/cartilage to pose the autograft or the allograft at the defect region.
Patent CA-2863695-C (CA)
Title: Virus like particle composition
Inventor: UENO RYUJI
IPC: C07K14/525
Filed: 2013-02-15
Granted: 2023-01-17
Abstract: Disclosed is a particle comprising a polypeptide and at least one antigen, and a composition comprising the same, as well as a use of the peptide and composition for various vaccine and pharmaceutical compositions for treatment of diseases such as immune diseases and cancer.
Patent CA-2866808-C (CA)
Title: Isocyanate-based prepolymer
Inventor: VERBEKE WESLEY
IPC: C08G18/18
Filed: 2013-03-19
Granted: 2019-10-15
Abstract: The invention relates to an isocyanate-containing prepolymer obtainable by reacting at least one isocyanate with at least one first compound selected from the group comprising monohydric alcohols, thiols and secondary amines; wherein the ratio of the NCO value of the isocyanate-containing prepolymer, to the OH, SH or NH value, of said monohydric alcohol, thiol or secondary amine respectively ranges from 0.0005 to 1.0000 and wherein said at least one first compound is present in a total amount of at least 40% by weight based on the total weight of the isocyanate-containing prepolymer. The prepolymer can be used to make a wide variety of polyurethane products.
Patent CA-2870392-C (CA)
Inventor: BEN MUVHAR SHMUEL
IPC: A61M29/02
Filed: 2002-10-03
Granted: 2017-11-14
Abstract: A flow reducing implant which includes a body having a selectively narrowing diameter and a cross sectional dimension having a narrowed segment. The narrowed segment includes a plurality of engagement points configured to be engaged by a plurality of engagement elements of a delivery catheter.
Patent CA-2872612-C (CA)
Title: Procede et systeme pour abandonner un trou de forage
Inventor: CONNELL PAUL L
IPC: E21B25/10
Filed: 2012-06-01
Granted: 2017-03-21
Abstract: L'invention porte sur un procédé d'abandon de trou de forage, lequel procédé consiste en le déplacement d'un outil dans le trou de forage, la coupe d'une enveloppe avec une première partie de l'outil, l'alésage du trou de forage dans une zone où l'enveloppe a été coupée avec une seconde partie de l'outil, la déconnexion d'un train de tiges de forage à partir de l'outil, et le cimentage du trou de forage par l'intermédiaire du train de tiges de forage.
Patent CA-2879013-C (CA)
Inventor: HANSEN NICHOLAS
IPC: A47J31/46
Filed: 2013-07-18
Granted: 2017-08-15
Abstract: A beverage preparation machine configured to dispense a beverage through an outlet nozzle assembly, the machine comprising: an outlet nozzle assembly having provided therethrough a first outlet and a second outlet; and one or more conduits arranged to deliver selectably fluid to the first outlet or the second outlet.
Patent CA-2882328-C (CA)
Title: Body panel for a transport vehicle including a heat-exchange device and transport vehicle including such a body panel
Inventor: PELISSIER BERTRAND
IPC: B64C1/12
Filed: 2013-09-19
Granted: 2019-07-23
Abstract: The invention relates to a body panel (1) for a transport vehicle in particular for an aircraft including a supporting plate (2) and a heat-exchange device (6), said supporting plate forming (2) on the outer surface (4) thereof facing the exchanger (6) an indentation (10) extending in the body of the supporting plate (2) holding the heat-exchange device (6) such that the heat-exchange device (6) does not extend beyond the general profile of the body of the transport vehicle.
Patent CA-2883704-C (CA)
Title: Methods for treatment or prevention of damage resulting from radiation, trauma or shock
Inventor: BAKER SHENDA M
IPC: A61P29/00
Filed: 2013-09-20
Granted: 2021-09-28
Abstract: Described herein are methods of treating a subject that has been or will be exposed to radiation, trauma or shock, the method comprising identifying a subject that has been or will be exposed to radiation, and treating the subject with a compound that treats, reduces the severity or delays the onset of sepsis or reduces the likelihood of mortality in a subject upon administration of a therapeutically effective amount the compound to the subject.
Patent CA-2884514-C (CA)
Inventor: BRINKWORTH LOUISE A
IPC: A01N25/32
Filed: 2013-09-27
Granted: 2021-03-09
Abstract: La présente invention concerne des compositions herbicides comprenant une quantité efficace synergiquement herbicide (a) d'aminocyclopyrachlore ou d'un sel ou ester, acceptables sur le plan agricole, correspondants et (b) d'aminopyralide ou d'un sel ou ester, acceptables sur le plan agricole, correspondants. La présente invention concerne également des procédés de lutte contre une végétation non souhaitée, qui comprennent l'application sur la végétation ou sur une zone à proximité de la végétation, ou l'application sur le sol ou dans l'eau, en vue d'empêcher l'émergence ou la croissance de végétation, (a) d'aminocyclopyrachlore ou d'un sel ou ester, acceptables sur le plan agricole, correspondants et (b) d'aminopyralide ou d'un sel ou ester, acceptables sur le plan agricole, correspondants, (a) et (b) étant chacun ajoutés en une quantité suffisante pour produire un effet herbicide synergique.
Patent CA-2884517-C (CA)
Inventor: KLIPSTEIN DONALD L
IPC: F21V5/04
Filed: 2007-12-21
Granted: 2017-01-24
Abstract: An LED work light, which includes: a handle section, a head section, a plurality of LEDs mounted in the head section; and means for the plurality of LEDs to receive electrical power, wherein each LED within the plurality of LEDs is associated with a lens that is located forward of its associated LED, and a diffuser is located forward of each LED and close to each LED, so that each LED produces an illuminated spot on the diffuser, the lens associated with each LED in the plurality of LEDs foBENrms a beam by projecting an image of the illuminated spot on the diffuser, wherein all of the said lenses associated with the LEDs in the plurality of LEDs form beams that merge together to form a useful combined beam.
Patent CA-2887383-C (CA)
Inventor: CUNNINGHAM BRIAN
IPC: A61L2/18
Filed: 2013-10-11
Granted: 2022-06-14
Abstract: L'invention concerne un dispositif de nettoyage de poignées de porte et de plaques de propreté de porte comprenant un logement (60) à installer sur une porte, le logement comportant un réservoir (76) de liquide désinfectant et une tête de pulvérisation (71), un bras d'actionnement (72) qui fait saillie vers l'extérieur à partir du logement et est fonctionnellement associé, lors de l'utilisation, avec un encadrement de porte dans lequel est montée la porte, de telle sorte que l'ouverture ou la fermeture de la porte entraîne un mouvement du bras d'actionnement (72) de façon à faire fonctionner la tête de pulvérisation et à pulvériser un liquide désinfectant sur la poignée de porte, plaque de propreté de porte ou autre surface de porte, le bras d'actionnement coopérant avec l'encadrement de porte pour faire fonctionner la tête de pulvérisation.
Patent CA-2892409-C (CA)
Inventor: LIU SUHUA
IPC: E21C31/10
Filed: 2013-11-26
Granted: 2021-07-20
Abstract: La présente invention concerne une excavatrice ou chargeuse comportant des sections de course de roulement extensibles et escamotables disposées en parallèle, comprenant un bras oscillant (1), un corps de machine (2), une tête de travail (9); le bras oscillant (1) comporte un rouleau avant (3), un rouleau arrière (4), un chemin de roulement avant (5), un chemin de roulement arrière (6), un bras télescopique (2), un bras de support télescopique (8) et analogues; le chemin de roulement avant (3) et le chemin de roulement arrière (6) sont disposés en parallèle; le rouleau avant (3) roule dans le chemin de roulement avant (5), et le rouleau arrière (4) roule dans le chemin de roulement arrière (6); le rouleau avant (5) et le rouleau arrière (6) sont en coordination grâce à un frottement par roulement pour assurer le support du bras télescopique (7) pour son extension et son escamotage sous l'effet du frottement par roulement sur le bras de support télescopique (8); la tête de travail (9) est connectée au bras télescopique (7); le bras télescopique (7) commande l'extension et l'escamotage de la tête de travail (9); et le bras de support télescopique (8) est connecté au corps de machine (2). L'invention concerne également un procédé pour la disposition en parallèle de sections de course de roulement extensibles et escamotables par frottement.
Patent CA-2896522-C (CA)
Inventor: IVAN ERIC J SR
IPC: F25C5/04
Filed: 2015-07-09
Granted: 2017-02-14
Abstract: An ice auger has a rotatable rod adjacent and parallel to the central shaft supported at the bottom in a cylindrical receptacle. A vertical ice reaming blade is attached to the rod above the receptacle and a retaining loop affixed to the shaft and positioned above the blade prevents the rod from rising out of the receptacle. A right angled handle at the top of the rod extends outward above and in the same plane as the blade. A spring biased latch assembly disposed near the top of the shaft engages the handle with the blade in rest position. Releasing the latch frees the rod to rotate 180° and move the blade to use position extending outward beyond the standard auger members to ream the bottom of the ice hole. Vertical support posts stabilize the system and prevent wobble. One post functions as a stop and back support for the blade during use.
Patent CA-2900665-C (CA)
Inventor: JOHNSON MARTIN REID
IPC: C07C303/24
Filed: 2014-02-11
Granted: 2021-02-09
Abstract: The present invention is directed to methods for preparing a fluorosulfonate ester or a salt thereof, through a reaction of a dissolved sulfonyl fluoride (RFSO2F) with alkoxide anion (RO- ) optionally in the presence of an aprotic base (B), where RF is fluorine or a C1-C8 perfluoroalkyl group, and R is a primary alkyl or alkoxyalkyl. Alkoxide anion (RO-) can be generated from a precursor such as an alcohol or silyl ester.
Patent CA-2901941-C (CA)
Inventor: HOWARD PHILIP WILSON
IPC: A61P35/00
Filed: 2014-03-13
Granted: 2020-04-07
Abstract: Disclosed are conjugate compounds of the following formula: (see above formula) as well as related compounds, and their use to treat proliferative diseases.
Patent CA-2902022-C (CA)
Inventor: FARKAS ATTILA P
IPC: B22C7/02
Filed: 2014-02-07
Granted: 2017-03-21
Abstract: A bonded refractory mold is disclosed. The mold includes a mold wall, the mold wall comprising a bonded refractory material and defining a sprue, a gate and a mold cavity, the gate having a gate inlet opening into the sprue and a gate outlet opening into the mold cavity. The mold also includes a gas vent extending through the mold wall. The mold also includes a gas permeable cover covering the gas vent.
Patent CA-2904483-C (CA)
Title: Cement plug location
Inventor: RADUCANU MARIUS
IPC: E21B47/09
Filed: 2014-03-11
Granted: 2016-10-04
Abstract: The disclosure describes a system and a method for locating a cement plug within a wellbore. The system includes a signal transmitter mounted to the cement plug, a receiver at the opening to the wellbore, one clock positioned on the cement plug and in communication with the transmitter, a second clock which is synchronized to the first clock and in communication with the receiver, and a controller for triggering the transmittal of the signal.
Patent CA-2904735-C (CA)
Title: Methods and compositions for use in oil and/or gas wells
Inventor: HILL RANDAL M
IPC: C09K8/92
Filed: 2015-09-17
Granted: 2019-11-26
Abstract: Methods and compositions comprising an emulsion or a microemulsion for use in various aspects of the life cycle of an oil and/or gas well are provided. In some embodiments, the emulsion or the microemulsion comprises water, a solvent, and a surfactant, and optionally, one or more additives.
Patent CA-2907576-C (CA)
Inventor: ERTL ORTWIN
IPC: C07D307/46
Filed: 2014-03-25
Granted: 2021-05-04
Abstract: Disclosed is a method for the isomerisation of glucose by reduction to sorbitol and subsequent oxidation into fructose, in which the redox cofactors NAD+/NADH and NADP+/NADPH are regenerated in a one-pot reaction, wherein one of the two redox cofactors is obtained in the reduced form thereof while the other redox cofactor is obtained in the oxidized form thereof as a result of at least two additional enzymatically catalysed redox reactions (product forming reactions) taking place in the same reaction batch, wherein (a) in the regeneration reaction, which transfers the reduced cofactor back into its originally oxidised form, oxygen or a compound of the general formula R1C(O)COOH is reduced, and (b) in the regeneration reaction, which transfers the oxidised cofactor back into its originally reduced form, a compound of the general formula R2CH(OH)R3 is oxidised, wherein R1, R2 und R3 have different meanings in the compounds, characterised in that a mixture of glucose and fructose is used as a starting material and by the use of fructose thus produced in a method for producing furan derivatives.
Patent CA-2909013-C (CA)
Inventor: OPHARDT HEINER
IPC: H01M8/1009
Filed: 2015-10-14
Granted: 2023-07-04
Abstract: Une pile à combustible à isopropanol direct adaptée à une utilisation dans des conditions ambiantes et utilisation lisopropanol et de leau contenant de lisopropanol à une concentration relativement élevée (entre 30 % et 90 % disopropanol) comme combustible.
Patent CA-2909843-C (CA)
Title: Appareil de controle de vanne et methode de controle de vanne
Inventor: SUZUKI HIROYUKI
IPC: H01M8/04089
Filed: 2015-10-22
Granted: 2018-07-10
Abstract: Un appareil de commande de soupape commande une soupape pour régler une pression dun gaz de réaction fourni à une pile à combustible. Lappareil de commande de soupape comprend une partie destimation qui estime une section transversale effective de soupape, et une partie de réglage douverture qui règle le degré douverture de la soupape avec une quantité de commande corrigée en fonction de la section transversale effective de soupape estimée par la portion destimation.
Patent CA-2911185-C (CA)
Title: Methods for generating transgenic plants
Inventor: LI XIANGGAN
IPC: C12N15/82
Filed: 2014-06-06
Granted: 2023-09-05
Abstract: This invention provides a method for generating transgenic plants with a low copy number. Plant cells are transformed with polynucleotides containing transcriptional cassettes designed to trigger silencing of a gene which is essential for the plant cell to survive the transformation and regeneration process. The present invention enables the recovery of an increased number of transgenic plants which have only one copy of each desired transcriptional cassette.
Patent CA-2911483-C (CA)
Title: Inhibiteur de la formation de pieges extracellulaires dans les leucocytes
Inventor: HIRAHASHI JUNICHI
IPC: C07K14/79
Filed: 2014-04-08
Granted: 2022-10-04
Abstract: La présente invention concerne un nouveau médicament destiné à inhiber la formation de pièges extracellulaires dans les leucocytes. L'invention concerne un inhibiteur de la formation de pièges extracellulaires dans les leucocytes contenant de la lactoferrine, et une composition pour le traitement des troubles liés à la formation de pièges extracellulaires dans les leucocytes contenant de la lactoferrine.
Patent CA-2912021-C (CA)
Inventor: PARSON NICHOLAS CHARLES
IPC: C22C1/10
Filed: 2014-06-19
Granted: 2020-05-05
Abstract: Un alliage d'aluminium comprend, en pourcentage en poids, de 0,50 à 1,30% de Si, de 0,2 à 0,60% de Fe, de 0,15% maximum de Cu, de 0,5 à 0,90% de Mn, de 0,6 à 1,0% de Mg, et de 0,20% maximum de Cr, le reste étant de l'aluminium et des impuretés inévitables. L'alliage peut comprendre un excès de Mg sur la quantité qui peut être occupée par des précipités de Mg-Si. L'alliage peut être utilisé comme matériau matriciel d'un composite qui comprend un matériau de remplissage dispersé dans le matériau matriciel. Un tel composite peut comprendre du carbure de bore comme matériau de remplissage, et le composite obtenu peut être utilisé dans des applications de blindage neutronique.
Patent CA-2912133-C (CA)
Title: Cxcr7 receptor modulators
Inventor: FRETZ HEINZ
IPC: C07D211/56
Filed: 2014-05-28
Granted: 2021-06-22
Abstract: Abstract The present invention relates to derivatives of formula (I), which are CXCR7 receptor modulators (R1)n R4 L2 Ar.1 R3a, R3b X __Am R2a y R2b Formula (I) wherein (R1)n, R2a, R2b, R3a, R3b, R4, L1, L2, X, Y and Ar1 are as defined herein, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and to their use in preventing and treating diseases, such as cancer, autoimmune disorders, inflammatory diseases, transplant rejection and fibrosis. Date Recue/Date Received 2020-10-22