baber/WOPTO huggingface dataset:
Patent NZ-337476-A (NZ)
Title: Process for the isolation of a pharmaceutically acceptable alkali metal salt of clavulanic acid
Inventor: CARDOSO JOAQUIM P
IPC: C07D503/00
Filed: 1998-03-20
Abstract: A process for the isolation of a pharmaceutically acceptable alkali metal salt of clavulanic acid from a fermentation broth containing impure clavulanic acid comprising the steps of filtration of the fermented broth, extraction of the clavulanic acid to a water immiscible or partly water immiscible solvent at pH from 1.2 - 2, precipitation of sodium clavulanate by addition of a solution of sodium alkyl alkanoate.  The process is characterized by the following steps: before filtration, the fermented broth containing clavulanic acid is pre-diluted with water, a flocculating agent is added and the pH is adjusted to 3 - 5, for further purification the sodium clavulanate is converted to clavulanic acid by addition of an inorganic acid and is extracted into a water immiscible or partly water immiscible solvent; a solution of a different alkali metal, potassium alkyl alkanoate is added and the potassium clavulanate is precipitated
Patent NZ-337698-A (NZ)
Title: Nicotinamide derivatives for selective inhibition of phosphodiesterase type 4 (PDE4) and the production of tumour necrosis factor (TNF) useful for the treatment of respiratory, rheumatoid and allergic diseases
Inventor: MARFAT ANTHONY
IPC: C07D213/82
Filed: 1998-03-10
Abstract: A compound of Formula (I) useful in the treatment of respiratory, allergic, rheumatoid, body weight regulation, inflammatory and central nervous system disorders such as asthma, chronic obstructive pulmonary disease, adult respiratory diseases syndrome, shock, fibrosis, pulmonary hypersensitivity, allergic rhinitis, atopic dermatitis, psoriasis, weight control, rheumatoid arthritis, cachexia, crohn's disease, ulcerative colitis, arthritic conditions and other inflammatory diseases, depression, multi-infarct dementia and AIDS. Wherein; The broken line represents an optional double bond; m is 0 or 1; n is 0 or 1; o is 0, 1, 2, 3 or 4; p is 0 or 1; q is 0, 1, 2 or 3; r is 0, 1, 2, 3, or 4; t is 0 or 1; A is oxygen, NH or sulfur; B is oxygen or NH; D is oxygen or NR9, wherein R9 is hydrogen or C1-6alkyl; E is CH2, O, NH or S(O)a wherein a is 0, 1 or 2; R1 is hydrogen, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkenyl, C6-10aryl, bridgedC7-9bicycloalkyl or a saturated or unsaturated cyclic or bicyclicC3-7heterocyclic group; or R1 cycloalkyl, cycloalkenyl, aryl, bicycloalkyl and heterocyclic groups are additionally optionally independently substituted with from one to three substituents of the Formula (II) wherein R10 is hydrogen, C1-6alkyl, C1-6alkoxy, C3-7cycloalkyl, C3-7cycloalkenyl, C6-10arylamino, C6-10aryl, bridgedC7-9bicycloalkyl or a saturated or unsaturated cyclic or bicyclic C3-7heterocycle; wherein R10 saturated or unsaturated cyclic or bicyclicC3-7heterocycle contains from one to four heteroatoms independently selected from the group consisting of oxygen, sulfur, nitrogen and NR9, or R1 is a group of the Formula (III), wherein u is 0 or 1; and G, J, K and L are each independently oxygen, sulfur, nitrogen, NR9, carbonyl or CHR16; wherein the dashed lines represent optional double bonds and where it is understood that when a double bond exists between G and J, J and K or K and L that R9 is absent, CHR16 is CR16 and G, J, K or L cannot be carbonyl; wherein R16 is hydrogen, halo, cyano, carboxy, amino, nitro, hydroxy, C1-6alkylC1-6alkoxy, C3-7cycloalkyl, hydroxyC1-6alkyl, hydroxyC1-6alkylamino, C1-6alkoxy, difluoromethyl, trifluoromethyl, difluoromethoxy, trifluoromethoxy, C1-6acyl, C1-6acylamino, C1-6acyloxy, C1-6alkylamino, C1-6alkyl)amino, aminosulfonyl, C1-6alkylaminosulfonyl, or a saturated or unsaturated cyclic or bicyclic C3-7heterocycle containing one to four heteroatoms independently selected from the group consisting of oxygen, sulfur, nitrogen and NR9.
Patent NZ-502926-A (NZ)
Title: A pharmaceutical composition containing a therapeutically effective amount of a beta-adrenergic agonist together with a pharmaceutically acceptable bioadhesive for treating dysmenorrhea and premature labour
Inventor: LEVINE HOWARD L
IPC: A61P15/06
Filed: 1998-09-08
Abstract: A composition comprising a beta-adrenergic agonist in a bioadhesive carrier is described.  Preferably, the composition comprises terbutaline (5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol) at a concentration of 0.1% to 0.4% weight/weight in polycarbophil.  The composition is used for treating or preventing dysmenorrhea or premature labour. Using this composition and the method of treatment provides sufficient local levels of the drug to provide therapeutic efficacy, but avoids many untoward adverse events.
Patent NZ-503893-A (NZ)
Title: Method and apparatus for triggering an article containing an oxidizable organic compound
Inventor: BECRAFT MICHAEL L
IPC: B29C35/08
Filed: 1998-10-21
Abstract: A method includes the steps of providing an article comprising an oxidizable organic compound; passing the article through a chamber; exposing the article, while in the chamber, to a source of actinic radiation at a wavelength, intensity and residence time sufficient to provide the article with a dose of actinic radiation of at least 100 mJ/cm2; and exposing the article, while in the chamber, to a source of heat sufficient to raise the temperature inside the chamber to at least 55 DEG F. An apparatus for performing the method is also disclosed.
Patent NZ-504629-A (NZ)
Title: Multilayer film for use in making resealable package, adhesive layer between two outer layers
Inventor: ENGELAERE JEAN-CLAUDE
IPC: B65D8/16
Filed: 2000-05-18
Abstract: A packaging film C, intended for lining the interior of a container consists of a laminate of two polymeric films 2, 4, separated by a layer of pressure sensitive adhesive 3.  The outer layer is a tearable welding layer.  In use, a lid B is welded to the laminate C as shown at D.  When the lid is removed, a portion 9, 10  of layers 4 and 3 is removed with the lid in the vicinity of weld D.  This exposes a portion of adhesive layer 3, which allows the container to be resealed by pressing portion 9 back onto the exposed adhesive.  The film C is formed by blown film co-extrusion, the final film being formed by collapsing the co-extrusion bubble.
Patent NZ-504883-A (NZ)
Title: Refuse-processing unit having a location detecting device consisting of tension element, guide wheel, pre-stressing element and rotational sensor
Inventor: ELBRINK HEINRICH JOHANNES
IPC: B65F3/02
Filed: 1998-12-07
Abstract: A refuse-processing unit, has a location detecting device for detecting the location of a linearly displaceable part (2) of the refuse-processing unit, comprising: a flexible tension means (5) which is connected at one end to the displaceable part (2) of the refuse-processing unit; a guide wheel (7) which is rotatably connected to the frame (1) of the refuse-processing unit and over which the flexible tension means (5) is guided in such a manner that a movement of the flexible tension means (5) triggers a rotation of the guide wheel (7); a prestressing means which is connected to the other end of the flexible tension means (5); and a rotation sensor (8) for detecting a certain rotation of the guide wheel (7).
Patent NZ-507024-A (NZ)
Title: Biocidal benzylbiphenyl derivatives
Inventor: MEERPOEL LIEVEN
IPC: C07C/
Filed: 1999-03-25
Abstract: A compound of formula (I), wherein; X is absent when the dotted line represents a bond, or X is hydrogen or hydroxy, when the dotted line does not represent a bond, R1 and R2 are each independently selected from hydrogen, halogen, hydroxy, C1-4alkyl, C1-4alkyloxy, nitro, amino, cyano, trifluoromethyl, trifluoromethoxy, C1-6alkylcarbonyl, hydroxycarbonyl, C1-6alkyloxycarbonyl, aminocarbonyl, di(C1-4alkyl)aminocarbonyl, C1-6alkylsulfinyl, C1-6alkylsulfonyl, aminosulfonyl, di(C1-4alkyl)aminosulfonyl, or -SO3H, R3 and R4 are each independently selected from hydrogen, halogen, hydroxy, C1-4alkyl, C1-4alkyloxy, nitro, amino, cyano, trifluoromethyl, or trifluoromethoxy, R5 and R6 are each independently selected from hydrogen, halogen, halogen, hydroxy, C1-4alkyl, C1-4alkyloxy, nitro, amino, cyano, trifluoromethyl, trifluoromethoxy, C1-6alkylcarbonyl, hydroxycarbonyl, C1-6alkoxycarbonyl, aminocarbonyl, di(C1-4alkyl)aminocarbonyl, C1-6alkylsulfinyl, C1-6alkylsulfonyl, aminosulfonyl, di(C1-4alkyl)aminosulfonyl, or -SO3H, L is a radical of formulae (a-1), (a-2), (a-3), (a-4), (a-5), (a-6), (a-7), (a-8), (a-9) and (a-10). Also described is the use of the compounds of formula (I) as biocides.
Patent NZ-507611-A (NZ)
Title: A device for unloading containers/baggage trays on a conveyor
Inventor: LECROY DONALD L
IPC: B65G47/40
Filed: 1999-04-19
Abstract: The tipper (22) comprises a section of belt conveyor (28) mounted on a movable platform (30).  The platform includes a leading edge (31) and a trailing edge (33).  The platform (30) includes rail members (32), which hold a tray (14).  A portion (34) of each tray (14) is positioned under the rails (32) to hold the tray on the tipper (22) while it is being tipped.  The platform (30) is mounted on two sets of wheels; a leading set (36), which is spaced apart by a first distance, and a trailing set (38), which is spaced apart by a second distance.  Separate supports (40, 42) are provided for each set of wheels.  The platform (30) is pushed in the direction of the leading wheels (36) by a linear actuator (48).
Patent NZ-509005-A (NZ)
Title: Apparatus and method for processing signals selected from multiple data streams received from terrestrial transmitters or satellites
Inventor: TAWIL CARMEN
IPC: H04N21/438
Filed: 1999-05-27
Abstract: An apparatus (10) for receiving multiple data streams comprises: (a) a first switch (31) connected to a first input (11), the first switch has a first switch output, the first switch adapted to be selectively enabled for passing a first stream of data signals from the first input to the first switch output, the first stream of data signals includes first channel data; (b) a second switch (32) connected to a second input (12), the second switch has a second switch output, the second switch adapted to be selectively enabled for passing a second stream of data signals from the second input to the second switch output, the second stream of data signals includes second channel data different from the first channel data; (c) a data stream junction (36) connected to the first switch output and the second switch output, the data stream junction has a junction output; (d) a controller (43) for receiving a channel select input related to a desired channel output to be formed from one of the first channel data or second channel data, and, in response to the channel select input, the controller enables one of the first switch or the second switch which receives the stream of data including the channel data from which the desired channel output is to be formed; and (e) a memory device (47) operatively connected to the controller, the memory device stores first signal input information indicating the respective switch through which the first channel data is received and further the memory device stores second signal input information indicating the respective switch through which the second channel data is received. The apparatus described above further includes: (a) a signal processor (14) to receive data signals from the data stream junction, the controller controls the operation of the signal processor to produce the desired channel output from data signals received from the data stream junction, and/or (b) a satellite receiving antenna (21) oriented to receive signals transmitted directly from a satellite transmitter, the first stream of data signals includes data received through the satellite receiving antenna, and/or (c) a terrestrial receiving antenna (22) oriented to receive signals transmitted directly from a terrestrial transmitter, the second stream of data signals includes data received through the terrestrial receiving antenna.
Patent NZ-509484-A (NZ)
Title: A system and method for packaging and orientating containers based on an index mark or advertising material on the container
Inventor: LAM ROBERT
IPC: B65B21/04
Filed: 2001-01-19
Abstract: A system for use with a packing machine for orienting containers in a container carrier, the system comprising: an inlet conveyor for feeding a plurality of un-oriented containers into an inlet; an orientation wheel connected to the inlet, the orientation wheel adapted to rotate each un-oriented container into a proper orientation resulting in a plurality of oriented containers; a transfer belt connected with respect to the orientation wheel, the transfer belt having a tactile member contacting a sidewall  of the oriented container to maintain orientation of the oriented container and transfer each oriented container in a fixed rotational position from the orientation wheel to the packing machine; and a mechanism positioned within the packaging machine for applying the container carrier over two or more containers.
Patent NZ-510602-A (NZ)
Title: Radioactive source sealed in a bicompatible roughened container for use in brachytherapy
Inventor: MCINTIRE GREGORY LYNN
IPC: A61K51/00
Filed: 1999-11-05
Abstract: A radioactive source for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or smoothed or otherwise treated so that it is no longer smooth.
Patent NZ-517727-A (NZ)
Title: A method of managing organisational improvements using a database
Inventor: POTTER DAVID GEORGE
IPC: G06F17/30
Filed: 2002-03-12
Abstract: An electronic method of managing information comprises creating information at an originating source; electronically generating and electronically forwarding notification of the information to a designated location; logging and storing details of the information in a database held in an electronic data processing means; electronically returning the original notification to the originating source; periodically electronically forwarding updated information from the originating source to the designated location, the updated information being added to the original notification and periodically electronically compiling reports and/or notices from the database.
Patent NZ-518342-A (NZ)
Title: AB5 toxin B subunit mutants with altered chemical conjugation characteristics
Inventor: HANDLEY HAROLD H
IPC: C07K14/235
Filed: 2000-10-05
Abstract: The use of a cholera Toxin B (CTB) subunit for treating or preventing an auto immune disease is disclosed. Preferably the CTB subunit protein has the N-terminal sequence TPQNIT or APQNIT and may be produced in a bacterial host system.
Patent NZ-518366-A (NZ)
Title: Zwitterionic siloxane polymers and ionically cross-linked polymers formed therefrom
Inventor: GORMLEY JOHN L
IPC: A61Q15/00
Filed: 2000-10-26
Abstract: Ionically cross-linked silicone polymers of a thickened gel-like consistency are made by reacting a diamino containing polysiloxane with an acid containing reactant selected from itaconic acid or the ester derivative thereof; substituted or unsubstituted cyclic and ankydride; substituted or unsubstituted conjugated olefinic acid or mixtures of the same at an elevated temperature in the presence of a low molecular weight silicone oil or other solvent until an ionically cross-linked zwitterionic siloxane polymer of a gel-like consistency is formed. Also described are cosmetics and coating materials comprising the polysiloxanes of the invention.
Patent NZ-518662-A (NZ)
Title: Endogenous and non-endogenous versions of human G protein-coupled receptors
Inventor: CHEN RUOPING
IPC: C12N5/10
Filed: 2000-11-16
Abstract: Disclosed is a G protein-coupled receptor encoded by an amino acid sequence of SEQ. ID. NO. : 22 and the related nucleic acid sequence. Also disclosed are non-endogenous, constitutively activated version of this G protein-coupled receptor, plasmids comprising a vector and the cDNA of SEQ. ID. NO. : 21, and host cells comprising such plasmids. Compounds suitable for modulating the receptor are also discussed, such compounds being useful in the treatment of diabetes or related conditions such as defects in glucagon or insulin regulation .
Patent NZ-521379-A (NZ)
Title: Improvements to louvre windows
Inventor: CHASTON KEITH JAMES
IPC: E06B7/084
Filed: 2001-03-01
Abstract: A louvre locking mechanism to lock a plurality of louvres in a louvre window, the locking mechanism comprising an elongate slide member (35) which is slidable between a louvre locking position and an unlocking position, an operating means to operate the slide member and a plurality of engagement means on the slide member, each engagement means engageable with a louvre, whereby the louvres can be closed in the normal manner, and the slide member can be operated to its locking position which causes the engagement means to engage with the louvres. Louvre operating mechanisms and sealing means are also disclosed.
Patent NZ-524197-A (NZ)
Title: Method for the diagnosis of cancer using matrix assisted laser desorption/ionisation time of flight mass spectrometry (MALDI-TOF MS) or electrospray MS
Inventor: PARISH CHRISTOPHER RICHARD
IPC: G01N27/64
Filed: 2001-07-19
Abstract: A mass spectrometry-based method of identifying a cancer marker in sera is described and uses of the cancer marker in diagnosing cancer in human and non-human subjects. Isolated cancer markers are also provided.
Patent NZ-524431-A (NZ)
Title: Protein extracted from the intestines of vertebrates, which absorbs cholesterol, and the use of this protein for identifying inhibitors of intestinal cholesterol transport
Inventor: KRAMER WERNER
IPC: A61K35/38
Filed: 2001-08-18
Abstract: A process for obtaining a cholesterol-absorbing protein from the intestinal tissue of a mammalian organism is disclosed, wherein the process comprises the following process steps: (a) provision of intestinal cells or organelles of intestinal cells of a mammalian organism, wherein said intestinal cells or organelles of intestinal cells are not within a living human being, (b) provision of a radiolabeled compound which acts as inhibitor of intestinal cholesterol absorption and contains a photolabile group, (c) contacting the intestinal cells or organelles of intestinal cells from (a) with a compound from (b), (d) irradiation of the mixture from (c) with UV light, (e) disruption of the cells after irradiation as in (d), (f) fractionation of the components of the disrupted cells after disruption as in (e), (g) detection, after fractionation as in (f), of a protein which contains a covalently bound compound from (b). The protein could be identified using highly affine cross-linking compounds. The disclosure also relates to the use of this protein for carrying out a method for identifying a compound, which inhibits cholesterol transport in the intestines.
Patent NZ-524452-A (NZ)
Title: Fish farming system and method comprising a fish cage of controllable buoyancy
Inventor: ZEMACH SHALOM
IPC: A01K61/00
Filed: 2001-07-24
Abstract: A deep-water fish farming system is disclosed comprising a fish cage (200) of controllable buoyancy having one or more chambers (202), which can be submerged and refloated at a controllable rate to any depth. A winch mechanism (214) mounted preferably on a platform (210) that covers a section of the cage (200) release and gathers a cable (212) connected to a sinker (216). When the combined weight of the system overcomes the buoyancy, the fish cage (200) is submerged to a depth determined by the effective length of the cable (212) between the winch mechanism (214) and the sinker (216), with the sinker (216) touching the sea bottom. When the cage (200) is refloated to the surface, the buoyancy is increased to allow pulling of the sinker (216) from the bottom. A method is further disclosed for submerging and raising a fish cage (200) at a controlled rate to any desired depth in deep water.
Patent NZ-529068-A (NZ)
Title: Implantation serine proteinases
Inventor: RANCOURT DERRICK E
IPC: A61K48/00
Filed: 2002-04-08
Abstract: This invention provides two novel serine proteinases that are important for female fertility, particularly in the process of hatching and implantation. These proteinases, as well as the nucleic acids, fragments, analogs, and/or inhibitors thereof, can be used to modulate hatching, implantation and female fertility in general.
Patent NZ-529256-A (NZ)
Title: 4-amino-5-phenyl-7-cyclobutyl-pyrrolo (2,3-d) pyrimidine derivatives
Inventor: CAPRARO HANS-GEORG
IPC: A61P35/00
Filed: 2002-05-13
Abstract: Derivatives of 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine which are of formula I are disclosed. Processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof-alone or in combination with one or more other pharmaceutically active compounds-for the treatment of a disease, especially a proliferative disease, such as a tumour disease by inhibition of the IGF-IR tyrosine kinase, a method for the treatment of such diseases in mammals, especially in humans, and the use of such a compound-alone or in combination with one or more other pharmaceutically active compounds-for the preparation of a pharmaceutical composition (medicament) for the treatment especially of a proliferative disease, such as a tumour is also disclosed.
Patent NZ-529314-A (NZ)
Title: Inhibitors of receptor activator of NF-kappaB and uses thereof
Inventor: AGGARWAL BHARAT
IPC: A61P35/00
Filed: 2002-05-10
Abstract: Polypeptide inhibitors of TNF receptor-associated factor 6 (TRAF6) comprising a TRAF6 binding domain and a leader signal sequence. The polypeptide inhibitors used in the preparation of a medicament for treating metabolic bone disorders, leukaemia, multiple myeloma, arthritis and metastatic cancer of the bone due to inhibition of cellular receptor activation of NF-kappaB (RANK) ligand induced osteoclast differentiation through inhibition of RANK and TRAF6 interaction.
Patent NZ-530191-A (NZ)
Title: Non-pathogenic, spore-forming, Gram-positive, lipophilic bacterial strain that produces extracellular lipase and also hydrolyses fatty acids and grease
Inventor: DRAHOS DAVID J
IPC: C12N1/20
Filed: 2002-04-26
Abstract: Described is a Gram-positive microorganism, Bacillus megaterium , strain SB3112, that effectively and degrades fats, oils and grease. A composition comprising this microorganism and a method for degrading fatty acids and grease are also disclosed. Availability of glycerol to the biodegrading microorganism was discovered to enhance biodegradation. Figure 1 shows the efficacy of various microorganisms to degrade grease.
Patent NZ-536752-A (NZ)
Title: Method and apparatus for protecting monitor circuit from fault condition
Inventor: GOODMAN CARL E
IPC: H02H9/02
Filed: 2003-04-29
Abstract: A method and apparatus for improving the fault protection of a monitor circuit (10) by coupling an input protection circuit to an output section (34) is disclosed. The input protection has a first input (12), a second input (14) connected to ground, and a control node. A fusible element is coupled between the first input and control node and is configured to protect the monitor circuit from a fault condition on the first input, where the fault condition is a periodic signal. The isolated output section (34) is optically coupled (24) to the input protection circuit and will produce an output signal upon occurrence of a triggering event at the first input. The output signal is an asserted steady-state signal when the triggering event is a coupling between the first and second inputs, and is a periodic signal when the triggering event is the periodic signal on the first input.