baber/WOPTO huggingface dataset:
Patent MX-2010010429-A (MX)
Title: Method for crystallization of 2-amino-2-[2-[4-(3- benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol hydrochloride.
Inventor: KOMATSU HIDETAKA
IPC: C07C323/32
Filed: 2009-03-18
Abstract: Disclosed is a process for producing a highly pure crystal of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]- ethyl]-1,3-propanediol hydrochloride with high efficiency. The process comprises the following steps (1) and (2): (1) dissolving 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2- chlorophenyl]ethyl]-1,3-propanediol in a mixed solvent composed of a solvent having high solubility to 2-amino- 2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3- propanediol hydrochloride and a solvent having poor solubility to 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2- chlorophenyl]ethyl]-1,3-propanediol hydrochloride to prepare a solution of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2- chlorophenyl]ethyl]-1,3-propanediol; and (2) adding hydrochloric acid to the solution while agitating the solution to cause the crystallization of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2- chlorophenyl]ethyl]-1,3-propanediol hydrochloride.
Patent MX-2010010663-A (MX)
Title: Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery.
Inventor: ARPS JAMES H
IPC: A61L29/08
Filed: 2009-03-27
Abstract: The present invention provides insertable medical devices having elastic surfaces associated with bioactive agent-containing microparticulates and a coating material. Upon expansion of the elastic surfaces the microparticulates can be released to a subject.
Patent MX-2010011384-A (MX)
Title: System for the expression of peptides on the bacterial surface.
Inventor: GARCIA JOSE DE LA FUENTE
IPC: C12N15/70
Filed: 2009-04-16
Abstract: The invention relates to a system for the expression of peptides on the bacterial surface, characterised in that the conserved sequence of the MSP1a protein of Anaplasma marginale is used as the membrane-binding site.<i/>.
Patent MX-2010012393-A (MX)
Title: Systems and methods for producing reduced cholesterol dairy products.
Inventor: SALINAS EDWARD
IPC: A23C9/14
Filed: 2009-05-12
Abstract: A reduced cholesterol cream, as compared to a conventionally prepared cream, is produced by pressurizing and shearing whole milk prior to separation of the whole milk into skim milk and cream. The skim milk is increased in cholesterol content and the cream is reduced in cholesterol content.
Patent MX-2011000038-A (MX)
Title: Tarping system for flatbed trailers.
Inventor: STEVENSON BRYCE ARNOLD
IPC: B60P7/04
Filed: 2009-06-25
Abstract: An assembly including a frame is attached to the fork carrier of a forklift. The assembly picks up a tarp to cover the cargo on a flatbed trailer. The tarp is secured under the frame on the assembly and the forklift elevates the frame and tarp above the cargo and drapes the tarp over the cargo by firstly driving along side the trailer and secondly lowering the frame. Eyes, loops, D-rings or the like on the corners and mid-section of the tarp are held in hooks slidably mounted on the ends of the frame members. A pivotable lever arm lifts the eyes, loops, D-rings, or the like from the hooks to allow the tarp to settle on the load.
Patent MX-2011000921-A (MX)
Title: Porcine circovirus type 2, jalisco subtype multiplied in kidney cells of african green monkey (vero) for the preparation of an inactivated vaccine against porcine circovirus.
Inventor: PEREZ LOURDES ROMERO
IPC: A61K39/00
Filed: 2011-01-24
Abstract: The invention refers to a virus strain of porcine circovirus type 2 Jalisco subtype, isolated in the state of Jalisco and multiplied in the VERO cell substrate (cells of African green monkey). The invention consists in the elaboration of an inactivated vaccine against Porcine Circovirus, which is based on the adaptation of the Porcine Circovirus type 2, Jalisco subtype virus to be multiplied in the VERO cell line, by carrying out 3 blind passages and 5 consecutive passages for reaching the title of 1 X 105.5 DICC50%/mL. The vaccine is formulated with the viral fluid cultured and inactivated with ß-propiolactone plus Montanide TM Gel adjuvant, which applied to healthy and susceptible porks stimulates the production of specific antibodies that provide protection against the Porcine Circovirus.
Patent MX-2011001383-A (MX)
Title: Bioassay for polyq protein.
Inventor: PAGANETTI PAOLO
IPC: G01N33/68
Filed: 2009-08-03
Abstract: The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diagnostic tools, for monitoring disease progression or for monitoring the efficacy of treatment of the disease. In a preferred embodiment the polyQ-protein is polyQ-huntingtin.
Patent MX-2011001832-A (MX)
Title: Compounds for the treatment of peripheral neuropathies.
Inventor: LEPPERT DAVID
IPC: A61K31/452
Filed: 2009-08-17
Abstract: A compound of formula A1 or A2 for use in the treatment of a demyelinating peripheral neuropathy: wherein A is COOR<sub>5</sub>, OPO(OR<sub>5</sub>)<sub>2</sub>, PO(OR<sub>5</sub>)<sub>2</sub>, SO<sub>2</sub>OR<sub>5</sub>, POR<sub>5</sub>OR<sub>5</sub> or 1<i>H</i>-tetrazol-5-yl, R<sub>5</sub> being H or an ester-forming group, optionally C<sub>1-6</sub>alkyl; W is a bond, C<sub>1-3</sub>alkylene or C<sub>2-3</sub>alkenylene; Y is C<sub>6-10</sub>aryl or C<sub>2-9</sub>heteroaryl eg C<sub>3-9</sub>heteroaryl, optionally substituted by 1 to 3 radicals selected from halogen, OH, NO<sub>2</sub>, C<sub>1-6</sub>alkyl, C<sub>1-6</sub>alkoxy; halo-substituted C<sub>1-6</sub>alkyl and halo-substituted C<sub>1-6</sub>alkoxy; Z is chosen from Formula (I) : wherein the asterisks of Z indicate the point of attachment between -C(R<sub>3</sub>)(R<sub>4</sub>)- and A of Formula (Ia) or (Ib), respectively; R<sub>6</sub> is chosen from hydrogen and C<sub>1-6</sub>alkyl; and J<sub>1</sub> and J<sub>2</sub> are independently methylene or a heteroatom chosen from S, O and NR<sub>5</sub>; wherein R<sub>5</sub> is chosen from hydrogen and C<sub>1-6</sub>alkyl; and any alkylene of Z can be further substituted by one to three radicals chosen from halo, hydroxy, C<sub>1-6</sub>alkyl; or R<sub>6 </sub>can be attached to a carbon atom of Y to form a 5-7 member ring; R<sub>1</sub> is C<sub>6-10</sub>aryl or C<sub>2-9</sub>heteroaryl eg C<sub>3-9</sub>heteroaryl, optionally substituted by C<sub>1-6</sub>alkyl, C<sub>6-10</sub>aryl, C<sub>6-10</sub>arylC<sub>1-4</sub>alkyl, C<sub>3-9</sub>heteroaryl, C<sub>3-9</sub>heteroarylC<sub>1-4</sub>alkyl, C<sub>3-8</sub>cycloalkyl, C<sub>3-8</sub>cycloalkylC<sub>1-4</sub>alkyl, C<sub>3-8</sub>heterocycloalkyl or C<sub>3-8</sub>heterocycloalkylC<sub>1-4</sub>alkyl; wherein any aryl, heteroaryl, cycloalkyl or heterocycloalkyl of R<sub>1</sub> may be substituted by 1 to 5 groups selected from halogen, C<sub>1-6</sub>alkyl, C<sub>1-6</sub>alkoxy and halo substituted-C<sub>1-6</sub>alkyl or -C<sub>1-6</sub>alkoxy; R<sub>2</sub> is H, C<sub>1-6</sub>alkyl, halo substituted C<sub>1-6</sub>alkyl, C<sub>2-6</sub>alkenyl or C<sub>2-6</sub>alkynyl; and each of R<sub>3</sub> and R<sub>4</sub>, independently, is H, halogen, OH, C<sub>1-6</sub>alkyl, C<sub>1-6</sub>alkoxy or halo substituted C<sub>1-6</sub>alkyl or C<sub>1-6</sub>alkoxy; and the N-oxide derivatives thereof or prodrugs thereof, or a pharmacologically acceptable salt, solvate or hydrate thereof.
Patent MX-2011004295-A (MX)
Title: Quinazoline derivatives as nk3 receptor antagonists.
Inventor: RIEMER CLAUS
IPC: C07D409/14
Filed: 2009-11-04
Abstract: The present invention relates to a compounds of formula I wherein R<sup>1</sup> is hydroxy or NR'R"; R' and R" are independently from each other hydrogen, lower alkyl, cycloalkyl, or may form together with the N-atom to which they are attached a heteroalkyl ring; R<sup>2</sup> is hydrogen, lower alkyl, lower alkoxy, halogen, lower alkyl substituted by halogen, lower alkoxy substituted by halogen, cyano or S(O)2-Iower alkyl; R<sup>3</sup> is lower alkyl, -(CH2)m-aryl, optionally substituted by halogen, or is -(CH2)m-cycloalkyl; R<sup>4</sup> and R<sup>5</sup> are independently from each other hydrogen or lower alkyl substituted by halogen, or are -(CR2)m-aryl or -(CR2)m-heteroaryl, wherein the rings may be substituted by one or more substituents, selected from halogen, lower alkyl, lower alkyl substituted by halogen, cyano, hydroxy, NR'R" or by lower alkoxy substituted by halogen, or are -(CR2)m-cycloalkyl, optionally substituted by hydroxy or by aryl, or are a heteroalkyl ring, optionally substituted by =O or -(CR2)m-aryl, or R<sup>4</sup> and R<sup>5</sup> are together with the N-atom to which they are attached a heterocyclic ring system, optionally substituted by lower alkyl, aryl or halogen-substituted aryl, and R may be independently from each other hydrogen, lower alkyl or lower alkyl substituted by hydroxyl; n is 1 or 2; m is 0, 1 or 2; or to a pharmaceutically active salt, a racemic mixture, an enantiomer, an optical isomer or a tautomeric form thereof. It has been found that the present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
Patent MX-2011006338-A (MX)
Title: A coating composition comprising polymer encapsulated metal oxide opacifying pigments and a process of producing the same.
Inventor: LUNDGARD RICHARD
IPC: C09D7/62
Filed: 2009-11-23
Abstract: The instant invention provides a coating composition, a process of making a coating composition, a coated article, and a method of making such articles. The coating composition according to the present invention comprises: (a) a dispersion comprising; one or more base polymers; at least one first pigment partially encapsulated by said one or more base polymers, wherein said first pigment is a metal oxide selected from the group consisting of TiO2, SiO2, ZnO, A12O3, combinations thereof; optionnaly one or more stabilizing agents; and a liquid media; and (b) optionnaly a binder composition.
Patent MX-2011007239-A (MX)
Title: Auto-feed utility knife.
Inventor: DEURSEN GARY VAN
IPC: B26B1/08
Filed: 2010-01-15
Abstract: A utility knife having a knife body, a movable blade holder inside the knife body for slidably moving a flat blade and a blade retaining arm selectively engageable with the blade for removably retaining the flat blade on the blade holder, and a blade release button engageable with the blade retaining arm for disengaging the blade retaining arm from the blade. The blade release button is slidably mounted in the knife body and movable in a direction substantially parallel to a major plane of the flat blade such that sliding the blade release button moves the blade retaining arm to disengage the blade retaining arm from the blade.
Patent MX-2012000919-A (MX)
Title: Device for selectively depositing molten plastic materials.
Inventor: PLANTA TORRALBA FRANCISCO JAVIER
IPC: B29B13/02
Filed: 2010-07-21
Abstract: Device for selectively depositing molten plastic materials. It comprises a support (3), an ultrasonic transducer (1), a sonotrode (2), a nozzle (4), at an end part of said sonotrode, and a melting chamber (5) in communication with a deposition outlet (4a) trough a discharging channel (6a) wherein: â ¢ an internal channel (6) extends through the sonotrode (2) allowing a loose passage of plastic material in solid state; â ¢ said internal channel (6) extends along a section with a progressive reduction of its clearance area through a truncated conical section providing said discharging channel (6a) and containing said melting chamber (5); â ¢ several longitudinal profiles or ribs (10), located as a cone generator and angularly offset are protruding from the interior wall of the conical section of the melting chamber (5), having a multifaceted end (11) facing and opposed to an entrance to said melting chamber (5).
Patent MX-2012001730-A (MX)
Title: A bio-denitrification apparatus and method for making and using same.
Inventor: GALGON RANDY A
IPC: C02F3/12
Filed: 2010-08-11
Abstract: A denitrification system is disclosed, where a plurality of biological regenerated adsorptive cells or units. Each cell includes a counterflowing absorptive media and waste water to achieve a two or three zone biomass nitrate/nitrite degradation environment. The system includes a backwash water recirculation loop and a media recirculation loop, where the media recirculation loop subjects the media a sufficient shear to dislodge dead microbes and/or weakly bound microbial films from the media surface, but insufficient to substantially reduce the particle size of the friable media. Nutrient supply and distribution and gas controls are used regulate cell characteristics.
Patent MX-2012003331-A (MX)
Title: Shared face training data.
Inventor: THORNTON JOHN M
IPC: G06F21/20
Filed: 2010-09-15
Abstract: Face data sharing techniques are described. In an implementation, face data for a training image that includes a tag is discovered in memory on a computing system. The face data is for a training image that includes a tag associated with a face. The face data is replicated in a location in memory, on another computing system, so the face data is discoverable.
Patent MX-2012003503-A (MX)
Title: Game system and game apparatus.
Inventor: MATSUNO MASAKI
IPC: A63F13/45
Filed: 2010-09-24
Abstract: Disclosed is a game system provided with a lottery apparatus connected so as to allow exchange of information with a plurality of player terminal devices; wherein the lottery apparatus has rotatable bodies of a number that is identical to the number of rows M or the number of columns N of a card, the rotatable bodies are associated with each row or each column and perform a lottery, and the player terminal device has an arrangement determination unit, which matches the symbol to be associated with a square included in each of the rows or the columns of the card with the symbol determined by the lottery that has been performed by the rotatable body that has been associated with each of the rows or the columns, and sets the arrangement thereof.
Patent MX-2012004536-A (MX)
Title: Method and device for treating a substrate surface of a substrate.
Inventor: SCHMID CHRISTIAN
IPC: H01L31/18
Filed: 2010-07-28
Abstract: In a method for treating a substrate surface of a flat substrate with a process medium on the lower side of the substrate, the process medium has a removing or etching effect on the substrate surface. The substrates are wetted from beneath with the process medium while lying horizontally. The upwardly directed upper side of the substrate is wetted or covered over a large surface area or completely with water or a corresponding protective liquid as protection against the action of the process medium on the upper side of the substrate.
Patent MX-2012005532-A (MX)
Title: Drug combination with theobromine and its use in therapy.
Inventor: BANNISTER ROBIN MARK
IPC: A61K31/522
Filed: 2010-11-12
Abstract: An agent comprises theobromine and another non-opiate antitussive, for simultaneous, sequential or separate use in therapy. Preferably, the therapy is of cough.
Patent MX-2012005781-A (MX)
Title: Apparatus for providing an upmix signal represen.
Inventor: PURNHAGEN HEIKO
IPC: G10L19/008
Filed: 2010-11-16
Abstract: An apparatus for providing an upmix signal representation on the basis of a downmix signal representation and an object-related parametric information, which are included in a bitstream representation of an audio content, in independence on a user-specified rendering matrix, the apparatus comprises a distortion limiter configured to obtain a modified rendering matrix using a linear combination of a user-specified rendering matrix in a target rendering matrix in dependence on a linear combination parameter. The apparatus also comprises a signal processor configured to obtain the upmix signal representation on the basis of the downmix signal representation and the object-related parametric information using the modified rendering matrix. The apparatus is also configured to evaluate a bitstream element representing the linear combination parameter in order to obtain the linear combination parameter.
Patent MX-2012010391-A (MX)
Title: Imidazo [1, 2 -a] pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.
Inventor: VANHOOF GRETA CONSTANTIA PETER
IPC: C07D487/04
Filed: 2011-03-08
Abstract: The present invention relates to novel imidazo[1,2-a]pyrazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.
Patent MX-2012010444-A (MX)
Title: Playset with dynamic transfer.
Inventor: SMOKOWSKI JOHN THADDEUS
IPC: A63H18/00
Filed: 2012-09-10
Abstract: The present invention is directed toward an interactive playset with a slide/ramp including an entrance area at the top of the slide and an exit area at the bottom of the slide. The playset further includes a dynamic transfer system that transfers the accessory from the slide exit back to the slide entrance. The dynamic transfer system includes a plurality of stepped platforms, each platform having a piston that is selectively engaged to drive the accessory from a lower platform to an upper platform.
Patent MX-2012013560-A (MX)
Title: Substituted-6-methylnicotinamides as mglur5 positive allosteric modulators.
Inventor: MACDONALD GREGOR JAMES
IPC: A01N43/40
Filed: 2011-05-24
Abstract: In one aspect, the invention relates to substituted 6-methylnicotinamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Patent MX-2012014788-A (MX)
Title: Pharmaceutical compositions for sublingual delivery of opioids.
Inventor: SAMS MARTIN JAMES
IPC: A61K31/137
Filed: 2011-06-29
Abstract: The invention provides pharmaceutical compositions for the sublingual delivery of opioids. The invention also provides delivery devices adapted for sublingual delivery of such compositions.
Patent MX-2013000103-A (MX)
Title: Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase.
Inventor: FRAYSSE DAMIEN
IPC: C07D519/00
Filed: 2011-06-23
Abstract: The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.
Patent MX-2013000651-A (MX)
Title: Method for the identification of catechol o-methyltransferase modulators.
Inventor: ENDERLE THILO
IPC: G01N33/573
Filed: 2011-07-25
Abstract: The present invention relates to a method for the identification of modulators of catechol O-methyltransferase enzyme activity (COMT).
Patent MX-2013001412-A (MX)
Title: Compositions comprising at least one compound containing a carbamoyl sulfonate group and use of the same as tanning agents.
Inventor: REINERS JUERGEN
IPC: C14C3/08
Filed: 2011-07-28
Abstract: The invention relates to an aqueous composition containing a) at least one compound containing a carbamoyl sulfonate group and b) at least one non-ionic alkoxylated polyol containing ester groups and having a HLB value of at least 13 (b1) and/or an alkylglycoside (b2).
Patent MX-2013001921-A (MX)
Title: Dual image sensor image processing system and method
Inventor: COTE GUY
IPC: H04N5/232
Filed: 2011-08-11
Abstract: Various techniques are provided for processing image data acquired using a digital image sensor 90  In accordance with aspects of the present disclosure, one such technique may relate to the processing of image data in a system 10 that supports multiple image sensors 90  In one embodiment, the image processing system 32 may include control circuitry configured to determine whether a device is operating in a single sensor mode (one active sensor) or a dual sensor mode (two active sensors)  When operating in the single sensor mode, data may be provided directly to a front-end pixel processing unit 80 from the sensor interface of the active sensor  When operating in a dual sensor mode, the image frames from the first and second sensors 90a, 90b are provided to the front-end pixel processing unit 80 in an interleaved manner  For instance, in one embodiment, the image frames from the first and second sensors 90a, 90b are written to a memory 108, and then read out to the front-end pixel processing unit 80 in an interleaved manner
Patent MX-2013003616-A (MX)
Title: Unified reconnection to multiple remote servers.
Inventor: HENRIQUEZ ALBERTO
IPC: H04L69/14
Filed: 2011-09-14
Abstract: Techniques are disclosed for connecting a user to all of his resources (e.g. remote desktop or remote application) in a deployment of server farm(s). The user's client sends a message to the deployment requesting any disconnected resources for the user and/or any active resources communicating with a different client. The deployment determines what those resources are, then strips out redundant information (e.g. two resources are remote applications executing within the same session) and sends a stripped list to the client, which reconnects. The client first reconnects to a resource that is not a VM and stores any user input (e.g. credentials) prompted for during that log in. Then, it reconnects to the other resources in parallel, using in these later reconnections any input received from the client during the first reconnection.
Patent MX-2013007459-A (MX)
Title: Radiation curable coating compositions for metal.
Inventor: MILLER PATRICIA
IPC: C09D175/16
Filed: 2011-12-23
Abstract: Various embodiments of radiation curable coating compositions are provided. In one embodiment, a radiation curable coating composition includes a (meth)acrylate functional compound and an adhesion promoting (meth)acrylate compound. The radiation curable coating composition can also include a (meth)acrylate functional compound, a poly(meth)acrylate and a reactive diluent. The (meth)acrylate functional compound can be made from the reaction of a multifunctional isocyanate, a polyol and a hydroxyl functional (meth)acrylate in the presence of a catalyst.
Patent MX-2013007611-A (MX)
Title: Methods for cryopreserving and encapsulating cells.
Inventor: ABRAMSON SASCHA
IPC: A61K35/12
Filed: 2011-12-29
Abstract: Described herein are methods of cryopreserving cells that have been suspended in alginate as well as methods for encapsulating cryopreserved cells that have been suspended in alginate. Further provided herein are cellular compositions comprising cells that have been processed in accordance with the methods described herein.