baber/WOPTO huggingface dataset:
Patent CA-2898939-A1 (CA)
Title: Tridentate linkers and use thereof
Inventor: AN DEQIANG
IPC: A61K39/395
Filed: 2014-01-17
Abstract: Disclosed are a tridentate connexon and use thereof. The tridentate connexon can be used to prepare an antibody-drug conjugate as represented by formula I, wherein L is an antibody, antibody segment or protein; T is a tridentate connexon part; A is a cleavable connexon combination or an un-cleavable connexon part; D is a drug part; and n is an integer in the range from 0 to 8. The structure of the tridentate connexon part is as represented by formula II, wherein W is a substituted aryl, heteroaryl, chain alkyl, cycloalkyl, heterocyclic alkyl, or any combination thereof.
Patent CA-2898991-A1 (CA)
Inventor: MORRISS JOHN
IPC: A61F2/24
Filed: 2014-02-04
Abstract: La présente invention concerne des systèmes, des appareils et des méthodes permettant de traiter des valvules cardiaques natives. Un système de mise en place d'un dispositif prothétique dans le cur d'un patient comprend un corps de cathéter allongé et une capsule de mise en place. La capsule de mise en place peut être actionnée de façon hydraulique afin d'assurer le déploiement d'au moins une partie d'un dispositif de type prothèse de valvule cardiaque. La capsule de mise en place peut libérer le dispositif de type prothèse de valvule cardiaque sur le site de traitement sélectionné chez le patient.
Patent CA-2902236-A1 (CA)
Title: Methode de production d'un plan de sequence de trous de forage et equipement de planification de sequence de trous de forage
Inventor: OPPOLZER FLORIAN
IPC: E21B43/30
Filed: 2014-02-25
Abstract: Selon l'invention, un équipement de planification de séquence de trous de forage (14) comprend un module de détermination de position (18) permettant de déterminer un emplacement initial d'un engin de forage mobile (12). Un module de sélection (24) sélectionne un emplacement de destination de l'engin de forage (12). Un module d'établissement de corridor (26) établit un corridor entre l'emplacement initial de l'engin de forage (12) et son emplacement de destination, le corridor ayant une largeur sélectionnée. Une unité de traitement (28) réagit aux modules (18, 24 et 26) afin de sélectionner un emplacement de trou de chaque trou dans le corridor à forer séquentiellement par l'engin de forage (12) au fur et à mesure de son déplacement entre son emplacement initial et son emplacement de destination.
Patent CA-2902822-A1 (CA)
Inventor: ABU-AKEL FOUAD GERIES
IPC: A47B21/013
Filed: 2014-02-23
Abstract: A mobile computer workstation is disclosed and generally includes a base assembly, a power supply, a column assembly, a tray assembly, a monitor support assembly and a tray controller. The power supply can be housed in the base assembly. The column assembly is linearly extensible and extends upward from the base assembly. The column assembly can carry the tray assembly and monitor support assembly. The workstation can be optionally configured with a variety of storage solutions for any of a number of work environments and tasks. The tray assembly can house a computer that is integrated into the workstation. The tray controller provides a measure of security for the workstation by allowing access to the workstation and control over its features only by authorized users.
Patent CA-2904211-A1 (CA)
Title: Device and method for parallel microfluidic pressure-volume-temperature analysis
Inventor: JONES CHRISTOPHER MICHAEL
IPC: G01V11/00
Filed: 2013-04-18
Abstract: A microfluidic device and method is described to parallelize a pressure-volume-temperature ("PVT") analysis such that a portion of the pressure, temperature and volume analysis is performed separately from others. The resulting PVT data is then recombined statistically for a complete PVT analysis. The microfluidic device may also obtain compositional data of the fluid to perform an equation of state analysis or reservoir simulations.
Patent CA-2905993-A1 (CA)
Inventor: MOLLARD ALEXIS
IPC: A61P35/00
Filed: 2014-03-13
Abstract: Compounds having activity as inhibitors of ALK2 kinase and/or JAK2 kinase are disclosed. The compounds have the following structure (l), including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1 , R2, R3, R4, R5, R6, R7, R8, X, z and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Patent CA-2905997-A1 (CA)
Title: System and method for preparing, dispensing, and curing epoxy
Inventor: DUINEN KEITH VAN
IPC: B05C5/02
Filed: 2014-03-14
Abstract: A method for dispensing epoxy comprising the step of degassing an epoxy. The method further comprises the step of associating the epoxy with an epoxy injector comprising a dispensing end. The method further comprises the step of a computer receiving data representative of a selected container to receive the epoxy. The method further comprises the step of a computer determining a dispensing rate and a dispensing amount, based on the received data. The method further comprises the step of a computer causing the epoxy injector to dispense the determined dispensing amount of epoxy, via the dispensing end, at the determined dispensing rate. The method further comprises the step of a computer causing a dispensing arm, supporting the dispensing end, to retract the dispensing end while the epoxy injector is dispensing the epoxy. The method further comprises the step of curing the dispensed epoxy.
Patent CA-2906215-A1 (CA)
Title: Robust telemetry repeater network system and method
Inventor: VAN ZELM JOHN-PETER
IPC: G01V3/18
Filed: 2014-03-17
Abstract: A robust network telemetry repeater system exploits the repeater structure of data propagation and transmission and reception bidirectionality to increase network robustness. For example, multiple perceived receive attempts are created with no additional overhead. The system can be configured whereby nodes "hear" the transmissions of both adjacent and non- adjacent nodes forming implicit acknowledgement ("Acks"), and originating nodes can retransmit until implicit acknowledgments ("Acks") are "heard," indicating a successful link relay. Implicit acknowledgment can be applied to bidirectional networks, and bidirectional action can enable all nodes in the network to know the status of all other nodes.
Patent CA-2906448-A1 (CA)
Title: Virtual property reporting for automatic structure detection
Inventor: SCHULTZ STEPHEN L
IPC: G06F15/16
Filed: 2014-03-12
Abstract: A computer system comprises a processor capable of executing processor executable code operably coupled with a non-transitory computer medium storing processor executable code, which when executed by the processor causes the processor to: (a) receive a first signal over a computer network, the first signal indicative of a request for information about a target structure from a user; (b) in response to receiving the first signal, access a database including information about the target structure; and (c) transmit a second signal over the computer network indicative of a virtual property report for the target structure including at least one image of the target structure. The virtual property report may include information about a facet of the target structure facing a street, location of a main entrance of the target structure, location of a secondary entrance of the target structure, location of vehicle access to the target structure.
Patent CA-2907403-A1 (CA)
Title: Nitrile group-containing copolymer rubber, cross-linkable rubber composition, and cross-linked rubber
Inventor: KATADA ARINOBU
IPC: C08C19/00
Filed: 2014-03-20
Abstract: A nitrile group-containing copolymer rubber which has a hydroxyl group, carboxyl group, or carbon-carbon double bond at an end carbon atom or on a carbon atom which bonds with the end carbon atom is provided. The nitrile group-containing copolymer rubber of the present invention is preferably obtained by a metathesis reaction. According to the present invention, a nitrile group-containing copolymer rubber which is excellent in cross-linkability can be provided.
Patent CA-2908609-A1 (CA)
Inventor: COX JAMES C
IPC: G16H40/20
Filed: 2014-05-02
Abstract: Selon un premier mode de réalisation, l'invention concerne un système et un procédé qui permettent d'aider un médecin à prendre une décision de sortie de l'hôpital et qui consistent à rassembler des données-patient concernant le patient considéré qui est hospitalisé, à estimer une probabilité mathématique que le patient considéré sera réadmis à l'hôpital au cours d'une durée prédéterminée si le patient considéré était autorisé à quitter l'hôpital en ce jour, l'estimation de probabilité mathématique s'effectuant en fonction des données du patient rassemblées et des données-patient rassemblées parmi une population d'anciens patients de l'hôpital qui étaient sortis de l'hôpital précédemment et dont l'état de réadmission est connu, et à fournir des informations au médecin afin de l'aider à décider s'il convient ou non de laisser sortir le patient considéré, les informations étant fondées sur les résultats de l'estimation de probabilité mathématique.
Patent CA-2908653-A1 (CA)
Title: Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
Inventor: HARTMANN GUIDO
IPC: C07K16/22
Filed: 2014-04-25
Abstract: The invention provides anti-IGF-1R antibodies with abolished FcRn-binding and methods of using the same for the treatment of vascular eye diseases.
Patent CA-2911115-A1 (CA)
Title: Support de fixation de plateforme et batiment employant ledit support
Inventor: BOUCHARD JEAN-FRANCOIS
IPC: F16B1/00
Filed: 2015-11-02
Abstract: Il est décrit un support de raccordement de terrasse servant à attacher une terrasse à la fondation dun bâtiment. Le support de raccordement de terrasse comprend essentiellement les éléments suivants : une partie de raccordement pouvant sattacher à la fondation du bâtiment aux fins dutilisation; une partie de dégagement du bardage intégrée à la partie de raccordement qui saillit de celle-ci de façon perpendiculaire; un élément dencastrement de solive intégré à la partie de dégagement du bardage, ayant deux éléments espacés configurés pour encastrer une solive depuis le haut et séparés de la fondation par une distance de dégagement du bardage pendant lutilisation; une maille de renforcement intégrée à la partie de raccordement, laquelle maille saillit perpendiculairement de la partie de raccordement, longe la partie de dégagement du bardage et passe sous cette dernière et sétend vers le haut le long de la face externe de lélément dencastrement de solive pendant lutilisation.
Patent CA-2914394-A1 (CA)
Title: Apparatus for ball catching
Inventor: WEBSTER MATTHEW
IPC: E21B23/03
Filed: 2015-12-09
Abstract: There is provided an apparatus for ball catching and a system including the apparatus. The apparatus includes a ball-collection body, a chamber, a first blockage, a bypass line, a second blockage and a fluid directing mechanism. The apparatus is generally configured to collect balls while preventing the passage of the at least one ball during collection of balls from the chamber and to allow for removal of collected balls without disrupting the fluid flow. The system includes a frac tree configured to connect to a wellhead, a ball catcher, and downstream equipment.
Patent CA-2918237-A1 (CA)
Title: Audio decoder, audio encoder, method for providing at least four audio channel signals on the basis of an encoded representation, method for providing an encoded representation on the basis of at least four audio channel signals and computer program using a bandwidth extension
Inventor: DICK SASCHA
IPC: G10L19/18
Filed: 2014-07-14
Abstract: An audio decoder for providing at least four bandwidth-extended channel signals on the basis of an encoded representation is configured to provide a first downmix signal and a second downmix signal on the basis of a jointly encoded representation of the first downmix signal and the second downmix signal using a multi-channel decoding. The audio decoder is configured to provide at least a first (third) audio channel signal and a second (fourth) audio channel signal on the basis of the first (second) downmix signal using a multi-channel decoding. The audio decoder is configured to perform a multi-channel bandwidth extension on the basis of the first (second) audio channel signal and the third (fourth) audio channel signal, to obtain a first (second) bandwidth-extended channel signal and a third (fourth) bandwidth-extended channel signal. An audio encoder uses a related concept.
Patent CA-2922257-A1 (CA)
Inventor: NATIVIDAD ALEJANDRO V
IPC: H04L9/32
Filed: 2013-08-23
Abstract: A method for generating a changing authentication input or password generation and input for a user is provided for allowing access to a computing device such as a smartphone or computer or using the computing device to communicate over a network to a server. Using objects displayed in positions on a graphic display, and input strings of text or alphanumeric characters the user has related to each object, or are randomly assigned, a password can be generated by combining the input strings related to paired objects. The password can be varied easily for each access attempt by changing the objects displayed and/or the sequence.
Patent CA-2930089-A1 (CA)
Title: Fingolimod hydrochloride process
Inventor: GURJAR MUKUND KESHAV
IPC: C07C213/02
Filed: 2014-11-14
Abstract: A process for preparation of diethyl 2-acetamido-2-(4-octyl phenyl)ethyl malonate (III), a key intermediate of fingolimod hydrochloride comprising reaction of 2-(4- octylphenyl)ethyl iodide (IV) with diethyl acetamido malonate in presence of a base and an iodinating agent and in an organic solvent. The compound of formula (III) thus obtained provided fingolimod hydrochloride (la) having associated impurities below the regulatory limits.
Patent CA-2930389-A1 (CA)
Title: Whitefly ecdysone receptor nucleic acids, polypeptides, and uses thereof
Inventor: ZHANG JIANZHONG
IPC: C12P21/08
Filed: 2002-02-20
Abstract: The present invention relates to a novel isolated whitefly ecdysone receptor polypeptide. The invention also relates to an isolated nucleic acid encoding the whitefly ecdysone receptor polypeptide, to vectors comprising them and to their uses, in particular in methods for modulating gene expression in an ecdysone receptor-based gene expression modulation system and methods for identifying molecules that modulate whitefly ecdysone receptor activity.
Patent CA-2931719-A1 (CA)
Inventor: WENSEL MONTY
IPC: E04G23/06
Filed: 2016-05-31
Abstract: A system for raising and lowering a building relative to its foundation. A  plurality of permanently-installed lifting apparatuses engage the building or a building support structure and exert an upward force causing the building to be moved vertically relative to the foundation.
Patent CA-2934430-A1 (CA)
Title: Etiquettes de masse et methodes d'utilisation pour etiqueter les analytes
Inventor: THOMPSON ANDREW HUGIN
IPC: G01N33/68
Filed: 2014-12-18
Abstract: La présente invention concerne un procédé pour le marquage d'un ou plusieurs analytes dans un échantillon, le procédé comprenant : a) la mise en contact de l'échantillon avec un ou plusieurs réactifs lieurs bifonctionnels répondant à la formule générale Re1-L1-Re2, dans laquelle Re1 représente un premier groupe réactif, L1 représente une partie lieur et Re2 représente un second groupe réactif, Re1 réagissant avec un analyte pour former un analyte modifié; et b) la mise en contact de l'échantillon avec un ou plusieurs marqueurs de masse, Re2 du lieur bifonctionnel attaché à l'analyte réagissant avec un marqueur de masse pour former un analyte marqué, chaque marqueur de masse pouvant être associé à un analyte par spectrométrie de masse.
Patent CA-2934787-A1 (CA)
Title: Surface protective film
Inventor: KITAJIMA TOMOYUKI
IPC: C09J133/00
Filed: 2014-11-20
Abstract: A surface-protecting film according to the present invention is characterized by comprising a polyolefin base layer and an adhesive layer, wherein the adhesive layer contains at least a styrene-type elastomer, an acrylic adhesive agent and an adhesiveness-imparting agent, and the styrene-type elastomer, the acrylic adhesive agent and the adhesiveness-imparting agent are contained in the adhesive layer in amounts of 50 to 90% by mass inclusive, 1 to 40% by mass inclusive and 1 to 49% by mass inclusive, respectively, relative to the whole amount of the adhesive layer.
Patent CA-2935218-A1 (CA)
Inventor: MITTER BIRGIT
IPC: A01N63/20
Filed: 2014-12-24
Abstract: This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant.
Patent CA-2935611-A1 (CA)
Title: Method for extracting lignin
Inventor: VON SCHOULTZ SEBASTIAN
IPC: D21C1/10
Filed: 2015-01-09
Abstract: The invention relates to a method for removing lignin from lignocellulosic biomass. The method comprises feeding of lignocellulosic biomass and a first aqueous solution into a reactor vessel, the lignocellulosic biomass and the first aqueous solution forming a reaction mixture; reducing the pressure in the reactor vessel below 0.8 bar absolute pressure, preferably 0.5 bar absolute pressure, more preferably below 0.2 bar absolute pressure; keeping the reaction mixture in a predetermined extraction temperature, and adding at least one extraction chemical, such as base or acid, to the reaction vessel and extracting lignin from the biomass to the liquid phase of the reaction mixture.
Patent CA-2938637-A1 (CA)
Inventor: GROSS DAVE
IPC: G08G1/017
Filed: 2016-08-10
Abstract: A traffic preemption system including at least one of a vehicle and a driver identification means; a historical travel database; and a traffic signal preemption means.  The traffic signal preemption means is configured to preempt the normal action of traffic signals dependent upon the vehicle and/or the driver identified by the identification means and historical routes taken by the vehicle and/or the driver as determined in the historical travel database.
Patent CA-2942556-A1 (CA)
Inventor: LIU TIANJUN
IPC: C22C38/02
Filed: 2015-02-18
Abstract: La présente invention concerne un procédé de production d'une pièce d'acier forgé (200). Le procédé consiste à utiliser une billette d'acier qui peut être durcie de manière sélective à différents niveaux de dureté par variation de la vitesse de refroidissement à l'air. Le procédé consiste également à chauffer la billette d'acier à une température d'austénitisation de la billette d'acier. Le procédé consiste en outre à forger à chaud la billette d'acier pour former la partie d'acier (200) comprenant une première région (210) et une seconde région (220). Le procédé consiste de plus encore à refroidir sélectivement la pièce d'acier forgé à chaud (200) par refroidissement à l'air de la première région (210) à une première vitesse de refroidissement et par refroidissement à l'air de la seconde région (220) à une seconde vitesse de refroidissement qui est inférieure à la première vitesse de refroidissement.
Patent CA-2943130-A1 (CA)
Inventor: HOU BIN
IPC: F21V7/04
Filed: 2016-09-26
Abstract: An optical assembly for an LED light system with a LED light source is provided to control a light pattern of a light beam produced by the system, such as for spot or narrow flood light applications. The optical assembly includes a conical reflector with an interior reflective surface, a light diffuser and an optic holder. The light diffuser has an annular disk- shape with a central opening. The optic holder is mounted to a narrow open top of the reflector, and suspends the light diffuser inside of the reflector along an optical axis. The light diffuser is a cost- efficient optical element, which can be used in combination with the reflector to redistribute light in the system in order to soften a peripheral light area surrounding a center beam light area of the light pattern of the light beam, and reduce a harsh edge between the center beam and peripheral light areas.
Patent CA-2943198-A1 (CA)
Inventor: BLESSING DANIEL
IPC: C12N5/04
Filed: 2015-04-28
Abstract: The present disclosure pertains to novel cell cultivation and cell and/or cell-derived product production processes that have advantages over currently existing fermentation strategies. The processes and methods according to the present disclosure may be used for an efficient supply of highly viable and metabolically active eukaryotic cells for transient production platforms, as an alternative production process with advantages over currently applied processes (batch, fed-batch or perfusion strategies) and for generating metabolically highly active biomass for subsequent use for transient expression systems or infection by a virus or pseudovirus or in cell- free systems.
Patent CA-2950260-A1 (CA)
Inventor: MORRIS GABRIEL
IPC: E04F13/077
Filed: 2016-12-01
Abstract: A panel forming station has a frame, a pair of clamping devices and a pair of end forming devices. A panel is clamped between one clamping device and the frame.  The first forming device forms a first trimless end on the panel. The first forming device has a cutter bending blade and a roller that forms the first trimless end. The second clamping device clamps a panel. The second forming device has a cutter, a bending blade and a roller to form the second trimless end. A controller couples with the first and second clamping device and first and second end forming devices to control the panel's passage through the frame.
Patent CA-2950393-A1 (CA)
Inventor: SWAIN NIGEL ALAN
IPC: A61K31/433
Filed: 2015-05-29
Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I), or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3a, R3b and R4 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
Patent CA-2951408-A1 (CA)
Title: Methods and reagents for purification of proteins
Inventor: BLANK GREGORY SCOTT
IPC: B01D15/26
Filed: 2015-06-25
Abstract: The present disclosure provides compositions and methods for purifying a protein such as DNase using a chromatographic process. The methods include a single chromatographic step and the use of high concentration salt buffers. The present disclosure provides methods for purification of a protein from a sample comprising loading the sample onto a chromatography column and washing the column with at least one buffer having very high conductivity. In some embodiments, the wash buffer has a conductivity of about 50 mS/cm, about 60 mS/cm, about 70 mS/cm, about 80 mS/cm, or higher. In further embodiments, the protein is eluted from the column with an etution buffer following the wash with the very high conductivity buffer.
Patent CA-2951466-A1 (CA)
Title: Two-component coating compositions and coatings produced therefrom for improving erosion resistance
Inventor: HOHNHOLZ DIETER
IPC: C08G18/44
Filed: 2015-04-28
Abstract: The invention relates to a two-component coating composition comprising (1) a base component comprising (A) at least one polycarbonate diol, (B) at least one diamine that contains secondary amino groups and an aliphatic group (b1) between the nitrogen atoms of the amino groups, and (2) a hardener component comprising (C) at least one polyisocyanate-modified polyester having an isocyanate content of 4 to 15%. The invention also relates to a method for coating substrates by applying the coating composition as well as to the use thereof.