baber/WOPTO huggingface dataset:
Patent JP-2022123020-A (JP)
Title: Selective detection of bedbug
IPC: A61L2/04
Filed: 2022-06-14
Abstract: PROBLEM TO BE SOLVED: To provide detection, monitoring and control of insects including bedbug. 
     SOLUTION: There are disclosed a device, a system and a method for controlling pest. A harmful pest control device includes a sensor having a sensor cell and a controller. A surface of the sensor cell is covered with an agent which reacts to a target biochemical analyte which is excreted by the pest. The controller is coupled to the sensor, and receives sensor data indicating a speed of change of sensor mass detected on the surface of the sensor cell from the sensor cell, determines whether the speed of change of the sensor mass based on the received sensor data exceeds a predetermined threshold speed, and sends a pest detection alarm report to a server in response to determination that the speed of change exceeds the predetermined threshold speed. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2022,JPO&INPIT
Patent JP-2023103153-A (JP)
Title: Information processing device, information processing method and program thereof
Inventor: TSUJI SHUSUKE
IPC: G01D9/00
Filed: 2022-06-17
Abstract: To make it possible to measure a desired environmental value.SOLUTION: An information processing device comprises: a processor including a memory; a sensing part; an acquisition part using the sensing part to acquire a measured value according to an environment in which the information processing device is disposed; a logic storage part for storing at least any of a plurality of computational logics corresponding to a plurality of types of environmental values representing a state relating to the environment and a plurality of computational logics corresponding to a plurality of types of calculation methods of the environmental value; and a calculation part for calculating the environmental value from the measured value by the computational logic corresponding to a set type.SELECTED DRAWING: Figure 1
Patent JP-2022121581-A (JP)
Title: Semiconductor device
IPC: H01L21/28
Filed: 2022-06-29
Abstract: PROBLEM TO BE SOLVED: To provide a semiconductor device capable of reducing switching loss and resonance noise. 
     SOLUTION: A semiconductor device 81 includes: a semiconductor layer 15 including a trench 10; a field effect transistor structure 8 including a base region 28 and an emitter region 31 and formed adjacently to the trench 10; a floating region 9 formed with the same depth as the base region 28 in a region at an opposite side of the field effect transistor structure 8 with the trench 10 interposed therebetween; an insulator film 18 covering a wall surface of the trench 10; a first embedded electrode 19 disposed within the trench 10 so as to be opposed to the field effect transistor structure 8 with the insulator film 18 interposed therebetween; and a second embedded electrode 20 insulated from the first embedded electrode 19 and disposed within the trench 10 so as to be opposed to the floating region 9 with the insulator film 18 interposed therebetween. A curvature center of the base region 28 is positioned at a top face side of the semiconductor layer 15, and a curvature center of the floating region 9 is positioned at the top face side of the semiconductor layer 15. 
     SELECTED DRAWING: Figure 8 
     COPYRIGHT: (C)2022,JPO&INPIT
Patent JP-2024010801-A (JP)
Title: 液晶ポリエステル組成物及び成形体
IPC: C08L67/00
Filed: 2022-07-13
Abstract: 【課題】金型からの成形体の取り出し易さを表す離型性がより高められた液晶ポリエステル組成物、及びこれを含む成形体を提供する。【解決手段】本発明は、液晶ポリエステルと、特定の高分子量ポリエチレンと、を含有する液晶ポリエステル組成物を採用する。高分子量ポリエチレンの極限粘度は、１０ｄＬ／ｇ以上、１８ｄＬ／ｇ以下であり、高分子量ポリエチレンの体積中位径（ｄ５０）は、６５μｍ以下であり、高分子量ポリエチレンの含有量が、液晶ポリエステル１００質量部に対して０．１質量部以上、１．２質量部以下であることを特徴とする。【選択図】なし
Patent JP-2022132416-A (JP)
Title: Image forming apparatus
IPC: G03G21/00
Filed: 2022-07-13
Abstract: PROBLEM TO BE SOLVED: To provide an image forming apparatus that can reduce an image defect and can reduce leakage of toner. 
     SOLUTION: An image forming apparatus comprises: photoreceptors that each carry a toner image; transfer units that each transfer the toner image carried on the photoreceptor to a sheet; cleaning units that each recover a toner remaining on a peripheral surface of the photoreceptor after the toner images are transferred to the sheet by the transfer units; a first screw 32Y that conveys the toner recovered by the cleaning unit in an arrow A direction; a second screw 42 that conveys the toner delivered from the first screw 32Y in an arrow B direction intersecting the arrow A direction; a motor that drives the photoreceptors; a motor M2 that supplies a driving force to the first screw 32Y and second screw 42; a case 70 that accommodates the first screw 32Y and second screw 42; and a connection part 60 that is arranged inside the case 70 and connects to drive the first screw 32Y and second screw 42. 
     SELECTED DRAWING: Figure 3 
     COPYRIGHT: (C)2022,JPO&INPIT
Patent JP-2024011051-A (JP)
Title: 制振ブレース
IPC: E04H9/02
Filed: 2022-07-13
Abstract: 【課題】温度依存性が小さく、製造が簡単な制振ブレースを提供する。【解決手段】ダンパーユニット３０が軸部材に添わせて設けられた構造物用の制振ブレース１であって、構造物の骨組に一端部が接続された鋼製の第一軸部材１０と、第一軸部材１０の表面に沿って設置され一端部とは反対側の他端部が構造物の骨組に接続された鋼製の第二軸部材２０と、第一軸部材１０と第二軸部材２０との間に介設されたダンパーユニット３０とを備えている。ダンパーユニット３０は、高減衰ゴム３１と、高減衰ゴム３１の両面に固定された一対の鋼板３２とを備えて構成され、方の鋼板３２は２液アクリル樹脂系の構造用接着剤層を介して第一軸部材１０に接着接合され、他方の鋼板３２は２液アクリル樹脂系の構造用接着剤層を介して第二軸部材２０に接着接合されている。【選択図】図１
Patent JP-2024011063-A (JP)
Title: 送信装置、受信装置及びプログラム
IPC: H04L27/26
Filed: 2022-07-13
Abstract: 【課題】 TMCC情報の伝送特性を改善することを可能とする送信装置、受信装置及びプログラムを提供する。【解決手段】 送信装置は、部分受信帯域及び非部分受信帯域において、1以上の階層に属するデータキャリアシンボル及び伝送制御情報に対応する伝送制御キャリアシンボルを含む伝送フレームを送信する送信部と、前記伝送制御キャリアシンボルを前記データキャリアシンボルに対して増幅する電力調整部と、を備え、前記電力調整部は、前記データキャリアシンボルに対する前記伝送制御キャリアシンボルの増幅比として、前記部分受信帯域について第1増幅比を設定し、前記非部分受信帯域について第2増幅比を設定する。【選択図】図２
Patent JP-2024011535-A (JP)
Title: ポリプロピレン樹脂とシリコーンゴムの接合物及びその製造方法
IPC: C08J5/12
Filed: 2022-07-15
Abstract: 【課題】ポリプロピレン樹脂と付加硬化型シリコーンゴムとが強固に接合された接合物と、その製造方法との提供。【解決手段】乾式処理されたポリプロピレン樹脂と付加硬化型シリコーンゴムが、２種のプライマー組成物により接合された接合物であって、乾式処理されたポリプロピレン樹脂／第１のプライマー層／第２のプライマー層／付加硬化型シリコーンゴムの順で接合された接合物。第１のプライマー層：ケイ素原子に３－アミノプロピル基が結合したシラン化合物、及び、１分子中に１個以上のエポキシ基含有有機基を有するシラン化合物を含有する第１のプライマー組成物第２のプライマー層：１分子中にケイ素原子に結合したアルケニル基を２個以上有するオルガノポリシロキサンと、１分子中にヒドロシリル基を２個以上有するオルガノハイドロジェンポリシロキサンと、白金族金属触媒とを含む第２のプライマー組成物【選択図】なし
Patent JP-2024011547-A (JP)
Title: 配車管理装置及び配車管理方法
IPC: G08G1/123
Filed: 2022-07-15
Abstract: 【課題】移動体の配車までの時間を短縮する。 
【解決手段】配車管理装置１は、第１種別の第１移動体の空き状況と、第１移動体よりも乗客を乗せる機会が多い第２種別の第２移動体の空き状況とを示す状況データを記憶する記憶部１２と、移動体への乗車を希望するユーザが使用する情報端末２から、配車要求データを受信する端末通信部１３１と、端末通信部１３１が配車要求データを受信したときに、第１移動体に空きがあることを状況データが示している場合、第２移動体に空きがあるか否かによらず第１移動体に配車依頼データを送信し、第１移動体に空きがないことを状況データが示していることを条件として、第２移動体に配車依頼データを送信する移動体通信部１３２と、を有する。 
【選択図】図３
Patent JP-2024011624-A (JP)
Title: 山留壁の構造
IPC: E02D5/18
Filed: 2022-07-15
Abstract: 【課題】本設としての利用に供される山留壁の構造であって、山留壁が接合されるコンクリート製の地下構造物とを分離独立した設計による構築を可能とする山留壁の構造を提供すること。また、山留壁の地下構造物への接合に用いられるシアコネクタの山留壁への取り付け作業に要する労力及び時間を軽減すること。【解決手段】山留壁10の構造は、コンクリート製の地下構造物18aが構築される地下空間20を規定する壁面22を有する仮設のソイルセメント柱列壁12と、ソイルセメント柱列壁の柱列を構成する複数の柱16に固定され地下空間をソイルセメント柱列壁に沿って伸び、ソイルセメント柱列壁の壁面を覆う鋼製のプレート24と、プレートに固定され地下空間を水平に伸びる、ソイルセメント柱列壁と地下構造物とを接合するための複数のシアコネクタ26とを備える。【選択図】図１
Patent JP-2022169623-A (JP)
Title: Endless flexible belt for printing system
IPC: B41J2/01
Filed: 2022-08-09
Abstract: PROBLEM TO BE SOLVED: To provide a flexible belt for use in a printing system. 
     SOLUTION: The belt comprises an endless strip which, in use, travels along a continuous path. Formations are provided along sides of the strip, and are capable of engaging with lateral tracks to thereby place the belt under lateral tension, the lateral tracks further including a function of constraining the belt to follow the continuous path. 
     SELECTED DRAWING: Figure 6 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022163163-A (JP)
Title: Apparatus and methods for communicatively coupling field devices to controllers in process control system using distributed marshaling architecture
IPC: G05B19/042
Filed: 2022-08-10
Abstract: PROBLEM TO BE SOLVED: To provide an apparatus, a system, and a method for communicating data between a controller and a multiplicity of field devices operating in a process plant. 
     SOLUTION: The system includes distributed marshaling modules coupled by a head-end unit to I/O cards in communication with the controller. The distributed marshaling modules communicate with the field devices via respective electronic marshaling components converting signals between the field devices and the I/O cards. The distributed marshaling modules are coupled to the head-end unit by a ring communication architecture, such that the distributed marshaling modules may each be located relatively proximate to the field devices to which they are coupled. 
     SELECTED DRAWING: Figure 2A 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022145951-A (JP)
Title: Method for producing (4s)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile
IPC: A61P35/00
Filed: 2022-08-12
Abstract: PROBLEM TO BE SOLVED: To provide a new and improved method for preparation of (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile, and preparation and use of a crystal form. 
     SOLUTION: A method includes crystallizing a compound according to a formula in the figure out of an alcohol, preferably ethanol, then heating the resulting crystal paste to 50-80°C, and stirring it for 2-5 hours. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022163193-A (JP)
Title: Anti-human transferrin receptor antibody permeating blood-brain barrier
IPC: C07K16/28
Filed: 2022-08-16
Abstract: PROBLEM TO BE SOLVED: To provide means that can be used for modifying a substance biologically or pharmacologically active but not capable of permeating the blood-brain barrier, into the form capable of permeating it, and a modified substance obtained by using the means. 
     SOLUTION: The means is an anti-human transferrin receptor antibody and the modified substance is a molecular conjugate of a biologically active protein or a pharmacologically active low-molecular-weight compound and the anti-human transferrin receptor antibody. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022180357-A (JP)
Title: Nanospheres of SEC14-like proteins and cognate ligands
IPC: A61K47/62
Filed: 2022-08-22
Abstract: PROBLEM TO BE SOLVED: To provide nanospheres of SEC 14-like family of proteins and their cognate ligands, as well as methods of producing the same and uses of the nanospheres. 
     SOLUTION: The present invention provides a nanosphere comprising, preferably consisting of, an equal number of (i) a human SEC 14-like protein and (ii) a cognate ligand of the SEC 14-like protein. The equal number may be 3 to 60. The human SEC14-like protein may be selected from (a) α-tocopherol transfer protein (α-TTP); (b) Cellular retinaldehyde binding protein (CRALBP); (c) Clavesin1 (CLVS1); (d) Clavesin2 (CLVS2); and (e) α-tocopherol transfer protein like (TTPAL). 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023039943-A (JP)
Title: Adhesive-layer-equipped substrate, laminate, and coating composition
Inventor: ISEDA KAZUYA
IPC: C09D201/00
Filed: 2022-09-09
Abstract: To provide an adhesive-layer-equipped substrate, a coating composition and a laminate which have high wear resistance, adhesion, durability and weather resistance.SOLUTION: An adhesive-layer-equipped substrate comprises a substrate, and an adhesive layer disposed on the substrate. The adhesive layer contains polymer particles (A), an inorganic oxide (B), and a light-shielding agent (D). The light-shielding agent (D) contains an ultraviolet absorber. In elemental analysis with XPS on the adhesive layer surface in the adhesive-layer-equipped substrate, a metal (M) derived from an inorganic oxide is such that the M element concentration obtained from the M spectrum is 6 atom% or more.SELECTED DRAWING: None
Patent JP-2023091729-A (JP)
Title: Plate for analysis
Inventor: AIDA KEISUKE
IPC: C12M1/34
Filed: 2022-09-26
Abstract: To provide a plate for analysis capable of reducing a time required for a series of thermal cycles in which a temperature of a sample is raised and then lowered.SOLUTION: A plate 1 for analysis is plate-like and includes: a plate body 11 having a sample chamber 111b in which a sample is disposed therein, an introduction port 112b, a discharge port 113b, a flow passage 112d communicating with the sample chamber 111b and the introduction port 112b, and a flow passage 115a communicating with the sample chamber 111b and the discharge port 113b; an introduction port sealing member 12 for sealing the introduction port 112b in operation; and a discharge port sealing member 14 for sealing the discharge port 113b in operation. A width W11 in an X-axis direction of the sample chamber 111b is wider than a width W12 in a Z-axis direction of the sample chamber 111b.SELECTED DRAWING: Figure 2
Patent JP-2022174328-A (JP)
Title: Patterning method of energizing path-attached member and energizing path, and member change measurement method
IPC: G01L1/00
Filed: 2022-09-26
Abstract: PROBLEM TO BE SOLVED: To provide means which can objectively measure conditions of various members with a simple configuration, so as to achieve maintenance management of the whole building, determination of maintenance time, or specification of a building or its portion requiring preferential repair and to achieve a more excellent design than before. 
     SOLUTION: Energizing paths for measuring a change of a member as a measurement object are directly formed on the whole or a part of the member. The member includes engagement parts for connecting with a mating member at least at two positions. The energizing paths are provided between the engagement parts. 
     SELECTED DRAWING: Figure 3 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023001163-A (JP)
Title: Injection molded article and method for producing the same
IPC: C08F216/14
Filed: 2022-10-25
Abstract: PROBLEM TO BE SOLVED: To provide an injection molded article which is excellent in physical properties such as low water vapor permeability, low chemical liquid permeability, wear resistance, mechanical strength and rigidity at a high temperature and is significantly improved in ozone resistance. 
     SOLUTION: There is provided an injection molded article which contains a copolymer containing a tetrafluoroethylene unit and a fluoro (alkyl vinyl ether) unit, wherein the content of the fluoro (alkyl vinyl ether) unit is 4.7 to 7.0 mass% based on the total monomer units, the melt flow rate at 372°C is 11.0 to 22.0 g/10 min, the melting point of the copolymer is 296 to 305°C and the amount of fluoride ions eluted from the injection molded article into water is 7500 μg/m 2  or less. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023014104-A (JP)
Title: Operation system, processing system, operation method, and program
IPC: G06F3/0481
Filed: 2022-11-04
Abstract: PROBLEM TO BE SOLVED: To provide an operation system configured to reduce the burden on a user, a processing system, an operation method, and a program. 
     SOLUTION: An operation system includes an acquisition unit, an arithmetic operation unit, and a generation unit. The acquisition unit acquires an output from a first device to be operated. The arithmetic operation unit generates an operation instruction on the basis of a result of acquiring the output and an operation file prepared in advance. The generation unit generates an operation signal corresponding to the first device, on the basis of the operation instruction, and transmits the signal to the first device. The operation file includes a first file including a generation operation for generating the operation instruction, and a second file which is referred when the generation operation is executed and includes information to be used for identifying the output and generating the operation signal. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023095782-A (JP)
Title: Multilayer electronic component and method of manufacturing the same
Inventor: SONG YOUNG AH
IPC: H01G4/232
Filed: 2022-11-11
Abstract: To provide a compact and high-capacity multilayer electronic component with improved corner coverage, plating coverage, and Si agglomeration, having high reliability.SOLUTION: The multilayer electronic component includes: a body 110 including a plurality of dielectric layers 111 and internal electrodes 121, 122 arranged to oppose each other with the dielectric layers interposed therebetween; external electrodes 131, 132 that are connected to the internal electrodes and include a plurality of conductive particles. The plurality of conductive particles includes first conductive particles. The first conductive particles are plate-shaped conductive particles with a coating layer formed on a surface thereof. The coating layer includes Si, and the Si content is 0.3 at% or more and 2.0 at% or less with respect to the plate-shaped conductive particles.SELECTED DRAWING: Figure 2
Patent JP-2023083223-A (JP)
Title: Composition for preventing, improving or alleviating symptom relating to qi deficiency and/or blood deficiency
Inventor: SASAKI KATSUNORI
IPC: A61P3/02
Filed: 2022-11-16
Abstract: To provide a composition containing a crude drug component for preventing, improving or alleviating a symptom relating to qi deficiency and/or blood deficiency.SOLUTION: A composition contains a following component (1), component (2), component (3) and component (4), as active ingredients: the component (1): at least one crude drug selected from a group consisting of honey-fried licorice decoction, licorice, dioscorea rhizome, jujube, saccharum granorum and ginseng; the component (2): at least one crude drug selected from a group consisting of jiang huang, longan, curcuma zedoaria, mucuna birdwoodiana, luffa, sparganium simplex Hudson, safflower and artemisia anomala; the component (3): at least one crude drug selected from a group consisting of tea leaf, peppermint, mulberry leaf, chrysanthemum and Glycinemax Mer; and component (4): at least two crude drugs selected from a group consisting of citrus unshiu peel, bean of Psoralea corylifolia, garcinia esculenta, piper longum, cinnamomum cassia, perilla, ginger, coriander, welsh onion, ziziphus jujuba, thujae semen, plantago seeds, plantago asiatica, coix seed, cone silk, burning bush, winter melon, common knotgrass, clechoma hederacea, cinnamon, zingiber siccatum, fennel, zanthoxylum fruit, pepper, siberian ginseng, and mugwort.SELECTED DRAWING: None
Patent JP-2023036591-A (JP)
Title: Method for coating printable lithium composition for forming battery electrode
IPC: H01M4/38
Filed: 2022-11-28
Abstract: PROBLEM TO BE SOLVED: To provide a method for depositing lithium on a substrate to form an electrode. 
     SOLUTION: A method includes a step of coating a substrate with a printable lithium composition which contains: lithium metal powder; a polymer binder compatible with the lithium metal powder; a rheology modifier compatible with the lithium metal powder; and a solvent compatible with the lithium metal powder and with the polymer binder. The printable lithium composition contains, on a solution basis, 5-50% of the lithium metal powder, 0.1-20% of the polymer binder, 0.1-30% of the rheology modifier, and 50-95% of the solvent. The solvent is a non-polar solvent, and the rheology modifier does not contain alumina. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023017113-A (JP)
Title: game machine
IPC: A63F7/02
Filed: 2022-12-12
Abstract: PROBLEM TO BE SOLVED: To provide a game machine capable of executing appropriate processing according to a situation when power is interrupted. 
     SOLUTION: A game machine includes: displacement means capable of performing displacement to a first position and a second position; state determination means capable of determining a state of the displacement means; and processing execution means for, when power is supplied to the game machine, executing first processing when a state is determined to be a first state by the state determination means, and for executing second processing when a state is determined to be a second state. 
     SELECTED DRAWING: Figure 611 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023029391-A (JP)
Title: Manufacturing method of vibration device
IPC: H01L23/02
Filed: 2022-12-20
Abstract: PROBLEM TO BE SOLVED: To provide a vibration device in which stress is hardly applied to a joint region between a base substrate and a lid and which has excellent mechanical strength, a manufacturing method of the vibration device, a vibration module, an electronic device, and a moving body. 
     SOLUTION: A vibration device includes: a base substrate including a main surface, a side surface, and an inclined surface connecting the main surface and the side surface and inclined with respect to the main surface and the side surface; a vibrating element arranged on the main surface side of the base substrate; and a lid bonded to the main surface of the base substrate so as to accommodate the vibration element between the lid and the base substrate, in which a bonding region where the base substrate and the lid are bonded is positioned on the inner side than the outer edge of the main surface. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023029449-A (JP)
Title: Barrier film for electronic devices
IPC: B32B9/00
Filed: 2022-12-23
Abstract: PROBLEM TO BE SOLVED: To provide a laminate including a barrier film for electronic devices that exhibits an excellent water barrier property and can maintain the property for a long time. 
     SOLUTION: A laminate includes desiccant sheets, and a barrier film for electronic devices that is sandwiched between the desiccant sheets in a removable manner. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023030136-A (JP)
Title: Aerosol delivery device including housing and coupler
IPC: A24F40/40
Filed: 2022-12-23
Abstract: PROBLEM TO BE SOLVED: To provide an aerosol delivery device which may be characterized as electronic cigarettes. 
     SOLUTION: The aerosol delivery device may include a control body and a cartridge including an atomizer and a reservoir configured to contain an aerosol precursor composition. The control body may include a housing defining an electrical power source cavity that extends along a first longitudinal axis and is configured to receive an electrical power source. The control body may additionally include a coupler configured to engage the cartridge including the aerosol precursor composition such that the cartridge extends along a second longitudinal axis. The first longitudinal axis and the second longitudinal axis may be non-coaxial and oriented substantially parallel to one another. 
     SELECTED DRAWING: Figure 17 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022542116-A (JP)
Title: 検知された身体動作に基づいて植込み型医療デバイスを操作するためのシステムおよび方法
IPC: A61B5/11
Filed: 2020-07-24
Abstract: 患者によって意図的に実行される指定された身体動作の検知された発生に応答して、植込み型医療デバイスの動作を制御するシステムおよび／または方法。【選択図】図１
Patent JP-2022546559-A (JP)
Title: 櫛形ポリマーおよびブロックコポリマーで安定化された、核酸および他の可溶性親水性化合物を封入するナノ粒子
IPC: A61K47/36
Filed: 2020-09-02
Abstract: 水溶性材料を含有する親水性コアおよび疎水性シェルを有するナノ粒子を形成するための沈殿経路が記載される。このプロセスは、より極性の高い領域およびより非極性の領域から構成される安定化ポリマーを必要とする。これらの領域は、直鎖状ブロックコポリマーとして配置されるか、または直鎖状もしくは分岐鎖状の極性骨格と、非極性側鎖もしくは置換基とを有する櫛形ポリマーとして配置され得る。ＤＮＡおよびＲＮＡを含む核酸、ならびにタンパク質、ペプチド、および多糖、または組み合わせを、ナノ粒子コア中に封入できる。核酸の封入は、塩基で酸を部分的または完全に中和して、プロセス溶媒流における核酸の溶解度を高めることを必要とし得る。結果として得られるナノ粒子のコアまたはシェルを架橋できる。ナノ粒子は、水中に入れるために追加のポリマーでコーティングされてもよいし、処理してマイクロ粒子またはより大きなモノリスにされてもよい。
Patent JP-2022549102-A (JP)
Title: 創傷治癒および／または瘢痕修復の促進の有効性を有する皮膚局所用組成物
IPC: A61K36/718
Filed: 2020-07-16
Abstract: 本発明は、創傷治癒および／または瘢痕修復の促進の効果を有する皮膚局所用組成物であって、（Ａ）濃縮カバノキ樹液、ならびに（Ｂ）ワレモコウ根抽出物、オウレン根抽出物、ムラサキ抽出物、アラントイン、丹参抽出物、ゲンゲ抽出物、パール粉末およびアシアチコシドから選択される１つまたは複数の活性物質を含み、濃縮カバノキ樹液が約１．２～６倍、好ましくは約１．５～５倍、より好ましくは約１．５～３倍の濃縮度を有する、皮膚局所用組成物に関する。