Patent SG-11201809752V-A (SG)
Title: Amide-substituted pyridinyltriazole derivatives and uses thereof
Inventor: COLLIN-KRÖPELIN MARIE-PIERRE
IPC: C07D401/14
Filed: 2017-05-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111101111 11 11111111111111 010111011101111111111111111111111101111111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2017/191102 Al 09 November 2017 (09.11.2017) W I P0 I P C T (51) International Patent Classification: SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, CO7D 401/14 (2006.01) A61P 9/00 (2006.01) TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. A61K 31/4439 (2006.01) (84) Designated States (unless otherwise indicated, for every (21) International Application Number: kind of regional protection available): ARIPO (BW, GH, PCT/EP2017/060356 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (22) International Filing Date: UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 02 May 2017 (02.05.2017) TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (25) Filing Language: English MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (26) Publication Language: English TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (30) Priority Data: 16168165.5 03 May 2016 (03.05.2016) EP Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a (71) Applicant: BAYER PHARMA AKTIENGESEL- patent (Rule 4.1700) LSCHAFT [DE/DE]; Milllerstr. 178, 13353 Berlin (DE). Published: (72) Inventors: COLLIN, Marie-Pierre; Katernberger Schul- — with international search report (Art. 21(3)) weg 52, 42113 Wuppertal (DE). KOLKHOF, Peter; _ Falkenberg 121, 42113 Wuppertal (DE). NEUBAUER, Thomas; Kaiser-Wilhelm-Allee 12, 42117 Wuppertal (DE). FURSTNER, Chantal; Arnoldstr. 33, 45478 Mill- - heim/Ruhr (DE). POOK, Elisabeth; Im Lehmbruch 24, = 42109 Wuppertal (DE). WITTWER, Matthias, Beat; Griinewalder Berg 41, 42105 Wuppertal (DE). LUSTIG, = Klemens; Falkenberg 159, 42113 Wuppertal (DE). BUCH- — = MULLER, Anja; Baderweg 72a, 45259 Essen (DE). = TINEL, Hanna; In der Beek 16, 42113 Wuppertal = (DE). DROBNER, Karoline; Auf der Ni111 2, 42109 = Wuppertal (DE). MONDRITZKI, Thomas; Von-Hum- boldt-Strasse 34a, 42549 Velbert (DE). SCHIRMER, Heiko; Dingshauser StraBe 51a, 42655 Solingen (DE). — KRETSCHMER, Axel; Am Acker 23, 42113 Wupper- tal (DE). SCHMECK, Carsten; Carl-Friedrich-Goerdel- =_ er-StraBe 24, 45472 Millheim (DE). WASNAIRE, Pierre; = Am Botanischen Garten 41, 40225 Diisseldorf (DE). CER- = NECKA, Hana; Augustastrasse 85, 42119 Wuppertal = (DE). Agent: BIP PATENTS; Alfred-Nobel-Str. 10, 40789 Mon- (74) = heim am Rhein NRW (DE). = Designated States (unless otherwise indicated, for every (81) = kind of national protection available): AE, AG, AL, AM, — AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, = _ 1-1 0 el 1-1 1-1 0\ 1-1 (54) Title: AMIDE-SUBSTITUTED PYRIDINYLTRIAZOLE DERIVATIVES AND USES THEREOF IN ,-1 (57) : The present invention relates to novel 5-(carboxamide)-1-pyridiny1-1,2,4-triazole derivatives, to processes for the prepa- CZ ration of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compo- \" sitions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular 0 diseases.