baber/WOPTO huggingface dataset:
Patent NZ-594567-A (NZ)
Title: 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
Inventor: FUCHS KLAUS
IPC: A61K31/4162
Filed: 2010-03-26
Abstract: The disclosure relates to a family of 1,6-disubstituted pyrazolopyrimidinones of formula (I). Hc is a tetrahydropyranyl- group and R1 is the group V-W-*, wherein V and W may be an aryl group or a heteroaryl group and are chosen independently. These various groups may be further substituted. R2 and R3 are chosen from hydrogen, fluorine or fluorinated alkyl groups. These compounds inhibit PDE9 and pharmaceutical compositions and medicaments using these compounds are also disclosed. These compositions and medicaments may be used in the treatment of conditions concerning deficits in perception, concentration, learning or memory, including Alzheimer's disease and the cognitive impairment associated with Alzheimer's disease.
Patent NZ-595196-A (NZ)
Title: Peptide-based compounds for enzyme inhibition
Inventor: ZHOU HAN-JIE
IPC: A61K38/55
Filed: 2006-11-09
Abstract: ABSTRACT - 595196 Peptide-based compounds of formula (I) which include heteroatom-containing, three membered rings are disclosed, wherein the variables are as defined in the specification. These compounds efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases associated with the proteasome. These peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, these peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation. Oral administration of these peptide-based proteasome inhibitors is possible due to their bioavailability profiles. These compounds are particularly suitable for treating septic shock, parasitic infections, conditions associated with acidosis, pulmonary conditions, nerve injury, hepatic failure, ischemic condition or reperfusion injury selected from the group consisting of: acute coronary syndrome, arterial occlusive disease, atherosclerosis, infarctions, heart failure, pancreatitis, myocardial hypertrophy, stenosis, and restenosis, and for the inhibition of cell adhesion.
Patent NZ-598050-A (NZ)
Title: Azetidinone compounds and medical use thereof
Inventor: BAI HUA
IPC: A61K31/397
Filed: 2010-08-09
Abstract: Disclosed are azetidinone compounds and medical use thereof are provided by the present invention. More particularly, azetidinone compounds, shown as formula (I), wherein R1, R2, R3, R4, R5, R6 are defined in description, and preparation methods thereof are provided by the present invention. The compounds of the present invention can reduce the levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) in plasma, and can be used as medicaments for reducing cholesterol in blood. Therefore the compounds of the present invention can be used to treat or prevent diseases of atherosclerosis, cacergasia of blood vessel, cardiac failure, coronary artery disease, angiocardiopathy, myocardial, angina, hyperlipoidemia and hypercholesteremia and the like. Preparation method of compounds of formula (I) and intermediate compounds are also provided by the present invention
Patent NZ-598622-A (NZ)
Title: Methods for iontophoretically treating nausea and migraine
Inventor: SEBREE TERRI B
IPC: A01N43/76
Filed: 2010-08-10
Abstract: 598622 Disclosed is the use of an effective amount of a trip tan compound in the manufacture of a medicament for treating nausea in a subject suffering from a migraine, wherein the triptan compound is formulated for iontophoretic administration, such that the nausea is treated without cardiovascular side effects.
Patent NZ-598971-A (NZ)
Title: Granulated compositions and their use
Inventor: VOYCE WARWICK GEORGE
IPC: A23L33/00
Filed: 2009-03-25
Abstract: ABSTRACT - 598971 The disclosure relates to dietary supplement granules suitable for animals, each granule being a granulation of consistent mix ratio of at least three types of particle, the particles being: (i) particles of at least one particulate source of calcium not in the zero oxidation state and in a nutritionally available form ("calcium particles"), (ii) particles of at least one particulate source of magnesium not in the zero oxidation state and in a nutritionally available form ("magnesium particles"), and (iii) particles of at least one particulate source of sodium not in the zero oxidation state and in a nutritionally available form ("sodium particles"); wherein the calcium particles when expressed as CaCO3, irrespective of whether any or all of the calcium particles are of that form, comprise from 50 to 90% w/w of the granules, the magnesium particles when expressed as magnesium oxide, irrespective of whether any or all of the magnesium particles are of that form, comprise at least 5% w/w of the granules and less than the % w/w of the calcium particles, and the sodium particles when expressed as sodium chloride, irrespective of whether any or all of the sodium particles are of that form, comprise from 5 to 30% w/w of the granules; and wherein the particles of each granule are of varied size within each particle type and/or between particle types; and wherein each granule, to the extent it has a moisture content, it is at a moisture content less than that at which granulation has occurred; and wherein optionally each granule can include one or more other inclusions; and wherein the granules preferably are less than 8mm in size.
Patent NZ-599340-A (NZ)
Title: Fischer-Tropsch synthesis for producing hydrocarbons using a catalyst with specific dopant levels
Inventor: VISAGIE JACOBUS LUCAS
IPC: B01J23/75
Filed: 2010-09-23
Abstract: ABSTRACT - 599340 The disclosure relates to a process for producing hydrocarbons and, optionally, oxygenates of hydrocarbons, which process includes contacting a synthesis gas comprising hydrogen, carbon monoxide and N-containing contaminants selected from the group consisting of HCN, NH3, NO, RxNH3-x where R is an organic group and x is 1, 2 or 3, with R being the same or different when x is 2 or 3, R1-CN where R1 is an organic group, and heterocyclic compounds containing at least one nitrogen atom as a ring member of a heterocyclic ring of the heterocyclic compound, with the N-containing contaminants constituting, in total, at least 100vppb but less than 1,000,000vppb of the synthesis gas, at a temperature of at least 180°C and a pressure of at least 10 bar(a), with a particulate supported Fischer-Tropsch synthesis catalyst which comprises a catalyst support, Co in catalytically active form supported on the catalyst support, and a dopant selected from the group consisting of platinum (Pt), palladium (Pd), ruthenium (Ru), rhenium (Re) and a mixture of two or more thereof at a dopant level expressed by formula 1: where w is expressed as g Ru/g Co, and w < 0.019g Ru/g Co; x is expressed as g Pd/g Co; y is expressed as g Pt/g Co; z is expressed as g Re/g Co, and z < 0.005g Re/g Co; and 0?a<1, to obtain hydrocarbons and, optionally, oxygenates of hydrocarbons, by means of Fischer-Tropsch synthesis reaction of the hydrogen with the carbon monoxide.
Patent NZ-602759-A (NZ)
Title: Air compressor system and method of operation
Inventor: TANNER SIMO
IPC: F04B49/02
Filed: 2011-04-19
Abstract: A method of controlling an air compressor system (100) is disclosed. The method comprises measuring (16D) a working air pressure in or at an outlet of the air compressor (20) and adjusting an output control (12) based on the measured working air pressure when the working air is turned on. When the working air is turned off the air pressure is measured (16C) at a receiver (34), which stores compressed air, and the output control (12) is then adjusted based on the measured reservoir air pressure.
Patent NZ-611303-A (NZ)
Title: Recycled textile layer
Inventor: COOPER JASON IAN
IPC: D01G11/00
Filed: 2012-08-16
Abstract: Disclosed is a method of making a carpet backing layer. The method comprising the steps of passing used carpet through a disintegrator to yield target fibres and latex waste in an airborne mix, separating these in airborne stages and feeding the target fibres to a non-woven layer building machine. The method is advantageous in producing a non-woven (i.e. felted) carpet backing that does not require crushing/melting of recycled fibres into new fibres for subsequent creation of new woven layers.
Patent NZ-611879-A (NZ)
Title: Container panel improvements
Inventor: REES MICHAEL
IPC: B65D25/02
Filed: 2011-12-08
Abstract: 611879 A gate or panel for a storage container is disclosed. The design of the gates eliminates the need for screws to retain the infill or liner panel. Each gate or panel includes a rectangular or square infill panel (40) having an inner face and an outer face. An outer perimeter frame (10) is adjacent to the outer face of the infill panel and an infill panel attachment member (20) attached to and extending along at least a pair of opposing margins of the gate. Each infill panel attachment member has an infill panel retaining flange (30) which extends in a plane parallel to an inner face of the perimeter frame so that the infill panel is retained between the retaining flanges and an inner face of the outer perimeter frame.
Patent NZ-623852-A (NZ)
Title: Wire feed motor speed control
Inventor: PUTNAM GEOFFREY H
IPC: B23K9/12
Filed: 2012-10-12
Abstract: A system and a method are provided for improved run-in control during a start of a welding process. The system includes a power circuit generates welding output power. A control circuit in communication with the power circuit controls the output power. The control circuit receives a selection of a wire feed speed setting representing a wire feed speed. The control circuit receives a selection of a run-in percentage of the wire feed speed. The control circuit determines an effective run-in percentage that is equal to the run-in percentage plus an extra percentage.
Patent NZ-627043-A (NZ)
Title: Herherbicidal compositions for pastures
Inventor: MOLLOY CHRISTOPHER
IPC: A01N41/10
Filed: 2013-07-19
Abstract: Disclosed are synergistic herbicidal compositions comprising the active ingredients bentazone (3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide) and flumetsulam (2′,6′-difluoro-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonanilide) in ratios of from about 10:1 to about 200:1. Also disclosed are methods of preparing the formulations and a method of controlling weeds in agricultural crops, in particular pasture and fodder species, leguminous vegetable crops, seed crops and turf, all of which have differing herbicide tolerances.
Patent NZ-629427-A (NZ)
Title: Methods and compositions for treating huntington’s disease
Inventor: MILLER JEFFREY C
IPC: C12Q1/68
Filed: 2013-02-28
Abstract: Disclosed is a non-naturally occurring zinc finger protein that binds to an Htt gene, the zinc finger protein comprising 4, 5 or 6 zinc finger domains ordered F1 to F4, F1 to F5 and F1 to F6, wherein the zinc finger protein comprises one- or two-finger domain at positions F2 or F2 and F3, the one- or two-finger domains comprising the recognition helix regions sequences in F2 or F2 and F3 as shown in a single row of Table 2C and further wherein if the recognition helix of the one-finger domain at position F2 comprises QSSDLRR (SEQ ID NO:6) the recognition helix binds to GCA. Also disclosed is the use of such proteins is the preparation of a medicament for the treatment of Huntington’s Diseases.
Patent NZ-702254-A (NZ)
Title: 5-amino[1,4]thiazines as bace 1 inhibitors
Inventor: HILPERT HANS
IPC: C07D417/12
Filed: 2013-05-21
Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer’s disease.
Patent NZ-706279-A (NZ)
Title: Windscreen installation apparatus and method
Inventor: DAVIES CHRISTOPHER
IPC: B62D65/06
Filed: 2011-11-02
Abstract: Apparatus for use in handling windscreens is disclosed. The apparatus may be used to install windscreens in a vehicle. The apparatus includes a windscreen anchor assembly (2) comprising a windscreen anchor device and a support arm (16) extending away from the windscreen anchor device. A mount assembly (3) is provided for supporting the windscreen anchor assembly (2). The mount assembly (3) includes a mount yoke (11) for engaging with the support arm (16) such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure (11). Additionally, the support arm is able to be dismantled into more than one piece for stowage, the anchor device and a dismantled arm part being provided with means for attaching to one another.
Patent NZ-709731-A (NZ)
Title: Imaging apparatus with scene adaptive auto exposure compensation
Inventor: SUN GUOQIAN
IPC: H04N5/351
Filed: 2013-01-28
Abstract: A method adjusts an auto exposure target in an auto-exposure operation on a sequence of images, such as a sequence of infrared images. The method comprises: obtaining a histogram of at least one of the images; applying a weighted histogram table to the histogram to obtain weighted histogram bins wherein at least some bins in the histogram containing saturated pixels are assigned a higher weighting value and at least some bins in the histogram containing unsaturated pixels are assigned a lower weighting value, and summing the weighted histogram bins to obtain a saturation score and decreasing an auto exposure target for an auto exposure operation when the saturation score exceeds a first threshold value, and increasing the auto-exposure target when the saturation score is below the first threshold value and the image is underexposed.
Patent NZ-713357-A (NZ)
Title: Antimicrobial compounds and methods of making and using the same
Inventor: BHATTACHARJEE ASHOKE
IPC: C07D251/30
Filed: 2010-10-15
Abstract: The preparation of antimicrobial ureido-pyrimidinone derivatives of Formula Ia, by reacting a amino-pyrimidinone derivative precursor with a isocyanate derivative. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.
Patent NZ-714615-A (NZ)
Title: Tissue sampler
Inventor: MICHAEL STUART GARDNER
IPC: G01N1/08
Filed: 2013-10-18
Abstract: A tissue sampler 1 which includes a storage tube holder adapted in use to accommodate a storage tube for receiving a tissue sample, a magazine housing 230 adapted in use to accommodate a movable collecting device magazine 240 having a plurality of chambers, a cutting region between the tube holder and the magazine housing to accommodate an item from which the tissue sample is to be taken and an actuating means adapted to cause the movement of the collecting device 241 from its chamber, through the item to cut a tissue sample from the item, and into a first end of the storage tube 500.The collecting device which is held within one or more of the chambers of the collecting device magazine comprises a punch and a plunger. The plunger comprises an RFID tag enclosed within it. The plunger is located within a centrally located bore of the punch and able to slide within the bore of the punch.
Patent NZ-715154-A (NZ)
Title: Means for use in measuring dry matter content
Inventor: COLIN BRUCE MCFADZEAN
IPC: G01B5/06
Filed: 2015-12-14
Abstract: The invention relates to the field of measuring dry matter content of pasture. It is known to calculate the dry matter content of pasture by walking over a field and taking manual readings with a rising plate meter. This can be a slow and less than efficient procedure. In its preferred embodiment the invention comprises a meter for use in determining the dry matter content of pasture in a relatively efficient manner. The meter has a wheel 2, a planar rigid skid 3, and a weight or other means for applying a downward pressure to the plate. When the meter is in use it is coupled to and moved by a motor vehicle or other carrier over a field with the wheel 2 rolling along the ground and the skid 3 sliding over pasture. The wheel is spring loaded to help keep it in contact with the ground. A controller causes the meter to take multiple readings indicative of the distance between the ground and the skid, and these are used for determining the dry matter content of the pasture.
Patent NZ-721632-A (NZ)
Title: A chemical indicator device
Inventor: FUGERE NICOLE A
IPC: G01N30/74
Filed: 2013-06-28
Abstract: The invention relates to a chemical indicator device for providing a simple, portable, low cost device for detecting the presence of a chemical indicator in a reaction vessel. The chemical indicator device comprises a controller, a plurality of heat blocks (58) located on the opposite sides of a test sample container, and a housing. The heater blocks (58) are operatively coupled to the controller, and the housing includes a plurality of wells (34), each well of the plurality of wells configured to receive a sample container such that during use, a first side of a first sample container disposed in a first well of the plurality of wells is in proximity of a first heat block of the plurality of heat blocks and a second side, opposite the first side, of the first sample container is in proximity of a second heat block of the plurality of heat blocks, the controller configured for, during use, heating the first heat block to a first temperature and the second heat block to a second temperature, the first temperature different than the second temperature, such that a convection current is created between the first side and the second side of the first sample container within a sample disposed in the first sample container.
Patent NZ-733050-A (NZ)
Title: Processing biomass with irradiation
Inventor: MEDOFF MARSHALL
IPC: A23K10/12
Filed: 2009-04-28
Abstract: A method for producing a hydrocarbon material, the method comprising irradiating a biomass material with electron beam radiation dose of about 10 Mrad to 150 Mrad from one or more electron beam devices, saccharifying the irradiated biomass with an enzyme or a microorganism to produce a low molecular weight sugar, and converting the low molecular weight sugar to a hydrocarbon material.
Patent NZ-735530-A (NZ)
Title: Method and apparatus for treating iron-containing raw material using bath smelting furnace
Inventor: QI TAO
IPC: C21B11/08
Filed: 2017-09-21
Abstract: The present invention relates to method and apparatus for treating iron-containing raw material using a bath smelting furnace. The method comprising: providing an iron-containing raw material, wherein the iron-containing raw material further comprises vanadium and titanium; mixing the iron-containing raw material with a reducing agent to provide a mixture with a mass ratio of the iron-containing raw material to the reducing agent of 100:(20-60), wherein the reducing agent is one or more items selected from the group consisting of anthracite, bitumite and a lignite; adding the mixture into a bath smelting furnace; blowing enriched oxygen into a bath of the bath smelting furnace; smelting at a temperature of 1200-1600 ºC to obtain iron and slag; conducting casting or steel making using the iron; and conducting a valuable component extraction process using the slag.
Patent NZ-737725-A (NZ)
Title: Crystalline forms of a bruton’s tyrosine kinase inhibitor
Inventor: PURRO NORBERT
IPC: A61P35/00
Filed: 2013-06-03
Abstract: Disclosed herein is a crystalline Form C of 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, wherein the crystalline form has an X-ray powder diffraction (XRPD) pattern comprising 2-Theta peaks at about 7.0°, about 14.0°, about 15.7°, about 18.2°, about 19.1°, about 19.5°, about 20.3°, about 22.1°, and about 22.9°. Also disclosed is a crystalline Form C of 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, wherein the crystalline form has a differential scanning calorimetry (DSC) thermogram having an endotherm having an onset at about 134 °C to about 135 °C with a peak at about 137 °C to about 139 °C. Further disclosed are pharmaceutical formulations and medical uses of crystalline Form C.
Patent NZ-739720-A (NZ)
Title: Methods and kits for the detection of powdery mildew
Inventor: DUBOURNET PATRICE
IPC: C12Q1/68
Filed: 2016-07-08
Abstract: The present invention relates to means, methods and kits for the specific detection of the causing agent of powdery mildew on grapes, the fungus Erysiphe necator. More specifically, the methods according to the invention are quantitative methods based on quantitative Polymerase Chain Reaction. Primers and probes are used that are specific to the intergenic transcribed spacer (ITS) region of the fungus.
Patent NZ-741995-A (NZ)
Title: Embolisation systems
Inventor: ALLEN WAYNE
IPC: A61B17/12
Filed: 2014-03-14
Abstract: An embolisation device for promoting clot formation in a lumen comprising a stem and a plurality of flexible bristles extending outwardly from the stem. The bristles have a contracted delivery configuration and a deployed configuration in which the bristles extend generally radially outwardly from the stem to anchor the device in a lumen. The embolisation device comprises a flow restrictor having a contracted delivery configuration and an expanded deployed configuration. The flow restrictor comprises a disc shaped membrane. At least some of the plurality of flexible bristles are configured to urge the flow restrictor into the expanded deployed configuration and/or the contracted delivery configuration. At least a portion of the flow restrictor is located between bristles on both sides of the flow restrictor. The present invention provides an embolisation device that is easy to manufacture and which is more reliable upon deployment.
Patent NZ-743173-A (NZ)
Title: Sterilization reactor and method
Inventor: AROFIKIN NIKOLAY
IPC: A61L2/04
Filed: 2014-03-13
Abstract: A method and device to treat liquid to reduce the amount of microorganisms in the liquid to a preselected level and/or to mitigate the growth of microorganisms are disclosed. The reactor and method described herein may be used to treat a variety of liquids and may be particularly well suited for the treatment of food substances, such as dairy, non-frozen concentrate juices, and the like. The process for reducing the number of pathogens in a liquid utilises a reactor having at least (i) two spaced-apart walls, where each spaced-apart wall has an interior surface, (ii) an interior cavity between the interior surfaces of the at least two spaced-apart walls, (iii) an entrance to the interior cavity, and (iv) a nozzle centred at the entrance to the interior cavity. The method has the steps of: (a) heating the liquid before the liquid enters the nozzle; (b) spraying the liquid by the nozzle into the interior cavity; (c) subjecting the liquid to a pressure drop as it is being sprayed; and (d) increasing the temperature of the liquid when the liquid is in the interior cavity.
Patent NZ-744434-A (NZ)
Title: Methods and compositions for preventing norleucine misincorporation into proteins
Inventor: LAIRD MICHAEL
IPC: C12P21/02
Filed: 2013-09-19
Abstract: The present invention relates to methods and compositions for preventing incorporation of norleucine into proteins during recombinant protein production in bacteria via mutations in metA and metK alleles that cause overproduction of methionine. The present invention also provides microorganism host cells and nucleic acid molecules for use with the methods and compositions provided herein.
Patent NZ-745271-A (NZ)
Title: Blood brain barrier shuttle
Inventor: BOHRMANN BERND
IPC: C07K16/46
Filed: 2013-08-26
Abstract: The present invention relates to blood brain barrier shuttles that bind receptors on the blood brain barrier (R/BBB) and methods of using the same.