baber/WOPTO huggingface dataset:
Patent DE-69230612-D1 (DE)
Inventor: VANDENBARK ALLEN
IPC: A61K39/395
Filed: 1992-06-01
Granted: 2000-03-02
Abstract: Peptides and pharmaceutical compositions comprising immunogenic peptides of a marker T cell receptor (TCR) characteristic of an immune-related disease, capable of preventing, suppressing, or treating the disease, are disclosed. In a preferred embodiment, the amino acid sequence of the peptide corresponds to at least part of a complementarity determining region (CDR) or a hypervariable region of the TCR. Antibodies and/or T cells immunologically reactive to the TCR peptide capable of preventing, suppressing, or treating an immune-related disease by passive transfer are also disclosed.
Patent DE-69231071-D1 (DE)
Inventor: YOSHIZAWA HIROSHI
IPC: F16H59/66
Filed: 1992-08-27
Granted: 2000-06-21
Abstract: A control system of a vehicle automatic transmission. An engine load and a vehicle speed are detected and based on them, a vehicle acceleration to be obtained from the detected engine load and vehicle speed is determined in accordance with the preestablished characteristics. An actual vehicle acceleration is at the same time calculated in response to the detected vehicle speed. The difference therebetween is then calculated and the calculated value is added to a difference calculated earlier to obtain an average therebetween. Five gear shift scheduling maps, for example one for moderate hill climbing, one for level-road running, one for steep hill descent, are preestablished and in response to the average obtained, one of the maps is selected. A gear shifting is controlled based on the selected map. In a specific condition such as the engine load changes abruptly, braking is in progress and so on, the map selection is suspended and the control is carried out using the map selected earlier. <IMAGE>
Patent DE-69233119-D1 (DE)
Inventor: UNGER EVAN C
IPC: A61K9/127
Filed: 1992-03-31
Granted: 2003-08-07
Abstract: Drug delivery systems comprising gas filled liposomes prepared using vacuum drying gas instillation methods and having encapsulated therein a drug, and gas filled liposomes substantially devoid of liquid in the interior thereof and having encapsulated therein a drug, are described. Methods of and apparatus for preparing such liposomes and methods for employing such liposomes in drug delivery applications are also disclosed.
Patent DE-69303597-D1 (DE)
Inventor: MOHTASHAM MEHDI E J A ENG PLC
IPC: H01H27/00
Filed: 1993-05-28
Granted: 1996-08-14
Abstract: PCT No. PCT/GB93/01135 Sec. 371 Date Jun. 24, 1994 Sec. 102(e) Date Jun. 24, 1994 PCT Filed May 28, 1993 PCT Pub. No. WO93/24947 PCT Pub. Date Dec. 9, 1993A safety switch assembly for fitting to a safety enclosure. The switch includes a rotatable cam which operates electrical contacts. An actuator is insertable into the switch housing through either of two apertures to engage locking members. The locking members move in a rectilinear direction perpendicular to the cam axis away from the actuator and our of locking engagement with the cam. Ears on the actuator then engage in pockets in the cam and rotate the cam which causes movement of the electrical contacts to the ON position. Each locking member comprises a pair of locking components one of which is slidable on the other and both of which define elongate slots through which a cam shaft extends. The slots are inclined such that when the actuator pushes either one of the components away from a first aperture the other component is forced to move away from the other aperture.
Patent DE-69303634-D1 (DE)
Inventor: SERRUYS WIM
IPC: B21D5/02
Filed: 1993-02-03
Granted: 1996-08-22
Abstract: Method for controlling a programmable folding robot (3) for folding sheet-type items, in which the control is, inter alia, according to the principle of path control and by active compliance through force feedback. Programmable folding robot (3), of which the gripper (5) can be positioned according to various axes of movement by a horizontally mobile device (7), on which a swing arm (6) is rotatably fixed, while a mobile carriage (9) is provided on said swing arm (6), on which carriage a mechanism (10) which can make its outgoing part rotate about two perpendicular axes is provided, while the gripper (5) is provided on said outgoing part, and said gripper (5) is connected by means of a force sensor (11) to the outgoing part of mechanism (10), said force sensor (11) through its flexibility permitting a translation of the gripper (5) in two directions and a rotation about one axis relative to the outlet of the last movement shaft. Programmable device consisting of the combination of a folding machine (1) with reference post (2) and supply and discharge device, and a folding robot (3). <IMAGE>
Patent DE-69305783-D1 (DE)
Inventor: BRAMATTI VALERIO
IPC: C05G3/70
Filed: 1993-04-16
Granted: 1996-12-12
Abstract: The present invention relates to a water-soluble composition containing, as active ingredient, at least one plant-protection active material characterised in that it contains, in addition, at least an effective quantity of a compound of general formula I  RO-(A-O)n-CO-R'   I  in which:     R' represents a group <IMAGE> with M and M' representing, independently of each other a hydrogen atom, an alkali or alkaline-earth metal or an optionally substituted ammonium salt,   - R represents a linear or branched C1-C20 alkyl radical,   - A represents a linear or branched C2-C4 alkylene group, - n represents an integer or a decimal which may vary between 1 and 10, it being possible for A to be different in nature from one unit to another, n is greater than 1.   It also relates to the applications of the said composition as herbicide, fungicide or fertilizer.
Patent DE-69309753-D1 (DE)
Inventor: UEDAI YASUTSUGU
IPC: A61K31/665
Filed: 1993-02-09
Granted: 1997-05-22
Abstract: A taxol derivative of formula I <CHEM>  or a pharmaceutically acceptable salt thereof, in which   R<j> is   -COR<z> in which R<z> is t-butyloxy, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, or phenyl, optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups; R<y> is   C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, or a radical of the formula -W-R<x> in which W is a bond, C2-6 alkenediyl, or -(CH2)t-, in which t is one to six; and R<x> is naphthyl, furyl, thienyl or phenyl, and furthermore R<x> can be optionally substituted with one to three same or different C1-6 alkyl, C1-6 alkoxy, halogen or -CF3 groups; R<w> is   hydrogen, hydroxy, acetyloxy, -OC(=O)OY or -OZ; R<1> is   hydrogen, hydroxy, -OC(=O)OY or -OZ; R<2> is hydroxy, -OC(=O)OY, -OC(=O)R or -OZ, with the proviso at least one of R<1>, R<2> or R<w> is -OC(=O)OY or -OZ; R is   C1-6 alkyl; Z is   of the formula <CHEM>  or   <CHEM>  wherein   R<3> and R<4>   are independently hydrogen or C1-6 alkyl, or R<3> and R<4> taken together with the carbon atom to which they are attached form C3-6 cycloalkylidene; R<5> is   -OC(=O)R, -OP=O(OH)2 or -CH2OP=O(OH)2; R<6>, R<7>, R<8> and R<9>   are independently halogen, C1-6 alkyl, C1-6 alkoxy or hydrogen; or one of R<6>, R<7>, R<8> and R<9> is -OC(=O)R, -OP=O(OH)2 or hydroxy, and the others are independently halogen, C1-6 alkyl, C1-6 alkoxy or hydrogen; but when R<5> is -OC(=O)R, one of R<6>, R<7>, R<8> or R<9> must be -OP=O(OH)2; Q is   -(CH2)q-, optionally substituted with one to six same or different C1-6 alkyl or C3-6 cycloalkyl, or a carbon atom of said -(CH2)q- group can also be a part of C3-6 cycloalkylidene; q is   2 to 6; n is 0, and m is 1 or 0 when R<5> is -CH2OP=O(OH)2; n is 1 or 0, and m is 1 when R<5> is -OC(=O)R or -OP=O(OH)2; Y is   C1-6 alkyl (optionally substituted with -OP=O(OH)2 or one to six same or different halogen atoms), C3-6 cycloalkyl, C2-6 alkenyl, or a radical of the formula   <CHEM>  in which D is a bond or -(CH2)t-, optionally substituted with one to six same or different C1-6 alkyl; and R<a>, R<b> and R<c> are independently hydrogen, amino, C1-6alkylamino, di-C1-6alkylamino, halogen, C1-6 alkyl, or C1-6 alkoxy; and with the further proviso that R<2> cannot be -OP=O(OH)2; and Y cannot be -CH2CCl3.
Patent DE-69309815-D1 (DE)
Inventor: DEHENNAU CLAUDE
IPC: C08L23/02
Filed: 1993-08-19
Granted: 1997-05-22
Abstract: Polymeric compositions including at least one polyolefin, at least one thermoplastic starch and at least one ionic compound, the latter being present in a content such that the concentration of anions and of cations in the composition is from 0.002 to 5 mol/kg. The invention also relates to the masterbatch employed for the manufacture of these compositions and containing the thermoplastic starch and the ionic compound. The compositions are suitable in particular for the production of mono- or multilayer films usable especially in the paper industry.
Patent DE-69312493-D1 (DE)
Inventor: BENNETT WILLIAM
IPC: A61K38/46
Filed: 1993-05-28
Granted: 1997-09-04
Abstract: The invention concerns tissue plasminogen activator (t-PA) variants which are glycosylated at any of positions 103-105, and are devoid of functional carbohydrate structure at position 117 of wild-type human t-PA amino acid sequence. The variants have extended circulatory half-life and substantially retained fibrin binding, or improved in vivo fibrinolytic potency, as compared to wild-type human t-PA. <IMAGE>
Patent DE-69314022-D1 (DE)
Inventor: GRISAR J
IPC: A61K31/343
Filed: 1993-03-10
Granted: 1997-10-23
Abstract: Derivatives of 2,3-dihydro-5-benzofuranol, intermediates thereof, and processes useful for their preparation. These compounds are free radical scavengers and are useful in the treatment of conditions capable of being treated by free radical scavengers, such as stroke, nervous system trauma and reperfusion damage.
Patent DE-69316913-D1 (DE)
Inventor: GASTMANS ANDRE
IPC: C10C3/02
Filed: 1993-11-11
Granted: 1998-03-12
Abstract: The viscosity of bitumen, bitumen-like mixes based on polymer and bitumen and mixes of bitumen and additives is reduced by mixing said bitumen or mixes with at least one gas in a dynamic high shear mixer or in a static mixer.
Patent DE-69317700-D1 (DE)
Inventor: HARDS GRAHAM ALAN
IPC: H01M4/88
Filed: 1993-06-16
Granted: 1998-05-07
Abstract: A porous electrode suitable for use in a membrane electrode assembly for solid polymer fuel cells comprises a highly dispersed precious metal catalyst on particulate carbon impregnated with proton conducting polymer, and, a further component comprising hydrophobic polymer and a dispersion of particulate carbon, the loading of precious metal being 0.01-1.0mg/cm<2> of geometric electrode area. Said electrode demonstrates high effective platinum surface area and power density output when fabricated into a membrane electrode assembly.
Patent DE-69318296-D1 (DE)
Inventor: LAMANNA SAVERIO
IPC: B42D1/04
Filed: 1993-09-01
Granted: 1998-06-04
Abstract: Binding element, consisting of an actual file (2) which is composed of one or more parts, the back (3) of which contains an element (5) in a hard heat conducting material, and whereby the back (3) is provided at its inside with an amount of glue (4) which melts under the influence of heat, characterized in that the file (2), at least partially, is adjacent to the inside (6) of said element (5). <IMAGE>
Patent DE-69324680-D1 (DE)
Inventor: TIPPEY KEITH EDWARD
IPC: A61N1/05
Filed: 1993-05-21
Granted: 1999-06-02
Abstract: PCT No. PCT/GB93/01059 Sec. 371 Date Nov. 8, 1994 Sec. 102(e) Date Nov. 8, 1994 PCT Filed May 21, 1993 PCT Pub. No. WO93/24176 PCT Pub. Date Dec. 9, 1993Electrical stimulation for the treatment of neuro-muscular disorders, in particular incontinence. A portable electrical stimulation apparatus for treatment of incontinence, comprising one or more electrodes (302) for applying one or more electrical stimulation signals to a patient's body, a signal generator for generating the electrical stimulation signal(s), one or more conductive leads for connecting the signal generator to the electrode(s), to deliver the electrical stimulation signal to the electrode(s); and a power supply, characterized in that the apparatus includes an instruction storage or a programming device for imparting a set of instructions to the signal generator, the signal generator being responsive to the instruction storage or programming device so that the generated signal adopts signal waveform characteristics selected in accordance with said set of instructions.
Patent DE-69324999-D1 (DE)
Inventor: WINNIKE DON
IPC: F16K47/00
Filed: 1993-03-04
Granted: 1999-06-24
Abstract: A snubber which may be used with a diaphragm actuator or other movable member to prevent sudden movement of the movable member is provided. A typical diaphragm actuator has a diaphragm housing (50) with a movable diaphragm (56) therein dividing the diaphragm housing into two separate chambers (80,82). An actuator stem (66) is connected to the diaphragm to move with the diaphragm. The snubber (90) has a housing (92) with an open interior space communicating through a communication path with a first one (82) of the actuator chambers. A first piston (110) is reciprocably movable within the snubber housing, the first piston being operably connected to the actuator stem to move therewith. The first piston divides the snubber housing space into two chambers, one on each side of the first piston. A passage (102,100,108) is provided which leads from one of the snubber chambers to the other. A floating piston (116) positioned in the communication path between the first piston and the first actuator chamber. Thus, as the first piston reciprocates within the snubber space, the floating piston moves in an opposite direction to accommodate the changing volume within the snubber space occasioned by the movement of the first piston into and out of the snubber space. <IMAGE>
Patent DE-69331264-D1 (DE)
Inventor: RICHARDSON THOMSON
IPC: H04Q3/72
Filed: 1993-03-19
Granted: 2002-01-17
Abstract: Method and apparatus for providing customized telecommunication services through a peripheral node which includes a node interface for connection through incoming and outgoing telephone trunks to a carrier switch of a public switched network, an audio response unit for recording, playing, and analyzing audio signals, and a node controller for controlling operation of the node interface and the audio response unit.
Patent DE-69409779-D1 (DE)
Inventor: BRAUN EUGENE RALPH
IPC: F16D23/06
Filed: 1994-12-19
Granted: 1998-05-28
Abstract: A baulkring-type synchronizer mechanism (18) includes cone clutch friction surfaces (24,48 and 26,50) and sets jaw clutch teeth (58,28 and 60,30) for frictionally synchronizing and positive connecting gears (14,16) to a shaft (12). Blocker teeth on baulkrings (40,42) prevent asynchronous engagement of the jaw clutch teeth and transmit operator shift forces (Fo) from a shift sleeve (34) to the cone clutches. Angled self-energizing surfaces (72a,72b,74a,74b) are affixed to an outer circumference of a hub (32) and engage angled self-energizing surfaces (76a,76b,76c,76d) affixed to a shift sleeve (34) to provide an additive force (Fa) that is transmitted via the blocker teeth to the cone clutches. The jaw clutch teeth include axially movable first and second sets of teeth (58,60) defined by the shift sleeve (34) and axially fixed sets of teeth (28,30) secured to the gears. When the sleeve is in a neutral position, the first and second sets of the teeth (58,60) are loosely disposed respectively in portions of grooves in hub (32). When one of the first and second sets of teeth (58,60) are engaged with one of the fixed sets of teeth, the other of the first and second sets is closely received in a portion of its associated groove. <IMAGE>
Patent DE-69418345-D1 (DE)
Inventor: PFAENDNER RUDOLF
IPC: C08L27/08
Filed: 1994-12-09
Granted: 1999-06-10
Abstract: PCT No. PCT/EP94/04105 Sec. 371 Date Jun. 20, 1996 Sec. 102(e) Date Jun. 20, 1996 PCT Filed Dec. 9, 1994 PCT Pub. No. WO95/17465 PCT Pub. Date Jun. 29, 1995Plastic mixtures, in particular recycled plastic mixtures, comprising predominantly polyolefins and 0.05-20% by weight of PVDC can be stabilized against thermo-oxidative degradation by addition of a combination of an organic phosphite or phosphonite and a metal salt of a fatty acid.
Patent DE-69421559-D1 (DE)
Inventor: SHAFFER MYRON W
IPC: C08G18/32
Filed: 1994-03-02
Granted: 1999-12-16
Abstract: The present invention relates to process for preparing a coated substrate having improved resistance to yellowing which comprises coating a substrate with a one-component coating composition containing   a) a blocked polyisocyanate which is the reaction product of a polyisocyanate with an oxime or lactam blocking agent for isocyanate groups and   b) a compound containing at least two isocyanate-reactive groups, provided that component a) and/or component b) contains the group, -CO-(R)N-N(R)-CO-, wherein R represents hydrogen or an optionally substituted hydrocarbon radical, in an amount of 0.01 to 5% by weight, based on the solids content of components a) and b), by applying the one-component coating composition wet-on-wet to a coating composition containing acid groups and/or melamine resins which has previously been applied to the substrate or by adding a melamine resin to the one-component coating composition prior to applying it to the substrate, which may optionally have been precoated. The present invention also relates to the coated substrate having improved resistance to yellowing prepared by this process.
Patent DE-69422343-D1 (DE)
Inventor: AKAGIRI KENZO
IPC: H03M7/30
Filed: 1994-02-18
Granted: 2000-02-03
Abstract: An apparatus, method, and system in which a compressed digital signal is derived from a digital input signal by compressing the digital input signal in a selected one of plural compression modes. The digital output signal has a different bit rate in each compression mode, but the digital input signal is received at the same bit rate in all the compression modes. In the method, spectral coefficients are derived from the digital input signal, and are grouped by frequency and by time into bands. Each band has a frequency width, and the frequency width of at least one of the bands is set according to the selected compression mode. The spectral coefficients in each band are quantized to provide quantized spectral coefficients. Finally, the quantized spectral coefficients in each band are included in the compressed digital signal, together with sub information for each band.
Patent DE-69423011-D1 (DE)
Inventor: JOHANSSON KERSTIN
IPC: A61F13/72
Filed: 1994-10-06
Granted: 2000-03-16
Abstract: PCT No. PCT/SE94/00933 Sec. 371 Date Mar. 20, 1996 Sec. 102(e) Date Mar. 20, 1996 PCT Filed Oct. 6, 1994 PCT Pub. No. WO95/09592 PCT Pub. Date Apr. 13, 1995The present invention relates to a sanitary napkin or like absorbent article, such as a sanitary pantie or incontinence guard, comprising an absorbent body (8) which is enclosed between a fluid-permeable (15) and a fluid-impermeable casing sheet (17). According to the invention, the absorbent body (8) comprises a primary absorbent body (9) having the capacity to absorb all fluid discharged from a user over an intended article use period, and a secondary absorbent body (10) whose area is at least 50% larger than the area of the primary absorbent body.
Patent DE-69423900-D1 (DE)
Inventor: HERSH STUART
IPC: B05B7/04
Filed: 1994-09-09
Granted: 2000-05-11
Abstract: A fluid atomizer and spraying means which is made up of: a mixing chamber into which the fluid to be atomized and the atomizing gas are introduced and in which the fluid is admixed with and dispersed in the gas; a generally conical nozzle means extending from the mixing chamber through which the mixed fluid and gas are forced; and a chamber into which the atomized mixed fluid and gas is sprayed. The conical nozzle means is suitably a relatively narrow frustro-conical passageway which contains support-spacer means which is generally parallel to the direction of flow through the passageway. At least one such support-spacer means is provided which extends from the end of the passageway proximate to the mixing chamber to the end of the passageway proximate to the chamber into which the mixture is sprayed. The preferred use of this apparatus is in atomizing fuel oil with steam and spraying such atomized mixture into a combustion chamber where it is contacted with combustion air. The amount of effluent NOX is reduced and limited by the use of this configuration by creating alternating fuel-rich and air-rich spatial distribution, and allowing the amount of stoichiometric excess air to be severely limited, while causing the substantially complete combustion of the fuel oil.
Patent DE-69424295-D1 (DE)
Inventor: HOSONO HIROSHI
IPC: A61P43/00
Filed: 1994-08-01
Granted: 2000-06-08
Abstract: Provision of a succinamic acid compound of the formula (1) <CHEM> wherein R<1> is an alkyl or a lower alkenyl and R<2> is an optionally esterified carboxyl, a pharmaceutically acceptable salt thereof, an agent for the prophylaxis and/or treatment of the complications of diabetes, comprising, as an active ingredient, the succinamic acid compound or a pharmaceutically acceptable salt thereof, an aldose reductase inhibitor comprising, as an active ingredient, the succinamic acid compound or a pharmaceutically acceptable salt thereof, and a method for producing the succinamic acid compound or a pharmaceutically acceptable salt thereof. The novel succinamic acid compounds of the formula (1) of the present invention and pharmaceutically acceptable salts thereof have a strong aldose reductase inhibitory activity in mammals such as human, and show superior safety. Hence, they are useful as pharmaceutical agents for the treatment of the complications of diabetes such as faulty union of corneal injury, cataract, neurosis, retinopathy and nephropathy, in particular, cataract and neurosis. According to the production method of the present invention, efficient production of such useful compounds of the present invention can be provided.
Patent DE-69430584-D1 (DE)
Inventor: LICHTI ROBERT D
IPC: B65G1/133
Filed: 1994-10-31
Granted: 2002-06-13
Abstract: A storage system including a container storage area in the form of a multi-rack, multi-tier storage carousel, a vertical conveyor for transporting conveyors vertically and input and output shuttle units for conveying containers between the vertical conveyor and the storage carousel. The vertical conveyor includes a loading zone which is below the operating levels of the shuttle units. The storage carousel and the shuttle units are driven by a common mechanically synchronized drive. The vertical conveyor is driven intermittently and independently of the drive for the rest of the system.
Patent DE-69504634-D1 (DE)
Inventor: KIM SUN HYUK
IPC: C07K7/08
Filed: 1995-03-13
Granted: 1998-10-15
Abstract: The invention features linear therapeutic peptides of the following formula: <CHEM> in which A<1> is a D- alpha -aromatic amino acid or a D- alpha -tethered amino acid; A<2> is Gln, His, 1-methyl-His, or 3-methyl-His; A<3> is the D- or L-isomer selected from Nal, Trp, Phe, and p-X-Phe, where X is F, Cl, Br, NO2, OH or CH3; A<4> is Ala, Val, Leu, Ile, Nle, or  alpha -aminobutyric acid; A<5> is Val, Ala, Leu, Ile, Nle, Thr, or  alpha -aminobutyric acid; A<6> is  beta -Ala; A<7> is His, 1-methyl-His, 3-methyl-His, Lys, or  epsilon -alkyl-Lys; A<8> is Leu, Ile, Val, Nle,  alpha -aminobutyric acid, Trp, Pro, Nal, Chx-Ala, Phe, or p-X-Phe, where X is F, Cl, Br, NO2, OH or CH3; A<9> is Met, Met-oxide, Leu, Ile, Nle,  alpha -aminobutyric acid, or Cys; each R1 and R2, independently, is H, C1-12 alkyl, C7-10 phenylalkyl, or COE1, where E1 is C1-20 alkyl, C3-20 alkenyl, C3-20 alkynyl, phenyl, 3,4-dihydroxyphenylalkyl, naphthyl, or C7-10 phenylalkyl; provided that when either R1 or R2 is COE1, the other must be H; and R3 is OH, NH2, C1-12 alkoxy, C7-10 phenylalkoxy, C11-20 naphthylalkoxy, C1-12 alkylamino, C7-10 phenylalkylamino, C11-20 naphthylalkylamino; or a pharmaceutically acceptable salt of such peptides. <IMAGE>