baber/WOPTO huggingface dataset:
Patent UY-38236-A (UY)
Title: COMBINACIONES FARMACÉUTICAS QUE CONTIENEN EL ANTICUERPO ANTI-CD38, ASOCIADO CON LOS ANTICUERPOS BIOESPECÍFICOS BCMAxCD3 O GPRC5DxCD3 O CD19xCD3
Inventor: GAUDET FRANCOIS
IPC: C07K16/46
Filed: 2019-05-16
Abstract: Se describen combinaciones farmacéuticas que contienen el anticuerpo anti CD-38 asociado con el anticuerpo bioespecífico BCMAxCD3 o con el anticuerpo bioespecífico GPRC5DxCD3 o con el anticuerpo biespecífico CD19xCD3 o con el anticuerpo bioespecífico CD19xCD3, y métodos para tratar cánceres y potenciar la eficacia de terapéuticas de redireccionamiento de células T.
Patent UY-39265-A (UY)
Title: Compuestos como activadores de cav1.2 y composiciones farmacéuticas que los contienen
Inventor: NEEF JAMES
IPC: C07D498/04
Filed: 2021-06-11
Abstract: La presente divulgación proporciona un compuesto de acuerdo con la fórmula (I) o una sal farmacéuticamente aceptable de este como activadores de CaV1.22 para el tratamiento de esquizofrenia, trastorno bipolar, trastorno depresivo mayor, trastorno debido al uso de sustancias, TDAH, síndrome de Phelan-McDermid, trastornos del espectro autista, esclerosis múltiple, demencia frontotemporal, enfermedad de Alzheimer, síndrome de Brugada, síndrome de QT corto, o síndrome de repolarización precoz.
Patent YU-80500-A (YU)
Inventor: OON CHONG JIN
IPC: G01N33/53
Filed: 1998-06-19
Abstract: Pronalazak obezbedjuje soj izolovanog virusa hepatitisa B označenog kao humani Hepatitis B virus sa površinskim antigenom-'S'- soj 145. Singapur (Glicin do Arginina) koji sačinjava virusni genom koji je deponovan pod pristupnim br. P97121504, P97121505, i P9712156 sa evropskom kolekcijom ćelijske kulture 15.decembra 1997. Ovaj pronalazak takodje obezbedjuje izolovanu nukleinsku kiselinu koja kodira polipeptid koji je mutant glavnog površinskog antigena soja virusa Hepatitisa B, takav polipeptid ima aminokiselinsku sekvencu koja se razlikuje od aminokiselinske sekvence glavnog površinskog antigena divljeg tipa virusa hepatitisa B u kojem je aminokiselina na mestu broj 145 takvog polipeptida češće arginin nego glicin, i prečišćeni peptid. Pronalazak takodje obezbedjuje izolovanu nukleinsku kiselinu koja kodira peptid, u kojem je peptid kodiran molekulom nukleinske kiseline koji obuhvata nukleotide 527 do 595 za SEQ. ID. br. 1, i prečišćeni peptid.
Patent YU-85389-A (YU)
Title: Device for magnetotherapy
Inventor: TSYB A F
IPC: A61N2/04
Filed: 1989-04-24
Abstract: A magnetotherapy device comprises a controlled current pulse generator (1), an energy accumulator (2) and an accumulator discharge circuit (3) including a controlled switching element (5) and an inductor (4) capable of creating a magnetic pulse curative field, as well as a unit (7) for control of the magnetic field pulse duration of the inductor and a magnetic field pulse amplitude regulator (10). The accumulator discharge unit (3) contains a unit (6) for regulating the steepness of the wave front of the inductor magnetic field pulses. The device is essentially intended for stopping sharp pain syndroms, phantom pains, bronchial asthma attacks while treating mastitis in cattle.
Patent YU-95290-A (YU)
Title: Anti-inflamatorni derivati aminofenola
Inventor: BANTICK J R
Filed: 1990-05-16
Abstract: ANTI-INFLAMATORNI DERIVATI AMINOFENOLA. Opisana su jedinjenja formule I: u kojoj: R1 predstavlja C(O)YZ ili SO2R10, Y predstavlja prostu vezu, O, NR11 ili CO, Z predstavlja vodonik, alkil ili alkil supstituisan sa jednim ili više supstituenata izabranih iz grupe koja sadrži hidroksi, alkoksi, aciloksi, karboksi, alkoksikarbonil, CONR12R13, arilalkoksi, Ar1, heterocikl, halo, cijano ili NR14R15, R2, R3, R5 i R6, koji mogu biti različiti, predstavljaju vodonik, alkil, alkoksi ili halogen, R4 i R11, koji mogu biti isti ili različiti, predstavljaju vodonik ili alkil, R10 predstavlja alkil, X predstavlja heterocikl koji je opciono supstituisan sa jednim ili više supstituenata izabranih iz grupe koja sadrži alkil, cikloalkil, alkoksi, alkoksikarbonil, karboksi, hidroksialkil, halo, CONR16R17, NR18R19 ili Ar2, Ar1 i Ar2, koji mogu biti isti ili različiti, predstavljaju aril ili aril supstituisan sa jednim ili više sustituenata izabranih od halogena, nitro, alkoksi, karboksi, alkil ili trihaloalkil, R12, R13, R14, R15, R16, R17, R18 i R19, koji mogu biti isti ili različiti predstavljaju vodonik, alkil ili benziloksikarbonil, ili njihovi farmaceutski prihvatljivi N-oksidi, N-alkil derivati, soli, estarski ili amidni derivati, za korišćenje kao farmaceutskog sredstva, n.pr., kao anti-inflamatornog sredstva.
Patent YU-2903-A (YU)
Title: Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same
Inventor: DIAZ JACQUES
IPC: C08B37/00
Filed: 2001-07-18
Abstract: The invention concerns heparin-derived polysaccharide mixtures, their preparation method and pharmaceutical compositions containing them
Patent AT-A236488-A (AT)
Inventor: WEIHS HANS ING
IPC: G06K17/00
Filed: 1988-09-23
Abstract: In a scanning device for a chip card (2) which has a fixedly arranged contact set (3), to which a chip card placed in an adjustable receiving device can be approached with the contacts provided on it, the receiving device is constructed as a level-adjustable drawer (7) into which the chip card, in its position when withdrawn from the device, can be inserted into a receiving space within the draw, in which it lies on a level at a distance from the level of the contact set, and connecting link guides (29, 30) are provided for adjusting the drawer on both sides which co-operate with said draw and which, when inserting it into the device in the region of the contact set, adjust the draw in steps to its level. 
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Patent BE-894224-A (BE)
Title: High thermal capacity solar heating installation - has low temperature melting solid as primary heat collector which is recrystallised in cold chamber
IPC: F24D11/02
Filed: 1982-08-27
Abstract: The installation has the insulator (1) containing the solid (5) to be melted, with cistern (2) connected to insulator to collect the melted product (5'). A cold chamber (3) is connected to the cistern via the valve (6) and when the valve is open, the product recrystallises in chamber giving up its heat to the heat carrying fluid in the heat exchange circuit (14) which passes through it. The pump (4) has a primary circuit (15) supplied by the heated fluid and a secondary circuit (16) connected to the usage circuit (U), while a return circuit (13) returns the recrystallised product to the insulator.
Patent BE-900761-A (BE)
Title: Masses ou corps refractaires en particulier, pour le garnissage de fours ou de recipients pour metaux en fusion.
IPC: C04B35/565
Filed: 1984-10-05
Abstract: Les masses ou les corps réfractaires, en particulier, pour le garnissage de fours ou de récipients pour métaux en fusion sont à base de silicates d'aluminium, d'oxyde d'aluminium, de dioxyde de silicium, de silicate de zirconium et de carbure de silicium, d'additifs habituels et d'agents liants comme mélange de départ; Ces masses ou corps, lors de la fabrication desquels on ajoute 0,5 à 40% en poids de sulfate de baryum pour la formation de celsian (BaO.Al2O3O3.2 SiO2) et, en outre,3 à 25 parties en poids de fluorure de calcium, calculé sur 100 parties en poids du sulfate de bayum ajouteé
Patent CA-1160345-A (CA)
Inventor: MCDONALD GEORGE B
IPC: G01L23/00
Filed: 1972-08-31
Granted: 1984-01-10
Abstract: ABSTRACT OF THE DISCLOSURE         It is known to obtain a correction factor by determining theoretical gross thrust by measuring engine pressures and by measuring actual gross thrust and using a comparison between theoretical and measured gross thrust to develop a correction factor.  However the correction factor is variable in accordance with certain engine pressures and requires the use of elaborate altitude test cell facilities to define it for a practical working range.  This invention measures engine pressures in a static sea level facility, derives a correction factor to be applied to one of the measured pressures for use in a determination of gross thrust useful under all operating conditions.
Patent CA-1043014-A (CA)
Inventor: BRUNONE PETER P
IPC: B67D7/22
Filed: 1974-07-23
Granted: 1978-11-21
Abstract: ABSTRACT         A twelve pump fuel delivery control and registra-tion system for controlling self-service operation of each fuel pump and for selectively registering the volume and cost amounts of each fuel delivery for charging the self-service customers.  The system is also selectively operable for registering the total cost and volume amounts of three available grades of fuel delivered by the twelve pumps.
Patent CA-1050223-A (CA)
Inventor: WIMMER ROBERT
IPC: B29C70/34
Filed: 1975-01-03
Granted: 1979-03-13
Abstract: Abstract of the Disclosure In a process of manufacturing composite bodies from thermoplastic material and glass fibre-reinforce-ed, hardenable plastics material, thermoplastic sheeting consisting particularly of polymethacrylate (acrylic glass) is used to make a preform which determines the basic shape of the end product and preferably forms its exposed side. The sheeting is coated at least on one side with the glass fibre-reinforced, hardenable plastic material, particularly unsaturated polyester resin (thermosettable resin), with additional use of a bond-improving agent. This coating is compacted and then permitted to harden. The surface of the preform on the side to be coated is contacted with a solvent for the thermoplastic material, which solvent consists, e.g., of an acryl monomer, styrene, acetone, methylene chloride, etc., before or during the application of the coating of the hardenable plastics material and for a time which is suffi-cient for a slight dissolution of the thermoplastic material in the area to be coated. As a result, the glass fibres can slightly enter the thermoplastic material during the applicat-tion and/or compacting of the coating material and the end product obtained after the hardening of the hardenable plas-tics material has a transitional zone in which the thermo-plastic material and the glass fibre-reinforced, hardenable plastics material are contained and inseparable joined.
Patent CA-1046412-A (CA)
Inventor: FOGEL ARNOLD W
IPC: A61K8/41
Filed: 1975-01-13
Granted: 1979-01-16
Abstract: UNITED STATES PATENT APPLICATION                OF           ARNOLD W. FOGEl AND                  ANTHONY F. MERCURIO         FOR            SHAMPOO COMPOSITION WITH IMPROVED   HAIR CONDITIONING PROPERTIES              ABSTRACT OF THE DISCLOSURE         A shampoo, creme rinse composition is provided com-prising an anionic or amphoteric detergent, or combinations thereof and a substituted quaternary ammonium compound repre-sented by the formula:                             where R1 and R2 are lower alkyl of 1 to 4 carbon atoms;     R3 is a benzyl radical which may be further substituted by a C1 or C2 alkyl radical;     R4 is a long chain alkyl radical of 16 to 22 carbon atoms; and X is an organic anion selected from the group consisting of saccharinate, cyclamate and phthalimidate radicals.
Patent CA-1043419-A (CA)
Inventor: TAMMINEN PENTTI J
IPC: H01M6/42
Filed: 1975-01-16
Granted: 1978-11-28
Abstract: Alkaline Flat Cell Battery Abstract of the Disclosure A hermetically sealed flat cell with an alkaline electrolyte and a battery made out of a number of such cells Both the positive and the negative electrode layer of each cell of the battery is provided with a supporting plate preferably covering the whole outside of respective layer.          Said plate incorporates a current collector, the outside of each current collector being provided at the contact area with a relatively th ick,  plastic and sticky layer of che-mically inert, water repellent adhesive.  Each cell is cow red with a plastics sheet that is preferably laminated and comprises two layers, the inside layer of which is chemically resistant ant heat sealable, the outside layer being mechanically tough and resistant to oxygen trans-mission.  Enclosing of each cell has been carried out by means of heat sealing in a vacuum.  When assembling a battery there is provided at said adhesive layer on both sides of each cell a contact member consisting of a prefe-rably spiral-shaped pressure spring with sharp edges facing opposite directions, adapted to pierce said plastic cover, the pitch of said spring allowing under pressure ample latitude of elastic movement so as to secure a firm elec-trical contact of said edges to the current collectors within each cell.
Patent CA-1067885-A (CA)
Title: Metal grinding and cutting aids and methods of manufacturing and using the same
Inventor: WIRTH JOHN C J
IPC: B24B1/00
Filed: 1975-02-19
Granted: 1979-12-11
Abstract: ABSTRACT OF THE DISCLOSURE       A grinding and cutting process and articles em-ploying an effective amount of a grinding aid, typical of which is sodium nitrite which, when applied to the abradent or cutting edge of a tool, accelerates the modification of a metal workpiece and prolongs the useful life of the tool. The grinding aids of this invention are compounds free of sulfur and/or halogen and having a melting point in the range of 70°F. to 1000°F., a decomposition temperature at least 100°F. above the melting temperature and a latent heat of melting greater than 10 cal/gm.
Patent CA-1038761-A (CA)
Inventor: ONO HIROOMI
IPC: A61K31/05
Filed: 1975-03-14
Granted: 1978-09-19
Abstract: COMPOSITION FOR CONTROLLING SEXUAL BEHAVIOR OF MAMMALS     ABSTRACT OF THE DISCLOSURE         An injectable composition for controlling the sexual behavior of mammals containing as effective ingredients hexestrol difatty acid ester and testosterone fatty acid ester in a weight ratio of 0.5 to 10 : 10 to 0.5.
Patent CA-1059160-A (CA)
Inventor: FROST RODNEY I
IPC: C04B35/195
Filed: 1975-04-15
Granted: 1979-07-24
Abstract: METHOD OF PREPARING CRACK-FREE     MONOLITHIC POLYCRYSTALLINE CORDIERITE SUBSTRATES                 Abstract of the Disclosure Cracking of large monolithic cordierite segments and in particular monolithic honeycombed substrates having a matrix of thin walls forming a multiplicity of open ended cells extending from one end of the substrate to the other end is reduced or eliminated by limiting the amount of raw clay used in formulating the clay-talc-alumina raw material batch.  The raw clay may be eliminated entirely but is preferably at least 10% of the whole batch and not more than 31% of the whole batch with the balance of the clay constituent to the raw material batch being calcined clay.  The raw material batch is preferably formulated to yield at least 90% cordierite phase upon reaction during sintering.
Patent CA-1066846-A (CA)
Title: Preparation of polyphenylene oxide using a manganese (ii) ortho-hydroxyareneoxime chelate reaction promoter
Inventor: OLANDER WALTER K
IPC: C08G65/00
Filed: 1975-06-26
Granted: 1979-11-20
Abstract: ABSTRACT OF THE DISCLOSURE           A process for the preparation of polyphenylene oxide employing a manganese (II) ortho-hydroxyareneoxime chelate catalyst is described.  The process can be effectively carried out both in the absence as well as in the presence of amines. The process is economical and useful in the production of polyphenylene oxide resins.
Patent CA-1060453-A (CA)
Inventor: WILLIAM FRANK J III
IPC: C08G73/10
Filed: 1975-07-14
Granted: 1979-08-14
Abstract: POLYTHIOETHERIMIDES                Abstract of the Disclosure Polythioetherimides are provided by either effect-ing reaction between aromatic bis(thioetheranhydride) and organic diamine or by nitro- or halo-displacement from appropriately substituted bis(phthalimide) with anhydrous alkali metal sulfide.  The polythioetherimides are heat and flame resistant and can be reinforced with various fillers to produce high performance composites.  The polythioether-imides also can be used as wire coating enamels when used in phenolic solvent.
Patent CA-1054735-A (CA)
Inventor: WINKLER C
IPC: B66B1/18
Filed: 1975-08-06
Granted: 1979-05-15
Abstract: ABSTRACT OF THE DISCLOSURE An elevator system with an asynchronous-synchronous interface between the system processor and each car con-troller.  Each interface includes a serially accessed memory which intermittently receives command words from the system processor.  The serially accessed memory repetitively reads out the commands to the car controller, and updates the com-mands in response to a new data word without interrupting the flow of data to the car controller.  Each interface util-izes internal logic and timing for controlling its serially accessed memory, thus relaxing the memory capacity and pro-cessing speed requirements of the system processor.
Patent CA-1050123-A (CA)
Inventor: KUMBATOVIC ROBERT A
IPC: H03K17/042
Filed: 1975-08-25
Granted: 1979-03-06
Abstract: Abstract The circuit includes a first switching device having an input and an output and which in response to the presence of a signal at its input produces an out-of-phase signal at its output.  A capacitor is connected, at one end, to the output of the first device.  A second, normally open, switching device is connected between the other end of the capacitor and the input of the first device.  When the first device is turned on, the signal at its output is coupled from one end to the other end of the capacitor and the capac-itor functions to level shift and store the signal at its other end.  The stored signal exceeds the range of the operating potential applied to the circuit and may be used to turn off the first switching device when the, normally open, second switching device is closed.
Patent CA-1058441-A (CA)
Inventor: STANGROOM MAX
IPC: A21D13/00
Filed: 1975-11-10
Granted: 1979-07-17
Abstract: ABSTRACT OF THE DISCLOSURE         A pizza capable of being baked using micro-wave energy, i.e., in a micro-wave oven, while remaining crisp is prepared from a dough comprising:  (i)  from about 75 percent to about 82 percent by weight flour, preferably a medium to weak strength bleached, low gluten flour: (ii)  up to about 5 percent by weight shortening, animal or vegetable shortening; and (iii) from about 18 percent to about 25 percent by weight moisture.  In preparing the pizza, a dough of the above composition is shaped into the shape of a pizza crust and thereafter dried in a con-vection or micro-wave oven to a moisture content of from about 3 percent to about 8 percent by weight.  After the addition of pizza toppings, i.e., sauce and cheese and any additional ingredients, to the dried crust, the dried crust and pizza toppings can be baked in a micro-wave oven using micro-wave energy, the crust remaining crisp throughout the baking.  The pizza can be baked in the micro-wave oven either packaged or unpackaged and can be baked either frozen or unfrozen.
Patent CA-1073659-A (CA)
Inventor: LASHWAY ROBERT W
IPC: B28B21/42
Filed: 1976-01-16
Granted: 1980-03-18
Abstract: ABSTRACT OF THE DISCLOSURE      A boron nitride crucible, suitable for the vaporiza-tion of aluminum, having a multi-walled structure comprising an outer wall and a thinner inner wall weakly bonded to the thicker outer wall.  Because of this structure, the crucible is considerably more flexible than conventional single-walled crucibles and exhibits substantially improved thermal cycling characteristics and longer life.  The cru-cible is produced by depositing pyrolytic boron nitride upon a mandrel having the shape of the desired crucible at a temperature of from about 1850°C. to about 2100°C. until a first layer of boron nitride of suitable thickness has been produced, interrupting the deposition of boron nitride upon the mandrel and lowering the temperature to below 1750°C., and then depositing additional boron nitride upon the mandrel at a temperature of from about 1850°C. to about 2100°C. to produce a second outer layer of boron nitride having a thickness greater than that of the inner layer.
Patent CA-1083921-A (CA)
Inventor: MEINDERSMA ELIZE
IPC: F16K24/06
Filed: 1976-02-02
Granted: 1980-08-19
Abstract: Abstract of the Disclosure A vacuum breaker valve of the type used to prevent collapse of a fuel tank or the like while it is being pumped out.          The valve includes a hollow body which is secured in an aperture in the vessel, a valve stem mounted for reciprocal motion in the body, and a valve head on the stem which co-operates with a valve seat on the body.  The valve head is spring biased toward a normally closed position.  An air inlet port is provided in communication with an air passage around the stem and an outlet port communicating with the valve seat  thus allowing air to enter the vessel when the valve head is moved from the seat by excessive pressure.
Patent CA-1055666-A (CA)
Inventor: HOVILA HARRY
IPC: B29C35/08
Filed: 1976-03-26
Granted: 1979-06-05
Abstract: VULCANIZING APPARATUS                 Abstract The vulcanizing apparatus of the present invention can be used for vulcanizing spliced sections of rubber belting, sheeting or the like.  The apparatus includes an upper platen assembly and a lower platen assembly.  The upper platen assembly includes an upper frame member and a sheet-like platen member having a relatively rigid platen surface.  The platen member is affixed to an upper frame member.  A heat exchanger, a heating pad and a layer of insulation are sandwiched between the sheet-like platen member and the upper frame member.  The lower platen assembly includes a lower frame member and a sheet-like platen member having a relatively rigid platen surface, below which are interposed in sandwiched relationship a heat exchanger, a heating pad, and a layer of insulation.  The layer of insulation rests upon a flexible diaphragm that has a flexible surface substantially co-extensive with the lower platen surface.  The peripheral portions of the diaphragm surrounding the platen surface co-extensive portion are affixed to a lower frame member in sealed relationship, forming a fluid pressure chamber between the lower surface of the diaphragm and the lower frame member.  An inlet to the pressure chamber is provided fro admitting a fluid under pressure into the chamber and for exhausting the fluid.  Connecting members, in the form of bolts pivotally mounted to the lower frame member and removably secured in appropriately positioned slots in the upper frame member, position and hold the upper platen surface in mutually opposing spaced relationship to the lower platen surface when a belt or other material to be vulcanized is interposed between the two platen surfaces.  In use, a pressur-ized fluid is injected into the pressure chamber in the lower platen assembly causing the flexible diaphragm and the portion of the lower platen assembly resting on it to move upwardly, compres-sing the belt or other work piece to be vulcanized between the upper and lower platen surfaces.  Thereafter, the heating pads are energized to heat the workpiece to vulcanizing temperature. After the workpiece is vulcanized, the heating pad is de-energized and a cooling fluid is injected into the heat exchangers to cool the work piece sufficiently for handling.  Thereafter, the pressure is released from the pressure chamber, the bolts holding the upper and lower platen assemblies together are uncoupled, the upper platen assembly is lifted off the belt, and the belt is removed and placed in use.