Patent EA-003208-B1 (EA)
Title: Nutritional spray microemulsion useful as biodegradation accelerator
Inventor: TELLIER JACQUES
IPC: C09K23/14
Filed: 2000-07-05
Abstract: 1. A microemulsion, as a biodegradation accelerator, which is stable in the temperature range from -10 degree C to +50 degree C comprising nitrogen-containing compounds, such as for example, amino acids, proteins or urea, surfactant phosphoric compounds of types of alkyl or alkenyl ester of phosphoric acid and compounds, selected from group consisting of vegetable or animal oils or fatty acids and diluent - wherein it contains from 10-35% by weight of surfactant mono- or di- alkyl or mono- or di- alkenyl ester of phosphoric acid, the alkyl and alkenyl groups containing less than 12 carbon atoms per group, preferably from 4 to 10, and the ester containing from 1 to 10 alkoxy groups, preferably ethoxygroups or propxygroups, and from 3 to 20% by weight of at least one cosurfactant, and has a viscosity at 5 degree C. less than or equal to 200 mPaxsec. 2. The microemulsion according to claim 1, wherein cosurfactants have an oral toxicity in rats such that the lethal dose for 50% of the rats is higher than 2 g/kg. 3. The microemulsion according to claims 1-2, wherein cosurfactant has a melting point lower than 0 degree C, and preferably lower -20 degree C, and/or a solubility in water higher than 2 g in 100 g of water at temperature of 20 degree C, and preferably higher of 10 g in 100 g of water. 4. The microemulsion according to claims 1-3, wherein cosurfactants, alone or in a mixture, are selected from the group consisting of mono and polyhydroxylated alcohols containing less than 10 carbon atoms and their ether derivatives, mono- and polycarboxylic compounds, in particular, acids, or esters with C1 to C7 carbonic chains, possibly mono or polyhydroxylated, or straight and cyclic ketones containing not more than 5 carbon atoms, and lactones. 5. The microemulsion according to claims 1-4, wherein the monoalcohols are (C2 - C8) alkanols. 6. The microemulsion according to claims 1-5, wherein polyalcohols are diols, in particular, substituted by ethylene glycol or by their oligomers, and their ether derivatives having 4-10 carbon atoms. 7. The microemulsion according to claim 6, wherein the ether derivatives of ethylene glycol or its oligomers are selected from diethylene glycol butyl ether, ethylene glycol monoethyl ether, and ethylene glycol diethyl ether. 8. The microemulsion according to claim 1-7, wherein the monocarboxylic, possibly hydroxylated compounds are selected from carboxylic acid with 1 - 4 carbon atoms, and esters thereof prepared from C1 to C5 monoalcohols. 9. The microemulsion according to claim 8, wherein the monocarboxylic compounds are selected from the group consisting of formic, acetic, butyric, and lactic acids and their C1 to C6 alkyl esters in alkyl group, and n-butylformiat and ethyllactat. 10. The microemulsion according to claim 4, wherein the polycarboxylic compounds are dicarboxylic compounds and are further selected from the group consisting of dicarboxylic acids containing 3 to 6 carbon atoms, and esters thereof prepared from C1 to C5 monoalcohols. 11. The microemulsion according to claim 10, wherein the dicarboxylic compounds are selected from the group consisting of malonic acid, succinic acid, dialkyl malonate, preferably diethyl malonate, and dialkyl succinates, preferably dimethyl succinate. 12. The microemulsion according to claim 1-11, wherein the ketones are di-C1- C6 -alkyl ketones, preferably methylethylketone. 13. The microemulsion according to claim 1-12, wherein the lactones comprise a lactone containing up to 6 carbon atoms, preferably gamma-butylactone. 14. The microemulsion according to claim 1-13, wherein the combinations of surfactants and cosurfactants represent a combination of alkyl phosphoric ester where alkyl radical contains at most 6 carbon atoms and which contains no more than three ethoxy groups, with the mixture of at least two cosurfactants. 15. The microemulsion according to claim 1-14, wherein the combination of cosurfactants represents a mixture of a carboxylic acid with a compound of group, consisting of other, optionally hydroxylated carboxylic acids, and their esters thereof, mono- or polyalcohols and their ether derivatives, ketones or lactones. 16. The microemulsion according to claim 14, wherein the combinations are selected from the combinations of acetic acid-butanoic acid, acetic acid-ethyl lactate, acetic acidethanol, acetic acid-diethylene glycol butyl ether, acetic acid-methyl ethyl ketone and acetic acid-y-butyrolactone. 17. The microemulsion according to claim 1-14, wherein the combinations of cosurfactants represents mixture of at least one ether of ethylene glycol, preferably of diethylene glycol butyl ether with an alkanol, a ketone, such as methyl ethyl ketone, or a monocarboxylic acid ester. 18. The microemulsion according to claim 1-14, wherein the cosurfactant combinations are a mixture of at least one ester of a dicarboxylic acid, such as alkyl-succinates ot alkyl malonates with an alkanol or a ketone. 19. The microemulsion according to claim 18, wherein the combinations are selected from the groups consisting of dimethyl succinate-ethanol and dimethyl succinate-methyl ethyl ketone.