baber/WOPTO huggingface dataset:
Patent CY-1124486-T1 (CY)
Title: Υποκατεστημενα βενζαμιδια 1,3-θειαζολ-2-υλιου
Inventor: DAVENPORT ADAM JAMES
IPC: C07D417/12
Filed: 2021-08-20
Abstract: Η παρούσα εφεύρεση αναφέρεται σε ενώσεις υποκατεστημένου βενζαμιδίου 1,3-θειαζολ-2-υλίου του γενικού τύπου (Ι) όπως περιγράφονται και ορίζονται στην παρούσα, σε φαρμακευτικές συνθέσεις και συνδυασμούς που περιλαμβάνουν τις εν λόγω ενώσεις και στη χρήση των εν λόγω ενώσεων για την παρασκευή μίας φαρμακευτικής σύνθεσης για τη θεραπευτική αντιμετώπιση ή προφύλαξη από μία πάθηση, συγκεκριμένα από νευρογενή διαταραχή, ως ένας μοναδικός παράγοντας ή σε συνδυασμό με άλλα δραστικά συστατικά.
Patent HR-P20120310-T1 (HR)
Inventor: KAZUMI KONDO
IPC: A61P9/00
Filed: 2012-04-10
Abstract: Spoj benzazepina, naznačen time, da je predstavljen općom formulom (1) gdje: R1 je peptidni ostatak opcijski zaštićen s jednom ili više zaštitnih skupina; ili njegova sol. Patent sadrži još 4 patentna zahtjeva.
Patent HR-P20120621-T1 (HR)
Inventor: JOHN D LAMBRIS
IPC: C07K7/08
Filed: 2012-07-30
Abstract: Spoj koji inhibira aktivaciju komplementa, sadr·i peptid sa sekvencom: Xaa1 - Cys - Val - Xaa2 - Gln - Asp - Xaa3 - Gly - Xaa4 - His - Arg - Cys - Xaa5 (SEQ ID NO:26); gdje: Xaa1 je Ile, Val, Leu, Ac-Ile, Ac-Val, Ac-Leu ili dipeptid Gly-Ile; Xaa2 je Trp ili njegov analog, gdje analog od Trp ima pojačan hidrofobni karakter u odnosu na Trp i odabire se između halogeniranog triptofana, 5-metoksitriptofana, 5-metiltriptofan i 1-metiltriptofana, uz uvjet da ako Xaa3 je Trp, Xaa2 je analog od Trp; Xaa3 je Trp ili njegov analog gdje je vodik u indolu zamijenjen atomom fluora čime je pojačan potencijal vodikove veze indolnog prstena; Xaa4 je His, Ala, Phe ili Trp; Xaa5 je L-Thr, D-Thr, Ile, Val, Gly, dipeptid Thr-Asn ili Thr-Ala ili tripeptid Thr-Ala-Asn, gdje je na karboksi krajnjem -OH bilo koji od L-Thr, D-Thr, Ile, Val, Gly ili Asn po izboru zamijenjen s -NH2; idva ostatka Cys povezana su disulfidnom vezom. Patent sadr·i jo® 17 patentnih zahtjeva.
Patent HR-P20150437-T1 (HR)
Title: Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer
Inventor: SAWYERS CHARLES L
IPC: C07D403/10
Filed: 2015-04-21
Abstract: The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
Patent SI-1090653-T1 (SI)
Title: Single-use injection device
Inventor: BRUNEL MARC
IPC: A61M/
Filed: 2000-09-15
Abstract: A single-use device for injection comprises: (1) a syringe, provided with a front nose and supporting an injection needle and having a rear collar; and (2) a device for protection of the injection needle of the syringe after use comprising a protective sheath consisting of rear and front bodies to be rendered integral, and a ring, having a mechanism for locking the syringe, accommodated in the rear body. A single-use device for injection comprises: (a) a syringe (1) provided with a front nose (1a) supporting an injection needle (2) and having a rear collar (1b); and (b) a protection device for protection after the syringe has been used. The syringe delimits a chamber which is filled with a dose of fluid to be injected and is sealed by a piston (4) which is rendered integral with one of the ends of a piston rod (5) provided with a thruster (6) at its opposite end. The protection device comprises a protective sheath (7) and a ring (24). The sheath consists of front and rear tubular bodies (8, 9) provided with an assembly mechanism which makes it possible to render the bodies integral to one in the extension of the other. The front body (8) has a diameter which is conjugated relative to that of the syringe and a length designed to accommodate the syringe partially. The rear body (9) has a diameter which is larger than that of the collar of the syringe body and comprises finger-support units (23). The ring is disposed in the rear body which comprises a mechanism (29, 31) for locking the collar. This makes it possible to introduce the syringe by presenting the needle opposite the rear body of the protective sheath. The ring and the rear body comprise: (i) a first mechanism (20, 22, 27) for relative locking in translation, which can make it possible to introduce the ring in the rear body, by presenting the ring opposite the surface of the assembly of the of the latter with the front body, and defining a first locking position (the position for injection) which allows injection to take place when the device for injection has been assembled; and (ii) a second mechanism (20, 22, 28) for relative locking in translation, which defines a second locking position (the position after use) which is obtained after rearward sliding of the ring inside the rear body in which the injection needle is accommodated in the front body. The ring and the front body is provided with a stop mechanism which keeps a resilient mechanism (42) compressed in the first locking position, for injection. The ring or the rear body comprises a rear portion which is radially deformable, and supporting the first locking mechanism in translation. This portion is designed to be deformed by the thruster (6) of the piston rod (5) at the end of the path of the latter so as to release the first locking units and to permit displacement of the ring towards its second locking position, for protection after use.
Patent SI-1385514-T1 (SI)
Title: Spiroindene and spiroindane compounds
Inventor: GOEHRING RICHARD R
IPC: A61K31/00
Filed: 2002-04-18
Abstract: A compound of the formula (I), wherein Z, A, B, C, R 1 , R 2 , X 1 , X 2 , Q and n are disclosed herein.
Patent SI-1718322-T1 (SI)
Title: Synergistic compositions with fk-228
Inventor: NAOE YOSHINORI
IPC: A61K31/122
Filed: 2005-02-25
Abstract: An antitumor agent containing, in combination, at least one kind of antitumor agent selected from the group consisting of an antitumor agent that forms a cross-link with DNA and shows an antitumor effect, an antimetabolite antitumor agent and a taxane antitumor agent, and a histone deacetylase inhibitor. According to the present invention, an antitumor agent causing reduced side effects and having a superior antitumor activity can be provided.
Patent SI-1880829-T1 (SI)
Title: Whole surface welded anti-slip coatings on plastic man holes (profiled strips and plastic granulates)
Inventor: PREDL MANFRED
IPC: B29C65/00
Filed: 2006-07-19
Abstract: The deep drawing process produces a gripping bridge for a shaft bottom from plastic granulate (3), which is applied to the side intended to face the concrete during the thermal plastic deformation of the shaft bottom half-part (1), making use of the process heat of the deep drawing process, and is welded to the surface of the shaft bottom half part by this means.
Patent SI-1866379-T1 (SI)
Title: Adsorbents comprising anthraquinone dye-ligands for the separation of biological materials
Inventor: EKKUNDI VADIRAJ SUBBANNA
IPC: C09B1/00
Filed: 2006-03-29
Abstract: A process for the separation of biological materials, such as dye-ligand affinity chromatography, wherein an adsorbent is used, which comprises a reaction product of certain reactive anthroquinone compounds and a substrate having a group capable of reaction with a reactive group in said reactive anthroquinone compounds to form a covalent bond.
Patent SI-1924252-T1 (SI)
Title: Method for improving cell permeability to foreign particles
Inventor: SHAH JYOTSANA S
IPC: A61K47/16
Filed: 2006-07-27
Abstract: The present invention provides a method for allowing foreign particles to penetrate, very efficiently, the cell wall, cell membrane, organelle membrane and/or nuclear membrane of a cell and hybridizing or binding to the complimentary target in the cell. The cells may be from a culture or from specimens obtained from a patient. The foreign particle can be a probe consisting of, for example, either individually or in any combination of two or more of the following: DNA, RNA, peptide nucleic acids (PNA), glycopeptides, lipopeptides, glycolipids or prions. The target is a cell, a cell component or, preferably, a pathogen or pathogen component. The pathogen can be, for example, bacteria, fungi, yeast or viruses.
Patent SI-2918604-T1 (SI)
Title: Treatment of pediatric acute lymphoblastic leukemia
Inventor: ZUGMAIER GERHARD
IPC: C07K16/00
Filed: 2009-11-06
Abstract: The present invention relates to a method for the treatment, amelioration or elimination of pediatric acute lymphoblastic leukemia (ALL), the method comprising the administration of a pharmaceutical composition comprising a CD19×CD3 bispecific single chain antibody construct to a pediatric ALL patient in the need thereof.
Patent DE-3587892-T2 (DE)
Inventor: SARNOFF JAY
IPC: A61N1/375
Filed: 1985-05-29
Granted: 1994-11-10
Abstract: A method of treating a patient with liquid medicament under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable, including the treatment of individuals undergoing heart attack symptoms with t-PA. The method comprises the steps of injecting the liquid medicament t-PA preferably with a blood absorption enhancing agent such as hydroxylamine hydrochloride into the muscle tissue of the patient, applying to the patient which has received the injection repeated blood flow stimulating cycles, each of which includes a period of electrical stimulus during which the muscle tissue which has received the injection tenses followed by a period of no electrical stimulus during which the muscle tissue which received the injection is allowed to relax inducing enhanced blood flow within the muscle tissue, and continuing the application of the repeated blood flow stimulating cycles until the injected liquid medicament has been sufficiently absorbed into the enhanced blood flow to achieve a desired possible patient response of reperfusion and apparatus for carrying out the method.
Patent DE-3686048-T2 (DE)
Inventor: HWO CHARLES C
IPC: C08L23/14
Filed: 1986-11-21
Granted: 1993-01-28
Abstract: A blend suitable for use in producing heat shrinkable, thermoplastic films of good clarity and good processability, comprises a mixture containing (i) 10 to 60% by weight of a butene-1/propylene copolymer, wherein the propylene comonomer content is from 5 to 40 mole percent, and (ii) 40 to 90% by weight of a propylene homopolymer or copolymer.
Patent DE-3688823-T2 (DE)
Inventor: CLAESSON JON
IPC: G01F17/00
Filed: 1986-04-30
Granted: 1994-01-20
Abstract: PCT No. PCT/NO86/00034 Sec. 371 Date Dec. 23, 1986 Sec. 102(e) Date Dec. 23, 1986 PCT Filed Apr. 30, 1986 PCT Pub. No. WO86/06473 PCT Pub. Date Nov. 6, 1986.A method for three dimensional measurement of objects being conveyed through or moved relative to a measurement frame for, by incremental measurements of height, width and length of the object to calculate cubical and circumscribed volume of the object. Each transmitter/receiver element pair of the measurement frame is calibrated by controlling the amount of the light emitted from the transmitter and the threshold level of the receiver, such that the signal/noise ratio of the receiver lies above a specific limit, simultaneously with the illumination time being kept the shortest possible. By incremental measurements at least one pair consisting of transmitter element and directly opposite receiver element in the measurement frame is activated at time, and an external signal being a function of the movement of the object relative to the measurement frame is compared with the registered signals from the receiver elements for calculation of the volumes. The measurement frame is constructed in the form of horizontal and vertical transmitter- and receiver modules consisting of the transmitter elements and receiver element respectively. A computer is connected to the measurement frame for calibration of the respective transmitter- and receiver elements of the measurement frame and for calculation of the volumes being derived as a result of shadow images of the object on the receiver elements. A display is associated with the computer for display of the volume magnitude of the object. Utilization for e.g. calculation of freight charges of objects.
Patent DE-3786334-T2 (DE)
Inventor: KATZ DAVID
IPC: A61K47/48
Filed: 1987-02-02
Granted: 1993-12-02
Abstract: Receptor blocking technology using proteins conjugated to polymers of D-glutamic acid and D-lysine for treatment of antibody-mediated autoimmune disease, membrane and tumour disorders.
Patent DE-3788867-T2 (DE)
Inventor: TURNER MICHAEL NEIL
IPC: H04B7/26
Filed: 1987-12-04
Granted: 1994-05-11
Abstract: A repeater for enhancing performance in poor signal areas has a bank of frequency-agile, single channel amplifiers (13), and monitoring and control means (14, 16). The monitoring means (14) scans the channels of the band and, upon identifying a channel carrying traffic, enables one of the amplifier units (13) to operate on that channel.
Patent DE-3878921-T2 (DE)
Inventor: PROUST STEPHANE
IPC: B62C1/00
Filed: 1988-12-23
Granted: 1993-06-17
Abstract: PCT No. PCT/FR88/00638 Sec. 371 Date Jun. 22, 1990 Sec. 102(e) Date Jun. 22, 1990 PCT Filed Dec. 23, 1988 PCT Pub. No. WO89/05748 PCT Pub. Date Jun. 29, 1989.A hitch for a horse-drawn vehicle, which includes a single shaft (2) passing over a horse's back and connected at its front end to a harness (5, 6, 7) via a traction cradle (4) on which the single shaft (2) is rotatably mounted, and at its rear end to a horse-drawn vehicle (3). The cradle (4) comprises two arcuate frame members (9, 10) interconnected at their bottom ends for connection with a collar (5) to the harness and diverging progressively from each other to reach a maximum separation vertically above the horse's withers. An element (11) integral with the single shaft (2) is rotatably mounted on a member (12) interconnecting the two frame members (9, 10) at their point of maximum separation. The cradle rests on the horse's back via two pads (15, 16) swivel-mounted on the rear frame member (10) and situated on either side of the midline of the horse's back. The single shaft (2) carried by the cradle (4) is connected to a wheeled vehicle (3) via a shock absorber suspension.
Patent DE-3879146-T2 (DE)
Inventor: NAKANISHI TAKASUKE
IPC: A61C1/14
Filed: 1988-12-28
Granted: 1993-06-17
Abstract: A chuck device for a dental handpiece (10) includes a dental bur (11), a sleeve (14, 114) for accommodating and attaching the dental bur (11), a push button (20) for detaching the dental bur (11), and a connecting-removal unit (18, 118) for removably holding and securing the dental bur (11) within the sleeve (14, 114). The connecting-removal unit (18, 118) includes an elastic engagement member (18a, 118a, 70) normally engaging with an engaging projection (11b) of the dental bur (11) for securing the dental bur (11) within the sleeve (14, 114), and an opening (18b) for accommodating the elastic engagement member (18a) within the sleeve (14) or an upper sleeve portion (114d) for fitting the elastic engagement member (118a, 70) on the outer side of the sleeve (114). The elastic engagement member (18a, 118a, 70) has a slit (18a-i, 118a-i) and can be extended apart. When the push button (20) is pushed downwards, the cam surface (20a) of the push button abuts on and extends the elastic engagement member (18a, 118a, 70) apart to release the engagement between the elastic engagement member and the engaging projection (11b) of the dental bur (11) to detach the dental bur (11) from the sleeve (14, 114).
Patent DE-3887140-T2 (DE)
Inventor: OCCHIONERO MARC
IPC: B22F3/22
Filed: 1988-04-11
Granted: 1994-04-28
Abstract: A process for forming articles from inorganic sinterable particulates includes providing a well-dispersed, low pressure injectable slurry, freeze-forming the slurry into a desired geometry, and drying the piece so formed by a predominantly sublimative process, to produce a green article that can be conventionally sintered. The slurries preferably have a solids content of at least about 35 v/o, a viscosity of preferably not more than about 1000 cP at 100 s<-1>, and are preferably injectable at not more than about 1000 psi.
Patent DE-3887416-T2 (DE)
Inventor: LANDLER YVAN
IPC: C08J5/06
Filed: 1988-08-10
Granted: 1994-08-04
Abstract: Composite material comprising a matrix (1) consisting of a semicrystalline polyolefin homopolymer or copolymer of any molecular mass, a reinforcement (2) consisting of textile materials, including metallic ones, coated with an adhesiveness-promoting layer (3) comprising at least one elastomeric component and intimately bonded to the polyolefin matrix (1) by means of a thin coating (5) of the reinforcement made adhesive by a polyolefin with a number-average molecular mass of at least 500,000. 
<??>Process for producing such a composite.
Patent TR-199900293-T2 (TR)
Inventor: GEROLYMATOS PANAYOTIS NIKOLAS
IPC: A61K31/714
Filed: 1997-08-08
Abstract: Alzheimer hastaligi tedavisi için bir farmasötik bilesim üretmek üzere selat maddesi clioquinol'ün kullanimi ile ilgilidir.
Patent DE-60001675-T2 (DE)
Inventor: FOGAGNOLO ARMANDO
IPC: A47J31/44
Filed: 2000-09-25
Granted: 2003-11-13
Abstract: An espresso coffee making machine, comprising a bearing structure formed by a monolithic cradle (2), made of plastic material and equipped with fastening means and/or compartments for housing a water heating boiler, a compression and pumping group, possibly other internal components, and with a basin for collecting liquids, and by a metal frame (4) that is coupled to the monolithic cradle (2) and is arranged to support one or more coffee delivery groups, the electric and hydraulic control members of the machine and a plurality of external covering panels (28, 32, 34, 35, 36, 30) of plastics and/or metal.
Patent DE-60013389-T2 (DE)
Inventor: MASSACCESI GIANNI
IPC: B60K17/04
Filed: 2000-12-11
Granted: 2005-09-15
Abstract: A motor wheel for driving the driving wheel of an industrial vehicle and the like, comprising, upstream of a two-stage rotary-ring reduction unit (2), a gearbox (3) with fixed-ring epicyclic gear train, with at least two positions which respectively correspond to the high or travel speed and to the low or working speed. A parking brake (41) is further provided downstream of the gearbox (3) with respect to the motion input. <IMAGE>
Patent DE-60016566-T2 (DE)
Inventor: CARLING ROBERT
IPC: A61P25/06
Filed: 2000-01-19
Granted: 2005-12-15
Abstract: A class of substituted 1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a difluoro- or trifluoro-substituted phenyl ring at the 3-position, a triazolyl-methoxy moiety at the 6-position, and a tert-butyl group at the 7-position, are selective ligands for GABAA receptors, in particular having high affinity for alpha2 and/or alpha3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
Patent DE-60027223-T2 (DE)
Inventor: FUJIWARA TAKAYUKI
IPC: B65H23/16
Filed: 2000-06-21
Granted: 2006-08-31
Abstract: A film winding apparatus has a film winding mechanism (50) for rotating a roll core (28) to wind an elongate film (24) around the roll core (28) thereby to produce a film roll (30), a product receiving mechanism (52) for gripping the film roll (30) while tensioning the elongate film (24), the product receiving mechanism (52) being displaceable away from the film winding mechanism (50), and a cutting mechanism (54) for transversely cutting off the elongate film (24) while the elongate film (24) is being tensioned by the product receiving mechanism (52). The elongate film (24) can be wound highly accurately around the roll core (28) with a simple process and arrangement.
Patent DE-60030286-T2 (DE)
Inventor: MCBRIDE KEVIN
IPC: C12Q1/02
Filed: 2000-06-30
Granted: 2007-08-30
Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter ("lux box") or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
Patent DE-60038496-T2 (DE)
Inventor: JOBLING STEPHEN ALAN
IPC: A23L29/20
Filed: 2000-09-13
Granted: 2008-12-24
Abstract: Disclosed is potato starch which, when in native form extracted from a potato plant, exhibits freeze/thaw stability such that a 1 %w/v aqueous suspension of the starch has an absorbance at 700nm wavelength of less than 1.2 units following 4 freeze/thaw cycles of freezing at -70  DEG C overnight and thawing at room temperature for at least 2 hours; together with a method of altering the starch content of a plant; and altered plants, especially altered plants which contain freeze/thaw stable starch. Further disclosed is waxy (i.e. low amylose) starch having reduced gelatinization onset and swelling temperatures.
Patent DE-60100951-T2 (DE)
Inventor: BIGI MAURIZIO
IPC: B60W30/18
Filed: 2001-04-10
Granted: 2004-07-29
Abstract: The electric actuator, for the control of the clutch and/or sequential gearbox in motor vehicles, comprises an electric motor (11) and a mechanism (9, 10, 31, 32) for transforming rotary motion into linear motion of the actuator element (2, 22, 33, 52, 67), and has a thrust crank or at least one cam (9, 29, 50) that performs a complete rotation returning to its starting position, whether it be the control for the clutch (1, 48), the gearbox (27, 47), or both. Also, the said cam is advantageously made in the form of a template (9, 29, 50), fashioned in a plate (8, 21, 28, 49, 68) sliding in a guide (14, 30, 69), in which a crank stud (10) is positioned rotating with the action of the said electric motor (11, 45). The said template (9) for operating the clutch being advantageously shaped in accordance with the specific requirements of the application (R, D, F, I) to optimise the loads. Combined, compact embodiments of the two actuators (47, 48) for the clutch and sequential gearbox are comprised, as well as: mechanical disconnecting safety mechanisms (53, 60) for operation of the gearbox lever; sensing devices (71) for measuring the actuator forces for the clutch; finally, a locking mechanism (78, 79, 80) to keep the clutch disengaged during multiple gear changes in quick succession.
Patent DE-60106242-T2 (DE)
Inventor: SORRENTINO FRANCOIS
IPC: C04B5/06
Filed: 2001-05-22
Granted: 2006-02-23
Abstract: A treatment method includes injecting oxygen into the liquid steel works slag, adding and dissolving in the slag alumina and lime sources, and optionally silica and iron sources and cooling the slag until solidification, the additions being carried out in such amounts and the cooling being performed at such speed that the resulting slag has a mineralogical composition having one of the following constituting element: (a) an amorphous glassy phase; (b) a first group of phases (1) consisting, in weight percentages, of 10-40 CA, 20-50 C2AS, 30-50 C6AF2 and 10-30 C2S; (c) a second group of phases (2) consisting, in weight percentages, of 20-40 C2F, 10-30 C2AS, 20-50 C6AF2 and 10-40 C2S, and (d) a mixture of amorphous glassy phase and of the first or second group of phases. The invention is applicable to hydraulic binders.
Patent DE-60108122-T2 (DE)
Inventor: BUONONATO ANTONIETTA
IPC: A23L33/15
Filed: 2001-04-24
Granted: 2005-12-29
Abstract: Double fumarates of L-carnitine or isovaleryl L-carnitine and an amino acid are disclosed which are useful as active ingredients of food supplements, dietary supplements or drugs.