Patent SG-11201806782Q-A (SG)
Title: Promoter
Inventor: CAWOOD RYAN
IPC: C12N15/85
Filed: 2017-02-28
Abstract: Figure12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 1111111101111011101010111110101111101110101fil01011110101111111011110111111 International Bureau (10) International Publication Number (43) International Publication Date WO 2017/149292 Al 8 September 2017 (08.09.2017) WIP0 I PCT (51) International Patent Classification: C12N 15/85 (2006.01) C07K 14/47 (2006.01) (21) International Application Number: PCT/GB2017/050537 (22) International Filing Date: 28 February 2017 (28.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1603577.6 1 March 2016 (01.03.2016) GB (71) Applicant: OXFORD GENETICS LIMITED [GB/GB]; First Floor, Medawar 1, Robert Robinson Avenue, The Ox- ford Science Park, Oxford Oxfordshire OX4 4GA (GB). (72) Inventors: CAWOOD, Ryan; c/o Oxford Genetics Lim- ited, First Floor, Medawar 1, Robert Robinson Avenue, The Oxford Science Park, Oxford Oxfordshire OX4 4GA (GB). PARKER-MANUEL, Richard; c/o Oxford Genet- ics Limited, First Floor, Medawar 1, Robert Robinson Av- enue, The Oxford Science Park, Oxford Oxfordshire OX4 4GA (GB). (74) Agent: DEHNS; St Bride's House, 10 Salisbury Square, London Greater London EC4Y 8JD (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, [Continued on next page] W O 20 17 / 149 29 2 Al (54) Title: PROMOTER Relative Light Units rd p568 FerH HSVtk SVMI Ubiquitin RSV SFFV CHEF E1A RSV EF1-Alpha Grp78 CMV-Beta-Globin CAG p565 CMV p567 p576 (57) : The present invention relates to nucleic acid molecules which are capable of promoting transcription of operably-linked hetero - logous polynucleotides in mammalian ceils. The invention also relates to expression vectors and host ceils which comprise the nucleic acid molecules of the invention. Such expression vectors may be used to pro- duce recombinant proteins, e.g. antibodies and lentiviral polypeptides. WO 2017/149292 Al 1#110HOMMIONOIDEMOMOMIENHOINOVOIMIE KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a))