baber/WOPTO huggingface dataset:
Patent NZ-521322-A (NZ)
Title: Use of a synergistic combination product comprising nonsteroidal antiandrogen and an epidermal growth factor receptor tyrosine kinase inhibitor to treat or prevent prostate cancer
Inventor: FURR BARRINGTON JOHN ALBERT
IPC: A61K31/167
Filed: 2001-04-03
Abstract: A combination therapeutic product is described comprising a non-steroidal antiandrogen and an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) for use simultaneously, sequentially or separately in the synergistic treatment or prophylaxis of prostate cancer. In particular, the product is effective in inhibiting the transformation of prostate cancer cells from a hormone-dependent state into a hormone-independent state. It is further expected that the therapeutic product will have a beneficial effect in preventing the onset of prostate cancer in men genetically predisposed to the disease.
Patent NZ-521631-A (NZ)
Title: Drug combination for the treatment of headache comprising a non-steroidal anti-inflammatory drug
Inventor: NICKOLSON VICTOR JOHANNES
IPC: A61K31/192
Filed: 2001-04-04
Abstract: A composition having the combination comprising paracetamol or a non-steroidal anti-inflammatory drug (NSAID) and another drug, wherein the other drug is mirtazapine; the use of the composition in the manufacture of a medicament for the treatment of headache such as tension-type headache
Patent NZ-524960-A (NZ)
Title: Air samplers
Inventor: SQUIRRELL DAVID JAMES
IPC: G01N1/24
Filed: 2001-10-01
Abstract: With reference to FIG. 1, and air sampler 1 for use in analysing biological or other analytes, comprises an airflow chamber 2 having an air inlet 3 and an air outlet 4. An extract from 5, draws ambient air in through the inlet 3, and then through the chamber 2, to discharge it back to atmosphere by way of an outlet 6. The airflow chamber 2 houses a cyclone air/liquid separator 7 through which the inflowing air is caused to pass. An injector 8 introduces liquid into air flowing through the air inlet 3. The cyclone separator 7 extracts this liquid and any entrained particles therein and discharges it from the airflow chamber 2, initially by way of a duct 9, where it is then conveyed to a collection vessel 12, by way of a three channel peristaltic pump 13, and a duct 14. The collection vessel 12 is housed within a Peltier-cooled holder 15 to maintain the contents of the vessel 12 within the 2 C.-8 C. range which is desirable for maintaining the integrity of biological analytes such as bacteria or proteins. Analyses such as PCR, culture on agar plates or immunoassays may be performed on the collected samples. The holder 15 also houses sample bottles 16, 17, 18 and 19.
Patent NZ-528730-A (NZ)
Title: Single phase or polyphase switchgear in an enveloping housing
Inventor: LAMMERS AREND JAN WILLEM
IPC: H02B13/055
Filed: 2002-04-09
Abstract: Single phase or polyphase switchgear comprises one or more switches which are mounted with the aid of solid insulation such that they are insulated, as well as associated live components such as rail systems and connectors, wherein both the switches and the associated live components are housed in a housing enveloping (7) the switches and live components, in which the enveloping housing is filled with air having a low moisture content and the interior space thereof is sealed with respect to the exterior space around the enveloping housing in such a way that the air present in the housing is not contaminated and will not reach the dew point, characterised in that a moisture-absorbent agent (33) is arranged in the enveloping housing (7), the quantity of the moisture-absorbent agent (33) being such that the moisture that penetrates as a result of leakage of the enveloping housing (7) is absorbed during the life of the switchgear.
Patent NZ-533884-A (NZ)
Title: Routing method and routing system with conditional logging
Inventor: MEIER HERBERT
IPC: H04L12/24
Filed: 2002-09-12
Abstract: A routing method for messages (10) in a communication network (12), with a transmitting entity, at least one target entity (24), a forwarding mechanism (16) that provides network applicable addressing of at least one of the target entities, a logging mechanism (18) that serves to buffer messages in at least one log file (20) comprises forwarding messages from the transmitting entity by means of the forwarding mechanism to its entity, or temporarily buffering the messages by means of the logging mechanism whenever the messages cannot be forwarded to at least one of the target entities of the forwarding mechanism.
Patent NZ-534028-A (NZ)
Title: A system for secure distribution of electronic content and collection of fees
Inventor: WILSON ERIC
IPC: G06Q30/06
Filed: 2002-12-10
Abstract: A system and method for the secure distribution of electronic content, particularly electronic documents, using primarily remote display protocols is disclosed. One or more presentation subsystems retrieve electronic content from repositories, reformat the content and render the content for display according to a users' equipment and preferences. A management subsystem checks associated business models (such as fees, access limits, credit rating) to determine viewing conditions for the user of the electronic content. The system and method provide an automated secure mechanism for remote access to electronic content.
Patent NZ-535761-A (NZ)
Title: Iron dextrin compounds for the treatment of iron deficiency anaemia
Inventor: ANDREASEN HANS BERG
IPC: A61K47/12
Filed: 2003-04-08
Abstract: Disclosed herein is an Iron dextrin compound and a process for preparing said compound consisting of hydrogenated dextrin in stable association with ferric oxohydroxide, characterised in that, said hydrogenated dextrin has a weight average molecular weight equal to or less than 3,000 Daltons and a number average molecular weight higher than or equal to 400 Daltons. Also disclosed is a pharmaceutical composition that comprises said iron dextrin compound for the treatment or prophylaxis of iron deficiency anaemia in an animal or a human subject, wherein the therapeutic composition is prepared for parenteral or oral administration.
Patent NZ-536656-A (NZ)
Title: Recreational apparatus
Inventor: BRINSLEY ANDREW WINSTON
Filed: 2004-11-18
Abstract: A recreational apparatus comprising: a support cable assembly, having one or more support cables, that is secured so as to extend across a void; a passenger carriage for one or more passengers that is supported by the support cable assembly; a positioning system associated with the passenger carriage that is operable to raise and lower the passenger carriage between a lowered position toward or at a base area of the void and a raised position above the base area; and a descent apparatus that is securable to a part of the apparatus to enable a passenger to perform a descent-based activity. The secured descent apparatus is accessible from the passenger carriage when the passenger carriage is in the raised position. The descent apparatus is further arranged to be fastened to a passenger or passengers to enable the passenger(s) to descend from the passenger carriage into the void when the passenger carriage is in the raised position.
Patent NZ-536848-A (NZ)
Title: Preparation of 1,2,4-triazolylmethyloxiranes
Inventor: NOACK RAINER
Filed: 2003-06-06
Abstract: A method for the production of 1,2,4-triazol-1-yl-methyl-oxiranes of formula (I) is disclosed, wherein A and B are the same or different and independently represent C1-C4-alkyl, phenyl-C1-C2-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl, tetrahydropyranyl, tetrahydrofuranyl, dioxanyl or phenyl, wherein the phenyl radical can contain 1 to 3 substituents selected form the group: halogen, nitro, C1-C4-alkyl, C1-C4-alkyloxy, phenoxy, amino, C1-C2-halogenalkyl or phenylsulfonyl, wherein the method comprises: (a) reacting an oxirane of formula (II) wherein A and B have the above mentioned meaning and L represents a nucleophilically substitutable leaving group, with 4-amino-1,2,4-triazole of formula (III), to form 4-amino-1,2,4-triazolium salts of formula (IV), and (b) deaminating the 4-amino-1,2,4-triazolium salts (IV) with alkali metal nitrites and acid or organic nitrites to obtain 1,2,4-triazol-1-yl-methyl-oxiranes of formula (I).
Patent NZ-539663-A (NZ)
Title: Non-invasively measuring hemodynamic parameters
Inventor: HESSEL STEPHEN R
IPC: A61B5/021
Filed: 2003-10-10
Abstract: Improved apparatus (100) and methods for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. The apparatus is adapted to accurately place and maintain a sensor (101) (e.g., tonometric pressure sensor) with respect to the anatomy of the subject, including an alignment apparatus (230) which is separable from an adjustable fixture (257). The alignment apparatus moveably captures the sensor to, inter alia, facilitate coupling thereof to an actuator (106) used to position the sensor during measurements. The alignment apparatus also advantageously allows the sensor position to be maintained when the fixture (100) is removed from the subject, such as during patient transport. Methods for positioning the alignment apparatus and sensor, correcting for hydrostatic pressure effects, and providing treatment to the subject are also disclosed.
Patent NZ-541187-A (NZ)
Title: Use of a combination containing a non-nucleoside reverse transcriptase inhibitor (NNRTI) with an inhibitor of cytochrome P450, such as protease inhibitors
Inventor: CORDINGLEY MICHAEL G
IPC: A61K36/752
Filed: 2003-12-15
Abstract: A combination of a therapeutically effective amount of the compound of formula (I) or a pharmaceutically acceptable salt thereof and an amount of ritonavir or a pharmaceutically acceptable salt thereof, which is effective to improve the pharmacokinetics of the compound of formula (I) is disclosed. These combinations are suitable for use in the manufacture of a medicament for the prophylaxis or treatment of HIV infection.
Patent NZ-545111-A (NZ)
Title: Aquatic vegetation control apparatus and method
Inventor: COSTAIN ROGER MELVYN
Filed: 2006-02-03
Abstract: Aquatic vegetation gathering apparatus for use in control of weeds or other vegetation in lakes and rivers and a method for controlling aquatic vegetation are disclosed. The apparatus has a floatable storage device (73), a pump to transport water and vegetation to the storage device through ducting (89), and a diver monitoring station (93). The storage device collects and stores vegetation while allowing the water to drain out. The ducting can be manipulated by a diver (90) to control the collection of vegetation into an inlet, while an attendant monitors the diver from the monitoring station. A mesh fence or enclosure (77) is used to encompass an area of water and define an isolation zone from which vegetation is to be collected.
Patent NZ-545393-A (NZ)
Title: 2-Alkylidene-19-nor-vitamin D derivatives for the treatment of osteopenia or male osteoporosis
Inventor: CAMPAGNARI JUDITH LEE
IPC: A61K31/59
Filed: 2004-09-06
Abstract: The disclosure relates to specific 2¡alkylidene-19-nor-vitamin D derivative that are suitable for treating osteopenia, and examples of preparing such vitamin D derivatives. Particularly disclosed is the use of a therapeutically effective amount of 2-methylene-19-nor-20 (S)-1alpha,25-dihydroxy vitamin D3 in the preparation of a medicament for treating osteopenia.
Patent NZ-554775-A (NZ)
Title: Method, Computer Program Product And Arrangement For Controlling The Milking By A Milking Machine
Inventor: PETTERSON TORBJORN
IPC: A01J/
Filed: 2005-12-13
Abstract: A method for controlling the milking by a milking machine is disclosed. The method includes: - storing, in a processing and control device, a plurality of different milking schemes, each of which being distinguished by a set of milking parameters; - controlling, by the processing and control device, the milking machine for the milking of a milking animal so that each of the different milking schemes is applied for at least one milking of the milking animal; - for each of the milkings, recording, by the processing and control device, a milk yield and/or a milking time of the milking animal; - evaluating, by the processing and control device, each of the different milking schemes for milking the milking animal based on at least the recorded milk yield and/or the milking time; - selecting, by the processing and control device, one of the different milking schemes based on the evaluation; and - controlling, by the processing and control device, the milking machine during subsequent milkings of the milking animal so that the subsequent milkings are performed according to the selected milking scheme.
Patent NZ-556667-A (NZ)
Title: Amorphous lercanidipine hydrochloride
Inventor: LEONARDI AMEDEO
IPC: A61K31/435
Filed: 2006-02-24
Abstract: Disclosed is a pharmaceutical composition including amorphous lercanidipine (methyl 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) pyridine-3,5-dicarboxylate) hydrochloride having a purity of at least 95% and containing less than 0.5% of crystalline lercanidipine hydrochloride and a pharmaceutically acceptable diluent, carrier and/or excipient. Also disclosed is the use of amorphous lercanidipine hydrochloride having a purity of at least 95% and containing less than 0.5% of crystalline lercanidipine hydrocholoride for the preparation of a medicament for the treatment of hypertension.
Patent NZ-556774-A (NZ)
Title: Syrup composition comprising dexibuprofen as an active ingredient and method for the preparation thereof
Inventor: WOO JONG SOO
IPC: A61K9/08
Filed: 2006-01-03
Abstract: Disclosed is a glycerin-free dexibuprofen syrup composition comprising: 0.1 to 10 w/v percent of dexibuprofen ((S)-ibuprofen) having an average particle size ranging from 10 to 300 microns; 0.01 to 40 w/v percent of a viscosity controlling agent selected from the group consisting of D-sorbitol solution, agar, sodium alginate, povidone, polyethylene glycol, hydroxyethylene cellulose and a mixture thereof; 0.1 to 80 w/v percent of a sweetener selected from the group consisting of sugar, high fructose, stevioside, dipotassium glycirhyzinate and a mixture thereof; 0.01 to 10 w/v percent of a suspending agent; 0.01 to 5 w/v percent of an emulsifier; and 0.01 to 5 w/v percent of a pH controlling agent, said composition having a viscosity ranging from 500 to 3,000 cPs and pH ranging from 3.0 to 6.0. Also disclosed is a method to prepare said compostion.
Patent NZ-577127-A (NZ)
Title: Imidazotriazines and imidazopyrimidines as kinase inhibitors
Inventor: ZHOU JINCONG
IPC: A61K31/519
Filed: 2007-11-19
Abstract: Disclosed is a substituted bicyclic heterocyclic compound of formula (I) wherein the substituents are as disclosed in the description. Examples of compounds of formula (I) are: 2-Fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide; (1-Acetyl-4-{ 4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-1H-pyrazol-1-yl} piperidin-4-yl)acetonitrile and N-Ethyl-1-{ 4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]phenyl} cyclopropanecarboxamide. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and the use of a compounds of formula(I) in the manufacture of a medicament for treating cancer, atherosclerosis, lung fibrosis, renal fibrosis and regeneration, liver disease, allergic disorder, inflammatory disease, autoimmune disorder, cerebrovascular disease, cardiovascular disease, or condition associated with organ transplantation.
Patent NZ-586322-A (NZ)
Title: Method for programably treating water in a water cooler
Inventor: DAVIS KENNETH A
IPC: B67D7/76
Filed: 2005-04-21
Abstract: A method of sanitizing a water dispenser (10) is disclosed. The water dispenser has a cabinet (20) with a water supply that includes a reservoir (15) which is cooled by a refrigeration unit including a compressor (32) and has formed an ice ring in the reservoir and an operable spigot (90, 92) on the cabinet enables water to be dispensed from the cabinet and its water supply. The method comprises a) a programmable ozone generator, including a programmable controller (200), turning off power to the compressor; the programmable ozone generator injecting air into the reservoir to at least partially melt the ice ring; and the programmable ozone generator generating and injecting ozone into the reservoir via at least one diffuser element. The water dispenser further comprises a remote display (250) operably connected to the programmable controller but spaced apart from the programmable controller, and the method further comprises operating the remote display to display at least one indicator regarding operation of the programmable controller.
Patent NZ-589330-A (NZ)
Title: Interleukin-21 receptor binding proteins
Inventor: BLOOM LAIRD
IPC: C07K16/28
Filed: 2009-05-26
Abstract: Disclosed are binding proteins and antigen-binding fragments thereof that bind interleukin-21 receptor (IL-21R), in particular, human IL-21R, and their use in regulating IL-21R-assciated activities. The binding proteins disclosed are useful in treating and/or diagnosing IL-21R-associated disorders, such as inflammatory disorder, autoimmune disease, allergies, transplant rejection, hyperproliferative disorders of the blood, and other immune system disorders.
Patent NZ-595393-A (NZ)
Title: Methods and compositions for improving pregnancy outcome
Inventor: TREMELLEN KELTON PAUL
IPC: A61K31/01
Filed: 2006-07-05
Abstract: Disclosed is the use of: (i) an effective amount of at least one anti-oxidant agent; (ii) an effective amount of at least one agent that reduces inflammation in the male reproductive tract and/or increases testicular testosterone concentration; and (iii) an effective amount of at least one agent that improves sperm function and/or is involved in cellular DNA synthesis, wherein the at least one agent that reduces inflammation in the male reproductive tract and/or increases testicular testosterone concentration comprises about 1000 mg garlic for the manufacture of a medicament for treating infertility or reduced fertility in a male subject. Further disclosed is a composition for improving male reproductive health, comprising Vitamin E; Vitamin C, or a salt thereof; lycopene; selenium; zinc; and about 1000 mg garlic; or a pharmaceutically acceptable derivative of any of the aforementioned components; the composition optionally further comprising folic acid, or a salt thereof, and/or Co Enzyme Q10.
Patent NZ-596420-A (NZ)
Title: Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies
Inventor: VON FIGURA KURT
IPC: A61K38/00
Filed: 2004-02-10
Abstract: Provided is a method of producing an activated sulfatase comprising cultivating an isolated sulfatase-producing cell, wherein the cell expresses: (i) a sulfatase; and (ii) an over-expressed Formylglycine Generating Enzyme with a specified amino acid sequence wherein the ratio of active sulfatase to total sulfatase produced by the cell is increased by at least 5% over the ratio of active sulfatase to total sulfatase produced by the cell.
Patent NZ-598912-A (NZ)
Title: Spirolactam derivatives and uses of same
Inventor: DOLLER DARIO
IPC: A01N43/38
Filed: 2010-10-26
Abstract: 598912 Disclosed herein is a compound of formula I wherein the variables are defined in the specification, and the use thereof for the treatment of cognitive, neurodegenerative, psychiatric or neurological disease or disorder such as mood disorder, an anxiety, a schizophrenia, Alzheimer's disease, Parkinson's disease, multiple sclerosis, Huntington's chorea, amyotrophic lateral sclerosis, Creutzfeld-Jakob disease, a trauma-induced neurodegeneration, AIDS-induced encephalopathy, a non-AIDS-induced encephalopathy, Fragile X syndrome, an autism spectrum disorder, and a combination thereof. Additionally for the treatment of gastroesophageal reflux disease or disorder. Additionally for the treatment of alcohol dependence. Exemplary compounds include: pyridine-2-carboxylic acid [9-fluoro-2-(3-fluoro-phenyl)-9-methyl-1-oxo-2-aza-spiro[4.5]dec-7-yl]-amide; 2-methyl-pyrimidine-4-carboxylic acid [2-(3,5-difluoro-phenyl)-8-fluoro-1-oxo-2-aza-spiro[4.5]dec-7-yl]-amide; and 2-methyl-pyrimidine-4-carboxylic acid [2-(4-fluoro-phenyl)-4-hydroxy-4-methyl-1-oxo-2-aza-spiro[4.5]dec-7-yl]-amide.
Patent NZ-600069-A (NZ)
Title: Improved firing button for automatic injection device
Inventor: SHANG SHERWIN S
IPC: A61M5/20
Filed: 2010-12-15
Abstract: Disclosed is a firing button (32) for use in an automatic injection device (see figures 10A & 10B). The firing button comprises an outer portion for contact by a user of the automatic injection device to allow the user to depress the outer portion toward a first end of the automatic injection device, and an inner ring (32a) coupled to the outer portion. The inner ring is provided proximate to, or in contact with, a bifurcated end (see 788a’ and 788b’) of a plunger. The inner ring has a diameter of between 6.0mm and 6.7mm. When the outer portion is depressed by the user the inner ring engages the bifurcated end of the plunger to disengage the bifurcated end from a firing body (12b) and subsequently trigger dispensing of the dose from the automatic injection device. An automatic injection device and methods for forming a firing button are further disclosed.
Patent NZ-604385-A (NZ)
Title: Glass wine bottles and method of molding them
Inventor: NEMIRE JERALD D
IPC: B65D1/02
Filed: 2011-06-16
Abstract: A glass wine bottle is disclosed that includes a body (22) with a neck (26) coupled to a neck finish (24). The neck finish has either exterior threads (see figure 1), for receiving a screw cap closure, or an exterior shoulder (see 32, figure 3), for coupling by a cork type plug closure press for pressing a cork-type closure. The neck has both external dimensions (L & K) compatible with dimensions of the threaded neck finish and an internal diameter (D) compatible with the cork-type plug neck finish. As such, the neck dimensions facilitate provision of either type of neck finish. Methods of molding, or making, such a glass wine bottle are also disclosed.
Patent NZ-606541-A (NZ)
Title: Anti-cmet antibody
Inventor: WURCH THIERRY
IPC: C07K16/46
Filed: 2009-12-02
Abstract: Disclosed is an isolated monoclonal antibody, or a divalent functional fragment or derivative thereof, capable to inhibit the c-Met dimerization, said antibody comprising a heavy chain comprising CDR-H1, CDR-H2 and CDR-H3 with respectively 5 the amino acid sequences SEQ ID Nos. 1, 2 and 3; and a light chain comprising CDR-L1, CDR-L2 and CDR-L3 with respectively the amino acid sequences SEQ ID Nos. 5, 6 and 7, wherein said antibody comprises a hinge region comprising an amino acid sequence selected from the group consisting of SEQ ID Nos. 59 to 63 and 66 to 70.
Patent NZ-619865-A (NZ)
Title: Folding transom for a collapsible boat
Inventor: KAYE ALEX R
IPC: B63B7/08
Filed: 2012-06-29
Abstract: Collapsible boat with foldable rigid transom includes a collapsible hull formed from a plurality of panels (1, 3, 4) that extend from a first end to a second end of the collapsible. Each of the panels (1, 3, 4) is connected with at least one the other panels (1, 3, 4). The panels including a a port side panel and a starboard side panel each panel having a rear margin disposed to the second end of the boat. The collapsible hull is configurable between a collapsed configuration and an expanded configuration. A folding rigid transom (includes transom member (1, 3, 8) is used to constrain at least two rear margins of the panels (134) when the hull is in the expanded configuration. the hull further comprising a flexible diaphragm connected with the rear margins of the panels, the flexible diaphragm configured to have a substantially compact configuration when the hull is in the collapsed configuration, and the flexible diaphragm providing a water-tight barrier when the hull is in the expanded configuration. The folding rigid transom separate from the flexible diaphragm, and seats remain attached to the at least one of the port side panel or the starboard side panel when the hull is in the collapsed configuration.