baber/WOPTO huggingface dataset:
Patent CA-2870357-A1 (CA)
Inventor: CHIMMANAMADA DINESH U
IPC: C07K7/04
Filed: 2013-04-16
Abstract: Cette invention concerne des composés pharmacologiques comprenant un fragment effecteur conjugué à un fragment de liaison qui dirige le fragment effecteur vers une cible biologique d'intérêt. De la même manière, cette invention concerne des compositions, des kits, et des procédés (par ex., procédés thérapeutiques, diagnostiques, et imagerie) faisant intervenir lesdits composés. Les composés selon l'invention peuvent être décrits comme des composés de type conjugué fragment de liaison interagissant avec une protéine-médicament (SDC-TRAP), qui comprennent un fragment de liaison interagissant avec une protéine et un fragment effecteur. Par exemple, dans certains modes de réalisation concernant le traitement du cancer, le conjugué SDC-TRAP peut comprendre un inhibiteur Hsp90 conjugué à un agent cytotoxique à titre de fragment effecteur.
Patent CA-2875176-A1 (CA)
Title: Producing rigid polyurethane foams
Inventor: FABISIAK ROLAND
IPC: C08G18/76
Filed: 2013-05-29
Abstract: The invention relates to a process for producing rigid polyurethane foams by reaction of A) one or more organic polyisocyanates, B) one or more polyester polyols, C) optionally one or more polyether polyols, D) a flame-retardant mixture, E) further auxiliaries or addition agents, F) one or more blowing agents, and also G) catalysts, wherein said flame-retardant mixture D) comprises d1) 10 to 90 wt%, based on the amount of flame-retardant mixture, of a flame retardant having a boiling point of not more than 220°C, and d2) 10 to 90 wt%, based on the amount of flame-retardant mixture, of a phosphorus-containing flame retardant having a boiling point of above 220°C, wherein said components d1) and d2) total 100 wt%.
Patent CA-2880090-A1 (CA)
Inventor: YERKES CLARA N
IPC: A01N43/78
Filed: 2013-07-19
Abstract: Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): or an agriculturally acceptable salt or ester thereof and (b) a PS II inhibitor, including but not limited to, atrazine, bentazon-sodium, bromoxynil, chlorotoluron, cyanazine, diuron, hexazinone, ioxynil, isoproturon, linuron, methibenzuron, metribuzin, propanil, pyridate, siduron, simazine, simetryne, tebuthiuron and terbuthylazine, or a salt or ester thereof. The compositions and methods provided herein provide control of undesirable vegetation, e.g., in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) or rights of way (ROW).
Patent CA-2880454-A1 (CA)
Title: Improved frame structure for a communication system using adaptive modulation
Inventor: CHEN AN
IPC: H04W72/04
Filed: 2001-11-15
Abstract: A system and method for mapping a combined frequency division duplexing (FDD) Time Division Multiplexing (TDM)/Time Division Multiple Access (TDMA) downlink subframe for use with half-duplex and full-duplex terminals in a communication system. Embodiments of the downlink subframe vary Forward Error Correction (FED) types for a given modulation scheme as well as support the implementation of a smart antennae at a base station in the communication system. Embodiments of the system are also used in a TDD communication system to support the implementation of smart antennae. A scheduling algorithm allows TDM and TDMA portions of a downlink to efficiently co-exist in the same downlink subframe and simultaneously support full and half-duplex terminals. The algorithm further allows the TDM of multiple terminals in a TDMA burst to minimize the number of map entries in a downlink map. The algorithm limits the number of downlink map entries to not exceed 2n +1, where n is the number of DL PHY modes (modulation/FEC combinations) employed by the communication system.
Patent CA-2887499-A1 (CA)
Inventor: RAMSEY WILLIAM
IPC: G06F17/30
Filed: 2013-11-12
Abstract: Various embodiments of the disclosed subject matter include computer-implemented methods, computer-readable media, and computer systems configured to respond to a search query from a computer user. In response to receiving a search query from the computer user, search results are obtained. A plurality of user intents are identified according to the obtained search results. The obtained search results are then grouped according to the subject matter of the search results, where each group corresponds to one of the plurality of user intents. A first user intent (with the corresponding group of search results) is selected. A search results page is generated from the search results of the group the search results corresponding to the selected first user intent and the generated search results page is returned to the computer user in response to the search query.
Patent CA-2887697-A1 (CA)
Inventor: CHANG BETTY Y
IPC: A61K31/506
Filed: 2013-10-11
Abstract: The invention provides methods, assays and systems for determining the efficacy of a TEC family kinase inhibitor on a target kinase. The methods, assays and systems relate to determining the occupancy of a target kinase by a TEC family kinase inhibitor (e.g., BTK inhibitors). Such quantitative measurements are used to inform therapeutic treatment and the over-all health care management of a subject. For example, diagnostic kits for diagnosing, prognosing, and monitoring a disease or indication benefitting from treatment with a TEC family kinase inhibitor are provided. In another example, diagnostic kits for identifying responders to TEC family kinase inhibitor therapy, determining therapeutic regimens, and detecting resistance to TEC family kinase inhibitor also are provided.
Patent CA-2889871-A1 (CA)
Title: Motor-driven fastening tool
Inventor: FLEISCHER ERIC C
IPC: B25C5/00
Filed: 2015-04-29
Abstract: A fastening tool is provided with a housing having a fastener outlet. A striker is mounted for translation in the housing to drive a fastener from the fastener outlet in an unloaded position. A biasing member cooperates with the striker to urge the striker towards the unloaded position. A motor is oriented in the housing. A cam is driven by the motor, and has a cam surface in cooperation with the striker such that rotation of the cam translates the striker to a loaded position and to a release position whereby the biasing member drives the striker to the unloaded position. The cam surface is profiled to require a constant torque from the rotary input during translation of the striker to the loaded position while loading the, biasing member.
Patent CA-2891286-A1 (CA)
Inventor: VAN DE VEERDONK WILCO JOHANNES ADRIANUS ANTHONIUS
IPC: B65G1/137
Filed: 2013-11-13
Abstract: The invention relates to a method for collecting a number of different products listed in an order in a product collecting system, comprising the following steps: allocating a product listed in an order to the order if said product is already available in the module (S7), allocating a product to the order (S7) if said product of the "slow-moving" type is not already available in the module whereas it is available in another module (S5), and moving said product from said other module to the module (S6), and unloading a product carrier carrying a product at least in part (S8) if such a type of product is not already available in the module nor in another module, in which case the product is allocated to the order (S7) and moved to the module, and releasing the order and loading the products onto a collecting carrier (S9) when all the products listed in the order have been collected in the module (S2).
Patent CA-2895578-A1 (CA)
Inventor: KULAK NILS A
IPC: B01D15/22
Filed: 2013-12-19
Abstract: The present invention relates to sample preparation container for purification and/or enrichment of bio-organic compounds from cellular material, viruses and/or sub-components of said cellular material and/or viruses, the container comprising a reaction chamber and a chromatography medium; wherein said reaction chamber is for holding said cellular material, viruses and/or sub-components of said cellular material and/or viruses and is configured such that at least one of the following reactions can be performed therein: lyis, e.g. by sonication and/or boiling; chromatographic purification; reduction; alkylation; and enzymatic reactions such as proteolysis; wherein said chromatography medium is configured to purify and/or enrich said bio-organic compounds; wherein (a) said chromatography medium is located at a wall of said reaction chamber, and said wall is closed or sealed and configured to be opened for obtaining purified and/or enriched bio-organic compounds; or (b) said sample preparation container further comprises a receiving chamber for receiving said bio-organic compounds, said receiving chamber being adjacent to said chromatography medium such that said chromatography medium separates said reaction chamber from said receiving chamber, and the outer face of said receiving chamber is closed and configured to be opened for obtaining purified and/or enriched bio-organic compounds.
Patent CA-2896385-A1 (CA)
Inventor: BARMSCHEIDT CHRISTIAN
IPC: E05B77/02
Filed: 2013-11-22
Abstract: The object of the present invention is a motor vehicle door lock, comprising a locking mechanism and an electrical drive (4, 5) for electrically opening the locking mechanism. According to the invention, a complementary drive (7, 8) is provided in addition to the electrical drive (4, 5) for electrically opening the locking mechanism. With the aid of the electrical drive (4, 5), the additional drive (7, 8) releases, for the purpose of electrically opening the locking mechanism, a mechanical safety mechanism of the respective electrical drive (4, 5), which is formed by a blocking element (2).
Patent CA-2900015-A1 (CA)
Inventor: LABBE CHRISTIAN
IPC: B62K21/16
Filed: 2013-06-12
Abstract: An adjustable handlebar riser assembly has an outer member, an inner member, a pin, a retainer member and a locking member. The inner member and the outer member have mating flat-bottom V-shaped faces. The inner member slides at least in part within the outer member. Each of the outer and inner members has at least one aperture through their flat-bottom V-shaped faces. The pin is inserted in an aperture of the outer member and in an aperture of the inner member. The retaining member is connected to the pin at one end while the locking member is connected to an opposed end of the pin. The locking member can exert a tension on the pin, pressing the outer member onto the inner member for locking these members at a selected position relative to one another.
Patent CA-2901300-A1 (CA)
Inventor: KEYSER STEPHEN RICHARD
IPC: A61M25/06
Filed: 2009-01-09
Abstract: This invention provides devices and methods for insertion of a catheter into a vessel. The devices include coaxial slidably mounted needle, dilator and catheter components. The methods include piercing a vessel with the needle component, dilating the pierced hole with the dilator component, retraction of the needle component, insertion of the catheter and withdrawal of the dilator.
Patent CA-2903802-A1 (CA)
Inventor: HAMSTRA STEPHEN A
IPC: F24F11/02
Filed: 2014-03-04
Abstract: La présente invention se rapporte à un procédé permettant de concevoir un système de chauffage et de refroidissement optimisé, ledit procédé consistant à : (1) simuler une utilisation de l'énergie d'un système de chauffage et de refroidissement virtuel qui fait fonctionner une première source thermique potentielle ou un premier dissipateur thermique dans une pluralité de conditions ; (2) simuler une utilisation de l'énergie du système de chauffage et de refroidissement virtuel faisant fonctionner une seconde source thermique potentielle ou un second dissipateur thermique dans une pluralité de conditions ; (3) optimiser l'utilisation de l'énergie du système virtuel faisant fonctionner la première source thermique potentielle ou le premier dissipateur thermique ou la seconde source thermique potentielle ou le second dissipateur thermique à l'aide d'une optimisation de réseau neuronal ; et (4) concevoir un système de chauffage et de refroidissement sur la base de l'optimisation de l'utilisation de l'énergie du système virtuel.
Patent CA-2904671-A1 (CA)
Title: Traitement d'un dysfonctionnement cardiaque diastolique avec un agoniste de recepteur trpv2
Inventor: RUBINSTEIN JACK
IPC: A61K33/22
Filed: 2014-03-13
Abstract: La présente invention concerne des procédés de traitement d'un dysfonctionnement cardiaque diastolique et des symptômes de celui-ci chez un sujet, qui comprennent l'administration d'une quantité d'un agoniste de récepteur TRPV2 efficace pour traiter le dysfonctionnement cardiaque diastolique. L'agoniste de récepteur TRPV2 peut être administré par au moins un mode parmi une injection, la voie orale, ou la voie transdermique. La quantité d'agoniste de récepteur TRPV2 est suffisante pour conduire à un fonctionnement amélioré sur la base de critères diagnostiques quantitatifs. Dans un mode de réalisation, l'agoniste de récepteur TRPV2 est administré sur une période d'environ 8 heures à environ 24 heures. L'agoniste de récepteur TRPV2 peut être utilisé pour des traitements à court terme, c'est-à-dire, moins d'une semaine, ou il peut être administré à long terme, c'est-à-dire, sur une période de plusieurs semaines, mois, ou même années. Des agonistes de récepteur TRPV2 exemplaires comprennent le probénécid, le borate de 2-aminoéthoxydiphényle, le cannabinol, le cannabidiol, et des combinaisons de ceux-ci.
Patent CA-2905259-A1 (CA)
Inventor: STEEN MARK
IPC: A61F9/007
Filed: 2014-02-26
Abstract: The present invention relates generally to providing pressurized infusion of liquids and, more particularly, is directed to providing a stable and pressurized flow of irrigation fluid to the eye during surgery.
Patent CA-2907793-A1 (CA)
Title: Lattice mast element
Inventor: ZIMMER WALTER
IPC: B66C23/70
Filed: 2014-03-18
Abstract: A lattice-mast element (15) for a crane comprises at least two longitudinal elements (21) and at least one transverse element (22), which connects the longitudinal elements (21) to one another, and at least one reinforcing element (24) for reinforcing the lattice-mast element (14; 15; 16; 54; 56; 57; 58) by connecting the longitudinal elements (21) and/or the transverse element (22) to one another, wherein the longitudinal elements (21) and the transverse element (22) bound a bearing-load surface of the lattice-mast element (15) and the longitudinal elements (21) are each configured in the form of a two-dimensional load-bearing structure.
Patent CA-2909208-A1 (CA)
Inventor: PRAKASH SATYA
IPC: A61K38/18
Filed: 2014-04-11
Abstract: The present disclosure provides viral microparticles comprising genetically-engineered baculoviruses (at least partially) embedded in a polymeric matrix for the local delivery of therapeutic nucleic acid molecules to the cells of a vertebrate individual (optionally in combination with a medical implant such as vascular stent platform). The viral microparticles are especially useful for promoting the healing of a wound as well as the repair of a blood vessel and prevent pathological scarring. Also provided herein are processes for making the viral microparticles, pharmaceutical compositions comprising viral microparticles as well as supports comprising the viral microparticles for the locating the viral microparticles in a wound or in the vicinity of a wound.
Patent CA-2911340-A1 (CA)
Title: Sand worm lyophilisate and uses thereof
Inventor: ZAL FRANCK
IPC: A23J1/04
Filed: 2014-05-14
Abstract: The invention relates to a lyophilisate or to a powder including i) at least one globin, a globin protomer or an extracellular hemoglobin from annelids, and ii) at least one biological material from annelids that is different from said globin, from said protomer, and from said hemoglobin.
Patent CA-2915758-A1 (CA)
Inventor: DANIELSSON ANDERS
IPC: B65D41/34
Filed: 2014-06-16
Abstract: A cap arranged to interact with a spout has a top portion, a sidewall portion (104) depending from the top portion and formed in one piece therewith. The sidewall portion (104) has an interior threading arranged to interact with exterior threading of the neck during an opening operation and during a closing operation. The cap further has cutting elements (112) with a first end hingedly attached to the sidewall portion and a free end portion arranged to interact with a membrane portion of the spout. The hinged attachment allows for the cutting element to pivot in an axial direction. Further, the free end portion has a blunt tip (112B) and a comparatively sharper cutting edge (112A) on a lateral side of the free end portion for cutting the membrane portion when unscrewing the cap.
Patent CA-2916659-A1 (CA)
Title: Biochemical energy conversion cell
Inventor: STEIN EMILY A
IPC: H01G9/20
Filed: 2014-06-25
Abstract: Presented herein is a voltaic cell containing light harvesting antennae or other biologically-based electron generating structures optionally in a microbial population, an electron siphon population having electron conductive properties with individual siphons configured to accept electrons from the light harvesting antennae and transport the electrons to a current collector, an optional light directing system (e.g., a mirror), and a regulator having sensing and regulatory feedback properties for the conversion of photobiochemical energy and biochemical energy to electricity. Also presented herein is a voltaic cell having electricity-generating abilities in the absence of light. Also presented herein is the use of the voltaic cell in a solar panel.
Patent CA-2917569-A1 (CA)
Inventor: CRARY JOHN
IPC: A61P25/00
Filed: 2014-07-11
Abstract: This invention relates to the treatment and prevention of Alzheimer's disease (AD), tangle-predominant dementia (TPD) and other diseases associated with abnormal tau expression, e.g., tauopathies, using the 3 'untranslated region (UTR) of the tau messenger RNA (mRNA) as a target, specifically using microRNAs that regulate the expression of tau. This invention is also in the field of screening for, identifying, and diagnosing such diseases. Specifically, this invention provides biomarkers for these diseases in the form of microRNAs.
Patent CA-2921064-A1 (CA)
Inventor: SIEBERT MAX
IPC: C23C14/04
Filed: 2014-04-24
Abstract: The invention relates to a holder for securing at least one rod-shaped substrate body (10) having a variable cross-section along the substrate body and having a substrate body region BQ1 comprising a surface to be treated. The holder comprises at least one perforated wall as the front wall (3), said wall having at least one opening (5), and also comprises a support element (9) and a retaining element (11). The support element (9) is constructed and/or secured in the opening (5) in such a way that at least part of the substrate body can be arranged longitudinally and obliquely in the support element (9) and the retaining element (11) is constructed and/or secured in the opening (5) in such a way that said retaining element (11) can retain the substrate body at a point between the region BQ1 and the remainder of the substrate body such that the region BQ1 protrudes from the holder through the opening (5).
Patent CA-2926274-A1 (CA)
Inventor: ZAZULA RENNIE K
IPC: E21B21/06
Filed: 2016-04-07
Abstract: A system and method for recovering drilling fluid from shaker tailings includes a hopper and a cover that is pivotable between a first position in which the hopper is uncovered and a second position in which the hopper is covered. In the first position, the hopper receives the tailings, which are pumped via a low shear pump to a centrifuge. The drilling fluid extracted in the centrifuge is stored in a holding tank. In the second position, the cover is angled with respect to the direction of gravity so as to divert shaker tailings from being received in the hopper. Some fluid from the holding tank is sprayed into the hopper through nozzles to convey the deposited tailings toward the pump. A level detector senses the level of the mixture in the hopper, and an associated control system controls the pump speed and the cover position to control the operation.
Patent CA-2926332-A1 (CA)
Title: Ubiquitinylated proteins
Inventor: TWITTY CHRISTOPHER
IPC: A61P37/02
Filed: 2014-10-10
Abstract: A method of inducing a specific immune response in a mammal, comprising: providing a first composition comprising isolated ubiquitinylated proteins in solution in the absence of membrane bound organelles, the isolated ubiquitinylated proteins comprising one or more specific antigens, and further comprising a threshold quantity of polyubiquitinylated short-lived proteins and polyubiquitinylated defective ribosomal products. The isolated ubiquitinylated proteins are affinity-purified from tumor-derived cells grown in culture, the tumor-derived cells being inhibited from degrading ubiquitinylated proteins via the proteasome while being grown in culture. In this way, highly immunogenic short-lived proteins and defective ribosomal products may be loaded onto dendritic cells for cross-presentation and priming of antigen-specific T cells restricted by either classical or non-classical MHC.
Patent CA-2928890-A1 (CA)
Inventor: DOHRING DIETER
IPC: B32B27/42
Filed: 2014-01-14
Abstract: The present invention concerns a layered building board for inside and outside, comprising a core layer (20) and a melamine-impregnated paper (21) arranged thereon. In order to improve the adhesion of further layers, an adhesion layer (30) comprising polyurethane and acrylate is provided on the paper.
Patent CA-2932188-A1 (CA)
Title: Centrifugeur decanteur et methodes d'utilisation associees servant a deshydrater des residus fins (fluides) matures
Inventor: MAXWELL THOMAS J
IPC: B04B7/08
Filed: 2016-06-07
Abstract: Il est décrit une centrifugeuse décanteuse qui comporte un bol; un transporteur à vis; un tube ascendant; une chambre pour les matières premières; un accélérateur dans la chambre pour les matières premières; et une buse de redirection des matières premières; le transporteur à vis comporte un corps de transporteur et une vis sans fin, le transporteur à vis définissant un passage axial entre le corps de transporteur et un bord orienté de manière radiale vers lintérieur de la vis sans fin; la centrifugeuse décanteuse est structurée de telle sorte que, lors de son utilisation, un mélange de matières premières passe à travers le tube ascendant et dans la zone des matières premières où la vitesse angulaire du mélange de matières premières est augmentée par laccélérateur, le mélange de matières premières sort ensuite de la zone des matières premières, est redirigé par la buse de redirection des matières premières dans une direction axiale vers une chambre de sédimentation à lintérieur du bol et à travers le passage axial, et la rotation du transporteur et du bol provoque une sédimentation à lintérieur du bol, pour séparer les solides et les liquides dans le mélange de matières premières.
Patent CA-2934368-A1 (CA)
Title: Helmet for impact protection
Inventor: LAPERRIERE JEAN-FRANCOIS
IPC: A42B3/06
Filed: 2014-12-19
Abstract: A helmet for protecting a head of a wearer, such as a hockey, lacrosse, football or other sports player. The helmet comprising an outer shell and an inner padding disposed between the outer shell and the wearer's head when the helmet is worn. The inner padding comprising a plurality of shock absorbers and an interconnector interconnecting the shock absorbers, each shock absorber being deformable in response to a rotational impact on the helmet such that an outer part of the shock absorber moves relative to an inner part of the shock absorber in a direction tangential to an angular movement of the outer shell due to the rotational impact.