Patent SG-11201901177V-A (SG)
Title: Sustained local delivery of drugs including antibiotics
Inventor: CHAPANIAN RAFI
IPC: A61P31/00
Filed: 2017-08-17
Abstract: Oc d 1 ------- d2 114c 114b (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 22 February 2018 (22.02.2018) WIP0 I PCT (10) International Publication Number WO 2018/035356 Al O II (51) International Patent Classification: A61K 9/70 (2006.01) A61K 47/26 (2006.01) A61L 31/04 (2006.01) A61K 47/34 (2017.01) A61L 31/10 (2006.01) A61K 31/4164 (2006.01) A61L 31/14 (2006.01) A61K 31/545 (2006.01) A61L 31/16 (2006.01) A61P 31/00 (2006.01) A61K 47/10 (2017.01) (21) International Application Number: PCT/US2017/047410 (22) International Filing Date: 17 August 2017 (17.08.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/376,204 17 August 2016 (17.08.2016) US (71) Applicant: EUPRAXIA PHARMACEUTICALS INC. [CA/CA]; 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). (72) Inventors: CHAPANIAN, Rail; c/o Eupraxia Pharmaceu- ticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). HELLIWELL, James, A.; c/o Eupraxia Pharmaceuticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). MALONE, Amanda; c/o Eupraxia Pharmaceuticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Co- lumbia V8R 5J2 (CA). PECK, Vik; c/o Eupraxia Pharma- ceuticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). LOSS, Troy; c/o Euprax- ia Pharmaceuticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). GOUDARZI, Azadeh; c/o Eupraxia Pharmaceuticals Inc., 2590 Cadboro Bay Road, Unit 204, Victoria, British Columbia V8R 5J2 (CA). (74) Agent: HAN, Hai et al.; Seed Intellectual Property Law Group LLP, Suite 5400, 701 Fifth Avenue, Seattle, Wash- ington 98104-7064 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (54) Title: SUSTAINED LOCAL DELIVERY OF DRUGS INCLUDING ANTIBIOTICS 114 132 134 144 142 Ha 113 0 (57) : Described herein are extended release composite film comprising a drug-loaded membrane coated with porous coatings \" that is capable of localized release of drug (e.g., antibiotics) for surgical prophylaxis. [Continued on next page] 100 120 110 140 WO 2018/035356 Al MIDEDIMOMOIDEIREIHNIOMEMMOMEEM TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3))