baber/WOPTO huggingface dataset:
Patent HR-P20120341-T1 (HR)
Title: Pharmaceutical formulations of hdac inhibitors
Inventor: RICHARD J BASTIN
IPC: A61P35/00
Filed: 2012-04-17
Abstract: This invention pertains to pharmaceutical compositions comprising certain carbamic acid compounds (e.g., which inhibit HDAC (histone deacetylase) activity) (e.g., PXD-101, N-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide)) and one or more additional ingredients selected from cyclodextrin, arginine, and meglumine. The present invention also pertains to the use of such compositions, for example, in the inhibition of HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc.
Patent SI-1343387-T1 (SI)
Title: DECONTAMINATION OF ANIMAL FEED CONTAINING PRION (eg. BSE agent).
Inventor: KEMP PHILIP WILLIAM
IPC: A23K1/10
Filed: 2001-11-14
Abstract: A method of producing an animal feed that is free from transmittable degenerativeencephalopathies is provided. Central to the method is alkali treatment of animalmaterial at a pH of at least 8.5 under temperature conditions below 100 C at atmospheric pressure. This method provides a decontaminated animal feed produced under relatively low temperature and pressure conditions that are achievable instandard animal carcass rendering facilities.
Patent SI-1576967-T1 (SI)
Title: Recombinant protein, carrying human papillomavirus epitopes inserted in an adenylate cyclase protein or fragment thereof, therapeutic uses thereof
Inventor: PREVILLE XAVIER-EDMOND-EDOUARD
IPC: C07K14/235
Filed: 2004-03-18
Abstract: The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several HPV antigens, said polypeptides being inserted in the same or different permissive sites of an adenylate cyclase (CyaA) protein or of a fragment thereof, wherein said CyaA fragment retains the property of said adenylate cyclase protein to target Antigen Presenting Cells.It also concerns polynucleotides encoding the same. The recombinant protein or the polynucleotide can be used for the design of therapeutic means against HPV infection or against its malignant effects.
Patent SI-1651260-T1 (SI)
Title: Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof
Inventor: ROOF MICHAEL B
IPC: A61K39/00
Filed: 2004-07-15
Abstract: The present invention relates to Lawsonia intracellularis vaccines and methods for protecting against and diagnosing L. intracellularis infection. The products and processes of the invention are attainable, in part, as the result of an improved method for cultivating large scale supplies of L. intracellularis, including both a novel isolate of L. intracellularis of European origin and a method of preparing a lyophilized product containing the attenuated European isolate as vaccine product.
Patent SI-1718337-T1 (SI)
Title: New combinations of a 5-ht3 receptor antagonist with racecadotril or dexecadotril
Inventor: SCHWARTZ JEAN-CHARLES
IPC: A61P1/00
Filed: 2005-02-14
Abstract: The present invention concerns new combinations of an anti-emetic agent and an enkephalinase inhibitor, the uses of said combinations for treating diarrhea and/or gastroenteritis.
Patent SI-2142174-T1 (SI)
Title: Stable aqueous g-csf formulations
Inventor: FURTINGER SABINE
IPC: A61K9/08
Filed: 2008-04-04
Abstract: The invention relates to stable glutamate-buffered G-CSF formulations having a pH of from 3.5 to 4.8. The invention further concerns lyophilisates and powders obtainable from such formulations, and to pharmaceutical kits containing such lyophilisates and powders.
Patent SI-2188155-T1 (SI)
Title: Device for fastening plastic parts to a motor vehicle body
Inventor: SCHRAER THORSTEN
IPC: F16B5/00
Filed: 2008-07-24
Abstract: The invention relates to a device for fastening plastic parts (10) to a motor vehicle body (12), having an internal thread (14) which is formed on the body (12) and having a screw (16) which has an external thread (18) and which is provided with an oversized head (20), which screw (16) is inserted into the internal thread (14), wherein a cylindrical sleeve (22) is placed between the screw head (20) and the body (12), the inner diameter of which cylindrical sleeve (22) is significantly larger than the outer diameter of the external thread (18) of the screw (16), and wherein a cylindrical sleeve (24) is attached coaxially, by means of its inner edge which faces toward the body (12), to the outer edge, which faces away from the body (12), of the sleeve (22), the inner diameter of which cylindrical sleeve (24) forms a fit with the outer diameter of the sleeve (22), and which cylindrical sleeve (24) ends, at its body-side end, in an outwardly extending disk (26), the outer diameter of which corresponds approximately to the outer diameter of the screw head (20), wherein an opening (28) for receiving the device is provided in the plastic part (10), the inner diameter of which opening (28) is larger than the outer diameter of the sleeve (24) but smaller than the outer diameter of the flat washer or of the oversized screw head (20) and of the disk (26) which is attached to the sleeve (24).
Patent SI-2573119-T1 (SI)
Title: Antibodies that bind IL-4 and/or IL-13 and their uses
Inventor: RAO ERCOLE
IPC: C07K16/00
Filed: 2008-10-14
Abstract: The present invention relates to a polyvalent bispecific antibody format which comprises a first polypeptide which is a constant heavy chain and a second polypeptide which is a constant light chain, wherein the first polypeptide is attached to two or more variable domains of a heavy chain and the second polypeptide is attached to two or more variable domains of a light chain. A preferred embodiment of the present invention refers to a tetravalent bispecific tandem immunoglobulin (TBTI). 
The polyvalent bispecific antibodies of the present invention resemble and keep the stability characteristics of an immunoglobulin molecule, expressing the heavy and light chains on two different polypeptides and incorporating the constant heavy regions and the constant light regions in order to stabilize the interaction between the variable heavy and the variable light domains and to force correct pairing of the corresponding VHNL. The present invention further refers to the uses of such polyvalent bispecific antibodies.
Patent TR-200001694-T1 (TR)
Inventor: HEINDORF HELMUT
IPC: H01R13/639
Filed: 1999-08-11
Abstract: The invention relates to a connecting device for two components, especially individual electrotechnical components (13,14) such as power circuit breakers, residual-current circuit breakers or similar. The inventive connection device consists of a connecting clip (1) which is simultaneously inserted into a receiving fixture for said connection clip (1) in two components (A,B) that are to be connected. The connection clip is anchor-shaped and basically consists of a rod (2) and an anchor bar (4) extending perpendicularly thereto. The free end of the rod (2) is configured as a snap-in element (5). The ends of both sides of the anchor bar (3) are bent and form insert sections (25). The receiving fixture for the connection clip consists of both a groove (20) which is provided on one side of a component that is to be connected, whereby said groove is open on one side, and an insert receiving fixture (25) that extends close to the groove (20) inside the component that is to be connected. When two components that are fitted with said receiving fixture for a connection clip are connected, they are placed adjacent to each other in such a way that both grooves (20) form an opening, whereby the rod (2) of the connection clip and the snap-in element thereof are introduced into said opening. The insert sections (4) simultaneously engage with the insert receiving fixtures (25). The snap-in elements (5) on the connection clip (1) engage with (5) an undercut (24) provided in the groove (20), whereby the connection becomes non-detachable.
Patent TR-200200516-T1 (TR)
Title: Ergimiş haldeki katkı maddelerinin duhul edilmesine yönelik göbekli tel
Inventor: RICHE DOMINIQE
IPC: C21C1/10
Filed: 2001-06-27
Abstract: Bu bulus ergimis haldeki bir metal banyosuna katki maddelerinin duhul edilmesine yönelik katki maddesi göbekli bir tel ile ilgili olup, bir katki maddesi (6) ihtiva eden bir metal kilif (5) içerir, ve metal kilif da bir muhafaza (7) ile örtülür ve muhafaza da yanma kabiliyetine sahiptir, fakat arzu edilmeyen bakiyeler olusturmaz, ve katki maddesi göbekli tel göbege sicakligin yayilmasini bir an için önler. Sözü geçen katki maddesi göbekli tel yukarida sözü geçen muhafazanin üzerinde, metalik bir koruyucu tabakanin katki maddesi, metal kilif ve yanabilen muhafazanin meydana getirdigi asamblaji sarmasi/örtmesi ile tanimlanir.
Patent DE-3650669-T2 (DE)
Inventor: KRAUSE JAMES N
IPC: G11B5/55
Filed: 1986-11-19
Granted: 1998-07-23
Abstract: A thermal test track (- 3) is provided outside the user-accessible area on the disc. A track complete of a known frequency is then written on either side of this thermal test track, preferably half the usual track separate distance away. To develop a thermal compensation constant, the transducer (10) is moved to the thermal test track with no compensation applied. This way, any thermally induced off-track error, which would affect seeks to user-accessible data tracks, will be reflected in the off-track from the nominal position of the thermal test track. The transducer is now moved in a series of defined increments (e.g. 5) smaller than normal track-to-track steps, or "micro-steps", away from the uncompensated position of the thermal track toward one of the tracks written with the known frequency. When the data on the written track to the side of the thermal test track is detected, a note is made of the number of micro-steps the transducer has been moved. The transducer (10) is then micro-stepped incrementally in the opposite direction until the data written on the other side of the thermal test track is detected. A simple comparison of these two micro-step counts will yield the existing thermal shift, which can be converted into a thermal compensation constant for the transducer positioning mechanism by means of a simple look-up table.
Patent DE-3783014-T2 (DE)
Inventor: HERBSLEB PEER
IPC: H05B47/11
Filed: 1987-10-29
Granted: 1993-06-03
Abstract: A device for producing alternating electric current of high frequency for power consumers such as fluorescent tubes (Ly1, Ly2) comprises a transformer with a winding (n3) connected in series with an output terminal (e) and active electronic components such as transistors (T1, T2) controlling the output current, the transistors being controlled by electric voltages produced by inductive feedback in feedback windings (n11, n12). Magnetic saturation is utilized to modify the inductive relationship in such a way that the transistors (T1, T2) cyclically change the direction of the output current. The feedback takes place in two magnetic cores (Tr1, Tr2) of the transformer, each core being provided with at least one further electric magnetization winding designated a command winding (n5, n6) as electric current is fed through the command windings to control magnetic saturation of the magnetic cores (Tr1, Tr2). As a result, combined control of the frequency and of the active electric power in the fluorescent tubes (Ly1, Ly2) is possible so that the luminous power may be controlled over a wide range while suitably high voltages can be maintained to ignite the tubes properly.
Patent DE-3851696-T2 (DE)
Inventor: BROCKWAY WILLIAM J
IPC: C07K14/755
Filed: 1988-12-13
Granted: 1995-02-23
Abstract: Highly purified antihemophilic factor is produced by a process comprising a PEG precipitation step, a gel filtration step and a virus inactivation step. Al(OH)3 adsorption and PEG precipitation carried out at room temperature allow processing to proceed directly to a gel filtration step.
Patent DE-3855220-T2 (DE)
Inventor: JUDY MILLARD
IPC: A61L2/10
Filed: 1988-06-24
Granted: 1996-11-14
Abstract: A method for externally eradicating infectious pathogenic contaminants, such as enveloped viruses, bacteria, trypanosomal and malarial parasites, present in body tissues, such as blood, blood components, semen, skin, and cornea, before the treated body tissues are introduced into, or transplanted onto, the body of a human or an animal. Such method includes the steps of: (1) admixing an effective, non-toxic amount of photoactive compound, which has a selectively for binding to the infectious pathogenic biological contaminants present therein, with the body tissues outside the body to produce resulting body tissues; (2) maintaining the resulting body tissues in a suitable container in which there is no net mass transfer, and (3) irradiating the resulting body tissues in the container for an effective period of time with an effective level of radiation such that the radiation penetrates the resulting body tissues and eradicates the photoactive-compound-bound contaminants present in the resulting body tissues and produces a decontaminated body tissue suitable for introducing into, or transplanting onto, the body of a human or animal.
Patent DE-3856298-T2 (DE)
Inventor: KACIAN DANIEL LOUIS
IPC: C12Q1/04
Filed: 1988-03-31
Granted: 1999-06-02
Abstract: A method of assaying a biological specimen, such as a mucoid secretion specimen, for the presence of selected bacterial species, such as mycobacteria, wherein the selected bacterial species are concentrated from the biological specimen into a concentrated specimen by concentrating white blood cells from said biological specimen, which white blood cells are associated with a portion of said selected bacterial species.
Patent DE-3877286-T2 (DE)
Inventor: DAIGRE JEAN CLAUDE
IPC: A47B49/00
Filed: 1988-08-05
Granted: 1993-07-22
Abstract: This item of filing furniture comprises a base which supports a vertical column on which is mounted at least one revolving filing drum (3), whose cross section is a quadrilateral in which four filing compartments (4) are made, the respective positions of which are deducible from one another by rotation through 90 DEG  about the column and whose openings are located, respectively, on the four front faces of the drum (3). The drum (3) consists of a vertical central sleeve (6) mounted in rotation on the column from which radiate four uniformly spaced vertical walls (7) arranged in pairs symmetrically relative to the axis of the drum, each having two rectangular vertical wings (7A), (7B), separated by a vertical folding line, the first (7A) of which is fixed to the central sleeve (6) and extends parallel to one of the median lines of the quadrilateral and the second (7B) of which extends along the side of the quadrilateral intersecting this median line and forms the solid part of the corresponding front face. <IMAGE>
Patent DE-3877767-T2 (DE)
Inventor: RULE MARK
IPC: C08G75/02
Filed: 1988-10-18
Granted: 1993-08-05
Abstract: A copoly(arylene sulfide) corresponding to the structure  [ (-A-S-)1-x(-A-S-S-)x] n wherein x is in the range of 0.5 to 0.001 and a process for its preparation by reacting a mixture of a diiodoaromatic compound and elemental sulfur.
Patent DE-3884416-T2 (DE)
Inventor: KIMURA SHUICHI C O PATENT DIVI
IPC: G11B21/08
Filed: 1988-02-01
Granted: 1994-02-03
Abstract: An access control apparatus for use with a disc drive having a head (2) movable with respect to tracks (TR) on a disc (1) to produce a reproduced signal (RF) containing a data signal. The access control apparatus includes a drive device (4) for moving the head (2) in a direction (6) radially of the disc (1) to perform rapid access from one track to a desired track. A traverse detector (11) is provided for producing traverse detection pulses (SH) in response to the data signal. The traverse detector (11) includes a trigger signal generator (21) responsive to the data signal for producing trigger pulses (STH) for respective cycles of the data signal having a magnitude greater than a predetermined value, and a timer (22) responsive to each of the trigger pulses for changing to a first state. The timer returns to a second state a predetermined time after each trigger pulse occurs. A counter (6) counts the traverse detection pulses (SH) to accumulate a count corresponding to the number of tracks traversed by the head (2). The drive device (4) is controlled in accordance with the count in the counter (6). A second traverse detector (12) may also be provided for low speed traversing, an access speed detector (26) activating a switch (13) to select one of the traverse detectors (11, 12) depending upon the access speed of the head (2).
Patent DE-60000734-T2 (DE)
Inventor: HEMATI MEHRDJI
IPC: B01J2/16
Filed: 2000-04-05
Granted: 2003-08-21
Abstract: The invention concerns a method for coating and film-coating fine powders, characterised in that it consists in adding to the fine particles a sufficient amount of large-sized particles (about 0.4 to 1 mm in size) in a proportion of 30 %.
Patent DE-60003695-T2 (DE)
Inventor: HASZLER JOHANN
IPC: G01B15/02
Filed: 2000-08-10
Granted: 2004-06-03
Abstract: The invention refers to a device for measurement of the thickness of a first layer, comprising one or more sublayers, on a second layer of a metal sheet by X-ray fluorescence analysis comprising means for generating and directing a beam of polychromatic primary X-rays, said beam being able to penetrate into the first and second layers for converting primary X-rays into chemical element specific fluorescent X-rays by means of absorption of primary X-rays and re-emission of fluorescent X-rays by the chemical element, and further comprising means for detecting element specific fluorescent X-rays and determining an intensity thereof. The means for detection have been placed at an angle with respect to the primary beam of X-rays in dependence of the chemical element from which the fluorescent X-rays are to be detected. Herewith an improvement of the efficiency of detection is achieved, and the measurement time is reduced accordingly. Hence, a device is provided with which alloys with a low concentration of fluorescent elements can now be analysed, for determining the thickness of a cladding.  <IMAGE>
Patent DE-60004511-T2 (DE)
Inventor: MUNRO SEMPLE
IPC: D06N7/00
Filed: 2000-04-13
Granted: 2004-06-17
Abstract: A process for coating a perforated substrate with a gel (e.g. a polymerised acrylate hydrogel or a xerogel) without substantial occlusion of the perforations comprises (i) forming a layer of a liquid pregel mixture, comprising one or more monomers, on a web coated with a silicone, polyethylene, Teflon(R) or other coating having a surface energy less than the surface energy of the liquid pregel mixture. Preferably at least part of the curing takes place while the liquid pregel mixture is in contact with both the perforated substrate and the web. The process is especially applicable to the manufacture of attachment tabs for wigs and toupees, wound dressings, patches for transdermal drug delivery, therapeutic patches or biomedical electrodes.
Patent DE-60010860-T2 (DE)
Inventor: BUXTON CHRISTOPHER
IPC: B04B5/04
Filed: 2000-02-08
Granted: 2005-05-25
Abstract: A centrifuge rotor including a sample carrier (1) enclosing within an outer housing (7,8) and being rotatable about a principal axis of rotation of the rotor, the sample carrier (1) having a peripheral zone for holding sample tubes (6) in an orientation parallel to the said axis when at rest and the sample carrier being capable of deflecting to enable sample tubes (6) to swing out under the effect of centrifugal force. The swinging out of the tubes (6) is constrained and controlled by the arrangement of the sample carrier (1) and contact between the tubes (6) and outer housing (7,8).
Patent DE-60015314-T2 (DE)
Inventor: CARLSSON BO
IPC: F02B25/22
Filed: 2000-01-14
Granted: 2005-11-10
Abstract: Crankcase scavenged two-stroke internal combustion engine (1) in which a piston ported air passage is arranged between an air inlet (2) and the upper part of a number of transfer ducts (3, 3'). The air passage is arranged from an air inlet (2) equipped with a restriction valve (4), controlled by at least one engine parameter, for instance the carburettor throttle control. The air inlet extends via at least one connecting duct (6, 6') to at least one connecting port (8, 8') in the engine's cylinder wall (12). The connecting port (8, 8') is arranged so that it in connection with piston positions at the top dead centre is connected with flow paths (10, 10') embodied in the piston (13), which extend to the upper part of a number of transfer ducts (3, 3'). Each flow path through the cylinder and piston is to a great extent arranged in the cylinder's lateral direction, on the one hand in that the connecting port (8, 8') and adjacent scavenging port (31, 31') of the cylinder are shifted sideways in relation to each other along the periphery of the cylinder wall (12), and on the other hand in that the transfer ducts (3, 3') of the cylinder are running essentially in the cylinder's lateral direction away from each transfer port (31, 31') respectively, i.e. tangentially in relation to the circumference of the cylinder wall (12).
Patent DE-60019394-T2 (DE)
Inventor: KIM JAE-YOEL
IPC: H04B1/707
Filed: 2000-07-07
Granted: 2005-09-08
Abstract: A scrambling code generating apparatus of a downlink transmitter in a UMTS mobile communication system, which uses one primary scrambling code for separation of base stations and multiple secondary scrambling codes for channel separation. The apparatus includes a first m-sequence generator for generating a first m-sequence and a second m-sequence generator for generating a second m-sequence. A first summer adds the first and second m-sequences to generate the primary scrambling code. A plurality of first masking sections each shift the first m-sequence, and a plurality of second masking sections corresponding to the respective first masking sections each shifts the second m-sequence. A plurality of second summers each adds one of the first shifted m-sequences with the second m-sequence corresponding to the first m-sequence. The output of the second summers thus generates the multiple secondary scrambling codes. <IMAGE>
Patent DE-60023687-T2 (DE)
Inventor: BRAUN WARREN L
IPC: H04H20/67
Filed: 2000-05-22
Granted: 2006-08-24
Abstract: Interference effects between television transmitters for amplitude modulated or digital video and operating on a common allocated channel or frequency is avoided while discrimination is improved by synchronizing carrier signals for a plurality of transmitters. Booster transmitters for correcting coverage anomalies can operate of the same channel or frequency rather than requiring a different channel or frequency presently required in translators; making all allocable channels available for diverse broadcast programming. Discrimination between transmitters operating on the same channel or frequency but with potentially differing programming can be achieved with directional antennas. Synchronization of carrier signals is achieved by frequency multiplication of a tone relayed over a microwave transmission channel by an integral power of two using one or more serially connected full-wave rectifier stages and tuned filters.
Patent DE-60024017-T2 (DE)
Inventor: HAMPL VLADIMIR
IPC: A24D1/02
Filed: 2000-09-12
Granted: 2006-07-27
Abstract: The present invention is directed to a method for improving the ash characteristics of a paper wrapper for a smoking article and for improving the ash characteristics of the smoking article itself. Specifically, it has been unexpectedly discovered that the ash cohesiveness of a paper wrapper is noticeably improved when carbon fibers having an average length less than about 0.75 inches are incorporated into the paper in an amount up to about 60% by weight. Paper wrappers made with carbon fibers in accordance with the present invention have superior ash characteristics in comparison to paper wrappers incorporating only flax or other cellulosic fibers. Further, the ash cohesiveness of the paper is improved without resulting in the decline in the quality of other ash characteristics.