baber/WOPTO huggingface dataset:
Patent PL-1859665-T3 (PL)
Title: Towed agricultural implement with large working width
Inventor: THIELICKE RENÉ
IPC: A01B73/02
Filed: 2007-05-18
Abstract: The equipment has a motor actuating element arranged between a centre frame and a pivoting frame (16) that is pivoted by the element around 90 degrees in an upright position. Side frames (5, 6) are joined laterally to the pivoting frame by rotatable hinges (18), where the side frames are tiltable in relation to the pivoting frame and the centre frame by the element. An intermediate frame (20) is arranged between the pivoting frame and the respective side frame by the hinges, where pivot axes (19) of the hinges run in a lying position of the pivoting frame in a driving direction (15).
Patent PL-2219480-T3 (PL)
Title: Adjustable reservoir for rod-like articles
Inventor: FALLON GARY
IPC: B65G47/51
Filed: 2007-12-17
Abstract: An adjustable reservoir for articles such as smoking articles and smoking article filters comprises a plurality of conveyors mounted one above another in a vertical stack, each conveyor comprising an endless belt defining a curved conveying path of constant radius extending between two ends proximally spaced to define a gap through which articles carried by the belt may drop, and a drive mechanism operable to rotate at least one conveyor about the vertical axis of the stack so as to change the angular position of the gap of that conveyor relative to the gaps of adjacent conveyors. Changing the relative angular positions of the gaps allows the capacity of the reservoir to be adjusted, and further adjustment can be achieved by changing the direction of travel of the conveyor belts. The drive mechanism can be configured to move one or more groups of conveyors in unison, or to move each conveyor individually.
Patent PL-2025810-T3 (PL)
Title: Railway renewing machine with triple separated spoil
Inventor: KONECNY DIETRICH
IPC: E01B27/10
Filed: 2008-08-15
Abstract: The construction has an excavating chain front (10) which provides a first upper layer of the substructure. A rear digging chain (80) is directed to work behind the front digging chain and arranged below the first upper layer. A second transfer body (70) is arranged in the direction of work after the first injection and compression facility is provided and dumps ballast. A digging chain (30) is arranged between the front and rear of the excavating chain to ensure that between the first upper layer and lower layer an intermediate layer is provided.
Patent PL-2261337-T3 (PL)
Title: Dna-sequence and recombinant production of group 4 major allergens from cereals
Inventor: FIEBIG HELMUT
IPC: A61K38/095
Filed: 2004-12-01
Abstract: DNA molecules (I), corresponding to the sequence of the major allergens of cereal pollen are new. (I) have sequences (1; 1603 nucleotides (nt)); (3; 1644 nt); (5; 1608 nt); (7; 1603 nt) or (9; 1603 nt), all reproduced. DNA molecules (I), corresponding to the sequence of the major allergens of cereal pollen comprise sequences comprising 1603 nucleotides (SEQ ID No.:1) (nt)); 1644 nucleotides (SEQ ID No.:3; ); 1608 nucleotides (SEQ ID No.:5; ); 1603 nucleotides (SEQ ID No.:7; ) or 1603 nucleotides (SEQ ID No.:9; ). Independent claims are also included for: (1) DNA (Ia) that hybridizes to (I) under stringent conditions and is derived from DNA of Poaceae; (2) DNA (Ib) that encodes a polypeptide that is immunologically cross-reactive with the major allergens Sec c 4 ( Secale cereale); Hor v 4 ( Hordeum vulgare) or Tri a 4 ( Triticum aestivum) and derived from Poaceae; (3) DNA fragment, or combination of fragments, of (I), (Ia) or (Ib) that encodes an immunomodulatory T-cell reactive fragment (X) of Group 4 Poaceae allergens; (4) a DNA corresponding to any of the new DNAs or fragments that encodes an (X) but is modified by targeted mutation of individual codons, deletion or addition; (5) recombinant DNA expression vector or cloning system containing any of the new DNAs linked to expression control sequences; (6) host organism transformed with any of the new DNAs or the vector of (5); (7) preparing a polypeptide (II) encoded by the new DNAs by culturing the organisms of (6); and (8) (II) having any of the sequences, comprising 518 amino acids (SEQ ID No.:2; 520 amino acids (SEQ ID No.:4; ); 518 amino acids (SEQ ID No.:6; ); 518 amino acids (SEQ ID No.:8) or 518 amino acids (SEQ ID No.: 10; ) or their mature forms. ACTIVITY : Antiallergic. No biological data given. MECHANISM OF ACTION : Vaccine.
Patent PL-2270459-T3 (PL)
Title: Method and apparatus for continuously monitoring interstitial regions in gasoline storage facilities and pipelines
Inventor: KENNEY DONALD P
IPC: G01M3/28
Filed: 2006-09-21
Abstract: An underground storage system includes a primary containment unit and a secondary containment unit arranged to sealingly encompass the primary containment unit. The underground storage system further includes a leak detection system which is fluidly connected to the secondary containment system, and which is adapted to detect fluid leaks in the primary containment system and the secondary containment system.
Patent PL-2435221-T3 (PL)
Title: Device for cutting food articles and multifunction device for the kitchen.
Inventor: REPAC CEDOMIR
IPC: B26D7/18
Filed: 2010-05-28
Abstract: The device (100) has a cutting part (2) and an actuating part (3), where the cutting part has multiple cutters (1). The cutting part and the actuating part are supported in a pivoting manner against each other and the actuating part is pressed against the cutting part for cutting the goods to be cut. The actuating part has a stamp which presses the goods to be cut through the cutting part. A cover part (5) is attached to a receiving container (6) for sliced goods. The receiving container is made up of plastic or glass. An independent claim is also included for a multifunctional equipment with an opening boundary.
Patent GR-3002538-T3 (GR)
Title: Crystal modification of 3-methoxy-4-(4'-amino benzolsulfonamido)-1,2,5-thiadiazole, process for its production and pharmaceutical compositions containing it
Inventor: BURGER ARTUR MAG DR
IPC: C07D285/10
Filed: 1990-11-23
Abstract: The crystalline hemihydrate of 3-methoxy-4-(4-aminobenzene- sulphonamido)-1,2,5-thiadiazole (sulfametrole) and pharmaceutical compositions which contain this compound and are active against bacterial infections and the use of the compound for combating bacterial infections. <IMAGE>
Patent GR-3003058-T3 (GR)
Title: Pessary
Inventor: DROGENDIJK ARIE COSTIAAN
IPC: A61B17/42
Filed: 1991-11-04
Abstract: Pessary particularly applicable in the treatment of prolapses of internal female sex organs, which pessary is formed by a ring-shaped member constructed of such material or such materials that the ring can be deformed by hand to any given shape and the circumferential dimension of the ring can be increased or decreased to some extent by hand, after which the ring retains the ultimately given shape and circumferential dimension. Preferably the ring (1) consists of a core (4) which has the shape of a spiral of non-resilient nature and a flexible casing (5) enclosing said core (4).
Patent GR-3005058-T3 (GR)
IPC: C07F9/40
Filed: 1992-06-30
Abstract: Novel hydroxyalkylesters of N-phosphonomethylglycine have been identified which prove to be effective gametocides.
Patent GR-3005074-T3 (GR)
IPC: C04B35/65
Filed: 1992-07-01
Abstract: A method is disclosed for producing a ceramic body by oxidation of a parent metal, the ceramic body having a graded microstructure characterized by a plurality of zones differing from each other in one or more properties. The zones in the ceramic body are attained by altering the process conditions during formation of said ceramic body such that a zone of the oxidation reaction product formed posterior to said altering has one or more properties different from a zone of the oxidation reaction product formed anterior to said altering.
Patent GR-3006191-T3 (GR)
IPC: F21V33/00
Filed: 1992-11-06
Abstract: In a curtain lighting employing a light source which consists of one or more capped incandescent lamps that are preferably constructed as fluorescent tubes, a downwardly acting translucent screen which shields the light source and combines in one structural unit at least one transparent curtain rail, light-transmitting strips and profiled mounting strips, one or more diaphragms which are constructed as light-transmitting plates, and a mount for the screen, which has resilient metal sections in which the screen can be inserted and from which it can be removed together with its mounting strips, the invention provides for the metal sections of the screen mounting to be constructed in limbs of an open box section, of which the web joining the limbs serves as ceiling unit and forms inside an inwardly open mounting rail for the cap of the light source, whose incandescent lamps or fluorescent tubes are accommodated in each case in a space enclosed by the cap, one of the section limbs, the section web and the screen covering the cap, the metal sections of the mount being constructed on the inside of the box section limbs as profiled strips which form a structural unit with the section limb, while one or both box section limbs have on their outside directly at the junction into the section web a continuously profiled section which forms a mount for a diaphragm. <IMAGE>
Patent GR-3007599-T3 (GR)
IPC: C07D471/22
Filed: 1993-04-09
Abstract: A compound selected from the group consisting of all possible isomeric forms, optically active isomers and racemic mixtures of compounds of the formula    <IMAGE>  I  wherein R1 and R2 are individually selected from the group consisting of hydrogen, halogen, alkyl and alkoxy of 1 to 5 carbon atoms, -OH, -CF3 and -NO2, R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, aralkyl of 7 to 12 carbon atoms, benzoyl and acyl of an alkanoic acid of 1 to 12 alkyl carbon atoms and   <IMAGE>  is selected from the group consisting of   <IMAGE> +TR   <IMAGE>  and their non-toxic, pharmaceutically acceptable acid addition salts having analgesic activity as well as cerebral oxygenating and vaso regulating activity.
Patent GR-3007311-T3 (GR)
IPC: A01N43/54
Filed: 1993-03-11
Abstract: A herbicidal composition comprising, as active ingredients, a compound represented by the following formula I: <CHEM> and at least one compound selected from 2-chloro-4- alpha -chloro-2 min 6 min -diethyl-N-methoxymethylacetanilide (common name: alachlor) or 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl) acetamide (common name: metolachlor). The composition according to the invention can control completely annual weeds as well ds perennial weeds at a lower dose without having phytotoxicity on corn.
Patent GR-3017208-T3 (GR)
Title: Tomatoes.
Inventor: BRIDGES IAN GEORGE
IPC: A01H5/08
Filed: 1995-08-24
Abstract: Fruit, especially tomatoes, having lowered expression of fruit-softening enzymes caused by antisense gene expression, and seeds therefrom.
Patent GR-3017002-T3 (GR)
Title: Compositions for increasing the image contrast in imaging of the digestive tract of patients.
Inventor: TOURNIER HERVE
IPC: A61K49/00
Filed: 1995-08-02
Abstract: Suspensions of echogenic particles in aqueous bioadhesive carriers effectively improve imaging by echography of the digestive tract. Affinity of the compositions for the gastric mucosa can be adapted to the needs by appropriately selecting the carrier in function to its inherent bioadhesive capacity.
Patent GR-3017561-T3 (GR)
Title: Improved adhesive composition and structures manufactured using such adhesive.
Inventor: SCHAAF CECIL F
IPC: C04B24/26
Filed: 1995-09-28
Abstract: This invention deals with an improved adhesive additive, adhesion compositions, articles, and structures manufactured utilizing such adhesive compositions. More specifically, this invention deals with an adhesive additive which is a combination of cement, water, calcium chloride and a curable polymeric latex which when used to bond cementitous substrates, gives bonds with enhanced tensile strengths.
Patent GR-3017663-T3 (GR)
Title: Neuroprotectant agents.
Inventor: CHILDERS WAYNE EVERETT JR
IPC: C07D471/08
Filed: 1995-10-05
Abstract: This invention involves novel neuroprotectant agents of the formula:   <IMAGE>   in which R1 and R3 are, independently, hydrogen, cyano, nitro, halo or perhaloalkyl, with the proviso that one of R1 and R3 is other than hydrogen; R2 is alkyl; or a pharmaceutically acceptable salt thereof.
Patent GR-3017821-T3 (GR)
Title: Cyclic hydroxamic acids and their use.
Inventor: BAECKSTROEM REIJO
IPC: A61K31/40
Filed: 1995-10-19
Abstract: PCT No. PCT/FI91/00123 Sec. 371 Date Oct. 22, 1992 Sec. 102(e) Date Oct. 22, 1992 PCT Filed Apr. 26, 1991 PCT Pub. No. WO91/16303 PCT Pub. Date Oct. 31, 1991.    <IMAGE>  (I)   Substituted cyclic hydroxamic acids of general formula (I) in which R1, R2 and R3are independently hydrogen, halogen, lower alkyl, lower alkoxy, cycloalkoxy, aryloxy which is optionally substituted by 1 to 3 halogen, or aralkyloxy, which is optionally substituted by 1 to 3 halogen, or R1 and R2 together form a -O-CH2-O- group; with the proviso that R3 is not hydrogen when R1 and R2 are both hydrogen; R4 and R5 are independently hydrogen or lower alkyl, R6 is hydrogen or lower alkyl and physiologically acceptable salts and esters thereof are selective inhibitors of phosphodiesterase IV activity and leukotriene B4 and C4 synthesis without showing any significant effect on phosphodiesterase III activity, and are therefore useful in the treatment of hypersensitivity and inflammatory diseases.
Patent GR-3018077-T3 (GR)
Title: A method and a system for drying sludge.
Inventor: BERNES STEEN
IPC: C02F11/13
Filed: 1995-11-15
Abstract: PCT No. PCT/DK91/00175 Sec. 371 Date Feb. 8, 1992 Sec. 102(e) Date Feb. 8, 1992 PCT Filed Jun. 27, 1991 PCT Pub. No. WO92/00250 PCT Pub. Date Jan. 9, 1992.A method and a system serve to completely or partially dehydrate sludge by evaporation which originates from e.g. sewage. The sludge is dried with addition of heat in a drying chamber (2), the sludge being transported on an endless travelling grate (3) from an inlet opening (8) in the drying chamber (2) to a discharge opening (9) in it. The sludge is deposited on the grate in a plurality of juxtaposed sludge strings (18) by means of an extruder (6), in which the sludge is preheated to almost 100 DEG  C. prior to extrusion. The extruded strings (18) are then heated with such an intensity that the water in the sludge immediately begins to boil, and that a zone of preferably saturated water steam is formed at any rate in the immediate vicinity of the sludge. This provides a light and porous, dried sludge product which is in no way either burnt or scorched, and which constitutes excellent fuel as well as excellent compost. The system has a simple and compact construction and is inexpensive to produce, just as it works at moderate operation costs.
Patent GR-3024119-T3 (GR)
Title: Process for upgrading a paraffinic feedstock.
Inventor: VAN BRUGGE PAULUS THEODORUS MA
IPC: B01J29/90
Filed: 1997-07-16
Abstract: Cyclic process for catalytically upgrading a paraffinic feedstock and for upgrading the activity of aged catalyst comprising the steps a) of supplying feedstock and olefin at a paraffin to olefin ratio greater than 5 v/v to a reactor containing a solid acid catalyst and removing effluent comprising upgraded product and b) of exposing the catalyst to a hydrogenating medium and removing a hydrocarbonaceous effluent wherein the catalyst comprises zeolite beta crystals.
Patent GR-3030949-T3 (GR)
Title: Thioxanthenone antitumor agents.
Inventor: WENTLAND MARK PHILIP
IPC: A61K31/67
Filed: 1999-08-10
Abstract: Compounds having anti-tumour activity are disclosed having the formula <CHEM>       wherein: (1) n is 2 or 3;     R<1> and R<2> are independently lower-alkyl; Q is a residue chosen from the group consisting of CH2NHR<3>, CH2N(R<4>)SO2R<7>, CH2NHCHO, CH=N-Ar, C(O)NR<5>R<6>, CH2N(R<4>)C(O)R<7>, CH2N(C2H5)CHO, CH2N(R<4>)P(O)(O-lower-alkyl)2, CH2N=CH-N(R<9>)(R<10>), CH2N(R<4>)C(O)CF3 and CH2N(R<4>)C(O)OR<7>;   R<3> is hydrogen or lower-alkyl;   R<4> is hydrogen, lower-alkyl or Ar;   R<5> is hydrogen, lower-alkyl or Ar;   R<6> is hydrogen or lower-alkyl;   R<7> is lower-alkyl, or Ar;   R<8> is hydroxy; Ar is phenyl or phenyl substituted with methyl, methoxy, hydroxy, halogen or nitro; and   R<9> and R<10> are independently lower-alkyl; or   (2) Q is a residue chosen from the group consisting of CH2N(R<4>)SO2R<7>, CH=N-Ar, C(O)NR<5>R<6>, CH2N(R<4>)C(O)R<7>, CH2N(R<4>)P(O)(O-lower-alkyl)2, CH2N(R<4>)C(O)CF3 and CH2N(R<4>)C(O)OR<7>; R<8> is hydrogen, lower-alkyl, lower-alkoxy, or hydroxy; Ar is phenyl substituted by hydroxy; and n, R<1>, R<2>, R<4>, R<5>, R<6>, and R<7> are as defined hereinabove in part (1) with the proviso that one or more of R<4>, R<5>, or R<7> is Ar; or (3) Q is a residue chosen from the group consisting of CH2N=CH-N(R<9>)(R<10>) and CH2N(R<4>)C(O)CF3 ; R<8> is hydrogen, lower-alkyl, lower-alkoxy, or hydroxy; and n, R<1>, R<2>, R<4>, R<7>, Ar, R<9> and R<10> are as defined hereinabove in part (1), or a pharmaceutically acceptable acid-addition salt or solvate thereof .   Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.
Patent GR-3031277-T3 (GR)
Title: Olefin polymerization catalyst
Inventor: JOB ROBERT CHARLES
IPC: C08F110/06
Filed: 1999-09-22
Abstract: High activity, stereoregular olefin polymerization catalysts are produced from an organoaluminum cocatalyst, a selectivity control agent and a procatalyst obtainable from a magnesium-containing, titanium-containing procatalyst precursor also containing at least one of alkoxide, optionally substituted phenoxide or trialkylborate moieties. The catalysts are useful in the polymerization or copolymerization of lower α-olefins, particularly propylene.
Patent GR-3031428-T3 (GR)
Title: Coin-checking arrangement
Inventor: SEITZ THOMAS
IPC: G07D5/08
Filed: 1999-10-07
Abstract: PCT No. PCT/EP97/01342 Sec. 371 Date Sep. 10, 1998 Sec. 102(e) Date Sep. 10, 1998 PCT Filed Mar. 18, 1997 PCT Pub. No. WO97/35286 PCT Pub. Date Sep. 25, 1997An arrangement for checking coins wherein the coins (1) move in the checking operation along a side wall (6) of a coin passage (2) and past two coil halves (4a, 4b) which are disposed opposite each other on both sides of the coin passage (2) and which are connected in series in phase opposition. The coin half (4b) which is disposed on the same side of the coin passage (2) as the side wall (6) is of lower resistance than the other coin half (4a) and preferably comprises stranded wire.
Patent HR-P20080520-T3 (HR)
Inventor: HORVATH STUPHANE
IPC: C07D223/16
Filed: 2008-11-27
Abstract: Kristalni oblik ß ivabradin hidroklorida formule (I): naznačen time, da je određen sljedećim dijagramom difrakcije X-zraka na prašku, izmjerenim difraktometrom PANalytical X'Pert Pro s detektorom X'Celerator i izraženim u kategorijama položaja crte (Braggov kut 2 theta, izražen u stupnjevima), visine crte (izraženo zbrojem), površine crte (izraženo zbrojem pomnoženo sa stupnjevima), širine crte na polovici visine ("FWHM", izražen u stupnjevima) i interplanarne udaljenosti d (izraženo u A):
Patent GR-3032836-T3 (GR)
Title: Acridone-derived bisintercalators as chemotherapeutic agents
Inventor: MICHEJDA CHRISTOPHER J
IPC: A61K31/473
Filed: 2000-02-29
Abstract: The present invention provides an anticancer compound having the structure:   <IMAGE>  +TR   <IMAGE>independently -H, -OH, -NH2, -OCH3, -C(CH3)3, or a halogen atom; n is 2 to 6; X and X' are independently -N or -NO2; Y and Y' are independently -N, -CH, or -H; and the double-slash represents a double bond or no bond; such that when X or X' is -N, Y or Y' is -CH or -N, and the double-slash is a double bond, and when X or X' is -NO2, Y or Y' is -H, and the double-slash is no bond. The present invention also provides a pharmaceutical composition comprising the compound above and a pharmaceutically acceptable carrier.
Patent GR-3034474-T3 (GR)
Title: Continuous casting ingot mould for the vertical casting of metals
Inventor: JOLIVET JEAN-MARC
IPC: B22D11/055
Filed: 2000-09-25
Abstract: PCT No. PCT/FR97/00547 Sec. 371 Date Jan. 22, 1999 Sec. 102(e) Date Jan. 22, 1999 PCT Filed Mar. 27, 1997 PCT Pub. No. WO97/37793 PCT Pub. Date Oct. 16, 1997The mold comprises a tubular metal component (4), made of copper or a copper alloy, cooled by water circulation against its external wall and intended to ensure that the cast metal undergoes peripheral solidification on contact with its internal wall, and an uncooled feed head (9) made of a thermally insulating refractory, intended to contain cast metal in the liquid state and sitting on top of the cooled metal component (4) and defining with it a continuous sizing passage for the cast metal. A horizontal metal annulus (16) cooled by internal circulation is added between the feed head (9) and the tubular component (4) and aligned with the internal wall of the latter.
Patent GR-3034814-T3 (GR)
Title: Crystal form of N-(4-trifluoromethylphenyl)-5-methylisoxazole-4-carboxamid
Inventor: FAASCH HOLGER DR
IPC: C07D261/18
Filed: 2000-11-10
Abstract: Crystal modification 2 of N-(4-trifluoromethylphenyl)-5-met hylisoxazole-4-carboxamide (I) (leflunomid; HWA 486) is new. - New crystal modification 2 of N-(4-trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide (I) has lines (diffraction angles 2theta ([deg])) of strong intensity at 10.65, 14.20, 14.80, 16.10, 21.70, 23.15, 24.40, 24.85, 25.50, 25.85, 26.90 and 29.85 and of medium intensity at 7.40, 9.80, 13.10, 15.45, 16.80, 20.70, 21.45, 22.80, 23.85, 27.25 and 28.95 in the X-ray diffraction graph using Cu-Kalpha 1 radiation in the focusing Deybe-Scherrer procedure and transmission. Compound (I) is known from US 4284786. Independent claims are included for: (A) the preparation of crystal modification 2; and (B) the preparation of crystal modification 1 of compound (I) having lines of strong intensity at 16.70, 18.90, 23.00, 23.65 and 2.05 and lines of medium intensity at 8.35, 12.65, 15.00, 15.30, 18.35, 21.55, 24.10, 24.65, 25.45, 26.65, 27.40, 28.00 and 28.30 in the X-ray diffraction graph measured and defined in the same manner as for crystal modification 2. -
Patent GR-3035149-T3 (GR)
Title: Chimeric and/or growth-restricted flaviviruses
Inventor: LAI CHING-JUH
IPC: A61K39/12
Filed: 2000-12-27
Abstract: The invention includes a chimeric virus for use in a vaccine preparation having a genome comprising nucleic acid sequences encoding at least one structural protein from one flavivirus and nucleic acid sequences encoding nonstructural protein from another flavivirus. The genome preferably includes mutations within the viral genome that reduce virus virulence and in a particularly preferred embodiment these vaccines are directed to flaviviruses such as dengue virus, tick-borne encephalitis virus and Japanese encephalitis virus.
Patent GR-3036599-T3 (GR)
Title: Injectable depot gel composition and method of preparing the composition
Inventor: BRODBECK KEVIN J
IPC: A61K47/34
Filed: 2001-09-12
Abstract: Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10% or less of the total dose of beneficial agent in the first 24 hours after implantation for local applications. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
Patent DE-69102893-T4 (DE)
Inventor: BUTLER TODD WILLIAM
IPC: C07D405/04
Filed: 1991-01-24
Granted: 1995-08-10
Abstract: 3-piperidino-4-hydroxychroman derivs. of formula (I) and their salts are new, where A and B = H or A with B = -CH2CH2-. X = CH2 or O. X1 = H or OH. Z = H, F, Cl, Br or OH. Z1 = H, F, Cl, Br or 1-3C alkyl. n = O or 1; m = 0 or 1-6. When X = 0 (I) pref has cis stereochemistry. (I) are prepd. by hydride redn. of a suitable alpha-aminoketone, using e.g. NaBH4 in THF at -15 to 15 deg.C.