baber/WOPTO huggingface dataset:
Patent MA-52676-A1 (MA)
Title: Compositions et procédés d’élimination des métaux lourds des flux contenant de l’acide phosphorique
Inventor: ZHANG LEI
IPC: C01B25/238
Filed: 2021-03-02
Abstract: L’invention fournit des compositions et des procédés pour éliminer/récupérer des ions de métaux lourds dans des solutions contenant de l’acide phosphorique par addition de réactifs contenant au moins un composé organothiophosphoré et au moins un composé de 2- mercaptobenzothiazole à une solution ou suspension d’acide phosphorique par voie humide pour former des complexes d’ions de métaux lourds, et pour séparer les complexes d’ions de métaux lourds de la solution.
Patent MA-54635-A1 (MA)
Title: 3-[2-(2-amino-1h-benzimidazol-1-yl) éthyl]-1,3-oxazolidin-5 2-one comme composé presentant une activité sélective vis-a-vis la sous unité alpha 2 du récepteur gaba? Pour le traitement de l’anxieté et la dépression.
Inventor: EL MOKHTAR ESSASSI
IPC: A61P25/24
Filed: 2021-10-11
Abstract: L'invention concerne la 3-[2-(2-aminobenzimidazol-1-yl)éthyl]-1-3-oxazolidin-2-one, des compositions pharmaceutiques la renfermant, et des procédés de traitement y faisant appel. Ce composé est utile dans le traitement des maladies et des troubles du système nerveux central qui réagissent à la modulation du complexe récepteur gabaa. Ce composé présente une activité puissante et sélective sur la sous unité alpha 2 du récepteur gabaa et peut en tant que tel, être utile pour le traitement de l’anxiété et la dépression.
Patent MA-56085-A1 (MA)
Title: Mélange d'oligo-éléments moyens superabsorbants et application associée
Inventor: WANG RENZONG
IPC: C05G3/00
Filed: 2020-11-02
Abstract: La présente invention concerne un mélange d'oligo-éléments moyens superabsorbants et une application associée. Le mélange d'oligo-éléments moyens superabsorbants comprend 50 à 95 % de soufre, 0,5 à 20 % d'un agent de dispersion, et 0,1 à 45 % d'oligo-éléments moyens autres que le soufre. Un procédé de préparation comprend : l'ajout des oligo-éléments moyens et d'un agent de dispersion à du soufre liquide, et le mélange homogène de ceux-ci. Le procédé de préparation peut être appliqué à la préparation d'un mélange d'oligo-éléments moyens granulaires et à l'enrobage d'engrais granulaires. La présente invention présente les avantages suivants : le mélange d'oligo-éléments et d'éléments moyens est uniforme, stable, facile à transporter et peut être personnalisé en fonction des exigences du client, et les oligo-éléments moyens peuvent être ajoutés rapidement et de manière flexible.
Patent UY-23473-A1 (UY)
Title: Procedimiento para la preparacion de derivados del acido biciclico carboxilico
Inventor: COHEN NOAL
IPC: A61P17/06
Filed: 1992-09-09
Abstract: Se describe un procedimiento para la preparación de compuestos de la fórmula general I (figura 1) en donde R1 es cicloalquilo, entre otras posibilidades; B es una fracción aromática o heteroaromática mono-, di- o tricíclica sustituida por el grupo -COR2, entre otras posibilidades. Como ejemplo no limitante: ácido 2-(4-carboxibutoxi)-6-[6-[(3,4-dihidro-4-oxo-8-propil-2H-1-benzopiran-7-il)oxi]hexil]bencenpropanoico. Su uso es en el tratamiento de enfermedades inflamatorias, tal como psoriasis, enfermedad inflamatoria de los intestinos, asma, alergia, artritis, dermatitis, gota, afección pulmonar, lesión por isquemia/reperfusión, e inflamación inducida por trauma, tal como lesión de la médula espinal.
Patent UY-24407-A1 (UY)
Title: Procedimiento para la preparacion de compuestos para el tratamiento de la patologia de reacciones adversas
Inventor: CLAIRMONT G DRUBE
IPC: A61K9/34
Filed: 1996-12-13
Abstract: La presente invención se refiere a un método para fabricar una diglucosilamina que afecta al sistema de control de inflamaciones, el cual comprende los pasos de: a) hacer reaccionar glucosa, una base que contiene nitrógeno, y metanol o etanol, para formar una diglucosilamina; y b) recuperar la diglucosilamina. El método comprende los pasos de: a) hacer reaccionar D-(+)-glucosa, una base acuosa que contiene nitrógeno, y ya sea metanol o etanol, para formar glucosilamina; b) evaporar el metanol o el etanol para formar una fase acuosa; c) agregar una pasta acuosa de carbón a la mezcla con agitación para absorber la diglucosilamina sobre el carbón; d) separar el carbón del agua; y e) recuperar la diglucosilamina. El compuesto preferido para el tratamiento de reacciones inflamatorias adversas es di-Beta-D-glucopiranosilamina.
Patent UY-26371-A1 (UY)
Title: Imidazo-3-il-aminas biciclicas, procedimiento para su preparacion y medicamentos que las contienen
Inventor: GERLACH MATTHIAS GERLACH MATTH
IPC: A61K48/00
Filed: 2000-10-05
Abstract: Imidazo-3-il-aminas bicíclicas de la fórmula general I en forma de sus bases o sales farmacéuticamente aceptables, procedimiento para su preparación y medicamento que contiene como sustancia activa al menos una amidazol-3-il-amina bicíclica de la fórmula general I en forma de su base o una sal farmacéuticamente aceptable.
Patent UY-29227-A1 (UY)
Title: Composiciones farmacéuticas sólidas que comprenden una combinación de drospirenona, etinilestradiol y un agente surfactante adecuado que presentan una homogeneidad de contenido y velocidad de disolución asegurada para la droga no micronizada, procedi
Inventor: ANDRADE GUSTAVO
Filed: 2005-11-24
Abstract: La presente invención se relaciona con una composición farmacéutica asegurando una velocidad de disolución y homogenización de la droga no micronizada logrando una estabilidad físico-química inesperada.También con la composición farmacéutica obtenida por ese proceso y el uso de la composición farmacéutica para preparar un medicamento. La composición farmacéutica comprende, una combinación de dos principios activos, a saber drospirenona y etinilestradiol, un agente surfactante y excipientes farmacéuticamente aceptables con la condición de que la drospirenona presente la siguiente distribución: aproximadamente el 95% de ellos presenten un tamano de partícula inferior a 100 um (micrómetros), aproximadamente el 26 % presente un tamano de partícula inferior a 20 um (micrómetros) y aproximadamente el 15% presente un tamano de partícula inferior a 10.00 um (micrómetros), o con la condición de que dichos principios activos presenten una área superficial menos a 10000cm2/g o con la condición que la drospirenona no se encuentra en forma micronizada. Esta composición es usada para inhibir la ovulación y los cambios en la secreción cervical.
Patent UY-30276-A1 (UY)
Title: Dimeros de derivados de artemisinina, su preparacion y su aplicacion en terapéutica
Inventor: AUGUSTIN HITTINGER
IPC: A61P35/00
Filed: 2007-04-11
Abstract: La presente invencion se refiere a nuevos dímeros de derivados de artemisinina específicos, su preparacion, composiciones que los contienen y su utilizacion como medicamentos, en particular como agentes anticancerígenos.
Patent UY-30380-A1 (UY)
Title: Teléfono glucoestres móvil
Inventor: VERRI LIMA GASTON JERONIMO
IPC: A61B5/0205
Filed: 2007-05-31
Abstract: El teléfono Glucoestres Móvil es un aparato caracterizado por un teléfono móvil o teléfono celular o dispositivo de comunicación móvil integrado a uno, dos, tres o cuatro de los siguientes analizadores: A) analizador de glicemia, B) analizador de tensión transcutánea de oxígeno, C) analizador de actividad electrocardiográfica y frecuencia cardíaca, y D) analizador de presión arterial y frecuencia de pulso. Cada analizador mencionado cuenta, o podrán contar, con uno o más sensores y transductores inalámbricos con fuente de energía y de emisión de senal precodificada y además tienen la potencialidad de conectarse por cable con el Teléfono Glucoestres Móvil.
Patent UY-30481-A1 (UY)
Title: Isoxazolinas sustituidas, composiciones farmaccuticas que contienen a las mismas, metodos de preparacion y usos.
Inventor: TATAMIYA TAKAYUKI
IPC: C07D333/38
Filed: 2007-07-11
Abstract: Isoxazolinas sustituidas que responden a la formula general (I): en donde A, R1, R2, R3, R4, Z, X, m, n, y p, tienen los valores que se indican en las reivindicaciones, y sus sales, composiciones farmacéuticas que comprenden dichas isoxazolinas sustituidas, métodos para preparar dichas isoxazolinas sustituidas así como su uso para la elaboracion de una composicion farmacéutica para el tratamiento de enfermedades mediadas al menos parcialmente por actividad de HDAC o cuyos síntomas son aliviados por los inhibidotes HDAC:
Patent ZW-16284-A1 (ZW)
Title: New n-(thio)carbamoylaryl(thio)carboximidic acid esters,a process for their preparation,agents containing them and their use as pest control agents
Inventor: VOLKER KOCH
IPC: A01N37/52
Filed: 1984-09-20
Abstract: The compounds of the formula I    <IMAGE>  (I)  in which R1 to R5 denote hydrogen; alkyl, alkoxy, alkylmercapto, alkylsulfinyl, alkylsulfonyl, alkylsulfonyloxy each of which can be halogenated, halogen or nitro, R6 to R10 denote hydrogen; alkyl, alkoxy, alkenyloxy, alkylmercapto, alkenylmercapto, alkylsulfonyl or C3-hydroxyalkyl each of which can be halogenated, (substituted) benzyloxy, alkoxycarbonyl or NRR', and R7 and R8 together can form a (substituted) alkylenedioxy radical, X denotes OR11 in which R11 denotes optionally halogenated alkyl, cycloalkyl, alkenyl or alkynyl or optionally halogenated benzyl, or SR12 in which R12 denotes alkyl or benzyl each of which can be halogenated, and Y denotes oxygen or sulfur, subject to the proviso that, if R1 and R5 both denote fluorine and R2, R3 and R4 denote hydrogen, the radicals R6 to R10 must not each represent halogenated (C1-C6)-alkyl or halogen, possess an intense action against a broad spectrum of harmful insects.
Patent AT-500150-A1 (AT)
Title: Rotary cutting tool has side apertures adjacent to teeth leading to central chamber
IPC: B23C5/10
Filed: 2003-01-09
Abstract: A rotary cutting tool has a shank (3) terminating in a front end (2) with a number of teeth (1) defining frontal cutting edges and side cutting edges. The front end (2) esp. has elongated openings (4) in line with the teeth (1). The openings (4) lead to an axial hollow chamber linked to an outlet at the front end. The openings provide an outlet for swarf or shavings.
Patent ES-184110-A1 (ES)
Title: UN APARATO PARA EL SUMINISTRO, UNO A UNO, DE MONDADIENTES, CIGARRILLOS Y, EN GENERAL, SoLIDOS DE FORMA ALARGADA
Filed: 1948-06-14
Abstract: Un aparato para el suministro uno a uno de mondadientes cigarrillos y en general de sólidos en forma alargada esencialmente constituido por un cuerpo a modo de depósito en el que aquellos quedan establecidos horizontalmente convergiendo transversalmente el fondo de dicho depósito hacia una abertura que abarca toda su anchura y que cierra un cilindro que parcialmente penetra en el mismo susceptible de girar provisto de unas estrías con hendiduras longitudinales en cada una de las cuales pueda alojarse una unidad del objeto de que se trate en cada caso y en esta forma al hacer girar desde el exterior el mencionado cilindro arrastra fuera del depósito la unidad que se haya alojado en cada una de tales estrías.
Patent ES-191014-A1 (ES)
Title: MáQUINA PARA DIVIDIR, EN PORCIONES DE PESO O VOLUMEN DETERMINADO, UNA MASA PASTOSA O SEMIPASTOSA, TAL LA MASA DEL PAN
Filed: 1949-12-16
Abstract: Máquina para dividir en porciones de peso o volumen determinado una masa pastosa o semipastosa tal la masa de pan caracterizada por un tambor rotatorio al que se imprime movimiento de giro intermitente es decir alternando paros y giros de un cierto ángulo y que presenta en su periferia unas cavidades construidas por otras tantas canales longitudinales dentro de las que se desplazan unos correspondientes émbolos cuyo movimiento se produce con el giro del tambor y que en su carrera de avance llegan hasta la boca de la canal para retroceder luego en movimiento lineal alternativo y con paros o detenciones en su carrera cuan menos los correspondientes a los paros del tambor en su movimiento de giro intermitente.
Patent ES-275477-A1 (ES)
Title: Improvements in or relating to the treatment and preservation of animal tissue
IPC: A61K35/32
Filed: 1962-03-14
Abstract: Animal tissue is extratced with a non-ionic surfactant solution, is extracted with a fat solvent, is extracted with a non-ionic surfactant solution and is then washed with water it is stated that the thus-treated tissue is more likely to be compatible with a tissue to which it is subsequently grafted and is far easier to store for long periods. In a preferred procedure, animal bone is exercized under sanitary conditions, the bone is soaked in a sterilising solution of about 0.5 to 5.0% salt concentration, the bone is extracted with an aqueous surfactant solution containing about 0.5 to 2.0% of a pastial ester of a higher unsaturated fatty acid with an anhydride of a polyhydroxy alcohol surfactant, the bone is extracted with chleroform-methanol solution for about 20 to 30 hours, the bone is extracted with a further non-ionic aqueous surfactant solution, the bone is washed with continuously changing water for about 48 to 200 hours, and the washed bone is sterilized and then byophilized. Animal tissue includes bone, cartilage, tendon or fascia. Fat solvents: chloroform, acetone, lower aliphatic alcohols such as methanols or mixtures of these. Surfactants: partial esters of higher unsaturated fatty acids with anhydrides of polyhydroxy alcohols and polyoxyethylene derivatives thereof, particularly sorbitan mono-oleate polyoxyethylene and specified proprietary products. For sterilisation there may be employed inter alia solutions containing, liquid b -propiolactone, or cathode irradiation. Examples disclose detailed procedures.
Patent ES-337351-A1 (ES)
Title: Antistatic thermoplastic copolymers
IPC: C08L55/02
Filed: 1967-02-28
Abstract: A moulding composition comprises (I) a graft copolymer of styrene and acrylonitrile, or their alkyl derivatives, on a polymer of a conjugated diene comprising at least 80% polymerized diene and at most 20% styrene, acrylonitrile, an alkyl styrene, an alkyl acrylonitrile or a mixture thereof and (II) (a) a copolymer of a conjugated diene with an ester and/or nitrile of an ethylenically unsaturated carboxylic acid and (b) an optionally etherified or esterified polypropylene glycol with a degree of polymerization of from 10 to 1000. The composition may contain styrene-acrylonitrile copolymer additional to that present in graft polymer (I) and copolymer (II) (a) may contain acrylic or methacrylic acid. The diene present in polymers (I) and (II) is, e.g., butadiene alone or a mixture of butadiene and isoprene. The ester or nitrile of copolymer (II) (a) may be derived from acrylic acid, methacrylic acid or fumaric acid. The compositions are preferably prepared by mixing an aqueous emulsion of the polypropylene glycol with aqueous latices of the copolymers and coagulating the mixture. In examples, copolymer (I) comprises styrene and acrylonitrile grafted on to polybutadiene or a butadiene-styrene copolymer, copolymer (II) (a) comprises butadiene copolymerized with n-butyl acrylate, ethyl acrylate, di-n-butyl fumarate, methyl methacrylate or a mixture of (i) methyl methacrylate and methacrylic acid, (ii) methyl methacrylate, acrylonitrile and methacrylic acid, or (iii) acrylonitrile and methacryilc acid, and component (II) (b) is a linear or branched polypropylene glycol, polypropylene glycol monomethyl ether or polypropylene glycol diacetate. The compositions also contain a copolymer of acrylonitrile and styrene or alpha-methyl styrene.
Patent ES-348509-A1 (ES)
Title: N'-substituted n-arylsulphonyl ureas
IPC: C07C51/60
Filed: 1967-12-21
Abstract: Novel compounds I (including salts thereof) of the general formula wherein R 1 signifies H, F, Cl, Br, NH 2 , alkyl, alkoxy, alkylthio or alkanoyl, R 2 signifies H or R 1 R 2 signifies -(CH 2 ) 3 - or -(CH 2 ) 4 -, are prepared: (a) by reacting octahydro-1,2,4- methenopentalene-5-amine (obtained by hydrolysis of the corresponding 5-acetamido compound via the hydrochloride) with an appropriate substituted benzenesulphonyl isocyanate or with a reactive derivative of an appropriately substituted benzenesulphonyl carbamic acid (the substituents include, in addition to those listed under R 1 , R 2 and R 1 R 1 substituents which can be converted into the amino group by hydrolysis, reduction or reductive cleavage) (b) by reacting isocyanic acid-(octahydro-1,2,4- methenopentalen-5-yl ester) (obtained by treating octahydro - 1,2,4 - methenopentalene - 5 - carbonyl chloride, derived from the acid, with sodium azide with heating) or a reactive functional derivative of [octahydro-l,2,4-methenopentalen-5-yl)-carbamic acid with the appropriate benzenesulphonamide {substituents as in (a)} or (c) by desulphurizing corresponding thioureas {substituents as in (a)} the products obtained from methods (a), (b) and (c) may, if necessary, be hydrolysed or reduced. N - (Octahydro - 1,2,4 - methenopentalen - 5 - yl)- acetamide is prepared from the foregoing isocyanic acid ester by boiling with a mixture of glacial acetic acid and acetic anhydride. (Octahydro - 1,2,4 - methenopentalen - 5 - yl) carbamic acid methyl ester is obtained by heating the foregoing isocyanic acid ester with methanol while refluxing the carbamic acid ester may be converted to the 5-amine referred to in (a) by boiling with aqueous potassium hydroxide. Octahydro - 1,2,4 - methenopentalen - 5 - carboxamide, obtained from the corresponding 5-carboxylic acid ethyl ester by treatment with 26% aqueous ammonia, also affords the carbamic acid methyl ester by treatment with sodium methylate/methanol followed by bromine. (Octahydro - 1,2,4 - methenopentalen - 5 - yl)- urea is prepared from the foregoing isocyanic acid ester by reaction with ammonia in tetrahydrofuran the use of methylamine or dimethylamine in place of ammonia affords corresponding urea derivatives. 1 - (p - Tolylsulphonyl) - 3 - (octahydro - 1,2,4- methenopentalen - 5 - yl) - thiourea is produced by the interaction of p-tolylsulphonyl isothiocyanate and octahydro-1,2,4-methenopentalen- 5-amine or by interacting p-tolylsulphonamide and octahydro-1,2,4-methenopentalen-5-yl-isothiocyanate. Pharmaceutical preparations having hypoglycaemic action contain as active ingredient compounds I administration is preferably orally.
Patent ES-351604-A1 (ES)
Title: Improvements to the Production of Cementitious Construction Material
IPC: C04B24/26
Filed: 1968-03-14
Abstract: An emulsion of a copolymer of styrene with methyl acrylate or with ethylhexyl acrylate is included in an aqueous mix containing 75 partsof size-graded sand and 25 parts of Portland cement. 1 to 5 wt. per cent based on the dry weight of the mix of the copolymer is added to a mix containing 6 to 8 wt. per cent of water. Lithium sulphate may be included as a setting accelerator in an amount of 0À5 to 2 wt. per cent based on the cement.
Patent ES-352944-A1 (ES)
Title: Swingable sliding car door assembly
IPC: B60J5/06
Filed: 1968-04-20
Abstract: An outwardly swingable sliding door in a vehicle comprises a door leaf 2 supported on two vertically spaced arms 17 each rigidly secured at one end to a shaft 17a pivotably mounted on the door frame, the other ends of the arms 17 having rollers 18 running in respective recesses 19 in the inner door leaf wall and engaging respective rail webs 20 arranged flush with the inner door leaf wall to partially close the recesses, and an angled guide arm 3a, 3b is pivotally connected to the door at 4, and bears a vertical roller 5 and horizontal rollers 6, 15 running in a first recess 7 which is arranged externally on the vehicle body wall and has a curved end portion 16, the rollers 6, 15 engaging a rail web 8 partially closing recess 7 and flush with the external body wall. At the door leaf edge portion opposite to the edge having the guide arm 3 is a rigid supporting arm 10 having rollers 11, 12 running in a second recess 13 in the body wall below the lower horizintal door frame member, roller 12 engaging a rail web 14 partially closing the recess 13. When the door leaf 2 is closed, which is facilitated by a spring 15a on the guide arm, roller 15 enters portion 16 of recess 7, portion 3a of the guide arm lies flush with the vehicle body external wall and portion 3b lies in the door aperture and is concealed by a door leaf flange 4b, Figs. 4 and 5 (not shown). Roller 5 has a somewhat laterally rounded shape at its circumferential surface to allow easy movement in recess 7.
Patent ES-354289-A1 (ES)
Title: Radiopaque derivatives of alpha-phenoxy-phenylacetic acid
IPC: A61K49/04
Filed: 1968-05-24
Abstract: The invention comprises compounds of the formula in which "alkyl" represents an alkyl C 1-4 radical, "acyl" represents an aliphatic acyl C 2-4 radical derived from a carboxylic acid and "aryl" represents a phenyl, halophenyl or alkylphenyl radical and their non-toxic metal and/or amine salts or their esters with lower C 1-5 alcohols. They are prepared by N-alkylating the corresponding [alpha]-(3-acylamino-2,4,6-triiodo-phenoxy)-arylacetic acid in an alkaline medium with a reactive alkyl ester, or by reacting the corresponding 3 - (N - alkylacylamino) - 2,4,6- triiodophenol with a compound of the formula X.CH(aryl).COOR in which X represents a reactive radical of a strong acid, -COOR represents a carboxylic ester or salt group, in the presence of a basic condensation agent, followed by hydrolysis of the ester, if desired. The [alpha],-(3-acylamino-2,4,6-triiodophenoxy)-aryl acetic acids where aryl represents phenyl, p-iodo phenyl and o, m or p-tolyl are prepared by reacting the corresponding 3-acylamino-2,4,6- triiodophenol with the corresponding [alpha]-bromoaryl acetic acid ethyl ester, followed by hydrolysis of the resultant ethyl ester. 3 - (N - Methylacetylamino) - 2,4,6 - triiodophenol is obtained from the corresponding acetylamino compound and methyl iodide. Pharmaceutical compositions containing compounds of Formula I as X-ray contrast agents together with a pharmaceutically acceptable carrier are administered orally and act as cholecystographic agents.
Patent ES-356908-A1 (ES)
Title: Photolithographic masks and methods for their manufacture
IPC: C23C14/02
Filed: 1968-07-27
Abstract: A transparent substrate is coated with a substantially uniform, pinhole-free coating of a metal by depositing a first layer of metal on the substrate, removing any loosely adhered particles of the metal by subjecting it to a blast of gas, and depositing a second layer of metal on said first metal layer. The substrate may be glass which is coated with a Cr layer 400-600A thick by vapour deposition, the layer is subjected to a blast of air at 60 p.s.i., and then coated with further Cr by vapour deposition to a total thickness of 800-1200 The coated plate may be converted into a mask for use in photo-lithographic processes by application of a photo-resist, removal of exposed metal using HCl, H 2 SO 4 , or H 2 SO 4 and H 3 PO 4 , stopping the etching using NH 4 OH, and removal of the resist.
Patent ES-359874-A1 (ES)
Title: Diuretic sulphamylantranilic acids
IPC: C07D333/20
Filed: 1968-11-05
Abstract: Sulphamylanthranilic acids of formula (I) - R = benzyl, furfuryl or thenyl - Hal = Cl, Br - As diuretic and saluretic agents. - (a) A soln. of 3-sulphamyl-4-chloro-6-fluoro-benzonitrile (23.5 g.) in DMF (50 ml.) is treated dropwise with freshly dist. furfurylamine (21.4 g.), keeping the temp. at 28-30 deg. by cooling addn. of the mixt. to 10% HOAc (500 ml.) gives 3-sulphamyl-4-chloro-6-furfurylamin obenzonitrile (30.5 g.), m.pt. 234-5.5 deg. dec. (237 deg. from MeNO2). - (b) this (9.4 g.), 2N-NaOH (100 ml.) and dioxan (20 ml.) are refluxed for 2 hr. to give 3-sulphamyl-4-chloro-6-furfurylaminobenzoic acid (9.1 g.), dec. 200-3 deg. (205-6 deg. from MeNO2).