baber/WOPTO huggingface dataset:
Patent MX-2019008843-A (MX)
Title: Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers.
Inventor: Hans- Georg RAMMENSEE
IPC: C07K7/08
Filed: 2018-01-26
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Patent MX-2019009915-A (MX)
Title: Antifog sealant composition and coextruded multilayer polyester film including the same.
Inventor: ROBERTO FORLONI
IPC: C09D167/00
Filed: 2018-02-26
Abstract: The invention relates to a sealant antifog composition for polyester films comprising anionic and non- ionic surfactants in a mixture of amorphous and (semi)crystalline polyesters. The invention also relates to a multi-layer film comprising a sealant layer having the above composition, to the use of said films in food packaging and to the packages obtained therefrom.
Patent MX-2019010036-A (MX)
Title: Guardrail crash absorbing assembly.
Inventor: MARCO ANGHILERI
IPC: E01F15/14
Filed: 2017-10-30
Abstract: A guardrail vehicle crash absorbing assembly including a braking structure at a panel joint including a tooth having a cutting portion for making a horizontal cut in a rail panel slidably moving relative to another rail panel.
Patent MX-2019012452-A (MX)
Title: Engineered meganucleases specific for recognition sequences in the pcsk9 gene.
Inventor: JANTZ DEREK
IPC: A61K38/16
Filed: 2018-04-20
Abstract: The present invention encompasses engineered meganucleases which recognize and cleave a recognition sequence within the human PCSK9 gene. The present invention also encompasses methods for using such engineered meganucleases in a pharmaceutical composition and in methods for treating or reducing the symptoms of cholesterol-related disorders, such as hypercholesterolemia. Further, the invention encompasses pharmaceutical compositions comprising engineered meganuclease proteins, nucleic acids encoding engineered meganucleases, and the use of such compositions for treating cholesterol-related disorders, such as hypercholesterolemia.
Patent MX-2020002082-A (MX)
Title: System and method for providing carbon dioxide and circulating air for a vertical gardening system.
Inventor: BOGNER MATTHEW LAWRENCE
IPC: A01G31/06
Filed: 2018-08-24
Abstract: Vertical growing uses a plurality of shelves to support plants. The system has an air filtration and ultraviolet (UV) air purification system. The purified and filtered air is mixed with nitrogen, which is directed towards plants. The system can include lights to help grow the plants placed on the shelves. The filters can remove odors from the circulating air.
Patent MX-2020003043-A (MX)
Title: Methods of detecting transthyretin.
Inventor: NIJJAR TARLOCHAN S
IPC: A61K31/711
Filed: 2018-10-05
Abstract: The invention provides methods of detecting transthyretin (TTR) using a capture antibody and a reporter antibody. The capture antibody binds preferentially to misfolded TTR over native tetrameric form of TTR. The capture antibody binds to an epitope within amino acid residues 89-97 or TTR or to an epitope within amino acid residues 101-109 of TTR. 9D5 and 18C5 are examples of suitable capture antibodies. The methods can be used for diagnosing diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (<i>e.g.</i>, TTR amyloidosis) and for monitoring the efficacy of TTR therapies, among other applications.
Patent MX-2020004972-A (MX)
Title: Use of carbamate compound for preventing, alleviating or treating absence seizure or epilepsy showing absence seizure.
Inventor: SHIN HYE WON
IPC: A61K31/41
Filed: 2018-11-13
Abstract: The present invention relates to a use of a carbamate compound represented by chemical formula 1, or a pharmaceutically acceptable salt, a solvate or a hydrate thereof for preventing, alleviating or treating absence seizure or epilepsy showing absence seizure.
Patent MX-2020005834-A (MX)
Title: Plastic container having an opening means.
Inventor: MÜHLEMANN ROLF
IPC: B65D81/32
Filed: 2018-12-07
Abstract: The invention relates to a plastic container, comprising a container body (1), a container cover (2, 2', 2''), and an opening means (9) for opening the container cover (2, 2', 2''). The container body (1) comprises a container wall (3) and a container bottom (4) arranged in a lower region. A container opening (5) is formed at an upper end of the container body (1) lying opposite the container bottom (4). The container body (1) comprises a peripherally extending upper border (6) in the upper region. The container cover (2, 2', 2'') is fastened to the upper border (6) of the container body (1) in order to cover the container opening. According to the invention, the upper border (6) is connected to the container wall (3) at a distance radially outward from an upper edge (7) of the container wall (3) and by means of a flexible connecting portion (8), the flexible connecting portion (8) permitting sliding of the upper border (6) relative to the container wall (3) and to the opening means (9) such that the plastic container can be brought from a closed position into an open position.
Patent MX-2020010054-A (MX)
Title: Point-of-care diagnostic systems and containers for same.
Inventor: LABAK CHRISTOPHER
IPC: B01L9/00
Filed: 2019-04-08
Abstract: The present disclosure relates to a medical diagnostic system. In various embodiments, the system includes a housing, a first receptacle in the housing for receiving a reagent container, a second receptacle in the housing for receiving a working fluid and waste container, where the second receptacle is larger than the first receptacle, two reagent access needles positioned and fixed within the first receptacle with each of the two reagent access needles being positioned to access the reagent container, and a working fluid access needle and a waste access needle positioned and fixed within the second receptacle with the working fluid access needle and the waste access needle being positioned to access the working fluid and waste container.
Patent MX-2020011256-A (MX)
Title: Construction system using prefabricated concrete elements.
Inventor: ZAMORA DÍAZ CÁNDIDO
IPC: E04C2/288
Filed: 2019-04-23
Abstract: The invention relates to a construction system using multi-layer prefabricated concrete elements, combining vertical elements (fig. 1) and horizontal elements. The vertical elements are formed by prefabricated panels containing the following layers: an external or facade layer (1); an insulating layer (2); a structural concrete layer (3); and internal finishing layer (6). The horizontal elements include a structural concrete layer.
Patent MX-2020013014-A (MX)
Title: N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors.
Inventor: CHEN JIANYONG
IPC: A61P35/00
Filed: 2019-01-31
Abstract: The present disclosure provides compounds having Formula I-A: and the pharmaceutically acceptable salts and solvates thereof, wherein A, X<sup>1 </sup>, X<sup>2</sup>, X<sup>3</sup> R<sup>1a</sup>, R<sup>1b</sup> E, and = are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I-A for use to treat a disease, disorder, or condition responsive to Bc1-2 protein inhibition such as cancer.
Patent MX-2021001239-A (MX)
Title: Aerosol generation.
Inventor: BENNING JOCELYN
IPC: A24B15/16
Filed: 2019-07-31
Abstract: Described herein is alaminat eaerosol generating material, wherein the material comprises an aerosol-forming layer attached to a carrier layer, wherein the aerosol- forming layer comprises an amorphous solid, and wherein the carrierlayer has a thickness from about 10Âµm to about 2.5mm.
Patent MX-2021001494-A (MX)
Title: Dkk1 antibodies and methods of use.
Inventor: LU HSIENG SEN
IPC: C07K16/22
Filed: 2013-04-26
Abstract: The present invention provides antibodies and immunologically functional fragments thereof that specifically bind DKK1 polypeptides. Methods for preparing such antibodies or fragments thereof as well as physiologically acceptable compositions containing the antibodies or fragments are also provided. Use of the antibodies and fragments to treat various diseases are also disclosed.
Patent MX-2021002551-A (MX)
Title: Crystalline forms of a phosphoinositide 3-kinase (pi3k) inhibitor.
Inventor: BURNS DAVID M
IPC: A61K31/435
Filed: 2019-09-04
Abstract: The present invention relates to salts and crystalline forms of 2-(3-(8-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl)-4- methylphenyl)-3,3,3-trifluoro-2-hydroxypropanamide, crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-methyl-5-(1,1,1-trifl uoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carbox amide, and crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-d3)-5-(1,1,1- trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-c arboxamide, which are PI3K inhibitors useful in the treatment of cancer and other diseases.
Patent MX-2021003090-A (MX)
Title: Erbumine salt of treprostinil.
Inventor: REMICK DAVID MICHAEL
IPC: C07C51/43
Filed: 2019-09-11
Abstract: A novel salt of treprostinil and methods of its preparation and use are disclosed.
Patent MX-2021003783-A (MX)
Title: Anti-malaria compositions and methods.
Inventor: POWELL THOMAS J
IPC: A61K9/50
Filed: 2019-10-01
Abstract: Multilayer films comprise polypeptide epitopes from Plasmodium falciparum, specifically a circumsporozoite CIS43 epitope and one or more of circumsporozoite T1, B or T* epitope. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes one or more polypeptide epitopes from a Plasmodium protozoan.
Patent MX-2021005456-A (MX)
Title: Capsule for food or beverage preparation comprising an oversized membrane.
Inventor: DOGAN NIHAN
IPC: B65D85/804
Filed: 2019-11-19
Abstract: The invention relates to a capsule (1) for food or beverage preparation, the capsule (1) comprising a hollow body (2) adapted to be punctured for fluid injection inside the capsule (1), a chamber (10) formed inside the body (2) and containing an ingredient, a membrane (9) covering an opening formed in a bottom end of the chamber (10), an edge of the membrane being fastened to a rim (12) surrounding the opening by fastening means which forms a seal between the body (2) and the membrane (9), and opening means disposed outside the chamber (10) in the vicinity of the membrane (9) configured to open the membrane when it is pressed against said opening means under an opening pressure. The part of the membrane (9) which is surrounded by the seal has a developed surface area comprised between 110% and 140% of the area of a flat surface surrounded by said seal.
Patent MX-2021005837-A (MX)
Title: Pivot hinge.
Inventor: MITCHELL BRETT
IPC: E05D5/00
Filed: 2021-05-18
Abstract: A pivot hinge includes a spring housing with a central tube, a spring assembly, an upper mounting plate, and a lower mounting plate. The bottom end includes a knurled outer surface. A stop cam is positioned about the knurled outer surface and has an inner surface that conform to the knurled outer surface so that it may be positioned in a plurality of rotatable positions relative to the central tube. The stop cam also has an exterior surface which includes a detent. The different rotational positions of the stop cam upon the knurled outer surface changes the relative position of the detent in relationship to the central tube. A cam follower assembly is coupled to the lower mounting plate and has a cam follower plate with a cam follower that rides upon the stop cam and engages the detent recess to hold the door in an open position.
Patent MX-2021006882-A (MX)
Title: Aerosol generating article with light hollow segment.
Inventor: UTHURRY JÉRÔME
IPC: A24D1/02
Filed: 2019-12-20
Abstract: An aerosol-generating article (10) for producing an inhalable aerosol when heated comprises: a rod of aerosol-generating substrate (12); and a hollow tubular segment (16) downstream of and in longitudinal alignment with the rod (12). The hollow tube segment (16) defines a cavity extending all the way from an upstream end of the hollow tubular segment (16) to a downstream end of the hollow tubular segment (16). The article (10) comprises a ventilation zone (26) at a location along the hollow tubular segment. The hollow tubular segment has a length of less than about 25 millimetres. A ratio between a weight of the hollow tubular segment and a volume of the cavity defined by the hollow tubular segment is less than 1 milligram/cubic millimetres. The rod (12) of aerosol-generating substrate comprises at least an aerosol former, the rod (12) having an aerosol former content of at least about 10 percent on a dry weight basis.
Patent MX-2021007891-A (MX)
Title: Adhesive composition and methods of forming the same.
Inventor: GORDON JAMES N
IPC: C09J133/04
Filed: 2019-12-19
Abstract: An adhesive composition may include at least about 2 wt.% and not greater than 49 wt.% of a (meth)acrylic based polymeric component A for a total weight of the adhesive composition, at least about 51 wt.% of a (meth)acrylic based polymeric component B for a total weight of the adhesive composition, and at least about 0.1 wt.% and not greater than about 30 wt.% of a tackifier component for a total weight of the adhesive composition. The (meth)acrylic based polymeric component A may have a glass transition temperature (Tg) of at least about 40 Â°C. The (meth)acrylic based polymeric component B may have a glass transition temperature (Tg) of not greater than about 20 Â°C. Further, the (meth)acrylic based polymeric component B may be acid-free.
Patent MX-2021010933-A (MX)
Title: Nucleic acid sequence for detecting maize plant dbn9501 and detection method therefor.
Inventor: LI FENG
IPC: C12Q1/6895
Filed: 2020-02-21
Abstract: Provided are a nucleic acid sequence for detecting a genetically modified maize event DBN9501 and a detection method therefor, the nucleic acid sequence comprising SEQ ID NO: 1 or a complementary sequence thereof, or SEQ ID NO: 2 or a complementary sequence thereof. Also provided are a method for preparing a maize plant that is resistant to insects and/or tolerant to glufosinate-ammonium herbicide, a method for cultivating a maize plant that is resistant to insects and/or tolerant to glufosinate-ammonium herbicide, and a method for protecting a maize plant from damage caused by herbicides or for controlling weeds in the field in which a maize plant is grown, the genome of the maize plant comprising nucleic acid sequences shown in SEQ ID NO: 1 and/or SEQ ID NO:2, nucleic acid sequences shown in SEQ ID NO:3 and/or SEQ ID NO:4 or a nucleic acid sequence shown in SEQ ID NO:5.
Patent MX-2021011325-A (MX)
Title: Methods and compositions for editing nucleotide sequences.
Inventor: LIU DAVID R
IPC: C12N15/10
Filed: 2020-03-19
Abstract: The present disclosure provides compositions and methods for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The nucleotide change can include a single- nucleotide change (e.g., any transition or any transversion), an insertion of one or more nucleotides, or a deletion of one or more nucleotides. More in particular, the disclosure provides fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap, which is homologous to a strand of the targeted endogenous DNA sequence to be edited, but which contains the desired one or more nucleotide changes and which, following synthesis by the polymerase (e.g., reverse transcriptase), becomes incoporated into the target DNA molecule. Also disclosed herein are various methods that leverage prime editing, including treating trinucleotide repeat contraction diseases, installing targeted peptide tags, treating prion disease through the intallation of protection mutations, manipulating RNA-encoding genes for the installation of RNA tags for controlling the function and expression of RNA, using prime editing to construct sophisticated gene libraries, using prime editing to insert immunoepitopes into proteins, use of prime editing to insert inducible dimerization domains into protein targets, and delivery methods, among others.
Patent MX-2021012813-A (MX)
Title: Slow-release cytokine conjugates.
Inventor: SANTI DANIEL V
IPC: A61K47/60
Filed: 2020-04-24
Abstract: This disclosure generally relates to releasable cytokine conjugates and methods of using the same.
Patent MX-2021013419-A (MX)
Title: Low temperature vials and vial assemblies.
Inventor: ASSELTA ROGER P
IPC: A61J1/06
Filed: 2020-05-01
Abstract: Vials and vial assemblies for storing a medicament in low temperature environments are provided. In one exemplary embodiment, a vial is provided that includes a base portion and a finish portion. The finish portion has an outer surface and an inner surface, in which the inner surface defines a channel that is configured to receive a first portion of a deformable sealing member. The finish portion on the outer surface thereof includes a surface feature that is configured to engage with a second portion of the deformable sealing member. The surface feature is configured to remain engaged with the second portion of the deformable sealing member when the deformable sealing member contracts from a first configuration to a second configuration, thereby maintaining a seal between the finish portion and the deformable sealing member.
Patent MX-2021014037-A (MX)
Title: Self-cleaning aortic blood filter.
Inventor: KEEBLE DUNCAN
IPC: A61F2/01
Filed: 2020-05-18
Abstract: A blood filter having a support structure and a filter structure. Various embodiments of the filtering assemblies may be utilized as a temporary implant or a permanent implant. The support structure, which serves as an anchor for the blood filter may define a larger porosity. The filter structure may define a smaller porosity, the smaller pores of which prevent emboli from passing therethrough. The support and filter structures may be made separately and assembled. In some embodiments, the filter structure actively slides on the support structure to accommodate the collapsing and deployment of the filter assembly. In some embodiments, a polymer film is selectively applied to the filter structure to provide a more uniform porosity over an outer bend radius of the filter structure. In some embodiments, the filter assembly is shaped to conform to the contours of the aortic arch while enabling self-cleaning of the filter structure.
Patent MX-2021014080-A (MX)
Title: Cap and container for carbonated drinks.
Inventor: MACRELLINO DIEGO
IPC: B65D47/04
Filed: 2020-05-15
Abstract: A cap and container reduce carbonation loss in filling containers with carbonated beverages. The cap has a splashguard with a circular bottom connected by a conical transition to a smaller diameter, cylindrical ring portion. A circular dispersing disk is above the transition and connected to the cap, with a small radial gap between the disks periphery and the splashguard. A fluid seal is interposed between the ring portion and an open top of the container. The dispersing disk directs a fluid stream outward against the splashguard where the fluid passes through the radial gap around the disk and flows downward in a laminar flow over the conical transition and ring portions. A lip on the bottom of the ring portion extends outward and downward to conduct the laminar flow onto the container sidewall, which is inclined at less than five degrees to maintain laminar flow along the sidewall when filling.
Patent MX-2021014373-A (MX)
Title: Trisazo compounds for ink-jet printing.
Inventor: LIMPER DOMINIK
IPC: C09B33/22
Filed: 2020-05-29
Abstract: Trisazo compounds of formula (I), with the proviso that R<sup>1</sup> represents SO<sub>3</sub> M if R<sup>2</sup> represents hydrogen. These trisazo compounds are extremely well suited to dyeing and printing natural and synthetic materials, and in particular to using as recording liquid media for ink-jet printing.
Patent MX-2021015057-A (MX)
Title: Anti-talen antibodies and uses thereof.
Inventor: SASU BARBRA JOHNSON
IPC: C07K16/18
Filed: 2020-06-12
Abstract: The present disclosure provides, among other things, antibodies for detecting TALENs and/or FokI nucleases in a sample and methods of using the same.
Patent MX-2022003094-A (MX)
Title: Alternative methods for whitening tobacco.
Inventor: ZAWADZKI MICHAEL ANDREW
IPC: A24B13/00
Filed: 2020-09-09
Abstract: The present disclosure provides a method of preparing whitened tobacco composition including chemically pulping a tobacco material to form a tobacco pulp, extracting the tobacco pulp with an extraction solution, treating the tobacco pulp with a solution comprising an oxidizing agent for a time and at a temperature sufficient to lighten the color of the tobacco pulp to give a whitened tobacco pulp, and drying the whitened tobacco pulp to provide the whitened tobacco composition. Alternative bleaching processes and treatment methods effective for preparing whitened tobacco compositions are also provided herein.
Patent MX-2022003430-A (MX)
Title: Secure voting system over the internet.
IPC: G07C13/00
Filed: 2022-03-22
Abstract: The present invention is about a Secure Voting System over the internet where a Voting User request to vote over the internet. The request is handled by an Internet Voting Regulator Agency in charge of managing the internet voting by interacting with the Voting User, and using an external independent web server Rhythm Certification Agency to authenticate the voting user, and an Official Voting Agency to officially supervise and record the voting process. The Voting User will be authenticated by means of his/her typing rhythm recorded at computer device of the Voting User, and the analysis of the typing rhythm recorded results with the previous typing rhythm statistics stored at the Rhythm Certification Agency. The Internet Voting Regulator Agency will send the Voting User a text to be typed and record the typing rhythm of such text by the voting User, the results of the typing rhythm will be sent to be analyzed by the external independent web server Rhythm Certification Agency which will authenticate the voting user. Only voting users registered and authenticated at the Rhythm Certification Agency will be permitted to vote over the internet..
Patent MX-2022004566-A (MX)
Title: Agonist of tacr2.
Inventor: GERHART-HINES ZACHARY
IPC: A61K38/08
Filed: 2019-10-17
Abstract: The present disclosure relates to agonists of Tacr2, such as peptides agonist of Tacr2 and methods of using the same for treatment of insulin resistance, obesity and/or diabetes. The disclosure also relates to use of said agonists of Tacr2 for enhancement of energy consumption in an individual.
Patent MX-2022004982-A (MX)
Title: Knitted socks.
Inventor: CERA JUAN
IPC: A41B11/00
Filed: 2020-11-03
Abstract: Knitted socks or other garments or portions thereof and methods for producing knitted socks or other garments or portions thereof which stay in place when worn with less or no spandex or rubber fiber in the sock or other garment or portion thereof are provided.