baber/WOPTO huggingface dataset:
Patent CY-1114500-T1 (CY)
Title: Γεφυρωμενα παραγωγα σπειρο[2.4]επτανιου ως αγωνιστες υποδοχεων alx kai/ή fprl2
Inventor: BUR DANIEL
IPC: C07D235/14
Filed: 2013-10-16
Abstract: Η παρούσα εφεύρεση αναφέρεται σε γεφυρωμένα παράγωγα σπείρο[2.4] επτανίου του χημικού τύπου (Ι), όπου τα W, Υ, Ζ, R1 και R2 είναι όπως ορίστηκαν στη περιγραφή, στη παρασκευή τους και στη χρήση τους ως φαρμακευτικώς δραστικές ενώσεις και συγκεκριμένα στη χρήση τους ως αγωνιστές υποδοχέων ΑLΧ και/ή FΡRL2.
Patent CY-1115035-T1 (CY)
Title: Μεθοδος για την παρασκευη ενεργοποιημενων εστερων
Inventor: BIGOT ANTONY
IPC: C07D213/71
Filed: 2014-04-22
Abstract: Η εφεύρεση σχετίζεται με μία μέθοδο για την παρασκευή ενεργοποιημένων εστέρων με τον τύπο (I), στον οποίο το R είναι μία ομάδα (C1-C6)αλκυλίου, αρυλίου, ετεροαρυλίου, κυκλοαλκυλίου ή ετεροκυκλοαλκυλίου και το Alk είναι μία ομάδα (C1-C6)αλκυλενίου, η εν λόγω μέθοδος συνίσταται στην αντίδραση του άλατος της δικυκλοεξυλαμίνης Ρ1 και του ανθρακικού διηλεκτριμιδυλίου (DSC) μέσα σε ένα διαλύτη μέσα στον οποίο το άλας της δικυκλοεξυλαμίνης του Ν-υδροξυηλεκτριμιδίου Ρ2 καθιζάνει. Η εφεύρεση σχετίζεται επίσης με προϊόντα με τον τύπο Ρ1.
Patent HR-P20120182-T1 (HR)
Inventor: DENG SHIXIAN
IPC: C07D281/10
Filed: 2012-02-24
Abstract: Postupak za pripremu 2,3,4,5-tetrahidro[1,4]benzotiazepina formule: koji uključuje reakciju [2-(acilaminoetil)tio]arena formules aldehidom formule R4CHO ili njegovim multimerom, te s kiselinom, naznačen time, da: Ar je monociklički, biciklički ili triciklički arilni ili heteroarilni prstenski sustav; R1, R2 i R4 svaki za sebe predstavlja H, (C1-C20)ugljikovodik, (C1-C6)alkil, cikloalkil, aril, heterociklil, heteroaril, (C1-C6)alkil-aril, (C1-C6)alkil-cikloalkil, (C1-C6)alkil-heterociklil ili (C1-C6)alkil-heteroaril, a svaka od sljedećih skupina: aril, cikloalkil, heterociklil i heteroaril po izboru je supstituirana s jednim do tri supstituenta neovisno odabranih iz skupine koju čine: halogen, alkil, alkoksil, nitro, cijano i haloalkil; R3 je (C1-C10)acil; P(O)R8R9, C(=O)-R10, C(=S)-R11, S(=O)2R12, (CH2)mR13, zaštitna skupina za dušik, OH, (C1-C6)alkil, cikloalkil, aril, heterociklil, heteroaril, (C1-C6)alkil-aril, (C1-C6)alkil- cikloalkil, (C1-C6)alkilheterociklil ili (C1-C6)alkilheteroaril, a svaka od sljedećih skupina aril, cikloalkil, heterociklil i heteroaril po izboru supstituirana s jednim do tri supstituenta neovisno odabranih iz skupine koju čine: halogen, alkil, alkoksil, nitro, cijano i haloalkil; ili, zajedno, R2 i R3 tvore okso-supstituirani heterocikl koji sadrži dušik; R5 je u svakom od svojih pojavljivana neovisno odabran između sljedećeg: H, (C1-C20) ugljikovodik, (C1-C6)alkil, cikloalkil, aril, heterociklil, heteroaril, (C1-C6)alkil-aril, (C1-C6)alkil- cikloalkil, (C1-C6)alkil-heterociklil, (C1-C6)alkil-heteroaril, halogen, acil, SO3, -OR6, -SR6, - NR6aR6b, -N(R6)C(=O)OR7, N(R6)C(=O)R7, -C(=O)NR6aR6b, -C(=O) OR6, -C(=O)R6, -OC(=O)R6, - NO2, -CN, -(C1-C6)haloalkil, -O-(C1-C6)haloalkil, -N3 ili -P(O)R8R9, a svaka od sljedećih skupina: aril, cikloalkil, heterociklil i heteroaril po izboru je supstituirana s jednim do tri supstituenta neovisno odabranih iz skupine koju čine: halogen, alkil, alkoksil, nitro, cijano i haloalkil; R10 i R11 svaki za sebe predstavlja H, -OR14, -NR6aR6b, NHNHR15, NHOH, CONH2NHR15, CO2R15, CONR15, halogen, alkoksi, ariloksi, aliloksi, benziloksi, supstituirani benziloksi, fluoroenilmetoksi, adamantiloksi, (C1-C20)ugljikovodik, (C1-C6)alkil, cikloalkil, aril, heterociklil, heteroaril, (C1-C6)alkil-aril, (C1-C6)alkil-cikloalkil, (C1-C6)alkilheterociklil ili (C1-C6)alkil-heteroaril, a svaka od sljedećih skupina: aril, cikloalkil, heterociklil i heteroaril po izboru je supstituirana s jednim do tri supstituenta neovisno odabranih iz skupine koju čine: halogen, alkil, alkoksil, nitro, cijano i haloalkil; R6, R6a, R6b, R7, R8, R9, R12, R14, R15, R16 i R17 svaki za sebe predstavlja u svakom od svojih pojavljivanja H, -OR15, -NR15R16, NHNHR16, NHOH, (C1-C20)ugljikovodik, (C1-C6)alkil, cikloalkil, aril, heterociklil, heteroaril, (C1-C6)alkil-aril, (C1-C6)alkil-cikloalkil, (C1-C6)alkil-heterociklil ili (C1- C6)alkil-heteroaril, a svaka od sljedećih skupina: aril, cikloalkil, heterociklil i heteroaril po izboru je sup
Patent SI-1572407-T1 (SI)
Title: Tangential cutting insert and milling cutter
Inventor: SATRAN AMIR
IPC: B23C5/22
Filed: 2003-09-22
Abstract: A tangential milling cutting insert (10) having two identical opposing end surfaces (12) with two identical opposing major side surfaces (18) of a generally parallelogrammatic shape and two identical opposing minor side surfaces (16) extending between them. Each end surface (12) has a peripheral edge (40) containing cutting edges (52) and four corners of which two diagonally opposed corners are lowered (24) and the other two are raised (26). Each end surface is provided with an abutment (28) member having an abutment surface. In each cross section of the cutting insert taken in a plane parallel to a minor plane of the cutting insert, the abutment surface (30) is closer to the median plane than a respective leading section of a major cutting edge (54).
Patent SI-1527100-T1 (SI)
Title: Human monoclonal antibodies to interleukin-5 and methods and compositions comprising same
Inventor: GREENFEDER SCOTT
IPC: A61K39/00
Filed: 2003-03-27
Abstract: The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to interleukin 5 (IL-5), which is preferably human IL-5. The invention also relates to human anti-IL-5 antibodies, including chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulin molecules derived from anti-IL-5 antibodies and nucleic acid molecules encoding such molecules. The present invention also relates to methods of making anti-IL-5 antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-IL-5 antibodies. The invention also relates to gene therapy methods and transgenic animals comprising nucleic acid molecules of the present invention.
Patent SI-3438116-T1 (SI)
Title: Labelled nucleotides
Inventor: MILTON JOHN
IPC: G01N33/00
Filed: 2003-08-22
Abstract: The invention provides a nucleotide or nucleoside having a 3'-azidomethyl group and a base attached to a detectable label via a linker.
Patent SI-1877426-T1 (SI)
Title: Method for preventing or treating m tuberculosis infection
Inventor: COLER RHEA
IPC: A61K39/00
Filed: 2006-04-27
Abstract: The present invention is directed to methods of preventing reactivation of active and latent  M. tuberculosis  infections by administering a pharmaceutical composition comprising a nucleic acid encoding a Mtb72f fusion protein, or a Mtb72f fusion protein or an immunogenic fragment thereof, for example together with an adjuvant. The Mtb72f nucleic acid or fusion protein can be administered with one or more chemotherapeutic agents effective against a  M. tuberculosis  infection. The methods also provide for shortening the time course of a chemotherapeutic regimen against a  M. tuberculosis  infection.
Patent TR-200402212-T1 (TR)
Title: Titreşim önleyici sürtünmeli amortisör
Inventor: KANIOEZ ADIL
IPC: F16F7/09
Filed: 2002-03-04
Abstract: Bu buluş, özellikle dönme hareketli yıkama tamburlu çamaşır makinelerinde kullanılan bir titreşim önleyici sürtünmeli amortisör ile ilgilidir.
Patent TR-200903588-T1 (TR)
Title: Kızılötesi ısı transferli ışıklık borusu
Inventor: JASTER PAUL
IPC: E04B7/18
Filed: 2007-11-02
Abstract: Bir ışıklık baca substratı (42, 102, 202, 302), iç yüzeyinin üzerinde bir film veya kaplamaya (40, 52, 204, 304) sahiptir, bu film veya kaplama görünür ışığı yansıtırken, kızılötesi ışığı boru substratına iletir, söz konusu boru substratı saten siyahı ve/veya diğer kir emici bir iç yüzeye ve ısıyı borudan iletmek üzere anotlaştırılmış veya yüksek yayım kapasiteli bir diğer dış yüzeye sahiptir ve böylece, ışık borudan aşağı iletilirken, ısı iletiminin borunun içerisinden yönlendirilmesi sağlanarak, aydınlanan boşluğun ısınması asgari düzeye çekilmiş olur. Veya ısının borunun içerisinden yukarı doğru ilerletilmesi ve boruyu örten bir berrak plastik kubbenin (21, 114, 212) içerisinden dışarı çıkması sağlanır.
Patent DE-3486106-T2 (DE)
Inventor: SHAW HERBERT JOHN
IPC: H01S3/05
Filed: 1984-09-20
Granted: 1993-09-30
Abstract: A side pumped, fiber optic amplifier comprises an optical fiber (12), having a first refractive index, formed of a laser material, such as Nd:YAG. A jacket (14), which surrounds the optical fiber (12), has a second refractive index, lower than the first refractive index. This jacket (14) is cone shaped and tapers from a large end (16) to a small end (18). High power laser diodes are mounted on the large end (16) to produce collimated pump light to pump the optical fiber material. The cone shaped jacket (14) focuses this pump light to an interaction region at the small end (18), where the jacket material is quite thin, e.g. on the same order of magnitude as the diameter of the optical fiber (12). The focused light is absorbed by the optical fiber (12) in this interaction region, and causes an electronic population inversion in the laser fiber material. A signal propagating through the optical fiber (12) stimulates spontaneous emission from the optically excited laser material, thereby resulting in amplification of the signal.
Patent DE-3689254-T2 (DE)
Inventor: DEL SOLDATO PIERO
IPC: A61K31/485
Filed: 1986-09-24
Granted: 1994-03-17
Abstract: The object of the invention is a pharmaceutically acceptable composition suitable to achieve a systemic therapeutical response due to its antitussis action in warm-blooded animals, characterized in that it contains, per dosage unit: (I) an amount therapeutically efficacious by systemic way due to the antitussis action of salified dextrorphan, and (II) a pharmaceutically non-toxic excipient acceptable for intranasal administering.
Patent DE-3779983-T2 (DE)
Inventor: VOGEL JOHANNES ALBERTUS
IPC: B67D7/46
Filed: 1987-08-26
Granted: 1992-12-10
Abstract: Acoustic signals are transmitted through the fluid flow of a fuel delivery pump to a tank to be filled. From reflection signals the fluid level in the tank is detected and a timely disconnection of the pump can be effected in order to prevent fuel losses.
Patent DE-3781323-T2 (DE)
Inventor: LANKOW RICHARD K
IPC: G01N33/543
Filed: 1987-05-19
Granted: 1992-12-17
Abstract: A method and a kit for testing a plant for a suspected antigen. A sample of the plant is taken and rubbed between first and second pads to extract sap from the sample and to collect the sap on the first pad. The sap is transferred to a liquid solution, and that solution is tested for the suspected antigen. This may be done by contacting the solution with a tag antibody and with a carrier having a capture antibody so that a tag antibody-antigen-capture antibody complex forms on the carrier if the suspected antigen is in the liquid solution. The carrier is then tested for the tag antibody. The kit preferably includes the first and second pads, the carrier, containers to hold the liquid solution and the tag antibody, and a device or reagent to test the carrier for the tag antibody.
Patent DE-3852973-T2 (DE)
Inventor: AUSTIN PAUL EDWIN
IPC: C09K23/54
Filed: 1988-07-01
Granted: 1995-05-24
Abstract: An improved process is provided for the preparation of siloxane-oxyalkylene block copolymer surfactant compositions which utilized a hydrosilation reaction with high boiling point polar polyols as the reaction solvent. The reaction solvent need not be removed from the block copolymer, particularly when the block copolymer is used as a surfactant for polyurethane foam formulations. Dipropylene glycol is the preferred polar solvent and when used in the preparation of the surfactants need not be removed when the surfactants are employed in the preparation of urethane foams.
Patent DE-3856068-T2 (DE)
Inventor: HENERY VERN ALLAN
IPC: C23C16/40
Filed: 1988-09-22
Granted: 1998-05-20
Abstract: A method and apparatus are disclosed for producing a low emissivity metal oxide film on a glass surface within a nonoxidizing atmosphere inside a float bath.
Patent DE-3884828-T2 (DE)
Inventor: FORTH LESLIE
IPC: H04L25/49
Filed: 1988-02-24
Granted: 1994-04-21
Abstract: A digital filter receive circuit for use with a StarLAN coded data transceiver includes three D-type flip-flops (U1, U2, U7) and four NAND logic gates (U3, U4, U5, U6). The digital receive line filter circuit is capable of being implemented as part of a single monolithic integrated circuit containing the transceiver, thereby producing a miniaturized and compact structure.
Patent DE-3885474-T2 (DE)
Inventor: VILLI PIERGIORGIO
IPC: H02G3/04
Filed: 1988-02-08
Granted: 1994-03-03
Abstract: The present invention relates to a modular element system for making raceways for electrical cables and the like, comprising a channel shaped body, of U-shaped cross section which can be closed by a cover member. On the side walls of the channel body there are provided coupling recesses for housing both jointing section members,adapted for allowing for a plurality of raceway bodies to be arranged in an adjoining condition, and bracket members for supporting the channel bodies.
Patent DE-3888566-T2 (DE)
Inventor: MARBROW RICHARD ANTHONY
IPC: B41M5/40
Filed: 1988-04-12
Granted: 1994-07-21
Abstract: A thermal transfer printing (TTP) receiver sheet has a receiving layer comprising a crystalline synthetic thermoplastics polymer.
Patent TR-199900289-T2 (TR)
Inventor: MAGGI LAURETTA
IPC: A61K31/505
Filed: 1997-08-22
Abstract: Bulus; a)katman agirliginin %5-90'ini, tercihen %10-85'ini teskil eden hidrofilik polimerlerden olusan bir karisimin veya bir granülün sikistirilmasi ile üretilen, sulandirilmis biyolojik sivilarla temas ettiginde dikkat çekecek kadar ve hizla kabarma özelligine sahip olan bir birinci katmandan(1); b)ilaca uygun sikistirilabilirlik özelliklerini vermek ve belirli bir zaman periyodu içerisinde alfuzosin hidroklorürün salinimina imkan vermek üzere hidrofilik polimerlerle ve diger yardimci maddelerle formüle edilen, içerisinde alfuzosin hidroklorür tasinan, birinci katmana bitisik olan bir ikinci katmandan(2); c)ve aktif maddenin geçisine karsi yüksek ölçüde geçirmez olan, özellikle peltelesen ve/veya kabaran ve daha sonra istege bagli olarak ayrisabilen hidrofilik polimerlerden olusan ve katman 2'den alfuzosin hidroklorür salinimini modifike eden bir bariyer fonksiyonuna sahip olan, sikistirmayla elde edilen ve katman 2'ye uygulanan, istege bagli olan bir üçüncü katmandan...DEVAMI VAR^
Patent AT-E544916-T2 (AT)
Inventor: GRANDI RUGGERO
Filed: 2009-02-18
Granted: 2012-02-15
Abstract: A multipurpose beam for side-by-side panel false ceiling constructions includes a bearing profile with a pair of side was joined together by a substantially horizontal wall and having a bottom opening, at least one functional element with an anchoring portion designed to be received in the compartment, coupling means for connecting together the profile and the anchoring portion, and support means associated with the profile for supporting at least one panel of a false ceiling construction. The anchoring portion of the functional element is designed to hold the functional element integrated in the profile and entirely contained in the compartment. The support means extend from the side walls to hold the panels substantially flush with the longitudinal edges of the opening. A false ceiling structure and a modular system for customized design of a false ceiling that includes the beam are also provided.
Patent DE-60005708-T2 (DE)
Inventor: OJAVUO ASKO
IPC: B25B27/06
Filed: 2000-12-01
Granted: 2004-08-19
Abstract: A device for decoupling an inner part and an outer part of a constant velocity joint from each other has a fastening element for gripping the inner part, an annular part placed in the end of the outer part of the joint and a nut that fits to the thread in the end of the outer part, which nut is wider than the hole in the annular part and the parts can be decoupled in a simple and safe way and without breaking the parts.
Patent DE-60015397-T2 (DE)
Inventor: PAINTER DONALD
IPC: B01J20/04
Filed: 2000-03-02
Granted: 2005-10-13
Abstract: The present invention relates to a method and an apparatus for removing malodor from the air. Such methods and devices are useful for example for storing and preserving food in closed compartments such as refrigerators. The method of the present invention comprises the steps of positioning first filter member inside said confined space independent from the position of a second filter member and of removing malodor molecules from the air of said confined space by adsorbing said molecules onto the surfaces of said first filter member and onto the surfaces of said second filter member. The apparatus of the present invention is characterized in that a first filter member is attachable to an air moving member and a second filter element is attachable to the air moving member.
Patent DE-60015559-T2 (DE)
Inventor: YEH EDWARD T H
IPC: C12Q1/37
Filed: 2000-07-31
Granted: 2005-10-27
Abstract: The invention relates to a novel protease, called SENP1, which is active against sentrin-modified proteins in vivo. The invention more specifically relates to the genomic and amino acid sequences for SENP1, compositions related to and based on these sequences, and methods of using these sequences and compositions.
Patent DE-60017618-T2 (DE)
Inventor: ANDRE JEAN
IPC: F24J2/52
Filed: 2000-02-18
Granted: 2006-03-23
Abstract: The panel mounting for a solar collector has a first set of glazing supports cooperating with framing (30) to grip the opposed edges of the panes (32). Each pane support flange (28) has a foot (66) to clip a corresponding clip (78) on the framing to form a connection without play to lock the panels between the joints.
Patent DE-60017749-T2 (DE)
Inventor: CSOEREGI ELISABETH
IPC: C12Q1/00
Filed: 2000-07-06
Granted: 2005-07-07
Abstract: The present invention relates to a biosensor for the detection and/or the determination of freshness biomarkers, such as biogenic amines (preferably histamine) in food and beverage, comprising an electrode and a mono-enzyme system, such as an amine oxidase, or a bi-enzyme system of an amine oxidase and a peroxidase. The enzymes are optionally crosslinked into an osmium based redox polymer.
Patent DE-60021602-T2 (DE)
Inventor: CRANA RENATO
IPC: B29C48/07
Filed: 2000-11-03
Granted: 2006-05-24
Abstract: The method is intended for the production of expanded polyolefin materials, having a coefficient of thermal conductivity below 40 mW/ DEG K*m and a density below 50 kg/m<3>, by the extrusion of a polymeric material with the addition of a physical expansion agent. The extrusion is carried out in a twin-screw extruder with co-rotating, interpenetrating screws (12), with a ratio between axial separation (I) and diameter (D) of between 0.7 and 0.8 and a length/diameter ratio (L/D) between 22 and 30, and in which the said screws (12) have a plurality of mixing areas (back mixing) (18a-c) and a plurality of alternating pumping areas (16a-d) with a length ratio between mixing areas (18a-c) and pumping areas (16a-d) of between 65% and 75%. During extrusion, the screws are rotated at less than 50 rpm.
Patent DE-60030903-T2 (DE)
Inventor: FLECK UTE
IPC: B01D11/00
Filed: 2000-01-20
Granted: 2007-04-05
Abstract: The invention relates to a process for preparing a highly loaded adsorbent, which process comprises the steps of   a) extracting an oil from an oil crude product by means of supercritical fluid extraction thus, obtaining a loaded supercritical fluid (SCF); b) expanding the loaded SCF of step a) followed by heating to obtain a liquid phase and a in-loading reduced SCF phase; c) optionally decreasing the pressure and/ or raising the temperature of the SCF phase of step b) to conditions of adsorption; d) introducing the SCF of step b) or step c) into a fixed bed adsorber to obtain an adsorbent loaded with the purified oil and pure SCF; e) feeding the liquid phase of step b) as a reflux to the extraction device of step a) ; f) compressing and tempering the pure SCF of step d) to extraction conditions;   g) recycling the pure SCF to the extraction device of step a).   The invention further comprises a process for purifying an oil from an oil crude product by desorbing the adsorbed oil. The invention further comprises 16 A process for purifying an oil, optionally combined with a process for preparing a highly loaded adsorbent, which process comprises the steps of:   A) extracting a fraction containing the oil together with high volatile components from a crude synthetic or natural oil mixture by means of supercritical fluid extraction (SFE) thus, obtaining a loaded supercritical fluid (SCF) and a raffinate containing the low volatile components of the crude product; B) expanding the loaded SCF of step A) followed by heating to obtain a liquid phase containing the oil and high volatile components and an unloaded gas phase (step B-1) or to obtain an in-loading reduced SCF and a liquid phase (step B-2); C) optionally decreasing the pressure and/ or raising the temperature of the in-loading reduced SCF phase of step B-2) to conditions of adsorption; D) optionally introducing the in-loading reduced SCF of step B-2) or of step C) into a fixed bed adsorber to obtain an unloaded gas phase and an adsorbent loaded with oil; E) collecting the unloaded gas phase of step B-1) or of step D) in a vessel and controlling the content of the gas components; F) optionally feeding pure gas into the vessel of step E) to guarantee the same gas composition over the whole process time; G) feeding part of the liquid phase of step B-1) or all of the liquid phase of step B-2) at the same temperature and pressure of the column as a reflux to the extraction device of step A); H) pressurizing the gas phase of step E) or of step F) followed by cooling to separation conditions; I) recycling the SCF of step H to the extraction device of step A);   J) optionally feeding the liquid phase of step B-1) to a second extraction device; K) extracting a fraction of high volatile components from the extract of step B-1) by means of SFE thus obtaining a loaded SCF and the pure oil as raffinate; L) treating the reflux and the SCF as described in the steps B-1 - I); M) collecting the oil at the bottom of the column as a raffinate.
Patent DE-60031352-T2 (DE)
Inventor: KO YOUNG HOON
IPC: C08F36/04
Filed: 2000-07-07
Granted: 2007-05-24
Abstract: This invention relates to a method for the selective hydrogenation of the unsaturated double bonds in the conjugated diene units of a homopolymer or copolymer in the presence of a novel homogeneous organotitanium-based catalyst. Also, the process of this invention can demonstrate a high yield of hydrogenation and hydrogenation reproducibility using a novel catalyst, so prepared from a mixture consisting of a substituted or unsubstituted monocyclopentadienyl titanium compound expressed by the following formula 1 and lithium hydride derived from a reaction of both alkyl lithium and hydrogen in solution. In particular, this invention also relates to a novel method for the selective hydrogenation of unsaturated double bonds in the conjugated diene units of a conjugated diene polymer or copolymer, so prepared via the reaction between a conjugated diene monomer and vinyl-substituted aromatic monomer. <CHEM> wherein, R1, R2, R3, R4 and R5, which may be same or different, are selected from hydrogen atoms and alkyl groups of 1 SIMILAR 5 carbon atoms; X1, X2 and X3, which may be same or different, are selected from halogen atoms.