baber/WOPTO huggingface dataset:
Patent NZ-524029-A (NZ)
Title: 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine2,4-dione, L(+) tartrate salt or a solvate thereof
Inventor: CHOUDARY BERNADETTE MARIE
IPC: A61P3/08
Filed: 2001-08-03
Abstract: A pharmaceutical compound 5-[4-2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, L(+) tartrate salt or a solvate thereof, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine for the treatment and/or prophylaxis of diabetes mellitus and conditions associated with diabetes mellitus is disclosed.
Patent NZ-524075-A (NZ)
Title: Finishing of metal surfaces using grit blasting and related applications
Inventor: GIROLAMO MARIO
IPC: B24C7/00
Filed: 2001-08-10
Abstract: A process for finishing a metal surface 10 comprises subjecting the surface to successive grit blasting passes including: (a) a first series of successive blasting passes using an abrasive grit of a first diameter range applied with a blasting nozzle air pressure in a first range; (b) a second series of successive blasting passes using an abrasive grit of a second diameter range smaller than the first diameter range, applied with a blasting nozzle air pressure in a second range lower than the first range and (c) thereafter a third series of successive blasting passes using glass grit of a third diameter range smaller than the second diameter range, applied with a blasting nozzle air pressure in a third range lower than the first range. The abrasive grit can be metallic oxide grit or spherical glass beads. The first range of the blasting nozzle air pressure can be 50 to 70 psi and the second range and third range of the blasting nozzle air pressure can be 30 to 50 psi. The metal surface can be of a roller grade steel suitable for use for embossing rollers and suitable for subsequent finishing of extruded plastics sheet.
Patent NZ-526974-A (NZ)
Title: Induction of tolerance
Inventor: TURINI MARCO
IPC: A61K31/24
Filed: 2001-12-20
Abstract: Disclosed is the use of an antigenic food material or antigenic parts thereof, and at least one substance capable of increasing the activity of COX-2 (cyclo-oxygenase 2) in cells of the individual and/or increasing the level of IFN-y (interferon y) in the manufacture of a composition for inducing oral tolerance to the antigenic food material. Examples of the food material include milk, egg, soya, nuts, crustacean, fish, meat, sesame, whey, berries or apples.
Patent NZ-527931-A (NZ)
Title: Virucidal compositions
Inventor: KONOWALCHUK THOMAS W
IPC: A01N31/00
Filed: 2002-02-13
Abstract: A topical composition for inactivating an enveloped virus at a site of infection, consisting essentially of: a pharmaceutically acceptable carrier; a C1-C3 alcohol or a C2-C4 dial; and a sufficient amount of an acid to adjust the pH of the composition to 4.6 or less, wherein said acid is an organic acid.
Patent NZ-530460-A (NZ)
Title: Chimeric immunomodulatory compounds and methods of using the same
Inventor: FEARON KAREN L
IPC: C07H15/18
Filed: 2002-06-21
Abstract: A chimeric immunomodulatory compound (CIC) comprising two or more nucleic acid moieties and one or more non-nucleic acid spacer moieties, wherein at least one non-nucleic acid spacer moiety is covalently joined to two nucleic acid moieties, wherein said spacer is not a polypeptide, wherein at least one nucleic acid moiety comprises the sequence 5'-CG-3' and wherein said CIC has immunomodulatory activity.
Patent NZ-533056-A (NZ)
Title: Polycistronic expression of antibodies
Inventor: REFF MITCHELL
IPC: A61K47/48
Filed: 2002-11-18
Abstract: A Chinese Hamster Ovary (CHO) cell that is stably transfected with a polycistronic vector for expressing functional antibodies in eukaryotic host cells, which vector comprises a polycistronic transcription system comprising the following elements operably linked in the 5Æ to 3Æ orientation: (i) a promoter operable in a eukaryotic cell; (ii) a first cistron comprising a first DNA sequence comprising a 5Æ start codon, a nucleotide sequence encoding an antibody light chain which optionally comprises at its 5Æ terminus a signal peptide coding sequence operable in eukaryotic cells, and a 3Æ terminal stop codon, wherein said first DNA sequence does not comprise a poly A sequence at its 3Æ end; (iii) an internal ribosome entry site (IRES) obtained from a member selected from the group consisting of a cardiovirus, a herpes virus and a poliovirus; (iv) at least an additional cistron comprising a second DNA sequence comprising a 5Æ start codon, a nucleotide sequence encoding an antibody heavy chain, a 3Æ terminal stop codon, and a poly A sequence at its 3Æ terminus; wherein the IRES is operably linked to the 5Æ end of the additional cistron with no intervening regulatory elements.
Patent NZ-533951-A (NZ)
Title: Distributed authorisation system
Inventor: VOSS MICHAEL ELIOT
Filed: 2004-07-07
Abstract: A distributed authorisation system is disclosed. The system includes an authorisation site from which a licensed applicator of security seals, markings and labels (herein "security seals") can obtain, upon sending a request via a server, a unique number or series of unique numbers allocated by the authorisation site, where the number or series of numbers are for use with security seals to be issued by the licensed applicator. A licensing authority is able to audit, via the server, the activities of the authorisation site and licensed applicator, in connection with the issuing and use of the unique numbers.
Patent NZ-543221-A (NZ)
Title: Anti-rotation foot for strainer post
Inventor: SMITH MICHAEL ALEXANDER
Filed: 2005-10-27
Abstract: A fence post footing comprising a steel plate having a flat base and a vertical panel folded along one side of the base to form an "L" profile footing, a bendable tab formed in the side of the base opposite the panel by slots in the base, and apertures provided in each of the vertical panel, base and tab to facilitate nailing of the footing to the flat bottom and sides of a post. The foot further comprises a steel tongue pressed from the flat steel base of the foot which protrudes from the base of the vertical panel at an angle of 90 degrees. In use a 360 degree engagement with the retaining material in which the post is embedded is provided. (62) Addition to 530862
Patent NZ-546829-A (NZ)
Title: Method for controlling fungi and mites in textile substrates
Inventor: MCCLELLAN WILLIAM
IPC: A01N43/54
Filed: 2004-11-22
Abstract: A method of controlling the growth of fungi in a carpet made from a textile material such as polyacrylonitrile, polyamide and polyester is disclosed, wherein the method comprises applying to the textile material a fungicidally effective amount of a fungicidal compound, wherein the fungicidal compound is selected from the group consisting of strobilurin fungicides, pyrrole fungicides, anilide fungicides, conazole fungicides, thiazole fungicides and pyrimidine fungicides. Particularly preferred fungicidal compounds are strobilurin fungicides such as azoxystrobin and pyrrole fungicides such as fludioxonil.
Patent NZ-550532-A (NZ)
Title: An improved window stay mountable between a window sash and window frame
Inventor: MCKINNEY PAUL GARY
Filed: 2006-10-12
Abstract: A window stay comprising an arm (1), with side rail (4), which slides through an enclosed housing (6) which is pivotally fixed to a base (7) which is mounted to the immovable part of the window frame. A recessed groove (2) along the bottom of the arm (1) features a multiple of semicircular recesses (3). A turn handle (5) is pivotally fixed to the enclosed housing. The other end of the arm is attached to a bracket (14) which in turn is mounted to the movable part of the window frame. The arm also features a bump stop (15) to prevent it being withdrawn completely from housing.
Patent NZ-552537-A (NZ)
Title: A system and method for providing a sample of a product to shoppers
Inventor: MEBRUER ROBERT
Filed: 2005-07-08
Abstract: A system and method for providing a sample of a product to shoppers is disclosed. An input device such as a card reader (115) is provided for reading a shopper's card to identify the shopper and a targeted list (111) of promotions for that shopper can be generated by a printer (116). Sample products which are to be received by the customer, together with the promotional product list, is produced by a processor (P1) from information provided by a database storing the characteristics of the shoppers. The processor (P1) also determines the retail outlets to which sample products should be provided based on the shoppers who are to receive the samples and the home retail outlet at which the shopper shops.
Patent NZ-563401-A (NZ)
Title: Polyinosinic acid-polycytidylic acid-based adjuvant
Inventor: LIN HAIXIANG
IPC: A61K39/39
Filed: 2005-06-08
Abstract: Provided is a polynucleotide adjuvant composition comprising a polyriboinosinic-polyribocytidylic acid (PIC), kanamycin, and a calcium ion, wherein the polynucleotide adjuvant composition has an average molecular weight greater than 138,269 Daltons or average molecular size greater than 9 Svedbergs, and a maximum molecular weight of 1,200,000 Daltons or a maximum molecular size of 24 Svedbergs. The adjuvant is useful in enhancing an immune response to an antigen in an animal.
Patent NZ-563739-A (NZ)
Title: 2,6 Quinolinyl derivatives, processes for preparing them and their use as medicament
Inventor: PERRY BENJAMIN
IPC: C07D401/12
Filed: 2006-05-22
Abstract: Disclosed are 2,6-quinolinyl derivatives of formula I, their enantiomers, diastereoisomers or pharmaceutical salts thereof, wherein R1 is hydrogen, hydroxyl, methoxy or alkyl; R2 is hydrogen or halogen; n is 0 to 5; R3 is hydrogen or halogen; n' is 0 to 4. Of particular importance are the compounds methyl-(2S)-2-[(3,5-dichloroisonicotinoyI)amino]-3-[2-(2,6-dichiorophenyl)-6-quinolinyl]propanoate and (2S)-2-[(3,5-dichloroisonicotinoyI)amino]-3-[2-(2,6-dichiorophenyl)-6-quinolinyl]propanoic acid. Also disclosed is the use of a compound as defined above in the manufacture of medicament for the treatment of alpha4beta7 and/or alpha4beta7 dependent inflammatory or medical conditions (such as asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, inflammatory skin disorders including dermatitis, psoriasis, urticaria, pruritus and eczema, rheumatoid arthritis, inflammatory bowel diseases including Crohn's diseases and ulcerative colitis, multiple sclerosis and other autoimmune disorders, acute myelogenous leukaemia, transplantation and atherosclerosis) or alpha4 related cancers.
Patent NZ-566319-A (NZ)
Title: Use of free L-proline in the preparation of supplements for supplementing the concentration of cellular free L-proline in abalone
Inventor: VOSLOO ANDRE
IPC: A61K31/401
Filed: 2006-09-19
Abstract: Disclosed is a supplement when used for supplementing the concentration of cellular free L-proline in abalone to limit the dehydration in abalone, wherein said supplement comprises an effective amount of free L-proline. Also disclosed is a method of restricting the dehydration of abalone during storage and transportation including the step of administering to abalone an effective amount of L-proline of between 50 and 200 g free L-proline, per between 2 and 20 kg dry mass of feed, with between 10 and 100 g dry feed being fed to between 2 and 20 kg, live abalone every 1 to 6 days.
Patent NZ-569418-A (NZ)
Title: Injection bolt with a fixed static mixer for use in securing a rock mass
Inventor: EIGEMANN ERNST AUGUST
IPC: E21D20/02
Filed: 2007-02-26
Abstract: Disclosed is an injection bolt for use in securing a rock mass. The bolt includes a shaft for insertion into a hole in the rock mass. The shaft has a profile and forms a profiled internal bore which includes an inlet suitable for connection to an anchoring material pump and an outlet for injecting anchoring material into the hole in the rock mass. The bolt further includes a static mixer for mixing multiple components of the anchoring material. The static mixer is fixed in place by the profile within the internal bore.
Patent NZ-569946-A (NZ)
Title: Cyclic peptides comprising cationic amino acids and their use as antifungals
Inventor: O'NEIL DEBORAH
IPC: C07K14/47
Filed: 2006-12-21
Abstract: The use of a cyclic peptide comprising 3 to 50 arginine amino acids in the manufacture of a medicament for treating a fungal infection. The infection can be a dermatophyte infection in particular a Tinea infection or an infection caused by the genera Trichophyton, Epidermophyton or Microsporum. The dermatophyte can be Trichophyton interdigitale or T. rubrum.
Patent NZ-576223-A (NZ)
Title: Intra-mammary teat sealant formulation and method of using same to reduce or eliminate visual defects in aged cheeses
Inventor: RANKIN SCOTT A
IPC: A61K33/24
Filed: 2007-10-10
Abstract: Disclosed is a method of forming a physical barrier in the teat canal of a non-human animal and simultaneously preventing black spot defect in dairy products made with milk from the animal, the method comprising: infusing an amount of a teat seal formulation into the teat canal of the animal, wherein the teat seal formulation comprises a bismuth-free, non-toxic amount of titanium dioxide, zinc oxide, barium sulphate, combinations thereof.
Patent NZ-584456-A (NZ)
Title: Laptop and portable electronic device wireless power supply system with a cradle movable between first and second positions providing support and power transfer in both positions
Inventor: BAARMAN DAVID W
IPC: G06F1/16
Filed: 2008-10-15
Abstract: A wireless power supply system is disclosed for inductively transferring power to a removable remote device (D1, D2). The system comprises an inductive power supply for generating an electromagnetic field, a cradle (92') and a primary coil (34). The cradle (92') is movable between a first position for supporting the remote device in a first orientation (2nd from right) on a first power transfer surface and a second position for supporting the remote device in a second orientation (far right) on a second power transfer surface. Each power transfer surface supports the remote device (D1, D2) within the electromagnetic field. A first primary (34) is coupled to the inductive power supply to generate the electromagnetic field and is disposed on or within the cradle (92'). The primary (34) is positioned to inductively couple with the remote device when placed in either the first orientation or the second orientation. An embodiment is also disclosed with a plurality of primaries (34 a-c) for generating a multiphase electromagnetic field.
Patent NZ-591012-A (NZ)
Title: A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
Inventor: GAO GUANPING
IPC: C12Q/
Filed: 2002-11-12
Abstract: Provided is an adeno-associated virus (AAV) comprising an AAVrh10 capsid having a sequence of amino acids 1 to 738 of a specified sequence or a sequence which is at least 95% identical therewith, a minigene having AAV inverted terminal repeats (ITRs), and a heterologous gene operably linked to regulatory sequences which direct its expression in a host cell.
Patent NZ-592340-A (NZ)
Title: A method for making a virus vaccine compising Replikin peptides
Inventor: BOGOCH SAMUEL
IPC: C12Q1/68
Filed: 2002-03-26
Abstract: Disclosed is a method of making a virus vaccine comprising: Identifying at least one Replikin sequence or at least one fragment of said at least one Replikin sequence in at least one protein or polypeptide of a virus, wherein said at least one Replikin sequence comprises 7 to 50 amino acid residues and comprises (1) at least one lysine residue six to ten amino acid residues from at least one other lysine residue, (2) at least one histidine residue, and (3) at least 6% lysine residues; and Making the virus vaccine comprising combining said at least one protein or polypeptide of said virus with a pharmaceutically-acceptable carrier and/or adjuvant.
Patent NZ-598439-A (NZ)
Title: Adhesive bandage with absorbent pad having interconnected channel regions of higher density than rest of pad and being visible from a distance, with raised portions each polygonal of four to eight sides
Inventor: CHAN JENNIFER WING-YEE
IPC: A61F13/533
Filed: 2012-02-27
Abstract: An adhesive bandage has a backing layer with an absorbent pad attached to it with adhesive. The pad has raised tufted regions separated by lower channel regions of a greater density than the raised regions. Each of the tufted regions is a polygon of four to eight sides.
Patent NZ-602651-A (NZ)
Title: Methods of applying physical stimuli to cells
Inventor: JUDEX STEFEN
IPC: C12N5/0775
Filed: 2009-03-02
Abstract: NZ 602651 Disclosed is a method of influencing the fate of an in vitro cultured stem or progenitor cell, the method comprising administering to the cell a mechanical signal on a periodic basis and for a time sufficient to influence the fate of the cell such that it differentiates into a cell type different from the cell type it would be expected to differentiate into in the absence of the mechanical signal, wherein the frequency of the mechanical signal is 10-100 Hz and the magnitude of the mechanical signal causes the cell to accelerate at 0.0981-39.24 m/s2.
Patent NZ-610682-A (NZ)
Title: Actuation of an intercepting apparatus
Inventor: LÉGERET Benoît
IPC: B66B5/20
Filed: 2011-12-09
Abstract: 610682 In the case of this lift installation (1), a car (not shown) contains an intercepting apparatus (11), which is arranged on the car and is intended for braking and securing the car as required on the guide rail (9) or on a braking rail. The intercepting apparatus (11) is connected to an arrangement for actuating the intercepting apparatus (18), it also being possible for this arrangement to actuate the intercepting apparatus (11). The arrangement for actuating the intercepting apparatus (18) contains a driving body (20), which can be pressed, if required, against the lift shaft, preferably against the guide rail or braking rail (9), wherein the intercepting apparatus (11) is actuated by relative movement between the intercepting apparatus (11) and the driving body (20) pressed against the lift shaft. The driving body (20) contains, for this purpose, a curved driving surface (21), which is brought into engagement, if required, with the lift shaft or with the guide rail or braking rail (9).
Patent NZ-610711-A (NZ)
Title: A device for traversing an object
Inventor: HAYDEN GARY JAMES
IPC: B66F11/04
Filed: 2011-10-19
Abstract: 610711 Disclosed is a device for traversing an object, such as a tree, a utility pole or a building. The device comprises a first gripping portion (10) and a second gripping portion (10’), each pivotally and rotatable coupled at each end of a manipulatable arm (see 35a/35b figure 10). The first and second gripping portions each comprise a pair of grappling legs (see 20a & 20b, figure 1) coupled to respective grappling leg displacement means, such as hydraulic cylinders (see 31a & 31b, figure 1). The grappling leg displacement means move the corresponding grappling legs between an open and closed position for respectively releasing and securing the corresponding gripping portion to an object. A controller is also provided for controlling the manipulatable arm and respective grappling leg displacement means so as to allow the device to traverse the object. Traversing is effected by securing one of the respective gripping portions to the object while the other is pivotally and/or rotatably moved to the desired location on the object for securing thereto. One of the first or second gripping portions may be substituted for a personnel carrier. A method for carrying out work about an object, including traversing the object, is also disclosed.
Patent NZ-611529-A (NZ)
Title: Glucagon receptor modulators
Inventor: ASPNES GARY ERIK
IPC: C07D405/12
Filed: 2011-12-09
Abstract: Disclosed herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon. In one embodiment the compound is 3-[(6-{ (S)-3-methyl-1-[2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-butylaminolpyridine-3-carbonylyamino]-propionic acid.
Patent NZ-611651-A (NZ)
Title: Sinomenine derivatives and processes for their synthesis
Inventor: BERBERICH DAVID W
IPC: C07D221/28
Filed: 2008-12-17
Abstract: Disclosed herein are sinomenine derivatives of formula (I), wherein the variables are as defined in the specification. Also disclosed is a process encompassing synthetic routes for the production of (+)-sinomenine derivatives and their intermediates. Sinomenine is an alkaloid isolated from the root of Sinomenium acutum, which is reported to possess anti-inflammatory, analgesic, blood pressure lowering, and anti-arrhythmia activities. Both the isolated molecule and the S. acutum plant have been used clinically in China for the treatment of rheumatoid arthritis.
Patent NZ-703538-A (NZ)
Title: Compounds and methods for kinase modulation, and indications therefor
Inventor: ZHANG YING
IPC: C07D487/04
Filed: 2011-04-20
Abstract: Disclosed are substituted fused bicyclic compounds which are pyrrole fused with either pyridine or pyrimidine of formula (I) and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on one or more of Fms, Kit, Flt3, TrkA, TrkB and TrkC kinase protein. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of one or more of Fms, Kit, Flt3, TrkA, TrkB and TrkC, including rheumatoid arthiritis, osteoarthritis, osteoporosis, peri-prosthetic osteolysis, systemic sclerosis, demyelinating disorders, multiple sclerosis, Charcot Marie Tooth syndrome, amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, global ischemia, ulcerative colitis, Crohn’s disease, immune thrombocytopenic purpura, atherosclerosis, systemic lupus erythematosis, myelopreparation for autologous transplantation, transplant rejection, glomerulonephritis, interstitial nephritis, Lupus nephritis, tubular necrosis, diabetic nephropathy, renal hypertrophy, type I diabetes, acute pain, inflammatory pain, neuropathic pain, acute myeloid leukemia, melanoma, multiple myeloma, breast cancer, prostate cancer, pancreatic cancer, lung cancer, ovarian cancer, gliomas, glioblastoma, neurofibromatosis, osteolytic bone metastases, brain metasteses, gastrointestinal stromal tumors, and giant cell tumors. Examples of compounds of formula (I) are: [5-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3 -ylmethyl)-pyrimidin-2-yl]-cyclohexyl-amine, [5-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyrimidin-2-yl]-cyclopentyl-amine, [5-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyrimidin-2-yl]-cyclobutyl-amine, and Cyclohexyl-[6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-amine.
Patent NZ-708243-A (NZ)
Title: Active compound combinations comprising carboxamide derivatives and a biological control agent
Inventor: CRISTAU PIERRE
IPC: A01N43/56
Filed: 2013-10-17
Abstract: The present invention relates to an active composition comprising (A) N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide, or an agrochemically acceptable salt thereof, and (B) at least Bacillus pumilus strain QST2808. Moreover, the invention relates to a method for controlling the phytopathogenic fungi of plants or crops, and to the use of a combination according to the invention for the treatment of seed. The active composition of the present invention achieves a substantial broadening of the spectrum of phytopathogens that can be controlled as well as increased safety in use.