baber/WOPTO huggingface dataset:
Patent AT-E310505-T1 (AT)
Inventor: BYRA ANNA R
IPC: A61K31/19
Filed: 1997-05-14
Granted: 2005-12-15
Abstract: A second generation of antineoplaston therapies with markedly improved antineoplastic activity is disclosed. Among others, members of the antineoplaston family include phenylacetate (PN), 3-phenylacetyl-amino-2, 6, piperidinedione (CN), and hydrolysis derivatives of CN: phenylacetylglutamine (PG) and isophenylacetylglutamine (Iso-PG). In part, these increases in antineoplastic activity result from large increases in the transport of antineoplaston compositions into cells. Importantly and unexpectedly these increases in antineoplastic activity also result from the capacity of the drug delivery system to direct antineoplaston compounds intracellular trafficking to intracellular binding sites influencing cell viability and proliferation. Liposomal formulations of antineoplaston compositions increase in vitro antineoplastic activity by a factor of 750 to 1500 as compared to administration of antineoplaston compounds given without liposomal formulations. In addition, these liposomal formulations enhanced cellular uptake of antineoplaston compounds from 30 to more that 80 fold. Liposomal formulations were also found to increase intracellular levels of the antineoplaston CN (3-phenylacetyl-amino-2,6, piperidinedione) by directing CN to intracellular binding sites that influence cell viability and proliferation and block its hydrolysis. Under conditions where free CN has no antineoplastic activity, liposomally formulated CN can produce essentially complete and relatively long-lasting blockade of cell growth. Cell growth was found to be restored as intracellular levels of bound CN decrease to undetectable levels.
Patent AT-E387208-T1 (AT)
Inventor: TSAI HSIU-HSIEN
IPC: A61K36/00
Filed: 1997-07-09
Granted: 2008-03-15
Abstract: This invention relates to compositions derived from Chinese herbal medicines, medicinal plants and extracts thereof, and to their use for the treatment of animals infected with viruses, especially with hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). More specifically, the compositions of the present invention arc derived from various Chinese herbal medicines or medicinal plants which have a long history of human consumption. The compositions of the invention are obtained through specific techniques and have demonstrated outstanding efficacy for treating human HBV carriers and hepatitis C patients. Compositions according to the invention have also exhibited in vitro antiviral activities against murine leukemia virus (MuLV) and HIV. HIV is the virus known to cause acquired immunodeficiency syndrome (AIDS) in humans and AIDS presents special problems to the medical community which the present invention addresses.
Patent AT-E230793-T1 (AT)
Inventor: BEHRENDS SABINE
IPC: A61K8/00
Filed: 1997-10-29
Granted: 2003-01-15
Abstract: A disinfectant composition and process for making the same. The composition comprises octenidine dihydrochloride, at least one C<SUB>1 </SUB>to C<SUB>8</SUB>-alkyl alcohol, at least one surfactant chosen among non-ionic or cationic surfactants, water and optionally at least one alpha-hydroxycarboxylic acid.
Patent AT-E221498-T1 (AT)
Inventor: LARSON RAYMOND L
IPC: B65B9/20
Filed: 1997-12-11
Granted: 2002-08-15
Abstract: A liquid product carrying plastic film pouch (10) having a straw (12) free-floating in the liquid product (11) is described. The liquid product (11) contained within the inner chamber (13) of the pouch occupies from about 60 % to about 90 % of the volume of the inner chamber (13) of the pouch and a portion of air from the remaining volume is evacuated in sufficient quantity to permit the side walls (14, 15) of the pouch to be collapsed against one another when the pouch is grasped by the hand of a user person. By collapsing the side walls (14, 15) together the straw (12) located within the liquid can be grasped and manipulated to puncture the plastic film pouch (1) to extend a portion (12') of the straw (12) exteriorly of the pouch whereby to extract liquid therefrom. The pouch (10) is made of a multilayer resin film having an inner sealant layer (26) formed of a linear low density ethylene-octene copolymer or very low density ethylene copolymer (octene or other copolymers) such that when the straw punctures the film, the inner sealant layer (26) forms a membrane about the straw which exhibits a self-sealing behavior so as to prevent leakage in the punctured region as liquid is extracted from the pouch (10) through the straw (12). The machine and method of fabrication is also disclosed.
Patent AT-E242616-T1 (AT)
Inventor: LOEHN GERD
IPC: A61C1/08
Filed: 1998-07-03
Granted: 2003-06-15
Abstract: The dental or surgical instrument (1) has a handle (3) which can be joined to a water or compressed air supply duct (21,22) with a coupling device (4) consisting mainly of a bolt (6) attached to the duct (21,22) and an indent (5) at the handle (3). A ring seal (23) accommodated in a circular groove (24) and slightly wider than the supply duct (21) has one main opening (32) in the centre and openings (25,29) on both sides of the supply duct (21,22).
Patent AT-E282871-T1 (AT)
Inventor: BUSCH FRITZ DR
IPC: G08G1/01
Filed: 1998-09-10
Granted: 2004-12-15
Abstract: The method involves using fixed detectors to form local detection cross-sections for the detection of traffic-related measurement values. The values are pre-processed by local computers and standardized to a defined data format, aggregated and wirelessly passed to a superior data processing system. The locally aggregated data are statistically evaluated and smoothed, set relative to a predefined reference value and only transferred if the results exceeds or lies below a threshold region determined using the reference.
Patent AT-E219202-T1 (AT)
Inventor: PREVOT GERARD
IPC: E05B63/06
Filed: 1998-03-31
Granted: 2002-06-15
Abstract: The locking mechanism has an adjustable bolt (7) for a sliding door, window or similar with a bolt carrier (4). The carrier has at least one slot (5) to receive the shank (6) of the bolt, which has at least one hook (8a, 8b). The bolt carrier is designed to slide transversely relative to the slot to enable the hook(s) to engage with or disengage from a catch plate on the fixed surround of the door or window. The bolt is made so that it can be moved lengthwise in the slot to adjust its position relative to the catch plate, and it is fixed in position by means of an aperture (21) extending in the same direction as the slot and a locking screw (16) which engages with the edges of the aperture. The bolt can have either one aperture in line with its lengthwise axis or two apertures lying symmetrically relative to the axis.
Patent AT-E232961-T1 (AT)
Inventor: CARPENTIER PIERRE
IPC: F28D9/00
Filed: 1998-08-03
Granted: 2003-03-15
Abstract: Space between the heat exchanger casing and a series of flat parallel tubes containing high temperature fluid is used to circulate lower temperature fluid. The heat exchanger has a first series of flow channels for a first high temperature fluid, made from thermally conducting material and a second series of flow channels for a second fluid at a lower temperature, also made from a thermally conducting material. These channels intercept perpendicularly so as to ensure heat transfer between the first and second fluids. Each channel is of oblong shape and is divided by insertion of a thermally conducting material fixed to the long internal channel faces on a number of internal channels. The first series of channels are formed from flat parallel tubes (7) juxtaposed in the direction perpendicular to the large axis of their transversal section at pre-set distances between two exterior lateral plates (8). These plates are parallel to the tubes in a casing (9) which is open other lateral faces and is maintained at the top and bottom by input and output collector plates (13, 14) of collector inputs (2) and outputs (3), in which the tubes (7) terminate. The channels of the second series are formed in the spaces between the exterior of the tubes (7) and the plates of the casing (9).
Patent AT-E205440-T1 (AT)
Inventor: OLSCHEWSKI KARL HEINZ
IPC: B29C45/17
Filed: 1998-01-16
Granted: 2001-09-15
Abstract: The invention relates to a device for injection moulding plastic pieces (8) with at least one blowhole (10) created by injection of gas (G), which pushes the melted plastic matter (4) from the blowhole area (3) into a secondary blowhole (10) by means of a channel (K)_fitted in the mould. The channel (K) widens continuously, particularly conically, from the blowhole area (3) to the secondary blowhole (10).
Patent AT-E221613-T1 (AT)
Inventor: BEAUQUIN JEAN-LOUIS
IPC: F04D13/10
Filed: 1998-01-28
Granted: 2002-08-15
Abstract: The invention concerns a pumping installation designed for being mounted in an oil well extending from the surface to a layer of oil-bearing rock, comprising a pipe column at the lower end of which is mounted a pump, a joint, mounted in the well around the pipe column and delimiting a chamber at the lower end of the well, in which is arranged a pump. The installation further comprises a hydro-ejector, in the pipe column, including a lower pressure zone opening into the upper end of the chamber.
Patent AT-E225680-T1 (AT)
Inventor: STEPANIUK NICHOLAS
IPC: B01J19/18
Filed: 1998-02-10
Granted: 2002-10-15
Abstract: PCT No. PCT/US98/02634 Sec. 371 Date Mar. 9, 1999 Sec. 102(e) Date Mar. 9, 1999 PCT Filed Feb. 10, 1998 PCT Pub. No. WO98/34633 PCT Pub. Date Aug. 13, 1998A solid phase peptide synthesis reactor system and method of operating the reactor are provided. The reactor system includes a basket rotatable about an axis within a housing and a receiver which delivers fluid to, and collects fluid from, the housing. The basket has a perforate side wall against which a resin cake for the peptide synthesis is formed. The reactor and receiver form a loop or circuit through which solutions are circulated. The circulation of the solutions prevents the reactor from flooding so that the basket will not be submerged in solution and allows for the use of less liquid. Thus greater amino acid concentrations may be used. The method includes forming a resin cake of uniform depth on the wall of the spinning basket and spraying the solutions against the resin cake while spinning the basket. The solutions will pass through the resin cake and drain to the receiver to be circulated or recycled through the system or discharged from the system. Before a subsequent solution is introduced into the reactor system, the prior solution is purged from the system to help control exposure time of the peptide to the solutions.
Patent AT-E232093-T1 (AT)
Inventor: JOSHI RAJENDRA K
IPC: A61P9/02
Filed: 1998-04-01
Granted: 2003-02-15
Abstract: Disclosed is a method of treating auto-immune diseases by the administration of certain fumaric acid monoalkyl esters as salts or free acids thereof either alone or in combination with a dialkyl fumarate.
Patent AT-E527358-T1 (AT)
Inventor: STIRPE FIORENZO
IPC: A61K38/00
Filed: 1998-06-08
Granted: 2011-10-15
Abstract: The invention relates to a novel ribosome-binding protein derived from Bougainvillea spectabilis having a molecular weight of about 26,000 daltons by polyacrylamide gel electrophoresis under reducing and non-reducing conditions, a pI of about 9.0, and a specified amino-terminal amino acid sequence. The invention further relates to a conjugate of the protein with a targeting ligand, such as an antibody, to form an immunotoxin. The protein and the conjugate are useful in therapy, for example, in the control of tumour cells or viruses.
Patent AT-E246972-T1 (AT)
Inventor: SUNAGA JUNICHI
IPC: B26F1/00
Filed: 1998-09-01
Granted: 2003-08-15
Abstract: In a process for producing precise cut surfaces on a workpiece by stamping or blanking, in particular by fine-edge blanking, a contour first is stamped or blanked out at a distance (a) from the actual contour of the workpiece, and the workpiece then is scraped down to its final contour. It is intended here, in a first step, for only up to part of the thickness (d) of the workpiece to be scraped and, in a following step, for the contour of the workpiece to be achieved by scraping in the opposite direction to the first step.
Patent AT-E254942-T1 (AT)
Inventor: WALDECK FRANZ
IPC: A61M16/04
Filed: 1998-08-08
Granted: 2003-12-15
Abstract: The invention relates to a tracheotomy cannula (100), comprising a pipe-or tube-shaped element for passing the cannula through a throat or trachea incision into the trachea of a patient whose upper airways are blocked, so as to supply said patient with air through the cannula (100). A shield (21, 22) is attached to the cannula (100) which rests against the neck of the patient and in so doing determines the position of the cannula or of the end of the cannula (100) in the trachea of the patient. To create a tracheotomy cannula (100) having the above features which can be easily adjusted to fit the anatomical characteristics of a patient and requires no special effort regarding the stock-keeping and adjustment of tracheotomy cannulas (100), the invention provides for the shield (21, 22) to be fixably attached to the cannula (100) in various positions in the longitudinal direction of the cannula (100).
Patent AT-E241211-T1 (AT)
Inventor: JOELLENBECK ANDRE
IPC: H01H85/00
Filed: 1998-08-29
Granted: 2003-06-15
Abstract: An electrical fuse element (1), which comprises a substrate (4) with two contacts (2) arranged on opposite end sides (3), terminal areas (7) connected to the contacts and a fusible conductor (10) electrically connected in a conducting manner to the contacts via the terminal areas, is developed for use in higher voltage ranges, with improved breaking capacity and with low production costs, by the terminal areas (7) and the fusible conductor (10) being arranged separated from one another by an insulator (4) and electrically connected to one another via lead-throughs.
Patent AT-E260144-T1 (AT)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B65D83/76
Filed: 1998-10-16
Granted: 2004-03-15
Abstract: The invention relates to a device for assembling and packaging a pump (P) and a receptacle (R) of the type comprising firstly a fixing bush (1) provided on its inside wall with elastically deformable elements (11) for fastening beneath a collar (C) of the neck of the receptacle (R), and secondly with a packaging skirt (2) that is malleable, at least in part, clamped radially against the outside wall of said bush (1), the device being characterized in that said bush (1) has setbacks (10) formed in its outside wall in register with the fastener elements (11), defining an intermediate empty zone in which said skirt (2) is not liable to be deformed by said elements (11).
Patent AT-E373957-T1 (AT)
Inventor: NEMEROFF CHARLES
IPC: A61K9/00
Filed: 1998-10-09
Granted: 2007-10-15
Abstract: A method and device for treating acute mania or bipolar disorder is disclosed, by transdermal delivery of Li+ at substantially constant rate through the skin via a dermal patch.
Patent AT-E237176-T1 (AT)
Inventor: BALAKRISHNAN SREERAM
IPC: G10L15/18
Filed: 1998-11-19
Granted: 2003-04-15
Abstract: A method and apparatus for generating a context dependent phoneme network as an intermediate step of encoding speech information. The context dependent phoneme network is generated from speech in a phoneme network generator (48) associated with an operating system (44). The context dependent phoneme network is then transmitted to a first application (52).
Patent AT-E359824-T1 (AT)
Inventor: O CONNOR BARBARA H
IPC: A61K9/08
Filed: 1993-07-29
Granted: 2007-05-15
Abstract: A stable pharmaceutically acceptable aqueous formulation containing human growth hormone, a buffer, a non-ionic surfactant, and, optionally, a neutral salt, mannitol, or, a preservative, is disclosed. Also disclosed are associated means and methods for preparing, storing, and using such formulations.
Patent AT-E293171-T1 (AT)
Inventor: LAER MEIKE-DOROTHEE VON
IPC: A61K48/00
Filed: 1999-11-25
Granted: 2005-04-15
Abstract: A retroviral packing cell (I), comprising the retroviral genes gag, pol and glycoproteins GP-1 and GP-2 of the LCMV coding gene gp, or a part of these, is new. Independent claims are also included for the following: (1) preparation of (I); (2) a retroviral packing cell (II) expressing pseudo-type virions, which contain LCMV glycoproteins in their coat; (3) pseudo-type virions (III) produced by (II); (4) a retroviral pseudo-type vector (IV), produced by cultivating (I); (5) preparation of (IV); (6) a lymphocyte Choriomeningitis virus (V), comprising the gene gp, which encodes the 498 amino acid sequence, fully defined in the specification, or a part of it; (7) a protein (VI) having the fully defined 498 amino acid sequence, or a part of it; and (8) a nucleic acid sequence (VII) having the fully defined 1497 base pair sequence, or a part of it.
Patent AT-E252405-T1 (AT)
Inventor: GUALA GIANNI
IPC: A61M39/28
Filed: 1999-08-26
Granted: 2003-11-15
Abstract: Roller clamp (1) for regulating a fluid flow through an elastically deformable tubing (T), comprising a generally channel-shaped body (2) and a roller (3) longitudinally movable in a guided fashion parallelly to a clamping surface (6) of the bottom wall (4) of the body (2) so as to clamp the elastically deformable tubing (T). Longitudinal lateral recesses (17) are formed between the clamping surface (6) and the lateral walls (5) of the body (2), at least along part of a longitudinal central groove (7) having a decreasing section of the bottom wall (4), which are designed to accommodate elastic expansion of the tubing (T) being clamped. <IMAGE>
Patent AT-E243224-T1 (AT)
Inventor: CHEN PETER
IPC: C08F2/00
Filed: 1999-01-22
Granted: 2003-07-15
Abstract: This invention relates to a process for carrying out an anionically or cationically catalytically accelerated gas phase reaction and particularly relates to a process for carrying out a catalytically accelerated gas phase polymerization reaction. The process involves the step of introducing a catalyst ion into a gaseous reaction mixture as a free anion or cation without a corresponding counterion and substantially solvent free. The catalyst of this invention ca, for example, be a Ziegler-Natta catalyst or a metallocene catalyst. The gas phase reaction that is catalyzed can, for example, be a metathesis reaction, a metathesis ring-opening polymerization reaction, or a gas phase polymerization.
Patent AT-E241658-T1 (AT)
Inventor: BACK GAYLE EDWARD
IPC: C08G59/50
Filed: 1999-03-03
Granted: 2003-06-15
Abstract: A water-dispersible curing agent for epoxy resins is prepared by the reaction of (a) an epoxy-functional compound obtained from the reaction of at least one epoxy resin and an amidoamine derived from the reaction of an acid-terminated polyalkylene glycol and a diamine in an active amine hydrogen:epoxy groups ratio of from 1:15 to 1:350, (b) at least one polyamine in an active amine hydrogen:epoxy groups ratio of from 2:1 to 30:1 which yields an amine-terminated product having an amine equivalent weight of at least 50, and, optionally, (c) a monoepoxy in a remaining active amine hydrogen:epoxy groups ratio of from 5:1 to 20:1.
Patent AT-E239556-T1 (AT)
Inventor: TAYLOR ALISTAIR STEWART
IPC: B05C3/09
Filed: 1999-07-21
Granted: 2003-05-15
Abstract: The invention provides an apparatus for coating tubular members, such as stents, and also provides a method for coating tubular members. The invention improves manufacturing efficiencies of existing manual-dipping technology for stents and also addresses manufacturing problems from stents having plural surface apertures associated with the presence of excess liquid, inconsistent drying of the liquid and blockage.
Patent AT-E304574-T1 (AT)
Inventor: LANDA ADRIE
IPC: C08L71/12
Filed: 1999-07-22
Granted: 2005-09-15
Abstract: The present invention relates to flame retardant compositions of compatibilized polyphenylene ether-polyamide resin blends containing at least one phosphoramide compound. The present invention also relates to articles made from the resin compositions as well as methods to make flame retardant compositions of compatibilized polyphenylene ether-polyamide resin blends.
Patent AT-E394071-T1 (AT)
Inventor: SPENCE PAUL
IPC: A61B17/00
Filed: 1999-05-27
Granted: 2008-05-15
Abstract: A system for manipulating a heart during cardiac surgery permits coronary surgery on a beating heart while maintaining cardiac output unabated and uninterrupted. Circumflex coronary artery surgery can be performed using the system. A component of the system engages the heart with a heart positioning device, repositions the heart into a displaced position and maintains it in the displaced position while the heart continues to beat with substantially unabated and uninterrupted cardiac output. One form of the system can be used in minimally invasive surgery.
Patent AT-E245618-T1 (AT)
Inventor: MOELLBY NILS
IPC: C07C41/38
Filed: 1999-09-28
Granted: 2003-08-15
Abstract: A method used in a recovery of trimethylolpropane triallyl ether and/or trimethylolpropane diallyl ether from a mixture comprising said triallyl ether and said diallyl ether. The method comprises distilling said mixture at a pressure of less than 12 kPa, such as less than 10 kPa, in a distillation column in the presence of an effective amount of at least one polar or non-polar extractive agent, a so called entrainer. The extractive agent is preferably at least one alcohol, alkanolamine or aliphatic hydrocarbon.
Patent AT-E493971-T1 (AT)
Inventor: BOSCH H
IPC: A61J3/02
Filed: 1999-11-12
Granted: 2011-01-15
Abstract: The invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the formulations in aerosol delivery devices, and methods of making such formulations. The nanoparticles of the aqueous dispersions or dry powder formulations comprise insoluble drug particles having a surface modifier on the surface thereof.
Patent AT-E419549-T1 (AT)
Inventor: YIP BRANDON
IPC: G02B1/10
Filed: 1999-11-19
Granted: 2009-01-15
Abstract: A coated optical lens includes a lens element and a coating on the surface of the lens element. The coating exhibits a substantially balanced reflectance from the center to a radius proximate the edge of the lens element. The term "substantially balanced reflectance" means that where the thickness of the coating varies across the surface of the lens, the lightness, hue and chroma of the reflectance vary in a balanced manner such that variations in visual appearance are either imperceptible or generally acceptable to an observer. For example, variations in chromatic attributes, such as hue, from the center to the edge of the lens may be balanced by a reduction in lightness from the center to the edge. Preferably, the lens element includes a surface of high curvature upon which the balanced reflectance coating is deposited.
Patent AT-E231197-T1 (AT)
Inventor: HUNTER CHARLES ERIC
IPC: C30B29/36
Filed: 1999-10-08
Granted: 2003-02-15
Abstract: Low defect density, low impurity bulk single crystals of AlN, SiC and AlN:SiC alloy are produced by depositing appropriate vapor species of Al, Si, N, C on multiple nucleation sites that are preferentially cooled to a temperature less than the surrounding surfaces in the crystal growth enclosure. The vapor species may be provided by subliming solid source material, vaporizing liquid Al, Si or Al-Si or injecting source gases. The multiple nucleation sites may be unseeded or seeded with a seed crystal such as 4 H or 6 H SiC.