baber/WOPTO huggingface dataset:
Patent UY-25127-A1 (UY)
Title: Metodo para preparar acidos 4-fenil-4-ciano-ciclohexanoicos sustituidos
Inventor: WEBB KEVIN
IPC: A61K31/277
Filed: 1998-08-06
Abstract: Esta invención se refiere a compuestos intermedios y a una vía de síntesis para producir ácido 4-ciano-4-(3-ciclo-pentiloxi-4-metoxifenil)ciclohexanoico y sus análogos. Este ácido y sus análogos mencionados son selectivos respecto a la inhibición del sitio catalítico en la isoenzima de la clase de las fosfodiesterasas, los ácidos son útiles en el tratamiento de enfermedades que pueden ser moderadas por afectar la enzima PDE IV y subtipos. Esta invención se refiere a un método para producir un compuesto de fórmula (I) en la cual R1 es -(CR4R5)nC(O)O(CR4R5)mR6 donde los restos de alquilo pueden estar sustituídos con uno o mas halógenos; m es de 0a2; n es 1a 4, r es 0a6; R4 y R5 se seleccionan independientemente de H o alquilo C1-2;R6 es H , metilo, hidroxilo, arilo, arilo sustituído con halo, indanilo, indenilo, etc; X es YR2, halógeno, haloógeno, nitro, NH2, formilamina; X2 es O,; Y es O o S(O)m´; m´es 0,1 ó 2R3 es H, halógeno, alquilo C1-4; R´y R´´ son H o -C(O)OH. Ejemplo: Preparaciòn de 3-ciclopebtiloxi-4-metoxibenzaldehído
Patent UY-25172-A1 (UY)
Title: Curación de fracturas utilizando análogos pthrp
Inventor: VICKERY BRIAN HENRY
IPC: C07K14/635
Filed: 1998-09-07
Abstract: La presente invención proporciona métodos de cicatrización de hueso y reparación de fracturas que comprenden la administración a un paciente que lo necesite de una cantidad eficaz de un análogo polipeptídico del péptido relacionado con la hormona paratiroidea (PTHrP) y de sales del mismo, en el cual los residuos aminoacídicos 22-31 forman una hélice alfa anfipática, en la cual dicha hélice es GLU LEU LEU GLU Xaa LEU LEU GLU LYS donde Xaa es un residuo aminoacídico cargado positivamente para la preparación de un medicamento para el tratamiento de dichos trastornos. Se demostró que los análogos monocíclicos y bicíclicos de PTHrP (1-34) y PTHrP (7-34) se unen fuertemente con el receptor de PTH y estimulan (o antagonizan) la actividad adenilciclasa estimulada por PTH en las células similares a osteoblastos. Deberá tenerse en cuenta que pueden estar presentes en lo análogos de PTHrP empleados en la presente invenció aminoácidos tanto naturales como no naturales.
Patent UY-27167-A1 (UY)
Title: Inhibidores de piridina de metaloproteinasas de la matriz
Inventor: BARVIAN NICOLE CH
IPC: A61P/
Filed: 2002-02-13
Abstract: Inhibidores selectivos de MMP-13 son derivados de pirimidina de la fórmula I, o una sal farmacéuticamente aceptable del mismo, que inhiben las enzimas metaloproteínasas de la matriz y, así, son útiles para tratar enfermedades que resultan de la disgregación de tejidos tales como enfermedades del corazón esclerosis múltiple, osteoartritis y artritis reumatoide, aterosclerosis y osteoporosis
Patent UY-30318-A1 (UY)
Title: Dispositivo de pesca banzare deep line
Inventor: GARCIA JOSE NOGUEIRA
IPC: A01K73/12
Filed: 2007-05-02
Abstract: Dispositivo de pesca denominado Banzare Deep Line de acuerdo a una línea madre de la cual salen líneas secundarias, brazoladas, que mediante el dispositivo de proteccion DBDL conformado por dos aros, uno superior de diámetro inferior al otro unidos por un cono de red truncado movil el cual tanto en arriado de línea como en izado va a proteger o las carnadas o las piezas capturadas evitando con esto las perdidas de captura por la incidencia de cetáceos y la erradicacion de la mortandad de aves marinas por captura de carnadas, que mediante la nueva disposicion de los pesos y las protecciones provocará que la línea se hunda sin riesgos para el ecosistema.
Patent DZ-1376-A1 (DZ)
Inventor: FEDDERSPIEL ERIC
IPC: F16L47/03
Filed: 1989-12-20
Granted: 2004-09-13
Abstract: The invention concerns a device for detecting variations in the physical state of the plastic material in a coupling piece used for welding pipes and incorporating a heating resistor, cavities which the softened material can enter and sensors for detecting the state of the material within the cavities. According to the invention, in order to obtain a weld of high quality, it is necessary for the distance between the bottom of the cavities and the part of the resistor nearest this bottom on the one hand, and for the linear dimension in the cross-section of these same cavities near their bottom on the other, to be less than or equal to the thickness of the material which is softened during the heating of the pieces. The invention applies to the control of the welding of sections of piping, particularly for the gas industry.
Patent ES-158654-A1 (ES)
Title: PERFECCIONAMIENTOS EN A CONSTRUCCIoN DE CASCOS DE BUQUES
Filed: 1942-09-19
Abstract: Perfeccionamientos en la construcción de cascos de buques cuyo casco consta de chapa metálica especialmente chapa de metal ligero caracterizados por el hecho de que las distintas chapas de acorazamiento están achaflanadas rectangularmente en sus bordes longitudinales par ala formación de una costura asequible a las herramientas de remachado a presión y de que con su dirección longitudinal están situadas están situadas aproximadamente en la dirección longitudinal del buque.
Patent ES-172485-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA PRODUCCIoN DE NITRATO AMoNICO
Filed: 1946-02-07
Abstract: Un procedimiento para la producción de nitrato amónico en forma granular que comprende; pulverizar a temperatura superior a la suya de saturación una solución acuosa de nitrato amónico que tenga una temperatura de saturación comprendida entre 115º C y 135º C en un medio enfriador gaseoso mantenido a una temperatura inferior con lo cual la superficie exterior de cada gotita individual se enfría bruscamente y cristaliza en forma de cubierta; enfriar los gránulos a una temperatura inferior a 84º C en el medio enfriador gaseoso separar los gránulos de la etapa de pulverización del proceso y secarlos en un medio secador gaseoso calentado para eliminar la mayor parte del contenido de humedad de los gránulos y enfriar y secar a continuación los gránulos en un medio secador gaseoso mas frío para reducir el contenido de humedad de los gránulos a menos de 0 05 %.
Patent ES-184064-A1 (ES)
Title: PERFECCIONAMIENTOS DE LA FABRICACIoN DE CONMUTADORES DE ONDAS N LOS APARATOS DE RADIORRECEPCIoN
Filed: 1948-06-10
Abstract: Perfeccionamientos en la fabricación de conmutadores de ondas en los aparatos de radio-recepción caracterizados esencialmente por el hecho de disponer el camino de rodamiento para la conmutación a base de una corona circular de superficie ondulada formando sucesivos declives en sentidos opuestos reunidos entre sí por aristas suaves sin tener plano alguno que produzca punto muerto.
Patent ES-195209-A1 (ES)
Title: MEJORAS EN LA CONSTRUCCIoN DE PLATOS DEL PLEGADOR
Filed: 1950-11-03
Abstract: Mejoras en la construcción de platos del plegador caracterizadas porque el cubo del plegador maestra un torneado central cónico y está previsto un anillo de cono de presión hendido axilmente que se ajusta en este torneado al lado de un atornillamiento que empuja al anillo de cono en el torneado de manera que aquél y por ello el plato se aprietan sobre el plegador.
Patent ES-199954-A1 (ES)
Title: UN DISPOSITIVO QUE PERMITE LA EXPLORACIoN DE UNA IMPEDANCIA CARACTERiSTICA.
Filed: 1951-10-10
Abstract: Dispositivo probador para ser usado en instalaciones de señalización automática, para la prueba selectiva de impedancias de caracterización, el valor de cada una de las cuales representa una indicación de un aparato asociado con la misma, estando conectada la impedancia de caracterización a un punto de conexión múltiple que asociado con el aparato, es conectado durante la prueba al dispositivo probador y es simultáneamente accesible para una pluralidad de otros dispositivos probadores, en que la prueba de la impedancia de caracterización se lleva a cabo por medio de una corriente de prueba de la impedancia de caracterización se lleva a cabo por medio de una corriente de prueba que pasa por la impedancia de caracterización, el punto de conexión múltiple y el dispositivo probador, caracterizado por el hecho de que el aparato es marcado además por una tensión marcada cuyo valor provee una indicación si la impedancia de caracterización es probada o no, comprendiendo el dispositivo probador medios probadores capaces de responder a la presencia de la tensión marcadora que corresponde a la condición en la cual la impedancia de caracterización no es probada, siendo conectada la corriente de prueba a través de la impedancia de caracterización cuando los referidos medios probadores responden, y efectuándose la conexión de la corriente de prueba bajo el gobierno de los referidos medios probadores, siendo variada luego la tensión marcadora a un valor que corresponde a la condición en la cual la impedancia a un valor que corresponde a la condición en la cual la impedancia de caracterización es probada, haciendo pasar a través de una impedancia asociada con el aparato y conectada al punto al cual es aplicada la tensión marcadora, una corriente que difiere de la corriente de prueba.
Patent ES-251668-A1 (ES)
Title: Varnish resins consisting of chlorinated polypropylene or chlorinated copolymers of ethylene and propylene and process for their manufacture
IPC: C09D123/28
Filed: 1959-08-22
Abstract: Chlorinated homopolymers of propylene, and/or copolymers of propylene and ethylene, are made by introducing chlorine into a suspension of the polymers, in a low boiling halogenated hydrocarbon, at a temperature within the range of 40 DEG to 115 DEG C., and continuing the chlorination until the product contains at least 25% by weight of chlorine. The halogenated hydrocarbon is generally selected from bromotrichloromethane, tetrachlorethane, fluorochlorethanes, methylene chloride, chloroform, trichlorethane, tetrachloroethylene, and trichlorethylene. The polymers chlorinated may be subjected to a chlorination treatment, in the absence of an organic dispersing agent, to give a chlorinated product containing at least 20% by weight of chlorine. The chlorination may be accelerated by ultra-violet irradiation, working under superatmospheric pressure, or by using a free-radical substance such as a peroxide. The chlorinated polymers may be used in the lacquer and varnish industry admixed with conventional stabilizers and fillers. Specification 799,952 is referred to.
Patent ES-268289-A1 (ES)
Title: Process and apparatus for the polymerization of ethylene
IPC: C08F2/00
Filed: 1961-06-16
Abstract: In a process for polymerizing ethylene at high pressures by continuously pumping ethylene through a highly elongated tube, the improvement which comprises dissipating electricity from the surfaces of the let-down valve at the end of the tube, whereby the build up of electric charges and consequent explosive decomposition is avoided. Advantageously the valve housing is electrically connected to the valve stem by a flexible metal conductor, preferably of copper. In the example ethylene, preferably of 99.9% purity, is polymerized using oxygen as catalyst in a particularly described apparatus wherein the system or surfaces thereof may be of stainles steel.
Patent ES-309282-A1 (ES)
Title: Device for equalizing the tension in a filament
IPC: B65H59/18
Filed: 1965-02-12
Abstract: A device for maintaining a constant tension in a yarn comprises a cylinder rotated at a peripheral speed greater than the rate at which the yarn travels and in the same direction, means to guide the yarn to travel through at least one arc in contact with the cylinder and including at least two yarn guides mounted so as to move when the tension rises so as to increase the length of at least one of the arcs, and means tending to move the guides in a direction which decreases the length of the arc. Yarn 6 passes over a driven roller (1), guides (21, 2) and over the roller again. Roller 1 is driven faster than the yarn travels and the guides (2, 21) which may be pulleys are on arms (3, 31) which can rock about pivots (4, 41) against the pull of a spring (5) when the tension rises, to increase the extent which the yarn embraces the roller. The value of the working tension may be set by varying the force of the spring, or by changing the roller for one with a different surface. The spring may be replaced by a counterweight, a pneumatic device or an electromagnetic device. In another form the yarn enters and leaves the device over fixed guides arranged respectively before and after the guides (2, 21), the yarn in this case making one arc of contact with the roller.
Patent ES-317079-A1 (ES)
Title: Alpha-carboxyacylamino penicillins
IPC: C07D499/00
Filed: 1965-09-03
Abstract: The invention relates to penicillins of Formula I <FORM:1057697/C2/1> and non-toxic salts thereof, where R is an alkyl, aralkyl, aryl or heterocyclic group which may be substituted and X is a direct linkage or a divalent aliphatic, aromatic or heterocyclic radical which may be substituted. The penicillins are produced by (A) reacting an a -amino-penicillin of Formula II <FORM:1057697/C2/2> with a reactive derivative of the dicarboxylic acid HOOC-X-COOH, where R and X have the above meanings (B) catalytically hydrogenating an intermediate penicillin of Formula III <FORM:1057697/C2/3> wherein R1 is benzyl or substituted benzyl and R and X have the above meanings. The said intermediate penicillin is prepared by reacting (a) the appropriate a -amino-penicillin with a reactive derivative of the acid R1OOC-X-COOH or (b) 6-aminopenicillanic acid with a reactive derivative of the acid <FORM:1057697/C2/4> wherein R, R1 and X have the above meanings.
Patent ES-335785-A1 (ES)
Title: Skin disinfectant
IPC: C11D3/48
Filed: 1967-01-18
Abstract: Cleansing compositions comprise an aqueous alcoholic solution of 1-(3-chloroallyl)-3,5,7-triaza-1 -azoniumadamantane chloride as a disinfectant in a concentration of from 0.1 to 10% by wt. and containing from 2 to 80% by wt. of a C1- 5 aliphatic alcohol and a surface active agent. The latter may be an alkyl sulphonate, or polyglycol ether e.g. nonylphenyl-polyglycol ether. The compositions may also include quaternary ammonium compounds e.g. benzalkonium chloride, glycol derivatives, aldehydes, and skin-protecting agents e.g. glycerine, sorbitol, polyvinyl pyrrolidone.ALSO:A disinfectant composition comprises an aqueous alcoholic solution of 1-(3-chloroallyl)-3,5,7-triaza-1-azoniumadamantane chloride in a concentration of from 0.1 to 10% by wt. and containing from 2 to 80% by wt. of a C1-5 aliphatic alcohol. The composition may also include surface active agents, quaternary ammonium compounds, e.g. benzalkonium chloride, glycol derivatives, aldehydes, and skin protecting agents, e.g. glycerine, sorbitol, polyvinyl pyrrolidone.
Patent ES-336085-A1 (ES)
Title: Apparatus for the continuous separation of solids from a liquid flowing in a conduit
IPC: B01D35/02
Filed: 1967-01-26
Abstract: A filter, used to exclude mussels from cooling water intakes in seaside steam power plants, comprises a conical screen 2 located in a pipe 1 and a toroidal chamber 5 opening into pipe 1 just upstream of where screen 2 joins the pipe wall, chamber 5 having two tangential inlets and an oppositely disposed tangential outlet whereby wash water flows into the chamber and sweeps solids therefrom. Vanes 9 may support the apex of screen 2 and impart rotation to the main stream to urge solids centrifugally into chamber 5. Tangential nozzles could deliver additional water into pipe 1 to impart rotation upstream of screen 2. Screen 2 may be cleaned by closing an upstream valve arid using wash water flow in chamber 5 to rotate whole mass of water outside screen 2.
Patent ES-338955-A1 (ES)
Title: Moderator tank for pressure tube reactor
IPC: G21C13/087
Filed: 1967-04-06
Abstract: A nuclear reactor liquid moderator calandria tank comprises end walls 14b through which pass the pressure tubes 18b, rigid top plate 10b and the flexible side wall 12b. The tubes 20b accommodate the control rods 22b. The tank may be suspended by tie rods engaging the stubs 24b. Flexible elements 26b and 28 connect the side and end walls and the interior of 26b, 28 is gas filled to prevent buckling.
Patent ES-339181-A1 (ES)
Title: Fluid system safety device
IPC: H01R31/02
Filed: 1967-04-12
Abstract: A fluid pressure responsive switch for signalling on imbalance in the pressures existing within dual pipe-lines of a vehicle braking system comprises a shuttle 22, Fig. 1, sliding within a bore 18 communicating at each end with a fluid passageway 12, 14 each forming part of a pipe-line between a master cylinder and a slave cylinder, a switch portion 40 secured to the body portion 10 having a biased plunger extending through aperture 38a to engage the shuttle between a pair of surfaces 34a, 34b arranged to move the plunger axially within the switch portion into engagement with an electrical contact pin 58 on movement of the shuttle in either direction. The pin 58 is engaged with a connector 64 in an insulating housing 66 within a boot 71 having a ribbed end part received within the switch portion. The connector 64 is connected by a wire 68 to a warning light 70 and battery 72. Pressure failure in either passageway causes the shuttle 22 to move in the respective direction to lift the plunger 42 thereby illuminating the warning light 70. In another embodiment a protective boot (84), Fig. 2 (not shown) extends around the insulating housing and part of the switch portion.
Patent ES-348252-A1 (ES)
Title: A method of, and a device for, Determining the Isotope Content of a Uranium Component
IPC: B29C48/32
Filed: 1967-12-14
Abstract: The U 238 isotope content of a uranium component is determined by counting the #-radiation having an energy greater than a threshold, which is at least 300 kev and preferably 500 kev. A uranium sample 18 emitting [alpha], # and y radiation is in contact with a probe A comprising a silicon diode #-detector 12 insensitive to y-radiation which is contained in a #-radiation absorbing housing 14 and protected from [alpha]-radiation and light by an aluminium filter 17. The counting circuit B comprises an amplifier 26, adjustable threshold device 28, pulse shaper 30, integrator 32 and indicator 34. The integrator can be replaced by a more accurate counter if desired and the whole arrangement is calibrated against components with a known U 238 content.
Patent ES-351607-A1 (ES)
Title: Braking mechanism for linear measuring instruments
IPC: G01B3/10
Filed: 1968-03-14
Abstract: The winding drum 17 of a tape measure is pulled axially against a casing wall 25 by a circular spring 19 engaging an opposite wall and made integral with a sleeve 20 having a shoulder 21 engaging a sleeve 15 screwed on to a shaft 16 fast with the drum 17. A screw 18 of opposite hand to the thread on sleeve 15 holds the parts together, and the spring and sleeve 19, 20 are made of a self lubricating material which allows the sleeve 15 to rotate therein. In Figs.1 and 2 (not shown) the spring is cut by radial slots and is separate from its mounting sleeve.
Patent ES-352506-A1 (ES)
Title: Toy erection kit
IPC: A63H33/04
Filed: 1968-04-06
Abstract: A worm gear 1 for use in a constructional toy set is rigid with a coaxial pulley 8 and/or a pinion. In Fig. 1, a. V-pulley 8 integral with the worm 1 has a toothed 'base to the V- groove to act as a pinion meshable with a gear wheel narrow enough to pass between the side walls enough to pass between the side walls of the groove Fig. 3, not shown). In Fig. 4, a pinion 8 of larger diameter than the worm 1 can also act as a splined coupling to engage splines 13 in a stepped pulley 14 axially slidable over the worm.
Patent ES-358763-A1 (ES)
Title: Electric blasting cap having increased safety against unintentional initiation
IPC: F42B3/18
Filed: 1968-10-03
Abstract: The present invention concerns an electric blasting cap having increased safety against unintentional initiation, said blasting cap presenting a bridge wire and in contact with said bridge wire a fuse head composition which latter is surrounded by a protective tubing of dielectric material.
Patent ES-361475-A1 (ES)
Title: Pneumatic micrometric gauges
IPC: G01B13/18
Filed: 1968-12-05
Abstract: A pneumatic gauge has a plug T 1 , Fig. 1 for measuring a taper 17, or may be provided with a head having two plugs 21, 22, Fig.2 for measuring the distance between bores 19, 20, of a connecting rod. The gauge comprises a regulating pipe line 1, a measuring pipe line 2 supplied in parallel from a gas supply 3 via equal calibrated orifices 4 and 5, and outlets 6, 18 to atmosphere controlled by a diaphragm 9 operating needles 7, 7A connected to a measuring instrument M, the diaphragm movement being as a result of the differential pressures in 1 and 2 and the movement of 7 being proportional with limitations to variations in (D1 - D). The plug T 1 comprises orifices 13, 14 connected in parallel and joined to the line 1, and two orifices 15, 16 also in parallel but connected to the line 2. In effect the values of h 1 , h 2 , h1 1 , h1 2 2 must not exceed d/10, where d is the diameter of orifices 13-16, so that the output of an orifice is proportional to the distance to the wall facing it and (D1 -D) does not depend on the position of core 17 in the measuring unit. In Fig.2 the distance l between the bores 19, 20 is proportional to l o , the distance between plugs 21, 22, and distances h 1 , h 2 , h1 1 , h1 2 , and the orifices 23, 26 and 24, 25 are in parallel and connected to 10 and 11 respectively in a similar arrangement to that of Fig. 1. Specification 782, 691 is referred to.
Patent ES-366700-A1 (ES)
Title: Edge restrictor in down drawn glass
IPC: C03B17/06
Filed: 1969-05-02
Abstract: In the downdrawing of glass sheet 66 by flowing glass over the top edges 62 of a forming wedge 50 to combine into a single sheet at the wedge apex 68, the amount of glass flowed over at each end is restricted as by pyramidal in wedge-shaped members 30, adjustably supported at 32, so as to produce a sheet of generally uniform thickness. The molten glass from source 54 may be flowed through orifices 56 or a pipe 52 extending through the cavity 60 or may flow into a bottom conduit (14) with openings (16) into the cavity (18).
Patent ES-369708-A1 (ES)
Title: Electromagnetic switch insensitive to position orientation
IPC: H01H50/64
Filed: 1969-07-21
Abstract: The armature 52 of an electromagnetic switch is pivotally mounted in a housing 12 so as to be substantially balanced and comprises a body portion 54 which forms a "U-shape" with two arms 56a, 56b which co-operate with the ends of a core 46, on which the relay coil 36 is mounted. The core has end projections 48a, 48b extending beneath the armature arms 56a, 56b and the coil former 38 surrounding the core has projections (42a), 42b on its flanges 40a, 40b locating the core and coil assembly within a switch housing 12 and cover 14. The housing 12 also has ribs 50 locating the core projections 48a, 48b. A third arm 58 of the armature 52 extends from the body portion 54 in the opposite direction to the arms 56a, 56b and has a contact bridge 74 coupled thereto by a spring biased pin 66. The contact bridge is guided for rectilinear movement by guides 78a, 78b, 80a, 80b, formed in the housing 12 and has ribbed contacts 82a, 82b co-operating with fixed contacts 86a, 86b mounted on terminal members 90, 92. The armature has pivot pins 60a, 60b received in seats 62a, 62b in the housing 12 and is biased by a tension coil spring 104 which may be adjusted by member 110 to change the operating current of the relay. The contact mounting and biasing spring 98 is a variable rate spring which stiffens on continued armature movement after contact engagement.