baber/WOPTO huggingface dataset:
Patent MA-43322-A1 (MA)
Title: Nouveaux peptides et combinaisons de peptides et échafaudages formés de ceux-ci destinés à être utilisés en immunothérapie contre le carcinome colorectal (crc) et d'autres cancers
Inventor: MAHR ANDREA
IPC: C07K14/47
Filed: 2016-05-04
Abstract: La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules destinés à être utilisés dans des procédés immunothérapeutiques. La présente invention concerne en particulier l’immunothérapie du cancer. La présente invention concerne en outre des épitopes peptidiques de cellules t associés à une tumeur, seuls ou combinés à d'autres peptides associés à une tumeur, qui peuvent par exemple servir de principes actifs pharmaceutiques de compositions vaccinales qui stimulent des réponses immunitaires antitumorales, ou pour stimuler des cellules t ex vivo et les transférer dans des patients. Des peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou des peptides tels quels, peuvent également être des cibles d'anticorps, des récepteurs de cellules t solubles et d'autres molécules de liaison.
Patent MA-54669-A1 (MA)
Title: Boîte à parois obliques pour produits horticoles.
Inventor: ALEJANDRO FERNANDEZ PEREZ
IPC: B65D21/02
Filed: 2021-10-14
Abstract: Boîte à parois obliques pour produits horticoles, sur laquelle est définie un secteur central rectangulaire servant de fond (1), des bords duquel émergent au travers de lignes de pliage (2-2’) les joues (3) et panneaux frontaux (4) correspondants, en se prolongeant latéralement les panneaux frontaux en rabats (5) de montage pour la boîte, rabattables à partir de lignes de pli (6), où les joues (3) comme les panneaux frontaux (4) présentent une configuration trapézoïdale isocèle qui, en situation de montage, adoptent une disposition inclinée vers l’intérieur de la boîte, en déterminant une ouverture de plus petite taille que le fond de la boîte.
Patent UY-23712-A1 (UY)
Inventor: BERTA NORBERT I
IPC: A23G3/20
Filed: 1994-01-12
Abstract: The present invention is directed to an apparatus for coating a product (10) such as a medicament in the shape of a tablet. The apparatus includes a plurality of plates (50) for receiving and retaining the products and means for advancing the plates on a conveyor to various processing stations. At a dipping station, a dipping means lowers and raises at least one plate into a first coating tank (120) for coating at least a portion of the product. At a rotating station, a rotation means (70) rotates one of the plates containing the product for spreading the coating on the product. After rotation, a first elevator (302) transfers the plates from the conveyor (90) to a dryer (300) disposed above the conveyor. A second elevator (304) transfers the plates from the dryer back to the conveyor for further processing. The dryer includes complementary acting pusher bars (332) for transporting a plurality of plates horizontally along a plurality of vertically spaced guides. The plates are transported upward to traverse the guides through a first section of the dryer and downward through a second section of the dryer by the combined action of the first and second elevators and a mid-elevator (322). Several embodiments for the elevator are disclosed which include a lift bar mechanism (354), a continuous chain mechanism (376) and a lift rod system (400). <IMAGE>
Patent UY-27959-A1 (UY)
Title: Nuevos agonistas ppar alfa y ppar gama
Inventor: BINGGELI ALFRED
IPC: C07D277/24
Filed: 2003-08-27
Abstract: La presente invención se refiere a compuestos de fórmula (I) en donde R1 a R10, X, Y y n son tal como se han definido en la descripción y las reivindicaciones, y las sales y ésteres farmacéuticamente aceptables de los mismos. Los compuestos son útiles para el tratamiento de enfermedades tales como la diabetes.
Patent UY-28401-A1 (UY)
Title: Metabolito
Inventor: GOLDSTEIN JEFFREY M
IPC: A61P25/18
Filed: 2004-07-02
Abstract: Un método para tratar ansiedad, agitación, hostilidad, pánico, trastornos alimenticios, síntomas afectivos, síntomas relacionados con el humor, síntomas psicóticos negativos y positivos comúnmente asociados a esquizofrenia, demencia, ansiedad, depresión, trastornos del humor, trastornos bipolares, manía bipolar, depresión bipolar, trastornos cognitivos y trastornos neurodegenerativos que comprende administrar una cantidad eficaz de Fórmula I o su sal farmacéuticamente aceptable. En otro aspecto, la invención proporciona una composición farmacéutica que comprende una cantidad eficaz de Fórmula I o su sal farmacéuticamente aceptable y al menos un portador o diluyente farmacéuticacmente aceptable.
Patent UY-30479-A1 (UY)
Title: Moduladores de benzofuro- y benzotienopirimidina del receptor de histamina h4
Inventor: SAVALL BRAD
IPC: A61P11/06
Filed: 2007-07-11
Abstract: Se describen compuestos de benzofuro- y benzotienopirimidina que son utiles como moduladores del receptor de H4. Dichos compuestos se pueden usar en composiciones farmacéuticas y métodos para el tratamiento de estados patologicos, trastornos y afecciones mediadas por la actividad del receptor de H4, tales como alergia, asma, enfermedades autoinmunes y prurito.
Patent ES-148172-A1 (ES)
Title: PROCEDIMIENTO PARA LA DISOCIACIoN DE LAS GRASAS
IPC: C11C1/04
Filed: 1940-03-15
Abstract: Procedimiento para la disociación de las grasascaracterizado porque la reacción es efectuada haciendo pasar de un modo continuo una emulsión de agua y grasa a través de un tubo en el que se mantiene una presión elevada y una temperatura elevada.
Patent ES-150014-A1 (ES)
Title: MECANISMO DE EMBRAGUE PARA VEHiCULOS AUTOMOTORES
Filed: 1940-07-20
Abstract: Un mecanismo de embrague para vehículos automotoresen el que con la dirección de las ruedas delanteras se embraga el accionamiento de las ruedas traseras y al marchar sobre terreno desigual se acopla el accionamiento de las ruedas delanteras emoragando un engranaje reductorcaracterizado por una palanca de mano (34) que se una de tal manera con el engranaje reductor (8) y con el accionamiento (10) de las ruedas delanterasque ambas transmisiones se embragan y desembragan simultáneamente.
Patent ES-181055-A1 (ES)
Title: MEJORAS EN O RELACIONADAS CON INSTRUMENTOS oPTICOS DE OBSERVACIoN
IPC: G02B23/18
Filed: 1947-12-20
Abstract: Mejoras en o relacionadas con instrumentos ópticos de observación, caracterizadas por estar provistas de una funda de materia que amortiguará los choques.
Patent ES-181915-A1 (ES)
Title: MEJORAS EN CIRCUITOS DE TELECOMUNICACIoN PARA SELECTORES DE PRUEBAS
Filed: 1948-01-29
Abstract: Mejoras en circuitos de telecomunicación para hacer una segunda prueba de una conexión hecha por una escobilla de prueba de un selector a uno de los contactos de selector incluyendo medios de polarización adaptados para proveer voltajes distintos en los respectivos contactos del selector, medios de voltajes de etapas adaptados para proveer una pluralidad de voltajes distintos consecutivamente durante un intervalo de tiempo relativamente corto, medios de conectar el alabe de prueba del selector a unos de los electrodos, medios para conectar las potencialidades suministradas por los medios de voltaje al otro electrodo, el circuito de comparación de voltaje incluyendo medios de circuito adaptados para hacerse conductivos cuando existe una relación predeterminada de voltaje entre los mencionados dos electrodos.
Patent ES-182559-A1 (ES)
Title: MEJORAS EN SISTEMAS DE CONMUTACIoN
Filed: 1948-02-21
Abstract: Mejoras en sistemas de comunicación en los que un método de modular un tren de impulsos comprende la modulación, a una característica dada, de los impulsos impares de dicho tren con una energía de señal dada, y la modulación, a la misma característica, de los impulsos pares de dicho tren con una energía de señal dada defasada 180º de la energía aplicada a dichos impulsos impares.
Patent ES-183897-A1 (ES)
Title: PERFECCIONAMIENTOS EN EL MECANISMO DE PARO AUTOMáTICO, REGULABLE A VOLUNTAD, PARA MáQUINAS DOMÉSTICAS DE LAVAR ROPA
Filed: 1948-05-25
Abstract: Perfeccionamientos en el mecanismo de paro automático, regulable a voluntad para máquinas domésticas de lavar ropa, que están constituidas esencialmente por una rueda motriz, accionada por reducciones desde el cambio, cuya rueda presenta en una de sus caras un pivote saliente, estando dispuesto frente a esta rueda, coincidiendo con su eje geométrico e independiente de la misma, un disco provisto de diversos orificios dispuestos radialmente a igual distancia del centro que el pivote de al rueda, y de diámetro igual al de este pivote, estando el referido disco montado sobre un eje deslizable sobre su cojinete, que presenta un extremo saliente al exterior de la caja, en el que va dispuesto un botón de mando, y estando montado entre el disco y el cojinete un muelle helicoidal que tiende siempre a acercar el disco hacia la rueda provista del pivote, realizándose el acoplamiento a voluntad, entre el disco y la rueda mediante la introducción del pivote de ésta con alguno de los orificios de aquel,presentando éste en su periferia un diente que al llegar al final de su recorrido acciona una palanca, la cual actúa sobre un interruptor de paro de la máquina.
Patent ES-186047-A1 (ES)
Title: PROCEDIMIENTO PARA OBTENER, SOBRE TEJIDOS Y MATERIAS TEXTILES, UN EFECTO HIDRoFOGORESISTENTE AL LAVADO
Filed: 1948-11-24
Abstract: Procedimiento para obtener sobre tejidos y materias textiles un efecto hidrófugo resistente al lavado caracterizándose porque se condensa en medio ácido con un alcohol monovalente que encierre un número de átomos de carbono superior a diez de preferencia de C15 a C20 un producto resultante de la condensación de una amida de ácido di- o policarbónico sucesivamente con el glioxal y con el formaldelhido obtenido segun el procedimiento descrito en la solicitud de patente española depositada con esta misma fecha por procedimiento para la obtención de productos de condensación acuosolubles destinados al tratamiento de textiles siendo tal la cantidad de alcohol utilizada que una parte tan solo de los grupos metilol presentes se eterifiquen.
Patent ES-193565-A1 (ES)
Title: UN PROCEDIMIENTO DE OBTENCIoN DE UN PRODUCTO PARA GRABACIoN DE SENALES LUMINOSAS VISIBLES EN LA OSCURIDAD
Filed: 1950-06-22
Abstract: Un procedimiento de obtención de un producto para grabación de señales luminosas en la oscuridad caracterizado porque en un crisol adecuado se calienta hasta la incandescencia formándose una amasa compacta compuesta por 100 partes de Valvas cacinadas con 100 partes de Ca Anhidro con ClNo 25 partes y por último con 60 a 100 partes de S y siendo expuesto a la acción de una luz intensa consiguiéndose una perfecta luminosidad en la oscuridad. Incorporando 6 a 7 % de Sulfuro de Bario recien calcinado se obtiene una fosforescencia verdosa Con sulfuro de estroncio se logra una luminosidad rojiza.
Patent ES-199195-A1 (ES)
Title: MáQUINA AUTOMáTICA PARA LA FABRICACIoN DE FUNDAS DE PAJA PARA BOTELLAS
Filed: 1951-08-11
Abstract: Una máquina automática para la fabricación de fundas de paja para botellas caracterizada porque su mecanismo de alimentación está constituído por una serie de cadenas sin-fin provistas de dientes para arrastre de paja y dispuestas paralelamente y accionadas por las correspondientes ruedas de cadenas todas ellas adscritas a un mismo eje que en uno de sus extremos lleva montada una rueda de trinqeute sobre la que actúan dos uñas que están fijadas convenienemente y en posición invertida la una con respecto a la otra sobre una biela cuya cabeza inferior va acoplada en una excéntrica (de excentricidad regulable) que va fijada al mismo árbol que lleva adscritas las poleas origen del movimiento las cuales uñas actúan alternativamente sobre la rueda trinquete según suba o baje la biela de forma tal que el movimiento giratorio de dicha rueda trinquete es contínuo mientras que la máquina está en marcha.
Patent ES-267422-A1 (ES)
Title: Polymers of unsaturated halogenated ethers having a highly stereoregular structure and process for preparing the same
IPC: C08F16/24
Filed: 1961-05-16
Abstract: Monomers of formula X-CH=CH-OR where X is halogen and R is an aliphatic, cycloaliphatic or aromatic group containing up to 10 carbon atoms may be polymerized to high molecular weight polymers having a steric regularity of structure in the presence of a catalyst of formula MeX1nYm [Z]p in which Me is an element belonging to Group II, III, IV or V of the Mendel<\>eeff Periodic Table, X1 is a halogen, Y is an alkyl, alkoxy, acyloxy, aryl, aryloxy, aralkyl, cycloalkyl or cycloalkoxy group, Z is a Lewis base, m and n are O or an integer and m+n is the valency of Me and p is O or an integer. Specified ethers include chlorovinyl methyl, ethyl, isopropyl, butyl, isobutyl, cyclohexyl and benzyl ethers bromovinyl methyl, ethyl, isobutyl, tolyl, cyclohexyl and phenyl ethers and iodovinyl methyl and ethyl ethers which may be in the cis or trans forms. Polymerization may be effected in an inert liquid medium, e.g. toluene, and specified catalysts include aluminium trialkyls dialkyl aluminium halides such as diethyl aluminium chloride alkyl aluminium dihalides boron trifluoride etherate titanium, zirconium or vanadium dihalogen dialkoxides titanium, zirconium or vanadium dihalogen diacetates titanium dihalo dicyclopentadienyls and their complexes with alkyl aluminium compounds, alkyl aluminium halides and aluminium trichloride. The products are said to have threo-di-isotactic and erithro-di-isotactic structures. They may be used in the manufacture of shaped articles such as films, fibres and filaments which may be oriented by stretching. Specification 928,155 is referred to.
Patent ES-269543-A1 (ES)
Title: Process of producing cis-1,4 polybutadiene with a 3-component catalyst
IPC: C08F136/06
Filed: 1961-08-03
Abstract: A process for polymerizing butadiene-1,3 comprises contacting butadiene-1,3 under polymerization conditions with a catalyst selected from (1) a catalyst comprising (a) a compound of formula RnM where R is alkyl, cycloalkyl, aryl, aralkyl or alkaryl, M is aluminium, gallium, indium or thallium and n is the valence of the metal M, (b) a titanium halide of formula TiX4 where X is chlorine or bromine, and (c) an inorganic iodide of formula M1Ix where M1 is beryllium, zinc, cadmium, aluminium, gallium, indium, thallium, silicon, germanium, tin, lead, phosphorus, arsenic or bismuth and x is 2 to 5 and (2) a catalyst comprising (a1) a compound RnM as defined above, (b1) titanium tetraiodide and (c1) an inorganic halide of formula M11Xy where M11 is aluminium, gallium, indium, thallium, germanium, tin, phosphorus, antimony, arsenic or bismuth, X is chlorine or bromine and y is 2 to 5. The process may be effected batchwise or continuously, in the solid phase or in the presence of diluents, e.g. benzene, toluene, xylene, ethylbenzene, propane, butane, pentane, isopentane, hexane, isohexane, isooctane, decane, cyclohexane, methylcyclohexane, styrene, butene-1, butene-2, vinyl halides, trichloroethylene, chlorobenzene and chloronaphthalene. Specified organometallic compounds are trimethyl, triethyl, triisobutyl, tri-n-dodecyl, tricyclopentyl, triphenyl, tri-p-tolyl and tribenzyl aluminium. Many suitable titanium and inorganic halides are specified and examples describe the polymerization of butadiene in the presence of toluene and catalysts comprising triisobutyl aluminium and titanium tetrachloride with (I) antimony triiodide and (II and III) aluminium triiodide triisobutyl aluminium and titanium tetraiodide with (IV) antimony trichloride, (V) phosphorus trichloride, (VI) stannic chloride and (VII) aluminium trichloride. The products may be purified by steam stripping, the catalysts inactivated by adding ethyl alcohol or isopropyl alcohol, and the polymer stabilized by the addition of an antioxidant, e.g. phenylbeta-naphthylamine or 2,21-methylene-bis(4-methyl-6-tert. butylphenol). The products have a predominantly cis-1,4 configuration and may be compounded with fillers, other polymers, e.g. natural rubber and polyethylene, and conventional vulcanizing ingredients. They may be used in the manufacture of tyres and gaskets.
Patent ES-295262-A1 (ES)
Title: Diachronous electromagnetic coupling
IPC: H02K49/00
Filed: 1964-01-13
Abstract: A coupling having an inductor driving member, comprising at least one annular permanent magnet with interdigitated polepieces, which co-operates with a cylindrical secondary driven member having a short-circuited winding and cooling fins on its outer periphery. The rotating inductor member comprises two permanent magnet rings 13, 16 polarized as shown, mounted on hub 18 with pole rings 12, 15 attached thereto to form an interdigitated pole structure with triangular or rectangular polepieces 11, 14. Co-operating with the inductor is secondary member 3 which is generally cylindrical in shape and carries squirrel-cage winding 2 and is provided with cooling fins 1 and output gear 5. A control coil 17 is mounted on hub 18 and supplied with D.C. to produce a variable magnetic field which combines with the permanent magnet field to vary the slip of the coupling. In a modification a single permanent magnet may be used and the control coil omitted when the coupling is used as a torque damper. In other applications the inductor member is axially movable to a disengaged position where it is enclosed by a ferromagnetic cylinder to prevent demagnetization. As described, two inductor members may be movable in equal and opposite axial directions to provide the clutch action in a vehicle drive and the control coils differentially energized to give a differential action at the road wheels. A further modification shows each inductor co-operating with either one of two secondary members which have different output gears to give a change-speed gear with both clutch and differential action.
Patent ES-338815-A1 (ES)
Title: Apparatus for withdrawing sheets one by one from the bottom of a stack of sheets
IPC: B65H3/12
Filed: 1967-03-18
Abstract: Sheets are fed from a stack 11, Fig. 3, by a reciprocating member 8, 9, Figs. 2 and 3, having suction ports 15 lying in grooves 14 extending from the front of the member, which engages the bottom sheet and moves it beneath a stop plate 12 having a chamfered lower edge, air being blown from nozzles 19 into the grooves to prevent double feed.
Patent ES-346951-A1 (ES)
Title: Process for the manufacture of fluorinated aliphatic hydrocarbon compounds
IPC: B01J27/06
Filed: 1967-11-09
Abstract: C 1-4 fluorinated aliphatic hydrocarbons are obtained in a halogen-exchange process in which a halogenated saturated C 1-4 aliphatic hydrocarbon, which contains the grouping wherein X is a chlorine or bromine atom, or a mixture of such a halogenated hydrocarbon wherein X is a fluorine, chlorine or bromine, with at leact one fluorine-free halogenated saturated C 1-4 aliphatic hydrocarbon which contains the grouping wherein each of X and Y is a chlorine or bromine atom, is contacted at 20 to 500 C. with a catalyst which has been obtained by reacting a hydrated oxide of CrIII with hydrogen fluoride at 150 to 600 C. C 1-4 fluorine-free halogenated hydrocarbons may also be obtained by the above process (e.g. chloroform and carbon tetrachloride).
Patent ES-356604-A1 (ES)
Title: Apparatus for lifting and forwarding tree-length logs
IPC: B60P3/41
Filed: 1968-07-29
Abstract: A platform 18, rotatably mounted about a vertical axis 30 on the chassis of an endless track vehicle, is provided with a cab 20, timber supports 106 and luffing booms 34 supporting a fork and clamp device. Each boom consists of articulated sections 36, 38 and pivotally supports a curved fork member 68 on which clamp arms 94 are pivotally supported. In addition to boom-luffing rams (not shown), rams 52, 78, 98 are provided between the boom sections 36, 38, the boom sections 38 and the fork member, and the fork member and clamp arms, respectively. In operation, with the platform and fork member in the position shown, the vehicle is driven to engage the fork member beneath a transverse stack of timber. After operation of the clamp arms, the boom is folded to bring the timber over the supports 106, Fig. 2 (not shown). The platform is then rotated through 90 degrees so that the timber extends longitudinally of the vehicle to facilitate transportation.
Patent ES-364199-A1 (ES)
Title: An improved u-shaped metal joist and assemblies obtained therefrom
IPC: E04C3/32
Filed: 1969-02-27
Abstract: A joist of trapezial shape and U-shape transverse section has plates 3 at each end of its longer side and contains holes 4, 5. End plates 3 are each half the length of the shorter side of the trapesium. Members (6, Fig. 4, not shown) space the webs of two joists. Joists may support shuttering (10, Fig. 5, not shown).
Patent ES-367304-A1 (ES)
Title: Method for the production of humic acids, humates, and of compositions wherein they are contained
IPC: C05F11/00
Filed: 1969-05-16
Abstract: Process for the preparation of humic acids and salts thereof by successive steps of fermentation of garbage and agricultural byproducts, under selected, controlled, temperature, time, and aeration conditions.
Patent ES-373698-A1 (ES)
Title: Process for preparation of 1-h-imidazo (4,5-b)pyrazin-2-ones
IPC: C07D487/04
Filed: 1969-11-19
Abstract: Novel 3,5 - diamino - 6 - chloropyrazinohydroxamic acid derivatives of the general formula wherein R is a hydrogen atom or a C 2-5 alkanoyl, benzoyl phenyl-C 2-5 alkanoyl, C 1-3 alkylsulphonyl, phenylsulphonyl or C 1-3 alkylphenylsulphonyl group, R1 is a hydrogen atom or a C 3-7 cycloalkyl, phenyl, C 2-5 alkenyl or C 1-6 alkyl group or a C 1-6 alkyl group substituted by a C 1-3 alkoxy, pyridyl, phenyl, halophenyl or amino group, the amino group being a N- attached saturated heterocyclic residue having 5 or 6 ring members and optionally having one further heteroatom of O or N apart from the N atom that it is attached by, or having the formula -NR5R6, in which R5 is a hydrogen atom or a C 1-5 alkyl, acetyl or propionyl group and R6 is a hydrogen atom or a C 1-5 alkyl group and R2 is a hydrogen atom or a C 1-3 alkyl group or R1R2N is a nitrogen-attached saturated heterocyclic residue having 5 or 6 ring members and optionally having one further heteroatom of O or N apart from the N atom that it is attached by, are prepared by treatment of an N - t - butyl - 3 - methyl - 3 - (3,5 - diamino - 6 - chloropyrazinoyloxy)-acrylamide of the general formula with hydroxylamine and optional reaction of the resulting 3,5 - diamino - 6 - chloropyrazinohydroxamic acid of the first general formula above wherein R is a hydrogen atom with an acyl chloride of the general formula RCl and may be heated at or above their melting points for 15 minutes or maintained in a basic or neutral aqueous solution at 25-100 C. for from 30 minutes to 2 hrs., followed by acidification to pH 4, to form anti-hypertensive 5- amino - 6 - chloro - 1H - imidazo[4,5 - 6]pyrazin- 2-ones of the general formula N t - Butyl - 3 - methyl - 3 - (3,5 - diamino - 6- chloropyrazinoylozy)-acrylamides of the second general formula above are prepared by reaction of an alkyl 3-amino-5,6-dichloropyrazinoate with ammonia or an amine of the general formula R1R 2 NH, saponification of the resulting alkyl 3 - amino - 5 - R1R2N- 6 - chloropyrazinoate and treatment of the resulting 3-amino-5-R1R2N-6- chloropyrazinoic acid with N-t-butyl-5-methylisoxazolium perchlorate.
Patent ES-375523-A1 (ES)
Title: Hydrostatic button bearings for pumps and motors
IPC: F04B1/20
Filed: 1970-01-16
Abstract: In axial-piston, hydraulic pumps and motors, the thrust loadings of the pistons on their bearing supports vary proportionally to pressures in the unit and also circumferentially around the bearing supports. By employing hydrostatic button bearings pressurized in "sets" around the bearing support with at least one set pressurized with the unit's inlet pressure and another "set" pressurized by the unit's outlet pressure, improved bearing performance is achieved. Also, certain surface configuration forming the sills and recesses of the individual buttons can enhance bearing performance.