baber/WOPTO huggingface dataset:
Patent ES-2340112-T3 (ES)
Inventor: UMANA PABLO DR
IPC: A61P35/00
Filed: 1999-04-20
Granted: 2010-05-28
Abstract: The present invention provides a method for generating a host cell that produces a recombinant antibody with enhanced Fc-mediated cellular cytotoxicity, comprising: providing a host cell that is capable of expressing a recombinant antibody comprising an IgG Fc region containing N-linked oligosaccharides and genetically modifying the host cell to alter the glycosylation pattern of the antibody; wherein said recombinant antibody has an increased proportion of GlcNAc residues in the Fc region relative to the proportion of fucose residues and has increased Fc-mediated cellular cytotoxicity compared to the corresponding antibody produced by the same host cell that has not been genetically modified. The present invention also provides a method for producing a protein compound having enhanced Fc-mediated cellular cytotoxicity in a host cell. The present invention further provides a glycosylation engineered host cell that expresses a recombinant antibody comprising an IgG Fc region containing N-linked oligosaccharides, wherein said host cell has been genetically modified to regulate the expression of at least one nucleic acid encoding a glycoprotein modifying enzyme, and wherein said antibody has increased ADCC.
Patent ES-2356117-T3 (ES)
Title: Antígeno tumoral útil en el diagnóstico y la terapia de cáncer de colon y de próstata.
Inventor: AFAR DANIEL
IPC: C07K14/00
Filed: 1999-06-01
Granted: 2011-04-05
Abstract: Una proteína 20P1F12/TMPRSS2 aislada que comprende la secuencia de aminoácidos mostrada en la FIG. 1.
Patent ES-2212577-T3 (ES)
Inventor: AIZAWA KATSUO TOKYO MEDICAL CO
IPC: C07D487/22
Filed: 1999-07-12
Granted: 2004-07-16
Abstract: Novel X-ray intercepting gold complexes of mono-L-aspartyl (or mono-L-glutamyl)chlorin c6, and salts thereof, which can cause lesions of tumors, solid cancers or arteriosclerosis to be sharply imaged by radiography and enable the therapy of the lesions by X-ray irradiation. Similar platinum complexes can be also prepared in similar manners.
Patent ES-2171332-T3 (ES)
Title: Procedimiento continuo para la obtencion de poliamidas a partir de aminonitrilos.
Inventor: MOHRSCHLADT RALF
IPC: C08G69/08
Filed: 1999-01-29
Granted: 2002-09-01
Abstract: Procedimiento continuo para la obtención de una poliamida mediante reacción de al menos un aminonitrilo con agua, que comprende las siguientes etapas: (1) reacción de al menos un aminonitrilo con agua en proporción molar 1 : 1 a 1 : 10, a una temperatura de 90 a 400ºC y una presión de 0,1 a 15 x 106 Pa en un tubo de circulación, que contiene cuerpos de relleno de un catalizador ácido de Brönsted, seleccionados a partir de cuerpos de relleno de beta-zeolita, silicato laminar o dióxido de titanio, y cuerpos de relleno metálicos, estando apilados alternantemente en el tubo de circulación los cuerpos de relleno de un catalizador ácido de Brönsted, seleccionados a partir de cuerpos de relleno de beta-zeolita, silicato laminar o dióxido de titanio, y los cuerpos de relleno metálicos, obteniéndose una mezcla de reacción, (2) reacción adicional de la mezcla de reacción a una temperatura de 150 a 400ºC y una presión que es menor que la presión en la etapa 1, seleccionándose la temperatura y la presión de manera que se obtiene una primera fase gaseosa y una primera fase líquida o una primera fase sólida, o una mezcla constituida por la primera fase sólida y la primera fase líquida, y separándose la primera fase gaseosa de la primera fase líquida o la primera fase sólida, o de la mezcla constituida por la primera fase líquida y la primera fase sólida, y (3) mezclado de la primera fase líquida o la primera fase sólida, o de la mezcla constituida por la primera fase líquida y la primera fase sólida, con una fase gaseosa o líquida que contiene agua, a una temperatura de 150 a 370ºC, y una presión de 0,1 a 30 x 106 Pa, obteniéndose una mezcla de productos.
Patent ES-2291037-T3 (ES)
Inventor: PELTZ STUART
IPC: C12N9/90
Filed: 1999-07-22
Granted: 2008-02-16
Abstract: This invention provides a method of modulating translation termination efficiency of mRNA and/or promoting degradation of abberant transcripts. Also, this invention provides a method of screening for a drug active involved in enhancing translation termination and a method for identifying a disease state involving defective the protein complex. This invention provides a purified complex comprising an amount of MTT1, human Upf1p, a peptidyl eucaryotic release factor 1 (eRF1) and a peptidyl eucaryotic release factor 3 (eRF3) effective to modulate translation termination. Further, this invention provides an expression vector which comprises a nucleic acid encoding operably linked to a regulatory element, as well as an antibody which binds to the complex. This invention provides an agent which inhibits or modulates the binding of MTT1 to eRF3. The agent may inhibit or facilitate the binding of MTT1 to eRF3.
Patent ES-2241351-T3 (ES)
Title: Dispositivo para la union articulada de una hoja de limpiaparabrisas para cristales de automoviles con un brazo de limpiaparabrisas.
Inventor: DE BLOCK PETER
IPC: B60S1/38
Filed: 1999-10-23
Granted: 2005-10-16
Abstract: Dispositivo para la unión articulada de una hoja de limpiaparabrisas (10) para cristales (24) de automóviles con un brazo de limpiaparabrisas (12) guiado en el automóvil, que está dispuesto móvil entre posiciones de inversión, y que está provisto en su sección extrema libre con un bulón de articulación (16), que se extiende esencialmente en la dirección del movimiento (18), para la conexión de la hoja de limpiaparabrisas que se puede aplicar con un listón de limpiaparabrisas (20), de goma elástica, extendido alargado, en el cristal (24) y la hoja de limpiaparabrisas (10) extendida alargada comprende un elemento de soporte extendido alargado, del tipo de banda, elástico de resorte, en el que está dispuesto en un lado inferior el listón de limpiaparabrisas (20) y en la superficie superior de banda del elemento de soporte, que está alejada del cristal, está dispuesto un elemento de acoplamiento (38) con el cojinete de bulón de articulación (48) y está retenido a través de medios de retención (50) en el elemento de soporte, presentando el elemento de acoplamiento medios para asegurar la hoja de limpiaparabrisas en el bulón de articulación (16) guiado en el cojinete, caracterizado porque el elemento de soporte se proyecta en sus dos lados longitudinales con tiras marginales (30) al menos por secciones sobre los lados longitudinales del listón de limpiaparabrisas (20) y el elemento de acoplamiento (38) está conectado a través de los medios de retención (50) con las tiras marginales (30) del elemento de soporte y porque, además, el elemento de acoplamiento (38) está separado en un plano que está dispuesto al menos aproximadamente paralelo al cristal (24), porque el plano de separación (66, 68) corta el cojinete del bulón de articulación (48) y porque las dos mitades del elemento de acoplamiento (40, 42) están unidas entre sí de forma desprendible.
Patent ES-2193770-T3 (ES)
Title: Anillo de sincronizacion fabriado sin arranque de virutas con superficies de friccion estructuradas.
Inventor: SCHWUGER JOSEF
IPC: F16D23/02
Filed: 1999-11-26
Granted: 2003-11-01
Abstract: Anillo de sincronización (1, 8, 11, 13, 17, 18, 22, 24) fabricado sin arranque de virutas para una instalación de sincronización de una transmisión de automóvil - con un cuerpo de anillo (2) formado de chapa y configurado esencialmente cónico, - con una superficie envolvente exterior (4, 9, 24b) que se extiende cónicamente con respecto al eje medio longitudinal del cuerpo de anillo (2) y - con una superficie envolvente interior (7, 19, 24a) que se extiende cónicamente con respecto al eje medio longitudinal del cuerpo de anillo (2), donde el anillo de sincronización (1, 8, 11, 13, 17, 18, 22, 24) presenta al menos en una de las superficies envolventes (4, 7, 9, 19, 24a, 24b) mencionadas una superficie de fricción (5, 9a, 11a, 13a, 17a, 19a, 26, 27) y la superficie de fricción (5, 9a, 11a, 13a, 17a, 19a, 26, 27) está provista con al menos una ranura de aceite (6, 10, 12, 14, 15, 20, 25).
Patent ES-2200586-T3 (ES)
Title: Metodo para la preparacion de particulas de almidon.
Inventor: VAN SOEST JEROEN JOHANNES GERA
IPC: C08B30/14
Filed: 1999-12-29
Granted: 2004-03-01
Abstract: Un método para la preparación de partículas de almidón en un sistema de dos fases, método que comprende las siguientes etapas: (a) preparar una primera fase, que comprende una dispersión de almidón en agua; (b) i) dispersar o emulsionar en la primera fase una segunda fase, que es una fase hidrófoba, de modo que se obtiene una emulsión de aceite en agua; ii) invertir la emulsión de aceite en agua en una emulsión de agua en aceite; (c) reticular el almidón presente en la primera fase; y (d) separar las partículas de almidón así formadas.
Patent PL-1510168-T3 (PL)
Title: Wash arm arrangement for a dishwasher
Inventor: HAEGERMARCK ANDERS
IPC: A47L15/23
Filed: 2004-08-24
Abstract: This invention relates to a wash arm arrangement for a dishwasher comprising a treatment chamber (11) having one or several freely rotating support arms (16) that are provided with one or several freely rotating spray arms (20) through which liquid is distributed to the dish in the treatment chamber (11). All the movement of the support arm (16) is created as reaction forces and/or moments from the spray out of the spray arm (20).
Patent PL-1694576-T3 (PL)
Title: A tamper-evident closure
Inventor: RAMSEY CHRISTOPHER
IPC: B65D41/34
Filed: 2004-10-26
Abstract: A tamper-evident closure (10) for a container (20) is provided. The closure (10) comprises a first portion (25) including inner (35) and outer (45) parts, and a second portion (30). The outer part (45) is movable relative to the inner part (35) from a first position in which the outer part (45) is immediately adjacent the second portion (30) to a second position in which there is an empty unobstructed gap (G) therebetween. The inner (35) and outer (45) parts are adapted to become irreversibly locked in the second position so that the outer part (45) cannot be moved back to the first position to close the gap (G). A combination of such a closure (110) with an in-bore filament (100) connectable to a container (120) is also provided.
Patent PL-1608808-T3 (PL)
Title: Verfahren zur Herstellung eines polymeren Bekleidungsstoffes
Inventor: TAYLOR JOHN ARTHUR
IPC: B29C41/34
Filed: 2004-11-20
Abstract: A garment or garment material comprising a substrate and a layer of porous coagulated foam polymeric material, wherein the outer surface of the coagulated polymeric layer has a porous surface.
Patent PL-1591334-T3 (PL)
Title: Anti-theft device on freight vehicles, especially on vehicles with sliding side panels
Inventor: PRASUHN ECKHARD
IPC: E05C3/02
Filed: 2005-04-15
Abstract: A toggle lever has a joint hook fastened to a central portal of a central support. A closing mechanism is inserted into a lock yoke and a pin is inserted into an upper bore or a lower bore to lock sliding panels together. The closing mechanism is removed from the lock yoke and the pin is removed from the bore to open the sliding panels.
Patent PL-1630117-T3 (PL)
Title: Device for severing one or a number of sheets of material at a time
Inventor: LAUWERIJSSEN JOHANNES JACOBUS MARIA
IPC: B26D7/01
Filed: 2005-06-17
Abstract: Device for severing at least one sheet of web material (12) at a time, such as paper and the like, comprising: 
- a cutting table (19) over which the web material (12) can be guided and which is provided with a longitudinal groove (60), 
- a carriage (13) mounted movably above the cutting table (19), which carriage (13) is provided on the underside with at least one wheel (16,17) for pressing the web material (12) against the cutting table (19) on either side of the longitudinal groove (60), and at least one cutting body (14,15) extending in the vicinity of the at least one wheel (16,17), 
wherein the at least one wheel (16,17)and the cutting body (14,15) are fixedly mounted relative to each other, and at least one spring means is provided so as to obtain a spring action between the cutting table (19) on the one hand and wheel (16,17) and cutting body (14,15) on the other.
Patent PL-1672454-T3 (PL)
Title: Method for testing the energy performance of an industrial unit
Inventor: DROUART CAROLINE
IPC: G05B23/02
Filed: 2005-12-07
Abstract: The method involves learning a model based on the best energy performance observed for values of a set of input variables related to the production of an industrial unit. A best configuration and best settings of an equipment are proposed in real time, to an operator, based on the settings. The settings are associated with the performance observed in the past for the current value of the set of input variables. An independent claim is also included for an industrial unit`s energy performance controlling system for implementing a method for controlling the energy performance of an industrial unit.
Patent PL-1852534-T3 (PL)
Title: Washer/dryer with additional condensing circuit
Inventor: GASTALDELLI LUCIO
IPC: D06F58/24
Filed: 2006-05-03
Abstract: A washer/dryer includes a fan (F) connected to a condensing duct (C) so as to create a stream of moist air coming from the tank (T) through an air entrance (A), as well as a load bay (B) for detergent/additives provided with water jets (W), controlled by an electrovalve, that is connected to the tank (T) through a connecting pipe and a vent pipe (V), as well as an expansion chamber (E) connected to the load bay (B) and to the condensing duct (C) through a return pipe (S). In this way, a greater condensing effectiveness is achieved thanks to the additional condensing circuit (V, B, E, S) that operates in parallel with the primary condensing circuit, resulting in a reduction of drying time and power consumption.
Patent PL-1899605-T3 (PL)
Title: Pilot valve for a coolant compressor, and coolant compressor
Inventor: AGUILAR ROJAS JOAN
IPC: F04B27/18
Filed: 2006-07-05
Abstract: A refrigerant compressor has a control valve for controlling the degree of conveyance of the refrigerant compressor by setting a drive housing pressure pC of the refrigerant compressor. A control body controls a conveying-side control line between a discharge chamber, acted upon by high pressure of the compressor, and the drive housing of the compressor, and also controls a suction-side control line between the drive housing and a suction chamber, acted upon by suction pressure of the compressor variably in a throttling and/or shutting-off manner. The control body is driven electromagnetically. To improve the refrigerating capacity and the control behavior of the refrigerating system, the control body, which can shut off both the conveying-side and the suction-side control line, is also driven by means of a pressure cell.
Patent PL-1909055-T3 (PL)
Title: Base, in particular for hunting and sport weapons
Inventor: RECKNAGEL GEORG
IPC: F41G1/387
Filed: 2007-09-11
Abstract: The base (1) has at least one fixing element on its long side, and may be of trapezoid shape, both internally and externally. The fixing element may have a lug and a clamping screw. There may be at least one internal-prism recess in the upper surface and/or at least one external-prism engaging part to serve as an extra fixing element.
Patent PL-1891974-T3 (PL)
Title: Combinations comprising antimuscarinic agents and PDE4 inhibitors
Inventor: GRAS ESCARDO JORDI
IPC: A61P11/06
Filed: 2005-05-31
Abstract: A combination which comprises (a) a PDE4 inhibitor and (b) an antagonist of M3 muscarinic receptors which is (3R)-1-phenethyl-3-(9H-xanthene-9-carbonyloxy)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid.
Patent PL-1986521-T3 (PL)
Title: Carrying system for rucksacks
Inventor: LEYENDECKER DANIEL
IPC: A45F3/04
Filed: 2007-02-16
Abstract: The invention relates to a carrying system for a rucksack with at least one accommodation container with at least two shoulder straps which connect the rucksack to a carrier, with each shoulder strap having at least two strap sections, and with each shoulder strap having at least one first releasable connecting device which connects the two strap sections to one another. The carrying system according to the invention is characterized in that a triggering device is provided which can be operated by the carrier and is connected to at least two releasable connecting devices in such a way that the connecting devices are released substantially without a time delay when the triggering device is operated.
Patent PL-2198133-T3 (PL)
Title: Particle filter assembly and method for cleaning a particle filter
Inventor: LUCKA KLAUS
IPC: F01N3/025
Filed: 2008-09-01
Abstract: Engine exhaust system for an internal combustion engine, the engine exhaust system comprising an exhaust conduit (14) connected to an engine (30), an exhaust gas return conduit (32,33) such that at least a part of the exhaust gas can be returned to the engine. The exhaust gas return conduit, at least along a part of its length, is formed with at least two flow paths (48,49). The engine exhaust system further comprises a particle filter arranged in each of the at least two flow paths and at least one cold flame vaporizer (11) in which fuel is partially oxidized in preheated air to form a cold flame gas. The at least one cold flame vaporizer is arranged in fluid communication with all the flow paths such that the cold flame gas can flow through the particle filters, whereby the cold flame gas can be used to regenerate the particle filter in at least one of the exhaust flow paths while, simultaneously, exhaust gas can flow through the other exhaust flow path or exhaust flow paths. A method for the cleaning of a particle filter is also provided.
Patent PL-2148090-T3 (PL)
Title: Locking assembly for the rotor of a wind power turbine
Inventor: PABST OTTO
IPC: F03D11/00
Filed: 2009-07-23
Abstract: A wind power turbine (1) has a fixed assembly (2, 12); a mobile assembly (4, 10, 15) fitted to the fixed assembly (2, 12) to rotate about an axis (5) with respect to the fixed assembly (2, 12); and a locking device (44) for making the mobile assembly (4, 10. 15) and the fixed assembly (2, 12) integral with each other; the locking device (44) has at least one groove (45, 46) formed on the fixed assembly (2, 12) or the mobile assembly (4, 10, 15) and coaxial with the axis (5), and angular locking means (47, 48) that can be activated to pressure engage the groove (45, 46).
Patent GR-3002728-T3 (GR)
Title: Roller door
Inventor: LUCIANO UMBERTO
IPC: E06B9/56
Filed: 1991-09-16
Abstract: A cable (10) is connected to each of the ends of the cross member (7) fixed to the free end of the flexible panel (1) of a roller door, and passes over lower fixed return pulleys (11, 12), over an upper pulley (13) which is rotatable in a vertically movable bracket (16), and is connected to a lower fixed point (15) with the interposition of a helical tensioning spring (14) working under tension. The bracket (16) is supported by a flat belt (17) or a cable wound onto the shaft (3) of the roller (2) onto which the panel (1) is wound, in the opposite sense to the sense of winding of the panel, and is subject to the action of a balancing spring (19) working under tension and serving to balance the weight of the panel. The balancing spring (19) may be replaced by a counterweight (24).
Patent GR-3003554-T3 (GR)
IPC: C07C237/26
Filed: 1992-01-09
Abstract: A process for the hydrogenation of a 6-methylene-tetracycline in the production of alpha-6-deoxytetracycline, particularly the antibiotic doxycycline, in the presence of a transition metal complex of the formula MClx(PPh3)y wherein M is preferably Cu, Co or Ni, x is 1 or 2 and y is 1-3, and a trace of rhodium either as the supported metal or as a rhodium salt, as a hydrogenation catalyst. The desired alpha-6-deoxytetracycline product is produced in high yields and stereospecificities. The process requires the use of substantially cheaper transition metal complexes and only traces of rhodium in the hydrogenation catalyst per mole of the 6-methylene tetracycline hydrogenated.
Patent GR-3005331-T3 (GR)
IPC: C12N9/04
Filed: 1992-07-31
Abstract: A reagent for the enzymatic determination of primary C1-C4 alcohols, especially methanol or ethanol, consists of alcohol oxidase, an excess of peroxidase and chromotropic acid:antipyrine as a chromogen system, in associated, lyophilized form.
Patent GR-3006759-T3 (GR)
IPC: C07H3/04
Filed: 1993-01-11
Abstract: The invention relates to pharmaceutical compositions having anti-endotoxic activity, comprising as the active component a fraction which can be isolated from lactulase syrup by means of absorption at a sulphonated polystyrene cation resin in the Ca<2><+>-form and elution with a suitable solvent. the lactulose sytup can be obtained by basic isomerisation of lactose at elevated temperature, optionally in the presence of sodiumsulphite.
Patent GR-3015469-T3 (GR)
Title: 5,11-dihydro-6H-pyrido[2,3,-b][1,4]benzodiazepin-6-ones and -thiones and their use in the prevention or treatment of AIDS.
Inventor: HARGRAVE KARL D DR
IPC: C07D471/04
Filed: 1995-03-20
Abstract: Disclosed are novel 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones and -thiones. These compounds, as well as certain known 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection.
Patent GR-3017180-T3 (GR)
Title: Peelable barrier film for vacuum skin packages and the like.
Inventor: SOLOMON BEKELE
IPC: B65D75/58
Filed: 1995-08-23
Abstract: Disclosed is a film (1) for forming vacuum skin packages which comprises a coextruded, multi-layer composite forming web comprising a gas permeable film (2) and a gas impermeable film (3) which can be manually delaminated from each other, the gas permeable film having a plurality of layers including a heat sealable, polymeric layer, and a layer comprising a linear ethylene/alpha-olefin copolymer having a density of less than 0.915 g/cc, the gas impermeable film having a plurality of layers including a barrier layer of a hydrolyzed ethylene/vinyl-acetate or vinylidene chloride copolymer the barrier layer being immediately adjacent to and in contact with the linear ethylene/alpha-olefin copolymer so that when the layers are peeled apart the barrier layer will become a first surface layer and, an outer or second surface layer of polymeric material: the heat sealable layer of the permeable film seals to the surface of the package support member with a bond strength greater than the force required to delaminate the permeable layer from the impermeable layer so that the permeable layer can be peeled from the impermeable layer leaving the package covered with a permeable layer so that oxygen can penetrate to the packaged product.
Patent GR-3018517-T3 (GR)
Title: Medical cutting device
Inventor: KURZ HEINZ
IPC: A61B17/00
Filed: 1995-12-21
Abstract: The medical cutting device (19) for producing thin cartilage discs has, in a body (11) of the device, a depression (13) which has a flat bottom surface and is used for receiving cartilage excisions. The depression (13) is open towards one end face (11.1) of the body (11) of the device. Formed in the lateral delimiting ridges (14, 15) of the depression (13), at a distance from and parallel to the bottom surface of the depression (13), is a guide slot (17) for a cutting blade, by means of which the thin cartilage discs are produced. The cartilage excision is held securely in the depression (13) by means of a cover (12) which can be centred. <IMAGE>
Patent GR-3019356-T3 (GR)
Title: Recombinant mycoplasma hyopneumoniae antigen and uses therefor
Inventor: FAULDS DARYL H
IPC: C07K14/30
Filed: 1996-03-19
Abstract: Gentically Engineered M. hyo antigen; in particular the 74.5 kDa; or 41 kDa, or 36 kDa; or 96 kDa; or 41* kDa antigen, and mutations thereof. The antigens can be used as vaccines or diagnostics.