baber/WOPTO huggingface dataset:
Patent EP-1501935-B1 (EP)
Title: Low-cost production of peptides
Inventor: KREBS JOSEPH F
IPC: C07K5/06
Filed: 2003-04-22
Granted: 2009-09-23
Abstract: The subject invention relates to a low cost method of producing peptides, including antimicrobial peptides (AMPs), by using microbes. The subject methods enable greatly improved yields of the peptide/AMP as compared to those heretofore known in the art. The subject methods also surprisingly enable the use of Pseudomonas fluorescens to produce AMPs and other peptides. There are several components of the subject invention, which can be used alone or in combination. The subject invention provides for the production of peptides/AMPs in concatemeric precursors. The subject invention also provides novel methods of assembling monomers into multimers, and of cleaving the multimers to yield active monomers. The subject invention also relates to the use of these multimers fused to carrier peptides to produce fusion proteins. Preferably, both the multimers and the fusion proteins (multimers with the carrier polypeptides) lack charge balancing. It has been surprisingly determined that it is not necessary to offset the positive charges of multiple copies of AMPs in multimeric constructs. Thus, the subject invention enables the use of a wider range of multimers and carrier peptides.
Patent EP-1468173-B1 (EP)
Inventor: ELLMER DIETMAR
IPC: F02B37/12
Filed: 2003-01-07
Granted: 2007-03-21
Abstract: L'invention concerne un procédé pour commander un surpresseur électrique (12) dans un moteur à combustion interne équipé d'un turbocompresseur à gaz d'échappement (18, 32) de sorte que ledit surpresseur électrique (12) soit mis en circuit avec le plus faible prélèvement de puissance possible. Selon l'invention, la mise en circuit du surpresseur (12) s'effectue en fonction du bilan de puissance, ledit surpresseur étant activé uniquement lorsque la puissance momentanément disponible du turbocompresseur à gaz d'échappement (18, 32) est insuffisante pour mettre à disposition la puissance nécessaire.
Patent EP-1476673-B1 (EP)
Inventor: BAUMGARTNER JOHANN
IPC: F16D66/02
Filed: 2003-02-12
Granted: 2005-09-21
Abstract: The disc brake has a brake caliper (3) cooperating with a brake disc, incorporating a pneumatically- or electrically-operated brake application device and a brake adjustment device for compensating brake pad wear, operated by an electric motor (37) with an associated control device directly integrated in the disc brake. The electric motor can be mounted on a hybrid circuit board (36) together with logic circuit and control elements (40), enclosed by a housing cover (38) secured to the brake caliper.  An Independent claim for an operating method for a disc brake is also included.
Patent EP-1493851-B1 (EP)
Inventor: SAKAMOTO GODO
IPC: D02J1/22
Filed: 2003-04-04
Granted: 2012-01-04
Abstract: A filament having excellent incision resistance includes as a primary component a polyethylene filament having a weight-average molecular weight of 300,000 or less and a ratio of a weight-average molecular weight to a number-average molecular weight (Mw/Mn) of 4.0 or less as determined in the state of a filament as well as a modulus of 500 cN/dtex or more. This filament is useful to produce a fabric excellent in incision resistance, a fibrous material for reinforcing mortar or concrete, and a rope, each of which comprises the filament. The filament can be produced by drawing a non-drawn polyolefin filament which comprises a polyethylene having a weight-average molecular weight of 60,000-600,000, a ratio of a weight-average molecular weight to a number-average molecular weight (Mw/Mn) of 4.5 or less, and a rate of birefringence (Δn) of 0.008 or more, at a temperature not higher than the α-relaxation temperature of the non-drawn filament.
Patent EP-1513575-B1 (EP)
Inventor: PERSSON JAN-OVE
IPC: A61M25/02
Filed: 2003-05-23
Granted: 2007-03-07
Abstract: The present invention concerns a plaster for attaching a trachestoma valve or the like in connection with a tracheostoma on a person's neck. The plaster comprises a socket and an annular flange, communicating with a central opening of the flange which is connected with a single-coated adhesive tape which extends radially beyond the edge of the flange. The connection includes a first annular joint at or inwardly of the outer periphery of the flange, and a second annular joint located between the outer periphery of the flange and the inner periphery of the flange spaced radially from the first annular joint. A protecting liner covers the adhesive on the tape.
Patent EP-1521910-B1 (EP)
Inventor: BROWN ROBERT
IPC: F02M37/32
Filed: 2003-07-11
Granted: 2008-12-17
Abstract: A solenoid fuel drain valve ( 2 ) comprising a valve body ( 4 ), having a drain hole ( 20 ) and an air inlet opening ( 22 ), a solenoid coil ( 10 ) and a piston, the drain hole ( 20 ) having a drain inlet ( 20 ) and a drain outlet ( 15 ); and the piston being arranged within the valve body ( 4 ) to be moveable between a closed condition, wherein the drain hole ( 20 ) and the air inlet opening ( 22 ) are sealed, and an open condition, wherein the drain hole ( 20 ) and the air inlet opening ( 22 ) are open, movement of the piston being controlled by the solenoid ( 10 ).
Patent EP-1573834-B1 (EP)
Inventor: ZAGHIB KARIM
IPC: H01M50/491
Filed: 2003-11-13
Granted: 2009-04-15
Abstract: A method of preparing an electrochemical electrode which is partially or totally covered with a film that is obtained by spreading an aqueous solution comprising a water-soluble binder over the electrode and subsequently drying same. The production cost of the electrodes thus obtained is reduced and the surface porosity thereof is associated with desirable resistance values.
Patent EP-1569829-B1 (EP)
Inventor: EGNER-WALTER BRUNO
IPC: B60S1/24
Filed: 2003-12-09
Granted: 2007-09-26
Abstract: A ball pin comprising a ball and a pin connected to the ball is characterized in that the ball is provided with a recess on its side facing away from the pin, the diameter of said recess corresponding approximately to the diameter of the pin.
Patent EP-1576011-B1 (EP)
Inventor: GURNEY AUSTIN L
IPC: A01K67/027
Filed: 2003-10-29
Granted: 2009-08-12
Abstract: The invention concerns inhibition of the production of proinflammatory cytokine Interleukin-17 (IL-17) by T cells, using an antagonist of interleukin-23 (IL-23). The invention further concerns the use of IL-23 antagonists in the treatment of inflammatory diseases characterized by the presence of elevated levels of IL-17. IL-23 antagonists include, without limitation, antibodies specifically binding to a subunit or IL-17 or an IL-17 receptor. The invention additionally concerns induction of IL-17 production by using an IL-23 agonist.
Patent EP-1529239-B1 (EP)
Inventor: DOORNKAMP CISKA
IPC: G02F1/1335
Filed: 2003-07-22
Granted: 2005-12-14
Abstract: This invention relates to a transflective liquid crystal display device, having a plurality of pixels ( 1 ), each comprising a liquid crystal layer ( 2 ) being sandwiched between a front and a back substrate ( 4, 5 ), a back light ( 10 ), a semi-transparent reflective element ( 7 ), being arranged between the back substrate ( 5 ) and the back light ( 5 ), a front polarizer ( 6 ), and a driving arrangement ( 3 ) for controlling optical properties of the liquid crystal layer ( 2 ), whereby the pixel is subdivided into a reflective pixel part ( 1 a) and a transmissive pixel part ( 1 b). According to the invention, a cholesteric layer composition ( 11, 12 ) is arranged between said liquid crystal layer ( 2 ) and the back substrate ( 5 ), said cholesteric layer composition comprising; in said reflective pixel part ( 1 a), a first cholesteric layer composition part ( 11 ) for reflecting a desired primary pixel color, and in said transmissive pixel part ( 1 b) a second cholesteric layer composition part ( 12 ) for reflecting the remaining primary colors, other than said desired primary pixel color.
Patent EP-1556020-B1 (EP)
Inventor: SVEINSSON BIRKIR
IPC: A61P17/06
Filed: 2003-08-12
Granted: 2009-02-25
Abstract: A method for treating, remedying, or preventing inflammatory skin disorders by administering a therapeutically effective dose of at least one an antagonist of a calcitonin gene-related peptide receptor in a pharmaceutically acceptable formulation. The method for treating, remedying, or preventing an inflammatory skin disorder by administering topically and to the prepsoriatic rim a therapeutically effective dose of at least one an antagonist of a calcitonin gene-related peptide receptor in a pharmaceutically acceptable formulation.
Patent EP-1544996-B1 (EP)
Inventor: ISHIZAKI HIROYUKI
IPC: H03F3/217
Filed: 2003-07-25
Granted: 2011-06-29
Abstract: デジタルアンプ（２１）は、ゲートドライブ回路（２８，２９）が出力トランジスタ（Ｑ２１～Ｑ２４）を駆動し、可変電圧電源（３０）からの電源電圧（Ｖ０）をスイッチングさせることでΔΣブロック（２２）からの１ビットデジタル信号の振幅増幅を行う。可変電圧電源（３２）は、上側ゲートドライブ回路（２８）による出力トランジスタ（Ｑ２１，Ｑ２３）の駆動電圧を、可変電圧電源（３０）からの電源電圧（Ｖ０）に下側ゲートドライブ回路（２９）に与えられる一定電圧（Ｖ１）を加算した電圧（Ｖ０＋Ｖ１）として、電源電圧（Ｖ０）に追従して変化させる。これにより、出力トランジスタ（Ｑ２１，Ｑ２３）のスイッチング動作に影響を与えることなく、駆動電圧が必要最小限の電圧になる。したがって、小ボリューム時における上側ゲートドライブ回路（２８）の消費電力を削減できる。
Patent EP-1573476-B1 (EP)
Inventor: KATOCH ATUL
IPC: G06F1/00
Filed: 2003-07-31
Granted: 2007-09-05
Abstract: An electronic data processing circuit uses current mode signalling on a communication conductor, wherein a receiver supplies current to the communication conductor to try and keep a voltage on the conductor constant and measures the current that is needed to do so. A transition coding circuit is coupled between a data source circuit and the communication conductor, for driving the communication conductor in a first state in pulses in response to transitions in the logic signal and in a second state outside the pulses. The level that is used for indicating no change is selected so the current that needs to be supplied by the receiver is smaller when no change is signalled than when a change is signalled. Preferably only a nearly zero quiescent current is needed when there is no change.
Patent EP-1537691-B1 (EP)
Title: Verfahren und einrichtung zum synchronisieren eines mobilfunkempfängers
Inventor: BECKER BURKHARD
IPC: H04B7/26
Filed: 2003-08-08
Granted: 2011-10-05
Abstract: Bei einem Verfahren zum Synchronisieren eines Mobilfunkempfängers mit einer Zeitschlitzstruktur eines von einer Basisstation erhaltenen Funksignals über das Auffinden mindestens einer bestimmten Zeitschlitzgrenze wird ein von dem Mobilfunkempfänger empfangener Datenstrom in einem Filter gefiltert. Das Filter stellt nach der Filterung eine Entscheidungsfolge (Y) von Empfangsdaten als Menge der maximal möglichen bestimmten Zeitschlitzgrenzen bereit. Die Entscheidungsfolge (Y) wird in einem zweistufigen Verfahren derart weiterverarbeitet, dass in einer ersten Verfahrensstufe eine Untermenge (Ysub) aus der von dem Filter bereitgestellten Entscheidungsfolge (Y) ausgewählt wird und danach in einer zweiten Verfahrensstufe eine zeitliche Mittelung der Elemente der genannten Untermenge (Ysub) erfolgt, als deren Ergebnis die zur Synchronisation dienende Zeitschlitzgrenze erhalten wird. Dabei erfolgt die Auswahl der genannten Untermenge (Ysub) unter Ausnutzung statistischer Eigenschaften von solchen Signalabtastwerten, die zu einer Zeitschlitzgrenze gehören, und von solchen Signalabtastwerten, die nicht zu einer Zeitschlitzgrenze gehören.
Patent EP-1534091-B1 (EP)
Inventor: FOCKE HEINZ
IPC: A24C5/14
Filed: 2003-08-01
Granted: 2007-06-27
Abstract: The method involves feeding compressed air into one end of the filter cigarette (10) and measuring the air discharged from the other end. The filter cigarette is divided longitudinally into multiple test sections (22,23), and air can be separately fed into each test section and/or discharge air can be extracted.  An Independent claim is included for an apparatus for testing cigarettes.
Patent EP-1572588-B1 (EP)
Inventor: GUNNARSSON GUDMUNDUR
IPC: C01B33/187
Filed: 2003-11-27
Granted: 2011-01-26
Abstract: A process for producing from olivine precipitated silica with controlled specific surface area and high degree of purity. The process comprises adding olivine in a controlled manner to a heated mineral acid solution; after separating undissolved olivine and filtering the silica is slurried in aqueous solution to obtain a low viscosity high solid content silica slurry that can be efficiently degritted and dried with a relatively low energy consumption. The obtained silica can be in powder, bead or granule form and preferably has a specific surface area of at least about 100 m2/g.
Patent EP-1581513-B1 (EP)
Inventor: HERLIHY SHAUN LAWRENCE
IPC: C08F2/50
Filed: 2003-12-10
Granted: 2007-02-14
Abstract: Compounds of formula (I): wherein the substituents are as defined herein.
Patent EP-1556721-B1 (EP)
Inventor: CHEN WENZONG
IPC: G02B6/38
Filed: 2003-10-24
Granted: 2006-06-14
Abstract: A fiber optic connector module includes a ferrule terminated to at least one optical fiber. The ferrule has a rearwardly facing abutment surface. The ferrule is mounted within a housing which includes a forwardly facing abutment surface for engaging the rearwardly facing abutment surface on the ferrule. The forwardly facing abutment surface on the housing is convexly rounded so that the ferrule can tilt relative to the housing.
Patent EP-1469691-B1 (EP)
Inventor: MASUDA KATSUYUKI
IPC: H04M1/72433
Filed: 2004-02-13
Granted: 2007-10-10
Abstract: The invention provides a mobile phone system, which can give a desired voice message to a user of an opposite party terminal without speaking in a state that limitation to usable voice messages has been reduced, while allowing a user existing under an environment that he/she can not speak to listen to a voice from the opposite party terminal.  A mobile phone terminal (1) is provided with means (12) for transmitting a connection request of a packet switching line to the side of a network and means (11) for transmitting data corresponding to a desired voice message, while the network is provided with data/voice message converting means (4) for converting transmitted data to a voice message corresponding thereto and means for merging the converted voice message to a circuit switching line of the opposite party terminal to transmit the same.
Patent EP-1466990-B1 (EP)
Inventor: FRIEDERICH HEINRICH DR
IPC: F16B35/00
Filed: 2004-03-26
Granted: 2007-01-03
Abstract: Production of a screw made from a low-alloyed carbon steel comprises a hardening step carried out by rapid heating with a high energy transfer and subsequent quenching and limited to partial regions of the periphery of the functional tip. An independent claim is also included for a screw produced by the above process.
Patent EP-1475217-B1 (EP)
Inventor: KAWANISHI NAOYUKI
IPC: B29C59/04
Filed: 2004-05-06
Granted: 2009-04-08
Abstract: An antiglare film producing method of film production by surface embossing to polymer film (11a, 11b) is provided. The polymer film includes a support (31, 41) of triacetyl cellulose, and an anti-reflection layer (32, 44, 50, 55) overlaid thereon. An embossing roller (22) is used for surface embossing to a front surface of the support or a surface of the anti-reflection layer. In the film producing method, the embossing roller is produced according to electrodischarge machining (EDM). A surface of the embossing roller has an arithmetic average roughness Ra of 0.3-1.0 micron, and has a protruding and retreating pattern with an average cycle length RSm of 5-30 microns. <IMAGE>
Patent EP-1457234-B1 (EP)
Inventor: WHITEHURST COLIN
IPC: A61N5/06
Filed: 2001-03-20
Granted: 2010-03-17
Abstract: A therapeutic light source comprises rigid arrays of LED's (LF, LL, LR) movably connected together, and cooled by forced air convection. The output intensity of the arrays is at least 10mW/cm<2> with a spatial intensity fluctuation of 10% or less in the treatment field. The emission spectra of the LED's may be substantially limited to the range 400 to 430 nm, or 590 to 640 nm. The light source may be used for cosmetic treatment, such as skin rejuvenation, wrinkle removal and/or biostimulation. <IMAGE>
Patent EP-1528165-B1 (EP)
Inventor: ASAM DIRK
IPC: E02F9/28
Filed: 2004-08-27
Granted: 2008-07-16
Abstract: At least one tooth (14) can be inserted in its length direction into one or more tooth holders (12) in the tool. The length of the tooth protruding from the holder can be adjusted. Fixing parts are used to secure the tooth inside the holder. Clamping pins (18), screws or clamping parts such as wedges or clamping tongues are used as fixing parts. The tool comprises a shell (10) with at least one pointed tooth.
Patent EP-1541878-B1 (EP)
Inventor: HOFFMANN ARMIN
IPC: F16B7/18
Filed: 2004-12-09
Granted: 2012-02-22
Abstract: The fastening system for the fastening of a first component on the support of a mounting system has a threaded component (12) with a torque transmitting means (13), a locating element (18) for locating against one of the components, and a mating threaded component (27) engaging with the first (12). The mating threaded component has an undergrip section (31) and a locating section (30), whereby the undergrip section is located at a distance from the locating section in the direction of the fastening axis (29) and connected to the locating section via a connecting section (32). An independent claim is included for a mating threaded component for the aforesaid fastening system.
Patent EP-1604781-B1 (EP)
Inventor: WALKER ANDREW
IPC: B24B55/05
Filed: 2004-06-07
Granted: 2008-01-02
Abstract: A belt sander (2) comprising a housing (4) and having a lower sanding surface (40) and an upper sanding surface (42) opposite the first sanding is disclosed. The sander has a larger rear roller (32) driven by a motor (22), a front roller (34) of smaller diameter than the rear roller, and an endless sanding belt (38). A guard (48) is pivotable between a lowered position preventing access to the upper sanding surface and a raised position allowing access to the upper sanding surface. A handle (12) on the housing is pivotable between a first handle position adjacent the upper sanding surface and at least one second handle position further from the upper sanding surface than the first handle position.
Patent EP-1495755-B1 (EP)
Inventor: OSOWSKA-VINCENT SYLWIA
IPC: A61K38/27
Filed: 2004-07-08
Granted: 2009-10-14
Abstract: L-citrulline is used to prepare a medicament for treating disorders associated with intestinal insufficiency. ACTIVITY : Antiinflammatory; Antiulcer. MECHANISM OF ACTION : None given.
Patent EP-1543997-B1 (EP)
Inventor: COUTURIER PHILIPPE
IPC: B60B21/04
Filed: 2004-11-24
Granted: 2008-03-26
Abstract: The rim has an inner side wall (325) with a curve segment extending between two points (A 0, B 0). The point (A 0) is situated adjacent to a base of a well (314). The point (B 0) is placed at a distance greater than a predetermined distance from the point (A 0) in a projection on a principle axis. The point (B 0) is spaced axially in a direction of a connection part (13) from the point (A 0). An independent claim is also included for a wheel of a motor vehicle.
Patent EP-1544012-B1 (EP)
Inventor: DAUMAL CASTELLON MELCHOR
IPC: E05F15/16
Filed: 2004-09-28
Granted: 2008-04-02
Abstract: It is provided in a door resistant structure (21) for securing a power window device. The assembly (10) comprises a cover drum (11) and a screw (12). The drum (11) comprises a polyhedric body having a flat lower base (23) extending around a central bore (16) affecting the body of the cover drum (11) in a skirt (17,18) having a first portion (17) directed downward vertically and extending into a concave portion (18). The upper part of said cover drum (11) extends upward in a skirt (15) that is bent on itself directed downward. The screw (12) is secured inside said cover drum (11) by being pressed by the skirt (15) and the lower perimeter thereof.
Patent EP-1674194-B1 (EP)
Title: Extensible protection provided with a means for detection of wear, risk of ignition or flame and machine including such an extensible protection
Inventor: PLUESS THOMAS
IPC: B23K26/42
Filed: 2004-12-24
Granted: 2008-04-02
Abstract: The extendable shield, designed to cover a high-energy beam such as a laser on part of its trajectory between two optical elements, has its inner surface facing the beam fitted with a detector in the form of at least one conductor wire that can carry a current. The wire can be broken by a mechanical stress above a set level or by high temperature caused by the laser beam or a flame, interrupting the current passing through it and warning of shield wear or the risk of fire. The detector can be used to set off a warning signal or switch off the laser beam.
Patent EP-1590362-B1 (EP)
Inventor: BERGMANN FRANK
IPC: C01D5/14
Filed: 2004-01-28
Granted: 2007-09-19
Abstract: The present application is directed to a method for performing a bisulfite reaction to determine methylation positions in a nucleic acid, i.e. methylated and non-methylated cytosines, whereby the nucleic acid is incubated in a solution comprising the nucleic acid for a time period of 1.5 to 3.5 hours at a temperature between 70 and 90° C., whereby the concentration of bisulfite in the solution is between 3 M and 6.25 M and whereby the pH value of the solution is between 5.0 and 6.0 whereby the nucleic acid, i.e. the cytosine bases in the nucleic acid, are deaminated. Then the solution comprising the deaminated nucleic acid is desulfonated and preferably desalted. The application is further related to a solution comprising bisulfite with a certain pH and uses thereof as well as a kit comprising the solution.
Patent EP-1594369-B1 (EP)
Inventor: MAEKI MAARIT
IPC: A23L29/00
Filed: 2004-02-20
Granted: 2010-04-21
Abstract: The present invention relates to fermentation of plant-derived material with a starter comprising a lactic acid bacterium, Lactobacillus sp.96/142 isolated from sauerkraut. Said Lactobacillus strain is likely to belong to the species Lactobacilllus sakei. The lactic acid bacterium of the invention degrades glucosinolates contained in the plant material. The degradation products produced by the bacterium exhibit among other things antimicrobial properties, and may possess a health-promoting effect. The invention further relates to the use of said Lactobacillus strain in the production of exopolysaccharides applicable to improving of food structure.
Patent EP-1601874-B1 (EP)
Inventor: TAKAYAMA SHUICHI
IPC: C12N5/07
Filed: 2004-03-10
Granted: 2009-05-27
Abstract: Microfluidic devices having active features such as valves, peristaltic pumps, and mixing portions are fabricated to have a thin elastomeric membrane over the active features. The active features are activated by a tactile actuator external to the membrane, for example, a commercial Braille display. The display may be computer controlled, for example by simple text editor software, to activate individual Braille protrusions or a plurality of protrusions to actuate the active portions of the microfluidic device. Integral devices can incorporate the tactile actuators in a single device, but still external to the membrane.
Patent EP-1637112-B1 (EP)
Inventor: KATO HISASHI
IPC: A61F5/01
Filed: 2004-03-15
Granted: 2012-05-09
Abstract: 股関節に対応する位置に設けた補助動力発生装置が発生する力の脚部への伝達効率を高め、且つ身体の負担を軽減し得る歩行補助装置を提供するために、下肢の運動に補助力を与えるべく少なくとも股関節の側方に補助動力発生装置（股関節アクチュエータ１０）を備えた歩行補助装置を、補助動力発生装置を股関節の側方に固定するための腰部装具（１）と、下腿部に装着される下腿部装具（２）と、補助動力発生装置と下腿部装具とを連結する力伝達部材（連結バー２５）とを有するものとする。これにより、補助動力発生装置が発生する股関節回りのトルクが、膝よりも下方に伝達されるので、大腿部に力を直接付与する場合に比して、身体の作用点に加わる力を軽減することができる。