baber/WOPTO huggingface dataset:
Patent EA-004950-B1 (EA)
Title: Amorphous torasemide modification
Inventor: FILIC DARKO
IPC: A61P7/10
Filed: 2000-05-02
Abstract: 1. Amorphous torasemide modification characterized by the following data: DSC: exothermic maximum at a temperature of about 147 degree C (onset at about 144 degree C); X-ray powder pattern (2theta): no diffraction maxima due to the amorphous nature; IR characteristic absorption bands at 2900 to 3366 cm<-1> and at 1400 to 1703 cm<-1>. 2. Amorphous torasemide modification according to claim 1, characterized in that it is chemically pure. 3. Process for the preparation of the amorphous torasemide modification according to claim 1, characterized in that torasemide modifications are dissolved in water with or without the addition of a base at a temperature from 5 C to 100 degree C within 5 minutes to 24 hours and then the solutions are cooled to a temperature from-20 C to-70 degree C and water is removed. 4. Process for the preparation of the amorphous torasemide modification according to claim 3, characterized in that as the torasemide modifications crystal torasemide modifications I, II or III or an amorphous torasemide modification or any mixture of the crystal torasemide modifications I, II and II and of an amorphous torasemide modification are used. 5. Process for the preparation of the amorphous torasemide modification according to claim 3, characterized in that lyophilization is used as the method for the removal of the water and the base. 6. The amorphous torasemide modification according to claim 1, characterized in that it is used as a raw material for the preparation of pharmaceutically acceptable torasemide salts. 7. The amorphous torasemide modification according to claim 1, characterized in that, as a form of torasemide, it is used as a diuretic, as an agent for preventing heart or heart tissue damages caused by metabolic or ionicabnormalities associated with ischemia, in the treatment of thrombosis, angina pectoris, asthma, hypertension, nephroedema, pulmonary edema, primary and secondary aldosteronism, Bartter's syndrome, tumour, glaucoma, for decreasing intraocular pressure, acute or chronic bronchitis, in the treatment of cerebral edema caused by trauma, ischemia, concussion of the brain, metastases or epileptic attacks and in the treatment of nasal infections caused by allergens. 8. A pharmaceutical form, characterized in that, as the active ingredient, it contains an effective amount of the amorphous torasemide modification according to claim 1 without or, for that purpose, combined with one or more pharmaceutically acceptable additives such as sugar, starch, starch derivatives, cellulose, cellulose derivatives, mould release agents, and antiadhesive agents and possibly agents for flowability regulation. 9. A pharmaceutical form according to claim 8, characterized in that it is a tablet, a capsule or an injection.
Patent EA-004828-B1 (EA)
Title: Motor vehicle framework
Inventor: ANDRONOV YURY PAVLOVICH
IPC: B62D23/00
Filed: 2003-07-21
Abstract: 1. Motor vehicle framework having: - front, middle and rear parts formed by side members, cross members and verticals comprising a pair of pillars of the front part connected to each other with a cross member, a pair of pillar of the rear part connected to each other with a cross member, and two pairs of door pillars of the middle part spaced at the corresponding doorway width, the lower ends of front and rear pillars of each pair being connected to each other with a threshold-forming side member, while the lower ends of front pillars of diverse pairs and the lower ends of rear pillars of diverse pairs being connected to each other with a corresponding cross member, - side members, cross members and sloping member forming a framework of the roof and of the windscreen, side, vertical and sloping 'reinforcement members fixed at different levels of the front, middle and rear parts of the framework; - step-shaped reinforcement members fixed on different levels at the lower half of the rear part of the framework, of which alt members are connected to each other by means of welded joint; - upper ends of rear standing pillars of each pair of the middle part being additionally connected to each other with the first cross member of the roof framework, of which sloping members on one side are fixed on upper ends of front pillars of each pair of the middle part, while on the other side they are connected to each other with the second cross member of the roof framework, which is connected to the first cross member of the roof framework with its two side members; - all sloping reinforcement members of the framework being fixed between its side and vertical reinforcement members; - step-shaped reinforcement members of the tower half of the rear part of the framework being fixed between its cross members and side reinforcement members. 2. Motor vehicle framework according to Claim 1, characterized in that all members of the framework, except members forming the roof framework, constitute metal tubular elements of rectangular cross-section. 3. Motor vehicle framework according to Claim 1, characterized in that all members of the roof framework constitute metal tubular elements of circular cross-section. 4. Motor vehicle framework according to Claim 1, characterized in that cross members and side members, as well as reinforcement vertical, sloping and step-shaped members of the rear part of the framework form compartments for mounting a gas cylinder, a petrol tank and a spare wheel. 5. Motor vehicle framework according to Claim 1, characterized in that the front part of the framework comprises brackets for mounting headlamps.
Patent EA-010022-B1 (EA)
Title: Compounds having prolyl oligopeptidase inhibitory activity
Inventor: GYNTHER JUKKA
IPC: C07D295/185
Filed: 2004-01-02
Abstract: The invention provides a compound of formula (I),wherein in the formula X, R, Rand Rare as defined in the claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as a prolyl oligopeptidase inhibitor. The compounds of formula (I) can be used for the treatment of diseases or conditions where prolyl oligopeptidase inhibitors are indicated to be effective, for example for the treatment of neurodegenerative diseases, such as Alzheimer's disease and senile dementia.
Patent EA-012529-B1 (EA)
Title: Plasma reactor and process for producing lower-energy hydrogen species
Inventor: MILLS RANDELL L
IPC: C23C16/27
Filed: 2004-04-08
Abstract: A plasma reactor is provided to generate power and novel hydrogen species and compositions of matter comprising new forms of hydrogen via the catalysis of atomic hydrogen and to generate a plasma and a source of light such as high energy light, extreme ultraviolet light and ultraviolet light, via the catalysis of atomic hydrogen, the reactor comprising a plasma forming energy cell for the catalysis of atomic hydrogen to form novel hydrogen species and compositions of matter comprising new forms of hydrogen, a source of catalyst for catalyzing the reaction of atomic hydrogen to form lower-energy hydrogen and release energy, a source of atomic hydrogen, and a source of intermittent or pulsed power to at least partially maintain the plasma. The power balance is optimized by maximizing the output power from the hydrogen catalysis reaction while minimizing the input power by controlling the parameters of the input power to initiate or at least partially maintain the plasma such as the power density, pulse frequency, duty cycle, and peak and offset electric fields.
Patent EA-008336-B1 (EA)
Title: Power cycle with liquefied natural gas regasification
Inventor: MAK JOHN
IPC: F17C9/04
Filed: 2003-08-26
Abstract: Liquefied natural gas (LNG) or components thereof are used as working fluids in power generation cycles in a LNG regasification plant. Especially preferred plant configurations will be able to process LNG of different composition while generating on-spec pipeline gas, CNG, LNG vehicle fuel, and LPG.
Patent EA-013512-B1 (EA)
Title: Device for reading out exposed imaging plates
Inventor: THOMS MICHAEL
IPC: G01T1/29
Filed: 2006-08-23
Abstract: A combined device (10) for reading out and erasing imaging plates (30) comprises an eraser (14) disposed downstream of a readout unit (12) at a short distance thereof, said eraser being separated from the readout unit (12) by a light barrier (46).
Patent EA-017637-B1 (EA)
Title: Glazing
Inventor: REUTLER PASCAL
IPC: B32B17/06
Filed: 2007-03-06
Abstract: The invention relates to a substrate (10) provided with a stack of thin layers comprising alternating "n" functional layers (40, 80) with infrared reflectance and/or solar radiation reflectance properties, and "(n+1)" coatings (20, 60, 200) where n is a whole number ≥2, said coatings consisting of a plurality of dielectric layers (24, 26; 64, 66; 104) such that each functional layer (40) is arranged between the two coatings (20, 60, 100), at least two functional layers (40, 80) being respectively arranged on a wetting layer (30, 70) which is in turn respectively arranged directly on a subjacent coating (20, 60). The inventive substrate is characterised in that two subjacent coatings (20, 60) each comprise at least one dielectric layer (24, 64) and at least one non-crystallised smoothing layer (26) consisting of a material different from the material of the dielectric layer inside each coating, said smoothing layer (26) being in contact with the subjacent wetting layer (30).The invention is also characterised in that since the two subjacent coatings (20, 60) have different thicknesses, the thickness of the smoothing layer (26, 66) of the subjacent coating (20, 60) having a total thickness which is lower than that of the other subjacent coating is lower than or equal to the thickness of the smoothing layer (66, 26) of said other subjacent coating (60, 20).
Patent EA-014795-B1 (EA)
Title: System for attaching a hinge on an automobile door leaf
Inventor: BRIAULT MICHEL
IPC: E05D5/02
Filed: 2008-03-04
Abstract: According to the invention, the system for attaching a hinge on a door leaf of an automobile includes at least two riveted self-punched connections that clamp the hinge and the door leaf.
Patent EA-022021-B1 (EA)
Title: Vial adapter element
Inventor: SHEMESH ELI
IPC: A61J1/20
Filed: 2010-01-13
Abstract: A vial adapter element (10) for use in a drug mixing system including a body, a vial connection port (12) extending from the body (17), a hollow vial puncturing spike (14) that protrudes into the vial connection port and is in fluid communication with a syringe-adapter-element connection port that extends from the body, and a plurality of resilient tongues (20) spaced around an inner wall of the body, the tongues being located in gaps formed in the inner wall of the body, wherein said body comprises an outwardly extending continuous proximal rim extending from the connection port for connection with the vial.
Patent EA-018362-B1 (EA)
Title: Pyridazinone derivatives
Inventor: DORSCH DIETER
IPC: A61K31/501
Filed: 2009-03-24
Abstract: Compounds of the formula (I)where R, R, R, W and D are as indicated in claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be used for the treatment of tumors, among other things.
Patent EA-021824-B1 (EA)
Title: Electrical switch with pivoting switching member and improved supporting fulcrum and method for manufacturing said switch
Inventor: BERTAGNA FABIO
IPC: H01H1/22
Filed: 2009-06-26
Abstract: The invention relates to an electrical switch comprising at least two connection terminals (T1, T2), a fixed electrical contact (3) electrically connected to one (T2) of the two connection terminals (T1, T2), a pivoting and electrically conductive switching member (2), comprising at least one mobile electrical contact (4), suitable for oscillating between two preset positions, in one of which the mobile electrical contact (4) is in abutment against the fixed electrical contact (3), a supporting fulcrum (1) for the pivoting switching member (2), the supporting fulcrum (1) being electrically conductive and electrically connected to the other of the two connection terminals (T1). The supporting fulcrum (1) further includes mechanical coupling means (5) suitable for constraining the pivoting switching member (2) to the supporting fulcrum (1).
Patent EA-018770-B1 (EA)
Title: Device for manual dispensing carbonated and/or foamy beverages
Inventor: BUCHIK SERGEI ALEKSANDROVICH
IPC: B67C3/24
Filed: 2009-03-10
Abstract: The invention relates to food industry, particularly to shop equipment used for pouring beverages from a pressurised container into plastic bottles. A device has reliable performance and simple technical maintenance. The device has a body (1) inside of which there are supply canals (2 and 3) with elements (4 and 5) for connecting to the lines supplying gas and beverage respectively from a pressurised container and axisymmetrical cavity (6) having three tandem annular chambers (7, 8 and 9). The first (7) and the third (9) chambers have the gas and beverage supplying lines (2 and 3) connected. Downcomer (10) is secured vertically in the lower part of the body (1) and has an elastic sealing (11) on the source side of the open lower butt, the internal cavity (12) of which has a discharge channel (13) connected with the second annular chamber (8) of the axisymmetrical cavity (6) of the body (1). There is a three-way cock in the axisymmetrical cavity (6) of the body (1) that is made as a hollow valve (14) with radial through holes (15 and 16) with a possibility of longitudinal out-in traverse with the handle (17) and fixation in three positions. One of the supply canals in two of these positions is connected with the discharge channel (13) and in the third position it is connected with a possibility of disconnecting all the channels (2 and 3). There is a foam suppression assembly (12) in the downcomer cavity (10) that is made as a nozzle (18) with an axial through channel (19), a cylindrical part with a spiral escape channel (20) on the outside surface and a convergent shank end. There is a throttle valve (22) installed in the body (1) connected with the through axial channel (19) of the nozzle (18) by means of entrance channel (23) and the mechanism of clamping the plastic bottle mouth to the escape channel (20).
Patent EA-022084-B1 (EA)
Title: Spirooxetane derivatives of uracyl-containing nucleosides
Inventor: JONCKERS TIM HUGO MARIA
IPC: C07H19/10
Filed: 2010-05-11
Abstract: Compounds of the formula (I) are disclosedincluding any possible stereoisomers thereof, wherein Ris a monophosphate, diphosphate or triphosphate ester; or Ris a group of formulaRis optionally substituted phenyl or naphthyl; Ris hydrogen or C-Calkyl; Ris hydrogen or C-Calkyl; or one of Rand Ralso forms phenyl; Ris C-Calkyl or benzyl; or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical formulation based thereon and the use of compounds I as HCV inhibitors.
Patent EA-022163-B1 (EA)
Title: PI3 KINASE/mTOR DUAL INHIBITORS
Inventor: BARDA DAVID ANTHONY
IPC: C07D471/04
Filed: 2012-01-11
Abstract: The present invention provides an imidazo[4,5-c]quinolin-2-one compound, or a pharmaceutically acceptable salt thereof, that inhibits both PI3K and mTOR and, therefore, is useful in the treatment of cancer.
Patent EA-024509-B1 (EA)
Title: Dosage form, process for preparing same amd method of treating
Inventor: MOHAMMAD HASSAN
IPC: A61P25/04
Filed: 2011-12-09
Abstract: The present invention provides a dosage form, a process for preparing the same and a method of treating, and the dosage form comprises non-stretched melt extruded particulates comprising a drug which is an opioid agonist and a matrix; wherein the melt extruded particulates are present as a discontinuous phase in the matrix; wherein the matrix comprises a continuous phase comprising a gel-forming agent and wherein the particulates comprise acrylic acid alkyl ester and methacrylic acid alkyl ester copolymer.
Patent EA-025833-B1 (EA)
Title: Method of determining viability of new-born animals
Inventor: DMITRIEV ANATOLY FEDOROVICH
IPC: A61B5/01
Filed: 2014-11-25
Abstract: The invention relates to veterinary medicine and is provided for determining viability of new-born animals, in particular, piglets, in an early neonatal period. The technical result of the new-born animals viability determining method is time and cost saving. The method comprises determination of temperature and body weight parameters within the first 24 hours of life. The animal body temperature is measured immediately after birth (T a.b) and after 1, 2, 4, 6, 12, 24 hours (T a.), and the body weight is measured after birth (W a.b) and after 24 hours (W a.). Then the average value of body temperature of each animal in the time aspect, in 1-24 h after birthaverage value of body temperature for a group of animals immediately after birthand in 1, 2, 4, 6, 12, 24 h after birthare calculated. In a similar way, average values of body weight for the group of animals immediately after birthand in 24 h after birthare calculated. On the basis of average temperature and body weight values, the viability index is calculated.
Patent EA-030749-B1 (EA)
Title: Acellular pertussis vaccine
Inventor: POOLMAN JAN THEUNIS
IPC: A61K39/02
Filed: 2014-03-06
Abstract: The present invention relates to an acellular pertussis (aP) vaccine composition comprising Bordetella pertussis antigens pertussis toxoid (PT), filamentous hemagglutinin (FHA), and fimbriae types 2 and 3 (FIM), and optionally pertactin (PRN), wherein FIM is present in an amount of 12-100 μg per human dose.
Patent EA-028388-B1 (EA)
Title: Polymer-rubber composition and method of production thereof
Inventor: RIZAEV ELDAR GUSEJNOVICH
IPC: C08L67/02
Filed: 2016-03-25
Abstract: The invention relates to the rubber industry and the construction industry, in particular to compositions of high molecular compounds and methods for their production from worn tires recycled into rubber chips and recycled to chips waste packaging from polyethylene terephthalate (PET) with obtaining, by way of copolymerization from a mixture of these components at a given temperature, the polymer-rubber composition "DANPOL" of the general formulaThe method for production of the "DANPOL" composition includes a process of copolymerization of vulcanized rubber crumb with PET-chopped grain in a ratio of 60-90% by weight of rubber crumb to 10-40% by weight of PET-chopped grain by gradually increasing the temperature of the mixture of these components, depending on the conditions of the copolymerization process, the temperature of the mixture is brought to 140-160°C within about 7 to 30 minutes, then at the second stage the temperature of the mixture is increased to 220-240°C within about 15 to 60 minutes, then at the third stage the temperature of the mixture is gradually reduced to 180-200°C within about 7 to 20 minutes, with carrying out copolymerization of the components of the reaction mixture at this temperature. The "DANPOL" composition can be used for production of various building materials: paving slabs, facade tiles, laminate boards, roofing tiles, building blocks, etc.
Patent EA-036561-B1 (EA)
Title: Glazing comprising a closed insert seal portion and method of manufacturing said glazing
Inventor: BLANC OLIVIER
IPC: B60J1/02
Filed: 2014-09-26
Abstract: An object of the invention is glazing (1) comprising a glazed element (2), at least one profiled seal portion (3) and at least one insert (4) situated at least partially inside said profiled seal portion (3), said insert (4) having, along a main part (P) which is in said profiled seal portion (3), in cross section, a section closed up on itself in the form of a loop to form a hollow (40), characterized in that said main part (P) at one end (44, 45) and preferably at two opposite ends (44, 45) comprises a plug (5) which closes said end and preferably said ends.
Patent EA-033015-B1 (EA)
Title: Threaded joint for steel pipes
Inventor: OKU Yousuke
IPC: F16L15/04
Filed: 2015-06-19
Abstract: A threaded joint is constructed of a pin (10) and a box (20). The pin (10) includes, in order from a tubular body having the pin (10) toward the free end thereof, a male threaded portion (11) and a lip portion (12) including a sealing surface (13). The box (20) includes a female threaded portion (21) corresponding to the male threaded portion (11) of the pin (10) and a recessed portion (22) corresponding to the lip portion (12), the recessed portion (22) including a sealing surface (23). The lip portion (12) includes, in order from a male threaded portion (11) toward the free end of the pin (10), a neck portion (14) and a sealing head portion (15) including the sealing surface (13). The maximum outside diameter (D) of the region of the sealing surface (13) in the sealing head portion (15) is larger than an outside diameter (D) of the neck portion (14) at a boundary between the neck portion (14) and the male threaded portion (11). This threaded joint is capable of reliably providing high sealing performance while maintaining high torque resistance performance of dovetail-shaped tapered threads.
Patent EA-035883-B1 (EA)
Title: Production of tert-butyl esters of ethylenically unsaturated carboxylic acids
Inventor: HORSTMANN CATHARINA
IPC: C07C67/54
Filed: 2016-11-28
Abstract: A process for continuously producing the tert-butyl ester of an ethylenically unsaturated carboxylic acid comprising the following steps: a) an ethylenically unsaturated carboxylic acid is reacted with isobutene in the presence of an acidic catalyst to give an esterification mixture; b) the acidic catalyst is removed; c) low-boiling-point constituents are removed; and d) a liquid containing tert-butyl ester is introduced into a distillation device and the product is purified by distillation in the distillation device, where d1) the liquid containing tert-butyl ester is separated in the distillation device to give a gaseous overhead product containing tert-butyl ester and a liquid bottom product containing carboxylic acid; d2) the gaseous overhead product containing tert-butyl ester is at least to some extent condensed and some of the condensate is returned to the distillation device; d3) the liquid bottom product containing carboxylic acid is at least to some extent returned to step a); d4) liquid bottom product containing carboxylic acid is drawn off and conducted to a heater, a superheated liquid return stream is taken from the heater and the superheated return stream is depressurized into the distillation device; and d5) at least in the overhead region of the distillation device those walls of the distillation device that are in contact with the vapours are thermally insulated and/or heated at least in some regions. The separation of the tert-butyl ester from unreacted carboxylic acid in the process proceeds with a particularly small extent of polymerization both of the tert-butyl ester and of the carboxylic acid.
Patent ES-2167264-B1 (ES)
Title: Sistema para control de presencia.
Inventor: USON SOBREVIELA FRANCISCO J
IPC: G08B13/18
Filed: 2000-08-28
Granted: 2003-10-16
Abstract: Sistema para control de presencia, de utilidad preferente para el control de zonas (1) alejadas de núcleos urbanos, haya o no suministro de energía eléctrica, comprendiendo un equipo de detección y comunicación de paso dotado de los unos medios (2) de alimentación energética y comunicado con un receptor telefónico (8), constituyéndose dicho equipo de detección por una batería (3) alimentada por los medios (2) de alimentación energética, a través de un regulador de carga (4), estando comunicada la batería (3) a unos medios (5) de detección de paso y a una placa electrónica (6) de control que gestiona todo el sistema, estando comunicada dicha placa electrónica (6) de control con los medios (5) detectores de paso, y controlando, igualmente, un transmisor telefónico (7) de voz-datos que envía la señal generada, al detectar el paso por el respectivo acceso A-F, a un receptor telefónico (8).