baber/WOPTO huggingface dataset:
Patent DE-69714590-D1 (DE)
Inventor: BRETTING AAGE
IPC: A61P19/10
Filed: 1997-05-15
Granted: 2002-09-12
Abstract: The present invention relates to compounds of formula (I), in which formula X is hydrogen or hydroxy; R1 and R2, which may be the same or different, stand for hydrogen or a C1-C3 alkyl radical; or R1 and R2, taken together with the carbon atom bearing the group X, can form a C3-C6 carbocyclic ring, R3 stands for a C1-C3 alkyl radical, an aryl or an aralkyl radical, or for YR4, in which Y stands for the radicals -CO-S-, -CS-O- or -CS-S-, and R4 stands for a C1-C3 alkyl radical or an aryl or an aralkyl radical; Q is (CH2)n, n being 1-4. R1, R2 and Q independently may optionally be substituted with one or more fluorine atoms. The compounds show strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells as well as immunomodulating and antiinflammatory effects.
Patent DE-69719756-D1 (DE)
Inventor: HUOVILA JYRKI
IPC: D21F1/02
Filed: 1997-06-18
Granted: 2003-04-17
Abstract: A method and apparatus for combining a dilution flow with a stock flow passed out of an inlet header in a paper/board machine including dilution flow ducts through which the dilution flow is passed to selected locations across the width of the headbox of the paper/board machine in order to regulate the basis weight of the paper/board web. The dilution flow ducts are constructed so that they becomes narrower toward a final, downstream end. Branch ducts are placed in the area of the narrowing portion of each flow duct, and the dilution flow is passed out of the branch ducts into the system of pipes wherein the dilution flow is combined with the stock flow passed out of the inlet header.
Patent DE-69726163-D1 (DE)
Inventor: RAADSEN JAN
IPC: G07F7/02
Filed: 1997-08-15
Granted: 2003-12-18
Abstract: A gift token has a card-like handy body member with an appropriate imprint and representing a certain exchange-value which is exchangeable for a chosen good. The body member includes an integrated circuit with an electronically readable and programmable memory, intended for the storage (at least temporarily) of the above-mentioned exchange value, in a way which is compatible with an existing electronic payment system.
Patent DE-69728464-D1 (DE)
Inventor: SUZUKI TAKAO
IPC: G01N21/21
Filed: 1997-04-17
Granted: 2004-05-13
Abstract: An apparatus for measuring magneto-optical effect includes a light source 102, a spectroscope 120, a first polarizer 150 to polarize the light with a required wavelength taken out by the spectroscope 120, means 172 for applying magnetic field on a sample 176, a second polarizer 156 to admit the light transmitted or reflected by a sample 176 to pass, a photo-detector 162 for detecting intensity of light that has passed the second polarizer 156. The light source 102 includes a heavy hydrogen lamp and the spectroscope does not contain a lens and/or prism. A light path from the light source to the photo-detector is housed in a container, and the container is filled with a gas containing no oxygen. <IMAGE>
Patent DE-69733343-D1 (DE)
Inventor: KAY BARRINGTON
IPC: G01N33/68
Filed: 1997-03-20
Granted: 2005-06-30
Abstract: A peptide as described in any one of Sequence I.D. Nos 1 to 56 herein.
Patent DE-69736704-D1 (DE)
Inventor: FEENSTRA WILLEM
IPC: C07D413/12
Filed: 1997-03-20
Granted: 2006-11-02
Abstract: The invention relates to a group of new piperazine and piperidine compounds having interesting pharmacological properties. It has been found that compounds of formula (a) wherein A represents a heterocyclic group of 5-7 ring atoms wherein 1-3 heteroatoms from the group O, N and S are present; R1 is hydrogen or fluoro; R2 is C1-4-alkyl, C1-4-alkoxy or an oxo group, and p is 0, 1 or 2; Z represents carbon or nitrogen, and the dotted line is a single bond when Z is nitrogen, and a single or double bond when Z is carbon; R3 and R4 independently are hydrogen or C1-4-alkyl; n has the value 1 or 2; R5 is halogen, hydroxy, C1-4-alkoxy or C1-4-alkyl, and q is 0, 1, 2 or 3; Y is phenyl, furanyl or thienyl, which groups may be substituted with 1-3 substituents of the group hydroxy, halogen, C1-4-alkoxy, C1-4-alkyl, cyano, aminocarbonyl, mono- or di-C1-4-alkylaminocarbonyl; and salts thereof show high affinity for both the dopamine D2 and serotonin 5-HT1A receptors.
Patent DE-69814126-D1 (DE)
Inventor: BOUIX F
IPC: A45D40/18
Filed: 1998-10-20
Granted: 2003-06-05
Abstract: The present invention is an airtight case comprising a base for receiving a stick-type product, a hollow cap, and a hollow plug sleeve inserted within the cap. The plug sleeve has an open end and a closed end, the closed end being a flexible bellows. This case is useful in reducing the adverse effects caused by the pressure build-up associated with sealing or airtight cases. When the cap of the present invention is placed on the base of the case the bellows expands in response to the compressing of the air located within the inner chamber of the case, thus preventing the cap from being pulled away from the base. Also, when the cap is removed, the bellows contracts and prevents the product from being pulled out of the base.
Patent DE-69816127-D1 (DE)
Inventor: CAVALLA DAVID
IPC: A61P25/28
Filed: 1998-12-11
Granted: 2003-08-07
Abstract: The present invention comprises a method of synthesizing compounds of formula (I): wherein Z, R1, R2, R3, R4 and R8 are as described herein; comprising the steps of. (a) reacting a compound of the formula (II) with an effective amount of ethyl cyanoacetate to form a compound of the formula (III) (b) subjecting said compound (III) to successive steps of nitrosating with a nitrosating agent to form a nitro group [amination], reduction of the nitro group to an amine group with a reducing agent, and [amidation] acylation of the amine group to an amide group with an acylating agent, to form compound (IV) (c) reacting said compound (IV) with an effective amount of a base to form compound (V) (d) reacting said compound (V) with an effective amount of a desulfurization compound to form compound (VI)  and (e) subjecting said oxo group of compound (VI) to the successive steps of halogenation with a halogenating agent and displacement with an amine of the formula NR1R2, wherein R1 and R2 are as defined above, to form said compound of formula 1.
Patent DE-69817894-D1 (DE)
Inventor: CRISP RONALD ANTHONY
IPC: C09D9/00
Filed: 1998-02-18
Granted: 2003-10-16
Abstract: The present invention relates to a stripping composition for removing coatings, in particular organic coatings, from metal substrates particularly those which are easily corroded or damaged. More particularly the invention is directed to a method of removing an organic coating, in particular paint, from a substrate comprising a soft metal eg aluminium, magnesium or zinc, which substrate can be easily damaged or etched by the effect of water and a strong alkali. The composition comprises a component which penetrates the coating and swells or solubilizes it; a strong alkali accelerator which breaks down the coating enabling it to be removed and a coupling agent characterised in that the component which penetrates the coating and swells or solubilizes it comprises benzyl alcohol and the coupling agent comprises a glycol, a glycol ether or mixtures thereof. The method comprises stripping a coating from a metal substrate in a stripping bath containing water and a stripping composition of the invention wherein a silicic is introduced into the stripping bath:     as part of the stripping composition;   as part of a replenishing composition;   by addition together with or separately from a strong alkali accelerator using a dis-solution chamber through which the stripping composition is pumped or by dissolving it into rinse water so that water which is carried back into the bath carries the silicic with it.
Patent DE-69828902-D1 (DE)
Inventor: GAMBETTA A
IPC: C12P13/00
Filed: 1998-11-16
Granted: 2005-03-10
Abstract: The present invention relates to isolated polypeptides having 5-aminolevulinic acid synthase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
Patent DE-69833433-D1 (DE)
Inventor: AGRE H
IPC: H04W4/02
Filed: 1998-04-07
Granted: 2006-04-20
Abstract: A mobile telephone system employs a fleet of satellites (14) and a set of gateway ground stations (10) arranged around the globe for handling communications to and from mobile communication subscriber units (12) such as mobile telephones. Signals are transmitted between a subscriber unit (10) and the nearest gateway (10) via one or more of the satellites. The gateway system is configured to process telephone call connection requests from a mobile subscriber unit (12) based upon the location of the subscriber unit. The location of the subscriber unit is employed, for example, to determine how telephone numbers are to be parsed and how to properly route emergency telephone calls to the nearest appropriate emergency service centers. Multiple location mapping schemes are employed to facilitate a determination of the location of a subscriber unit and to assist in routing emergency calls. In one implementation, each location with the service area of the system is mapped into a set of uniformly sized and shaped information cells (802). Each information cell includes pointers to data structures (806, 808) defining, among other things, the service providers that are permitted to process calls to or from that location and the nearest emergency services center. Each location is also mapped into at least one virtual service provider cell (812, 814, 816, 818, 820) which includes service provider preferences and requirements for handling a call to from that location and including a unique location identifier. A specific implementation for use with the Global System for Mobile Communication (GSM) is described.
Patent DE-69839376-D1 (DE)
Inventor: POLSTER LOUIS S
IPC: A23L15/00
Filed: 1998-12-23
Granted: 2008-05-29
Abstract: An apparatus, a method and a flat for pasteurizing a plurality of layers of in-shell eggs without substantially impairing the functionality of the in-shell eggs. The apparatus includes a fluid bath, heat exchangers, a means for vertically perturbating the entire surface of in-shell eggs loosely held in a plurality of flats forming at least one stack thereof.
Patent DE-69839919-D1 (DE)
Inventor: HOW DANA
IPC: G01R31/3185
Filed: 1998-11-23
Granted: 2008-10-02
Abstract: A system for testing an integrated circuit, and particularly a gate array, is disclosed which includes, prior to coupling the array to form a user-designed circuit, predesigned logic that enables testing of the user-designed circuit. The predesigned logic allows logic blocks in the array to operate in "freeze" mode or to operate in normal mode, where normal mode is defined by the user-designed circuit. Much of the same circuitry in the logic blocks is, in fact, used in both modes of operation, thus minimizing circuitry added due to test. When the logic blocks are selected to be frozen, the logic blocks behave as a series of daisy-chained master-slave flip-flops. Stimulus data is shifted into the array and captured data is shifted out of the array through the daisy-chained flip-flops. Nonetheless, when data is shifted into and out of the daisy-chained flip-flops, the master latch and the slave latch of each flip-flop can be set to receive independent values and the data captured by each of the master and slave latches can be independently shifted out and analyzed. Although when frozen, the logic blocks behave as daisy-chained flip-flops, use of the logic blocks for testing purposes does not depend upon placement of sequential elements in the user-designed circuit in the logic blocks. In other words, in normal mode, a logic block can implement combinational, sequential, or other functions and still later be used to drive out stimulus values or capture results. Moreover, each logic block is further equipped for addressable mode control, allowing selected logic blocks to be exercised in isolation once stimulus data is shifted in, simplifying test generation and improving fault coverage. Using a logic block in accordance with the invention results in a high level of fault coverage, while placing few limitations on the user's circuit design.
Patent DE-69839939-D1 (DE)
Inventor: WEISS ANTHONY STEVEN
IPC: A61K31/7088
Filed: 1998-07-17
Granted: 2008-10-09
Abstract: The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.
Patent DE-69902274-D1 (DE)
Inventor: ALVAREZ BERENGUER ANTONIO
IPC: C04B28/02
Filed: 1999-05-12
Granted: 2002-08-29
Abstract: A new additive for projectable conglomerate building materials that comprises at least a rheological grade clay, preferably sepiolite, a water reducing agent/flux and an aerating agent, as well as the use of this additive as a component of projectable conglomerate building materials, such as mortar and concrete, is described.
Patent DE-69903055-D1 (DE)
Inventor: BOURDAT MICHEL
IPC: B08B3/10
Filed: 1999-11-04
Granted: 2002-10-24
Abstract: The invention concerns a method and a machine for cleaning objects in plate form such as screen printing stencils. The method consists in: immersing an object (2) to be cleaned in a cleansing composition bath consisting of an azeotropic liquid solution having a density not less than the density of residues of average density likely to soil the object (2), and adapted to loosen the residues from the object (2) without solubilising them. The object (2) is placed in a vessel with vertical walls at a distance less than 10 cm from the vertical faces of the object (2). The treating vessel (1) spills over into an overflow vessel (8). The cleansing composition is continuously removed from both vessels (1, 8), filtered and re-introduced in the treating vessel (1) top part.
Patent DE-69909993-D1 (DE)
Inventor: CHARMES MICHEL
IPC: B29K105/00
Filed: 1999-04-16
Granted: 2003-09-04
Abstract: A process for reconstituting or reconstructing a composite object having a defect which affects at least its surface includes: (a) placing at least one added piece or material, the shape and dimensions of which are matched to those of the defect, in or on the defect, the piece or material including mechanically strong, continuous or staple fibers; (b) placing a polymer material in or on the defect to obtain a plastic matrix in which the fibers are distributed; (c) placing a gas-drain for draining the gases given off by the plastic matrix and a cover for extracting the gases, in succession and one on top of the other, on the added piece, which together with the rest of the object form an enclosure which is sealed with respect to the external atmosphere and circumscribes the defect and the added piece; and (d) while evacuating the sealed enclosure, heating the added piece using a radiant source, the emission from which includes infrared radiation, and placing the source with respect to the defect so as to irradiate the cover for extracting the gases given off by the plastic matrix. Wherein, the composite object including a cellular layer, a first resin is deposited at the bottom of the defect, a cellular replacement part is then inserted, a second resin is deposited on the exposed part of the cellular part together with at least one piece of a fabric of the continuous or staple fibers, and at least one operation consisting of (c) and (d) is carried out, such that the radiant source has an effect beyond the cellular layer.
Patent DE-69913509-D1 (DE)
Inventor: SOUTHERN EDWIN MELLOR
IPC: C12Q1/6872
Filed: 1999-05-17
Granted: 2004-01-22
Abstract: A method of making a set of labelled compounds by the use of a preferably particulate support, comprises dividing the support into lots, performing a different chemical reaction on each lot of the support, e.g. to couple a chemical moiety to that lot of the support, tagging a fraction of each lot of the support with a different label, and combining the said lots of the support. The steps are repeated several times, preferably to build up oligomer molecules carrying labels which identify the nature and position of a monomer unit of the oligomer, and which are releasable from the support. Preferred labels, which are releasable from the compounds by cleavage to provide charged groups for analysis by mass spectrometry, are groups of the trityl (trimethylphenyl) family. Also claimed are libraries of these labels and their use in assays and nucleic acid analysis methods. <IMAGE>
Patent DE-69914940-D1 (DE)
Inventor: BLOCH JEAN-FRANCOIS
IPC: C12Q1/6816
Filed: 1999-12-08
Granted: 2004-03-25
Abstract: Method for detecting a known function from nucleic acids (NA) in a sample comprises: (1) preparing, from NA, sequences (NA1) comprising the gene(s) (I), encoding proteins (II) corresponding to the function, plus control elements required for their transcription and translation; (2) in vitro transcription and translation of NA1; and  (3) detection and/or measurement of the function of (II) produced.  Independent claims are also included for the following:  (1) kits for performing this method; and  (2) support, comprising a series of sites for performing the new method, in which each site allows detection and/or measurement of a different function.
Patent DE-69915290-D1 (DE)
Inventor: RUIJTEN MARIE
IPC: A61K36/00
Filed: 1999-06-18
Granted: 2004-04-08
Abstract: A compound is extracted from vegetable material, wherein the vegetable material is reduced and treated with a solvent. According to the invention, the vegetable material is frozen using a liquid nitrogen and in frozen condition reduced in size. According to two important embodiments, the vegetable material comes from the ginkgo tree, in particular fresh leaves, and water is used as a solvent. The invention also relates to a pharmaceutical preparation and a cosmetic preparation comprising as active component a compound obtained by the method according to the invention.
Patent DE-69915425-D1 (DE)
Inventor: ROESLER RICHARD R
IPC: C08G18/78
Filed: 1999-10-01
Granted: 2004-04-15
Abstract: The present invention relates to moisture-curable compounds which     a) have an isocyanate group content (calculated as NCO, MW 42) of 0.2 to 30% by weight and an alkoxysilane group content (calculated as Si, MW 28) of 0.2 to 4.5% by weight,   b) optionally contain repeating ethylene oxide units and c) have an equivalent ratio of isocyanate groups to alkoxy groups, which are bound to Si, of 1.0:0.05 to 1.0:1.4, wherein the preceding percentages are based on the weight of the moisture-curable compounds and wherein the alkoxysilane groups are incorporated as the reaction products of polyisocyanates with amino compounds corresponding to formula I <CHEM>   The present invention also relates to coating, adhesive or sealing compositions containing these moisture-curable compounds as the binder.
Patent DE-69918235-D1 (DE)
Inventor: CURRIE JOHN
IPC: C08G77/08
Filed: 1999-08-25
Granted: 2004-07-29
Abstract: A process for producing a silicone polymer having a volatile material content of less than 1% by weight, preferably less than 0.1% by weight, comprises the sequential steps of (i) producing an unstripped silicone polymer by polymerisation of a linear silanol group containing siloxane by condensation polymerisation, or of a cyclosiloxane by ring-opening polymerisation, or of a mixture of said linear and cyclosiloxanes, with a phosphazene base in the presence of water and the presence or absence of a filler, (ii) neutralising the catalyst, and (iii) stripping the unstripped silicone polymer, preferably at temperatures of 200 DEG C and above.
Patent DE-69919305-D1 (DE)
Inventor: DUNAND MICHEL ANDRE
IPC: H01B7/00
Filed: 1999-12-02
Granted: 2004-09-16
Abstract: The connecting cable (10) holds a bundle of wires (16) and has a sleeve (18) defining an internal passage in the cable to allow insertion of supplementary wires at a later time. The initial bundle of wires (16) lies outside this internal sleeve.
Patent DE-69921686-D1 (DE)
Inventor: ABERG PER
IPC: B23K9/12
Filed: 1999-11-19
Granted: 2004-12-09
Abstract: The invention relates to a method for preventing the welding electrode sticking in the contact nozzle and a welding power source of the inverter type for MIG/MAG with these characteristics. A short fading of the current takes place before the welding current is switched off.
Patent DE-69923338-D1 (DE)
Inventor: FURMAN A
IPC: A61K31/662
Filed: 1999-11-02
Granted: 2005-02-24
Abstract: The present invention is directed to a method for treating hepatitis B virus infection in humans comprising administering a synergistically effective amount of agents having known anti-hepatitis B virus activity in combination or alternation. Specifically, the invention is directed to a method for treating hepatitis B virus infection comprising administering FTC in combination or alternation with penciclovir, famciclovir or Bis-POM-PMEA. Additionally, the invention is directed to a method for treating hepatitis B virus infection comprising administering L-FMAU in combination or alternation with DAPD, penciclovir or Bis-POM-PMEA. The invention is further directed to a method for treating hepatitis B virus infection comprising administering DAPD in combination or alternation with Bis-POM-PMEA.
Patent DE-69923779-D1 (DE)
Inventor: JONES LYNN
IPC: G01R31/36
Filed: 1999-09-29
Granted: 2005-03-24
Abstract: A method of testing applicable to the routine testing of batteries for automotive vehicles and like batteries is described. The method comprises: providing a battery to be tested; providing a test electrical load for connection to the battery; providing a control circuit to connect the load to the battery for an interval of less than one second; and providing analysis means to analyze the battery's reaction to said load. The invention is characterized by causing the load to cause the battery to deliver a macro-current which is comparable to currents arising in use of the battery; causing said control circuit to connect the load to the battery for a transient time interval lying in the range of up to 100 milliseconds; and providing the control circuit as part of handset apparatus adapted to be operated and connected to the battery in the manner of a testing handset, and the transient macro-current generating an amount of heat in relation to the handset which can be accommodated by apparatus of the handset kind.
Patent DE-69928697-D1 (DE)
Inventor: TECLE HAILE
IPC: A61K45/00
Filed: 1999-12-21
Granted: 2006-01-05
Abstract: Sulfohydroxamic acid diarylamines and derivatives thereof; compositions made from them; and methods of using them.
Patent DE-69933569-D1 (DE)
Inventor: DEBOER M
IPC: B65B1/04
Filed: 1999-07-26
Granted: 2006-11-23
Abstract: A probe and nozzle assembly for reducing the pressure at which a needleless injector must deliver medicament for proper delivery are disclosed. In one embodiment of the probe, the probe is retractably located within an injector nozzle assembly. Upon activation of the energy source a portion of the probe extends past the nozzle assembly to deliver the medicament through a discharge channel. After activation the probe retracts back into the nozzle assembly. In another embodiment, the probe is fixed to the end of the nozzle assembly. In both embodiments the ratio of discharge channel length to diameter is greater than 6/1.