baber/WOPTO huggingface dataset:
Patent NZ-228915-A (NZ)
Title: Nitromethylsulphonyl- substituted heterocyclic compounds, medicaments, and intermediates
Inventor: BROWN STEVEN PAUL
IPC: A61K31/343
Filed: 1989-04-27
Abstract: The invention concerns novel heterocyclic nitromethane derivatives of the formula 1 as defined hereinafter (and their non-toxic salts) wherein the heterocyclic moiety Q may bear a wide variety of optional substituents, together with pharmaceutical compositions containing them. The nitromethane derivatives are inhibitors of the enzyme aldose reductase and are of value in the treatment of certain complications of diabetes and galactosemia. The invention further concerns novel processes for the manufacture and use of said inhibitors.
Patent NZ-229681-A (NZ)
Title: Coating composition comprising an acrylate polymer containing at least two anhydride groups, a polyclycidyl compound, and a self-stabilised dispersed glycidyl acrylate-containing polymer
Inventor: BARSOTTI ROBERT J
IPC: C09D201/06
Filed: 1989-06-23
Abstract: A coating composition useful for a finish for automobiles and trucks in which the film forming binder contains reactive binder components of about   (a) 25-94% by weight, based on the weight of the binder, of an acrylic polymer having at least two reactive anhydride groups composed of polymerized monomers of an ethylenically unsaturated anhydride and polymerized monomers from the group consisting of alkyl methacrylate, alkyl acrylate and any mixtures thereof, wherein the alkyl groups have 1-8 carbon atoms and the polymer has a weight average molecular weight of about 2,000-50,000; (b) 5-50% by weight, based on the weight of the binder, of a glycidyl component having at least two reactive glycidyl groups; (c) 1-40% by weight, based on the weight of the binder, of a self-stabilized dispersed resin; and the composition contains about 0.1-5% by weight; based on the weight of the binder, of a catalyst.
Patent NZ-231145-A (NZ)
Title: Methyl alpha-acrylate derivatives substituted by a 5-membered heterocyclic ring, and compositions thereof
Inventor: SCHUETZ FRANZ
IPC: C07D333/18
Filed: 1989-10-25
Abstract: Heterocyclically substituted methyl  alpha -arylacrylates of the general formula <IMAGE>  in which R represents alkyl, alkenyl, haloalkyl, cycloalkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl, halogen or aryl, where the aromatic ring is optionally substituted, Het represents a radical optionally substituted five-membered heterocyclyl having 1 to 3 hetero atoms,  A represents ethenylene, ethylene, methyleneoxy or methylenethio, and fungicides and pesticides containing these compounds.
Patent NZ-240781-A (NZ)
Title: Bis pilocarpine ester derivatives and medicaments for glaucoma treatment.
Inventor: JARVINEN TOMI
IPC: C07D405/14
Filed: 1991-11-28
Abstract: The object of the invention are novel bispilocarpates useful in the treatment of glaucoma and having general formula (I), wherein A) Y is hydrogen or the acyl group (II), and W is the group -O-A-O-Z-Y', wherein Y' is hydrogen or the acyl group (III), the groups R and R' having different meanings and may be the same or different and A is an aliphatic or aromatic bridging group, and -Z-Y' is (IV), or B) W is OR, wherein R has the same meaning as above, Y is (V), where R' has the same meaning as above, B means the same as A and Z'-OR' is (VI) or C) W and Y together mean -A-O-Z-C-B-C-, where the symbols have the same meanings as above.
Patent NZ-241645-A (NZ)
Title: Process for the production of 1h-imidazo[4,5-c]quinolin-4-amines
Inventor: GERSTER JOHN FRANKLIN
IPC: C07D471/04
Filed: 1992-02-18
Abstract: A process and intermediates for preparing 1-substituted-1H-imidazo[4,5-c]quinolin-4-amines. The process involves reacting a 1-substituted-1H-imidazo[4,5-c]quinoline-5N-oxide with an isocyanate and hydrolysing the product thereof. Also, a process for preparing the intermediates is disclosed.
Patent NZ-242850-A (NZ)
Title: 17-carbamoyl androstane derivatives; medicaments, use, and methods of
Inventor: PANZERI ACHILLE
IPC: A61P5/24
Filed: 1992-05-21
Abstract: The present invention concerns steroidic 5 alpha -reductase inhibitors having the following formula (I) <CHEM>  wherein Y is oxygen or sulphur;  R is a group:     a) -OR4, wherein R4 is hydrogen or a C1-C6 alkyl group;   b) <CHEM> wherein each of R5 and R6, independently, is hydrogen or a C1-C6 alkyl group;   c) <CHEM>  wherein R7 is hydrogen or a C1-C6 alkyl group and W is a group:     (i) <CHEM> wherein R8 is a C1-C6 alkyl group, a C5-C6 cycloalkyl group, a C6-C9 cycloalkylalkyl group, a phenyl group or a benzyl group; or   (ii) <CHEM>  wherein R9 is a C1-C6 alkyl group or a C5-C6 cycloalkyl group; or   (iii) <CHEM>  wherein R5 and R6 are as defined above;     d) <CHEM> wherein each of R10 and R11 is, independently, hydrogen or a C1-C6 alkyl group or taken together with the nitrogen atom to which they are linked form a pentatomic or hexatomic saturated heteromonocyclic ring, optionally containing at least one additional heteroatom selected from oxygen and nitrogen, and n is an integer of 2 to 4; R1 is hydrogen, a C1-C6 alkyl group, a C5-C6 cycloalkyl group, a C6-C9 cycloalkyalkyl group or an aryl group; each of R2 and R3 is, independently, selected from the group consisting of hydrogen, C1-C6 alkyl, C5-C6 cycloalkyl, C6-C9 cycloalkylalkyl and aryl or R2 and R3, taken together with the nitrogen atom to which they are linked, form a pentatomic or hexatomic saturated heteromonocyclic ring, optionally containing at least one additional heteroatom selected from oxygen and nitrogen; and the symbol (----) represents a single or a double bond provided that when it is a double bond the hydrogen in the 5 alpha  position doesn't exist and the pharmaceutically acceptable salts thereof.   In view of their 5- alpha  reductase inhibiting activity the compounds of the invention can be useful for the treatment of androgen dependent conditions.
Patent NZ-261464-A (NZ)
Title: Concentrate-diluent proportioning dispenser with interchangeable proportioner
Inventor: SPRIGGS JOHN R
IPC: B08B5/02
Filed: 1994-01-06
Abstract: A system for diluting and dispensing concentrated liquid products is disclosed. The system includes a dispensing device (10, 150) containing a removable proportioning means such as an aspirator assembly (40, 154). A concentrate pickup tube (114) attaches to the dispensing device and is in fluid communication with the aspirator assembly. The dispensing device can utilize a rigid outlet tube (20, 159) which is removably attached to nozzle tip (18, 158) for dispensing to large containers. Also disclosed is a method for diluting and dispensing chemical solutions using the dispensing device of the invention.
Patent NZ-264745-A (NZ)
Title: Use of various 4-(fluorobenzoylamino) -chroman and -pyridopyran derivatives in the manufacture of medicaments
Inventor: EVANS JOHN MORRIS
IPC: C07D215/42
Filed: 1992-06-11
Abstract: Compounds of formula (I) or pharmaceutically acceptable salts thereof: <CHEM>  wherein: Y is C-R1 where R1 is methyl; R2 is hydrogen; R3 and R4 are each methyl; R5 is hydroxy; R6, R8 and R9 are each hydrogen; R7 is 4-fluorophenyl; the R8-N-CO-R7 group being trans to the R5 group; and X is oxygen are useful in the treatment and/or prophylaxis of anxiety and/or mania, and/or depression and/or the effects associated wit withdrawal from substances of above, and/or disorders treatable and/or preventable with anti-convulsive agents.
Patent NZ-276740-A (NZ)
Title: Stable pharmaceutical powder composition of derivatives of acetyl salicylic acid with metoclopramide (ie 4-amino-5-chloro-2-methoxy-n-(beta-diethylaminoethyl)-benzamide)
Inventor: BRU NICOLE
IPC: A61K31/60
Filed: 1994-11-25
Abstract: A novel pharmaceutical composition for the preparation of a stable powder containing an association of acetylsalicylic acid and metoclopramide as the active ingredients. The acetylsalicylic acid is in the form of a water soluble salt or complex and is in association with metoclopramide or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable hydrophilic polymer in an amount sufficient to stabilize the metoclopramide. This composition has remarkable stability in powder form and can be used to prepare sachets for the treatment of migraine.
Patent NZ-281823-A (NZ)
Title: Cyclic heptapeptide, production from streptomyces sp., use as an antiinflammatory agent
Inventor: FENICAL WILLIAM H
IPC: A61P31/04
Filed: 1995-02-16
Abstract: A cyclic heptapeptide anti-inflammatory agent named cyclomarin-A is disclosed. Cyclomarin-A is produced by a specific marine actinomycete. The cyclomarin-A producing bacterium is isolated from sediment located in marine estuaries in and around San Diego, Calif. Fermentation of the isolated bacterium in saltwater-based media produces cyclomarin-A as a secondary by-product. The cyclomarin-A is useful as an anti-inflammatory agent.
Patent NZ-286668-A (NZ)
Title: Sign-on and certificate update security for electronic money transaction modules
Inventor: ROSEN SHOLOM S
IPC: G06F19/00
Filed: 1992-10-27
Abstract: An improved monetary system using electronic media to exchange economic value securely and reliably. The invention provides a complete monetary system having electronic money that is interchangeable with conventional paper money comprising (1) issuing banks or financial institutions that are coupled to a money generator device for generating and issuing to subscribing customers electronic currency backed by demand deposits electronic credit authorizations; (2) correspondent banks that accept and distribute the electronic money; (3) a plurality of transaction devices that are used by subscribers for storing electronic money, for performing money transactions with the on-line systems of the participating banks or for exchanging electronic money with other like transaction devices; (4) automated teller devices, associated with the issuing and correspondent banks, for process handling and interfacing the transaction devices to the issuing and correspondent banks, and for interfacing between the issuing and correspondent banks themselves; and (5) a clearing bank for balancing the electronic money accounts of the different issuing banks (6).
Patent NZ-300387-A (NZ)
Title: Adenoviral vector modified to reduce host immune and inflammatory responses and its use in gene therapy treatment
Inventor: KADAN MICHAEL
IPC: A61K35/76
Filed: 1995-12-07
Abstract: An adenoviral vector comprises a modified adenoviral genome including an adenoviral 5'ITR, an adenoviral 3'ITR, an adenoviral encapsidation signal, DNA sequence encoding a heterologous protein or polypeptide and a promoter controlling the expression of the DNA sequence encoding heterologous protein or polypeptide. At least a portion of each E1 and E4 DNA sequence has been deleted to eliminate the function of each of the E1 and E4 early protein and at least a portion of at least one of the E2a and E2b DNA sequences has been deleted to eliminate the function of at least one of the E2a and E2b early protein and the vector retains at least a portion of the adenoviral protein.
Patent NZ-323647-A (NZ)
Title: Adjustable canopy
Inventor: WURZ GERALD
IPC: E04H3/16
Filed: 1996-12-06
Abstract: PCT No. PCT/AT96/00242 Sec. 371 Date Jul. 17, 1998 Sec. 102(e) Date Jul. 17, 1998 PCT Filed Dec. 6, 1996 PCT Pub. No. WO97/21014 PCT Pub. Date Jun. 12, 1997In the described awning of variable size comprising a canvas (1, 2) which can be wound up on a shaft (3) provided with a drive, the canvas (1, 2) is fastened to the shaft (3), which has only one single drive, at a parting or folding line, and for winding up or unrolling the canvas parts (1, 2) provided by the parting or folding line, at least one tensioning rope (6, 6') is provided which engages at the canvas (1, 2) and which can be coiled up on the shaft (3) on at least one coiling pulley (5, 5') seated on the shaft.
Patent NZ-331458-A (NZ)
Title: Use of 7-Adamantyl-naphth-2-yl(hetero)aryl carboxylic acids, derivatives thereof (retinoid analogues) in preparing medicaments; compounds having a polyether radical bound to a moiety of at least two carbon atoms in position-beta
Inventor: BERNARDON JEAN-MICHEL
IPC: A61K31/455
Filed: 1996-04-24
Abstract: A retinoid analogue or a salt thereof or its chiral analogues has the formula (I) wherein: R1 is methyl, CH2OH, -OR3 or -CO-R4; Ar is a radical of formula (a) to (d); R2 is a polyether radical having carbon in the position a to the carbon which is in the 6th position of the naphthyl radical; R3 is H, alkyl or -(CH2)m(CO)n-R8; R4 is H, alkyl, -N(R')(R"), or -OR9; R5 is H or halogen, alkyl, hydroxy, -OR9 or -OCOOR10; R8 is alkyl or a saturated heterocycle; R9 is H, alkyl, alkenyl, mono- or polyhydroxyalkyl, optionally substituted aryl or aralkyl or a sugar residue, amino acid or peptide residue; R10 is alkyl; R' and R" are independently H, alkyl, mono- or polyhydroxyalkyl, optionally substituted aryl, or a sugar residue, amino acid or peptide residue or together can form a saturated heterocycle and m is 1 to 3. The compound is useful in treating disorders and/or aliments related to an over-regulation of RAR receptors and/or a hypervitaminosis A.
Patent NZ-332781-A (NZ)
Title: Mouthwash composition comprising cetylpyridinium chloride and an amphoteric surfactant
Inventor: WICKS MARK ANDREW
IPC: A61K8/44
Filed: 1997-05-20
Abstract: A mouthwash composition comprising cetyl pyridinium chloride (CPC), an orally acceptable carrier or excipient and an amidobetaine of the formula:  RC(O)NH(CH2)aN+(R1)(R2)(CH2)bCO2-,wherein, R is C10-20 alkyl, R1 and R2 are C1-4 alkyl, a is an integer from 1 to 4 and b is an integer from 1 to 4.
Patent NZ-334749-A (NZ)
Title: Testing alarm system warning devices using event recorders
Inventor: MCBRIDE-WILSON ROBERT JAMES
IPC: G08B29/12
Filed: 1997-08-20
Abstract: Fire alarm and other emergency warning systems typically include annunciator devices 14 such as sounders, speakers or strobe lights and these must normally be checked for acceptable operation on a regular basis. Event recorders 20 are installed to monitor the operation of the annunciator devices of the system and the system is activated in a test to produce physical output from the devices, the physical outputs being recorded by the respective event recorders. An indication is provided by each event recorder according to the physical output of the respective device during the test.  An individual can then inspect an event recorder 20 located near to or integral with each annunciator, to check that the respective annunciator has operated correctly. Operation of the annunciator may be assessed by monitoring input or output of the annunciator, such as current levels, or audible or visible output. The outputs of the event recorders may by transmitted to a main panel via lines 50 and transponders 10.
Patent NZ-502948-A (NZ)
Title: 4-Phenyl-pyridine derivatives and use for treating diseases related to NK-1 receptor antagonists
Inventor: GALLEY GUIDO
IPC: C07D213/74
Filed: 2000-02-18
Abstract: Compounds of general formula (I) wherein: R is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl R1 is hydrogen or halogen, or R and R1 may be together -CH=CH-CH=CH- R2 and R2' are independently hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano, or R2 and R2' may be together -CH=CH-CH=CH-, optionally substituted by one or two substituents selected from lower alkyl or lower alkoxy R3 is hydrogen, lower alkyl, or form a cycloalkyl group R4 is hydrogen, -N(R5)2, -N(R5)(CH2)nOH, -N(R5)S(O)2-lower alkyl, -N(R5)S(O)2-phenyl, -N=CH-N(R5)2, -N(R5)C(O)R5 or a cyclic tertiary amine X is -C(O)N(R5)-, -(CH2)mO-, -(CH2)mN(R5)-, -N(R5)C(O)- or -N(R5)(CH2)m- n is 0-4 m is 1 or 2 Also disclosed is a process for preparing compounds of formula I and the use of the compound in treating diseases related to NK-1 receptor antagonists.
Patent NZ-507009-A (NZ)
Title: Isothiazole derivatives useful as anticancer agents
Inventor: NOE MARK CARL
IPC: C07C327/38
Filed: 1999-05-03
Abstract: Disclosed are isothiazole compounds of formula 1, wherein X1 is O or S, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for treating hyperproliferative disorders.
Patent NZ-507211-A (NZ)
Title: Sustained release preparations
Inventor: NOMURA YUKIHIRO
IPC: A61K/
Filed: 1999-03-25
Abstract: A sustained release formulation of tacrolimus or its hydrate is disclosed, wherein: the time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15 hours, as measured according to the Japanese Pharmacopoeia, 13th edition, Dissolution Test, No. 2 (Puddle method, 50 rpm) using a test solution which is an aqueous 0.005% hydroxypropyl cellulose solution adjusted to pH 4.5 which comprises: 1) a solid dispersion composition, wherein tacrolimus or its hydrate is present as an amorphous state in water-soluble base; or 2) a solid dispersion composition, wherein tacrolimus or its hydrate is present as an amorphous state in water-soluble polymer, no disintegrator is contained, and the particle size of the solid dispersion composition is equal to or smaller than 350 mm; or 3) a fine powder of tacrolimus or its hydrate which is characterised by a particle size distribution within the range of 0.1 to 50 mm and/or a mean particle diameter within the range of 0.2 to 20 mm.
Patent NZ-507454-A (NZ)
Title: Coordinated multi-axis hinge and closure using the same
Inventor: LAGLER LOUIS
IPC: B65D47/08
Filed: 1999-01-27
Abstract: A coordinated multi axis hinge arrangement provides  a snap action between stable open and closed states. When  the hinges  operate  between the stable open and  closed  states across a dead center position, resilient forces imparted  by torsionally  rigid connecting elements (33.1, 33.2)  of  the hinge  to adjacent hinge parts such as body and lid elements are  transferred  by coupling or transmitting  areas  (45.1, 45.2)  adjacent the bending regions (34.1 -  34.4)  or  film hinges to remote resilient deformation energy storage  areas (40.1  -  40.3). As the hinge passes a dead center position, this  energy is in turn supplied and returned to  the  rigid connecting  elements to impart snap action to  the  closure. The  closure  may  be  cast  as a single  piece  of  plastic material and may be cast in the open position.
Patent NZ-511397-A (NZ)
Title: Method and apparatus for secure distribution of authentication credentials to roaming users
Inventor: KAUSIK BALAS NATARAJAN
IPC: H04L29/06
Filed: 1999-11-19
Abstract: A  roaming user needing his authentication  credential (e.g.  private  key) (150) to access a web server  (110)  to perform   an   electronic   transaction   may   obtain   the authentication  credential in an on-demand  fashion  from  a credential  server  (160) accessible  to  the  user  over  a computer network. In this way, the user is free to  roam  on the   network  without  having  to  physically   carry   his authentication credential. Access to the credential  may  be protected   by  one  or  more  challenge-response  protocols involving simple shared secrets, shared secrets with one-to- one  hashing,  or  biometric  methods  such  as  fingerprint recognition.  If  camouflaging  is  used  to   protect   the authentication credential, decamouflaging may  be  performed either  at  the  credential server (160) or  at  the  user's computer (140).
Patent NZ-514716-A (NZ)
Title: Fuel cell adapter system for combustion tools
Inventor: SHKOLNIKOV YURY
IPC: F23D14/28
Filed: 2001-10-10
Abstract: A fuel cell adapter (16) configured for connection to a fuel cell (14) is disclosed.  The adapter body (18) has a cylindrical nozzle (20) and a base (22) configured for engagement upon a fuel cell (14), with the nozzle (20) connected to the base (22).   The nozzle (20) further has a passageway (26) that is provided with a fragile membrane (28) blocking the passageway (26).  The adapter body (18) included gripping formation configured for engagement with a latch.  The nozzle (20) has a plurality of lugs and a plurality of support ribs (34). Each lug (32) has a ramped configuration, extending from the free end (24) towards the base (22), and has a truncated lug end (36).   The support ribs each have a truncated rib end (38) and are configured for connecting the nozzle (20) to the base (22).  A molded insert seal (44) is housed in the passageway (26) of the adapter body (18), and defines an axial passageway (46) with a first end (48) configured for receiving a fuel cell stem (50) and a second end (52) provided with a pair of internal sealing rings (54) located in the axial passageway.
Patent NZ-521393-A (NZ)
Title: Stabilized formulations of 6-hydroxy-3-(4-[2-(piperidin-1-YL) ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene and salts thereof
Inventor: BASHORE FADIA NAJJAR
IPC: A61P25/28
Filed: 2001-04-30
Abstract: A pharmaceutical formulation comprising 6-hydroxy-3- (4-[2-(piperidin-1-yl) ethoxy] phenoxy) -2-(4-methoxyphenyl) benzo [b] thiophene or a salt thereof, stabilised to oxidation or other forms of decomposition by incorporation of a stabilising agent selected from methionine, acetylcysteine, cysteine or salts thereof. The method of the said stabilisation is also discussed. The pharmaceutical formulation is described as being useful in the preparation of a medicament for inhibiting a wide range of pathological conditions including cancers such as breast or prostate cancer, cardiovascular disease and Alzheimer's disease.
Patent NZ-522009-A (NZ)
Title: Trap
Inventor: DRAPER ROY ALAN
IPC: A01M23/32
Filed: 2001-03-15
Abstract: Animal trap (10) comprises at least one base member (12) for contact with ground, at least one frame member (18) pivotally arranged with respect to at least one base member (12) and release mechanism (30) for holding, in use, at least one frame member (18) under tension above ground. Netting (54) attached to at least one frame member (18) so that when release mechanism (30) is tripped by animal (56) entering trap (10), at least one frame member (18) pulls netting (54) over animal (56) as at least one frame member (18) falls to ground when tension is released.
Patent NZ-536461-A (NZ)
Title: Methods for identifying and using amyloid-inhibitory compounds
Inventor: FRAIL DONALD E
IPC: A61P25/24
Filed: 2000-11-03
Abstract: A method for predicting an increased likelihood of amyloidosis comprising measuring the level of estrogen in a sample obtained from a subject and comparing the measured level against either a normal level or a level of estrogen taken from the subject at an earlier time, then determining whether there is an increased likelihood of amyloidosis based upon a decrease in the level of an estrogen compound observed in the sample. The method can be used to predict an increased likelihood of developing Alzheimer's disease. (62) Divided out of 518780
Patent NZ-539508-A (NZ)
Title: Substituted benzoxazinones and uses thereof
Inventor: MAAG HANS
IPC: C07D265/36
Filed: 2003-11-04
Abstract: Disclosed is a compound of formula I wherein: Y is C or S; m is 1 when Y is C and 2 when Y is S; n is 1 or 2; p is from 0 to 3; q is from 1 to 3; Z is -(CRaRb)r- or -SO2-, where each of Ra and Rb is independently H or alkyl; r is from 0 to 2; X is CH or N; each R1 is as defined in the specification; R2 is an optionally substituted aryl or heteroaryl as defined in the specification; and each of R5-R9 is independently H or alkyl, or one of R5 and R6 together with one of R7, R8 and R9 and the atoms therebetween my form a ring of 5-7 members. Compounds of the type disclosed are 5-hydroxytryptamine modulators useful in the treatment of central nervous system and gastrointestinal diseases.
Patent NZ-541625-A (NZ)
Title: Partition bus for providing integration between partitions in a virtual machine environment
Inventor: OSHINS JACOB
IPC: G06F9/46
Filed: 2005-08-03
Abstract: A system for providing integration between partitions in a virtual machine environment includes a first and second partition and a transfer mechanism. The transfer mechanism allows for the transferring of information between the first and second partition by using at lest one of i) a ring buffer, and ii) any one of a transfer page and an address space manipulation.