baber/WOPTO huggingface dataset:
Patent JP-3739143-B2 (JP)
IPC: C12N15/52
Filed: 1996-09-03
Granted: 2006-01-25
Abstract: Provided is an industrially applicable process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Dactylosporangium, Amycolatopsis or Streptomyces and which catalyzes the hydroxylation of L-proline into trans-4-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced trans-4-hydroxy-L-proline is collected from the aqueous medium. Also provided is a novel transformant containing a gene, coding for L-proline-4-hydroxylase and having a reinforced L-proline biosynthesis activity. In addition, provided is a process for producing L-proline-4-hydroxylase using the transformant which contains the gene and has a reinforced proline biosynthesis activity.
Patent JP-H0742090-B2 (JP)
IPC: D21C9/14
Filed: 1991-08-27
Abstract: A process for the production of chlorine dioxide by reacting in a reaction vessel an alkali metal chlorate, mineral acid and a reducing agent in such proportions that chlorine dioxide is produced in a reaction medium which is maintained at a temperature of from about 50 DEG C to about 100  DEG C and at an acidity within a range of from about 2 to about 5 N. The reaction medium is subjected to subatmospheric pressure sufficient for evaporating water, a mixture of chlorine dioxide, oxygen and water vapour being withdrawn from an evaporation zone in the reaction vessel, and alkali metal sulfate being precipitated in a crystallization zone in the reaction vessel. As the reducing agent hydrogen peroxide is used.
Patent JP-H0449279-B2 (JP)
IPC: H05K9/00
Filed: 1984-11-14
Abstract: The disclosure relates to improved system grounding that includes two system grounding paths for card caged electronic modules. A grounding path through the card cage and a grounding path through the system power supply are used to minimize noise, i.e., reduce unwanted induced superimposed transient voltage levels.
Patent JP-2647454-B2 (JP)
IPC: F16K31/44
Filed: 1988-10-07
Granted: 1997-08-27
Abstract: A top cartridge for an individual, sanitary, dual-control, shut-off valve is provided. The cartridge includes an upper stationary and a lower rotatable disk, each disk including port apertures. The disks are arranged with a defined clearance in the longitudinal direction of a driver pin. A driver is welded to the pin and includes a finger which engages the rotatable disk. The upper end of the pin is pressed within a spindle. The spindle is positioned within a bushing to prevent calcination and corrosion thereof. A seal is provided near the bottom end of the pin between the driver and the rotatable disk.
Patent JP-2934005-B2 (JP)
IPC: B41M5/145
Filed: 1990-09-27
Granted: 1999-08-16
Abstract: Pyran-containing phthalides of the formula   <IMAGE> (1)  in which R is hydrogen, alkyl which has not more than 12 carbon atoms and is unsubstituted or substituted by halogen, cyano, hydroxyl or lower alkoxy, or is cycloalkyl, phenalkyl or phenyl each of which is unsubstituted or substituted, or an unsubstituted or substituted heterocyclic radical, R' is hydrogen, or R together with R' is C2-C3alkylene which is unsubstituted or substituted by methyl, X is hydrogen, alkyl having 1 to 12 carbon atoms or a monocyclic or polycyclic aromatic or heteroaromatic radical and the ring A is a benzene or naphthalene ring which is unsubstituted or monosubstituted or polysubstituted by halogen, lower alkyl, lower alkoxy or lower alkoxycarbonyl, and the ring B is an aromatic or heteroaromatic radical which has 6 ring atoms and which can contain an aromatic fused ring, it being possible for both the ring B and the fused ring to be substituted. These phthalides are particularly suitable for use as color-formers in pressure-sensitive or heat-sensitive recording materials and produce light-fast, orange, red, violet, green-blue, blue or violet-blue color shades.
Patent JP-2604540-B2 (JP)
IPC: B65B3/00
Filed: 1993-10-13
Granted: 1997-04-30
Abstract: A system for dispensing liquid food products is disclosed. The product is drawn from a source (6) to a metering chamber (20) through a supply valve (10), and then conducted to a dispensing valve (24) to fill preformed containers. The valves have a valve stem (45) that reciprocates to open and close the valve. The valve stem is supported in the passage through which the product flows by bearings. The bearings have balls (52) that engage the stem (45) and the wall of the passage (46). The use of balls to support the stem facilitates cleaning of the passage after use, and yet provides good support for the valve stem. <IMAGE>
Patent JP-2799865-B2 (JP)
IPC: C07F7/18
Filed: 1988-11-04
Granted: 1998-09-21
Abstract: Fluorinated arachidonic derivatives are 5-lipoxygenase inhibitors which have the useful pharmacologic activity as antiallergy and anti-inflammatory agents and are useful for treating, for example, asthma, anaphylaxis, allergy, rheumatoid arthritis, and psoriasis.
Patent JP-3299792-B2 (JP)
IPC: A61B/
Filed: 1992-10-08
Granted: 2002-07-08
Abstract: An electrosurgical device for laparoscopic use in tissue dissection and coagulation. The device includes a barrel member having a dissection tip at the distal end thereof that is connected to a source of electrical energy. An insulating sheath member surrounds the barrel member. The sheath member is movable between a first position wherein the distal end thereof extends distally beyond the dissection tip and a second position wherein the dissection tip extends distally beyond the distal end portion of the sheath member. The device includes means to flush and vacuum the surgical site. The device also includes pressure relief means (106-108) to limit the internal pressure within the device.
Patent JP-3131215-B2 (JP)
IPC: A61P3/08
Filed: 1990-11-05
Granted: 2001-01-31
Abstract: Insulin derivatives of the formula III 
<IMAGE>
 in which 
 
  a) R<30> + R<31> together = OH or 
  b) R<30> = residue of a neutral, genetically encodable L-amino acid and R<31> = OH or
 a physiologically acceptable organic group which is basic in nature and has up to 50 C atoms, in whose structure 0 to 3  alpha -amino acids are involved and whose optionally present terminal carboxyl group can be free, in the form of an ester, of an amide or of a lactone, or reduced to CH2OH, and 
  c) R<A-1> = residue of a genetically encodable L-amino acid or a physiologically acceptable organic group with up to 50 C atoms, with the exception of the cases in which simultaneously R<30> = Ala, R<31> = OH, R<A-1> = Lys or Arg, and the A chain and B chain are the sequences of bovine insulin, 
 and the physiologically tolerated salts thereof. 
<??>The compounds are suitable for the treatment of diabetes mellitus, have a delayed action profile and are very well tolerated.
Patent JP-3523733-B2 (JP)
IPC: F24F11/76
Filed: 1995-11-28
Granted: 2004-04-26
Abstract: PROBLEM TO BE SOLVED: To make it possible to eliminate the shortage of a cooling capacity during overload operation by detecting a room temperature during overload operation and increasing the rotary speed of a fan when a specific setting conditions are satisfied for a specified time. SOLUTION: In a freezing cycle where an indoor heat exchanger, a pressure reduction device and an outdoor heat exchanger, which are cooled with a compressor, a four-way valve and an indoor fan 4, are connected one by another, there is provided a room temperature detector 9 while a first setting temperature memory means 21 is provided, which stores the setting temperature set by a temperature setting device 10. When a first comparison means 23 detects that the detected room temperature exceeds the setting temperature and a second comparison means 24 detects that the setting temperature level fails to exceed the specified value, a clock means 25 is adapted to start counting the time. Then, in the case where a determination means 27 determines that this clock time has reached a specified time, the rotary speed of an indoor fan 4 is increased.
Patent JP-3585253-B2 (JP)
IPC: B29C65/48
Filed: 1993-12-24
Granted: 2004-11-04
Abstract: PURPOSE:To simultaneously perform modification and bonding regardless of the region and diameter of a resin tube by interposing an adhesive and/or a compd. having functional group showing compatibility with respect to the tube between the resin tube and an article to be bonded and irradiating the tube with laser or ultraviolet rays of specific energy to bond the tube and the article to be bonded. CONSTITUTION:An adhesive and/or a compd. having a functional group showing compatibility with respect to the tube is interposed between the inner or outer wall of a resin tube and an article to be bonded and the tube is irradiated with laser or energy beam containing ultraviolet rays with photon energy of 80kcal/md or more from the exterior or interior or both of the interior or exterior thereof to chemically bond the tube and the adhesive and/or the compd. having the functional group showing compatibility with respect to the adhesive to bond the tube and the article to be bonded. That is, laser beam passes through a light path 7 and a mirror 2 from an excimer device 1 to be guided to a sample 3 and reaches the adhesive while it is absorbed into the resin tube 4 and the adhesive is cured to bond the tube 4 and the article 5 to be bonded.
Patent JP-3507111-B2 (JP)
IPC: A61C8/00
Filed: 1993-12-06
Granted: 2004-03-15
Abstract: The invention relates to a method and device for preparing implant surfaces of metallic or ceramic material, preferably titanium, using gas-discharge plasma with the aim of obtaining a well-defined and reproducible implant surface. After machining and any washing procedures which may be necessary, the implants (2) are conveyed to a vacuum chamber (K2) in which the plasma preparation is carried out in two steps. Firstly, a treatment with an inert gas plasma is effected so that existing surface contamination layers and oxide layers are removed from the implant. A reoxidation is then effected using an oxidizing plasma or by means of thermal oxidation. The plasma preparation and any remaining preparation steps which may be necessary, and handling of the implants (2), are carried out in accordance with a closed procedure without intermediate exposure to uncontrolled environmental atmospheres. In this way, a higher grade of controlled surface characteristics and reproducibility is obtained for the surface of the implant as compared with previously used methods. The properties of the plasma-prepared surface can be preserved right up to the moment of use.
Patent JP-4602499-B2 (JP)
IPC: C08G18/79
Filed: 1999-12-03
Granted: 2010-12-22
Abstract: Lacquer preparations in which the solid lacquer contains 40-100 wt.% specified alkoxysilyl-functional polyisocyanate-polyurea are new. The lacquer preparations in which the solid lacquer contains 40-100 wt.% alkoxysilyl-functional polyisocyanate-polyurea are prepared from: (A) a polyisocyanate (mixture) containing at least 50 wt.% of 4,4-diisocyanateodicyclohexylmethane polyisocyanates, having a mean NCO-functionality of 2.5-5.5, an isocyanate group content of 11.0-20.0 wt.%, and a diisocyanate monomer content of less than 10 wt.%; (B) at least 0.7 equivalents (with respect to isocyanate groups) of aminosilanes of formula (I): (RO)nY(3-n)Si-CH2CH2CH2-NHZ (I) where: R = Me, or Et; Y = Me; Z = H, 1-12C alkyl, CH2CH2CH2-Si(RO)nY(3-n); n = 1-3; and (C) optional other compounds reactive to isocyanate groups. Independent claims are included for: (1) lacquer preparations containing 20-50 wt.% on the solid lacquer of silane of formula (II): QSi(OX)3 (II) where: X = Me, Et, isopropyl, Bu; Q = H, 1-8C alkyl, phenyl, methoxy, ethoxy, 3-glycidyoxy-propyl or a hydrolyzate/condensate obtained from it; (2) a lacquer preparation based on (A) to (C) above consisting of a sol-gel lacquer system.
Patent JP-3416547-B2 (JP)
IPC: C22B1/16
Filed: 1998-12-28
Granted: 2003-06-16
Abstract: A process for preparing high carbon content briquettes includes providing a particulate material which includes iron particles including iron oxide in an amount of at least about 4% based on weight of the material, and carbon particles in an amount greater than about 2% based on weight of the material; and subjecting the material to briquetting temperature and pressure so as to provide stable agglomerate briquettes of the material.
Patent JP-2801082-B2 (JP)
IPC: D06F11/00
Filed: 1989-12-27
Granted: 1998-09-21
Abstract: PCT No. PCT/FI89/00241 Sec. 371 Date Jun. 27, 1991 Sec. 102(e) Date Jun. 27, 1991 PCT Filed Dec. 27, 1989 PCT Pub. No. WO90/07604 PCT Pub. Date Jul. 12, 1990.A machine for washing carpets having a frame, a plurality of elongated rolls located in the frame for transferring the carpet through the machine, and a distributing unit mvoable along the length of the rolls for spraying cleaning solution on the carpet. The machine also includes hoses connected at one end to the distributing unit, and at the other end, to a transportation device. The transportation device is movable, which moves the hoses, which in turn moves the distributing unit along the length of the rolls.
Patent JP-3751018-B2 (JP)
IPC: G06F11/14
Filed: 1994-06-02
Granted: 2006-03-01
Abstract: The present invention provides a method for keeping a file system in a consistent state and for creating read-only copies of a file system. Changes to the file system are tightly controlled. The file system progresses from one consistent state to another. The set of self-consistent blocks on disk that is rooted by the root inode is referred to as a consistency point. To implement consistency points, new data is written to unallocated blocks on disk. A new consistency point occurs when the fsinfo block (2440) is updated by writing a new root inode for the inode file (1210) into it. Thus, as long as the root inode is not updated, the state of the file system represented on disk does not change. The present invention also creates snapshots (Figure 22) that are read-only copies of the file system. A snapshot uses no disk space when it is initially created. It is designed so that many different snap shots can be created for the same file system. Unlike prior art file systems that create a clone by duplicating the entire inode file and all of the indirect blocks, the present invention duplicates only the inode that describes the inode file. A multi-bit free-block map file (1630) is used to prevent data from being overwritten on disk.
Patent JP-2556197-B2 (JP)
IPC: H04W88/18
Filed: 1990-02-07
Granted: 1996-11-20
Abstract: A paging system comprising a centrally located terminal and a plurality of remote pager units is disclosed wherein both automatic and manual acknowledge back signalling is provided. An appropriate acknowledge back signal by a called pager within a set interval indicates the message was duly receivied and understood which is so indicated to the initiating caller. Failure to respond within the set interval causes the pager unit to send back a negative response which is likewise so indicated to the initiating caller.
Patent JP-2930218-B2 (JP)
IPC: A61J11/02
Filed: 1990-02-08
Granted: 1999-08-03
Abstract: PCT No. PCT/FR90/00123 Sec. 371 Date Oct. 9, 1990 Sec. 102(e) Date Oct. 9, 1990 PCT Filed Feb. 8, 1990 PCT Pub. No. WO90/09161 PCT Pub. Date Aug. 23, 1990.The variable-flow feeder (1) of the invention is meant to be fitted in particular onto a milk bottle and comprises at the end of its nipple (2) a slit (3) with two arms (3a, 3b) subtending between them an angle, and is characterized in that the angle subtended by the two arms of the slit (3) is an obtuse angle GAMMA  between 165 DEG  and 95 DEG  of which the vertex lies on the feeder axis, in that the lengths l1 and l2 (l1>l2) of the slit arms form such a ratio l1/l2 that it falls between a value of 1 and  delta , the value of  delta  increasing from 1 to 10, preferably from 1 to 4.5, when the angle  GAMMA  decreases from 165 DEG  to 95 DEG , said arms of the slit (3) being determined by cutting lines which do not remove material and issuing at their non-adjacent ends into a hole (4b, 4c) of small cross-section.
Patent JP-3138871-B2 (JP)
IPC: G06F21/10
Filed: 1997-06-27
Granted: 2001-02-26
Abstract: A software product is modified so that it can be freely distributed while limiting its use to authorized subscribers. The modification includes replacing calls to relocatable subroutines in the software product by calls to redirection software, which is added to the software product together with authorizing software. A table of information on the replaced calls is supplied securely to an authorization agent, with which the authorizing software communicates on execution of the modified software product. An authorized subscriber supplies local data specific to its environment to the authorization agent, which encodes the table in dependence upon the local data and the authorizing software and supplies it to the authorized subscriber. Tampering with the authorizing software, or different local data of others, prevents use of the table. The redirection software decodes a target address for each replaced call during execution of the software, without decoding of the table or restoring the software to its original form. Alternatively, the redirection software can be supplied to the authorized subscriber by the authorization agent.
Patent JP-2553686-B2 (JP)
IPC: G03B42/02
Filed: 1988-05-09
Granted: 1996-11-13
Abstract: PCT No. PCT/EP88/00404 Sec. 371 Date Nov. 8, 1989 Sec. 102(e) Date Nov. 8, 1989 PCT Filed May 9, 1988 PCT Pub. No. WO88/09003 PCT Pub. Date Nov. 17, 1988.Cassette centering device for an X-ray cassette loading and unloading device using two parallelly movable guides engageable with the side edges of the cassette, the guides being movable by a lever arrangement driven by a motor, the lever arrangement including a link having two telescoping parts and biasing means constituting force absorbing means for cushioning the engagement of the guides with the cassette and compensating for motor overdrive.
Patent JP-3117083-B2 (JP)
IPC: C12Q1/68
Filed: 1989-05-18
Granted: 2000-12-11
Abstract: A process for determining the genotype of an individual with respect to the alleles at the HLA DP locus involves obtaining a sample of nucleic acid from the individual, and hybridizing the nucleic acids with a panel of probes specific for variant segments of DPalpha and DPbeta genes. Because the variation between DPbeta alleles is highly dispersed throughout the second exon of the DPbeta gene, the discovery of many different DPbeta alleles makes the process far more discriminating and informative than cellular, RFLP, or serological methods. The process can also be carried out on amplified nucleic acid produced by the polymerase chain reaction using primers specific for the second exon of the DPalpha and DPbeta genes. HLA DP DNA typing methods are useful in the prevention of graft rejection and host versus graft disease, in determining susceptibility to autoimmune diseases, in providing evidence concerning the derivation from an individual of forensic samples, and in paternity testing.
Patent JP-3704349-B2 (JP)
IPC: A61M5/24
Filed: 1994-08-08
Granted: 2005-10-12
Abstract: The disclosure relates to a syringe with a protector case which holds a glass carpule and permits the injection of the fluid contained in the carpule into the patient. The syringe is molded of plastic or other suitable material which is sterilizable. The device comprises seven parts including a body, protector case, needle, needle cap, plug, plunger and harpoon. The major components of the device preferably are molded from a suitable plastic and may be clear or of a color like or similar to a surgical glove.
Patent JP-3987571-B2 (JP)
IPC: A61L33/00
Filed: 1994-08-29
Granted: 2007-10-10
Abstract: An intravascular medical device having a structure shaped and sized for introduction into the vascular system of a patient including a base material and a coating of a thrombolytic agent on the base material. The thrombolytic agent advantageously dissolves or breaks up the formation of thrombus on the surface of the structure when placed in the vascular system of a patient. The intravascular medical device also includes a antithrombogenic agent for inhibiting the formation of thrombus on the surface of the medical device. The method of treating a medical device with a thrombolytic agent includes providing a base material for the medical device along with a thrombolytic agent. The base material is dipped into the thrombolytic agent and then removed to allow the thrombolytic agent to dry on the surface thereof. The dipping and drying steps are repeated to increase the concentration or quantity of the thrombolytic agent on the device.
Patent JP-3258666-B2 (JP)
IPC: A61K31/58
Filed: 1994-07-29
Granted: 2002-02-18
Abstract: PCT No. PCT/EP94/02531 Sec. 371 Date Jul. 15, 1996 Sec. 102(e) Date Jul. 15, 1996 PCT Filed Jul. 29, 1994 PCT Pub. No. WO95/08323 PCT Pub. Date Mar. 30, 1995Disclosed are budesonide pellets with a controlled release pattern containing, from the inside to the outside: a) neutral pellets; b) an active principle layer of micronized budesonide and one or more water-soluble auxiliaries; c) a first lacquer coating consisting of 80 to 97% of at least one lacquer insoluble in gastric fluids but soluble in intestinal fluids and 3 to 20% of at least one lacquer insoluble in both gastric and intestinal fluids; and d) a second lacquer coating consisting of at least one lacquer insoluble in gastric and intestinal fluids. The invention also relates to a process for producing budesonide pellets with a controlled release pattern.
Patent JP-3073212-B2 (JP)
IPC: C12Q1/68
Filed: 1989-08-31
Granted: 2000-08-07
Abstract: Peptides and proteins related to an epitope comprising an outer membrane protein of Haemophilus influenzae are described. The peptides and proteins can be prepared by methods including novel and improved methos of purification from H. influenzae cultures, and by recombinant DNA and chemical synthetic techniques. Additionally, recombinant vectors containing nucleotide sequences encoding PBOMP-1 and PBOMP-2 related peptides, proteins and fusion proteins are also described. Recombinant vectors include plasmid DNA and viral DNA such as human viruses, animal viruses, insect viruses and bacteriophages that direct the expression of the PBOMP-1 and PBOMP-2 related peptides, proteins, and fusion proteins in appropriate host cells. The peptides, proteins, fusion proteins and viruses both ''live'' and ''inactivated'' are used as immunogens in vaccine formulations to protect against H. influenzae infections. The peptides, proteins and fusion proteins are also used as reagents in immunoassays as well as to prepare immunoglobulins for passive immunization. Use of the nucleotide sequences encoding the PBOMP related peptides, proteins and fusion proteins in hybridization assays is also described.
Patent JP-4262308-B2 (JP)
IPC: A61K38/00
Filed: 1996-09-13
Granted: 2009-05-13
Abstract: Red blood cells can be loaded with low molecular weight nitrosylating agents, such as S-nitrosothiols, to act as a delivery system for NO<SUP>+</SUP> groups to tissues. Loaded red blood cells can be used in methods of therapy for conditions which are characterized by abnormal O<SUB>2 </SUB>metabolism of tissues, oxygen-related toxicity, abnormal vascular tone, abnormal red blood cell adhesion, or abnormal O<SUB>2 </SUB>delivery by red blood cells. Such treatment of red blood cells can be extended to in vivo therapies, with the object to achieve an increase in the ratio of red blood cell S-nitrosothiol to hemoglobin.