baber/WOPTO huggingface dataset:
Patent CA-2491754-A1 (CA)
Inventor: WU JAMES B C
IPC: C22C19/07
Filed: 2003-06-16
Abstract: La présente invention concerne un alliage à base de Co comprenant 13-16 % en poids de Cr, 20-30 % en poids de Mo, 2,2-3,2 % en poids de Si, le reste étant du Co, et le rapport Cr:Si valant entre environ 4,5 et environ 7,5, le rapport Mo:Si valant entre environ 9 et environ 15, ledit alliage étant résistant à l'usure et à la corrosion à la fois dans des acides oxydants et dans des acides réducteurs.
Patent CA-2491999-A1 (CA)
Title: Appareil et procede de manipulation et d'enrobage automatique d'echantillons de tissus
Inventor: HUDDLESTON MATTHEW J
IPC: G01N1/36
Filed: 2002-09-26
Abstract: L'invention concerne une machine automatique (10) de manipulation et d'enrobage d'échantillons (210) de tissus placés sur des supports de microtome sectionnables. La machine (10) comprend un élément (100) d'entrée configuré pour recevoir une pluralité de supports de microtome sectionnables (150a) avant une opération d'enrobage de tissu. Un élément (32a-32d) est configuré pour recevoir une pluralité de supports de microtome sectionnables (150a) après une opération d'enrobage de tissu. Une unité (80) de refroidissement est configurée pour recevoir au moins un des supports de microtome sectionnables (150a) au cours de l'opération d'enrobage du tissu. Un ensemble (40) de transport motorisé est monté pour être déplacé et configuré pour recevoir au moins un des supports de microtome sectionnables (150a). L'ensemble (40) de transport déplace le support (150a) de l'élément (100) d'entrée vers l'unité (80) de refroidissement et, enfin, vers l'élément ( 32a-32d) de sortie. Un dispositif (212) de distribution distribue un matériau (205) d'enrobage sur le support de microtome sectionnable (150a) et au moins un échantillon (210) de tissu porté par le support de microtome sectionnable (150a) au cours de l'opération d'enrobage.
Patent CA-2497499-A1 (CA)
Title: Use of malate dehydrogenase for nadh regeneration
Inventor: HUMMEL WERNER
IPC: C12P7/40
Filed: 2003-08-05
Abstract: The present invention relates to a process for the preparation of enantiomerically enriched organic compounds. In particular, the present invention relates to an enzymatically operating process, in which, in a coupled enzymatic reaction system, NAD(P)H is consumed by one enzyme for the preparation of the organic compound and the NAD(P)H is simultaneously regenerated by a second enzyme system. A reaction system which operates according to the invention in this manner and an advantageous whole cell catalyst are also proposed.
Patent CA-2497589-A1 (CA)
Inventor: WIESEL JEFFREY M
IPC: H01P1/12
Filed: 2005-02-18
Abstract: A microwave switch housing assembly for operation in a selected frequency range. The housing assembly includes a housing having ports, a rotor containing at least one waveguide passage, and power absorbing material positioned either in the housing or in the rotor. Ports are positioned within the housing it so that in a first position of the rotor, the waveguide passage connects the ports and in a second position of the rotor, the waveguide passage is unconnected to the ports. The power absorbing material is positioned adjacent to one end of said waveguide passage when said rotor is in said second position it absorbs electromagnetic energy in the frequency range and reduces the tendency of the isolation passage to act as a volume resonator when the rotor is in the second position.
Patent CA-2498210-A1 (CA)
Inventor: YU CHUNRONG
IPC: A61K31/165
Filed: 2003-09-10
Abstract: L'invention concerne une combinaison d'un inhibiteur de l'histone déacétylase et de N-Ý5-Ý4-(4méthyl-pipérazino-méthyl)-benzoylamido¨-2-méthylphényl}-4-(3-pyridyl)-2-pyrimidine ou d'un sel pharmaceutiquement acceptable de ce dernier en vue de son utilisation simultanée, séparée ou ou séquentielle dans le traitement de la leucémie, en particulier la leucémie résistant à N-Ý5-Ý4-(4méthyl-pipérazino-méthyl)-benzoylamido¨-2-méthylphényl}-4-(3-pyridyl)-2-pyrimidine.
Patent CA-2499304-A1 (CA)
Title: Self-expanding defect closure device
Inventor: SHAW EDWARD E
IPC: A61M25/01
Filed: 1999-06-10
Abstract: The present invention relates to a self-expanding device for sealing a defect in a wall, such as a septal defect. The device of the present invention has a helical shaped periphery formed from an elastic wire and at least one eyelet. The eyelet has a non-circular ("asymmetric") shape which allows the eyelet to slide along a guiding mandrel. The non-circular shaped eyelet and mandrel prevent rotation of the eyelet relative to the mandrel thereby ensuring a consistent deployed shape. The present invention also incorporates a self-articulating catheter tip which can be bent to a variety of angles to enhance the ease of delivery. The tip is articulated by varying the position of the closure device within the articulated portion of the catheter.
Patent CA-2502301-A1 (CA)
Inventor: PALGEN MARIE-CLAUDE
IPC: B60C9/28
Filed: 2003-10-09
Abstract: The tire, having radial carcass and crown reinforcement, the latter comprising at least two continuous layers (15, 16) made from elements that overlap at an angle of 10 - 35 deg to one another. The crown reinforcement is completed by at least three half-layers (17, 18, 19) on each side of the circumferential median plane, with their elements lying at angles of 10 - 40 deg to the circumferential direction. The tire, having radial carcass and crown reinforcement, the latter comprising at least two continuous layers (15, 16) made from elements that overlap at an angle of 10 - 35 deg to one another. The crown reinforcement is completed by at least three half-layers (17, 18, 19) on each side of the circumferential median plane, with their elements lying at angles of 10 - 40 deg to the circumferential direction. The half-layer that extends furthest outwards is in contact with at least two other half layers, and the three half-layers cover the outer axial edges of at least two continuous crown reinforcing layers (15, 16). The continuous layers are the closest radially to the carcass reinforcement, with the narrowest of the continuous layers being the closest to the outer radial layer of the carcass reinforcement. Both the continuous crown reinforcement and half-layers are made from non-stretch metal cables, and the crown reinforcement is completed by at least two protective layers (22, 23) of elastic metal elements.
Patent CA-2505419-A1 (CA)
Inventor: VARGAS-VORACEK RENE
IPC: G06T7/00
Filed: 2003-11-25
Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.
Patent CA-2509214-A1 (CA)
Title: Indolizine compounds
Inventor: CHIMMANAMADA DINESH
IPC: C07D471/04
Filed: 2003-12-10
Abstract: This invention relates to compounds of Formula (I) wherein Ring A, X, Y, Z, R1, R2 and R3 are defined herein. These compounds are useful for treating and preventing cancer, inflammatory disorders, autoimmune diseases and other conditions involving PDE4 or elevated levels of cytokines. This invention also relates to pharmaceutical compositions comprising at least one compound of Formula (I) and methods for treating and preventing cancer, inflammatory disorders, autoimmune diseases and other conditions involving PDE4 or elevated levels of cytokines.
Patent CA-2509830-A1 (CA)
Title: Pharmaceutical compositions of sertaconazole for vaginal use
Inventor: ROMERO ALFONSO
IPC: A61K9/00
Filed: 2003-12-17
Abstract: The invention relates to monodose mucoadhesive vaginal compositions of sertaconazole or a pharmaceutically acceptable salt thereof for the treatment of vulvovaginal candidiasis.
Patent CA-2511636-A1 (CA)
Inventor: CATTACIN GILLES
IPC: B65H75/18
Filed: 2005-07-06
Abstract: The invention relates to a system of dispensing a product rolled around an element such as a tube (50), such product defining a structure such as a cylinder, and such system comprising in particular: a frame, a means of support and connection of the roll in the frame. It is claimed for the invention that the tube (50) includes an electrically conductive element (50c) designed to operate in conjunction with an element of the frame so as together to form an electric circuit element.
Patent CA-2515829-A1 (CA)
Inventor: BLAIS DANIEL
IPC: B63C9/02
Filed: 2005-08-11
Abstract: A rescue boat capable of use on ice, strewn water, water, snow and dragged over rigid surfaces is described. The rescue boat comprises a hull fabricated from a lamination of fiber materials having a specific orientation to provide flexibility for shock absorbing. An inner keel beam is retained along a central longitudinal axis of the hull on an inner surface of the hull. A transom cowling extends across opposed sidewalls of the hull and merges into a transom wall laminated with the hull. One or more transverse seating frames are secured across the opposed sidewalls by connecting brackets and adapted to transfer impact forces with the sidewalls. One or more vertical rigid support posts are secured to the inner keel beam and an associated one of the one or more transverse seating frames for transmitting vertical impact forces between the inner keel beam and the one or more transverse seating frames.
Patent CA-2518514-A1 (CA)
Inventor: BISSON DIDIER
IPC: H01R25/16
Filed: 2004-03-01
Abstract: The invention relates to a system in which the support piece (2) comprises a stud (3) which is designed to be engaged in a hole (4) in the conductor (1) and to co-operate with a hold-down nut (5) for clamping the conductor to said support piece. The invention is characterised in that an electrically-conductive ring spacer (6) is associated with the conductor (1) on the side thereof facing the support piece (2). The invention is also characterised in that a ring (7) is disposed on the opposite side of the conductor. Moreover, the ring (7) comprises floating means (7a, 7b) for fixing to the spacer (6), which are designed to extend through the aforementioned hole (4) in the conductor. The invention is further characterised in that the above-mentioned nut (5) is associated with the ring (7) using fixing means (5a, 5b) which enable the nut (5) to rotate in relation to the ring (7) and to move axially in relation to same along a determined length of travel, between a mounting position at a distance from the ring and a clamping position in which the nut rests against said ring, in order to facilitate the positioning of the conductor (1) and the clamping of same against the support piece (2).
Patent CA-2524640-A1 (CA)
Title: 2, 3, 4, 5-tetrahydrobenzo[f][1,4]oxazepine-5-carboxylic acid amide derivatives as gamma-secretase inhibitors for the treatment of alzheimer's disease
Inventor: GALLEY GUIDO
IPC: A61K31/553
Filed: 2004-05-14
Abstract: The invention relates to benzoxazepinone derivatives of formula (I) wherein R1 is hydrogen, lower alkoxy, halogen or -NR'R"; n is 1 or 2; R',R" are independently from each other hydrogen or lower alkyl; R2 is hydrogen, lower alkyl, -(CH2)m-cycloalkyl, -(CH2)m-phenyl or -(CH2)m-O-lower alkyl; m is 0,1or 2; R3 is lower alkyl, -(CH2)m-C(O)O-lower alkyl, cycloalkyl or -(CH2)m-phenyl, which is unsusbtituted or substituted by one or two substituents, selected from the group consisting of halogen or lower alkyl; R4 is -(CH2).omicron.-phenyl, which is unsusbtituted or substituted by one or two substituents, selected from the group consisting of halogen, trifluoromethyl, -NR'R", nitro or_SO2NH2, or is - cycloalkyl, unsubstituted or substituted by phenyl, or is -(CR'R").omicron.-heterocyclyl, selected from the group defined in claim 1 and o is 1 or 2; and to pharmaceutically suitable acid addition salts thereof.  These compounds are good .gamma.-secretase inhibitors for the treatment of Alzheimer's disease.
Patent CA-2525228-A1 (CA)
Title: Molecules enhancing dermal delivery of influenza vaccines
Inventor: JIANG GE
IPC: A61K31/716
Filed: 2004-05-12
Abstract: The present invention relates to dermal vaccine formulations, designed for targeted delivery of an immunogenic composition to a dermal compartment of skin including the intradermal and epidermal compartments. The dermal vaccine formulations of the invention comprise an antigenic or immunogenic agent, and at least one molecule, e.g., a chemical agent, which enhances the presentation and/or availability of the antigenic or immunogenic agent to the immune cells of the intradermal compartment or epidermal compartment resulting in an enhanced immune response. The dermal vaccine formulations of the invention have enhanced efficacy as the antigenic or immunogenic agent is delivered to the intradermal compartment or epidermal compartment with enhanced presentation and/or availability to the immune cells that reside therein. The enhanced efficacy of the dermal vaccine formulations results in a therapeutically effective immune response after a single intradermal or epidermal dose, with lower doses of antigenic or immunogenic agent than conventionally used, and without the need for booster immunizations.
Patent CA-2526873-A1 (CA)
Title: Film layers made from ethylene polymer blends
Inventor: DEKUNDER STACI A
IPC: C08J5/18
Filed: 2004-06-02
Abstract: Film layers made from formulated ethylene polymer compositions are disclosed.  Film layers made from such formulated compositions have surprisingly good heat seal properties, and an especially good reduction in heat seal initiation temperature. The ethylene polymer compositions have at least one homogeneously branched ethylene/alpha-olefin interpolymer and at least one homogeneously or heterogeneously branched ethylene polymer which has a lower melt index than the first mentioned component. The first homogeneously branched ethylene/alpha-olefin interpolymer has a melt index higher than that of the formulated composition.
Patent CA-2530009-A1 (CA)
Inventor: MCCLEARY JOSEPH F
IPC: A01G1/12
Filed: 2005-12-13
Abstract: Various systems and methods for material sorting are described. As one example, a system for sorting materials is described that includes a material handler mounting component that is tailored for connection to a material handler. In addition, the system includes a cross conveyor that is connected to the material handler mounting component. An elevation adjustment device is connected to the cross conveyor, and is operable to allow modification of the elevation of a first end of the cross conveyor in relation to the elevation of a second end of the cross conveyor. A processing device is also attached to the cross conveyor near one end of the cross conveyor.
Patent CA-2533671-A1 (CA)
Inventor: BOULAND MEINT JOHANNES
IPC: A46B13/00
Filed: 2004-07-08
Abstract: The present invention relates to a modified extension part (1) and sweeper body (6) for weed mowers, in which the mentioned extension part (1) is constructed as a cylindrical disc provided with through and through recesses (7) and at least two opposite to each other not through and through milled-out recesses (5, 51) to receive in a very inventive way the triangular or polygonal bushes (15) with sweeper body (6) constructed as steel cable (14) , and pressed on the end a preferably triangular bush or cover (15), in which locking is done by means of a spring loaded blocking pin (10) and can be pushed in with the thumb and finger to replace the sweeper body for which a recess (16) comes free and the sweeper body can be replaced, through which in a surprising easy way and without the requirements of tools the sweeper body (6) of the extension part (1) can be replaced.
Patent CA-2536124-A1 (CA)
Title: Heat exchanging apparatus
Inventor: BENOIT DENIS
IPC: F28D20/00
Filed: 2006-02-13
Abstract: A heat exchanging apparatus including a gas fuelled flameless heater and a heat exchanger loop. The heat exchanger loop includes a heat absorbing section which is contained within the flameless heater so that the flameless heater provides a heat source for the heat exchanger loop, and the heat exchanger loop further includes a heat transferring section for transferring heat from the heat exchanger loop to a heat sink.
Patent CA-2540899-A1 (CA)
Inventor: FRENCH DARCIE MARIE
IPC: A41D11/00
Filed: 2006-03-23
Abstract: A crib sheet with attachment points used to attach to the crib rails or bed frame. The crib sheet is used in combination with an infant sleep garment that attaches to the crib sheet by hook and loop mechanism. Attachment to the crib frame or bed frame, rather than the mattress, eliminates the risk that the infant's movements can cause the crib sheet to move or shift.      Two points of attachment lie on either side of the shoulders or upper torso of the infant. The sleep garment has a arm restraint mechanism that acts to prevent movement of the infant's arms so that the infant cannot use its arms to escape the garment or to move itself about the crib or bed.
Patent CA-2541186-A1 (CA)
Title: Cover with drip edge channel
Inventor: BROCHU GUY
IPC: E04D13/064
Filed: 2006-03-23
Abstract: A protective device for use with a gutter to prevent entrance of extraneous matter therein, the gutter having a rear wall, a front wall and a bottom wall which together define an open trough therebetween and wherein the gutter rear wall is designed to be located adjacent to a facia of a building, the protective device having a foraminous planar portion with first and second longitudinally extending sides, the first longitudinally extending side designed to be adjacent the gutter rear wall and having a downwardly extending U-shaped cavity, the cavity being defined by a cavity inner wall and a cavity outer wall, at least one of the cavity walls having apertures therein to permit fluid flow therethrough, and a second longitudinally extending side of the foraminous portion being designed to lie adjacent the gutter front wall.
Patent CA-2542880-A1 (CA)
Title: Pyrimidin-4-yl-3, 4-thione compounds and their use in therapy
Inventor: ZHELEVA DANIELLA I
IPC: C07D417/14
Filed: 2004-10-21
Abstract: The present invention relates to compounds of formula: (I), or pharmaceutically acceptable salts thereof, wherein R1 and R5 are each independently H, C(ORj~) or a hydrocarbyl group optionally substituted by one or more R6 groups; R2, R3, and R4 are each independently H, alkyl or alkenyl, each of which may be optionally substituted with one or more R7 groups; R6 and R7 are each independently halogen, NO2, CN, (CH2)mORa, O(CH2)nORb, (CH2)pNRcRd, CF3, COORe, CONRfRg, CORh, SO3H, SO2Ri, SO2NRjRk, (CH2)qNRa~CORg~, Rf~, (CH2)rNRb~SO2Rh~, SO2NRd~Ri~, SO2NRe'(CH2)s,ORc', heterocycloalkyl or heteroaryl, wherein said heterocycloalkyl and heteroaryl may be optionally substituted by one or more substituents selected from aralkyl, sulfonyl, Rm and CORn; Rg', Rh', Ri' and Rj' are each independently selected from alkyl, aryl, aralkyl and heteroaryl, each of which may be optionally substituted with one or more substituents selected from halogen, OH, NO2, NH2 CF3 and COOH; m, p, q and r are each independently 0, 1, 2 or 3;  n and s are each independently 1, 2, or 3; and Ra-n and Ra'-f' are each independently H or alkyl. Further aspects of the invention relate to pharmaceutical compositions comprising such compounds, and their use in the preparation of a medicament for treating one or more of the following: a proliferative disorder, a viral disorder, a CNS disorder, a stroke, alopecia and diabetes.
Patent CA-2546815-A1 (CA)
Inventor: BOJACK GUIDO
IPC: A01N47/06
Filed: 2004-11-09
Abstract: The invention relates to novel 2-ethyl-4,6-dimethyl-phenyl-substituted spirocyclic tetramic acid derivatives of formula (I), wherein A, B, and G have the meanings indicated above, several methods and intermediate products for the production thereof, the use thereof as pesticides and/or herbicides, and selective herbicides containing 2-ethyl-4,6-dimethyl-phenyl-substituted spirocyclic tetramic acid derivatives of formula (I) (wherein G can also represent hydrogen) and at least one compound which improves tolerance to cultivated plants.
Patent CA-2547057-A1 (CA)
Inventor: OTAKA KEN
IPC: C07D277/32
Filed: 2005-01-13
Abstract: The present invention provides a malononitrile compound represented by the formula (I): wherein any one of X1, X2, X3 and X4 is CR100, wherein R100 is a group represented by the formula: the other three of X1, X2, X3 and X4 each represent nitrogen or CR5, provided that 1 to 3 of X1, X2, X3 and X4 represent nitrogen, and Z represents oxygen, sulfur or NR6, which has pest-controlling activity.
Patent CA-2548691-A1 (CA)
Title: Motionless lens systems and methods
Inventor: TANG YIN S
IPC: G02B3/00
Filed: 2006-05-30
Abstract: Systems and methods are disclosed herein to provide zoom and/or autofocus lenses. For example, in accordance with an embodiment of the present invention, a lens is provided with at least one tunable lens. The focal length and/or focus of the lens may be varied without mechanically moving or changing the separation between one or more lens components.
Patent CA-2551085-A1 (CA)
Title: Ionization modifier for mass spectrometry
Inventor: DOEBELI HEINZ
IPC: G01N33/68
Filed: 2006-06-27
Abstract: The present invention is concerned with a compounds of the general formula (see formula I) wherein R, R', R", R"', R"", X and n are as defined in the description and the claims and the use of said compound as ionization modifier. The invention further relates to a method for the quantification of a polypeptide or fragments thereof from a source containing said polypeptide in labeled and unlabeled form comprising (a) modifying the isolated polypeptide with a ionization modifier, (b) analyzing the prepared polypeptide or fragments thereof by mass spectrometry, and thereby determining the amount of polypeptide or fragments thereof that was present in the source of polypeptide or fragments thereof.
Patent CA-2551924-A1 (CA)
Title: Method for controlling the feed air temperature of a passenger aircraft
Inventor: SCHWAN TORSTEN
IPC: B64D13/00
Filed: 2004-12-30
Abstract: With a method for controlling the temperature of feed air supplied to a cabin area of a passenger aircraft (10), a measurement value for the ambient temperature in the cabin area is determined by means of a temperature sensor system (24). The temperature of the feed air is controlled, dependent upon a deviation of the ambient temperature measurement value in relation to an ambient temperature optimum value. In accordance with the invention, the ambient temperature measurement value is deduced from a number of individual temperature values for different points in the cabin area. In accordance with an example, the temperature sensor system used to establish individual temperature values for a cabin zone includes a number of discreet temperature sensors (24) positioned in this cabin zone, each of which provides an individual temperature value. Preferably, the temperature sensors (24) are distributed evenly over the whole length of the cabin zone in question.
Patent CA-2557427-A1 (CA)
Inventor: TOMASSONI GABE
IPC: B65G25/02
Filed: 2006-08-28
Abstract: A conveyor adapted for use with a refuse collection vehicle is disclosed. The conveyor includes a plurality of elongate slats arranged in side-by-side relation, the plurality of slats being formed by a plurality of slat sets. The upper surfaces of the slats define a convex floor surface for the hold of said vehicle. The conveyor also includes a cross member for and associated with each slat set and attached to each of the slats therein, and a slat drive adapted to reciprocate the slat sets and cross members in a cycling manner. In each cycle, the slat drive simultaneously moves all of the plurality of slats sets and cross members in a first direction, substantially lengthwise with respect to the slats, and then moves the slat sets and cross members in a second direction, opposite the first direction, one cross member and associated slat set at a time.