baber/WOPTO huggingface dataset:
Patent CA-2166897-A1 (CA)
Title: A process for preparing 5-chloro-4-hydroxypyrimidines, 2-chloro enamines as intermediates in this process and their use
Inventor: ZURMUEHLEN FRANK
IPC: C07D239/30
Filed: 1994-07-08
Abstract: A process for preparing 5-chloro-4-hydroxypyrimidines, 2-chloro enamines as intermediates in this process and their use The invention relates to a process for preparing com-pounds of the formula   in which R1 is optionally substituted alkyl, cycloalkyl, aryl or benzyl, in which a chloroacetic ester is convert-ed with ammonia or an ammonium salt into the correspond-ing chloro enamine and the latter is condensed in the presence of a base with formamide. The invention further-more relates to 2-chloro enamines as intermediates in the process.
Patent CA-2169433-A1 (CA)
Title: Adhesion receptor antagonists
Inventor: GANTE JOACHIM
IPC: C07D417/14
Filed: 1996-02-13
Abstract: Compounds of the formula I                I, wherein R1 and Y have the meanings indicated, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses, oncoses, apoplexy, cardiac infarct, inflammations, arteriosclerosis and osteolytic disorders.
Patent CA-2172819-A1 (CA)
Title: Use of Anti-Idiotypic Antibodies to Prevent Hyperacute Rejection of Xenografts
Inventor: KOREN EUGEN
IPC: C07K16/06
Filed: 1994-10-12
Abstract: Antibodies directed against idiotypes on naturally occurring human anti-animal antibodies are disclosed for use in inhibiting xenograft rejection in human patients. An effective quantity of these anti-idiotypic antibodies is injected into the actual or potential xenograft recipient in order to bind to the idiotypes expressed on anti-animal antibodies as well as subpopulations of B lymphocytes, to inhibit hyperacute rejection of transplanted animal tissues or organs by the human patient. Alternatively, anti-idiotypic antibodies are used in the form of immunoaffinity columns to deplete anti-animal antibodies from the recipient's serum. Methods of making mouse monoclonal, mouse recombinant , and human recombinant anti-idiotypic antibodies are described as well as immunoaffinity columns containing immobilized anti-idiotypic antibodies. A method and means for assessing the expected character and severity of a patient's rejection response to transplanted animal tissues is described as well as methods of identification, isolation and suppression of lymphocytes bearing anti-animal idiotypes.
Patent CA-2174825-A1 (CA)
Title: Lubricant composition for use on workpieces in the hot forming of metals
Inventor: PERIARD JACQUES DR
IPC: C10M103/00
Filed: 1996-04-23
Abstract: A  lubricant  composition  suitable  for  use  on workpieces in the hot forming of metals, having surface temperatures ranging from 800°C to 1300°C.
Patent CA-2175877-A1 (CA)
Title: 4-methyl-1-pentene polymer compositions
Inventor: KAN KOJIRO
IPC: C08L23/20
Filed: 1996-05-06
Abstract: A 4-methyl-1-pentene polymer composition is prepared by melt mixing (A) a 4-methyl-1-pentene polymer,  (B) a 1-butene polymer, (C) a propylene polymer, and (D) a triblock copolymer of polystyrene/ethylene-butylene copolymer/ polystyrene and/or a triblock copolymer of polystyrene/ ethylene-propylene copolymer/polystyrene.  The composition has improved gas permeability, flexibility, and mechanical properties and is formed into a film which is heat sealable.
Patent CA-2176100-A1 (CA)
Title: Method of removing a minable product from an underground seam
Inventor: JACKSON DARYL L
IPC: E21B43/29
Filed: 1996-05-08
Abstract: An improved method and equipment of removing a minable product, such as coal, from an underground seam of minable product, such as a coal seam, includes the steps of drilling a vertical hole from the earth's surface through the seam of minable product, installing in the recovery hole an improved recoverable down hole tool, having a vertical auger and a hollow shaft extending from the earth's surface to the auger in the down hole tool, water pumped down the hollow shaft exiting through nozzles mounted from below the auger segments in the down hole tool and spaced vertically along the length of the hollow shaft to the earth's surface through the seam of minable product, the injection holes being drilled in a pattern extending from the recovery hole inserting and sequentially igniting explosives in the injection holes, injecting water sequentially in the injection holes and removing the fractured minable product by operating the down hole tool and water nozzles in the recovery hole and raising said minable product to the earth surface.
Patent CA-2176342-A1 (CA)
Title: Intradermal drug delivery device
Inventor: GROSS JOSEPH
IPC: A61N1/30
Filed: 1994-11-17
Abstract: An intradermal drug delivery device comprises a housing (301a, 301b) having a drug resevoir(312) therewithin and a gas generation chamber (313) separated from the reservoir (312) by a displaceable membrane (311). A microprocessor controlled electrolytic cell (316a 316b, 319) provides gas to expand the gas generation chamber (313) and thereby contract the reservoir (312). A hollow needle (310) communicating at an inner end thereof with the reservoir (312), extends from a lower surface (308) of the housing (301) such that contraction of the reservoir (312)forces drug to escape therefrom via the needle(310). The device permits delivery of drugs of relatively large molecular weights at slow controllable rates. A displaceable protective cover (303) is mounted in means (307) allowing movement of the cover (303) between extended and retracted positions (305, 306). The cover (303) has an adhesive lower surface (309) for attachment to the skin of a subject. In use, a release liner is removed, the device is pressed against the skin and the cover (303) snaps back to the retracted position (306), the needle (310) thereby piercing the skin. After use the housing (301) is pulled away and the cover (303) snaps to the extended position (306) before detaching from the skin, thus concealing the needle (310) befone disposal.
Patent CA-2179274-A1 (CA)
Title: Orthotic seat
Inventor: CARLSON J MARTIN
IPC: A61G5/10
Filed: 1995-10-24
Abstract: A modular orthotic seat (10, 125) is made up of individual shells or modules (12, 125, 14, 16) that are adjustably connected together for accommodating changes in size of the user. The modules (12, 125 14, 16) include a pelvic module (12, 125) for support of the thighs, pelvis and sacrum, a thoracic module (14) for support in the thorax and lumbar regions, and a cervical-head support (16). The modules (12, 125, 14, 16) are mounted on a strut or struts (36) that permit adjustment between the modules (12, 125, 14,16). Suitable bedding or padding (70, 78, 82) can be used for final custom fining. An adjustable seat pan (144) is provided for permitting adjustment of the supporting seat to accommodate angular variations of the pelvic regions of the user.
Patent CA-2180446-A1 (CA)
Title: Pharmaceutical compositions
Inventor: PETTERSEN ERIK OLAI
IPC: A61P35/00
Filed: 1995-01-03
Abstract: Pharmaceutical compositions which are useful for the treatment of cancer or illnesses which arise due to an abnormally elevated cell proliferation comprise acyl derivatives of aromatic aldehydes, especially alylidene diesters and .alpha.-alkoxyarylidene esters of general formula (I).
Patent CA-2184309-A1 (CA)
Inventor: LEHMANN THOMAS
IPC: B01D53/32
Filed: 1996-08-28
Abstract: A process is known for the electrolytic removal of a contaminant from gases, wherein the gas and a liquid electrolyte are passed co- or counter-currently through a fixed bed electrode of an electrolysis cell which has a counterelectrode separated from the fixed bed electrode by a separator and the contaminant is electrochemically converted at an effective cell voltage.  Such cells have hitherto been operated in a flooded state.  According to the invention, the degree of purification may be substantially increased if the fixed bed electrode is operated as a trickle bed reactor.
Patent CA-2184442-A1 (CA)
Title: Process for the preparation of optically active ortho-substituted 4-aryl-dihydropyridines
Inventor: STRAUB ALEXANDER
IPC: A61K31/4427
Filed: 1996-08-29
Abstract: The invention relates to a process for the preparation of optically active ortho-substituted 4-aryl- or heteroaryl-1,4-dihydropyridines by oxidation and subsequent reduction from their opposite enantiomers.
Patent CA-2184772-A1 (CA)
Inventor: CHIH-LIN I
IPC: H04J13/00
Filed: 1996-09-04
Abstract: A code division multiple access system provides a way of allocating an increased data rate to a requesting mobile station. A mobile station requesting a data rate in excess of the basic data rate sends received pilot strength data for its base station and base stations in adjacent cells. The received pilot strength data is used to determine an increased data rate to be assigned to the requesting mobile station. One feature assigns an increased datarate when the received pilot strength data has a predetermined relationship to an established threshold. Another feature utilizes a series of threshold levels, each pair of levels associated with a different permitted data rate. Using the received pilot strength data, a data rate is determined which satisfies all adjacent cellinterference concerns. Another feature uses average adjacent cell capacity loadsrather than threshold levels, together with the received pilot strength data, todetermine the appropriate increased data rate to be assigned to a user requesting an increased data rate.
Patent CA-2186610-A1 (CA)
Inventor: SUMITOMO SAWAJIRI OSAMU
IPC: A44B18/00
Filed: 1995-04-06
Abstract: La présente invention se rapporte à un élément de fixation qui ne génère pas de bruit lorsqu'il vient en contact avec un composant et qu'on y applique une vibration. L'élément de fixation comprend une section base, une section tige implantée et interconnectée à la section base, à une distance prédéterminée de la section base, ainsi qu'une section tête interconnectée à l'extrémité distale de la section base. Au moins une partie de la section tige ou de la section tête comprend (1) un matériau polymère polyphasé possédant une première résine polymère et une seconde résine polymère, ou (2) une résine polymère augmentant le module en flexion de l'élément de fixation. Du fait qu'il ne génère pas de bruit lors d'une vibration, ledit élément de fixation convient particulièrement pour assembler des composants d'automobile.
Patent CA-2187779-A1 (CA)
Title: A method for detecting the presence of a mycobacterium species and a kit and antibodies for use therein
Inventor: VERSCHOOR JAN ADRIANUS
IPC: A61K39/04
Filed: 1995-04-13
Abstract: The invention relates to a diagnostic test for the detection and identification of Mycobacterium species in biological specimens of human and animal origin. The test is based on tile immunological detection of one or more antigens originating from Mycobacterium. To enable tile detection of an antibody-antigen reaction, the antibodies specific for these antigens can be labelled with an enzyme or fluorescent dye or attached to latex particles or any other suitable label. The diagnostic test may be in a form of ELISA and may or may not require concentration of the Mycobacterium antigens prior to the actual test. The invention comprises: the selection and procurement of a suitable mycobacterial species and strain, the isolation and purification of the antigens, preparation of the necessary conjugates for the immunization of tile experimental animals using various carrier molecules, the development of in assay for monitoring the antibody production, caracterization of the antibodies specific for the Mycobacterium antigen/antigens and the development of a diagnostic assay/kit.
Patent CA-2189424-A1 (CA)
Title: Non-steroidal anti-inflammatory ophthalmic suspensions
Inventor: PATEL RAJESH
IPC: A61P29/00
Filed: 1995-05-19
Abstract: Topical ophthalmic formulations of non-steroidal anti-inflammatory agents, particularly diclofenac sodium, include an aqueous mixture of the agent in formulations with a pH and concentration of agent that maintains at least a therapeutic amount in suspension and a therapeutic amount in solution.
Patent CA-2189577-A1 (CA)
Inventor: STEENHAGEN SHAWN K
IPC: G10K11/178
Filed: 1996-11-04
Abstract: An active adaptive control system and method has frequency dependent filtering with a transfer charac-teristic which is a function of a frequency dependent shaped power limitation characteristic maximizing usage of available output transducer authority.  Band separa-tion is provided for different tones.  Power limit parti-tioning is provided for effectively distributing power between correction tones to maximize model performance.
Patent CA-2191584-A1 (CA)
Title: Manufacture of autogenous replacement body parts
Inventor: KHOURI ROGER K
IPC: A61L27/00
Filed: 1995-06-02
Abstract: Disclosed are matrix materials, methods, and devices for manufacture in vivo of autogenous replacement body parts comprising plural distinct tissues. In one embodiment, the replacement body part a a skeletal joint and the new plural distinct tissues include bone and articular cartilage.
Patent CA-2193724-A1 (CA)
Title: Method and apparatus for increasing the flow rate of a liquid through an orifice
Inventor: JAMESON LEE KIRBY
IPC: B29C48/14
Filed: 1995-06-23
Abstract: An apparatus and a method for increasing the flow rate of a pressurized liquid through an orifice by applying ultrasonic energy to a portion of the pressurized liquid. The apparatus (100) includes a die housing (102) which defines a chamber (104) adapted to receive a pressurized liquid and a means for applying ultrasonic energy (116) to a portion of the pressurized liquid. The die housing (102) further includes an inlet (110) adapted to supply the chamber with the pressurized liquid, and an exit orifice (112) defined by the walls of a die tip (136). The exit orifice (112) is adapted to receive the pressurized liquid from the chamber (104) and pass the liquid out of the die housing (102). When the means for applying ultrasonic energy (116) is excited, it applies ultrasonic energy to the pressurized liquid without applying ultrasonic energy to the die tip (136). The method involves supplying a pressurized liquid to the foregoing apparatus (100), applying ultrasonic energy to the pressurized liquid but not the die tip (136) while the exit orifice (112) receives pressurized liquid from the chamber (104), and passing the pressurized liquid out of the exit orifice (112) in the die tip (136).
Patent CA-2194078-A1 (CA)
Title: Switching connector for a radiocommunication terminal and associated jack
Inventor: VILLAIN JEAN-CHRISTOPHE
IPC: H01R13/646
Filed: 1996-12-27
Abstract: his switching connector for a radiocommunication terminal, which can correctly connect the internal circuitry of such a terminal either to an external antenna or to the terminal's own antenna, depending on whether or not a jack for an external antenna is fitted to the connector, essentially comprises, inside the terminal case, an electrical contact (9) that is directly jack-switchable (12) and enables or disables the connection as it is turned on or off.
Patent CA-2195221-A1 (CA)
Inventor: KANAAN ROGER J
IPC: B23B31/22
Filed: 1996-05-24
Abstract: A quick-change chuck (10) has a body (12) having a recess (14) for receipt of a circular tool shank (16) and includes a number of tapered slots (18) communicating with the recess (14). An outer sleeve member (20) is coaxial about the body (12) and axially movable relative thereto. An axial spring (24) is disposed between the sleeve (20) and the body (12) biases the sleeve (20) longitudinally relative to the body (12) to a biased position. The sleeve (20) is axially movable against the biasing force of the spring (24) to a released position. Tapered pins (26) seated within the slots (18) contact a pin engaging surface (22, 122) on the inner diameter of the sleeve (20) and are forced radially inward within the slots (18) so as to extend into the recess (14) in the sleeve's (20) biased position. The pins (18) are movable radially outward within the slots (18) as the sleeve (20) is moved to its released position. The sleeve (20) can include a polymer sleeve (125) surrounding a cylindrical insert (121) with an axially extending slit (135) disposed through the insert (121) and between adjacent pin engaging surfaces (122).
Patent CA-2198998-A1 (CA)
Title: Foamable olefin thermoplastic elastomer compositions and foamed products thereof
Inventor: YAMAOKA HIROYASU
IPC: C08J9/00
Filed: 1997-03-03
Abstract: Disclosed is a foamable olefin thermoplastic elastomer composition comprising (A) a partially crosslinked thermoplastic elastomer composition,  (B) long-chain branch-containing polypropylene and (C) a foaming agent.  The partially crosslinked thermoplastic elastomer composition (A) is obtained by dynamically heat-treating a mixture in the presence of organic peroxide, said mixture comprising specific proportions of a peroxide-crosslinking type olefin copolymer rubber (a), which is an ethylene/.alpha.-olefin copolymer rubber composed of ethylene, an .alpha.-olefin of 3 to 20 carbon atoms and optionally a nonconjugated diene, and a peroxide-decomposition type olefin plastic (b), which is an .alpha.-olefin (co)polymer containing a specific amount of an .alpha.-olefin of 3 to 20 carbon atoms and having a specific MFR.          Also disclosed is a foamed product obtained by heating the foamable olefin thermoplastic elastomer composition.  From the foamable olefin thermoplastic elastomer composition, a foamed product having an expansion ratio of at least 2 times, being free from surface roughening caused by defoaming, being soft to the touch and showing excellent heat resistance and weathering resistance can be produced with high productivity through simplified steps.
Patent CA-2200485-A1 (CA)
Title: Method to estimate the current datapacket rate of a virtual connection, a feedback mechanism using said method and device, switching node and destination node realizing said method
Inventor: MEURISSE WIM POL
IPC: H04L12/56
Filed: 1997-03-19
Abstract: A method is described to estimate the current datapacket rate CCRi, called herein current cell rate, of a connection out of a plurality of connections which are carrying datapackets via a multiplexed transmission channel in a communication network.          The method includes the steps of: - storing in a buffer (B) incoming datapackets of the connections; - determining the total number of datapackets BCTO in the buffer (B); - determining the number of datapackets of the connection BCi in the buffer (B); - measuring an aggregate input datapacket rate CIN of the buffer (B); - estimating the current datapacket rate CCRi via the formulae:                   CCRi=CIN. BCi _____ BCTO
Patent CA-2200492-A1 (CA)
Title: Method and apparatus for collecting fragments of bone tissue
Inventor: LUNDGREN DAN
IPC: A61B17/00
Filed: 1995-09-20
Abstract: The invention relates to method and device for collecting bone tissue fragments at a surgical operation in bone tissue occurring liquid fluid being evacuated by suction from the operation site. In the method liquid is allowed to pass during evacuation by suction into a cylindrical sieve (19) through one open end thereof and through the sieve wall from the inside to the outside thereof. A displaceable end wall (22) disposed at the other end of the sieve is moved axially through the cylindrical sieve in order that bone tissue fragments collected on the inside surface of the sieve will be scraped off therefrom and deposited outside the sieve from said one, open end thereof. The device comprises a cylinder (10) having an inlet and an outlet at one end and the other, respectively, which can be connected into a suction conduit. The cylindrical sieve is located inside the cylinder, a space being provided between the outside curved surface of the sieve and the inside curved surface of the cylinder. One, open end of the sieve communicates with the inlet of the cylinder while the outlet of the cylinder communicates with said space. The end wall disposed at the other end of the sieve can be displaced as a piston axially through the sieve.
Patent CA-2202638-A1 (CA)
Title: System and method for earth probing with deep subsurface penetration using low frequency electromagnetic signals
Inventor: BROWN RUSSELL D
IPC: G01S7/285
Filed: 1994-10-17
Abstract: An earth probing system uses deep penetration of electromagnetic waves into soil and other media. Advantage is taken of lower attenuation of radar waves in soil by frequencies of about three megahertz or less. Bursts of electromagnetic energy of various frequencies in this range are consecutively transmitted. The transmitting antenna (118) is continuously tuned, so as to maintain resonance during each burst, allowing large circulating currents and high power output. In a receiving antenna system, a dual antenna arrangement (111, 112) is providing for obtaining improved reception. A corresponding dual antenna circuit employs "spatial notch filtering", automatic adjustment of antenna gain-frequency variations, as well as compensation for transmitter gain variation. The system may be implemented in a totally analog, totally digital, or hybrid manner. Preferably, a signal processing method detects and digitally samples signals reflected from subsurface layers and buried objects (316, 316'). The invention provides means for removing system distortions and interfering signals, for compensating for aliasing errors and frequency-dependent antenna gain and phase variations, and for avoiding masking errors introduced by strong reflections.
Patent CA-2203068-A1 (CA)
Title: Chromosome 1p gene and gene products related to alzheimer's disease
Inventor: BELOUCHI MAGID
IPC: A61K48/00
Filed: 1997-04-18
Abstract: The present invention discloses nucleic acid molecules encoding genes involved in CNS disorders such as Alzheimer's disease and epilepsy. Also disclosed are gene products, vectors and host cells suitable for expression of such gene products. Methods are providing for detecting the presence of a gene involved in Alzheimer's disease in human subjects and for treating humans suffering from Alzheimer's disease. Furthermore, markers which are associated with Alzheimer's disease are disclosed. Methods in kits for the detection of Alzheimer disease in a subject are additionally provided.
Patent CA-2207950-A1 (CA)
Inventor: STRONG J TODD
IPC: A61C8/00
Filed: 1995-12-15
Abstract: Procédé de mise au point d'un implant (10) pour le squelette consistant à mesurer les caractéristiques physiques de l'os destiné à recevoir l'implant, à produire un macro-modèle de l'implant (10) basé sur ces caractéristiques physiques et à déterminer un micro-modèle de l'implant (10) de façon que la contrainte à l'intérieur de l'os soit maintenue entre 100 et 3000 micro-contraintes pour stimuler la croissance osseuse et minimiser la résorption osseuse pendant qu'une charge fonctionnelle est appliquée. Une partie de base circulaire (30) présente une extrémité de sommet (34), une extrémité apicale opposée (36), et une partie centrale (32) située entre l'extrémité de sommet (34) et l'extrémité apicale (36) et comportant une surface externe (38). Un filetage hélicoïdal (40) s'étend autour d'une partie de la surface externe (38) de la partie centrale (32). La surface du filetage (40) qui se trouve en contact avec l'os augmente à mesure que le filetage (40) se rapproche de l'extrémité de sommet (48), ceci augmentant par conséquent la surface sur laquelle la force est répartie, de l'implant (10) jusque sur l'os qui l'entoure, minimisant la résorption de l'os existant et stimulant la croissance de tissu osseux neuf juste à côté du dispositif (10).