baber/WOPTO huggingface dataset:
Patent EP-1254166-B1 (EP)
Inventor: POHLMEYER KAI
IPC: C07K14/00
Filed: 2001-01-11
Granted: 2008-09-03
Abstract: Recombinant human protein (I), having the biological activity of a histone 1 (H1), or its active fragments, produced in prokaryotic cells, especially Escherichia coli. An independent claim is also included for producing (I). - ACTIVITY : Anticancer; cytostatic; antibiotic; immunomodulatory; endocrinological; antibacterial; antiviral; antifungal; antiparasitic. When tested at 62 Microg/ml against K562 leukemia cells, recombinant histone H1.2 caused 63% cell death after 1 hour, but only 13% death of peripheral blood mononuclear cells. - MECHANISM OF ACTION : Histones are involved in organization of the chromatid structure and in gene repression. They create channels in cell membranes, increasing the permeability and leading to swelling and lysis.
Patent EP-1274582-B1 (EP)
Inventor: SCHASCHEK KARL ERICH ALBERT
IPC: B41C1/10
Filed: 2001-02-22
Granted: 2003-10-22
Abstract: A printing plate is prepared for the insertion of images by applying an ink accepting layer and an ink repelling layer to it. A developing fluid is sprayed onto the ink repelling layer by an ink jet printing group. The developing fluid is sprayed in the image to be printer and the ink repelling layer is etched or dissolved in the sprayed area. The etched or dissolved areas of the ink repelling layer are removed. The method is particularly adapted for use with a waterless printing plate having an ink repelling layer of silicon.
Patent EP-1381433-B1 (EP)
Inventor: MIDDLETON NICHOLAS MARK
IPC: A63B69/36
Filed: 2001-04-20
Granted: 2007-07-11
Abstract: There is disclosed a golf club such as a putter and in one embodiment an attachment for the same. The club head has at least one striking face, a rear face and side faces or edges defining a body of a predetermined thickness to which a shaft is attached. Within the body of the head there is provided a recess in a form which opens into the rear face of the head or as a closed aperture completely defined with the body which is of marginally greater dimensions than, and adapted to receive an object such as a conventionally sized golf ball. The recess or aperture can be disposed substantially centrally of the head behind the striking face of the club head so that the "sweet spot" on the striking face can be substantially centrally disposed of said recess or aperture. Ideal toeheel weight distribution can be achieved in this manner. The club, which is typically a putter, can be used as a practing aid by swinging the same proximate a surface when the article or object is disposed within said recess or aperture. In one embodiment when the putter is swung so that it is no longer proximate the floor, the object or article is released and its momentum causes the same to continue moving in a direction imparted to it by the swinging of the putter. The swing profile of a user can thus be quickly assessed. The attachment embodiment functions in a similar manner.
Patent EP-1255722-B1 (EP)
Inventor: HERZOG REINHARD
IPC: C07C67/327
Filed: 2001-02-16
Granted: 2007-01-17
Abstract: L'invention concerne un procédé pour la production d'un ester d'un acide carboxylique α,β-insaturé par réaction de l'acide carboxylique avec un alcanol C6-C12, un cyclopentanol ou un cyclohexanol en présence d'un catalyseur d'estérification acide et d'un agent d'entraînement servant à supprimer l'eau de réaction formée lors de l'estérification. Le procédé selon l'invention est caractérisé en ce qu'on utilise comme agent d'entraînement l'oléfine constituant la base de l'alcanol.
Patent EP-1280890-B1 (EP)
Inventor: MARLIERE PHILIPPE
IPC: A61K38/00
Filed: 2001-04-27
Granted: 2007-01-03
Abstract: The invention concerns mutant prokaryotic cells, in particular E. coli, capable of producing proteins whereof the amino acid sequences comprise at least a non-conventional amino acid, methods for producing and purifying said proteins and the proteins obtained by said methods. The invention also concerns uses of said cells and proteins in different fields such as in therapy, cosmetics, diagnosis or biosynthesis or biodegradation of organic compounds.
Patent EP-1272033-B1 (EP)
Inventor: KOBER REINER
IPC: A01N25/02
Filed: 2001-03-12
Granted: 2004-06-09
Abstract: The present invention relates to an agrotechnical formulation which comprises, in each case based on the total weight of the formulation:a) 20 to 99.9% by weight of at least one cyclohexanepolycarboxylic ester of the formula Iin whichR<1 >is C1-C10-alkyl or C3-C8-cycloalkyl;m is 0, 1, 2 or 3; andn is 2, 3 or 4; andR is H or C1-C30-alkyl, where at least one radical R is C1-C30-alkyl;b) 0 to 70% by weight of water;c) 0.1 to 60% by weight of at least one adjuvant and/or additive; andd) 0 to 70% by weight of at least one active ingredient for plant treatment.
Patent EP-1287003-B1 (EP)
Inventor: HANDA VIJAY KUMAR
IPC: A61P31/04
Filed: 2001-05-16
Granted: 2004-08-04
Abstract: There is described a process for the preparation of a pure amorphous form of cefuroxime axetil which involves dissolving crystalline cefuroxime axetil in acetic acid including at least 5% v/v water and recovering said amorphous form of cefuroxime axetil from the solution by the addition of additional water, the solution being added all at once to the additional water being present in a volume which is sufficient to precipitate said amorphous cefuroxime axetil.
Patent EP-1282397-B1 (EP)
Inventor: CATROUX PHILIPPE
IPC: A61K8/49
Filed: 2001-05-14
Granted: 2005-05-04
Abstract: The invention concerns the use for topical application of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent and a cosmetic treatment method to obtain protection of the organism against pollution effects.
Patent EP-1295968-B1 (EP)
Inventor: FURUYA NAGAKAZU
IPC: H01M4/04
Filed: 2001-06-04
Granted: 2008-04-30
Abstract: A method for manufacturing a gas diffusion electrode for use as an oxygen cathode in a chlor-alkari electrolytic and in a fuel cell in a short time through a simple operation, a gas diffusion electrode, and a fuel cell employing the gas diffusion electrode as a compositional material. A gas diffusion electrode material principally comprising micro particles of fluororesin dispersed in dispersion medium is deposited, by electrophoresis, on the surface of a conductive base material to form a porous deposit containing fluororesin serving as the gas supply layer and/or the reaction layer of the gas diffusion electrode. <IMAGE>
Patent EP-1306429-B1 (EP)
Inventor: NODA MASAHARU
IPC: G01N33/50
Filed: 2001-07-23
Granted: 2011-05-04
Abstract: L'invention porte sur un procédé de promotion de l'activité de promoteurs ou d'inhibiteurs du PTPκ, remède utile contre les troubles du système nerveux central dus à la monoamine et les ulcères gastriques causés par l∫i⊃'Helicobacter pilori∫/i⊃ ou la pléiotrophine, en utilisant les fonctions physiologiques du PTPκ; et sur un animal modèle peu sensible aux excitants, aux toxines du ∫i⊃pilori∫/i⊃ ou à la pléiotrophine. Le criblage de l'activité des promoteurs ou des inhibiteurs du PTPκ s'effectue par administration d'une substance d'essai de PTPκ à une souris à gène manquant et à une souris de type sauvage, puis par comparaison et évaluation de l'action du PTPκ sur ces animaux (par exemple la survenance de troubles du système nerveux central dus à la monoamine, les possibilités d'adaptation à un nouvel environnement, la réponse au stress, les possibilités de fixation de la toxine du ∫i⊃pilori∫/i⊃ ou de la pléiotrophine).
Patent EP-1401438-B1 (EP)
Inventor: TAS SINAN
IPC: A61K8/14
Filed: 2001-07-02
Granted: 2005-09-28
Abstract: The invention relates to a medicament for treatment of a patient having a tumor wherein Hedgehog/Smoothened signaling is utilized for prevention of apoptosis of tumor cells, comprising cyclopamine or another molecule that selectively inhibits Hedgehog/Smoothened signaling, wherein cyclopamine or said another molecule is in an amount adequate for a dosing that induces apoptosis of the tumor cells in the patient and causes decrease of size or disappearance of the tumor.
Patent EP-1313792-B1 (EP)
Inventor: THETFORD DEAN
IPC: C09D7/45
Filed: 2001-08-03
Granted: 2005-12-14
Abstract: A dispersion comprising a particulate solid, a polar organic liquid and a dispersant of formula (1) wherein R is optionally substituted C<SUB>4-50</SUB>-hydrocarbyl; X is -O-, -S- or -NR<SUP>2</SUP>-; R<SUP>1 </SUP>is hydrogen or C<SUB>1-6</SUB>, -alkyl which may be linear or branched; R<SUP>2 </SUP>is hydrogen or C<SUB>1-6</SUB>, alkyl which may be linear or branched or a group -(C<SUB>2</SUB>H<SUB>4</SUB>O)<SUB>n</SUB>(AO)<SUB>p</SUB>-R<SUP>1</SUP>; AO is alkyleneoxy containing 3 or more carbon atoms; n is 0 to 30; p is 4 to 100; and p>n; and a is from 1 to 3. Preferred compounds are where R<SUP>1 </SUP>is hydrogen, X is -O- and a is 1 and R is the residue of 2-naphthol.
Patent EP-1299657-B1 (EP)
Inventor: KURZ GERHARD
IPC: F16D69/00
Filed: 2001-06-21
Granted: 2008-04-09
Abstract: In a brake shoe ( 1 ) comprising a carrier plate ( 2 ) having arranged thereon first a dampening and noise-reducing intermediate layer ( 4 ) and then a friction lining ( 6 ), it is provided that the intermediate layer ( 4 ), on the side thereof facing towards the friction lining ( 6 ), comprises a three-dimensional surface structure, and that the friction lining ( 6 ) on the carrier-plate side is adapted to the surface contour ( 5 ) of the intermediate layer ( 4 ).
Patent EP-1299253-B1 (EP)
Inventor: HERBELLEAU YVES
IPC: B60C15/06
Filed: 2001-06-25
Granted: 2010-05-19
Abstract: A tire comprising a crown, two sidewalls and two beads, a carcass reinforcement anchored in each of the beads and a crown reinforcement. The carcass reinforcement comprises at least two circumferential alignments of first reinforcing threads of high elasticity modulus, each circumferential alignment of the first reinforcing threads being, within each bead, bordered axially by second reinforcing threads oriented substantially circumferentially. The first reinforcing threads and the second reinforcing threads are separated by a layer of mix of very high elasticity modulus. The second reinforcements are arranged in a spiral and formed of monofilaments or unit threads of steel.
Patent EP-1322508-B1 (EP)
Inventor: SZABO GERGELY
IPC: B60T8/1755
Filed: 2001-09-13
Granted: 2008-05-07
Abstract: The invention relates to a method for redundantly estimating, i.e. by various sub-methods, the risk of lateral overturn of a vehicle. One sub-method involves estimating the risk of overturn according to the actual braking state of the vehicle-braking or strong braking, or not braking or slight braking-by monitoring the rotational speed behavior of the wheels on the inside of the turn. Another sub-method involves pre-calculating the rolling motion of the vehicle about the longitudinal axis thereof over a short time span of, for example, 0.5 s to 1.5 s on the basis of instantaneous movement parameters and assessing the risk of overturn on the basis of the anticipated rolling motion.
Patent EP-1435189-B1 (EP)
Inventor: DE LUCA ENRICO
IPC: H04W64/00
Filed: 2001-10-12
Granted: 2009-02-11
Abstract: In a system for providing location information for mobile users subscribing to a network of an operator and roaming in a different networks not supporting the same LoCation Services positioning feature as in the subscriber network, any kind of node and/or application accessing through a gateway the subscriber's network is provided with subscriber's location information based on the address - in terms of denomination of the geographical area pertaining to said different network - of the mobile switching center or the Visitor Location Register or the Serving GPRS Support Node.
Patent EP-1334564-B1 (EP)
Inventor: THURSTON ANDY
IPC: H04L7/08
Filed: 2001-11-01
Granted: 2005-04-27
Abstract: The invention provides a receiver that is capable of deducing the timing of a received signal having a frame structure and corresponding methods. Each frame contains a synchronization word. The receiver correlates the known synchronization word against the received signal to determine the position of the synchronization word. The correlation results can be accumulated over several frames' worth of the signal in order to enhance the determination. The frame boundaries within the signal can be translated and the process of determining the synchronization word position can then be repeated. In this manner, several results for the synchronization word position can be obtained and the best selected. A thresholding process can be used to curtail the number of frames' worth of the received signal that needs to be processed and a mechanism is provided to prevent the thresholding process from biasing the determination of the synchronization word position.
Patent EP-1327368-B1 (EP)
Title: Method and wireless terminal for acquiring service using stored tdma digital control channel information
Inventor: REFAI WAIL M
IPC: H04M1/27
Filed: 2001-10-11
Granted: 2006-08-09
Abstract: Methods for acquiring service for a wireless terminal can include the steps of camping on a control channel and receiving a request for an operation to be performed by the wireless terminal that is performed by the wireless terminal mutually exclusive of camping on the control channel. Control channel information associated with the control channel on which the wireless terminal was camped is stored and the requested operation is performed. The stored control channel information is used to acquire service for the wireless terminal. Related wireless terminals and systems are disclosed.
Patent EP-1352040-B1 (EP)
Inventor: VAN BEIJNUM JOHANNES
IPC: C10G65/12
Filed: 2001-12-18
Granted: 2005-08-17
Abstract: A process to prepare a spindle oil, light machine oil and a medium machine oil base oil grade by: (a) performing a separate catalytic dewaxing on a spindle oil fraction, a light machine oil fraction and a medium machine oil fraction as obtained in a vacuum distillation of a bottoms fraction of a fuels hydrocracking process; (b) performing a separate hydrofinishing of the light and medium machine oil fractions obtained in step (a); (c) separating the low boiling compounds from the spindle oil, light machine oil and medium machine oil fractions as obtained in step (a) and (b) and obtaining the spindle oil, light machine oil and medium machine oil base oil grade; (d) wherein the vacuum distillation is performed by altematingly performing the distillation in two modes wherein the first mode (d 1 ) the bottoms fraction is separated into a gas oil fraction, a spindle oil fraction, a medium machine oil fraction and a first rest fraction boiling between said spindle oil and medium machine oil fraction and in the second mode (d 2 ) the bottoms fraction is separated into a gas oil fraction, a spindle oil fraction, a light machine oil fraction and a second rest fraction boiling above the light machine oil fraction.
Patent EP-1368666-B1 (EP)
Inventor: FELDMAN STEVEN
IPC: G01R1/073
Filed: 2001-12-11
Granted: 2005-03-16
Abstract: A spring probe block assembly includes an insulative housing. A probe connector having a signal probe, an insulative layer, and a conductive shell is positioned within the housing. At least one ground probe is also positioned within the housing. The ground probe and the conductive shell of the probe connector are electrically connected by a grounding element. The grounding element is configured to elastically deform the ground probe in such a manner as to create spring energy in the ground probe. The spring energy generates a normal force between the ground probe and the grounding element which maintains the ground probe in its position. Also, a method for retaining a spring probe in a housing by elastically deforming the spring probe to maintain a spring force between the spring probe and the housing.
Patent EP-1289076-B1 (EP)
Inventor: DUQUERROY PATRICK M
IPC: H01R13/646
Filed: 2002-07-22
Granted: 2005-06-15
Abstract: A coaxial connector (1, 30) for connecting a first contacting means (4) and a second contacting means (15). The coaxial connector (1, 30) having a dielectric housing (6, 42) an inner conductor (8, 31) electrically connected to the first contacting means (4) and resiliently biased between a mated position and an unmated position. An outer conductor positioned adjacent to the dielectric (6, 42) having a first outer conductor section (8, 31) and a second outer conductor section (9, 32) resiliently biased in respect to the first outer conductor section (8, 31) between a mated position and an unmated position. The second contacting means (15) having a first contact pad (60) that contacts the second outer conductor section (9, 32) and a second contact pad (61) that contacts the inner conductor (3, 46) when the second outer conductor section (9, 32) and the inner conductor (3, 46) are in the mated position. <IMAGE>
Patent EP-1308689-B1 (EP)
Inventor: KEIICHI KUNIMOTO
IPC: A63F13/219
Filed: 2002-11-06
Granted: 2007-08-01
Abstract: An optical device controller in the type of imitative gun, which comprises a trigger-like portion (9), a barrel-like portion (1) having a muzzle-like opening (1a), a gas passage forming portion (6) fixed in connection with a rear end of the barrel-like portion (1) for providing a gas passage (5) formed therein, a grip portion (7) in which a gas chamber (34) and a gas leading passage (35) for leading a gas from the gas chamber (34) to the gas passage (5) formed in the gas passage forming portion (6) are provided, an optical device (50) positioned in the barrel-like portion (1) to face the outside through the muzzle-like opening (1a), an operation controlling portion (55) for sifting the optical device (50) from an inoperative condition to an operating condition in response to movement of the trigger-like portion (9), a movable valve (36) provided on the gas leading passage (35) for controlling the gas leading passage (35) to be open in response to the movement of the trigger-like portion (9), and a sliding member (4) having a pressure receiving portion (4d) formed therein to be positioned at the back of the barrel-like portion (1) for receiving pressure of the gas coming through the gas passage (5) formed in the gas passage forming portion (6) and the gas leading passage (35) which is controlled to be open by the movable valve (35) and provided to be moved back along the barrel-like portion (1) with the pressure of the gas acting on the pressure receiving portion (4d). <IMAGE>
Patent EP-1296142-B1 (EP)
Inventor: NEMETH EDWARD F
IPC: A61K31/715
Filed: 1992-08-21
Granted: 2005-12-07
Abstract: Method and composition useful for treating a patient having a disease characterized by an abnormal level of one or more components, the activity of which is regulated or affected by activity of one or more Ca<sup>2+</sup> receptors. Novel compounds useful in these methods and compositions are also provided. The method includes administering to the patient a therapeutically effective amount of a molecule active at one or more Ca<sup>2+</sup> receptors as an agonist or antagonist. Preferably, the molecule is able to act as either a selective agonist or antagonist at a Ca<sup>2+</sup> receptor of one or more but not all cells chosen from the group consisting of parathyroid cells, bone osteoclasts, juxtaglomerular kidney cells, proximal tubule kidney cells, keratinocytes, parafollicular thyroid cells and placental throphoblasts and a pharmaceutically acceptable carrier.
Patent EP-1319584-B1 (EP)
IPC: B62D33/02
Filed: 2002-12-13
Granted: 2005-12-21
Abstract: The tipping body (2) consists of a body assembled from at least three longitudinal module components and with a U-shaped or semi-circular cross section. The body comprises two panel-form laterally reversed side modules (12) forming a side wall module pair, and a base module (18) forming the third module. The base module in the region of its upper longitudinal edges is connected to the lower longitudinal edges of the side wall modules by cold joining points (22).
Patent EP-1260141-B1 (EP)
Inventor: VAN OCHTEN SANDER ANTONIE
IPC: A22B5/00
Filed: 2000-01-24
Granted: 2012-01-04
Abstract: The invention relates to a vent cutter (11,29) for separating a bung (36) and a carcass (3), comprising a jacket-like knife (30) and engaging means for engaging an anus (34) by insertion of a central core (32) into the anus, which engaging means after drilling out the anus are at least partly enveloped by the jacket-like knife, characterised in that, the core is displaceable in axial direction relative to the jacket-like knife, such that prior to drilling the core can be inserted into the anus, and after drilling out the core is at least partly enveloped by the jacket-like knife, whereby the anus is enclosed between the jacket-like knife and the outer end (33) of the core.
Patent EP-1266629-B1 (EP)
Inventor: DOMINGUEZ LARRY
IPC: A61B17/12
Filed: 2002-05-30
Granted: 2006-11-29
Abstract: A balloon catheter comprises a catheter body (10) which has a proximal (14) end and a distal (16) end and which defines an inflation lumen (24), and a delivery lumen (26) separate from the inflation lumen. A balloon (22) is provided adjacent the distal end (16), and an inflation port (18) is provided at the proximal end (14), which communicates via the inflation lumen (24) with the balloon (22). A delivery port (20) is provided at the proximal end (14) which communicates with a guidewire opening (30) at the distal (16). A side opening (28) adjacent the distal end (16), spaced from the guidewire opening (30), communicates with the delivery lumen (26). The balloon (22) is substantially radially aligned with said side opening (28) and substantially oppositely positioned on the catheter (10) with respect to the side opening (28). The catheter (10) can be used to place a medical agent at a desired location within a patient's vessel (64), for example to place an embolic coil (46) is placed at a location with an aneurysm (60). <IMAGE>   <IMAGE>
Patent EP-1359683-B1 (EP)
Inventor: BULJORE SOODESH
IPC: H04B7/04
Filed: 2002-04-30
Granted: 2006-08-30
Abstract: A method of closed-loop multi-stream wireless communication between a transmitter (1) comprising a transmit antenna array of N transmit antenna elements and a receiver (3) comprising a receive antenna array (4) of M receive antenna elements, wherein a plurality of distinct data streams (x1, x2) are transmitted from the transmit antenna array to the receive antenna array and the data streams are weighted by respective complex weighting matrices before being applied to the transmit antenna array. The distinct data streams are separated and estimated at the receiver. The distinct data streams (x1, x2) are applied to respective sub-groups (6, 7) of the transmit antenna elements at least one of which comprises a plurality of the transmit antenna elements, each of the sub-groups comprising at least Nd transmit antenna elements, where M is greater than or equal to (N/Nd). The complex weighting matrices (v1 to vn) are functions of the respective transmission channels (hij) of the data streams (x1, to xG) including the respective sub-groups of transmit antenna elements. <??>Nd is preferably greater than or equal to two. Each of the complex weighting matrices is calculated to be substantially equal to the eigenvector corresponding to the largest eigenvalue of the matrix H<H>H, where H is the matrix of the equivalent channel including the respective sub-groups of transmit antenna elements (6, 7) seen by the corresponding data stream and H<H> is the Hermitian transform of the matrix H. The number of the transmit antenna elements in each of the sub-groups is preferably re-configurable during operation as a function of channel conditions. <IMAGE>