baber/WOPTO huggingface dataset:
Patent MA-39947-A (MA)
Title: Dérivés aminoestérifiés
Inventor: AMARI GABRIELE
IPC: C07D409/14
Filed: 2015-06-03
Abstract: L'invention concerne de nouveaux composés qui sont à la fois des inhibiteurs de l'enzyme phosphodiestérase 4 (pde4) et des antagonistes du récepteur muscarinique m3, des procédés de préparation de tels composés, des compositions les contenant et leur utilisation thérapeutique. Dosage de binging m3: des cellules de clones cho-ki exprimant le récepteur m3 humain (swissprot p20309) ont été récoltées dans une solution saline tamponnée au phosphate sans ca ++ / mg ++ et recueillies par centrifugation à 1500 tr / min pendant 3 min. Les pastilles ont été remises en suspension dans du tampon a glacé (tris-hcl 15 mm ph 7,4, mgcl2 2 mm, edta 0,3 mm, egta 1 mm) et homogénéisées par un politron pbi (réglage 5 pendant 15 s). La fraction membranaire brute a été recueillie par deux étapes de centrifugation consécutives à 40000 g pendant 20 min à 4 ° c, séparées par une étape de lavage dans le tampon a. Les pastilles obtenues ont finalement été remises en suspension dans du tampon b (tris hcl 75 mm, ph 7,4, 12,5 mm). Mgcl2, edta 0,3 mm, egta 1 mm, saccharose 250 mm) et des aliquotes ont été stockés à - 80 ° c. Le jour de l'expérience, les membranes congelées ont été remises en suspension dans du tampon c (tris-hcl 50 mm, ph 7,4, mgcb 2,5 mm, edta 1 mm). Le ligand radioélectrique muscarinique non sélectif [3h] -n-méthyl scopolamine (mol. Pharmacol.45: 899-907) a été utilisé pour marquer les sites de liaison à m3. Les expériences de liaison ont été effectuées en double (courbes de concentration en dix points) dans des plaques à 96 puits à une concentration de radioligand de 0,1-0,3 nm. La liaison non spécifique a été déterminée en présence de n-méthyl scopolamine à froid 10 um. Les échantillons (volume final 0,75 ml) ont été incubés à la température ambiante pendant 90 minutes. La réaction a été arrêtée par filtration rapide à travers des plaques unifilter gf / b et deux lavages (0,75 ml) avec du tampon froid c en utilisant un harvester filtermate harvester. La radioactivité sur les filtres a été mesurée par un compteur à scintillation de microplaques tricarb 2500 (perkinelmer). Des composés représentatifs de l'invention, lorsqu'ils ont été testés dans l'un des protocoles mentionnés ci-dessus, ont présenté une ic50 inférieure à 100 nm. Des composés représentatifs de l'invention présentaient une ic50 inférieure à 100 nm à la fois dans les dosages sans cellules pde4 et dans les taux de liaison à m3.
Patent OA-08955-A (OA)
Title: Oximino ether compounds
IPC: C07C49/757
Filed: 1988-09-27
Abstract: The invention provides compounds of the general formula <CHEM> wherein R represents a hydrogen atom, or an optionally substituted alkyl or acyl group, or an alkenyl or alkynyl group or an inorganic or organic cation; R<1> represents an alkyl, haloalkyl, alkenyl, alkynyl or optionally substituted aralkyl or phenyl group; R<2> represents an optionally substituted alkyl or phenalkyl group or a cycloalkyl, alkenyl, haloalkenyl or alkynyl group;  each R<3> represents an optionally substituted alkyl group; one of R<4> or R<5> represents a hydrogen atom or an alkyl group while the other of R<4> and R<5> represents an optionally substituted phenyl group; together with their use as herbicides and their preparation using novel intermediates.
Patent PH-18933-A (PH)
Title: Triazole antifungal agents
Inventor: RICHARDSON KENNETH
IPC: A01N43/653
Filed: 1984-01-30
Abstract: Triazoles of the formula: 
<CHEM>
 and their pharmaceutically and agriculturally acceptable salts, wherein m is 0, 1, 2, 3 or 4 and n is 0, 1, 2, 3 or 4. The compounds are human and agricultural fungicides.
Patent PH-21594-A (PH)
Title: Improved antiinflammatory salts of piroxicam
Inventor: GEORGE LOMBARDINO JOSEPH
IPC: C07D417/12
Filed: 1985-10-10
Abstract: Improved antiinflammatory salts of piroxicam consist of a 1 : 1 salt of piroxicam with antidepressant doxepin, with bronchodilator pirbuterol or isoproterenol, with H<sub>2</sub>-antagonist inhibitor 2-guanidino-4-(2-methyl-4-imidazolyl)thiazole, with pyridoxine, a member of the vitamin B<sub>6</sub> complex, or with anti- hypertensive trimazosin.
Patent PH-25317-A (PH)
Title: FUSED THIENO-, PYRAZOLO- or FURANS-TETRAHYDROAMINO-QUINOLINOLS, AMINOTETRAHYDROBENZONAPHTHYRIDINES, THEIR USE AS MEDICAMENTS
Inventor: SHUTSKE GREGORY MICHAEL
IPC: C07D495/04
Filed: 1987-11-23
Abstract: There are disclosed compounds of the formula <CHEM>  where =X-Y- is = @@S-, =N-@@, =CH-N=CH- or = @@O-,      R4 being loweralkyl and R5 being hydrogen or loweralkyl,   -Z- is - @- or -@@- , n is 1, 2 or 3, R1 and R2 are each independently hydrogen, loweralkyl or arylloweralkyl, and R3 is hydrogen or loweralkyl, with the proviso that when =X-Y-is =N- @@ ,      n is 2 or 3, R1 is hydrogen and R2 is hydrogen or loweralkyl,   Z is not - @-, which compounds are useful for enhancing memory and for treating Alzheimer's disease.
Patent PH-25001-A (PH)
Title: Unitary superconducting electromagnet
Inventor: HUSON FREDERICK R
IPC: G01R33/38
Filed: 1988-08-12
Abstract: A unitary superconducting electromagnet (10) especially adapted for use in medical or test apparatus with nuclear magnetic resonance (NMR) and spectroscopy at intensities above the magnetic saturation of iron so high as around ten (10) Tesla. The electromagnet (10) includes an inner generally cylindrical body (12) having a central bore (14) and an outer magnetic iron body (16) positioned concentrically about the inner body (12). One embodiment of the electromagnet (10) has adjusting blocks (110) secured to the inner body (12) for movement of the inner body (12) radially and longitudinally of the outer body (16) for precise positioning. Another embodiment shown in FIGS. 16-18 illustrates a small bore electromagnet (10A) having the inner body (12A) fixed relative to outer magnetic iron body (16A) with the outer body (16A) being exposed to the cooling fluid.
Patent UY-32540-A (UY)
Title: Composiciones que incluyen compuestos que contienen la {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del ácido propano-1-sulfónico y métodos para fabricar estas composiciones
Inventor: IBRAHIM PRABHA N
IPC: A61K9/10
Filed: 2010-04-05
Abstract: Se proporcionan dispersiones sólidas, complejos moleculares sólidos, sales y polimorfos cristalinos que contienen la {3-[5-(4-cloro-fenil)-1H-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del ácido propano-1-sulfónico.
Patent UY-32688-A (UY)
Title: 17B(BETA)-ALQUIL-17a(ALFA)-OXI-ESTRATRIENOS
Inventor: GERISCH DR MICHAEL
IPC: A61K31/56
Filed: 2010-06-03
Abstract: 17b(beta)-alquil-17a(alfa)-oxi-estratrienos de fórmula (I), procesos para prepararlos, el uso de los 17b(beta)-alquil-17a(alfa)-oxi-estratrienos para preparar fármacos y preparaciones farmacéuticas que comprenden estos compuestos.
Patent UY-35411-A (UY)
Title: Dispositivo para inhalación, método y de control y programa de computación
Inventor: ANAND GUMASTE
IPC: A61M15/00
Filed: 2014-03-13
Abstract: La invención proporciona un dispositivo para inhalación que usa un elemento vibratorio impulsado eléctricamente para liberar una dosis de un fármaco en un canal de flujo y un controlador para ctivar/desactivar el elemento vibratorio. Una disposición de sensor puede diferenciar entre el flujo de inhalación y el flujo de exhalación a través del canal de flujo, para contribuir a formar un modelo del patrón de respiración del usuario. El dispositivo puede detectar en forma confiable patrones de flujo de inhalación de pacientes de todas las edades.
Patent UY-39211-A (UY)
Title: Agente estabilizador de suspensión
Inventor: MATHEUS ANTUNES GUIMARÃES
IPC: D21B1/00
Filed: 2021-05-11
Abstract: La presente invención se refiere al uso de una celulosa microfibrilada como agente estabilizador de suspensión, agente estructurante de red o aditivo estructurante de red en la fabricación de una composición líquida que tiene un sistema particulado. Preferiblemente, la celulosa microfibrilada está presente entre el 0,5% y el 5,0% en peso. en una composición líquida estabilizada. La composición líquida estabilizada también tiene un sistema de partículas, que tiene una pluralidad de partículas, una pluralidad de cápsulas o mezclas de las mismas.
Patent YU-17697-A (YU)
Inventor: BRANKO JEREMIC
Filed: 1997-05-08
Abstract: Pronalazak se, prema osnovnoj varijanti izvodjenja, odnosi na mehanizam za zatezanje i sprečavanje proklizavanja gumene navlake oko pneumatika koji je izveden od većeg broja sajli (60) koje su vulkanizirane u protektoru (1) navlake. Petlje (61, 62) sajli (60) štrče izvan protektora (1) duž bočnica (14) pneumatika (13). Na prednjoj strani pneumatika (13) petlje (61) provučene su kroz proreze (64) na pločicama (63) koje naležu na bočnicu (14). Za petlje (61) zakačene su opruge (65) koje drugim krajem obuhvataju prsten (66) provučen kroz otvore (67) na čaurama (68). Čaure (68) navučene su na vijke (69) koji spajaju naplatak (N) sa dobošem (D) točka.
Patent YU-72783-A (YU)
Title: Improvement in the process of obtining melamine
Inventor: HARDEVELD R VAN
IPC: C07D251/10
Filed: 1983-03-28
Abstract: An improved process for the preparation of melamine from urea or thermal decomposition products thereof. A melamine containing reaction mixture is cooled with an aqueous medium to form an aqueous product stream containing melamine and reaction by-products. Product melamine is separated from the aqueous product stream leaving a residual aqueous stream which is recycled into the process. A portion of this residual aqueous stream still containing reaction by-product is treated to remove by-products therefrom prior to being recycled to the process.
Patent AT-A164195-A (AT)
Inventor: URBANEK OTTO DIPL ING DR
IPC: B29C48/58
Filed: 1995-10-04
Abstract: PCT No. PCT/AT96/00182 Sec. 371 Date May 30, 1997 Sec. 102(e) Date May 30, 1997 PCT Filed Oct. 3, 1996 PCT Pub. No. WO97/13001 PCT Pub. Date Apr. 10, 1997A process for producing a coating on the surface of a plastifier screw for injection molding machines includes applying to a hard-metallic or ceramic substrate with low distortion, a steel screw base element, by high-speed flame spraying. During the coating process, a spray jet treats the different surface regions of the screw base element including the flanks and top of a rib as well as the base of the screw, independently.
Patent AT-A333679-A (AT)
IPC: A61N1/32
Filed: 1979-05-03
Abstract: 1. A massage apparatus having massage rollers (8, 9) and a current generator which consists of a permanent magnet (1) and [with]* a rotor (18) provided with windings (16, 17) and whose drive is derived by means of a drive pinion (13) and a drive shaft (14) from the angular movement of one (9) of the massage rollers (8, 9), which is mounted in an insulated manner and is conductively connected to the antipoles (22, 23) of the windings (16, 17) of the current generator by way of the pinion (13) and the drive shaft (14), while the earth poles (19, 20) of the said windings (16, 17) are connected by way of a slip ring (21) mounted in an insulated manner on the drive shaft (14) and a first part (25') of a current collector (25) to earth, to which the other massage roller (8) is connected, and in order to generate timed short-circuit pulses during the rotation of the drive shaft (14) a second part (25") of the current collector (25) conductively connected to the first part co-operates periodically with a contact member (26) mounted on the drive shaft (14) and connected thereto, characterised in that the drive shaft (14) having a core of conducting material is surrounded in given areas by a sleeve (24) which consists of insulating material and which carries both the rotor (18) and the slip ring (21), and a pin (26) consisting of conducting material and acting as a contact member co-operating periodically with the second part (25") of the current collector (25) passes through the said sleeve (24) and the drive shaft (14).
Patent BE-822077-A (BE)
Title: Double wedge control for rolling mill stand - giving wider range of roll gap settings
Inventor: POLYAKOV M G
IPC: B21B13/10
Filed: 1974-11-12
Abstract: Rolling mill stand comprises a framework in which are mounted bearing blocks, with the rolls and mechanisms for the control of the roll spacing each comprising a wedge placed between the frame and the blocks, and a threaded screw nut unit the single start threaded female of which is fixed into a fixed part of the frame and the control screw is joined to the wedge, so that, when the screw turns, the roll joined to the wedge by means of the blocks, moves in the radial direction, controlling the spacing. The mechanism specif. has a supplementary double wedge joined to the slope of the main wedge and a two-start female thread of the same hand and the first, one-start female thread cooperates with a two start screw joined to the supplementary wedge so that rotation of the screw produces a displacement of the principal and supplementary wedges in opposite directions, so that the rolls can be displaced radially further by turning the second screw. The rolling mill stand can be used for a much wider range of thickness settings using the double wedge arrangement.
Patent BE-892890-A (BE)
Title: Large ceramic porous prod. and fuel gas prodn. - using combustible solids in raw ceramic mix, drying and firing with water injection
IPC: C04B38/06
Filed: 1982-04-16
Abstract: Method of obtaining simultaneously large ceramic products e.g. bricks, and combustible gas, in an appts. which is isolated and sealed so as to be gas tight, and which is heated indirectly, is described. The raw ceramic pieces are prepd. from a clay contg. 10-60% combustibles such as coal and are dried to 2-3% moisture at up to 200 deg.C., then heat treated at up to 900 deg.C. max. to effect hydrothermal solidification of the clay and degassing and gasification of the combustible elements. The hydrothermal solidification of the ceramic and the gasification of the combustibles are effected by injection of a gasification agent, pref. water at 700-900 deg.C, followed by cooling of the products, the steam and the gas being evacuated from the appts. by means of a gas duct, until the start of cooling, such that a predetermined overpressure of at least 100 Pa exists in the appts. The fuel gas is led as hot gas directly to the appts. by means of gas ducts, to fuel the indirect heating, and to other gas burning appts. for mfr. fired ceramic prods. often cooling to 150-500 deg.C deg.C. The appts. is used for prodn. of light, heat insulating materials. Two processes are combined, saving costs.
Patent BE-897591-A (BE)
Title: Fond de chambre de combustion pour chaudiere a couche fourbillonnante
IPC: F23C10/20
Filed: 1983-08-24
Abstract: Le fond (1) comprend une plaque de fond constitutée par des tubes (2) transportant un fluide de refroidissement et reliés les uns aux autres par des entretoises (4) présentant des orifices de passage d'air (5) surmontés par des toles (6) soudées aux tubles (2). Sur le coté intérieur du fond, il y a une boite a eau (33) qui est bubdivisée par des parois (9) en chambres à air (8).
Patent BE-897942-A (BE)
Title: Anchoring hook for tying masonry to concrete works - includes bent end housed in groove in concrete to give firm connection
IPC: E04B1/41
Filed: 1983-10-06
Abstract: The twisted or deformed round steel ties are bent to a particular pattern and are enforced in a groove in the concrete work. A 90 deg. rotation blocks the tie in the groove and the tie can be submitted to tension. The groove large section allows deep mortar penetration into the groove creating a solid reinforced joint.(0/1)
Patent BE-898719-A (BE)
Title: Systeme d'alimentation a deux carburants pour moteurs a conbustion interne
Inventor: BILLINGSLEY H C
IPC: F02M1/16
Filed: 1984-01-20
Abstract: Un carburateur (12) comporte une cavité (24) communiquant avec le conduit d'admission (14) par un orifice secondaire (22). L'alimentation en un premier carburant (kérozène par exemple) comporte une première cuve à flotteur (30) placée par un ajutage (38) en communication avec la zone de dépression (18) et par un conduit (46) en communication avec la cavité (24). L'alimentation en second carburant (essence par exemple) comporte une seconde cuve à flotteur (50) desservant de son coté la cavité (24). En outre, une pompe d'amorçage (72) peut injecter du carburant secondaire par une arrivée (84) ménagée à cet effet en aval du papillon (20).
Patent BE-901446-A (BE)
Title: Procede de preparation d'alcaloides dimeres.
IPC: A61K31/475
Filed: 1985-01-04
Abstract: L'invention a pour objet la préparation d'alcaloides dimères de formule (II) dans laquelle R = méthyle ou formyle, ou d'un sel d'addition avec un acide de celui-ci. On oxyde une vinblastine à l'aide d'un oxyde de chrome (VI), d'un bichromate ou d'un ester alcoolique d'acide chromique dans un solvant quelconque, on convertit le composé obtenu dans lequel R = méthyle en sel d'addition et, éventuellement on oxyde ce sel à l'aide d'un agent oxydant et on convertit le composé dans lequel R = formyle en sel d'addition avec un acide. Utilisations courantes de ces alcaloides dans l'industrie.
Patent BE-902437-A (BE)
Title: Procede d'identification d'usagers d'un appareil telephonique.
IPC: H04M1/66
Filed: 1985-05-15
Abstract: L'appareil téléphonique (FA) contient un dispositif de codage (CE) qui est mis en activité par une clé (S) laissée à l'usager, et qui engendre, aprés décrochage du combiné, en dépendence du codage de la clé (S), un signe caractéristique d'identification de l'usager et qui l'envoie, par la ligne de raccordement (AL), au central téléphonique (VA), signe qui est mis en mémoire ensemble avec les données de chaque communication.
Patent BE-902970-A (BE)
Title: Procede d'etancheification d'un volume de stockage de dechets contenant des cations metalliques
IPC: E02D3/12
Filed: 1985-07-25
Abstract: Procédé pour créer un écran d'étanchéité autour d'un volume de stockage de déchets contenant des cations métalliques, qui consiste à injecter dans les vides du sol un coulis composé de proportions déterminées de ciment, d'argile et d'un produit siliceux, ainsi que d'un mélange destiné à retenir les cations de métaux lourds et formé de proportions définies de carbonate de sodium et d'un pyrophosphate de métal alcalin et (ou) d'un tartrate de métal alcalin.
Patent BE-905856-A (BE)
Title: Selecteur de monnaies electronique pour machines automatiques de distribution de produits.
IPC: G07D5/02
Filed: 1986-12-03
Abstract: Sélecteur de monnaies électronique pour machines automatiques de distribution de produits, qui présente la particularité de comporter un capteur (4) disposé sur le trajet des monnaies (3), de façon à mesurer le diamètre ou la section de la monnaie au passage de cette dernière en face du capteur; la monnaie passe ensuite à travers une bobine creuse (5) qui sert à déterminer l'alliage avec lequel est fabriquée la monnaie ainsi que le volume de cette dernière en se basant sur le paramètre mesuré antérieurement.
Patent BE-762148-A (BE)
Title: Continuous dyeing process for natural
IPC: D06P3/32
Filed: 1971-01-28
Abstract: Leather strips are sprayed with aniline and then passed through a passage through which hot air is blown. The pigment is then applied and the leather passed through a second passage through which hot air is blown.
Patent CA-1059632-A (CA)
Inventor: DOBRAS BRUCE W
IPC: G06K19/06
Filed: 1971-12-22
Granted: 1979-07-31
Abstract: CODED RECORD AND METHOD OF AND SYSTEM FOR INTERPRETING THE RECORD           Abstract of the Disclosure A machine-readable record or label includes alternating areas of different reflectivity providing a binary coded data record.  The record is made by selecting the widths of the areas such that an increase in the relative widths of any two consecutive areas of different characteristics represents a binary "1" and a decrease in the relative widths of any two consecutive areas represents a binary "0".  Thus, each area in the part of the code is used in the establishment of the values of two different binary bits.  A method of and a system for reading or interpreting the record or label includes a pair of light reader controlled registers in which are alternately stored the widths of consecutive areas.  A comparator coupled to the register determines whether each newly stored width is greater than or less than the width of the previously stored area.  In accordance with this determination, the comparator stores a "1" or a "0" in a shift register, the contents of which are transferred out as each complete character is received.
Patent CA-1044927-A (CA)
Inventor: ALESHIN VASILY A
IPC: B22F3/16
Filed: 1974-07-03
Granted: 1978-12-26
Abstract: ABSTRACT OF THE DISCLOSURE         A method of making filtering material from powdered steel wherein said powdered steel is cold rolled into strip and the latter undergoes a two-stage sintering process.  The material produced by this method is intended for filtering fluids such as liquid fuel or brake fluid and is capable of retaining mechanical particles of the order of 2-3 microns.
Patent CA-1042907-A (CA)
Inventor: WESTLEY JOHN
IPC: C07D307/12
Filed: 1975-04-01
Granted: 1978-11-21
Abstract: ABSTRACT     Halogen derivatives of the general formula   wherein X is selected from the group consisting of chlorine, bromine and iodine, and pharmaceutically acceptable salts thereof as well as their preparation.     The products have antibacterial and antiprotozoal properties.
Patent CA-1069878-A (CA)
Inventor: CHLUDZINSKI GEORGE R
IPC: C10M159/12
Filed: 1975-04-04
Granted: 1980-01-15
Abstract: ABSTRACT OF THE DISCLOSURE     Copolymers of ethylene and a C3 to C18 straight or branched chain. .alpha.-olefin, or terpolymers of ethylene, a C3 to C18 .alpha.-olefin and a C5 to C12 non-conjugated diolefin, or mixtures thereof, are dissolved in a mineral lubricating oil, and the solution oxidized with air or an oxygen-containing gas.  The oxidized solution, in which both the polymer and the oil have been oxidized, is reacted with an amine compound to form a polyaminox composition having utility as a dispersant additive for lubricants.  When made from high molecular weight polymers, the polyaminox composition is useful as a multi-functional dispersant-viscosity index improver additive for lubricants.
Patent CA-1081300-A (CA)
Title: Guiderails for drawers
Inventor: GRASS ALFRED
IPC: A47B88/12
Filed: 1975-04-23
Granted: 1980-07-08
Abstract: ABSTRACT OF THE DISCLOSURE                 The invention relates to a guide rail for drawers in which the rail is formed with lugs engaging grooves in the side walls of the drawer frame into which the lugs are introduced by a rotary motion of a tool for anchorage purposes.
Patent CA-1041272-A (CA)
Inventor: SHEPPARD ROBERT S
IPC: B01J19/08
Filed: 1975-06-11
Granted: 1978-10-31
Abstract: METHOD FOR PREPARING REFRACTORY METAL BORIDE POWDER                Robert S. Sheppard ABSTRACT OF THE DISCLOSURE     The preparation of refractory metal borides of Group 4b of the Periodic Table of the Elements by reaction in the vapor phase of the corresponding metal halide, e.g., metal chloride, with a boron source reactant in the presence of hydrogen in a reactor is described.  Reac-tants are introduced into a reactant mixing zone containing hydrogen through reactant inlet assembly means.  Refractory metal boride product deposits on the exposed surfaces of the reactant inlet assembly means are reduced significantly by introducing metal halide reactant and substantially anhydrous hydrogen halide into the hydrogen stream upstream of the boron source reactant while introducing boron source reactant mixed with inert carrier gas, e.g., argon, into said hydrogen stream downstream of the metal halide and hydrogen halide streams.