baber/WOPTO huggingface dataset:
Patent CA-2359657-A1 (CA)
Title: Microsensor housing
Inventor: BONNE ULRICH
IPC: G01N33/00
Filed: 2000-01-27
Abstract: A microsensor housing having a structure with at least one inlet at one end and a thermal property sensor at the other end. Situated between the inlet and the sensor is a convection shield. Sampled fluid is taken in the inlet from a channel carrying the fluid to be sampled. The convection flow lines of the fluid are barred by the convection shield. The fluid is diffused into a cavity between the shield and sensor. The sensor detects a thermal property of the diffused fluid. One preferred shield has holes about its perimeter with a solid center part of the shield covering at a distance the sensor. The channel carrying the fluid may have screens to reduce turbulence noise and to aid in fluid transport to and from the sensor housing.
Patent CA-2360223-A1 (CA)
Title: Method in connection with the production of paper or cardboard
Inventor: WERNER FREDRIK
IPC: D21D5/02
Filed: 2000-01-13
Abstract: A method in connection with the manufacturing of paper or cardboard in one or more plies in order to achieve a paper or cardboard product with an even and high quality, whereby a fibre composition of a paper or cardboard waste, so-called broke (7), is determined (4), whereafter the said broke is fractionated (5, 6) and at least one fibre fraction (8, 9, 10) obtained thereby is conveyed to a given ply in the paper or cardboard, whereby the said fractioning (5, 6) is controlled so that the fibre composition in the fibre fraction (8, 9, 10) obtained is adapted to a fibre composition in the input paper pulp (1, 2, 3) for the said given ply.
Patent CA-2362001-A1 (CA)
Title: Fishing reel
Inventor: WHITTLE-HERBERT GILES
IPC: A01K89/016
Filed: 1999-07-28
Abstract: This invention relates to a fishing reel (10) which comprises a reel body (12), a spool (14) rotatable relative to the reel body, a handle (16) for rotating the spool, and a drive bearing (32) connecting the handle to the spool. The drive bearing (32) is in the form of a ball-bearing including a plurality of balls (34) which are mounted to the handle (16) and which are arranged to rotate so that rotation of the handle (16) at a first velocity is transferred to the spool (14) at a second velocity greater than the first velocity.
Patent CA-2362662-A1 (CA)
Inventor: MCGUIGAN CHRISTOPHER
IPC: C07B53/00
Filed: 2000-02-10
Abstract: La présente invention porte sur des analogues de (1R, cis)-4-(6-amino-9H-purin-9-yl)-2-cyclopentène-1-méthanol, sur leurs procédés de préparation, et sur leur utilisation dans le traitement d'infections antivirales.
Patent CA-2364316-A1 (CA)
Title: Improved efficiency masked matching
Inventor: LIAO HENG
IPC: H04L29/06
Filed: 2001-12-03
Abstract: Methods and apparatus for reducing the search space processed by masked matching methods. The search space is reduced by grouping the candidate bit patterns into groups and subgroups that have internal bit agreement between the members. By only applying the mask matching methods to a select number of groups selected by their bit agreement with the target bit pattern, the computation time and memory requirement of the masked matching method is reduced.
Patent CA-2365890-A1 (CA)
Inventor: LOYD JAMES E
IPC: A61K9/14
Filed: 2000-03-17
Abstract: A method of delivering benzidene prostaglandins to a patient by inhalation i s discussed. A benzidene prostaglandin known as UT-15 has unexpectedly superio r results when administered by inhalation compared to parenterally administere d UT-15 in sheep with induced pulmonary hypertension.
Patent CA-2367544-A1 (CA)
Inventor: IGNASIAK BOLESLAW
IPC: C01F7/0606
Filed: 2002-01-08
Abstract: A method is provided for efficient processing of spent potliner, separating and recycling/utilizing the liquid and solid products generated during processing.  The method includes the steps of crushing and screening the potliner freed from metal debris, pulverizing the potliner suspended in a hot aqueous slurry by autogenous grinding in a tumbler in the presence of air, subjecting the potliner to a series of leaching, thickening and filtering steps followed by separation of the potliner into Bayer Liquor, solid sodium fluoride, quality carbon product and mineral matter characterized by low cyanide and fluoride leachability. About 85% of the water required for potliner processing is recovered and recycled into the process.
Patent CA-2368797-A1 (CA)
Inventor: HOY CYNTHIA A
IPC: C12P21/04
Filed: 2000-04-21
Abstract: A glycoprotein is produced by a process comprising culturing mammalian host cells expressing nucleic acid encoding said glycoprotein in the presence of (a) a factor that modifies growth state in a cell culture, (b) a divalent metal cation that can adopt and prefers and octahedral coordination geometry , and/or (c) a plasma component. In this process, the occupancy of an N-linked  glycosylation site occupied only in a fraction of a glycoprotein is enhanced . Such culturing is preferably carried out at a temperature of between about 3 0 ~C and 35 ~C and/or in the presence of up to about 2mM of a butyrate salt and/or in the presence of a cell-cycle inhibitor.
Patent CA-2370841-A1 (CA)
Title: Retroviral gene therapy vectors including insulator elements to provide high levels of gene expression
Inventor: ELLIS JAMES
IPC: C12N15/867
Filed: 2002-02-19
Abstract: Silencing of retrovirus vectors poses a significant obstacle to stem cell gene therapy, and may also impact stem cell marking and genetic manipulation studies. Retrovirus silencing is ameliorated but not eliminated by self inactivating (SIN) mutations. To overcome residual silencing using Insulator elements, we first developed a novel mammalian silencer-blocking assay. A human .beta.-globin transgene regulated by the Locus Control Region is silenced in transgenic mice when linked to retrovirus vector sequences. We show that dimer cHS4 core insulators flanking the .beta.-globin reporter completely block MSCV  retrovirus silencing in transgenic mice. These data distinguish silencer-blocking activity by cHS4 from its enhancer-blocking activity. Retrovirus vectors cannot be created at high titer with two internal dimer cHS4 cores. However, transgenic mouse silencer-blocking assays demonstrate that a combination of internal gypsy and dimer cHS4 cores cooperate to attenuate retrovirus silencing. EGFP retrovirus vectors with gypsy and the dimer cHS4 core increase expression from MSCV  transduced F9 Embryonic Carcinoma cells. The highest EGFP expression in F9 cells was produced by a high titer SIN retrovirus with gypsy in the LTRs. The silencer-blocking assay described here complements current enhancer-blocking and position-effect blocking assays. The gypsy insulated SIN retrovirus vector is well suited far gene therapy and for stem cell marking studies.
Patent CA-2372410-A1 (CA)
Title: Slurry composition and process for producing ceramic moulds
Inventor: LIU XING YANG
IPC: B22C1/16
Filed: 2002-02-19
Abstract: A ceramic mould slurry is disclosed for forming moulds and metal castings of improved surface quality. The slurry comprises a binder, a gelling agent, a first refractory material having a density of .RHO.1 and a mean particle size of .alpha.1, and a second refractory material having a density of .RHO.2 and a mean particle size of .alpha.2, wherein .RHO.1 > .RHO.2 and .alpha.1 < .alpha.2. The denser refractory material migrates downward through the slurry toward the upward-facing mould surface, thereby allowing formation of a smooth and accurate surface.
Patent CA-2375448-A1 (CA)
Title: Method for detecting syphilis using synthetic antigens
Inventor: POPE VICTORIA
IPC: G01N33/53
Filed: 2000-06-08
Abstract: An antigen composition and method for the detection of antibodies to Treponema pallidum and the diagnosis of syphilis are described. The antigen composition contains synthetic cardiolipin and synthetic lecithin. The antigen composition may additionally contain cholesterol and an alcohol. The antigen composition is useful as an immunoreagent in immunoassays for the detection of antibodies associated with T. pallidum infection. The methods are sensitive and specific for T. pallidum infection.
Patent CA-2375666-A1 (CA)
Title: Novel carboxylic acid derivatives comprising aryl-substituted nitrogen heterocycles, their production and their use as endothelin receptor antagonists
Inventor: AMBERG WILHELM
IPC: A61P9/04
Filed: 2000-05-19
Abstract: The invention relates to carboxylic acid derivatives of formula (I), whereby  the substituents have the meanings as explained in the description. The invention also relates to the production and use of said novel carboxylic ac id derivatives as endothelin receptor antagonists.
Patent CA-2378380-A1 (CA)
Inventor: TIAN YONG
IPC: G06F19/00
Filed: 2000-06-02
Abstract: An automated optical chip holder (10) of figure 1, for use in a pigtailing system precisely positions an optical chip at a predetermined location in three-dimensional space to aling the optical chip within the pigtailing system. The automated chip holder (10) includes an adjustable chuck assembly  (40) which moves optical chip (100) to a precise location in three dimension al space. Optical chip is disposed on a resilient pad and adjacent to a resilie nt wedge to protect the chip from damage durign clamping. The automated chip holder accommodates different sized optical chips without altering the size of the chuck assembly (40).
Patent CA-2379949-A1 (CA)
Title: Improved keratinocyte culture and uses thereof
Inventor: LIMAT ALAIN
IPC: A61K35/36
Filed: 2000-07-20
Abstract: The present invention relates to the treatment of skin defects by organotypically-cultured autologous keratinocytes isolated from the outer root sheath of anagen or growing hair. Methods for primary, as well as subsequent organotypic cultures (i.e., epidermal equivalents) in fully-defined media supplemented by autologous human serum and substances isolated form blood components, with minimal allogeneic biological supplements, are disclosed herein. Techniques to prepare epidermal equivalents for transplantation by use of a biocompatible glue are also disclosed herein.
Patent CA-2381676-A1 (CA)
Title: Intercooler
Inventor: ETO YOSHIHISA
IPC: F02B37/00
Filed: 2002-04-09
Abstract: In order to provide an intercooler assuming a simple structure that enables cooling of supercharging air and absorption of any expansion/contraction of the cooling water pipe and the casing attributable to the heat of the supercharging air, intake/outlet pipes of a heat exchanger housed inside a cooling space formed within a case are inserted at cylindrical pipe insertion portions formed at the case, any gap present between the intake/outlet pipes and the insertion portions are sealed by seal members each constituted of an elastic material formed in a staged cylindrical shape having a first cylindrical portion placed in complete contact with one of the pipe insertion portions and a second cylindrical portion placed in complete contact with either one of the intake/outlet pipes, which are also utilized to fit the heat exchanger in the case with a gap.
Patent CA-2383114-A1 (CA)
Title: Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
Inventor: ENSINGER HELMUT
IPC: C07D407/06
Filed: 2000-11-21
Abstract: The present invention relates to substituted 1,2,3,4,5,6-hexahydro-2,6-methano-benzazocines of general formula 1:     (see formula I) wherein the groups R1, R2, R3, R3', R4, R5, R6, X and A may have the meanings given in the specification and claims, processes for preparing them and their use as pharmaceutical compositions.
Patent CA-2385005-A1 (CA)
Inventor: PAGOWSKI STEFAN
IPC: B60J5/04
Filed: 2002-05-06
Abstract: An electric door operator is provided for controlling the opening and closing of a door pivotally mounted to a door frame of a multi-passenger mass transit vehicle. The electric door operator comprises a pinion and an energy source for rotating or driving this pinion in opposite directions through opening and closing cycles of the door. A gear sector is also provided which is mounted for rotation in an opposite direction from the pinion. The gear sector is engageable with the pinion and capable of being driven by the pinion such that it rotates in one of an opening and closing direction upon rotation of the pinion. A shaft member. having a first and second end is provided. The first end of the shaft member is secured to the gear sector and the second end of the shaft member is engageable with one of a base plate and a wall portion of the vehicle. A push bar is suspended from the gear sector for one of opening and closing the door upon rotation of the gear sector in one of the opening and closing directions.
Patent CA-2385174-A1 (CA)
Inventor: CIZDZIEL PHILIP
IPC: G01N21/33
Filed: 2002-05-07
Abstract: Reflectance based methods and devices are provided for determining the concentration of an analyte in a fluid sample. In practicing the subject methods, a fluid sample is applied to a matrix impregnated with a signal producing system. The signal producing system produces a detectable product in an amount proportional to the amount of analyte in the sample. A surface of the matrix is then illuminated and a reflectance measurement is obtained therefrom, generally following a predetermined incubation period. An optical component, preferably the illumination or light detection means, is also employed to obtain a temperature value corresponding to the ambient temperature of the matrix. The analyte concentration of the sample is then obtained from the reflectance measurement using an algorithm that employs the optical component derived temperature value. The subject methods and devices are suited for use in the detection of a variety of different types of fluid analytes, and are particularly suited for use in detecting the concentration of glucose in whole blood.
Patent CA-2385851-A1 (CA)
Title: Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms
Inventor: KLIMECKI WALTER
IPC: C12Q1/6837
Filed: 2000-09-22
Abstract: The present invention provides methods for detecting nucleic acid mutations and genetic polymorphisms by single base extension analysis. Specifically, t he invention provides an apparatus and methods for the detection of single base  extension of a particular oligonucleotide in an oligonucleotide microarray following hybridization between oligonucleotides bound to defined regions of  a polymeric hydrogel-based microarray and nucleic acids in a biological sample .
Patent CA-2391609-A1 (CA)
Title: Container for the collection of menstrual flow
Inventor: D ACCHIOLI VINCENZO
IPC: A61F5/44
Filed: 2000-12-01
Abstract: The present invention relates to a disposable menstrual fluid management device (10) including a bag (11) having an aperture (13) which is surrounded by an adhesively-faced flange (12) for releasable attachment to the uro-genital area of the wearer. An absorbent material (15) is contained within the bag. The device (10) effectively absorbs menstrual fluids whilst being comfortable and discrete to wear.
Patent CA-2393469-A1 (CA)
Inventor: BRUS RONALD HENDRIK PETER
IPC: A61K48/00
Filed: 2000-12-08
Abstract: A method of reducing the risk associated with administering adenoviral particles to subjects undergoing adenoviral gene therapy. An extremely low titer of adenovirus neutralizing antibodies is believed to lead to an acute virus-mediated cytotoxicity. Neutralizing antibodies prevent the hepatotoxic  effects of adenoviruses administered by way of the hepatic artery. An improv ed adenoviral gene therapy method of the type involving the administration, at a certain point in time, of recombinant adenoviruses containing a gene of interest to a subject wherein the improvement includes, before administering  the recombinant adenovirus containing the gene of interest, providing the subject with neutralizing antibodies directed to the recombinant adenovirus.  In one aspect of the method, the subject is provided with the antibodies by administering to the subject adenovirus of the same type as the recombinant adenovirus to be administered, at a before the administration of the recombinant adenovirus, to induce in the subject an immune response against the adenovirus. Alternatively, when insufficient time exists, or the subject  is immunocompromised, the subject is directly provided with the neutralizing  antibodies by administering, to the subject, antibodies directed against the  same serotype of adenovirus as the recombinant adenovirus or antibodies cros s- reactive with the serotype of the recombinant adenovirus. In such a case, th e antibodies are administered about one hour before the administration of the recombinant adenovirus containing the gene of interest. In this aspect of th e invention, human antibodies or humanized antibodies are particularly preferr ed to be administered parenterally to the subject.
Patent CA-2393843-A1 (CA)
Title: Circuit for dividing or bringing together high-frequency performances
Inventor: LUND MANUEL
IPC: H01P5/04
Filed: 2001-01-18
Abstract: The invention relates to an improved circuit for dividing or bringing together high-frequency performances. The inventive circuit comprises a main line (7) that is switched between an input and a first output port (1, 3) and a branch line (11) which branches off from the main line at a branch point (9) and leads to a second output port (5). The inventive circuit is characterised in that a balancing element (61) which is especially adjustable or can be especially built in or re-moved in different ways is provided. Said element can be changed by changing the capacity of at least one capacitor (C1, C2, C3) which is switched in the branch line (11) and/or by changing the electric length of a spur line (37) which is coupled to the branch line (11), in such a way that the resistance change that is caused by the changed performance division can be compensated when the variable of the branched off performance is changed.
Patent CA-2397857-A1 (CA)
Inventor: TAO YE
IPC: H01L27/32
Filed: 2002-08-13
Abstract: A method of making an organic light emitting device (OLED) is disclosed wherein an inert insulating conformal smoothing layer is deposited over a protruding structure. The smoothing layer is patterned to expose portions of the structure underlying the smoothing layer and defining active regions of the device. The inert smoothing layer is treated, preferably by heat reflow, to taper the layer over the stepped edges of the structure on the exposed portions. Additional layers are then deposited over the smoothing layer and the exposed portions of the structure. The smoothing layer blunts all underlying layer edges and provides sloped edges wherever a step occurs from one layer to another.  This effect results in a homogeneous field across the pixel and the continuity in the layers deposited after the photoresist layer.
Patent CA-2399016-A1 (CA)
Title: Improved system and method for implementation of an echo canceller
Inventor: GUPTA SAMIR K
IPC: H04M9/08
Filed: 2001-01-26
Abstract: A system and method for cancelling an echo signal. An input waveform is provided to an acoustic processor, and a determination is made whether the input waveform includes information representative of an echo signal. If the input waveform includes information representative of an echo signal, an output waveform is formed by attenuating a residual waveform with the acoustic processor. The residual waveform is attenuated by an attenuation factor that gradually changes from an initial attenuation value to a final attenuation value during the attenuation step. A system and method for adjusting an acoustic signal from a muted state to an unmuted state by varying an attenuation factor applied to an acoustic signal by an acoustic processor. The acoustic signal is provided to an acoustic processor. An output waveform is formed from the acoustic processor by adjusting the attenuation factor from a muted state to a first attenuation value associated with the non-muted state. After the attenuation factor is adjusted to the first attenuation value, the output waveform is formed by gradually changing the attenuation factor from the first attenuation value to a second attenuation value. The input waveform is attenuated by a smaller amount when the second attenuation value is applied to the acoustic signal than when the first attenuation value is applied to the acoustic signal.
Patent CA-2399166-A1 (CA)
Inventor: KASAGI TSUKASA
IPC: F24F5/00
Filed: 2002-08-16
Abstract: In order to provide a gas heat pump type air conditioning device in which accessibility and maintenance operation are not disturbed due to snow in snowy areas, a gas heat pump type air conditioning device comprises a compression device (11) for which the driving source is a gas engine and forms a refrigerating cycle by circulating a refrigerant, a bypass pipe channel section (80) which is provided around space where an outdoor unit is installed and is separated from an engine-coolant-water system (30) of the gas engine via a channel change switching device (81), wherein waste heat exhausted from the gas engine is collected back into the engine-coolant-water, and the refrigerant is heated by the engine-coolant-water so as to enhance air heating capacity.
Patent CA-2399790-A1 (CA)
Inventor: ANDERSON LARRY J
IPC: A61K39/39
Filed: 2001-02-02
Abstract: La présente invention concerne des méthodes et des adjuvants destinés à intensifier une réponse immunitaire dirigée contre le virus RSV chez un hôte, ces méthodes et ces adjuvants comprenant une source d'une protéine de liaison CD40. Cette protéine de liaison CD40 est de préférence CD40L, la source étant un vecteur comprenant un promoteur fonctionnellement relié à une région de codage CD40L. La réponse immunitaire intensifiée produite par les adjuvants et les méthodes de la présente invention implique une augmentation de l'expression des cytokines Th1 et de la production d'anticorps.
Patent CA-2401492-A1 (CA)
Title: Method for making, loading and sealing a cell or drug encapsulation device, and such a device
Inventor: HUBBARD TERRY A
IPC: A61K45/00
Filed: 2001-02-26
Abstract: A wet seal method and apparatus for use in biologically implantable containment devices, the devices adaptable for drug formulations or cell suspensions. A porous membrane, in a tubular configuration, is formed and can be configured as part of a closed cell-tight system for loading.      During loading, the containment device membrane is wet, while the loading system remains cell-tight. The containment device is sealed through a combination of heat and pressure, while the system remains cell-tight. Sealing the containment device substantially or completely eliminates metabolic functioning of any organisms in the vicinity of the closure. The seal is formed by melting a thermoplastic material that is in contact with the membrane. The containment device is separated from the cell-tight loading system, which remains closed after separation.
Patent CA-2405739-A1 (CA)
Inventor: BARANI MOE K
IPC: F04B1/04
Filed: 2001-04-13
Abstract: The invention provides a variable speed hydraulic pump designed to operate at a maximum horsepower throughout its pressure range by adjusting motor speed according to motor load parameters. In particular, the variable speed hydraulic pump includes a hydraulic pump unit coupled to a variable speed electric motor by a drive unit and to a hydraulic fluid tank for pressurizing and pumping hydraulic fluid when operated by the motor. A motor controller is electrically connected to the motor to supply drive signals to the motor based on electrical characteristics of the drive signals which are dependent on the load exerted on the motor. Suction from the load is provided by both the main pump and a bidirectional supercharging pump by reversing the direction of the motor and shifting a 4/3 valve to connect the main pump inlet to the load and its outlet to tank. In addition, the controller reduces the motor speed at the maximum rated pressure to just maintain the pressure, to reduce the amount of fluid pumped through the maximum pressure relief valve.