baber/WOPTO huggingface dataset:
Patent JP-3140566-B2 (JP)
IPC: C07D239/47
Filed: 1992-07-06
Granted: 2001-03-05
Abstract: The present invention relates to the derivatives of formula: <IMAGE> Formula (I)  as well as to their addition salts and to their use in therapy, in particular for the treatment of cardiovascular diseases, especially for the treatment of hypertension, cardiac insufficiency and diseases of the arterial wall.
Patent JP-H0447689-B2 (JP)
IPC: C08K5/00
Filed: 1986-08-28
Abstract: Flexible polyurethane foams having improved electrostatic properties are prepared by incorporating into the reaction mixture before foaming an antistatic additive composition comprising a blend of a quaternary ammonium compound selected from soya dimethyl-ethyl-ammonium-ethylsulphate, soya dimethyl-ethyl-ammonium-phosphate and mixtures thereof and a plasticiser selected from N-ethyl-o- and p-toluene-sulphonamides, o- and p-toluene-sulphonamides, and tetrakis (2-chloroethyl)-ethylene- diphosphate and mixtures thereof.
Patent JP-2897152-B2 (JP)
IPC: G01N21/77
Filed: 1993-08-20
Granted: 1999-05-31
Abstract: The subject-matter of the invention is an analytical element for determination of an analyte in the form of a light-transmitting stylus (pin) having a lateral surface and two essentially parallel end faces. One of the end faces carries a reagent which participates in the presence of the analyte in an optically detectable reaction. The lateral surface has a projecting element. The subject-matter of the invention is, moreover, a method for producing an analytical element according to the invention, and a method for determining an analyte by means of an analytical element according to the invention.
Patent JP-H0327552-B2 (JP)
IPC: C07D501/20
Filed: 1987-08-31
Abstract: A compound of the formula:whereinR' is amino or a protected amino group;R<sup>2 </sup>is a saturated 4 to 8-membered heteromonocyclicgroup containing one sulfur atom;R<sup>3</sup> is carboxy or a protected carboxy group; andR' is hydrogen, lower alkyl, or a group of the formula:[wherein R" is acyloxy, a heterocyclicthio group which may have suitable substituent(s) or pyridinio which may have suitable substituent(s)], with proviso that R<sup>3</sup> is COO when R" is pyridinio which may have suitable substituent(s), and pharmaceutically acceptable salts thereof, and processes for their preparation and also a pharmaceutically composition comprising, as an effective ingredient, the above compound in association with pharmaceutically acceptable carriers.
Patent JP-4771568-B2 (JP)
IPC: C04B35/195
Filed: 1999-08-05
Granted: 2011-09-14
Abstract: A plasticizable raw material mixture for use in preparing a substrate having cordierite as its primary phase with the mixture comprised of a chemical composition, percent by weight, of 11 to 17% MgO, 33 to 41% Al2O3 and, 46 to 53% SiO2. The raw material mixture specifically comprises the following: (1) one source of Al2O3 and SiO2 comprising a clay mixture having less than about 22 %, by weight based on the total raw materials in the plasticizable mixture, of calcined clay; (2) an alumina yielding precursor comprising alumina having an average particle diameter of about 1 mu m or less; and, (3) at least one source of magnesia having an average particle diameter of between about 3 to 15 microns. This invention additionally relates to a method of producing a green body of cordierite-forming materials comprising preparing a plasticizable raw material mixture of the aforementioned composition, adding an organic binder system to the mixture and mixing the mixture to form an extrudable mixture, and extruding the mixture to form a substrate of the desired configuration. The green body is dried and fired to yield a ceramic substrate having cordierite as its primary phase. <IMAGE>
Patent JP-2703574-B2 (JP)
IPC: A61K47/48
Filed: 1988-09-29
Granted: 1998-01-26
Abstract: A method for suppressing the reproduction capacity of a mammal by stimulating the immune system thereof in order to raise antibodies which bind to the natural GnRH of the mammal comprises using a stimulating agent which is obtained by conjugating
 a) a GnRH molecule in which one or more of the ten naturally occurring amino acids is replaced by another amino acid with a more reactive side chain to
 b) an immunostimulant carrier molecule.
Patent JP-2970909-B2 (JP)
IPC: A61L15/16
Filed: 1988-10-05
Granted: 1999-11-02
Abstract: A wound dressing having high adsorbency for bacterial toxins and the like comprises a layer of activated carbon wherein at least 10% of the pore volume of the activated carbon is represented by mesopores. The mesoporous activated carbon may be made by impregnating a cellulosic fibrous material with a liquid medium containing phosphate and an alkali metal, then carbonising and activating the impregnated fibrous material by heating in a suitable atmosphere.
Patent JP-2642089-B2 (JP)
IPC: C07J41/00
Filed: 1995-09-07
Granted: 1997-08-20
Abstract: Bile acid derivatives of the formula I  W-X-G in which G is a bile acid residue, W is an active substance portion of a medicament and X is a linker between bile acid residue and active substance portion, are outstandingly suitable for introducing active substances into the enterohepatic circulation. The compounds I are absorbed and enter the bloodstream. This makes it possible by utilising the natural reabsorption of the bile acids to improve the absorption of drugs which are absorbed with difficulty, if at all. W can be, for example, a peptide, an antibiotic, an antiviral substance, an anticancer agent, a liver protective, an antihyperlipidaemic, a diuretic, an agent to lower blood pressure, a renin inhibitor, a substance to treat cirrhosis of the liver or a substance for treating diabetes. G is a bile acid residue in the form of the free, natural or chemically modified acids, the esters and amides, the salt forms and forms derivatised on alcohol groups. X is a large number of intermediate members or else a bond.
Patent JP-H0680004-B2 (JP)
IPC: A61K8/35
Filed: 1984-12-11
Abstract: A cosmetic preparation contains, as a fatty phase, karite oil having the following characteristics: palmitic acid (C16), 3-5 percent; stearic acid (C18), 22-30 percent; oleic acid (C18:1), 55-65 percent; linoleic acid (C18:2), 0.5-1.5 percent; and arachidic acid (C20), 0.5-1.5 percent, said percentages being based on the total weight of fatty acid present in said karite oil, a viscosity of 100-300 centipoises, a melting point of 5.1 DEG -5.4 DEG  C., a crystallization temperature of 2.9 DEG -3 DEG  C. and an unsaponifiable content of 1.2-1.5 percent.
Patent JP-3057012-B2 (JP)
IPC: F23N5/20
Filed: 1996-10-07
Granted: 2000-06-26
Abstract: The burner utilises a hot surface ignition with an ignitor that is fully sintered and has essentially no porosity. A circuit applies an AC line voltage to the ignitor and to a blower motor. An AC-to-DC converter provides twelve volts DC for operation of a control circuit that has a first time constant circuit for preheating the ignitor and maintaining the ignitor at an ignition temperature for a predetermined ignition trial period of time. A second time constant circuit starts the blower motor and provides fuel to the combustion chamber for a predetermined time concurrent with the ignition trial period. A third time constant circuit either maintains the fan blower in its energised state if a flame of sufficient magnitude and frequency is detected and for de-energising the blower motor if the flame is not detected in less than one second after the ignitor is de-energised.
Patent JP-H0772235-B2 (JP)
IPC: C07D221/00
Filed: 1986-11-25
Abstract: Novel diazaspirodecanes of the general formula   <IMAGE>   are prepared from known diazaspirodecane compounds and epoxy compounds or by reacting diazaspirodecane-substituted epoxy compounds with alcohols or amines and are excellent light stabilizers for synthetic polymers.
Patent JP-2656095-B2 (JP)
IPC: B32B27/06
Filed: 1988-11-30
Granted: 1997-09-24
Abstract: In the manufacture of packing containers by means of folding of laminate in the form of sheets or of a web of the type which comprises a relatively thick carrier layer (2) of paper or cardboard and a gas-tight, thin metal foil (5) the laminate is subjected to stresses which, particularly within folding regions comprising multiple material thicknesses, may be so strong that crack formations occur in the metal foils protecting against gas which are sensitive to tension, thus entailing the risk of the intended gas barrier characteristics of the packing container being impaired or wholly lost. To counteract this risk the packing laminate is provided with a layer (6) of ethylvinyl alcohol laminated between the metal foil (5) and the carrier layer (2) which for one thing is mechanically sufficiently durable to withstand the external stresses during the folding of the laminate, and for another has sufficiently good gas barrier properties to compensate for the loss in gas tightness which thus may arise if the integrity of the metal foil (5) is lost during manufacture of the container. Preferably the laminate is provided also with a further layer (7) of a material permeable to moisture which is laminated between the ethylvinyl alcohol layer (6) and the carrier layer (2) and which is adapted to let through moisture which from the liquid-filled inside of the container might be able to penetrate into the ethylvinyl alcohol layer (5) through such crack formations in the metal foil (5). As a result the moisture content on the ethylvinyl alcohol layer (6) can be kept at a sufficiently low level so as not to have a negative effect on the gas barrier characteristics of the ethylvinylalcohol layer (6) which otherwise diminish with increasing moisture content.
Patent JP-3383625-B2 (JP)
IPC: A01B63/10
Filed: 1999-12-24
Granted: 2003-03-04
Abstract: The way valve (33) of each bottom rod cylinder unit (11) has two connections (31,32) to the cylinder notably to piston (23,23a) and rod (24,24a) spaces and a third connection (34,34a) to pressure (P) and a fourth (36,36a) to the return (37,37a). All connections are closed off in the first valve (33) position and in the second position, the cylinder piston side (23,23a) connects to pressure (P) as opposed to the rod side (24,24a) connected to return. In the third position of the valve, the rod side (24,24a) is pressurized and the piston side (23,23a) joins to return. A circuited switching unit (28,28a) contains one input fed with value (F) corresponding to the ideal bottom rod setting, and a second input fed with the position pickup (25) signal showing the current rod position. The unit (28,28a) uses its comparator (27,27a) to compare value (F) with the current position signal and from this switches the valve into one of its three settings accordingly.
Patent JP-H07104227-B2 (JP)
IPC: G02B6/00
Filed: 1988-12-22
Abstract: Apparatus for measuring the endface angle of a cleaved optical fibre (1) includes a light source (3) for injecting optical energy into that end (1a) of the optical fibre (1) opposite to that whose endface angle is to be measured. Means are provided for tapping optical energy passing along the optical fibre (1) in both directions. Photodetectors (5,6) measure the signal strength of the optical energy tapped from the optical fibre (1) in both directions. The ratio of these measured signal strengths is compared with a known relationship between endface angles and the ratio of said measured signals to provide a measure of the endface angle.
Patent JP-3431142-B2 (JP)
IPC: G01N30/06
Filed: 1992-06-15
Granted: 2003-07-28
Abstract: The invention features a method of detecting a trace solute in a solution which contains a major amount of a dissolved product, the method including the steps of: flowing the solution through means for extracting the product to produce an effluent flow substantially free of product containing the trace solute; flowing the effluent through a trace solute adsorbing means to progressively accumulate therein the trace solute; and eluding the trace solute from the adsorber to produce an eluant fraction containing a detectable quantity of the trace solute.
Patent JP-2877513-B2 (JP)
IPC: G02C13/00
Filed: 1990-12-18
Granted: 1999-03-31
Abstract: Ophthalmic compositions, such as those used to care for contact lenses, methods of preserving such compositions, and methods for disinfecting contact lenses using such compositions are disclosed. The compositions may comprise an ophthalmically acceptable, liquid aqueous medium and, included therein, an effective preserving or disinfecting amount of certain oxygen-containing ionene polymers.
Patent JP-2571561-B2 (JP)
IPC: C21C1/02
Filed: 1985-10-30
Granted: 1997-01-16
Abstract: The refining additive is an alloy in the form of granules of a metal selected from the group of alkaline earth metals and zinc with a small quantity of a metallic element capable of giving the alloy a substantially lower melting point. The alloy can be a eutectic alloy. This alloy, which is in the form of granules, allows the treatment of steels, cast iron and non-ferrous metals at lower temperatures and with a substantial reduction in bubble formation. The alloy may be introduced in the form of a core wire.
Patent JP-2760899-B2 (JP)
IPC: B22D41/50
Filed: 1992-08-31
Granted: 1998-06-04
Abstract: A non-reversible plate having a depending tube structure with a discharge opening at the bottom in which there is a plate at the upper portion, rectangular in configuration, and which has an irregular anti-reversal collar beneath the plate portion is disclosed. Desirably the collar is elliptical in configuration and has a major axis at least seven millimeters longer than the minor axis. The longer axis is parallel with the length dimension. Another aspect of the invention is the utilization of a toggle actuated plate changing device which swings in and out of position and can only be actuated when the plate and tube intended for insertion presents the length for insertion into the valve structure. Suitable microswitch or related device is provided to permit actuation of the change actuator, but only when the plate is properly oriented for insertion. The method of the present invention includes the steps of pre-orienting and proportioning a tube or shroud having a plate at the upper portion for insertion into a plate changer assembly.
Patent JP-H0827432-B2 (JP)
IPC: G02B6/12
Filed: 1986-10-16
Abstract: The invention relates to the mounting of a movable member such as an optical mirror (3) by bridges (4-7) between a pair of supports (1,2). The supports (1,2), bridges (4-7) and mirror (3) are integrally formed from a silicon substrate. A pair of electrically conductive paths (8,9) are formed by doping or metallising portions of the assembly so that by passing controlled currents through the paths, thermal expansion of parts of the paths will cause deflection of the mirror (3). The assembly is particularly useful for deflecting optical beams.
Patent JP-3941883-B2 (JP)
IPC: C07K1/12
Filed: 1996-07-12
Granted: 2007-07-04
Abstract: PCT No. PCT/EP96/03073 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/05162 PCT Pub. Date Feb. 13, 1997A process for preparing pentapeptides of the formula I where A and R1-R3 have the stated meanings, comprises assembling the pentapeptide stepwise starting from a prolinamide of the formula II where R1 and R2 have the abovementioned meanings, and eliminating the group -NR1R2 by hydrolysis where appropriate the peptide obtained in this way.
Patent JP-H0436026-B2 (JP)
IPC: A61M5/31
Filed: 1989-09-29
Abstract: The needle assembly has a hub (3) with a needle (5) attached at one end and a tube (7) attached at the opposite end. The hub (3) has a pair of wings (3a), which can be taped to a patient to hold the needle in place. The needle and hub (5,3) are slidably enclosed in a guard (1) with the wings (3a) engaged in slots (1c) in the guard to facilitate extension or retraction of the needle. The guard has a locking member (1i,1h), which engages the wings to lock the needle in the fully retracted position. <IMAGE>
Patent JP-3396224-B2 (JP)
IPC: C12N1/15
Filed: 1996-09-12
Granted: 2003-04-14
Abstract: A promoter of a formate dehydrogenase gene of C. boidinii which substantially contains a consecutive base sequence of 190 bp or more picked out in the base sequence represented by SEQ ID NO: 1 in the Sequence Listing; a formate dehydrogenase gene promoter which substantially contains a base sequence represented by SEQ ID NO: 1, 48, 49 or 50; a formate dehydrogenase gene terminator which substantially contains the base sequence represented by SEQ ID NO: 2; a gene expression cassette which comprises the above-mentioned promoter, a foreign gene and the above-mentioned terminator; a recombinant expression vector which contains this gene expression cassette; a product of transformation with this recombinant expression vector; and a process for producing a foreign gene expression product which comprises incubating the transformant in a medium and taking up the foreign gene expression product from the culture medium thus obtained.
Patent JP-3197900-B2 (JP)
IPC: B01D61/18
Filed: 1993-01-08
Granted: 2001-08-13
Abstract: The invention employs dual-skinned membranes useful as one way or rectifying membranes which reduce back filtration of solute molecules in dialysis and which improve nutrient supply and product recovery in membrane bioreactors. The membranes are dual-skinned polymeric materials preferably in the form of hollow fibers. The membranes have sieving coefficient characteristics different for flow of liquids in one direction from that in the opposite direction. Improved dialysis devices are formed by using bundles of the hollow fiber membranes as a dialysis means having rectifying properties. Improved bioreactors are formed by using bundles of hollow fiber as a growth vessel having rectifying properties.
Patent JP-2824332-B2 (JP)
IPC: C12N5/00
Filed: 1993-04-16
Granted: 1998-11-11
Abstract: The present invention provides novel plasmids, transfected eucaryotic cells and methods of producing these plasmids and transfected eucaryotic cells. The novel plasmid contains the cDNA for human lactoferrin protein. Methods for the production of human lactoferrin protein in A. Oryzae are also provided. Thus, the present invention provides an efficient and economical means for the production of recombinant human lactoferrin protein.
Patent JP-4124482-B2 (JP)
IPC: C12N15/02
Filed: 1996-11-26
Granted: 2008-07-23
Abstract: The present invention relates to methods and compositions that can be employed to introduce toxins and nucleic acids into the cytoplasm or nucleus of a eukaryotic cell, particularly a cell of a higher vertebrate. The invention particularly concerns the use of a fusion protein of streptavidin and protein A sequences to form a non-covalent complex of a toxin or nucleic acid and an antibody.
Patent JP-4122052-B2 (JP)
IPC: A61K31/702
Filed: 1995-02-09
Granted: 2008-07-23
Abstract: This invention relates to treatment of antibiotic associated diarrhea, including Clostridium difficile associated diarrhea (CDAD) and pseudomembranous colitis (PMC), using oligosaccharide compositions which bind C. difficile toxin A. More specifically, the invention concerns neutralization of C. difficile toxin A associated with CDAD.
Patent JP-3549536-B2 (JP)
IPC: C12N15/12
Filed: 1994-05-10
Granted: 2004-08-04
Abstract: The present invention provides an in vitro cell culture system, based on neuronal cells comprising oncogenic derivatives of the NGF-receptor gene NTRK1, and exhibiting NGF-independent neuronal differentiation closely resembling NGF-induced cellular responses in normal cells, but differing from these responses by displaying cellular degeneration after prolonged culture periods. The present invention furthermore provides eukaryotic expression vectors containing cDNAs coding for the NTRK1-derived oncoprotein TRK-T1, and a method to obtain said neuronal cells by transformation with eukaryotic expression vectors coding for oncogenic derivatives of NTRK1.
Patent JP-3185059-B2 (JP)
IPC: F27B15/08
Filed: 1996-12-28
Granted: 2001-07-09
Abstract: A fluidized bed reducing system for reducing a fine iron ore is disclosed, in which the structure of the fluidized bed reducing furnace is improved such that the coarse iron ore particles are distributed in the lower portion of the fluidized bed within the furnace and the fine iron ore particles are distributed in the upper portion of the fluidized bed. Thus, the average residence times of the particles in the furnace are adjusted differently for different ore sizes, so that the reducing efficiency can be improved, and that the residence time of the reducing gas in the furnace can be extended, thereby improving the degree of gas utilization. The fluidized bed reducing system for reducing a fine iron ore includes: an upper iron ore outlet for discharging fine iron ore particles; a lower iron ore outlet for discharging coarse iron ore particles; a gas distributor installed in a lower portion of a reducing furnace; a gas inlet formed on a lower portion of the reducing furnace for introducing a reducing gas; an iron ore inlet for supplying an iron ore of wide particle size distribution; a circulating duct connected to an upper portion of the reducing furnace for discharging extremely fine iron ore particles together with the reducing gas; a particle capturing device an extremely fine iron ore recycling duct. The fluidized bed reducing furnace includes a cylindrical upper portion and a tapered lower portion, the tapered portion being in a wide-upper-narrow-lower shape.
Patent JP-3816522-B2 (JP)
IPC: A61K47/18
Filed: 1996-04-05
Granted: 2006-08-30
Abstract: A pharmaceutical composition for stimulating the haematopoietic function and preventing the myelotoxic side-effects of some treatments, containing at least one water-soluble muramyl peptide derivative such as Muradimetide, muroctasine or MTP-PE.
Patent JP-3875278-B2 (JP)
IPC: B02C15/06
Filed: 1997-04-15
Granted: 2007-01-31
Abstract: A grinder constituted by a ring (10) having a horizontal axis, a mechanism for driving the ring in rotation about its axis, at least one roller (16) the axis of which is parallel to that of the ring and which is placed inside the latter so as to be able to travel over its internal surface and elastic member (30) for pressing the roller against the ring, the roller being supported at its ends by two arms (22) mounted on the frame of the grinder so as to be able to pivot about an axis parallel to the axis of the ring.
Patent JP-4125795-B2 (JP)
IPC: C08L75/04
Filed: 1998-05-08
Granted: 2008-07-30
Abstract: The invention provides a process for preparing flexible to semi-rigid polyurethane moulded items with compacted edge zones with given hardness and a much more flexible cellular core, so-called integral foams, in which physical blowing agents from the set comprising C6 hydrocarbons are used.
Patent PL-162383-B2 (PL)
Title: Material for making building units thereof
Inventor: WARZYBOK TADEUSZ
IPC: C04B38/06
Filed: 1990-06-15
Abstract: 1. Material for producing building elements of construction and insulating characteristics containing Portland cement of the brand of at least "35", clay and water characterised in that 1 m<3> of the material contains: 150-260 kg of cement, 400-500 kg of medium-fat clay or fatty clay of weight by volume of 1280-1420 kg/m<3>, 90-250 kg of chaff from wheat straw or triticale straw, or their mixture, and 250-350 l of water.
Patent ES-2188361-B2 (ES)
Title: Maquina para cortar pizarra de forma irregular.
Inventor: LOPEZ VIDAL ANA ISABEL
IPC: B28D1/32
Filed: 2001-04-04
Granted: 2003-12-16
Abstract: Máquina para cortar pizarra de forma irregular; que comprende una mesa giratoria (1) accionada por un motor (2) que comporta radialmente varios brazos (3), que en extremo montan platos (4) soporte de una pieza de pizarra, efectuando dicha mesa un recorrido circular, deteniéndose en posiciones fijas que se corresponden con una inicial de carga, otra final de expulsión y diversas estaciones de trabajo intermedias.