baber/WOPTO huggingface dataset:
Patent IL-100867-A0 (IL)
Title: Method and apparatus for improved luminescence assays
IPC: G01N33/553
Filed: 1992-02-04
Abstract: The invention relates to an apparatus for performing a binding assay for an analyte of interest in a sample based upon measurement of electro-chemiluminescence at an electrode surface comprising an electrochemical cell having a sample-holding volume, inlet and outlet means; a working electrode system to provide electrochemical energy to trigger electrochemiluminescence; a voltage control device to supply voltage signals to the working electrode system; a magnet placed in proper orientation and in close proximity to the working electrode so that magnetically responsive particles will concentrate on the surface of the working electrode; a light detection/measurement device for measuring electrochemiluminescence triggered at the electrode surface; and a pump to provide for fluid transport to, through and from the electrochemical cell. The apparatus may be used in an electrochemiluminescence assay for an analyte of interest in which magnetically responsive particles are magnetically collected on the electrode surface and emitted electrochemiluminescence is measured using the light detector. <IMAGE>
Patent IL-115084-A0 (IL)
Title: Carbamoylcarboxamides their preparation and use
IPC: C07C323/50
Filed: 1995-08-28
Abstract: PCT No. PCT/EP95/03303 Sec. 371 Date Mar. 3, 1997 Sec. 102(e) Date Mar. 3, 1997 PCT Filed Aug. 19, 1995 PCT Pub. No. WO96/07638 PCT Pub. Date Mar. 14, 1996Carbamoylcarboxamides of the general formula I    <IMAGE>  (I)  and their salts (R1 is unsubstituted or substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl or an unsubstituted or substituted nonaromatic carbo- or heterocycle; R2 is H or unhalogenated or halogenated alkyl or cycloalkyl; R3 is unsubstituted or substituted alkyl, cycloalkyl or phenylalkyl; R4 is H or one of the radicals R3 or R3 and R4, together with the C atom to which they are bonded, are an unsubstituted or substituted carbo- or heterocycle; R5 independently of these is one of the radicals R2; X independently of one another is hydrogen, unsubstituted or substituted alkyl and/or alkenyl; Y independently of one another and of these is one of the radicals X; p,q independently of one another are 0, 1 or 2; R6 is halogen, cyano, nitro or unsubstituted or substituted alkyl, alkoxy, alkylthio or an unsubstituted or substituted phenyl group bonded via oxygen or sulfur; r is 0, 1, 2 or 3), and compositions containing them, processes for preparation, and the use of the compounds I and the compositions are described.
Patent IL-116599-A0 (IL)
Title: Topical pharmaceutical compositions
IPC: C07D487/22
Filed: 1995-12-28
Abstract: A topically administrable pharmaceutical composition comprising (A) zinc phthalocyanine, (B) as carrier for (A), (i) a monoalkyl ether of diethyleneglycol substantially in the absence of a N-alkylpyrrolidone, a N,N-dialkylbenzamide or dimethyl sulphoxide, or (ii) a mixture of a monoalkyl ether of diethyleneglycol with a lipid and (C) a gelling agent.
Patent IL-123417-A0 (IL)
Title: Unactivated oocytes as cytoplast recipients for nuclear transfer
IPC: C12N15/877
Filed: 1996-08-30
Abstract: A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at the time of transfer, so that the donor nucleus is kept exposed to the recipient cytoplasm for a period of time. The diploid nucleus can be donated by a cell in either the GO or G1 phase of the cell cycle at the time of transfer. Subsequently, the reconstituted embryo is activated. Correct ploidy is maintained during activation, for example, by incubating the reconstituted embryo in the presence of a microtubule inhibitor such as nocodazole. The reconstituted embryo may then give rise to one or more live animal births. The invention is useful in the production of transgenic animals as well as non-transgenics of high genetic merit.
Patent IL-123455-A0 (IL)
Title: Stable fabric softener compositions
IPC: D06M15/507
Filed: 1996-08-19
Abstract: Fabric softening compositions which form and maintain stable aqueous dispersions in the absence of added oily perfume are disclosed. The stability of aqueous fabric softener compositions based on a mixture of an amido amine, such as bis(tallow amidoethyl)-2-hydroxyethyl amine and a quaternary diester fabric softener, such as N-methyl, N,N,N-triethanolamine ditallow ester quaternary ammonium salt is enhanced by inclusion in the composition of at least one fatty ester of a fatty acid or fatty alcohol, e.g., glycerol monostearate.
Patent IL-130482-A0 (IL)
Title: Positive flow valve
IPC: A61M5/00
Filed: 1997-12-15
Abstract: A closed system, spikeless, positive-flow valve device includes a body defining an internal cavity. At the proximal end of the body is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The valve includes a plastic, resilient silicon seal which fills the upper cavity and opening with an oval seal cap having a slit. The opening presses the oval seal cap to keep the slit closed in the decompressed state. The slit opens as the nose of the medical implement compresses the seal into the cavity and the seal cap is free from the opening. The housing also includes a fluid space which facilitates fluid flow between the medical implement and a catheter tip. The fluid space within the valve automatically and reversibly increases upon insertion of the medical implement into the cavity and decreases upon withdrawal of the medical implement, such that a positive flow from the valve toward the catheter tip is effected upon withdrawal of the medical implement, thereby preventing a flow of blood from a patient into the catheter when the medical implement is removed from the valve.
Patent IL-134594-A0 (IL)
Title: Polymorphs of 2-(3-cyano-4-isobutyloxphenyl) -4-methyl-5-thiazolecarboxylic acid and methods of producing the same
IPC: C07D277/56
Filed: 1999-06-18
Abstract: The present invention provides a technique of selectively producing a desired polymorph of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid.  The present invention also provides a method of producing various polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, which comprises crystallizing under the conditions defined by a specific temperature and a composition of a mixed solvent of methanol and water, and polymorphs obtained by the method.  The present invention further provides a method of producing the other polymorphs or amorphous compounds by drying a specific polymorph under a reduced pressure with heating, and the other polymorphs or amorphous compounds obtained by the method.
Patent IL-135733-A0 (IL)
Title: Encapsulation method
IPC: A61K31/7064
Filed: 1998-09-24
Abstract: A novel method of encapsulating an active substance in a biodegradable polymer, which comprises: a) dissolving said biodegradable polymer in an organic solvent therefor; b1) dispersing said active substance in the organic solution obtained in step a) to provide a dispersion with the active substance as the inner phase thereof; or alternatively b2) emulsifying said active substance, dissolved in water or other aqueous solvent therefor, in the organic solution obtained in step a) to provide an emulsion with the active substance as the inner aqueous phase thereof; and c) subjecting the dispersion obtained in step b1), or alternatively the emulsion obtained in step b2), to an encapsulation operation with an aqueous polyethylene glycol solution as a continuous phase to provide micro- or nanoparticles having the active substance encapsulated therein. Sustained release particles obtainable thereby.
Patent IL-145345-A0 (IL)
Title: Diagnosis of lysosomal storage disorders using saposins and other markers
IPC: G01N33/577
Filed: 2000-03-17
Abstract: The invention provides methods of diagnosing or monitoring lysosomal storage disorders based on detecting levels of saposins, LAMPs and/or  alpha -glucosidase in patient sample. Elevated levels of saposins and/or LAMPs are indicative of a disorder. Elevated levels of  alpha  glucosidase are indicative of some types of lysosomal storage disorders and decreased levels of  alpha  glucosidase are indicative of other types of lysosomal storage disorder. In some methods, the profile of elevation of different saposins, LAMPs and  alpha  glucosidase allows distinction between different types of lysosomal storage disorder.
Patent IL-149204-A0 (IL)
Title: Microbiological method for producing aromatic aldehydes and/or carboxylic acids
IPC: C12N15/09
Filed: 2000-10-26
Abstract: Production of aromatic aldehyde or carboxylic acid (I) by culturing a microorganism that expresses xylene mono-oxygenase (XMO) or alkane mono-oxygenase (AMO) in a medium containing an aromatic substrate (II). Production of aromatic aldehyde or carboxylic acid of formula (I) by culturing a microorganism that expresses xylene mono-oxygenase (XMO) or alkane mono-oxygenase (AMO) in a medium containing an aromatic substrate of formula (II). [Image] Ar : monocyclic aromatic ring, optionally with one or more substituents; R 1>formyl or carboxy; n : 0-15; R 2>vinyl or (CH 2) m-R 3>, also where R 1>= carboxy, R 2>may be (CH 2) n-CHO; m : n+1; and R 3>hydrogen or hydroxy. Independent claims are also included for the following: (a) recombinant microorganism harboring an expression vector that contains, under control of the alk-regulatory system of Pseudomonas oleovoransGpol, the XMO-encoding genes xylM and xylA, or the AMO-encoding genes alkB, alkG and alkT; and (b) expression construct containing the genes specified in (a), operably linked to the alk-regulatory system.
Patent IL-150015-A0 (IL)
Title: Cutting insert and milling cutter
IPC: B23C5/10
Filed: 2002-06-04
Abstract: A milling cutter has a cutter body having insert pockets, with cutting inserts seated in the insert pockets. Each insert pocket has adjacent side and rear walls generally transverse to a base, the side wall being provided with two spaced apart generally flat and non-coplanar side support surfaces. Each cutting insert has a pair of opposing major side surfaces including two spaced apart generally flat and non-coplanar abutment surfaces. Upper edges of the side support surfaces abut the abutment surfaces.
Patent IL-154039-A0 (IL)
Title: Ventilated slatted roofing device
IPC: E04D13/03
Filed: 2001-07-18
Abstract: A slatted roofing device, includes a frame (1) receiving a lower series (2) of grid-type mounted slats and at least a support (3) superimposed on the frame (1) receiving an upper series (4) of grid-type mounted slats, the support (3) being transversely mobile with respect to the longitudinal direction of the slats on the frame (1) to modify the lateral position of the slats of the upper series (4) relative to those of the lower series (2), the slats shifting from a completely overlapping position when the roof is open to a partial overlapping position when the roof is closed. The device includes an apparatus for lifting the support (3) relative to the frame (1) to allow air to pass through the roof even when the series of upper (4) and lower slats cover the whole roof surface.
Patent IL-200323-A0 (IL)
Title: Synthesis of glyt-1 inhibitors
Filed: 2009-08-10
Abstract: The present invention relates to a process for preparation of a compound of formula I wherein Het, R1, R2, R3, and n are as defined herein and pharmaceutically acceptable acid addition salts thereof, which comprises reacting a compound of formula 21 with a compound of formula 8 to obtain a compound of formula 11 and coupling the compound of formula 11 in the presence of a coupling reagent or the corresponding acid halogenide with a compound of formula 15 to obtain a compound of formula I.
Patent IL-201040-A0 (IL)
Title: Battery connection device
IPC: H01M50/503
Filed: 2009-09-17
Abstract: The invention discloses a battery connection device, which includes a connection block that, made of insulating material, is positioned at an electrode end of a battery; the connection block is provided at both ends with a series connection mechanism, respectively, and at all sides with a parallel connection mechanism, respectively; the series connection mechanism is provided inside with a conductive slice electrically connected with the electrode end of the battery; the conductive slice is further led out to a fitting face of the parallel connection mechanism; and thus the conductive slices on the two connection blocks are electrically connected when the two batteries are parallel which are respectively provided with the connection block. The invention can make each unit battery connected modularly in series or parallel like a building block; the battery set obtained from this connection does not further need electrode connection by welding or battery fixing by assembling, which is convenient for operation as well as safe and reliable.
Patent RO-130938-A0 (RO)
Title: Method and intelligent system for on-line measuring and monitoring, in real time, the electric power produced/transported/distributed/delivered/consumed and the quality thereof
Inventor: MOLDOVEANU CONSTANTIN
IPC: G06F17/40
Filed: 2015-06-17
Abstract: The invention relates to a method and an intelligent system for on-line measuring and monitoring, in real time, the parameters of electric power produced, transported, distributed, delivered and consumed and the quality parameters of electric power, in order to allow the consumers to take quick and effective decisions. According to the invention, the method consists in acquiring the shape of current and voltage waves, in any measuring point, on one phase or on the three phases of an electric network, by sampling at various preset speeds, storing the same in the system memory, measuring and determining all the parameters that characterize the electric power consumption and quality, automatically identifying faults which may be voltage sags/surges at industrial frequency, voltage breakdowns, while ensuring the real-time transmission of the data measured to a management center, secure bidirectional communications with the management center and with the end consumers, implementation of a software module with electric power pricing function, detection, recording and warning in case of unauthorized access attempts. The system, as claimed by the invention, comprises some input amplifiers (1, 2, 3, 4, 5, 6, 7 and 8), of which three amplifiers are meant for the voltage on the three phases, three amplifiers are meant for the current on the three phases, one amplifier is meant for null current and one for null voltage, a data acquisition synchronization module (9) consisting of a PLL, a data acquisition module (10) consisting of an ADC stage (10) and an acquisition controller (13) which controls the ADC stage with the signals received from the PLL, an internal communication module, a computing and result storing, displaying and external transmission module (16) and a GPS module (17) for measurement synchronization.
Patent MC-2479-A1 (MC)
Inventor: STRINGA LUIGI
IPC: B41F33/14
Filed: 1998-09-07
Abstract: The model for the symbol is captured by an electronic camera from a printed image that is considered acceptable, and the image stored to produce a reference image. The image is then divided into multiple sub-images by superposing a fine grid. During inspection the distance from nodes (K1-K5) of the grid is measured (K'1-K'5), and the reference model adapted to correspond to these measurements.
Patent LU-46410-A1 (LU)
IPC: A61K35/74
Filed: 1964-06-27
Abstract: Cosmetic or therapeutic preparations in the form of powders containing microorganism metabolic products are prepared by stirring a conventional inorganic or organic cosmetic or therapeutic powder base with a fermentation broth, which contains the desired active ingredient(s) and which is free from solids, to form a pulp which is then spread to obtain as large a surface area as possible and is maintained at 20-25 DEG C. for 5-15 days in an atmosphere having a relative humidity of 80-100%, before being dried and ground.  The powder base may be an urea-formaldehyde resin, talcum, or levelite (which is silica having a particle size of 0.003m ).  The fermentation broth may be that described in Specification No. 984,897 or No. 1,008,281.  The powder obtained in the Example by treating silica with fermentation broth according to Specification No. 984,897, is stated to be highly active against inflammatory conditions in the mouth, skin eczema, mycosis, and unpleasant odours, especially odours of the body.
Patent LU-85141-A1 (LU)
Inventor: ALAIN LEGROS
IPC: C12P5/02
Filed: 1983-12-15
Abstract: 1. Process for the biomethanization of solid or semi-solid organic substrates, in which such a substrate suspended in water is subjected to the action of communities of microorganisms, having the effect of successively extracting water soluble products from the substrate, converting these solubilized products into acids and/or alcohols and methanizing these acids and/or alcohols in two fermentors mounted in series, characterised in that the suspension of organic substrate introduced into the first fermentor (1) is subjected to a solubilization of the organic substances contained therein, to an acidogenesis and to a methanization while the pH is maintained at 6.5 to 8.5, in that a liquid effluent deprived of solid substances and containing the excess of non-methanized acids and/or alcohols is withdrawn from the first fermentor (1) and this liquid effluent is transferred to the second fermentor (2) which is charged with methanogenic microorganisms, in which second fermentor this effluent liquid is methanized, also at a pH of 6.5 to 8.5, in contact with the methanogenic microorganisms, and in that a neutral or alkaline effluent liquid charged with methanogenic microorganisms is withdrawn from the second fermentor (2), and this effluent neutral or alkaline liquid is recycled to the first fermentor, optionally discontinuously.
Patent MA-24983-A1 (MA)
Title: Circuit adaptateur d'interface entre le reseau commute et le reseau via satellite (vsat).
Inventor: GIL ROSADO JOSE ANGEL
IPC: H04M3/00
Filed: 1999-09-23
Abstract: CIRCUIT ADAPTEUR D'INTERFACE ENTRE LE RÉSEAU COMMUTÉ  ET LE RÉSEAU VIA SATELLITE (VSAT) CONSISTANT EN UN ENSEMBLE DE BLOCS CONFIGURÉS COMME BLOCS D'INTERFACE D'ENTRÉE ET FONCTIONNANT COMME UN AMPLIFICATEUR D'ENTRÉE DIFFÉRENTIELLE ET DE DÉCOUPLAGE DE COURANT CONTINU, DE CONTRôLE AUTOMATIQUE DE GAIN ASSURANT LES SIGNAUX  ANALOGIQUES PROVENANT DU RÉSEAU PUBLIC COMMUTÉ, DE FILTRE DÉTECTEUR DE TONS, FONCTIONNANT COMME FILTRE PASSAGE BANDE, DE RECTIFICATEUR RECTIFIANT LES SIGNAUX  ANALOGIQUES, DE COMPARATEUR  FOURNISSANT à SA SORTIE UN SIGNAL NUMÉRIQUE CARRÉ DE LA MeME CADENCE, DE COMPTEUR TEMPORISATEUR COMPTANT DES PULSATIONS à CADENCE DÉTERMINÉE ET DE LOGIQUE DE CONTRôLE QUI DISCRIMINE LES ACTIONS à PRENDRE SUR LE RÉSEAU VIA SATELLITE  ( VSAT ) ET SUR LE RÉSEAU COMMUTÉ.
Patent MA-37391-A1 (MA)
Title: Forme cristalline d'un sel de succinate
Inventor: TUFILLI NICOLA
IPC: C07D471/10
Filed: 2013-03-15
Abstract: La présente invention concerne une nouvelle forme cristalline du sel de succinate du bloqueur du canal sodique épithélial (enac), ester dipropylcarbamoylméthylique de l'acide 3-(3-{2-[(e)-3,5-diamino-6-chloro-pyrazine-2-carbonylimino]-1,3,8-triaza-spiro[4.5]
Patent MA-41522-A1 (MA)
Title: Nouveaux peptides et nouvelle combinaison de peptides à utiliser dans l'immunothérapie du cancer de l'œsophage et d'autres cancers
Inventor: WEINSCHENK TONI
IPC: C07K14/635
Filed: 2016-07-05
Abstract: La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules à utiliser dans des procédés immunothérapeutiques. La présente invention porte en particulier sur l'immunothérapie du cancer. La présente invention a également trait à des épitopes peptidiques de lymphocytes t associés à une tumeur, seuls ou combinés à d'autres peptides associés à une tumeur, qui peuvent par exemple servir en tant que principes actifs pharmaceutiques de compositions vaccinales qui stimulent des réponses immunitaires antitumorales, ou stimuler des lymphocytes t ex vivo afin de les transférer ensuite dans des patients. Des peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou des peptides en tant que tels, peuvent également être les cibles d'anticorps, de récepteurs de lymphocytes t solubles et d'autres molécules de liaison.
Patent MA-42025-A1 (MA)
Title: Formule à base d´endo-polysaccharides et exo-polysaccharides de cyanobactéries pour le contrôle des phytosanitaire
Inventor: WAHBY IMANE
IPC: A01P3/00
Filed: 2018-02-16
Abstract: L'invention concerne une formule à base d´extraits de cyanobactéries pour stimuler les défenses des plantes contre les champignons phytopathogènes et les plantes parasites. La formule est développée à partir de biomasse et son milieu de culture de cyanobactéries contenant la spiruline. C´est un traitement préventif bio qui peut être appliqué à différents stades de culture, avant l´attaque par le phytopathogène et induire la défense naturelle des plantes traitées. La formule est un cyano-vaccin et contient la fraction polysaccharidique combinée issue de la biomasse et son milieu de culture et/ou des oligosaccharides et/ou des substances ayant un effet sur la défense de la plante et/ou des substances permettant sa stabilisation, conservation et application.
Patent UY-28903-A1 (UY)
Title: Nuevos derivados de piridazinona
Inventor: SWEN DR HOELDER
IPC: C07D401/14
Filed: 2005-05-17
Abstract: La presente invención se refiere a compuestos según la fórmula general (I), especificándose las definiciones de los sustituyentes X, R1 y R2 en la Memoria Descriptiva, así como a sus sales fisiológicamente aceptables, a métodos para producir estos compuestos, y a su uso como productos farmacéuticos. Estos compuestos son inhibidores de cinasa, en particular inhibidores de la cinasa CDK2 (cinasa 2 dependiente de ciclina).
Patent UY-30285-A1 (UY)
Title: Derivados de aminometilpirina, su preparacion y su aplicacion en terapéutica
Inventor: FRANCIS BARTH
IPC: A61P25/00
Filed: 2007-04-13
Abstract: Derivados de la aminometilpiridina que responden a la formula (I) en la que: Z; X; R1 y R2; R3 y R6; R4; R5; Ar1 y Ar2; n; Alk representan grupos químicos sustituyentes especificados en la descripcion del invento, y que se presentan también en forma de base o de sal de adicion, así como en forma de hidrato o de solvato. Se describen los métodos de prepracion y su aplicacion en terapéutica, particularmente destinados al tratamiento y prevencion de las enfermedades en las que están implicados los receptores de los cannabinoides CB1
Patent ES-156542-A1 (ES)
Title: Procedimiento de fabricacion de papel continuo estriado
Filed: 1943-02-05
Abstract: Nuevo procedimiento para la fabricación de papel continuo estriado caracterizado en preparar piezas de papel de cualquier clase y tamaño debidamente engomadas o con pegamento al que se le adicionan tiras de papel en sentido vertical u horizontal así como cruzadas sobre la parte engomada o pegajosa.
Patent ES-178424-A1 (ES)
Title: PERFECCIONAMIENTOS EN MáQUINAS DE LAVAR
Filed: 1947-06-13
Abstract: Perfeccionamientos en máquinas de lavar que incluyen una máquina del tipo que tiene una tina para recibir el líquido de lavado y un receptáculo tal como un cilindro para la admisión de las prendas a lavar y rotativamente montado en dicha tina y además medios para accionar dicho cilindro en una sucesión de operaciones máquina que comprende medios de transmisión accionados por un motor medios de velocidad reducida tal como un mecanismo de engrana que coopera con dichos medios de transmisión para hacer girar el receptáculo varias revoluciones primero en un sentido y luego en el opuesto para lavar las prendas; medios de velocidad elevada que cooperan con dichos medios de transmisión para hacer girar el receptáculo de velocidad elevada en un sentido. para secar las prendas centrífugamente y medios de control para hacer que los medios de velocidad reducida y los medios de velocidad elevada funcionen sucesivamente.