baber/WOPTO huggingface dataset:
Patent JP-2003198233-A (JP)
Title: Control method for array antenna
Inventor: TEI TAKASHI
IPC: H01Q9/30
Filed: 2001-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To lean to improve performance by each repetition of search, without needing a long learning sequence signal, as compared with the conventional ones.  <P>SOLUTION: A method includes steps where an adaptive control type controller 20 randomly perturbs a bias voltage vector V (n), using a bias voltage value V<SB>m</SB>as one component from a specified initial value by means of a random vector R (n) generated by a random number generator, an objective function value J (n) which is an cross correlation coefficient for the bias voltage vector V (n) before perturbation is compared with an objective function value J (n+1), being a cross-correlation coefficient for the bias voltage vector V (n+1) after perturbation; a bias voltage value V<SB>m</SB>corresponding to the increase of the cross- correction coefficient before and after perturbation is selected and set and then the vector V (n) is randomly perturbed and set from the selected bias voltage of each of variable capacitance diodes 12-1 to 12-6; and this setting is repeated.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003195637-A (JP)
Title: Developing device and image forming apparatus
Inventor: NAKASE TAKAHIRO
IPC: G03G21/00
Filed: 2001-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To stably obtain the image of a high quality by obtaining a desired image quality and desired density even in the case of developing operation in which the consumption of developer at each developing roller is large.  <P>SOLUTION: In the case of nearly simultaneously detecting that the amount of the developer (t) is less than a specified amount both at the inside of a first storing part 2a and at the inside of a second storing part 2b by respective developer amount detecting sensors 5a and 5b, the developer (t) is fed to the inside of the second storing part 2b by rotating a magnet roller 7 in the direction of an arrow B at first, and then, the developer (t) is fed to the inside of the first storing part 2a by rotating the magnet roller 7 in the direction of an arrow A, and the occurrence of the insufficiency of the developer at the developing roller 3b on a downstream side strongly affecting the sharpness of a developer image or the like is suppressed, so that the image of the high quality is obtained by preventing the occurrence of defective developing.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003195086-A (JP)
Title: Optical device connecting method and optical equipment
Inventor: MIYATA HIDEYUKI
IPC: G02B6/024
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide an optical device connecting method and an optical equipment that can suppress periodic wavelength-dependent loss or the like due to the inter-polarization-mode interference generating in connecting a plurality of optical devices using a polarization maintaining optical fiber line.  <P>SOLUTION: In this optical device connecting method, a plurality of optical devices 11, 12 are connected to each other by means of a polarization maintaining optical fiber line 2<SB>12</SB>having the optical characteristic in which light propagates in nearly the same distance along two different axes of polarization. As a result, the periodic wavelength-dependent loss and the like generating by the inter-polarization-mode interference of the optical fiber line 2<SB>12</SB>can be offset and suppressed, even if the polarizing direction of the input/output light in each optical device 11, 12 is not fully coincident with the direction of the axis of polarization of the optical fiber line 2<SB>12</SB>.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003203361-A (JP)
Title: Information storage device and method for retracting head thereof
Inventor: IUMI YOSHIAKI
IPC: G11B7/121
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide information recording and/or reproducing equipment for moving a head with respect to a recording medium to perform recording and/or reproduction, a head retracting method, information recording and/or reproducing equipment capable of surely retracting the head from the recording medium about a head retraction circuit, a head retracting method and the head retraction circuit.  <P>SOLUTION: This information recording and/or reproducing equipment comprises the head disposed opposite to the recording medium for recording and/or reproducing information on/from the recording medium, a moving means for moving the head, a capacitor charged by a power supply, and a retracting means for driving the moving means by electric charge stored in the capacitor in accordance with the voltage of the power supply to retract the head.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003203627-A (JP)
Title: Manufacturing method and device of hydrogen storage alloy particles
Inventor: KANEKO JUN
IPC: H01M4/38
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a manufacturing method and device of hydrogen storage alloy particles which can generate hydrogen storage alloy particles without accuracy, easily and in a simple structure.  <P>SOLUTION: A high-pressure water jet stream 18 is blown off vertically through the inside of a liquid supply space 14A of a nozzle 14, and at the same time, hydrogen storage alloy liquid 20 is supplied into the liquid supply space 14A at a given flow rate and made contacted with the high-pressure water jet stream 18 from its surroundings to be crushed and cooled to generate hydrogen storage alloy particles 21.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003196008-A (JP)
Title: Input device and information input system
Inventor: MORIYA TAKEKI
IPC: G06F3/041
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To make a sheet on which projections are formed, out of a material excluding a transparent material, and to prevent input keys and parts corresponding to the input keys from being damaged even in continuous input.  <P>SOLUTION: This input device is composed of a printed board 1 on which various elements such as a transistors and the like are formed, a dome sheet 31 positioned on the printed board 1 and having projecting parts 31a, a liquid crystal display 21 positioned on the dome sheet 31 for displaying an image, and a touch panel 11 positioned on the liquid crystal display 21, detecting a position touched by a finger or a pen, and outputting a signal indicating the same. A casing 2 accommodating the printed board 1 and the like is provided with a key 3 for inputting the instruction different from the instruction inputted from the touch panel 11, and a speaker 4 generating the voice and the like for encouraging the input and instruction by a user.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003501173-A (JP)
Title: スリーディンプルタイプのゴルフボール
IPC: A63B37/00
Filed: 2000-06-05
Abstract: (57)【要約】
本願発明は外面にアレンジされた３種で成る複数のディンプル（２００、２０２、２０４）を有したゴルフボール（５）を提供する。各ディンプルの半径は異なる値を有している。ディンプル（２００、２０２、２０４）は菱形１２面体に従ってボール表面にアレンジされている。
Patent JP-2003513007-A (JP)
IPC: A23L33/00
Filed: 2000-06-23
Abstract: Methods, compositions and articles for blocking transepithelial transmission of HIV with ICAM-1 angonist/antagonists are provided. The ICAM-1 agonist/antagonists block viral transmission at the site of exposure to the virus. Blocking viral transmission does not require blocking the binding of ICAM-1 to LFA-1. The ICAM-1 agonist/antagonists may be applied to mucosal surfaces, on or in contraceptive devices or in oral solutions such as breast milk supplements and infant formula.
Patent JP-2003503161-A (JP)
IPC: A61K9/10
Filed: 2000-06-30
Abstract: The constituents of the acid dialysis concentrate required for producing dialysis fluid are not - as is the case in the prior art - provided as a dry concentrate or as a true solution, but are provided as a suspension of undissolved substances  preferably sodium chloride and, optionally, other substances - in an aqueous solution of the remaining constituents. The suspension is introduced into a container designated as an acid cartridge, is stored, transported and is then used. A liquid concentrate is produced from the suspension at the location of dialysis by means of a device and is processed into a dialysis fluid by using existing dosing and safety systems of conventional dialysis units. The inventive system makes it possible to realize savings and advantages with regard to transport, storage and handling without lowering the common standard for patient safety which is applied to the use of conventional liquid concentrate.
Patent JP-2003504294-A (JP)
IPC: C04B103/40
Filed: 2000-07-04
Abstract: A cementitious formulation comprising a cement and an oligomeric dispersant is provided. The dispersant is a reaction product of two or three moieties. The first moiety (A) is a nonpolymeric, functional moiety that adsorbs onto a particle, and wherein one or more A moieties together contain at least two residues to provide attachment of the dispersant onto a particle to be dispersed. The second required moiety (C) is a linear or branched water soluble, nonionic polymer that provides the dispersing capability. A third moiety (B), if present, is a nonpolymeric moiety disposed between the first and second moiety, to connect the first and second moieties. A method is provided for dispersing a cementitious formulation comprising a cement in water, including providing in said cementitious formulation the above oligomeric dispersant. A combination of any cement dispersant with an oligomeric dispersant wherein at least one A moiety is blocked is also provided in a cementitious formulation and in a method of making such cementitious formulation.
Patent JP-2003506938-A (JP)
Title: ウェアラブルパーソナル通信装置
IPC: H01Q11/08
Filed: 2000-07-19
Abstract: (57)【要約】
手首に付けられるワイヤレス電話機のようなウェアラブルパーソナル通信におけるアンテナはヘリカルアンテナ又は他の物理的に短くされた電気アンテナである。このようなアンテナは、人体の近くにあり、人体に対し垂直であり高められる電界の成分を使用することによって広い向きの範囲で良好な性能を有する。１つの実施例では、マイクロホンはアンテナの上部に配置される。マイクロホンはアンテナに対し頂部負荷として作用することが可能であり、それにより短いアンテナを使用することが可能となる。アンテナは同軸ケーブルから形成され、マイクロホンと装置の本体内の受信器回路との間に電気的接続を与えることを可能にする。無線周波数で低いインピーダンスを有するようマイクロホンを配置することによって、同軸ケーブルは誘導スタブとして作用しアンテナを更に短くすることが可能となる。
Patent JP-2003531454-A (JP)
IPC: H01R4/50
Filed: 2000-08-02
Abstract: A no-crimp electrical connector which does not require any metal pieces and is essentially comprised of two molded plastic body members. A molded plastic first body member has a connection chamber and a threaded wall bounds the connection chamber. A second molded plastic second body member has an externally threaded surface threadably engageable with the threaded wall in the first body member. One of the body members has an integral central conically shaped element which has an axis coaxial with the body member in which it is formed. The second body member has a throughbore with the throughbore having first and second ends. The first throughbore end is shaped to accommodate two or more wires in parallel, side-by-side relation. Preferably, the shape is oval or oblong. The second end of the throughbore has conical walls which are complementary to the conical shape of the integral central conical element so that the wire ends of the two or more wires are clamped together between the integral central conical shaped element and the conical surface when the threadably engaged surfaces are rotated relative to each other to move the integral central conical shaped element and the conical surfaces towards each other, respectively.
Patent JP-2003507158-A (JP)
IPC: B01F23/30
Filed: 2000-08-10
Abstract: Leaching of solid matter from a sludge uses a tubular reactor which is equipped with a concentric central pipe and a double-action mixer. The mixer is located in the vicinity of the central pipe's lower edge. Leaching solid matter from a sludge with the aid of an oxygen-containing gas uses a tubular reactor. The reactor is equipped with a concentric central pipe (2), and a double-action mixer (5) in the vicinity of central pipe's lower edge (7). With the aid of the mixer, the sludge flows downward in the central pipe, and then turns upward outside the central pipe as the gas is fed at the same time into the sludge and dispersed into small bubbles. The mixer preferably has nearly rectangular straight lower blades which facilitate the dispersion of the gas and the turning of the discharge sludge into the upward flow. It has curved upper blades which facilitate the downward flow of the sludge in the central pipe. It is preferred that the cross-section area remaining between the mixer and the central pipe is adjusted to be less than half (preferably at most one third) of the flow cross-section area in the central pipe and the lower edge of the central pipe is at a height (measured form the reactor bottom) of 0.7-1.3 times that of the reactor diameter, preferably the same as the diameter. The cross-section ratio of the central pipe and its surrounding reactor casing is preferably below 0.1.
Patent JP-2004500792-A (JP)
IPC: B60L50/16
Filed: 2000-08-03
Abstract: A continuously variable electromagnetic transmission comprising a collector-less, axial-flow dynamo electric machine (3) provided with an input shaft (2) and an output shaft (4), and means (20) for controlling and supplying electricity at variable frequencies to said machine. The dynamo electric machine comprises a stator (16), a first rotor (12) which is connected to the input shaft, and a second rotor (15) which is connected to the output shaft and embodied in such a way that  it can interact with the first rotor and the stator, whereby the two rotors and the stator are formed by discoid elements. The inventive transmission comprises means for axially displacing at least one of the discoid elements in order to modify the width of the axial gap between said element and an adjacent discoid element, whereby the magnetic field can be regulated by variations in said gap and the two rotors can be mechanically coupled to each other. Said transmission can be used in a motor vehicle, especially a motor vehicle with hybrid propulsion.
Patent JP-2003508225-A (JP)
IPC: B21D17/02
Filed: 2000-08-23
Abstract: The invention relates to a device for creating a recess in a workpiece which has a tool (30) which can be moved forward by a forward feed device (31) in a tool (30) which can be moved forward and which has at least one machining element (35; 35a-35d) for the production of a recess (2a-2d) in said workpiece (3a-3e). According to the invention, the tool (30) has at least one machining element (35; 35a-35d) with a machining area (40) which is wedge-shaped and which projects from a front end (38) to an opposite end (39) of the machining area (40) and widens to a breadth (b) thereby substantially corresponding to the axial elongation (I) of the recess to be produced (2a-2d), rising from the base (36) of the tool (30) to a height (h) and having at least the depth (t) of the recess (2a-2d) to be produced. Said device (1) has an apparatus (10, 11; 20, 21) which can move the tool (30) in a processing direction (B) at various machining forces.
Patent JP-2003510201-A (JP)
IPC: C09D183/04
Filed: 2000-09-11
Abstract: Mold-release agent for producing thermoset moldings with a hydrophobicized surface, where the agent comproses (I) at least one compound with mold-release action, and also (ii) at least one reactive, where appropriate hydrolyzable, silane compound, which is capable of reacting chemically in situ with the thermoset surface which forms during the molding process. The use of a mold-release agent of this type in a molding process and/or in a post-curing process for the production of thermoset moldings with a hydrophobicized surface, and also the moldings produced in this way.
Patent JP-2003510724-A (JP)
Title: パーセプション管理用ポジショニングシステム
IPC: G06Q30/02
Filed: 2000-09-28
Abstract: (57)【要約】
パーセプション管理用コンピュータ実装ポジショニングシステムのための方法、装置、および製品。ひとつ以上のプロセッサを有するコンピュータシステム上で、パーセプション管理が、データベースに記憶される複数の視覚表現を用いて行われる。一つ以上のプロセッサと前記データベースはコンピュータシステムに結合されている。表現は、ひとつ以上の特定視覚表現、並びに、ひとつ以上の他の視覚表現を含み、各視覚表現はキューを具体化し、人が見ると直ちに、これら関連キューが、所望のパーセプションを相乗的にトリガすることにより人の行動に影響を及ぼすシグナルを送る。パーセプション管理は、コンピュータシステムからユーザへ、コンピュータシステムに結合された出力装置上にひとつ以上の特定視覚表現を出力することによって実行される。出力されたひとつ以上の特定視覚表現に対する分類情報は、コンピュータシステム内のひとつ以上のプロセッサに結合される入力装置を用いて、ユーザから受け取られる。出力されたひとつ以上の特定視覚表現に対する、ユーザから受け取った分類情報は、データベースに記憶される。そして、出力されたひとつ以上の特定視覚表現に対する受け取られた分類情報と、ひとつ以上の他の視覚表現に対する分類情報とを、データベースへのアクセスを介して相互参照することによって、複数の視覚表現のうちのひとつ以上の視覚表現に対する受け取られた分類情報が、人の行動に影響を及ぼす関連キューを識別するために取り出される。
Patent JP-2003511168-A (JP)
Title: 消防設備、スプレイヘッド
IPC: B05B1/20
Filed: 2000-10-06
Abstract: (57)【要約】
本発明は、消防用設備であって、所定数のスプレイヘッド（３３０ａ、３８０ａ）、スプレイヘッドに消火用媒体を導くためのパイプシステム（３８１）を備え、スプレイヘッドが、到来する消火用媒体のための入口を有するホルダー本体、少なくも１個のノズル、及び設備が非作動モードにありかつ設備の作動の際に係合の解放により解放位置に変位可能であるように配列され前記ノズルの前面の保護位置に係合されたカバーを備え、この解放位置においては、スプレイヘッドが作動位置にあるときにノズルが消火用媒体をスプレイするようにカバーが前記ノズルを邪魔しない消防用設備に関する。設備を塵埃及び不純物に強く暴露される可能性のある条件下で使用し得るため、及び設備のスプレイヘッドが衝撃又は火災によらない熱に暴露されることにより作動しないようにするために、この設備は、スプレイヘッド（３３０ａ、３８０ａ）が、流体圧力の効果によりホルダー本体に関して変位され、これによりカバーを解放するように係合に力を加える変位可能な装置を備えることを特徴とする。
Patent JP-2003515119-A (JP)
IPC: G01N24/10
Filed: 2000-11-15
Abstract: A simplified magnetic resonance flowmeter and flow measuring method, based on the dwell time of spins in the H1 Larmor radio frequency nutation field, which employs periodic H0 field gradients to phase modulate the spins so as to measure mean velocity of flow in near uniform velocity profiles or to map velocity of flow in non-uniform velocity profiles, which does not require pulse techniques and is relatively independent of relaxation and diffusion parameters consisting of a magnetizing section of pipe with a strong H0 magnetic field with a receiving section with orthogonal periodic phase modulating gradient coils, H1 Larmor radio frequency excitation (nutation) coils, and sideband receiver coils; utilizing a demodulating and cross-correlating receiver and a control system that permits concordant analysis of composition.
Patent JP-2003515474-A (JP)
Title: 異種タイヤの同時製造用プラント
IPC: B29D30/08
Filed: 2000-11-21
Abstract: (57)【要約】
種類の異なるタイヤを製造するプラントであって、各々が少なくとも１種類の被処理タイヤに少なくとも１つの構成部材を組付けるように設計されている複数のワークステーション（５，６，７，８，９，１０）を有する複合製造装置（２）と、製造される各種タイヤ用の加硫金型（２４，２５，２６，２７，２８，２９）を有する複合加硫装置（３）と、ワークステーション（５，６，７，８，９，１０）と複合加硫装置（３）との間で動作する、被処理タイヤの機能的移送および移動用装置と、前記ワークステーションと関連付けられた保持ステーション（２２，２３，２４，２５，２６）とを備え、保持ステーション、金型、および機能的移送および移動用装置の数が、製造する種類毎のタイヤの数に相当するタイヤの組が得られるように、相互に関して選択されている。
Patent JP-2003532948-A (JP)
Title: リソースドメイン間で通信するための装置および方法
IPC: G06F9/44
Filed: 2000-11-29
Abstract: (57)【要約】
【解決手段】  リモートメソッドを実行するための方法が開示されている（２００）。リモートメソッドの各引数は、リモートオブジェクトである場合（例えば、引数の宣言されたクラスが、リモートマーカインタフェースを実装する場合）にはラップされる（２０２）。しかしながら、リモートメソッドの各引数は、リモートオブジェクトではない場合にはコピーされる（２０２）。リモートメソッドは、ラップもしくはコピーされた引数を用いて呼び出される（例えば、ラップもしくはコピーされた引数は、呼び出されたメソッドに受け渡される）（２１０）。次いで、呼び出されたリモートメソッドの結果は、リモートオブジェクトである場合（例えば、その結果の宣言されたクラスがリモートマーカインタフェースを実装しない場合）にはラップされる（例えば、結果を受け取るプロセスに受け渡される前に）（２１６）。逆に、リモートオブジェクトでない場合には、リモートメソッドの結果は、コピーされる（例えば、結果を受け取るプロセスに受け渡される前に）（２１６）。
Patent JP-2003516862-A (JP)
Title: 圧縮ハイドロフォーミング
IPC: B21D51/16
Filed: 2000-12-15
Abstract: (57)【要約】
【課題】圧縮ハイドロフォーミング
【解決手段】被加工素材(１９)の内部に液圧(２１)を付与し、加圧された被加工素材(１９)をダイキャビティ(１８)を有するダイ(１１，１２)内で包囲することによって、チューブ状の被加工素材(１９)を成形する。ダイキャビティ(１８)の一部または全部は、その被加工素材(１９)の外側周辺部よりも小さい内側周辺部を有する。これが、被加工素材(１９)に圧縮成形を施す。
Patent JP-2003518070-A (JP)
Title: 皮膚の病原菌フローラに対する抗付着性薬剤
IPC: A61K35/747
Filed: 2000-12-13
Abstract: (57)【要約】
本発明は哺乳動物の皮膚生態系を安定化および／または調整する香粧用、医薬用または獣医用組成物の製造に対し細菌剤を使用することに関する。この細菌剤は皮膚細胞に対するその付着特性および皮膚系の病原菌に対する抗付着性に対し選択した細菌抽出物または細菌である。本発明はこの型の薬剤を含有する組成物にも関する。
Patent JP-2003517839-A (JP)
IPC: C12N1/19
Filed: 2000-12-22
Abstract: Nucleic acid constructs containing HIV-1  gag / pol  and SIV  gag  or SIV  env  genes which have been mutated to remove or reduce inhibitory/instability sequences are disclosed. Viral particles and host cells containing these constructs and/or viral particles are also disclosed. The exemplified constructs and viral particles of the invention may be useful in gene therapy for numerous disorders, including HIV infection, or as a vaccine for HIV-1 immunotherapy and immunoprophylaxis.
Patent JP-2003522424-A (JP)
Title: 研磨組成物
IPC: H01L21/321
Filed: 2001-02-02
Abstract: (57)【要約】
単一工程のＣＭＰ研磨、または２工程のＣＭＰ研磨のいずれかにより、絶縁層から金属を除去するための研磨組成物であって、それぞれのシラノールを含む分子を有する物質と、シラノールを可溶化させ、研磨中に絶縁層の水和表面に吸着する濃度のイオンとを含む水溶液を含む。
Patent JP-2004500082-A (JP)
Title: ニューロトリミン様ポリペプチドおよびポリヌクレオチドに関する方法と材料
IPC: A61K38/00
Filed: 2001-02-02
Abstract: 本発明は、新規性のあるヒトの分泌性ニューロトリミン様ポリペプチドに対応するポリヌクレオチドおよびそれらの突然変異体または変異体でコード化された、新規性のあるポリヌクレオチドおよびポリペプチドを提供するものである。こういうポリヌクレオチドは、ヒトの視床のｃＤＮＡライブラリから分離された核酸配列（Ｈｙｓｅｑクローン認識番号１０４６８５６２）で構成されている。本発明のその他の特徴には、新規性のあるヒトの分泌性ニューロトリミン様ポリペプチド、およびそのようなポリペプチドに特異的な抗体の生成プロセスに関係するベクターが含まれる。
Patent JP-2003523488-A (JP)
Title: 無線自動水位調節方法及びそのシステム
IPC: F04B49/00
Filed: 2001-02-16
Abstract: (57)【要約】
本発明は、無線自動水位調節方法及びそのシステムに関するもので、原水を取水するための取水井戸（２４）と、前記取水井戸（２４）内の原水をポンピングするためのポンピング手段（２２）と、前記ポンピング手段（２２）から取水された原水を供給するための送水管（３６）と、前記送水管（３６）内の水圧を感知するための圧力感知手段（３４）と、前記送水管（３６）内の原水の逆流を防止するための逆止め弁（３４）と、前記送水管（３６）を介して供給された原水を貯蔵するための貯蔵手段（３００）と、前記圧力感知手段（３４）から入力されたデータを加工して出力するためのドライブコントローラ（１１０）と、システムの各種状況を監視、制御及びディスプレイするためのメインコントローラ（１００）とを含んでなり、原水が存在する地点から所望の所定の貯蔵手段まで送水管を介して移送させるための距離が遠距離の場合に、送水管に取り付けられた圧力感知手段で水圧を感知して、自動に原水の貯蔵量を決定及び制御することにより、効率的な水位調節を可能にしたものである。
Patent JP-2003524733-A (JP)
Title: 高温ガス案内構成要素特にガスタービンの構造部分に対する熱遮蔽装置
IPC: F23M5/02
Filed: 2001-01-25
Abstract: (57)【要約】
本発明によれば、高温ガス室、例えばガスタービン設備の燃焼室（７）は熱遮蔽要素（１）で内張りされている。閉ループ式冷却系は、熱遮蔽要素（１）を中空体として形成しその中に冷却空気供給路を介して冷却空気が流れるようにすることによって構成される。冷却空気が熱遮蔽要素（１）から少なくとも１つの開口（８）を通して流出されると、その冷却空気はタイル張りされた中間室（５）に集められ、続いて燃焼プロセスのために利用される。
Patent JP-2003526376-A (JP)
IPC: C12N15/63
Filed: 2001-03-13
Abstract: The invention features a method of promoting an alteration at a selected site in a target DNA, e.g., in the chromosomal DNA of a cell. The method includes providing, at the site: (a) a double stranded DNA sequence which includes a selected DNA sequence; (b) an agent which enhances homologous recombination, e.g., a Rad52 protein or a functional fragment thereof; and (c) an agent which inhibits non-homologous end joining, e.g., an agent which inactivates Ku such as an anti-Ku antibody or a Ku-binding oligomer or polymer, and allowing the alteration to occur. The agent which inhibits non-homologous end joining, e.g., a Ku inactivating agent such as an anti-Ku antibody, is preferably provided locally. Components (a), (b), and (c) can be introduced together, which is preferred, or separately.
Patent JP-2003527868-A (JP)
IPC: A23G9/32
Filed: 2001-03-30
Abstract: A calcium and/or nutritional mineral fortified milk or milk powder product utilizes pyrophosphates or orthophosphates in combination with maintenance of pH within the range of 6.5 to 7.5 to render the milk heat stable. Additional calcium and/or nutritional mineral is added in soluble form either before or after the phosphate addition. The preferred orthophosphates are one or more of monosodium dihydrogen orthophosphate, disodium hydrogen orthophosphate, trisodium orthophosphate, monopotassium dihydrogen orthophosphate, dipotassium hydrogen orthophosphate and tri potassium orthophosphate. Addition of an alkaline agent to adjust the pH is not needed if an appropriate mix of orthophosphates is used. The milk products or milk products recombined from milk powders are heat stable and do not have the problems of translucency, gritty mouth feel or sedimentation which can be associated with other stabilized fortified milks.