baber/WOPTO huggingface dataset:
Patent WO-2020102303-A1 (WO)
Title: Use of disulfiram and other compounds to treat cancers with loss of chromosome 16q and/or low expression of metallothionein proteins
Inventor: CORSELLO STEVEN
IPC: A61K31/145
Filed: 2019-11-13
Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of cancers, particularly cancers that exhibit arm-level loss of chromosome 16q, focal copy loss of 16q13 and/or low expression of metallothionein proteins, such as certain uterine, ovarian, gastroesophageal and lung cancers. Three known drugs, disulfiram, elesclomol and thiram, as well as certain disulfiram metabolites, are specifically provided for killing cancer cells characterized by arm-level loss of chromosome 16q, focal copy loss of 16q13 and/or low expression of metallothioneins. The instant disclosure therefore provides for selecting and/or administering disulfiram, elesclomol and thiram and/or active metabolites or derivatives of disulfiram, elesclomol and thiram as a therapeutic agent(s) to target a cancer cell and/or subject having or at risk of developing a cancer. Methods and compositions for therapies that include such compounds are also provided.
Patent WO-2020102327-A1 (WO)
Inventor: HABEEB SHAIK KHADAR
IPC: G06Q20/00
Filed: 2019-11-13
Abstract: Provided is a system for predicting authorization of a payment transaction that includes at least one processor programmed or configured to receive electronic payment card data associated with an electronic payment card involved in a payment transaction, determine an authorization rate associated with an application of the electronic payment card based on the electronic payment card data associated with the electronic payment card, determine whether to communicate an authorization request message for the payment transaction based on the authorization rate associated with the application of the electronic payment card, communicate the authorization request message based on determining to communicate the authorization request, and determine to authorize the payment transaction based on an authorization response message. A computer program product and method are also disclosed.
Patent WO-2020102618-A1 (WO)
Title: Monothérapie anticancéreuse utilisant la sa-4-1bbl
Inventor: SHIRWAN HAVAL
IPC: A61K47/50
Filed: 2019-11-15
Abstract: La présente invention concerne des procédés de traitement et de prévention du cancer. En particulier, l'invention concerne des procédés utilisant la SA-4-1BBL en tant qu'agent de monothérapie pour traiter, prévenir ou réduire le risque de cancer, traiter, prévenir ou réduire le risque de tumorigenèse et traiter, prévenir ou réduire le risque de récidive tumorale post-chirurgicale. L'invention concerne également la SA-4-1BBL destinée à être utilisée en tant que monothérapie dans de tels procédés.
Patent WO-2020117800-A1 (WO)
Title: A method and system for removing contaminants from a gas stream using a liquid absorbent
Inventor: ZHENG Z FRANK
IPC: B01D53/78
Filed: 2019-12-03
Abstract: Embodiments described herein provide methods of operating a linear contactor for absorbing contaminants from a gas stream. The gas stream flows from a first end to a second end of the linear contactor. Fresh absorbent is provided at the first end of the linear contactor based on the theoretical minimum amount of absorbent needed to remove the contaminants. Absorbent is recycled from the second end to the first end of the linear contactor. Fresh absorbent is provided at the second end based on chemical condition of the recycled absorbent. Apparatus for practicing the method is also described.
Patent WO-2020131715-A1 (WO)
Inventor: ANANTH SHARATH
IPC: H01Q25/00
Filed: 2019-12-16
Abstract: The disclosure provides for a system for communication with a client device. The system includes a first transmitter (210a) configured to transmit a first signal ((301a) and a second transmitter (212b) configured to transmit a second signal (301b). The first signal is configured for a first communication band, and the second signal is configured for a second communication band different from the first communication band. The system also includes a hybrid coupler (304) configured to split the first or second signal to a first part and a second part. In addition, the system also includes a first antenna (306a) configured to transmit the first part, and a second antenna (306b) configured to transmit the second part. The second antenna is oriented perpendicularly relative to an orientation of the first antenna.
Patent WO-2020139688-A1 (WO)
Title: Tête de pompe pour pompe péristaltique
Inventor: WANG RUOYA
IPC: F04B53/16
Filed: 2019-12-19
Abstract: L'invention concerne des têtes de pompe pour ensembles pompes péristaltiques. Par exemple, une tête de pompe pour une pompe péristaltique comprend un lit d'occlusion, un guide de rotor, un ensemble rotor positionné entre le lit d'occlusion et le guide de rotor et un trajet pour le tube. Le trajet comprend une partie d'entrée, une partie de sortie et une partie de raccordement qui relie les parties d'entrée et de sortie. La partie d'entrée est définie entre le lit d'occlusion et le guide de rotor, la partie de sortie est définie entre le lit d'occlusion et le guide de rotor et la partie de raccordement est définie entre le lit d'occlusion et l'ensemble rotor. En outre, le lit d'occlusion est mobile par rapport au guide de rotor et à l'ensemble rotor. Dans des modes de réalisation donnés à titre d'exemple, la tête de pompe pousse un écoulement de fluide à travers le tube pour fournir un fluide de refroidissement à un ensemble sonde médicale pour administrer de l'énergie au corps d'un patient.
Patent WO-2020171887-A1 (WO)
Title: Stabilisateur d'échantillon de microsection
Inventor: GREEN DARRIN
IPC: G02B21/26
Filed: 2019-12-20
Abstract: L'invention concerne un stabilisateur d'échantillon de microsection pour aligner et stabiliser un échantillon de microsection (102) pour une inspection microscopique comprenant un cadre (120) comprenant une base (122) et au moins une partie de nivellement (126a, 126b) supportée par la base. La ou les partie(s) de nivellement peut/peuvent définir une fenêtre de visualisation (128) pour un microscope. Le stabilisateur d'échantillon de microsection comprend une région intérieure à l'intérieur du cadre, et au moins un dispositif conforme (132) utilisable à l'intérieur de la région intérieure du cadre et utilisable pour être supporté par la base. Le dispositif conforme reçoit et supporte l'échantillon de microsection, et polarise l'échantillon de microsection contre la ou les partie(s) de nivellement du cadre pour stabiliser l'échantillon de microsection, de telle sorte qu'une surface de plan d'examen de l'échantillon de microsection est alignée et visible à travers la fenêtre de visualisation par le microscope.
Patent WO-2020142486-A1 (WO)
Inventor: DEVITA ROBERT
IPC: C07D235/26
Filed: 2019-12-31
Abstract: Disclosed are kinase inhibitor compounds having the following structure: (I), or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where R 1 , R 2 , R 3 ,R 4 , R 5 , R 6 , N-Ar, X, Y, Z, and AA are as defined herein. Also disclosed are compositions containing the kinase inhibitor compounds, methods of inhibiting activity of a kinase in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.
Patent WO-2021071540-A1 (WO)
Title: Seven degree of freedom positioning device for robotic surgery
Inventor: KIM DANIEL H
IPC: A61B34/30
Filed: 2020-01-17
Abstract: An instrument cart configured to position an instrument controller at a desired location and attitude pitch with respect to an incision location of a patient includes a base, a lift member moveable with respect to the base, a first planar translation member connected to the lift member and arcuately moveable with respect thereto, a second planar translation member connected to the first planar translation member and arcuately moveable with respect thereto, a third planar translation member connected to the second planar translation member and arcuately moveable with respect thereto, an arcuate slide base connected to the third planar translation member and moveable with respect thereto and an arcuate slide coupled to the arcuate slide base, and moveable with respect thereto; and an instrument controller coupling connected to the arcuate slide member, the instrument controller connected thereto and movable with respect thereto.
Patent WO-2020163190-A1 (WO)
Title: Collecteur d'actionneur intégré pour ensemble de soupapes multiples
Inventor: KEEPER BRANDEN W
IPC: F16K27/02
Filed: 2020-02-03
Abstract: Un ensemble actionneur comprend un boîtier d'actionneur unitaire délimitant une pluralité de cavités d'actionneur s'étendant chacune le long d'un axe central depuis une surface supérieure du boîtier d'actionneur jusqu'à une surface inférieure du boîtier d'actionneur. Une pluralité d'éléments d'actionnement sont disposés chacun dans une partie de lamage supérieure d'une cavité correspondante parmi la pluralité de cavités d'actionneur et mobiles à l'intérieur de la cavité d'actionneur correspondante. Une pluralité d'arbres de sortie s'étendent chacun à travers un alésage inférieur dans une cavité correspondante parmi la pluralité de cavités d'actionneur, chaque arbre de sortie étant entraîné par un élément correspondant parmi la pluralité d'éléments d'actionnement.
Patent WO-2020163448-A1 (WO)
Inventor: BONIFANT CHALLICE L
IPC: A61K36/00
Filed: 2020-02-05
Abstract: The disclosure provides a chimeric antigen receptor (CAR) polypeptide having an antigen binding domain comprising an extracellular lectin which specifically binds to glycoproteins expressed on the surface of target cells. Also provided herein are engineered lymphocytes expressing the CAR polypeptide, a nucleic acid molecule encoding the CAR polypeptide, and methods of treating cancer.
Patent WO-2020176423-A1 (WO)
Title: Outils de nettoyage de surfaces
Inventor: MARTINEZ LORENA
IPC: B08B9/087
Filed: 2020-02-24
Abstract: L'invention concerne un outil de nettoyage de surfaces comprenant un cadre supportant un panneau élastiquement souple supporté par le cadre dans une configuration arquée de telle sorte qu'au moins une parmi les première et seconde parties d'extrémité opposées du panneau élastiquement souple peut être rapprochée de l'autre partie d'extrémité.
Patent WO-2020176493-A1 (WO)
Title: Systems and methods for a cable clip
Inventor: GOODFELLOW ANDREW C
IPC: H01R13/627
Filed: 2020-02-25
Abstract: Various embodiments of a cable clip having a clip housing configured to engage a casing to establish an operative connection with a portable device encased within the casing are disclosed.
Patent WO-2020176697-A1 (WO)
Title: Insect repelling compositions and methods of manufacture thereof
Inventor: EDERER G
IPC: A01N25/00
Filed: 2020-02-27
Abstract: Insect-repelling compositions comprise from about 0.001% to about 10% by weight of plant essential oils. The balance of the composition to 100% by weight includes deionized water, vanillin powder, isopropanol, glycerin, an emulsifier (such as polyglycerol oleate and/or sodium lauryl sulfate), and an aqueous chitosan formulation. The chitosan formulation comprises ≤8% volume of chitosan and ≤8% volume of acetic acid or vinegar.
Patent WO-2020190961-A1 (WO)
Inventor: SAMAKAR AMIR
IPC: A61F9/00
Filed: 2020-03-17
Abstract: Peristaltic micropump assembly configured to pump fluid from a patient and/or deliver pharmaceutical agents to the patient, wherein the micropump assembly includes: a rotor (136) configured to rotate about an axis and comprising a compressing member (134) configured to rotate along a circumference, and a fluid chamber (120) positioned at least partially around the circumference. The fluid chamber (120) includes a round outer ring (122) and a membrane (124) attached to the outer ring (122) and opposing an inner face of the outer ring (122). The compressing member (134) is configured to compress the fluid chamber (120) and move a fluid through the fluid chamber (120). The micropump assembly fits within a housing that is sized and shaped to be implanted in the patient. For example, the micropump assembly can be inserted into the patient's ocular cavity and configured to displace fluid from the patient's eye.
Patent WO-2020197869-A1 (WO)
Inventor: NIA NIMA
IPC: A61F2/24
Filed: 2020-03-18
Abstract: Described herein are artificial valves that have a frame and leaflets that grow or expand with a patient. Upon placing the valve inside the patient, the valve expands as the annulus of the patient expands. The frame of the valve is configured to expand which in turn causes the leaflets to expand (e.g., to grow). The valve includes a thin undulating wire embedded inside the leaflets. As the annulus of the patient grows, the frame expands, and as the frame expands, the leaflets grow. The growth or expansion of the leaflets is configured so that the valve continues to operate properly (e.g., the leaflets continue to coapt) with expansion of the annulus. The change in size of the valve can be configured to accommodate changes in size of the annulus from an infant or child to an adult.
Patent WO-2020198081-A1 (WO)
Title: Capteur à prisme à effet hall
Inventor: ANDERSON JOHN
IPC: G01R33/09
Filed: 2020-03-21
Abstract: Une fonction physiquement non clonable correspond à un objet qui a des caractéristiques qui le rendent extrêmement difficile voire impossible à copier. Un réseau de particules magnétiques dures (magnétisées) et molles (non magnétisées) dispersées de manière aléatoire pouvant être conductrices ou non conductrices qui sont versées dans un liant crée un champ magnétique ou un motif capacitif particulier sur la surface. Ce champ magnétique de surface et des variations capacitives peuvent être considérés comme un motif unique similaire à l'empreinte digitale. Le prisme à effet Hall est un capteur qui mesure les effets de ces motifs en détectant la déformation de courants ou d'un potentiel électrique circulant à l'intérieur ou autour d'un matériau de substrat résistif qui présente un coefficient d'effet Hall non négligeable.
Patent WO-2020226870-A1 (WO)
Title: Split heating, ventilation and air-conditioning (hvac) assembly
Inventor: PARIKH DARSHAN
IPC: F16B5/00
Filed: 2020-04-16
Abstract: A split heating, ventilation, and air-conditioning (HVAC) assembly for a motor vehicle is disclosed. The split HVAC includes a first sub-assembly comprising an evaporator and a first airflow space, a second sub-assembly comprising a second airflow space, a single sealing element located between a wall and one of the first sub-assembly or the second-sub- assembly, and a first interfacing element that directly connects the first sub-assembly and the second sub -assembly. The single sealing element and the first interfacing element prevent any airflow leakage from both the first sub-assembly and the second sub -assembly, and one of the first sub-assembly and the second sub-assembly extends partially into the other of the first sub-assembly and the second sub-assembly.
Patent WO-2020215001-A1 (WO)
Title: Method and apparatus for treating a sulfur dioxide containing stream by hydrogen sulfide in aqueous conditions
Inventor: RAYNEL GUILLAUME
IPC: B01D53/78
Filed: 2020-04-17
Abstract: Embodiments of the disclosure include systems and processes for the recovery of sulfur dioxide (SO 2 ) from tail gas of sulfur recovery plant or from flue gas of a power plant, such as flue gas originating from an H 2 S-containing fuel gas for a gas turbine. SO 2 -containing gas is dissolved in chilled water and produce SO 2 -containing chilled water. The SO 2 -containing chilled is contacted with H 2 S-containmg gas to aqueously react H 2 S and SO 2  and form elemental sulfur. A water stream, with the entrained sulfur is routed to a solid-liquid separate, and separated sulfur may be processed or disposed of. The water is recycled and chilled for use in the reaction. Embodiments also include the generation of sulfur dioxide (SO 2 ) from produced sulfur instead, of using tail gas or flue gas.
Patent WO-2020220005-A1 (WO)
Inventor: VAN STRATEN GEORGE
IPC: H05B35/00
Filed: 2020-04-25
Abstract: An electromagnetic illuminator heater is provided having a heat generating wire and an elongate encasement of thermally transmissive, temperature mitigating, and electrically insulative material. The material encompasses the elongate heating wire. A heater for devices is also provided.
Patent WO-2020256835-A1 (WO)
Inventor: QIU HONGHAO
IPC: G06Q10/00
Filed: 2020-04-28
Abstract: Techniques for providing a context aware productivity assistant in a computing device are disclosed. One example technique includes upon receiving a user input from a user for assistance with a task, analyzing the received user input in light of context data of an in-focus email to identify the task to be performed and automatically performing the identified task by requesting a computing service to execute the identified task with at least some of the received context data of the email and providing data representing a result of executing the identified task by the computing service to the email client. As such, the identified task can be automatically performed without inquiring the user for additional information.
Patent WO-2021011057-A1 (WO)
Inventor: HAMPTON THOMAS
IPC: A01K1/00
Filed: 2020-05-12
Abstract: A disposable and multiconfigurational animal habitat for obtaining physiological measurements of a small mammal is provided. The habitat includes a disposable and vertically oriented tower having a top, middle, and a bottom section. The tower includes a first chamber and a second chamber. The first chamber is sized, shaped, and configured to house the small mammal and is disposed in the top section of the tower. A first instrumentation platform is disposed in the first chamber and configured to support the small mammal. The second chamber is also sized, shaped, and configured to house the small mammal and disposed underneath the first instrumentation platform. A second instrumentation platform disposed in the second chamber and configured to support the small mammal. The habitat can be assembled from a kit comprising sheet of foldable disposable material having cut-outs and fold lines that can be folded to form the tower of the habitat.
Patent WO-2020232100-A1 (WO)
Inventor: AL-RUBAII MOHAMMED MURIF
IPC: E21B49/00
Filed: 2020-05-13
Abstract: Methods, systems, and computer-readable medium to perform operations including: determining, in real-time, values of drilling parameters of a drilling system drilling a wellbore; calculating, based on the values of the drilling parameters, a cuttings concentration in an annulus of the wellbore (CCA); calculating, based on the calculated CCA and a mud weight (MW) of a drilling fluid, an effective mud weight (MWeff) of the drilling fluid; and controlling, based on the effective mud weight, a component of the drilling system to adjust at least one of the drilling parameters.
Patent WO-2021011127-A1 (WO)
Inventor: FLINTER STEPHEN
IPC: G06F16/27
Filed: 2020-06-10
Abstract: A method for storing platform-agnostic digital media rights on a blockchain includes: receiving a transaction message related to a payment transaction, wherein the transaction message is formatted according to one or more standards and includes at least a plurality of data elements, the plurality of data elements including a first data element storing a primary account number and a second data element storing a product identifier: identifying a digital content identifier mapped to the product identifier; identifying a digital token mapped to the primary account number; generating a new blockchain data entiy, wherein the blockchain data entry includes at least the digital token and the digital content identifier; and transmitting the new blockchain data entiy to at least one node of a plurality of nodes comprising a blockchain network.
Patent WO-2021045820-A1 (WO)
Title: Method and system of providing search results to users
Inventor: ØHRN ALEKSANDER
IPC: G06F16/95
Filed: 2020-06-17
Abstract: A method of and system for display of a search result ad include receiving over a network a search term for which a targeted notification d is to be generated, receiving data associated with the search term, generating a creative for the targeted notification based in part on the data received and the search term, determining targeting criteria for the targeted notification; and providing the creative and the targeting criteria to an advertising service over the network to enable displaying the targeted notification, wherein the targeted notification provides notification of search results available for the search term, and a landing page for the creative is a search engine results page (SERP) for the search term.
Patent WO-2021016037-A1 (WO)
Title: Sole structures including polyolefin plates and articles of footwear formed therefrom
Inventor: FARR ISAAC
IPC: A43B3/00
Filed: 2020-07-16
Abstract: Sole structures including a plate including a first polyolefin resin, and an edge portion comprising a second resin are disclosed herein. The edge portion is more flexible or less rigid than the plate. Articles of footwear formed from the sole structures are also provided. Methods of making the polyolefin resin compositions, plates, edge portions, sole structures, and articles of footwear are also provided. In some aspects, the first polyolefin resin composition includes an effective amount of a polymeric resin modifier.
Patent WO-2021016048-A1 (WO)
Title: Delay for handover, rrc re-establishment and rrc connection release with redirection in 2-step rach
Inventor: ISLAM MUHAMMAD NAZMUL
IPC: H04W36/00
Filed: 2020-07-16
Abstract: A connection establishment procedure such as a handover or re-establishment procedure including a 2-step random access procedure may be completed within a defined time period. The defined time period may be measured from a handover command or a determination that a user equipment (UE) has lost a connection to a base station. The defined period of time may depend on one or both of a synchronization signal block (SSB) to random access channel (RACH) association period or a SSB to RACH association pattern period. The UE may receive a handover command from a serving cell. The UE may perform a handover in response to receiving the handover command or a re-establishment procedure in response to detecting the lost connection within the defined time period. One or more base stations may reserve resources for the connection establishment procedure during the defined time period.
Patent WO-2021034458-A1 (WO)
Title: Controlled gate-source voltage n-channel field effect transistor (nfet) gate driver
Inventor: SHAH PULKIT
IPC: G06F13/38
Filed: 2020-07-27
Abstract: Controlling gate-source voltage with a gate driver in a secondary-side controller in a secondary-controlled converter is described. In one embodiment, an apparatus includes a provider field effect transistor (FET) coupled to a transformer and the secondary-side controller coupled to the transformer. The gate driver is integrated on the secondary-side controller and is configured to control the gate-source voltage and slew rate of the secondary-side FET.
Patent WO-2022025917-A1 (WO)
Title: Protections pour dispositifs électroniques
Inventor: CHIU CHIEN-CHIH
IPC: H05K5/03
Filed: 2020-07-31
Abstract: La présente invention concerne des protections pour dispositifs électroniques. Dans un exemple, une protection pour un dispositif électronique peut comprendre un substrat métallique léger comprenant une première surface. Une première couche d'oxydation micro-arc peut être présente sur la première surface du substrat métallique léger, la première couche d'oxydation micro-arc peut comprendre un colorant cationique lié à la première surface par l'intermédiaire d'un composé de pontage inorganique anionique.