baber/WOPTO huggingface dataset:
Patent CA-3020585-A1 (CA)
Title: Compositions de conjugues d'acides nucleiques cibles
Inventor: HEYES JAMES
IPC: C12N15/87
Filed: 2017-04-11
Abstract: L'invention concerne des conjugués qui comprennent une fraction de ciblage, un acide nucléique, et des groupes de liaison éventuels, ainsi que des intermédiaires synthétiques et des procédés synthétiques utiles pour préparer les conjugués. Les conjugués sont utiles pour cibler des acides nucléiques thérapeutiques dans le foie et pour traiter des maladies du foie, notamment l'hépatite (par exemple l'hépatite B et l'hépatite D).
Patent CA-3021793-A1 (CA)
Title: Compositions et methodes pour le traitement de troubles cutanes
Inventor: TAYLOR EMMA
IPC: A61P17/10
Filed: 2017-04-21
Abstract: L'invention concerne des compositions et des méthodes de traitement de l'acné et d'autres troubles cutanés impliquant l'utilisation de probiotiques. Dans certains aspects, les microbes inclus dans les probiotiques ont été modifiés ou sélectionnés pour le traitement de troubles cutanés spécifiques.
Patent CA-3022925-A1 (CA)
Title: Chassis roulant modulaire pour vehicule
Inventor: TRENNE RODNEY J
IPC: B62D21/00
Filed: 2017-05-19
Abstract: Il est décrit un appareil de châssis de véhicule comprenant un châssis-plateforme ayant une cloison avant, une cloison arrière et une partie constituant un poste de pilotage qui s'étend sur le plan longitudinal entre les cloisons avant et arrière. L'appareil de châssis de véhicule comprend également un châssis auxiliaire avant pouvant se monter sur la cloison avant, un châssis auxiliaire arrière pouvant se monter sur la cloison arrière et un module de commande pouvant se raccorder de manière fonctionnelle au châssis auxiliaire avant par l'intermédiaire de la cloison avant. Le châssis-plateforme comprend également une paire de compartiments à batterie latéraux disposés respectivement de chaque côté extérieur de la partie centrale constituant un poste de pilotage, s'étendant sur le plan longitudinal entre la cloison avant et la cloison arrière et adaptés pour recevoir de façon amovible un module de batterie prévu pour se brancher sur le châssis auxiliaire arrière, le châssis auxiliaire avant ou les deux.
Patent CA-3025633-A1 (CA)
Inventor: GAGGAR ANUJ
IPC: A61K31/7072
Filed: 2017-05-11
Abstract: The present invention relates to the treatment of hepatitis B virus infections using a NS5A  inhibitor and a NS5B inhibitor. More specifically, the present invention concerns ledipasvir and sofosbuvir for treating of hepatitis B virus infections and uses of compositions comprising same.
Patent CA-3026409-A1 (CA)
Title: Appareil de guidage pour entree tangentielle dans un espace suprachoroidal
Inventor: OBERKIRCHER BRENDAN J
IPC: A61F9/00
Filed: 2017-06-14
Abstract: Appareil comprenant un corps et une paire de pattes rigides s'étendant à partir du corps. Le corps comprend un élément de mise en prise conçu pour entrer en prise avec un instrument de déploiement. Les pattes sont parallèles entre elles. Chaque patte possède une pointe tranchante. Les pattes s'étendent toutes les deux le long d'un plan. Le corps délimite une ouverture de guidage. L'ouverture de guidage est orientée transversalement par rapport au plan associé aux pattes. L'ouverture de guidage est dimensionnée pour recevoir une canule ayant un profil globalement plat. L'ouverture de guidage est conçue pour guider la canule à travers une sclérotomie selon une orientation sensiblement tangentielle.
Patent CA-3027331-A1 (CA)
Title: Lidar rotatif
Inventor: MIREMADI REZA
IPC: G01C3/08
Filed: 2016-06-13
Abstract: Système lidar comprenant une base, un corps capteur, et un moteur ayant un arbre. Le moteur est fixé sur la base et peut entraîner le corps capteur en rotation par rapport à la base. Un dispositif DEL et un capteur de lumière sont tous deux montés sur le corps capteur. Un dispositif de traitement de données est également monté sur le corps capteur, et programmé pour produire des informations de portée sur la base des données de capteur. L'arbre porte deux bagues collectrices. La DEL, le capteur et le dispositif de traitement de données reçoivent tous de l'énergie électrique par l'intermédiaire des deux bagues collectrices. Le dispositif de traitement de données est conçu pour transmettre des informations de portée par l'intermédiaire des deux bagues collectrices à l'aide d'une modulation de largeur d'impulsions.
Patent CA-3028658-A1 (CA)
Inventor: MACKELVIE WINSTON
IPC: C08J5/12
Filed: 2018-12-28
Abstract: A composite of loose powdered plastic flow-coated onto the surface of a bond face material whose surface has multiple raised engaging structures. Bond face can be included in rotational molds to add desirable characteristics to the molded plastic article.  Bond faced components of metal, plastic, and wood, can be joined and co-joined with the plastic coating. Such constructions can include plies of glass- and other fabrics. The powdered plastic can include additives such as fibres, beads, grits and the like.
Patent CA-3029395-A1 (CA)
Inventor: FANG FANG
IPC: G06T7/20
Filed: 2016-06-30
Abstract: Provided is an object tracking method in which when a plurality of objects detected by an object detection unit (10) enter a concealed area calculated by a concealed area calculation unit (32), a positional relationship estimation unit (33) estimates the positional relationship of the plurality of objects within the concealed area on the basis of information relating to the plurality of objects and on the basis of traffic lanes and routes to which the objects can change course according to calculation by a route calculation unit (34). When an object exits the concealed area, an identification number assignment unit (35) determines identification information for the object on the basis of the positional relationship estimated by the positional relationship estimation unit (33).
Patent CA-3032778-A1 (CA)
Inventor: KOUNAVIS JOHN
IPC: C08L21/00
Filed: 2017-08-31
Abstract: A process is provided for making a silica masterbatch that contains silica and solution-made rubber. The silica masterbatch has physical properties similar to those found in a comparable dry-mixed composition, but the silica masterbatch can be incorporated more easily and less expensively into tires and other rubber products than the dry-mixed composition, A process is also provided for making a masterbatch of silica, a solution-made rubber and an emulsion-made rubber.
Patent CA-3036033-A1 (CA)
Inventor: TANG ZUPING
IPC: H04L27/20
Filed: 2017-01-19
Abstract: Disclosed are a method and apparatus for receiving a TD-AltBOC signal, belonging to the field of global satellite navigation. The method of the invention includes the following steps: converting a TD-AltBOC radio frequency signal into an intermediate-frequency and band-pass filtered signal and sampling same, and a local carrier being used for stripping a sampled signal carrier so as to obtain a sampled baseband signal; correlating a local waveform to the sampled baseband signal chip-by-chip in a time division manner; performing data demodulation according to a related output signal, and acquiring a carrier phase deviation estimation value and a code phase deviation estimation value according to the related output signal; generating the local waveform according to the code phase deviation estimation value; and generating the local carrier according to the carrier phase deviation estimation value. The present invention also achieves a receiving apparatus for a TD-AltBOC signal. The technical solution of the present invention is easy to implement, the receiving complexity is reduced, and hardware resources are saved.
Patent CA-3036314-A1 (CA)
Title: Organic waste odor absorber
Inventor: DAVIS SHAWN S
IPC: C05F9/04
Filed: 2019-03-11
Abstract: An organic waste odor absorbing composition for the absorption of odors resulting from decomposing organic waste is disclosed. The composition comprises dried carbon and/or silica based matter, either natural or synthetic. The carbon-based materials consist of 35% to 85% holocellulose and 8% to 30% lignin. The silica-based materials consist of 40% to 80% silica. The materials may be mechanically sized to allow for adequate airflow and surface area exposure to the organic waste.
Patent CA-3036632-A1 (CA)
Title: Traitement de la migraine refractaire
Inventor: BIGAL MARCELO
IPC: A61P25/06
Filed: 2017-09-22
Abstract: L'invention concerne des méthodes de traitement ou de réduction de l'incidence d'une migraine et/ou au moins un symptôme secondaire associé à une migraine réfractaire chez un sujet souffrant de migraine réfractaire consistant à administrer au sujet un anticorps monoclonal 5 qui module la voie CGRP. L'invention concerne également des compositions destinées à être utilisées dans les méthodes de l'invention. L'invention concerne en outre l'anticorps antagoniste G1 et des anticorps dérivés de G1 dirigés contre le CGRP.
Patent CA-3036757-A1 (CA)
Title: Novel regimes of fxr agonists
Inventor: LAFFITTE BRYAN
IPC: A61K31/55
Filed: 2017-09-12
Abstract: The invention provides novel regimens of farnesoid X receptor (FXR) agonist and methods for modulating the activity of farnesoid X receptors (FXRs) using novel regimes of specific FXR agonists, in particular for treating or preventing fibrotic or cirrhotic diseases or disorders, such as liver diseases.
Patent CA-3038859-A1 (CA)
Inventor: MIRACLE GREGORY SCOT
IPC: C11D3/40
Filed: 2017-11-01
Abstract: A method for treating textile articles includes the steps of: (a) providing a laundry care composition comprising a leuco composition; (b) adding the laundry care composition to a liquid medium; (c) placing the textile articles in contact with the liquid medium; (d) depositing at least some portion of the leuco composition onto the textile articles; (e) optionally, rinsing the textile; and (f) drying the textile articles, wherein the textile articles after 1 day of storage provide a whiteness benefit to cotton that is greater than the initial whiteness benefit achieved after drying.
Patent CA-3039194-A1 (CA)
Inventor: SWARUP SHANTI
IPC: C09D5/00
Filed: 2017-10-18
Abstract: A curable film-forming composition is provided, comprising: (a) a polymeric polyester binder comprising a plurality of carbamate groups; (b) a curing agent reactive with the carbamate functional groups of (a); and (c) a reaction product of: (1) a hydroxyl functional polymer comprising the reaction product of: (i) a monomer comprising at least two ethylenically unsaturated double bonds; (ii) a monomer comprising a carbon atom that is bonded to four moieties wherein one of the moieties is a hydrogen atom and the remainder of the moieties comprises an alkyl group, wherein at least one of the alkyl group-containing moieties comprises an ethylenically unsaturated double bond; and (iii) at least one monomer that is polymerizable with (i) and (ii); and (2) a lactone or lactam. Also provided are a multi-component composite coating composition that includes the curable film-forming composition described above and methods for forming a composite coating on a substrate.
Patent CA-3040912-A1 (CA)
Inventor: PAGENKOPF KENNETH EDWARD
IPC: H02M5/10
Filed: 2017-10-18
Abstract: Enhanced common mode current reduction in three-phase inductors, transformers, and motor drive systems. A motor drive system includes an iron core transformer, a common-mode transformer coupled to a three-phase motor, and a variable speed drive providing a three-phase power signal to drive the three-phase motor, and coupled to the iron core transformer and the common mode transformer. The system includes a DC bus having a DC bus midpoint. The common-mode transformer includes a toroidal ferrite core, a first choke winding, a second choke winding, a third choke winding, a first coupling winding collocated with the first choke winding, a second coupling winding collocated with the second choke winding, and a third coupling winding collocated with the third choke winding. The first, second, and third coupling windings are coupled in parallel to one another. The coupled windings couple a neutral point of the iron core transformer to the DC bus midpoint.
Patent CA-3040914-A1 (CA)
Title: Polytherapie de therapie cellulaire et d'inhibiteur de la microglie
Inventor: LEVITSKY HYAM I
IPC: A61K31/444
Filed: 2017-11-03
Abstract: L'invention concerne des méthodes, des kits et des compositions d'amélioration de toxicité, telle que le syndrome de libération de cytokines ou une neurotoxicité, suspectée ou étant induite par une administration d'un agent thérapeutique tel qu'un agent immunothérapeutique ciblant des lymphocytes T et/ou des lymphocytes T génétiquement modifiés, par exemple des lymphocytes T exprimant un récepteur d'antigène chimère (CAR), ou étant associée à cette dernière. Les méthodes impliquent une administration d'un agent supplémentaire, tel qu'un agent ayant des propriétés antioxydantes ou anti-inflammatoires, qui module des cellules immunitaires telles que par prévention ou réduction de la production de cytokines pro-inflammatoires ou de cytokines de stress et/ou favorisant la différenciation en un phénotype neuroprotecteur, et/ou pouvant prévenir, bloquer ou réduire une activation ou une fonction des cellules microgliales et/ou pouvant moduler, comme promouvoir, l'activité de NRF2 ou d'un constituant d'une voie régulée par NRF2, et/ou d'un ou de plusieurs constituants impliqués dans un élément de réponse antioxydant (ARE). Les méthodes selon l'invention peuvent être utilisées en association avec des méthodes de traitement d'une maladie ou d'une affection, ou pour ces dernières.
Patent CA-3042073-A1 (CA)
Title: Injectable vaccines against multiple meningococcal serogroups
Inventor: CONSTANTINO PAOLO
IPC: C07K14/285
Filed: 2004-01-30
Abstract: An injectable immunogenic composition and uses thereof are described. The composition comprises capsular saccharides from N meningitidis serogroups A, C, W135 and Y, wherein: (i) each of said capsular saccharides is conjugated to a carrier protein to give separate conjugates for each of the four serogroups; (ii) the total of the capsular saccharides from the N.meningitidis serogroups A, C, W135 and Y per dose of the composition is between 10 µg and 25 µg; and (iii) the capsular saccharides from the N.meningitidis serogroups A, C, W135 and Y are present at a 2:1:1:1 capsular saccharide weight ratio.
Patent CA-3044186-A1 (CA)
Title: Rolling plate assembly attachment for portable power cutting tools including an improved structural design, improved wheel configuration, and a cutting guide
Inventor: KNIGHT ERIC
IPC: B23D51/02
Filed: 2019-05-24
Abstract: The present invention is an attachable rolling plate assembly which can be attached as a single unit to a portable cutting tool to facilitate the safe rolling movement of the portable cutting tool on the workpiece. The invention comprises a frame assembly formed from a single piece of molded material such as fiber enriched high-impact nylon having a pair of oppositely disposed longitudinal sidewalls with damping strips extending therefrom, and a flat base portion having an opening through which a saw blade of a power saw extends. The plate has front and rear fastening members to retain a plate of a power cutting saw onto the rolling plate assembly. The invention also includes a cutting guide assembly to facilitate a straight cut, reduce torsional rotation of the saw blade and reduce kickback of the saw.
Patent CA-3044556-A1 (CA)
Inventor: BERDEL WOLFGANG
IPC: C07K16/28
Filed: 2017-04-12
Abstract: The present invention relates to a combination comprising at least fusion protein comprising a binding protein specifically recognizing a cancer-related antigen and an inflammatory cytokine, and a chimeric antigen receptor (CAR)-T cell recognizing a cancer-related antigen
Patent CA-3044558-A1 (CA)
Title: Method of locating a fault in a power transmission scheme
Inventor: HA HENGXU
IPC: G01R31/08
Filed: 2017-11-03
Abstract: In the field of power transmission schemes there is provided a method of locating a fault in a multi-terminal electrical power transmission scheme (10) in which each terminal (T1, T2, T3, T4, T5, T6) is connected with a junction (J1, J2, J3, J4) via a power transmission section (12) and the or each junction (J1, J2, J3, J4) interconnects a plurality of power transmission sections (12), the method comprising the steps of: (a) measuring the voltage and current at each terminal (T1, T2, T3, T4, T5, T6); (b) calculating from the measured voltage and current at each terminal (T1, T2, T3, T4, T5, T6) corresponding voltage and current phasors (V1, I1, V2, l2); (c) determining from the calculated voltage and current phasors (V1, I1) a synchronisation difference (Tp1, Tp2, Tp3, Tp4, Tp5) between the measured voltage and current at a designated terminal (T1 ) and the measured voltage and current at the or each other terminal (T2, T3, T4, T5, T6); (d) modifying the calculated voltage and current phasors (V1, I1) to compensate for the or each synchronisation difference (Tp1, Tp2, Tp3, Tp4, Tp5); and (e) determining from the compensated voltage and current phasors (VTSyn, ITSyn) the location of the fault.
Patent CA-3052865-A1 (CA)
Inventor: FURLONG MITCHELL
IPC: F16L59/02
Filed: 2019-08-23
Abstract: An insulating member comprises a body of rigid foam material having a first connecting edge surface and a second connecting edge surface, a groove formed into the rigid foam material of the body along the first connecting edge surface, and a tongue formed from the rigid foam material of the body along the second connecting edge surface.  The groove, when viewed in a transverse cross-section, tapers from narrow to wide in a direction extending from its opening and into the body. The tongue, when viewed in a transverse cross-section. tapers from wide to narrow in a direction toward the second connecting edge surface. The tongue is bifurcated along its length into first and second ridges by a wedge-shaped void. A polymer coating of polyurea or polyurethane substantially covers the tongue and structurally reinforces the tongue allowing the first and second ridges to flex toward one another without breaking.
Patent CA-3053197-A1 (CA)
Title: Suivi et disponibilite des avantages dans un systeme de base de donnees d`admission
Inventor: EVANCZUK ALEXANDER
IPC: G06F16/90
Filed: 2019-08-26
Abstract: Un système de base de données dadmission central affiche, sur un dispositif client, une interface davantages dune personne qui fait partie dune organisation. Linterface davantages comprend une pluralité davantages correspondant à une organisation dont la personne fait partie. Le système de base de données dadmission central détermine un premier ensemble de la pluralité davantages dans lequel un ensemble de règles dadmissibilité correspondant à chacun des avantages de lensemble est respecté et dans lequel un deuxième ensemble de la pluralité davantages, dans lequel in ensemble de règles dadmissibilité correspondant à chacun des avantages du deuxième ensemble nest pas satisfait par lensemble de données accédé sur le personnel. Le système de base de données dadmission central modifie linterface davantages pour indiquer que la personne est admissible au premier ensemble davantages, que la personne nest pas admissible au deuxième ensemble davantages, et aux règles dadmissibilité correspondantes.
Patent CA-3053549-A1 (CA)
Inventor: HAGAR AMIT
IPC: A61B5/00
Filed: 2017-02-17
Abstract: The present disclosure is directed towards methods for calculating disease progression rates and sojourn times of solid tumors from metabolic markers and using this calculation to optimize patient-specific diagnosis, scheduling of screening procedures, and dosage or frequency of treatment.
Patent CA-3053583-A1 (CA)
Inventor: GIBSON DEANNA
IPC: A61K35/741
Filed: 2018-02-19
Abstract: The present invention relates to probiotic compositions. More specifically, the present invention relates to probiotic compositions that are useful in reducing inflammation and/or that exhibit increased colonization or persistence in the gastrointestinal tract of a mammal.
Patent CA-3053740-A1 (CA)
Inventor: KLEPPA ERLING
IPC: E21B33/03
Filed: 2018-02-27
Abstract: A wellhead port plug assembly (100) having a sensor unit (200), a plug (400), a transmitter unit (220) arranged in the sensor unit (200) and comprising a wireless signal transmitter (236), and a receiver unit (600) arranged on the spool unit (102) and comprising a wireless signal receiver (636). There is also disclosed a method for installing, removing or replacing a sensor unit (200) located in a port (301) of a wellhead (300).
Patent CA-3054337-A1 (CA)
Inventor: JI YANSHAN
IPC: C12Q1/68
Filed: 2018-03-08
Abstract: Provided are methods and compositions for preserving tissue samples containing nucleic acids, including DNA, at ambient temperatures and without the need for cold sampling or cold storage. After storage, the preserved DNA in the samples may then be processed and analyzed by known methods, e.g., PCR. The present invention provides in one aspect, a method for simple and rapid storage and/or processing of nucleic acids, such as DNA, from various sources, including but not limited to plants, tissues, bacterial cell lysates containing plasmids, etc. The present invention further comprises reagents and methods employing glycerol at alkaline pH to process biological samples and make DNA usable in PCR without further sample purification. Accordingly, the present invention provides in one aspect, a method for simple and rapid processing of nucleic acids, such as DNA, from various sources, including but not limited to plants, tissues, bacterial cell lysates containing plasmids, etc.
Patent CA-3056234-A1 (CA)
Inventor: HABBOUSHE JOSEPH
IPC: A61K31/616
Filed: 2018-03-15
Abstract: Provided are compositions and methods for treating multiple sclerosis (MS). One embodiment of the disclosed method entails orally administering to a MS patient a first amount of aspirin and a second amount of fumaric acid or an ester or a salt thereof. In some embodiments, the aspirin is administered at from about 80 mg to about 500 mg per day and the fumaric acid or ester or salt thereof is administered at about 360 mg per day.
Patent CA-3058347-A1 (CA)
Title: Absorbent laminated material
Inventor: DAVIS MARTYN
IPC: B32B37/16
Filed: 2017-05-16
Abstract: Absorbent laminated materials that include two spunbond nonwoven layers with a cellulose layer arranged in between the spunbond nonwoven layers are disclosed. The different layers of the absorbent laminated material are bonded through an ultrasonic treatment, and can further undergo an embossing step. In addition, the absorbent laminated materials may be used as disposable wiping products, among other applications.
Patent CA-3061044-A1 (CA)
Title: Methods and materials for treating cancer
Inventor: Kim Yon Son Betty
IPC: A61K39/395
Filed: 2018-04-26
Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for using a BiPE that can include (a) one or more molecules having the ability to bind to a cancer cell (e.g., a human breast cancer cell), (b) an optional linker component, and (c) one or more molecules having the ability to bind to an antigen presenting cell (e.g., a human macrophage) to treat cancer are provided.
Patent CA-3062170-A1 (CA)
Inventor: SORGENTE NINO
IPC: C07K5/062
Filed: 2018-05-03
Abstract: Provided herein are anti-aging compositions and methods for maintaining and/or improving eye health in a subject, comprising administering to the eye of the subject a therapeutically effective amount of a compound that modulates the ATP-sensitive K+ channel and a pharmaceutically acceptable carrier. A method of treating glaucoma in a patient, comprising: obtaining a biological sample from the patient; testing the biological sample for presence of a mutation in Kir6.2 protein or KCNJ11 gene; and provided that the biological sample tests positive for the presence of a mutation in Kir6.2 protein or KCNJ11 gene, administering to the patient a therapeutically effective amount of a compound that specifically inhibits the Kir6.2 ATP-sensitive K+ channel and a pharmaceutically acceptable carrier.