baber/WOPTO huggingface dataset:
Patent FI-943999-A0 (FI)
Inventor: JAETSCH THOMAS
IPC: A61K31/535
Filed: 1994-08-31
Abstract: The present invention relates to novel pyrido[1,2,3-d,e][1,3,4]benzoxadiazine derivatives of the formula (I)   <IMAGE>  in which   R<1> is hydrogen or C1-C4-alkyl which is optionally substituted by hydroxyl or halogen,   R<2> independently of R<1> is hydrogen or methyl,   R<3> is hydrogen or C1-C4-alkyl, R<4> is hydrogen, alkyl having 1 to 4 carbon atoms, which is optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino, or (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl,   X<1> is hydrogen or halogen,   Z is a radical of the structure   <IMAGE>  wherein   R<7> is hydrogen, hydroxyl, -NR<10>R<11>, hydroxymethyl or -CH2-NR<10>R<11>, carboxyl, methoxycarbonyl or ethoxycarbonyl, where R<10> is hydrogen, C1-C3-alkyl which is optionally substituted by hydroxyl, or alkoxycarbonyl having 1 to 4 C atoms in the alkoxy moiety or C1-C3-acyl, and   R<11> is hydrogen or methyl, R<8> is hydrogen, straight-chain or branched C1-C3-alkyl or cyclopropyl,   R<9> is hydrogen or methyl,   R<6> is hydrogen or methyl, R<5> is hydrogen, methyl or radicals of the structures -CH=CH-CO2R<5'>, -CH2-CH2-CO2R<5'>, -CH2-CO-CH3, -CH2-CH2-CN,   R<5'> is methyl or ethyl,   B is -CH2-, O or a direct bond, their preparation and their use for the therapy or prevention of bacterial infections.
Patent FI-951887-A0 (FI)
Inventor: WOLTER KARIN
IPC: A61K47/30
Filed: 1995-04-20
Abstract: The invention relates to a patch for transdermal administration of volatile pharmaceutically active ingredients of chemically basic nature which comprises a multi-element system comprising   (a) a matrix having distributed therein as the drug said volatile active ingredient or a physiologically acceptable salt thereof, the matrix comprising a pressure-sensitive adhesive, (b) an element of a pressure-sensitive adhesive composition which - where (a) contains a salt - contains basic groups to liberate the free base from its salt, (c) a backing layer impermeable to the diffusable ingredients of (a) and (b), and (d) a release liner impermeable to the diffusable ingredients of (a) and (b), matrix (a) or at least a part of (b), whichever is in contact with release liner (d), having a tack sufficient for affixing the patch to the skin, any part of (b) positioned between matrix (a) and release liner (d) being permeable for the deprenyl or the salt thereof or both. The invention also relates to a process for preparing such patch. <IMAGE>
Patent FI-970942-A0 (FI)
Inventor: DAINTON ALBERT EDWARD
IPC: B22D11/10
Filed: 1997-03-05
Abstract: PCT No. PCT/GB95/01934 Sec. 371 Date Mar. 5, 1997 Sec. 102(e) Date Mar. 5, 1997 PCT Filed Aug. 16, 1995 PCT Pub. No. WO96/07495 PCT Pub. Date Mar. 14, 1996A flow control device for the outlet nozzle for a molten metal handling vessel, such as a ladle, includes a plug that fits in the outlet nozzle to define a gap between the plug and a closure for the nozzle. The plug has a plurality of apertures which are closed by steel plates, or other material, that melts under the influence of the molten metal in the vessel. When molten metal is placed into the vessel and the closure for the outlet is opened, the molten metal flows into the apertures, melting the meltable material in the apertures, and out the outlet. Using a device and method described allows the amount of molten metal in a ladle to be reduced to about 0.5%, and a greater than 99% free opening rate can be provided.
Patent IL-99487-A0 (IL)
Title: Abrasive tool
IPC: B24D5/12
Filed: 1991-09-15
Abstract: An abrasive tool such as a grinding wheel or a saw is characterized by the working portion comprising a mass of ultra-hard abrasive particles dispersed in a non-porous thermoplastic polymer matrix. Examples of suitable thermoplastic polymers are polyetheretherketone, polyaryletherketone, poly (amide-imide), polyphenylene sulphide, liquid crystal polymer and mixtures thereof.
Patent AU-PQ304199-A0 (AU)
Title: Patterned carbon nanotubes
IPC: G01Q70/12
Filed: 1999-09-23
Abstract: A process for preparing a patterned layer of aligned carbon nanotubes on a substrate including: applying a pattern of polymeric material to the surface of a substrate capable of supporting nanotube growth using a soft-lithographic technique; subjecting said polymeric material to carbonization to form a patterned layer of carbonized polymer on the surface of the substrate; synthesising a layer of aligned carbon nanotubes on regions of said substrate to which carbonized polymer is not attached to provide a patterned layer of aligned carbon nanotubes on said substrate.
Patent FI-20115723-A0 (FI)
Inventor: LINDBERG TEEMU
IPC: C07C/
Filed: 2011-07-06
Abstract: The present invention relates to a process and an apparatus for purifying tall oil material for the production of biofuels and components thereof. The present invention relates further to hydroprocessing of the purified material to obtain biofuels and components thereof.
Patent IL-101700-A0 (IL)
Title: Benzoisothiazole and benzoisoxazole-3-carboxamides,a process for their preparation and their use as medicaments
IPC: C07D413/12
Filed: 1992-04-27
Abstract: The present invention relates to benzisothiazole- and benzisoxazole-3-carboxamides of the formula I <CHEM> wherein R<1> is hydrogen or loweralkyl; R<2> is loweralkyl, or a group of the formula <CHEM> R<3> is hydrogen or loweralkyl; A is loweralkylene, a group of the formula -CHR<4>CH=CHCHR<4>-, or -CHR<4>C IDENTICAL CHR<4>-; R<4> is hydrogen or loweralkyl; X is O or S; W is N or CH; Y is hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, or trifluoromethyl; Z is hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, or trifluoromethyl; n is 1 or 2; wherein the solid line (-) refers to the point of attachment of the group to the indicated member of the formula; the geometric and optical isomers thereof; or a pharmaceutically acceptable salt thereof, useful for the treatment of psychoses, alone or in combination with inert adjuvants.
Patent IL-106396-A0 (IL)
Title: Pseudo-half-knot rna formation by hybridization of antisense oligonucleotides to target rna's secondary structure
IPC: A61K48/00
Filed: 1993-07-19
Abstract: Compositions and methods for modulating the activity of RNA are provided. Oligonucleotides are hybridized with an RNA structure to form a stable heteroduplex so that the RNA is no longer recognized by its regulatory protein after oligonucleotide binding. Reactive moieties can be tethered to the oligonucleotide that enhance its activity. Antisense oligonucleotides directed against HIV TAR are provided.
Patent IL-122896-A0 (IL)
Title: Preparation of aldehydes or ketones from alcohols
IPC: C07C45/37
Filed: 1996-07-04
Abstract: PCT No. PCT/GB96/01607 Sec. 371 Date Nov. 12, 1997 Sec. 102(e) Date Nov. 12, 1997 PCT Filed Jul. 4, 1996 PCT Pub. No. WO97/03033 PCT Pub. Date Jan. 30, 1997A process for preparing an aldehyde or ketone comprising reacting a primary or secondary alcohol with oxygen in the presence of a base, a catalytic amount of a copper salt and a suitable lignad under anhydrous conditions.
Patent IL-125251-A0 (IL)
Title: Electrically screening housing
IPC: H05K9/00
Filed: 1997-01-20
Abstract: The invention concerns an electrical screening housing for accommodating components or assemblies which emit electromagnetic radiation or are sensitive thereto, and for providing electromagnetic screening for the components or assemblies. The housing includes at least two parts with electrically screening walls, a sealing element being provided in an adhesive manner on at least one housing part in the region of a joint with the other housing part. The sealing element and at least one portion of the housing part bearing the latter are made of substantially non-conductive material and, for electromagnetic screening purposes, are covered with a cohesive, electrically conductive layer which extends at least over the entire width of the joint and adheres to the joint element and the housing part.
Patent IL-125450-A0 (IL)
Title: Lipopeptides from actinoplanes sp with pharmacological action process for their preparation and the use thereof
IPC: A61K38/12
Filed: 1998-07-21
Abstract: Lipo-peptides of formula (I), where R1 is a saturated or unsaturated, branched or unbranched, 6-22C fatty acid or hydroxy fatty acid residue other than those of formula (II)-(VII), are new:
Patent IL-126600-A0 (IL)
Title: Biocidal composition and method for treating raw materials products and means of production
IPC: A01N59/00
Filed: 1997-04-17
Abstract: The invention relates to a composition for decontaminating raw materials, products, water and/or production means, which composition is prepared from at least hydrogen peroxide, glycerol and glycol acid, a method for the preparation thereof, comprising mixing a solution of glycerol and a solution of glycol acid, and dropwise adding the mixture obtained to a solution of hydrogen peroxide under such conditions that the solution of hydrogen peroxide maintains a temperature of 7 DEG C and preferably below 4 DEG C. Further, the invention relates to a method for decontaminating objects.
Patent IL-127481-A0 (IL)
Title: Incontinence treatment device
IPC: A61F/
Filed: 1998-12-09
Abstract: 1A device for treatment of urinary incontinence comprises: at least one electrode, which is coupled to a pelvic muscle of a patient; and a control unit, which receives electromyogram signals from the electrode indicative of possible imminent incontinence, and which determines a threshold signal level that varies over time responsive to a condition of the patient, and which, responsive to a transient increase in the electromyogram signal above the threshold level, applies an electrical waveform to stimulate the muscle to contract, so as to inhibit the incontinence.
Patent IL-131675-A0 (IL)
Title: Supporting means for a screening device
IPC: E06B9/52
Filed: 1998-08-12
Abstract: A supporting mechanism for a window screening device comprises a first pair of bracket members for mounting on each of a pair of opposed parallel frame surfaces of the frame structure and a second pair of coupling members engageable by the screening device. Each bracket member and each coupling member comprises an engaging mechanism for releasable sliding engagement of a coupling member with a bracket member. Each bracket member or each coupling member is provided with a resilient mechanism engageable with an abutment of a coupling member or a bracket member to retain the bracket member and the coupling member in mutual engagement. The bracket members are identical standard members each comprising a relatively flat front part protruding from said frame surface and having a substantially smooth external surface and engaging mechanism formed by a pair of opposed parallel side edges. Each coupling member is formed as a substantially flat brick-shaped member provided with an open recess limited by leg portions forming engaging mechanism engageable with the engaging mechanism on the bracket members.
Patent IL-132945-A0 (IL)
Title: Filtering material and device and method of its manufacture
IPC: D01D5/00
Filed: 1999-11-15
Abstract: A device and method for producing a porous fiber structure. One or more points of high surface curvature is produced in a liquefied polymer, such as a polymer solution or a polymer melt. The points of high surface curvature may be produced by forcing the liquefied polymer through narrow nozzles, or by wetting sharp protrusions with the liquefied polymer. The liquefied polymer is charged to a high negative electrical potential relative to a grounded moving belt. Thin jets of liquefied polymer emerge from the points of high surface curvature to impinge as fibers on the moving belt, thereby forming an unwoven fiber structure of relatively uniform porosity. A powdered aerosol is charged to a high positive electrical potential relative to the moving belt. As the belt moves past the aerosol, the aerosol particles are attracted to fill interstices in the fiber structure, thereby creating a composite filtering material.  <IMAGE>
Patent IL-138275-A0 (IL)
Title: Pressure control system for cardiac assist device
IPC: A61M60/531
Filed: 1998-11-30
Abstract: A control system for an inflatable chamber operably positionable with respect to an aorta of a patient monitors an actual flow duration time for inflating and/or deflating the inflatable chamber with a predetermined volume of pressurized fluid and compares the actual flow duration time to a target flow duration time. The system controls the fluid pressure in a high pressure reservoir, and/or in a vacuum reservoir, based on the results of the comparison. If the actual time for inflation is too short compared to the target time, the fluid pressure in the high pressure reservoir is reduced. If the actual time for inflation is too long compared with the target time, the fluid pressure in the high pressure reservoir is increased. If the actual time for deflation is too short compared to the target time, the vacuum in the vacuum reservoir is decreased. If the actual time for deflation is too long compared with the target time, the vacuum in the vacuum reservoir is increased. The incremental step change in fluid pressure within either reservoir can be controlled within predetermined minimum and maximum values, and/or based on the magnitude of the difference between the actual and target time intervals. The change in fluid pressure within either reservoir can be controlled by the system manipulating a control valve, or varying the speed of the compressor, or any combination of the two, until the new calculated value is reached within the reservoir.
Patent IL-138685-A0 (IL)
Title: Liposome composition and method for administering a quinolone
IPC: A61K47/48
Filed: 1999-03-24
Abstract: A liposome composition for treating a bacterial infection is described. The composition includes liposomes having a surface coating of hydrophilic polymer chains and an entrapped drug-conjugate composed of ciprofloxacin conjugated to an amino acid.
Patent IL-139816-A0 (IL)
Title: Continuous polyamidation process
IPC: C08G69/26
Filed: 1999-05-26
Abstract: A process for producing a polyamide from dicarboxylic acid monomer and diamine monomer comprises the steps of: (a) mixing molten dicarboxylic acid monomer and molten diamine monomer in equimolar amounts, thereby producing a molten reaction mixture; (b) flowing the reaction mixture through at least one unvented reaction vessel, the residence time of the reaction mixture in the at least one unvented reaction vessel being between about 0.01 minutes and about 30 minutes, thereby forming a first product stream that comprises polyamide and water of polymerization; and (c) flowing the first product stream through at least one vented vessel, whereby water of polymerization is removed, thereby forming a second product stream that comprises polyamide. The process can operate continuously, and there is no need to add water to the dicarboxylic acid, to the diamine, or to the reaction mixture.
Patent IL-141658-A0 (IL)
Title: Gas diffusion structure perpendicular to the membrane of polymer-electrolyte membrane fuel cells
IPC: H01M8/0245
Filed: 1999-09-02
Abstract: Not all gas diffusion structures known to date can guarantee water balance compensation in the fuel cell, protection against drying and prevention of water deposits while simultaneously ensuring even distribution of reaction gases. In the gas diffusion structure, according to the invention, a gradient is produced in terms of gas permeability perpendicular to the membrane by way of a stratified system. This guarantees, at an appropriate operating temperature and appropriate stoichiometry of the reactants, constant and optimal humidification in all points of the membrane by the formed product water. Additional humidification systems can thus be discarded.
Patent IL-145174-A0 (IL)
Title: Diamond coated tool and processes for the preparation thereof
IPC: B23B27/14
Filed: 2000-03-31
Abstract: The invention relates to a coated component, in particular a coated tool for machining, having a substrate and a first carbon layer, which is applied to the substrate and has a predetermined fraction of carbon with a diamond crystal structure. There is the problem with such a component that the adhesive strength of the first carbon layer on the substrate is unsatisfactory in many instances. This problem is solved by virtue of the fact that provision is made of a second carbon layer, which is arranged further outside with reference to the substrate than the first carbon layer, and in the case of which the fraction of carbon with a diamond crystal structure is lower than the predetermined fraction of carbon with a crystal diamond structure in the first carbon layer. The invention also relates to a process for producing such a coated component.
Patent IL-145429-A0 (IL)
Title: N-cyanomethyl amides, processes for the preparation thereof and pharmaceutical compositions containing the same
IPC: A61P3/10
Filed: 2000-03-15
Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
Patent IL-146679-A0 (IL)
Title: Signature capture via interface surface
IPC: G06F3/0354
Filed: 2000-05-24
Abstract: A system for enabling user interaction is disclosed. The system includes a printer for printing print data on a form. The print data is indicative of a plurality of marks. Each mark has a predetermined pattern common to all marks and coded data. The predetermined pattern includes a rotationally invariant pattern. A sensing device is also included for sensing the marks when moved relative to the form, for using the rotationally invariant pattern to correct for perspective distortion of the marks, for decoding the coded data of the marks, and for generating indicating data indicative of movement of the sensing device relative to the form.
Patent IL-148089-A0 (IL)
Title: Baff receptor (bcma), an immunorgulatory agent
IPC: C07K14/715
Filed: 2000-08-16
Abstract: A receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
Patent IL-164098-A0 (IL)
Title: Methods and compositions for analysis of urine samples in the diagnosis of kidney diseases
IPC: C12Q/
Filed: 2003-03-27
Abstract: The invention comprises novel compositions, systems, and methods for the analysis of biological samples, such as urine samples, in order to diagnose and treat kidney disease, including without limitation, glomerulonephritis, nephrotic syndrome, diabetes, lupus, hypertension, acute tubular necrosis, obstructive disorders of the urinary tract, renal cancers and other diseases or syndromes. In preferred embodiments, the invention comprises the identification of particular genes expressed only in cells of particular clinical or scientific interest in the urinary tract, such as podocytes or proximal tubule cells. Thus, the invention enables non-invasive, rapid and accurate analysis of kidney and urinary tract status and function in many medical diseases and disorders.
Patent IL-192964-A0 (IL)
Title: Tumour vaccine comprising allogeneic or xenogeneic tumour cells
IPC: A61K35/30
Filed: 2008-07-22
Abstract: The present invention provides a composition for the treatment of a tumor, comprising: (i) allogeneic or xenogeneic tumor cells; and (ii) a pharmaceutically acceptable excipient. If two or more heterozygous individuals have the same cancer/tumor of the same or similar histological grade, then transplantation of tumor/cancer tissue/cells from one individual to another will not only induce rejection of the transplanted tissue/cancer, but will also increase the immunological awareness of the immune system to peptides shared between the tumors/cancers and other tumors possessing similar peptides.
Patent RO-129112-A0 (RO)
Title: Bearing profile for false ceilings and walls and installation for making the same
Inventor: TOMA MARCEL
IPC: E04C2/32
Filed: 2013-07-22
Abstract: The invention relates to a bearing profile for false ceilings and walls and to an installation for making the same. According to the invention, the profile has a C- or U-shaped cross section, being made of zinc-plated sheet and having a medial base (A) and two sides (B) which can be flanged or not, having some longitudinal reinforcements (a) on the base (A), as folds of semi-rectangular, semi-trapezoidal or semi-circular cross section, some longitudinal reinforcements (a') on the sides (B) and at least one longitudinal row of long or short cross reinforcements (b, c, d and e) as parallel deep drawing recesses of rectangular cross section which can be straight or curved, with or without rounded corners, where positive and/or negative recesses alternate, at least in the area of the base (A) they being arranged between two longitudinal reinforcements (a), under an angle of 60...90° in relation with the edges. The claimed installation for making the bearing profile comprises a deep drawing device placed before a main profiling stand consisting of several profiling stands (3) having some profiled rollers (11 and 12), i.e. a lower one and an upper one, adjacent to some retaining rollers (13 and 14), i.e. a lower one and an upper one, each of them being placed on a corresponding shaft for profile interoperation by means of some spacing rings (15) and symmetrically rotated by means of some engaging gear wheels (16 and 17) placed on the shafts of the retaining rollers (13 and 14) which are fixed within some bearings (18) of a main stand support.
Patent AP-2000001821-A0 (AP)
Title: Formulations comprising dissolved paroxetine.
Inventor: GHAZAWI AHMAD
IPC: A61K31/4525
Filed: 1998-11-18
Abstract: Pharmaceutical formulations of paroxetine are provided in which the paroxetine is in solution in a solid, semi-solid or liquid carrier. The solutions are used to fill capsules, or self-supporting solid solutions are shaped into solid dosage forms such as tablets or pellets. Also disclosed are novel liquid formulations in which a solubilising agent is used to solubilise paroxetine in oils and/or lipids, and methods of avoiding other paroxetine forms converting to the hemihydrate, by use of anhydrous or hydrophobic carriers or excipients.
Patent IE-900675-A1 (IE)
Title: "A pharmaceutical composition"
Inventor: RYNNE ANDREW
IPC: A61K9/62
Filed: 1990-02-26
Abstract: A pharmaceutical product preferably in the form of a capsule comprises in one case Atenolol and Aspirin. A barrier film coating including a dihydric alcohol is provided around a tablet of Atenolol which in turn is surrounded by Aspirin inside a capsule. Aspirin is preferentially and maximally absorbed in the first hour after ingestion before significant release and absorbtion of Atenolol.
Patent MA-38385-A1 (MA)
Title: Nouvelle composition pour la stéatose hépatique non alcoolique (nafld)
Inventor: PATEL PANKAJ
IPC: A61P1/16
Filed: 2013-06-25
Abstract: La présente invention concerne un composé de formule (i) ou un produit pharmaceutique acceptable correspondant, où 'r' est décrit dans la description. De plus, l'invention concerne une composition comprenant une quantité thérapeutique efficace du composé de formule (i) et des procédés d'utilisation des composés pour traiter ou prévenir des troubles tels que la stéatose hépatique non alcoolique (nafld) comprenant le foie stéatosique (stéatose), la stéatohépatite non alcoolique (nash) et la cirrhose (cicatrisation avancée du foie).
Patent MA-38839-A1 (MA)
Title: Composés et compositions utiles comme inhibiteurs de mek
Inventor: BOCK MARK GARY
IPC: C07D471/04
Filed: 2014-08-14
Abstract: La présente invention concerne des composés de formule i dans laquelle n, r