Patent SG-11201807704W-A (SG)
Title: Composition and method of screening hydrocarbons to limit potential toxicological hazards
Inventor: OWENS TRACIE
IPC: G01N30/88
Filed: 2017-03-29
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111101110101111101111101111111111101111011111 International Bureau 0.. .1 j ..... ..or::,„, (10) International Publication Number (43) International Publication Date WO 2017/172867 Al 5 October 2017 (05.10.2017) IN I PO I P CT (51) International Patent Classification: (74) Agents: MIGLIORINI, Robert A. et al.; ExxonMobil Re- G01N 30/88 (2006.01) G01N 30/46 (2006.01) search and Engineering Company, 1545 Route 22 East, BOLD 53/30 (2006.01) P.O. Box 900, Annandale, NJ 08801-0900 (US). (21) International Application Number: (81) Designated States (unless otherwise indicated, for every PCT/US2017/024676 kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (22) International Filing Date: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, 29 March 2017 (29.03.2017) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (25) Filing Language: English HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (26) Publication Language: English MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (30) Priority Data: NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, 62/315,944 31 March 2016 (31.03.2016) US RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, 15/471,476 28 March 2017 (28.03.2017) US TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (71) Applicant: EXXONMOBIL RESEARCH AND ENGIN- EERING COMPANY [US/US]; 1545 Route 22 East, (84) Designated States (unless otherwise indicated, for every P.O. Box 900, Annandale, NJ 08801-0900 (US). kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (72) Inventors: OWENS, Tracie, L.; 1121 Nadine Street, Hou- TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, ston, TX 77009 (US). GOODING, Beatrice, M.; 106 TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, Stony Brook Road, Hopewell, NJ 08525 (US). WANG, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Frank, C.; 9 Cambridge Drive, Annandale, NJ 08801 LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, (US). SHUKLA, Yogi, V.; 7 Meadow Lane, Cherry Hill, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 645 Howard Aven- GW, KM, ML, MR, NE, SN, TD, TG). NJ 08003 (US). SANCHEZ, Eugenio; Jr., Charles, L.; 21 ue, Pitman, NJ 08071 (US). BAKER, Published: (US). SAEGER, Ro- Memel Drive, Thornton, PA 19373 Runnemede, NJ 08078 — with international search report (Art. 21(3)) land, B.; 207 West Evesham Road, (US). [Continued on next page] OF SCREENING HYDROCARBONS TO LIMIT POTENTIAL TOXICOLOGICAL (54) Title: COMPOSITION AND METHOD HAZARDS Fig. 1 10 \" 4\ . 500T a90T 7YOT —....„_ / 1 JJ 1 0 0 za .$0 40 b0 kw 71) sO so itiO liv Ir ----- V; 1st Dirnens un Retention Time (minutes) GC E \1 1 (57) : A method of screening a hydrocarbon stream for potential toxicological hazards. The method involves providing a I L — hydrocarbon stream; conducting 2-dimensional gas chromatography (2D-GC) analysis to quantify saturates and aromatic distribution 1-1 ---- in the hydrocarbon stream; identifying 2-8 ring aromatic distribution and weight percentage of 2-8 ring aromatic molecules in the N hydrocarbon stream from the 2D-GC analysis; relating the weight percentage of 2-8 ring aromatic molecules in the hydrocarbon C stream from the 2D-GC analysis to a mutagenicity index (MI), in which the MI is determined in accordance with ASTM Standard ei Method E 1687; and assessing a potential toxicological hazard of the hydrocarbon stream based on the weight percentage of 2-8 ring O aromatic molecules in the hydrocarbon stream from the 2D-GC analysis and a MI threshold value. The 2-8 ring aromatic distribution preferably includes 3-6 ring aromatics, more preferably 3.5-5.5 ring aromatics. The 2-8 ring aromatic distribution includes mono al- kylated and multi alkylated aromatic molecules. WO 2017/172867 Al 111111110111101110111111B11011101111111111HOEMICIIIIIIIIIIIII10111111 — before the expiration of the time limit for amending the claims and amendments to be (Rule republished 48.2(h)) in the event of receipt of