Patent SG-11201810465R-A (SG)
Title: Compositions and methods related to engineered fc constructs
Inventor: LANSING JONATHAN C
IPC: C07K16/28
Filed: 2017-05-23
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111011111111101 1111111101011111011010111100111111111110111111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/205436 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: RUTITZKY, Laura; 70 Clarendon Avenue, Somerville, C07K 16/28 (2006.01) C07K 16/46 (2006.01) Massachusetts 02144 (US). SCHULTES, Birgit C.; 12 (21) International Application Number: Monadnock Road, Arlington, Massachusetts 02476 (US). PCT/US2017/034087 (74) Agent: MEIKLEJOHN, PH.D., Anita L.; Fish & Richard- (22) International Filing Date: son P.C., P. 0. Box 1022, Minneapolis, Minnesota 55440-1022 (US). 23 May 2017 (23.05.2017) (25) Filing Language: English (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (26) Publication Language: English AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (30) Priority Data: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 62/340,322 23 May 2016 (23.05.2016) US DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, HN, 62/443,451 06 January 2017 (06.01.2017) US HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (71) Applicant: MOMENTA PHARMACEUTICALS, INC. MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, [US/US]; 675 West Kendall Street, Cambridge, Massachu- PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, setts 02142 (US). SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventors: LANSING, Jonathan C.; 220 Woburn Street, Reading, Massachusetts 01867 (US). BOSQUES, Car- (84) Designated States (unless otherwise indicated, for every _ los J.; 40 Brattle Street, Apt. 7, Arlington, Washington kind of regional protection available): ARIPO (BW, GH, 02476 (US). HUSTON, James S.; 270 Pleasant Street, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = #A206, Waterton, Massachusetts 02472 (US). LING, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, Leona E.; 45 Fells Road, Winchester, Massachusetts TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, = 01890 (US). MEADOR III, James; 38 Gryzboska Circle, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, — Framingham, Massachusetts 01702 (US). ORTIZ, Daniel; MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 15 High Street, Stoneham, Massachusetts 02180 (US). = = — (54) Title: COMPOSITIONS AND METHODS RELATED = = = 1200 = = = = — = = = • = T = :P. xte J TO ENGINEERED Platelet Levels a Day normst FC S mar CONSTRUCTS 1-1 .4 e en 7r kin ei IN 4\" st,\" FIG. 16 1-1 © (57) : The present disclosure relates to compositions and methods of engineered IgG Fc constructs, wherein the Fc constructs ei include one or more Fc domains. [Continued on next page] WO 2017/205436 Al MIDEDIMOMOIDEIROIDEMODIMIRINIMIMMOVOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(11)) — as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))