baber/WOPTO huggingface dataset:
Patent CA-2619457-C (CA)
Inventor: MEUTERMANS WIM
IPC: C07H15/12
Filed: 2006-10-03
Granted: 2016-09-06
Abstract: The invention provides a method of identifying biologically active compounds comprising: (a) designing a first library of compounds of formula (1) to scan molecular diversity wherein each compound of the library has at least two pharmacophoric groups R1 to R5 as defined below and wherein compound of the library has same number of pharmacophoric groups; (b) assaying the first library of compounds in one or more biological assay(s); and (c) designing a second library wherein each compound of the second library contains one or more additional pharmacophoric group with respect to the first library; such that the/each component of the first and second library is a compound of formula (1).
Patent CA-2626808-C (CA)
Inventor: CHING JESUS
IPC: C12M3/00
Filed: 2006-10-18
Granted: 2016-02-02
Abstract: A cassette for preparing a sample includes a mixing chamber to receive a sample of cells, a holding chamber and an enzyme in the holding chamber The enzyme is transferable into a mixing chamber to break the cells and release nucleic acid from the cells to create bulk material and the nucleic acid in the bulk material A second holding chamber has magnetic particles, the magnetic particles being transferable to the mixing chamber to bind with the nucleic acid, and a magnet to attract the magnetic particle with the nucleic acid, and to separate the nucleic acid from the bulk material in the mixing chamber.
Patent CA-2628002-C (CA)
Inventor: BLACK RICHARD L
IPC: H05B39/04
Filed: 2002-07-03
Granted: 2012-06-12
Abstract: An apparatus in an electronic control system allows two or three wire operations. A power supply (150) can supply power to the enclosed circuity in both two and three wire installations. Two separate zero cross detectors are used such that timing information can be collected in both two or three wire installations. Both zero cross detectors (110) are monitored and are used to automatically configure the electronic control. Over voltage circuity senses an over voltage condition across a MOSFET which is in the off state and turns the MOSFET on so that it desirably will not reach the avalanche region. Over current circuity senses when the current through the MOSFET's has exceeded a predetermined current threshold and then turns the MOSFETs off so they do not exceed the MOSFETs' safe operating area (SOA) curve. Latching circuity (120) is employed to keep the protection circuity in effect even after a fault condition has cleared. Lockout circuity (130) is used to prevent one protection circuit from tripping after the other circuit has already tripped from a fault condition. The protection circuity output is desirably configured such that it can bypass and override the normal turn on and turn off impedance and act virtually directly on the gates of the MOSFETs. Preferably, the system has a high effiiciency switching type power supply in parallel with a low frequency controllably conductive device.
Patent CA-2628954-C (CA)
Inventor: POMPEJUS MARKUS
IPC: C12P13/08
Filed: 2006-11-27
Granted: 2015-08-18
Abstract: The invention relates to a method for producing by fermentation at least one type of organic compound containing at least 3 C atoms or at least two C atoms and at least one N atom consisting a1) in grinding a starch source for obtaining a ground product containing at least one part of solid starch-devoid components of the starch source, 2a) in suspending the ground material in an aqueous fluid and in hydrolysing by enzimatically liquefying the starch part of the starch source and eventually metabolisable metabolisable subsequently saccharifying, thereby obtaining a first mono- and oligosaccharide-containing liquid (1), b) in adding, under fermentation conditions, the mono- and oligosaccharide-containing liquid (1) together with monosaccharides, disaccharides and/or metabolisable oligosaccharides or with a monosaccharides, disaccharides and/or metabolisable oligosaccharides-containing composition at a concentration less than 50 % by weight which is practically devoid of water insoluble solids, to a fermentation medium containing a micro organism which enables an organic compound to be overproduced.
Patent CA-2629001-C (CA)
Inventor: CHRISTENSEN CAROLINE WEST
IPC: A41C1/08
Filed: 2008-04-14
Granted: 2016-01-19
Abstract: Un système de support comprend : une bande abdominale pour supporter un poids de l'abdomen d'un utilisateur, la bande abdominale adaptée pour entourer une partie inférieure de l'abdomen et des hanches et reposant sur le bas du dos de l'utilisateur; une paire de bretelles, chaque bretelle adaptée pour passer sur un épaulement respectif de l'utilisateur et se fixer avec la bande abdominale sur une antérieure de l'utilisateur et sur une postérieure de l'utilisateur; et une paire de bandes d'arêtes, chaque bande de l'aine adaptée pour passer sous un entrejambe de l'utilisateur et la fixation de la bande sur une abdominale antérieure de l'utilisateur et sur une postérieure de l'utilisateur. Un procédé d'utilisation et de fabrication pour un autre procédé sont fournis.
Patent CA-2634468-C (CA)
Title: Spiroketals
Inventor: REDDELL PAUL WARREN
IPC: A61P33/02
Filed: 2006-12-22
Granted: 2014-10-07
Abstract: The present invention relates to spiroketal compounds, such as those of formula II, that are useful in methods of treating or preventing protozoal infections, parasitic infections, bacterial infections, cell proliferative disorders and anti inflammatory disorders. The sprioketal compounds are also useful as immunosuppressive agents, also in methods of controlling pests. (see formula II)
Patent CA-2636662-C (CA)
Inventor: FINLEY JAMES J
IPC: C23C14/00
Filed: 2007-01-17
Granted: 2011-08-16
Abstract: A method is provided for producing particles, such as nanoparticles. The method includes introducing an ionic liquid into a deposition chamber, and directing one or more material toward or depositing one or more materials onto the ionic liquid by physical vapor deposition to form nanoparticles in the ionic liquid.
Patent CA-2641451-C (CA)
Title: Polymer formulations of cetp inhibitors
Inventor: GEERS SARAH
IPC: A61K9/16
Filed: 2007-02-09
Granted: 2012-10-02
Abstract: A pharmaceutical composition comprises (a) a CETP inhibiting compound, or a pharmaceutically acceptable salt thereof; (b) a concentration-enhancing polymer; and (c) optionally one or more surfactants; wherein the compound has the structure shown as Formula I below. The composition raises HDL-cholesterol and lowers LDL-cholesterol.
Patent CA-2643162-C (CA)
Inventor: VENKATARAMAN GANESH
IPC: G06F19/00
Filed: 2000-04-24
Granted: 2018-01-02
Abstract: A data structure, tangibly embodied in a computer computer-readable medium, representing a polymer of chemical units is disclosed. The data structure includes an identifier including a plurality of fields for storing values corresponding to properties of the polymer. In one embodiment, the fields are capable of storing binary values. The polymer may, for example, be a polysaccharide and the chemical units may be saccharides. A computer-implemented method for determining whether properties of a query sequence of chemical units match properties of a polymer of chemical units. The query sequence is represented by a first data structure, tangibly embodied in a computer-readable medium, including an identifier including a plurality of bit fields for storing values corresponding to properties of the query sequence. The polymer is represented by a second data structure, tangibly embodied in a computer-readable medium, including an identifier including a plurality of bit fields for storing values corresponding to properties of the polymer. The invention also relates to methods of sequencing polymers such as nucleic acids, polypeptides and polysaccharides and methods for identifying a polysaccharide-protein interaction. The invention also involves a notational system referred to as Property Encoded Nomenclature.
Patent CA-2646341-C (CA)
Inventor: O'KEEFFE ERIC
IPC: B07B1/42
Filed: 2007-03-14
Granted: 2015-04-21
Abstract: A screening apparatus having a screening box movably mounted on a support member (22) via biasing members (23), the screening box having a pair of opposing side walls (14, 15) and a vibrating arrangement (100) for vibrating the screening box relative to the support member(22). The vibrating arrangement (100) comprising a shaft housing member (42) for housing at least one rotatable shaft (1, 2, 3) and shaft coupling members (41) for coupling the shaft housing member (42) to the opposing side walls (14, 15) of the screening box. A shaft (1, 2, 3) is rotatably housed in the shaft housing member (42). The vibrating arrangement (100) further comprising a throw generating assembly (53) rotatably mounted on both ends of the shaft housing member (42). The throw generating assembly (53) is releasably fixed to the shaft (1, 2, 3). A drive arrangement is also provided comprising a motor (60), shaft driver members (4, 5, 6) on one end of the shaft (1, 2, 3) and a flexible endless drive member (7) coupled between the motor (60) and the shaft driver members (4, 5, 6). Each throw generating assembly (53) is rotatable about the shaft housing member (42) via the drive arrangement and shaft (1, 2, 3) to impart vibratory movement to the screening box.
Patent CA-2648470-C (CA)
Inventor: TURNER MICHAEL D
IPC: C08L23/04
Filed: 2007-04-03
Granted: 2014-09-16
Abstract: La présente invention concerne des compositions destinées à des applications de moulage par extrusion-soufflage et autres applications. Lesdites compositions comprennent un interpolymère de l'éthylène à haut poids moléculaire et un polymère de l'éthylène à bas poids moléculaire, ledit interpolymère à haut poids moléculaire ayant une densité de 0,920 g/cm3 à 0,950 g/cm3 et un I2I de 0,05 à 1 dg/min et ledit polymère à bas poids moléculaire ayant une densité de 0,965 g/cm3 à 0,985 g/cm3 et un I2 de 600 à 2000 dg/min. Les compositions ont une densité allant de 0,950 g/cm3 à 0,970 g/cm3 et elles comprennent de 45 à 80 % en poids du composant à haut poids moléculaire et de 20 à 55 % en poids du composant à bas poids moléculaire, en se basant sur le poids total de ces deux composants. L'invention concerne également des procédés de préparation desdites compositions ainsi que des articles fabriqués à partir de ces compositions.
Patent CA-2650295-C (CA)
Title: Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
Inventor: CASTANEDO GEORGETTE
IPC: C07D491/04
Filed: 2007-04-24
Granted: 2015-12-29
Abstract: Compounds of Formulas (Ia) and (Ib), and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula (Ia) and (Ib) for in vitro, in situ, and in vivodiagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Patent CA-2650428-C (CA)
Inventor: LEE SEUNG HYUNG
IPC: C08L23/06
Filed: 2007-04-20
Granted: 2012-05-15
Abstract: The present invention relates to a tree resistant, cross- linkable polyolefin resin composition for insulation capable of improving electric properties of an insulator of the high voltage power cable and thus improving a long-life stability of an underground distribution cable as having a more superior resistance to water tree deterioration caused by moisture, superior thermal-oxidative stability, superior scorch resistance when extruding as well as obtaining a proper cross- linking degree when cross-linking.
Patent CA-2659959-C (CA)
Title: Systeme et procede pour une gestion de cles sur des systemes de communication sans fil
Inventor: NARAYANAN VIDYA
IPC: H04L29/06
Filed: 2007-08-24
Granted: 2013-04-23
Abstract: L'invention concerne une approche originale de gestion de clés pour sécuriser des transferts intercellulaires de communication entre un terminal d'accès et deux points d'accès. Cette approche permet le transfert intercellulaire sécurisé de communications entre un terminal d'accès et un point d'accès sans risquer d'exposer une clé maîtresse pour le terminal d'accès. Des clés maîtresses temporaires sont déduites pour des transferts intercellulaires de latence faible et une authentification sécurisée entre un nouveau point d'accès et le terminal d'accès. Dans un aspect, un plan distributif de gestion de clés est obtenu dans lequel un point d'accès actuel génère une nouvelle clé de sécurité (sur la base de sa propre clé de sécurité) qui est utilisée par le point d'accès suivant avec lequel un terminal d'accès communique. Dans un autre aspect, un plan centralisé de gestion de clés est obtenu dans lequel un dispositif d'authentification central maintient, génère et distribue de nouvelles clés de sécurité (sur la base d'une clé de sécurité maîtresse associée au terminal d'accès) à des points d'accès.
Patent CA-2662871-C (CA)
Inventor: LUM OOI LIN
IPC: C12M1/12
Filed: 2005-10-06
Granted: 2014-03-25
Abstract: The present invention relates to a process for recovery and purification of lactic acid from a fermentation broth containing lactic acid. The process comprises subjecting the fermentation broth to ultralfiltration and/or microfiltration to form a first permeate, concentrating the first permeate to form concentrated broth, subjecting the concentrated broth to supported liquid membrane for extraction of lactic acid into a separate stream, subjecting the extracted lactic acid solution to activated carbon for removal of colour, subjecting the extracted lactic acid solution to cation exchange resin for deminerization, subjecting the extracted lactic acid solution to anion exchange resin for removal of anionic impurities and concentrating the extracted lactic acid solution to desired concentration. The supported liquid membrane of the present invention contains an organic layer that comprises a earner, a co-extractant, a diluent and a stabilizer.
Patent CA-2665044-C (CA)
Title: Systeme de couches avec au moins une couche de cristal mixte d'un oxyde multiple
Inventor: RAMM JURGEN
IPC: C23C14/08
Filed: 2007-09-03
Granted: 2016-08-23
Abstract: L'invention concerne un système de couches de type PVD destiné à enduire des pièces usinées comprenant au moins une couche de cristal mixte d'un oxyde multiple avec la composition suivante : (Me11-xMe2x)2O3. Me1 et Me2 sont alors chacun au moins un des éléments Al, Cr, Fe, Li, Mg, Mn, Nb, Ti, Sb ou V. Les éléments de Me1 et Me2 sont chacun différents. Le réseau cristallin de la couche de cristal mixte dans le système de couches de type PVD présente une structure de type corindon, qui est caractérisée, dans un spectre de la couche de cristal mixte mesuré par diffractométrie des rayons X, par au moins trois des lignes attribuables à la structure de type corindon. L'invention décrit en outre un procédé de revêtement sous vide destiné à la fabrication d'une couche de cristal mixte d'un oxyde multiple ainsi que les outils et pièces détachées enduits correspondants.
Patent CA-2667577-C (CA)
Inventor: YOUNG MICHAEL
IPC: G06Q10/08
Filed: 2007-10-24
Granted: 2017-11-07
Abstract: Un serveur d'exploration permet de suivre un objet dans une chaîne d'approvisionnement conformément à une pluralité d'événements prédéfinis. L'objet est identifiable par un identifiant d'objet. Le serveur d'exploration comprend les éléments suivants : une interface de communication configurée pour communiquer avec chacun d'une pluralité de partenaires dans la chaîne d'approvisionnement en utilisant un protocole prédéfini ; une mémoire de données configurée pour stocker des événements pour l'objet, les événements étant reçus de la pluralité de partenaires. Chaque événement stocké dans la mémoire de données possède un identifiant d'objet, une étape du cycle de vie, un identifiant de partenaire et un identifiant de temporisation. Egalement, un processeur est configuré pour chercher la mémoire de données en réponse à une demande de renseignement concernant l'objet.
Patent CA-2668310-C (CA)
Inventor: TSURUTA ORIHIRO
IPC: B65B9/20
Filed: 2005-03-22
Granted: 2010-10-26
Abstract: A packaging bag manufacturing method is providing for introducing a filler into a cylindrical film from a lower end of an introduction nozzle, and thermally sealing the cylindrical film, into which the filler has been introduced, in a width direction thereof, thereby manufacturing a packaging bag in which the filler is sealed. The method comprises: (a) sandwiching the cylindrical film together with a lower end periphery of said introduction nozzle using a pair of members disposed in opposition to each other across the cylindrical film, while an area of the cylindrical film to be thermally sealed is positioned substantially above said pair of members; (b) introducing the filler from the lower end of said introduction nozzle while the cylindrical film is nipped by said pair of members; (c) carrying the cylindrical film until the area to be thermally sealed is positioned below said pair of members after the introduction of the filler; and (d) thermally sealing the part to be thermally sealed in a width direction of the cylindrical film after carrying the cylindrical film.
Patent CA-2674797-C (CA)
Title: Psychotherapeutic device
Inventor: LEE IN TAE
IPC: A61H5/00
Filed: 2009-01-21
Granted: 2012-10-30
Abstract: Disclosed herein is a psychotherapeutic device which induces saccadic eye movement Of a user in a certain way, thus increasing the efficacy of psychiatric treatment for the user. The psychotherapeutic device in accordance with the present invention includes a main body including a frame having an opened portion corresponding to a user's eyes, a support means for placing the frame on the user's face, and a front panel connected to a front surface of the frame and providing light spots moved left and right with respect to the user's eyes; and a control box for controlling the operation of the front panel, wherein the main body and the control box are electrically connected to each other by a wire.
Patent CA-2675098-C (CA)
Title: Film supply apparatus and filling and packaging system including the film supply apparatus
Inventor: TSURUTA ORIHIRO
IPC: B31B50/64
Filed: 2007-01-16
Granted: 2013-04-09
Abstract: Film supply apparatus (2) has two film holders (22a, 22b) supporting two rolls of film as film (101) on a use side and film (100) on a stand-by side respectively, feed rollers (3) for feeding film (101) on the use side, film holding member (34) holding a leading end portion of film (100) on the stand-by side, sucker (36) pulling back film (100) on the stand-by side upstream in a feeding direction and heater bar (31) heat-sealing two films (100, 101). Sucker (36) attracts film (100) by suctioning and pulls film (100) back to a position where a leading end portion thereof faces heater bar (31).
Patent CA-2679600-C (CA)
Title: Radio receiver having a multi-state variable threshold automatic gain control (agc) for fast channel scanning acquisition and method for using same
Inventor: RUELKE CHARLES R
IPC: H04B7/26
Filed: 2008-03-11
Granted: 2012-07-10
Abstract: A radio receiver (300) having a multi-state variable threshold automatic gain control (AGC) for fast channel scanning acquisition includes an amplifier (303) having an automatic gain control (AGC) for controlling the gain of a receiver analog signal. An analog-to-digital converter (ADC) (311) is used for converting the receiving analog signal to a digital signal while a digital signal processor (DSP) (325) operates to process the digital signal. A signal magnitude estimator (315) in an AGC controller (313) provides a signal strength estimate of the received signal. The AGC controller (313 ) then sets the receiver amplifier (303) for an open-loop AGC operational mode and sets a first threshold for triggering an interrupt service request (ISR). This ISR is provided the DSP (325) and the host processor (327) if a radio frequency (RF) signal is detected above a first threshold during a priority scan of a priority channel to minimize interruptions in audio during priority scan.
Patent CA-2683195-C (CA)
Title: Sels monochlorhydrates d'un inhibiteur d'histone desacetylase
Inventor: DICKENS JULIUS W J
IPC: C07D211/26
Filed: 2008-05-13
Granted: 2016-08-09
Abstract: Cette invention porte sur de nouvelles formes cristallines de sels mono-HCl et d'un hydrate du sel mono-HCl de JNJ-26481585, un inhibiteur d'histones désacétylases. L'invention porte également sur des procédés de fabrication de ces formes, sur des intermédiaires utilisés dans ces procédés, sur des compositions pharmaceutiques comprenant ces formes, et sur l'utilisation de ces formes dans un traitement médical, par exemple, en tant que médicament pour inhiber des états prolifératifs, tels que le cancer et la leucémie.
Patent CA-2685404-C (CA)
Inventor: BUCHET PHILIPPE
IPC: C21D1/34
Filed: 2008-05-20
Granted: 2015-06-30
Abstract: The invention pertains to the heating of a metal strip, and relates to equipment for heating a metal strip that comprises a pre-heating housing (2) provided with a device (11) for projecting hot gases towards the strip (1), a heating housing (4)with regenerative burners (16, 16'), a duct (31) for discharging the gases from the heating housing, a three-way adjustable valve (32) and an adjustment device including a sensor (34) for detecting the setpoint temperature of the metal strip and a member (36) for adjusting the three-way valve (32) so that it can adjust the amount of hot gases fed to the projection device (11). The invention can be used in equipment for heating narrow strips before annealing the same.
Patent CA-2685554-C (CA)
Inventor: SOMASUNDARAM SHANKAR
IPC: H04W36/18
Filed: 2008-04-23
Granted: 2016-07-12
Abstract: The method and apparatus disclosed are used for handling RL and handover failures based on context transfer details and RACH procedures that enhance the failure handling procedures. After an RL failure, a user equipment (UE) includes the identity of an evolved Node-B (eNodeB) and/or cell as an information element (IE) in an RRC connection request and/or a cell update message or any other RRC message along with a UE identity.
Patent CA-2693081-C (CA)
Title: Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique
Inventor: LO YUK-MING DENNIS
IPC: G06F19/18
Filed: 2008-07-23
Granted: 2016-01-26
Abstract: Cette invention, selon des modes de réalisation, porte sur des procédés, des systèmes et un appareil pour déterminer si une aneuploïdie chromosomique foetale existe à partir d'un échantillon biologique obtenu auprès d'une femme enceinte. Des molécules d'acide nucléique de l'échantillon biologique sont séquencées, de telle sorte qu'une fraction du génome est séquencée. Des quantités respectives d'un chromosome cliniquement pertinent et de chromosomes de fond sont déterminées à partir des résultats du séquençage. Un paramètre issu de ces quantités (par exemple, un rapport) est comparé à une ou à plusieurs valeurs limites, permettant ainsi de déterminer une classification quant à l'existence d'une aneuploïdie chromosomique ftale.
Patent CA-2698505-C (CA)
Inventor: CHEN KEN-CHING
IPC: A47B88/49
Filed: 2010-03-31
Granted: 2012-05-29
Abstract: An opening device for a slide assembly includes a swing member with a pin portion, a first resilient member and a pusher connected to the first rail. The first resilient member applies a force to the pusher. An engaging member pivotably connected to the second rail and includes a block and a positioning leg contacting a portion of the second rail. The engaging member is connected to a second resilient member. When the second rail is retracted relative to the first rail, the block of the engaging member contacts the pin portion of the swing member. When a pull force is applied to the retracted second rail, the engaging member swings an angle on the second rail to disengage the block from the pin portion of the swing member, and the engaging member returns to its original position relative to the second rail.