baber/WOPTO huggingface dataset:
Patent WO-2019010232-A1 (WO)
Title: Multiple probe ablation planning
Inventor: DESAI DEVASHREE S
IPC: A61B18/02
Filed: 2018-07-03
Abstract: A method of performing a percutaneous multi-probe treatment includes: acquiring a scan image of an object to be treated with multi-probe percutaneous insertions; determining a first point in a region of interest in the scan image; determining a second point at a surface of the object in the scan image; generating a reference trajectory by connecting the first point and the second point; arranging, around the first point, a number of third points corresponding to tips of probes to be inserted into the object; generating planned insertion trajectories for the probes based on the number of probes to be inserted and the reference trajectory; and causing a monitor to display superposed on the scan image, at least one of the planned insertion trajectories. The planned insertion trajectories extend in a geometric relationship to the reference trajectory and pass through the third points and through one or more second points.
Patent WO-2019036131-A1 (WO)
Title: A grounded filter regulator lubricator
Inventor: RAWAL MANOJ MOHAN
IPC: H01R4/48
Filed: 2018-07-16
Abstract: A grounded FRL for treating a pressurized air supply has a housing with a connecting mechanism for connecting to a collector bowl. The collector bowl is made from a metal base material and has an open end with a connecting mechanism and a closed distal end. The housing has a flange that is electrically conductive and extending downwardly at an exterior of the bowl. At least one grounding clip member is made from electrically conductive material and has an exterior mounting end attached to the flange for electrical connectivity thereto and has a radially inner end that electrically makes contact with the metal base materials of the collector bowl and the housing.
Patent WO-2019018394-A1 (WO)
Title: Treating rheumatoid arthritis
Inventor: HO I-CHENG
IPC: G01N33/53
Filed: 2018-07-17
Abstract: The disclosure relates to biomarkers of rheumatoid arthritis, e.g., PTPN22, PFKFB3, ATM, IL-17A, and IL-17F, and methods of using these biomarkers for selecting an effective treatment for rheumatoid arthritis.
Patent WO-2019032579-A1 (WO)
Title: Fluid control system and method
Inventor: LE TUAN
IPC: E03D1/14
Filed: 2018-08-07
Abstract: Some embodiments include a fluid control system with an outlet valve assembly, an inlet valve assembly including a venturi inlet valve, and an actuator coupled to the inlet valve assembly. In some embodiments, the actuator can enable a user to control a flush volume of fluid control system. Some embodiments include a moveable float positioned in a chamber of the outlet valve assembly, where the chamber includes a variably-sized upper portion with a volume that is based at least in part on a variable position of the moveable float in the chamber. Some embodiments include a adjustable control valves coupled to an outer surface of the outlet valve assembly and the inlet valve assembly. Some embodiments also include a bellows positioned in and coupled to the variably-sized upper portion. In some embodiments, the bellows are fluidly coupled to the venturi inlet valve and at least one of the control valves.
Patent WO-2019032921-A1 (WO)
Title: An anti-apoptotic function of pkm2 and intracellularly expressed scfv antibodies
Inventor: NEWMEYER DONALD
IPC: C12N15/66
Filed: 2018-08-09
Abstract: This application generally relates to the field of methods, systems and compositions for addressing diseases associated with apoptotic cell death, including autoimmune diseases and inflammatory diseases, and more particularly to such methods, systems and compositions that use antibodies having binding specificity to PKM2.
Patent WO-2019032934-A1 (WO)
Title: Reconstitution device, system, and method to administer a drug in a moderate bolus
Inventor: DESBROSSES FREDDY
IPC: A61J1/20
Filed: 2018-08-10
Abstract: A reconstitution device includes: a piercing member (30) having a first end (32) and a second end (34), the first end of the piercing member configured to engage an administration port; a delivery member (40) having a first end (42) and a second end (44), the first end of the delivery member configured to engage a delivery site; a collar (20) configured to engage a vial (25); and a cap (22) extending from the collar (20) and holding the piercing member (30) and the delivery member (40) such that the second end (34) of the piercing member and the second end (44) of the delivery member are disposed within the cylindrical collar (20).
Patent WO-2019050658-A1 (WO)
Title: Fluidic pump and latch gate
Inventor: Ochs Garett Andrew
IPC: G06F3/01
Filed: 2018-08-13
Abstract: A fluidic device comprises a first channel conduit, a valve apparatus, and an additional element adjacent to the first channel conduit. The first channel conduit transports fluid from a first fluid entrance to a fluid exit. In one embodiment, the additional element is a pump chamber that receives fluid from a second fluid entrance and pumps fluid into the first channel conduit in accordance with fluid pressure. Alternatively, the additional elements include a second channel conduit and a neck of the first channel conduit. The first channel conduit and the second channel conduit share a common wall. Fluid pressure in the first channel conduit controls a valve apparatus. The value apparatus controls a rate of fluid flow in the first channel conduit by deforming the common wall to change a cross-sectional area of the neck, which changes a rate of fluid flow in the second channel conduit.
Patent WO-2019040371-A1 (WO)
Title: Power optimization through orchestration and prioritization of machines and functions
Inventor: LEWIS MICHAEL
IPC: G06F1/26
Filed: 2018-08-20
Abstract: Systems and methods are provided for managing power usage in mining environments. The amount of power needed to operate a set of electrical machines that are to run simultaneously is determined. Power usage by the electrical machines during a time period can be predicted based on how much power is expected to be needed by each machine. If the predicted power usage exceeds a threshold power usage, power to one or more electrical machines in the mining environment is restricted so that actual power usage in the mining environment does not exceed the threshold power usage during the specified time period. The electrical machines which will have power restricted thereto can be selected based at least in part on relative priorities for the electrical machines in the set. Power can be restricted to machines as a whole (an effective shutdown), or to specific operations of the machines.
Patent WO-2019046202-A1 (WO)
Title: Systems and methods for instrument disinfection and anti-microbial coating
Inventor: Sharp Gregory
IPC: A61L2/07
Filed: 2018-08-27
Abstract: A disinfection chamber may be configured for receiving a disinfecting vapor from a vapor source and channeling it to contact a surface of an instrument within the chamber. The vapor source may provide the vapor to the disinfecting chamber via an inlet in a chamber cover of the chamber. A vapor core within the disinfecting chamber may channel the vapor from the inlet through a length of the vapor core. A portion of the vapor may pass from an interior of the vapor core and contact the surface of the instrument. When the vapor contacts the surface, the vapor may disinfect the surface, and may deposit an anti-microbial film on the surface.
Patent WO-2019046496-A1 (WO)
Title: Cyclic dinucleotides as anticancer agents
Inventor: HARIKRISHNAN LALGUDI S
IPC: A61P35/00
Filed: 2018-08-30
Abstract: The present invention is directed to compounds of the formula (I) wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.
Patent WO-2019046505-A1 (WO)
Title: Method and apparatus for providing unicast representations within a broadcast coverage area
Inventor: PRATURI UPENDRA
IPC: H04W76/40
Filed: 2018-08-30
Abstract: An apparatus may be configured to receive a segment manifest and an indication of available content accessible through a MBMS service. In an aspect, the available content may include a first set of representations available in a broadcast coverage area, and a second set of representations and a third set of representations available in a unicast coverage area. The apparatus may be located within the broadcast coverage area and the unicast coverage area and elect to receive at least a component of the available content through the third set. Moreover, the apparatus may be further configured to receive at least the component of the available content through the third set of representations, via a unicast channel, based on which of the first set, the second set and the third set of representations are elected to be received.
Patent WO-2019074647-A1 (WO)
Title: Antiperspirant stick compositions
Inventor: MIKKELSEN TYLER
IPC: A61K8/92
Filed: 2018-09-21
Abstract: An antiperspirant stick composition can include a synthetic wax having a viscosity of from about 0.1 centipoise (cps) to about 20 cps at a temperature of 99 °C, a hydrophilic surfactant having a hydrophilic-lipophilic balance (HLB) value greater than 10, a plasticizer present in an amount sufficient to minimize hardening of the composition due to contact with an aqueous composition, and an effective amount of an antiperspirant active agent. The hydrophilic surfactant can be present in an amount sufficient to minimize perspiration-induced discoloration of fabric in contact with the composition.
Patent WO-2019074841-A1 (WO)
Title: Type i-e crispr-cas systems for eukaryotic genome editing
Inventor: GASIOR STEPHEN LAWRENCE
IPC: C12N15/82
Filed: 2018-10-08
Abstract: ABSTRACT Compositions and methods are provided for modification of a target sequence in the genome of a cell. The methods and compositions employ a cascade system and guide polynucleotide to provide an effective system for targeting, binding to, and modifying or altering target sequences within the genome of a cell or organism. Also provided are systems further comprising an endonuclease. Compositions and methods are also provided for guide polynucleotide/endonuclease systems comprising at least one nuclease covalently or non-covalently linked to, or assembled with, at least one protein subunit of a cascade, and for compositions and methods for direct delivery of endonucleases.
Patent WO-2019084222-A1 (WO)
Inventor: CARRERA CONTRERAS OLIVER
IPC: B60H1/34
Filed: 2018-10-25
Abstract: La présente invention concerne une bouche d'aération (10) pour un véhicule comprenant un conduit d'air (14) qui est délimité au moyen d'un boîtier (12), comprenant en outre un élément d'actionnement (16) et au moins un élément de régulation de flux d'air (20, 20') qui peut être réglé au moyen de l'élément d'actionnement (16), dans laquelle il est possible qu'un flux d'air qui s'écoule à travers le conduit d'air (14) le long d'une direction d'écoulement principale soit influencé au moyen d'un réglage de l'au moins un élément de régulation de flux d'air (20, 20'), un élément d'amortissement (18) agissant sur l'élément d'actionnement (16), l'élément d'amortissement (18) étant précontraint dans une position de contact sur l'élément d'actionnement (16).
Patent WO-2019089558-A1 (WO)
Title: Graphical user interfaces for determining personalized endocannabinoid genotypes and associated recommendations
Inventor: MAY LEN
IPC: C12Q1/686
Filed: 2018-10-30
Abstract: An example embodiment may involve (i) receiving, by a server device, deoxyribonucleic acid (DNA) information associated with a user; (ii) parsing, by the server device, the DNA information to identify one or more single nucleotide polymorphisms (SNPs)- (iii) determining, by the server device and based, on the identified SNPs, an endocannabinoid genotype of the user; (iv) determining, based on the endocannabinoid genotype of the user, a recommendation of one or more cannabinoid formulations; (v) transmitting, to a client device associated with the user, a web-based representation of a first graphical user interface; and (vi) receiving, from the client device, an indication to display a detailed representation of a particular cannabinoid formulation of the one or more cannabinoid formulations.
Patent WO-2019094505-A1 (WO)
Title: Laser à cavité verticale et à émission par la surface à rétroaction polarisée
Inventor: WESTBERGH PETTER
IPC: H01S5/20
Filed: 2018-11-07
Abstract: L'invention concerne un VCSEL qui peut comprendre un miroir DBR inférieur et un miroir DBR supérieur au-dessus du miroir DBR inférieur. Le VCSEL peut comprendre une cavité optique verticale située à l'intérieur d'une partie des miroirs DBR inférieur et supérieur. La cavité optique verticale peut être configurée pour émettre un signal optique. Le VCSEL peut comprendre une cavité optique de rétroaction latérale située à l'intérieur d'une partie différente du fond et les miroirs DBR supérieurs étant configurés pour recevoir un signal de polarisation de rétroaction configuré pour polariser la cavité optique de rétroaction latérale pour ajuster le signal optique. Le VCSEL peut comprendre une région active formée entre le fond et les miroirs DBR supérieurs qui peuvent comprendre une couche d'oxyde définissant une ouverture d'oxyde. Le VCSEL peut comprendre un implant d'isolation configuré pour isoler électriquement la cavité optique verticale de la cavité optique de rétroaction et pour créer une première et une seconde ouverture à l'intérieur de l'ouverture d'oxyde.
Patent WO-2020060578-A1 (WO)
Inventor: PENDSE RAJENDRA D
IPC: H01L23/13
Filed: 2018-12-19
Abstract: An assembly of circuit dies is stacked through oxide-oxide bonding. The assembly includes a silicon substrate, in which a plurality of through-silicon-vias are formed. The silicon substrate is attached onto a die through dielectric-dielectric bonding with at least part of the through-silicon-vias electrically connected to the die. The silicon substrate and die are attached onto another die through oxide-oxide bonding. Then the through-silicon-vias are revealed. The silicon substrate functions as a carrier substrate before the revealing. The silicon substrate and two dies can be attached to a printed circuit board, which is electrically connected to the two dies. One or more electrical components can be attached onto the silicon substrate and electrically connected to the die through the through-silicon-vias. The silicon substrate may include a metal element for diffusing heat generated from operation of the one or more electrical components.
Patent WO-2019140214-A1 (WO)
Title: Robotic surgical control system
Inventor: BONO PETER
IPC: A61B34/00
Filed: 2019-01-11
Abstract: The invention involves a system and method for controlling the movements of a multi-axis robot to perform a surgery at least on the spinal area of a human in vivo. The system includes controls and software coding to cause the robot to move in desired patterns to complete the surgery, which may include bone, disc and tissue removal, and may also include insertion of hardware for fusing adjacent bony structures.
Patent WO-2019147465-A1 (WO)
Title: High severity fluidized catalytic cracking systems and processes for producing olefins from petroleum feeds
Inventor: BOURANE ABDENNOUR
IPC: C10G11/18
Filed: 2019-01-17
Abstract: Systems and processes are disclosed for producing petrochemical products, such as ethylene, propene and other olefins from crude oil in high severity fluid catalytic cracking (HSFCC) units. Processes include separating a crude oil into a light fraction and a heavy fraction, cracking the light fraction and heavy fraction in separation cracking reaction zones, and regenerating the cracking catalysts in a two-zone regenerator having a first regeneration zone for the first catalyst (heavy fraction) and a second regeneration zone for the second catalyst (light fraction) separate from the first regeneration zone. Flue gas from the first catalyst regeneration zone is passed to the second regeneration zone to provide additional heat to raise the temperature of the second catalyst of the light fraction side. The disclosed systems and processes enable different catalysts and operating conditions to be utilized for the light fraction and the heavy fraction of a crude oil feed.
Patent WO-2019147660-A1 (WO)
Title: Method of enhancing seed germination under abiotic stress with chitin oligosaccharides
Inventor: HABIB AHSAN
IPC: C12N1/20
Filed: 2019-01-23
Abstract: The present disclosure provides methods of enhancing abiotic stress tolerance in plants and plant propagation materials. In some embodiments, the method comprises applying at least one chitin oligosaccharide to the plant or plant propagation material in an amount effective to enhance its cold tolerance, heat tolerance, drought tolerance, pH tolerance and/or salt tolerance.
Patent WO-2019152260-A1 (WO)
Title: Database system
Inventor: VASWANI KAPIL
IPC: G06F21/57
Filed: 2019-01-25
Abstract: In various examples, there is a database system which comprises an operating system, a query engine, a transaction manager and components implementing database administration functionality. The query engine and the transaction manager are configured to be executed within one or more memory enclaves of a host computer system separately from the operating system and the components implementing database administration functionality.
Patent WO-2019148206-A1 (WO)
Title: Crispr effector system based diagnostics
Inventor: ZHANG FENG
IPC: C12N15/10
Filed: 2019-01-29
Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences, and includes detection by colorimetric and/or fluorescence shifts. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.
Patent WO-2019165396-A1 (WO)
Title: Hot melt pressure sensitive adhesive compositions and methods of making the same
Inventor: QIN DERRICK
IPC: C08K5/00
Filed: 2019-02-26
Abstract: A hot melt pressure sensitive adhesive composition comprising an isocyanate-group terminated compound; a plasticizer; a thermoplastic polymer; and a tackifying agent. At least one of the plasticizer or tackifying agent is hydroxyl modified.
Patent WO-2019165442-A1 (WO)
Title: Acid labile surfactants and method for performing protein solubilization or enzyme digestion
Inventor: BROUSMICHE DARRYL
IPC: G01N30/02
Filed: 2019-02-26
Abstract: This invention relates to an acid labile surfactant. In particular, the surfactants of the present invention include a dioxolane or dioxane functional group which enables the surfactant to hydrolyze in an acidic environment. Surfactants of this type can be utilized to enhance protein solubilization/enzyme digestion. Following hydrolysis to destroy the surfactant (which may chromatographic issues), there are generally two components formed - a hydrophilic one, and a hydrophobic one. By altering the chemistry of the hydrolysable linker, the polarity of the hydrophobic residue can be altered, allowing it to be solubilized by significantly less organic solvent, and to minimize the potential loss of peptide material and to expand the chromatographic conditions that can be utilized.
Patent WO-2019169270-A1 (WO)
Inventor: TSAI DONALD
IPC: A61K31/192
Filed: 2019-03-01
Abstract: This disclosure relates to compositions and methods for treating cancer. Specifically, this disclosure relates to bexarotene derivatives, methods for treating cancer, autoimmune disorders, and/or skin dermatitis, and/or methods for increasing peripheral blood counts and/or improving immune system function.
Patent WO-2019177804-A1 (WO)
Title: System, method, and apparatus for providing help
Inventor: GRAY MARK
IPC: G10L15/00
Filed: 2019-03-05
Abstract: A system for providing help includes at least one digital assistant and a wireless data interface for connecting the digital assistants to a server. A plurality of agent computers is connected to the server by a data network. Each of the at least one digital assistants is preprogrammed and centrally managed with at least one skill for recognizing a preprogrammed specific utterance and each of the at least one digital assistants is pre-configured to connect with the wireless data interface. After the preprogrammed specific utterance is detected by one of the digital assistants, that digital assistant initiates a request for help to the server and upon receiving the request for the help, the server assigns one of the agent computers and forwards the request for help to the one of the agent computers.
Patent WO-2019191310-A1 (WO)
Inventor: BAJAJ GEETIKA
IPC: H01L21/67
Filed: 2019-03-27
Abstract: Embodiments of the disclosure may provide a method and apparatus for cleaning an epi-chamber at a low temperature so that residues are quickly eliminated from a surface of the epi-chamber after a performing a low temperature epitaxial deposition process. Some of the benefits of the present disclosure include flowing a chlorine containing gas to an improved epi-chamber having UV capability to chlorinate and quickly remove the epitaxial deposition residues at a low cleaning process temperature. As such, residues are decreased or removed from the epi-chamber such that further processing may be performed.
Patent WO-2019191565-A1 (WO)
Inventor: ECCLES MATTHEW JAMES
IPC: H04L1/00
Filed: 2019-03-29
Abstract: Media-presentation-conscious scheduling protocols are disclosed that may associate a geographical location containing a thing with an identifier of the thing and allow later- found media works that pertain to the identifier to be presented at a mobile device before the device reaches a waypoint of the location. Alternatively or additionally, such protocols may respond to a predicted connectivity impairment of a traveling device by obtaining supplemental content to mitigate a predicted capacity shortage. Alternatively or additionally, such protocols may interrupt live stream content, insert on-demand content, and later return to live stream presentation automatically.
Patent WO-2019213061-A1 (WO)
Title: Systems and methods for checking safety properties
Inventor: SUTHERLAND ANDREW
IPC: G06F11/16
Filed: 2019-04-30
Abstract: In some embodiments, a system is provided, comprising enforcement hardware configured to execute, at run time, a state machine in parallel with application code. Executing the state machine may include: maintaining metadata that corresponds to one or more state variables of the state machine; matching instructions in the application code to transitions in the state machine; and, in response to determining that an instruction in the application code does not match any transition from a current state of the state machine, causing an error handling routine to be executed. In some embodiments, a description of a state machine may be translated into at least one policy to be enforced at run time based on metadata labels associated with application code and/or data manipulated by the application code.