baber/WOPTO huggingface dataset:
Patent HU-910336-D0 (HU)
Title: Process for purification of melphalane
Inventor: POOLE STEPHEN WILLIAM
IPC: A61P35/00
Filed: 1988-11-18
Abstract: The present invention relates to a new two-component pharmaceutical formulation of melphalan in which the two components comprise     a) freeze-dried mephalan hydrochloride and b) a solvent-diluent comprising a citrate, propylene glycol and ethanol. Substantially pure melphalan, substantially pure melphalan hydrochloride and methods for preparing them are also described.
Patent DK-279487-D0 (DK)
Inventor: BUENTEMEYER HEINO
IPC: C12M1/12
Filed: 1987-06-01
Abstract: PCT No. PCT/EP86/00566 Sec. 371 Date May 18, 1987 Sec. 102(e) Date May 18, 1987 PCT Filed Oct. 2, 1986 PCT Pub. No. WO87/02054 PCT Pub. Date Apr. 9, 1987.The invention relates to an apparatus and a process for the bubble-free gassing of liquids, especially of culture media for propagating tissue cultures by means of a porous membrane filament system, whereby liquid media and gas are introduced into the culture. The porous membrane filaments include both hydrophobic and hydrophobic filaments.
Patent DK-338085-D0 (DK)
Inventor: GOOSSENS JOHN
IPC: C08L83/04
Filed: 1985-07-24
Abstract: The electroviscous suspension is based on a mixture of aqueous silica gel with silicone oil as the liquid phase to which a dispersant is added. The dispersant consists of amino functional or silicon-functional polysiloxanes having a molecular weight above 800. The concentration of the dispersant is from 1 to 30% by weight and preferably from 5 to 20% by weight, based on the silica gel particles. Electroviscous suspensions such as these are distinguished by the fact that they are highly compatible with elastomeric materials, non-sedimenting, non-inflammable and physiologically acceptable. In addition, they are heat- and freeze-resistant over a wide temperature range and are largely unaffected by temperature and pressure in their viscosity.
Patent DK-373388-D0 (DK)
Inventor: LAMIRAUX CHRISTIAN JEAN
IPC: G01S1/24
Filed: 1988-07-05
Abstract: Signals are detected in a single receiving channel (1 - 4). The time difference between the reception of signals emitted by the transmitting stations of two different units are measured by detecting and measuring the signals emitted by the stations of one unit during the predetermined period of time specific to this unit and by detecting and measuring the signals from the transmitting stations of the second unit during the interval of time left over from the detection and measurement of signals coming from the first unit during the specific period of this first unit. 
<IMAGE>
Patent DK-380486-D0 (DK)
Inventor: THIEM JOACHIM
IPC: C07H5/02
Filed: 1986-08-08
Abstract: Alkylated glycosyl fluorides free from hydroxyl groups can be prepared by converting glycosyl fluorides which still contain hydroxyl groups into the alkylated compounds in the manner of Williamson's ether synthesis in the presence of basic systems by means of alkylating agents.
Patent DK-433284-D0 (DK)
Inventor: HOCH DIETRICH
IPC: A61K8/40
Filed: 1984-09-11
Abstract: PCT No. PCT/EP83/00350 Sec. 371 Date Aug. 10, 1984 Sec. 102(e) Date Aug. 10, 1984 PCT Filed Dec. 29, 1983 PCT Pub. No. WO84/02842 PCT Pub. Date Aug. 2, 1984.Process for a selective permanent shaping of the regrowth of hair, whereby the hair is at first treated with a liquid aqueous pretreatment substance, is rolled onto rollers, is treated with a aqueous reducing permanent shaping substance, rinsing, fixing it oxidatively and further treating it in a customaty manner, characterized in that the pretreatment and the permanent shaping substance is so selected that they form a separating layer at their contact face (uppermost layers of the rolled up hair) during contact, thus making an admixture of the pretreatment substance with the permanent substance more difficult or prevent it. Suitable combinations are for example: Pre=treatment substance containing either a high polymeric polycarboxylic acid polymer, whereby at least 25% Mol of these polymers consists of a free carboxylic acid group, or a water soluble aluminum salt in combination with an alkalic permanent shaping substance.
Patent DK-457786-D0 (DK)
Inventor: BICKLE WOLFGANG
IPC: F16C33/20
Filed: 1986-09-25
Abstract: 1. Process for producing a maintenance-free multilayer sliding bearing material, consisting of a combination of a metal backing made of steel, bronze or a high-strength aluminium alloy, provided with a rough primer layer (2), preferably a 0.1 to 0.35 mm thick, porous sinter-bonded bronze layer, iron layer, or aluminium alloy layer, and a bearing layer (3) consisting of a matrix (4) of polytetrafluoroethylene (PTFE), with which material the valleys of the rough primer layer are also filled and which may also optionally contain friction-reducing and wear-inhibiting additives of lead, molybdenum disulphide, graphite, carbon fibres, glass fibres, ceramic fibers, glass spheres, hollow ceramic spheres, barium sulphate, zinc sulphide, lead borosilicate, individually or in combination in a quantity of 5 to 40 % weight, characterized in that the PTFE, which has a grain size of =< 35 mu m, is moulded with an admixed extrusion assisting agent into a preform, said preform is extruded into a strip 1.5 to 5.0 mm thick, the strip is formed into a sheet 0.5 to 3.0 mm thick by conditioning calendering, the sheet, which is heated to 70 to 90 degrees C, is rolled on to the rough primer layer of the metal backing, which has been heated to 130 to 180 degrees C with a decrease in thickness to 0.1 to 1.0 mm, and subsequently the PTFE is sintered by continuous heating to approximately 400 degrees C and maintaining at this temperature for a short time.
Patent DK-496283-D0 (DK)
Inventor: LAURENT HENRY
IPC: C07J53/00
Filed: 1983-10-28
Abstract: 7 alpha -acylthio-1 alpha ,2 alpha -methylene-3-oxo-17 alpha -pregn-4-ene-21,17-carbolactones of Formula I    <IMAGE>  (I) wherein   <IMAGE>  and R is a lower saturated acyl radical of 2 to 4 carbon atoms, have a stronger antialdosterone effect and lower side effects than spironoloctone.
Patent DK-509887-D0 (DK)
Inventor: BONNEBAT CLAUDE
IPC: G11B7/24
Filed: 1987-09-28
Abstract: The invention relates to a polymeric, rigid, circular etched substrate (4) for a recording or optical reading disc, and the optical discs obtained by associating with the substrate (4), on which is deposited a sensitive reflective recording layer (3), an entrance face (1) which the laser beam crosses. 
<??>The substrate (4) is characterised in that, on the one hand, the polymer used to make it belongs to the family of thermotropic polymers and that, on the other hand, it is prepared by subjecting the thermotropic polymer to a moulding operation by injection into a mould equipped with a system for central injection of the polymeric material. 
<IMAGE>
Patent DK-537184-D0 (DK)
Inventor: AHM POUL HENRIK
IPC: A01C1/04
Filed: 1984-11-12
Abstract: A tape (1) or a packaged tape (20) provided in the longitudinal direction of the tape with strips (2) consecutively placed and containing bedding plants (3) ready for transplanting viable plantmaterial (10) capable of developing into beding plants. The tape (1) is preferably flat, windable into a roll or foldable and suited for mechanical handling (including mechanical transplanting). The strips (2) are consecutively connected by means of supporting tapes (4, 5) optionally forming part of the strips (2), and comprise two flat opposing wall-forming layers (4, 5) without any further growth medium therebetween and preferably made of a material in roll or sheet form such as plastics film, or paper with or without a plastics-coating enabling the supply and regulation of the quantity of air and water necessary for the establishment and development of the plants in the tape and securing the plants onto the tape.
Patent DK-589489-D0 (DK)
Inventor: RODMAN TOBY C
IPC: C07K19/00
Filed: 1989-11-23
Abstract: The present invention is directed to protamine-reactive, IgM antibodies, and their uses in prognosis, diagnosis, and therapy. In a specific embodiment, the invention relates to low affinity binding, protamine-reactive serum IgM antibodies. In particular, such antibodies can recognize a sequence comprising four arginyl residues, including a triplet, within a six amino acid residue sequence. Such antibodies may be natural antibodies (i.e., not induced). A low affinity subset of serum protamine-reactive IgM antibodies may be assayed for prognosis or diagnosis of AIDS. Such antibodies are detectable in sera of normal subjects and HIV-infected individuals who subsequently exhibit a significant period of latency, but are absent or deficient in sera of individuals diagnosed with AIDS and sera of HIV infected individuals, who though asymptomatic at the time of the sampling, proceed to AIDS within a relatively short time. The invention provides methods and diagnostic kits for the detection and/or measurement of the low affinity subset of protamine-reactive serum IgM antibodies, for the prognosis and diagnosis of AIDS and other immune system abnormalities.
Patent DK-589789-D0 (DK)
Inventor: VALLE FRANCESCO DELLA
IPC: A61P25/28
Filed: 1989-11-23
Abstract: Novel derivatives of lysophingolipids free from sialic acids which are N-acyllysosphingolipids having one of the two formulae: <CHEM> in which -A- stands for the group -CH=CH- or -CH2-CH2-, n1 is a whole number of between 6 and 18, n2 a whole number of between 11 and 15, X is a hydrogen atom or the residue of a monosaccharide or a disaccharide or phosphorylcholine and R represents an alkyl radical derived from a saturated or unsaturated aliphatic carboxylic acid having from 2 to 24 carbon atoms substituted by one or more polar groups. The lysosphingolipid derivatives of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.
Patent HU-905284-D0 (HU)
Title: Crystallic arg-lys-asp and arg-lys-asp-val of high purity and process for producing them
Inventor: NYEKI OLGA
IPC: C07K5/10
Filed: 1990-08-23
Abstract: The present invention relates to a process for the preparation of high purity crystalline forms of peptides Arg-Lys-Asp and Arg-Lys-Asp-Val from crude, amorphous peptides Arg-Lys-Asp and Arg-Lys-Asp-Val. The process is characterized in that the crude, amorphous peptide Arg-Lys-Asp or peptide Arg-Lys-Asp-Val is allowed to stand at room temperature with 5 to 20 unit volume of an ethanolic solution containing 0.5 to 4.0% by volume of acetic acid and 5 to 25% by volume of water, wherein the volume unit is calculated for the mass unit of the material and mass unit relates to volume unit as g relates to ml, then the crystallized peptide is separated from the crystalline suspension, preferably after cooling. Pharmaceutical compositions containing the crystalline forms of these peptides are also described.
Patent HU-896171-D0 (HU)
Title: Shaft bearing arrangement in the carriage of railway train
Inventor: AHLBORN GUENTER
IPC: F16C27/06
Filed: 1989-11-24
Abstract: The invention relates to the arrangement of the axle bearings in a running gear for rail vehicles, each axle bearing having on the outside a rubber-metal shell segment with an outer metal shell and an inner metal shell and a rubber intermediate layer and is mounted by means of this shell segment in the side cheek of the running gear. The object of the invention was to find an arrangement of the axle bearings for a running gear for rail vehicles in which a required primary vertical suspension is to be combined with a required horizontal  longitudinal rigidity of the axle bearings in a simple and cost-effective component. According to the invention, this object is achieved in that the rubber intermediate layer (4b) has break-throughs (6) running in the axial direction above the plane of the axle and in that metallic sub- segments (4d) are coaxially embedded in the rubber intermediate layer of the shell segment (4), beginning from the longitudinal sides of the latter. In this case there is arranged in each case one break-through (6) at the end of the sub-segments (4d) or one break-through (6) at the end of the sub-segments (4d) and at least one break-through (6) in the rubber intermediate layer (4b) above the break-throughs (6) at the end of the sub-segments (4d). <IMAGE>
Patent IT-8705241-D0 (IT)
Inventor: BEIER RUDOLF
IPC: F16D3/223
Filed: 1987-10-22
Abstract: The invention relates to a wheel bearing/constant velocity joint unit having a double row bearing 2 which has been provided with at least one inner bearing ring 12 which is separate from the wheel hub 1. The wheel hub and the outer part of the constant velocity joint are form-fittingly and non-rotatingly connected to each other by spur teeth. The spur teeth at the wheel hub are preferably produced by orbital pressing or orbital forging, and while the forming process takes place a collar is produced at the wheel hub which serves for axially tensioning the inner bearing rings, at least the one of the joint end.
Patent NO-900962-D0 (NO)
Inventor: MAGNUS ELO BOEGELUND
IPC: H02G3/04
Filed: 1990-02-28
Abstract: A tray for cables formed as a quadrangular channel upwardly open and doubled over at its free longitudinal edges includes at its one end a section with reduced dimensions in relation to the remainder of the tray.
Patent NO-905591-D0 (NO)
Inventor: GEORGE PASCAL
IPC: A61P13/02
Filed: 1990-12-27
Abstract: Compounds of general formula (I) 
<IMAGE>
 in which n represents the number 2, 3, 4 or 5, p represents the number 0 or 1, R1 represents a hydrogen atom or a methyl group, Xm represents one or more atoms or groups chosen from the following: hydrogen, fluorine, chlorine, methoxy, isopropyl or cyclopropyl, in the form of free bases or of addition salts with acids. 
<??>Use in therapy.
Patent NO-930906-D0 (NO)
Inventor: BJENNE KARL ANDERS
IPC: H04L12/70
Filed: 1993-03-12
Abstract: In the transfer of information packets in a network the information (7) is transmitted by the sending terminal station (1A) provided with a destination address field (9). The destination address field (9) comprises references or codes of the input lines/output lines or connection lines which are to be used when the information packet is retransmitted from nodes (5) in the network. In the corresponding way each information packet is in a node provided with address information in a return address field (11) indicating the connection line or combined input line/output line on which the information packet arrived to the node (5). Thereby the information packet, in a simple way, is provided with a return address and it may be utilized by the receiving terminal station (1B) for instance for the transfer of a receipt message.
Patent NO-942634-D0 (NO)
Inventor: OMURA SATOSHI
IPC: C12R1/66
Filed: 1994-07-13
Abstract: A FO-1289 substance of the formula   <IMAGE>   wherein R1, R2, R3 and R4 are hydrogen or acyl. A process for the production thereof comprises culturing the novel microorganism Aspergillus sp. FO-1289 FERM BP-4242 in a nutrient medium, accumulating the FO-1289 substance thus produced in the medium, and isolating the FO-1289 substance therefrom. Particular species of the FO-1289 substance comprise FO-1289A, in which R1, R2 and R3 are acetyl and R4 is hydrogen; FO-1289B, wherein R1 is propionyl, R2 and R3 are acetyl and R4 is hydrogen; FO-1289C, wherein R1 and R3 are acetyl, R2 is propionyl and R4 is hydrogen; and FO-1289D, wherein R1 and R2 are acetyl, R3 is propionyl and R4 is hydrogen.
Patent NO-950522-D0 (NO)
Inventor: MONTADOR JAMES HENRY
IPC: C08L101/16
Filed: 1995-02-10
Abstract: PCT No. PCT/GB93/01689 Sec. 371 Date Feb. 13, 1995 Sec. 102(e) Date Feb. 13, 1995 PCT Filed Aug. 10, 1993 PCT Pub. No. WO94/04607 PCT Pub. Date Mar. 3, 1994.Biodegradable polyesters derived from hydroxy alkenoic acids may be plasticised with an esterified hydroxycarboxylic acid which has at least three ester groups, at least some of the hydroxy groups being esterified with a carboxylic acid and at least some of the carboxy groups being esterified with an alcohol and/or phenol.
Patent NO-961579-D0 (NO)
Inventor: BATHE ANDREAS
IPC: C07D307/85
Filed: 1996-04-19
Abstract: 5-(Amino or piperazino)-benzofuran-2-carboxamides (I) are new. 5-(Amino or piperazino)-benzofuran-2-carboxamides of formula (I) and their salts are new. R1 = NH2, or piperazino; R2 = H, Cl, Br, OH, or OA; X = CONR4R5, or CO-Het; R4, R5 = H, A, or benzyl; A = 1-4C alkyl; and Het = imidazol-1-yl, triazol-1-yl or tetrazol-1-yl. An Independent claim is also included for the preparation of (I).
Patent NO-962024-D0 (NO)
Inventor: SANKARAM MANTRIPRAGADA
IPC: A61K47/48
Filed: 1996-05-15
Abstract: A multivesicular liposome composition containing at least one acid other than a hydrohalic acid and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number, provides a controlled release rate of the biologically active substance from the composition. A process for making the composition features addition of a non-hydrohalic acid effective to sustain and control the rate of release of an encapsulated biologically active substance from the vesicles at therapeutic levels in vivo.
Patent NO-965483-D0 (NO)
Inventor: FLORA ANTONIO DE
IPC: A61K39/44
Filed: 1996-12-19
Abstract: 5',5'-Pyrophosphates of non-naturally occurring nucleosides selected from thymine-3'-azido-2',3'-dideoxy-D-riboside, 5-fluorouracil-2'-deoxy-D-riboside, uracil-3'-azido-2',3'-dideoxy-D-riboside, guanine-2',3'-dideoxy-D-riboside, hypoxanthing-2',3'-dideoxy-D-riboside, cytosine-2',3'-dideoxy-D-riboside, and adenine-2',3'-dideoxy-D-riboside, are described as well as their manufacture and use as therapeutical pharmaceutical compositions or as pro-drugs encapsulated into biological carriers, e.g., transformed erythrocytes, for targeting to specific cell population responsible of the development of the pathological disorders.
Patent NO-971042-D0 (NO)
Inventor: JOSEF MICHAEL J
IPC: D21F1/00
Filed: 1997-03-06
Abstract: A papermaker's fabric includes a system of machine-direction (MD) yarns interwoven with a system of cross-machine direction (CD) yarns. The MD yarns are pairs of a first MD yarn and a second MD yarn. The first and second MD yarns are of a substantially rectangular cross section having identical width and thickness. The first and second MD yarns of each pair weave side-by-side as a single yarn with the CD yarns through the fabric. The CD yarns are of circular cross section. The fabric has a permeability to air less than 150 cubic feet per minute per square foot at 0.5 inch H2O-pressure. <IMAGE>
Patent NO-973777-D0 (NO)
Inventor: HECKEL KLAUS
IPC: B29C43/30
Filed: 1997-08-15
Abstract: Floor covering comprises a run of rubber material, with rubber granules embedded into its surface. There are different types of granule, with a grading of 0.1-40 mm. The covering has one or more visible and/or physical surface characteristic across and along it. The characteristic(s) alters along the run of the covering. The alteration occurs smoothly. Also claimed is the method of making the covering.
Patent NO-982522-D0 (NO)
Inventor: GIRARD FRANCOIS
IPC: A63C9/20
Filed: 1998-06-03
Abstract: The fastening (3) consists of a coupling element (6) which is fixed to the upper surface of the ski (2). It engages with a pin (9) projecting from the sole of the boot (1) in a zone between the tips of the toes and the metatarsal-phalangeal joints. It also incorporates a control member which provides a permanent direct or indirect contact between the tip of the boot sole and the ski when the heel is raised. <??>The control member has a stop (18) which limits the upward flexible movement of the coupling element (6) in relation to the ski. It also has a transverse guide for the coupling element, which is in the form of a metal wire or a spring vane with a hook-shaped end (7) for engaging with the boot sole pin (9) by the action of the fastening control lever (5).
Patent GB-0117402-D0 (GB)
Title: New antitumoral derivatives of et-743
IPC: A61K31/4995
Filed: 2001-07-17
Abstract: The present invention provides a compound of the general formula  Ia :   
wherein R 2 , R 4 , R 5  are each independently selected of H, C(=O)R', C(=O)OR', P=O(OR') 2 , substituted or unsubstituted C 1 -C 18  alkyl, substituted or unsubstituted C 2 -C 18  alkenyl, substituted or unsubstituted C 2 -C 18  alkynyl, substituted or unsubstituted aryl; 
wherein R 1  is C(=O)R" or C(=O)OR", and R" is an optionally substituted alkyl with at least 4 carbon atoms or an optionally substituted alkenyl, wherein the optional substituents are selected from aryl or heterocyclic; or R" is derived from an optionally protected amino acid; 
wherein R 6  and R 7  are both =O and the dotted lines indicate a quinone ring, or R 6  is -OR 3 , where R 3  is H, C(=O)R', C(=O)OR' substituted or unsubstituted C 1 -C 18  alkyl, substituted or unsubstituted C 2 -C 18  alkenyl, substituted or unsubstituted C 2 -C 18  alkynyl, substituted or unsubstituted aryl, R 7  is H, and the dotted lines indicate a phenyl ring; 
wherein X 2 , X 3 , X 4 , X 5 , X 6  are independently selected of H, OH, OR', SH, SR', SOR', SO 2 R', C(=O)R', C(=O)OR', NO 2 , NH 2 , NHR', N(R') 2 , NHC(=O)R', CN, halogen, substituted or unsubstituted C 1 -C 24  alkyl, substituted or unsubstituted C 2 -C 18  alkenyl, substituted or unsubstituted C 2 -C 18  alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaromatic; 
wherein X 1  is independently selected of OH, CN, (=O), or H; 
wherein each of the R' groups is independently selected from the group consisting of H, OH, NO 2 , NH 2 , SH, CN, halogen, C(=O)H, C(=O)CH 3 , CO 2 H, PO(OR') 2 , substituted or unsubstituted C 1 -C 18  alkyl, substituted or unsubstituted C 2 -C 18  alkenyl, substituted or unsubstituted C 2 -C 18  alkynyl, substituted or unsubstituted aryl; 
wherein when R 2 , R 3 , R 4 , and R 5  are substituted, the substituents are each independently selected from the group consisting of OH, OR', SH, SR', SOR', SO 2 R', C(=O)R', C(=O)OR', NO 2 , NH 2 , NHR', N(R') 2 , NHC(O)R', CN, halogen, =O, substituted or unsubstituted C 1 -C 18  alkyl, substituted or unsubstituted C 2 -C 18  alkenyl, substituted or unsubstituted C 2 -C 18  alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heterocyclic.
Patent GB-0129952-D0 (GB)
Title: Doorposts and doorframes
IPC: E05B47/06
Filed: 2001-12-14
Abstract: A door assembly includes a door post 5 which is rotatable about a longitudinal axis 7 and is formed with a recess shaped to receive the side edge of a door 3. The door assembly may include a frame comprising a head rail between the door supporting door post 5 and a slam door post 4 and a means of enabling rotation of each door post relative to the head rail about a longitudinal axis. The means of rotation may be supporting the ends of the door posts within bearing races, or the end of each door post may carry a spindle which seats within a suitably shaped cap secured to the head rail. The door posts may be circular in cross-section and the depth of the recesses on the doorposts may be less than the circumference of the door posts. Preferably the shape of the recess complements the shape of the door edge, the recess may be "V" shaped.
Patent GB-0203788-D0 (GB)
Title: The folding of a clamping table
IPC: B25H1/18
Filed: 2002-02-19
Abstract: A worktable having a leg supports (2 & 3) linked by strut (4) in normal working mode may have its leg supports repositioned one with another for alternative working modes, here shown with leg support (3) providing an extension to the top frame support 1, an extension leg (18) connected by strut (4) supports leg support (3) in a horizontal plane and a sliding element (20) providing the same essential form features as the top frame support (1) permitting the operational footprint of jaws (7 & 9) to be extended over the elongated top frame support provided by leg support (3).