baber/WOPTO huggingface dataset:
Patent NZ-742663-A (NZ)
Title: Vaccination with mica/b alpha 3 domain for the treatment of cancer
Inventor: WUCHERPFENNIG KAI
IPC: A61K47/00
Filed: 2016-12-05
Abstract: The present invention relates to a fusion protein comprising a monomeric ferritin subunit protein fused to a MIC alpha 3-domain protein. The fusion protein has therapeutic applications for treating treating cancer in a subject by eliciting an immune response against a MIC alpha 3-domain polypeptide.
Patent NZ-743316-A (NZ)
Title: Anti-dr5 antibodies and methods of use thereof
Inventor: RADEMAKER RIK
IPC: C07K16/28
Filed: 2016-12-01
Abstract: The present invention relates to monospecific or bispecific antibody molecules that specifically bind the human DR5 antigen. The invention relates in particular to DR5-specific antibody molecules of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding leading to the induction of DR5 signalling, apoptosis and cell death. Specifically, the mutation may be E430G, E345K, or S440Y. The invention further relates to a combination of antibody molecules binding different epitopes on DR5. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of cancer using these compositions.
Patent NZ-747822-A (NZ)
Title: Medical device with anti-rotation push tab
Inventor: BORNHOFT STEPHEN
IPC: A61M25/02
Filed: 2017-03-23
Abstract: A medical device (100), comprising a hub (102) or housing (118) having a push tab (112) including a main portion extending radially from an upper surface of the hub or housing, and at least one anti-rotation feature (114, 116) for resisting rotation of the hub or housing. A cannula (103) is directly or indirectly connected to the hub or housing. The medical device may be a catheter, the cannula may be a catheter tube, and the hub or housing may be a catheter hub or an introducer needle tip shield of the catheter. The anti-rotation feature is in the form of a rib with a top surface having a cradle shape. The anti-rotation feature prevents rotation of the push tab out of reach of the finger if the hub rolls while being advanced.
Patent NZ-749275-A (NZ)
Title: Synthesis of n-(heteroaryl)-pyrrolo[2,3-d]pyrimidin-2-amines
Inventor: SMITH ALEXANDER
IPC: A61K31/519
Filed: 2017-06-29
Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
Patent NZ-783271-A (NZ)
Title: Outlet connection assembly and method of making the same
Inventor: HUBY RONALD JAMES
IPC: A61M16/00
Filed: 2014-06-24
Abstract: An airflow tube 5130 releasably attachable to a chassis of a respiratory pressure therapy (RPT) device that includes a blower to provide pressurized air to a patient interface to treat a respiratory disorder in a patient. The tube comprises a first portion 5130b constructed from a first material and having a seal 5132 that is configured to contact and seal against a humidifier reservoir, the seal 5132 forming an inlet end configured to receive air pressurized by the blower, and a second portion 5130a constructed from a second more rigid material and with an outlet end 5134 configured to be connected to an air circuit to direct pressurized air to the patient interface. The first material is overmoulded onto the second material of the second portion such that the first portion and the second portion are detachable from the chassis in one piece.The airflow tube comprises a bend positioned between the inlet end and the outlet end, and the first material and the second material each form part of the bend.
Patent PT-104255-A (PT)
Title: Ligantes para agregados à base de cal viva e pozolanas, processo para a sua produção e respectivas utilizações na construção
Inventor: CARTAXO FERNANDO RAIMUNDO SIMOES
IPC: C04B24/08
Filed: 2008-11-18
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A NOVOS LIGANTES À BASE DE CAL VIVA E POZOLANAS EM PÓ, PODENDO AINDA COMPREENDER UM OU MAIS ACTIVADORES ALCALINOS, PARA AUMENTAR AS CARACTERÍSTICAS MECÂNICAS, E/OU AINDA GORDURA, A FIM DE LHE CONFERIR PROPRIEDADES DE HIDROFUGAÇÃO. A ADIÇÃO DESTE TIPO DE COMPOSTOS POSSIBILITA AINDA O CONTROLO DO TEMPO DE PRESA DAS MISTURAS COM ELE EFECTUADAS.TRATA-SE, ASSIM, DE LIGANTES PREDOMINANTEMENTE AÉREOS, QUANDO A PERCENTAGEM DA POZOLANA FOR MAIOR OU IGUAL A 30%, OU HIDRÁULICOS, NO CASO CONTRÁRIO.NA EXECUÇÃO DE REVESTIMENTOS, OS LIGANTES DA PRESENTE INVENÇÃO, CONDUZEM A UMA REDUÇÃO DRÁSTICA DA FENDILHAÇÃO POR RETRACÇÃO RESTRINGIDA, EM RELAÇÃO À VERIFICADA PELA UTILIZAÇÃO DE OUTROS CIMENTOS E CAIS HIDRÁULICAS. ESTES LIGANTES PODEM SER APLICADOS NA CONSTRUÇÃO DE EDIFÍCIOS, INFRA-ESTRUTURAS VIÁRIAS, NA EXECUÇÃO DE ALVENARIAS EM FUNDAÇÕES, EM ELEVAÇÃO DE PAREDES E SEUS REVESTIMENTOS EXTERIORES E INTERIORES, ESTABILIZAÇÃO DE TERRAS, NA CONSTRUÇÃO DE NOVOS EDIFÍCIOS, CICLOVIAS, CAMINHOS PEDONAIS E BARRAGENS DE TERRA, ENTRE OUTRAS.
Patent RU-94007652-A (RU)
Inventor: DZHON LOUSON BEVEN
IPC: A24D3/10
Filed: 1994-03-10
Abstract: FIELD: filtering materials. SUBSTANCE: extruded filtering material which is destructible and includes plastic material or inorganic substance whose melting point is higher than the working temperature, polysaccharide expansion medium, binder and water. These components are supplied to extruder and subjected to extrusion which includes lowering of the pressure after extrusion from head tip up to a value near 70 bars to provide for swelling of extrudate to produce cellular structure. When the elements of tobacco smoke are exposed to normal natural weather conditions they are disintegrated without leaving the melted amalgamation of plastic or inorganic substance. EFFECT: higher efficiency.
Patent RU-94010700-A (RU)
Inventor: MOLITVIN E I
IPC: B60V1/14
Filed: 1994-03-28
Abstract: FIELD: transport. SUBSTANCE: vehicle has load carrying structure 1 with platform 2, flexible side guard railing, source to create higher pressure in zone P, and wheeled running gear. Higher pressure source is made in form of propelling blades 5 and 6 arranged in one horizontal plane along vehicle centerline and installed in lower portion of upper belt 7 of guard railing lower edges of blades are arranged above lower edges of guard railing belt. Wheeled running gear has additional wheel installed in front of front wheel set 9 and furnished with drive mechanism 12 and control mechanism 13. Distance between axes propelling blades is less than 2R where R is radius of blade. Blades are installed with angular displacement relative to each other. Guard railing has ring recirculation chamber 15 formed by flexible outer coating 16 secured concentrically over contour 0. Louver slots 17 are made in upper overblade section over perimeter of side surface of guard railing upper belt. Recesses made in front and rear parts of platform serve to communicate blade space 0 with atmosphere. EFFECT: increased lift, reduced air and power consumption by using velocity head at forming air cushion. 4 cl, 2 dwg
Patent RU-94017330-A (RU)
Inventor: GREBNEV E N
IPC: A61N2/00
Filed: 1994-05-10
Abstract: FIELD: medicine. SUBSTANCE: method involves detecting the state of hematological, immunological and biochemical values normalization in exposing patient autoblood to magnetic field action. Toxic grain structure of leukocytes is reduced under the influence of magnetic field and their phagocytic activity grows. Young epitheliocytes and epithelial phagocytosis phenomena are to be observed at the 4-5 day of treatment witnessing high level of regeneration response. EFFECT: reduced recurrence level; accelerated way to reach remission.
Patent RU-94020114-A (RU)
Inventor: KUZNETSOVA V V
IPC: C05C3/00
Filed: 1994-05-31
Abstract: FIELD: mineral fertilizers, agriculture. SUBSTANCE: composition consists of nitrogen fertilizer and plant growth regulating agent that is a mixture of mono- and dicarboxylic acid sodium salts. Ammonium sulfate, carbamide and nitroammophoska can be used as nitrogen fertilizer. Use of the novel composition ensures to increase cereal crops productivity and potato by 15-20%, enhance content of starch and vitamin C, decrease fertilizer dose addition by 10-15%, diminish their acidity. EFFECT: enhanced effectiveness.
Patent RU-94025211-A (RU)
Inventor: REL KIN K B
IPC: F41H11/12
Filed: 1994-07-06
Abstract: FIELD: self-propelled armored vehicles for removed and installation of ground mine fields. SUBSTANCE: armored vehicle uses a turbojet engine connected through a movable joint to gas conduits controlled from the driver seat, inclined to the ground before the vehicle caterpillars. A pack with mines is freely installed in the rear part of the armored vehicle frame, connected to inclined chutes for rolling-down of mines to the ground. Each chute has a share and a tamping-type roller at the end. The process of removal of mines consists in supply of a high-power gas jet from the turbojet engine to the gas conduits; which blows out the mines from the ground aside where they explode. Unexploded mines are machine-gunned. At installation of mine fields mines placed in packs are fed through the inclined chutes into trenches dug by the shares, and are filled up with ground by means of the tamping-type rollers. EFFECT: enhanced efficiency, universal ability to carry out removal and installation of mine fields simultaneously. 2 dwg
Patent RU-94027094-A (RU)
Inventor: JURLIN L A
IPC: A61B5/00
Filed: 1994-07-29
Abstract: FIELD: medicine. SUBSTANCE: method involves evaluating sympathico- parasympathic balance index (SPBI) value from R-R interval distribution as relation of two parameters: mode amplitude to number of positions (N) forming the distribution. Logarithmic scale is used. R-R interval estomate resolution capacity is defined to be equal to 0.01 s. Positive value and magnitude of the SPBI determine domination and domination measure of sympathic component of organism cardiovascular system, respectively. Negative value and magnitude of the SPBI determine domination and domination measure of parasympathic component of organism cardiovascular system, respectively. The strength or weakness of the human nervous system is evaluated by taking into consideration mean time values describing simple motor response to weak sensory irritants or SPBI value. EFFECT: unbiased evaluation of human attention properties.
Patent RU-94029747-A (RU)
Inventor: KOSJAKOV V M
IPC: E01B25/00
Filed: 1994-08-09
Abstract: FIELD: railway building. SUBSTANCE: additional rail is placed in parallel to the main track at a distance equal to the distance between rails in the main track. The third additional rail may be laid without failing the traffic on the main track. Transportation means may be moved on completion the laying down the third rail with wheel-to-wheel spacing equal to 1520 mm and 3040 mm. All members of the main railway may be used at wide-gage track. EFFECT: low-cast railway building.
Patent RU-94030325-A (RU)
Inventor: KREMNEV A A
IPC: B66F9/07
Filed: 1994-08-17
Abstract: FIELD: storehouse equipment. SUBSTANCE: truck has frame 1, four full-swing non-driven wheels, axle 3 hinge mounted on frame 1 and rigidly connected to truck drive consisting of electric motor 4 with two shaft extensions, straight reduction gear 5 and angular reduction gear 6, drive rolls 7 and 8 mounted on axes of symmetry of frame 1, two platforms 9 for operator and balancing mechanism. Drive with two relatively perpendicular drive rolls is rigidly coupled with hinge axle 3 on ends of which operator's platform is secured in equilibrium. Truck frame is installed on full-swing non-driven wheels which makes it possible to use truck in storehouses both at manual control in any direction of motion and with electric drive but only in relatively perpendicular directions of motion. EFFECT: enlarged operating capabilities. 1 dwg
Patent RU-94030914-A (RU)
Inventor: MALYSHEV A A
IPC: E01D15/14
Filed: 1994-08-23
Abstract: FIELD: crossing-bridge means, folding pontoons. SUBSTANCE: pontoon link has two extreme and two middle pontoon interconnected with hinges. Transoms of the pontoons are equipped with eye- bolts and rollers. Method for unfolding pontoon link on ground includes installation pontoon-carrying truck so that truck platform is opposite the middle of the folded link on the side of extreme pontoon. Then hoist pull cables are run upon the truck, and ends of pull cables are to be fastened to the extreme pontoon, and tensioned. New feature of the method includes the fact that extreme and middle links of the pontoon are joined in pair, for instance, with screw tension rods. Pull cables are laid on snatch blocks of lifting boom of the pontoon-carrying truck and fasten cable ends by loading eye-bolts near bottom of the nearest extreme pontoon. Middle pontoons are unfolded using truck hoist up to resting their bottom on ground. Screw tension rods are taken off. Ends of pull cables are detached from loading eye-bolts and are secured to tow eye-bolts on the bow of the transom of the same pontoon. Extreme pontoon is turned using the hoist to rest with the bottom on ground. Ends of pull cables are detached from tow eye-bolts. Platform of the pontoon-carrying truck is installed opposite another extreme pontoon. Ends of pull cables are secured to tow eye-bolts. The extreme pontoon is turned using the hoist to rest the bottom on the ground. Ends of pull cables are detached from tow eye-bolts. EFFECT: the method allows one to avoid failure in hinges interconnecting the pontoons, and unfold the pontoon links in reliable manner without additional operations to remove soil attached to the surfaces between pontoon links.
Patent RU-94034366-A (RU)
Inventor: TKACHENKO JU P
IPC: C12N1/16
Filed: 1994-09-30
Abstract: FIELD: food industry. SUBSTANCE: method involves preparing seed yeast, their washing and storage in water treated by permanent magnetic field at magnetic induction value in treatment zone 30-120 mT. Medium where seed yeast were obtained can be treated by permanent magnetic field also. Method is used in brewery, alcohol, kvass, wine making, bread baking. EFFECT: improved method of yeast preparing.
Patent RU-94036421-A (RU)
Inventor: RESHETTSOV N V
IPC: B60K17/02
Filed: 1994-09-29
Abstract: FIELD: transport engineering; vehicle transmissions. SUBSTANCE: in proposed invention character of interaction of clutch rotating members and sharp decrease of inertia moment of clutch member coupled with gearbox drive shaft are provided. For this purpose distance between radial walls 13 and 14 and between walls 15 and 16 arranged in line is several times smaller than distance between cylindrical walls and thanks to it circular space is extended radially. EFFECT: enhanced operating properties of clutch, reduced axial sizes and provision of favorable operating conditions for transmission members. 6 cl, 4 dwg
Patent RU-94043888-A (RU)
Inventor: FARBER V M
IPC: B23K9/04
Filed: 1994-12-14
Abstract: FIELD: metallurgy; welding; surface hardening and restoration of rolls. SUBSTANCE: wear-resistant powder material is applied in layers on iron-carbide base of article. First layer is faced at mode providing 40-50% mixing of main metal and filler, and following layers, at modes providing reduction of fraction of previous layer in following one up to 6-10% to last faced layer. EFFECT: provision of high wear resistant and crack resistant metal.
Patent RU-94044501-A (RU)
Inventor: VERGASOV F P
IPC: B01D45/14
Filed: 1994-12-26
Abstract: FIELD: devices for cleaning compressed gases of liquid in oil producing industry and in transportation. SUBSTANCE: shaft of separation element is coaxially mounted on bearings inside housing; mounted additionally on this shaft are liquid cleaning filters and sprayers for spraying liquid inside each bearing. Inner surface of separation shaft is provided with passages for taking liquid; filter inlets are connected with passages and filter outlets are connected with liquid sprayers. During operation of separator, part of liquid moving over walls of separation shaft gets in liquid taking passages and then it enters filters via passages where liquid (gas condensate) is cleaned of suspended particles. After cleaning, liquid is directed to sprayers and then to bearings for lubricating, cooling and washing them. Used liquid is thrown out of bearings beyond separation element housing under action of centrifugal forces. EFFECT: enhanced reliability and high safety of operation of separator due to facilitated operation of its bearings and simplified construction of their lubrication system.
Patent RU-94046411-A (RU)
Inventor: KLAUS OGE SVENSGOR BRETTING
IPC: A61P3/08
Filed: 1993-06-07
Abstract: FIELD: vitamins. SUBSTANCE: invention relates to compounds of the formula (I) where X means hydrogen and hydroxy-group; Rand Rmean hydrogen or C-C-hydrocarbyl radical; or taken together with carbon atom supporting the group X they can form C-C-carbocyclic ring; Q means a single bond or C-C-hydrocarbylene biradical R,Rand/or Q can be optional substituted with one or more deuterium atoms or fluorine, and its derivatives. Synthesized compounds show antiinflammatory and immunomudulating action and high activity with regard to induction of differentiation and proliferation inhibition of some cells. EFFECT: improved method of synthesis, enhanced effectiveness of compounds.
Patent RU-95101905-A (RU)
Inventor: EVSEEV I F
IPC: E04B1/38
Filed: 1995-02-13
Abstract: FIELD: construction engineering. SUBSTANCE: this relates to buildings with metal frameworks. Beam-to-column joining unit has supporting rib of beam located on flat of column with mounting clearance relative to flat of column and connected with it by coupling bolts, and compensating member which is made in the form of hollow thrust bolts installed in threaded holes of supporting rib of beam at points of location of coupling bolts with possibility of coming into contact with flange of column. Coupling bolts are inserted through hollow thrust bolts and are secured to them with one end. EFFECT: high efficiency. 2 dwg
Patent RU-95102584-A (RU)
Inventor: BARANOVA L G
IPC: A61N1/00
Filed: 1995-02-21
Abstract: FIELD: medicine. SUBSTANCE: method involves using Hall converter as transducer for controlling mental action effectiveness. Constant voltage is supplied to current outlets of Hall converter and electric voltage changes are measured on the Hall outlets of the converter under periodic action exerted upon it by inductor. EFFECT: enhanced reliability in detecting mental action effects.
Patent RU-95102787-A (RU)
Inventor: LANTSA EHMMANUEHL
IPC: C08F4/46
Filed: 1995-02-24
Abstract: FIELD: chemistry of polymers. SUBSTANCE: claimed invention is concerned with method for treating copolymers with polycarboxylic acid cyclic anhydride. Such copolymers are formed at copolymerization initiation stage using alkaline metal (Me) based catalysts and subjected to deactivation so that they have end group of alkaline metal alcoholate (O- Me). EFFECT: more efficient treatment method.
Patent RU-95104627-A (RU)
Inventor: ZHALDAK N I
IPC: E01C19/05
Filed: 1995-04-06
Abstract: FIELD: hydraulics. SUBSTANCE: mechanism comprises housing with gas power accumulator and cocking chamber. There are a striker with a head and a step valve spring-loaded by flexible power accumulator inside the chamber. The outer side of the valve and inner side of the housing define a chamber that is periodically connected with the cocking chamber. Grooves are provided on the inner side of the housing at the top of the space. The grooves and the step valve form a labyrinth slot. The step valve can interact with the housing and overlap the labyrinth as well as defines the delivery space. The inner side of the step valve and head of the striker define the under-valve space which is in communication with the delivery space through passageways in the valve when the striker is cocked. The space is constantly connected with the drain pipe line. The cocking chamber is constantly in communication with the delivery pipe line. EFFECT: improved design. 1 dwg
Patent RU-95104681-A (RU)
Inventor: MITROFANOV D G
IPC: G01S13/02
Filed: 1995-03-30
Abstract: FIELD: radiolocation, tracking radars. SUBSTANCE: in known similar station parameter of identification depended on range to target which decreased quality of identification if additional measures for compensation for errors caused by difference of distances to target were not take. It was proposed to insert two delay lines, generator of reset pulses and commutator with simultaneous removal of N-1 squarers, N-2 additional adders, N-2 full wave rectifiers from N channel identification unit and replacement of two adders with amplitude storage circuits with reset. This will allow to use single-channel identification unit and make parameter of identification invariant to range to target. EFFECT: increased probability of radar identification of aerial targets by tracking radars within wide band of ranges.
Patent RU-95105164-A (RU)
Inventor: UVE JOKHENTGEN
IPC: F22D1/36
Filed: 1994-05-09
Abstract: FIELD: power plants. SUBSTANCE: steam power plant contains boiler working on fossil fuel, steam-water circulating loop for generation of superheated high-pressure steam for steam turbine, economizer for transfer of heat of flue gases to feed water, air preheater for transfer of heat of flue gases to blast air, as well as devices for dedusting and desulfurization of flue gases; nitrogen removal device may be also provided, if required. For optimization of heat exchange in air preheater during operation and for reduction of heat losses during start of steam power plant, proposed heat exchange system has section for flow of recirculating air section for flow of heat-transfer agent; air section is connected on side of inlet with blast air outlet of air preheater and with blast air inlet of air preheater on side of outlet. EFFECT: enhanced efficiency.
Patent RU-95105553-A (RU)
Inventor: AGAFONOV V D
IPC: B01D45/06
Filed: 1995-04-11
Abstract: FIELD: filtering arrangements. SUBSTANCE: filter that may be used in sausage-making injectors has a casing with inlet and outlet fittings for air, net member, and fastening facilities. Casing is separated with partitions having openings forming a varying-section channel. Openings made in conical partitions have flangings and those in cylindrical partition are H- shaped and inclined, whereas partition members between openings are deformed so as to touch on pulling counter-directed protrusions of H-shaped openings. EFFECT: increased capacity and reliability of device.
Patent RU-95106869-A (RU)
Inventor: DEMIN A V
IPC: G02B23/00
Filed: 1995-04-28
Abstract: FIELD: optical instrumentation engineering, telescopes, binoculars, geodetic instruments and other visual optical devices. SUBSTANCE: invention is related to devices designed to measure and to guide to objects. It solves problem of provision for possibility of measurement of object or guidance to object viewed through telescopic system, provision for immobility of grid image relative to viewed object when eyes of observer are displaced relative to exit pupil of telescopic system simultaneous provision of direct image of observed object. Proposed Galilei telescopic system includes objective lens of positive focal power, eye-piece of negative focal power and optical component with grid applied on first surface in path of ray between objective lens and eye-piece. Value of air gap between objective lens and optical component with grid is found from relation, dis value of gap between objective lens and grid, mm;is value of rear focal segment of objective lens, mm; dis value of air gap between optical component with grid and eye-piece, mm dis thickness of optical component with grid along optical axis of telescopic system, mm;is value of front focal segment of eye-piece, mm. Surface of objective lens last in path of ray is made concave, has ray splitting coat, faces grid with concavity and curvature radius of it is determined from following relation, where R is curvature radius of concave surface with ray splitting surface, mm. EFFECT: enhanced operational capabilities.