baber/WOPTO huggingface dataset:
Patent MD-3236985-T2 (MD)
Inventor: WEINSCHENK TONI
IPC: C07K7/08
Filed: 2015-12-16
Abstract: Prezenta invenţie se referă la peptide, proteine, acizi nucleici şi celule pentru utilizare în metode imunoterapeutice. În particular, prezenta invenţie se referă la imunoterapia cancerului. În plus, prezenta invenţie se referă la epitopii peptidici ai celulelor T citotoxice asociate tumorii, singuri sau asociaţi cu alte peptide asociate tumorii, care pot servi, de exemplu, drept componente farmaceutice active ale formulelor de vaccin care stimulează răspunsurile imunitare antitumorale sau pentru stimularea celulelor T ex vivo şi transferarea în pacienţi. Peptidele legate de molecule ale complexului major de histocompatibilitate (MHC), sau peptidele ca atare, pot fi, de asemenea, ţinte ale anticorpilor, ale receptorilor solubili ai celulelor T şi ale altor molecule de legare. În special, prezenta invenţie se referă la mai multe secvenţe peptidice noi şi variantele acestora derivate din moleculele HLA de clasă I şi de clasă II ale celulelor tumorale umane care se pot folosi în formule de vaccin pentru inducerea de răspunsuri imunitare antitumorale sau drept ţinte pentru dezvoltarea de compuşi sau celule active din punct de vedere farmaceutic/imunologic.
Patent TR-200000148-T2 (TR)
Title: 1-(4-Karbazoliloksi)-3-(2-metoksifenoksi) etilamino)-2-propanol' ün modifikasyonu, gerekli proses ve farmasötik bileşimler.
Inventor: REINHOLZ ERHARD
IPC: A61P9/00
Filed: 1998-07-18
Abstract: Elimizdeki bulus 1-(4-karbazoliloksi) -3-(2-(2-metoksifenoksi)etilamino)-2-propanol' ün (karvedilol) termodinamik açidan kararli sekilde yeni bir modifikasyonu, farmakolojik olarak kabul edilebilir tuzlari ya da bunlarin optik olarak aktif sekilleri, hazirlanmasi için prosesler ve bunu içeren farmasötik bilesimlerle ilgilidir.
Patent TR-200001954-T2 (TR)
Title: Faktör XA'nın önleyicileri olarak indol türevleri.
Inventor: DEFOSSA ELISABETH
IPC: A61K31/404
Filed: 1998-12-10
Abstract: Bu bulus, kan pihtilastirici proteinlerin önlenmesi ve daha özel olarak, içinde R1a, R1b, R1c, R1d, R2, R3, R4, ve A'nin istemlerde belirtildigi gibi tarif edildigi formül (I) indol türevleri ile ilgilidir. Formül (I) bilesimleri, kan pihtilasma enzim faktörü Xa'nin önleyicileridir. Bulus ayni zamanda formül (I) bilesimlerinin hazirlanmasi için süreçler, faktör Xa faaliyetinin  önlenmesi ve kan pihtilasmasinin önlenmesi için yöntemler, formül (I) bilesimlerinin, tromboembolik hastaliklar gibi faktör Xa faaliyetinin önlenmesi ile engellenebilecek ya da tedavi edilebilecek hastaliklarin tedavisi ve önlenmesi için kullanimi ve formül (I) bilesimlerinin bu tür hastaliklara uygulanacak ilaçlarin hazirlanmasinda kullanimi ile ilgilidir.
Patent TR-200002803-T2 (TR)
Title: MRP1 inhibe etmek için yöntemler.
Inventor: GRUBER JOSEPH MICHAEL
IPC: C07D498/04
Filed: 1999-04-07
Abstract: Mevcut bulus, direncin kismen veya bütünüyle MRP1'den kaynaklandigi dirençli neoplazmalarin inhibe edilmesi için yararli olan bir formül (I) bilesigi ile ilgilidir.
Patent TR-200101956-T2 (TR)
Title: Sıcak kanlılara zararı olmayan, bitki korumada ve ev haşerelerinin öldürülmesinde kullanılan fungisit, bakteriosit, nematisit ve insektisitlere doğal alternatifler
Inventor: TUZUN SADIK
IPC: A01N65/00
Filed: 1999-10-08
Abstract: Aktif içerigi, Labiatae ve Umbellifera familyalarina dahil olan bitkilerden en az birinden elde edilen bir uçucu yag veya bir komponenti olan ve böcekleri, funguslari, nematodlari ve bakterileri uzaklastirici veya öldürücü etkisi olan bir terkip açiklanmistir. Bu terkipleri kullanarak böcekleri, funguslari, nematodlari ve bakterileri uzaklastirmak veya öldürmenin mümkün olacagi metodlar da açiklanmistir.
Patent DE-602004001926-T2 (DE)
Inventor: BORHAN TAVAKOLI ABBAS
IPC: F16K27/00
Filed: 2004-06-16
Granted: 2007-12-06
Abstract: The production of a semi-product of a CuZnPbSn alloy includes a spinning operation which does not include nor is it followed by a thermal treatment stage. Independent claims are also included for the following: (a) a finished product obtained fron the semi-product; and (b) the production of the finished product by deformation or machining, which does not include a thermal treatment stage.
Patent DE-602004002387-T2 (DE)
Inventor: STOOP ALFONS
IPC: H05F3/02
Filed: 2004-01-14
Granted: 2007-09-20
Abstract: Method for manufacturing an object with conductive properties from a plastic composition, wherein a suitable thermoplastic plastic composition is selected for the object, wherein metal fibres are added to the plastic composition, the metal fibres are distributed substantially homogeneously through the plastic composition, and this composition containing metal fibres is then subjected to a treatment in order to form the object. In this manner an object is obtained with conductive properties which are retained.
Patent DE-602004003468-T2 (DE)
Inventor: CHARLET GABRIEL
IPC: G02B6/34
Filed: 2004-04-08
Granted: 2007-03-29
Abstract: A method of transmitting digital signals over an optical transmission system is described. The method comprises the following steps: generating a signal according to the differential phased shift keying (DPSK) format, forwarding the DPSK signal to an optical delay filter (16), and using an output signal of the optical delay filter (16) as a signal according to the phase shaped binary transmission (PSBT) format. <IMAGE>
Patent DE-602004004791-T2 (DE)
Inventor: KOOIJMANS KEES R
IPC: E04H4/08
Filed: 2004-10-15
Granted: 2007-12-06
Abstract: The present invention provides a sealing plug for liquid-tight sealing off hollow floatation elements of a strip for a cover of a liquid-filled container. The sealing plug comprises an end plate and at least two protrusions extending from the end plate. The at least two protrusions comprise at least two lips. The end plate and the protrusions are formed of a first material and the lips are formed of a second material, the first material being harder than the second material. The at least two lips extend in a first direction including an angle between +/-90° and +/-180° with the direction in which the sealing plug is pushed into the hollow floatation elements and preferably have decreasing height starting from the end plate toward a free extremity of the protrusion. The protrusions have a circular shape in cross-section
Patent DE-602004011401-T2 (DE)
Inventor: BAILEY NICHOLAS
IPC: C07D409/12
Filed: 2004-12-15
Granted: 2008-12-24
Abstract: The present invention relates to novel benzazepine derivatives of structure (I) having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders. These compounds act as histamine H3 antagonists.
Patent DE-602005004085-T2 (DE)
Inventor: GOTO TAKAHIRO
IPC: B41C1/10
Filed: 2005-08-17
Granted: 2008-12-11
Abstract: Disclosed is a planographic printing plate precursor including a photosensitive layer containing an infrared absorber, a polymerization initiator, a polymerizable compound and a binder polymer and a protective layer laminated on a support in this order, wherein the protective layer contains a mica compound and at least one polyvinyl alcohol selected from the group consisting of a polyvinyl alcohol having a saponification value of 90 mol% or less and an acid modified polyvinyl alcohol. Also disclosed is a method of making a planographic printing plate, the method including exposing the planographic printing plate precursor to light having a wavelength of 750 nm to 1400 nm and then carrying out developing step at a conveying speed of 1.25 m/min. or more with substantially no heat treatment and no water-washing treatment.
Patent DE-602005005018-T2 (DE)
Inventor: SAHINOJA MIKKO
IPC: G06F15/177
Filed: 2005-01-28
Granted: 2008-06-12
Abstract: The invention relates to a method for defining the nodes of a management structure used in device management in a device management system. In the arrangement, case sensitivity information is associated with at least one node to define whether to distinguish between upper-case and lower-case letters. At least one node is defined according to the case sensitivity information.
Patent DE-602006000204-T2 (DE)
Inventor: KIM SOENG-HUN
IPC: H04L12/56
Filed: 2006-04-04
Granted: 2008-02-21
Abstract: A method and apparatus for reporting a Buffer Status (BS) using Node B-estimated BS information in a mobile communication system are provided. A Node B-estimated BS and an actual BS of a User Equipment (UE) are monitored. A value of the Node B-estimated BS is compared with a first threshold value. If the Node B-estimated BS value is less than the first threshold, a determination is made as to whether the value of the actual BS is more than a second threshold. If the actual BS value is more than the second threshold, a Buffer Status Report (BSR) indicative of the actual BS is transmitted to a Node B.
Patent DE-60004995-T3 (DE)
Inventor: GILSTRING GERT
IPC: A01B23/04
Filed: 2000-06-07
Granted: 2009-09-10
Abstract: The machine has disc implements with at least one beam supporting them. The vertical discs (9) on each beam being, in groups, arranged parallel to one another and inclined at an angle form the normal to the longitudinal direction of the beam. A share (10) is between consecutive discs (9) on the same beam so that it cultivates and cuts off rootlets present in the soil ridge formed between the grooves of the respective discs. The share is in two parts (14,15), the lower one of which forms a horizontal cutting part projecting away from the adjacent disc (9). A manually adjustable displacement member is included and may be e.g. a rigging screw or a transmission gear, or it may be pneumatically adjustable device operated from the driver's cab.
Patent DE-60029323-T3 (DE)
Inventor: LAIRD PETER
IPC: C12Q1/6858
Filed: 2000-05-12
Granted: 2017-03-30
Abstract: There is disclosed an improved high-throughput and quantitative process for determining methylation patterns in genomic DNA samples based on amplifying modified nucleic acid, and detecting methylated nucleic acid based on amplification-dependent displacement of specifically annealed hybridization probes. Specifically, the inventive process provides for treating genomic DNA samples with sodium bisulfite to create methylation-dependent sequence differences, followed by detection with fluorescence-based quantitative PCR techniques. The process is particularly well suited for the rapid analysis of a large number of nucleic acid samples, such as those from collections of tumor tissues.
Patent DE-60106394-T3 (DE)
Inventor: HOLTZMAN DAVID
IPC: A61K/
Filed: 2001-02-26
Granted: 2013-07-25
Abstract: A method to treat conditions characterized by formation of amyloid plaques both grophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Aß peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Aß.
Patent DE-69422514-T3 (DE)
Inventor: BUDTZ PETER
IPC: A23C19/032
Filed: 1994-04-22
Granted: 2003-12-24
Abstract: PCT No. PCT/DK94/00163 Sec. 371 Date Dec. 29, 1995 Sec. 102(e) Date Dec. 29, 1995 PCT Filed Apr. 22, 1994 PCT Pub. No. WO94/24880 PCT Pub. Date Nov. 10, 1994A process of producing cheese in improved yields, wherein a recombinant aspartic protease, derived from Rhizomucor miehei or Rhizomucor pusillus, is added to milk in sufficient amounts to effect clotting of the milk, after which the resulting curd is processed in a manner known per se for making cheese.
Patent DK-1041223-T3 (DK)
Inventor: LAU WOLFGANG
IPC: E05C9/18
Filed: 2000-03-07
Granted: 2003-06-16
Abstract: The system of frame fittings has at least one fitting (2-7) whose main body (21,31,41,51,61,71) has at least one fixture-cav (25,26;35;45;55;65;75,76) and which each consist of a top and bottom body (21.1,21.2,31.1,31.2;41.1,41.2;51.1,51.2;61.1,61.2;71.1,71.2). The fitting bodies have at least one group of guides consisting o guide parts (22,23;32,33;42,43;52,53;63,62;72,73) spaced apart. The fixture cavities have at least one screwing line (15.1;14.2;14.3) formed and spaced apart from a guide part. The fitting bodies of all the fittings are the same height (28,38,48,58,68,78) from the top edge of the top body to the guide edge of the guide parts.
Patent DK-0988850-T3 (DK)
Inventor: WONG PATRICK S L
IPC: A47G21/18
Filed: 1996-07-17
Granted: 2005-01-24
Abstract: An oral active agent delivery system for delivering discrete units of active agent formulation in admixture with a fluid is disclosed. Said system comprises:   a hollow active agent formulation chamber (10) having a first end (16) and a second end (18) and containing an active agent formulation in the form of a plurality of discrete units, said ends being adapted to pass fluid during delivery of the active agent formulation; and a fluid passing active agent retainer for preventing release of the discrete units from the first end (16) of the chamber while permitting fluid entry into the chamber; and is characterised in that said fluid passing active agent retainer comprises a restriction in the cross-sectional area of said first end of said chamber, and each of said discrete units has a diameter greater than said restriction.   <IMAGE>
Patent DK-1101407-T3 (DK)
Inventor: VAN AREM EVERHARDUS JACOBUS FR
IPC: A23C19/032
Filed: 2000-11-17
Granted: 2006-06-12
Abstract: The invention relates to a method for preparing a cheese of the hard or half-hard type, wherein capsular polysaccharide-forming bacteria are introduced into the cheese milk. In addition, the invention relates to a cheese which is obtained according to this method and to the use of these bacteria to obtain a cheese having a smoother consistency.
Patent DK-1099859-T3 (DK)
Inventor: KRUSCHINSKI ANDREAS DIPL-ING
IPC: F15B21/047
Filed: 2000-10-17
Granted: 2005-09-19
Abstract: The method involves detecting (6,7) the working pressure in the working circuit of each hydraulic motor (4,5) during the initiation of the closing movement and controlling it via a controller so that the same working pressure exists in both working circuits at the end of the gripper closing process. The arrangement has a sensor in the hydraulic line leading to each sensor. Independent claims are also included for the following: an arrangement for pressure equalization in hydraulic motors for driving the lifting and gripper closing cables of a cable crane.
Patent DK-1196679-T3 (DK)
Inventor: KLEIN ARNO
IPC: E06B9/58
Filed: 2000-06-17
Granted: 2007-04-10
Abstract: The aim of the invention is to create a device for guiding machine elements (2) along a guideway (8), especially a rail, chain or cable, which is improved by the provision of a simple construction and a protection against overloading. To these ends, a detent connection having at least one detent element (12, 13) is provided on the machine elements (2). Said detent connection is arranged between the machine element (2) and a guide element (20) that engages inside the guideway (8), whereby the detent element(s) (12, 13) positively engage(s) inside recesses (10, 11) located on the machine element (2).
Patent DK-1198871-T3 (DK)
Inventor: KRAMER MARKUS
IPC: F04B49/06
Filed: 2000-07-13
Granted: 2006-05-22
Abstract: The invention relates to a device for detecting a malfunction of a machine driven with a variable rotational speed by an electric motor, whereby the motor is switched off when a malfunction occurs. A regulating device which controls the motor records the operating values of the motor during a learning function and said operating values can then be used to detect malfunctions. The method steps used for this purpose provide a learning function of the regulating device before activating the malfunction detection. To this end, the machine and/or a unit actuated by the machine runs through all possible operating states in which the operating values of the motor recorded during the learning function are, in their association with the machine and/or the unit driven by the motor, stored, brought forward and used for monitoring malfunctions.
Patent DK-1122198-T3 (DK)
Inventor: BALLESTRAZZI ARIS
IPC: B65H15/00
Filed: 2001-01-19
Granted: 2005-01-10
Abstract: A turning device for graphic publishing products in a conveyor line and/or packaging machine that can be combined with a push conveyor (14) for the advancement of products (11), spaced out one after the other, including a supporting member (16) bearing in sequence a first conveyor unit (17) to pickup at least one of the products (11) off the conveyor line, a grasping and turnover unit (18) of at least one of the products (11), a second conveyor unit (19) to deposit at least one of the products (11), turned upside down on the conveyor line, the conveyor units (17,19) being operated to advance in phase with the push conveyor (14) and being movable between a working position and a disengaged position with the conveyor line. <IMAGE>
Patent DK-1263480-T3 (DK)
Inventor: WOO LECON
IPC: A61L2/00
Filed: 2001-01-26
Granted: 2010-05-10
Abstract: A device and method for inactivating pathogens in therapeutic fluids with sterilizing radiation in a continuous flow arrangement while exhibiting radiation dose uniformity and narrow residence time distribution of the fluid within the device. The device (10) comprises a radiation permeable cylindrical tube (12) having a concentric cylindrical rotor (14) disposed therein, thereby providing a thin gap (16) therebetween. A top plate (18) having a fluid outlet (26) and a bottom plate (20) having a fluid inlet (24) seal the cylindrical tube (12). The inlet (24) and outlet (26) are both in fluid communication with the thin gap (16). A rotor shaft (36) is diposed axially through the cylindrical rotor (14) and is connected to a motor (30). A pump provides fluid flow through the device (10). A radiation source provides sterilizing radiation to the fluid through the cylindrical tube (12). As the fluid flows, the motor (30) drives the rotor (14) to impart Taylor vortices to the fluid flow, which exchanges the fluid closer to the cylindrical tube (12) with the fluid closer to the rotor (14).
Patent DK-1323128-T3 (DK)
Inventor: MARTIN PHILIPPE
IPC: G06K19/077
Filed: 2001-09-11
Granted: 2006-04-10
Abstract: A contact free electronic label, such as those designed to be affixed on conductive surfaces, has an insulating support one side of which bears a first winding having its ends connected to an electronic circuit. The opposite side of the support bears a second winding whose ends are connected to conductive pads. This opposite side of the support is designed to be secured to a conductive surface via an insulating dielectric layer. The labels are designed to be affixed on products having conductive surfaces such as laser discs, gas bottles and the like.
Patent DK-1336024-T3 (DK)
Inventor: BAECKMAN ERIC
IPC: E05F15/12
Filed: 2001-10-19
Granted: 2006-05-22
Abstract: A device for opening and closing a pivotally mounted door leaf including an actuator, which is displaceably and/or rotatingly arranged in a housing and connected to the door leaf and which, during displacement/rotation, actuates the door leaf, and a drive motor which is connected to the actuator for providing displacement/rotation thereof.
Patent DK-1266829-T3 (DK)
Inventor: BRUNSEN HERMANN
IPC: B65B9/13
Filed: 2002-02-27
Granted: 2005-04-11
Abstract: Device for surrounding a load has a roller (14) arranged in a hook (1) in the horizontal moving path of the roller (13) on the upper edge section (17). Preferred Features: The roller is arranged in the known manner central to the hook and/or the roller (14). The roller (14) has the cross-section of the edge section of the hook. The roller (14) can be reversibly driven.
Patent DK-1247863-T3 (DK)
Inventor: GODDARD AUDREY
IPC: C07K16/18
Filed: 1999-06-02
Granted: 2006-05-15
Abstract: Isolated nucleic acids chosen from 135 sequences given in the specification are new. An isolated nucleic acid (I) having at least 80% sequence identity to: a nucleotide sequence that encodes a polypeptide comprising an amino acid sequence chosen from 135 sequences given in the specification; or one of 135 nucleotide sequences (given in the specification). Independent claims are also included for: an isolated nucleic acid which comprises the full-length coding sequence of the DNA deposited under any of 135 ATTC accession numbers as given in the specification; a vector comprising (I); a host cell comprising the vector of (2); a process for producing PRO polypeptides comprising culturing the host cell of 93) under conditions suitable for expression of the PRO polypeptide and recovering the PRO polypeptide from the cell culture; an isolated PRO polypeptide having at least 80% sequence identity to an amino acid sequence chosen as above or encoded by a DNA as in (1); a chimeric molecule comprising a polypeptide as above fused to a heterologous amino acid sequence; an antibody which specifically binds to a PRO polypeptide as above; an isolated extracellular domain of a PRO polypeptide; an isolated PRO polypeptide lacking its associated signal peptide; and an isolated polypeptide having at least about 80% amino acid sequence identity to (8) or (9). ACTIVITY : None Given. MECHANISM OF ACTION : None Given.
Patent DK-1354054-T3 (DK)
Inventor: DURRANT LINDA GILLIAN
IPC: A61K48/00
Filed: 2002-01-28
Granted: 2006-02-13
Abstract: The invention relates to the use of a polypeptide that comprises i) a first portion comprising the part of human Fc that binds to CD64, and ii) a second portion comprising one or more heterologous T cell epitopes for stimulating a cytotoxic T cell response. The polypeptide may be an antibody that may be used to stimulate a cytotoxic T cell response against pathogens and tumor cells in patients in need of such treatment.
Patent DK-1414446-T3 (DK)
Inventor: CROENLEIN JENS
IPC: A61K31/425
Filed: 2002-07-30
Granted: 2006-01-16
Abstract: The use of 2-amino-4,5,6,7-tetrahydro-6-n propylaminobenzothiazole (pramipexole) (I) or a salt or hydrate as an anticonvulsant, optionally with a second active compound, for preventing or treating cerebral or generalized seizures and epilepsy, is new.
Patent DK-1371779-T3 (DK)
Inventor: STROPPIANA FERNANDO
IPC: E01C13/08
Filed: 2001-02-13
Granted: 2006-07-31
Abstract: A particulate filling material or infill (3) adopted to be dispersed between the filiform formations (2) of a synthetic-grass structure in such a way as to maintain the filiform formations (2) in a substantially upright condition. The infill (3) consists of a substantially homogeneous mass of a granular material chosen in the group made up of polyolefin-based materials and vinyl-polymer-based materials, preferably recycled ones. <IMAGE>
Patent DK-1581174-T3 (DK)
Inventor: BELLGRAU DONALD
IPC: C12N15/62
Filed: 2003-12-16
Granted: 2018-06-18
Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.
Patent DK-1449511-T3 (DK)
Inventor: NEUDECKER BIRGIT
IPC: A61Q19/08
Filed: 2000-05-19
Granted: 2007-02-05
Abstract: The use of idebenone (I) (i.e. 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone) or its derivative (I') is claimed in cosmetic or topical dermatological preparations. ACTIVITY : Dermatological; antiinflammatory; antiallergic; immunosuppressive. MECHANISM OF ACTION : Antioxidant; radical scavenger; apoptosis inhibitor. In macrophage-LDL antioxidant tests (I) at 10 MicroM completely prevented lipid peroxide formation after 8 and 24 hours, and was markedly more effective than ascorbic acid at 50 mu M, alpha -tocopherol at 100 mu M or glutathione at 50 mu M.