baber/WOPTO huggingface dataset:
Patent PT-751794-E (PT)
Inventor: MINICK STEVEN E
IPC: A61M39/28
Filed: 1995-05-10
Abstract: A disposable pumping cassette having an integral auxiliary flow control and pressure monitoring member is used for delivering a medicinal fluid to a patient. The pumping cassette includes an elastomeric member mounted in a rigid body having an inlet and an outlet. An inlet valve and an outlet valve on the cassette are opened, and the flow control is positioned to allow the medicinal fluid to flow freely through the cassette, priming it before the outlet is connected to the patient. The cassette is then coupled to an associated pump driver, closing the flow control to disable free fluid flow through the cassette, and the outlet of the cassette is coupled in fluid communication with the patient's body. The medicinal fluid is drawn into a pumping chamber formed in the rigid body as a plunger of the associated pump driver is drawn up from the elastomeric membrane at a recess formed in the rigid body. The plunger is then advanced downwardly, forcing the elastomeric membrane into the pumping chamber to deliver the medicinal fluid to the patient. The pressure of the fluid delivered to the patient is monitored through contact of the auxiliary flow control member with the elastomeric membrane over an outlet channel of the cassette.
Patent PT-771813-E (PT)
Inventor: OKYAYUZ-BAKLOUTI ISMAHAN
IPC: C07F9/6561
Filed: 1996-10-21
Abstract: Alkyl xanthine phosphonates and phosphine oxides of formula (I) are new: at least one of R1, R3 = a group of formula (XI), and the other (when not (XI)) is H, 1-6C alkyl, 2-6C alkyl interrupted by 1-2 non-adjacent O atoms, 1-8C alkyl (optionally substituted by oxo or 1-2 OH), 2-6C alkenyl, benzyl (optionally 1-5 times substituted by 1-4C alkyl or 1-4C alkoxy), 3-6C cycloalkyl or (1-4C alkyl)-(3-6C cycloalkyl); R4, R5 = H, OH or 1-6C alkyl; A, B = 1-4C alkyl, 1-6C alkoxy, OH or benzyloxy; E = a covalent bond or 1-5C alkyl; R2 = H, 1-6C alkyl, 2-6C alkyl interrupted by 1-2 non-adjacent O atoms, benzyl (optionally substituted 1-5 times by 1-4C alkyl or 1-4C alkoxy), Ph, 3-6C cycloalkyl or (1-4C alkyl)-(3-6C cycloalkyl); D = H, F, Cl, Br or I. The following compounds are excluded: (4-(1,3-dimethyl-xanthin-7-yl)-butyl)-phosphonic acid diethyl ester; 5-(1,3-dimethoxy-xanthin-7-yl)-pentyl-phosphonic acid; 4-(1,3-dimethyl-xanthin-7-yl)-butyl-phosphonic acid; 3-(1,3-dimethyl-xanthin-7-yl)-propyl-phosphonic acid.
Patent PT-768886-E (PT)
Inventor: BOLTON ANTHONY ERNEST
IPC: A61K35/14
Filed: 1996-05-03
Abstract: Vasospastic disorders such as Raynaud's phenomenon are treated by administering to the patient an aliquot of autologous blood which has been subjected simultaneously to heat, ultraviolet irradiation and oxidative environment so as to render the blood aliquot capable of generating in the patient's bloodstream after administration a population of stimulated leukocytes having upregulated expression of CD25 cell surface markers, along with an enhancement of endothelial function in the patient.
Patent PT-865304-E (PT)
Inventor: HEATON KEITH PATRICK
IPC: A61F13/00
Filed: 1996-11-14
Abstract: The invention relates to wound treatment apparatus for applying negative pressure to a superficial wound in a mammal which comprises a porous pad (102) of open, intercommunicating cellular flexible foam, a suction tube (101) for connecting the porous pad to a pump (6), a surgical drape for forming an air-tight seal over the wound site and over the pad and over a connector for connecting the pad to the suction tube, said connector comprising a disc-like cup (601) having its lower face in contact with said porous pad, and having a spout (602) for connecting to the end of the suction tube remote from the pump to the wound site. <IMAGE>
Patent PT-805153-E (PT)
Inventor: VILLALOBOS ANABELLA
IPC: C07D295/185
Filed: 1997-04-15
Abstract: Muscarinic receptor agonists of the formula:- <CHEM>  wherein   X is NR<4>R<5>, (C1-C10)alkyl or optionally substituted (C3-C10)cycloalkyl,   n is an integer from one to three;   m is an integer from one to three;   p is an integer from one to three;   Y is N or CH; Z is NR<7>R<8>, optionally substituted (C3-C10)cycloalkyl, (C1-C10)alkyl, pyridyl or optionally substituted phenyl;   R<2> is optionally substituted phenyl;   R<3> is optionally substituted phenyl; R<4> and R<5> are independently (C1-C10)alkyl or R<4> and R<5> taken together with the nitrogen atom to which they are attached form a (five to nine)-membered saturated heterocyclic ring.   R<6> is hydrogen or (C1-C6)alkyl; and R<7> and R<8> are independently (C1-C10)alkyl or R<7> and R<8> taken together with the nitrogen atom to which they are attached form a (five to seven)-membered saturated heterocyclic ring.
Patent PT-803253-E (PT)
Inventor: BAROCHEZ BRUNO HUET DE
IPC: A61K9/22
Filed: 1997-04-23
Abstract: Tablet matrix in which sustained release of sodium tianeptine (I) is controlled using a polymeric cellulose derivative and a calcium salt is new.
Patent PT-906404-E (PT)
Inventor: SUBIRANA RAFAEL PI
IPC: C11D3/39
Filed: 1997-06-04
Abstract: The proposal is for novel thickening agents for aqueous hydrogen peroxide solutions, containing, in relation to the active substance content of the agent, (a) 10 to 90 wt % fatty acid alkanolamides, (b) 5 to 20 wt % alkyl ether sulphates, (c) 0 to 5 wt % alkyl ether phosphates and (d) 0 to 60 wt % alkyl polyglycol ether, with the proviso that the weights add up to 100 wt %. The agents ensure a reliable and permanent viscosity setting and make the inclusion of perfumes easier without the risk of turbidity.                                       00000
Patent PT-920510-E (PT)
Inventor: POTTER ANDREW A
IPC: A61K47/48
Filed: 1997-08-08
Abstract: New immunological carrier systems, DNA encoding the same, and the use of these systems, are disclosed. The carrier systems include chimeric proteins which include a leukotoxin polypeptide fused to one or more selected GnRH multimers which comprise at least one repeating GnRH decapeptide sequence, or at least one repeating unit of a sequence corresponding to at least one epitope of a selected GnRH molecule. Under the invention, the selected GnRH sequences may all be the same, or may correspond to different derivatives, analogues, variants or epitopes of GnRH so long as the GnRH sequences are capable of eliciting an immune response. The leukotoxin functions to increase the immunogenicity of the GnRH multimers fused thereto.
Patent PT-1000571-E (PT)
Inventor: JANE CABAGNERO RAMON
IPC: B60N2/28
Filed: 1999-11-05
Abstract: The carrycot is formed by two members namely being a front (1) and a back member (2), said members being linked to each other in a hinged connection, said carrycot comprising a seat (4) arranged on said front member. The carrycot is characterized in that the seat is at its back edge linked in a hinged connection to the bottom (6) of the front member (1) of the carrycot, said seat (4) being at its middle region and through links (7) also linked in a hinged connection to the front region of the back member (2) of the carrycot, at a point (8) being eccentrically arranged with respect to the hinge axis of the hinged connection between both members (1,2) of the carrycot. Said hinged connection between both members of the carrycot is provided with means to limit its swinging arc. <IMAGE>
Patent PT-1071051-E (PT)
Inventor: GIBERNAU ANTONIO MONTSERRATE
IPC: G07F9/10
Filed: 1999-04-05
Abstract: It includes a microwave oven (3) with a front door (31) that can slide vertically and a conveyor band (6) with a horizontal section extending as far as the interior of the oven; the products fall on the band by gravity from storage means (5). The oven may also have a tilting bottom (32) for expulsion of the products. The storing devices (5) are attached to a frame (4) hinged to the housing (1) and are provided with a ramp (57) for the extraction of the products through an outlet opening (55) arranged above the band (6).  The machine is compact, mechanically simple and has a reduced cost. <IMAGE>   <IMAGE>
Patent PT-1144261-E (PT)
Inventor: BLIN PATRICK
IPC: B65D5/475
Filed: 1999-08-30
Abstract: A carton and blank (10) for forming a carton for beverage containers which carton includes a series of hinged panels (12, 14, 16, 18, 20, 22) forming a sleeve and end closure panels (34, 36, 38, 40) hinged to at least one associated hinged panel (12, 14, 16, 18, 20, 22) for closing, at least in part, the opposite ends of a sleeve. The said carton includes handle means by which the carton can be carried, said handle means comprising a strap (38) connected to opposed end panels (38, 40) having a user part (74) which is in substantially co-planar relationship with said one hinged panel (18) when in a stored condition. The strap (98) is so connected at its opposite ends to said end closure panels (38, 40) as to provide a surplus of material to enable said user part to be brought into a position of use.
Patent SG-44687-G (SG)
Title: N-naphthoylglycine derivatives
IPC: A61K31/165
Filed: 1987-05-15
Abstract: Herein disclosed are N-naphthoylglycine derivatives having aldose reductase inhibiting activity. The derivatives are useful for treating diabetic complications. The derivatives are of the formula <CHEM> (where R<1> is hydrogen lower alkyl, lower alkenyl or phenylmethyl, R<2> is hydrogen or lower alkyl and R<3>, R<4> and R<5> are hydrogen or specified substituents) and therapeutically acceptable salts of the compounds wherein R<2> is hydrogen. Certain intermediate aminoacids useful in the preparation of the above mentioned derivatives also have aldose reductive inhibiting effects.
Patent IE-810139-L (IE)
Title: Leak proof dispensing pump
IPC: F04B9/14
Filed: 1981-01-27
Abstract: A dispensing pump having a unitary plunger defining a main pump chamber and functioning as a discharge valve upon accumulation of pressure causing the plunger to shift open, includes a container vent which is positively sealed against leakage therethrough even upon nudging the plunger during storage, shipment and handling of the pump. The pump includes a fixed position and a reciprocable plunger head having a discharge passage, the inside of the head and the top of the piston being complementarily contoured for expelling accumulated air from the pump chamber directly out of the discharge during priming. Otherwise, the pump chamber may be placed in communication with a vent chamber which opens into the container through the vent so that any accumulated air in the pump chamber may be vented into the container as an aid in priming. The volume beneath the plunger head may be enclosed as an air chamber so that the air therein may be vented into the container upon opening the container vent to assist in pump priming. And, the plunger is designed to effect a quick or a slow opening of the discharge passage.
[US4402432A]
Patent IE-810145-L (IE)
Title: A gaseous fluid pump;
IPC: B05B9/04
Filed: 1981-01-27
Abstract: The liquid reservoir tank of plant spraying equipment of the haversack type is pressurised by a pair of foot pumps (10) worn by the operator under his shoes (14). Co-operating formations (28 and 29) are provided within the chamber formed by the resiliently deformable air pump body (13) of each foot pump (10) which has concertina sidewalls (23) so that the enclosure surrounded by the sidewalls (23) is substantially filled by the formations (28 and 29) when it is collapsed. 
[EP0033640A2]
Patent IE-790190-L (IE)
Title: Purine derivatives
IPC: C07D473/34
Filed: 1979-02-01
Abstract: Novel 9-[3-(4-amino-piperidino)-propyl]-adenine derivatives of the formula <IMAGE> wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom, an aryl radical, a lower alkyl radical, a hydroxy lower alkyl radical, or together with R1 and the nitrogen atom to which they are attached form a heterocyclic ring, and R3 is a hydrogen atom or an acyl radical, or salts thereof with pharmacologically acceptable acids, characterized by anti-allergic, anti-inflammatory and anti-oedematous activity.
[US4212866A]
Patent IE-790304-L (IE)
Title: DIBENZO £b,d| PYRANS
IPC: A61P25/22
Filed: 1979-02-16
Abstract: {PG,1 1-Hydroxy-3-substituted-tetrahydro and hexahydrodibenzo{8 b,d{9 pyrans having an amino group or amino derivative at the 9-position are useful as analgesics, anti-depressants, anti-anxiety agents, hypotensive agents, and intermediates. Pharmaceutical formulations containing such 9-amino derivatives are provided, as well as a method of treating hypertension.
[US4152450A]
Patent IE-33210-L (IE)
Title: Producing fibrous web
IPC: D01D5/42
Filed: 1969-04-28
Abstract: 1,245,670. Fibrillated sheet. CHEVRON RESEARCH CO. 1 May, 1969 [3 May, 1968], No. 22336/69. Heading D1R. A regular fibrous web is formed by feeding a uniaxially oriented polymer film 13 under a controlled tension e.g. 600-3000 p.s.i. between the rotating surfaces of a driven toothed roller 11 having parallel helical rows of substantially equidistant teeth 14 and a driven presser roller 12 having helical grooves 15 which mate with the rows of teeth. The film is fed at an angle α such that it contacts the surface of the latter roller before that of the former and is supported on the presser roller surface. The rollers rotate synchronously in opposite directions at a peripheral speed 1.5-20 times greater than the film speed thus forcing the teeth 14 through the film 13 info the grooves 15 to cut slits in the film. The resulting fibrillated film is withdrawn at such an angle # that the film remains in contact with the surface of the presser roller 12 until after the teeth 14 have disengaged the film. The film may be made of polyolefine, polyesters or polyamides.
[GB1245670A]
Patent IE-780696-L (IE)
Title: Electrolytic graining of aluminium.
IPC: B41N3/03
Filed: 1978-04-10
Abstract: Aluminium or aluminium alloy is electrolytically grained using alternating current and an aqueous electrolyte comprising specified amounts of hydrochloric acid and a monocarboxylic acid containing from 1 to 4 carbon atoms, preferably acetic acid. The grained aluminium or alloy may be coated with a light sensitive layer to form a light sensitive plate for use in the production of lithographic printing plates by photomechanical techniques.
[US4172772A]
Patent IE-800724-L (IE)
Title: Analgesic and myotonolytic preparations
IPC: A61K31/505
Filed: 1980-04-09
Abstract: Compositions having enhanced analgesic and myotonolytic activity comprising as active agents (a) an analeptically active quinazolinone and (b) a centrally acting myotonolytic.
[US4442084A]
Patent IE-44096-L (IE)
Title: Carton operation
IPC: B31B50/76
Filed: 1976-04-15
Abstract: A plurality of collapsed open ended sleeve-type cartons are withdrawn in sequence from a hopper by feeder means which engages a single wall of each carton and moves in such a direction as to cause another wall of the carton to engage fixed cam means having a camming surface disposed at an angle to the general direction of feeding movement of cartons from the hopper so as partially to set up the open ended sleeve-type carton. A carton feeding operation is performed by a main feeding arm to which a supplementary feeder arm is pivotally connected and biased to impart desired pressure to the carton to facilitate setting the carton up during initial stages of a withdrawal operation. After a carton is withdrawn from the hopper, the feeder means moves into cooperative relationship with a carton stripper which insures that the feeder arm disengages the carton and immediately thereafter an oscillatable pusher advances the carton in partially set-up condition into cooperative engagement with a plurality of spaced flight bars which control the movement of the open ended carton while loading of the carton is effected from both ends simultaneously by suitable guides following which carton end closure panels are folded by machine guides into closed positions and subsequently interlocked by locking means which operates in synchronism with the flight bars to complete the package.
[US3991660A]
Patent FI-824030-L (FI)
Inventor: KOENIG WOLFGANG
IPC: A61P31/04
Filed: 1982-11-23
Abstract: A peptide of the formula B1-B2-A1-A2-X in which B1 denotes a basic aminoacid, B2 denotes a basic aminoacid, A1 denotes an aromatic aminoacid, A2 denotes an aromatic aminoacid and X denotes an aminoacid in which the carboxyl group can be esterified, a process for the preparation thereof and the use thereof.
Patent IE-791106-L (IE)
Title: Gypsum set accelerator.
IPC: C04B28/14
Filed: 1979-08-08
Abstract: A gypsum set accelerator for use in the production of gypsum wallboard comprises a tube or ball milled mixture of gypsum and up to 20 percent by weight of the gypsum of a synthetic water-soluble solid surfactant. A process for the manufacture of gypsum wallboard is also described comprising spreading between paper sheets an aqueous slurry of calcium sulphate hemihydrate defined above at a rate of between 0.5 and 15 kilograms per 100 square meters (1 and 30 pounds per 1000 square feet) of gypsum wallboard, and allowing the slurry to set. The accelerator has high potency and appears to provide wallboard of increased compressive strength.
[US4298394A]
Patent IE-781122-L (IE)
Title: Elbow joint prosthesis
IPC: A61F2/00
Filed: 1978-09-02
Abstract: A humero-ulnar elbow joint prosthesis comprises a metallic ulnar component 14 in the form of a generally oval head having a curved stem corresponding to the curve of the upper medullary canal of the ulna 16, and a plastics humeral component 10 in the form of a cup having a trough at the inner surface for cooperation with the oval head of the ulnar component and a stud on the outer surface of the cup for location of the humeral component relative to the humerus 13, the arrangement being such that in use the oval head glides within the trough during elbow flexion permitting both a linear change in carrying angle and a limited degree of cyclic rotation. Preferably, the ulnar component 14 comprises a vitallium alloy and the humeral component 10 comprises high density polyethylene. <IMAGE>
[GB2030867A]
Patent IE-871185-L (IE)
Title: Immunogenic conjugates
IPC: A61K39/385
Filed: 1987-05-11
Abstract: An immunogenic conjugate which is the reductive amination product of an immunogenic capsular polymer fragment having at least one reducing group and derived from a bacterial capsular polymer of a bacterial pathogen, and a bacterial toxin or toxoid. The invention also relates to methods for the preparation of the conjugates, a vaccine containing the conjugates which elicits effective levels of anti-capsular polymer antibodies in humans. Also disclosed are methods for inducing active immunization against systemic infection in young mammals caused by bacterial pathogens comprising the administration of an immunogenic amount of the abovedescribed conjugate. In a preferred embodiment, the capsular polymer fragment prior to conjugation has at least one aldehyde group at each end of the fragment. The final conjugate made with such capsular polymers has a lattice or network structure, and provides extremely high levels of anti-capsular polymer antibodies in infants.
Patent IE-39898-L (IE)
Title: Xanthine derivatives
IPC: A61K31/522
Filed: 1974-06-14
Abstract: Compounds of general formula <IMAGE> (I) wherein one of the groups R1 and R3 is a straight-chain or branched oxoalkyl group consisting from 5 to 8 carbon atoms and the oxygen atom is attached to a non-terminal carbon atom and is separated from the nearest ring nitrogen atom by at least 3 carbon atoms in ( omega -1)-oxoalkyl groups and by at least 4 carbon atoms in oxoalkyl groups in which the oxygen atom is separated from the terminal carbon atom by more than one carbon atom, R2 and the other one of groups R1 and R3 are straight chain or branched alkyl groups containing from 1 to 12 carbon atoms but wherein that group R1 or R3 which is other than an oxoalkyl group may also be hydrogen, one nitrogen-bound substituent being hydrogen or alkyl containing more than 1 carbon atom, and physiologically acceptable acid addition salts thereof, a process for their preparation and pharmaceutical compositions containing said compounds.
[US4289776A]
Patent IE-45352-L (IE)
Title: Detemination of polyunsaturated fat levels in body fluids
IPC: G01N33/487
Filed: 1977-07-01
Abstract: 1523270 Determination of polyunsaturated fatty acids CHEMBRO HOLDINGS (PTY) Ltd 27 June 1977 [1 July 1976] 26785/77 Heading G1B Polyunsaturated fatty acid levels in a body fluid are determined using a reagent comprising a 0À1 to 2 molar borate buffer pH 7 to 10 which contains an oxygenese enzyme which is specific for polyunsaturated fatty acids containing a cis, cis - 1, 4-pentadiene system, for example lipo-oxygenase, the free acids or their salts being oxidized with molecular oxygen in the presence of the reagent and the amount of oxygen consumed being measured using an oxygen electrode. Linoleic acid in absolute alcohol solution may be used as-a standard.
[GB1523270A]
Patent IE-32508-L (IE)
Title: Detergent compositions containing stabilised enzyme
IPC: C11D3/386
Filed: 1968-11-27
Abstract: 1,242,597. Proteolytic enzyme-containing detergent composition. PROCTER & GAMBLE CO. 26 Nov., 1968 [29 Nov., 1967; 27 Aug.. 1968], No. 66044/68. Heading C5D. A granular proteolytic enzyme-containing detergent composition comprises, by weight: (1) from 60 to 98% of a mixture of an organic detergent and an alkaline builder salt in a weight ratio of alkaline builder salt to organic detergent of 30:1-1:4; (2) from 0À001 to 2% of a proteolytic enzyme having enzymatic activity in the pH range 5- 12 and the temperature range 50-200 F.; and (3) a proteolytic enzyme-stabilizing amount of a partially hydrolysed and partially solubilized collagen having an average molecular weight of at least 5000. Specific examples of proteolytic enzymes suitable for use in the present invention are pepsin, trypsin, chymotrypsin, collagenase, keratinase, elastase, the subtilisins, papain, ficin, bromelin, carboxy peptidase, amino peptidase, aspergillopeptidase A and B and those proteolytic enzymes isolated from streptomyces species, e.g. Streptomyces griseus. The proteases may be utilized in the pure form or as powdered commercial enzyme compositions containing these enzymes in an amount 2-80% by weight, the balance being sodium or calcium sulphate. The partially hydrolysed and partially solubilized collagen preferably has an average molecular weight of 5000-250,000 and is suitably gelatin. Generally the collagen is used in a weight ratio of collagen to pure protease in the weight ratio 100:1-1:10, preferably 20:1-1:1. The organic detergents suitable for use in the composition include any of the conventional materials used in detergent compositions, viz. soap, anionic detergents, nonionic detergents, zwitterionic detergents, and ampholytic detergents. The alkaline builder salt may be a conventional inorganic or organic builder salt, e.g. alkali metal carbonates, phosphates and silicates, polyphosphonates, polyacetates and polycarboxylatcs. Preferred organic detergents include sodium alkyl benzene sulphonate, sodium alkyl sulphonate and mixtures thereof in which the alkyl groups contain 10-18 carbon atoms. The specific examples employ sodium tetrapropylene benzene sulphonate as detergent and a mixture of sodium tripolyphosphate and sodium silicate as the alkaline builder. The composition may also contain perfumes, anti-tarnishing agents, inert salts such as sodium sulphate, bacteriostatic agents, dyes, fluorescers, sodium perborate, dihydrogen disodium pyrophosphate, sodium bisulphate, sodium bicarbonate and sodium carboxymethylcellulose. In the preparation of the composition the enzyme and collagenderived protein is preferably mixed with water into a slurry or solution and subsequently sprayed on to one or more of the granular components comprising the detergent composition to provide enzyme-containing granules.
[GB1242597A]