baber/WOPTO huggingface dataset:
Patent CA-2464121-A1 (CA)
Title: Pregnancy-associated plasma protein-a2 (papp-a2)
Inventor: OXVIG CLAUS
IPC: A61K48/00
Filed: 2001-10-19
Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a new protein with homology to pregnancy-associated plasma protein-A (PAPP-A). We denote this protein PAPP-A2. The cDNA encoding PAPP-A2 was derived from human placenta. The present invention also provides for antisense molecules to the nucleotide sequences which encode PAPP-A2, expression vectors for the production of purified PAPP-A2, antibodies capable of binding specifically to PAPP-A2, hybridization probes or oligonucleotides for the detection of PAPP-A2-encoding nucleotide sequences, genetically engineered host cells for the expression of PAPP-A2, use of the protein to produce antibodies capable of binding specifically to the protein, methods for screening for pathologies in pregnant and non-pregnant patients that are based on detection of PAPP-A2 antigen in human body fluids or PAPP-A2-encoding nucleic acid molecules, use of the protein to screen for agents that alter the protease activity of PAPP-A2, use of the protein as a therapeutic target for such agents, and use of the protein as a therapeutic agent in relevant pathological states. Methods for screening for altered focal proliferation states in pregnant and/or non-pregnant patients, which include detecting levels of PAPP-A2, are also described. The present invention also provides the identification of a natural substrate of PAPP-A2, insulin-like growth factor binding protein (IGFBP)-5.
Patent CA-2465387-A1 (CA)
Title: A limited liability banking structure involving member bankiing and method of use
Inventor: DURBANO DOUGLAS M
IPC: G06Q40/02
Filed: 2004-04-28
Abstract: A limited liability banking structure and method of use, wherein individual depositors or customer/owners, collectively referred to as "members," may share in the profits and losses of the bank in order to stimulate deposits or capital raising, and still enjoy the benefits of limited individual liability and partnership taxation.  Various classes of members offer a variety of associated, but unique, benefits including the pass through of certain profits or tax losses. The banking entity profits are not taxed at the entity level, but only as such profits are passed through. to its various classes of members.
Patent CA-2465639-A1 (CA)
Inventor: SHICHIJO SHIGEKI
IPC: C07K7/06
Filed: 2002-10-29
Abstract: A gene which is recognized by HLA A2 restricted cytotoxic T lymphocytes (CTL) and/or induces CTL is isolated from a human glyoma cell line KNS60 cDNA  library and identified. Based on a tumor antigen encoded by the thus obtained gene, a peptide having the epitope of the tumor antigen is found out.
Patent CA-2469541-A1 (CA)
Inventor: TAKEDA TOMOHISA
IPC: F16K15/06
Filed: 2004-06-03
Abstract: A valve includes: a valve casing (1); a valve chamber (4) defined between a fluid inlet (2) and a fluid outlet (3) of the valve casing (1): and a plurality of check valve mechanisms (9) arranged in series within the valve chamber (4), the plurality of check valve mechanisms (9) each including: a valve seat (6) having a valve hole (5) formed therein: and a valve body (8) fixed to a valve shaft (7) and arranged on a fluid outlet (3) side of the valve seat (6), the valve shaft (7) passing through the valve hole (5) of the valve seat (6) and movably supported on a fluid inlet (2) side and the fluid outlet (3) side of the valve seat (6), the valve body (8) being adapted to move away from the valve seat (6) to open the valve hole (5) when applied with a fluid pressure from the fluid inlet (2) side and adapted to move toward and into contact the valve seat (6) to close the valve hole (5) when applied with a fluid pressure from the fluid outlet (3) side. As a result, a valve with a check valve mechanism capable of reliably preventing fluid backflow can be obtained.
Patent CA-2470251-A1 (CA)
Title: Process for manufacturing a cellulosic paper product exhibiting reduced malodor
Inventor: SPENCE TAMEKA
IPC: D21H17/66
Filed: 2002-12-10
Abstract: A process for manufacturing a cellulosic paper product is provided. The process comprises forming an aqueous suspension of papermaking fibers;  introducing sodium bicarbonate into the aqueous suspension; depositing the aqueous suspension onto a sheet-forming fabric to form a wet web; and dewatering and drying the wet web. The process of the present invention provides cellulosic paper products exhibiting a reduced malodor upon re-wetting.
Patent CA-2479122-A1 (CA)
Title: Procede et appareil servant a reduire l'interference entre les canaux dans un systeme de communication sans fil utilisant un entrelaceur non periodique
Inventor: WILLENEGGER SERGE
IPC: H04B1/707
Filed: 2003-03-13
Abstract: Cette invention porte sur un procédé et un appareil servant à réduire l'interférence dans un système de communication sans fil lorsque la source d'interférence est un composant déterminé du système. Dans un mode de réalisation, le récepteur pondère les émetteurs en fonction du moment où la source d'interférence est envoyée. En outre, l'émetteur peut recourir à une amplification de puissance pour atténuer l'effet de la source d'interférence. Dans un mode de réalisation, un système AMCR large bande envoie un canal de synchronisation conjointement à des canaux physiques, lequel canal de synchronisation n'est pas orthogonal aux canaux physiques. Le récepteur peut annuler le canal de synchronisation lorsqu'il reçoit des informations de commande ou de données. De même, le récepteur peut pondérer les émissions provenant de multiples émetteurs.
Patent CA-2479797-A1 (CA)
Inventor: BENSON RICHARD W
IPC: A23G9/32
Filed: 2003-03-18
Abstract: The present invention is directed to a packaged frozen product, comprising ( a) an edible frozen matrix, and (b) a fat based ganache coating comprising a compound coating, an edible oil, and water that is applied to at least one surface of the edible frozen matrix, wherein the fat based ganache coating h as a penetration hardness at -5 ~C of from about 4,400 to about 12,000 grams of force.
Patent CA-2484936-A1 (CA)
Inventor: GHOSH MANUKA
IPC: C12N5/071
Filed: 2003-05-07
Abstract: Substituted imidazolylmethyl pyridine and pyrazine derivatives that bind to GABAA receptors are provided. Such compounds may be used to modulate ligand binding to GABAA receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s).  Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAA receptors (e.g., receptor localization studies).
Patent CA-2486019-A1 (CA)
Title: Rigid reclosable bacon package
Inventor: SCHUETTE JOHN C
IPC: B65D85/72
Filed: 2004-10-28
Abstract: A reclosable package is provided for packaging and displaying a shingled stack of sliced bacon or other foodstuff in a highly visible manner, including a generally rigid tray member for receiving the bacon and a generally rigid cover member, at least one of which is transparent.
Patent CA-2486940-A1 (CA)
Title: .beta.-crystalline polypropylenes
Inventor: HOFFMANN KURT
IPC: D01F6/46
Filed: 2003-05-22
Abstract: A composition containing (1) a crystalline polypropylene resin and (2) one or more .szlig.-nucleating agents of the formula (I), wherein R1, R2 and R3, independently of one another, are C1-C20alkyl, C2-Calkyl substituted by C1-C,1oalkylamino, di(C1-C1oalkyl)amino, C1-Cloalkyloxy or hydroxy; C3-C2oalkenyl, C5-C12cycloalkyl, C5-C12Cycloalkyl substituted by 1, 2 or 3 C1-C10alkyl; cyclohexylmethyl; cyclohexylmethyl substituted by 1, 2 or 3 C1-C1oalkyl; C5-C9cycloalkenyl, C5-C9cycloalkenyl substituted by 1, 2 or 3 C1-C10alkyl; phenyl substituted by 1, 2 or 3 radicals selected from the group consisting of C1-C10-oalkyl, C1-C10alkyloxy, hydroxy, halogen, trihalogenmethyl, trihalogenmethoxy, benzoyl, phenylamino, acylamino and phenylazo; C7-C9phenylalkyl, C7-C9phenylalkyl which is substituted on the phenyl by 1, 2 or 3 radicals selected from the group consisting of C1-Cloalkyl, C1-C10alkoxy and hydroxy; naphthyl, naphthyl substituted by C1C1oalkyl, adamantyl, or a 5 to 6 membered heterocyclic group; characterized in that the polypropylene resin has a content of .szlig.-form crystals of at least 10 % calculated by means of the following equation .szlig.-form crystal content (%) = 100 x P.szlig.1,/(Pa1 + Pa2 + Pa3 + P.szlig.1) where Pa1 to Pa3 are respective peak heights (maxima) of the a-form and P.szlig.1 is a peak height (maximum) of the .szlig.-form determined by wide angle X-ray scattering.
Patent CA-2491244-A1 (CA)
Inventor: COFFY JEAN-HARAM
IPC: G07B17/00
Filed: 2003-06-30
Abstract: A method and system for processing postage payments is described. In one configuration a digital pen is utilized to provide a mail piece identifier. The data provided is utilized to account for postage and verify payment of postage.
Patent CA-2492030-A1 (CA)
Title: Method and kit for interpositional arthroplasty
Inventor: BUSCEMI PAUL J
IPC: A61B17/88
Filed: 2003-07-10
Abstract: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partiall y or fully preformed components adapted for insertion and placement into the body and at the joint site. The system includes a method and related components and/or devices in the form of a kit that can be used to provide o r perform some or all of the steps of: a) preparing a joint to receive an implant, b) determining an appropriate implant size for a particular joint, c) determining an appropriate implant thickness, d) inserting the implant into the joint, and/or e) securing the implant within the joint to a desired extent. One or more of the various components and devices, including optionally one or more implants themselves, can be provided or packaged separately or in varying desired combinations and subcombinations to provide a kit of this invention. In turn, a kit can include, or be used in combination with, one or more corresponding devices or components that will already exis t in the surgical suite, and that can optionally be sterilized for re-use in subsequent procedures. The selection and use of components, devices and/or implants within a kit of this invention is facilitated by the coordination o f various features in the manner described, including appearance, size and configuration.
Patent CA-2493552-A1 (CA)
Title: Device for simultaneously casing a hole while drilling
Inventor: MINSHULL RONALD G
IPC: E21B1/02
Filed: 2003-07-17
Abstract: A driving device for installing a pipe or casing, without the use of hydraulic or pneumatic means, by capturing the rotational motion of the drill string.  The driving device is placed at the top end of the pipe being (42) installed and the drill string (2) passes through the center of the device. The drill string freely rotates, advances or retracts within the driving device, until the driving device is attached (4) to the drill string when required. When the driving device is attached to the drill string, the rotational force of the drill string and any downward force applied to the drill string are captured, and used to install the pipe. The driving device uses the rotation of the drill string to impact a blow to the pipe, driving the pipe downward. The driving device uses any downward force applied to the drill string to maintain downward pressure on the pipe.
Patent CA-2495701-A1 (CA)
Inventor: TANAKA RYO
IPC: A44B19/08
Filed: 2005-02-01
Abstract: The invention provides a waterproof slide fastener and a manufacturing apparatus thereof, wherein each fastener element has a coupling head, a neck portion, a body portion, and leg portions which are continuously fused and integrated, a terminal end is projected from a gap between upper/lower half portions of the coupling head, upper/lower flanges of a slider make a sliding contact with a surface of each of upper/lower half portions of each leg portion, each half portion of the leg portion extending from the body portion via a crotch portion and guiding the flanges, two or more leg portions are disposed with a predetermined interval in a sliding direction, an entire shoulder width of a shoulder portion is larger than a body width of the body portion if it is provided, thereby intensifying fixing strength between a fastener tape and fastener elements and waterproofness, and allowing a smooth sliding of a slider.
Patent CA-2498003-A1 (CA)
Inventor: PHELPS BRUCE
IPC: G01N21/64
Filed: 2003-09-05
Abstract: Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also described.
Patent CA-2498102-A1 (CA)
Title: Testing of pressure sensor in surgical cassette
Inventor: MORGAN MICHAEL D
IPC: A61M1/00
Filed: 2003-08-18
Abstract: A method of determining the accuracy of a pressure sensor in a surgical cassette is disclosed. The method involves displacing a diaphragm of the sensor a pre-defined amount of displacement, and measuring the force exerted on the diaphragm by the displacing step. The accuracy of the pressure sensor is determined by comparing the force measured in the measuring step to a pre-defined force for the pre-defined amount of displacement.
Patent CA-2500007-A1 (CA)
Title: Method and device for removing lead sulfate film formed in lead-acid battery
Inventor: OKUNO SHIGEO
IPC: H02J7/00
Filed: 2003-09-17
Abstract: A novel device for removing a lead sulfate film formed on an electrode by decomposing the film into a particulate state without causing the film to come off or float, thereby recovering the performance of the lead-acid battery and prolonging the life. The electrodes of the battery are not damaged and noise is not produced externally. The device is attached to a lead-acid battery to remove the lead sulfate film formed by sulfation on an electrode of the battery. The device comprises a voltage sensor, a reference voltage generator, a voltage comparator, an operation/nonoperation switch, an oscillator, an amplifier, a waveform shaping circuit, a negative pulse current generator, and power-on indicator. A pulse current with a short pulse width causing a skin effect is outputted and thereby the surface portion of the film is concentratedly decomposed. The pulse width of the pulse current is preferably 1 microsecond or less.
Patent CA-2501581-A1 (CA)
Inventor: SMIDER VAUGHN
IPC: C07K16/22
Filed: 2003-10-09
Abstract: The present invention provides a recombinant catalytic polypeptide for cleaving a target protein, the nucleic acid encoding the recombinant catalyt ic polypeptide, a cell hosting the nucleic acid encoding the recombinant catalytic polypeptide, and a non-human transgenic mammal that is capable of producing a heterologous antibody with proteolytic activity. The invention also provides methods of cleaving a target protein using the recombinant catalytic polypeptides both in vitro and in vivo. The invention further provides a library of recombinant catalytic polypeptides with altered enzymatic activity and a method to alter enzymatic activity of the recombina nt catalytic polypeptides.
Patent CA-2504194-A1 (CA)
Inventor: JOYNER KENNY L
IPC: B43L13/00
Filed: 2005-04-18
Abstract: A method and apparatus for substantially lifting erasable marked images (4 ) from a marking surface (2) includes a rolled transparent adhesive film sheet (8) for lifting the image. A rolled paper sheet (8) having a shade or color that is contrasting to the image (4) allowing for clearer viewing and easy handling of the lifted image when the sheets (8,8) are adhered together. The sheet rolls (24,26) are positioned in an elongated handling unit (12,36) that enables dispensing and joining of the sheets (6,8). An urging slit (16) is formed on the unit to urge consistent adherence together of the two sheets (6,8) when pulled through. At least one suction cup (30) is connected to a side of the handling unit (12,38) in order to mount the apparatus (10,34) on or near the marked surface (2). Permanent mounting and motorized operation alternatives and a surface cleaning method are provided.
Patent CA-2505817-A1 (CA)
Inventor: NEMETH JOSHUA ROBERT
IPC: B42D15/10
Filed: 2003-11-14
Abstract: A laminated tamper evident security document (10) is provided which has a transparent or translucent support layer (12), first and second security layers (16, 16') on opposite sides of the support layer (12), first and second tamper evident layers (14, 14') between the support layer (12) and the security layers (16, 16') layers of printed information (22) over the security layers (16, 16') and polymeric outer layers (18). The security layers (16, 16') have security regions (26, 26') which together form a composite security device or image (30) to indicate an authentic security state. Upon exposure to predetermined conditions to delaminate the document, at least one of the tamper evident layers (14, 14') is arranged to destruct or otherwise affect at least one of the security layers (16, 16') to indicate an unauthentic state.  In one embodiment each of the tamper evident layers (14, 14') are formed from a weakly coherent or adherent material having a glass transition temperature lower than that of the other layers so that the tamper evident layer (14) separates a portion of the document containing one of the security layers (16) from the remainder of the security document (10) containing the other security document.
Patent CA-2506386-A1 (CA)
Inventor: OHIER ANDRE
IPC: F16L55/28
Filed: 2005-05-05
Abstract: The invention relates to a device intended to be introduced into a pipeline (1) for circulating a fluid and comprising an operational element (2), a central connecting rod (6) and a plurality of radial lugs (3), these lugs being linked to the operational element (2) by means of the connecting rod (6) and extending, under the effect of an elastic force, like umbrella spokes, to press against the inside of the pipeline (1).      According to the invention, the lugs (3) are spaced regularly around a same fitting (4), and the elastic force is at least partly constituted of a turning torque applied to the lugs through support means (5) constituted, for example, by an axial spring (52) pushing a stop washer (51) mounted to slide on the connecting rod (6).
Patent CA-2508151-A1 (CA)
Inventor: VOHRA ARUN
IPC: B08B7/02
Filed: 2005-05-25
Abstract: A device and process for cleaning electrical insulators mourned under an electrified contact rail parallel to a rail track comprises positioning arm(s) attached to a vehicle that travels on the track and a cleaning station with fixed or moveable fingers. The fingers have attached cleaning tools and engage, operate on, partly rotate around the circumference of the insulator, and disengage, as the vehicle passes by the insulator. The cleaning station can also ride on the contact rail and have moveable vertical members with cleaning tools attached to L-shaped tool holders that rotate around a portion of the circumference of the insulator. Cleaning tools include powered rotating, reciprocating, vibrating, oscillating and/or linear brushes, wrap-around cleaning belts, sonic horns, ultrasonic vibrating guns, lasers, pressure washing and/or water jetting nozzles on stationary, rotating or oscillating spray bars and spinning heads using steam, tap or deionized water, and pneumatic polishing nozzles.
Patent CA-2508315-A1 (CA)
Title: Aminoalkoxyindoles as 5-ht6-receptor ligands for the treatment of cns-disorders
Inventor: ZHAO SHU-HAI
IPC: A61K31/404
Filed: 2003-11-27
Abstract: The invention provides compound of the Formula (I) and pharmaceutically acceptable salts wherein R1, R2, R3, R4, m and n are as defined herein. The invention also provides methods for preparing, compositions comprising, and the use of compounds of formula (I) for the manufacture of a medicament for the treatment of 5-HT6 mediated diseases.
Patent CA-2510847-A1 (CA)
Title: Polymers with new sequence distributions
Inventor: SHAFFER TIMOTHY D
IPC: C08F8/00
Filed: 2003-12-19
Abstract: The invention relates to new polymerization processes including diluents including hydrofluorocarbons and their use to produce novel polymers with new sequence distributions. In particular, the invention relates to copolymers of an isoolefin, preferably isobutylene, and an alkylstyrene, preferably methylstyrene, even more preferably para-methylstyrene, with new sequence distributions. The copolymer may optionally be halogenated.
Patent CA-2513123-A1 (CA)
Inventor: LEWI PAULUS JOANNES
IPC: C07D253/06
Filed: 2004-02-05
Abstract: The present invention relates to HIV replication inhibitors of formula (I) as defined in the specification their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.
Patent CA-2514161-A1 (CA)
Title: A method and apparatus for measuring and controlling food intake of an individual
Inventor: DREHWING EDWARDS NANCY
IPC: G16H20/60
Filed: 2005-07-29
Abstract: Provided herein is a method for monitoring dietary intake of food items. The method involves the steps of selecting a portion of food, weighing the portion, inputting the type and weight amount of the food into a computer, and obtaining the caloric content of the food by from a database. There is also provided an apparatus for monitoring dietary intake of food items. The apparatus includes a means for weighing a preselected portion of food, a computer for inputting the type and weight amount of the food therein, and a database operatively associated with the computer for obtaining the caloric content of the food.
Patent CA-2515697-A1 (CA)
Title: Process for the production of 2-oxa-3-one androstane derivatives
Inventor: PONDER GARRATT W
IPC: C07D311/78
Filed: 2004-02-13
Abstract: The present invention relates to processes for the production of 2-oxa-3-one androstane derivatives. The processes comprise reacting a 3-one androstane derivative with ozone to form a 2-oxa-3-one androstane derivative.
Patent CA-2522150-A1 (CA)
Inventor: ANDERSON DAVID A
IPC: A61B1/005
Filed: 2004-03-31
Abstract: An electrically insulative layer of a shape memory alloy (SMA) actuator includes an inorganic material formed upon a portion of an SMA substrate. A  conductive material formed upon a portion of the electrically insulative layer in a trace pattern includes a first end, a second end, and a heating element disposed between the first and second ends. The SMA substrate is trained to deform at a transition temperature achieved when electricity is conducted through the conductive material via first and second interconnect pads terminating the first and second ends of the trace pattern.
Patent CA-2522957-A1 (CA)
Title: Compositions and methods for the therapy of inflammatory bowel disease
Inventor: KING DAVID
IPC: C07K16/28
Filed: 2004-04-23
Abstract: Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn~s Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR).