baber/WOPTO huggingface dataset:
Patent CA-3075461-A1 (CA)
Title: Composes de 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol utilises en tant qu'inhibiteurs de cdk
Inventor: BAHL ASH
IPC: C07D487/04
Filed: 2018-09-20
Abstract: La présente invention se rapporte d'une manière générale au domaine des composés thérapeutiques. Plus particulièrement, la présente invention concerne certaines composés de 4-[[(7-aminopyrazolo[1,5- a]pyrimidin-5-yl)amino]méthyl]pipéridin-3-ol (appelés dans la présente invention comme " composés APPAMP ") qui, entre autres, inhibent (par exemple de manière sélective) CDK (par exemple, CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, CDK10, CDK11, CDK12, CDK13, etc.). La présente invention concerne également des compositions pharmaceutiques comprenant ces composés, et l'utilisation de ces composés et de ces compositions, à la fois in vitro et in vivo, dans l'inhibition de CDK ; et dans le traitement de troubles comprenant : des troubles associés à CDK ; des troubles résultant d'une activité inappropriée d'une kinase dépendante de la cycline (CDK) ; des troubles associés à une mutation de CDK ; des troubles associés à une surexpression de CDK ; des troubles associés à l'activation en amont de la voie de CDK ; des troubles qui sont améliorés par l'inhibition de CDK ; des troubles prolifératifs ; le cancer ; des infections virales (y compris le VIH) ; des troubles neurodégénératifs (y compris la maladie d'Alzheimer et la maladie de Parkinson) ; l'ischémie ; des maladies rénales ; des troubles cardiovasculaires (y compris l'athérosclérose) ; et des troubles auto-immuns (y compris la polyarthrite rhumatoïde). Éventuellement, le traitement comprend également le traitement (par exemple, un traitement simultané ou séquentiel) par un principe actif supplémentaire, par exemple, un inhibiteur de l'aromatase, un anti-strogène, un agent de blocage de Her2, un agent chimiothérapique cytotoxique, etc.
Patent CA-3075695-A1 (CA)
Title: Aliment a grignoter a agregats sales
Inventor: SZCZUCINSKA MAJA
IPC: A23L29/206
Filed: 2018-09-26
Abstract: La présente invention concerne un produit alimentaire à grignoter comprenant une pluralité d'agrégats salés, chaque agrégat comprenant un mélange sec comprenant au moins une céréale, au moins une graine et au moins un fruit à coque, le mélange étant enrobé d'un liant, le liant comprenant ou étant constitué d'un mélange d'un composant de fibre alimentaire soluble et d'un sirop de sucre à faible équivalent en dextrose (DE), le sirop de sucre à faible équivalent en dextrose (DE) ayant un équivalent en dextrose (DE) maximal de 40, dans un rapport pondéral dans la plage allant de 30:70 à 70:30 et chaque agrégat comprenant de 65 à 85 % en poids du mélange et de 15 à 35 % en poids du liant, chaque valeur de % en poids étant sur la base du poids total de l'agrégat. Le produit alimentaire à grignoter fournit un en-cas satisfaisant entre les repas ou à la place d'un repas.
Patent CA-3077805-A1 (CA)
Inventor: GARNER MICHAEL S
IPC: A61L2/28
Filed: 2013-01-31
Abstract: A system and method for disinfecting hard surfaces in an area such as a hospital room including a light source emitting UV light and a reflector mounted behind the light source for concentrating and directing the light toward a target. The light source and reflector rotate to direct the concentrated beam around a room, thereby making more efficient use of the energy being emitted.
Patent CA-3079759-A1 (CA)
Inventor: SINGH KULBIR
IPC: C01G7/00
Filed: 2018-11-02
Abstract: A method for making metal nanorods comprises combining a source of metal cations with at least one surfactant to form a mixture, wherein the metal cations are reduced and the metal nanorods are produced. Metal nanorods produced by the method and uses thereof. The metal nanorods are useful in devices such as lateral flow devices.
Patent CA-3079870-A1 (CA)
Inventor: TONELLI WAYNE
IPC: B25J1/00
Filed: 2020-04-30
Abstract: Disclosed is a device for assisting in movement of a cylindrical body. The device has a curved band dimensioned to encircle a portion of the cylindrical body; two handles connected to the curved band; and attachment points provided at both ends of the curved band for connecting to a strap. The device disclosed herein allows for a cylinder to be moved without undue stress being on a user's back. Also disclosed are kits containing the device, as well as methods of using the device to move a cylindrical body.
Patent CA-3080321-A1 (CA)
Title: Composition comprising non-newtonian fluids for hydrophobic, oleophobic, and oleophilic coatings, and methods of using the same
Inventor: AHMAD SYED TAYMUR
IPC: C09D183/04
Filed: 2018-10-26
Abstract: A composition for forming a protective coating on an electronic device that is in the form of a non-Newtonian fluid that exhibits both viscous and elastic properties, and that forms at least one coating that is hydrophobic, oleophobic, or oleophilic is disclosed. The viscous and elastic properties associated with the non-Newtonian fluid allows the composition to redistribute after being applied as a coating an electronic device. Methods for protecting an electronic device from liquid contaminants by applying the disclosed composition and electronic devices comprising the composition are also disclosed. An electronic device, such as a printed circuit board, having a film made of the composition is also disclosed.
Patent CA-3080974-A1 (CA)
Inventor: JANG HAISHAN
IPC: A61K31/337
Filed: 2018-11-05
Abstract: The present invention relates to methods for modulating immune response based on binding I-domain of CD11b on the tumor associated myeloid cells (TAMCs) in the tumor microenvironment. Particularly, binding to I-domain of CD11b with anti-CD11b-I-domain antibody triggers immunostimulatory environment that have one or more of the following effects in the tumor microenvironment: increase the inflammatory cytokine in the tumor microenvironment, decrease the population of IDO+ myeloid suppresser cells, up-regulate M1 marker over M2 marker on the tumor associated macrophage, increase M1:M2 tumor associated macrophage ratio, promote differentiation of dendritic cells (DC), nature killer dendritic cells (NKDC), and plasmacytoid dendritic cells (pDC), increase population of 4-1BB+PD-1+ neoantigen specific CD8 T cells. Converting cold (non-inflamed) to hot (inflamed) tumor by binding to I-domain of CD11b with anti-CD11b-I-domain antibody allows enhanced effectiveness of immune response modulator.
Patent CA-3081399-A1 (CA)
Inventor: DONALD ALASTAIR
IPC: A61P31/12
Filed: 2018-11-02
Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
Patent CA-3081580-A1 (CA)
Inventor: OZOZLU AKIN
IPC: H04W92/18
Filed: 2018-11-14
Abstract: A battery-powered wireless communication device (110, 411, 511) has internal antennas (601-609, 701-702). In the wireless communication device (110, 411, 511), transceiver circuitry (111, 402, 502-503, 600) wirelessly receives external antenna data that indicates on/off status, reserve battery power, and geometric earth-orientation for the individual antennas in a different wireless communication device (120). Baseband circuitry (112, 401, 501) determines internal antenna data that indicates the on/off status, reserve battery power, and geometric earth-orientation for the internal antennas (601-609, 701-702). The baseband circuitry (112, 401, 501) executes a user application that generates and consumes user data. The baseband circuitry (112, 401, 501) selects a set of the internal antennas (601-609, 701-702) to serve the user application based on the internal antenna data and the external antenna data. The transceiver circuitry (111, 402, 502-503, 600) wirelessly exchanges the user data over the selected set of the internal antennas (601-609, 701-702).
Patent CA-3082061-A1 (CA)
Title: A galvannealed steel sheet
Inventor: ZAPICO ALVAREZ DAVID
IPC: C22C38/50
Filed: 2018-10-19
Abstract: The present invention relates to a method for the manufacture of a galvannealed steel sheet comprising the provision of a specific steel sheet, a recrystallization annealing, a hot-dip galvanizing and an alloying treatment; the galvannealed steel sheet and the use of said galvannealed steel sheet.
Patent CA-3082448-A1 (CA)
Title: Strigolactone derivatives
Inventor: ADNANI NAVID
IPC: C07D307/46
Filed: 2018-11-16
Abstract: The present disclosure relates to derivatives of strigolactone and formulations thereof. The present disclosure also relates to methods of treating a plant to improve, for example, the yield, growth, or vigor of a plant. The disclosed strigolactone derivatives and formulations may be combined with a plant growth regulator, a fertilizer, an insecticide, an herbicide, a fungicide, a urease inhibitor, a nitrification inhibitor, and/or an excipient.
Patent CA-3082789-A1 (CA)
Inventor: MORALES FLORES ALVARO E
IPC: E01F15/08
Filed: 2018-06-13
Abstract: Roadway barrier bicycle safety apparatus for attachment to an upper portion of a roadway barrier segment for topping the upper portion to prevent a bicycle from extending over the upper portion. The apparatus includes a shell having a curved upper surface and configured to prevent snagging of a bicycle or bicycle rider.
Patent CA-3083865-A1 (CA)
Inventor: KALFA YONAH
IPC: A63B69/38
Filed: 2018-08-22
Abstract: A carrying bag for sports equipment comprises compartments suitable to accommodate sports equipment; and an automatic launching apparatus configured to launch sports balls to a distance from the bag.
Patent CA-3084852-A1 (CA)
Title: Wireless communication method and device
Inventor: XIAO FANGYING
IPC: H04W28/04
Filed: 2018-12-07
Abstract: The present disclosure provides a method executed by a user equipment unit. The method comprises: a transmitting side of an Acknowledged Mode Radio Link Control (AM RLC) entity delivering an Acknowledged Mode Data Protocol Data Unit (AMD PDU) containing a query to a lower layer. The method further comprises: an RLC entity updating a send state variable of the query to the largest sequence number of an Acknowledged Mode Radio Link Control Service Data Unit (RLC SDU) that has already been transmitted and is waiting to be acknowledged. The present disclosure further provides a corresponding user equipment unit.
Patent CA-3084910-A1 (CA)
Title: High density mobile plant cultivation system
Inventor: KRAUSE SEAN
IPC: A01G9/20
Filed: 2020-06-25
Abstract: ABSTRACT A plant cultivation system that includes a plurality of mobile racks and a plurality of lighting assemblies that are movable relative to each other. The mobile racks are designed to be independently movable along a floor surface and each support a plurality of planting units designed to receive the plants. The lighting assemblies are positioned adjacent to the mobile racks and are supported along an overhead lighting track independent from the mobile racks.  Each of the lighting assemblies is movable along a rail of the overhead lighting track to adjust the position of the lighting assemblies relative to the mobile racks. The lighting assemblies are designed such that the mobile racks contact the lighting assemblies to move the lighting assemblies along the lighting track. Each lighting assembly includes one or more lighting fixtures that are operable to provide the required light for growing plants supported on the mobile rack. Date Recue/Date Received 2020-06-25
Patent CA-3087112-A1 (CA)
Inventor: JENKINS BRAD
IPC: B25B23/142
Filed: 2019-01-03
Abstract: L'invention concerne un mécanisme de déclenchement (10, 110, 210, 310, 410) pour un outil de couple (12, 112, 212, 312, 412) à déclenchement électronique permettant de serrer une vis ou analogue, qui se déclenche lors d'un un couple de consigne. Le mécanisme de déclenchement (10, 110, 210, 310, 410) comprend un corps d'entraînement (16, 118, 218, 318, 418) et un corps de base (14, 114, 214, 314, 420), qui tournent, pour transmettre un couple, autour d'un axe commun. Un mécanisme de verrouillage (30, 150, 219, 320, 414) couple ainsi le corps d'entraînement (16, 118, 218, 318, 418) et le corps de base (14, 114, 214, 314, 420) pour transmettre l'un à l'autre un couple. Des moyens de détection et d'évaluation permettent de détecter et d'évaluer le couple transmis sont prévus, un émetteur de signal, lorsqu'un couple de consigne est atteint, actionnant le mécanisme de verrouillage (30, 150, 219, 320, 414) pour découpler le corps d'entraînement (16, 118, 218, 318, 418) du corps de base (14, 114, 214, 314, 420).
Patent CA-3088472-A1 (CA)
Inventor: HUNTER TIMOTHY
IPC: D07B1/02
Filed: 2019-02-12
Abstract: A synthetic rope (20) comprises a core (22) and at least a first layer surrounding the core (22). The first layer has first layer strands (26). The core has a fluted outer surface with spaced apart helical concave grooves. Each of these grooves contacts one of the first layer strands (26). The grooves have a radius of curvature (24) that is greater than the radius of curvature (14) of a circle having a same diameter as the contacting first layer strand before twisting.
Patent CA-3089960-A1 (CA)
Title: Method for transmitting he-ltf sequence and apparatus
Inventor: XUE XIN
IPC: H04W28/18
Filed: 2016-08-26
Abstract: ABSTRACT Embodiments of the present invention provide method and apparatus for sending and receiving data in a wireless local area network. A sending apparatus obtains an HE-LTF sequence corresponding to a transmission bandwidth, maps a sequence segment to subcarriers in a resource block unit (RU) allocated to a station and sends the sequence segment. A receiving apparatus obtains an HE-LTF sequence corresponding to a transmission bandwidth, determines a sequence segment as reference sequence for channel estimation. The sequence segment is in the HE-LTF sequence and is determined according to a size and a location of the RU. The sending apparatus or the receiving apparatus may be an access point or a station. 2x and 4x sequences in different transmission bandwidth with low PARR are provided. Date Recue/Date Received 2020-08-13
Patent CA-3091236-A1 (CA)
Inventor: DU WENMIN
IPC: A61K47/36
Filed: 2020-08-26
Abstract: A method for preparing, from one or more dried traditional-Chinese-medicine materials in non-powder forms, instant traditional-Chinese-medicine dried powder for decoction. The method has the steps of: adding one or more first edible excipients to the one or more dried traditional-Chinese-medicine materials; and grinding the mixture of the one or more first edible excipients and the one or more dried traditional-Chinese-medicine materials to powder with sizes of a predefined range to obtain the instant traditional-Chinese-medicine dried powder. In this method, the one or more first edible excipients are added to the one or more dried traditional-Chinese-medicine materials before or during said grinding. In various embodiments, the edible excipients may be dextrin, glutinous-rice powder, rice powder, and starch. The instant traditional-Chinese-medicine dried powder may be packaged into sealed tea bags or gauze bags for long-term storage up to five years and for convenient taking.
Patent CA-3091356-A1 (CA)
Inventor: PANUSOPONE KRIT
IPC: H04N19/543
Filed: 2019-02-15
Abstract: La présente invention concerne un système et un procédé de codage inter mettant en uvre une mise en correspondance entre des modèles de taille variable. Un modèle supérieur, un modèle gauche et un modèle supérieur-gauche peuvent être définis. La largeur du modèle supérieur est égale à la largeur du bloc de codage, la hauteur du modèle gauche est égale à la hauteur du bloc de codage, mais les secondes dimensions (hauteur et largeur) des modèles sont variables. Une meilleure correspondance au sein du bloc de codage actuel est ensuite identifiée et le bloc de codage est alors codé par mise en uvre d'une FRUC.
Patent CA-3092194-A1 (CA)
Title: Water pipe smoking system
Inventor: LEE SANDRA
IPC: A24F1/30
Filed: 2020-08-31
Abstract: A water pipe including a water chamber that has a threaded top portion with a first opening into the water chamber, wherein the threaded top portion is configured to removably couple to a cap. The water pipe also includes a tube and a percolator disposed within the water chamber. A first end of the tube is coupled to a wall of the water chamber to form a second opening in the water chamber which extends into a first end of the tube, and a second end of the tube is coupled to the percolator.
Patent CA-3092693-A1 (CA)
Inventor: DEMUTH PETER C
IPC: A61K31/70
Filed: 2019-03-01
Abstract: The invention provides compounds including a CpG oligodeoxynucleotide sequence linked to a lipid by a linker and related compositions and methods. The invention features a compound consisting of the nucleotide sequence of SEQ ID NO:1, at its 5' end, bonded or linked by a linker to a lipid. Further, the invention features a method of treating a cancer in a human patient, comprising administering to the patient the compound. Further, the invention features a pharmaceutical composition including the compound and a pharmaceutically acceptable carrier. The invention features a kit including (I) the compound or a composition comprising the compound; and (ii) a protein comprising SEQ ID NO:2 or SEQ ID NO:3.
Patent CA-3093030-A1 (CA)
Title: Strip containing acaricide
Inventor: CHICON CARNERO JOSE PAULINO
IPC: A01K47/06
Filed: 2019-03-05
Abstract: The invention relates to a strip containing acaricide, which is made up of a plurality of compartments, placed in parallel and connected to one another, which serve to house an acaricide substance, in semi-solid state, characterised in that the tube-shaped compartments are square, rectangular, cylindrical, hexagonal or of any other geometric shape on the inside, and the inlet is open at both ends, the smaller inlet having an opening of 5 mm; an acaricide substance which acts by contact is deposited inside of same; the containing strip has a length of 10 mm to 500 mm, a width of 10 mm to 400 mm, and a height of 1 mm to 5 mm, all inclusive.
Patent CA-3097118-A1 (CA)
Title: Methods of detecting amino acid deficiencies
Inventor: SIRR AMY
IPC: C12N15/09
Filed: 2019-04-16
Abstract: The present application relates to a method of screening a subject (and/or treating a subject) for a disease. The application further relates to cells and kits for determination of a disease. Also contemplated are treatments, including those based on a personalized cell model system that determines a subject's threshold for a disease and their personalized treatment.
Patent CA-3100351-A1 (CA)
Inventor: LIN TERRY KANG
IPC: B60N2/58
Filed: 2019-05-14
Abstract: The present disclosure provides for a protective covering, which includes a cover portion, an elongated piece of fabric, a first coupling mechanism, and a second coupling mechanism. The cover portion is for a seat cushion. The elongated piece of fabric extends from the cover portion. The first coupling mechanism couples the cover portion to a first end of the elongated piece of fabric. The second coupling mechanism is configured to couple the cover portion to a second end of the elongated piece of fabric.
Patent CA-3100419-A1 (CA)
Title: Storage and transport box
Inventor: GRIFFEROS REYES PABLO IGNACIO
IPC: B65D43/00
Filed: 2018-04-20
Abstract: The present invention relates to a wall-lid reinforcement system for the reinforcement of a box for storing and/or transporting goods wherein the box comprises a base body formed by side walls and a bottom wall, each one comprising inner and outer faces wherein the inner faces define an inner space with an opening; and a lid with an inner face, an outer face and a peripheral edge to close the opening of the base body and to define a closed configuration of the box. The wall-lid reinforcement system comprises at least one wall reinforcement body arranged on at least one face of at least one side wall of the base body of the box wherein said wall reinforcement body comprises a wall support area arranged towards the opening of the base body; and at least one lid reinforcement body arranged on the inner face of the lid, wherein the lid reinforcement body comprises a lid support area that faces the wall support area when the box is closed; wherein the wall reinforcement body and the lid reinforcement body define at least one reinforcement assembly. Furthermore, the invention relates to a box for storage and/or transport of goods.
Patent CA-3100700-A1 (CA)
Inventor: SARRAF STELLA
IPC: G01N33/68
Filed: 2019-05-31
Abstract: La présente invention concerne de manière générale des compositions et des procédés pour déterminer si un patient souffre d'Une lésion cérébrale traumatique (TBI) par détection de la présence d'une protéine bêta amyloïde dans un oeil du patient. L'invention concerne également des compositions et des procédés de préparation d'un patient pour le diagnostic et le traitement d'une lésion cérébrale traumatique (TBI).
Patent CA-3103995-A1 (CA)
Inventor: WARNER STEVEN L
IPC: C07D401/12
Filed: 2019-07-26
Abstract: L'invention concerne des procédés de traitement d'une maladie chez un sujet qui en a besoin par l'administration d'un inhibiteur d'ACVR1 présentant la formule suivante (I) : (I), comprenant les stéréoisomères, les tautomères, les sels pharmaceutiquement acceptables et les promédicaments correspondants, dans laquelle R1, R2, R3 et R4 sont tels que définis dans la description. Les sujets qui peuvent bénéficier d'un traitement peuvent présenter des mutations dans leur gène ACVR1. Diverses maladies peuvent être traitées à l'aide des procédés décrits, y compris des cancers (par exemple le gliome pontique intrinsèque diffus (DIPG)) et des troubles génétiques (par exemple, la fibrodysplasie ossifiante progressive (FOP)).
Patent CA-3105411-A1 (CA)
Title: Substituted thiophenecarboxamides and analogues as antibacterials agents
Inventor: BERNIER DAVID
IPC: A01N43/28
Filed: 2019-07-03
Abstract: The present disclosure relates to substituted thiophene carboxamides and analogues thereof of formula (II) that may be used for protecting plants from bacterial diseases, in particular from bacterial diseases caused by bacteria belonging to the genus Xanthomonas.
Patent CA-3106521-A1 (CA)
Title: Ensemble de chariot ferroviaire comportant des composants de barre en i
Inventor: WIKE PAUL STEVEN
IPC: B61F5/52
Filed: 2019-07-12
Abstract: La présente invention concerne un ensemble de chariot qui est configuré pour se déplacer le long d'une voie comportant des rails, et comprend un premier longeron, un deuxième longeron et une traverse s'étendant entre le premier longeron et le deuxième longeron. Un ou plusieurs éléments parmi le premier longeron, le deuxième longeron et la traverse comprend au moins une partie formée sous la forme d'une barre en I qui comprend une bande ayant une première extrémité et une deuxième extrémité opposée à la première extrémité, une première bride s'étendant depuis la première extrémité de la bande, et une deuxième bride s'étendant depuis la deuxième extrémité de la bande. Une épaisseur de la bande augmente depuis un premier axe neutre vers la première bride et la deuxième bride.