baber/WOPTO huggingface dataset:
Patent IL-67545-A0 (IL)
Title: Ergolinyl compounds and pharmaceutical compositions containing same
IPC: C07D457/12
Filed: 1982-12-22
Abstract: Ergolinyl compounds which are nitrogen-substituted in the 8-position and have Formula (I)and physiologically compatible salts thereof, wherein the 8-substituent can be in the a- or β-position andrepresents a single or a double bond. R<sup>2</sup> is hydrogen, C<sub>1-4</sub>-alkyl or C<sub>1-7</sub>-acyl, R<sup>3</sup> is hydrogen, chlorine or bromine, and R<sup>4</sup> is C<sub>2-6</sub>-alkyl, C<sub>3-6</sub>-cycloalkyl-C<sub>1-3</sub>-afkyl, C<sub>3-6</sub>-alkenyl, or C<sub>2-6</sub>-alkynyl;
Patent IL-72477-A0 (IL)
Title: Pyrrolidinone derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D205/08
Filed: 1984-07-20
Abstract: Compounds of the formula   <IMAGE>   wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms; and R2 is pyridyl, phenyl or mono-, di- or tri-substituted phenyl, where the substituents are alkyl of 1 to 2 carbon atoms, alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, nitro, benzyloxy or hydroxyl. The compounds are useful as nootropics.
Patent IL-75214-A0 (IL)
Title: Signal peptide for the excretion of peptides in streptomycetes
IPC: C12N15/00
Filed: 1985-05-16
Abstract: 1. Claims for the contracting states : BE. CH. LI. DE. FR. GB. IT. LU. NL. SE DNA sequence B, obtainable from Streptomyces tendae strains, which produce tendamistat and have preferably been treated with sublethal doses of acriflavine, by isolation of the complete DNA, digestion with Pst l, Southern hybridization with the DNA sequence A, 5'-(**32 P-)CCT TCA GTG TCG TCT TCG TA-3' (A) isolation of the 2.3 kb Pst l fragment, cutting with BamHl, Southern hybridization with the sequence A, isolation of the 0.94 kb Pst l-BamHl subfragment, cutting with Sau 3a, Southern hybridization with the sequence A, isolation of the 0.525 kb BamHi-Sau 3a subfragment and sequencing of the DNA, and which has the following features : a) it is located immediately upstream of the tendamistat structural gene, b) it codes at the amino terminal end for Met-Arg-Val-Arg-Ala-Leu-Arg, c) it codes at the carboxyl terminal end for Ala-Ser-Ala and d) it codes in the middle for a hydrophobic region X which comprises 10 to 25, preferably 17 to 20, amino acids. 1. Claims for contracting state AT A process for the preparation of polypeptides composed of genetically codable amino acids, characterized by the expression, in a host cell of the genus Streptomyces, of a gene structure which contains in the reading frame with the structural gene for the desired polypeptide the DNA sequence B of a prepeptide, which sequence is obtainable from Streptomyces tendae strains, which produce tendamistat and have preferably been treated with sublethal doses of acriflavine, by isolation of the complete DNA, digestion with Pst l, Southern hybridization with the DNA sequence A, 5'-(**32 P-)CCT TCA GTG TCG TCT TCG TA-3' (A) isolation of the 2.3 kb Pst l fragment, cutting with BamHI, Southern hybridization with the sequence A, isolation of the 0.94 kb Pst l-BamHl subfragment, cutting with Sau 3a, Southern hybriridization with the sequence A, isolation of the 0.525 kb BamHl-Sau 3a subfragment and sequencing of the DNA, and a) is located immediately upstream of the structural gene, b) codes at the amino terminal end for Met-Arg-Val-Arg-Ala-Leu-Arg, c) codes at the carboxyl terminal end for Ala-Ser-Ala and d) codes in the middle for a hydrophobic region X which comprises 10 to 25 amino acids.
Patent IL-96346-A0 (IL)
Title: Method for the preparation and purification of a mixture of glycosphingolipids free from contamination by non-conventional viruses
IPC: C07H15/10
Filed: 1990-11-14
Abstract: The process of the invention relates to a process for the preparation of a ganglioside mixture, free from contaminants associated with non-conventional, life-threatening viruses, without altering the biological and pharmacological characteristics of the mixture on the central and peripheral nervous systems.
Patent AU-PR296201-A0 (AU)
Title: Angularly adjustable coupling
IPC: B62B9/20
Filed: 2001-02-09
Abstract: A pivotal coupling has plastics components (20, 30) with mutually engageable toothed parts (24, 34) to maintain them in a number of angular relationships. Components (20, 30) also include sockets or plugs (22, 32) to engage tubes (12, 14). In the event of structural failure of plastics components (20, 30) the coupling will still be held together by further hinge (70) having steel plates (72-73) inset into components (20, 30) and attached both to them and to tubes (12, 14). The coupling is useful for adjustable handles of prams or strollers where climatic extremes of heat or cold may lead to embrittlement of plastics components and their sudden failure.
Patent FI-20020355-A0 (FI)
Inventor: LEFEVRE DIDIER
IPC: C12Q1/06
Filed: 2002-02-22
Abstract: The invention relates to a reagent and a process for the identification and counting of biological cells in a sample. This reagent comprises a cell lysing agent selected from at least one detergent in a concentration capable of specifically lysing a given type of cells in the sample, and a stain capable of marking the intracellular nucleic acids of the remaining unlysed cells. Application in particular for the identification and counting of cells using an automated analysis system based on flow cytometry.
Patent IL-102463-A0 (IL)
Title: Laser scanning appartus
IPC: G02B26/10
Filed: 1992-07-10
Abstract: Laser scanning apparatus includes a machine frame (2), a first supporting member (4) for supporting a working medium, and a second supporting member (6) for supporting at least the delivery end of a laser beam delivery system. One of the supporting members, preferably the latter one, is a movable carriage mounted in cantilever fashion from one side of the machine frame for effecting relative movement between the working medium and the laser beam delivery system to cause the laser beam to scan the working medium. <IMAGE>
Patent IL-108061-A0 (IL)
Title: Inhaler for powderded medications
IPC: B65B7/14
Filed: 1993-12-17
Abstract: PCT No. PCT/US93/12076 Sec. 371 Date Jun. 1, 1995 Sec. 102(e) Date Jun. 1, 1995 PCT Filed Dec. 16, 1993 PCT Pub. No. WO94/14492 PCT Pub. Date Jul. 7, 1994A powder inhaler comprising: a powder housing for holding a supply of powdered material to be dispensed and a metering plate for holding a metered amount of said powdered material, the metering plate being alternately positionable below said supply of powdered material or within an inhalation conduit, by means of a bi-directional, angle-limited relative rotation about a common central axis; a counter for providing a visual count of the number of doses of said powdered material that have been dispensed or remain to be dispensed in response to the relative rotation, the counter including: a continuous counter ring and a coaxially mounted intermittent counter ring, both rings being mounted on a base in surrounding relation to a retaining post, being rotatable about the common central axis and having counting indicia thereon for displaying said visual count; and a display means through which at least one of the counting indicia is displayed to indicate a count corresponding to a number of doses of powdered material that have been dispensed or remain to be dispensed.
Patent IL-110551-A0 (IL)
Title: Methods for b-cell population control
IPC: A61K38/00
Filed: 1994-08-02
Abstract: Methods are provided for inducing cell death in B-cells, including neoplastic B-cells, by employing reagents that bind to a B-cell epitope. Particularly, antibodies specific for the marker can be administered to a host to induce death in B-cells to which the antibodies bind or can be used in ex vivo clinical situations to selectively remove B-cells. A B-cell specific oligosaccharide epitope useful as a B-cell marker has been identified. The ligand being recognized on B lymphocytes has no apparent similarities to any of the known pan-B cells markers. In addition, proteins which specifically bind the disclosed epitope are provided. Human monoclonal antibody 216, which recognizes this B-cell epitope, is cytotoxic to B-cells and binds all CD19+ and CD20+ B lymphocytes in human peripheral blood and spleen. Furthermore, MAb 216 does not distinguish B cells by the isotype expressed, binding IgG+ and IgM+ cells with equal intensity, and also bind all B cells regardless of their CD5 expression. Methods to inhibit neoplastic B-cell growth by administering a B-cell-cytotoxic protein are presented. These products and methods find use in diagnosis and therapy.
Patent IL-123551-A0 (IL)
Title: Tricyclic erythromycin derivatives
IPC: A61K31/70
Filed: 1996-10-17
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R<1>, R<2> and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.
Patent IL-139417-A0 (IL)
Title: Process for removing water from fibrous web using oscillatory-flow-reversing impingement gas
IPC: D21F5/18
Filed: 1999-06-29
Abstract: A process and an apparatus for removing water from a fibrous web are disclosed. The process comprises providing a fibrous web having a moisture content from about 1% to about 99%; providing an oscillatory flow-reversing impingement gas having a pre-determined frequency; providing a gas-distributing system comprising at least one discharge outlet designed to emit the oscillatory flow-reversing impingement gas onto the web; and impinging the oscillatory flow-reversing gas onto the web through the plurality of discharge outlets, thereby removing moisture from the web.The apparatus comprises a web support designed to receive a fibrous web thereon and to carry it in a machine direction; at least one rotary valve pulse generator designed to produce oscillatory flow-reversing air or gas; and at least one gas-distributing system in fluid communication with the pulse generator for delivering the oscillatory flow-reversing air or gas to the web. The gas-distributing system terminates with at least one discharge outlet juxtaposed with the web support such that the web support and the discharge outlets form an impingement distance therebetween.
Patent IL-146851-A0 (IL)
Title: 1- (4-sulfamylaryl)- 3- substituted -5-ayl-2-pyrazolines as inhibitors of cyclooxygenase-2
IPC: C07D231/06
Filed: 2000-06-16
Abstract: Compounds of the formula wherein: X is selected from the group consisting of trihalomethyl, C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl, and a group of formula II: wherein: R<SUB>3 </SUB>and R<SUB>4 </SUB>are independently selected from the group consisting of hydrogen; halogen; hydroxyl; nitro; C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl; C<SUB>1</SUB>-C<SUB>6 </SUB>alkoxy; carboxy; C<SUB>1</SUB>-C<SUB>6 </SUB>trihaloalkyl; and cyano; Z is selected from the group consisting of substituted and unsubstituted aryl; or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of cyclooxygenase-2 activity. They are useful for treating cyclooxygenase-mediated disorders, including, for example, inflamation, neoplastic disorders and angiogenesis-mediated disorders.
Patent IL-148313-A0 (IL)
Title: N-heterocyclic derivatives as nos inhibitors
IPC: A61P37/06
Filed: 2000-08-24
Abstract: N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.
Patent IL-150951-A0 (IL)
Title: Transgenic animal model for obesity expressing foxc2
IPC: G01N33/15
Filed: 2001-02-16
Abstract: According to the invention, a major role for the winged helix protein FOXC2 in regulating energy balance and adiposity is demonstrated. The invention relates to transgenic non-human mammalian animals being capable of expressing the human <i>FOXC2</i> gene in its adipose tissue. The invention also relates to methods for identifying compounds useful for the treatment of medical conditions related to obesity or diabetes, said compounds being capable of stimulating expression of the human <i>FOXC2</i> gene, or being capable of stimulating the biological activity of a polypeptide encoded by the human <i>FOXC2</i> gene. The invention further relates to methods for identifying compounds useful for the treatment of medical conditions related to malnutrition, said compounds being capable of decreasing expression of the human <i>FOXC2</i> gene, or being capable of decreasing the biological activity of a polypeptide encoded by the human <i>FOXC2</i> gene.
Patent IL-151569-A0 (IL)
Title: Device for visual identification of cables or conduits
Inventor: BRUNET PATRICE
IPC: G02B6/00
Filed: 2001-01-17
Abstract: The invention provides a device for accurately locating ends of cords, wires cables or conduits, in particular in the fields of electricity, electronics, telephone and computer. The device includes an optical fiber disposed on a cord and extending from a first end to a second end of the cord. The optical fiber includes a first fiber end disposed at the first end of the cord and a second fiber end disposed at the second end of the cord. The device further includes a means for injecting light disposed proximate the first fiber end, the first fiber end being accessible so as to be illuminated by the means for injecting light and the second fiber end being accessible so as to recover the light injected at the first fiber end. Said device is useful for locating computer switching cords.
Patent IL-155232-A0 (IL)
Title: Process for manufacturing polyamides
Inventor: HELFT MATTHIEU
IPC: B01J19/00
Filed: 2001-10-03
Abstract: The invention relates to a continuous process for manufacturing polyamides. The polyamides are of the type obtained from diacids and diamines. The process comprises an operation of continuous mixing of a compound which is rich in amine end groups and a compound which is rich in acid end groups and a polycondensation operation using the mixture. The invention relates to the starting phase of such a process, during which an aqueous solution comprising a mixture of monomers in substantially stoichiometric proportions is used.
Patent IL-157886-A0 (IL)
Title: Secure multicast transmission
IPC: H04W12/00
Filed: 2003-09-11
Abstract: A method of multicasting data. The method includes providing a data block for multicasting, generating a plurality of segments that represent the data block, such that a receiver needs to receive fewer than all the generated segments in order to reconstruct the data block, encrypting at least a portion of the generated segments, so as to generate encrypted data units encrypted with a plurality of different keys or encryption methods and transmitting the encrypted data units over one or more multicast channels.
Patent IL-164094-A0 (IL)
Title: Carboxyoic acid compounds and drugs containing thecompounds as the active ingredient
IPC: C07D265/36
Filed: 2003-03-06
Abstract: A carboxylic acid compound represented by formula (I): <CHEM> (meanings of the symbols in the formula are as mentioned in the specification) and a pharmaceutical agent comprising the compound. <??>Since the compound represented by formula (I) binds to a DP receptor and shows antagonistic activity for the DP receptor, it is useful for prevention and/or treatment of diseases such as allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, urticaria, eczema, diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like.
Patent IL-182204-A0 (IL)
Title: Method and system for providing a customized media list
IPC: H04N17/00
Filed: 2007-03-26
Abstract: A method and system is described for providing a customized media list to a user (240) over a data network (230). The method comprises providing personalized data (241) of the user (240) to a computer system, generating a customized media list by the computer system for the user (240) based on the personalized data (241), and providing the customized media list to the user (240) through the computer system where the customized media list represents a customized content and a customized advertising. A system is further disclosed and claimed for providing customized media list to a user (240) over a data network (230).
Patent RO-131330-A0 (RO)
Title: Road marking and floor marking compositions
Inventor: SPIREA-ANDREI RADU-ŞTEFAN
IPC: C09D11/10
Filed: 2016-04-01
Abstract: The invention relates to polyol resin compositions for polyurethane paints meant for road or floor markings, which contain at least one polyol and one filler, where the mass ratio between polyol and filler is from 1:3 to 1:8, to methods of preparation thereof, polyurethane paints for road and floor markings comprising the same, to methods of preparation and application of said paints and road and floor markings obtained therewith.
Patent ZM-1492-A1 (ZM)
Title: A method and apparatus for thickening fine particle suspensions
Inventor: BOGEN JAN ODD
IPC: B02C17/16
Filed: 1992-04-25
Abstract: The present invention relates to a method for finely-grinding minerals and similar material intended for use as filler material to a particle size appropriate for this purpose, with the aid of a mill which operates with agitated grinding medium and in which the material is ground in a substantially dry state. The invention is characterized by predetermining the stay time of the material being ground in the mill; maintaining the predetermined stay time partly by discharging ground material from the mill at a predetermined, essentially constant rate, and partly by adjusting the infeed of material to the mill in relation to the quantity of material discharged from the mill such that the amount of material present in the mill increases during the infeed of material thereto; and by interrupting the infeed of material to the mill over a predetermined short period of time when the material reaches a predetermined highest level in said mill. The invention also relates to an arrangement for carrying out the method. This arrangement is characterized in that it includes a first motor-driven device which functions to control the infeed of material, a mill for grinding with the aid of an agitated grinding medium, a perforated disc which functions to separate grinding medium from the ground material leaving the mill, a second motor-driven device which functions to maintain a substantially constant outfeed of ground material from the mill, and a level monitor which is mounted in the upper part of the mill and connected to the motor-driven infeed device. <IMAGE>
Patent CU-21729-A1 (CU)
Title: Biopila para equipos electricos y electronicos
Inventor: ROSALES BREESLER BRUNO EVANS
IPC: H01M6/06
Filed: 1985-07-05
Abstract: Esta invención está relacionada con el campo de la energía eléctrica para la alimentación de equipos electrónicos y eléctricos. El objetivo perseguido consiste en lograr una pila de larga duración almacenamiento de tiempo ilimitado, con los menores componentes posibles y ligera transportación. La invención consiste en la construcción de una pila utilizando electrodos de carbón poroso y de magnesio y, como electrolito, la savia de los árboles. Los elementos, formas y disposición de la pila están concebidos para asegurar la solidez y rendimiento eléctrico de la misma.
Patent MA-20170-A1 (MA)
Inventor: LOUIS DEGUERRY
IPC: B66F11/04
Filed: 1984-07-10
Abstract: An elevator has a horizontal chassis, a telescopingly extensible and retractable mast having upper and lower ends, a guide extending along the mast between its ends, and a platform adapted to support a worker and displaceable in the guide along the mast between its ends. The lower end of the mast is pivoted on the chassis for movement of the mast relative to the chassis between an erect position with the upper end above the lower end and a recumbent position with the mast lying on the chassis and the mast ends generally level with each other. This axis is sufficiently above the chassis that in the recumbent position the platform can lie between the chassis and the mast. The chassis has opposite ends, one of which carries the mast and pivot. The center of mass of the mass is horizontally between the pivot axis and the other chassis end so that a drive connected between the chassis and the mast first pivots the mast about the axis from the recumbent to the erect position and then vertically extends the mast and raises the platform. This drive is normally a motor mounted on the chassis and having a drum and a cable connected between the drum and the mast.
Patent MA-20888-A1 (MA)
Inventor: RONALD EDWARD STEELE
IPC: A61K31/14
Filed: 1987-03-05
Abstract: Heterocyclylalkylbenzonitrile derivs. of formula (I) and their salts are new (where R, R' = H or 1-7C alkyl; or R+R' when on adjacent C atoms, together with the benzene ring form a naphthalene or tetrahydronaphthalene ring system; R1 = H; R2 = H, 1-7C alkyl, 2-7C alkenyl, aryl, aryl-(1-7C)alkyl, 3-6C cycloalkyl or (3-6C)cycloalkyl-(1-7C)alkyl; or R1+R2 = 1-7C alkylidene opt. substd. by mono- or di-aryl, or 4-6C n-alkylene, n-alkylene substd. by 1-7C alkyl or 2-4C n-alkylene bridged by o-phenylene, to form with the attached C a corresp. opt. substd. or benzo-fused 5-, 6- or 7-membered ring; W = 1-imidazolyl, 1,2,4- or 1,3,4-triazol-1-yl or 3-pyridyl each opt. substd. by 1-7C alkyl). 1-Cyano-4-imidazolylnaphthalenes of formula (II) and their salts are new (where R1' = H; R2' = H, 1-7C alkyl, Ph, 1-7C alkylthio, Ph-(1-7C)alkylthio, PhS, pyridyl, thienyl or benzyl, or Ph, Ph-(1-7C)alkylthio, PhS or benzyl each ring mono-substd. by CN, 1-7C alkyl, 1-7C alkoxy, OH, 1-7C alkanoyloxy, aroyloxy, NO2, halogen, CF3, 1-7C alkanoyl, aroyl, 1-7C alkylsulphonyl, or CONH2 or SO2NH2 both opt. substd. by 1 or 2 1-7C alkyls; or R1'+R2' = 1-7C alkylidene, benzylidene, diphenylmethylidene or 4-6C n-alkylene; R3 = H or 1-7C alkyl).
Patent MA-26557-A1 (MA)
Inventor: GARETH HAYDN WILLIAMS
IPC: C12P/
Filed: 1998-10-21
Abstract: Methods tor determining cell growth abnormalities, particularly cancerous or pre-cancerous cells, are described in which polypeptides involved in the preinitiation complex of DNA replication are detected. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Typically antibodies detecting these proteins are used in screening assays on tissue sections or smears. The detection of RNA encoding these proteins is also described. The application is particularly concerned with cervical neoplasia's but also describes screening for growth abnormalities of breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract tissue.
Patent MA-25176-A1 (MA)
Title: Instrument pour mesurer la longueur d'une trajectoire
Inventor: MOUKHTARI ABDELOUAHED
IPC: G01B21/00
Filed: 2000-09-21
Abstract: L'INVENTION CONCERNE UN INSTRUMENT POUR MESURER LA LONGUEUR D'UNE TRAJECTOIRE QUEL SOIT SA FORME :  DROITE,  COURBÉE OU AUTRES ,  AVEC UNE GRANDE PRÉ