baber/WOPTO huggingface dataset:
Patent EA-009176-B1 (EA)
Title: Processes for preparation of 7 alpha-carboxyl 9,11-epoxy steroids and intermediates useful therein and a general process for the epoxidation of olefinic double bonds
Inventor: NG JOHN S
IPC: A61K31/58
Filed: 1996-12-11
Abstract: Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of formula (I),wherein: -A-A- represents the group –CHR-CHR- or –CR=CR-;R, Rand Rare independently selected from the group consisting of hydrogen, halo, hydroxy, C-Calkyl, C-Calkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy; Rrepresents an alpha-oriented lower alkoxycarbonyl or hydroxyalkyl radical; -B-B- represents the group –CHR-CHR- or an alpha- or beta- oriented group of formula (III),where Rand Rare independently selected from the group consisting of hydrogen, halo, C-Calkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, and Rand Rare independently selected from the group consisting of hydrogen, halo, C-Calkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, or Rand Rtogether comprise a carbocyclic or heterocyclic ring structure, or Ror Rtogether with Ror Rcomprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring, unless stated otherwise, alkyl or a substituent alkyl moiety may contain from 1 to 6 carbon atoms.
Patent EA-006702-B1 (EA)
Title: Method for determining the sequence of a polynucleotide
Inventor: DENSHAM DANIEL HENRY
IPC: C12Q1/6869
Filed: 2000-10-06
Abstract: A method for determining the sequence of a polynucleotide, comprising the steps of: i. reacting a target polynucleotide with at least an enzyme that is capable of interacting with and precessing along the polynucleotide, under conditions sufficient to induce enzyme activity; and ii. detecting conformational changes in the enzyme as the enzyme processes along the polynucleotide; for carrying out the method a solid support is used comprising at least one immobilised enzyme capable of interacting with the target polynucleotide and precessing along it the polynucleotide, the enzyme being labelled with one or more detectable labels; and a system for determining the sequence of the polynucleotide comprising such solid support and an apparatus for detecting the label.
Patent EA-006116-B1 (EA)
Title: Rotary machine and thermal cycle
Inventor: DUNCAN RONNIE J
IPC: F01C1/10
Filed: 2002-05-07
Abstract: A rotary machine having a housing with rotary components disclosed within. The rotary machine is configurable as an internal combustion rotary engine, an external combustion rotary engine, a gas compressor, a vacuum pump, a liquid pump, a drive turbine, or a drive turbine for expandable gases or pressurized liquids. The combustion engine employs a new thermal cycle-eliminating the Otto cycle's internal compression of the combustion products as part of the cycle. The new combustion thermal cycle is intake, expansion and exhaust.
Patent EA-006499-B1 (EA)
Title: Railroad freight car truck suspension yaw stabilization device
Inventor: BULLOCK ROBERT LEE
IPC: B61F5/06
Filed: 2004-04-27
Abstract: Yaw stabilization device (51, 52) for a railroad car truck provides a light-weight mechanism for increasing the linear yaw stiffness levels between the side frame (22, 24) and bolster (38) to provide the proper inter-axle shear stiffness without affecting the compliancy required of the vertical suspension system. This invention, which fails to increase the unsprung weight of a railroad car truck assembly (20) noticeably, may be retrofitted to existing freight car trucks in service or incorporated into newly manufactured trucks. Moreover, it does so without the need for damping wedges to increase interaxle shear stiffness and allow the wedges to function optimally for control of vertical vibrations.
Patent EA-012583-B1 (EA)
Title: Aerosol formulation for inhalation of beta agonists
Inventor: AVEN MICHAEL
IPC: A61K31/536
Filed: 2005-05-10
Abstract: The invention relates to a propellant-free aerosol formulation for inhalation, which comprises one or more compounds of general formula (1),wherein the groups R, R, Rand Xare defined as in the claims and in the description.
Patent EA-011921-B1 (EA)
Title: Rotor sliding-vane machine
Inventor: STROGANOV ALEXANDER ANATOLYEVI
IPC: F04C2/344
Filed: 2006-03-31
Abstract: The invention relates to mechanical engineering and can be used as rotary gate high-pressure machine with uniform volumetric feed which can operate as a pump or as a hydraulic motor. The invention is aimed at overcoming reasons causing increased power dissipative loss, as well as at reliability increase by creating means of hydrostatic rotor balancing adjustment and mobile packing, resistant to the machine elements wear and working fluid contamination, and also compatible with means of cavitation overcoming in vane chambers. A rotor sliding-vane machine comprises a rotor including working (1) and supporting parts (4) connected via force chambers (6) of variable length so that they rotate synchronously with a possibility of little reciprocal axial movements and tilts. The vanes (8) are located in vane chambers (7) of the working part (1) of the rotor and when the rotor is rotating they cyclically change the degree of protrusion into the annular groove (2) made on the face surface of the working part of the rotor. Between the supporting cover plate (5) of the housing and supporting part of the rotor there are supporting cavities hydraulically connected via the means of local pressures balancing to the force chambers of variable length and cavities of the working chamber in the annular groove of the working part of the rotor. Supporting cavities and force chambers of variable length are made so that pressure forces of the working fluid contained in the force chambers significantly balance pressure forces of the working fluid forcing out the working and supporting parts of the rotor from the working and supporting cover plates of the housing providing just a small tightening required for insulation. Losses for friction and cavitation are reduced and reliability of rotary gate machines is improved.
Patent EA-013483-B1 (EA)
Title: A gasket and a washing machine having the same
Inventor: GRACIA BOBED ISMAEL
IPC: D06F37/26
Filed: 2006-11-29
Abstract: An improved gasket (1) for a drum-type washing machine comprises a front flange (11) and a rear flange (15). Between the front flange (11) and the rear flange (15), a first substantially U-shaped section (13) connects to the front flange (11) and a second section (14) connects said first section (13) and the rear flange (15), wherein said second section (14) has a substantially flat contour at a lower position and increasingly curves outwardly from the axis from the lower position to a lateral position while decreasingly curves outwardly from the axis from the lateral position to an upper position opposite to said lower position. In such a configuration, said gasket (1) can absorb the greater vibration occurred in the lateral position in a normal washing operation process.
Patent EA-015173-B1 (EA)
Title: Combination therapy using anti-egfr and anti-her2 antibodies
Inventor: GILLIES STEPHEN D
IPC: A61K39/395
Filed: 2006-12-15
Abstract: The invention relates to the combined use of anti-EGFR antibodies and anti-Her2 antibodies for the treatment of cancer, especially suitable for cancer expressing high levels of the EGFR type and low levels of HER2. The invention refers in particular monoclonal antibody "trastuzumab" (HERCEPTIN®)) directed against the HER2 receptors the efficacy of which can be significantly increased in vivo when combined with monoclonal antibody "matuzumab" (hmAB 425, EMD 72000) directed against EGF receptors. The combination treatment is suitable for patients suffering from cancer having said receptor profile, preferably pancreatic cancer.
Patent EA-014282-B1 (EA)
Title: Method for geophysical prospecting
Inventor: SCHONEWILLE MICHEL ALBERT
IPC: G01V1/36
Filed: 2009-03-11
Abstract: An estimated frequency-wavenumber spectrum is generated by applying a first Anti-leakage Fourier transform method to aliased frequency components in temporal-transformed seismic data and applying a second Anti-leakage Fourier transform method to unaliased frequency components in the temporal-transformed seismic data. The second Anti-leakage Fourier transform method applies an absolute frequency-wavenumber spectrum extrapolated from unaliased frequencies to aliased frequencies to weight frequency-wavenumber components of the aliased frequencies. An inverse temporal and spatial Fourier transform is applied to the estimated frequency-wavenumber spectrum, generating trace interpolation of the seismic data.
Patent EA-013395-B1 (EA)
Title: Optical protective element, method for making thereof and a method of verification object authen ticity using said protective element
Inventor: KARASEV ANDREY LVOVICH
IPC: B42D15/10
Filed: 2009-06-25
Abstract: The invention relates to a protective element usable as a transparent window in an object to be protected, a method to making thereof and a method of verification object's authenticity with said protective element. According to the method of making a protective element there provided a substrate (1) transparent in visible and ultra-violet spectral region, a latent image (2) is imprinted at least one portion of the substrate (1) on of the sides thereof using a colorless liquid composition comprising UV absorber with red spectrum edge absorption within 370-400 nanometer; a latent image (2') is imprinted on the other side of the substrate (1) using a colorless liquid composition comprising UV absorber with red spectrum edge absorption within 270-360 nanometer, so that latent images (2) and (2') on both sides of the substrate (1) are arranged independently of each other and/or arranged in the predetermined agreed position relative each other enabling to provide a complex image at visualization thereof, subject the obtained latent image (2), (2') to curing at 70-80°C, a protective thin layer (3) transparent in UV spectrum region is applied on both sides of the substrate (1) through the entire surface thereof, wherein the reflective power of the protective layer (3) substantially coincides with the reflective power of the substrate (1) material and the latent images (2), (2') providing invisibility of the latent images outline forming with the naked eye, build in the obtained substrate (1) as a transparent window in an object to be protected. In the method of verification object's authenticity with said protective element the object with protective optic element is placed between a UV light source and a screen fluorescent under the UV light and in irradiation the protective element by light with the predetermined wave length there provided visualization of portions with latent image as dark image (5) at a luminous screen (4).
Patent EA-018278-B1 (EA)
Title: Polyolefin composition comrising polyethylene, cable and wire produced therefrom, use thereof, silanol condensation catalyst, pigment based on titanium dioxide and use thereof
Inventor: CARLSSON ROGER
IPC: C08J3/24
Filed: 2008-12-11
Abstract: The present invention relates to a poleolefin composition comprising a crosslinkable polyolefin with hydrolysable silane groups, a Bronstedt acid silanol condensation catalyst and a pigment based on titanium dioxide where in case if the pigment does not comprise a coating containing silicon and the concentration of the titanium dioxide in said pigment containing composition is at least 93 wt% or in case if the titanium dioxide in said pigment containing composition is coated, which coating contains silicon, and the concentration of the titanium dioxide in said titanium dioxide containing composition is at least 97 wt%, characterized in that the difference between the highest torque value, when the crosslinking is completed, and the lowest torque value, before the crosslinking starts, both values measured at 120°C, is 40 Nm or higher. Besides, the invention relates to the production of cable and wire, use said composition therefor and use said pigment based on titanium dioxide.
Patent EA-017239-B1 (EA)
Title: Medical compress i
Inventor: HOFSTETTER JUERGEN
IPC: A61F13/00
Filed: 2008-07-12
Abstract: The invention relates to medical compresses, especially gauze compresses, that can be especially advantageously folded. The invention also relates to a stack comprising a plurality of compresses, and a method for producing said compresses.
Patent EA-020921-B1 (EA)
Title: Cyclohexyl amide derivatives and their use as crf-1 receptor antagonists
Inventor: BEATTIE DAVID
IPC: C07D277/42
Filed: 2009-08-05
Abstract: The present invention relates to cyclohexyl amide derivatives of formula (XI) useful as corticotropin releasing factor (CRF-11) receptor antagonists.
Patent EA-020450-B1 (EA)
Title: Emergency power supply apparatus
Inventor: MOTH KLAUS
IPC: H02J9/06
Filed: 2009-10-01
Abstract: A modular emergency power system architecture (200) with a plurality of output power supply lines for feeding power to a destination, in which the operational status of each output power supply line is configurable. The architecture comprises a plurality of load bars (208, 209) from which power is delivered to the destination. The load bars (208, 209) are selectively connectable to send power to or receive AC power from a mains supply (202) and/or a DC bus (210) via one or more AC/DC power conversion modules (212, 214). The DC bus (210) is connected to receive a secondary (e.g. emergency) power supply (218, 224). The architecture may provide redundancy and on-the-fly reconfigurability to complement changes in the physical location of critical components in the destination, e.g. caused by virtualisation, zoning or repair. The architecture is operable as a stand-alone uninterruptible power supply (UPS) or as an extended runtime generator for an existing UPS.
Patent EA-031107-B1 (EA)
Title: Method for separating liquid from suspended matter in a sludge and device for same
Inventor: CAPEAU PATRICE
IPC: C02F11/14
Filed: 2011-10-28
Abstract: The invention relates to a method for separating the liquid part from the suspended matter in a sludge supplied in a continuous flow at a flow rate of Q=V/hour. The flow is divided into at least two partial flows which are sprayed on top of one another into a sealed chamber of volume v<V/20, simultaneously injecting air therein at a flow rate d, said chamber being kept under overpressure conditions. The suspended matter of the thus treated flow is then left to decant in a collection container, with the cake or solid part falling to the bottom and separating from the liquid part which is continuously discharged.
Patent EA-025810-B1 (EA)
Title: Downhole packer and method for completing a wellbore in a subsurface formation
Inventor: YEH CHARLES S
IPC: E21B33/12
Filed: 2011-11-17
Abstract: The present invention relates to the field of well completions and, more specifically, to the isolation of formations in connection with wellbores that have been completed using gravel-packing. An apparatus and method for completing a wellbore including providing a packer having an inner mandrel, alternate flow channels along the inner mandrel, and a sealing element external to the inner mandrel, including connecting packer to tubular body, then running the packer and connected tubular body into the wellbore. In one aspect, the packer and connected tubular body may be placed along an open-hole portion of the wellbore. Tubular body may be a sand screen, with the sand screen comprising a base pipe, a surrounding filter medium, and alternate flow channels. The method includes setting a packer and injecting a gravel slurry into an annular region formed between the tubular body and the surrounding wellbore, and then further injecting the gravel slurry through the alternate flow channels to allow the gravel slurry to at least partially bypass sealing element of the packer.
Patent EA-025898-B1 (EA)
Title: Solar plant for hot water supply
Inventor: SALAMOV OKTAJ MUSTAFA OGLY
IPC: F24S90/00
Filed: 2014-02-12
Abstract: The invention is related to the field of solar technology and heat power engineering, in particular, to hot water supply devices using flat sunlight collectors. The objective of the invention is simpler design of the plant, higher efficiency of solar energy utilization, automation of heat-exchange processes and discharge of spent water to a sewerage system, and better ecological indicators of the system. For attaining the above-stated objective, a solar plant is provided comprising flat sunlight collectors (FSC), a hot water tank (HWT), a spent hot water tank (SHWT) provided with heat insulation, a heat pump (HP), a circulation pump and a heat exchanger, the SHWT is installed in a separate room or in soil at a level higher than that of the sewerage line (SL), provided with heat insulation and has one inlet for spent water and two outlets, one of which, located in the upper portion of the side wall, communicates with SL directly while the other inlet located in the SHWT bottom communicates with SL through a controlled valve (CV). The heat exchanger mounted inside HWT is connected, through the circulation pump, to the FSC circulation line; also mounted inside HWT is HP condenser, while HP evaporator is mounted inside SHWT. Further, SHWT and HWT are provided with temperature-sensitive elements connected, respectively, to the first and the second temperature relays (TR), the latter being differentially connected to inputs of an automatic control unit (ACU) powered by a low-power current source. ACU outputs are connected to CV and to HP compressor, respectively. The SHWT inlet is located in the lower portion of its side wall, at a level of 1/5 height, and the HP evaporator is mounted horizontally in the lower part of SHWT. The first TR has one normally open and one normally closed contact that change their position at a temperature of spent hot water lower than 10°C, and the second TR has one normally closed contact that changes its position at a hot water temperature higher than 80°C. The normally closed contact of the first TR is included in the CV powering circuit, while its normally open contact is connected in series with the normally closed contact of the second TR and included in the circuit powering the HP compressor. The proposed invention is of great practical significance. As an independent plant, it can be used for non-interruptible hot water supply to a number of facilities, in particular, public bath houses and laundries. The plant is simple in design and environmentally safe. Recuperation of heat from spent hot water allows 60-70% saving of initial FSC energy.
Patent EA-025161-B1 (EA)
Title: Antimicrobial composition
Inventor: CORNMELL ROBERT JOSEPH
IPC: A61K31/05
Filed: 2012-12-05
Abstract: The present invention relates to an antimicrobial composition and a method for disinfection involving the antimicrobial composition. It particularly relates to an antimicrobial composition for personal cleaning, oral care or hard surface cleaning applications. It was found that compositions comprising one or more monosubstituted phenols, terpineol and a carrier provide synergistic antimicrobial action. In a preferred aspect the composition also comprises 1 to 80 wt.% of one or more surfactants.
Patent EA-025999-B1 (EA)
Title: Polymeric yarn and garments comprising same
Inventor: VERDAASDONK PETO
IPC: D02G3/02
Filed: 2013-04-02
Abstract: The invention relates to a yarn comprising polymeric filaments and/or polymeric staple fibers containing a filler, wherein said filler is a plurality of fibrils having an average length of not more than 200 μm.
Patent EA-029907-B1 (EA)
Title: Modified oligonucleotides comprising thiol functions and the use of same for the detection of nucleic acids
Inventor: FOURNIER-WIRTH CHANTAL
IPC: G01N33/50
Filed: 2013-04-04
Abstract: The present invention relates to modified oligonucleotides corresponding to formulas below, having two or more thiol functions, capable of being immobilised on a gold surface or on a grafted surface, in particular a surface comprising at least one carbon-carbon double bond or one carbon-carbon triple bond or halogen acetamide functions, preferably maleimide or acrylamide functions. The invention further relates to a method for detecting a nucleic acid in a biological sample comprising a step of detecting hybridisation between a modified oligonucleotide and an amplified target nucleic acid from the biological sample. The invention also relates to a kit and the use for detecting, genotyping or sequencing of a pathogenic organism, preferably a virus.
Patent EA-027547-B1 (EA)
Title: Anhydrous, amorphous and porous magnesium carbonates and methods of production thereof
Inventor: STROEMME MARIA
IPC: C01B32/60
Filed: 2013-12-04
Abstract: An X-ray amorphous magnesium carbonate is disclosed that is characterized by a cumulative pore volume of pores with a diameter smaller than 10 nm of at least 0.018 cm/g, and a specific surface areas of at least 60 m/g. The X-ray amorphous magnesium carbonate is produced by reacting an inorganic magnesium compound with alcohol in a COatmosphere. The X-ray amorphous magnesium carbonate can be a powder or a pellet and acts as a desiccant in, for example, production of food, chemicals or pharmaceuticals.
Patent EA-034134-B1 (EA)
Title: Element for amusement articles, corresponding system and method
Inventor: GRUENEWALD UWE
IPC: A63H33/08
Filed: 2014-04-18
Abstract: An element (10) of amusement articles includes a flat body with two opposite faces (10a, 10b), a hub region (12), and a contour region (14) around the hub region (12), a plurality of coupling elements arranged facing one another along the contour region (14) in an alternating sequence of first coupling elements (18) and second coupling elements (16, 28), wherein the first coupling elements are in the form of swivel- coupling recesses (18) and the second coupling elements are chosen from between: a) toothed coupling sectors (16); and b) swivel-engagement heads (28) complementary to said swivel-coupling recesses (18), and complementary axial-engagement formations (20a, 20b) provided on one (10a) and the other (10b) of said opposite faces. The element (10) may be used as pendant or necklace, as component of a modular construction toy, possibly with different possibilities of connection, such as (e.g., radial and axial) coupling and swivel connection, as wheel (e.g., for providing models of wheeled vehicles), and/or for creating toys, such as statuettes or "characters" with added parts, which may be articulated. The element (10) may be used for creating, for example, surprises to be put in chocolate eggs and the like.
Patent EA-030321-B1 (EA)
Title: Method and plant for producing iron from roasted pyrites
Inventor: BOEHRINGER BERTRAM
IPC: C22B11/08
Filed: 2013-06-24
Abstract: The present invention provides a method and a recovery system for obtaining/recovering metallic iron and/or iron compounds, in particular iron chloride, from ores and/or ore tailings, especially from pyrite tailings, preferably from roasted pyrites produced during sulphuric acid manufacture.
Patent EA-036591-B1 (EA)
Title: Method for inhibiting, delaying or reducing tumor growth in a subject with cancer
Inventor: EVANS ELIZABETH E
IPC: C12N5/07
Filed: 2014-06-20
Abstract: The invention relates to a method for inhibiting, delaying or reducing tumor growth in a subject with cancer, comprising administering to the subject an effective amount of an isolated antibody or antigen-binding fragment thereof which specifically binds to semaphorin-4D (SEMA4D) and an effective amount of at least one other immune modulating agent selected from adoptive T lymphocytes, an immune checkpoint blockade inhibitor and a regulatory T lymphocyte (Treg) modulator. The method by the invention provides enhanced therapeutic efficacy relative to the use of one of said agents alone.