baber/WOPTO huggingface dataset:
Patent CO-6210734-A2 (CO)
Title: Conjugados de anticuerpo anti-rg-1
Inventor: KING DAVID J
IPC: A61K47/48
Filed: 2010-05-28
Abstract: Se describen anticuerpos anti-RG-1, fragmentos de anticuerpo o miméticos de anticuerpo conjugados a moléculas asociadas, tales como fármacos, radioisótopos y citotoxinas, en donde la molécula asociada ejerce su efecto independientemente de si el conjugado unido a RG-1 es internalizado dentro de una célula seleccionada, los cuales son útiles para tratar cánceres. 1.- Un conjugado anticuerpo-molécula asociada caracterizado porque comprende un anticuerpo monoclonal humano o una porción de unión a antígeno del mismo conjugado a una molécula asociada, en donde el anticuerpo o porción de unión a antígeno del mismo se une a RC-1 humano y conjugado exhibe por lo menos una de las siguientes propiedades: se une a RG-1 con una KD de 1 x 10-8 M o menos; inhibe el crecimiento de células que expresan RG-1 in vivo. 2.- El conjugado de conformidad con la reivindicación 1, caracterizado porque el anticuerpo o porción de unión a antígeno del mismo comprende: (a) una CDR1 de la región variable de la cadena pesada que comprende SEQ ID NO: 1; (b) una CDR2 de la región variable de la cadena pesada que comprende SEQ ID NO: 3; (c) una CDR3 de la región variable de la cadena pesada que comprende SEQ ID NO: 5; (d) una CDR1 de la región variable de la cadena ligera que comprende SEQ ID NO: 7; (e) una CDR2 de la región variable de la cadena ligera que comprende SEQ ID NO; 9; y (f) una CDR3 de la región variable de la cadena ligera que comprende SEQ ID NO: 11. 3.- El conjugado de conformidad con la reivindicación 1, caracterizado porque el anticuerpo o porción de unión a antígeno del mismo comprende: (a) una CDR1 de la región variable de la cadena pesada que comprende SEQ ID NO: 2; (b) una CDR2 de la región variable de la cadena pesada que comprende SEQ ID NO: 4; (c) una CDR3 de la región variable de la cadena pesada que comprende SEQ ID NO: 6; (d) una CDR1 de la región variable de la cadena ligera que comprende SEQ ID NO: 8; (e) una CDR2 de la región variable de la cadena ligera que comprende SEQ ID NO: 10; y (f) una CDR3 de la región variable de la cadena ligera que comprende SEQ ID NO: 12.
Patent CO-6341619-A2 (CO)
Title: Metodos para preparar compuestos biciclicos basados en imidazol
Inventor: CHEN JASON GUOHUA
IPC: A61K31/42
Filed: 2011-01-18
Abstract: Métodos para preparar los compuestos de la fórmula I, en donde: A es un heterociclo opcionalmente sustituido; R1 es N(R1A)2, hidrógeno, hidroxi, o alquilo opcionalmente sustituido, arilo, alquilarilo, arilalquilo, heteroalquilo, heterociclo, alquilheterociclo, o heterocicloalquilo; y cada R1A es independientemente hidrógeno o alquilo opcionalmente sustituido, arilo, alquilarilo, arilalquilo, heteroalquilo, heterociclo, alquilheterociclo, o heterocicloalquilo.
Patent CO-6491051-A2 (CO)
Title: Sistema y proceso integrados para la producción de bioproductos
Inventor: WALTHER DAVID C
IPC: C12M1/00
Filed: 2012-01-18
Abstract: Se proporcionan procesos y sistemas para la producci6n de bioproductos tales como biocombustibles. Los procesos y sistemas de producción de bioproductos utilizan el pre-tratamiento de una materia prima que contiene carbohidrato para producir moléculas de azúcar solubles y la conversión continua de la materia prima pre-tratada a un bioproducto mediante un microorganismo de fermentación inmovilizado.
Patent CO-6670530-A2 (CO)
Title: Tapa para una olla exprés
Inventor: SCHULTZ HORST
IPC: A47J45/07
Filed: 2013-01-04
Abstract: La invención se refiere a una tapa para una olla exprés, en la que un módulo de tapa superior, compuesto por una unidad de cierre con un botón y una placa central, está fijado de modo que se puede retirar en una carcasa de la válvula dispuesta de modo central de una tapa ranurada con la obturación de un módulo de tapa inferior, y se puede retirar conjuntamente con un mecanismo de enclavamiento del módulo de tapa inferior.
Patent CO-7111294-A2 (CO)
Title: Anticuerpo anti-fgfr2
Inventor: OHTSUKA TOSHIAKI
IPC: G01N33/574
Filed: 2014-10-23
Abstract: La presente invención proporciona un anticuerpo que se une a un receptor de factor de crecimiento de fibroblastos.
Patent EP-1032156-A2 (EP)
Inventor: CASO GREGORY S
IPC: H03H17/00
Filed: 2000-02-24
Abstract: The invention is a digital channelizer (100) and
process which divides an input bandwidth into at least some
of N channels. The digital channelizer includes an analog
to digital converter (14) which encodes the input bandwidth
into a serial digital data stream of data words;
a demultiplexer (16), coupled to the analog to digital
converter, which divides the serial digital data stream into
the parallel data streams of data words; a window
presum (102) having N outputs, coupled to the parallel data
streams, each output being a function of a window presum
function and data words from a plurality of the parallel
data streams; and a discrete Fourier transform
apparatus (26'), having N inputs coupled to the N outputs of
the window presum, which performs a discrete Fourier
transform on N inputs to produce an output of at least some
of the N channels.
Patent EP-1018612-A2 (EP)
Inventor: KATAUMI YOSHIMASA
IPC: F16H59/02
Filed: 1996-10-24
Abstract: A shift lever device for an automotive automatic transmission comprising a base
bracket (11) fixed on a vehicle floor, said base bracket having an automatic mode shift slot,
a manual mode shift slot parallel to the automatic mode shift slot and a switching slot (23c)
connecting the automatic mode shift slot and the manual mode shift slot, a shift lever (15,18)
supported to said base bracket so as to be swingable in the fore-and-aft direction of
an automotive vehicle, said shift lever being extended over said base bracket so as to
be moved through the automatic mode shift slot, the manual mode shift slot and the
switching slot, and a selector lever (16) interconnected with an automatic transmission
through a linkage so as to change a shift position in an automatic shift mode. Said
selector lever being integrally swung with said shift lever when said shift lever is put in
the automatic mode shift slot, said selector lever being released from said shift lever
when said shift lever is put in the manual mode shift slot to electrically execute an up-shift
and down-shift through a fore-and-aft direction swing of said shift lever. A lower
end portion of the shift lever and a lower end portion of the selector lever are
supported to a shaft portion (13) so that the shift lever and said selector lever are
swingable in the fore-and-aft direction of the automotive vehicle.
Patent EP-1074975-A2 (EP)
Inventor: OKUNO DAISUKE
IPC: H03M13/03
Filed: 2000-07-27
Abstract: A audio decoding device includes an error correction
processing means 13 for generating interpolation process
information, a soft decision information generating means 12a for
generating a soft decision information indicating a current
situation of the transmission line based on coded data, a audio
decoding processing means 14 for applying an interpolation
process to the audio code in unit of bit based on interpolation
information and soft decision information and then decoding the
audio code which is subjected to the interpolation process to
generate audio data, and a audio output processing means 15 for
outputting the audio data.
Patent EP-1077456-A2 (EP)
Inventor: KONDA KAZUMOTO
IPC: H01H9/08
Filed: 2000-08-18
Abstract: In the breaker device, a pair of stationary electrodes
20, 21 are arranged on the front and the rear side of the
protruding wall 18, that is, the pair of stationary
electrodes 20, 21 are collected at one place. Therefore,
the pair of stationary electrodes 20, 21 have a space round
both the stationary electrodes in common. Accordingly, the
size of the breaker device can be reduced. Further, when
the radius of curvature of the continuity section 73
connecting the pinching pieces 71, 72 is made large,
concentration of stress in the movable electrode 70 can be
relieved. Therefore, the pinching forces of both the
pinching pieces 71, 72 can be increased. Accordingly, it
is possible to ensure a sufficiently high contact pressure
between the movable electrode 70 and the stationary
electrodes 20, 21.
Patent EP-1100194-A2 (EP)
Inventor: YOSHIMOTO SUSUMU
IPC: H03H9/02
Filed: 2000-11-09
Abstract: The present invention disclosed a SAW filter in which unnecessary space on a chip
(11) can be reduced in comparison with the prior art, and in which a smaller chip can be
realized. Because oblique step shaped reflection surfaces (14, 15, 54, 55, 64, 65) are
provided in- order to reflect the SAW, a smaller SAW filter than that used in the prior art
can be realized (Figure 1).
Patent EP-1129794-A2 (EP)
Inventor: RUNG JUERGEN
IPC: B08B9/34
Filed: 2000-12-13
Abstract: The nozzles (9) of the device for CIP cleaning are movable from a work position across or perpendicular to the movement of the support (1) into a cleaning position whereby the spray nozzles of two adjoining nozzle assemblies (11) can each be connected together through a CIP connecting element. The nozzle assemblies can be spread out on a support rotating about a vertical machine axis (VA) so that the spray nozzles move in and out relative to the machine axis between the work and cleaning positions.
Patent EP-1114891-A2 (EP)
Title: Calender
Inventor: MUELLER HORST
IPC: D21G1/00
Filed: 2000-12-19
Abstract: A calender with rollers, comprises a roller stack assembled on the lower side of an inclined stand (1). The roller transport carriage (15) travels longitudinally below it. A hoist (13) brings rollers individually from the carriage for installation into the appropriate positions. It lowers them back to the carriage when dismounting them.
Patent EP-1044987-A2 (EP)
Title: Gapped 2'-modified oligonucleotides
Inventor: MONIA BRETT P
IPC: C12Q1/68
Filed: 1992-12-23
Abstract: Oligonucleotides and other macromolecules are provided
that have increased nuclease resistance, substituent
groups for increasing binding affinity to complementary
strand, and subsequences of 2'-deoxy- erythropentofuranosyl
nucleotides that activate RNase H enzyme.
Such oligonucleotides and macromolecules are useful for
diagnostics and other research purposes, for modulating
protein in organisms, and for the diagnosis, detection
and treatment of other conditions susceptible to
antisense therapeutics.
Patent EP-1063101-A2 (EP)
Inventor: INOUE YASUTOSHI
IPC: B41M3/00
Filed: 2000-06-22
Abstract: There are provided printed matter whose image surface
has uniform gloss and whose image formed of ink is of high
quality, has enhanced appearance, does not have its left and
right sides reversed, and is easy to see; a printing method
which allows the printed matter to be easily obtained, and a
printer which makes it possible to easily realize the
printing method. The image which is a mirror image formed
with ink is formed within an image-formation area of a
surface of a print medium which is a transparent member.
Then, a surface of the image and at least a blank space
section within the image-formation area of the print medium
are covered with an underlying layer (8) formed with
underlying layer ink, after which a surface of the
underlying layer is covered with a light-shielding layer
formed with light-shielding layer ink.
Patent EP-1109421-A2 (EP)
Inventor: ALLRED RUSTIN W
IPC: H04B3/06
Filed: 2000-12-07
Abstract: A self-adaptive graphic equalizer 30 operable to
equalize the effects of an audio system on an audio
signal includes an adaptive graphic equalizer 34 having a
plurality of equalizing filters 38, 40, where the
plurality of equalizing filters have different center
frequencies equidistant from one another and spanning a
predetermined audio bandwidth. Each equalizing filter 38,
40 is operable to filter an i th  sub-band of the audio
signal. A plurality of first filters are coupled to the
audio system, each first filter is operable to filter an
i th  sub-band of an output signal of the audio system. A
plurality of second filters are operable to filter an i th 
sub-band of the audio signal. A gain adjuster 42 is
operable to adjust the i th  sub-band of the adaptive
graphic equalizer in response to a difference in the i th 
sub-band of the filtered output signal from the plurality
of first filters and the i th  sub-band of the filtered
audio signal from the plurality of second filters.
Patent EP-1113324-A2 (EP)
Inventor: SLUSAREK WOJCIECH K
IPC: G03C7/413
Filed: 2000-12-15
Abstract: This invention relates to an imaging element, such as a
photographic or photothermographic element comprising a silver halide emulsion
layer, wherein the element also comprises a compound of Structure I:
 
wherein the substituents are as defined in the specification.
Patent EP-1109140-A2 (EP)
Inventor: HAUSER HUBERT
IPC: C03C27/12
Filed: 2000-12-05
Abstract: Glass pane unit clamped pane (2) with electrical conductor structure(10) on its surface and electrical connecting wires are led to edge of pane(2). The protective layer (15) is a non-conductive plastics film which, after the wires have fused, is against the glass pane (2) in a force fit or material bond with the connections (11). The glass pane unit (1), for an alarm box, has at least one clamped pane (2) with an electrical conductor structure (10) on its surface and the electrical connecting wires are led to the edge of the pane (2). One connecting wire is insulated against the other and has a non-conductive thin protective layer on the side away from the glass pane (2). The protective layer (15) is a non-conductive plastics film which, after the wires have fused, is against the glass pane (2) in a force fit or material bond with the connections (11).
Patent EP-1175790-A2 (EP)
Inventor: GARCIA-MARTIN MIGUEL-ANGEL
IPC: H04Q3/00
Filed: 2000-04-17
Abstract: A method of routing signalling information at a signalling point of a telecommunications network. A Global Title Routing Case (GTRC) table is provided for mapping Global Titles to GTRCs, where each GTRC is allocated a primary and secondary destination signalling point. At least one peak time period is predefined, and said primary and secondary destination signalling points are swapped for a fraction of said GTRCs during said peak period to allow for load sharing during this period. For a signalling transfer request received at the signalling point, the Global Title associated with the request is mapped to a GTRC using the GTRC table, and the destination signalling point is determined in dependence upon the primary and secondary destination signalling points allocated to the mapped GTRC and signalling point availability, and, in the case of said fraction of GTRCs, the time at which the request is received.
Patent EP-1181145-A2 (EP)
Title: Procede d'ajustement de la transmission de la vapeur d'eau et d'autres proprietes dans un film a base de polyolefine
Inventor: BRADY KEVIN A
IPC: C08K3/00
Filed: 2000-05-15
Abstract: L'invention concerne un procédé qui permet de rendre moins résistants au passage de la vapeur d'eau des films, des composites en film et des articles réalisés avec ce type de matériau, en faisant passer dans le pincement de rouleaux rainurés d'interdigitation un film ou composite en film précurseur rempli. En règle générale, les films ou composites en film sont à base de polyoléfine ou de mélange de polyoléfines induisant la formation de film précurseur ou de film, avec une charge de remplissage relativement élevée et éventuellement un élastomère. L'invention concerne un procédé de fabrication de couches de bébé ou autres articles jetables par lequel une résistance relativement élevée au passage de la vapeur d'eau est combinée à une résistance au passage de liquide. Selon une variante, les rouleaux rainurés d'interdigitation sont maintenus dans une gamme de températures allant d'environ 91 °F à environ 159 °F.
Patent EP-1214156-A2 (EP)
Inventor: EXNER HUBERTUS
IPC: B07B13/07
Filed: 2000-09-20
Abstract: The invention relates to a sorting device for particles (P) of differing sizes, comprising at least two conveying units (1, 2, 3), whereby the particles which are to be sorted are fed upstream to said units. A height gradation (H) of the planes of conveyance is provided between at least two conveyor units that are arranged successively in the direction of conveyance (X), creating a horizontal space or gap therebetween. The products, for example, which have been transported by conveyer units placed upstream, tip over the end of the upstream conveyor unit and fall onto the downstream conveyor unit.
Patent EP-1128143-A2 (EP)
Inventor: BERTOLACCINI ANDREA
IPC: F25D29/00
Filed: 2001-01-11
Abstract: Refrigeration apparatus with an evaporator (1), a probe (8) firmly mounted
against said evaporator (1) and associated to a respective thermostat,
comprising a bracket (3) provided with a first (4) and a second portion (5) capable of
being closed elastically in a "book-like" manner, in which the inner
closable surface of the bracket (3), which is coupled to the evaporator (1),
accommodates in a proper recess (6) thereof a portion of the probe (8). The
evaporator (1) is provided with appropriate perforations (10) and said bracket (3) is
provided with means (9) adapted to enable it to engage said perforations (10)
without any need for additional fastening members. These means are
constituted by at least a wedge-shaped hook-on element (9) protruding
externally from one of said portions (4,5) of the bracket, oriented parallel to the
latter in the terminal portion thereof, and adapted to get removably
inserted in a respective one of said perforations (10).
Patent EP-1130269-A2 (EP)
Inventor: FAHRENBACH PETER
IPC: F04D19/04
Filed: 2001-02-06
Abstract: Pump has rotor (4) and stator (6) plates arranged alternately in series and distance rings (8) for stator plates forming stator packet with stator plates. An elastically deformable metal element (16) is arranged between at least two of distance rings and forms part of stator packet. An axial groove (14) machined into at least no distance ring accommodates an elastically deformable metal element.
Patent EP-1132378-A2 (EP)
Inventor: HANADA KAZUYUKI
IPC: C09D175/12
Filed: 2001-03-06
Abstract: Fluorine-containing diols represented by the following
formula (I) are provided:
 
wherein R f  represents a perfluoroalkyl or perfluoroalkenyl
group having 1 to 20 carbon atoms; X represents a substituted
or unsubstituted alkylene group having 1 to 10 carbon atoms,
a substituted or unsubstituted alkenylene group represented by
-CH=CH-(CH 2 ) n - in which n stands for an integer of from 1 to
10, or
 
in which n stands for an integer of from
0 to 6; Y represents a direct bond, -O-, -NH-, or -R 0 -NH- in
which R 0  is an alkylene group having 1 to 6 carbon atoms; Z
represents a direct bond or -N(R')R- in which R is an alkylene
group having 1 to 20 carbon atoms and R' is a hydrogen atom or
an alkyl group having 1 to 6 carbon atoms; R 1  and R 2  each
independently represent a divalent organic group; and R 3 
represents a residual group of an aliphatic, alicyclic or
aromatic diisocyanate. These fluorine-containing diols are
useful for the production of polyurethanes.
Patent EP-1134493-A2 (EP)
Inventor: USHIJIMA KAZUFUMI
IPC: H05B6/70
Filed: 2001-02-23
Abstract: In a waveguide 11 provided with a magnetron 12, a container
13 made of quartz glass and containing a porous body 14 is placed.
The container 13 is connected to a water supply pipe 15, a steam
delivery pipe 16 and a drain pipe 17. Pure water regulated at
a preset flow rate by a flow control valve 18 drops on the upper
face of the porous body 14, and infiltrates into the porous body
14. When the magnetron 12 sends out microwave radiation to the
waveguide 11, the pure water contained in the porous body 14 is
heated by the microwave, and instantaneously evaporates. The steam
of pure water escapes from every surface of the porous body 14
and delivered through the steam delivery pipe 16. An appropriate
control of the flow rate of the pure water by the flow control
valve 18 and the output power of the magnetron 12 can make an
appropriate control of the flow rate of the steam, so that all
the pure water supplied to the porous body 14 is converted to
steam.
Patent EP-1136441-A2 (EP)
Inventor: BAUMANN FRANK DR
IPC: H01M8/0662
Filed: 2001-03-17
Abstract: In the catalytic conversion of carbon monoxide (CO) in a gas mixture containing water to carbon dioxide (CO2) and hydrogen (H2) (CO conversion) by passing the gas mixture over a shift catalyst at the temperature for CO conversion, the shift catalyst is based on noble metals in the form of a coating on an inert carrier.
Patent EP-1162063-A2 (EP)
Inventor: KAWAUCHI IKUO
IPC: G03F7/039
Filed: 2001-06-05
Abstract: A positive planographic printing plate which has high
sensitivity, limited reduction in sensitivity over time and
high stability over time. The positive planographic printing
plate has a light-sensitive layer formed on a support. The
light-sensitive layer includes a light-sensitive image-forming
material and a material which absorbs light and generates heat.
The light-sensitive image-forming material contains a novolac
resin having a xylenol monomer. It is preferable that, if a
proportion of the xylenol-containing novolac resin in
alkali-soluble resin that forms the light-sensitive layer is
Y% by weight and a content of the xylenol monomer in the novolac
resin is X% by weight, X × Y is 500 or more (X × Y ≧ 500).
Patent EP-1178551-A2 (EP)
Inventor: CHRISTEN ANDREAS
IPC: H01M8/249
Filed: 2001-07-18
Abstract: The fuel cell system is controlled solely by switching individual cells or stacks on and off.. Current density matching present demand may be controlled in addition. In this way, electrical and/or thermal loading of the fuel cell system is controlled. An Independent claim is included for equipment carrying out the method, providing for series and/or parallel connection, switching on and/off and cell shorting as appropriate.
Patent EP-1175969-A2 (EP)
Inventor: YAMAMOTO HIROKI
IPC: B25C1/00
Filed: 2001-07-24
Abstract: A nailing machine includes a nose member disposed
in the leading end portion of a main body of the nailing
machine for driving the leading nail of stick-shaped
connected nails supplied thereto, and a magazine mounted in
an opening formed in the side surface of the nose member
for sequentially supplying the connected nails to the nose
member. When the magazine is fit to the nose member, an
elastic member is pressed in into a clearance provided
between the nose member and the magazine.
Patent EP-1188656-A2 (EP)
Inventor: OZEKI TAKASHI
IPC: B62K5/08
Filed: 2001-08-14
Abstract: In a rear wheel suspension system (30) in
a four-wheeled vehicle (10) wherein a joint member (31) is
mounted in a rear portion of a vehicle body (11) with a
pair of left and right front wheels (13,14) secured
thereto, the joint member (31) comprising a roll shaft (41)
extending substantially in the longitudinal direction of
the vehicle body and a vertical swing shaft (36) extending
in the transverse direction of the vehicle body, and a
power unit (32) which supports rear wheels (26) and (27) is
connected to a rear portion of the joint member (31),
thereby allowing the power unit (32) to be secured to the
vehicle body (11) rollably and swingably, the roll shaft (41)
is mounted so that a front end portion (41a) thereof is
positioned lower than a rear end portion (41b) thereof. 
     It is possible to easily attain the reduction
in weight of the vehicle, set a weight distribution of
the vehicle freely, and improve the vehicular design
freedom. Besides, such rear wheel steering rods and rod
connecting members as in the prior art are not needed and
therefore it is possible to decrease the number of
components used in the rear wheel suspension system.