baber/WOPTO huggingface dataset:
Patent AU-2015328163-B2 (AU)
Title: Multiple-variable IL-2 dose regimen for treating immune disorders
Inventor: KORETH JOHN
IPC: A61K38/20
Filed: 2015-10-07
Granted: 2020-10-15
Abstract: The present invention is based, in part, on the identification of iiicihods of using multiple-variable IL-2 doses for identifying, assessing, preventing, and treating immune disorders.
Patent AU-2015346009-B2 (AU)
Title: Biological sample collection and storage assembly
Inventor: HOPPER WILLIAM R
IPC: A01N1/02
Filed: 2015-11-13
Granted: 2020-07-23
Abstract: A biological sample collection and storage assembly, including: at least one filtering component; and an absorbent storage component; wherein the at least one filtering component is configured to filter a received biological sample in fluid form containing free cells and other biological components to separate the free cells from the other biological components such that the other biological components flow to the absorbent storage component for subsequent testing or analysis.
Patent AU-2015380736-B2 (AU)
Title: Dispenser with metal sheet outer surface, support structure, metal sheet and manufacturing method
Inventor: ARLEMARK MALKUS
IPC: A47K10/16
Filed: 2015-01-29
Granted: 2019-02-14
Abstract: The invention relates to a dispenser (1) for storing and dispensing a hygiene product. The dispenser (1) comprises at least one wall (5-10) having a support structure (21) made at least mainly of plastic material, and at least one metal sheet (20) attached on an outer side of the support structure (21). The at least one metal sheet (20) includes a rim (30) extending along at least a part of a peripheral side edge (29) of the at least one metal sheet (20) and a plurality of fastening tabs (23, 24) distributed around the peripheral side edge (29) of the at least one metal sheet (20). The support structure (21) includes at least one groove (31) arranged to receive the rim (30) and a plurality of apertures (25, 26) configured to receive the fastening tabs (23, 24). The invention further relates to a method for manufacturing the dispenser (1), the support structure (21) with groove (31) and apertures (25, 26) as such, and the metal sheet (20) with a rim (30) and fastening tabs (23, 24) as such.
Patent AU-2016204739-B2 (AU)
Title: Stable and soluble antibodies inhibiting TNFalpha
Inventor: EWERT STEFAN
IPC: G01N33/53
Filed: 2016-07-08
Granted: 2017-07-20
Abstract: The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNFa, which comprise specific light chain and heavy chain sequences that are optimized for stability, solubility, in vitro and in vivo binding of TNFo, and low immunogenicity. Said antibodies are designed for the diagnosis and/or treatment of TNFa related disorders. The nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.
Patent AU-2016206096-B2 (AU)
Title: Intumescent composition comprising a silicate modifed epoxy resin
Inventor: KITTLE KEVIN JEFFREY
IPC: C09D5/00
Filed: 2016-01-04
Granted: 2019-03-14
Abstract: The present invention relates to an intumescent coating composition comprising (a) the reaction product of a tetra-alkoxylorthosilicate or partially condensed oligomer thereof and an epoxy resin containing hydroxyl groups, wherein the alkoxy groups are independently selected from C
Patent AU-2016208161-B2 (AU)
Title: IL-17A-binding polypeptides
Inventor: FREJD FREDRIK
IPC: A61K38/20
Filed: 2016-01-12
Granted: 2020-01-16
Abstract: The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-17A (IL-17A), and provides an IL-17A binding polypeptide comprising the sequence EX
Patent AU-2016233795-B2 (AU)
Title: Self-contained time division duplex (TDD) subframe structure
Inventor: MUKKAVILLI KRISHNA KIRAN
IPC: H04W72/04
Filed: 2016-02-26
Granted: 2019-11-14
Abstract: Aspects of the present disclosure provide a subframe structure for time division duplex (TDD) carriers that can be entirely self-contained. That is, information transmitted on a TDD carrier may be grouped into subframes, where each subframe provides communication in both directions (e.g., uplink and downlink) in a suitable fashion to enable such communication without needing any further information in another subframe. For example, a single subframe may include scheduling information, data information corresponding to the scheduling information, and acknowledgment information corresponding to the data information.
Patent AU-2016242115-B2 (AU)
Title: Regenerative railway braking system
Inventor: PYPER ANDREAS
IPC: B61C9/50
Filed: 2016-04-01
Granted: 2021-05-27
Abstract: This invention concerns a regenerative braking system for installation on a bogie of a railway vehicle. The regenerative system includes an energy storage system for storing energy in mechanical or kinetic form, a transmission system and a control unit. The transmission system is selectively operable between different modes including a braking mode in which it transmits mechanical or kinetic energy from an axle of the bogie to the energy storage system and a drive mode in which it transmits mechanical or kinetic energy from the energy storage system to the axle of the bogie. The control unit is, in use, in communication with a prime mover of the train and the transmission system so as to receive control signals from the prime mover and automatically operate the mode of the transmission system in response to the control signals. The invention also concerns a railway bogie including a regenerative braking system, a regenerative energy management system and a method of operating the regenerative braking system.
Patent AU-2016244182-B2 (AU)
Title: Methods for monitoring cd4+ t-helper type 1 response in cancer and immune restoration
Inventor: CZERNIECKI BRIAN J
IPC: C12N5/078
Filed: 2016-10-10
Granted: 2018-12-20
Abstract: A method for diagnosing or treating a mammalian subject having, or at risk of developing cancer, comprising: generating a circulating anti-cancer CD4+ ThI response from antigen presenting cells or their precursors and CD4+ T-cells from a sample of said subject's blood which causes secretion of interferon-gamma ("IFN-y"); and detecting said anti-cancer CD4+ ThI response to determine if said response is depressed. A method for restoring HER2-specific CD4+ Th1 immune response in a HER2-positive breast cancer patient in need thereof, comprising: administering to said patient a therapeutically effective amount of a dendritic cell ("DC") vaccine comprising autologous DCs pulsed with HER2-derived MHC class II binding peptides ("DC vaccination") to elevate said patient's anti-HER2 CD4+ Th1 response; and measuring said anti-HER2 Th1 response of said patient pre- and post-DC vaccination to determine the amount of increase in said response. ik jon [C"? No 15 LJ~ cyc ThTh 'KR jcloy n 'n ..h ...a' 11L~O"T~ I: "Pit.______ 71f "1 ~Tt AL'tu r 0 iK 2 ~t13 C MV~~ ~ sxt~~ Ltc !9Q, 3ZNK$(C t ua~~~ qra a I 'N N"" "N" "N' "N"
Patent AU-2016311131-B2 (AU)
Title: Mineral compositions for stimulating the carbohydrate metabolism
Inventor: WERNER TANJA
IPC: A61K33/30
Filed: 2016-08-17
Granted: 2021-06-24
Abstract: The invention relates to novel applications of mixtures of three or more citrate salts, comprising magnesium citrate, the mixture of two, three or more citrate salts additionally comprising calcium citrate and/or zinc citrate, in particular to stimulate or boost the carbohydrate metabolism, preferably the glucose metabolism, in particular to stimulate or boost the cellular energy metabolism.
Patent AU-2016315424-B2 (AU)
Title: Apparatus and method for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample
Inventor: POL TOMASZ
IPC: G01N21/90
Filed: 2016-08-19
Granted: 2021-09-16
Abstract: Apparatuses and methods are disclosed for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample. A method includes moving a reference sample receptacle carrier of an apparatus to position a first reference sample receptacle received in the carrier at a second position in a light path, directing light from an illumination system to a detection system along the light path to perform a light-absorption measurement on a first reference sample at the second position, moving the carrier to position the first receptacle out of the light path, placing a test sample receptacle in a test sample receptacle holder of the apparatus in the light path at a first position different from the second position, and directing light along the light path to perform a light-absorption measurement on a test sample in the test sample receptacle holder at the first position.
Patent AU-2016330005-B2 (AU)
Title: Security print media and method of manufacture thereof
Inventor: KEEN ALAN
IPC: B42D25/24
Filed: 2016-09-27
Granted: 2021-11-25
Abstract: A security print medium is disclosed for forming security documents therefrom. The security print medium comprises a transparent or translucent polymer substrate having first and second opposing surfaces, and a plurality of overlapping opacifying layers disposed on the first and/or second surfaces of the polymer substrate, each of the opacifying layers being a layer of semi-opaque material disposed over substantially the whole area of the polymer substrate. In at least a region of the substrate, a multi-tonal image is exhibited by the plurality of overlapping opacifying layers in combination with one another, at least when the security print medium is viewed in transmitted light. Each of the plurality of overlapping opacifying layers has gap(s) in which the semi-opaque material of the layer is absent, the gap(s) of each layer being defined in accordance with a different respective sub-image, the sub-images in combination defining the multi- tonal image, wherein either all the sub-images are different negative image versions of the multi-tonal image or all the sub-images are different positive image versions of the multi-tonal image. As a result, the number of opacifying layers overlapping one another at any one location varies across the substrate, the resulting variation in optical density of the plurality of overlapping opacifying layers in combination with one another giving rise to the multiple tones of the multi-tonal image.
Patent AU-2016383713-B2 (AU)
Title: Viscosity and stability modified ultrasound gel
Inventor: SCURTESCU CRISTIAN
IPC: A61K49/22
Filed: 2016-12-09
Granted: 2023-10-12
Abstract: An ultrasound gel is provided for use with internal ultrasound imaging and/or therapy. The gel can have acoustic properties that can closely match a soft tissue to be imaged/treated and can be of a high viscosity that is maintained at body temperature. In some embodiments, the gel can act as a lubricant and, although water based, can be hydrophobic and not dissolve in bodily fluids. In some embodiments, the gel can be sterile, safe for ingestion, safe for application over mucous membranes, and include a preservative. In order to achieve sterility while maintaining a desired viscosity range, the gel can include a viscosity stabilising agent such as a viscosity protection agent for protection from radiation induced breakdown. In some embodiments, methods of altering or maintaining the viscosity of a gel is provided.
Patent AU-2017224250-B2 (AU)
Title: Shoulder arthroplasty implant system
Inventor: HATZIDAKIS ARMODIOS M
IPC: A61F2/40
Filed: 2017-02-28
Granted: 2022-01-13
Abstract: An implant for shoulder arthroplasty includes a stem and optionally a head component or a cup component. The stem is sized and shaped to fit into an intramedullary canal of the humerus. The proximal portion of the stem has a concave taper and the distal portion of the stem has a taper. The distal taper includes an anterior-posterior taper and a medial-lateral taper. The shape of the stem loads the metaphysis of the humerus with a greater load than the load applied to the diaphysis of the humerus.
Patent AU-2017247133-B2 (AU)
Title: Isothermal amplification components and processes
Inventor: MILLER ANDREW P
IPC: C12Q1/68
Filed: 2017-03-06
Granted: 2023-02-09
Abstract: The technology relates in part to methods and compositions for isothermal amplification of nucleic acids.
Patent AU-2017276263-B2 (AU)
Title: Methods for enriching primitive gut tube
Inventor: KARANU FRANCIS
IPC: C12Q1/68
Filed: 2017-12-14
Granted: 2019-07-11
Abstract: Abstract The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing unique surface markers. The present invention also provides methods to enrich or sort cells expressing markers characteristic of the pancreatic endocrine lineage. The present invention also provides methods to deplete cells that may contaminate populations of cells expressing markers characteristic of the pancreatic endocrine lineage formed by the methods of the present invention, thereby reducing the incidence of tumor formation in vivo following transplantation.
Patent AU-2017308158-B2 (AU)
Title: Alpha and gamma-D polyglutamated antifolates and uses thereof
Inventor: NIYIKIZA CLET
IPC: A61K45/06
Filed: 2017-08-12
Granted: 2023-08-10
Abstract: The disclosure relates generally to polyglutamated antifolates, formulations containing liposomes filled with alpha or D-gamma polyglutamated antifolates, methods of making the polyglutamated antifolates and liposome containing formulations, and methods of using polyglutamated antifolates and liposome containing formulations to treat hyerproliferative disorders (
Patent AU-2017341825-B2 (AU)
Title: Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders
Inventor: KOMERS RADKO
IPC: A61K31/422
Filed: 2017-10-13
Granted: 2023-06-01
Abstract: Methods of treatment comprising administering a compound having structure (I), N O O2 S NH N N O O, (I) or a pharmaceutically acceptable salt thereof, or administering a pharmaceutical composition comprising the compound of structure (I) or pharmaceutically acceptable salt thereof, are provided.
Patent AU-2017361383-B2 (AU)
Title: Material supply system with a valve assembly and a base assembly provided with an actuator
Inventor: DOBIZL KENNETH THOMAS
IPC: B65G69/18
Filed: 2017-11-16
Granted: 2023-10-05
Abstract: A material supply assembly includes a valve assembly (230) having an outer valve member and an inner valve member rotatable relative to the outer valve member. A base assembly (300) includes an base structure and an actuator. An engagement structure is operative between the outer valve member and the actuator to prevent relative movement between the outer valve member and the actuator. A locking structure is operative between the inner valve member and the base structure to prevent relative movement between the inner valve member and the base structure. Movement of the actuator relative to the base structure moves the outer valve member relative to the inner valve member to operate the valve assembly.
Patent AU-2017363973-B2 (AU)
Title: Compositions and methods for the treatment of oral infectious diseases
Inventor: KANDULA MAHESH
IPC: A61K31/00
Filed: 2017-04-19
Granted: 2022-03-03
Abstract: The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV, formula V, formula VI, formula VII, formula VIII, formula IX, formula X, formula XI and formula XII and, the methods for the treatment of oral infectious diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, lozenge, spray, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of oral infectious diseases.
Patent AU-2017377036-B2 (AU)
Title: Anti-OX40 antibodies and their uses
Inventor: HARDING FIONA A
IPC: C07K16/28
Filed: 2017-12-15
Granted: 2022-06-23
Abstract: The present disclosure provides novel anti-OX40 antibodies, compositions including the antibodies, nucleic acids encoding the antibodies, and methods of making and using the same.
Patent AU-2017420421-B2 (AU)
Title: A haemostatic agent delivery device
Inventor: NG HONG GUAN
IPC: A61B17/03
Filed: 2017-06-22
Granted: 2021-02-25
Abstract: The present invention relates to a haemostatic agent delivery device (1) comprising an external tube (2) having a bridge portion (5) that has a first groove (6a) and second groove (6b) mounted on each end of the bridge (5), a gripping means (4) having a pair of finger holes for receiving user's fingers at the proximal end, and a longitudinal groove (12) at the rear surface of the tube terminating with a tubular portion (7) at the distal end; and an internal tube (3) having a singular gripping portion (9), an extended portion (14) beneath the gripping portion (9) that terminates with a resilient end that has an overlapping protrusion (10) as a locking means and a connecting means (11) at its proximal end for connecting to a suction applying device; wherein, when in use, the overlapping protrusion (10) interlocks with the first groove (6a) for loading of haemostatic agent into the device whereas the overlapping protrusion (10) interlocks with the second groove (6b) for delivering and compressing the haemostatic agent at the bleeding site.
Patent AU-2017422789-B2 (AU)
Title: Gate valve and gate valve control method
Inventor: KOU ZIMING
IPC: F16K47/02
Filed: 2017-07-14
Granted: 2020-12-24
Abstract: A gate valve and a gate valve control method; the gate valve comprises a gate (13, 23), a gate valve control device (11, 21), and a hydraulic power device (12, 22) for driving the gate (13, 23) to open and close; the gate valve control device (11, 21) comprises: a control component which controls movement of the hydraulic power device (12, 22), and a detecting component which detects the state of the gate valve; the detecting component is configured to detect actual state data of the gate valve at preset time intervals; the control component is configured to adjust control parameters inputted into the hydraulic power device (12, 22) according to the actual state data detected by the detecting component, until the actual state data conforms to preset state data.
Patent AU-2018200714-B2 (AU)
Title: Monolithic ultrasonic imaging devices, systems and methods
Inventor: ROTHBERG JONATHAN M
IPC: A61B8/14
Filed: 2018-01-31
Granted: 2019-06-13
Abstract: An ultrasound device, comprising: at least first and second ultrasonic transducer elements; a first transmit control circuit comprising: a first pulser coupled to the first ultrasonic transducer element so as to drive the first ultrasonic transducer element so that the first ultrasonic transducer element emits an ultrasonic pulse; a first waveform generator coupled to the first pulser to provide a first waveform to the first pulser in response to receipt, by the first transmit control circuit, of a transmit enable signal generated by a timing and control circuit; and at least one first component that impacts a length of a first delay between when the first transmit control circuit receives the transmit enable signal and when the first waveform is applied to the first pulser; a second transmit control circuit comprising: a second pulser coupled to the second ultrasonic transducer element so as to drive the second ultrasonic transducer element so that the second ultrasonic transducer element emits an ultrasonic pulse; a second waveform generator coupled to the second pulser to provide a second waveform to the second pulser in response to receipt, by the second transmit control circuit, of the transmit enable signal generated by the timing and control circuit; and at least one second component that impacts a length of a second delay between when the second transmit control circuit receives the transmit enable signal and when the second waveform is applied to the second pulser; wherein the at least one first component is configured differently than the at least one second component, so that the length of the second delay is different than the length of the first delay, and wherein the first and second ultrasonic transducer elements, the first transmit control circuit, and the second transmit control circuit are formed on a single solid state semiconductor die. c-o
Patent AU-2018204228-B2 (AU)
Title: Methods, kits, and systems for multiplexed detection of target molecules and uses thereof
Inventor: WEISSLEDER RALPH
IPC: C12P19/34
Filed: 2018-06-14
Granted: 2020-04-16
Abstract: Described herein are methods, compositions, kits and systems for multiplexed detection of target molecules from a sample. In some embodiments, the methods, compositions, kits and systems can be used to perform multiplexed protein analysis of a sample (e.g., a sample comprising a small number of cells or a single- cell sample). In some embodiments, the same sample subjected to a multiplexed protein analysis using the methods, compositions, kits and systems described herein can also be subjected to a nucleic acid (e.g., RNAs, microRNAs, and/or DNA) analysis, thereby creating an in- tegrated expression profiling from a limited amount of sample.
Patent AU-2018236343-B2 (AU)
Title: Identification of shrink-wrapped objects
Inventor: CHRISTMAN RUSSELL T
IPC: B65B53/02
Filed: 2018-03-15
Granted: 2023-10-12
Abstract: An object can be heat-shrinkable packaged by placing an object inside of heat-shrinkable film, sealing the heat-shrinkable film around the object to form a heat-shrinkable package, coupling a first portion of a label to the heat-shrinkable package, and causing the heat-shrinkable film to shrink into heat-shrunk film and the heat-shrinkable package to form into a heat-shrunk package. The label includes an identifier on a second portion of the label. The label remains coupled to the heat-shrunk film after the heat-shrinkable film is caused to shrink into heat-shrunk film. The second portion of the label remains substantially undeformed after the heat-shrinkable film is caused to shrink into heat-shrunk film.
Patent AU-2018251212-B2 (AU)
Title: Carbon dioxide underwater delivery device and supplementation system
Inventor: BABCOCK GLEN
IPC: A01N63/30
Filed: 2018-04-16
Granted: 2022-09-08
Abstract: A delivery device and system to supplement CO
Patent AU-2018260564-B2 (AU)
Title: Synchronous belt with unidirectional fabric reinforcement
Inventor: MCNAMEE PATRICK JOSEPH
IPC: F16G1/28
Filed: 2018-04-27
Granted: 2020-10-01
Abstract: A synchronous belt having a tensile member layer with a tensile member embedded in an elastomeric body, a toothed surface with a plurality of regularly spaced, transverse teeth protruding from the body, a jacket covering the toothed surface, and a unidirectional fabric layer suspended in the belt between the jacket and the tensile member layer and following the approximate contour of the jacket.