baber/WOPTO huggingface dataset:
Patent SG-11201803722X-A (SG)
Title: Azeotrope-like compositions comprising z-1,1,1,4,4,4-hexafluoro-2-butene
Inventor: KIKUCHI HIDEAKI
IPC: C09K5/04
Filed: 2016-12-07
Abstract: 12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, -, Organization IIIMIOH0110101011111 HO 111110111010111111101111111101110111110 ill OEN International Bureau .. .... ..Yejd (10) International Publication Number International Publication Date ..... ....r .„.1 WO 2017/105959 Al 22 June 2017(22.06.2017) WIPO I PCT (51) (21) (22) (25) (26) (30) (71) (72) (74) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C07C 31/10 (2006.01) C09K 5/04 (2006.01) kind of national protection available): AE, AG, AL, AM, C07C 21/18 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/US2016/065358 HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, International Filing Date: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 7 December 2016 (07.12.2016) MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, Filing Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, Publication Language: English TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Priority Data: 2015-242867 14 December 2015 (14.12.2015) JP (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, Applicant: DUPONT-MITSUI FLUOROCHEMICALS GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, CO. LTD [JP/JP]; 4th FLOOR, CHIYODA BLDG, 1-5- TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, 18, SARUGAKU-CHO 1-CHOME, Chiyoda-ku, Tokyo TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, 101-0064 (JP). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Inventors: KIKUCHI, Hideaki; 3600 MIHO, SHIMUZU- KU, Shizuoka-shi, Shizuoka, Shizuoka 4248631 (JP). SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, MATSUMOTO, Takanori; 3600 MIHO, SHIMIZU-KU, GW, KM, ML, MR, NE, SN, TD, TG). Shizuoka-shi, Shizuoka, Shizuoka 424-8631 (JP). Published: Agent: LEACH, Douglas R.; Patent Legal Group, 7028-1, — with international search report (Art. 21(3)) 1007 Market Street, Wilmington, Delaware 19801 (US). = (54) Title: AZEOTROPE-LIKE COMPOSITIONS COMPRISING Z-1,1,1,4,4,4-HEXAFLUOR0-2-BUTENE FIG. 1 Z - HF0 - 1336mzzm - IPA Boiling Curve 38.0 (57) : The present invention aims to solve the above mentioned problems by providing a new azeotrope-like composi- tion that can be used for a wide range of in- dustrial purposes. The provision of an azeotrope-like composition including 93.0 - 99.0 weight percent Z-1,1,1,4,4,4-hexa- fluoro-2-buteine and 0.1 - 7 weight percent isopropanol. 10 37.5 37.0 36.5 36.0 Boiling 35.5 Point [°C] 35.0 34.5 1-1 kir) 0 \ kir) 0 1-1 1-1 0 ei 34.0 0 \ 33.5 ... 33.0, 2 4 6 8 IPA Concentration [wt%] O
Patent SG-11201805148W-A (SG)
Title: Method and system for calculating, in real-time, the duration of autonomy of a non-refrigerated tank containing lng
Inventor: BEN BELGACEM-STREK MICHEL
IPC: F17C13/02
Filed: 2016-12-16
Abstract: This invention relates to a method and a system for calculating real-time duration autonomy a 5 non-refrigerated tank containing natural gas comprising a liquefied gas layer a natural gas (GNG) layer. This invention also relates to a system for calculating, in real time, according to the method of the the of of non- 10 refrigerated tank, as well as a vehicle comprising an NG tank and a system according to the invention. FIG 3.
Patent SG-11201807538P-A (SG)
Title: Crispr-cpf1-related methods, compositions and components for cancer immunotherapy
Inventor: WELSTEAD GORDON
IPC: C12N15/63
Filed: 2017-03-03
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 1111101110111 11010101111101 RIMINI III International Bureau .. .... ..Yejd .... ...,,, (10) International Publication Number (43) International Publication Date WO 2017/152015 Al 8 September 2017 (08.09.2017) WIP0 I PCT (51) (21) (22) (25) (26) (30) (71) (72) (74) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C12N 15/113 (2010.01) C12N 15/63 (2006.01) kind of national protection available): AE, AG, AL, AM, C12N 9/22 (2006.01) A61P 35/00 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C12N 15/09 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, PCT/US2017/020598 KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, International Filing Date: MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 3 March 2017 (03.03.2017) NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, Filing Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, Publication Language: English ZA, ZM, ZW. Priority Data: (84) Designated States (unless otherwise indicated, for every 62/304,057 4 March 2016 (04.03.2016) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, Applicant: EDITAS MEDICINE, INC. [US/US]; 11 TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, Hurley Street, Cambridge, MA 02141 (US). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, Inventors: WELSTEAD, Gordon, Grant; 20 Andrew DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Street, Cambridge, MA 02139 (US). JAYARAM, Hari- SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, haran; 184 Raymond Street, Apt. 4, Cambridge, MA 02140 (US). WANG, Tongyao; 10 Summer Street, Apt. GW, KM, ML, MR, NE, SN, TD, TG). 309, Malden, MA 02148 (US). ZURIS, John, Anthony; Published: 113 Harvard Street, Apt. 7, Cambridge, MA 02139 (US). — BORGES, Christopher; 21 Cumberland Road, Reading, with international search report (Art. 21(3)) MA 01867 (US). — with sequence listing part of description (Rule 5.2(a)) Agents: LENDARIS, Steven P. et al.; Baker Botts LLP, 30 Rockefeller Plaza, New York, NY 10112-4498 (US). = APY Title: CRISPR-CPF1-RELATED METHODS, COMPOSITIONS AND COMPONENTS FOR CANCER IMMUNOTHER- = (54) 1-1 in 11 © ei lun ,-1 IN 1-1 0 (57) ei Y Direct repeat domain FIG. 1 : CRISPR/Cpfl -related compositions and methods for treatment Targeting domain of cancer. 0
Patent SG-11201902638R-A (SG)
Title: File transmission method and apparatus
Inventor: PAN SHANJUN
IPC: H04L29/06
Filed: 2017-09-28
Abstract: File Transmission Method and Apparatus A method and an apparatus for file transmission are provided by the present application. The method may include receiving a file sending request initiated by a source user for a preset file; sending an approval message for the file sending request to an approval user corresponding to the source user when the source user does not have a transmission privilege for the preset file; and setting the preset file as an obtainable state for a target user corresponding to the file sending request in response to the approval message being approved by the approval user. The technical solutions of the present application can prevent an approval operation of a file from interrupting a communication process between users, help to simplify user operations, and improve the smoothness of the communication process. Fig. 3
Patent SG-11201906272R-A (SG)
Title: Data transmission method and communication device
Inventor: TANG HAI
IPC: H04W72/04
Filed: 2017-01-05
Abstract: DATA TRANSMISSION METHOD AND COMMUNICATION DEVICE Disclosed in the present application are a data transmission method and a communication device. The method comprises: determining transmission parameters for transmitting the current target transport block, the transmission parameters comprising a target modulation and coding scheme (MCS), the number of target physical resource blocks (PRBs), and information about PRB resource overhead; determining, according to the transmission parameters, the target transport block size (TBS) of the target transport block; and sending or receiving, according to the target TBS, the target transport block. Said method is able to determine, on the basis of different resource overhead, TBS information used for data transmission. (Fig. 2)
Patent AT-406536-B (AT)
Title: Device for positioning electronic circuits which are arranged on a film
Inventor: SCHWEITZER KARL ING
IPC: H05K13/02
Filed: 1998-02-17
Granted: 2000-06-26
Abstract: Device for positioning electronic circuits which are arranged on a film, for example chips, on a printed circuit board, ceramic substrate or the like using the flip-chip method, which is highly convenient to use due to programmability and reproducibility of the various settings, and is distinguished by simple construction. The chips 1 which are mounted on a film 2 are arranged in the access area of a suction needle 3, with push-out needles 4 being provided under the film 2. The chip 1 is lifted off by means of an exact movement, synchronously, vertically and in a straight line, of the push-out needles 4 and suction needle 3. Once the chip 1 has been transferred by the suction needle 3 from the film 2, the suction needle 3 is pivoted through 180 via a rotary mechanism 7 which is connected to a drive 9 via a belt drive 8. The chip 1 is now transferred for positioning on a printed circuit board 11 by a further suction needle 10, which has four degrees of freedom. Before the chip 1 is positioned on the printed circuit board 11, the chip 1 is measured by a measurement camera 13, and the printed circuit board 11 is measured via the measurement camera 14. The two measurement cameras 13, 14 are connected to a computer 15. The two measurement cameras 13, 14 are calibrated by overlaying the two images, with this calibrated position likewise being stored in the computer 15. Any error from the calibrated position which is found in the computer 15 is compensated for by computer-aided control for the suction needle 10. <IMAGE>
Patent AT-393990-B (AT)
Title: Mixing apparatus with an intake head for at least two pourable materials
IPC: B01F3/18
Filed: 1990-04-06
Granted: 1992-01-10
Abstract: To ensure reliable switching over of an intake head for a mixing apparatus to one of at least two intake lines 5, a switching-over device 4 is proposed, comprising a slide plate 7 between two guiding walls 6 which bear with a sealing effect against the said slide plate and have through-openings 9 which connect the intake lines 5 to a collecting space connected to a suction line 2 and one of the said openings is alternately exposed by the slide plate 7, which is provided with at least one through- opening 10. <IMAGE>
Patent HU-195312-B (HU)
Title: Working wall for open-hearth furnaces of oxygen enriched air blast
Inventor: BARCZI LASZLO
IPC: B22D1/00
Filed: 1986-01-30
Abstract: The operating wall is made up of brick elements at least 400 mm, but preferably 600-900 mm long, laid at right angles to the furnace lining, and of compacted or cast monolithic wall max. 800 mm, but pref. 300-500 mm thick. - One pref. form of the brick elements contains carbon and/or is impregnated with tar. The blow pipes are located in holes through the bricks. These holes have a dia. max. 10 mm greater than the outside dia. of the blow tubes. The gap is filled with fine grained magnesite mortar. The opening for each pipe generally passes through several bricks. - The operating wall is provided with water cooling. This may be in the form of cooling pipes, located between the furnace lining and the brick wall, in the compacted or cast layer, or in the form of a cooling system outside the furnace lining, which in some cases contains cooling 'bags'.
Patent HU-198421-B (HU)
Title: Method for controlling the deflection of steerable articulated vehicles particularly articulated buses
Inventor: REICHL BERNHARD
IPC: B62D53/00
Filed: 1984-02-14
Abstract: A buckling protection control system for articulated vehicles, especially for articulated buses is disclosed. Double acting piston cylinder units are interposed between vehicular sections at the hinged connection therebetween to forceably dampen and control the relative angular movement of the vehicular sections during driving of the vehicle. In addition to controlling the buckling movements during proper driver operation of the vehicle, the control system of the invention includes an arrangement for responding to situations where a driver, as a result of a panic reaction, sharply or rapidly steers the vehicle. For this purpose, the invention includes a computer control system which determines a maximum buckling angle value K-max(V) which is dependent on the vehicle velocity V. Irrespective of other driving conditions, the buckling angle is prevented from exceeding this maximum buckling angle K-max(V).
Patent HU-209801-B (HU)
Title: Fungicidal composition containing aryl-propyl- amines and process for preparation of the active ingredient
Inventor: CAMAGGI GIOVANNI
IPC: C07D213/643
Filed: 1991-03-01
Abstract: Disclosed are compounds endowed with antifungal activity, said compounds having the general formula (I):
       
 wherein:
     R₁ and R₂,   among others, represent hydrogen, (C₁-C₆)-alkyl groups and groups Ar-B in which 
Ar 
is a (C₆-C₁₀)-(halo)-aryl group and 
B 
is an (alkyl)-(C₁-C₄)-alkylene group,   R₃   is a (C₁-C₃)-alkyl group;   R₄   represents halogen or (C₁-C₃)-(halo)-alkyl;   m   ranges from 0 to 4;   R',R'',   represent H, (C₁-C₃)-alkyl or halogen;   n   ranges from 0 to 3;   Y   represents an optionally substituted -CH=CH₂, (C₃-C₆)-cycloalkyl, 5- or 6-membered heterocyclic or silyl group.
Patent HU-198510-B (HU)
Title: Process for producing norcholanic acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient
Inventor: CHIODINI LAURA
IPC: C07J41/00
Filed: 1987-01-07
Abstract: Compounds (I) (either R1 = OH, C1-C4 alkoxy and R2 = H, C1-C4 alkyl, or R1 + R2 = a chemical bond; R3 = an aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being  alpha  or  beta : and either R4 = OH and R5 = H or R4 + R5 = a chemical bond) and their pharmaceutically acceptable salts are useful as antihypertensive agents. Their preparation and use as well as pharmaceutical compositions containing them are also described.
Patent HU-184421-B (HU)
Inventor: LEHOECZ ALFRED
IPC: A47G35/00
Filed: 1981-04-06
Abstract: A találmány szerinti műanyag tapétaszegély élben végződő szélekkel ellátott szalagként van kialakítva oly módon, hogy szélessége 0,3—0,8-ad részén periodikusan ismétlődő bordaszerű mintával van ellátva. A minta legalább egy, a szalag hossztengelyére merőleges vagy azzal tompaszöget bezáró bordát tartalmaz és a bordák közötti mélyedések helyén a szalag minimális vastagsága 0,1-0,8 mm. A tapétaszegély gyártása mind a hagyományos fa szegélylécekénél, mind a már ismert műanyag szegélyekénél egyszerűbb, termelékenyebb és olcsóbb. Felhasználásához előkészítés nem szükséges, folyamatosan szerelhető, illeszthető, rugalmassága lehetővé teszi, hogy bármilyen kis sugárban meghajlítható legyen, így éles sarkok, beugrások stb. mentén is felerősíthető anélkül, hogy darabolni kellene, sőt bizonyos mértékig saját síkjában is ívbe hajlítható.
Patent HU-197843-B (HU)
Title: Process for producing pharmaceutical compositions comprising 2-alkoxy-n-(1-azabicyclo/2.2.2/oct-3-yl)-benzamide-n-oxide derivatives
Inventor: TENG LINA C
IPC: C07D453/02
Filed: 1987-03-04
Abstract: Compounds for controlling emesis caused by anticancer drugs such as 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides have the formula: …<CHEM>… wherein R1 is a loweralkyl group and R2 represents hydrogen, halo, 4,5-benzo, methylsulphonyl loweralkoxy or amino group and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof.
Patent HU-190075-B (HU)
Inventor: FEKETE GYOERGY
IPC: F16B5/02
Filed: 1983-03-22
Abstract: A különösen installációs rendszerek panelekből
való kialakítására szolgáló kapcsolóelemek
az összekapcsolandó elemek találkozásában,
illetve akörül helyezkednek cl, s mind
egymáshoz, mind az összekapcsolandó elemekhez
rögzíthetők. Maga a kapcsolóelem egy
vagy több bilincselemből áll, amely(ek) az
összekapcsolandó elemek - pl, panelek - találkozási
vonala, mint középvonal körül kialakított,
alul és felül, azaz egymással átellenben
elhelyezkedő körives peremmel és ezzel
koncentrikus körives horonnyal, az említett
középvonal, mint tengely körül elhelyezkedő
hengeres Felfekvőfelülettel rendelkezik, továbbá
legalább két befogólapja van, melyek
közül legalább az egyik befogólap rögzitöelemet
tartalmaz, végül a bilincselemlek) körives
hornyaiba összefogó csavarok körives
peremei nyúlnak be, amely összefogó csavarok
hengeres külső felfekvőfelülettel vannak
kialakítva, s egymással csavarmenet útján
vannak összeerósitve.
Patent YU-48401-B (YU)
Title: Doboš kočnice
Inventor: EBBINGHAUS
IPC: F16D66/02
Filed: 1992-05-27
Abstract: DOBOŠ KOČNICE naznačen time, što je uz otvor (14) smešten u površini (7) za naleganje upušten, obilazni žleb (15), koji se prostire u aksijalnom pravcu najmanje do obloga (4) kočnice. - Prijava sadrži još 8 zavisnih zahteva.
Patent ZA-95547-B (ZA)
Title: Assay for the determination of protein in a biological sample
Inventor: ALBARELLA JAMES
IPC: G01N33/68
Filed: 1995-01-24
Abstract: The detection of protein is accomplished by using a test element containing a phenolsulfonephthalein protein error indicator a buffer and an aliphatic ether-polycarbonate present in an amount equal to or less than ten percent by weight.
Patent AT-398869-B (AT)
Title: Drive circuit for an electronic power switch
Inventor: ERTL JOHANN DIPL ING DR
IPC: H03K17/082
Filed: 1989-06-06
Granted: 1995-02-27
Abstract: For an electronic power switch 1 whose switching path is connected to a DC voltage in series with a load, a drive circuit is specified which is realized by a non-inverting amplifier 4, which has feedback via an inverting amplifier 7, and in the case of which the electronic power switch 1 itself is used as a controlling element. <IMAGE>
Patent AT-406662-B (AT)
IPC: B60R21/01
Filed: 1998-10-02
Granted: 2000-07-25
Abstract: The airbag unit has a strip or thread-like sensor medium (3) with coding and associated brake device (5) with brake action. The brake device can be a leaf spring pressing the sensing medium against a backing support. The sensing medium can be arranged zig-zag in a supply chamber or wound onto a coil.
Patent AT-406261-B (AT)
Title: Process for cleaning up wastewater
Inventor: GASSNER KURT
IPC: C02F3/12
Filed: 1997-11-20
Granted: 2000-03-27
Abstract: The present invention relates to a process for cleaning up wastewater in which the following steps are carried out repeatedly: - feed of wastewater into a reactor 1; - aeration of the reactor contents; - termination of the aeration in order to allow sludge to settle; removal of clarified water and sludge. An increase in throughput is achieved by means of the fact that the wastewater is fed into the region of a nozzle 12 which connects two chambers 8, 9 of the reactor 1 which are separated by a dividing wall 7, in order to cause a circulating flow between the chambers 8, 9 of the reactor by the feed of the wastewater. In addition, the invention relates to an apparatus for carrying out the process. <IMAGE>
Patent CA-1121648-B (CA)
Title: Process and composition for producing and  maintaining good color in fresh meat, fresh  poultry and fresh fish
Inventor: WOODRUFF RICHARD E
IPC: A23B4/00
Filed: 1981-07-23
Granted: 1982-04-13
Abstract: PROCESS AND COMPOSITION FOR PRODUCING AND    MAINTAINING GOOD COLOR IN FRESH MEAT, FRESH POULTRY AND FRESH FISH                             By Richard E. Woodruff and John H. Silliker ABSTRACT           Good color in fresh meat, fresh poultry,and fresh fish is established and maintained by subjecting such meat, poultry and fish to an atmosphere containing a low oxygen concentration to convert oxymyoglobin on the surface of the meat and poultry to reduced myoglobin, and both oxymyoglobin and oxyhemoglo-bin in fish to reduced myoglobin/hemoglobin, respectively, then subjecting the fresh meat, fresh poultry and fresh fish to a modified atmosphere containing a small amount of carbon monoxide to convert the reduced myoglobin to carboxymyoglobin to a depth of not more than about 0.375 inch below the surface of the meat and poultry, and to convert the reduced myoglobin/hemoglobin to reduced carboxymyoglobin/carboxyhemoglobin in the fish.          The modified atmosphere is a new composition of matter.           During or  after the conversion, the fresh meat, fresh poul-try and fresh fish may be maintained at temperatures above freezing in an atmosphere that contains more than about 10% carbon dioxide by volume to inhibit bacterial growth, or alternatively, the fresh meat, fresh poultry and fresh fish may be frozen and maintained frozen in normal air atmosphere.
Patent DK-165747-B (DK)
Inventor: UMEZAWA HAMAO
IPC: C07H15/252
Filed: 1985-07-02
Abstract: The present invention relates to novel anthracycline compounds, and a process for producing the same. The compounds have anti-tumor activities and can, therefore, be used as medicaments.
Patent DK-151417-B (DK)
Inventor: BURCHART JOACHIM
IPC: E05G7/00
Filed: 1981-10-06
Abstract: A money dispensing device for use in safes or the like which transfers money from a security area to a dispensing point. A powered drawer transfers money from the security area to the dispensing point. The dispensing point is provided with a door, which is automatically controlled, such that the door opens only when sensors indicate that the drawer has reached the end of the dispensing point, and after opening, the door closes only when sensors indicate that the drawer is empty.
Patent DK-159131-B (DK)
Inventor: BRAGULLA SIEGFRIED
IPC: A01N57/20
Filed: 1983-10-10
Abstract: This invention is directed to germicidal compositions comprising a germicidally effective amount of at least one alkyl monophosphonic acid having from 4 to 12 carbon atoms in the alkyl chain in admixture with one or more surfactants in acidic solution and to the use of such compositions in disinfecting surfaces.
Patent DK-150841-B (DK)
Inventor: RASMUSSEN JAN
IPC: A61B5/274
Filed: 1984-12-19
Abstract: A fixture for use in establishing electrical contact between a banana plug mounted on a cable and a snap fastener on a disposable skin electrode comprises a bottom flange provided with a sleeve adapted to receive the banana plug. A resiliently expandable through hole formed at the bottom of the fixture makes it possible to snap the fixture over the snap fastener of the skin electrode, with the through hole being of length so that the snap fastener will protrude into the passage and establish electrical contact with a banana plug inserted therein.
Patent FI-90762-B (FI)
Inventor: HEROLD PETER
IPC: C07C227/06
Filed: 1987-08-10
Granted: 1993-12-15
Abstract: A novel process and intermediates for the preparation of 5-amino-4-hydroxyvaleric acid derivatives of the formula 
<IMAGE>
 in which R<1> represents hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkyl(lower alkyl), aryl, aryl(lower alkyl) or the radical of a natural amino acid, R<2> represents hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkyl(lower alkyl), aryl, aryl(lower alkyl), amino, hydroxyl, mercapto, sulphinyl, sulphonyl or the radical of a natural amino acid and R<3> represents optionally substituted hydroxyl or amino, by sigmatropic rearrangement of a suitable allyl ester, halolactonisation of the  gamma , delta -unsaturated acid obtainable or a suitable derivative thereof, replacement of halogen by a nitrogen-containing nucleophile, lactone ring-opening and liberation of the amino group. Compounds of the formula I are starting substances for the preparation of renin inhibitors having anti-hypertensive activity.