baber/WOPTO huggingface dataset:
Patent DE-60333901-D1 (DE)
Inventor: COOKE JOHN
IPC: A61K31/00
Filed: 2003-02-04
Granted: 2010-10-07
Abstract: The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a nicotinic acetyl choline receptor antagonist. The methods are useful to treat conditions associated with or resulting from angiogenesis, particularly pathological angiogenesis. The invention further provides methods of treating a condition associated with or resulting from angiogenesis.
Patent DE-60334303-D1 (DE)
Inventor: HONJO TASUKU
IPC: C07K16/42
Filed: 2003-07-02
Granted: 2010-11-04
Abstract: Compositions for cancer or infection treatment via immunopotentiation caused by inhibition of immunosuppressive signal induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient, screening methods of the substrates for cancer or infection treatment, cell lines used for the screening methods, evaluation methods that selects the substrates for cancer treatment, and carcinoma cell transplanted mammals used for the evaluation methods.  The compositions of the present invention that inhibits the function of PD-1, PD-L1, or PD-L2 are useful for cancer or infection treatment,
Patent DE-68901335-D1 (DE)
Inventor: ROVIRA BADIA ANTONIO C O TIGSA
IPC: A01K39/01
Filed: 1989-12-13
Granted: 1992-05-27
Abstract: A fowl feeder of the type formed by a plate member with a spider members supported on a central tubular body member hanging vertically from the feed conveyor tube, which, unlike the known feeders in which the means for regulating the supply of feed to the plate member are complicated to handle, some requiring the raising or lowering of the conveyor tube and being, in general, easily thrown out of adjustment, the means comprised in the present feeder are constituted by two sleeve members, an upper one (21) from which the spider member (24) and the plate member (18) are suspended and which is capable of rotation on the tubular body member (1) while being supported on an upper step (21 min ) and opening the passage with lower lateral flared outlets (21 sec ) to lateral openings (20) of the tubular body member (1), and a lower one (12) which is vertically movable on said body member (1), the height thereof over the plate member being regulated by operation of a pawl (15) pivotably attached to the sleeve member (12) and engaging a rack means (11) provided on the tubular body (1).
Patent DE-68919068-D1 (DE)
Inventor: VENEMA GERHARDUS
IPC: C12N1/21
Filed: 1989-12-06
Granted: 1994-12-01
Abstract: This invention relates to genetically manipulated lactic acid bacteria capable of producing a lysozyme type enzyme. The invention further relates to the use of such bacteria in the manufacture of cheese, as well as to recombinant plasmids capable of being used for genetic manipulation.
Patent DE-68922204-D1 (DE)
Inventor: REUBEN BERTIE JOSEPH
IPC: C11D10/02
Filed: 1989-12-11
Granted: 1995-05-18
Abstract: The invention relates to aqueous stable liquid bleaching compositions comprising a sulfone peroxycarboxylic acid, an anionic surfactant, a non-ionic surfactant and optionally a salt stabilizer.
Patent DE-68923293-D1 (DE)
Inventor: ROSENTHAL ROBERT
IPC: G01N21/35
Filed: 1989-11-16
Granted: 1995-08-03
Abstract: A method and apparatus for determining whether a subsequent sample is substantially identical to an initial sample in a near infrared quantitative analysis instrument. An initial sample is measured for a plurality of characteristics which include the ambient temperature of the analysis instrument at the time of reading, the temperature of the sample itself, the optical energy level of the sample, the moisture content of the sample, and the percent protein of the sample. These characteristics are stored in a computer to provide a series of comparison criteria. A subsequent sample is then measured for the same characteristics as the initial sample and these characteristics are compared to the comparison criteria to determine if the subsequent sample is substantially identical to the previous sample. The subsequent sample is determined to be substantially identical to the initial sample for a given criterion if the subsequent sample's measurement for the corresponding characteristic is within a tolerance for that criterion. If the subsequent sample is judged to be substantially identical to the initial sample for all criteria, it is determined to be substantially identical to the initial sample.
Patent DE-68924440-D1 (DE)
Inventor: LEVANTO LAURI
IPC: G09F9/302
Filed: 1989-03-25
Granted: 1995-11-09
Abstract: The invention relates to a matrix display for the display of alphanumeric characters, one of the elements of the basically 5x3 matrix being divided into two parts (P5a, P5b). The matrix can also be applied to a printer.
Patent DE-68925567-D1 (DE)
Inventor: BARTSCH KLAUS E
IPC: A46B5/00
Filed: 1989-11-09
Granted: 1996-03-14
Abstract: The invention relates to a toothbrush with a deflecting part (4) which has a deflection profile and is positioned between brush head (1) and stem (5) for deflecting the brush head (1) when a certain contact pressure is reached. According to the invention the deflecting part (4) is a link (7), similar to a leaf spring, which connects the brush head (1) to the stem (5) and is covered at least on its front and back by a jacket (8) made of an elastomer. The elastomer is a natural or synthetic rubber, such as styrene-butadiene rubber, butyl rubber, ethylene rubber, propylene rubber, silicone rubber, or an ethylene vinyl acetate copolymer or plasticized PVC.
Patent DE-68928455-D1 (DE)
Inventor: EAST GARY P
IPC: A61M1/00
Filed: 1989-03-13
Granted: 1998-01-08
Abstract: A surgically implantable shunt system (20), including a flow control valve (24) and an antechamber (22), is provided for controlling the release of entrapped body fluids. The flow control valve (24) includes a pair of molded plastic bases (42, 44) situated, respectively, adjacent to an inlet (74) and an outlet (76) of the valve (24), which bases (42, 44) are situated within a flexible encasement (46). Each base (42, 44) includes an outer housing (48, 56), a valve membrane carrier (50, 58) positioned within the housing (48, 56), and a flow control member (52, 60). The flow control members (52, 60) each include a rigid nail-like central support and a separate flexible resilient membrane (70) positioned on the central support. The first flow control member (52) is capable of selectively occluding the valve inlet (74), but is normally spaced from its base (42) to permit free fluid flow through the inlet (74). The second flow control member (60) is generally arch-shaped and resiliently biased to contact its respective base (44) generally along the outer edge of the membrane (70) in a manner permitting only controlled one-way flow through the valve (24). The antechamber (22) permits injection of medication into the shunt (20) between a proximal catheter and the distal flow control valve (24), and pumping of the medication in either direction. Additionally, a method for assembling the shunt system (20) in a quick and economical manner is provided, which utilizes tapered grommets (96) to anchor components in place prior to adhesively securing tubing (28, 30) to the flexible encasement (46).
Patent DE-68929291-D1 (DE)
Inventor: SHAIKH GHALEB MOHAMMAD YASSIN
IPC: F42D5/04
Filed: 1989-12-06
Granted: 2001-05-23
Abstract: A metal product for use in extinguishing fires and the prevention of explosions comprising an expanded metal net formed by longitudinally stretching a continuous sheet of metal foil (10) having discontinuous slits (11) in spaced apart lines parallel to each other but transverse to the longitudinal dimension of the sheet, the longitudinal edges (13) of the continuous sheet being intercepted by slits on the slit lines, the metal net being formed into the form of an ellipsoid (18). <IMAGE>   <IMAGE>
Patent DE-69005011-D1 (DE)
Inventor: LE GARS JACQUES
IPC: F21V19/04
Filed: 1990-04-11
Granted: 1994-01-20
Abstract: The invention concerns a device for illuminating a bundle of optical fibres whose ends are gathered into a sleeve (2). 
<??>The device is chiefly noteworthy in that it incorporates a device (6) which monitors the operation of each of the lamps (5), the latter device providing an alarm in the event of any deficiency in the corresponding lamp. 
<??>Application especially to display devices. 
<IMAGE>
Patent DE-69007547-D1 (DE)
Inventor: BORGMAN ROBERT J
IPC: A61K9/12
Filed: 1990-06-05
Granted: 1994-04-28
Abstract: A composition and method for treatment of bacterial vaginosis and/or trichomoniasis are disclosed. An afflicted vagina is treated with a therapeutically effective amount of a buffered metronidazole composition having a pH in the range of about 3 to about 4.25, preferably about 3.75 to about 4.25. A preferred such composition comprises metronidazole, a gelled hydrophobic and water-dispersible polymer, such as a polyacrylic acid polymer having a molecular weight in the range of about 1,250,000 to about 4,000,000 daltons, and an aqueous solvent for the metronidazole.
Patent DE-69015885-D1 (DE)
Inventor: ANDERSON PAUL CATES
IPC: A61P9/12
Filed: 1990-05-31
Granted: 1995-02-23
Abstract: Disclosed herein are peptide derivatives which inhibit the activity of human immunodeficiency virus (HIV) protease. The peptide derivatives can be represented by general formula R<1>-R<2>-Y-R<3>-R<4> wherein R<1> is an optionally substituted 3-(1,2,3,4-tetrahydroisoquinolyl)carbonyl residue, R<2> and R<3> are amino acid or analogous amino acid residues (R<3> may optionally be absent), Y is a non-peptide linking unit, e.g. statyl, and R<4> is [-NR<1><7>CH(R<1><8>)C(O)]p-Z wherein R<1><7> is hydrogen or lower alkyl, R<1><8> is an amino acid or analogous amino acid side chain, p is zero or 1 and Z is a terminal group (e.g. hydroxy or amino), or R<4> is -NR<1><7>CR<1><8>(R<2><1>)CH2OH wherein R<1><7> and R<1><8> are as noted hereinabove and R<2><1> is hydrogen, lower alkyl or hydroxy(lower)alkyl. The derivatives also inhibit renin activity. Accordingly, the derivatives can be used for combating HIV infections or for treating hypertension or congestive heart failure.
Patent DE-69017916-D1 (DE)
Inventor: CROFT ALAN
IPC: C09C1/42
Filed: 1990-10-09
Granted: 1995-04-27
Abstract: The filtration rate and viscosity of a clay slurry is improved by the addition of a polyalkylene polyamine and, optionally, a latex. The additive is particularly useful in clay beneficiation.
Patent DE-69019366-D1 (DE)
Inventor: MARTIN FRANCIS
IPC: A61K38/095
Filed: 1990-10-19
Granted: 1995-06-14
Abstract: A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50  mu g agent/ mu mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Patent DE-69031114-D1 (DE)
Inventor: LIN FONG-JEI
IPC: G11C11/06
Filed: 1990-05-22
Granted: 1997-08-28
Abstract: A thin film magnetic core array has a large number of individual thin film core memory elements arranged on a substrate with X, Y, Z and SENSE conductor leads reeving through the core elements between contact pads arranged about the periphery of the array. Each thin film magnetic memory element includes a bottom pole, a top pole forming a closed magnetic path with the top pole, the structure surrounding the leads passing through the core, and insulation material for electrically insulating the leads from each other and from the pole pieces. The SENSE lead from the array is coupled to a miniature thin film transformer which amplifies the signals read from the individual core elements. The transformer has a bottom pole, a top pole forming a closed magnetic path with the bottom pole, including a central leg extending between the top and bottom poles, and a pair of electrically conductive coils mutually spaced in the region between the top and bottom poles. The array can be used independently of the transformer and vice versa; or the array and the transformer can be combined as a unit. Several arrays can be stacked to form a three dimensional memory unit. Both the array and the transformer are fabricated using integrated circuit fabrication techniques. <IMAGE>
Patent DE-69032112-D1 (DE)
Inventor: FISHER SUSAN
IPC: C12P21/08
Filed: 1990-07-30
Granted: 1998-04-16
Abstract: A relatively noninvasive procedure which allows prenatal diagnosis during early pregnancy utilizes anticytotrophoblast monoclonal antibodies. This procedure allows the detection of, and isolation of these cells from maternal blood samples. A screening procedure has been developed for hybridomas which produce monoclonal antibodies which are specific in that they interact with cytotrophoblasts, and not with other peripheral blood components.
Patent DE-69108258-D1 (DE)
Inventor: GARLICK ROBERT
IPC: C07K14/805
Filed: 1991-10-03
Granted: 1995-04-20
Abstract: An imidoester, cross-linked hemoglobin composition useful in the transport of oxygen to living cells and being essentially free of any impurities, a P50 of at least 13 mm Hg and predominantly in tetramer form. Preferably, the cross-linked hemoglobin composition has a predominant molecular weight of at least 64,000. The purified and cross-linked hemoglobin has improved cross-link stability to autoxidation and can be used as a blood substitute for mammals or as an oxygen transport fluid.
Patent DE-69113204-D1 (DE)
Inventor: SOOFI MADJID
IPC: B22D11/119
Filed: 1991-10-01
Granted: 1995-10-26
Abstract: Molten steel in tundishes can be contacted with high surface area ceramic shapes which remove the alumina and other impurities contained in steel. Certain ceramic shapes, in particular tundish baffles, having a large surface area which acts as alumina traps for molten steel contained in tundishes are also disclosed. <IMAGE>
Patent DE-69119225-D1 (DE)
Inventor: TUCKER WILLIAM
IPC: B43K21/22
Filed: 1991-02-06
Granted: 1996-06-05
Abstract: A mechanical lead pencil having the capability of feeding different diameter leads. A first collet (21) is disposed in the pencil barrel (12) for feeding the lead (20) and a second collet (25) is located at the barrel open end for retaining the lead (20) during use of the pencil. An elastomeric disc (35) is provided between the two collets (21, 25), having a variable diameter opening (38) at the center thereof for frictionally engaging the lead (20) and preventing its release when the two collets (21, 25) are in the open position.
Patent DE-69124812-D1 (DE)
Inventor: CHEN CHUAN-JU
IPC: C08K5/11
Filed: 1991-01-21
Granted: 1997-04-10
Abstract: Weatherable thermoplastic polymeric compositions are formed by blending weatherable grafted rubber composition with an aliphatic diester selected from the group consisting of dialkoxyalkoxyalkyl diesters and dialkoxydialkoxyalkyl diesters of aliphatic dicarboxylic acids containing 4 to 8 carbon atoms and 0-2% by weight based on the weight of the polyblend of a silicone fluid.
Patent DE-69126261-D1 (DE)
Inventor: GEPHARDT DOUGLAS D
IPC: G06F13/36
Filed: 1991-07-23
Granted: 1997-07-03
Abstract: The invention is an apparatus for use with a computing device for generating a substitute acknowledgement to a first input signal when the computing device is in an operational hiatus. The apparatus comprises a logical processing circuit for indicating presence of the first input signal depending upon the state of a second input signal, and a logical circuit for producing an output signal which is representative of a selection of one of the plurality of logical inputs. The selection of logical inputs is determined by the state of the second input signal. The first input signal is a hold request signal and comprises a first logical input to the logical processing circuit. A second logical input is a hold acknowledgement signal which is generated by the computing device in response to the presence of the first input signal when the computing device is not in an operational hiatus. <IMAGE>
Patent DE-69128793-D1 (DE)
Inventor: JAERVINEN PEKKA
IPC: B62B5/00
Filed: 1991-07-01
Granted: 1998-02-26
Abstract: A lifting device (1) for moving of a load (12) on one plane, changing of the moving plane and continuation of the moving on the second plane. The lifting device (19) comprises a body (2), a thereto supported, as to its vertical position by means of a lifting mechanism (4) guided sliding carrier (3) with forks (14), optional moving wheels (5), wheeled supporting arms (9), which while moving from one plane onto another can, guided by a slide element (10) connected to the body (2), be pulled substantially to the side of the body (2) that is opposite the load (12).
Patent DE-69131897-D1 (DE)
Inventor: GUTMAN JOSE
IPC: G06F13/00
Filed: 1991-10-07
Granted: 2000-02-10
Abstract: An electronic wallet (100) is capable of storing at least one of a financial information and a balance. Additionally, the electronic wallet (100) is capable of selective call receiving (200) a wireless message including financial information relating to a balance and updating the balance in response to the wireless message. <IMAGE>
Patent DE-69201316-D1 (DE)
Inventor: SANI MOHAMMAD NAJAFI
IPC: B23B27/14
Filed: 1992-02-28
Granted: 1995-03-16
Abstract: A method of producing a composite cutting insert for a twist drill includes the steps of cutting an intermediate blank (16) from a composite diamond compact (10). The intermediate blank comprises a relatively broad tungsten carbide strip (20) with a relatively narrow polycrystalline diamond strip (18) at one edge. First and second cutting insert halves (22.1, 22.2) are cut from the intermediate blank, each cutting insert half defining a cutting edge (26, 28) of the diamond material. The cutting insert halves are arranged back-to-back to form a composite cutting insert (24), with the cutting edges on opposite sides of a central plane (A-A). The cutting edges are arranged to define a chevron shaped composite cutting edge. The cutting insert halves are preferably brazed together to form a unitary cutting insert. The invention extends to a method of producing a twist drill including the steps of forming a slot-shaped seat (30) diametrally in the end of a twist drill body, and brazing the composite cutting insert into the seat. <IMAGE>
Patent DE-69203752-D1 (DE)
Inventor: VAN HAASTRECHT GIJSBERTUS CORN
IPC: C25D21/18
Filed: 1992-02-10
Granted: 1995-09-07
Abstract: A steel strip (1) is electrolytically coated with a metal layer at least partly of zinc in an electrochemical cell having an insoluble anode (4), wherein the strip acts as cathode. The electrolyte in the cell contains chloride ions and has high conductivity, reducing the voltage required. To avoid production of chlorine gas, hydrogen in the form of a hydrogen gas or gas containing hydrogen is supplied to the anode (4). The anode (4) is selected so that the anode reaction:    H2 -> 2H<+> + 2e<->   (V> takes place, this reaction (V) predominating at the anode over the reaction:    2Cl<-> -> Cl2  &uarr&  + 2e<->   (IV). <IMAGE>
Patent DE-69204010-D1 (DE)
Inventor: CLEMENCE MICHEL
IPC: H01R25/16
Filed: 1992-10-13
Granted: 1995-09-14
Abstract: Modular ducting element for distributing electrical power, composed of a box section in which are arranged busbars (3) for distributing electrical power, these being laterally accessible through distribution openings of the box section. 
<??>The box section includes two beams (8, 9) on either side of which are fixed two profiled strips (7), having a trough-shaped cross-section, the respective longitudinal edges (7B) of which are each elastically inserted into a longitudinal groove (10) of a beam, these profiled strips defining, between them and together with the beams, a longitudinal cavity in which the busbars (3) are fixed by means of blocks (6). A wedge (19) is forcibly inserted between one beam (9) and one end of a fixing block which is fixed against the other beam (8) by means of its other end in order to put the profiled strips under tension. 
<IMAGE>
Patent DE-69204555-D1 (DE)
Inventor: VAN VROENHOVEN PETRUS ADRIANUS
IPC: H04R25/02
Filed: 1992-06-02
Granted: 1995-10-12
Abstract: An in-the-ear canal hearing aid comprises a microphone (1), an amplifier (2), an electromechanical transducer (3), for example in the form of a telephone, and an infrared detector (15). The hearing aid further includes an extraction means (12) for extracting the hearing aid from the ear canal. The extraction means (13) is in the form of an optical conductor for conducting infrared radiation. One end (20) of the conductor (13) is mechanically attached to the hearing aid housing (4,6) in a place so that the end (20) of the conductor (13) is optically coupled to the detector (15). As a result, the extraction means (12) has as its second function conducting the infrared radiation to the detector of the hearing aid.   <IMAGE>
Patent DE-69205192-D1 (DE)
Inventor: AUDRY FRANCIS
IPC: A23L33/00
Filed: 1992-03-12
Granted: 1995-11-09
Abstract: The subject of the invention is liquid compositions comprising a carbohydrate fraction, a lipid fraction and a protein fraction, characterised in that the carbohydrate fraction contains at least the following two types of glucides (carbohydrates): 
 
  - glucose polymers, 
  - slow absorption glucides (carbohydrates), 
 the application of these compositions to the preparation of foods or of food supplements corresponding to specific nutritional requirements, their use as medicaments, and methods of dietary treatment using compositions.
Patent DE-69205298-D1 (DE)
Inventor: ALFARO CARCAR ALFREDO JOSE
IPC: A47C9/02
Filed: 1992-01-23
Granted: 1995-11-16
Abstract: The present invention relates to a bench for ground level low surfaced work comprising a substantially J-shaped profiled frame (1), which is provided at its ends respectively with a transversal knee (2) and seat supporting panel (3) provided with foam material or the like. The knee supporting panel (2) is hingedly connected to the frame (1) by hinge means (5). The bench comprises moreover belts (8, 9, 13) adapted to fix the user's knees, feet and body to the bench. The bench according to the invention allows to reduce or avoid physical pains when performing work at ground level. <IMAGE>
Patent DE-69210292-D1 (DE)
Inventor: EVANS ROBERT W
IPC: E21B31/113
Filed: 1992-02-07
Granted: 1996-06-05
Abstract: A double acting hydraulic drilling jar 1 includes a mandrel 2 arranged in a housing 3 for sliding longitudinal movement. A hammer 69 is positioned on the mandrel 2 and interacts with anvil surfaces 64, 66 in the housing 3 to deliver both upward and downward jarring forces to a drill string. A hydraulic valve arrangement permits the storage of large amounts of static force before releasing the hammer 69 to strike the anvil surfaces with great force. The hydraulic valve arrangement includes a tripping valve 95 positioned to be actuated by a first pair of engaging surfaces in response to downward movement of the mandrel 2 in the housing 3 and a second pair of engaging surfaces in response to upward movement of the mandrel 2 in the housing 3. Thus, independent control over the upward and downward jarring action is achieved.