baber/WOPTO huggingface dataset:
Patent CA-2169764-A1 (CA)
Title: Dampening of an immunodominant epitope of an antigen for use in plant, animal and human vaccines and immunotherapies
Inventor: GARRITY ROBERT R
IPC: C12P21/02
Filed: 1994-08-19
Abstract: The present invention provides a vaccine that can be administered to a mammal to cause immunoprotection in the mammal against a pathogenic organism that has an immunodominant epitope. The vaccine includes a modified form of the antigen in which the immunodominant epitope is located. In this modified form, the immunodominant epitope is immunodampened by any of a number of techniques. Examples of immunodampening techniques include addition of N-linked glycosylation sites, change of the net charge of the epitope, and substitution with a tolerated sequence. The vaccine also includes a pharmacologically acceptable carrier.
Patent CA-2170278-A1 (CA)
Inventor: CHAHWALA SURESH BABUBHAI
IPC: A61P15/00
Filed: 1994-08-10
Abstract: PCT No. PCT/EP94/02697 Sec. 371 Date Feb. 21, 1996 Sec. 102(e) Date Feb. 21, 1996 PCT Filed Aug. 10, 1994 PCT Pub. No. WO95/05822 PCT Pub. Date Mar. 2, 1995The R(+) isomer of amlodipine is a potent inhibitor of smooth muscle cell migration despite its lack of calcium channel-blocking activity. It is useful for treating atherosclerosis, re-stenosis after angioplasty and endometriosis.
Patent CA-2172217-A1 (CA)
Title: Agent for subcutaneous administration of protein c
Inventor: EIBL JOHANN
IPC: C07K19/00
Filed: 1996-03-20
Abstract: The invention relates to a pharmaceutical agent which is suitable for subcutaneous injection of protein C, wherein it comprises protein C and a pharmaceutically acceptable carrier.
Patent CA-2173380-A1 (CA)
Title: Power steering fluid reservoir
Inventor: MANCELL MICHAEL G
IPC: B62D5/06
Filed: 1996-04-03
Abstract: This invention relates to an improved reservoir for power steering fluid which is particularly suitable for use on large vehicles, such as trucks. The improved reservoir of this invention comprises a well to contain a surplus of power steering fluid. The well has an inlet to permit the introduction of fluid from a power steering mechanism into the well, and an outlet to permit the fluid to flow out of the well to the power steering mechanism. The well also has a filter attached over the inlet. The filter comprises a container having a lower chamber, a side chamber, a filter medium and a relief valve. Fluid received in the lower chamber from the inlet pipe flows to the side chamber and through the filter medium from the outside surface to the inside surface, and then out through a centre orifice to the well. Fluid at or above a predetermined pressure flows through the pressure relief valve and out through the centre orifice to the well.
Patent CA-2173941-A1 (CA)
Title: Method and apparatus for combining a tensioned elastic member with a moving substrate web
Inventor: BALL WALTER KENNETH
IPC: B32B37/14
Filed: 1994-09-29
Abstract: A method and apparatus for stretching an elastic member in cross machine direction and combining the elastic member, while held in tension, with a moving substrate web. A web of unstretched material, having elasticity across the direction of metering, is fed onto a first rotating drum at a speed slower than the surface speed of the drum. A cutter roll severs a portion of the unstretched material from its leading edge. Vacuum grippers in a drum slot beneath the elastic member support the ends of the member when it is cut from the web. Sealing dies are mounted to the surface of the vacuum grippers below the ends of the elastic member. As the first drum rotates further, the vacuum grippers are cammed axially outward within the slot to stretch the elastic member. Meanwhile, a substrate web is metered onto a second drum which rotates at the same surface speed as the first drum. The second drum rotates against the first drum but in the opposite direction. When the stretched elastic member reaches the nip point between drums, the sealing dies compression bond the ends of the stretched elastic member to the substrate web, using the second drum surface as an anvil surface. Vacuum applied to the second drum maintains the substrate web flat after the stretched elastic member is bonded and released by the vacuum grippers. A secondary sealing operation secures the stretched elastic member to the substrate web in locations other than the ends of the member before the elastic member and substrate web are allowed to contract.
Patent CA-2174348-A1 (CA)
Title: Methodologies for extracting and using muira puama
Inventor: CHERKSEY BRUCE D
IPC: A23K10/32
Filed: 1994-10-18
Abstract: A method. and related compositions, for reducing body fat percentage, increasing lean muscle mass, lowering cholesterol levels, and/or increasing HDL levels or decreasing LDL levels in individuals. The method consists of the ingestion of an extract derived from muira puama root, bark or other wood material. A method of preparing the muira puama extract into an easily ingestible and manipulatable solid form, and pharmaceutical compositions for use by mammalian subjects, are also disclosed.
Patent CA-2174928-A1 (CA)
Title: Compositions that specifically bind to colorectal cancer cells and methods of using the same
Inventor: WALDMAN SCOTT A
IPC: A61K47/48
Filed: 1994-10-26
Abstract: Conjugated compounds which comprise an ST receptor binding moiety and a radiostable active moiety are disclosed. Pharmaceutical compositions comprising conjugated compound which comprises an ST receptor binding moiety and a radiostable active moiety or an ST receptor binding moiety and a radioactive active moiety are disclosed. Methods of treating an individual suspected of suffering from metastasized colorectal cancer are disclosed. Methods of radioimaging metastasized colorectal cancer cells are disclosed. In vitro methods, kits and reagents are disclosed for determining whether or not an individual has metastasized colorectal cancer cells, for determining whether tumor cells are colorectal in origin and for analyzing tissue samples from the colon tissue to evaluate the extent of metastasis of colorectal tumor cells.
Patent CA-2176399-A1 (CA)
Title: Double-based lamp and socket therefor, and lamp base construction
Inventor: GREILER WOLFGANG
IPC: H01R33/02
Filed: 1996-05-09
Abstract: To insure that lamps which have a non-rotation symmetrical feature or structure with respect to aligned bases (e.g., a tipped-off exhaust or pumping stub) are placed in a predetermined preferred operating position when inserted into socket terminals (2a, 2b), the lamp bases are formed with stepped surface abnormalities (10a, 10b), for example, in the form of recesses or projections from a terminal engagement surface (8a, 8b) extending perpendicularly to the lamp axis (A-A); socket springs (2a, 2b) have matching surface abnormalities which interengage with the surface abnormality on the base, for example by being formed with ridges, or depressions. The lamp thus can be inserted in such bases only if the respective surface abnormalities on the lamp bases and in the socket terminals can engage. The lamp, however, can be used also with socket terminals which do not have such interengagement surface abnormalities, so that the lamps are universally usable with specific location-determining sockets, or with sockets where the position of the lamp must be determined by a user:
Patent CA-2177250-A1 (CA)
Title: Surface treatment nozzle and method and device for surface treatment using such a nozzle
Inventor: MOLLARD THIERRY
IPC: B05B1/04
Filed: 1994-11-25
Abstract: Surface treatment nozzle for projecting solid particles carried along in a pressurized gas stream. Said nozzle comprises a channel having, in the direction of flow of the solid particles, firstly a converging section (6), then a diverging section (7) which opens from the nozzle as an outlet slot (4) and whose cross section is flattened parallel to said outlet slot, at least in the vicinity thereof. The channel cross section varies gradually along its entire length; the converging section (6) comprises an upstream end (5) flattened parallel to the outlet slot, the diverging section having two lateral portions of enlarged cross section (41).
Patent CA-2180809-A1 (CA)
Title: A process for low temperature heat sealing of polyethylene
Inventor: GILLESPIE BRUCE ALEXANDER
IPC: B29C65/00
Filed: 1996-07-09
Abstract: A process of producing a heat sealed extrusion coated polyethylene article is disclosed. This process entails heat sealing, at a temperature below 95°C, two opposing extrusion coated polyethylene laminate surf aces thereby welding the surfaces to effect a heat seal. The polyethylene has a narrow molecular weight distribution, a low melt index, a low swell ratio, and a polydispersity index below 5.
Patent CA-2181110-A1 (CA)
Inventor: REMINGTON JAMES A
IPC: E01B7/10
Filed: 1996-07-12
Abstract: A railroad trackwork railbound frog assembly having a toe point element is provided with a pair of spaced-apart wing rail elements each having a notch recess feature, a pair of reversible and interchangeable spaced-apart wing rail insert elements, usually fabricated of a manganese alloy steel or a high-strength, low-alloy steel material that is harder than the  material  from  which the  wing  rail  elements  are manufactured, installed in abutting relation to the wing rail element notch  recesses,  spacer  blocks  that  maintain  the separations between the toe point, wing rail, and wing rail insert elements, and bolt-type fastener devices joining the elements of the frog assembly into a unitary structure.
Patent CA-2181300-A1 (CA)
Inventor: HANSON MARVIN L
IPC: B21D28/06
Filed: 1996-07-16
Abstract: A method is provided for producing a hitch receiver from a blank of construction material in a way that significantly reduces the waste material that is generated.  The method includes the step of cutting a side frame bracket with at least one section of reduced profile from the blank of construction material.  In addition, the method includes the step of cutting other component parts for the hitch receiver from an expanse of the blank of construction material preserved by the reduced profile section of the side frame bracket.  The method also includes the step of reducing the scrap material generated by the cutting of the blank of construction material to less than 5.1 % of the total surface area and weight of the blank.
Patent CA-2182459-A1 (CA)
Inventor: MURAMATSU TATEO
IPC: B62D55/12
Filed: 1996-07-31
Abstract: A positive drive endless rubber track system for the undercarriage of a vehicle, the rubber track including spaced guide lugs projecting inwardly therefrom, the undercarriage including a drive wheel having spaced sprocket pins thereon, idler wheels, and tension adapting wheels around which the endless rubber track is guided and driven by the driving wheel, the drive wheel being attached to the vehicle and having an up-ratio in the range of about 0.5% to about 4.0%.
Patent CA-2186738-A1 (CA)
Inventor: FORSE R ARMOUR
IPC: A23L29/00
Filed: 1995-03-29
Abstract: Compositions entérales contenant de la saponine pour le traitement des infections et inflammations, qui sont particulièrement utiles combinées avec des huiles riches en acides gras polyinsaturés .omega.3, telles que des huiles de poisson et de l'huile de lin, présentant également des effets bénéfiques avec des huiles riches en .omega.6, telles que de l'huile de bourrache, de l'huile de pépins de cassis, de l'huile de colza canola et de l'huile de colza. Lesdites compositions peuvent également contenir un lignane de la famille des sésamines.
Patent CA-2188089-A1 (CA)
Inventor: READ CLIFFORD D
IPC: H04M1/02
Filed: 1996-10-17
Abstract: A telephone unit which may be a handset has a display screen.  A cover is movable so as to cover or uncover the display screen and the cover carries representations of dialing positions arranged in a keyboard format.  The cover is flexible and pressure applied to it at any selected dialing position causes a transmission of the pressure to a corresponding screen position, with the cover over the screen, to provide a dialing signal.  With the cover removed, the screen has at least one other function.
Patent CA-2189030-A1 (CA)
Inventor: VURAL GUELERTAN
IPC: E01C23/06
Filed: 1996-02-27
Abstract: L'invention concerne un véhicule utilisé pour la réparation des revêtements endommagés de chaussées par égalisation au moyen d'un matériau de remplissage. Le véhicule présenté comprend, de façon connue, une unité de chauffage et de scarification (3, 4, 5), un dispositif de distribution (6) qui distribue le matériau de remplissage, un outil de compactage (7) à fonctionnement dynamique, utilisé pour compacter le matériau de la chaussée scarifiée et le matériau de remplissage ajouté, qui est situé derrière le dispositif de distribution à un niveau supérieur à celui de la partie non endommagée de la chaussée, et un outil égaliseur, placé derrière l'outil de compactage (7), qui, pendant son fonctionnement, exécute un mouvement de va-et-vient horizontal, transversalement par rapport au sens de déplacement du véhicule, et est utilisé pour enlever le matériau de remplissage en excès derrière l'outil de compactage. Selon l'invention, l'outil égaliseur (8) peut être levé ou abaissé, de façon commandée, indépendamment du dispositif de distribution (6) et de l'outil de compactage (7), et il est monté sur le dispositif de distribution (6). Le véhicule selon l'invention est également pourvu d'un autre outil de compactage (22) à fonctionnement dynamique, placé derrière l'outil égaliseur (8) et à proximité de celui-ci. Avec le véhicule proposé, il est possible de garantir qu'une petite couche de matériau en excès reste toujours derrière l'outil égaliseur (8), au-dessus du niveau de la partie non endommagée de la chaussée ou au-dessus du niveau désiré d'un nouveau revêtement, cette couche de matériau en excès pouvant être définie de façon qu'elle soit assez grande pour fermer les vides restant derrière l'outil égaliseur pendant le compactage complémentaire effectué par l'outil de compactage additionnel.
Patent CA-2191375-A1 (CA)
Title: System and method for capacity management in multi-service networks
Inventor: MAXEMCHUK NICHOLAS FRANK
IPC: H04L12/56
Filed: 1996-11-27
Abstract: A methodology for allocation of transmission capacity in communications networks is provided wherein a collection of constant rate channels is implemented between end points in the network. In that methodology, periodic sources are assigned channels of bandwidth corresponding to the transmission rate for each such source, and bursty sources are assigned to channels providing bandwidth corresponding to a minimum service guarantee for each such bursty source. Channel capacity assigned to periodic services which is not needed by such sources is then made available to bursty sources for accommodating capacity requirements of such bursty sources over and above the minimum service guarantee.
Patent CA-2197289-A1 (CA)
Inventor: BOSMA MARINUS A
IPC: E04G23/08
Filed: 1997-02-11
Abstract: A device for breaking concrete and similar frangible materials to reduce it to rubble includes a power plunger and an actuator plunger mounted within a casing.  The casing is carried on and operated by construction equipment such as a back hoe.  As the back hoe is operated to cock the power plunger by moving the actuator plunger toward the concrete surface, a trigger mechanism affixed to the actuator plunger lifts the power plunger and an associated latch member to load a coil spring associated with the power plunger and presses against the latch member.  As the coil is fully compressed, the trigger mechanism engages a trigger operating abutment and releases the latch member.  The coil spring then fires the power plunger against the concrete.          An improved trigger mechanism and latch member are provided with essentially spherical latching edge portions which compensate for misalignment of the power and actuator plungers due to wear of their bearings and the torsional effect of loading the coil spring, increasing the life of the parts and reducing the frequency of necessary repairs.        The arrangement and shape of the latching edges are such that further coil spring compression is avoided when the latch member is released.  In its preferred and simplist form, the trigger and latch members are produced from cast solid steel blocks welded to their respective plungers.
Patent CA-2198170-A1 (CA)
Inventor: VIS JEAN
IPC: B02C13/09
Filed: 1997-02-20
Abstract: The anvil (10) overall has the shape of a prism with one curved lateral surface  (16)  and two lateral surfaces (18)  (20) which have flanks (26)  (28) adjacent to the curved surface (16) and directed along the axis of curvature of this surface (16). These flanks (26)  (28) are moreover inclined with respect to a mid-plane of the anvil (10) passing through the axis of curvature of the surface (16). These anvils (10) are arranged alternately in one direction then the other in an anvil ring where they are held by an arch keystone effect to form a circle of anvils.
Patent CA-2199408-A1 (CA)
Title: Herpes simplex virus glycoprotein d variants
Inventor: COHEN GARY H
IPC: A61K38/00
Filed: 1996-07-03
Abstract: The present invention provides variant HSV-1 glycoprotein D and HSV-2 glycoprotein D molecules capable of preventing infection of cells by herpes simplex virus types 1 and/or 2. Also provided are novel purified and isolated polynucleotides encoding the variant gD  molecules. HSV gD-1 and gD-2 region IV variants or fragments thereof are specifically contemplated by the invention. The presently preferred variant molecule gD-1(.DELTA.290-299t) is the product of recombinant expression in Sf9 cells of a fusion protein including the signal peptide of honeybee melittin and Patton strain HSV-1 gD wherein (1) the Patton strain amino acid residues 290 through 299 of the mature gD-1 protein have been replaced with the amino acid residues arginine, lysine, isoleucine and phenylalanine, and (2) Patton strain amino acid residues 308 through 369 have been replaced with five histidine residues.  When expressed in Sf9 cells, cleavage of the melittin signal peptide results in the presence of aspartate and proline residues at the amino terminus of the variant molecule. The amino acid sequence of gD-1(.DELTA.290-299t) is set out in SEQ ID NO: 2 and the preferred DNA  sequence encoding gD-1(.DELTA.290-299t) is set out in SEQ ID NO:  1. Administration of gD variant molecules of the invention to mammalian subjects, especially humans, for the purpose of preventing HSV  infection and/or ameliorating pathological sequelae of HSV infection is specifically contemplated.
Patent CA-2201883-A1 (CA)
Title: Refrigerating machine oil composition
Inventor: KANEKO MASATO
IPC: C10M133/06
Filed: 1995-09-14
Abstract: A refrigerator oil composition prepared by blending a base oil comprising a mineral or synthetic oil with at least one member selected from the group consisting of metal salts of inorganic phosphoric acid (e.g. potassium phosphate), amine salts of inorganic phosphoric acid (e.g. octylamine salt of phosphoric acid), metal salts of organic phosphoric acid (e.g. dipotassium lauryl phosphate), amine salts of organic phosphoric acid (e.g. monooctylamine salt of dioleyl phosphate), metal salts of organic phosphonic acid (e.g. dipotassium oleylphosphonate), amine salts of organic phosphonic acid (e.g. octylamine salt of dilaurylphosphonic acid), metal salts of organic phosphorous acid (e.g. sodium dioleyl phosphite), and amine salts of organic phosphorous acid (e.g. oleylamine salt of dioleyl phosphite). The composition has an excellent lubricating performance, improves the lubricity of the interface between an aluminum material and a steel material, can inhibit seizure and wear, and is suitable as a lubricating oil for refrigerators using a hydrochlorofluorocarbon refrigerant which does not cause environmental pollution, such as R134a.
Patent CA-2206154-A1 (CA)
Inventor: GEREZ VALERIO
IPC: F01D25/16
Filed: 1997-05-13
Abstract: L'invention propose un procédé et un dispositif permettant de maintenir en fonctionnement un turbomoteur pour aéronef malgré l'apparition d'un balourd accidentel sur un rotor, provoqué par exemple par la rupture d'une aube de soufflante. Selon l'invention : - on maintient le rotor (1) par au moins un support de palier (17) présentant au moins deux niveaux de souplesse 35, 36), - on agrandit le jeu E entre des sommets (8) des aubes (7) et la paroi intérieure (9a) du carter (10), - on passe d'un niveau de raideur normal (35) du support de palier (17) à un niveau de raideur faible (36) après l'apparition d'un balourd supérieur à une valeur minimale prédéterminée, par la rupture d'éléments de liaison frangibles (30).
Patent CA-2208072-A1 (CA)
Title: Recombinant antigen for diagnosing rheumatoid arthritis
Inventor: PRAKASH RAMESH K
IPC: C12P21/08
Filed: 1995-12-15
Abstract: A method is described for diagnosing rheumatoid arthritis by providing a recombinant antigen (RAMA) and detecting rheumatoid arthritis-associated IgM antibodies against the RAMA antigen in patient sera. The RAMA antigen comprises SEQ ID NO:3 and peptides substantially homologous thereto. A purified and isolated DNA encoding the RAMA antigen and a transformed host containing the DNA are also disclosed.
Patent CA-2208461-A1 (CA)
Inventor: STEVANOVIC LJUBISA DRAGOLIJUB
IPC: H05B41/38
Filed: 1996-10-28
Abstract: A filament-heater power supply includes a combination forward and flyback power converter for supplying electronically variable, isolated voltages to dimmable discharge lamp filaments while supplying a fixed do output voltage to a ballast control circuit. Hence, only a single ballast power supply is needed. The control circuit controls the level of filament voltage to operate the lamp filaments at an optimum temperature, even during dimming operation, thereby substantially extending lamp life. The filament-heater power supply provides a high degree of isolation among filament voltages while regulating and tracking the voltage across each filament. The filament-heater power supply can preheat the filaments to aid lamp starting, thereby extending the useful life of the lamp, and is also structured to sense when a lamp is not present in a fixture so that high voltage starting pulses are not applied to the terminals of an empty fixture.
Patent CA-2210308-A1 (CA)
Title: Vented seal with rocking vent cover
Inventor: MORGAN WILLIAM K
IPC: B65D51/16
Filed: 1997-07-14
Abstract: A vent assembly for the top panel of a seal for a food container including a vent opening in the seal panel at least partially surrounded by an upwardly opening-recess with the vent opening and recess being below the upper surface of the seal panel. A vent cover, including a depending plug selectively receivable in the vent opening, is pivotally mounted by a hinge assembly which included a hinge pin on said cover received within spaced trunnion bores in the recess adjacent the vent opening. The trunnion bores are laterally enlarged relative to the pin diameter and of a generally oval configuration.
Patent CA-2212447-A1 (CA)
Title: Thin layer solvent extraction
Inventor: JOHNSON CONRAD B
IPC: C10G1/04
Filed: 1997-08-07
Abstract: A method for separating hydrocarbons from a soil, e.g. to separate bitumen from oil sands, involves mixing the soil thoroughly with water and a supply of buoyant beads having surfaces that are of oleophilic material and coated with a surface layer of hydrocarbon solvent. The beads, soil and water are agitated for a period during which hydrocarbons from the soil become adhered to the solvent coated beads. After the mixture has been allowed to settle the beads separate towards the top and are removed and treated with solvent to recover the adhered hydrocarbons therefrom. Suitable solvents are oil refinery products such as naphtha, kerosine, gasoline, varsol, toluene and diesel fuel.