baber/WOPTO huggingface dataset:
Patent ES-2007425-A6 (ES)
Title: Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof.
Inventor: IWATA KENNETH K
IPC: A61K35/44
Filed: 1987-10-19
Abstract: The invention provides a composition of matter designated tissue-derived growth inhibitor-1 (TGI-1) which comprises a protein which is a dimer composed of two polypeptides each having an apparent molecular weight of about 13,000 daltons and being joined to each other by disulfide bonds. TGI-1 has the property of inhibiting the growth of human tumor cells and of an established mink lung cell line (CCL 64) but not the growth of normal human foreskin fibroblasts and has an apparent molecular weight of about 26,000 daltons. The invention additionally provides a composition of matter designated tissue-derived growth inhibitor-2 (TGI-2) which is a protein which has the property of inhibiting the growth of human tumor cells and of an established mink lung cell line (CCL 64) but not the growth of normal human foreskin fibroblasts. TGI-2 has an apparent molecular weight of about 26,000 daltons and is a dimer composed of two polypeptides each of which has an apparent molecular weight of about 13,000 daltons and each is joined to the other by disulfide bonds under nonreducing conditions. This invention also provides a protein having tumor growth activity comprising the 112 amino acids shown in Figure 29 beginning with alanine at positon 1 and ending with serine at position 112. A nucleic acid molecule encoding the protein is also provided. A polypeptide designated CM-1 and a polypeptide recoverable from conditioned media of A431 cells are also disclosed.
Patent ES-2005753-A6 (ES)
Title: Immunologically active polypeptides useful for the preparation of antimalarial vaccines and of diagnostic kits for the detection of antisporozoite antibodies
Inventor: BERNARDI ADRIANO
IPC: A61K39/00
Filed: 1987-12-04
Abstract: Immunologically active polypeptides constituted, towards the N-terminated end, by an Asn-Val-Asp-Pro-Asn-Ala-Asn-Pro sequence repeated three times and, towards the C-terminated end, by at least three quadruplets with an Asn-Ala-Asn-Pro sequence, linked with each other by means of an amidic bond between the end proline of the first sequence, and the initial asparagine of the first quadruplet. Said polypeptides reproduce nearly exactly the sequential structure of the circumsporozoite protein of P. falciparum, and are useful for the preparation of antimalarial vaccines and of diagnostic kits for the detection of antisporozoite antibodies in clinical samples of malariated persons.
Patent ES-2007272-A6 (ES)
Title: Oil seal with antirotation ribs.
Inventor: BOYERS DOUGLAS B
IPC: F16J15/32
Filed: 1988-07-22
Abstract: A unitized oil seal is provided with axially extending and radially protruding elastomeric ribs for preventing rotation of one of the oil seal members about a shaft or within a bore. The ribs are designed to reduce installation forces and thereby reduce seal damage due to excessive deformation during installation.
Patent ES-2010356-A6 (ES)
Title: Stopping sleeve for shafts.
Inventor: HERWIG WOLFGANG
IPC: F16B21/18
Filed: 1988-09-07
Abstract: A stopping sleeve (1) for shafts is held in a specific position on a shaft (6) by means of a radially elastic stop ring (12). The stopping sleeve (1) has a longitudinal bore (4) with two peripheral grooves (7 and 11) of different diameters, between which is formed a funnel-shaped section (10). The stop ring (12) is set within the larger groove (11), so that the stopping sleeve (1) and ring (12) form a prefabricated structural unit (1, 12). The prefabricated structural unit (1, 12) can be easily and automatically slipped on the shaft (6), so that the stop ring (12) does not touch the shaft (6). The stop ring (12) is then held by an auxiliary tool (17) in its axial position with respect to a snap ring groove (16) of the shaft and pressed into the snap ring groove (16) when the stopping sleeve is further axially displaced, the initial section (10) applying a pressure on the stop ring (12) until in the mounting position the peripheral groove (7) of smaller diameter engages the stop ring (12).
Patent ES-2013010-A6 (ES)
Title: Machine for automatically rolling hides
Inventor: ADAM BONAY JUAN
IPC: A41H43/02
Filed: 1989-01-13
Abstract: Machine for automatically rolling hides. Characterised in that it comprises a feed device for flat packs of hides using a motorised conveyor belt system which is combined with a rolling head equipped with two motor-driven plates each bearing pairs of projecting rolling appendages each combined with guide systems transverse to the machine to permit transverse inward and outward movements for the purposes of completing the cycle of the rolling of a package of hides, releasing the same when rolling is complete. <IMAGE>
Patent ES-2011202-A6 (ES)
Title: Antiallergic compound for application to articles of costume jewellery
IPC: A44C27/00
Filed: 1989-05-12
Abstract: The invention relates to a compound which is capable in the liquid state of being applied to articles of costume jewellery or the like in such a way that, after drying, an antiallergic protective film is formed on the article, said compound comprising an acrylic resin and a solvent.
Patent ES-2019718-A6 (ES)
Title: Double magic cube
IPC: A63F9/12
Filed: 1989-07-04
Abstract: It consists of a pair of cubes with 26 movable dice, each one being visible, with a mechanism which makes it possible to transfer the relative movements from one to another precisely and symmetrically. Intended to facilitate the compression and objectivity of spatial movements, their symmetry and the mechanisms of transmission, which, in addition, can transfer inverse movements in order to widen the possibilities of resolution of the 52 dice. Applicable as an educational toy.
Patent FR-2165519-A6 (FR)
Title: Paper sizing - with soln of salt of copolymer of olefin, (meth) acrylic acid, and unsatd semiester, semiamide or alcohol
IPC: D21H17/43
Filed: 1972-12-13
Granted: 1973-08-03
Abstract: In the parent patent surface sizing of paper is effected by treating the paper with an aqs. soln. of a salt of a statistical copolymer of (I) 50-90wt.% 2-12C alpha-olefin, (II) 10-50wt.% (meth)acrylic acid, and (III) 0.1-30wt.% of another non-basic copolymerisable monomer. Now claimed is III as a semi-ester and/or semi-amide of a 3-5C monoolefinically unsatd. dicarboxylic acid and/or a monoolefinically unsatd. alcohol, and the copolymer has a K value of 20-45. Excellent sizing effect, good resistance to alkali, good compatibility with fillers are obtd.
Patent BE-1002631-A7 (BE)
Title: Warmwaterreservoir.
IPC: F24D3/08
Filed: 1988-12-08
Granted: 1991-04-16
Abstract: De reservoirruimte van een doorloopwarmwaterreservoir wordt door een geleidingswand (5), die zich over slechts een deel van de reservoirhoogte uitstrekt, onderverdeeld in een ringvormige, een verwarmende buisspiegel (2) bevattende buitenste ruimte (6) en een door de geleidingswand (5) omsloten centrale binnenruimte (7), van welks binnenste gebied de warmwater aftapleiding (8) uitgaat.
Patent BE-1009757-A7 (BE)
Title: Bandages wherein the shapes and colours are defined by the drawings that they represent
IPC: B44C1/00
Filed: 1995-11-21
Granted: 1997-08-05
Abstract: Bandages wherein the shapes and colours are defined by the drawings that they represent and which are not necessarily related and limited to the area on which they are applied or to the injuries they cover. These bandages may have all possible and imaginable shapes and descriptions, ranging from the colour representation of a comic book character to a black and white drawing which need only be coloured in. These bandages being original, various applications such as the vocal system (talking pins) or musical chimes may be applied thereto. These bandages, in addition to their medical qualities, will provide patients with a form of distraction and a little extra something that so often makes the difference.
Patent FR-2350765-A7 (FR)
Title: Steam disinfecting appts. for soil - has water tube boiler mounted on metal cloche
IPC: A01G11/00
Filed: 1976-05-03
Granted: 1977-12-02
Abstract: The apparatus for disinfecting soils with steam comprises a metal cloche (1) on which is mounted a steam-generating boiler (2), the steam being led from boiler (2) to cloche (1) by a tube. The steam boiler (2) comprises water tubes, and a demountable heating body (7) carrying a vertical oil or gas burner (10). The tube (17) extends through the interior of the boiler (2), and a second tube (171) extends externally of the boiler (2). The base (6) of the boiler (2) is fixed by bolts to the plate (3) forming the top wall of the cloche (1). The cloche top wall may be formed at least partly by the base (6).
Patent FR-2336048-A7 (FR)
Title: Valve for washing or dishwashing machine - with two balls opening and closing tube leading to drain pump
IPC: D06F39/08
Filed: 1976-12-02
Granted: 1977-07-15
Abstract: Valve for washing or dishwashing machine comprises a housing enclosing two balls and having a connecting tube for a pipe leading to a drain pump and a connecting tube for a pipe leading to a drainage outlet. In the inoperative position, the lower ball supports the total wt. of the upper ball which is located perpendicularly above it, closing the tube leading to the drain pump. In the operative position, it releases this tube and holds the upper ball against an inclined surface of the housing, in which position the centres of the two balls are laterally offset from each other. The valve has a powerful closure force, and functions reliably independently of the position of the tub and drainage outlet.
Patent FR-2345057-A7 (FR)
Title: Rubber nozzle for gripping hot articles - with asbestos coating on contact surfaces
IPC: C03B35/00
Filed: 1977-03-17
Granted: 1977-10-14
Abstract: Nozzle of conventional shape for gripping hot articles, e.g. of glass or similar material, is made of rubber or similar elastic material, with an asbestos coating, on (parts of) the surface which comes into contact with the article. Pref. the asbestos coating is in the form of a rim fitted over the nozzle. The contact surface is pref. protected by a ring of asbestos cloth clamped in the common gripping device. The asbestos coating may be fixed by vulcanisation during mfr. of the nozzle. The nozzle is elastic, and can withstand high temps. and breakage within a short period.
Patent FR-2405000-A7 (FR)
Title: Four-position foot operated switch esp. for dental equipment - has pedal consisting of domed surface carrying short rod which operates microswitch
IPC: A61C1/00
Filed: 1978-09-18
Granted: 1979-04-27
Abstract: The foot operated switch for the control of electrical instruments is esp. for dentists' equipment. The switch contains four separate microswitches (9) set in quadrature, the pedal (3) being depressed forward or backward etc. to close any one of the four. Minimum ankle movement is required since the pedal height remains constant throughout the movement. The pedal consists of a domed surface moving within a shaped cover (1) and carries on its underside a short rod (4) bearing on a block (5) which actually operates the microswitches by depression into a rubberised metal base plate (6).
Patent CU-20100041-A7 (CU)
Title: Nuevos herbicidas
Inventor: SMITH STEVE
IPC: A01N43/08
Filed: 2010-03-03
Abstract: Los compuestos de fórmula ESPACIO PARA LA FÓRMULA en donde los sustituyentes son como se define en la reivindicación 1, son adecuados para usar como herbicidas
Patent CU-20100262-A7 (CU)
Title: Compuestos orgánicos
Inventor: ZHANG ZAIHUI
IPC: A61K31/4439
Filed: 2010-12-27
Abstract: La presente invención proporciona derivados heterocíclicos que modulan la actividad de la estearoil-CoA-desaturasa (SCD). También se abarcan métodos para utilizar estos derivados con el fin de modular la actividad de la estearoil-CoA-desaturasa (SCD), y composiciones farmacéuticas que comprenden tales derivados.
Patent CU-20110027-A7 (CU)
Title: Peptidomiméticos de smac útiles como inhibidores de proteínas de apoptosis (iap)
Inventor: YANG FAN
IPC: A61K31/427
Filed: 2011-02-02
Abstract: La presente invención se refiere a un compuesto de la fórmula (I); o sales farmacéuticamente aceptables del mismo útiles para el tratamiento de enfermedades proliferativas, tales como cáncer, en mamíferos. ESPACIO PARA LA FÓRMULA
Patent CU-20150020-A7 (CU)
Title: Composición farmacéutica recubierta que contiene regorafenib
Inventor: SKRABS DR SUSANNE
IPC: A61K9/00
Filed: 2015-03-04
Abstract: La presente invención se refiere a una composición farmacéutica recubierta que contiene regorafenib, un hidrato, solvato, metabolito o sal farmacéuticamente aceptable del mismo, o un polimorfo del mismo y su procedimiento de preparación y su uso para tratar trastornos.
Patent DD-300045-A7 (DD)
Title: Saugzuganlage für Schornsteine
Inventor: FLOR DIETER
IPC: F23L17/02
Filed: 1990-02-06
Abstract: Die Erfindung betrifft eine Saugzuganlage fuer Schornsteine mit Injektorduese zur Zugerhoehung in Schornsteinen und auf Schornsteinkoepfen fuer Heizungs- und Kesselanlagen, deren natuerlicher Zug fuer die ordentliche Verbrennung der eingesetzten Energietraeger nicht ausreicht. Durch diese Duese werden die Nachteile der bisher bekannten technischen Loesungen, wie die Behinderung beim Fegen des Schornsteines sowie die schwer durchfuehrbare Reparatur und Wartung beseitigt und dabei gleichzeitig ein wesentlich geringerer Energieaufwand erreicht. Die Loesung resultiert aus einer kompakten, stroemungstechnisch guenstigen und im wesentlichen quaderfoermigen Injektorduese mit mehreren inneren Leitblechen. Mit dieser Erfindung werden die Voraussetzungen geschaffen, an fuer die Verbrennung von Braunkohlenbriketts vorgesehenen Heizungsanlagen ohne groeszere Investitionen selbst Foerderkohle (Rbk 5 und 6) energieoekonomisch verbrennen zu koennen.{Injektorduese; Schornsteinzugerhoehung; Energietraegersubstitution; Niederdruckkessel; indirekter Saugzug; Schornsteineinbauten; Rauchfoerderer; Luftleitelemente; Ventilatorgeblaese}
Patent WO-0158493-A8 (WO)
Title: Conjugates of follicle stimulating hormones
Inventor: SCHAMBYE HANS THALSGAARD
IPC: C07K14/59
Filed: 2001-02-09
Abstract: The invention relates to heterodimeric polypeptide conjugates exhibiting FSH activity, comprising a dimeric polypeptide comprising an FSH-α subunit and an FSH-β subunit, wherein at least one of the FSH-α and FSH-β subunits differs from the corresponding wildtype subunit in that at least one amino acid residue acid residue comprising an attachment group for a non-polypeptide moiety has been introduced or removed, and having at least one non-polypeptide moiety bound to an attachment group of at least one of said subunits. Preferably, at least one attachment group, e.g. an N- or O-glycosylation site or an attachment site for a polymer molecule such as polyethylene glycol, has been introduced, e.g. at an N-terminal. The polypeptide conjugates exhibit improved properties, in particular an increased half-life, compared to human FSH.
Patent WO-0238561-A8 (WO)
Title: Derives d'indolylmaleimide utilises en tant qu'inhibiteurs de proteine kinase c
Inventor: ALBERT RAINER
IPC: A61K31/551
Filed: 2001-11-05
Abstract: L'invention porte sur des dérivés d'indolylmaléimide contenant un résidu phényle, naphtyle, tétrahydronaphtyle, quinazolinyle, quinolyle, isoquinolyle pyrimidinyle substitués, et présentant des propriétés pharmaceutiques intéressantes, par exemple dans le traitement et/ou la prophylaxie des maladies ou troubles inflammatoires chroniques ou aigus induits par les lymphocytes T, des maladies auto-immunes, des rejets de greffons ou des cancers.
Patent WO-0248109-A8 (WO)
Title: Composes a base de n-alkoxy-4,4-dioxy-polyalkyl-piperidine presentant des groupes glycidyle ou alkylcarbonyle qui servent d'initiateurs fonctionnels de polymerisation radicalaire controlee
Inventor: FUSO FRANCESCO
IPC: C08F4/00
Filed: 2001-11-12
Abstract: La présente invention concerne des composés sélectionnés, à base de N-alkoxy-4,4-dioxy-polaylkyl-pipéridine à fonction glycidyle ou carbonyle, qui forment une chaîne ouverte ou une structure de cétal cyclique. Cette invention concerne également une composition polymérisable comprenant a) au moins un monomère éthyléniquement insaturé et b) un composé initiateur à base de nitroxyde de N-alkoxy-4,4-dioxy-polaylkyl-pipéridine à fonction glycidyle ou carbonyle. En outre, cette invention concerne un procédé pour polymériser des monomères éthyléniquement insaturés, ainsi que l'utilisation d'initiateurs à base de nitroxyde de N-alkoxy-4,4-dioxy-polaylkyl-pipéridine à fonction glycidyle ou carbonyle dans le cadre d'une polymérisation radicalaire.
Patent WO-02081521-A8 (WO)
Title: Osteoprotegerine dans le lait
Inventor: VIDAL KARINE
IPC: A23K1/16
Filed: 2002-03-15
Abstract: L'invention concerne l'ostéoprotégérine qu'il est possible d'obtenir à partir de sources laitières, notamment à partir de lait d'humain et de bovin. Elle concerne aussi l'utilisation de ce composé pour la confection de préparation ingérable et/ou de composition pharmaceutique, et en particulier l'utilisation d'une telle préparation/composition afin de prévenir ou de traiter des troubles associés au métabolisme osseux et à la fonction immunitaire.
Patent WO-02082860-A8 (WO)
Title: Procede et systeme pour diffuser selectivement des informations dans un espace, et equipements mis en oeuvre dans ce systeme
Inventor: GILBERT JEROME
IPC: H04R27/00
Filed: 2002-04-04
Abstract: Procédé pour diffuser sélectivement des informations dans un espace à des personnes pourvues d'un terminal de réception portable, comprenant une émission par voie non filaire d'un flux d'informations numériques à partir d'équipements d'émission fixes disposés en des points déterminés dudit espace, ces informations numériques étant transmises sur une pluralité de canaux associés chacun à des contenus distincts. Chaque équipement d'émission émet de façon cyclique, contrôlée et en mode dit de streaming un flux distinct d'informations numériques. Chaque terminal de réception comprend des moyens agencés pour recevoir et diffuser directement les informations émises en mode dit de streaming. Utilisation pour la sonorisation indirecte de musées, d'expositions, de salons, de manifestations publiques, d'événements sportifs, pour le guidage dans des espaces de vente, des bâtiments publics et sièges d'entreprises, et en traduction simultanée.
Patent GB-2336365-A8 (GB)
Title: Woolgrease
Inventor: CAWTHORNE RICHARD NEIL
IPC: A61K8/00
Filed: 1998-01-14
Abstract: A process for recovering 18-methyl eicosanoic acid (18-MEA) and/or alpha hydroxy acids (AHAs) from woolwax acids or derivatives thereof comprises the steps of heating the woolwax acids or derivatives thereof to 100 to 230° C. to form estolides and polymeric species; distilling to obtain a distillate (D1) and a residue (R1); and recovering 18-MEA from the distillate and/or recovering AHAs from the residue.
Patent GB-2354061-A8 (GB)
Title: Cold storage appliance
Inventor: WOOD IAN DAVID
IPC: F25D25/02
Filed: 1999-09-13
Abstract: A cold-storage appliance comprises an open-topped insulating container defining an external surface, an insulating lid adapted to close the open top of the container, a cooling means adapted to cool the interior but not the exterior of the container, and a structure supporting the container, the lid and the cooling means. In accordance with the invention, the container is mounted to the structure for movement relative to the structure and the lid to open the container and afford access to its interior or to close the container, and at least a majority of the external surface of the container is exposed to ambient air when the container is closed by the lid.
Patent WO-2004080735-A8 (WO)
Title: 車両用サスペンションシステム
Inventor: KASAMATSU AKIRA
IPC: B60G21/055
Filed: 2003-03-12
Abstract: 本発明の目的は、液圧回路を含むロール抑制装置の異常を検出することである。　前輪側の液圧シリンダ３０と後輪側の液圧シリンダ６０との互いに対応する液圧室同士が液通路７２、７４によって接続される場合において、車両の横加速度に対応して決まる液圧に対して実際の液圧が低い場合には、液漏れが生じたとすることができる。車両のローリング状態と液圧との関係に基づけば、異常を検出することができるのである。異常が検出された場合に、電磁開閉弁１００，１０２が閉状態にされれば、２つの液圧シリンダ３０，６０が遮断される。液漏れが生じた一方の液圧シリンダまたは液通路の一部から他方の液圧シリンダを遮断することができる。他方の液圧シリンダにおいては、車両のローリング状態に応じた液圧差を発生させることができ、スタビライザバーに弾性力を発生させることができる。２つの液圧シリンダの両方が作用不能になる場合に比較して、ロール抑制効果の低下を抑制することができる。
Patent WO-0246936-A8 (WO)
Title: Procede et appareil permettant de communiquer avec un hote
Inventor: LEYDIER ROBERT ANTOINE
IPC: G06F3/00
Filed: 2001-12-03
Abstract: L'invention concerne un procédé et un appareil. Selon un mode de réalisation, une carte à puce comprend un circuit intégré doté d'un circuit de conditionnement de tension et d'une résistance d'excursion haute. Ladite carte est capable de signaler un hôte sur un bus au moyen de la résistance sélectivement couplée à une sortie de tension du circuit de conditionnement de tension et à une première sortie de la carte. La sortie du circuit de conditionnement est sélectivement couplée à la première sortie par l'intermédiaire de la résistance sensible à un dispositif alimenté par le bus mais sans transmission. La première sortie est ainsi amenée à l'état haut au niveau de tension de la source de tension, ce qui permet à l'hôte de détecter la carte lorsque le bus est commandé par un hôte. Il est avantageux de déconnecter sélectivement la résistance tout en transmettant et recevant des résultats dans une sortie plus équilibrée. Du fait que la résistance et le circuit de conditionnement sont partie intégrante du circuit intégré, il n'est pas nécessaire d'établir un contact séparé pour fournir la tension à la résistance, ce qui permet une compatibilité avec la configuration de contact de certaines cartes à puce existantes, et l'élimination de la résistance d'excursion haute ou du circuit de conditionnement dans un lecteur de carte.
Patent WO-02054330-A8 (WO)
Title: Techniques de gestion therapeutique pour dispositif medical implantable
Inventor: HARTLAUB JEROME T
IPC: G06F19/00
Filed: 2001-12-26
Abstract: L'invention concerne un procédé et un appareil destinés à ajuster automatiquement la vitesse de diffusion d'un médicament en vue d'optimiser un traitement thérapeutique. Un dispositif médical implantable communique avec une base de données ou un algorithme contrôlé par un fournisseur de soins ou un médecin, ce fournisseur de soins pouvant ainsi prescrire une modification dans le traitement (vitesse de diffusion par rapport au temps, paramètres temporels de pompe, etc.). Dans un autre cas, un module de gestion thérapeutique peut induire automatiquement cette modification de traitement à un moment donné dans le futur, que ce soit par commodité ou pour des raisons techniques ou cliniques.