baber/WOPTO huggingface dataset:
Patent EP-1716178-B1 (EP)
Inventor: KUFER PETER
IPC: A61P37/00
Filed: 2005-02-16
Granted: 2010-08-11
Abstract: The present invention provides a bispecific binding molecule, wherein said molecule comprises or consists of at least two domains whereby one of said at least two domains specifically binds to/interacts with the human CD3 complex and said domain comprises an amino acid sequence of an antibody derived light chain, wherein said amino acid sequence is a particularly identified amino acid sequence comprising specific amino acid substitutions, and a second domain is or contains at least one further antigen-interaction-site and/or at least one further effector domain. The invention further provides nucleic acid molecules encoding the bispecific binding molecules of the invention, vectors comprising said nucleic acid molecules and host cells transformed or transfected with said vectors. Moreover, the invention concerns a method for the production of bispecific binding molecules of the invention and compositions comprising the bispecific binding molecules of the invention, the nucleic acid molecules of the invention or the host cells of the invention.
Patent EP-1749149-B1 (EP)
Inventor: ZHANG HONG
IPC: F01N3/28
Filed: 2005-03-30
Granted: 2008-05-07
Abstract: Un moteur à combustion interne comporte une pluralité de cylindres et présente des soupapes d'injection qui sont associées aux cylindres et qui dosent le carburant à injecter. Une sonde de gaz d'échappement est placée dans un conduit de gaz d'échappement, le signal de mesure de cette sonde étant caractéristique du rapport air/carburant dans chaque cylindre. Un angle de détection (CRK_ SAMP) formé entre le vilebrequin et une position de référence du piston du cylindre respectif est déterminé pour détecter le signal de mesure, en fonction d'une grandeur caractérisant le rapport air/carburant dans le cylindre respectif ou en fonction d'une pression ambiante (AMP) ou d'un degré d'ouverture (OG_WG) d'une soupape d'un élément de dérivation vers une turbine qui est placée dans le conduit de gaz d'échappement. Le signal de mesure est détecté lorsque l'angle de vilebrequin est égal à l'angle de détection (CRK_ SAMP) et ce signal est associé au cylindre respectif.
Patent EP-1730152-B1 (EP)
Inventor: KUBOTA HITOSHI
IPC: A61K31/47
Filed: 2005-04-01
Granted: 2012-05-02
Abstract: Il est prévu un nouveau composé de la formule (I) : où R1 est un alkoxy carbonyle ou autre, R2 est un alkyle ou autre ; R3 est un hydrogène ou autre ; R4 est un alkylène ou autre ; R5 est un groupe hétérocyclique substitué en option ; R6, R7, R8 et R9 sont indépendamment de l'hydrogène ; un alkyle, un alkoxy, ou autre ; R10 est un anneau aromatique substitué en option, ou autre ; ou un sel acceptable pharmaceutiquement de celui-ci, ayant une activité inhibitoire contre la protéine de transfert d’ester cholestéryle (CETP).
Patent EP-1766805-B1 (EP)
Inventor: SUTIVONG ARAK
IPC: H04L1/00
Filed: 2005-06-07
Granted: 2009-08-19
Abstract: Techniques for adjusting transmit power to mitigate both intra-sector interference to a serving base station and inter-sector interference to neighbor base stations are described. The amount of inter-sector interference that a terminal may cause may be roughly estimated based on the total interference observed by each neighbor base station, channel gains for the serving and neighbor base stations, and the current transmit power level. The transmit power may be decreased if high interference is observed by a neighbor base station and increased otherwise. The transmit power may be adjusted by a larger amount and/or more frequently if the terminal is located closer to the neighbor base station observing high interference and/or if the current transmit power level is higher, and vice versa. The intra-sector interference is maintained within an acceptable level by limiting a received SNR for the terminal to be within a range of allowable SNRs.
Patent EP-1743178-B1 (EP)
Inventor: MARTINEAU PIERRE
IPC: G01N33/50
Filed: 2005-04-25
Granted: 2010-06-16
Abstract: The invention concerns a method for identifying a ligand capable of selectively modulating a functional cascade involving a target, and uses thereof for high-throughput screening of molecules of interest, in particular therapeutic (medicine). Said method comprises at least the following steps: a) identifying an antibody or an antibody fragment comprising at least one of the variable domains of an immunoglobulin chain, capable of binding to said target and modulating said functional cascade involving said target; b) screening from a bank of molecules, ligands modulating the bond between said target and the antibody or antibody fragment identified in a); and c) identifying among said modulating ligands obtained in b), those capable of modulating said functional cascade.
Patent EP-1776253-B1 (EP)
Inventor: SCHMALE UWE
IPC: B60N2/12
Filed: 2005-08-04
Granted: 2010-07-21
Abstract: A memory device for blocking a component configured to move between an adjusting position and a functional position is provided. The memory device includes a housing configured to be coupled to the component, a blocking element pivotally coupled to the housing and a variable transmission mechanism coupled to the housing. The variable transmission mechanism is configured to transfer the movement of the component to the blocking element as a variable transmission when the component is moved from the adjusting position toward the functional position. According to one exemplary embodiment, the component is an adjustable easy entry vehicle seat.
Patent EP-1781953-B1 (EP)
Inventor: RAUCH JOHANNES
IPC: F15B13/043
Filed: 2005-08-02
Granted: 2012-07-04
Abstract: L'invention concerne une soupape pilote, destinée notamment à une servo-soupape et comprenant un moteur de positionnement (6) et un préamplificateur hydraulique grâce auquel il est possible de générer une différence de pression de commande qui agit sur un tiroir principal (32) d'un étage principal (4). Selon l'invention, on réalise dans le chemin d'écoulement de l'huile de commande un dispositif d'arrêt (26) dont l'actionnement manuel permet de fermer un conduit de commande (14, 16) relié, directement ou par l'intermédiaire d'un embranchement, à une chambre de commande de l'étage principal, l'autre conduit de commande restant ouvert. L'actionnement du dispositif d'arrêt en sens inverse permet de fermer l'autre conduit de commande, le premier conduit de commande restant alors ouvert. Par l'actionnement de ce dispositif d'arrêt, on peut générer manuellement une différence de pression de commande grâce à laquelle le tiroir principal peut être déplacé dans une position prédéterminée.
Patent EP-1815502-B1 (EP)
Inventor: BRANZ KARSTEN
IPC: H01L21/00
Filed: 2005-10-28
Granted: 2011-11-16
Abstract: L'invention concerne un procédé pour traiter des substrats comprenant les étapes suivantes : formation d'une pellicule liquide sur une surface locale du substrat à traiter par une unité à buses comprenant au moins un dispositif à buses allongé et un dispositif transformateur d'ultrasons ou de mégasons adjacent à celui-ci ; mise en contact d'au moins une partie du dispositif transformateur d'ultrasons avec la pellicule liquide ; et introduction d'ultrasons dans la pellicule liquide, ainsi formée, au moyen du dispositif transformateur d'ultrasons.
Patent EP-1836204-B1 (EP)
Inventor: COMBA PETER
IPC: A61K103/00
Filed: 2005-12-08
Granted: 2009-10-21
Abstract: Radioactive metal chelate complexes (I) are new. Radioactive metal chelate complexes of formula (I) are new. A+B' = O, NR 1, S or CHR 1; or A = H and B' = OH, SH, NHR 1or CH 2R 1; R 1= alkyl, aryl, ester or amide, all optionally substituted; D = COOH or a derivative thereof, e.g. ester, amide or peptide; X, Y, Z = substituted pyridines (e.g. substituted with alkyl, halo or NO 2), other heterocycles, e.g. thiophene, furan, thiazole, imidazole or quinoline, or other groups with N, O or S functions; R = alkyl, aryl, ester or amide, all optionally substituted; M* = a radioactive metal; and m, n = 1-5. An independent claim is also included for a process for preparing (I). [Image] ACTIVITY : None given. MECHANISM OF ACTION : Internal radionuclide therapy.
Patent EP-1726393-B1 (EP)
Inventor: BRACH KURT
IPC: B23D61/02
Filed: 2006-05-17
Granted: 2010-05-05
Abstract: A circular saw blade (12) is provided with a first bore of a first size, configured for engagement with a first size arbor (CC). The disk (16,18) also has a second bore of a second size configured for engagement with a second size arbor (GG). The second bore is disposed concentrically with the first bore, and is placed within a knockout portion (20,22) of a disk secured to a face of the saw blade (12). The knockout portion (20,22) is removable for enlarging an inner transverse dimension (21) of the disk beyond that of the first bore (17). The second transverse dimension is within an ISO H7 standard tolerance. The disk is thus configured for mounting the second bore on the second size arbor, and alternatively for removing the knockout portion (20,22) to mount the first bore on the first size arbor.
Patent EP-1726237-B1 (EP)
Inventor: CLOS THOMAS
IPC: A46D3/00
Filed: 2006-05-26
Granted: 2011-03-23
Abstract: The brush has a grasp which is connected to a brush neck with a brush head. The head which is equipped with bristles (14) and has at their attachment-lateral ends a swollen part (16) connecting to a base (2). The swollen part is arranged between grasp, neck and head. The base has a brush head upper layer (10) and a brush head back layer (18). The brush head upper layer is towered, and functional elements (20) arranged at the brush head. The functional element is molded on to the brush head upper layer. An independent claim is included for a production method.
Patent EP-1717293-B1 (EP)
Inventor: HECKMEIER MICHAEL DR
IPC: C09K19/42
Filed: 2003-04-30
Granted: 2009-03-11
Abstract: Liquid crystalline medium (A) based on a mixture of polar compounds with positive dielectric anisotropy, comprises one or more polar aromatic compound (I) and 6 binuclear compounds e.g. (II) and (III). Liquid crystalline medium (A) based on a mixture of polar compounds with positive dielectric anisotropy, comprises one or more polar aromatic compound of formula (I) and 6 binuclear compounds of formulae e.g. (II) and (III). R 1>halogenated or unsubstituted 1-15C alkyl- or alkoxy group, where one or more CH 2 group in the residue is replaced by -Ctriple boundC-, -CH=CH-, -O-, -CO-O- or -O-CO-, where O atom is not connected directly; X : F, Cl, CN, or halogenated alkyl, alkenyl, alkoxy or 6C alkenyloxy group; L 1>, L 2>H or F; and R 2>, R 3>H, CH 3, C 2H 5 or n-C 3H 7. An independent claim is also included for an electro optical liquid crystal display containing (A). [Image] [Image].
Patent EP-1741578-B1 (EP)
Inventor: HEER SIEGFRIED
IPC: B60G17/052
Filed: 2006-07-05
Granted: 2010-05-19
Abstract: The control device includes several integrated electrical control units and several electrically controllable pre-control valves (6, 7) connected to and least one air supply valve (9) with blocking valves (10, 11). The electrically controllable transverse throttle (12) separates the airbags from each other in the blocked position.
Patent EP-1736060-B1 (EP)
Inventor: YAN NIANXI
IPC: A23L1/00
Filed: 2003-04-08
Granted: 2010-02-17
Abstract: Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment.
Patent EP-1920777-B1 (EP)
Inventor: NOOKANDEH-BAUMGAERTNER ASLIEH DR
IPC: A61P31/04
Filed: 2006-11-13
Granted: 2011-09-07
Abstract: Extraction process to classify extraction and separation of vegetable and/or animal component materials by multistage washing processes comprises (a) mincing the plant and/or animal component materials comprising plant and/or animal raw materials and/or providing the plant and/or animal raw materials in liquid form; (b) filling the extraction container with the obtained minced product; (c) carrying out a first continuous washing process with a first solvent or its mixture; and carrying out a second continuous washing process with second solvent or its mixture. Extraction process to classify extraction and separation of vegetable and/or animal component materials by multistage washing processes comprises (a) mincing the plant and/or animal component materials comprising plant and/or animal raw materials and/or providing the plant and/or animal raw materials in liquid form; (b) filling the extraction container with the minced plant and/or animal raw materials and/or with plant and/or animal raw material in liquid form, where the extraction container exhibits at least an inflow, at least a discharge, one or more support device for the minced material arranged before the discharge; (c) carrying out a first continuous washing process with a first solvent or its mixture; carrying out a second continuous washing process with second solvent or its mixture, where the first and second solvent or their mixture are different; and (d) optionally carrying out of further continuous washing processes respectively with a further solvent or its mixture, where each further solvent or its mixture are different. An independent claim is included for the hop extract obtained by the above process. ACTIVITY : Antimicrobial; Antibacterial. MECHANISM OF ACTION : None given.
Patent EP-1800918-B1 (EP)
Inventor: KLINGLER DIETRICH DIPL-ING
IPC: B60H1/34
Filed: 2006-12-13
Granted: 2009-09-09
Abstract: The vent has inner and outer air ducts (3, 2), and air conducting units (6A-6C) arranged in the air ducts. The outer air duct runs parallel to the inner air duct between inner and outer cylinders (4, 5), where a helix (6.1) is formed for producing an adjustable spinning flow by adjusting the air conducting units. The outer air duct is arranged as a ring tube and arranged around a central unit. A flap is arranged in the inner air duct and connected with an operating unit that is provided for adjusting the air conducting units.
Patent EP-1734578-B1 (EP)
Inventor: BRANDENBERG SCOTT D
IPC: H01L23/473
Filed: 2006-06-02
Granted: 2008-07-09
Abstract: A cooled electronic assembly includes an integrated-circuit device carrier (such as a printed circuit board), a device (such as a flip chip), a liquid pump, a molding material, a heat exchanger, and a cover. The device and the liquid pump are electrically connected to the integrated-circuit device carrier. The molding material is molded to the device, to the liquid pump, and to the integrated-circuit device carrier. The cover has a coolant channel fluidly connected to the heat exchanger, wherein the cover is attached to the molding material. The coolant channel and the heat exchanger together at least partially define a closed coolant circuit. The liquid pump is operatively connected to the closed coolant circuit. A method for cooling a printed circuit board includes placing a liquid coolant in the closed coolant circuit and electrically activating the liquid pump through the printed circuit board.
Patent EP-1716828-B1 (EP)
Inventor: LIAO GRACE
IPC: A61M1/00
Filed: 2006-03-30
Granted: 2008-05-21
Abstract: A surgical irrigation system is provided having reduced irrigation flow resistance. Reduction in irrigation fluid flow resistance is achieved by increasing the diameter of the irrigation fluid tubings (322). Short portions (321,323,325) near the ends of the tubings have a reduced diameter and are tapered to reduce the stiffness of the tubings and to allow the tubings to be connected to current surgical devices, including a cassette (327) and a handpiece (9).
Patent EP-1889995-B1 (EP)
Inventor: PEDERSEN PETER
IPC: E06B3/663
Filed: 2006-08-11
Granted: 2009-11-04
Abstract: A spacer (1) for forming a spacing between glass panes (41, 42) is basically formed by a plastic part (10) and a metal foil (30). The plastic part (10) has an inner wall part (11) and two lateral legs (12a, 12b) extending away from said wall part (11). The metal foil has an outer wall part (31) and two lateral (32a, 32b) which extends away from said wall part (31). An outer surface (19a, 19b) of said legs (12a, 12b) is at least partially covered by the side walls (32a, 32b) of the metal foil (30).
Patent EP-1690510-B1 (EP)
Inventor: WEBSTER WILTON W JR
IPC: A61M25/01
Filed: 2006-02-10
Granted: 2010-03-31
Abstract: An irrigated tip electrode (36) design includes a shell (90) generally surrounding a plug (96) which jointly define a chamber (37) that is fed with fluid by a lumen (62). The fluid is distributed to the outer surface of the tip electrode through fluid passages (59). The chamber (37) is advantageously isolated from a region of the tip electrode (36) occupied by electrical and/or electromagnetic components in the tip electrode (36). Lumens occupied by the these components terminate in blind holes (74,78) that have no communication with the chamber (37). 
In one embodiment, an irrigated tip catheter (10) comprises: a catheter body (12); a control handle (16); a tip section (14) at the distal end of the catheter body (12) and comprising a tip electrode (36) having: a shell (90) and a plug (96) jointly defining a chamber (37); a lumen (62) to pass fluid into the chamber (37); and at least one fluid passage (59) to pass fluid from the chamber (37) to outside the tip electrode (36).
Patent EP-1821559-B1 (EP)
Inventor: PECAN MARK
IPC: H04W48/18
Filed: 2006-02-16
Granted: 2010-04-21
Abstract: Apparatus, and an associated method, for selecting whether to authorize connection of a mobile station to communicate by way of a communication network. Radio frequency uncertainty, such as at coverage area boundaries, is managed to control better the selection. Signals broadcast by the communication system are monitored and signal performance metrics of the signals are identified. Average values of the performance metrics are identified, and rates of change of the performance metrics are calculated. When the average values are beyond a selected threshold and the rates of change are positive, authorization is granted to permit the connection of the mobile station to the communication network.
Patent EP-1712127-B1 (EP)
Inventor: MORISE TAISEI
IPC: A01K89/01
Filed: 2006-04-06
Granted: 2008-09-03
Abstract: A drag mechanism (7) is arranged between a spool (4) and a spool shaft (15) and includes at least one first drag washer (61), at least one second drag washer (62a, 62b) and a drag knob (63). The at least one first drag washer (61) has on an outer circumferential portion with at least one interlock protrusion (61a). The at least one second drag washer (62a, 62b) is arranged with respect to the first drag washer (61) along an axial direction of the spool (4). The drag knob (63) is configured to be threaded onto the spool shaft (15) to selectively adjust an amount of pressure acting on the first and second drag washers (62a, 62b).
Patent EP-1854357-B1 (EP)
Inventor: WEIMAR ERIC
IPC: A21B1/22
Filed: 2006-05-11
Granted: 2012-03-14
Abstract: The device has a baking chamber (1) delimited by a base, roof, lateral walls, rear wall (6) and a pivoting flap (19) movable between open and closed positions. The roof has an inorganic face (3a) made of inorganic asbestos cement and including evacuation orifices (3b) to evacuate baking steam towards a confinement zone (14). The base has a baking slab (7) to receive products to be baked. Resistors (9) are provided in the base and the roof, where the resistors of the roof are horizontally extended in the bottom of the zone.
Patent EP-1837266-B1 (EP)
Inventor: KOBAYASHI HIDEYUKI
IPC: B62D6/00
Filed: 2006-01-12
Granted: 2012-03-14
Abstract: La présente invention concerne un contrôleur de dispositif de direction à assistance électrique comprenant une unité de calcul de valeur d'instruction auxiliaire de direction qui est conçue pour calculer une valeur d'instruction auxiliaire de direction en fonction d'un signal de couple, ainsi qu'une unité de commande de régulation du courant qui est conçue pour calculer une valeur d'instruction de tension en fonction de la valeur d'instruction auxiliaire de direction et pour contrôler le moteur. Une force d'assistance est fournie à un système de direction. Le contrôleur comprend également une unité de mesure de couple d'auto-alignement qui est conçue pour entrer une vitesse angulaire et une accélération angulaire du moteur, la valeur d'instruction auxiliaire de direction et le signal de couple, afin d'obtenir un couple d'auto-alignement. Le couple d'auto-alignement obtenu par l'unité de mesure de couple d'auto-alignement est retourné à la valeur d'instruction auxiliaire de direction via une unité de rétroaction.
Patent EP-1848453-B1 (EP)
Inventor: ICZKIEWICZ JOANNA
IPC: A61P25/28
Filed: 2006-02-17
Granted: 2010-10-27
Abstract: Polypeptides which are an N- and/or C-terminally truncated fragment of the human osteopontin (hOPN) sequence or species variant, and which minimally have a 15 amino acid sequence corresponding to amino acids 138 to 152 of hOPN, and polynucleotides encoding said polypeptide, are useful for treatment or prevention of neurodegeneration.
Patent EP-1866209-B1 (EP)
Inventor: BORIANI SILVANO
IPC: B65B19/22
Filed: 2006-03-23
Granted: 2010-12-15
Abstract: A method and device for finishing packets having respective overwrappings of heat-shrink material, whereby the overwrappings are sealed about the respective packets and then heated to shrink and adapt to the configuration of the packets; after being heated, the overwrappings are cooled to set and so reduce the risk of damage to the overwrappings at subsequent processing stages.
Patent EP-1859204-B1 (EP)
Title: Humidifier with maximum decontamination
Inventor: NICOLAI LIONEL
IPC: F24F6/14
Filed: 2006-03-02
Granted: 2008-12-10
Abstract: The invention concerns a humidifier comprising a fogging ramp ( 14 ), a water source ( 10 ) for feeding the humidifying manifold, a pump ( 12 ) adapted to supply water under high pressure to the humidifying manifold, at least one particulate filter ( 50, 52 ) retaining the particles having a size greater than about 1mu and receiving water from the source, an ultrafiltration filter ( 18 ) receiving water from the particulate filter to retain microorganisms having a size greater than 0.2 mum, and a UV-C manifold chamber ( 20 ) including one or more UV-C lamps arranged in quartz sheaths for receiving water from the ultrafiltration filter and adapted to destroy micro-organisms whereof the size is greater than 0.2 mum. The device further comprises a metering pump ( 53 ) arranged next to the UV-C manifold chamber and regularly supplying biocidal or virucidal products to prevent a biofilm from being formed in the pipes between the pump and the humidifying manifold.
Patent EP-1869155-B1 (EP)
Inventor: SOUTER PHILIP FRANK
IPC: C11D3/37
Filed: 2006-04-12
Granted: 2010-09-29
Abstract: A liquid laundry detergent for improved grease and oil cleaning having a lipase enzyme, a modified polyethyleneimine polymer and a liquid carrier.