baber/WOPTO huggingface dataset:
Patent JP-H10501790-A (JP)
IPC: A61K31/70
Filed: 1995-02-23
Abstract: PCT No. PCT/AU95/00086 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Feb. 23, 1995 PCT Pub. No. WO95/22993 PCT Pub. Date Aug. 31, 1995A method as described for testing the susceptibility of a person to asthma. The person inhales an effective amount of sodium chloride, mannitol or another substance capable of altering the osmolarity of airway surface liquid in the subject. The substance is in the form of a dispersible dry powder containing an effective proportion of particles of a respirable size. The subject is then measured to detect airway narrowing which is indicative of a propensity for asthma. The same technique of dry powder inhalation can be used to test for the susceptibility of a person to rhinitus, to induce sputum and promote mucociliary clearance.
Patent JP-H11501329-A (JP)
Title: ゴナドトロピン放出ホルモン拮抗剤
IPC: A61K31/404
Filed: 1996-12-10
Abstract: (57)【要約】
ＧｎＲＨの拮抗剤として有用であり、従って男性及び女性の種々の性ホルモン関連症状及び他の症状の治療に有用であり得る、式（Ｉ）の化合物及びその医薬上許容し得る塩を開示する。
Patent JP-2000502523-A (JP)
Title: パワーリセット機能を有するネットワークハブ相互接続回路
IPC: G06F1/24
Filed: 1996-03-12
Abstract: (57)【要約】
コネクタ素子（２０，２２）の使用を介してスタック型構成の電気的コンポーネント（図３）を相互接続する回路（図５）である。回路（図５）は、所望のシーケンスでコンポーネントをパワーアップさせるべくスタックの電気的コンポーネント（図３）のパワーアップシーケンスを自動的にリセットするリセット回路（図７）を含む。また、回路（図５）は、スタックの各コンポーネントに対して固有の識別子を発生する識別回路（２６）、及びスタックの最初コンポーネントと最後のコンポーネントとの間で端末接続を選択的に確立する終結回路（図６）も含む。
Patent JP-H08509141-A (JP)
IPC: A61L27/00
Filed: 1994-04-12
Abstract: Catheters and other medical devices include a non-metallic member having paramagnetic ionic particles fixedly incorporated therethrough in order to provide enhanced detectability when viewed by magnetic imaging regardless of the orientation of the non-metallic member in the magnetic field. Catheters are usually formed from polymeric tubing, and the paramagnetic ionic particles are usually formed from paramagnetic ions incorporated with water or other proton-donating fluid into carrier particles, such as zeolites, molecular sieves, clays, synthetic ion exchange resins, and microcapsules. Catheters and other medical devices include a non-metallic member having small iron and/or superparamagnetic particles fixedly incorporated therethrough or thereover in order to provide enhanced detectability when viewed by magnetic imaging. Catheters are usually formed from polymeric tubing, and the iron and/or superparamagnetic particles at or near the surface of the catheter interact with the water protons of the surrounding patient's body to provide image enhancement regardless of the orientation of the polymeric or other non-metallic material in the magnetic field.
Patent JP-H09501121-A (JP)
IPC: B65F3/00
Filed: 1994-05-03
Abstract: A motor truck for use in collecting and processing solid waste material such as scrap tires. The truck includes a chassis including a cab; a body structure positioned on the chassis behind the cab and defining a storage chamber; a shredder mounted on top of the body structure forwardly of the storage chamber; a compactor positioned within the body structure beneath the shredder and forwardly of the storage chamber; and a conveyor system for conveying tires from a curbside location upwardly for discharge downwardly into the open upper end of the shredder. The shredded tires are discharged downwardly into the body structure rearwardly of the compactor, whereafter the compactor is actuated to stroke rearwardly and compress the tire shreds into the storage chamber. After the truck has visited a series of retail tire outlets and the storage chamber is full of tire shreds, the truck returns to a recycling center where a door at the rear of the storage chamber is opened and the compactor is utilized as an ejector to eject the tire shreds from the storage chamber. At the recycling center the tire shreds are processed to form a rubber crumb material and the rubber crumb material is combined with scrap plastic to form a rubber/plastic resin compound in pellet form.
Patent JP-2000504535-A (JP)
Title: アナログ―ディジタル変換
IPC: H03M1/06
Filed: 1997-10-20
Abstract: (57)【要約】
Ａ／Ｄ変換では、入力信号（ＩＮ）と少なくとも１つの基準レベル（ＲＥＦ）との各比較に基づいてディジタルコード（ＤＣ）を得る。Ａ／Ｄ変換特性を改善するために、入力信号（ＩＮ）と各基準レベル（ＲＥＦ）とを少なくとも１回の比較に対して入れ替えるようにする（ＳＷ）。ディジタルコード（ＤＣ）は、各極性及び大きさが少なくとも平均で、いずれの入替えにもほぼ無関係となるディジタル出力コード（ＤＯＣ）を得るように処理される（ＰＯＰＲ）。
Patent JP-2001505022-A (JP)
IPC: H04L12/56
Filed: 1997-12-02
Abstract: A method of maintaining a group call in a mobile communication system comprising a network infrastructure and mobile stations, the method comprising the steps of: establishing a group call in which a first mobile station is prioritized and the mobile stations participating in said group call communicate in speech items, the frame structure comprising time slots that a second mobile station sending a speech item employs in its speech item. In the method, the first mobile station is allocated time slots or time periods in which only the first mobile station can transmit signalling messages to the network infrastructure; the first mobile station and the third mobile stations are transmitted data indicating in which time slots of time periods only the first mobile station can send signalling messages to the network infrastructure; and the third mobile stations refrain from sending their signalling messages in the time slots or time periods allocated to the first mobile station.
Patent JP-H11502549-A (JP)
IPC: C11D1/29
Filed: 1996-02-20
Abstract: The present invention relates to the use of a liquid composition comprising a peroxygen bleach and a compound chelating copper and/or iron and/or manganese, for pretreating fabrics before said fabrics are washed, whereby the loss of tensile strength in said fabrics is reduced. The present invention further encompasses a process for pretreating soiled fabrics as well as compositions suitable to be used in said process.
Patent JP-H09512430-A (JP)
Title: Ｄｎａ配列
Inventor: CLARK ANTHONY JOHN
IPC: C12N15/09
Filed: 1995-05-02
Abstract: (57)【要約】
組換ヒト因子ＩＸの低い発現率は形質転換宿主等の異種発現システムにおける異常なスプライシングによるものである。異常なスプライス部位は、（ａ）１０８５番目のｍＲＮＡのヌクレオチドを含む供与部位；及び（ｂ）１５４７番目のｍＲＮＡのヌクレオチドを含む受容部位として同定された（なお、この際、ｍＲＮＡのヌクレオチドの番号は図面の図２を使用する）。改善された因子ＩＸ発現配列は、異常なスプライシング効果を防止または抑制し収率を向上するように、上記部位の少なくとも１つを操作により除去される。改善されたＤＮＡ配列は遺伝子治療においても有用である。
Patent JP-2001507157-A (JP)
Title: リチウム二次電池
IPC: H01M50/414
Filed: 1997-12-19
Abstract: (57)【要約】
１種またはそれ以上のアルカリ金属塩、１種またはそれ以上の非水性溶媒を含有しそして酢酸セルロース、酢酸酪酸セルロース、酢酸プロピオン酸セルロース、ポリフッ化ビニリデン−ヘキサフルオロプロピレンおよびポリビニルピロリドン−酢酸ビニルから選ばれた重合体により固定化された電解質を有するリチウム二次電池であって、該重合体が電解質システムの塩、溶媒および重合体の重量に基づいて多くとも１５重量％の量で使用されるのが好ましく、但し、ポリフッ化ビニリデン−ヘキサフルオロプロピレンの場合において、この重合体が電解質システムの塩、溶媒および重合体の重量に基づいて多くとも１２重量％の量で存在することを条件とする、前記リチウム二次電池。前記固定化された電解質は、電池区画室からの漏れに関する問題を起こさずそして前記電解質はまた、液体電解質を用いる電池について観察される利用率に一層近くに接近する容量利用を示す高い導電性を有する。この電解質はまた、電気化学的に安定である。
Patent JP-2001506960-A (JP)
Title: 濾過および吸着により極低温流体を精製する方法
IPC: F17C13/00
Filed: 1997-12-18
Abstract: (57)【要約】
本発明は、沸点Ｐｅを有する、液状、ガス状、超臨界状態、および／または２相状態の、ヘリウム、水素、ジュウテリウム（Ｄ２）、クリプトン、キセノン、ネオン、およびアルゴンからなる群から選ばれた極低温流体を、Ｐｅ 1 ＜Ｐｅである、沸点Ｐｅ 1 を有する少なくとも１種の不純物に関し、精製する方法であって、固体状態の少なくとも１種の不純物を機械的フィルターを用いて濾過する工程、および液状またはガス状の少なくとも１種の不純物を吸着する工程を具備し、少なくとも部分的に精製された極低温流体の少なくとも１部が回収され、前記流体は、多くとも約１ｐｐｂの前記不純物を含有する極低温流体の精製方法に関する。本発明はまた、この方法を実施する装置に関する。
Patent JP-H09500912-A (JP)
Title: イミダゾ〔１，５−ａ〕インドール−３−オンのイミダゾリルアルキル誘導体およびそれらの製造法
IPC: A61P25/22
Filed: 1995-05-02
Abstract: (57)【要約】
下記式（Ｉ）：
 ［式中、ｎは１、２または３であり；Ｒ、Ｒ 1 およびＲ 2 の各々は同じでも異なっていてもよく、水素、ハロゲン、ヒドロキシ、シアノ、Ｃ 1 〜Ｃ 6 アルキル、ＣＦ 3 、Ｃ 1 〜Ｃ 6 アルコキシ、Ｃ 1 〜Ｃ 6 アルキルチオ、ホルミル、Ｃ 2 〜Ｃ 6 アルカノイル、カルボキシ、Ｃ 1 〜Ｃ 6 アルコキシ−カルボニル、ニトロ、−Ｎ（Ｒ 4 Ｒ 5 ）（ここで、Ｒ 4 およびＲ 5 の各々は独立して水素、Ｃ 1 〜Ｃ 6 アルキル、ホルミルまたはＣ 2 〜Ｃ 6 アルカノイルである。）または（Ｒ 6 Ｒ 7 ）Ｎ−ＳＯ 2 基（ここで、Ｒ 6 およびＲ 7 の各々は独立して水素またはＣ 1 〜Ｃ 6 アルキルである。）であり；Ｒ 3 は式：ａ）
 またはｂ）
 ［式中、Ｒ 8 およびＲ 10 の各々は同じでも異なっていてもよく、水素またはＣ 1 〜Ｃ 6 アルキルであり、Ｒ 9 は水素、Ｃ 1 〜Ｃ 6 アルキルまたは窒素保護基である。］のイミダゾリル基である。］を有する新規の５ＨＴ 3 受容体拮抗薬化合物および薬学的に許容されうるそれらの塩が開示されている。
Patent JP-H10501788-A (JP)
Title: スパンデックス供給パッケージ
IPC: B65H55/04
Filed: 1996-04-01
Abstract: (57)【要約】
改善されたスパンデックス供給パッケージおよびその方法を提供する。パッケージは円筒状コアを有しており、その上に、その表面上に潤滑仕上げ剤を有するスパンデックスが巻かれている。巻き上げられたスパンデックスの最後の数１００メートルは、パッケージ内の巻き上げられたスパンデックスの総長さの約０．１〜０．５％を構成しており、パッケージ内の巻き上げられたスパンデックスの残りが有する表面上の仕上げ剤の量の半分より少ない量を有する。
Patent JP-2001512376-A (JP)
Title: 電気的な手持ち工作機械
IPC: B23D59/00
Filed: 1998-10-22
Abstract: (57)【要約】
ケーシング柄部（１０１）とケーシングヘッド（１０２）とを有する機械ケーシング（１０）と、交換可能な工具（１３）と、この工具（１３）を振動する往復運動に駆動する電気的な駆動装置（１１）とを備えた電気的な手持ち工作機械、特に手持ちのこ盤において、人間工学的に規定されたグップ位置をオン‐／オフスイッチ（２５）の近くに得るために、ケーシング柄部（１０１）がほぼ棒状に形成されており、かつ棒状のケーシング柄部（１０１）からケーシングヘッド（１０２）への移行領域内にくびれ（１０３）が設けられている。オン‐／オフスイッチは、くびれ（１０３）を握った際に握った手の親指がオン‐／オフスイッチの操作グリップ上に載せられるように柄部軸線より下方でケーシングヘッドの側部に配置されている。
Patent JP-2001511224-A (JP)
IPC: B31F1/12
Filed: 1998-02-05
Abstract: An adhesive for applying to a creping surface in the process for dry creping tissue paper is disclosed. The adhesive comprises cationic starch and optionally a polyvinyl alcohol and a water-soluble, thermosetting, cationic polyamide-epihalohydrin resin. The adhesive provides high adhesion and doctorability for dry creping.
Patent JP-2000510495-A (JP)
IPC: A61Q5/06
Filed: 1998-12-23
Abstract: A cosmetic composition having, in a cosmetically acceptable medium, at least one nonionic amphiphilic associative polyurethane, and at least one silicone containing quaternary ammonium groups.
Patent JP-2001524300-A (JP)
Title: バッテリ保護システム
IPC: H02J7/10
Filed: 1998-03-26
Abstract: (57)【要約】
バッテリ保護システム（２０）はバッテリパック（１５）を充電するためのプロセスを制御する。ヒステリシス比較器（５４）はバッテリパック（１５）を通って流れる充電電流を検知しかつ前記充電電流がある上限に到達した時前記充電電流を中断するため充電スイッチ（３１）をオフに切り換える。インダクタ（３４）によって次に過渡電流が発生される。ヒステリシス比較器（５４）がバッテリパック（１５）を通って流れる過渡電流を検知しかつ前記過渡電流が実質的にゼロに低下した時前記充電電流を再発生するために前記充電スイッチ（３１）をオンに切り換える。周期的に、バッテリ監視回路（４０）が前記充電スイッチ（３１）をオフに切り換えかつバッテリパック（１５）における各々のバッテリセルにかかるオープン回路電圧を測定する。あるバッテリセルのオープン回路電圧が完全に充電された電圧に到達したことに応じて、バッテリ監視回路（４０）は充電スイッチ（３１）をオフに切り換えて充電プロセスを終了する。
Patent JP-2001520744-A (JP)
Title: 測定経路の複屈折効果を補正しながら、空隙を測定する装置およびその方法
IPC: G11B5/60
Filed: 1998-03-30
Abstract: (57)【要約】
偏光に基づく光学飛び高さテスタに採用されるような、回転運動場ガラスディスク(20)における複屈折を測定および補正する装置およびその方法。偏光された光(1、3)はディスク(20)の頂部表面(24)上に衝突し、ディスクを通って反対表面(25)上の測定点(90)へ屈折され、同点から、光はディスク(20)を通って逆反射され、S偏光およびP偏光の両方を含むビーム(9)の状態でディスク(20)に存在する前に屈折され、両偏光は、S偏光とP偏光との間の位相差を測定する位相検出器(13)により検出される。測定点により規定される位置に関する位相θ G の変化は、ディスク(20)上の各位置についての複屈折パラメータｂ || およびｂ ⊥ を提供する。位相検出器(13)は、既存のビーム(9)および入射ビーム(3)により規定され、ディスク(20)について半径方向線(102)に直交する測定点(90)を通って描かれる入射平面(101)の間に規定される斜角ζにおける、位相θ G を測定する。
Patent JP-2000513128-A (JP)
Title: データ処理装置におけるオペレーティングシステムの転送方法
IPC: G06F12/109
Filed: 1998-04-16
Abstract: (57)【要約】
この方法は、コンフィグレーションやプロセスに依存しないメインメモリのアドレス指定の維持のもとに、仮想アドレスモードのみでサポートされているターゲットハードウエアＭ２上で、実アドレスモードでサポートされているソースハードウエア（Ｍ１）のためのオペレーティングシステムＯＳ１の使用を可能にする。この場合、仮想アドレス空間のうちの１つがメインメモリＨＳ２のプロセスに依存しないアドレス指定のために予約され、実アドレスモードに相応してソースハードウエアＭ２上で使用される。別個の制御プログラムＧＳＰは、転送されたオペレーティングシステムＯＳ２にターゲットハードウエアＭ２の例外条件Ｅｖ２への応答を可能にさせ、転送すべきオペレーティングシステムの実アドレスは、物理的メモリの別個の制御プログラムＧＰＳによって占有されていない空きメモリ上の予約されたアドレス空間にイメージングされる。
Patent JP-2000513388-A (JP)
IPC: A61K35/02
Filed: 1999-03-09
Abstract: The present invention relates to cosmetic or pharmaceutical compositions comprising a powder containing a water soluble carboxylated gum and a clay crosslinked with metal ions.
Patent NO-20014148-A (NO)
Inventor: RONG HARRY MORTEN
IPC: C07F7/16
Filed: 2001-08-27
Abstract: The present invention relates to a method for removing impurities from elemental silicon-containing residues from the processes of producing organochlorosilane and chlorosilane. The residues are subjected to magnetic separation to provide a relative pure non-magnetic fraction having an increased silicon content and a relatively impure magnetic fraction having a lower silicon content than the non-magnetic fraction.
Patent NO-20032282-A (NO)
Inventor: MUREN PETTER
IPC: B64C27/82
Filed: 2003-05-20
Abstract: The present invention discloses a rotor that enables an aircraft to be passively stable in hover. The rotor, having a generally fixed geometry is tiltably connected to its rotor shaft. The outer part of the rotor blades have a pitch fixed relative to the rotational plane, whereas the inner part of the rotor blades have a pitch fixed relative to a reference plane perpendicular to the rotor shaft.
Patent NZ-201784-A (NZ)
Title: Aqueous coating composition containing a polymeric binder and vermiculite
Inventor: PADGET J C
IPC: C08K9/00
Filed: 1982-09-01
Abstract: An aqueous coating composition for the corrosion-protection and/or fire-protection of substrates comprising a dispersion of chemically delaminated vermiculite lamellae in an aqueous solution or dispersion of a film-forming polymeric binder. Preferably the vermiculite lamellae are of size below 50 microns, especially below 20 microns, and the film-forming polymeric binder is in the form of a colloidal dispersion or emulsion of the polymer in water such as is commonly called a latex.
Patent NZ-202081-A (NZ)
Title: Water-soluble nonionic detergent composition
Inventor: PIERCE R C
IPC: C11D17/00
Filed: 1982-10-05
Abstract: A detergent composition consisting essentially of a water soluble mixture of higher alkyl glyceryl ether nonionic surfactants having the structural formula where R is a C8-C16 alkyl radical, and n has a value of 1, 2 and 3, with an n distribution of 12-49% n=1 ethers, 24-61% n=2 ethers and 6-59% n=3 ethers.
Patent NZ-210711-A (NZ)
Title: Pneumatic valve:cam operated spool actuates one-way valves in body and spool
Inventor: MARTIN J C
IPC: B61D9/02
Filed: 1984-12-21
Abstract: A penumatic valve which is suitable for use in controlling the operation of a penumatic drive system such as that used for raising and lowering the body of a dump truck. The valve is opened and closed by a slide member which is mounted in a cylinder formed in the valve housing. An air inlet passage opens into the cylinder and an air outlet passage and a vent passage open from said cylinder. A first flow control valve in the inlet passage which is operable to close to prevent and open to permit the passage of air from the inlet passage to the cylinder. A second flow control valve in the vent passage which is operable to close to prevent and open to permit the passage of air from said cylinder to the vent passage thereby to vent the outlet passage. The slide member is adapted to locate the first flow control valve in its closed position and the second flow control valve in its open position when in the first position and to locate the first flow control valve in its open position and the second flow control valve in its closed position when in the second position.
Patent NZ-223269-A (NZ)
Title: 11 beta-alkynyl-estrenes and -estradienes and also pharmaceutical compositions containing them
Inventor: OTTOW ECKHARD
IPC: C07J1/00
Filed: 1988-01-26
Abstract: 11 beta -substituted steroids of the formula   <IMAGE>     wherein A and B together represent a second bond between the 6-position and 7-position carbon atoms, or, respectively, are each H; X is O, two H atoms or hydroximino; Z is the residue of a pentagonal or hexagonal ring which is optionally substituted and optionally saturated; R1 is vinyl, C3-7-cyclo-1-alkenyl, phenyl, naphthyl or 5- or 6-membered heterocyclic aromatic having at least one N, O or S atom, each being unsubstituted or substituted by 1-3 halogen atoms, 1-3 C1-4-alkyl, C1-4-alkoxy, C1-4-acyl, C2-10-alkenyl, C1-4-acyloxy, phenyl, nitro, hydroxy, carboxy, cyanide, COOR4 or amino optionally substituted by 1-2 C1-4-alkyl; R2 is methyl or ethyl, R3 is H, Cl or methyl; and R4 is C1-4-alkyl optionally substituted by phenyl which itself is optionally substituted by C1-4-alkyl, C1-4-alkoxy, halogen or phenyl have valuable pharmacological properties.
Patent NZ-228249-A (NZ)
Title: Substituted thiazolidine-2,4-diones and pharmaceutical compositions
Inventor: CLARK DAVID ALAN
IPC: C07D417/14
Filed: 1989-03-07
Abstract: Hypoglycemic thiazolidine-2,4-dione derivatives <CHEM>  wherein the dotted line represents a bond or no bond;  V is -CH=CH-, -N=CH-, -CH=N- or S;  W is CH2, CHOH, CO, C=NOR or -CH=CH-;  X is S, O, NR<1>, -CH=N- or -N=CH-;  Y is CH or N; Z is hydrogen, (C1-C7)alkyl, (C3-C7)cycloalkyl, phenyl, naphthyl, pyridyl, furyl, thienyl or phenyl mono- or disubstituted with the same or different groups which are (C1-C3)alkyl, trifluoromethyl, (C1-C3)alkoxy, fluoro, chloro or bromo;  Z<1> is hydrogen or (C1-C3)alkyl;  R is hydrogen or methyl; and  n is 1, 2 or 3; a pharmaceutically acceptable cationic salt thereof; or a pharmaceutically acceptable acid addition salt thereof when the compound contains a basic nitrogen.
Patent NZ-230002-A (NZ)
Title: Process for the preparation of 2-thiocyanomethylthiobenzothiazole and product thereof
Inventor: CONAWAY LAWRENCE S
IPC: C07D277/74
Filed: 1989-07-19
Abstract: A process for the manufacture of 2-thiocyanomethylthiobenzothiazole. 2-Chloromethylthiobenzothiazole is reacted, in the presence of at least one glycol ether as a solvent for the reaction, with either an alkali metal or an ammonium thiocyanate at a temperature and for a time sufficient to produce the 2-thiocyanomethylthiobenzothiazole.
Patent NZ-235086-A (NZ)
Title: Production of neurotrophin-3 and compositions containing it; identification of similar factors
Inventor: HOHN ANDREAS
IPC: C12P21/00
Filed: 1990-08-29
Abstract: NT3 is a member of the DBNF gp. It is based in part on the identification of regions of nucleic acid sequence homology shared by BDNF and NGF. The regions of homology may be used to identify new members of the BDNF/NGF gene gp. See US application No. 400,591 filed 30 August, 1989. The purified NT-3 protein and its prodn. by growing a host cell comprising the DNA molecule are claimed. The protein may be glycosylated or unglycosylated. Antibodies to NT-3 are also claimed and are produced by immunising a host animal with a neurotrophin-3 protein or its fragment.
Patent NZ-237711-A (NZ)
Title: Diethylenetriaminepentaacetic acid monoamide derivatives and compositions
Inventor: GRIES HEINZ
IPC: C07C323/42
Filed: 1991-04-05
Abstract: Compounds of the general formula I <IMAGE>  in which     Z<1> and Z<2> in each case represent a hydrogen atom or the radical  -(CH2)m-(C6H4)q-(O)k-(CH2)n-(C6H4)<SB >l-(O)r-R,  in which     m and n denote the figures 0-20,   k, l, q and r denote the figures 0 and 1 and R denotes a hydrogen atom, an optionally OR<1>-substituted C1-C6-alkyl radical or a CH2COOR<1> group where R<1> denotes a hydrogen atom, a C1-C6-alkyl radical or a benzyl group,   R<2> represents a saturated, unsaturated, straight- or branched-chain or cyclic alkyl group having up to 20 C atoms, aryl group or aralkyl group substituted by a carboxyl group optionally esterified with a C1-C6-alkyl or benzyl radical, or by a sulphone group, R<3> represents a hydrogen atom or a saturated, unsaturated, straight- or branched-chain or cyclic alkyl group having up to 20 C atoms, aryl group or aralkyl group optionally substituted by a carboxyl group which is optionally esterified with a C1-C6-alkyl or benzyl radical, or by a sulphone group, X represents a hydrogen atom and/or a metal ion equivalent of an element of atomic number 21-29, 31, 32, 37-40, 42-44, 49 or 57-83, with the proviso that at least one of the substituents Z<1> and Z<2> represents a hydrogen atom, that - when n and l each represent the figure 0 - k and r do not simultaneously each denote the figure 1 and that, if desired, the radical of the acid groups is present as an ester or amide, and their salts with inorganic and/or organic bases, amino acids or amino acid amides, are useful pharmaceutical agents.y
Patent NZ-256279-A (NZ)
Title: 4-chloro-5-trihydrocarbylsilylthiophene-2-carboxylic acids, dimers, preparation of a 4-chloro-2-thiophene carboxylic acid and 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole- 1-carboxamide
Inventor: BURGESS LAURENCE E
IPC: C07D/
Filed: 1993-09-17
Abstract: PCT No. PCT/US93/08613 Sec. 371 Date Jul. 7, 1995 Sec. 102(e) Date Jul. 7, 1995 PCT Filed Sep. 17, 1993 PCT Pub. No. WO94/12505 PCT Pub. Date Jun. 9, 19944-Chloro-2-thiophenecarboxylic acid is made by forming a compound of formula (Ia), disclosed herein, wherein R3 is (C1-C6) alkyl, phenyl, or benzyl; converting the compound to a compound of formula (IVa), disclosed herein, and removing the silyl group R3Si-. The product is useful as an intermediate in making pharmaceutical products.
Patent NZ-267209-A (NZ)
Title: Substituted pyrrolidin-3-yl-alkyl-piperidine derivatives, preparation and pharmaceutical compositions thereof
Inventor: BURKHOLDER TIMOTHY PAUL
IPC: A61K31/4433
Filed: 1994-04-22
Abstract: The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.
Patent NZ-284905-A (NZ)
Title: Method for inducing T-cell tolerance to a tissue or organ graft by administering an allogeneic or xenogeneic cell and also an antagonist of the receptor of the T cell which inhibits interation of the ligand with the receptor; treatment of diabetes
Inventor: NOELLE RANDOLPH J
IPC: A61K39/00
Filed: 1995-04-25
Abstract: Disclosed is the use of: (a) an allogenic or xenogenic cell which expresses at least one donor antigen and which has a ligand on a cell surface which interacts with a receptor on a surface of a recipient T cell which mediates contact-dependent helper effector function, and (b) an antagonist of a receptor on the surface of a T cell which inhibits interaction of the ligand with the receptor, for the preparation of a pharmaceutical composition intended for inducing T cell tolerance to a donor tissue or organ in a recipient of the tissue or organ, such as in a method for treating diabetes comprising administering donor pancreatic islet cells.
Patent NZ-299852-A (NZ)
Title: Child resistant container attachment has finish portion with downwardly extending thread ring & attachment ring, closure & pushtabs
Inventor: HAMILTON PETER WORTHINGTON
IPC: B65D41/04
Filed: 1993-01-19
Abstract: A child resistant attachment for containers used for storing and dispensing potentially dangerous materials, such as medicament tablets or the like, the attachment being resistant to opening by children but readily openable by adults, particularly adults having impaired manual dexterity of their hands and/or fingers. In a particularly preferred embodiment, the attachment comprises a finish portion including thread ring with an integrally molded annular tab ring or collar generally concentric to the thread ring and a closure which is releasably secured to the thread ring by means of complementary screw threads. The tab ring or collar preferably includes a pair of resiliently deformable spring-like pushtabs containing vertical extensions which engage interlocking pawls on the innermost surface of the closure skirt when the closure is fully assembled onto the finish portion. To remove the closure, the opposed pushtabs must be depressed prior to applying unscrewing torque to the closure to disengage the pushtab extensions from the interlocking pawls on the closure. In a particularly preferred embodiment, the finish portion of the child resistant attachment of the present invention is integrally molded with the container in a ready to use configuration without the need for additional assembly or molding operations. Methods for producing the child resistant attachment and child resistant packages employing it are also disclosed.
Patent NZ-324742-A (NZ)
Title: Stabilisers for live vaccines comprising sucrose
Inventor: FANGET BERNARD
IPC: A61K47/00
Filed: 1996-12-20
Abstract: Stabilizers for live vaccines and attenuated mono- or multivalent live vaccines, stabilized vaccines containig such stabilizers, and methods for preparing such vaccines, are disclosed. Said stabilizers for vaccines containing one or more attenuated live viruses include one or more components selected from each of the following groups: amino acids, disaccharides, polyalcohols and buffer solutions, with the proviso that one component selected from the disaccharide group is saccharose.