baber/WOPTO huggingface dataset:
Patent CA-3125226-A1 (CA)
Inventor: GONG XIAOMING
IPC: A61K31/35
Filed: 2019-12-30
Abstract: L'invention concerne un médicament, une composition pharmaceutique ou un kit pharmaceutique pour l'immunosuppression, destinés au traitement d'états tels que le psoriasis, comprenant un dérivé de forskoline ou un sel de celui-ci et éventuellement un composé de prostaglandine ou un composé glucocorticoïde. L'invention concerne en outre un procédé d'immunosuppression, consistant à administrer un dérivé de forskoline ou d'un sel de celui-ci et éventuellement un composé de prostaglandine ou un composé glucocorticoïde. Les dérivés de forskoline s'avèrent prometteurs en tant que classe de médicaments à petites molécules pour obtenir une immunosuppression à l'aide de nouveaux mécanismes, dans le traitement d'états tels que le psoriasis, lorsqu'ils sont utilisés seuls ou en combinaison avec d'autres substances. Par comparaison avec des médicaments de première ligne à base d'anticorps, des dérivés de forskoline présentent des avantages significatifs en termes de processus et de prix, et ont une efficacité comparable et moins d'effets secondaires par comparaison avec le médicament de première ligne tel qu'un onguent à base de calcipotriol et bétaméthasone.
Patent CA-3126611-A1 (CA)
Inventor: JOHNSON ANDY
IPC: A61K38/00
Filed: 2020-01-16
Abstract: La présente invention concerne une formulation pharmaceutique comprenant (i) une quantité thérapeutiquement efficace d'une protéine bispécifique comprenant un récepteur de lymphocyte T (TCR) soluble et un scFV ; et (ii) un tensioactif. Le rapport en poids de tensioactif à la protéine est situé dans la plage allant de 0,75:1 à 1,5:1. La formulation peut en outre comprendre un agent gonflant et/ou un stabilisant. Une autre formulation pharmaceutique comprend (i) une quantité thérapeutiquement efficace d'une protéine bispécifique comprenant un récepteur de lymphocyte T (TCR) soluble et un scFV ; (ii) un agent gonflant ; et (iii) un stabilisant. Le rapport en poids du stabilisant à l'agent gonflant peut être supérieur à 1:1.
Patent CA-3126614-A1 (CA)
Title: Synthesis gas production by steam methane reforming
Inventor: MORTENSEN PETER MOLGAARD
IPC: C01B3/38
Filed: 2020-02-27
Abstract: The invention relates to a synthesis gas plant for producing a synthesis gas, where the synthesis gas plant comprising a reforming section arranged to receive said feed gas and provide a combined synthesis gas, wherein said reforming section comprises an electrically heated reforming reactor, a fired reforming reactor and an optional third reforming reactor. The reforming section is arranged to output a combined synthesis gas. An optional post processing unit downstream the reforming section is arranged to receive said combined synthesis gas stream and provide a post processed synthesis gas stream. A gas separation unit arranged to separate the combined synthesis gas stream or the post processed synthesis gas stream into a condensate, a product synthesis gas and an off-gas. At least a part of the off-gas is recycled from said gas separation unit to said one or more burners. The invention moreover relates to a process for producing synthesis gas from a feed gas comprising hydrocarbons.
Patent CA-3126651-A1 (CA)
Inventor: COLDWELL GUY RICHARD
IPC: A01N25/08
Filed: 2021-08-03
Abstract: A rodent control mixture includes a blended chewing gum, salt, fast rising yeast, and flavor additive such as alfalfa powder. The blended chewing gum may be a spearmint-flavored chiclet chewing gum blended into a powdered form. Relative weights of ingredients of the rodent control feed mixture include two weight units of the powdered gum, two weight units of the salt, one weight unit of the fast-rising yeast, and one weight unit of the flavor additive. A rodent control feed is formed by mixing the rodent control mixture with water and oil into a rodent food such as rolled oats. The rodent control feed is then placed into the burrow holes of the target rodent such as into gopher holes of a gopher burrow. Beneficially, the rodent control mixture and associated feed is less harmful to humans, domestic animals and wildlife than poisons such as Strychnine commonly utilized to kill rodents.
Patent CA-3128791-A1 (CA)
Inventor: MYLLYKOSKI JOHANNES
IPC: E02B15/04
Filed: 2020-02-06
Abstract: L'invention concerne un agencement de séparation (113) pour un dispositif de collecte des déchets flottants sur la surface de l'eau ou à proximité de la surface de l'eau. L'agencement de séparation comprend un premier bassin (111) et un moyen de séparation (113). L'eau contenant des déchets est acheminée vers le premier bassin par un agencement de transfert (104), comme un tuyau. Le dispositif est configuré de sorte que l'eau provenant de l'agencement de transfert présente un gradient de vitesse, c'est-à-dire que la section transversale de l'agencement de transfert présente des zones où les vitesses d'écoulement d'eau sont différentes. La composante de vitesse la plus rapide de l'eau a la concentration en déchets la plus élevée. Le premier bassin et le moyen de séparation sont configurés de sorte que, lorsque l'eau arrive au niveau du premier bassin, la plupart des déchets atteignent le moyen de séparation et ne bouchent pas les parois du premier bassin.
Patent CA-3129423-A1 (CA)
Title: Drug delivery compositions for ocular administration of therapeutics and methods of use thereof
Inventor: JIANG PENGFEI
IPC: A61K47/36
Filed: 2020-02-10
Abstract: The present disclosure relates to compositions, devices, and methods for delivery of protein therapeutics, e.g., intravitreal delivery of a protein therapeutic to the eye. In particular, the present disclosure describes drug-delivery devices for injection into the eye of a subject in need thereof comprising a capsule having a bi-layered wall and a therapeutic agent, wherein the therapeutic agent is initially present within a luminal space of the capsule. Methods of making and using these drug-delivery devices are also described.
Patent CA-3130579-A1 (CA)
Inventor: MARQUINO WAYNE
IPC: G21C9/06
Filed: 2020-02-19
Abstract: A passive containment cooling system (PCCS) for a nuclear reactor may include a first (SI) and a second stage condenser (S2) with channels (104, 114) in fluid communication between an inlet (102, 112) and an outlet header (106, 116). The inlet header (102) of the first stage condenser (SI) may receive a fluid mixture through a first inlet opening (InOl). The channels (104, 114) may condense water from the fluid mixture flowing through the channels (104, 114) from the inlet header (102, 112) to the outlet header (106, 116), respectively. The PCCS condenser may include a catalyst (108) in at least one of the outlet header (106) of the first stage condenser (SI) or the inlet header (112) of the second stage condenser (S2). The catalyst (108) may catalyze a reaction for forming water from hydrogen and oxygen to reduce amounts of hydrogen and oxygen gas in the PCCS.
Patent CA-3131927-A1 (CA)
Inventor: MA ZHONG
IPC: A61K31/506
Filed: 2020-03-06
Abstract: The disclosure relates to a method of treating a complement-related indication in a subject by inhibiting C5 activity within or beneath a tissue of the subject, the method comprising contacting the subject with a tissue-penetrating C5 inhibitor, wherein the tissue-penetrating C5 inhibitor comprises zilucoplan (RA101495) and wherein the tissue- penetrating C5 inhibitor permeates the tissue and/or diffuses across the tissue, thereby inhibiting C5 activity within or beneath the tissue.
Patent CA-3133259-A1 (CA)
Title: System and method for tracking a passive wand and actuating an effect based on a detected wand path
Inventor: KAWASH SAMEER
IPC: G06F3/03
Filed: 2014-02-21
Abstract: A system in accordance with present embodiments includes a source of electromagnetic radiation that operates to emit electromagnetic radiation into an active playing area. The system also includes a sensing device that operates to receive the electromagnetic radiation after being reflected from a retro-reflective material of an article positioned in the active playing area and operable to generate data based on receiving reflected electromagnetic radiation from a series of article positions. Further, the system includes a controller that operates to process the data generated by the sensing device to determine whether the series of article positions correlate to a stored gesture and output a control signal to actuate an effect when the series of article positions correlate to the stored gesture.
Patent CA-3133568-A1 (CA)
Inventor: SHACHAR YEHOSHUA
IPC: G01N29/02
Filed: 2020-02-04
Abstract: The illustrated embodiments include a method of operating a SAW sensor to detect a sample in a fluid which includes the steps of: providing a SAW sensor with a functionalized detection lane in a handheld, portable assay and sensor system; maintaining the functionalized detection lane of the SAW sensor dry until the sample is fluidicly disposed in the detection lane; fluidicly disposing the sample in the functionalized detection lane; removing fluid the functionalized detection lane to concentrate the sample in the functionalized detection lane to increase the probability of a specific antibody-antigen interaction; washing the functionalized detection lane so that substantially only the specific antigen-antibody interaction remains in the functionalized detection lane; removing fluid from the functionalized detection lane again; and measuring concentration of the sample while the functionalized detection lane is fluid-free.
Patent CA-3134203-A1 (CA)
Inventor: VASERMAN ELCHANAN
IPC: B65D77/00
Filed: 2020-05-20
Abstract: Various embodiments of a deflating device for transferring a liquid content from a squeezable supply container into a baby feeding device are disclosed.The said device is electrically powered and configured to allow for hands free transferring of the liquid content. In other embodiments of the disclosed subject matter, the liquid transferring process is manually driven.
Patent CA-3135123-A1 (CA)
Title: Unsteady seepage simulation method and system of natural gas reservoir
Inventor: WANG MENG
IPC: G01V9/00
Filed: 2021-01-19
Abstract: A method and a system for simulating unsteady seepage of a natural gas reservoir are provided, which includes: acquiring a pre-built unsteady seepage equation of a gas reservoir based on a pore network model; and calculating seepage field data of the preset pore network model according to the preset pore network model and the unsteady seepage equation of the gas reservoir.
Patent CA-3138070-A1 (CA)
Inventor: LALANCETTE DANIEL
IPC: F16L3/26
Filed: 2021-11-08
Abstract: A cable tray includes a pair of opposed side rails. Each of the pair of side rails includes an upper flange and a lower flange. A web portion extends between and interconnects the upper flange and the lower flange. The web portion includes an outer side and an inner side and a plurality of stiffeners protrude one or more of inwardly and outwardly therefrom. A plurality of spaced apart rungs extend between and connect the pair of opposed side rails.
Patent CA-3138100-A1 (CA)
Inventor: LONDESBROUGH DEREK JOHN
IPC: A61P25/24
Filed: 2020-04-17
Abstract: L'invention concerne des procédés de traitement d'un sujet dont l'état le nécessite, qui comprend l'administration au sujet d'une dose thérapeutiquement efficace de psilocybine. Les procédés décrits ici peuvent être utilisés pour traiter diverses maladies, divers troubles et divers états. Par exemple, ces procédés peuvent être utilisés pour traiter la dépression, les troubles neurocognitifs, le trouble du spectre autistique et/ou le trouble du déficit de l'attention/hyperactivité.
Patent CA-3143176-A1 (CA)
Inventor: O'HEERON PETE
IPC: C12N5/0797
Filed: 2020-06-12
Abstract: Des modes de réalisation de l'invention concernent des procédés et des compositions liés à la capacité de l'ARN à améliorer l'activité thérapeutique des fibroblastes. Dans certains modes de réalisation, l'administration de l'ARN double brin est réalisée en fournissant de l'acide polyinosinique-polycytidylique (poly(I:C)) ou un dérivé de celui-ci dans une concentration suffisante pour induire des propriétés thérapeutiques et/ou pour augmenter les propriétés thérapeutiques sur lesdits fibroblastes. Dans un mode de réalisation, une activité thérapeutique améliorée comprend l'augmentation de l'activité migratoire des fibroblastes; l'efficacité de l'angiogenèse; l'efficacité de la modulation immunitaire; la capacité de différenciation; la production d'un ou de plusieurs facteurs trophiques; et/ou la capacité à résister à l'apoptose.
Patent CA-3143333-A1 (CA)
Title: Ethylene-based polymer composition containing a triorganoaminophosphine
Inventor: CHAUDHARY BHARAT I
IPC: C08K5/5399
Filed: 2020-06-16
Abstract: The present disclosure provides a composition. The composition includes (i) an ethylene-based polymer; (ii) an organic peroxide, (iii) a triorganoaminophosphine, and (iv) a protic acid-source compound ("PASC") selected from a protic acid, a protic acid-generator compound ("PAGC"), and combinations thereof. The present disclosure also provides a coated conductor. The coated conductor includes a conductor and a coating on the conductor, the coating containing a composition including (i) an ethylene-based polymer; (ii) an organic peroxide, (iii) a triorganoaminophosphine, and (iv) a protic acid-source compound ("PASC") selected from a protic acid, a protic acid-generator compound ("PAGC"), and combinations thereof.
Patent CA-3143481-A1 (CA)
Title: Machine learning based phone imaging system and analysis method
Inventor: ANANDASIVAM KRISHNAPILLAI
IPC: G06N20/00
Filed: 2020-07-10
Abstract: A machine learning based imaging system comprises an imaging apparatus for attachment to an imaging sensor of a mobile computing apparatus such as camera of a smartphone. A machine learning (or AI) based analysis system is trained on images captured with the imaging apparatus attached, and once trained may be deployed with or without the imaging apparatus. The imaging apparatus comprise an optical assembly that may magnify the image, an attachment arrangement and a chamber or a wall structure that forms a chamber when placed against an object. The inner surface of the chamber is reflective apart and has a curved profile to create uniform lighting conditions on the one or more objects being imaged and uniform background lighting to reduce the dynamic range of the captured images.
Patent CA-3145741-A1 (CA)
Inventor: PRIEST RYAN
IPC: A63C9/085
Filed: 2019-07-08
Abstract: The present invention relates to a front ski binding assembly (1) for a ski board (S), the assembly comprising a front boot-retaining mechanism (3) for retaining a user's boot (B) in either a slope ascending or in a slope descending utilisation, said boot-retaining mechanism (3) o two first articulated arms (32a, 32b) pivotably mounted on a platform (2), o a lateral security release device (36) arranged in cooperation with first ends (34a, 34b) of the first articulated arms (32a, 32b) to apply thereon a biasing force urging second ends (35a, 35) of said first articulated arms (32a, 32b) towards the longitudinal axis (L) of the platform (2) and to allow each of said first articulated arms (32a, 32b) to rotate away from said longitudinal axis (L) upon application by a user's boot of a force higher than said biasing force on an interior surface of a said first articulated arm (32a, 32b), and o two second articulated arms (37a, 37b) pivotably mounted about a second arbor (39a, 39b) and bearing at an end touring pins (40a, 40b) to engage corresponding mating members (B1, B2) on front end sides of a user's boot in slope ascending utilisation, said second articulated arms (37a, 37b) being movable between an active position and an inactive position.
Patent CA-3147388-A1 (CA)
Title: System and method for providing fertility enhancing dietary and lifestyle recommendations
Inventor: MALIKOV EVGUENI
IPC: G16H10/20
Filed: 2020-07-29
Abstract: Methods and systems for generating evidence-based dietary and lifestyle recommendations are presented. In one embodiment, a method is provided that includes requesting and receiving a plurality of user attributes. The method may further include comparing the user attributes to corresponding evidence-based fertility benchmarks and determining fertility support opportunities based on the user attributes and the comparisons to the corresponding evidence-based fertility benchmarks. In an embodiment, the method may also include identifying fertility enhancing recommendations based on the fertility support opportunities, and presenting at least one of the plurality of fertility enhancing recommendations.
Patent CA-3147818-A1 (CA)
Inventor: GOUIN STEVE
IPC: B62B13/18
Filed: 2022-02-04
Abstract: An electric linear actuator and retractable wheel assembly configured for use on a snowmobile is provided. The assembly includes bracket or base member configured to be attached to a ski of a snowmobile. The base member supports a linear actuator which is activated to rotate a transfer plate. The transfer plate simultaneously slides and pivots around a transfer shaft which guides and limits the movement of the transfer plate. A wheel is attached to the transfer shaft such that the wheel is configured to retract and protract relative to the ski of the snowmobile allowing the wheel to be used instead of the ski when the snowmobile is traveling on rough surfaces.
Patent CA-3148029-A1 (CA)
Title: Element poreux pour systeme de fourniture de vapeur
Inventor: MOLONEY PATRICK
IPC: A24F40/46
Filed: 2020-07-21
Abstract: L'invention concerne un élément poreux (70) pour un système de fourniture de vapeur qui comprend une tige allongée (80) de matériau céramique poreux ayant une première face d'extrémité (86), une seconde face d'extrémité (88), et une ou plusieurs faces latérales (90) s'étendant entre la première face d'extrémité (86) et la seconde face d'extrémité (88) et définissant une longueur de la tige ; et un revêtement de métal (92) appliqué à au moins une face latérale (90) sur au moins une partie de la longueur de la tige.
Patent CA-3155045-A1 (CA)
Title: Device for selectively storing and mixing first and second liquids
Inventor: SYBROWSKY JOSHUA B
IPC: B65D47/20
Filed: 2019-10-16
Abstract: A device for selectively storing and mixing two liquids. The device comprises a first interior portion for storing a first liquid, a second interior portion for storing a second liquid, and a valve intermediate to the first and second interior portions. The valve moves between at least two positions, a first position preventing the first and second liquids from mixing, and a second position allowing the first and second liquids to mix. The valve includes a first member protruding from a first side and a second member protruding from a second side.
Patent CA-3155347-A1 (CA)
Title: Nanoparticules d'oxyde de fer enrobees de lipides pour otite moyenne
Inventor: SHAPIRO BENJAMIN
IPC: A61K33/24
Filed: 2020-10-22
Abstract: L'invention concerne une composition ayant des nanoparticules ayant des lipides ; un enrobage de polysaccharide, un agent actif et de l'oxyde de fer. L'agent actif peut être la ciprofloxacine ou la fluocinolone. L'invention concerne une méthode de traitement d'une maladie de l'oreille ou d'une infection de l'oreille comprenant l'administration d'une formulation pharmaceutique comprenant des nanoparticules et la poussée ou la traction magnétique des nanoparticules vers un site de traitement.
Patent CA-3156706-A1 (CA)
Title: Use of a composition comprising vitamin e tocotrienols for managing cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil)
Inventor: YUEN KAH HAY
IPC: A61K31/355
Filed: 2020-04-08
Abstract: The present invention provides use of a composition for the manufacture of a medicament for mitigating debilitating effects of Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), wherein the composition comprises vitamin E tocotrienols in a mixture of squalenes, phytosterols and pharmaceutically acceptable excipients.
Patent CA-3157113-A1 (CA)
Inventor: LEI GAI
IPC: F04D17/16
Filed: 2020-10-29
Abstract: A flow guide device, a centrifugal fan using the flow guide device, and a range hood. The flow guide device comprises a flow guide surface (231); a first curve segment (AD), a second curve segment (EA), a third curve segment (DF), and a first straight line segment (FE) jointly define the flow guide surface; a starting point (A) of the first curve segment serves as an origin of coordinates, two mutually perpendicular straight lines which pass through the origin of coordinates and are located on the plane where the first curve segment is located are respectively marked as an X axis and a Y axis, and a straight line perpendicular to both the X axis and the Y axis is marked as a Z axis, so that coordinates of an ending point (D) of the first curve segment are (x3,y3) and the inequalities x3?0 and y3?0 are satisfied, and Z coordinates of a starting point (F) and an ending point (E) of the first straight line segment are not equal to 0. The flow guide surface of the flow guide device is a curved surface formed by three curves, so that air flow can be effectively guided to turn, and turning energy loss and aerodynamic noise can be reduced.
Patent CA-3158271-A1 (CA)
Title: Portable mountable sports stick rack
Inventor: RICHARD AARON
IPC: A63B60/56
Filed: 2020-11-12
Abstract: There is provided a portable wall-mountable sports stick rack. The rack has a cornpliant support having a front side and an opposed rear side; a plurality of sports stick retaining channels along the front side adapted to receive a sports stick therethrough; and an adhesive layer associated with the rear side, the adhesive layer configured to removeably mount the sports stick rack to a wall surface.
Patent CA-3160659-A1 (CA)
Inventor: KANASTY ROSEMARY
IPC: A61K9/20
Filed: 2020-11-06
Abstract: Provided are gastric residence systems comprising: a core; a plurality of arms connected to the core at a proximal end through a plurality of linker components, one linker component of the plurality of linker components corresponding to each arm of the plurality of arms, and the plurality of arms extending radially from the proximal end, and a filament circumferentially connecting each arm of the plurality of arms.
Patent CA-3161866-A1 (CA)
Inventor: BROWN DONN J
IPC: F04D29/44
Filed: 2020-03-11
Abstract: An electric submersible pump (ESP) assembly. The ESP assembly comprises an electric motor, a centrifugal pump mechanically coupled to the electric motor, and a gas handling inverted shroud assembly.
Patent CA-3164864-A1 (CA)
Inventor: DIETZ GARRET
IPC: B65D81/20
Filed: 2021-01-27
Abstract: Sliced ready-to-eat meat are provided by slicing ready-to-eat meat, disposing the meat into a flexible pouch with a modified atmosphere, and sealing the flexible pouch containing the meat. The flexible pouch is formed from material having: i) a thickness of from about 0.2 mils to about 2 mils; ii) an MVTR of about 1.2 g/100 in 2 /24 Hrs @ 100°F, 90%RH, 1 atm or less; iii) an 02 Gas Transmission Rate of about 0.8 cc/100sqin/day or less at 1 atmosphere, 0% relative humidity and 73°F or less; and iv) a clarity of about 80% or greater.