baber/WOPTO huggingface dataset:
Patent AU-2020310141-A1 (AU)
Title: Compounds and methods for the treatment and prevention of fibrotic disease states and cancer
Inventor: LOW PHILIP STEWART
IPC: A61P11/00
Filed: 2020-07-08
Abstract: Compounds, pharmaceutical compositions and methods are provided for reprogramming M2-like macrophages to M1-like macrophages, which reverses the antifibrotic to profibrotic shift observed during the course of fibrotic diseases and certain cancers. The compounds comprise an immune modulator that targets a pattern recognition receptor of a cell and are specific to the cells of interest through the incorporation of a targeting moiety (
Patent AU-2020325054-A1 (AU)
Title: Hybrid amphotericin b derivatives with reduced toxicity
Inventor: BURKE MARTIN D
IPC: A61K31/7048
Filed: 2020-08-07
Abstract: Disclosed are C16 ester derivatives of C2'epi-amphotericin B (C2'epiAmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the C 16 ester derivatives of C2'epiAmB, therapeutic methods of using the C16 ester derivatives of C2'epiAmB, and methods of making the C16 ester derivatives of C2'epiAmB.
Patent AU-2020357771-A1 (AU)
Title: Single domain antibodies specifically binding globo - series glycans
Inventor: SEEBERGER PETER H
IPC: A61P35/00
Filed: 2020-10-02
Abstract: The present invention relates to the field of single-domain antibodies (sdAb) directed towards the glycans of the globo series, and in particular Globo H. More in detail, the present invention relates to sdAbs specifically binding one or more glycans selected from Globo H, Gb3, Gb4, and Gb5. The invention also provides polypeptides comprising multimeric single domain antibodies, as well as T cell chimeric antigen receptors comprising said anti-glycan sdAbs. Thus, the present invention provides polypeptides that can be used for targeting and/or treating several types of cancers associated with cells over-expressing said Globo H and /or Gb3, Gb4, Gb5. The present invention also relates to recombinant nucleic acid sequences encoding said polypeptides, and expression vectors and host cells comprising the same.
Patent AU-2020372712-A1 (AU)
Title: Synthesis of 3-nitro-N-(2,2,2-trifluoroethyl)-4-pyridinamine
Inventor: TAN HONGYU
IPC: C07D213/74
Filed: 2020-10-29
Abstract: The present invention relates to a chemical synthesis route for preparing 3-nitro-N-(2, 2, 2-trifluoroethyl)-4-pyridinamine (b) which compound can be used as an intermediate compound in the synthesis of RSV inhibiting imidazopyridines or imidazopyrimidines.
Patent AU-2020375706-A1 (AU)
Title: Poloxamer compositions with reduced sol-gel transition temperatures and methods of reducing the sol-gel transition temperature of poloxamer compositions
Inventor: SALAMONE JOSEPH C
IPC: A61K9/06
Filed: 2020-10-21
Abstract: The reduction in the sol-gel temperature of aqueous poloxamer surfactant compositions by the addition of hydrophobic vicinal diols is provided. Lowering of the sol-gel temperature and the gelling efficiency of water-soluble poloxamer block copolymers of polyethylene oxide-
Patent AU-2020408811-A1 (AU)
Title: Method for defining at least one boundary surface inside an artificial tooth element
Inventor: KIRSTEN ARMIN
IPC: A61C13/00
Filed: 2020-12-03
Abstract: The invention relates to a method for defining at least one boundary surface (16) inside an artificial tooth element, the method comprising the steps of: aligning the tooth element (10) with a coordinate system which preferably relates to anatomically defined directional terms; defining a first boundary curve (12) on the tooth surface; determining a tooth surface (14) located incisally/occlusally with respect to the first boundary curve; and moving this tooth surface (14) inwards in the direction of the surface normal by different amounts in order to produce the at least one boundary surface (16), in particular the first boundary surface (16), wherein the different amounts of the movement involve variable design parameters.
Patent AU-2020410375-A1 (AU)
Title: Substituted thiophene carboxamides and derivatives thereof as microbicides
Inventor: DUFOUR JEREMY
IPC: C07D401/12
Filed: 2020-12-17
Abstract: The present disclosure relates to substituted thiophene carboxamides derivatives, their use for controlling phytopathogenic microorganisms and compositions comprising thereof.
Patent AU-2020474910-A1 (AU)
Title: Pontoon for transporting and placing a marine wind turbine on the seabed
Inventor: COUÑAGO LORENZO BERNARDINO
IPC: E02B17/02
Filed: 2020-10-28
Abstract: Disclosed is a pontoon (111) for transporting and placing a one-piece marine wind turbine (115) on the seabed, wherein the one-piece wind turbine (115) comprises a base caisson (116) that can be fitted inside the open space of the U-shaped pontoon (111) for transporting, positioning and placing the base caisson (116) of the marine wind turbine (115) on the seabed, by ballasting the base caisson (116) and the U-shaped pontoon (111) in a synchronised manner using seawater.
Patent AU-2021200575-A1 (AU)
Title: Immunogenic products based on mutein amyloid ß (Aß) amino acid sequences and uses thereof
Inventor: BARGHORN STEFAN
IPC: A61K39/00
Filed: 2021-01-29
Abstract: IMMUNOGENIC PRODUCTS BASED ON MUTEIN AMYLOID f (Aft) 
AMINO ACID SEQUENCES AND USES THEREOF 
ABSTRACT 
The invention relates to immunogenic products based on muteinamyloid P(AP) amino acid 
sequences, in particular to oligomers of As muteins, and to the use of said products in 
diagnosis, treatment and prevention of conditions such as amyloidoses, and for identifying 
agents capable of binding to said products.
Patent AU-2021200788-A1 (AU)
Title: Gaming machine with fixed wild symbols and multiplier
Inventor: MORONEY JENNIFER
IPC: G07F17/32
Filed: 2021-02-08
Abstract: A method is disclosed for use with a gaming machine that is arranged to provide a 
spinning reel game. The method comprises the steps of stopping a spinning reel in 
5 order to display a symbol to a player, determining whether the symbol is a specified 
symbol and is adjacent another symbol that was held in a fixed display position while 
the reel was spinning and, if so, holding the symbol and the other symbol in fixed 
display positions during at least one subsequent reel spin.
Patent AU-2021201124-A1 (AU)
Title: Inner container made of plastic and transport and storage container for liquids having an inner container made of plastic
Inventor: Schütz Udo
IPC: B65D1/40
Filed: 2021-02-20
Abstract: The invention relates to an inner container (15) made of plastic for trans
5 porting and storing liquids, the inner container (15) having an outlet 
socket (18) for connecting an outlet fitting (17) on a front side, a bottom 
wall (20) connecting two side walls (23, 24), a rear wall (22) and a front 
wall (16) of the inner container (15) and serving to support the inner 
container (15) on a pallet floor (21) of a transport pallet (11) provided 
10 with an outer jacket (14) for receiving the inner container (15), and a top 
wall (25) located opposite the bottom wall (20) and provided with a fill
ing opening, wherein the side walls (23, 24) each have a horizontal cor
rugation (47, 48), the horizontal corrugations (47, 48) being disposed in 
a shared central horizontal plane.  
15 
(Fig. 2)
1/3 
27 25 10 
28 -12 
13 -14 
15 
Fig. 1 
21 
11 
23 -15 
-- 44 
51 5 Fig. 2 43 - -
43 - ___IM 
48 47 
46 45 
55 17 18 20 19 
15 39 40 
37 33 
31 
Fig. 3 29 h 
3834 
38 32 
36 35 30 30 41 42
Patent AU-2021201554-A1 (AU)
Title: Pyrrolo [1,2,f] [1,2,4] triazines useful for treating respiratory syncitial virus infections
Inventor: CLARKE MICHAEL O'NEIL HANRAHAN
IPC: A61K31/16
Filed: 2021-03-11
Abstract: C:\Interwo n\NRPortbl\DCC\RBR\18959687 _.docx-8/06/2019 
ABSTRACT OF THE DISCLOSURE 
Provided herein are formulations, methods and substituted tetrahydrofuranyl
pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (1) for treating Pneumovirinae 
virus infections, including respiratory syncytial virus infections, as well as methods and 
5 intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine 
compounds.  
R 2 NH 2 
N 
N 
RO5 -0 N 
R 
R 
/ R3 
R 6
Patent AU-2021204015-A1 (AU)
Title: Automatic association of medical elements
Inventor: BARNES ERIK
IPC: G16H40/40
Filed: 2021-06-17
Abstract: A system and method of associating a plurality of objects is disclosed. A physical 
space is defined and a real-time locating system (RTLS) is used to determine objects that are 
within the physical space. The objects determined by the RTLS to be within the physical 
space are associated. The objects include at least one of a caregiver, a patient, a medical 
device, a medication, and a medical substance.
1/8 
10 
16 
12 
18 
FIG.1
Patent AU-2021204124-A1 (AU)
Title: Three-Dimensional Reconstruction Method for Discrete Top Coal Particles of Intelligently Drawing Coals and System Therefor
Inventor: WANG JIACHEN
IPC: G06T17/00
Filed: 2021-06-18
Abstract: The present invention relates to a three-dimensional reconstruction method for discrete 
top coal particles of intelligently drawing coals and a system therefor. The method 
comprises the steps of: acquiring shape characteristics of discrete top coal particles at 
different views; determining a weighted average value and a visual angle difference 
index of the discrete top coal particles according to the shape characteristics of the 
discrete top coal particles at different views; generating corresponding convex hulls 
according to the particle sizes of the discrete top coal particles; acquiring shape 
characteristics of the convex hull at different views; determining a weighted average 
value and a visual angle difference index of the convex hull according to the shape 
characteristics of the convex hull at different views; determining a target convex hull 
corresponding to the discrete top coal particles according to the weighted average value 
and the visual angle difference index of the discrete top coal particles and the weighted 
average value and the visual angle difference index of the convex hull corresponding to 
the discrete top coal particles; carrying out voxelization and skeletonization on the 
target convex hull; and, reconstructing the discrete top coal particles according to the 
voxelized and skeletonized target convex hull. According to the present invention, 
particle reconstruction with high precision and low data redundancy is realized.
1/3 
Acquiring shape characerisikcs of discrete top coal particles at 
different views -I I 
Decermining a weighted average value and i visual angle difteciidnex of dthe 
discrete topcoal part jlesaccording to the shapecharacteristicsof the discrete lo Sl 02 
coalparticles at different views 
Generating corresponding convex hulls according to the partidlesies _ S103 
of the discrete top coal particles 
Acquiring shape characteristics of the convex hull at different ''aractci------o S 104 
views 
Determining a weighted average value and a visual angle 
difference index of the convex hull according to the shape Si05 
characteristics of the convex hull at different views 
Determining a target convex hull corresponding to the discrete top coal 
particles according Lo the weighted average value and the visual angle 
difference index of the discrete top coal particles and the weighted 
average value and the visual angle difference index of the convex hull 
corresponding to the discrete top coal paricles 
Carrying out voxelization and skeletonization on the target convex hull S107 
Reconstructing the discrete top coal particles according to the voxelized S I 
and skeletonized target convex hull 
FIG. 1
Patent AU-2021205051-A1 (AU)
Title: Compositions and methods for inhibiting the biological activity of soluble biomolecules
Inventor: HAWTHORNE LOUIS
IPC: A61K38/19
Filed: 2021-07-14
Abstract: The disclosure provides, among other things, compositions that bind to and inhibit the 
biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof.  
Also provided herein are a number of applications (e.g., therapeutic applications) in which 
the compositions are useful.
Patent AU-2021215192-A1 (AU)
Title: Temporary Stairway with Void Cover
Inventor: EDWARDS GRANT
IPC: E04G21/32
Filed: 2021-08-11
Abstract: A stairway assembly providing temporary access between two levels of a building 
5 under construction. The assembly extends from a lower floor to an upper floor at a 
location where the upper floor has a void formed therein to allow for later 
construction of a permanent stairway. The assembly includes a flight of stairs 
comprising: 
- a first frame portion comprising a pair of side rails with treads 
10 extending therebetween, and 
- attachment means at the top end of said first frame portion for 
attachment to the upper floor at an edge of said void.  
A trafficable void cover extends over said void and includes a first cover portion 
which is moveable from a lowered position to a raised position to thereby create a gap 
15 in said void cover. When the first cover portion is in said raised position, a person 
may climb the stairs and enter the upper floor through said gap whereas, when the 
first cover portion is in said lowered position it at least substantially covers said gap.
Patent AU-2021223703-A1 (AU)
Title: Molecules targeting proteins
Inventor: CLAES FILIP MARIA HENDRIK
IPC: G01N33/574
Filed: 2021-02-19
Abstract: Aspects of the invention concern non-naturally occurring molecules capable of downregulating the amount or biological activity specifically of mutant or variant forms of a protein, as well applications thereof.
Patent AU-2021237636-A1 (AU)
Title: Atmospheric plasma filter
Inventor: YANCEY PETER J
IPC: B01D53/00
Filed: 2021-03-17
Abstract: A plasma filter for treating a gas flow therethrough. The filter has a dielectric barrier plasma electrode assembly including a plurality of electrodes having a dielectric barrier layer coated thereon. The dielectric barrier plasma electrode assembly is configured to produce an atmospheric pressure plasma, A filtration medium is disposed on or between the electrodes, and a photocatalytic material is formed on surfaces of the filtration medium. Upon operation of the plasma filter, the plasma infiltrates voids in the filtration medium, and the gas flow7 through the filtration medium a) is exposed to reactive species of the plasma, b) interacts with the catalytic material, and c) is exposed to light generated from the plasma.
Patent AU-2021240069-A1 (AU)
Title: Hair clipper with pivoting bladeset for enhanced user visibility
Inventor: BUCK JR ROBERT N
IPC: B26B19/06
Filed: 2021-03-18
Abstract: A hair clipper configured for enhanced user visibility is provided, including a clipper housing (12) defining a longitudinal axis and a cutting end(14), a clipper bladeset (16) operationally connected to the cutting end and including a stationary blade (18) and a moving blade (22) configured for reciprocating laterally relative to the stationary blade, a drive system (28) projecting from the cutting end and operationally connected to the bladeset for reciprocating the moving blade relative to the stationary blade, at least one bladeset pivot support (50) projecting from the cutting end and connected to the bladeset; the pivot support defining a pivot axis extending transverse to the longitudinal axis.
Patent AU-2021244968-A1 (AU)
Title: Colour-strong manganese ferrite colour pigments
Inventor: ROSENHAHN CARSTEN
IPC: C09C1/24
Filed: 2021-03-12
Abstract: The present invention relates to colour-strong manganese ferrite colour pigments, to the production and use thereof.
Patent AU-2021245225-A1 (AU)
Title: Fan-shaped vehicle awning
Inventor: POZZI JOHN-DAVID
IPC: E04F10/04
Filed: 2021-10-08
Abstract: The invention relates to a vehicle awning (100) having an awning fabric (11) and awning 
arms (3, 3', 3", 3"'), which at their one end are pivotably mounted about a pivot axis (s, 
5 S2).
Patent AU-2021246213-A1 (AU)
Title: Gantry crane for containers and operating method
Inventor: BARBERÁ MAYOR JUAN CARLOS
IPC: B65G63/00
Filed: 2021-03-30
Abstract: Disclosed is a gantry crane for containers, with at least one elevated horizontal beam, which comprises: shipside spreaders, supported on a first section of the horizontal beam; landside container spreaders, supported on a second section of the horizontal beam; and a horizontal transport trolley, movably mounted along the beam, such that it can be placed under the containers lifted by the shipside spreaders, and which is arranged to support the containers and move them under the landside spreaders, the horizontal transport carriage comprising securing means to separably secure the containers.
Patent AU-2021257662-A1 (AU)
Title: Pharmaceutical composition for oral administration comprising aminopyrimidine derivative or pharmaceutically acceptable salt, hydrate, or solvate thereof
Inventor: MAXIMILIEN JACQUELINE
IPC: A61K31/5377
Filed: 2021-04-13
Abstract: Provided herein are pharmaceutical compositions for oral administration comprising N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-lH-pyrazol-l-yl)pirimidine- 2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide or a pharmaceutically acceptable salt, hydrate, or solvate thereof as an active ingredient; and a combination of (i) a cellulose derivative and (ii) a sugar or polyol as diluents. The disclosed compositions are characterized by improved manufacturability, while maintaining the pharmaceutical benefits of minimizing the effect according to changes in pH environment in the stomach, possessing excellent stability, and exhibiting good bioavailability.
Patent AU-2021275662-A1 (AU)
Title: Digital assistant user interfaces and response modes
Inventor: ELLIS NEAL
IPC: G06F3/0488
Filed: 2021-04-16
Abstract: An example process includes: while displaying a user interface different from a digital assistant user interface, receiving a user input; in accordance with a determination that the user input satisfies a criterion for initiating a digital assistant: displaying, over the user interface, the digital assistant user interface, the digital assistant user interface including: a digital assistant indicator displayed at a first portion of the display; and a response affordance displayed at a second portion of the display, where: a portion of the user interface remains visible at a third portion of the display; and the third portion is between the first portion and the second portion.
Patent AU-2021283044-A1 (AU)
Title: Parenteral nutrition formulation
Inventor: JEANNIN LAURENT CHRISTIAN
IPC: A61K9/107
Filed: 2021-05-27
Abstract: The present disclosure relates to parenteral nutrition formulations, including ready-to-use parenteral nutrition formulations which are reconstituted from multi-chamber containers and amino acid formulations. More particularly, the present disclosure is directed to formulations comprising butyrate derivatives, specifically arginine butyrate, for use with adult or pediatric patients. The disclosure further provides for methods of reducing or preventing systemic and local inflammation of patients receiving parenteral nutrition, and methods of maintaining or ameliorating their systemic immunity and local immunity, as well as the patients´ gut barrier functions.
Patent AU-2021291666-A1 (AU)
Title: Novel fused heterocyclic carbonohydrazonoyl dicyanide compound and use thereof
Inventor: PAE AE NIM
IPC: A61P25/28
Filed: 2021-06-18
Abstract: The present invention relates to a novel fused heterocyclic carbonohydrazonoyl dicyanide compound and a use thereof.
Patent AU-2021320658-A1 (AU)
Title: CD47 binding agents and uses thereof
Inventor: GLASER BRYAN
IPC: A61P35/00
Filed: 2021-08-03
Abstract: The present disclosure provides CD47 binding agents (e.g., antibodies, including multispecific antibodies, such as bispecific antibodies) and uses thereof.
Patent AU-2021323754-A1 (AU)
Title: Benzylamine derivative, preparation method therefor and use thereof
Inventor: XIAO JUNHAI
IPC: A61P35/00
Filed: 2021-07-28
Abstract: The present invention relates to a benzylamine derivative, a preparation method therefor and use thereof, and in particular, to a benzylamine derivative as represented by general formula (I), or a pharmaceutically acceptable stereoisomer, salt, solvate, or prodrug thereof, which has a strong binding capability with human PD-L1, can obviously inhibit the interaction of PD-1/PD-L1, and has significant anti-tumor efficacy in vivo. Therefore, the present invention also relates to a preparation method for the benzylamine derivative and use thereof in preparing a drug for treating PD-1/PD-L1-related diseases.
Patent AU-2021360120-A1 (AU)
Title: Process for extracting zirconium
Inventor: SOLDENHOFF KARIN
IPC: C01G25/00
Filed: 2021-10-12
Abstract: The present disclosure provides a process for extracting zirconium, in particular from a pregnant leach solution, which in preferred embodiments includes the removal of niobium from the solution to increase zirconium extraction. In particular, the process includes the steps of: a) contacting a pregnant leach solution containing at least zirconium and niobium with a solvent to create a zirconium loaded solvent and a raffinate; b) precipitating at least a portion of the niobium from the raffinate to create a barren liquor; c) contacting the barren liquor with further solvent to create a partially loaded solvent; wherein the partially loaded solvent following step c) is then used as at least part of the solvent in step a).
Patent AU-2021365721-A1 (AU)
Title: Synchronizing an external location
Inventor: YERFULE SOURABH
IPC: G06F16/188
Filed: 2021-07-09
Abstract: The present technology pertains to synchronizing contents of a directory external to a synchronized directory by a content management system. The content management system is configured to synchronize only objects in the synchronized directory. Accordingly, the present technology creates an anchor object that represents the directory external to the synchronized directory within the synchronized directory. The anchor object includes special attributes that indicate to the synchronization client that the anchor object represents an external directory, and allows the contents of that directory to be synchronized directly to a server on the content management system without first storing the contents of the external directory on the hard drive of the client device.
Patent AU-2021395243-A1 (AU)
Title: Safety drip chamber spike with breakable feature
Inventor: TAN BENJAMIN YANG TECK
IPC: A61M5/162
Filed: 2021-12-06
Abstract: An intravenous (IV) spike for administering a medicinal fluid from a container may include a head portion at a proximal end thereof, a base portion at a distal end thereof, and an elongate body portion connecting the head and the base portions. The elongate body portion may be configured to be coupled to the container. The IV spike may further include a radial notch extending at least partially along a circumference of an outer surface of the elongate body portion. The radial notch may be recessed radially inward from the outer surface.
Patent AU-2021400017-A1 (AU)
Title: Oral treatment device
Inventor: TAO LILI
IPC: A46B15/00
Filed: 2021-10-25
Abstract: An oral treatment device is provided. The oral treatment device comprises image sensor equipment operable to generate image data representing at least a portion of an oral cavity of a user. The oral treatment device comprises a controller configured to process the generated image data to identify an interproximal gap between adjacent teeth in the oral cavity of the user. The controller is configured to compare at least one characteristic of the identified interproximal gap with at least one characteristic of one or more previously identified interproximal gaps of the oral cavity of the user. The controller is configured to control the oral treatment device to perform an action based on a result of the comparison.