baber/WOPTO huggingface dataset:
Patent CA-3091543-A1 (CA)
Inventor: MICOL ROMAIN
IPC: A61K31/7088
Filed: 2019-02-19
Abstract: La présente invention concerne une séquence d'ARNm isolée pour l'expression d'un ou plusieurs polypeptides dans un ou plusieurs organes cibles, la séquence comprenant au moins une séquence de codage qui code pour l'au moins un polypeptide, au moins une première séquence de région non traduite (UTR) et une pluralité de séquences de sites de liaison de microARN (miARN). Chacune des séquences de site de liaison de miARN est située dans, immédiatement en 5' de ou immédiatement en 3' de, la première séquence UTR ; et les séquences de sites de liaison de miARN permettent l'expression différentielle de la séquence codante dans au moins un premier et un deuxième type de cellule dans l'organe ou les organes cibles. L'invention concerne en outre des procédés d'utilisation de la composition, en particulier dans le traitement d'une maladie, telle que le cancer du foie, du cerveau, du poumon, du sein, du pancréas, du côlon et du rein.
Patent CA-3094813-A1 (CA)
Inventor: DEATS MARY C
IPC: F02B77/11
Filed: 2018-03-20
Abstract: A thermal barrier material is disclosed for applications such as heat shields in automobiles and other vehicles. The thermal barrier material is made on a Fordenier paper making machine from a slurry that is very low in organic compounds that can cause smoke and odor when exposed to high temperatures. A first thermal barrier material is disclosed that can withstand up to 650°C and a second thermal barrier material is disclosed that can withstand up to 1000°C, in each case, the barrier material withstands it max temperature specification while producing extremely iow quantities of smoke and extremely low levels of offensive odors. Prior art thermal barrier materials with similar temperature specifications on the other hand produce many times the smoke and offensive odors at the same temperatures and do so for a far longer time.
Patent CA-3097531-A1 (CA)
Inventor: WOODALL ANDREW
IPC: H04W4/02
Filed: 2020-10-28
Abstract: Embodiments of the present disclosure are directed to systems and methods for a restaurant payment. The restaurant payment system includes a mobile computing device and an interface device communicatively coupled to the mobile computing device. The interface device includes a processing device, and a processor-readable storage medium in communication with the processing device storing one or more programming instructions that, when executed, cause the processing device to receive, by the mobile computing device, a location of a dining service, display, on the mobile computing device, a plurality of restaurants located within a predetermined radius of the determined location of the dining service, receive, by the mobile computing device, a bill for the dining experience, determine a plurality of information included on the bill, and display, on the mobile computing device, the plurality of information included on the bill.
Patent CA-3098751-A1 (CA)
Title: Detonator module
Inventor: MACGILLIVRAY JOSEPH
IPC: E21B43/1185
Filed: 2020-02-03
Abstract: Docket No: 2069464-0819PTWO (8997) 2019-IPM-103882 Ul PCT AB STRACT A detonator module provides for the use of a wide range of different addressable switches for use in perforating guns. The detonator module permits pre-assembly of a desired addressable switch and conforms the electrical connectivity to a particular perforating gun.  In this manner, nearly any addressable switch can be used from any manufacturer despite having different sizes or wiring layouts. The pre-assembled detonator module can be safely shipped due to a safety shunt that can be removed on site prior to installation into a perforating gun. In one sense, the detonator module permits conformance of multiple different types of addressable switches to a particular type or model of perforating gun, permitting flexible choice of addressable switch for a particular project.   Date Recue/Date Received 2020-11-09
Patent CA-3100694-A1 (CA)
Inventor: O'BRIEN CHRISTOPHER F
IPC: A61P25/18
Filed: 2019-06-13
Abstract: Methods are provided herein for treating psychiatric disorders relating to 22q11.2 deletion syndrome and for selecting subjects for treatment with a VMAT2 inhibitor. The methods provided herein comprise administering a VMAT2 inhibitor to a subject in need thereof.
Patent CA-3103161-A1 (CA)
Inventor: YUILLE SAMANTHA
IPC: A61P43/00
Filed: 2019-06-25
Abstract: L'invention concerne des compositions comprenant des souches bactériennes destinées à être utilisées en thérapie.
Patent CA-3103339-A1 (CA)
Inventor: MA MINGLIN
IPC: C09D133/26
Filed: 2019-06-18
Abstract: The present application relates to copolymers of N-halamine (HA) and dopamine (DMA) and their method of formation. The HA and DMA are present in the copolymer in a ratio of 0.4:9.6 to 9.6:0.4 (HA: DMA). The copolymers can be used in novel antimicrobial compositions that can be coated, and covalently bonded to surfaces such as metal, plastic, glass, or paint surfaces. The coating provides a rechargeable antimicrobial surface with the treatment of a halogen. The coating thickness and halogen content can be tuned by adjusting the formulation and crosslinking the coating.
Patent CA-3106656-A1 (CA)
Inventor: MOYANO DANIEL F
IPC: C09D175/04
Filed: 2019-07-18
Abstract: The present invention is directed to curable film-forming compositions comprising a first film-forming polymer prepared from at least one hydrophobic monomer, a second film-forming polymer prepared from at least one hydrophobic monomer, and a curing agent. Upon application of the curable film-forming composition to a substrate to form a coating layer, the first film-forming polymer is distributed throughout the coating layer, and the concentration of the second film-forming polymer is greater at the surface of the coating layer than the concentration of the second film-forming polymer within the bulk of the coating layer. The invention is additionally drawn to substrates coated with the curable film-forming composition. The present invention is also drawn to methods of mitigating dirt build-up on a substrate, comprising applying to at least a portion of the substrate the curable film-forming composition described above and at least partially curing the curable film-forming composition.
Patent CA-3106869-A1 (CA)
Title: Intraocular delivery of gene therapy expression vectors
Inventor: SIEVING PAUL ALBERT
IPC: A61F9/00
Filed: 2019-07-18
Abstract: Methods of administering a gene therapy construct to the eye including injection of the construct into the eye and application of an electric current to enhance penetration of or cellular expression of molecules in ocular tissues. These methods provide effective technique for the intraocular delivery of gene therapy vectors, especially AAV vectors, and nanoparticles.
Patent CA-3107600-A1 (CA)
Inventor: KARBOWNICZEK JACEK GRZEGORZ
IPC: A61B5/15
Filed: 2005-05-06
Abstract: ABRÉGÉ : Il est décrit un dispositif lancette qui comprend un logement et une structure de lancette dotée d'un élément perforant. La structure de lancette placée à l'intérieur du logement est adaptée pour se déplacer entre une position de retenue ou de préactionnement dans laquelle l'élément perforant est retenu dans le logement, et une position de perforation dans laquelle l'élément perforant s'étend à travers une extrémité avant du logement. Le dispositif lancette possède un ressort d'entraînement qui est placé dans le logement de manière à solliciter la structure de lancette vers la position de perforation, et un collet de retenue qui retient la structure de lancette dans la position rétractée contre la sollicitation du ressort d'entraînement. Le collet de retenue comporte un levier pivotant placé en ajustement serré avec la structure de lancette. Un actionneur situé dans le logement fait pivoter le levier, ce qui déplace la structure de lancette vers l'extrémité arrière du logement pour comprimer au moins partiellement le ressort d'entraînement, et libère le levier de son ajustement serré avec la structure de lancette. Date reçue/Date Received 2021-02-01
Patent CA-3110398-A1 (CA)
Inventor: OSTEN KAREL JOHN
IPC: C22B3/44
Filed: 2019-09-26
Abstract: A method for recovering NiSO4.6H2O crystals from a nickel rich organic phase is provided. The method includes contacting a nickel rich organic phase with an aqueous strip solution of sufficient H2SO4 concentration to extract nickel from the organic phase and of sufficient Ni2+ concentration to precipitate NiSO4.6H2O crystals and form a nickel lean organic phase. Also provided are methods for recovering NiSO4.6H2O crystals that include preceding processing steps, including low temperature pressure oxidation (LTPOX) autoclaving of a nickel sulphide concentrate to afford a pregnant leach solution (PLS).
Patent CA-3111273-A1 (CA)
Inventor: KJAER KATRINE
IPC: C12N7/00
Filed: 2019-09-06
Abstract: The present invention provides storage optimized aqueous compositions comprising a poxvirus suitable as poxvirus vaccine and pharmaceutical compositions, in particular liquid compositions or liquid frozen compositions, and methods of making them.
Patent CA-3112888-A1 (CA)
Title: Ball-mapping system and method of operating the same
Inventor: PINEAULT JAMES
IPC: G01N23/20025
Filed: 2019-09-12
Abstract: A ball-mapping system connectable to an X-ray diffraction apparatus, for collecting X- ray diffraction data at measurement points located on a ball-shaped sample is provided. The system includes a sample stage, including a sample-contacting surface and a guide assembly cooperating with the sample-contacting surface for guiding the sample-contacting surface along a first axis and along a second axis unparallel to the first axis. The system includes a sample holder for keeping the ball-shaped sample in contact with the sample stage and a motor assembly in driving engagement with the guide assembly, the motor assembly driving the sample-contacting surface in translational movement along the first axis and the second axis, the translational movement of the sample-contacting surface causing the ball-shaped sample to rotate, on the sample-contacting surface along the first axis and the second axis. A method for mapping the ball-shaped sample is also provided.
Patent CA-3113412-A1 (CA)
Title: Thermal control systems for aircraft landing gear wheel wells and related methods
Inventor: CLARK ANDREW DAVID
IPC: B64C25/00
Filed: 2021-03-26
Abstract: Thermal control system for aircraft main landing gear wheel wells and related methods are disclosed. An example thermal control system includes a conduit defining a fluid passageway between an inlet and an outlet. The inlet of the conduit positioned in fluid communication with a landing gear wheel well and the outlet of the conduit positioned in fluid communication with the atmosphere. The conduit generates a pressure differential through the fluid passageway between the inlet and the outlet to exhaust heat from the landing gear wheel well to the atmosphere.
Patent CA-3117419-A1 (CA)
Inventor: SATHER BLYTHE D
IPC: A61P35/00
Filed: 2019-10-31
Abstract: Provided herein are adoptive cell therapy methods involving the administration of doses of cells for treating disease and conditions, including certain plasma cell malignancy. The cells generally express recombinant receptors such as chimeric antigen receptors (CARs) specific to B-cell maturation antigen (BCMA). In some embodiments, the methods are for treating subjects with multiple myeloma (MM). Also provided are genetically engineered cells containing such BCMA-binding receptors for uses in adoptive cell therapy.
Patent CA-3117735-A1 (CA)
Inventor: LI MING
IPC: C12N9/24
Filed: 2019-11-20
Abstract: Provided are improved methods for treating wheat flour with lipase. Further provided are methods for separating wheat flour to provide a gluten fraction, a starch fraction and a fibre fraction where the wheat flour is treated with a selected lipase. Polypeptides having lipase activity, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides are also provided.
Patent CA-3118780-A1 (CA)
Inventor: HARTMAN ADAM
IPC: A61K9/00
Filed: 2019-11-13
Abstract: The invention provides respirable dry powder particle formulations comprising polynucleotides preferably prepared by spray drying for delivery to the pulmonary system via inhalation. Preferably, the polynucleotide is RNA.
Patent CA-3121035-A1 (CA)
Inventor: HATAMIAN MEHDI
IPC: G01N33/566
Filed: 2019-11-27
Abstract: La présente invention concerne un dispositif de dosage à écoulement latéral qui comprend un tampon de conjugué pour recevoir une quantité de fluide ; et une membrane comprenant une ligne de test pour déterminer si le fluide comprend un analyte cible. Dans un premier état du dispositif de dosage à écoulement latéral, le dispositif de dosage à écoulement latéral est configuré avec un espace amovible entre le tampon de conjugué et la membrane qui est sensiblement rempli d'air et qui empêche le fluide de s'écouler du tampon de conjugué dans la membrane. Dans un second état du dispositif de dosage à écoulement latéral, l'espace amovible est retiré entre le tampon de conjugué et la membrane, amenant ainsi le tampon de conjugué à entrer en contact avec la membrane, permettant au fluide de s'écouler du tampon de conjugué dans la membrane et la ligne de test par action capillaire.
Patent CA-3121137-A1 (CA)
Title: Predictive system for request approval
Inventor: BERTAGNOLLI NICOLAS M
IPC: G06Q40/08
Filed: 2019-11-22
Abstract: A computer implemented method includes receiving a text-based request from a first entity for approval by a second entity-based compliance with a set of rules, converting the text-based request to create a machine compatible converted input having multiple features, providing the converted input to a trained machine learning model that has been trained based on a training set of historical converted requests by the first entity, and receiving a prediction of approval by the second entity from the trained machine learning model along with a probability that the prediction is correct.
Patent CA-3122872-A1 (CA)
Title: Benzamides de derives de pyrazolyl-amino-pyrimidinyle, compositions et procedes associes
Inventor: Wan Zhaokui
IPC: C07D403/00
Filed: 2019-12-16
Abstract: L'invention concerne une nouvelle classe d'inhibiteurs de JAK disponibles par voie orale et/ou topique, sélectifs et puissants servant d'agents thérapeutiques sûrs et efficaces contre diverses maladies et divers troubles. L'invention concerne également une composition pharmaceutique contenant ces composés ainsi que des procédés de préparation et d'utilisation associés.
Patent CA-3123872-A1 (CA)
Title: Polypeptides activateurs de plasminogene de type urokinase modifies et leurs procedes d'utilisation
Inventor: MADISON EDWIN LEWIS
IPC: C12N9/72
Filed: 2019-12-27
Abstract: L'invention concerne des polypeptides u-PA et des protéines de fusion contenant les polypeptides u-PA. Les polypeptides u-PA sont modifiés pour présenter une activité et/ou une spécificité modifiées de façon à cliver une protéine du complément, telle que la protéine C3 du complément, pour inhiber ainsi l'activation du complément. Les polypeptides u-PA-1 modifiés et les protéines de fusion qui inhibent l'activation du complément peuvent être utilisés pour le traitement de maladies et d'affections médiées par l'activation du complément, ou dans lesquelles l'activation du complément joue un rôle. Ces troubles comprennent des troubles ischémiques et de reperfusion, notamment l'infarctus du myocarde et l'accident vasculaire cérébral, le sepsis, les maladies auto-immunes, les rétinopathies diabétiques, la dégénérescence maculaire liée à l'âge, le rejet d'organe transplanté, les maladies inflammatoires et les maladies avec un composant inflammatoire.
Patent CA-3124377-A1 (CA)
Inventor: ITO JUNJI
IPC: C12P7/06
Filed: 2018-11-05
Abstract: This invention is intended to improve the ethanol fermentation ability of a yeast strain having xylose-metabolizing ability with the use of a mutant gene encoding a mutant protein comprising a consensus sequence comprising a substitution of amino acid in the 30th position in SEQ ID NO: 1, amino acid in the 43rd position in SEQ ID NO: 4, and amino acid in the 31st position in SEQ ID NO: 7 with other amino acid residues.
Patent CA-3126146-A1 (CA)
Inventor: OLCUM SELIM
IPC: G01N33/483
Filed: 2020-01-10
Abstract: In silico tools are used to determine possibly effective therapies for treating a patient's cancer based on patient, drug, and cancer information. Functional assays can be performed on living cancer cells from the patient to evaluate the possibly effective therapies along with subsequent genomic or other more destructive assays to provide additional information from a single sample. Drug, patient, cancer, and outcome information can be recorded and updated iteratively and analyzed using machine learning to identify correlations between various patient, cancer, and drug characteristics and expected outcomes and drug efficacies.
Patent CA-3126465-A1 (CA)
Title: Switch identification circuit and electric device
Inventor: LEI YUN
IPC: H02J13/00
Filed: 2020-07-20
Abstract: A switch identification circuit is provided. The switch identification circuit includes an identification unit, a detecting unit, a control unit, a connection unit, a first connection terminal, and a second connection terminal. The identification unit is electrically coupled with the first connection terminal and the second connection terminal, and is configured to provide a conductive loop when the first connection terminal and the second connection terminal are short-circuited. The detecting unit is electrically coupled with the first connection terminal and the second connection terminal, and is configured to detect a voltage at the first connection terminal to output a first detection signal and detect a voltage at the second connection terminal to output a second detection signal. The connection unit is electrically coupled with a power-supply device configured to provide a driving voltage to the first connection terminal and the second connection terminal. The control unit is configured to determine whether the first connection terminal and the second connection terminal are short-circuited according to the received first detection signal and the received second detection signal. On condition that the first connection terminal and the second connection terminal are short-circuited, the control unit is configured to output a connection-enabling signal to the connection unit, to make the connection unit control the power-supply device to stop supplying the driving voltage. An electric device is further provided. The electric device includes the above switch identification circuit.
Patent CA-3128705-A1 (CA)
Title: Methods of improving myocardial performance in fontan patients using udenafil compositions
Inventor: YEAGER JAMES L
IPC: A61P9/00
Filed: 2015-06-30
Abstract: The invention addresses the following needs in the art: (i) improved therapies relating to complications or side effects of the Fontan procedure with the goal of increasing the life span of Fontan patients, and avoiding or delaying the need for cardiac transplantation, and (ii) improved therapies to delay the onset of cardiac failure and/or to improve the quality of life for patients who have had the Fontan procedure. The invention relates to methods of treating, preventing, or minimizing conditions, symptoms, or side effects associated with a subject who has previously had a Fontan procedure. In particular, the methods of the invention are directed to the use of udenafil or a pharmaceutically acceptable salt thereof in single ventricle patients that have undergone the Fontan procedure for the amelioration of associated acute symptoms and chronic symptom development.
Patent CA-3129066-A1 (CA)
Title: Articulated radiation shielding system
Inventor: FOSTER ROBERT EVANS
IPC: A61B6/10
Filed: 2020-02-07
Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography. The assembly is articulated to overcome difficulties in maneuvering it around an operating room. Such articulation may come in the form of a dual-sleeve configuration for jointing the shield, in the form of adjustable wheels on the floor stand, or both.
Patent CA-3129783-A1 (CA)
Inventor: KIRK TODD WILLIAM
IPC: B01D35/00
Filed: 2021-09-02
Abstract: A filtering apparatus has a volume-changeable filtering chamber having one or more flexible enclosing walls and receiving therein a compressible porous filtering medium, a fluid inlet coupled to the filtering chamber for introducing an input fluid stream with impurities into the filtering chamber, a fluid outlet coupled to the filtering chamber for discharging a filtered fluid stream from the filtering chamber, and a volume-changing structure coupled to or in association with the filtering chamber, adapted to permit increasing or decreasing of the volume of the filtering chamber so as to compress or decompress the compressible porous filtering medium therein so as to correspondingly adjust the pore size of the compressible porous filtering medium in said filtering chamber. A method for flushing a compressible filter media, and a method of variably adjusting the amount of filtering, is further disclosed and claimed.
Patent CA-3129853-A1 (CA)
Title: An headphone system
Inventor: KARKERA NAVAJITH PADMANABHA
IPC: H04R3/04
Filed: 2020-01-27
Abstract: An headphone system with improved sound reproduction capability is disclosed. The system includes a housing; a receiver configured with the housing and to receive audio signals from one or more computing devices; a control circuitry configured with the housing. A frequency of each of the received audio signals is determined by extracting audio attributes from the received audio signals. Then the determined frequency of each of the received audio signals is compared with a predefined threshold. In response to the comparison, the received audio signals are segregated into at least two set of signals including a first set of audio signals and a second set of audio signals. The first set of audio signals is converted into a first set of vibration signal energy and a second set of audio signals is converted into a second set of vibration signal.
Patent CA-3130919-A1 (CA)
Title: Windmill electrical power system and torque enhanced transmission
Inventor: WASHINGTON JERRY D
IPC: F03D15/00
Filed: 2021-09-15
Abstract: The present specification relates to power generation systems that generate, transmit, store, convert, transform, combine many forms of energy using a Torque Enhanced Transmission. The mechanism named Torque enhanced Transmission has multiple speed stages each having layshafts for connecting an auxiliary torque enhanced electrical machine to store energy. The power bus allows multiple combinations of input output power devices. The Torque enhanced transmission combines AC and CC generators together in one system that can generate or operate asa motor to drive the system and a marine vessel. A motorized vehicle or marine vessel can use the system as a large electric motor generator or use the components independently. The present invention relates generally to systems and methods for generating power using any energy source while generating power in multiple forms.
Patent CA-3130930-A1 (CA)
Title: Procedes et systemes d'evaluation d'echantillons cellulaires
Inventor: YUN KYUSON
IPC: C07K16/30
Filed: 2020-03-18
Abstract: La présente invention concerne des procédés et des systèmes pour évaluer des échantillons cellulaires, y compris des échantillons de tissus, tels que des tissus cancéreux. Dans certains cas, l'évaluation d'échantillons cellulaires comprend l'évaluation longitudinale d'une ou de plusieurs molécules candidates. L'invention concerne des procédés et des systèmes pour évaluer la viabilité cellulaire.