baber/WOPTO huggingface dataset:
Patent EA-201600400-A1 (EA)
Title: Противоопухолевая фармацевтическая композиция, содержащая темозоломид, и способ ее получения
IPC: A61P35/00
Filed: 2016-05-02
Abstract: Изобретение относится к области фармацевтики, конкретно - к противоопухолевой фармацевтической композиции, содержащей темозоломид, и может быть использовано в медицине, в частности в онкологии. Задачей изобретения является создание противоопухолевой фармацевтической композиции, содержащей темозоломид, которая характеризуется высокой эффективностью, обладает улучшенной стабильностью, обеспечивает высокую доступность противоопухолевого агента к опухолевым клеткам, и разработка способа ее получения. Поставленная задача решается тем, что противоопухолевая фармацевтическая композиция пролонгированного действия для лечения онкологических заболеваний, содержащая темозоломид и фармацевтически приемлемые носители, отличается тем, что в качестве фармацевтически приемлемых носителей композиция содержит фосфаты полисахаридов в солевой и кислой формах при следующем содержании компонентов, мас.%: темозоломид - 5-20; фосфат полисахарида - 30-80; фосфат полисахарида в кислой форме - до 100.
Patent EA-201790689-A1 (EA)
Title: Способы производства бумажных изделий с использованием многослойной крепирующей ленты и бумажные изделия, изготовленные с использованием многослойной крепирующей ленты
IPC: D21H27/00
Filed: 2015-09-25
Abstract: Предложен способ крепирования целлюлозного полотна, и этот способ включает получение зарождающегося полотна из водной бумагообразующей композиции; нанесение и крепирование зарождающегося полотна на многослойной крепирующей ленте, которая включает: (i) первый слой (502), выполненный из полимерного материла, имеющий множество отверстий (506), и (ii) второй слой (504), прикрепленный к поверхности первого слоя, причем зарождающееся полотно наносят на первый слой; и прикладывание вакуума к крепирующей ленте так, что зарождающееся полотно втягивается во множество отверстий, но не втягивается во второй слой.
Patent EA-201792604-A1 (EA)
Title: Ингибиторы аутотаксина и их применения
IPC: C07D401/14
Filed: 2016-05-24
Abstract: В настоящем документе описываются способы и композиции для лечения состояний, заболеваний и нарушений, ассоциированных с активностью аутотаксина. Способы и композиции, раскрываемые в настоящем документе, включают применение по меньшей мере одного соединения ингибитора аутотаксина.
Patent EA-201891246-A1 (EA)
Title: Способ маркирования подложки
IPC: D21H21/48
Filed: 2016-11-24
Abstract: Настоящее изобретение относится к способу маркирования подложки скрытым, детектируемым методом спектроскопии, защитным элементом, в котором жидкостная обрабатывающая композиция, содержащая по меньшей мере одну кислоту, наносится на подложку, которая включает по меньшей мере одну наружную поверхность, содержащую солеобразующее соединение щелочного или щелочно-земельного металла.
Patent EA-201892577-A1 (EA)
Title: Применение антитела к pd-1 в комбинации с антителом к cd30 в лечении рака
IPC: C07K16/28
Filed: 2017-06-01
Abstract: Настоящее раскрытие относится к способам лечения опухоли у субъекта, предусматривающим введение субъекту антитела к PD-1 и антитела к CD30. Согласно некоторым вариантам осуществления опухоль происходит из лимфомы (например, лимфомы Ходжкина или неходжкинской лимфомы). Согласно определенным вариантам осуществления антитело к CD30 представляет собой конъюгат антитела и лекарственного средства, например брентуксимаба ведотина.
Patent EA-201990392-A1 (EA)
Title: Процесс получения композиций иммуноглобулинов
IPC: C07K1/22
Filed: 2017-07-26
Abstract: Настоящее изобретение относится к способу получения фармацевтически приемлемых композиций иммуноглобулинов из полученных из плазмы фракций иммуноглобулинов, позволяющему параллельное получение композиций иммуноглобулинов, обогащенных IgG, IgM и IgA. По этому способу иммуноглобулин, содержащийся в фракции Кона I/II/III или фракции Кистлера/Нитшманна A+I, ресолюбилизируют при проводимости по меньшей мере 1 мСм/см и после удаления загрязняющего белка ресолюбилизированный иммуноглобулин подвергают анионообменной хроматографии для получения обогащенных IgG и IgM/IgA композиций иммуноглобулинов. Обогащенную IgG композицию иммуноглобулинов дополнительно подвергают обработке с использованием катионообменного материала для получения композиции иммуноглобулинов, имеющей уменьшенное содержание пропердина.
Patent EA-201991150-A1 (EA)
Title: Фильтры для курительных изделий с меньшей потерей добавки (добавок)
IPC: A24D3/16
Filed: 2017-12-08
Abstract: Настоящее изобретение относится к усовершенствованиям в фильтрах для курительных изделий, включающих произвольно ориентированные дискретные волокна. Эти усовершенствования относятся главным образом к потерям добавки (добавок) в упомянутых фильтрах и к изготовлению упомянутых фильтров.
Patent EA-201992848-A1 (EA)
Title: Блок питания для аэрозольного ингалятора, а также способ управления и программа управления данным блоком питания
IPC: A24F47/00
Filed: 2019-12-26
Abstract: Блок питания для аэрозольного ингалятора содержит источник питания, выполненный с возможностью разряжать энергию в нагрузку для образования аэрозоля из источника аэрозоля; блок управления, выполненный с возможностью управления источником питания; и датчик, выполненный с возможностью выдачи значения, зависимого от оставшегося заряда источника питания. Блок управления определяет короткое замыкание источника питания по выходному значению датчика.
Patent EA-202091189-A1 (EA)
Title: Способ и устройство для размыкания маршрута при компьютерной блокировке и компьютерный носитель информации
IPC: B61L27/00
Filed: 2018-05-07
Abstract: В настоящем изобретении предложен способ размыкания маршрута при компьютерной блокировке (CI - Computer Interlock). Способ включает этап, на котором оценивают, въезжает ли нормально поезд в текущую замкнутую секцию; этап, на котором в том случае, когда результат оценки является положительным, оценивают, выезжает ли поезд из указанной текущей замкнутой секции; этап, на котором в том случае, когда результат оценки является положительным, оценивают, разомкнута ли задняя секция за указанной текущей замкнутой секцией; и этап, на котором в том случае, когда результат оценки является положительным, размыкают указанную текущую замкнутую секцию. В соответствии с настоящим изобретением можно точно определять, проходит ли нормально поезд через замкнутую секцию, а также не происходит ошибочной оценки, что тем самым обеспечивает безопасность движения. Также предложены устройство для размыкания маршрута при CI и компьютерный носитель информации.
Patent EA-202190794-A1 (EA)
Title: Лента жгута для наконечника электронной сигареты, наконечник для электронной сигареты, способ изготовления ленты жгута для наконечника электронной сигареты и способ изготовления наконечника электронной сигареты
IPC: A24D3/10
Filed: 2018-10-25
Abstract: Лента жгута для наконечника электронных сигарет представляет собой жгут из ацетата целлюлозы, полученный путем объединения и обжатия множества нитей в жгут, причем общий весовой номер в денье установлен на значение в диапазоне от 10000 до 40000 (включительно), а весовой номер в денье нити установлен равным значению в диапазоне от 6,0 до 20,0 (включительно), и если общий весовой номер в денье обозначен как TD, а прочность на разрыв ленты жгута обозначена как F, соотношение F/TD установлено равным значению 0,0015 Н/денье или более.
Patent ES-2170652-A1 (ES)
Title: Gas volume correction system
Inventor: CUESTA CASES JAVIER
IPC: G01F1/50
Filed: 2000-04-07
Abstract: Gas volume correction system designed to independently manage one or more distinct measurement units dispersed geographically, and give users all of the necessary information via various access methods.The system includes a remote station/correction (2) that collects from the measurement units the measuring and consumption information and processes and stores it in the historical archives. For its part, the control centre requests all the necessary data from the remote station/corrector (2) to can update its databases. The user can query these databases locally using a local, personal computer.
Patent ES-2161643-A1 (ES)
Title: Composite tile with natural stone face, for decorative purposes, has natural stone part fixed to rigid supporting sheet having composition adapted to physical characteristics of natural stone
Inventor: SEGURA PASTOR JUAN JOSE
IPC: B32B3/12
Filed: 2000-04-27
Abstract: Composite tile is new. The novel composite tile has a visible face made of natural stone, and comprises a plate of reduced thickness natural stone (preferably marble), firmly fixed to reinforce and stiffen the support layer by means of an adhesive. The supporting layer is made of a lightweight plate of reduced thickness, composed of a mixture of cement, silica and cellulose fibers. The fiber-reinforced cement is formed by pressing and curing the mixture in an autoclave including sand, dimensional stability agents and additives or waterproofing agents incorporated at the surfaces of the layer exposed within the tile. The mixture has a fiber and cement content sufficiently high enough to allow for cutting and manipulating operations while joining to the natural stone part, and adjusted in such manner so as to combine elevated density, reduction of humidifying mobility and low bending resistance of the support layer joined to the plate of natural stone, and ensure the high stability of the joint. The adhesive is preferably a bicomponent epoxy resin, containing 5% of micro-nodules or micro-granules (which can be of glass or cellulose fibers) of average diameter 0.10 mm. Independent claims are also included for: 1) the production of the composite tile, comprising: a) cutting, out of a natural stone block, plates of thickness more than twice as large as the final thickness of natural stone layer b) joining firmly both faces of the cut plate with layers of support as claimed, using an adhesive and pressure, to form a unit comprising a natural stone layer sandwiched between two support layers, and curing the adhesive c) cutting the obtained unit into two, through the middle of the natural stone layer, to produce two composite tiles with natural stone faces and d) smoothing and polishing the natural stone faces and 2) the method of production of the natural stone/support layer units, comprising joining natural stone layers and support layers by means of curing the adhesive layers between them by heating (preferably to 50-60degreesC) for a pre-determined period (preferably for 12 minutes). There is optional stacking of units into piles, which are firmly secured together to prevent movement of the natural stone layers in relation to the support layers before the curing of the adhesive by e.g. strings of rapid contact glue, and/or protected by peripheral strings of e.g. wax (of height 3 mm and depth 1-1.2 mm) to prevent pressing out of adhesive during compression stage, using vertically applied pressure.
Patent ES-2187267-A1 (ES)
Title: Process for preparing rigid adsorbent materials involves use of carbon fibers, materials being used as adsorbents or supports of catalyzers
Inventor: MARBAN CALZON GREGORIO
IPC: C01B32/342
Filed: 2001-03-14
Abstract: The process for preparing rigid adsorbent materials involves the use of carbon fibers, the materials being used as adsorbents or supports of catalyzers. The most important input resides in the use of synthetic material with no commercial value (reject fibers from the manufacture of commercial synthetic fibers or synthetic fibers obtained by recycling worn textile products).  A simple carbonization process transforms the materials into carbon fibers for use in the manufacture of rigid, low density compositions.
Patent ES-2193836-A1 (ES)
Title: Disposable baby bottle
Inventor: RODRIGUEZ GONZALEZ JUAN MANUEL
IPC: A61J9/00
Filed: 2001-06-06
Abstract: Disposable baby bottle.Sterilized disposable baby bottle that is folded and vacuum wrapped in a bag (1).It includes a housing for the food that is flexible (2), contains grooves (13), and is hermetically sealed on the upper part to a disposable teat (3).Along its lower flat, stiff section (4), which is used to insert the food, it houses the pressure stopper (5). The stopper has pins (6) that slide over the hole and are pressure-inserted on the flat section (4) with grooves (7), hermetically locking and sealing the stopper so that the baby bottle cannot be reused. The stopper includes microperforations (8) that are sealed (9) and that can be easily unsealed to act with the external air to compensate for depression created by the suction.A plastic clip (10) is included for filling the bottle.
Patent ES-2204239-A1 (ES)
Title: Medio-ambiental applications of quartz, jade and malachite, for manufacture of articles for absorption of noxious radiation for health of living beings
Inventor: PARRA CARA MARIA CARMEN
IPC: H01Q17/00
Filed: 2001-06-06
Abstract: Medio-ambiental applications of quartz, jade and malachite and of mixtures amongst themselves and with clay are for manufacture of articles for absorption of noxious radiation for health of living beings. The articles can adopt very diverse forms in terms of their final purpose, being applicable domestically, industrially and technically.
Patent ES-2234428-A1 (ES)
Title: Compounds for the treatment of ocular dryness caused by photorefractive surgery
Inventor: BELMONTE MARTINEZ CARLOS
IPC: A61P27/02
Filed: 2003-12-09
Abstract: The blocking agents of the electrical activity of the damaged nerve endings of the neuroma can be used for the treatment of dryness of the ocular surface caused by photorefractive surgery, such as excimer laser photorefractive keratectomy or laser-assisted in situ keratomileusis. The administration of said blocking agents, which include antiepileptics, anticonvulsants, anti-arrhythmic drugs, tricyclic antidepressants and local anaesthetics and, in particular, include lidocaine, tocainide, phenytoin, carbamazepine, lamotrigine, mexiletine and pregabalin, effectively reduce the sensations of ocular dryness.
Patent ES-2265283-A1 (ES)
Title: Microporous absorbent for e.g. gas storage comprises a hydrothermally treated rare earth salt and terephthalic acid based mixture
Inventor: PERLES HERNAEZ JOSEFINA
IPC: C07C63/26
Filed: 2005-07-08
Abstract: The microporous absorbent for e.g. gas storage has hydrothermal treatment of a salt containing a rear-earth element or internal transition elements, and terephthalic acid or a salt of this. It can be employed as a molecular sieve, a catalyst and as an e.g. hydrogen storage agent.
Patent ES-2273599-A1 (ES)
Title: Selective a2a receptor antagonists for the treatment of auricular fibrillation
Inventor: FRANCO FERNANDEZ RAFAEL
IPC: A61K31/519
Filed: 2005-10-14
Abstract: Adenosine A 2A receptor antagonists are useful for the preparation of medicaments against atrial fibrillation in mammals, including humans. It has been found that the adenosine A 2A receptor is present in human atrial cardiomyocytes and participates in the pathological mechanisms underlying atrial fibrillation. An advantage of using A 2A antagonists over other agents known in the art is that the A 2A antagonists specifically target patients with atrial fibrillation.
Patent ES-2292325-A1 (ES)
Title: Method for producing stamped rollers for decorating facades, walls or interiors and product thus obtained
Inventor: GARCIA MURIES JOSE IGNACIO
IPC: B29C63/10
Filed: 2005-12-05
Abstract: The invention relates to a method for obtaining a mould (12) having internal walls which are provided with recesses (2) corresponding to different decorative patterns, in order to produce rollers (10) consisting of a sponge roller (4) which is covered with a layer of polyurethane (9), the surface of which includes decorative relief patterns (2a) for making incisions on a still-wet plastered surface using the stamped decorative patterns. The invention offers the considerable advantage that any decorative pattern can be made and formed on a plastered surface using a roller (10).
Patent ES-2301325-A1 (ES)
Title: Fuel injection apparatus module
Inventor: NAKAWAGA MITSUO
IPC: F02M37/00
Filed: 2003-09-24
Abstract: A fuel injection apparatus module where a fuel pump (11) and an injection pressure regulator (14) are integrally connected to an electric motor (10). The fuel pump (11) sends by pressure a fuel to an injector (13) by being driven by an output shaft (21a) of the electric motor (10), and the injection pressure regulator (14) regulates the pressure of the fuel injected by the fuel pump (11). An injector holder (47) for holding the injector (13) is integrally formed with a module body (40) connected to the fuel pump (11). A fuel passage (46) penetrating through each other the fuel pump (11), the injection pressure regulator (14), and the injector (13) is formed in the module body (40). This enables to eliminate a high-pressure fuel-guiding pipe between the injector and the fuel pump, remarkably reducing the cost of the fuel injection apparatus module.
Patent ES-2300184-A1 (ES)
Title: Arrangement for coupling a coupling pivot for a trimmable horizontal stabiliser to the tail fuselage of an aircraft
Inventor: GARCIA LUNA AGUSTIN
IPC: B64C1/26
Filed: 2006-04-28
Abstract: Device for coupling a coupling pivot for a trimmable horizontal stabilizer ( 1 b) to the tail fuselage ( 1 a) of an aircraft ( 1 ), with an inner plate ( 10 ), an outer plate ( 11 ) with first fastening holes ( 10 a, 11 a) and first passage holes ( 10 c) in the inner plate respectively facing second fastening holes ( 10 b, 11 b) and second passage holes ( 11 c) in the outer plate ( 11 ) for the passage of a coupling pivot ( 9 ) of the horizontal stabilizer ( 1 b) and with an upper lug ( 12 ) and a lower lug ( 13 ) respectively located above and below a cut-out ( 2 ) for the horizontal stabilizer ( 1 b). The lugs ( 12, 13 ) are integral with separate reinforced zones ( 14, 15 ) of the covering ( 1 f) in respective neighboring areas of the cut-out ( 2 ), in such a way that the plates ( 10, 11 ) between them clasp the respective reinforced zones ( 14, 15 ) in which the lugs ( 12, 13 ) are provided.
Patent ES-2326103-A1 (ES)
Title: Power unit supporting structure of scooter type vehicle
Inventor: HAYASHI HIDEKI
IPC: B62K11/10
Filed: 2006-09-18
Abstract: A power unit supporting structure for minimizing rotational vibration about the center of gravity of a power unit, and secondary vibration in the direction of a cylinder axis line of the power unit. The structure includes a link mechanism having a first frame side link swingably connected to a first pivot on the side of a rear frame, and first power unit side links swingably connected to a third pivot on a side of the power unit. The first frame side link and the first power unit side links are swingably connected by a second pivot. A first line segment connecting the first pivot and the second pivot is disposed approximately perpendicular to a cylinder axis line. A second line segment connecting the second pivot and the third pivot is approximately parallel to a third line segment connecting the third pivot and the center of gravity of the power unit.
Patent ES-2285960-A1 (ES)
Title: Method for transmission and reception of infra red signals across electrical line, involves obtaining primary signal from Infra red signal, where secondary signal or original digital signal is obtained after obtaining primary signal
Inventor: RIBAS XIRGO LLUIS
IPC: H02J13/00
Filed: 2007-04-16
Abstract: The method involves obtaining a primary signal from an infra red signal. A secondary signal or original digital signal is obtained after obtaining a primary signal. The secondary signal modulates a radio frequency signal, which is driven into a point of an electric line. The radio frequency signals are demodulated at other points of the electric line to extract original digital signal, which is processed by an electronic system. The modified digital signals are obtained by the processing of original digital signal, to generate and emit the infrared signals. Independent claims are also included for the following: (1) device for transmission and reception of infra red signals across an electrical line (2) system for transmission and reception of infra red signals across an electrical line.
Patent ES-2349817-A1 (ES)
Title: Simplified process for hot-rolling a structural steel with titanium as a microalloying element
Inventor: LOPEZ SERRANO VICTOR
IPC: C21D8/02
Filed: 2009-06-09
Abstract: Simplification of the hot-rolling process in a rolling train for structural steels containing Ti and N and with a Ti/N ratio of between 1 and 3, preferably close to 2. The recrystallized austenitic grain size is reduced very little between passes, since the starting point is a very small initial austenitic grain corresponding to the reheating temperature. The present invention proposes a smaller number of passes. The final ferritic grain would be refined by pre-hardening of the austenite, which is achieved by performing the last passes at temperatures close to Ar3, followed by immediate cooling after the passage through the rolling train, at a cooling rate of approximately 20 DEG C/s.
Patent ES-2372454-A1 (ES)
Title: Power storage module for railway vehicles
Inventor: NIEVA FATELA TXOMIN
IPC: H01G2/08
Filed: 2010-07-07
Abstract: Power storage module for railway vehicles, comprising multiple interconnected capacitors (1) with terminals (2) for establishing an electrical connection with a single connection plate (7) common to all the capacitors (1) and mechanical securing by means of a support plate (6) placed between the terminals (2) and the connection plate (7), the terminals (2) being oversized in such a way as to define a cooling channel between the support plate (6) and the capacitors (1), the connection plate (7) being insulated from said cooling channel by means of the support plate (6).
Patent ES-2396387-A1 (ES)
Title: Method for identifying carbonylated histones
Inventor: GARCIA GIMENEZ JOSE LUIS
IPC: C07K14/47
Filed: 2011-06-08
Abstract: The invention relates to a method for identifying carbonylated histones, which includes the electrophoretic separation of said histones in a gel that includes acrylamide, Triton X-100, glacial acetic acid and urea incubation of said gel with 2,4-dinitrophenylhydrazine (DNPH) electrophoretic separation of said histones in a gel that includes acrylamide, Tris- and sodium dodecyl sulfate the transfer of said histones from the preceding gel to an adsorbent membrane the detection of the presence of 2,4-dinitrophenyl (DNP) in said adsorbent membrane and identification of said carbonylated histones and the variants thereof. The invention likewise provides a kit for identifying carbonylated histones, which includes reagents for preparing a TAU gel, reagents for preparing a SDS-PAGE gel, 2,4-dinitrophenylhydrazine, a primary antibody specific to DNP and a secondary antibody marked vis-à-vis the primary antibody.
Patent RS-20130198-A1 (RS)
Title: Combined implement – plough-subsoiler
Inventor: RUŽIČIĆ LAZAR
IPC: A01B17/00
Filed: 2013-05-22
Abstract: Invention herewith described refers to the combined implement – plough-subsoiler which consists of the standard plough i.e. the moldboard (4) and the subsoiler working body (1) coupled by the connecting plate (3). The connection is achieved with three screws. On the connecting plate (3) there is allowed for the subsoiler working body (1) to be placed in several positions in order to determine the stipulated working depth in relation to the working depth of the moldboard