baber/WOPTO huggingface dataset:
Patent DE-69003216-T2 (DE)
Inventor: PUYOL MANUEL
IPC: A61P13/02
Filed: 1990-04-13
Granted: 1994-01-27
Abstract: The invention provides pharmaceutical compositions for use in the prevention or treatment of diseases and dysfunctions associated with pathological contraction of mesangial cells and other contractile cells responsive to angiotensin II and/or oxygen free radicals, comprising as active ingredient one or more somatostatin-active polypeptides. The somatostatins are particularly useful for the treatment or prevention of renal dysfunction. The invention also includes the use of somatostatin-active polypeptides for the preparation of such compositions and corresponding methods of treatment of humans and animals.
Patent DE-69003222-T2 (DE)
Inventor: HILLERS GUILLAUME EUGENE
IPC: E04B1/00
Filed: 1990-10-26
Granted: 1994-01-05
Abstract: A building structure consisting of a foundation set into the ground and a bearing, frontage and roof construction built thereon, wherein as foundation a solid walled supporting body (1) is wholly or partially sunk into the ground, wherein the bearing construction of the building to be placed thereon is a timber frame. In marshy or unstable ground the supporting body is of a size such that the weight of the displaced ground is greater than that of the foundation and building. Due to the timber frame construction, the construction with such a light weight can easily be placed on unstable ground.
Patent DE-69006052-T2 (DE)
Inventor: DELUCA HECTOR F
IPC: C07C401/00
Filed: 1990-03-09
Granted: 1994-05-05
Abstract: This invention provides a novel class of vitamin D-related compounds, namely the 1 alpha -hydroxy-19-nor-vitamin D analogs, as well as a general method for their chemical synthesis. The compounds exhibit pronounced activity in arresting the proliferation of undifferentiated cells, including malignant cells, and in inducing their differentiation, and thus represent novel therapeutic agents for the treatment of malignant and other diseases characterized by the proliferative grointh of undifferentiated cells. Formulations for therapeutic use and treatment methods are also provided.
Patent DE-69010022-T2 (DE)
Inventor: KAWASHIMA SHIGERU
IPC: A23L27/30
Filed: 1990-01-31
Granted: 1994-10-06
Abstract: The present invention is to solve a variety of problems relative to conventional lactitol crystals and relates to crystalline trihydrate of lactitol having a molecular formula C12H24O11.3H2O and a melting point of 52-56 DEG C, a solid crystalline mixture containing it and a process for their production.
Patent DE-69012245-T2 (DE)
Inventor: OHKUMA HIROAKI
IPC: C07D309/32
Filed: 1990-07-11
Granted: 1995-01-05
Abstract: The present invention relates to the antitumor antibiotic compound BU-3285T and its preparation. The compound is obtained by culturing a new strain of Chainia rosea and demonstrates both antitumor and antifungal activity. It also relates to the desulfated derivative of BU-3285T which is obtained by treatment of BU-3285T with sulfatase enzyme. BU-3285T desulfate possesses antitumor activity.
Patent DE-69031125-T2 (DE)
Inventor: RUNEMAN BO
IPC: A61F13/494
Filed: 1990-11-16
Granted: 1998-01-15
Abstract: The invention relates to a male incontinence guard intended for one-time use only and including an inner, liquid permeable casing layer (2), which is intended to lie closest to the body of the wearer in use, an outer liquid impermeable casing layer (3) and an absorbent pad (4) enclosed between the layers. According to the invention, a first part of the absorbent pad (4) intended to surround the user's scrotum, at least completely or partially, when the guard is in use, narrows towards the scrotum end (10) of the absorbent pad, i.e. towards the free end of the aforesaid first part of the pad; in that at least one elastic device (9) is attached in a prestretched state to the inner casing layer (2) and extends from the scrotum end (10) along each of the side edges (5a, 5b) of the pad over at least a part of the lengths of the side edges; and in that contraction of the elastic device or elastic devices form the prestretched state causes the first part of the absorbent body to take a curved shape so that, when the guard is used, the aforementioned part will be curved inwardly beneath the scrotum of the wearer.
Patent DE-69031148-T2 (DE)
Inventor: ARMSTRONG STEPHEN WADE
IPC: H03G11/00
Filed: 1990-05-18
Granted: 1997-12-04
Abstract: The clipping circuit has a voltage reference (3) and a transconductance (5) connected to a voltage input (Vin). The input is connected through the transconductance (5) to an output resistor (Rout). The voltage output is taken between the output resistor and the transconductance (5). The voltage reference (3) has a third current source (I3) feeding a diode connected transistor (Q1) and a resistor (R1). A second current source (I2) feeds into the resistor after the transistor. The base of the diode connected transistor (Q1) is connected to the voltage input. The transconductance (5) has a second transistor (Q2) whose base is connected to the voltage input, collector sinks current from a fourth current source and emitter feeds current to a resistor (R2). A first current source (I1) feeds. current to a third transistor (Q3) and to a current mirror. The base of the third transistor (Q3) is connected between the fourth current source (I4) and the collector of the second transistor (Q2). The current mirror draws current from the output resistor (Rout) and feeds current to between the emitter of the second transistor (Q2) and its associated resistor (R2). The transconductance creates a feed back loop such that a change in the first and second current sources creates a steady-state current drawn through the resistor (R2) that is one-half of the first current source current. The circuit produces symmetrical clipping of an input voltage signal at the voltage output.
Patent DE-69032882-T2 (DE)
Inventor: ISHIMITSU KEIICHI ODAWARA RESE
IPC: C07D213/74
Filed: 1990-10-04
Granted: 1999-06-10
Abstract: The present invention relates to a compound having formula (I) which has an excellent insecticidal activity, wherein R1 represents an optionally substituted 5-6 membered aromatic hetero ring containing nitrogen atom, except a non-substituted 2-pyridyl; X represents an optionally substituted C1-3 alkylene or alkylidene; R2 represents a hydrogen, a carbamoyl, a mono or di C1-5 alkyl carbamoyl, a thiocarbamoyl, a mono or di C1-5 alkylthiocarbamoyl, a sulfamoyl, a mono or di C1-5 alkylsulfamoyl, an optionally substituted C1-5 alkyl, an optionally substituted C2-5 alkenyl, an optionally substituted C2-5 alkynyl, an optionally substituted C3-8 cycloalkyl, an optionally substituted C3-8 cycloalkenyl, an optionally substituted aryl or -Y-R5; Y represents O, S(O)n, CO, CS or CO2; n represents 0, 1 or 2; R5 represents a hydrogen, an optionally substituted C1-5 alkyl, an optionally substituted C2-5 alkenyl, an optionally substituted C2-5 alkynyl, an optionally substituted C3-8 cycloalkyl, an optionally substituted C3-8 cycloalkenyl or an optionally substituted aryl; R3 represents a hydrogen, an optionally substituted C1-5 alkyl, an optionally substituted C2-5 alkenyl, an optionally substituted C2-5 alkynyl, an optionally substituted C3-8 cycloalkyl or an optionally substituted C3-8 cycloalkenyl; R4 represents a cyano or a nitro; and Z represents CH or N; or its salt.
Patent DE-69033889-T2 (DE)
Inventor: CHANCE RONALD EUGENE
IPC: C07K/
Filed: 1990-02-06
Granted: 2002-08-22
Abstract: Analogs of human insulin modified at position 29 of the B chain thereof and, optionally, at other positions, have modified physico-chemical and pharmacokinetic properties and are useful in the treatment of hyperglycemia. The insulin analogs are of the formula <IMAGE> or a pharmaceutically acceptable salt thereof, wherein A21 is alanine, asparagine, aspartic acid, glutamine, glutamic acid, glycine, threonine, or serine; B1 is phenylalanine, aspartic acid, or is absent; B2 is valine or may be absent when B1 is absent; B3 is asparagine or aspartic acid; B9 is serine or aspartic acid; B10 is histidine or aspartic acid; B27 is threonine or is absent; B28 is any amino acid, B29 is L-proline, D-proline, D-hydroxyproline, L-hydroxyproline, L-(N-methyllysine), D-lysine, L-(N-methylarginine) or D-arginine; B30 is alanine, threonine or is absent; Z is -OH, -NH2, -OCH3, or -OCH2CH3; X is Arg, Arg-Arg, Lys, Lys-Lys, Arg-Lys, Lys-Arg, or is absent; and Y may be present only when X is present and, if present, is Glu or an amino acid sequence which comprises all or a portion of the sequence <IMAGE>  and which begins at the N-terminus Glu of such sequence; provided that when A21 is asparagine, B1 is phenylalanine, B2 is valine, B3 is asparagine, B9 is serine, B10 is histidine, B27 is threonine, B28 is lysine, B29 is L-proline, B30 is threonine, X is absent and Y is absent, then Z is -NH2, -OCH3 or -OCH2CH3.
Patent DE-69100407-T2 (DE)
Inventor: POORE CYRIL
IPC: B65B61/20
Filed: 1991-01-24
Granted: 1994-02-03
Abstract: A container unit comprises an integrally formed container component (1) comprising a casing (20) and a closure (10), which includes a lid (11) intially sealed with an original seal (12). A separate bottom piece (30) for the container is permanently secured to the casing (20) of the container component containing the product, preferably by rotation-friction welding the bottom piece and the casing, both of which consist of polypropene. The component (1) is oriented with the closure (10) facing down and the product is poured in via the open end of the casing. The bottom piece is then placed in the open end of the container casing and rotation-friction welded to the casing. A partition (36) may be inserted in the casing to define a space for the product corresponding to the volume of the product. <IMAGE>
Patent DE-69101473-T2 (DE)
Inventor: HALTERS MARINUS ANTONIUS MARIA
IPC: F24C15/32
Filed: 1991-05-28
Granted: 1994-08-04
Abstract: Appliance for the preparation of meat or similar products, comprising an outer (3) and an inner (4) casing, a fan (5) for circulating cooling air in the space between the inner and the outer casing, a separate space in the inner casing with heating elements (6) and an air circulation fan (7) set up in it, which space is in communication by means of air admission openings with the actual treatment space for the product, and in which space a holder for the product to be treated, such as a rotating spit (8), grille or the like, is set up, while drive means for the fans (15), the rotating spit (9) and the like are set up in the space between the inner and the outer casing. In the appliance the drive means of the air circulation fan and the heating elements are controllable; the inside space of the inner casing can be placed in communicaton with the environment by means of an air inlet (11) and outlet (10); and the space formed by the inner casing is shut off substantially leakproof from the environment. All parts are connected to a control assembly (2). <IMAGE>
Patent DE-69101519-T2 (DE)
Inventor: HAKALA JAAKKO
IPC: F16M5/00
Filed: 1991-05-27
Granted: 1994-08-18
Abstract: The invention concerns a method for making the foundation slabs of a paper machine. In the method, for concreting of the base beam (10), reinforcement strands (11) are fitted inside a mould (M). Before filling-concreting of the mould (M), the base slab (14) is installed in connection with the reinforcement strands (11) and preferably on support of said strands. In the method, after the slab (14) has been installed as sufficiently plane (+/- 5 mm) and with its face horizontal, the filling-concreting of the base slab is carried out. Upon drying of the concrete cast, the final tightening of the bolts (13) of the base slab (14) is carried out. The ultimate machining of the base slab is carried out on site in the mill space by passing a machining device (20) on support of guides (21), which have been adjusted to a horizontal level, along the slab (14) faces. <IMAGE>   <IMAGE>
Patent DE-69102956-T2 (DE)
Inventor: WEISEMANN CLAUS DR
IPC: A23L5/20
Filed: 1991-08-19
Granted: 1995-01-19
Abstract: In a process for deacidifying and improving the flavor of socalled secondary extracts obtained in the production of instant coffees, the secondary extracts are pumped over alkaline molecular sieves and are therewith completely or partially liberated from acids and flavor-impeding organic compounds.
Patent DE-69117646-T2 (DE)
Inventor: VERHELST GABRIEL
IPC: C08G18/32
Filed: 1991-09-10
Granted: 1996-08-01
Abstract: A method for preparing a polyurethane/polyurea flexible foam which comprises reacting :     A. an organic prepolymer-containing polyisocyanate composition of NCO content of from 2 to 15% by weight; B. an isocyanate reactive component in which the isocyanate-reactive species comprises at least 40% by weight of water and at least one chain extender of molecular weight below 1000 which is selected from those having at least two amine groups of which at least one is directly attached to a cyclic hydrocarbon residue and from diamino polyols. r
Patent DE-69126163-T2 (DE)
Inventor: KISHIMOTO JIRO
IPC: C12R1/19
Filed: 1991-03-26
Granted: 1997-11-27
Abstract: A mutant strain having a glucose consumption rate is at most 1/4 that of wild type strains is provided. The mutant strain belongs to Escherichia, Bacillus, Pseudomonas, or Serratia; has a glucose consumption rate of at most one fourth that of the corresponding wild type strain, and the feedback repression by biotin is removed. Further, a process for producing biotins using this mutant strain is provided.
Patent DE-69128651-T2 (DE)
Inventor: BECKER KURT
IPC: C22C47/08
Filed: 1991-05-09
Granted: 1998-04-23
Abstract: The present invention relates to a novel process for forming metal matrix composite bodies. Particularly, an infiltration enhancer and/or an infiltration enhancer precursor and/or an infiltrating atmosphere are in communication with a filler material or a preform, at least at some point during the process, which permits molten matrix metal to spontaneously infiltrate the filler material or preform. Such spontaneous infiltration occurs without the requirement for the application of any pressure or vacuum. The molten matrix metal is provided in a unique manner which enhances the spontaneous infiltration process.
Patent DE-69128793-T2 (DE)
Inventor: JAERVINEN PEKKA
IPC: B66F9/06
Filed: 1991-07-01
Granted: 1998-06-04
Abstract: A lifting device (1) for moving of a load (12) on one plane, changing of the moving plane and continuation of the moving on the second plane. The lifting device (19) comprises a body (2), a thereto supported, as to its vertical position by means of a lifting mechanism (4) guided sliding carrier (3) with forks (14), optional moving wheels (5), wheeled supporting arms (9), which while moving from one plane onto another can, guided by a slide element (10) connected to the body (2), be pulled substantially to the side of the body (2) that is opposite the load (12).
Patent DE-69130256-T2 (DE)
Inventor: COHEN RICHARD
IPC: A61B5/0452
Filed: 1991-10-23
Granted: 1999-04-29
Abstract: An array of electrodes is applied to an internal or external surface of a biological system such as a human being. The electrodes generate signals which are processed to compute a surface differential of the surface potential at a multiplicity of spatial locations within a given time epoch. The signal processing is repeated for multiple sequential time epochs and an image is constructed from the surface differential of the surface potential for each time epoch. Thereafter, the sequential images corresponding to sequential time epochs are displayed. The two-dimensional image changes as the distribution of bioelectric sources evolves so as to provide a motion picture of electrical activity.
Patent DE-69209360-T2 (DE)
Inventor: TAN HONG SHENG
IPC: A01N25/02
Filed: 1992-05-12
Granted: 1996-09-05
Abstract: An oil in water emulsion is provided which comprises a suitable emulsifier, optionally a suitable co-emulsifier, and at least one suitable antifungal agent, whereby the antifungal agent is in suspension in the waterphase.
Patent DE-69229827-T2 (DE)
Inventor: DASGUPTA PURNENDU
IPC: B01D57/02
Filed: 1992-09-23
Granted: 1999-12-16
Abstract: Improved capillary electrophoresis apparatus of the type that generally includes a capillary tube, the capillary tube having a sample inlet end and an outlet end, a first electrode in electrical communication with the inlet end of the capillary tube, a second electrode in electrical communication with the outlet end of the capillary tube and a high voltage power supply in electrical communication with the first and second electrodes. The improvement is to connect a miniature Ion Chromatography membrane suppressor to the outlet end of the capillary tube, to connect a conductivity detector to the membrane suppressor and to place the second electrode in the regenerant compartment of the membrane suppressor. The method embodiment of the invention for anion analysis includes the steps of: (a) separating anions of interest by capillary electrophoresis in a buffer solution; (b) exchanging cations of the buffer for regenerant cations using an ion chromatography membrane suppressor to reduce the electrical conductivity of the buffer to produce a suppressed buffer; and (c) measuring the electrical conductivity of the suppressed buffer to determine the separated anions. Similarly, the method embodiment of the invention for cation analysis includes the steps of: (a) separating cations of interest by capillary electrophoresis in a buffer solution; (b) exchanging anions of the buffer for regenerant anions using a stationary means for exchanging anions thereby reducing the electrical conductivity of the buffer to produce a suppressed buffer; and (c) measuring the electrical conductivity of the suppressed buffer to determine the separated cations.
Patent DE-69232498-T2 (DE)
Inventor: BROEKAERT FRANS
IPC: C12N15/05
Filed: 1992-06-03
Granted: 2002-10-10
Abstract: Biocidal proteins isolated from Amaranthus have been characterised. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find commercial application as antifungal or antibacterial agents; transgenic plants will show increased disease resistance.
Patent DE-69313897-T2 (DE)
Inventor: CARLEN BO
IPC: B65G17/46
Filed: 1993-03-15
Granted: 1998-02-12
Abstract: A gripper conveyor includes a moving conveyor chain (1) which is provided with grippers (3). Each of the grippers (3) includes a fixed clamping jaw (31), a pivotal clamping jaw (33) and a spring (36) which biases the grippers (3) towards their closed positions. The conveyor includes an opening means (40) which functions to open selected grippers (3) while the conveyor chain moves, and the pivotal clamping jaw (33) of respective grippers (3) has a manouvering arm (37) which is activated by the opening means (40). The movable clamping jaw (33) is pivotally mounted on a shaft (32) for limited, free pivotal movement in the pivoting direction. Because the centre of gravity (331) of the movable clamping jaw (33) is distanced from the shaft (32) the movable jaw (33) is able to swing downwardly and outwardly into abutment with the support surface (N1, N11) on which the article, for instance a newspaper, to be gripped lies. Optionally, the outward swinging movement of the movable jaw (33) is assisted by a spring (35). <IMAGE>
Patent DE-69320618-T2 (DE)
Inventor: ZUIDEMA HETTE
IPC: B01F7/02
Filed: 1993-12-14
Granted: 1999-05-12
Abstract: Method for mixing granulates, powders and liquids in a continuous process, whereby the material is placed in a mixing housing (2) and is mixed therein with the aid of a rotor (6,7) equipped with mixing arms (9,12,13). The material is thereby moved to and fro many times during one rotation of the rotor, towards the rotor axis and away from it. For that purpose the device with which the method is implemented has longitudinal stators, mounted principally in the axial direction of the rotor, between which the mixing arms move when in operation. The mixing housing consists preferably of two chambers situated behind one another seen in the direction of the axis of the rotor and separated from one another by the rotor disk. The material which is to be mixed enters the housing in the first chamber, where it is undergoes a preliminary mix, then flows into the second chamber and is mixed further there. <IMAGE>
Patent DE-69325375-T2 (DE)
Inventor: WALTER HILGER
IPC: F02C7/00
Filed: 1993-06-16
Granted: 1999-10-21
Abstract: A process and a computer implemented system for controlling an axial compressor through measurement of pressure fluctuations of the turbulent fluid layer in the region of the compressor housing in at least one stage of the compressor by means of at least one pressure sensing device sensitive to differential pressure fluctuations affecting the blades at the characteristic frequency of the stage. The process and computer implemented system use a characteristic peak which emerges under load in a smoothed frequency signal derived from a transform of the pressure measurement to achieve optimal efficiency while, at the same time, avoiding destructive surge and stall conditions in the compressor.
Patent DE-69329838-T2 (DE)
Inventor: AMICI ROBERT MARK
IPC: C08L25/02
Filed: 1993-04-21
Granted: 2001-08-16
Abstract: Polymer containing a high percentage of vinyl alcohol units may be blended or formed into a segmented polymer with alkyl methacrylate unsaturated organic acid copolymer and processed into sheet, film, fiber and other objects which exhibit an useful balance of barrier and strength properties.
Patent DE-69333074-T2 (DE)
Inventor: COCHRAN D
IPC: C12N7/00
Filed: 1993-08-06
Granted: 2004-04-15
Abstract: The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
Patent DE-69402558-T2 (DE)
Inventor: OFOSU-ASANTE KOFI
IPC: C11D1/722
Filed: 1994-08-09
Granted: 1997-11-06
Abstract: Concentrated Liquid or gel dishwashing detergent compositions containing high active levels of surfactant, calcium ions and disulfonate surfactant are disclosed. The compositions exhibit improved stability as well as providing good cleaning and grease removal benefits. Particularly preferred compositions also contain simple sugars.
Patent DE-69417554-T2 (DE)
Inventor: NYSTROEM JAN-ERIK
IPC: C07C279/22
Filed: 1994-06-01
Granted: 1999-09-02
Abstract: PCT No. PCT/SE94/00517 Sec. 371 Date Jun. 28, 1994 Sec. 102(e) Date Jun. 28, 1994 PCT Filed Jun. 1, 1994 PCT Pub. No. WO94/29269 PCT Pub. Date Dec. 22, 1994A process for the production of guanidino protected  omega -aminoalkyl guanidines comprising reacting a diamine selectively at one amino group with an alkoxycarbonyl or aralkoxycarbonyl protected electrophilic guanylation reagent. The process of the invention is general and may be performed efficiently in one step yielding a product with high purity and in useful yields. The invention further refers to some compounds that are novel per se and to some novel compounds useful in the process of the invention.