baber/WOPTO huggingface dataset:
Patent CA-3118267-A1 (CA)
Title: Orbitrap for single particle mass spectrometry
Inventor: JARROLD MARTIN F
IPC: H01J49/00
Filed: 2019-01-11
Abstract: An orbitrap may include elongated inner and outer electrodes, wherein the inner and outer electrodes each define two axially spaced apart electrode halves with a central transverse plane extending through the electrodes also passing between both sets of electrode halves, a cavity defined radially about and axially along the inner electrode between the two inner electrode halves and the two outer electrode halves, means for establishing an electric field configured to trap an ion in the cavity and to cause the trapped ion to rotate about, and oscillate axially along, the inner electrode, wherein the rotating and oscillating ion induces charges on the inner and outer electrode halves, and charge detection circuitry configured to detect the charges induced on the inner and on outer electrode halves, and to combine the detected charges for each oscillation to produce a measured ion charge signal.
Patent CA-3122456-A1 (CA)
Inventor: NUR ISRAEL
IPC: A61K38/00
Filed: 2019-12-11
Abstract: La présente invention concerne des kits constitués d'un premier récipient renfermant une solution d'un composant comprenant du fibrinogène qui contient du fibrinogène à raison d'une concentration d'environ 5 mg/ml à environ 30 mg/ml, et présentant une concentration en protéines totales variant entre environ 15 mg/ml et environ 40 mg/ml ; et un second récipient renfermant une solution d'un composant contenant de la thrombine. L'invention concerne en outre des mélanges constitués de fibrinogène et de thrombine, d'ions calcium et d'albumine, le mélange contenant des protéines, à raison, au total, d'environ 2,5 mg/ml à environ 30 mg/ml, du fibrinogène à raison d'environ 50 % à environ 80 % des protéines totales, et de l'albumine à raison de plus de 0,65 mg/ml à environ 3 mg/ml. L'invention concerne en outre des procédés de prévention ou de réduction de l'adhérence tissulaire, et des matériaux hydrogel constitués de fibrine.
Patent CA-3124758-A1 (CA)
Title: Compounds comprising cleavable linker and uses thereof
Inventor: PARK TAEKYO
IPC: A61P35/00
Filed: 2020-01-03
Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.
Patent CA-3125115-A1 (CA)
Title: Improved uplink performance for bearers
Inventor: KRISHNAN REMAN
IPC: H04W28/18
Filed: 2019-12-12
Abstract: A system and method for detecting and correcting uplink-only problems is disclosed. The system comprises one or more of the following modules: uplink problem detection module, maximum permissible limit module, and uplink improvement calculation and actions module. The uplink problem detection module detects uplink-only problems using values of one or more parameters related to bearer performance. For instance, the uplink problem detection module continuously monitors the uplink performance by checking uplink transmission error and when a threshold is crossed, declares an uplink problem. The maximum permissible limit module limits the actions by uplink improvement calculation and actions module so that other parts in the system are not negatively affected. The uplink improvement calculation and actions module determines and performs the actions to improve the uplink transmission error situation detected by the uplink problem detection module.
Patent CA-3127617-A1 (CA)
Title: Self-aligning, multi-stab connections for managed pressure drilling between rig and riser components
Inventor: ZIEGLER ROBERT
IPC: E21B19/00
Filed: 2020-02-21
Abstract: A riser (20) extending from a floating rig (12) includes one or more flow control devices (30, 32, 34) having at least one flow connection (90a) and having at least one control connection (90b). A riser manifold (100a) is disposed on the riser above the one or more flow control devices and has a first mechanical connector (106), a first flow coupling, and a first control coupling. A rig manifold (150a, b) can be manipulated by an arm to couple in an automated manner to the riser manifold (100a, b) when running the riser from the rig. The rig manifold (150a, b) has a second mechanical connector (156) that mechanically connects to the first mechanical connector of the riser manifold. Additionally, the rig manifold has a second flow coupling mating with the first flow coupling of the riser manifold for conducting flow, and has a second control coupling mating with the first control coupling of the riser manifold for conducting control.
Patent CA-3130992-A1 (CA)
Title: Foam-plastic protector
Inventor: BELAND JEAN-FRANCOIS
IPC: A63B71/08
Filed: 2021-09-15
Abstract: A foam-plastic protector includes a foam insert having a front surface and a rear surface. A plastic sleeve is harder than the foam insert and has a base and an overlapping portion spaced from the base to define a gap. The foam insert is removably received against the base and inter-locked with the plastic sleeve. A covered portion of the foam insert is positioned within the gap and covered by the overlapping portion of the plastic sleeve. A remainder of the foam insert is exposed. A protective sport padding and a method of assembling same are also disclosed. The foam insert may be fixedly attached to the protective sport padding.
Patent CA-3132926-A1 (CA)
Title: Device for holding and releasing an object and corresponding methods
Inventor: RICHART OLIVIER
IPC: A61B50/20
Filed: 2020-05-12
Abstract: The invention relates to a device (1) for retaining and releasing an object (7, 8), which device comprises a main body (10) having a housing for at least partially accommodating the object and an outlet (107) for enabling at least part of the object to be released, a cover (20) which is movable between a closed position preventing access to the outlet (107) and an open position providing access to the outlet (107), and a stop mechanism (3) which is configured to be movable into different positions relative to the main body (10) in the direction of the outlet (107) of the main body (10), but blocked in the opposite direction, so as to enable the stop mechanism (3) to be brought into contact with or close to the object (7, 8) while preventing a return movement of the stop mechanism (3). The invention also relates to a production method and corresponding release methods.
Patent CA-3133740-A1 (CA)
Inventor: ATTRAMADAL HAVARD
IPC: A61K38/18
Filed: 2020-03-20
Abstract: The present invention relates to recombinant proteins having an amino acid sequence corresponding to or related to the thrombospondin type 1 repeat homology domain of a member of the CCN family proteins and the use thereof. Furthermore, the present invention relates to fusion proteins comprising an amino acid sequence corresponding to or related to the thrombospondin type 1 repeat homology domain of a member of the CCN family proteins combined with a fusion partner and optionally a linker region. Also, novel protease resistant Fc-fragments are disclosed herein.
Patent CA-3135539-A1 (CA)
Inventor: HORDEAUX JULIETTE
IPC: A61K9/00
Filed: 2020-05-02
Abstract: Provided is a recombinant adeno-associated virus (rAAV) having an AAVhu68 capsid and a vector genome which comprises a nucleic acid sequence encoding a functional human arylsulfatase A (ARSA). Also provided are a production system useful for producing the rAAV, a pharmaceutical composition comprising the rAAV, and a method of treating a subject having metachromatic leukodystrophy, or ameliorating symptoms of metachromatic leukodystrophy, or delaying progression of metachromatic leukodystrophy via administrating an effective amount of the rAAV to a subject in need thereof.
Patent CA-3137068-A1 (CA)
Title: Efficient message transmission and loop avoidance in an rpl network
Inventor: SABHARWAL ANKUSH
IPC: H04W40/24
Filed: 2020-04-09
Abstract: In some implementations, formation of loops between nodes in an RPL network may be avoided. A node that receives a neighbor-discovery message may determine, based on a parent-child status, whether the message was received from a parent of the node. If the neighbor-discovery message was received from the parent, the node may transmit an error code to the parent. In addition, the node may determine, based on node reliability rankings, whether the neighbor-discovery message was received from a node with high reliability, such as a potential grandparent node. If the neighbor-discovery message was received from a high-reliability node, the node may transmit an error code to the high-reliability node. Furthermore, the node may reduce network traffic by withholding a neighbor-detection message from a child node. The node may transmit a response to neighbor-detection messages received from the child node.
Patent CA-3138467-A1 (CA)
Title: Composition for prevention or treatment of hair loss including hapln1
Inventor: KIM DAE KYONG
IPC: A61Q7/00
Filed: 2020-04-29
Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of hair loss, the composition comprising hyaluronan and proteoglycan link protein 1 (HAPLN1) as an active ingredient. When administered, the HAPLN1 protein of the present invention promotes proliferation of hair germinal matrix cells through the Ras-ERK1/2 signaling pathway activated by TGF-ß protein, thereby growing hair.
Patent CA-3141065-A1 (CA)
Inventor: WEST CONNOR LEE
IPC: B65D90/48
Filed: 2020-07-22
Abstract: A safety door latch system is presented for a grain bin having a door frame. An inner door is connected to the door frame that is configured to move between an open position and a closed position. An outer door is connected to the door frame and is configured to move between an open position and a closed position. A safety mechanism is connected to the door frame and is configured to move between an open position and a closed position. When the inner door frame is moved to a closed position, a portion of the inner door engages the safety mechanism thereby causing the safety mechanism to move to the closed position. When the safety mechanism is in the closed position, the outer door may be latched to the safety mechanism. When the safety mechanism is in the open position, the outer door cannot latch to the safety mechanism.
Patent CA-3141073-A1 (CA)
Title: Structures diffractives a l'interieur de substrats polymeres, leur fabrication et leur utilisation
Inventor: MACPHERSON CHARLES DOUGLAS
IPC: B42D25/328
Filed: 2020-06-25
Abstract: La présente invention concerne des dispositifs optiques appropriés en tant que dispositifs de sécurité pour une authentification de documents, qui comprennent au moins un réseau bidimensionnel de pistes allongées modifiées par laser s'étendant à l'intérieur d'un substrat de document qui présentent un indice de réfraction optique distinct par rapport à celui du substrat non modifié, qui peuvent présenter d'excellents effets de diffraction. La présente invention porte également sur l'utilisation de tels dispositifs pour une authentification de documents et sur des procédés pour leur production.
Patent CA-3141579-A1 (CA)
Title: Crackling hand sanitizer formulations and associated methods
Inventor: PATEL NIRALI
IPC: C11D11/00
Filed: 2021-12-09
Abstract: A composition and associated methods of manufacture for a new type of hand sanitizer that has a "crackling" effect when the user rubs it between their hands. Crackling hand sanitizer formulations promote hand sanitizing because of the interactive user experience provided during application and use of the fommlations. A hand sanitizer concentrate solution mixed with a propellant and thickening agent results in a formulation that provides a crackling effect when applied to the hands by a user. The "crackling effect" is a physical reaction when the formulation is in contact with the user's skin, in which the propellant evaporates, causing a crackling sound while also providing a tingling or effervescent feeling on the skin.
Patent CA-3142603-A1 (CA)
Inventor: COHEN YARIV
IPC: C05B11/00
Filed: 2020-06-11
Abstract: A method for decomposing struvite comprises dissolving (S10) of a feed material comprising struvite in a mineral acid. Thereby a solution having an acid pH is formed. Magnesium is removed (S30) from the solution. The removing of magnesium comprises increasing (S32) a pH of the solution to a pH in the range of 4.5 to 6, precipitating (S34) magnesium compounds that do not comprise ammonium, and separating (S36) the precipitated magnesium compounds from the solution. Thereby, the solution, after the removing of magnesium, comprises an ammonium salt of the mineral acid. An arrangement for performing such a method is also disclosed. Also, a method and arrangement for recovering at least nitrogen from waste material, based on the decomposing of struvite are disclosed.
Patent CA-3143939-A1 (CA)
Title: Thermophysical float glass process
Inventor: MASTEN JAMES WILLIAM
IPC: C03B18/02
Filed: 2021-12-23
Abstract: A novel apparatus and method for producing flat glass by floating molten glass on liquid tin, significantly improving the efficiency of heating the tin and reducing or eliminating the need to anneal by eliminating the stress introduced by pulling the glass across the tin bath. The apparatus directly heats and melts the tin by exposure to high-intensity infrared energy through surfaces of the tin-containing tub, said tub made from a material that is transmissive at selected infrared wavelengths.
Patent CA-3144430-A1 (CA)
Inventor: ZHANG SHIJUN
IPC: C07C211/04
Filed: 2020-07-15
Abstract: Des composés d'échafaudage sont utilisés pour concevoir des composés à petite molécule et des études de relation structure-activité pour identifier des inhibiteurs d'inflammation. Des procédés comprennent des compositions pharmaceutiques des composés à petite molécule pour inhiber, prévenir et traiter des maladies et des états associés à une inflammation, y compris la sclérose en plaques, la maladie d'Alzheimer, l'infarctus aigu du myocarde, une lésion cérébrale traumatique et des maladies auto-inflammatoires.
Patent CA-3146976-A1 (CA)
Title: Traitement de maladies par expression d'une enzyme a activite desoxyribonuclease (dnase)
Inventor: GENKIN DMITRY DMITRIEVICH
IPC: A61P1/16
Filed: 2020-07-10
Abstract: L'invention concerne l'administration et/ou l'expression d'une enzyme qui a une activité désoxyribonucléase (DNase) spécifique du foie, du système nerveux et/ou de l'intestin, ce qui permet d'améliorer la libération d'ADN acellulaire (cfDNA) utile pour le traitement de diverses maladies et affections, y compris le cancer et la neurodégénérescence.
Patent CA-3151045-A1 (CA)
Inventor: LEMMERS JAAP GERARDUS HENRICUS
IPC: A61K31/437
Filed: 2020-10-16
Abstract: La présente invention concerne des composés de formule I et leurs sels pharmaceutiquement acceptables. Ces composés peuvent être utilisés en tant que modulateurs du récepteur alpha associé aux oestrogènes (ERR?) et ont une utilité dans le traitement de maladies ou d'affections médiées par ERR?. (I)
Patent CA-3151922-A1 (CA)
Inventor: RAMASUNDARAM BHARANIKUMAR
IPC: G01G3/12
Filed: 2020-08-21
Abstract: According to some embodiments, a load cell for determining a weight of a large object comprises a base plate comprising at least one recessed opening, a bulk metallic glass plug disposed in the at least one recessed opening of the base plate, and a top plate positioned above the base plate. A portion of the top plate is supported by the bulk metallic glass plug. The load cell further comprises a micro strain sensor coupled to the bulk metallic glass plug. The micro strain sensor is operable to determine a change in micro strain on the bulk metallic glass plug. The bulk metallic glass plug extends to a height where the top plate does not contact the base plate.
Patent CA-3152762-A1 (CA)
Title: Submucosal bioresorbable drug eluting platform
Inventor: NGO TU DUC
IPC: A61L31/16
Filed: 2020-08-28
Abstract: Described here are systems and methods for delivering an active agent to target tissues of the ear, nose, or throat using a drug delivery platform having the therapeutic drug embedded as part of the drug delivery platform. The drug delivery platform is implanted into a target tissue, and the active agent elutes out of the body of the drug delivery platform for a target period of time, delivering a therapeutic dose of the drug for that period of time. The duration of therapy for an implant into a sinus tissue can be from 3 to 12 months, or longer, thereby providing relief for the full duration of an allergy season. Moreover, the duration of therapy can provide relief to individuals with chronic paranasal sinus condition symptoms for a period of time longer than presently available therapies, thus allowing for only semi-annual or annual applications of the therapy.
Patent CA-3154952-A1 (CA)
Inventor: DETRAVERSAY MAXIME
IPC: A01K5/02
Filed: 2020-12-11
Abstract: La présente divulgation concerne d'une manière générale l'alimentation animale et, en particulier, un procédé permettant de faire fonctionner un robot d'alimentation autonome (1) au niveau d'une table d'alimentation dans une zone d'élevage (30). Selon un premier aspect, la divulgation concerne un procédé permettant de faire fonctionner un robot d'alimentation autonome (1) au niveau d'une table d'alimentation dans une zone d'élevage (30), une ou plusieurs caméras (32) étant disposées de manière fixe dans la zone d'élevage afin de surveiller la table d'alimentation, le procédé consistant à obtenir (S1) une ou plusieurs images capturées à l'aide de la ou des caméras disposées de manière fixe (32) et indiquant une distribution d'aliment (3) sur la table d'alimentation et à commander (S4) le fonctionnement du robot d'alimentation autonome (1) sur la base de la distribution de l'aliment (3) indiquée par l'image ou les images. La divulgation concerne également des circuits de commande (10) permettant de faire fonctionner un robot d'alimentation autonome (1) et un programme informatique permettant de mettre en ?uvre le procédé.
Patent CA-3160061-A1 (CA)
Inventor: RAZEEM MOHAMMED
IPC: C08J11/24
Filed: 2020-11-13
Abstract: A method of forming a multimodal Polyalkylene Terephthalate (PAT) can include: providing a feed of a low molecular weight (LMW) PAT, the LMW PAT having a low average molecular weight; providing a feed of high molecular weight (HMW) PAT, the HMW PAT having a high average molecular weight, wherein the low average molecular weight is lower than the high average molecular weight; mixing the feed of LMW PAT with the feed of HMW PAT in a mixer to form a multimodal PAT; and providing the multimodal PAT as output. The multimodal PAT can include: a low average molecular weight of a low molecular weight (LMW) PAT; and a high average molecular weight of a high molecular weight (HMW) PAT mixed with the LMW PAT to form the multimodal PAT, wherein the multimodal PAT is devoid of talc.
Patent CA-3161351-A1 (CA)
Inventor: WANG ZHENYU
IPC: C07D401/12
Filed: 2020-12-09
Abstract: L'invention concerne un composé tel que représenté par la formule (I) ou un sel pharmaceutiquement acceptable, un stéréoisomère, un dérivé isotopique ou un promédicament de celui-ci. Le composé présente une excellente activité en tant qu'inhibiteur de la kinase 9 dépendante de la cycline (CDK9) pour le traitement de maladies hyperprolifératives. La recherche expérimentale sur l'inhibition in vitro de la prolifération cellulaire et la suppression in vivo de tumeurs montre que de tels composés ont un effet inhibiteur relativement puissant sur le MV4; des modèles de cellules et de tumeurs in vivo, et ont une bonne sélectivité et une faible toxicité et peu d'effets secondaires, ce qui leur confère une bonne valeur clinique en tant que nouveaux médicaments antitumoraux.
Patent CA-3161786-A1 (CA)
Inventor: LIU ZHIJUN
IPC: B62B5/06
Filed: 2021-08-03
Abstract: A new type of dump truck includes a vehicle frame (300) and a vehicle body (500) hinged on the vehicle frame (300), a front wheel installation shaft (620) and a rear wheel installation shaft (610) respectively arranged on front and rear ends of the vehicle frame (300), and wheels (600) installed on the front wheel installation shaft (620) and the rear wheel installation shaft (610), a connecting plate (314) fixedly installed below the rear end of the vehicle body (500), and a body rotation shaft (510) fixed below the connecting plate (314), the connecting plate (314) and the vehicle frame (300) are rotatably connected through the body rotation shaft (510), and the body rotation shaft (510) is arranged directly above the rear wheel installation shaft (610).
Patent CA-3164007-A1 (CA)
Title: Ensemble de coupe pour machine d'exploitation miniere
Inventor: PUCHER FRIEDRICH
IPC: E21C27/22
Filed: 2020-01-20
Abstract: L'invention concerne un ensemble de coupe (1) pour une machine d'exploitation minière (2), ledit ensemble (1) comprenant un moyeu central (3) comprenant au moins un bras (4) s'étendant radialement vers l'extérieur à partir dudit moyeu (3), le bras (4) étant pourvu d'au moins un support de moyens de coupe (5) fixé mobile sur le bras (4) pour un mouvement radial le long du bras (4). Le bras (4) est pourvu d'un actionneur primaire (6) configuré pour commander la position radiale du support de moyens de coupe (5). L'ensemble de coupe (1) comprend également un moyen de verrouillage (7) mobile entre une position déverrouillée et une position verrouillée, le moyen de verrouillage (7), dans sa position verrouillée, verrouillant le support de moyens de coupe (5) sur le bras (4), de sorte qu'un mouvement radial dudit support (5) soit empêché. Le moyen de verrouillage (7) comprend au moins un élément de verrouillage (8) disposé sur le bras (4) de sorte que l'élément de verrouillage (8) soit mobile entre une position allongée et une position rétractée, l'élément de verrouillage (8), dans sa position allongée, s'étendant pour venir en prise avec le support de moyens de coupe (5) de sorte que le mouvement dudit support (5) soit empêché.
Patent CA-3165634-A1 (CA)
Inventor: ASIRVATHAM EDWARD
IPC: H01L31/0236
Filed: 2020-12-18
Abstract: Des agents de pré-texturation, des agents de gravure et des agents de décapage de résine photosensible peuvent être formulés pour comprendre un ou plusieurs tensioactifs, d'une ou de plusieurs classes de tensioactifs, tels que des dérivés siloxanes d'acides aminés qui ont des propriétés tensioactives.
Patent CA-3166664-A1 (CA)
Title: Augmented semiconductor lasers with spontaneous emissions blockage
Inventor: FROUGIER JULIEN
IPC: H01S5/183
Filed: 2021-01-28
Abstract: A device and a method to produce an augmented-laser (ATLAS) comprising a bi-stable resistive system (BRS) integrated in series with a semiconductor laser. The laser exhibits reduction/inhibition of the Spontaneous Emission (SE) below lasing threshold by leveraging the abrupt resistance switch of the BRS. The laser system comprises a semiconductor laser and a BRS operating as a reversible switch. The BRS operates in a high resistive state in which a semiconductor laser is below a lasing threshold and emitting in a reduced spontaneous emission regime, and a low resistive state in which a semiconductor laser is above or equal to a lasing threshold and emitting in a stimulated emission regime. The BRS operating as a reversible switch is electrically connected in series across two independent chips or on a single wafer. The BRS is formed using insulator-to-metal transition (IMT) materials or is formed using threshold-switching selectors (TSS).