baber/WOPTO huggingface dataset:
Patent CA-2450274-C (CA)
Title: Benzoxazepine derivatives and their use as ampa receptor stimulators
Inventor: GROVE SIMON JAMES ANTHONY
IPC: A61P25/00
Filed: 2002-06-05
Granted: 2010-12-21
Abstract: The present invention relates to benzoxazepine derivative having the general formula I, wherein X represents CO or SO2; R1, R2, R3 and R4 are independently selected from H, (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, halogen, nitro, cyano, NR8R9, NR8COR10, and CONR8R9, R5, R6 and R7 are independently H or (C1-4)alkyl; R8 and R9 are independently H or (C1-4)alkyl; or R8 and R9 form together with the nitrogen atom to which they are bound a 5-or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR11; R10 is (C1-4)alkyl; R11 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives, and to the use of these benzoxazepine derivatives in the treatment of neurological diseases and psychiatric disorders which are responsive to enhancement of synaptic responses mediated by AMPA receptors in the central nervous system.
Patent CA-2450560-C (CA)
Inventor: LUPKE MANFRED A A
IPC: B29C48/09
Filed: 2003-11-24
Granted: 2006-05-16
Abstract: A pipe mold produces plastic pipe with an internal wall having a first wall portion and a second wall portion. The pipe mold, includes a cooling plug to assist in setting the pipe wall. The first wall portion of the pipe wall travels over and is in contact with the cooling plug applying heat directly to and providing a first temperature control to prevent access of cooling of the cooling plug. The second wall portion of the internal pipe wall travels over and is spaced outwardly away from the cooling plug. The pipe mold includes a second temperature control which operates in preventing the access of plug cooling as the second wall portion of the internal wall of the pipe travels over the cooling plug.
Patent CA-2452436-C (CA)
Inventor: SISKIN MICHAEL
IPC: C10G9/14
Filed: 2002-07-10
Granted: 2011-07-05
Abstract: Une forme de réalisation de cette invention concerne un procédé de réduction des amas de coke dans des écoulements de pétrole issus de processus de cokéfaction. Dans une forme de réalisation préférée, cette invention concerne un procédé qui permet de limiter l'encrassement des filtres dans le gazole du four à coke par le retardement de l'oligomérisation des diènes conjugués dans l'effluent du four à coke.
Patent CA-2455165-C (CA)
Inventor: MCGARIAN BRUCE
IPC: E21B17/06
Filed: 2002-07-30
Granted: 2009-11-10
Abstract: The present invention relates to downhole apparatus permitting separation of one part of downhole equipment from another part thereof. The invention provides downhole apparatus (2) comprising a first part (4) connected to a second part (6) by connecting means which limits axial and rotational movement between said parts. The connecting means comprises a connecting member (22) having first and second ends connected respectively to the first and second parts (4, 6). The connection of the first and second ends of the connecting member (22) is such as to limit axial and rotational movement relative to the respective first and second parts (4, 6). The connecting member (22) is provided between said first and second ends with a region of weakness in the connecting member provided by weakening means (28), and with means for minimising stress generated in the connecting means at said region of weakness when torque is transmitted in use between the first and second parts (4, 6) via the connecting member (22).
Patent CA-2456230-C (CA)
Inventor: RAICHLE PETER H
IPC: F27B7/24
Filed: 2004-01-26
Granted: 2011-09-20
Abstract: A ring sealing arrangement for an indirectly heated rotary tubular kiln between a heating tunnel and a rotating tube (20) with several overlapping segments (10), forming a sealing ring, which are pressed by application pressure elements (30) radially against the rotating tube (20). The segments (10) are essentially made of a heat-resistant, light construction sealing material. The sealing ring consists of several flat band-like sections (32), which are connected with one another, especially by springs (34), and form a tightening ring.
Patent CA-2457227-C (CA)
Inventor: FREDERIKSEN NIELS
IPC: G01L19/08
Filed: 2004-02-06
Granted: 2009-01-20
Abstract: A flow control valve for cylinders of liquefied gases having a gauge for indicating the status of the fluid, comprises a body in which there is a region provided with a shank that is adapted to be connected to a cylinder, a region for connection to user devices, a safety valve, and a movable actuation member, the actuation of which blocks the passage for the fluid from the cylinder toward the user device or clears the passage, a pressure gauge being accommodated inside the actuation member.
Patent CA-2459165-C (CA)
Title: Dosage forms having prolonged active ingredient release
Inventor: TRUOG PETER
IPC: A61P7/06
Filed: 2002-09-04
Granted: 2011-07-19
Abstract: A pharmaceutical unit dosage form comprising a therapeutically effective dose of a 4-phenylbutyric acid salt having prolonged release of the active ingredient, being suitable for alleviating and curing various diseases upon once or twice daily oral administration, a method of preparation of said pharmaceutical formulation and the use thereof for the treatment of benign prostate hyperplasy, cancer, leukemias, cystic fibrosis, AIDS, kidney and liver diseases, thalassemia and urea cycle disorders comprising the twice-daily oral administration of a therapeutically effective dosage thereof to a patient.
Patent CA-2461111-C (CA)
Inventor: WROBLEWSKI DOUG
IPC: E03F5/06
Filed: 2004-03-17
Granted: 2008-12-23
Abstract: A floor drain having a drain body that receives a rotatable frame with a grate. The orientation of the grate and frame about an. axis of the drain body may be adjusted by rotating the frame relative to the drain body and clamping the frame in the desired orientation. Adjustments to the orientation of the grate and frame can be made to align the grate and frame with floor tiles or other flooring materials and with walls surrounding the floor drain.
Patent CA-2478223-C (CA)
Title: Combinations comprising epothilone derivatives and alkylating agents
Inventor: ANDERSON JUDITH ROSE
IPC: A61P35/04
Filed: 2003-03-07
Granted: 2012-05-15
Abstract: The invention relates to a pharmaceutical combination which comprises (a) an alkylating agent and (b) an epothilone derivative of formula (I) wherein A represents O or NRN, wherein RN is hydrogen or lower alkyl, R is hydrogen or lower alkyl, and Z is O or a bond. Said combination can be useful for the treatment of a proliferative disease, especially a tumor disease.
Patent CA-2480015-C (CA)
Inventor: THOMELE ADRIAN
IPC: F41A19/45
Filed: 2003-12-19
Granted: 2007-05-15
Abstract: The invention relates to a trigger mechanism for small firearms with a striking hammer (1), a trigger (2), and a trigger rail (3), which interacts with this trigger and which can be moved by a control element from an engagement position for cocking the striking hammer (1) into a release position for releasing the cocked striking hammer (1). According to the invention, the control element is a control slide (19), which can be moved by the movement of an action (11) during repetition of the small firearm and through which the trigger rail (3) can be moved from its release position into a catch position for catching the striking hammer (1) cocked during repetition.
Patent CA-2481546-C (CA)
Inventor: CLARK JOHN DENNIS
IPC: B21B15/00
Filed: 2004-09-14
Granted: 2011-09-27
Abstract: La présente divulgation décrit des méthodes et de l'appareillage qui permettent de contrôler et de conditionner du matériau en forme de bandes. Ces méthodes et cet appareillage permettent de recevoir des signaux codés et des données de capteur pour contrôler une condition de matériau en bandes. Si une condition de matériau non désiré est détectée, un conditionneur de matériau est réglé pour obtenir la condition de matériau voulue. Chaque fois qu'une feuille est coupée, les données de planéité associées à cette feuille sont enregistrées. Chaque fois qu'un fardeau est terminé, les données de certification associées à ce fardeau sont imprimées.
Patent CA-2485590-C (CA)
Inventor: NICOLOSI GIOVANNI
IPC: E06B9/327
Filed: 2002-07-08
Granted: 2008-04-22
Abstract: System for operting a blind in a glass-enclosed chamber the ends of the said blind being respectively fitted to a fixed upper box (40) and to a movable box (60), subjected to a guide device for translation, parallel to itself, when opening and closing said blind by a pair of cords (85, 86) interacting between the fixed (40) and movable (60) boxes and a lower fixed box (50), and also to a pulling device comprising a small box containing permanent magnets fixed to the movable box (60) and a free knob, containing permanent magnets of opposing pole, so that by matching, through a pane of glass, the magnets in said knob with those fixed to the movable box (60), the blind can be opened or closed as desired.
Patent CA-2485647-C (CA)
Inventor: KIESWETTER ROBERT E
IPC: F23D11/44
Filed: 2003-05-15
Granted: 2011-07-12
Abstract: A heating unit has a cartridge that constitutes a single component, which can be readily removed and replaced with a new cartridge. The cartridge is a plurality of non-flammable layers bound together in a border. The layers include a stainless steel mesh located above a layer of ceramic wool. With the cartridge, replacement can be accomplished in approximately fifty minutes compared to a downtime of a week or more previously.
Patent CA-2489284-C (CA)
Title: Cladding apparatus, method and system
Inventor: PODIRSKY BERNHARD
IPC: E04D13/158
Filed: 2003-06-13
Granted: 2012-12-11
Abstract: There is provided cladding apparatus comprising a body portion (108) having an inner surface (110) and an outer surface (112) extending longitudinally between a leading edge (114) and a trailing edge (116) and transversely between opposed side edges (118). The leading edge (114) is provided with a formation (124) which inter-engages with complementary formation (126) provided on an adjacent body portion thereby permitting the body portions to inter-engage when laid in a longitudinal sequence. The body portion (108) is provided with a pair of longitudinally extending elongate mounting portions (128) on the inner surface (110) thereof. A longitudinal mounting batten (144) is attached to the fascia panel (106) adjacent to the exposed edge of the tiles (104), and into which the elongate mounting portions (128) may slide. A roof batten (132) is laid on the tiles and has on its lower face a plurality of steps which compensate for the overlapping nature of the tiles to provide a level upper face (140) when laid on the tiles (104), the upper face (140) forming a labyrinth with the inner surface (110) to assist in excluding weather in use.
Patent CA-2491604-C (CA)
Title: Transformer coupler for communication over various lines
Inventor: ABRAHAM CHARLES
IPC: H04B3/56
Filed: 1995-06-30
Granted: 2008-04-22
Abstract: Apparatus for electrical line communication that includes a coupler at each of two or more locations along a pair of lines, the coupler having capacitive circuits serially connected with an air-core transformer. The capacitive circuit is designed to resonate with the air-core transformer at a preselected frequency. A transmitter, receiver and modem may also be provided at each location. The apparatus incorporates a novel phase linear coupler which eliminates noise and is matched resistively to the characteristic impedance of the line at a preselected frequency. This apparatus therefore linearizes communication on the line and allows high speed data and voice communication over long distances.
Patent CA-2492329-C (CA)
Title: Method and device for high-temperature heat treatment and densification by chemical infiltration of carbon texture in a steam phase
Inventor: SION ERIC
IPC: C04B35/83
Filed: 2003-07-11
Granted: 2011-04-19
Abstract: Heat treatment is performed on preforms placed in an enclosure (11) accompanied by sweeping with an inert gas under reduced pressure, and with a gaseous effluent being exhausted continuously via a first effluent outlet (40) connected to an effluent exhaust circuit. At the end of the heat treatment, the first gaseous effluent outlet is closed so as to isolate the effluent exhaust circuit from the enclosure, sweeping of the enclosure with the inert gas is interrupted, and the heat-treated preforms are left in the enclosure and are subjected to densification by admitting a reagent gas into the enclosure via at least one reagent gas admission duct (32) opening out into the enclosure, with gaseous effluent being exhausted via a second effluent outlet (60) separate from the first, said second outlet being closed during the heat treatment step. Advantageously, metal, in particular sodium, contained in the gaseous effluent exhausted from the enclosure during the heat treatment step is neutralized.
Patent CA-2493163-C (CA)
Inventor: BOLANOS HENRY
IPC: A61B17/04
Filed: 1994-04-19
Granted: 2007-03-06
Abstract: A stent for use in surgery comprising a plurality of interrelating stent portions, each said portions having a generally planar portion integral with a generally curved portion, the stent portions being arranged such that the generally curved portion is aligned along a longitudinal axis and at least one generally planar portion is disposed on one side of the longitudinal axis and at least one generally planar portion is disposed on the other side of the longitudinal axis, planar portions are symmetrical with respect to a plane passing through the longitudinal axis, the stent is in a sterile condition, the generally curved portion is at least partially cylindrical in configuration, and at least one generally curved portion has a longitudinal aperture adapted to receive an elongate stent rod therethrough.
Patent CA-2494764-C (CA)
Inventor: JANSEN BURKHARD
IPC: A61P35/00
Filed: 2003-08-21
Granted: 2013-04-23
Abstract: Treatment of melanoma is achieved through reduction in the effective amount of clusterin in melanoma cells. Thus, in accordance with one aspect of the invention, there is provided a method for treatment of melanoma in a mammalian subject, preferably a human, comprising the step of administering to the subject a therapeutic agent effective to reduce the effective amount of clusterin in the melanoma cells. The therapeutic agent may be, for example, an antisense ODN or small inhibitory RNA (siRNA) compound targeted to clusterin. The present invention also provides a method for regulating expression of bcl-xL in a subject or cell line comprising administering to the subject or cell line an agent effective to modulate the amount of clusterin expression. In particular, in clusterin expressing cells, the expression of bcl-xL is down-regulated when the effective amount of clusterin is reduced. Such inhibition is significant because bcl-xL is known to act as an inhibitor of apoptosis.
Patent CA-2497013-C (CA)
Inventor: RUSS SAMUEL H
IPC: H04N7/173
Filed: 2003-08-18
Granted: 2012-10-23
Abstract: L'invention concerne des systèmes et des procédés permettant de fournir des objets à un terminal de communication domestique numérique éloigné (DHCT éloigné) par le biais d'un dispositif de passerelle situé dans les locaux d'un client. Un tel procédé, parmi d'autres, consiste à recevoir un message à partir d'un DHCT éloigné demandant un objet de plateforme, à recevoir l'objet de plateforme à partir d'un dispositif de serveur, et à transmettre l'objet de plateforme au DHCT éloigné.
Patent CA-2500860-C (CA)
Inventor: DINIUS CYNTHIA SUE
IPC: C09J7/20
Filed: 2003-10-17
Granted: 2009-12-01
Abstract: The present invention provides a multifunctional food wrap comprising a material web, an adhesive, and at least one secondary function. The material web is provided with a plurality of protrusions integral with the material w eb and having spaces therebetween. The adhesive is disposed within the spaces between the protuberances. The at least one secondary function may be a chemical means or a physical means and disposed within the adhesive, the material web, and/or the protuberances.
Patent CA-2503334-C (CA)
Title: Treadmill control system
Inventor: LANTZ KENNETH F
IPC: A63B22/02
Filed: 2000-09-07
Granted: 2005-11-15
Abstract: A microprocessor based exercise treadmill control system is disclosed which includes various features to enhance user operation. These features include programs operative to: permit a set of user controls to cause the treadmill to initially operate at predetermined speeds; permit the user to design custom workouts; permit the user to switch between workout programs while the treadmill is in operation; and perform an automatic cooldown program where the duration of the cooldown is a function of the duration of the workout or the user's heart rate. The features also include a stop program responsive to a detector for automatically stopping the treadmill when a user is no longer on the treadmill and a frame tag module attached to the treadmill frame having a non-volatile memory for storing treadmill configuration, and operational and maintenance data.
Patent CA-2503338-C (CA)
Inventor: UTZ ZACHARY
IPC: B65H31/38
Filed: 2003-10-17
Granted: 2012-11-27
Abstract: An automated banking machine (10) accepts deposit items such as currency, checks, gift certificates or other items of value. Deposited items after being accepted in the machine and processed are moved to the container (260). The container includes an interior area (268) which is bounded by a shaker member (282) on which deposit items are supported. The machine is operative to control operation of an actuator (290) which moves the shaker member to impart shaking motion to deposited items (278) to facilitate the compact storage thereof within the container. The container is enabled to be removed from the machine to facilitate removal of the deposited items. Movement of the container out of and away from the machine is facilitated by rollable supports (296) and a retractable handle (298).
Patent CA-2504101-C (CA)
Title: Connection systems and methods for utility meters
Inventor: JOHNSON RICHARD R JR
IPC: H01R/
Filed: 2004-06-07
Granted: 2010-05-11
Abstract: A connection system for allowing access to a primary power signal flowing through a utility meter. The connection system comprises a collar assembly (14), an adapter assembly (12), and adapter electronics (38). The collar assembly comprises a collar housing (40) adapted to engage the wall box and the meter assembly, a plurality of main terminals (50), a plurality of secondary terminals (52). The adapter assembly comprises an adapter housing (30) and a plurality of adapter contacts (34). The adapter housing is sized and dimensioned to be arranged in an engaged position relative to the collar housing. The adapter contacts engage the secondary contacts when the adapter housing is in the engaged position. The adapter electronics are contained within the adapter housing and are electrically connected to the adapter contacts.
Patent CA-2508430-C (CA)
Title: Joystick arrangement
Inventor: OLSEN JESPER BLOCH
IPC: H02J17/00
Filed: 2005-05-26
Granted: 2008-07-29
Abstract: The invention concerns a joystick arrangement (1) with a basic unit (3) and a movable handle unit (2), which com-prises at least one electrical function element (15) with an energy supply connection and an endpoint of a wireless signal transmission path. It is endeavoured to simplify the mounting. For this purpose, the energy supply connection is con-nected with a power receiver (16) located in the handle unit (2), which power receiver (16) can be supplied with energy via a wireless power transmission path (20).
Patent CA-2511868-C (CA)
Title: Electrical deionization apparatus
Inventor: TAKAHASHI YOHEI
IPC: C02F1/469
Filed: 2003-12-26
Granted: 2011-03-15
Abstract: It is an object of the present invention to provide an electrical deionization apparatus having a novel constitution with excellent deionization efficiency. As means for solving this problem, according to one embodiment of the present invention, there is provided an electrical deionization apparatus having deionization compartments, concentration compartments and electrode compartments partitioned from one another by a plurality of ion exchange membranes between a cathode and an anode, wherein, in the deionization compartments and/or the concentration compartments and/or the electrode compartments, at least one of anion exchange fibrous material layers and cation exchange fibrous material layers are disposed on one another intersecting a water-passing direction.
Patent CA-2512338-C (CA)
Title: Port adapter network-analyzer
Inventor: AGRAWAL PAWAN
IPC: H04L12/24
Filed: 2003-12-18
Granted: 2010-05-25
Abstract: Methods and devices are provided for encapsulating FC frames from a network device as Ethernet frames. Preferably, the FC frames represent traffic for a plurality of ports of the network device. The encapsulated Ethernet frames may be input to a conventional network interface card of a personal computer ("PC") or laptop. Therefore, encapsulating the FC frames allows an engineer to use software installed on a conventional PC to troubleshoot problems with a network using FC protocol. According to some aspects of the invention, FC  frames may be truncated to various degrees, to allow smaller data frames to be output at an appropriate rate to the analyzing personal computer, laptop, etc.
Patent CA-2512443-C (CA)
Inventor: GAMBIER PHILIPPE
IPC: E21B47/06
Filed: 2005-07-19
Granted: 2008-09-30
Abstract: One aspect of the present invention is a system and method to measure a pressure or other measurement at a source (e.g. a hydraulic power supply) and in or near a downhole tool and compare the measurements to verify that, for example, the supply is reaching the tool. Another aspect of the present invention is a system and method in which a gauge is positioned within a packer. Yet another aspect of the invention relates to a gauge that communicates with the setting chamber of a packer as well as related methods. Other aspects and features of the system and method are also described. It is emphasized that this abstract is provided to comply with the rules requiring an abstract, which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
Patent CA-2513398-C (CA)
Inventor: YOON HEEJEONG
IPC: C12Q1/68
Filed: 2004-01-28
Granted: 2013-09-10
Abstract: New antisense oligonucleotide compounds, RX-0047 and RX-0149, inhibit expression of HIF-1 and also induce cytotoxicity in several cancer cell lines.
Patent CA-2513848-C (CA)
Inventor: TERADA SHIGEO
IPC: B60L50/10
Filed: 2005-07-26
Granted: 2008-03-18
Abstract: An outboard motor is equipped with a centrifugal clutch located between t he crankshaft of an engine and a rotor of the electric motor for, when the engi ne operates, transmitting its output to through the rotor to the propeller, and with the motor output transmission mechanism for, when the engine does not operate, transmitting the output of the motor to the crankshaft. The engine can therefore be started by the motor used to drive the propeller. As a result, there is no need to install a separate electric motor for engine starting, so that starting of t he engine by electric power can be made possible with minimum increase in the size and co st of the outboard motor.