baber/WOPTO huggingface dataset:
Patent JP-2716387-B2 (JP)
IPC: A61K8/00
Filed: 1994-12-27
Granted: 1998-02-18
Abstract: New water in oil (w/o) emulsions contain retinol, an oil phase, an aq. phase and an emulsifier. The oil phase contains an organic solvent for retinol. The aq. phase has a basic pH. Also claimed is a device for packaging a prod., equipped with a distribution device such that the prod. does not come into contact with the environment. The walls of the device are impermeable to gases, UV and visible light, and the contact surface of the walls with the prod. is non-metallic. The appts. also contains an O2-capturing device.
Patent JP-H0654148-B2 (JP)
IPC: F16L17/02
Filed: 1987-12-25
Abstract: An annular gasket of a soft elastic material is fixed in a groove in a socket (14) which is to receive a pipe end (9). Attached to the annular leading edge (A) of the main gasket body relative to the pipe end (9) is a closed, annular hollow jacket (22) which during insertion of the pipe end (9) is entrained so as to form a double layer over the adjacent surface (4) of the main gasket body, the surface (4) being presented to the pipe end (9) by a sliding part (2) of the main gasket body. When fully inserted, the pipe end (9) compresses the main gasket body between the double layer formed by the jacket (22) and the socket (14).
Patent JP-H0819087-B2 (JP)
IPC: C07D317/26
Filed: 1993-12-02
Abstract: The present invention relates to a process for the preparation of vitamin A which consists in placing cyclogeranylsulphone in contact with a C10 aldehyde acetal, in halogenating the derivative obtained and in then removing the halogen group and the sulphone, in removing the acetyl group and in rectifying the retinal obtained.
Patent JP-2505841-B2 (JP)
IPC: C23C2/28
Filed: 1987-12-29
Granted: 1996-06-12
Abstract: The invention relates to a method for producing a non-aging hot-dip galvanized steel strip in a hot-dip galvanizing line with a continuous over-aging furnace at the end thereof. The steel strip is rapidly cooled from a temperature of 600 to 700 DEG C to a temperature of about 460 DEG C by quenching the steel strip in a zinc bath. Thereafter a steel strip is further cooled to a temperature preferably below 300 DEG C and the steel strip is then brought into the continuous over-aging furnace. The temperature of said furnace is about 350 DEG C and the over-aging treatment takes preferably from 2 to 3 minutes. A furnace has guide rolls arranged outside the furnace walls and the steel strip is momentarily cooled before making contact with a guide roll. After leaving the over-aging furnace, the steel strip is subjected to conventional air and water cooling as well as temper-rolling.
Patent JP-H07107053-B2 (JP)
IPC: C07D215/12
Filed: 1988-11-01
Abstract: This invention relates to quinoline derivatives (I), their use in the treatment of hypersensitive ailments and a pharmaceutical composition containing the same. They are especially valuable as lipoxygenase inhibitors and/or leukotriene antagonists, typically antagonists of leukotriene D4, possessing anti-inflammatory and anti-allergic properties. <CHEM>  a is 0-2;  b is 0-1;  c is 0-4;  d is 0-5;  e is 0-4;  f is 0-5;  n is 0-2; R is independently hydrogen, alkyl, hydroxy, alkoxy, carboxy, carbalkoxy, halo, nitro, haloalkyl, cyano or acyl; R min  is independently hydrogen, alkyl, hydroxy, alkoxy, halo or haloalkyl;  R1 is independently hydrogen, alkyl or aralkyl;  R2 is -(CH2)x - X, where x is 0-3; X is hydrogen, alkyl, alkenyl, cycloalkyl, aryl aralkyl, hydroxy, alkoxy, aralkoxy, amino, mono-and di-alkylamino, aralkylamino, acylamino, carbamyl, carboxy, carbalkoxy, tetrazolyl, or acylsulfonamido; vicinal R2 groups together may be (CH2)y - where y is 1-4, thus forming a 3-6 membered ring; geminal R1 and R2 groups may together form a spiro substituent, -(CH2)z -, where z is 2 to 5; geminal R1 or R1 and R2 groups may together form an alkylidenyl substituent, =CHR1;   Z is -COOR1, CN, - @NHSO2R3, -@N(R1)2, -OR1, tetrazolyl or substituted tetrazolyl where the substituent may be alkyl, carboxyalkyl or carbalkoxyalkyl; and R3 is hydrogen, alkyl, haloalkyl, phenyl or benzyl; or a pharmaceutically acceptable salt thereof.
Patent JP-2566374-B2 (JP)
IPC: C07C233/14
Filed: 1992-07-03
Granted: 1996-12-25
Abstract: PCT No. PCT/EP92/01497 Sec. 371 Date Jan. 10, 1994 Sec. 102(e) Date Jan. 10, 1994 PCT Filed Jul. 3, 1992 PCT Pub. No. WO93/01162 PCT Pub. Date Jan. 21, 1993.The invention provides the substantially geometrically pure cis-stereoisomeric form of a compound of formula (I) and the substantially geometrically and optically pure cis-stereoisomeric form of a compound of formula (II):    <IMAGE>  (I)   <IMAGE>  (II)  wherein R1 is H or C1-C4 alkyl, together with processes for their preparation. The compounds are intermediates for the preparation of the antidepressant agent known as sertraline.
Patent JP-4549440-B2 (JP)
IPC: G01N15/14
Filed: 1997-05-29
Granted: 2010-09-22
Abstract: Hematology reference control cells and method of manufacture. The invention relates to the methods of preparing stable white blood cell ("WBC") and nucleated red blood cell ("NRBC") fractions and the hematology control reagents containing such stablized cells for primary use on a multi-angle light scatter based hematology instrument.
Patent JP-3616640-B2 (JP)
IPC: E04G1/32
Filed: 1993-07-22
Granted: 2005-02-02
Abstract: A support leg comprising an upstanding member (12) and securing means (18) for securing an elongate member (44) to the upstanding member (12). When the elongate member is secured to the upstanding member, a planar member (42A to 42E) can be supported on the elongate member to define at least a part of a platform (40). The securing means is movable from a securing position to secure the elongate member (44) to the upstanding member (12) and a non-securing position where member can be removed from the upstanding member. The support leg is suitable for use in forming a platform (40).
Patent JP-3427937-B2 (JP)
IPC: A61P25/24
Filed: 1993-07-23
Granted: 2003-07-22
Abstract: The present invention relates to novel 2-substitited indane-2-mercaptoacetylamide tricyclic derivatives which are useful as inhibitors of Enkephalise.
Patent JP-2852404-B2 (JP)
IPC: H01F7/02
Filed: 1991-02-20
Granted: 1999-02-03
Abstract: A permanent magnetic structure comprising a cylindrical body (15) and a termination structure (14, 12, 10). The cylindrical body (15) is composed of magnetic material causing a magnetic field and flux of magnetic induction. The cylindrical body (15) is oriented such that the interface between the cylindrical body 15 and the termination (14, 12, 10) is parallel to the magnetic induction and the cylindrical body (15).
Patent JP-3097756-B2 (JP)
IPC: C09G1/04
Filed: 1995-08-23
Granted: 2000-10-10
Abstract: Before washing with water and drying a car in the usual manner, an emulsion containing 0.5 to 10 % by weight wax and/or 2.5 to 15 % by weight silicone, 0.2 to 10 % by weight emulsifier, 0 to 2 % by weight thickener in an emulsifying or dispersing liquid, and if required additives such as fragrances, dyes, UV absorbing agents, anti-static agents and abrasive agents, is applied and spread on the surface of the car.
Patent JP-3066385-B2 (JP)
IPC: C07K19/00
Filed: 1991-06-01
Granted: 2000-07-17
Abstract: This invention relates to a 16 kDa surface protein capable of inducing an immune response protective against human malarial infection caused by Plasmodium falciparum, and to the cloning and expression of a gene encoding the said protein. The invention further relates to novel vaccines comprising the said protein and to their use in the vaccination of humans at risk from malaria.
Patent JP-3297433-B2 (JP)
IPC: C07K16/00
Filed: 1990-06-13
Granted: 2002-07-02
Abstract: The present invention provides a fail-safe combination of chemical and physical means for rendering a blood product which comprises a labile blood protein free of viruses without incurring protein denaturation. The blood product is contacted with an effective amount of a selected chemical disinfectant, preferably, sodium thiocyanate in combination with a physical process, preferably, ultrafiltration. The blood product may be plasma, serum, plasma concentrate, cryoprecipitate, cryosupernatant, plasma fractionation precipitate or plasma fractionation supernatant containing viruses such as hepatitis or human immunodeficiency virus.
Patent JP-2919964-B2 (JP)
IPC: A61K9/00
Filed: 1990-08-31
Granted: 1999-07-19
Abstract: A dosage form is disclosed comprising the antidiabetic drug glipizide for administering to a patient in need of glipizide therapy.
Patent JP-4005634-B2 (JP)
IPC: A61K47/48
Filed: 1996-10-11
Granted: 2007-11-07
Abstract: An isolated and purified non-denatured transferrin receptor protein of a Moraxella strain, particularly M. catarrhalis, has an apparent molecular mass of about 80 to about 90 kDa, as determined by SDS-PAGE. The transferrin receptor protein or a fragment analog thereof is useful in diagnostic applications and immunogenic compositions, particularly for in vivo administration to a host to confer protection against disease caused by a strain of Moraxella. The transferrin receptor protein is isolated from strains of Moraxella catarrhalis by a procedure including extraction of agent soluble proteins of a cell mass produced by cultivating the strain under iron-starved conditions. The transferrin receptor protein is selectively solubilized from the extracted cell mass and purified.
Patent JP-3623960-B2 (JP)
IPC: C25B3/23
Filed: 1993-02-19
Granted: 2005-02-23
Abstract: A process is disclosed in which optically active glycols are produced through an electrolytic asymmetric dihydroxylation (ADH) reaction involving olefins as substrates. The ADH reaction is mediated by a catalytically active amount of osmium tetroxide or osmium-containing precursor in a protic medium in the presence of chiral ligand. Any lower valent osmium species produced in the course of the ADH reaction is regenerated electrolytically either directly in the absence of a secondary oxidant or indirectly in the presence of a secondary oxidant that itself undergoes electrolytic regeneration.
Patent JP-3710141-B2 (JP)
IPC: G01N33/74
Filed: 1994-05-13
Granted: 2005-10-26
Abstract: A method of examining hormone-dependent tumors which comprises culturing tumor tissues in each of (a) a medium, (b) a medium containing a hormone synthetase substrate, and (c) a medium containing both a hormone synthetase substrate and a hormone synthetase inhibitor, measuring the growth rate of tumor cells in each medium, determining (i) the ratio of the growth rate of tumor cells in the presence of a hormone synthetase substrate to that in a medium alone and (ii) the ratio of the growth rate of tumor cells in the presence of both a hormone synthetase substrate and a hormone synthetase inhibitor to that in a medium alone. This method enables judging whether there are any hormone synthetase and hormone-dependent growth of hormone-dependent tumors readily at the same time. Further it can be employed for developing a new method of classifying tumors and selecting a guide line for tumor therapy.
Patent JP-4528370-B2 (JP)
IPC: C01F11/18
Filed: 1996-10-22
Granted: 2010-08-18
Abstract: The invention concerns a micronized alkaline earth metal carbonate prepared with or without the use of an agent preventing crystal growth, and a process for its preparation and use. The prepared micronized calcium carbonate, barium carbonate with a BET surface area ranging from 3 to 30 m2/g or strontium carbonate with a BET surface area ranging from 3 to 50 m2/g is suitable in particular for preparing capacitors, thermistors and other oxide ceramic electrical components containing calcium oxide, barium oxide or strontium oxide, and high-temperature superconductors. Ammonium salts or alkylammonium salts of carboxylic acids having a total of between 3 and 12 carbon atoms and at least two COOH groups or at least two OH groups, e.g. salts of maleic acid or nitric acid, are used as agents preventing crystal growth.
Patent JP-3088469-B2 (JP)
IPC: F04B45/053
Filed: 1996-10-25
Granted: 2000-09-18
Abstract: A pump having a center section including an actuator housing and an air valve is arranged with air chambers to either side of the actuator housing. Diaphragms are associated with the air chambers to create enclosed cavities for alternately pressurizing and venting the diaphragms. The actuator uses a pilot shifting shaft which is shuttled by movement of the diaphragms. An air valve is controlled by the shuttle shifting shaft to control flow to and from the air chambers. The passageways from the air chambers to exhaust find the passage to the outlet being at least as restrictive to air flow as the remainder of the passageways so as to prevent major pressure decreases within the actuator body. A diffuser includes a thin space between two surfaces into which the exhaust is directed. One of the surfaces is associated with a porous block of material. Exhausting air is distributed within the space and then passed through the porous block of material. The cylindrical orifice through which flow radially passes is roughly the same cross section as the restricted exhaust passageway. The air valve includes a cylinder closed at one end with an end cap positioned at the other end. The end cap is arranged with a plug that fits within the cylinder so as to seal without close tolerance on axial positioning. Bolts retaining the air valve and the actuator housing also retain the end cap as well.
Patent JP-3524924-B2 (JP)
IPC: F16B27/00
Filed: 1994-02-16
Granted: 2004-05-10
Abstract: A driver for fasteners, and particularly, a power screwdriver is described which is adapted to drive screws having different diameters. The power screwdriver has a removable guide tube and a complementary drive shaft. The guide tube is sized to the diameter of one size of screw. The complementary removable drive shaft is sized to be guided in the guide shaft, reciprocally movable therein to engage and guide a screw located in the guide tube. By removal of one pair of guide tube and complementary drive shaft and replacement with another pair of guide tube and complementary drive shaft adapted for use with screws having a different head diameter, the driver is adapted for driving screws of different head diameters.
Patent JP-3391795-B2 (JP)
IPC: F25B17/08
Filed: 1994-04-20
Granted: 2003-03-31
Abstract: In a sorption reaction system comprising one or more first reactors (10) in which a refrigerant is alternately adsorbed and desorbed, and one or more second reactors (20) in which a refrigerant is alternately desorbed and adsorbed, respectively, and having a cooling loop (16, 60, 68, 67, 56, 12, 21) for directing heat transfer fluid to and from said reactors (10, 20), a method of cooling an adsorbing reactor comprises directing liquid phase heat transfer fluid having a phase change from liquid to gas at a temperature at or below the temperature of adsorption to an adsorbing reactor in heat exchange exposure to the adsorbent utilizing vaporized heat transfer fluid for driving the liquid heat transfer fluid in the cooling loop. The refrigerant may be used as the heat transfer fluid. The invention includes apparatus for carrying out the method.
Patent JP-2863638-B2 (JP)
IPC: C07H15/26
Filed: 1997-01-23
Granted: 1999-03-03
Abstract: Formation of an intramolecular cross-link in enzyme donor polypeptide fragments of  beta -galactosidase, thereby forming a cyclic enzyme donor which is hindered from complementation with an enzyme acceptor fragment to form active of  beta -galactosidase. The cyclic enzyme donor can be linearized by cleaving to restore complementation ability. Assays in which such cyclic enzyme donors are linearized by specific analytes are disclosed, as well as novel homobifunctional bis-maleimido cross-linking agents of the formula wherein R is hydroxy or acetate.
Patent ES-2238020-B2 (ES)
Title: Procedimiento de preparaciones de 1,2-nitroalcoholes opticamente activos.
Inventor: PALOMO NICOLAU CLAUDIO
IPC: C07C205/14
Filed: 2005-04-15
Granted: 2006-04-01
Abstract: Procedimiento de preparación de 1,2-nitroalcoholes ópticamente activos. La invención describe un procedimiento para la preparación de 1,2-nitroalcoholes quirales no racémicos altamente enriquecidos en sus formas enantio y diastereoméricas de fórmula I, de interés en el campo de la biomedicina, así como intermedios en la preparación de 1,2-aminoalcoholes con propiedades terapéuticas. El nuevo procedimiento consiste en que, sobre una mezcla que comprenda la suspensión de una sal de zinc en un nitroalcano de fórmula III, se adiciona una amina terciaria y un 1,2-aminoalcohol ópticamente activo de fórmula IV y se mantiene en agitación un tiempo a 20° C. La mezcla se hace reaccionar con un compuesto carbonílico de fórmula II a temperaturas de -40 a 25° C y tiempos de 15 a 18 h, obteniéndose 1,2-nitroalcoholes de fórmula I y recuperándose el aminoalcohol IV, para ser reciclado en el procedimiento. Los grupos R1, R2, R3, R4, R5, R6, R7 y R8 tienen la significación dada en la memoria.
Patent ES-2277791-B2 (ES)
Title: Elemento de caucho armado y su procedimiento de fabricacion.
Inventor: BENCOMO ENSESA JOAQUIN
IPC: E01F15/04
Filed: 2006-10-31
Granted: 2008-05-01
Abstract: Elemento de caucho armado y su procedimiento de fabricación. Comprende esencialmente una estructura metálica o de material mecánicamente resistente que se encuentra perforada, y recubierta completamente por una mezcla formada por un porcentaje comprendido entre el 85 y el 95% de granza de caucho, reciclada o no, un porcentaje comprendido entre el 5 y el 15% de material adhesivo, polimérico o similar para conferir al elemento un estado totalmente compacto, y opcionalmente uno o varios colorantes o pigmentos para darle la coloración externa al elemento; cuya finalidad principal es ofrecer una gran resistencia mecánica, una buena absorción al ruido, un buen aislamiento térmico, una gran impermeabilidad, y una gran absorción al impacto; y cuyo proceso de fabricación es por moldeo.
Patent ES-2632888-B2 (ES)
Title: Dispositivo de compactación de polvos para obtener piezas sinterizadas con porosidad gradiante radial, procedimiento de obtención y uso
Inventor: RODRIGUEZ ORTIZ JOSÉ ANTONIO
IPC: B22F3/02
Filed: 2016-03-14
Granted: 2018-01-19
Abstract: La presente invención tiene por objeto un dispositivo que permite realizar dos compactaciones o más concéntricas, en distintas etapas de llenado y compactación, pudiendo emplear masas y presiones diferentes que, una vez sinterizadas, dan como resultado zonas de diferente porosidad en una única pieza y con una transición en gradiente según el diseño. Es de aplicación en soluciones para implantes óseos, piezas autolubricadas, disipadores de calor de alta eficiencia y simulación de combustibles nucleares.
Patent AU-2001253506-B2 (AU)
Title: A method and an apparatus for a quick retransmission of signals in a communication system
Inventor: ATTAR RASHID A
IPC: H04W92/10
Filed: 2001-04-13
Granted: 2005-11-24
Abstract: A method for wireless communication, comprising: receiving data in multiple forward link timeslots; determining a quality metric of the received data; requesting retransmission of the data via a first request scheme if the quality metric indicates the data has not been received correctly; and if retransmission is requested and the data is not received correctly, requesting retransmission of the data via a second request scheme.
Patent AU-2001277488-B2 (AU)
Title: Prochelators of radiometal labeled molecules
Inventor: MAECKE HELMUT R
IPC: A61K51/00
Filed: 2001-05-11
Granted: 2006-05-18
Abstract: Chelating compounds for labeling bioactive molecules with a radiometal, having general formula (I) in which: both Y groups may be positioned either trans as shown or cis; A is an effector molecule, such as a peptide, in particular octreotide, CCK, substance P, gastrine, a protein, in particular an antibody or enzyme, sugars or radiosensitizing agents, like doxorubicin; R is a hydrogen, a C<SUB>1</SUB>-C<SUB>3 </SUB>alkyl or a alcohol; X is a spacer, in particular (CH<SUB>2</SUB>)<SUB>n</SUB>-X', in which n is 1-10 and X' is COOH, NH<SUB>2</SUB>, SH, OH or O-halogen, in which halogen is in particular Br, I or Cl, or a molecule of the formula (a) or of the formula (b), Y is COO-, CH<SUB>2</SUB>CONH<SUB>2</SUB>, CH<SUB>2</SUB>CH<SUB>2</SUB>OH, optionally complexed with a radiometal.
Patent AU-2002222207-B2 (AU)
Title: Serine protease inhibitors
Inventor: LIVELY SARAH ELIZABETH
IPC: C07D307/54
Filed: 2001-12-12
Granted: 2006-09-21
Abstract: Compounds of formula (I) where R<SUB>5</SUB>, R<SUB>6a</SUB>, each X, L, Cy and Lp are as defined in the specification, are tryptase inhibitors useful as antiinflammatory agents.
Patent AU-2002234209-B2 (AU)
Title: Expansion-assisting delivery system for self-expanding stent
Inventor: SHELSO SUSAN I
IPC: A61F2/82
Filed: 2002-01-03
Granted: 2005-09-22
Abstract: The present invention relates to a delivery system for a self-expanding stent.  The delivery system comprises an inner member having a distal end, the inner member being configured to retain a self-expanding stent proximate the distal end, the inner member including a first marker band (64) such that, when the self-expanding stent is retained proximate the distal end, the first marker band (64) is disposed between a distalmost leading end of the self-expanding stent and a trailing end of the self-expanding stent, wherein the marker band indicates a reconstrain limit of a partially-expanded, self-expanding stent; 
an outer member positioned about the inner member, the outer member being slidable relative to the inner member in an axial direction; 
a holding sleeve positioned such that, when the self-expanding stent is retained proximate the distal end, the holding sleeve is within an interior of the stent and cooperates with the outer member so as to retain the positioning of the stent; and 
an inflatable device positioned about the inner member, wherein the inflatable device is disposed between the holding sleeve and the distal end of the inner member.
Patent AU-2002236221-B2 (AU)
Title: Method for producing hollow yarn film
Inventor: HAMANAKA KATSUHIKO
IPC: B01D71/34
Filed: 2002-03-05
Granted: 2004-09-23
Abstract: In a method for producing hollow fiber membranes which comprises melt kneading a mixture comprising polyvinylidene fluoride and an organic liquid or a mixture comprising polyvinylidene fluoride, an organic liquid and an inorganic fine powder, extruding the kneaded mixture to form hollow fibers, and extracting the organic liquid or the organic liquid and the inorganic fine powder from the hollow fibers, which includes the steps of drawing the hollow fibers before or after termination of the extraction and then shrinking the fibers. According to this method, it is possible to stably produce hollow fiber membranes having dense pores and having a high water permeation performance, excellent endurance and stain resistance, and which are suitable for filtration uses such as removal of turbidity of water. <IMAGE>
Patent AU-2002301473-B2 (AU)
Title: Vertebral endplate chisel
Inventor: ROGERS CHRISTOPHER
IPC: A61B17/17
Filed: 2002-10-15
Granted: 2007-08-02
Abstract: A vertebral endplate chisel comprises:   a. a base having upper and lower portions, and proximal and distal portions, b. an upper shaving portion extending distally from the upper base portion, and c. a lower shaving portion extending distally from the lower base portion, in which the upper and lower shaving portions are disposed substantially parallel to each other and each having a width, and d. a guide integrally connected to and extending distally from the base and having a width, the guide located between the shaving portions and having a width, in which the width of the guide is no more than 95% of the width of the upper shaving portion. <IMAGE>