baber/WOPTO huggingface dataset:
Patent NZ-572862-A (NZ)
Title: DPP IV inhibitor formulations which comprise mannitol, pregelatinised starch, copovidone, corn starch and magnesium stearate
Inventor: KOHLRAUSCH ANJA
IPC: A61K38/095
Filed: 2007-04-30
Abstract: Disclosed are pharmaceutical compositions which comprise as an active ingredient a DPP IV inhibitor compound selected from 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine, 1-[([1,5]naphthyridin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, 1-[(quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, 2-((R)-3-amino-piperidin-1-yl)-3-(2-butyn-1-yl)-5-(4-methyl-quinazolin-2-ylmethyl)-3,5-dihydro-imidazo[4,5-d]pyridazin-4-one, 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(2-amino-2-methyl-propyl)-methylamino]-xanthine, 1-[(3-cyano-quinolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-aminopiperidin-1-yl)-xanthine, 1-(2-cyano-benzyl)-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(S)-(2-aminopropyl)-methylamino]-xanthine, 1-[(3-cyano-pyridin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-aminopiperidin-1-yl)-xanthine, 1-[(4-methyl-pyrimidin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, 1-[(4,6-dimethyl-pyrimidin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, or 1-[(quinoxalin-6-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((R)-3-amino-piperidin-1-yl)-xanthine, or a salt thereof, a first diluent which is mannitol, a second diluent which is pregelatinised starch, a binder which is copovidone, a disintegrant which is corn starch and a lubricant which is magnesium stearate. Further disclosed is a pharmaceutical oral dosage form which comprises 1-[(4-methy]-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine in an amount of 0.5 mg, 1 mg, 2.5 mg, 5 mg or 10 mg, a first diluent which is mannitol, a second diluent which is pregelatinized starch, a binder which is copovidone, a disintegrant which is corn starch, and a lubricant which is magnesium stearate.
Patent NZ-578689-A (NZ)
Title: Managing data using only data channel stateless server agents and no stateful middleware
Inventor: HARVEY PETER
IPC: G06F15/173
Filed: 2008-02-05
Abstract: A data management system and a method of data management for managing the storage of data on primary and secondary storage is disclosed. The data management system for managing the storage of data on primary and secondary storage from a primary information source having original file content to be stored includes a data file stub stored on primary storage and a data file stored on secondary storage. The data file stub comprises original file meta data and additional stub meta data relevant to the data file. The data file comprises the original file content and additional file meta data relevant to the data file stub where the additional stub meta data includes location and information relevant to locate and recover the data file. The additional file meta data includes information relevant to the location and content of the stub where the additional stub meta data and additional file meta data is formed and arranged such that data to be stored may be accessed without stateful middleware.
Patent NZ-578998-A (NZ)
Title: Railway bogie with steering responsive to yaw
Inventor: SIMSOM SCOTT
IPC: B61F5/44
Filed: 2008-02-21
Abstract: A railway bogie (10) with a mounted vehicle body including a frame (11), a plurality of wheelsets (12, 13), and steering linkages (21, 25, 26) linking the wheelsets so that the wheelsets can cooperate to be in steering alignment. The bogie has a wheelset body linkage (28) pivotally connecting the steering linkages with the bogie body so to position the body relative to the wheelsets and two alignment rams (30) to position the body relative to the frame. The bogie also has sensors for monitoring the yaw angle and yaw velocity. The sensor input is then processed to estimate track curvature and determine the train speed and yaw velocity of the vehicle body. The processor then actuates the alignment rams to adjust the position of the body relative to the frame in response to the track curvature and current frame positions to minimize wheel contact creepage and maximize bogie stability.
Patent NZ-579569-A (NZ)
Title: Compositions and methods for reducing h2s levels in fermented beverages
Inventor: BISSON LINDA F
IPC: C12N1/15
Filed: 2008-03-13
Abstract: Disclosed is a method for reducing H2S levels in a fermentation medium, the method comprising contacting the fermentation medium with a yeast cell comprising a polynucleotide encoding a MET 10 polypeptide that does not catalyze the conversion of sulfite into sulfide, wherein the amino acid at position 662 of the MET10 polypeptide is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, Gin, Arg, Val, Trp or Tyr (SEQ ID NO:5). Also disclosed is an improved yeast cell that does not produce hydrogen sulfide comprising an exogenous polynucleotide encoding a MET 10 polypeptide that does not catalyse the conversion of sulfite to sulfide, wherein the amino acid at position 662 of the MET 10 polypeptide is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, Gin, Arg, Val, Tip or Tyr (SEQ ID NO:5), wherein a parent cell of the improved yeast cell produces hydrogen sulfide.
Patent NZ-580537-A (NZ)
Title: Baking oven with active heating region under tray made by elements with active and inactive portions
Inventor: WILLETT PAUL EATON
IPC: A21B1/00
Filed: 2009-10-20
Abstract: Disclosed is a baking oven which comprises of: at least one oven chamber having a floor; at least one heating means for generating heat; and at least one support means including a rotatable turntable for supporting one or more baking trays (30) in a baking tray position within the heating chamber. The oven chamber has an active region (40) under the baking tray position and an inactive region positioned outwardly of the active region, the heating means being positioned to provide substantially more heat to the active region than to the inactive region for more directly heating an underside of the baking tray position. The heating means include a plurality of heating elements (20), which extend from a wall (26) of the oven into the active region. Each element has an inactive portion (21) and an active portion (22), where the inactive portion extends from the wall to the active region. The active portion extends within the active region for more directly heating an underside of the baking trays.
Patent NZ-584419-A (NZ)
Title: Supplementary bee food comprising a sugar and methylglyoxal, methylglyoxal-1,1-dimethylacetal, dihydroxyacetone and / or 2,5-dihydroxydioxane-2,5-dimethanol
Inventor: HEUER DARIA
IPC: A01K53/00
Filed: 2010-04-06
Abstract: Disclosed are compositions and uses thereof as a supplementary bee food for increasing the MGO and/or UMF number in honey; said compositions comprise: a) from 0.0001% to 30% by weight of methylglyoxal-1,1-dimethylacetal, methylglyoxal, dihydroxyacetone or 2,5-dihydroxydioxane-2,5-dimethanol; and b) a sugar such as arabinose, 2-desoxy-D-glucose, 2-desoxy-D-ribose, fructose, fucose, galactose, mannose, sorbose, adonit, dulcet, erythit, inosit, mannit and/or sorbit, xylit, galacturonic acid, gluconic acid-lactone, glucuronic acid lactone, cellubiose, lactose, lactulose, maltose, melibiose, raffinose, saccharose, trehalose, amylose, inulin or natural or synthetic mixture of these sugars or other types of honey. Further disclosed is a method of feeding Manuka honey collecting bees which comprises using a composition as defined above close to a beehive of these bees.
Patent NZ-586445-A (NZ)
Title: Phosphonic acid derivates and their use as p2y12 receptor antagonists
Inventor: CAROFF EVA
IPC: A61K31/662
Filed: 2008-11-28
Abstract: Disclosed is a compound of formula I e.g. 4-((R)-2-{ [6-((S)-3-methoxy-pyrrolidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino} -3-phosphono-propionyl)-piperazine-1-carboxylic acid ethyl ester wherein the variables are defined in the specification for the treatment of occlusive vascular disorders.
Patent NZ-593012-A (NZ)
Title: Heterocyclic aspartyl protease inhibitors and their combination with cholinesterase inhibitors or muscarinic antagonists
Inventor: ZHU ZHAONING
IPC: C07D401/14
Filed: 2004-12-13
Abstract: Disclosed are heterocyclic compounds represented by structural formula (I), a stereoisomer, tautomer, a pharmaceutically acceptable salt and solvate thereof. These heterocyclic compounds are suitable for inhibiting aspartyl protease, and are particularly used for the treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula (I) in combination with a cholinesterase inhibitor or a muscarinic antagonist.
Patent NZ-594516-A (NZ)
Title: Apolipoprotein a-i mimics
Inventor: DASSEUX JEAN-LOUIS
IPC: A61K38/16
Filed: 2010-02-12
Abstract: Provided is the peptide Lys-Leu-Lys-Gln-Lys-Leu-Ala-Glu-Leu-Leu-Glu-Asn-Leu -Leu-Glu-Arg-PheLeu-Asp-Leu-Val-Inp, which can be complexed with a lipid. The composition can be used to treat macrovascular, microvascular and cardiovascular disorders and dyslipidemia.
Patent NZ-597220-A (NZ)
Title: Fluid treatment apparatus
Inventor: CUMMINS IAN GEOFFREY
IPC: C02F1/32
Filed: 2010-06-02
Abstract: 597220 Disclosed is a fluid purification or treatment apparatus (10) for treating or purifying contaminated liquids such as water. The apparatus includes at least one upright elongated primary treatment chamber (11) having an inlet (14) for fluid to be treated at an upper end of the chamber (11) such that fluid flows downwardly through the chamber (11). Means (20 or 24) are provided for introducing a sterilizing agent such as ozone or ozone enriched air into a lower end of the chamber (11) for bubbling upwardly through liquid flowing downwardly through the chamber (11). Means (16) at the upper end of the chamber (11) remove waste and an ultraviolet lamp (29) is provided for UV treatment of the liquid, the ultraviolet lamp (29) being located in a separate chamber (12) connected to the primary treatment chamber (11) or within the primary treatment chamber (11). A plurality of chambers (11) and (12) may be provided for multiple treatment of the liquid.
Patent NZ-598637-A (NZ)
Title: Systems, methods, and apparatus for reducing network congestion in a smart utility meter system
Inventor: REE BRADLEY RICHARD
IPC: G01R11/00
Filed: 2012-03-07
Abstract: Disclosed is a utility meter (105) having first and second communications interfaces and at least one processor. The first communications interface is for communicating with a first network (110b). The second communications interface is for communicating with a second network (115b) different from the first network (110b). The at least one processor in communication with the first and second communications interfaces, the at least one processor is configured to receive or generate information having a destination and select either the first communications interface or the second communications interface. The processor then delivers the information to the destination via the selected communications interface.
Patent NZ-600909-A (NZ)
Title: Oligonucleotides and methods for detecting lavender foal syndrome
Inventor: GUTHRIE ALAN JOHN
IPC: C12Q1/68
Filed: 2010-12-01
Abstract: Disclosed is a method for detecting a genetic polymorphism associated with Lavender Foal Syndrome or a predisposition thereto in a subject, the method comprising the step of screening a genomic material sample from the subject for the presence of at least one polymorphism in a MY05A gene. Further disclosed is an isolated nucleic acid molecule selected from the group comprising a nucleic acid fragment having a sequence derived from a MY05A gene and containing the c.4459de1C polymorphism.
Patent NZ-603004-A (NZ)
Title: Assay system
Inventor: SHEPHERD PETER ROBIN
IPC: A61K9/00
Filed: 2010-04-08
Abstract: NZ 603004 Disclosed is an array including a plurality of well strips, each well strip containing a selected drug which targets a cell signalling molecule, each well strip including a plurality of wells containing a either a sequence of dilutions of the selected drug that span the EC50 of the molecular target of the drug, or the selected drug in a form capable of dilution to create a sequence of dilutions of the selected drug that span the EC50 of the molecular target of the drug, each well also including an inert gaseous environment and being sealed to contain the selected drugs in that inert environment. Also disclosed is a method of providing an array of drugs that target cell signalling molecules, the method including the steps of: selecting a plurality of drugs each of which targets a cell signalling molecule; determining a series of dilutions for each of the selected drugs that span the EC50 of the molecular target of the selected drugs; dispensing an amount of each of the selected drugs into a series of wells; transforming the amount of each of the selected drugs in the wells into a transportable form capable of reconstitution; purging the wells with a suitable gas; sealing the wells; and wherein, the amount of each of the selected drugs dispensed in the wells is such that, when the selected drugs are reconstituted, and a fixed amount of the selected drugs is transferred from each well to a series of fixed volumes of the molecular target, the final range of concentrations created spans the EC50 of the molecular target determined in step B.
Patent NZ-605324-A (NZ)
Title: Cuff for air delivery conduit
Inventor: ROW NATHAN JOHN
IPC: G05D23/24
Filed: 2009-09-01
Abstract: 605324 An air delivery conduit for use with an apparatus to deliver a supply of pressurized breathable air to a patient, comprises a tube 325 having a first end and a second end, a first cuff 330(2) for an air delivery conduit fixedly attached at the first end of the conduit, a thermistor 45 connected to at least one wire in the tube, and a second cuff 330(1) including an electrical connector 60 connected to the at least one wire to provide an electrical connection with the apparatus. The first cuff 330(2) comprises a first end portion having an internal surface fixed to an external surface of the tube of the air delivery conduit, and an external surface, and a second end portion having an internal surface of elastomeric material adapted to frictionally engage an exterior surface of a tubular connector. The internal periphery of the second end portion of the first cuff 330(2) includes an entry surface that is curved or chamfered along its length to provide a lead in for positioning the second end portion onto the tubular connector in use, the entry surface providing an internal diameter that is dimensioned to be larger than an external diameter of the tubular connector.
Patent NZ-605767-A (NZ)
Title: Process for preparing antiviral compounds
Inventor: SHEKHAR SHASHANK
IPC: C07D239/54
Filed: 2011-07-15
Abstract: Disclosed is a process for the preparation of dasabuvir (N-(6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide) or a salt thereof, wherein the process comprises: sulfonamidating 1-(3-tert-butyl-5-(6-tosyl-naphthalen-2-yl)-4-methoxyphenyl)-2,4-dioxo-3,4-dihydropyrimidine, or an analogue thereof (such as 1-(3-tert-butyl-5-(6-perfluorobutanesulfonyl-naphthalen-2-yl)-4-methoxyphenyl)-2,4-dioxo-3,4-dihydropyrimidine) with methanesulfonamide, preferably using a palladium catalyst and a phosphine ligand. Also disclosed are useful intermediates such as 1-(3-tert-butyl-5-(6-perfluorobutanesulfonyl-naphthalen-2-yl)-4-methoxyphenyl)-2,4-dioxo-3,4-dihydropyrimidine and 1-(3-tert-butyl-5-(6-hydroxy-naphthalen-2-yl)-4-methoxyphenyl)-2,4-dioxo-3,4-dihydropyrimidine.
Patent NZ-607040-A (NZ)
Title: Method for managing a degraded mode of a cell in a radiocommunication network
Inventor: ROSIN FRÉDÉRIC
IPC: H04W72/00
Filed: 2011-08-02
Abstract: Disclosed is a method for managing a degraded mode of a cell in a cellular telecommunications network. The network includes a site controller intended to control, via a packet network, a plurality of transmitters distributed on different sites of the cell. The control is performed such that the transmitters implementing the same pair of frequencies over different sites form a channel, which in dynamic mode is allocated dynamically to any communication between terminals of the cell. The channel includes a master transmitter selected by the site controller. The method comprises, in each master transmitter on detection of a failure of the site controller, the following steps: - switching of the master transmitter to degraded mode by associating with the channel a predefined communication known to the terminals, and - transmission from the master transmitter, via the packet network, of a control message informing at least one control console connected to the packet network of the implementation of the degraded mode such that the control console participates, via said packet network in a communication in progress in the channel.
Patent NZ-617140-A (NZ)
Title: Method and apparatus for authentication of a coin or other manufactured item
Inventor: TRUONG HIEU
IPC: G07D5/00
Filed: 2012-04-20
Abstract: Disclosed is a method of authenticating a coin. The method includes capturing an image of the coin using a digital camera and locating an acquisition area of the image using a landmark of the coin. The acquisition area comprises a surface feature of the coin. The surface feature comprises an imprint produced by at least one of a die, a punch, or a matrix used to manufacture the coin, wherein other coins produced by the at least one of the die, the punch, or the matrix also comprise the surface feature comprising the imprint. The method further includes generating a digital representation of the acquisition area.
Patent NZ-619023-A (NZ)
Title: Serpin fusion polypeptides and methods of use thereof
Inventor: ECKELMAN BRENDAN P
IPC: C12P21/08
Filed: 2012-06-28
Abstract: Disclosed is an isolated fusion protein comprising at least one human serpin polypeptide comprising a human alpha-1 antitrypsin (AAT) polypeptide comprising the amino acid sequence of SEQ ID NO: 1 operably linked to an immunoglobulin Fc polypeptide comprising an amino acid sequence that is at least 98% identical to the amino acid sequence of SEQ ID NO: 6, wherein the sequences are as defined in the complete specification. Also disclosed is an isolated fusion protein comprising at least one human alpha-1 antitrypsin (AAT) polypeptide comprising the amino acid sequence of SEQ ID NO: 32 or SEQ ID NO: 33 operably linked to an immunoglobulin Fc polypeptide comprising an amino acid sequence that is at least 98% identical to the amino acid sequence of SEQ ID NO: 6, wherein the sequences are as defined in the complete specification. Further disclosed is the use of said fusion proteins in the manufacture of a medicament for treating or alleviating inflammation or a symptom of an inflammatory disease or disorder while reducing the risk of infection, in a subject in need thereof.
Patent NZ-626052-A (NZ)
Title: Bridge construction kit set and method
Inventor: KELLY WRIGHT
IPC: E01D101/26
Filed: 2013-06-11
Abstract: A method and kit for constructing a bridge using hand placable parts is disclosoed. The method is disclosed as being particularly useful where access by heavy transport is limited or impossible. The method has the steps of 1) locating a first set of foundation blocks (1) on one side of an obstacle, 2) locating a second set of foundation blocks (2) on the opposite side of the obstacle, 3) connecting together an array of spanning panels (3) to form a deck (4), 4) connecting a first end of the deck to the first set of foundation blocks and connecting a second end of the deck to the second set of foundation blocks, 5) pouring a settable material over the deck. The settable material may be concrete. The foundation blocks and spanning panels are constructed to connect together. Provisional for reninforcment of the concrete layer is also made.
Patent NZ-702935-A (NZ)
Title: Process for making hydroxylated cyclopentylpyrimidine compounds
Inventor: ASKIN DAVID
IPC: C07D403/04
Filed: 2013-05-17
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
Patent NZ-709967-A (NZ)
Title: Use of phenoxypropylamine compounds to treat depression
Inventor: PELLEGRINI LORENZO
IPC: A61K31/496
Filed: 2014-01-24
Abstract: Disclosed herein are compositions and methods for treating depression using compositions comprising a compound of formula I. Disclosed herein are compositions and methods for treating depression using compositions comprising phenoxypropylamine compounds and derivatives having selective affinity for and antagonistic activity against the 5-HT1A receptor, as well as 5-HT reuptake inhibitory activity. In addition, compositions and methods for treating depression using compositions comprising a compound of formula II are disclosed. Methods of treating or diminishing at least one symptom of depression in a human subject with a composition comprising a compound of the formula (I) or formula (II), or a pharmaceutically acceptable salt, hydrate, or solvate thereof, are also disclosed.
Patent NZ-712889-A (NZ)
Title: Heterocyclic compounds useful in the treatment of disease
Inventor: BEATON GRAHAM
IPC: C07D231/10
Filed: 2014-03-17
Abstract: Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as dieases involving retinal degeneration; nerve diseases such as pruritus and pain. Non-limiting examples of those compounds include (R)-1-(4’-{ 5-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-4-fluoro-pyrazol-1-yl} -2-fluoro-biphenyl-4-yl)-cyclopropanecarboxylic acid.
Patent NZ-714911-A (NZ)
Title: Processes for preparing foam composites
Inventor: BRACEGIRDLE WREN
IPC: C08J9/35
Filed: 2014-05-07
Abstract: Processes for preparing polystyrene-phenolic foam composites and precursor compositions are described. The processes yield composites having advantageous properties particularly useful in insulation and fire resisting applications.
Patent NZ-720995-A (NZ)
Title: Pediculicidal composition
Inventor: HARDING RONALD
IPC: A61K31/444
Filed: 2014-12-17
Abstract: The present invention relates to pediculicidal compositions comprising a metal chelating agent, in particular 5,5’-dimethyl-2,2’- dipyridyl, and a carrier vehicle comprising water and an activating solvent system comprising an alcohol, such as benzyl alcohol and a hydrocarbon, such as mineral oil. The carrier vehicle may be in the form of a solution, a cream, an ointment, a foam, a spray, an emulsion or a gel. The disclosure also provides method for use of a pediculicidal composition to treat human head lice and their eggs and methods for controlling head lice infestation.