baber/WOPTO huggingface dataset:
Patent WO-2021188936-A1 (WO)
Title: Phd inhibitor compounds, compositions, and use
Inventor: FLEMING PAUL
IPC: C07D403/04
Filed: 2021-03-19
Abstract: The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof, or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatment of diseases including heart ( e.g . ischemic heart disease, congestive heart failure, and valvular heart disease), lung ( e.g ., acute lung injury, pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease), liver ( e.g . acute liver failure and liver fibrosis and cirrhosis), and kidney ( e.g . acute kidney injury and chronic kidney disease) disease.
Patent WO-2021247126-A1 (WO)
Inventor: LAI JIAN-CHENG
IPC: H01H13/7073
Filed: 2021-03-29
Abstract: Key switches of the inventive subject matter are designed to give users the tactile feel of key switches from expensive mechanical keyboards without drawback typically associated with alternative key switches. In some embodiments, key switches described in this application are designed to function with a sheet of membrane switches, while in other embodiments, key switches of the inventive subject matter incorporate optical switching in place of membrane switching. Embodiments for use with membrane switching feature a plunger and rocker combination that prevents the pressure from a user's key press from being directly transferred to a membrane switch, thereby reducing wear and tear. In optical switching embodiments, pressing the key switch causes an actuator, e.g., come between an optical emitter/ receiver pair to register a key press.
Patent WO-2021211983-A1 (WO)
Title: Systems, methods, and non-transitory computer-readable media for secure biometrically-enhanced data exchanges and data storage
Inventor: PRASZCZALEK PRZEMEK
IPC: H04L29/06
Filed: 2021-04-16
Abstract: A privacy-enhancing system, method, and non-transitory computer-readable medium for securely identifying or verifying an individual over time without retaining sensitive biometric data (e.g., biometric images or biometric templates) for the purpose of securely storing data regarding the individual.
Patent WO-2021216967-A1 (WO)
Inventor: ANCAR TERRY L
IPC: A61B6/00
Filed: 2021-04-23
Abstract: X-ray imaging systems and methods comprising, at least, an x-ray source, an x-ray detector, and a collimator assembly. The collimator assembly comprising a computer, a display, a camera, an x-ray source to object (patient) measuring device to measure source to object distance (SOD), and a plurality of metallic barriers used to manipulate a size and shape of X-ray beams, thereby also reducing the volume of irradiated tissue in the patient. The collimator may comprise computer-controlled motorized shutters to admit radiation into the region defined by the adjustable beam-defining components of the collimator of an X-ray apparatus. In some embodiments, the plurality of metallic barriers may be a fixed cone, or a cone comprised of movable plates.
Patent WO-2021222224-A1 (WO)
Inventor: PUDIYAPURA AJEER SALIL
IPC: H04L45/748
Filed: 2021-04-27
Abstract: Described are programmable IO devices comprising: an MPU and a memory unit. The MPU comprising at least one ALU. The memory unit having instructions stored thereon which, when executed by the respective programmable IO device, cause the programmable IO device to perform operations. These operations comprise: receiving, from an inbound interface, a packet comprising packet data for at least one range-based element; determining, via the MPU, a lookup result by performing a modified binary search on an interval binary search tree with the packet data to determine a LPM, wherein the interval binary search tree maps the at least one range-based element to an associated data element; and classifying the packet based on the lookup result.
Patent WO-2021225992-A1 (WO)
Title: Core retention compression clamp and method of installation
Inventor: MORRIS RONALD
IPC: H01B12/06
Filed: 2021-05-03
Abstract: A core retention clamp that is an elongated member having a bore extending therethrough and an outer surface. The core retention clamp can be utilized with an installation system to install an electrical conductor having a composite core surrounded by a stranded conductor. The core retention clamp facilitates the coupling of the pulling grip with the composite core so that relative movement of the composite core and the stranded conductor is minimized.
Patent WO-2022005597-A1 (WO)
Title: Coordinated multi-viewpoint image capture
Inventor: BATHIJA JAYESH
IPC: H04N5/262
Filed: 2021-05-04
Abstract: Various embodiments may include methods and systems for configuring synchronous multi-viewpoint photography. Various embodiments may include displaying preview images on initiating and responding devices. Various embodiments may include determining an adjustment to the orientation of a responding device based on the preview images. Various embodiments may include transmitting an instruction configured to enable the responding device to display a notification for adjusting the position or the orientation of the responding device based at least on the adjustment. Various embodiments may include transmitting, to the responding device, a second instruction to enable the responding device to capture a second image at approximately the same time as the initiating device captures a first image. Embodiments further include capturing, via a camera, the first image, receiving, from the responding device, s second image, and generating an image file based on the first image and the second image.
Patent WO-2021231611-A1 (WO)
Title: Methods for treating cancer using spl-108 polypeptide based on tp53 mutational status
Inventor: FINLAYSON MALCOLM
IPC: C07K16/28
Filed: 2021-05-12
Abstract: The present invention relates to methods of treatment for cancer using SPL-108 polypeptide (also known as A6 peptide or A6, a CD44 modulating peptide; FIG. 1; SEQ ID NO:1) based on the TP53 status of the cancer. In particular, this invention relates to such methods of treatment by using TP53 mutational status to guide the administration of an SPL-108 polypeptide or a variant thereof alone or in combination with a standard-of-care treatment for patients with cancer. TP53 mutational status is used to select patients that may or may not respond to SPL-108 polypeptide or a variant thereof; specific mutations TP53 predict the response of patients including progressive disease, stable disease, and/or partial/complete response to SPL-108. Such methods of the present invention are used to treat cancer to alleviate and/or prevent symptoms of cancer, and/or to avoid side effects commonly associated with treating cancer.
Patent WO-2021242795-A1 (WO)
Title: Attenuated post-metallocene catalysts
Inventor: NEILSON BETHANY M
IPC: C08F110/14
Filed: 2021-05-26
Abstract: A method of making an attenuated-light-off post-metallocene catalyst, the method comprising combining a faster-light-off catalyst with an effective amount of a kinetics modifier compound of formula (A 1 ), (B 1 ), or (C 1 ): R5-C≡C-R 6  (A 1 ), (R 5 ) 2 C=C=C(R 6 ) 2  (B 1 ), or (R 5 )(R 7 )C=C(R 6 )(R 7 ) (C 1 ) as defined herein under effective reaction conditions to give an attenuated post-metallocene catalyst that exhibits an attenuated light-off monomer uptake profile (relative to that of the faster-light-off catalyst); wherein the faster-light-off catalyst has been made by activating a post-metallocene precatalyst of structural formula (I) as defined herein; and related methods, compositions and uses.
Patent WO-2021257367-A1 (WO)
Title: Dual lidar sensor for annotated point cloud generation
Inventor: LI HAO
IPC: G01S7/48
Filed: 2021-06-10
Abstract: According to one aspect, a sensor system of an autonomous vehicle includes at least two lidar units or sensors. A first lidar unit, which may be a three-dimensional time of flight (ToF) lidar sensor, is arranged to obtain three-dimensional point data relating to a sensed object, and a second lidar unit, which may be a two-dimensional coherent or frequency modulated continuous wave (FMCW) lidar sensor, is arranged to obtain velocity data relating to the sensed object. The data from the first and second lidar units may be effectively correlated such that a point cloud may be generated that includes point data and annotated velocities.
Patent WO-2021262625-A1 (WO)
Inventor: SLEYTR UWE
IPC: C07K17/14
Filed: 2021-06-22
Abstract: Described are S-layer fusion proteins comprising a self-assembling domain of a S- layer protein and a viral spike protein or a fragment thereof, a pharmaceutical composition (such as a vaccine) comprising the S-layer fusion protein, and method of immunizing a patient in need thereof comprising administering the vaccine.
Patent WO-2022015479-A1 (WO)
Title: Specimen collection and storage for pool testing and similar
Inventor: KOTANKO PETER
IPC: A61B10/02
Filed: 2021-06-24
Abstract: The present teachings generally include devices, systems, kits, and methods for collecting, storing, and transporting specimens, e.g., in the context of pool testing. For example, the present teachings may include a compound swab featuring a first swab and a second swab, where the first swab can be detached for pool testing and the second swab can be preserved for testing based on results of the pool test. The present teachings may also or instead include a container having a separator structurally configured to separate swabs of a compound swab. Further, the present teachings may include a swab having a suction enhancer to promote the capture of a specimen on a collection tip thereof. The present teachings may also or instead include a receptacle that can house a plurality of swabs and sever at least a portion of the collections tips thereof, e.g., for pool testing.
Patent WO-2022046902-A1 (WO)
Title: Breath collector and method for diagnosis and/or monitoring
Inventor: STROME SCOTT
IPC: G01N33/497
Filed: 2021-08-25
Abstract: A device for capturing exhaled breath of an individual for diagnosis, monitoring, and/or study of conditions and/or diseases comprises a mouthpiece; a mixing chamber, to which the mouthpiece is connected; an exhaust tube connected to the mixing chamber, the exhaust tube having an outlet formed therein; and a container having a capture material disposed therein. The mixing chamber is formed such that the exhaled breath from the individual, which is introduced therein via the mouthpiece, contacts the capture material and traps an exhalant of interest in and/or on the capture material.
Patent WO-2022055908-A1 (WO)
Inventor: ZHANG SIMENG
IPC: A61N1/36
Filed: 2021-09-08
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
Patent WO-2022066412-A1 (WO)
Title: Method and device for presenting content based on machine-readable content and object type
IPC: G06Q30/02
Filed: 2021-09-08
Abstract: In one implementation, a method of presenting virtual content is performed by a device including an image sensor, one or more processors, and non-transitory memory. The method includes obtaining, using the image sensor, an image of a physical environment. The method includes detecting, in the image of the physical environment, machine-readable content associated with an object. The method includes determining an object type of the object. The method includes obtaining virtual content based on a search query creating using the machine-readable content and the object type. The method includes displaying the virtual content.
Patent WO-2022066530-A1 (WO)
Inventor: VAN DE HEY JOSEPH F
IPC: B65H18/16
Filed: 2021-09-17
Abstract: A variable roll cage machine and process to roll up material, like high expansion force material. The machine includes a roll chamber to receive the material. The roll chamber has a longitudinal central axis and a plurality of rollers located around a circumference of the roll chamber. The plurality of rollers include two roll groups of at least two rollers in each roll group. At least one of the rollers in each roll group is movable toward the longitudinal central axis independent of at least one other roller in the roll group. A material infeed gap is in the circumference of the roll chamber located between the two roll groups and spaced from the at least one of the rollers in each roll group that is movable.
Patent WO-2022067124-A1 (WO)
Title: Fluid container with check valve
Inventor: STACK STEVEN MICHAEL JR
IPC: F16K15/20
Filed: 2021-09-24
Abstract: A fluid container has a first and second flexible membrane forming at least one chamber, a channel configured to receive pressurized inert gas, and one or more check valve assemblies disposed therebetween. The one or more check valve assemblies is formed from a continuous third flexible membrane folded at an apex, and configured to provide the flow of pressurized fluid in one direction upon inflation, from the channel to the at least one chamber, while restricting flow in the opposite direction. The one or more check valve assemblies are characterized in that they do not require pre-printing or electronic registering, thus allowing for an inflation flow rate of at least twice that of conventional inflatable packaging systems.
Patent WO-2022067201-A1 (WO)
Title: Amplifier linearization using magnetically coupled feedback provided by a transformer coupled to a balun-based load
Inventor: Fard Ali
IPC: H03F1/34
Filed: 2021-09-27
Abstract: An amplifier circuit (100) includes an amplifier (102) and a transformer having a primary winding (112) in series with an amplifier output (106) and a secondary winding (108) coupled to an amplifier input (104). The primary winding (112) and the secondary winding (108) are arranged such that a portion of a magnetic field generated by the primary winding (112) couples to the secondary winding (108) through a magnetically coupled feedback loop, thereby providing feedback from the amplifier output (106) to the amplifier input (104). An output load arrangement (120) is connected to the primary winding (112) wherein the output arrangement includes a balun (122). The amplifier circuit (100) may be implemented as an integrated circuit and where the primary (112) and secondary (108) windings are integrated in different metal layers of the integrated circuit.
Patent WO-2023059327-A1 (WO)
Inventor: PANSHIN STEPHEN
IPC: G06F21/44
Filed: 2021-10-07
Abstract: A logic circuitry package includes a logic circuit and an interface to communicate with a host logic circuit. The logic circuit includes a memory arrangement storing an asymmetric key, and/or a certificate corresponding to the asymmetric key. The logic circuit is configured to transmit, to the host logic circuit, the certificate; receive, from the host logic circuit, a static signature request comprising challenge data; and/or, transmit, to the host logic circuit, a signature computed based on the challenge data and the asymmetric key in response to the static signature request.
Patent WO-2022087298-A1 (WO)
Title: Dispositif de commande de marche volitionnelle
Inventor: Mendez Joel
IPC: A61F2/72
Filed: 2021-10-21
Abstract: La présente invention concerne une prothèse motorisée destinée à fournir une commande volitionnelle de la flexion du genou pendant l'oscillation qui est configurée pour (i) déterminer qu'une phase d'oscillation a commencé, (ii) obtenir un angle de cuisse sur la base des données de capteur associées à un membre résiduel d'un utilisateur, (iii) sur la base d'un temps écoulé depuis de le début de la phase d'oscillation, et sur la base de l'angle de cuisse, déterminer un angle maximal de flexion du genou souhaité, (iv) pendant la phase d'oscillation, mettre à jour en continu l'angle maximal de flexion du genou souhaité à l'aide de mesures ultérieures d'angle de cuisse et du temps écoulé depuis de le début de la phase d'oscillation, et (v) émettre un signal configuré pour provoquer l'actionnement de l'articulation du genou sur la base de l'angle maximal de flexion du genou souhaité.
Patent WO-2022139958-A1 (WO)
Inventor: DUAN WEIMIN
IPC: G01S5/00
Filed: 2021-11-01
Abstract: Position determination for a target user equipment (UE) uses a single base station and a plurality of sidelink UEs with known locations. The base station sends a reference signal to the target UE and sidelink UEs, and the target UE sends sidelink signals to each sidelink UEs. A range-sum for the range between the target UE and sidelink UE and the range between the sidelink UE and the base station can be determined for each sidelink UE, based on the time differences between the reception and transmissions of the reference signals measured by the target UE, and the time difference between reception of the reference signals measured by the sidelink UE. A differential in the range-sums can be determined and used to determine the position of the target UE.
Patent WO-2022099174-A1 (WO)
Inventor: XIANG CHENGXIANG
IPC: B01D53/04
Filed: 2021-11-09
Abstract: L'invention concerne des systèmes électrochimiques qui comprennent un électrodialyseur et une cellule de réduction (CO 2 R) de CO 2  alimentée par la vapeur pour capturer et convertir le CO 2  provenant de l'eau de l'océan. L'électrodialyseur comprend un empilement de cellules d'électrodialyse à membrane bipolaire (BPMED) entre des électrodes d'extrémité. L'électrodialyseur incorpore des membranes échangeuses de cations monovalents (M-CEM) qui empêchent le transfert de cations multivalents entre des compartiments de cellule adjacents, permettant une recirculation continue d'électrolytes et de solutions et fournissant ainsi un système d'électrodialyse plus sûr et présentant moins d'incrustations. Dans certains modes de réalisation, l'électrodialyseur peut être conçu pour remplacer la réaction de dissociation de l'eau au niveau d'électrodes d'extrémité avec des couples redox réversibles à un électron en solution au niveau des électrodes. Par conséquent, dans la totalité de l'empilement de l'électrodialyseur, il ne se produit pas de réactions de formation de liaison, de rupture de liaison et pas de génération de gaz, ce qui simplifie significativement la conception de la cellule et améliore la sécurité de fonctionnement. Les systèmes fournissent une voie technologique unique pour la capture et la conversion de CO 2  provenant de l'eau de l'océan, uniquement à l'aide de procédés électrochimiques.
Patent WO-2022260706-A1 (WO)
Title: Cell sector transmission system
Inventor: KANG KANG
IPC: H04B17/00
Filed: 2021-12-14
Abstract: A method includes simulating, using processing circuitry, one or more sector antenna transmitting at a selected transmission power, each of the one or more sector antenna simulated as being located at a desired physical location. The method also includes determining, based on results of the simulation, a short-term interference and a long-term interference for each of the one or more sector antenna. The method also includes performing, by the processing circuitry and based on a short-term interference threshold and a long-term interference threshold for the one or more sector antenna, one or more of: increasing the selected transmission power for one of the one or more sector antenna, decreasing the selected transmission power for the one of the one or more sector antenna, or maintaining the selected transmission power for the one of the one or more sector antenna.
Patent WO-2023069121-A1 (WO)
Title: System and method for auto-mining of resources, building dependency registry and notifying impacted services
Inventor: SASIKUMAR KRISHNAN
IPC: H04L29/06
Filed: 2021-12-15
Abstract: A method for providing dependency registration and impacted service notification is provided. The method includes mining resource data for a plurality of resources included in heterogeneous platforms included in a single eco-system, and identifying, for each resource, one or more connections with other resources present in the heterogeneous platforms based on the mined resource data. The method also includes generating a resource dependency chain from the resource data and the identified one or more connections, and monitoring change events for the resources included in the heterogeneous planforms. When a change event is detected for a target resource among the resources, the method includes determining one or more resources that are impacted by the change event detected for the target resource based on the resource dependency chain, and transmitting a notification to users of the impacted resources.
Patent WO-2022146781-A1 (WO)
Inventor: DEWALL JEFFREY MICHAEL
IPC: H04N9/31
Filed: 2021-12-21
Abstract: A method for configuring a digital light projector (DLP) of an augmented reality (AR) display device is described. A light source component of the DLP projector is configured to generate a single red-green-blue color sequence repetition per image frame. The AR display device identifies a color sequence of the light source component of the DLP projector and tracks a motion of the AR display device. The AR display device adjusts an operation of the DLP projector based on the single red-green-blue color sequence repetition, the color sequence of the light source component of the DLP projector, and the motion of the AR display device.
Patent WO-2022020847-A1 (WO)
Title: Systems and methods for detecting divergence in an adaptive system
Inventor: FARAHBAKHSH SIAMAK
IPC: G10K11/178
Filed: 2021-07-20
Abstract: Detecting a divergence in an adaptive system includes the steps of determining a power of a component of an error signal at a first frequency, the component being correlated to a noise-cancellation signal, the noise-cancellation signal being produced by an adaptive filter and being configured to cancel noise within a predetermined volume when transduced into acoustic signal, wherein the error signal represents a magnitude of a residual noise within the predetermined volume; determining a time gradient of the power of the component of the error signal; and comparing a metric to a threshold, wherein the metric is based, at least in part, on a value of the time gradient of the power of the component of the error signal over a period of time.
Patent WO-2022120373-A1 (WO)
Title: Trem2 agonist biomarkers and methods of use thereof
Inventor: ELLWANGER DANIEL C
IPC: C07K16/28
Filed: 2021-12-03
Abstract: The present invention provides a method of treating a disease or conditions associated with a dysfunction of TREM2 in a human patient, such as Alzheimer's disease, comprising administering to the patient a TREM2 agonist. In another aspect, the invention provides a method of assaying a biological sample taken from a patient having Alzheimer's for biomarkers to determine potential benefit or if the disease has an increased probability of responding to treatment with a TREM2 agonist.
Patent WO-2022133448-A1 (WO)
Title: Structure de réseau de composants empilés
Inventor: ZHAO JIN
IPC: H05K3/34
Filed: 2021-12-14
Abstract: L'invention concerne une structure dotée d'un réseau de composants électroniques positionnée entre deux cartes de circuits imprimés empilées (600, 606). Les composants électroniques (502) du réseau peuvent être connectés à la carte de circuit imprimé (600, 606) par l'intermédiaire de connexions par soudure. Des exemples de composants électroniques (502) comprennent des condensateurs. Des procédés de fabrication connexes sont divulgués qui impliquent l'application de chaleur à un réseau de pâte à braser sur une carte de circuit imprimé (600, 606) pour constituer des conducteurs solides connectés électriquement aux composants électroniques (502).