baber/WOPTO huggingface dataset:
Patent EA-003191-B1 (EA)
Title: A crystalline form calcuim (3s) tetrahydro-3-furanyl(1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobbutyl)amino]-1-benzyl-2-(phosphonooxy)propylcarbamate
Inventor: ARMITAGE IAN GORDON
IPC: C07F9/00
Filed: 1999-07-15
Abstract: 1. A crystalline form of calcium (3S) tetrahydro-3-furanyl(1S,2R)-3-[[(4-aminophenyl) sulfonyl](isobutyl)amino]-1 -benzyl-2-(phosphonooxy)propylcarbamate characterized by an X-ray powder diffraction trace substantially as shown in FIG. 1, wherein said powder diffraction pattern is obtained with help of diffractometer using cupric K alpha-irradiation source. 2. A crystalline form of calcium (3S) tetrahydro-3-furanyl(1S,2R)-3-[[(4-aminophenyl) sulfonyl](isobutyl)amino]-1 -benzyl-2-phosphonooxy)propylcarbamate characterized by an X-ray powder diffraction pattern expressed in terms of 2 theta angles, and obtained with help of diffractometer using cupric K alpha-irradiation source wherein said X-ray powder diffraction pattern has peaks that may occur at the following approximate 2 theta angles: 5.735, 9.945, 11.500, 13.780, 14.930, 15.225, 17.980, 19.745, 21.575, 22.170, 24.505 and 27.020 degrees. 3. A crystalline form of calcium (3S) tetrahydro-3-furanyl(1S,2R)-3-[[(4-aminophenyl)sulfonyl] (isobutyl)amino]-1 -benzyl-2-(phosphonooxy)propylcarbamate characterised by an X-ray powder diffraction pattern expressed in terms of 2 theta angles and relative intensities (1), and obtained with help of diffractometer using cupric K alpha-irradiation source: 2 theta angle  Rel. int-ty 5.7350  100 9.9450  38 11.1150  7 11.5000  10 13.7800  18 14.9300  10 15.2250  16 17.9800  35 19.7450  14 19.9600  5 20.8050  8 21.5750  12 22.1700  15 22.3550  7 22.9100  6 23.1350  5 24.5050  14 25.0350  2 25.2550  2 25.8600  7 26.5050  2 27.0200  10 27.7850  3 28.2150  4 28.3650  6 28.8250  2 28.9450  2 29.4150  4 30.1950  2 30.5750  3 31.1200  2 31.7950  2 32.2450  4 32.7750  3 32.8900  3 33.8150  2 34.9050  2 35.2950  3 35.8050  2 36.4600  3 36.8300  2 37.8400  2 38.6550  2 39.5350  2 39.6150  2 40.5850  3 41.3550  2 41.8100  2 42.2350  2 42.6900  3 43.2000  2 43.9200  1 44.4000  2 4. A pharmaceutical composition comprising crystalline compound according to any of claims 1-3 together with, at least, one pharmaceutical acceptable diluent or carrier. 5. A process for the preparation of a compound of formula (I), comprising I) reacting a compound of formula (II) with a phosphorylating agent; II) reducing the resultant compound with a reducing agent in a suitable solvent; and III) adding to the resultant compound a source of calcium ions in the presence of a suitable solvent. 6. A process for the preparation of a compound of formula (I) comprising dissolving a compound of formula (III) in a suitable solvent, and adding to the solution water and a source of calcium ions. 7. A process for the preparation of a compound of formula (I) comprising the reduction of a compound of formula (IV) in the presence of a suitable reducing agent in a suitable solvent, followed by adding water and a source of calcium ions.
Patent EA-003722-B1 (EA)
Title: Hydraulic ram
IPC: F04F7/02
Filed: 2001-11-16
Abstract: 1. Hydraulic ram, containing feed pipeline with chamber, which is its continuation, having round form of cross-section of similar diameter, placed on the end part and provided above with plane supporting saddle of pressure valve, and impact valve and mating with it sloped supporting saddle are made in form of ellipse, characterized in that the supporting saddle of pressure valve is placed over alimenting pipeline and connected centrically with it by means of short nipple with the diameter, which is bigger than the diameter of discharge line, and a check valve, provided with adjustable closing level stopper is placed at the entry of feed line.
Patent EA-009394-B1 (EA)
Title: PROCESS FOR THE PREPARATION OF MONOSUBSTITUTED β-AMINO ALCOHOLS
Inventor: MICHEL DOMINIQUE
IPC: C07C221/00
Filed: 2003-07-09
Abstract: The invention relates to a process for the synthesis of N-monosubstituted beta-amino alcohols of formula (I) and/or an addition salt of a proton acid, wherein Rand Rindependently represent Calkyl, Ccycloalkyl, phenyl, naphthyl, furanyl, benzofuranyl, thienyl, benzo [b] thienyl and aralkyl, wherein the alkyl moiety of the aralkyl residue is linear Calkyl, and the aryl moiety is selected from the group consisting of phenyl, naphthyl, furanyl, benzofuranyl, thienyl and benzo [b] thienyl, each aryl or aralkyl being optionally substituted with halogen, linear or branched Calkyl, linear or branched Calkoxy, Ccycloalkyl, CF, CF, OCFor OCF, via direct preparation of N-monosubstituted beta-amino ketones of said formula and its addition salts of proton acids, wherein Rand Rare as defined above.
Patent EA-007036-B1 (EA)
Title: Device for organising mass distraction
Inventor: GAVRILOV SERGEY ANATOLIEVICH
IPC: G06Q99/00
Filed: 2003-03-28
Abstract: The invention relates to a device for organising mass distraction. The essence of the invention lies in that subscriber terminals are embodied in the form of different-type terminals. The inventive device comprises a central station for registration of subscribers and the terminals thereof and for making it possible for the subscribers to interact with the station and therebetween through the station in order to create the anonymity thereof.
Patent EA-009792-B1 (EA)
Title: Process for improving the co-polymerization of ethylene and an olefin co-monomer in a polymerization loop reactor
Inventor: DAMME ERIC
IPC: C08F210/16
Filed: 2005-02-14
Abstract: The present invention relates to a process for improving the co -polymerization of ethylene and an olefin co -monomer, preferably hexene, in a polymerization loop reactor characterized in that said process comprises the step of controlling the co -monomer/monomer ratio along the path of the reactor, and in particular by multiple, spat Tally separated, feeding of monomer along the path of the loop reactor. In another aspect, the invention relates to a polymerization loop reactor suitable for the co -polymerization process of ethylene and an olefin co -monomer, preferably hexene.
Patent EA-011974-B1 (EA)
Title: Pretreatment process an apparatus for solid lump feed material
Inventor: POTTER STEPHEN M
IPC: C21B13/00
Filed: 2004-03-12
Abstract: A pretreatment process for solid lump feed material for a gas and pellet/lumpbased direct reduction process, comprising preheating feed material to a temperature of from about 200°C to about 500°C, without reduction, in a non-reducing atmosphere prior to charging the feed material to gas-based direct reduction furnace, thereby minimizing the formation of fines within the furnace. The invention also relates to an apparatus for preheating feed material.
Patent EA-013075-B1 (EA)
Title: Safeners used to increase herbicidal action of fungicides and fungicidal agent
Inventor: FISCHER REINER
IPC: A01N43/56
Filed: 2005-09-29
Abstract: The invention relates to safeners for herbicides, used to increase the microbicidal action of fungicides, the safener is selected from the group comprising isoxadifen, isoxadifen-ethyl, mefenpyr and mefenpryrdiethyl and the fungicide is selected from the group consisting of prothioconazole, tebuconazole, fluoxastrobin, trifloxystrobin and spiroxamine and N-(3',4'-dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide. There also described a fungicidal agent comprising above mentioned safener and fungicide. The invention provides to obtain a synergetic effect.
Patent EA-014083-B1 (EA)
Title: Novel indole carboxamide derivatives, a pharmaceutical composition comprising thereof and a method for treating thereof
Inventor: DENG JIANGHE
IPC: A61K31/404
Filed: 2006-06-28
Abstract: The invention is directed to novel indole carboxamide derivatives. Specifically, the invention is directed to compounds according to formula I: Formula (I)where R1 , R2, R3, U and V are defined below and to pharmaceutically acceptable salts thereof. The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, such as rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease). Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting IKK2 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
Patent EA-012711-B1 (EA)
Title: Method and device for charging processing plants
Inventor: HIMMELFREUNDPOINTNER KURT
IPC: F23K5/04
Filed: 2006-09-25
Abstract: A device and method for charging processing plants, in particular, combustion furnaces (1), is disclosed, in which a flowing process material (3), which has solid components (6) in addition to liquid components (5), is introduced into the processing plant (1), by means of a conveyor line (2) under pressure. According to the invention, advantageous charging conditions may be achieved, by means of mixing the process material (3) before pressurisation.
Patent EA-013756-B1 (EA)
Title: Process for isolation of an organic amine
Inventor: PETERS ALEXANDER VOLKER
IPC: C07C209/86
Filed: 2006-12-20
Abstract: The invention relates to a process for the isolation of an organic amine from a composition comprising the organic amine and an acid, or a salt of the organic amine and the acid, wherein the process comprises steps wherein ammonia or hydrazine is added to the composition thereby forming a multi-phase system comprising an organic amine -rich phase and an acid-rich phase, the organic amine-rich phase and the acid-rich phase obtained in step (i) are separated, and the organic amine is isolated from the organic amine -rich phase.
Patent EA-015438-B1 (EA)
Title: Novel oxidoreductases and uses thereof
Inventor: MUTSAERS JOHANNA HENRICA GERDINA MARIA
IPC: A21D8/04
Filed: 2007-02-06
Abstract: The invention relates to newly identified polynucleotide sequences comprising a gene that encodes a novel oxidoreductase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel oxidoreductase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in baking and in dairy applications. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a oxidoreductase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
Patent EA-016593-B1 (EA)
Title: Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a ph control agent
Inventor: YONEYAMA SHUJI
IPC: A61K9/16
Filed: 2008-03-26
Abstract: The present invention provides a solid pharmaceutical composition containing is (5-methyl-2-oxo-1,3-dioxol-4-yl) methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate potassium salt. Compound (I) having an angiotensin II receptor antagonistic action and defined in the specification and a pH control agent, which composition is superior in the stability and dissolution property of compound (I).
Patent EA-017718-B1 (EA)
Title: New polymorphic forms of n-[4-(trifluoromethyl)benzyl]-4-methoxybutyramide
Inventor: CACCIAGLIA ROBERTO
IPC: A61K31/165
Filed: 2008-11-12
Abstract: Crystalline polymorphic forms of a compound of formula N-[4-(trifluoromethyl)benzyl]-4-methoxybutyramide are described. The two polymorphic forms, named polymorphic Form A and polymorphic Form B, can be used in the treatment of drug addiction and alcoholism and have very good stability. Methods for preparing the polymorphic forms are also described.
Patent EA-020657-B1 (EA)
Title: Tailored multi-site combinatorial assembly
Inventor: TAN XUQIU
IPC: C12P19/34
Filed: 2008-07-31
Abstract: The present invention provides a novel method of producing a plurality of modified polynucleotides having different combinations of various mutations at multiple sites by a tailored multi-site combinatorial assembly, comprising adding at least two or at least three primers to a double stranded template polynucleotide in a single reaction mixture, wherein the primers are not overlapping, and wherein each of the primers comprise at least one mutation different from the other primers, wherein at least one primer is a forward primer that can anneal to a minus strand of the template and at least one primer is a reverse primer that can anneal to a plus strand of the template, and subjecting the reaction mixture to a polymerase extension reaction to yield a plurality of extended modified polynucleotides from the at least three primers. The method can be performed without employing a ligation step prior to transforming the extended modified polynucleotides into a cell. The plurality of extended modified polynucleotides can be treated with an enzyme for destroying the template polynucleotide prior to transforming in to the cell.
Patent EA-027249-B1 (EA)
Title: Detector for detecting a gravity gradient
Inventor: VAN KANN FRANK JOACHIM
IPC: G01V7/02
Filed: 2009-09-25
Abstract: The present disclosure provides a gravity gradiometer for detecting a gravity gradient. The gravity gradiometer comprises at least two sensor masses that are pivotable about respective axes and that experience a change in torque in response to a change in gravity gradient whereby the at least two sensor masses move relative to each other in response to the change in gravity gradient and wherein a signal indicative of the gravity gradient is generated in response to the relative movement of the at least two sensor masses. Further, the gravity gradiometer comprises an acceleration sensor for sensing an acceleration associated with an external acceleration applied to the gravity gradiometer. The gravity gradiometer also comprises an actuator for generating an adjustment force that is dependent on an acceleration sensed by the acceleration senor. The adjustment force is also dependent on a mechanical response parameter associated with at least one of the at least two sensor masses. The adjustment force is applied such that a difference between the magnitudes of the torques experienced by the at least two sensor masses in response to the change in gravity gradient is reduced.
Patent EA-030476-B1 (EA)
Title: Untreated oil produced from mortierella alpina, and food product containing same
Inventor: SCHAAP ALBERT
IPC: A23L33/00
Filed: 2003-06-20
Abstract: The pr invention provides untreated oil, comprising at least 35% of arachidonic acid (ARA) and having the anisidine number (AnV) less than 25 and peroxide number (POV) not more than 3.0, produced by heating Mortierella Alpina at temperature of 40 to 60°C during not more than 30 min at a rate of at least 0.5°C/min. The invention also provides a food product and/or a food additive, comprising the claimed oil, which can be used as a mixture for baby food or feed product or feed additive for animals, in particular marine animals.
Patent EA-020493-B1 (EA)
Title: Sulphur cement product
Inventor: VERBIST GUY IODE MAGDA MARIA
IPC: C04B28/36
Filed: 2010-05-18
Abstract: A sulphur cement product comprising from 10 to 30 wt% of sulphur, 70 to 90 wt% of particulate inorganic material and from 0.4 to 2 wt% of wax, and comprising less than 5 wt% of bitumen, wherein the weight percentages are based upon the weight of the sulphur cement product, is disclosed. Further disclosed is a process for preparing a sulphur cement product; a process for preparing a sulphur cement surfacing on a structural material; and use of a wax to improve the fouling deposit removal and/or graffiti removal properties of a sulphur cement product.
Patent EA-022844-B1 (EA)
Title: Method for emergency plugging of a well with an undersea arrangement of the head and apparatus for carrying out said method (variants)
Inventor: MATSUR IGOR YURIEVICH
IPC: E21B33/10
Filed: 2011-05-11
Abstract: The invention relates to the oil-and-gas-extracting industry and can be used for emergency plugging of wells. The method for emergency plugging of a well with an undersea arrangement of the head comprises pumping in a cementing composition, wherein, first of all, the cementing depth of the well section is defined on the basis of the condition of the well and pressure therein, an injector, which is fastened to a tank containing the cementing composition and is arranged within a sack of flexible material, is lowered to the bottom and introduced into the emergency well head to the specified depth, the sack is filled with the cementing composition, the latter being pumped into the sack from the tank via the injector, ensuring tight contact of the external surface of the sack with the internal surface of the well, wherein the injector is secured at the specified depth on account of the weight of the entire structure filled with the cementing composition, and, after the pumping-in operation, pressure is maintained in the sack until the cementing composition has solidified. After the cementing composition has solidified, either fluid is pumped out or the well is plugged.
Patent EA-024966-B1 (EA)
Title: Method and system for tunnel ventilation in normal conditions and in conditions of fire
Inventor: PAVETIC JOSIP
IPC: E21F1/08
Filed: 2010-07-27
Abstract: Tunnel ventilation system providing a horizontal partition (1) divided into three separate ventilation ducts (4 and 5) with fire-resistant flaps which in an emergency hermetically close the ventilation ducts. Their position is controlled in dependence on measured parameters in the tunnel and whether or not there is fire in the tunnel and, if there is, the position of fire. Fans (3, 3a) are operated in dependence on conditions prevailing in the tunnel. An air screen (6a) prevents the influx of air in excess of the designed quantity from the environment into the tunnel. The system incorporates a tube-shaped tank (9) positioned longitudinally under the carriageway that contains air with reduced oxygen content in quantity sufficient for fire fighting. In the event of fire, air with reduced oxygen content is brought into the space of the tunnel's fire section.
Patent EA-024716-B1 (EA)
Title: 5-(3-aminophenyl)-5-alkyl-5,6-dihydro-2h-[1,4]oxazin-3-amine derivatives
Inventor: GIJSEN HENRICUS JACOBUS MARIA
IPC: C07D413/12
Filed: 2012-12-04
Abstract: The present invention relates to novel 5-(3-aminophenyl)-5-alkyl-5,6-dihydro-2H-[1,4]oxazin-3-amine derivatives of formula (I)where the meanings of derivatives Rand Ar are defined in the claims, as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The present invention also relates to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, cerebral amyloid angiopathy, multi-infarct dementia, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease and dementia associated with beta-amyloid.
Patent EA-025937-B1 (EA)
Title: Steel for oil country tubular goods and method of producing the same
Inventor: OMURA TOMOHIKO
IPC: C22C38/00
Filed: 2013-06-17
Abstract: A steel for oil country tubular goods includes, as a chemical composition, by mass %, C, Si, Mn, Al, Mo, P, S, O, N, and a balance containing Fe and impurities, wherein a full width at half maximum HW of a crystal plane corresponding to a (211) crystal plane of an α phase and a carbon content expressed in mass % in the chemical composition satisfy HW×C≤0.38, the carbon content and a molybdenum content expressed in mass % in the chemical composition satisfy C×Mo≥0.6, a number of MC carbides having a hexagonal crystal structure and having an equivalent circle diameter of 1 nm or more is 5 pieces or more per one square micron, and an yield strength is 758 MPa or more.
Patent EA-027188-B1 (EA)
Title: Method for purification of water using capacitive deionisation
Inventor: GHOSH SOMNATH
IPC: C02F1/469
Filed: 2013-06-11
Abstract: Disclosed is a method of deionising water by capacitive deionisation comprising repeating series of cycles during which water is passed through at least one pair of oppositely charged electrodes, each cycle comprising: (i) a charging step; (ii) a first short-circuiting step; (iii) a discharging step consisting of reversal of the applied charge on the electrodes; and (iv) a second short-circuiting step, wherein polarity applied to each electrode in each pair of oppositely charged electrodes during said charging step of a given series of repeating cycles is reversed during the charging step of the immediately following series of repeating cycles and wherein each said series comprises 10 to 20 cycles.
Patent EA-028603-B1 (EA)
Title: Method for measuring composition of sample
Inventor: LABUSOV VLADIMIR ALEKSANDROVICH
IPC: G01N21/17
Filed: 2014-04-24
Abstract: The invention relates to the field of analytical instrument construction and specifically to an absorption spectral analysis, and can be used in creating automated monitoring posts, for instance for monitoring mine gases in mines, and for the ecological monitoring of the gas emissions or industrial wastewater of enterprises. Claimed is a method for measuring the composition of a sample, including registering a calibration spectrum, registering an operating spectrum for sample transmission and for computing, using calibration dependences, the concentrations of components to be determined. The method is novel in that both spectra are recorded without changing the length of the optical path of light through a sample, however, at the same time, a sample transmission spectrum is used as the calibration spectrum, said sample transmission spectrum being registered by a spectrometer with an entrance slit having a spectral width which exceeds the width of a registered absorption line of a component to be determined in the operating spectrum of sample transmission, the registration of which is carried out with a slit width allowing for measuring the intensity of the absorption line of the component to be determined, and the registration of the said spectra is carried out using a multi-element solid state detector, and one or more emitters with smooth spectrum distribution are used as the source of radiation.
Patent EA-030978-B1 (EA)
Title: Pane having an electrical connection element
Inventor: SCHMALBUCH KLAUS
IPC: H05B3/84
Filed: 2013-07-10
Abstract: The present invention relates to a pane having at least one electrical connection element, said pane comprising a substrate (1), an electrically conductive structure (2) in a region of the substrate (1), a connection element (3) in a region of the electrically conductive structure (2), said connection element containing at least a chromium-containing steel, wherein the connection element (3) has a region which is crimped about a connecting cable (5), the crimped region of the connection element (3) being connected to the electrically conductive structure (2) by means of a solder (4).
Patent EA-030905-B1 (EA)
Title: Industrial process for the synthesis of ulipristal acetate and its 4'-acetyl analogue
Inventor: MAHO SANDOR
IPC: C07J51/00
Filed: 2014-10-01
Abstract: The present invention relates to a new process for the synthesis of compounds of formula (I)(wherein the meaning of R is dimethylamino or acetyl group) using compounds of formula (II)(wherein the meaning of R is dimethylamino or 2-methyl-1,3-dioxolan-2-yl group) as starting material, as well as to the intermediate of the process.