baber/WOPTO huggingface dataset:
Patent CN-100571635-C (CN)
Title: 图像重构、投影数据评价方法及计算x线体层照相装置
Inventor: XIONGWEI YAN
IPC: A61B6/03
Filed: 2003-09-29
Granted: 2009-12-23
Abstract: 实现即使在完全没有相对数据的情况下也可根据部分扫描的投影数据来重构质量好的图像的方法、和可进行这种图像重构的X射线CT装置。在收集部分扫描的实测投影数据的图像信道空间中，对不存在实测投影数据的数据点A，用其镜点A’的实测投影数据来补充，形成完全扫描的投影数据，根据完全扫描的投影数据来重构图像，当镜点A’中没有实测投影数据时，利用通过其附近多个数据点B、C中的实测投影数据进行内插的数据。
Patent CN-100542558-C (CN)
Inventor: XUJIN ZHU
IPC: A61K35/64
Filed: 2007-05-01
Granted: 2009-09-23
Abstract: 本发明公开了一种治疗鼻炎的中药胶囊，它是将过300目筛子的炙僵蚕粉5份、炙蜂房粉3份，炙骨碎补粉10份、炙升麻粉6份，牡丹皮粉15份，白花蛇舌草粉15份经混合均匀、杀菌处理24小时、机器罐装而成的胶囊，上述份数均为重量份数。本发明将上述诸药配伍，炙僵蚕、炙蜂房共为君药，具有清热解毒，散瘀消肿，通窍祛风，臣以炙骨碎补、炙升麻升举清阳，增强肌体抵抗机能，消除鼻黏膜痈肿，佐以牡丹皮、白花蛇舌草抗病毒抵御风寒外邪，共奏通窍散瘀，解毒活血之功。因此，本发明的中药根据中医理论辨正施治，对过敏性鼻炎和鼻窦炎等各种顽固性鼻炎疗效显著，优于其他药方。
Patent CN-100583590-C (CN)
Title: 输电线路集成故障定位保护系统
Inventor: BAOHUI ZHANG
IPC: H02J13/00
Filed: 2007-08-03
Granted: 2010-01-20
Abstract: 本发明公开了一种输电线路集成故障定位保护系统，它主要包括接口通信单元、通信光纤网络、中央继电保护单元和多个断路器，接口通信单元包括多个测量和执行单元以及连接这些单元的通信光纤网络部分，测量和执行单元包括电流互感器、接口单元、通信以太网及网络开关，电流互感器和被保护输电线相连，接口单元的输入端与电流互感器的三相电流输出端相连，接口单元的输出端与断路器相连，接口单元的通讯端通过网络开关与该通信光纤网络相连，多个继电器通过网络开关与该通信光纤网络相连。该系统能够应用于高压输电线的保护，该系统与输电网的具体结构无关，不需要通信通道，构成简单，易于实现，且不敏感于故障类型，过渡电阻，故障初始角和电源配置，是一种高速且精确的故障定位保护方案。
Patent CN-100494607-C (CN)
Inventor: XIAOMING CHEN
IPC: E04H6/22
Filed: 2007-03-01
Granted: 2009-06-03
Abstract: 采用移动定位式作动器的车辆分隔定位横移取送装置属于交通工程机械式停车设备领域。本发明包括：横移底架、横移导向机构、横移驱动传动机构、定位驱动传动机构、移动定位式作动器、移动定位导向机构；横移底架设置在停车设备的前后车轮托放滚道之间横跨存车区内数个车位，通过横移驱动传动机构驱动、沿横移导向机构的导轨可左右双向横移一个车位的距离，横移底架上对应每一车位设有移动定位式作动器，其通过定位驱动传动机构驱动由移动定位导向机构约束反向移动伸张开定位或收拢，张开后止挡于车辆各车轮的内侧轮圈，张开后随同横移底架移动中推拉车辆。本发明结构简单、工作可靠，作为并排多车位滚道存放停车设备中车辆存取的横移输送装置。
Patent CN-100555285-C (CN)
Inventor: ZHEN ZHANG
IPC: G06F17/30
Filed: 2007-02-02
Granted: 2009-10-28
Abstract: 本发明涉及一种网页信息协同浏览系统，包括，一种网页信息协同浏览系统，包括，多个协同客户终端、连接各协同客户终端的服务器、协同代理模块。所述协同代理模块，用于根据来自任一协同客户终端的网页浏览指令，保存指令所请求的网页信息，并将所述网页信息通过服务器发送至所述协同客户终端之外的协同客户终端。本发明还涉及一种基于上述网页信息协同浏览系统的网页信息的协同浏览方法，本发明可以使得在网页限制访问的情况下，也可以实现网页信息协同浏览。
Patent CN-100532861-C (CN)
Inventor: GUOZHONG ZHAO
IPC: F04D29/42
Filed: 2007-09-30
Granted: 2009-08-26
Abstract: 本发明是涉及一种带便拆式机械密封结构的泵进出水段，主要包括进出水段，所述进出水段的吸入室和压出室由内外二个同心圆构成，内圆腔体作为吸入室，外圆腔体作为压出室，其中吸入室通过封闭的流道与进口管相连通，而压出室则直接与出口管连接；泵轴的一端从吸入室穿过与电机轴相连接，另一端与叶轮连接；泵轴与吸入室的连接处设有密封装置。本发明有益的效果是：从根本上解决了背景技术中存在的机械密封位于高压区内、需承受叶轮所产生的全部压力的问题。从而降低了对密封承受高压的结构要求，提高密封的可靠性和使用寿命。
Patent CN-100594780-C (CN)
Inventor: XINQIAO HE
IPC: A01K61/00
Filed: 2007-08-09
Granted: 2010-03-24
Abstract: 一种涉及养殖的小珍珠养殖方法，采用如下步骤：A、将创口面朝内包覆的细胞小片插入河蚌的外套膜内，B、将插片后的河蚌放回养殖水域中养殖，C、河蚌育珠成熟后，从外套膜内获取珍珠；步骤A包括如下步骤：A1、由河蚌的边缘膜割取切片，A2、保留切片中与河蚌的壳内壁相贴合的边缘膜膜片，A3、将所保留的膜片进一步分割，得若干块细胞小片，A4、将每块细胞小片的创口面向内折叠，A5、折叠后的细胞小片插入河蚌的外套膜内；步骤A中，每个河蚌的外套膜内插入多块细胞小片，各个细胞小片分布于外套膜内；细胞小片的数量为40-45，本发明提供了一种分泌珠养殖手段，能够实现分泌珠的规模化生产，经济价值高。
Patent CN-100565875-C (CN)
Title: 对称电感元件
Inventor: SHENGYUAN LI
IPC: H01F17/00
Filed: 2007-10-26
Granted: 2009-12-02
Abstract: 本发明揭示一种对称电感元件，配置于一基底上，包括：相互对称设置于一绝缘层上的第一及第二绕线部。每一绕线部包括由外而内同心排列的第一及第二半圈型导线层，且每一半圈型导线层具有一第一端及一第二端。一上跨接层及一下跨接层交错连接第一及第二半圈型导线层的第二端。连接上跨接层两端的半圈型导线层下方的绝缘层内分别具有第一及一第二内连线结构，其中每一内连线结构包括至少一导电层及电连接导电层及对应的半圈型导线层的多个导电插塞。
Patent CN-100543371-C (CN)
Inventor: YUZHEN LIN
IPC: F23R3/58
Filed: 2008-04-25
Granted: 2009-09-23
Abstract: 一种径向旋流器拐弯区液雾喷射预混预蒸发低污染燃烧室，燃烧室为单环腔结构，由燃烧室头部和火焰筒组成，其中燃烧室头部包括位于中心的预燃级和外圈的主燃级；采用主燃级燃油在主燃级径向旋流器后拐弯区内的液雾喷射方案，主燃级燃油在喷入拐弯区之前与空气预先混合，混合后再喷入到拐弯区中的油气混合物在主燃级径向旋流器旋流气体的作用下形成预混预蒸发油气混合物进入到燃烧区中燃烧，该燃烧方式能有效的降低燃烧室污染物的排放；同时主燃级燃油在主燃级径向旋流器后拐弯区内的液雾喷射以及拐弯区的拐弯流动可以减小燃烧室的长度；本发明主要用于航空发动机燃烧室，亦可用于工业燃气轮机和舰船燃气轮机燃烧室中，以减少排向大气中的污染物。
Patent PT-1204699-E (PT)
Inventor: CADE DOMINIQUE
IPC: C08L5/00
Filed: 2000-07-18
Abstract: The invention concerns compositions based on pullulan and a setting system for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard capsules. The composition preferably further contains a surfactant. By using aqueous solution of the inventive compositions, the hard pullulan capsules are produced by a conventional dipping moulding process under the same process condition range than conventional gelatine capsules.
Patent PT-1162383-E (PT)
Title: Compact braking assembly in an axle for an industrial vehicle
Inventor: PANIZZOLO FABRIZIO
IPC: F16H48/06
Filed: 2001-06-06
Abstract: A compact braking assembly in an axle for an industrial vehicle comprising, within an internal body (10) which extends in an arm (18), supported in a rotatable manner (in 16, 17) a casing (14) of a differential (15) provided with a first set of disks (20, 21), with a second set of disks (46, 47) also positioned between the casing (14) and said arm (18) of the axle, with a piston (41) acting on the first set of disks (20, 21), operated by a fluid fed from a respective duct (43), which axially moves a ring (44), distributor of an operating force of the piston (41), in which the piston (41) successively positions the first set of disks (20, 21) in a pack acting as a differential lock, subsequently positioning the second set of disks (46, 47) in a pack acting as a service brake thanks to the presence of a pre-established preloaded elastic element (24). <IMAGE>
Patent PT-1399373-E (PT)
Title: Preservative gas generating device
Inventor: SANDERSON RONALD DOUGLAS
IPC: B65D81/20
Filed: 2002-06-06
Abstract: A preservative gas generating device includes a carrier sheet and a layer of a matrix forming material having a preservative gas generating compound dispersed therein. The layer of matrix forming material permits the generation of a preservative gas by the preservative gas generating compound and to permit the gas to permeate out of the matrix formed by the material. The matrix forming material adheres to the carrier sheet in the form of a layer covering an area of the carrier sheet and forms at least one discrete zone, with a peripheral area of the carrier sheet surrounding the discrete zone(s) being substantially free of the matrix forming material. A cover sheet is secured to said peripheral area to enclose the layer of matrix forming material between the carrier sheet and the cover sheet. At least one of the carrier sheet and the cover sheet are permeable to said preservative gas.
Patent PT-1401754-E (PT)
Inventor: MUFF JOSEF
IPC: B66B13/30
Filed: 2002-06-25
Abstract: An elevator shaft door having a door panel composed of a front wall and rear wall, which walls are connected together by a thermally releasable material, wherein at least a part of the closing edge of the respective door panels consists of a profile member that is formed by the back wall or thermally non-detachably fastened to the back wall. In the case of a fire, the back wall separates from the front wall through release of the thermally releasable material, wherein the front wall curves by heat effect while the back wall with the closing edge retains the original shape.
Patent PT-1385515-E (PT)
Title: Spiropyrazole compounds
Inventor: GOEHRING R RICHARD
IPC: C07D471/10
Filed: 2002-04-18
Abstract: A compound of the formula (I):whereinZ, W, A, B, C, R1, R2, Q and n are as disclosed herein.
Patent PT-1406480-E (PT)
Title: Individual plant watering device
IPC: A01G29/00
Filed: 2002-07-01
Abstract: A fitting consisting of a part made of injected plastic for connecting a water tank and a hollow cone made of porous ceramics, so as to produce a device for dispensing water individually to plants, in particular potted plants, proximate to their roots, and in predetermined amount, comprising three coaxial parts; a disc-shape intermediate part with a central hole; a part consisting of one or two cylinders, arranged on one side of the disc and designed to be permanently fixed to the cone; a part consisting of one or two cylinders bearing a thread on the inner surfaces, arranged on the other side of the disc and capable of receiving a bottle removably screwed.
Patent PT-1545970-E (PT)
Title: Water jet drive for marine vehicles
Inventor: BECKER KARL-JOSEF
IPC: B63H11/04
Filed: 2002-10-04
Abstract: A compact operational retro-fit drive plant, for installation in the base of the bow or stern of various types of marine vehicle, in particular of displacement types, which serves for maneuvering and traveling at cruising speed on normal and particularly flat stretches of water. The drive plant includes a simple and economically produced water jet drive ( 1 ), having a propeller pump ( 8 ), for various types of engine and installations, which generates an efficient and completely controllable propeller thrust with optimized propeller approach flow and flat water capability. The propeller shaft ( 11 ) of the water jet drive ( 1 ) is arranged on the pressure side of the propeller pump ( 8 ) in a conventional 90 DEG elbow tube ( 6 ), the rotational axis ( 9 ) of the propeller is neither vertical nor horizontal, but has an inclination angle alpha of 20 DEG to 50 DEG, preferably between 25 DEG and 40 DEG relative to the baseplate ( 20 ) as a horizontal base. At the other end ( 14 ) of the elbow tube ( 6 ), which points downwards at an angle, an outlet housing section ( 7 ) is connected thereto and provided with a rotating base deflector array ( 16 ), in order to have control in all directions over the exit jet and thus the propeller thrust under the base of the water jet drive ( 1 ).
Patent PT-1525164-E (PT)
Title: Method and installation for the production of lime water from deionised water
Inventor: CLAUSSE FRANCK
IPC: C02F1/54
Filed: 2003-07-23
Abstract: A method of producing lime water comprising deionising dilution water by membrane filtration, distillation or an ion exchange resin and adding silicate ions to the deionised water. Thereafter, the deionised water treated with the silicate ions is mixed with milk of lime to form lime water. In one embodiment, the milk of lime and dilution water are mixed in a saturator where the silicate ions are introduced.
Patent PT-1479524-E (PT)
Title: Method and device for the production of a component with a pre-determined surface appearance
Inventor: BAUER JOERG
IPC: B44F9/02
Filed: 2004-05-21
Abstract: Method of manufacture of a part with surfaces that have a defined appearance, especially a wood grain appearance, has the following steps: production of a part with dimensions matching those of the finished product and production of a wood grain pattern on the part surface using an inkjet printer that is controlled so that the wood grain pattern on adjoining surfaces (90-96) matches at the edges formed between the two surfaces. The invention also relates to a corresponding device.
Patent PT-1605937-E (PT)
Title: Treatment of proliferative diseases with epothilone derivatives and radiation
Inventor: PRUSCHY MARTIN
IPC: A61K41/00
Filed: 2004-03-12
Abstract: This invention relates to organic compounds of formula (I) in particular to pharmaceutical compositions for use in combination with ionizing radiation for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.
Patent PT-1670574-E (PT)
Title: Method and apparatus for mixing of two fluids
Inventor: ABRAHAMSEN ROGER
IPC: B01F33/40
Filed: 2004-09-24
Abstract: A method and an apparatus for mixing of two fluids. The fluid is caused to flow into a mixing chamber (1). The gas is preferably mixed with the fluid before flowing into the mixing chamber. The chamber is vertically oriented and has a mainly cylindrical shape with smooth interior walls. The fluid is led into the chamber via a nozzle (7) in such a way that the fluid flows into the chamber at high velocity. During operation a turbulent gas/liquid phase is formed in the upper part of the chamber and mainly a fluid phase is formed in the lower part of the chamber. The fluid phase with mixed-in gas is drawn off from an outlet (8) arranged at the bottom of the chamber. The mixer could be connected to a transport pipe for fluid.
Patent PT-1700293-E (PT)
Title: Predictive coding scheme
Inventor: SCHULLER GERALD
IPC: G10L19/04
Filed: 2004-12-20
Abstract: The predictive coding method has successive information values of an information signal coded via an adaptive prediction algorithm which has initially selected prediction parameters and which is controlled via an adaption rate parameter, such that when the latter has a first value it operates with a first adaption rate and first prediction accuracy and when the adaption rate parameter has a second value it operates with the lower adaption rate and a higher adaption accuracy. The coding method provides switching between a higher adaption rate and a lower prediction accuracy and a lower adaption rate and a higher prediction accuracy for coding different parts of an information signal. Also included are Independent claims for the following: (A) a predictive coding device; (B) a decoding method for a predictive coded information signal; (C) a decoding device for a predictive coded information signal; (D) a computer program for a predictive coding method or a method for decoding a predictive coded information signal.
Patent PT-1650042-E (PT)
Title: Method of alignment of magnetic particles in a paste-like ink, and the printing of optical effects
Inventor: MAYER THOMAS
IPC: B41M3/14
Filed: 2005-10-19
Abstract: A method and apparatus is provided for printing using paste like inks such as those used in intaglio printing, wherein the inks include specialty flakes such as thin film optically variable flakes, or diffractive flakes. The invention discloses an apparatus having an energy source (13) such as a heat source for temporarily lessening the viscosity of the ink during alignment of the flakes within the ink by applying a magnetic or electric filed (7).
Patent PT-1588675-E (PT)
Title: Resorbable barrier micro-membranes for attenuation of scar tissue during healing
Inventor: HOLMES RALPH E
IPC: A61F2/00
Filed: 2001-03-12
Abstract: A system, comprising a resorbable scar-tissue reduction micro-membrane for attenuating a formation of post-surgical scar tissue between a healing post-surgical site and adjacent surrounding tissue following an in vivo surgical procedure on the post-surgical site, the resorbable scar-tissue reduction micro-membrane having a pre-implant configuration that is defined as a configuration of the implant immediately before the implant is formed between the post-surgical site and the adjacent surrounding tissue, the resorbable scar-tissue reduction micro-membrane having a first substantially-smooth side and a second substantially-smooth side, the resorbable scar-tissue reduction micro-membrane comprising a layer of resorbable polymer base material between the first substantially-smooth side and the second substantially-smooth side, the layer of resorbable polymer base material having a substantially uniform composition, a thickness of the layer of resorbable polymer base material, measured between the first substantially-smooth side and the second substantially-smooth side, being between 10 microns and 300 microns; and a bridging membrane, which comprises a thickness between 500 microns and 2000 microns and which is permeable.
Patent PT-1773300-E (PT)
Title: Solid pharmaceutical composition comprising mirtazapine
Inventor: RAJER TADEJA
IPC: A61K9/20
Filed: 2005-07-12
Abstract: The present invention relates to solid pharmaceutical compositions comprising mirtazapine and a cellulose derivative and in particular to granules and orally-disintegrating tablets.
Patent PT-1717493-E (PT)
Title: Helical compression spring for oil scraping piston ring
Inventor: BRILLERT HANS-RAINER
IPC: F16J9/06
Filed: 2006-04-24
Abstract: The spring (3) is comprised of a wire that is spirally wound and cleaned. An amorphous, wear-resistant graphite layer is at least partially formed on the spring through physical vapor deposition (PVD). The outer surface of the spring is chemically deburred so as to be bright and oxide-free.
Patent PT-2052984-E (PT)
Title: Method for preparing and forming a lid and lid
Inventor: DUCROT GUY
IPC: B21D51/38
Filed: 2007-10-25
Abstract: The invention concerns a method for preparing and forming an easy gripable and flat lying retortable lid having a lid ring (2) extending radially outside in a curl shape adapted to be seamed to a body flange of a container body, and extending radially inside in a substantially flat flange, sealed with an edge ring (3b) of a central foil (3), covering an inner opening (8) of the lid ring, radially inside of the inner end of the flat flange (2b). The central foil having a tab (10) extending from a radially outer end radially inside, and lying substantially parallel and close to an upper surface of the central foil (3). The tab has two radially extending portions, an outer one (10a) and an inner one (10b). The inner portion (10b) rising axially upward, during a press or squeeze operation (F ax ;30,40) in an intermediate portion (10c) between the inner and outer portions, to force the inner portion (10b) away from the foil surface and keep the outer portion substantially parallel to the foil. The lid is concerned as well. The lid comprises a lid ring (Deckelring) and a lid foil (membrane), which work together and are coupled together by a sealing portion which seals in ring-like fashion the membrane to a panel of the lid ring.
Patent PT-2007507-E (PT)
Title: Knitted support for tubular membranes
Inventor: MOLENBERGHS BART
IPC: B01D69/08
Filed: 2007-04-10
Abstract: A method of manufacturing a reinforced tubular membrane comprises the steps of manufacturing the tubular support from monofilament thread, impregnating the support with membrane dope and adjusting the inner and the outer diameter of the membrane. A coating apparatus comprises a casting bob and an orifice to adjust respectively the inner and outer diameter of the membrane. A tubular reinforced polymeric membrane comprises a tubular support and membrane substance. The tubular support is made of monofilament thread and has a sufficiently open structure (openings larger than 0.1 mm). Touching and/or engaging parts of the thread may be linked prior to impregnating the support with membrane dope. The support may comprise loops of the monofilament thread, which are also linked.
Patent PT-2049193-E (PT)
Title: Coupling device
Inventor: ARDUINI ARDUINO
IPC: A61M1/28
Filed: 2007-08-13
Abstract: A coupling device (1) for the connection of two ends (3, 9) of respective tubular members (2, 5), allowing the contact of the flowing fluid only with elements inside a closed container, circumstances and an inherently easy connection operation, thus it can be carried out, comprising: a closed container (10) housing said ends (3, 9) of respective tubular members (2, 5), one of said tubular members having a flexible terminal section (8) thereof inside said closed container; a mobile connection member (15), coupled at the end of said flexible terminal section (8), having a nozzle (16) apt to be inserted within a receiving end of the other tubular member,-and a cam device, located inside said closed container (10) and apt to be actuated from the outside of said closed container, apt to cooperate with said mobile connection member (15), the cam device causing the insertion and the ejection of said nozzle in and from said receiving end, and the corresponding connection and the disconnection of the two ends.
Patent PT-2337791-E (PT)
Title: Utilization of fatty acid desaturases from hemiselmis spp
Inventor: URSIN VIRGINIA
IPC: A23L7/10
Filed: 2009-10-14
Abstract: The invention relates to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using exogenous desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the exogenous desaturase enzymes utilized are Hemiselmis spp. delta 5 desaturases. Also provided are improved soybean oil compositions having EPA derived from plants carrying the genes of interest.
Patent PT-2298494-E (PT)
Title: Tool holder with a suction system, an axial knuckle joint and a sensing device
Inventor: HERMOSO JULIAN BAIGORRI
IPC: B23Q11/00
Filed: 2005-07-28
Abstract: This patent document relates, as its title indicates, to a tool holder with suction system of the type used in automatic machining systems with numerical control for the adaptation and securing of different machining tools,  characterised in that  an axial knuckle joint (45) in the sensing device (43) is incorporated into the tool holder, in both its fixed version and retractable versions, thereby enabling automatic adaptation to the irregularities of the surface (46) to be machined, with the subsequent reduction in machining error. The invention being presented herein presents the principal advantages of enabling machining that is more precise in depth than conventional systems, at the same time as all the waste generated by the machining is automatically evacuated by the suction system, all by means of a single device.
Patent PT-2263722-E (PT)
Title: Pen-type injector with dose dial sleeve
Inventor: PLUMPTRE DAVID AUBREY
IPC: A61M5/24
Filed: 2004-03-03
Abstract: The invention relates to a drive mechanism for use in a drug delivery device comprising: 
an internal housing having an external helical thread, which internal housing is provided within a main housing; 
a dose dial sleeve (70) having a helical thread engaged with the helical thread of the said internal housing; 
a drive sleeve (30) releasably connected to the said dose dial sleeve (70); 
and a clutch means (60) located between the dose dial sleeve (70) and the drive sleeve (30);  When the dose dial sleeve (70) and the drive sleeve (30) are coupled, both are allowed to rotate with respect to the internal housing.  When the dose dial sleeve (70) and the drive sleeve (30) are de-coupled, rotation of the dose dial sleeve (70) with respect to the internal housing is allowed, whilst rotation of the drive sleeve (30) with respect to the internal housing is not allowed, whereby axial movement of the drive sleeve (30) is allowed so that a force is transferred in the longitudinal direction to the proximal end of the drug delivery device.
Patent PT-2266648-E (PT)
Title: Pen-type injector with dose dial sleeve
Inventor: PLUMPTRE DAVID AUBREY
IPC: A61M5/24
Filed: 2004-03-03
Abstract: The invention relates to a drive mechanism for use in a drug delivery device comprising: 
an internal housing having an external helical thread, which internal housing is provided within a main housing; 
a dose dial sleeve (70) having a helical thread engaged with the helical thread of the said internal housing; 
a drive sleeve (30) releasably connected to the said dose dial sleeve (70); 
and a clutch means (60) located between the dose dial sleeve (70) and the drive sleeve (30);  When the dose dial sleeve (70) and the drive sleeve (30) are coupled, both are allowed to rotate with respect to the internal housing.  When the dose dial sleeve (70) and the drive sleeve (30) are de-coupled, rotation of the dose dial sleeve (70) with respect to the internal housing is allowed, whilst rotation of the drive sleeve (30) with respect to the internal housing is not allowed, whereby axial movement of the drive sleeve (30) is allowed so that a force is transferred in the longitudinal direction to the proximal end of the drug delivery device.