baber/WOPTO huggingface dataset:
Patent CA-2497632-A1 (CA)
Title: Nouveaux derives de thiophene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
Inventor: DUBLANCHET ANNE-CLAUDE
IPC: C07D409/12
Filed: 2003-08-07
Abstract: Composés de formule (I) caractérisés en ce que .bullet. X représente oxygène ou soufre, .bullet. Y représente oxygène,-NH ou -N(C1-C6)alkyle, .bullet. Ra représente hydrogène, halogène, (C1-C3)alkyle, hydroxy, ou (C1-C3)alkoxy, .bullet. Rb représente hydrogène, halogène, ou (C1-C3)alkyle, .bullet. A représente phényle, pyridyle, (C5-C6)cycloalkyle ou (C5-C6)cycloalkènyle, .bullet. R1 et R2 représentent chacun un groupement choisi parmi hydrogène, halogène, cyano, nitro, halogénoalkyle, halogénoalkoxy, alkyle, alkènyle, alkynyle, -OR4, -NR4R5, -S(O)nR4, -C(O)R4, -C02R4, -O-C(O)R4, -C(O)NR4R5, -N R5- C(O)R4, -NR5-S02R4, -T-CN, -T-OR4, -T-OCF3, -T-NR4R5, -T-S(O)nR4, -T-C(O)R4, - T-C02R4, -T-O-C(O)R4, -T-C(O)NR4R5, -T-NR4-C(O)R5, -T-NR4-S02R5, -R6, et -T- R6 dans lesquels n, T, R4, R5 et R6 sont tels que définis dans la description, .bullet. R3 représente un groupement -R7 ou -U-R11, dans lesquels R7 représente hydrogène, alkyle, aryle, cycloalkyle ou hétérocycle, U représent e une chaîne alkylène linéaire ou ramifiée, et R11, est tel que défini dans la description, leurs isomères optiques ou leurs sels d'addition à un acide ou à une base pharmaceutiquement acceptable, et leur utilisation en tant qu'inhibiteur de métalloprotéinase et plus spécifiquement de la métalloprotéinase -12.
Patent CA-2497973-A1 (CA)
Title: Antibiotic microspheres for treatment of infections and osteomyelitis
Inventor: AMBROSE CATHERINE G
IPC: A61K38/14
Filed: 2003-09-05
Abstract: Biodegradable microspheres implanted, injected, or otherwise placed totally or partially within the body are capable of near-linear controlled release of a n antibiotic for a predetermined period of time for the treatment and preventi on of infections involving the body. The microspheres are formed of polylactic- co- glycolic acid (PLGA) and an effective amount of antibiotic sufficient to produce bactericidal levels in body tissues, and may or may not include polyethylene glycol (PEG). The microspheres exhibit near-linear delivery of the antibiotic for at least 4 weeks at levels exceeding the minimum inhibito ry concentration (MIC) for organisms commonly found to be the cause of infectio ns.
Patent CA-2499342-A1 (CA)
Title: Systeme et procede de configuration d'une unite de commande de moteur pourvue d'un dispositif externe
Inventor: MAYHEW SCOTT
IPC: H02P1/26
Filed: 2003-08-12
Abstract: L'invention concerne un système à unité de commande de moteur configurable à distance, comprenant une unité de commande de moteur et un dispositif de configuration à distance. L'unité de commande de moteur comprend des commutateurs à l'état solide assurant la connexion entre une ligne c.a. et les bornes du moteur pour régler l'alimentation c.a. du moteur, et un circuit de commande pour commander le fonctionnement des commutateurs à l'état solide. Le circuit de commande comprend un processeur programmé pour commander le fonctionnement des commutateurs à l'état solide, et une mémoire connectée au processeur programmé, stockant des informations de configuration concernant le fonctionnement des commutateurs à l'état solide. Une interface de communication sans fil est connectée au processeur programmé. Le dispositif de configuration à distance comprend une interface utilisateur à distance permettant de sélectionner des paramètres pour les informations de configuration stockées, et une interface de communication sans fil avec l'unité de commande du moteur, de manière que l'interface utilisateur puisse être utilisée pour configurer l'unité de commande du moteur par mise à jour des informations de configuration stockées à l'aide des paramètres sélectionnés.
Patent CA-2499880-A1 (CA)
Title: Methods and compositions for modification of splicing of pre-mrna
Inventor: KOLE RYSZARD
IPC: C12Q1/68
Filed: 2003-09-26
Abstract: The present invention provides a method of preventing a splicing event in a pre-mRNA molecule, comprising contacting the pre-mRNA and/or elements of the splicing machinery with a small molecule compound identified according to the methods described herein to prevent the splicing event in the pre-mRNA  molecule. Further provided is a method of inducing a splicing event in a pre-mRNA molecule, comprising contacting the pre-mRNA and/or elements of the splicing machinery with a small molecule compound identified according to the methods described herein to induce the splicing event in the pre-mRNA  molecule. Furthermore, a method is provided herein of treating a patient having a disorder associated with an alternative or aberrant splicing event in a pre-mRNA molecule, comprising administering to the patient a therapeutically effective amount of a compound identified according to the methods described herein to prevent an alternative or aberrant splicing event in a pre-mRNA  molecule, thereby treating the patient.
Patent CA-2501208-A1 (CA)
Title: Decomposition and modification of silicate and silicone by silase and use of the reversible enzyme
Inventor: KRASKO ANATOLI
IPC: C12N15/60
Filed: 2003-10-02
Abstract: Silicase is an enzyme which can cause amorphous and crystalline silicon dioxide to dissolve, forming free silicic acid. The invention relates to the use of recombinant silicase or silicase isolated from natural sources, and t o the use of silicase fusion proteins and carboanhydrase in addition to carboanhydrase-related enzymes for the decomposition, modification and synthesis (reversible silicase reaction) of silicon dioxide (condensation products of silicic acid, silicates), silicons and other silicon (IV) compounds or metal (IV) compounds and the technical use thereof.
Patent CA-2502030-A1 (CA)
Title: Method for forming compact from powder and mold apparatus for powder molding
Inventor: KAWASE KINYA
IPC: B22F3/035
Filed: 2003-11-18
Abstract: A method for forming a compact from a powder wherein a forming portion 1A  in a mold body 2 is filled with a raw powder and upper and lower punches 3,4 are fitted into the forming portion 1A to form the compact. Prior to filling the forming portion 1A  with the raw powder M, a solution L with a lubricant being uniformly dissolved in a solvent is applied to a peripheral portion of the forming portion 1A, and then the solution is evaporated, thus forming a crystallized layer B thereon. Thus, the reduction of a force for ejecting the compact is realized, while improving the density of the compact, realizing the stable and successive production of the compact
Patent CA-2502901-A1 (CA)
Title: Protective footwear
Inventor: DION DENIS
IPC: A43B13/42
Filed: 2005-03-31
Abstract: A protective footwear incorporating a special ballistic grade pliable protector designed to protect the vulnerable arch area of the foot from mufti-directional punctures. As an integral part of the boot, the protector provides protection from different sharp objects having multiple angles of incident. The protector is made of multiple layers of woven ballistic fabric and is adapted to trap the sharp point of the protruding object in its fabric webbing preventing it from being redirected to a more vulnerable and exposed area of the foot.
Patent CA-2504289-A1 (CA)
Title: Method and apparatus for dynamic group address creation
Inventor: ALLEN ANDREW MICHAEL
IPC: H04M11/04
Filed: 2005-04-14
Abstract: Method and apparatus for creating and maintaining dynamic group addresses for facilitating Push-to-Talk over Cellular (PoC) group communication sessions among mobile stations in a communications network are disclosed. In one embodiment the method comprises receiving at least one rule defining a member of the dynamic group in association with a group address; and populating the dynamic group with members from said mobile stations determined in accordance with the at least one rule. Rules may be defined with reference to presence and/or location information available for the mobile stations. Such information may be published on behalf of the stations to one or more servers adapted to identify mobile stations matching the rules. The method may comprise subscribing to the servers to obtain the matching mobile stations with which to populate dynamic group addresses.
Patent CA-2505690-A1 (CA)
Inventor: PRICE RAYMOND R
IPC: B28B7/00
Filed: 2001-11-14
Abstract: A block texturing apparatus (10) and method for forming a block with a textured surface. The block texturing apparatus (10) has a body (20) with a front surface (22), a rear surface (24), a top surface (26), a bottom surface (30), and opposing side surfaces (36, 38). The front surface (22) has a block modifying section (40) that occupies at least twenty percent of the front surface (22) of the body (20). In operation, the block texturing apparatus (10) is used in conjunction with or in lieu of a wall of a mold (70). The mold (70) is than filled with a mixture of block material (90) that is compressed in the mold (70) to form a block (94). The block (94) is then stripped from the mold (70). As the block (94) is removed, the block modifying section (40) manipulates a surface of a block (94) and imparts an irregular texture (96) thereto.
Patent CA-2506278-A1 (CA)
Title: A foamer/sulfur scavenger composition and methods for making and using same
Inventor: TURK STEVE
IPC: C09K23/00
Filed: 2005-05-04
Abstract: A new multi-purpose foaming composition having applications in oil field application, industrial applications, waste management applications, or other applications that can be benefitted by a foam, is disclosed, where the composition includes a surfactant, a sulfur scavenger and optionally an additive, where the sulfur scavenger and/or additive improve foam characteristics and/or the foam improves an activity of the sulfur scavenger and/or the additives. Method for using and making the foaming compositions are also disclosed, especially, coiled and capillary coiled tubing downhole applications.
Patent CA-2507753-A1 (CA)
Title: Use of creatine or creatine analogs for the treatment of diseases of the nervous system
Inventor: DAOUK GHALEB
IPC: A61K31/675
Filed: 1995-11-07
Abstract: The present invention relates to the use of creative compounds including creatine, creatine phosphate or analogs of creatine, such as cyclocreatine, for treating diseases of the nervous system. Creative compounds can be used as therapeutically effective agents against a variety of diseases of the nervous system such as diabetic and tonic neuropathies, peripheral nervous system diseases, Alzheimer disease, Parkinson's disease stroke, Huntington's disease, motor neuron disease, traumatic nerve injury, multiple sclerosis, dysmyelination and demyelination disorders and mitochondrial diseases. The Creatine compounds which can be used in the present method include: (1) creatine, creatine phosphate and analogs of these compounds which can act as substrates or substrate analogs for creatine kinase; (2) bisubstrate inhibitors of creatine kinase comprising covalently linked structural analogs of adenosine triphosphate (ATP) and creative; (3) creative analogs which can act as reversible or irreversible inhibitors of creatine kinase; and (4) N-phosphorocreatine analogs bearing non-transferable moieties which mimic the N-phosphoryl group.
Patent CA-2514209-A1 (CA)
Title: Modine manufacturing company
Inventor: REINKE MICHAEL J
IPC: F28D9/00
Filed: 2003-12-18
Abstract: An evaporative heat exchanger (10) is provided for the transfer of heat to a first fluid (30) from a second fluid (28) and a third fluid (22) to vaporize the first fluid (30). The heat exchanger (10) includes a core (40), a first flow path (60) in the core for the first fluid (30), a second flow path (66) in the core (40) for the second fluid (28), and a third flow path (68) in the core (40) for the third fluid (22). The core (40) includes a first section (42), a second section (44), and a third section (46), with the second section (44) connecting the first and third sections (42, 46). The first flow path(60) extends through all of the sections (42, 44, 46), the second flow path (66) extends through the first section (42); and the third flow path (68) extends through the third section (46).
Patent CA-2515468-A1 (CA)
Title: Pressure shell, high-pressure tank provided with the pressure shell, manufacturing method of the high-pressure tank and manufacturing apparatus of the high-pressure tank
Inventor: OHTA TOSHIAKI
IPC: B29C53/60
Filed: 2004-02-03
Abstract: A pressure shell formed by winding reinforcement fibers with resin material for hardening on the outer surface of a hollow tank base body, a high-pressure tank having the pressure shell, a method of manufacturing the high-pressure tank, and an apparatus for manufacturing the high-pressure tank, the pressure shell formed in a laminated structure in which a large number of fiber layers formed by winding the reinforcement fibers on the tank base body are laminated wherein with the inside of the high-pressure tank emptied, a compressive stress is applied to the lower fiber layer and a tensile stress is applied to the upper fiber layer. When the reinforcement fibers are wound on the tank base body, fluid for pressure regulation is filled in the tank base body and the reinforcement fibers are wound while regulating a pressure applied to the fluid for pressure regulation and adjusting a tension applied to the reinforcement fibers.
Patent CA-2516705-A1 (CA)
Title: Aminocyclopentyl fused heterotricylicamide modulators of chemokine receptor activity
Inventor: GOBLE STEPHEN D
IPC: C07D471/02
Filed: 2004-02-23
Abstract: The present invention is directed to compounds of formulae (I and II) (wherein A, D, E. X, l, m, n and R1 through R18 are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
Patent CA-2516732-A1 (CA)
Title: Wireless network architecture
Inventor: HAWE WILLIAM R
IPC: H04M3/00
Filed: 2004-02-18
Abstract: The performance and ease of management of wireless communications environments is improved by a mechanism that enables access points (APs) to perform automatic channel selection. A wireless network can therefore include multiple APs, each of which will automatically choose a channel such that channel usage is optimized. Furthermore, APs can perform automatic power adjustment so that multiple APs can operate on the same channel while minimizing interference with each other. Wireless stations are load balanced across AN so that user bandwidth is optimized. A movement detection scheme provides seamless roaming of stations between APs.
Patent CA-2519636-A1 (CA)
Title: Methods and apparatus for treatment of patent foramen ovale
Inventor: MALECKI WILLIAM
IPC: A61M25/10
Filed: 2004-03-26
Abstract: Methods and apparatus for treatment of patent foramen ovale (PFO) generally include the use of a catheter (10) having a treatment device including one or more abrasive needles (12) at the distal end. In other embodiments, an energy transmission member or one or more apertures for dispensing a fluid may be used to contact and close the PFO.
Patent CA-2522838-A1 (CA)
Inventor: GRIMSHAW SCOTT
IPC: G01N29/12
Filed: 2004-04-19
Abstract: A device for measuring thickness and/or rate of thickness increase of a film comprises at least one piezoelectric element, and first and second electrodes in contact with the piezoelectric element. A method of measuring thickness and/or rate of thickness increase of a film comprises applying a voltage across a piezoelectric element from a first electrode to a second electrode, thereby causing the piezoelectric element to vibrate, and measuring the rate of vibration of the piezoelectric element. Heat may be applied to the piezoelectric element. The piezoelectric element may be formed of quartz crystal, e.g., IT-cut.
Patent CA-2524519-A1 (CA)
Title: Compounds as crf1 receptor antagonists
Inventor: FU JIAN-MIN
IPC: A61P25/00
Filed: 2004-05-05
Abstract: The present invention relates to compounds of Formula I,or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compounds of the inventions are CRF, receptor antagonists. Compounds of the invention are useful for treating, in a warm-blooded animal, particularly a mammal, and more particularly a human, various disorders that are associated with CRF or CRF, receptors, or disorders the treatment of which can be effected or facilitated by antagonizing CRF, receptors.
Patent CA-2528204-A1 (CA)
Inventor: REEVES CARY R
IPC: A61B17/70
Filed: 2004-06-04
Abstract: The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises a plurality of pieces of bone and a flexible mechanism including one or more flexible, elongate, biocompatible connectors interconnecting the pieces of bone.
Patent CA-2528416-A1 (CA)
Inventor: THEORET RICHARD
IPC: A01G9/24
Filed: 2005-11-29
Abstract: ABSTRACT  A hydro-thermo irrigation mat is comprised of a base sheet, a water-permeable root-shielding top sheet, and a capillary mat of absorbent material therebetween. One or more flat pliable drip tapes are loosely disposed in spaced-apart relationship between the top sheet and the capillary mat. Hot water convection tubes are disposed co-axially with the drip tapes but between the base sheet and the capillary mat. The drip tapes are connected to a water supply line and the hot water convection tubes are secured to a hot water supply line. Water within the mat is heated and distributes heat from the hot water convection tubes substantially throughout the mat.
Patent CA-2532436-A1 (CA)
Title: System and methods of deriving fluid properties of downhole fluids and uncertainty thereof
Inventor: MULLINS OLIVER C
IPC: E21B49/10
Filed: 2006-01-10
Abstract: Methods and systems are provided for downhole analysis of formation fluids by deriving fluid properties and associated uncertainty in the predicted fluid properties based on downhole data, and generating answer products of interest based on differences in the fluid properties. Measured data are used to compute levels of contamination in downhole fluids using an oil-base mud contamination monitoring (OCM) algorithm. Fluid properties are predicted for the fluids and uncertainties in predicted fluid properties are derived. A statistical framework is provided for comparing the fluids to generate, in real-time, robust answer products relating to the formation fluids and reservoirs thereof. Systematic errors in measured data are reduced or eliminated by preferred sampling procedures.
Patent CA-2532949-A1 (CA)
Inventor: TREADO PATRICK J
IPC: G01J3/30
Filed: 2004-07-19
Abstract: L'invention concerne un procédé et un appareil pour spectromètre d'imagerie multilongueurs d'ondes. Dans un mode de réalisation, l'invention concerne plus particulièrement un filtre optique laissant passer les photons. Ce filtre comprend un premier et un deuxième étages de filtre. Le premier étage de filtre peut comprendre un premier élément retardateur et une première cellule à cristaux liquides. Le premier élément peut comprendre une face d'entrée et une face de sortie, une desdites faces n'étant pas orientée sensiblement perpendiculaire à la trajectoire des photons traversant le filtre.
Patent CA-2533336-A1 (CA)
Inventor: VOGEL MICHAEL
IPC: A61M5/315
Filed: 2004-07-23
Abstract: A safety clip (100) for a medical catheter features a slider (6) for stepless adjustment of a distance separating an abutment surface for a sleeve (20) of the catheter from an abutment surface for a shaft (22) of the catheter.
Patent CA-2533516-A1 (CA)
Inventor: BRISKEY WILLIAM J
IPC: B27C1/00
Filed: 2004-07-23
Abstract: L'invention concerne une technique unique d'identification et de caractérisation "woodprint<SP>TM</SP>", faisant appel à des caméras (16), à un éclairage (14), à un matériel d'interface de caméra (18), à un ordinateur (20), et/ou à un logiciel de traitement d'image, pour recueillir et pour analyser des caractéristiques de surface de morceaux de bois (8), pour les tracer lors de leur procédé de production automatisé, en temps réel, et avec des informations spécifiques à chaque morceau de bois (8), notamment, le type d'usinage voulu, la valeur du bois, et/ou sa destination. Lorsqu'un morceau de bois (8) atteint un point du procédé de production où une décision est nécessaire, son identité unique est utilisée pour extraire des informations appropriées préalablement prédéterminées et attribuées à ce morceau de bois (8).
Patent CA-2537022-A1 (CA)
Title: Purification catalyst for exhaust gas, production method therefor, and purification catalyst device for exhaust gas
Inventor: KIGUCHI KAZUNORI
IPC: B01D53/94
Filed: 2004-08-20
Abstract: An exhaust gas clarifying catalyst which has an Al oxide and, carried thereon, a Pd oxide, characterized in that the Al oxide is LnAlO3 [wherein Ln represents a rare earth element]. The exhaust gas clarifying catalyst has a noble metal itself exhibiting enhanced activity as compared to the metal contained in a conventional catalyst, and also can prevent its catalytic activity from being lowered by the exposure to a high temperature, which results in the exhibition of satisfactory catalyst performance also in the operation at the start-up and in a low temperature operation (at 400~C or lower).
Patent CA-2537937-A1 (CA)
Title: System and method for setting up a universal remote control
Inventor: HAYES PATRICK H
IPC: H04Q5/22
Filed: 2004-08-23
Abstract: A system and method for using an RFID tag to automatically setup and configure a universal remote control to command appliances of various types and various manufacturers.
Patent CA-2538713-A1 (CA)
Inventor: FUJIWARA TATSUYA
IPC: F23D14/78
Filed: 2006-03-07
Abstract: An object of the present invention is to provide a combustion apparatus equipped with a pilot burner and a main burner capable of establishing a stable combustion state without involving generation of CO and unburned substances at the main burner even when the supply of a gas fuel to the pilot burner is stopped.      A combustion apparatus equipped with a pilot burner and a main burner according to the present invention is characterized in that, when the main burner is in a combustion state, the amount of air supplied to the pilot burner can be adjusted. Here, the amount of air supplied to the pilot burner is an amount allowing the pilot burner to be cooled.
Patent CA-2539033-A1 (CA)
Inventor: LINDQUIST PER
IPC: A61K9/00
Filed: 2004-09-10
Abstract: Methods for modulating neurogenesis in vitro and in vivo have been disclosed.  The methods comprise contacting neural stem cells with an effective amount of a FTY720 compound. The neurogenesis may involve the modulation of proliferation, differentiation, migration or survival of a non-embryonic neural stem cells or progenitor cells. Also disclosed are methods for the prevention or treatment of neurological disorders including Parkinson~s desease, Parkinsonian disorders, Hutington~s disease, Alzheimer~s disease, amyotrophic lateral sclerosis, spinal ischemia, ischemic stroke, spinal cord injury, cancer-related brain injury, and cancer-related spinal cord injury, Shy-Drager syndrome, progressive supranuclear palsy, Lewy body disease, stroke, cerebral infarction, multi-infarct dementia, and geriatric dementia, comprising administering to a subject a therapeutically effective amount of a FTY720 compound.