baber/WOPTO huggingface dataset:
Patent NZ-242124-A (NZ)
Title: Dna encoding an enzyme having arabinan-degrading activity
Inventor: VAN HEUVEL MARGARETHA
IPC: A23K30/18
Filed: 1992-03-25
Abstract: The present invention provides the cloning and expression of purified and isolated DNA molecules, obtainable from fungi, which encode enzymes having arabinan-degrading activity. The present invention also provides DNA constructs containing these DNA molecules and methods for their enhanced expression in selected microbial host cells. The present invention further provides methods for the use of the thus-produced arabinan-degrading enzymes.
Patent NZ-245173-A (NZ)
Title: Disposable diaper with two side flaps per side
Inventor: VANDEMOORTELE PHILIPPE
IPC: A61F13/15
Filed: 1992-11-18
Abstract: A disposable absorbent article of hygiene includes an absorbent pad disposed between an outer support sheet and an inner cover sheet and has two elasticized side flaps fastened to the cover sheet along the lengthwise edges of the article. Each flap is fastened to the cover sheet over the length of the article by a proximal portion of the flap positioned on an inner side of the absorbent pad, and is folded along the lengthwise direction. The flap is also fastened to the cover sheet in the folded state at end regions of the article so that a distal edge of the flap overlaps the proximal edge over the length of the article, and remains unattached in a region between the end regions to form a pouch.
Patent NZ-247550-A (NZ)
Title: Pharmaceutical composition comprising mycelia of streptomyces avermitilis, strains and prepentive methods
Inventor: CAPPELLETTI LEONARDO M
IPC: C12N1/20
Filed: 1993-05-05
Abstract: By carrying out the fermentation of Streptomyces avermitilis ATCC 55278, a dried mycelium is obtained which, orally administered to animals, particularly to ovines, has an antiparasitic activity.
Patent NZ-248821-A (NZ)
Title: Quaternary aza (bi- or tri-)cyclic basic amides, preparation and medicaments thereof
Inventor: EDMONDS-ALT XAVIER
IPC: A61K31/14
Filed: 1993-09-30
Abstract: The invention relates to basic quaternary amides of formula <IMAGE>  in which   - Ar represents an optionally substituted mono-, di- or tricyclic heteroaromatic or aromatic group; - T represents a direct bond, a hydroxymethylene group, an alkoxymethylene group in which the alkoxy group is C1-C4 or a C1-C5 alkylene group; - Ar' represents a phenyl which is unsubstituted or substituted one or a number of times, a thienyl, a benzothienyl, a naphthyl or an indolyl; - R represents hydrogen, a C1-C4 alkyl, an  omega -(C1-C4)alkoxy(C2-C4)alkyl or an  omega -(C1-C4)alkanoyloxy(C2-C 4)alkyl,   - Q represents hydrogen; - or else Q and R, together, form a 1,2-ethylene, 1,3-propylene or 1,4-butylene group;   - Am<(+)> represents the radical <IMAGE> in which X1, X2 and X3, together and with the nitrogen atom to which they are bonded, form an azabicyclic or azatricyclic system optionally substituted by a phenyl group;   - A<(-)> is a pharmaceutically acceptable anion.   These compounds are useful in the preparation of medicaments intended for the treatment of pathologies involving the tachykinin system.
Patent NZ-248946-A (NZ)
Title: Piperidine derivatives
Inventor: VILLALOBOS ANABELLA
IPC: C07D/
Filed: 1992-03-27
Abstract: Compounds of formula (I) wherein R<1>, R<2>, R<7>, R<8>, X, Y, M and L are defined as below. The compounds of formula (I) are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.
Patent NZ-263631-A (NZ)
Title: Horseshoe: core of metal surrounded by a plastic or rubber material
Inventor: PEDERSEN LONE
IPC: A01L5/00
Filed: 1994-03-07
Abstract: PCT No. PCT/SE94/00193 Sec. 371 Date Jan. 22, 1996 Sec. 102(e) Date Jan. 22, 1996 PCT Filed Mar. 7, 1994 PCT Pub. No. WO94/22296 PCT Pub. Date Oct. 13, 1994A horseshoe includes a core of metal which is surrounded by a plastic or rubber material. The horseshoe is provided with a number of apertures (10) which are intended for nails and which taper upwardly from the underside (4) of the horseshoe. In order to facilitate the correct alignment of the nails when these are driven into a horseshoe of relatively great vertical thickness, the center points of the largest and smallest sections of the aperture (10) are offset in a horizontal plane relative to one another in a direction towards or away from a central region (3) of the horseshoe. This offset may vary in both size and direction from one aperture to the next within the same horseshoe.
Patent NZ-281889-A (NZ)
Title: Use of phosphorus derivatives of n-containing heterocyclics
Inventor: NOWICKY WASSYL
IPC: A61P3/02
Filed: 1995-03-20
Abstract: PCT No. PCT/AT95/00055 Sec. 371 Date Jul. 9, 1996 Sec. 102(e) Date Jul. 9, 1996 PCT Filed Mar. 20, 1995 PCT Pub. No. WO95/25522 PCT Pub. Date Sep. 28, 1995The invention concerns the use of phosphorus derivatives of alkaloids of the general formula (I), for preparing a medicament for treating endocrinopathies, in particular for treating osteoporosis.
Patent NZ-319879-A (NZ)
Title: Pressure-regulating ear plug
Inventor: MOBLEY J PHIL
IPC: A61F11/06
Filed: 1996-09-30
Abstract: A pressure regulating ear plug for regulating the rate of change of pressure inside an ear to minimize the pressure differential between the middle ear and a volume of the external ear cavity adjacent the ear drum is made of an ear plug adapted to fit tightly within the external ear cavity with no or minimal air leakage, and disposed within the ear plug is a pressure regulator with a slow leak rate. The pressure regulator is preferably made of a porous ceramic material.
Patent NZ-329471-A (NZ)
Title: Use of monoamide oxidase b inhibitors to treat parkinson's disease
Inventor: BREWER FRANCESCA MARY
IPC: A61K31/40
Filed: 1996-03-01
Abstract: A fast dispersing solid pharmaceutical composition having a monoamine oxidase B inhibitor as the only active ingredient is disclosed for the treatment of Parkinson's disease. The composition is formulated to promote absorption through the buccal, sublingual, pharyngeal and/or esophageal mucous membranes, such that at least 5% of the active ingredient is absorbed in one minute, as determined by a buccal absorption test.
Patent NZ-331447-A (NZ)
Title: Macrocyclic peptides useful in the treatment of thrombin related disorders
Inventor: GRECO MICHAEL N
IPC: C07K5/02
Filed: 1997-02-19
Abstract: The present invention relates to compounds that are inhibitors of serine proteases, particularly a-thrombin and may be used in a variety of thrombin related disorders such as venous thrombosis and arterial thrombosis. Thrombin acts as a procoagulant through activation of the protein C pathway (followed by inactivation of coagulation factors V and VIII). Compound shown in Formula (I) seems to be useful in the treatment of thrombin and trypsin related disorders. Wherein m is 2 to 12 A is shown as formula (II)  Wherein   R3 is H, OH or C1-5alkoxy,    n is 1 or 2;    a is 0 to 1; B is shown as formula (III) Wherein R4 is independently selected from common C1-5 substituents as described  R5 and R6 are H or taken together with the carbon of attachment to form a carbonyl, and  B is 0 or 1 G is shown as formula (IV)  Wherein R7 as described in R4 E is carbon or C(CH2)q-, where q is 0 to 12, with the proviso that the sum of q and m cannot exceed 25 R8 and R9 are hydrogen or taken together with the carbon E to form a carbonyl, and G is 0 to 1
Patent NZ-331657-A (NZ)
Title: Rheometer with blades tilted from the axial direction
Inventor: FREEMAN REGINALD EDWARD
IPC: G01N11/14
Filed: 1997-03-24
Abstract: A rheometer for assessing characteristics of materials includes a vessel (5, 25) and a rotor (6, 26) or the like disposed in use within the vessel. The vessel (5, 25) contains a material (7, 27), the characteristics of which are to be assessed. The rotor (6, 26) or the like is passed through the material to be assessed. The vessel (5, 25) and the rotor (6, 26) or the like are constructed and adapted so as to be simultaneously rotatable relative to each other about an axis, and movable in the axial direction relative to each other. At least one transducer (3, 23; 4, 24) is provided for determining rotational, and optionally axial, forces as a result of the relative motion in order to assess the characteristics of material (7, 27) within the vessel (5, 25). <IMAGE>
Patent NZ-335093-A (NZ)
Title: Cooked or precooked noodle which has been dipped into acidified water and oiled
Inventor: MEYER PHILIPP PAUL
IPC: A23L7/109
Filed: 1999-04-09
Abstract: Full moisture shelf stable noodle product having a pH of from 3.7 to 4.5, and comprising a cooked or precooked noodle having a dry matter content of from 30 to 45% by weight, an acid and an oil.
Patent NZ-336993-A (NZ)
Title: Semi synthetic statins (simvastatin) derived from lovastatin
Inventor: VRIES TON RENE
IPC: C07D327/10
Filed: 1998-01-27
Abstract: A process has been provided to produce semi-synthetic statins defined as Formula I. It is known that certain mevalonate derivatives are active as hypercholesterolemic agents, which function by limiting cholesterol biosynthesis by inhibiting the enzyme HMG-CoA reductase. These mevalonate derivatives are natural occurring fungal metabolites lovastatin and compactin. The process provides for the precursor lovastatin contaminated with dihydrolovastatin to be converted to simvastatin. The naturally occurring compound lovastatin and compactin possess a 2-methylbutyrate side chain in the 8-position of the hexahydronaphtalene ring system. Analogs with a 2,2-dimethylbutyrate moiety in this position, such as simvastatin, appeared to be more effective inhibitors of HMG-CoA reductase.  There are two possible routes for the introduction of an extra a-methyl group in the 8-acyl side chain which are:  1. direct alkylation of the 2 methylbutyrate side chain 2. removal of the 2-methylbutyrate side chain and introduction of a 2,2-dimethyl butyrate chain. The constituents of Formula I are as follows: R1 and R2 selected from H, OH, C1-10alkyl and C6-14aryl and C6-14arylC1-3alkyl; R3 is R9-C=O or hydrogen; R9, R4 and R5 are: 1. C1-15 alkyl 2. C3-15cycloalkyl 3. C2-15 alkenyl 4. C2-15alkynyl 5. Phenyl 6. PhenylC1-6alkyl R9 may also be halogen, C1-6alkyl, C1-6alkoxy and C6-14aryl R4 and R5 may also be 5, 6 or 7 membered heterocycle moiety such as pyrrolidine, piperidine or a homopiperidine R6 and R7 are selected from: 1. dioxane moiety 2. cyclic sulfate 3. cyclic phosphate
Patent NZ-337700-A (NZ)
Title: Prenatal diagnostic methods by separating maternal from fetal blood using conventional chromatographis techniques followed by typing fetal blood for genatic defects
Inventor: BURCHELL ANN
IPC: A61K35/18
Filed: 1998-03-03
Abstract: A method of identifying embryonic or fetal red blood cells in a sample containing maternal blood cells and embryonic or fetal red blood cells or both, the method comprising determining which cell or cells contain or express and adult liver component, wherein the adult liver component is not transferrin receptor. A method of isolating embryonic or fetal red blood cells from a sample containing maternal blood cells and embryonic or fetal red blood cells or both, the method comprising isolating the cells which contain or express an adult liver component. A method of determining a fetal abnormality the method comprising identifying or isolating embryonic or fetal cells according to the above methods and analysing said embryonic or early fetal cells for abnormality. Use of a means for determining whether a cell contains or expresses an adult liver component for identifying or isolating an embryonic or fetal red blood cell.
Patent NZ-338003-A (NZ)
Title: Retroviral protease inhibiting compounds
Inventor: SHAM HING L
IPC: C07D277/34
Filed: 1996-12-06
Abstract: A use, in the preparation of a medicament for inhibiting HIV protease, of a compound of formula I, is disclosed. The use of a compound of formula I in combination with a reverse transcriptase inhibitor or a combination of reverse transcriptase inhibitors, in the preparation of a medicament for inhibiting an HIV infection is also disclosed. Further, a use, in the preparation of a medicament for inhibiting an HIV infection, of a pharmaceutically acceptable salt, ester or prodrug of the compound (2S, 3S, 5S)-2-(2,6-dimethylphenoxyacetyl) amino-3-hydroxy-5-(2S-(1-tetrahydropyrimi-2-only)-3-methyl butanoyl) amino-1,6-diphenylhexane; in combination with another HIV protease inhibitor or a combination if HIV protease inhibitors is disclosed.
Patent NZ-502375-A (NZ)
Title: The addition of non-natural cysteine derivatives to cause the protein to act as antagonists of the GH family
Inventor: COX GEORGE N
IPC: C07K14/475
Filed: 1998-07-13
Abstract: A cysteine variant of a member of the growth hormone (GH) family, comprising a non-natural cysteine residue added preceding the N-terminal amino acid of the mature protein or following the C-terminal amino acid of the protein. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby.
Patent NZ-502656-A (NZ)
Title: Piston coffee maker for preparing coffee in small amounts
Inventor: JOERGENSEN CARSTEN
IPC: A47J31/38
Filed: 1998-08-07
Abstract: Provided is a piston coffee maker where small portions for a single cup of coffee can be made, and where the piston coffee maker is capable of keeping the temperature of the infusion fluid on a suitable level during the preparation of the coffee.  The piston coffee maker (1) includes a cylindrical container (2), a lid (3), a piston (5) with piston rod (7) and a handle (8), where the piston is made as a filter (6) for the ground coffee.  The wall, lid and the bottom of the cylindrical container having double walls so as to insulate the contents of the cylinder.  The upper rim is equipped with a locking means (9), and the lid is provided with corresponding locking means such that the lid can be sealably locked onto the piston coffee maker (1).
Patent NZ-509053-A (NZ)
Title: Process for the preparation of an edible (proteinaceous) substance made from fungal cells of the order Mucorales
Inventor: KRUYSSEN FREDERICUS JOHANNES
IPC: A23L1/28
Filed: 1999-09-15
Abstract: The preparation of a proteinaceous substance suitable for use in a foodstuff is described which comprises fungal fells of the order Mucorales.  The cells are grown in a fermentor vessel in a liquid which is mixed during fermentation, after which the RNA content of the fungal cells is reduced to below 4% and the fungal cells processed into an edible substance.  This substance is then mechanically texturised into edible textured product for inclusion into foodstuffs, for example in the form of chunks as a meat substitute.
Patent NZ-511115-A (NZ)
Title: A neuropilin and vascular endothelial growth factor (VEGF) complex and uses thereof in hibitng bioactiviy of growth factors in tumor cells
Inventor: ALITALO KARI
IPC: C12N5/0783
Filed: 1999-10-19
Abstract: An isolated ligand-receptor complex is described wherein the ligand comprises a polypeptide that binds to NP-1 receptor and has at least 95% sequence identity with the amino acid sequence encoded by exon 6B of VEGF-B167 and the receptor comprises a polypeptide that has at least 95% sequence identity with the extracellular domain of NP-1 and binds to VEGF-B167 or VEGF-C or wherein the ligand is selected from VEGF-B167, processed VEGF-B167, VEGF-C and VEGF-D, and the receptor comprises a polypeptide that binds to VEGF-B167, processed VEGF-B167 or VEGF-C and has at least 95% sequence identity to the extracellular domain of NP-1. Polypeptides comprising the amino acid sequence encoded by exon 6B of VEGF-B167 can be used in the manufacture of a medicament for inhibiting bioactivity of a growth factor selected from to VEGF-B167, processed VEGF-B167, VEGF-C and VEGF-D. Uses and methods for modulating the responsiveness of cells to collapsing/semaphoring glycoproteins and for inhibitng growth or proliferation of tumor cells, and antibodies and vectors are also described.
Patent NZ-513373-A (NZ)
Title: Brain-derived alkali-soluble immunoregulatory composition
Inventor: LINDSEY J WILLIAM
IPC: A61K35/30
Filed: 2000-02-04
Abstract: Described is an active factor present in homogenized brain tissue which inhibits antigen-driven proliferation of lymphocytes in culture, but stimulates proliferation in response to most mitogens. The inhibitory activity can be destroyed by treatment with proteases or neuraminadase. The activity is in the insoluble fraction of the homogenate, but becomes soluble in 0.04 M NaOH. After gel filtration chromatography of the NaOH soluble material, the suppressive activity is in the high molecular weight fraction which elutes in the void volume of the column. This fraction contains protein and carbohydrate. The activity is not affected by neutralizing antibodies against regulatory cytokines, does not depend on Fas or FasL, and is not due to the presence of gangliosides. These data suggest that a brain glycoprotein which is either membrane-bound or part of the extracellular matrix has powerful immune regulatory effects in culture.
Patent NZ-515332-A (NZ)
Title: Lawsonia derived gene and related SodC polypeptides, peptides and proteins and their uses
Inventor: ANKENBAUER ROBERT
IPC: C12P21/08
Filed: 2000-05-11
Abstract: An isolated immunogenic polypeptide comprising a Lawsonia spp. SodC polypeptide which mimics or cross-reacts with a B-cell or T-cell epitope of a Lawsonia spp. SodC polypeptide. Also covered is the use of said polypeptide in a vaccine to produce antibodies against said Lawsonia spp. when it is administered to an avian or porcine animal, and uses of the antibodies to said polypeptide for diagnosing a Lawsonia infection in a porcine or avian animal.
Patent NZ-516098-A (NZ)
Title: Systems and methods for aerosolizing pharmaceutical formulations
Inventor: SCHULER CARLOS
IPC: A61M15/00
Filed: 2000-06-29
Abstract: A method for aerosolizing a pharmaceutical formulation is provided, the method comprising: preventing respiratory gases from flowing to the lungs when attempting to inhale, and then abruptly permitting respiratory gases to flow to the lungs after a threshold actuating vacuum has been reached, wherein the threshold actuating vacuum is in a range from about 20 cm H2O to about 60 cm H2O; and using the flow of respiratory gases to extract a pharmaceutical formulation from a receptacle (760) and to place the pharmaceutical formulation within the flow of respiratory gases to form an aerosol.
Patent NZ-516523-A (NZ)
Title: Method of converting a stream of databits of a binary information signal into a stream of databits of a constrained binary channel signal, device for encoding, signal comprising a stream of databits of a constrained binary channel signal, record carrier, method for decoding, device for decoding
Inventor: COENE WILLEM MARIE JULIA MARCE
IPC: H03M7/14
Filed: 2001-04-20
Abstract: A method of converting a stream of databits of a binary information signal into a stream of databits of a constrained binary channel signal, this signal being constructed by repetitively or alternate using a channel code C1 and a channel code C2. Due to the fact that two channel words with opposite parities are available in the channel code C2 for each information word, and that the same state is established, predetermined properties of the constrained binary channel signal can be influenced, e.g. for performing guaranteed DC-control, i.e. independent of the contents of the stream of databits of the binary information signal. Due to the fact that the method further comprises the step of substituting, in dependence upon a value of a predetermined property of the binary channel signal, a channel word for a substitute channel word, wherein the substituted channel word and the substitute channel word establish the same state, predetermined properties of the constrained binary channel signal can be further influenced. The invention further relates to a device for encoding, a signal, a record carrier, a method for decoding and a device for decoding.
Patent NZ-516708-A (NZ)
Title: Improvements relating to furniture
Inventor: GARLICK STEPHEN JAMES
IPC: A47C7/64
Filed: 2002-01-18
Abstract: A support hanger assembly adapted to be fitted or arranged for fitment to the rear face of a backrest of a seat, wherein the backrest comprises a rear and forward face, the forward face against which a user's back can rest when seated, the assembly being characterized in that it comprises: a support means movable between a first stowed and/or non-usable position recessed within or in close proximity to the rear face f the backrest; a second usable position projecting from the backrest; wherein when in use the support means hinges outwards form the first position and is extended to an outwards and upwards second usable position and wherein the assembly is adapted when in use to support the garment.
Patent NZ-517035-A (NZ)
Title: A composition and formulation for drug delivery comprising a block copolymer wherein the amount of poly(alkylene oxide) blocks is within a range of 2.5-80%
Inventor: SEO MIN-HYO
IPC: A61K9/50
Filed: 2000-07-18
Abstract: Compositions and formulations for drug delivery comprising a biocompatible and biodegradable block copolymer of poly(alkylene oxide) and poly(p-dioxanone) are described. The block copolymer described, which is soluble in pharmaceutically acceptable solvents, comprises one or more poly (alkylene oxide) blocks and one or more blocks of a p-dioxanone homopolymer or copolymer, wherein the amount of the poly (alkylene oxide) blocks is within a range of 25 to 80% by weight, based on the total amount of the block copolymer.
Patent NZ-520022-A (NZ)
Title: Protein and DNA sequences for XYL-IV from Trichoderma reesei
Inventor: SALOHEIMO MARKKU L A
IPC: C12Q1/68
Filed: 2000-09-11
Abstract: Xylanases proteins designated XYL-IV derived from microorganisms are described. The protein can comprise the amino acid sequence of SEQ ID NO:2 and the mature polypeptide is encoded by the cDNA sequence of SEQ ID NO:1. Preferably the microorganism is the filamentous fungus Trichoderma reesei. Methods of producing an XYL-IV protein, vectors cells and antibodies that bind the protein are described. The protein can be used to alter the properties of xylan containing substrate, such as altering the handling properties of animal feed, food properties and plant materials, altering the properties of wood pulp or derivatives during the manufacture of paper and altering the properties of xylan containing biomass during its reduction to glucose.
Patent NZ-520099-A (NZ)
Title: Systems and methods for reducing intraocular pressure
Inventor: COTE DANA
IPC: A61F2/14
Filed: 2001-01-05
Abstract: Disclosed are systems and methods for reducing intraocular pressure, thereby to treat glaucoma and other disorders. The systems of the present invention include a shunt insertable across the clear cornea and a delivery device for inserting the shunt in the transcorneal position. The shunt has a body with a head at one end and a foot at the opposite end, and a channel therethrough permitting the passage of aqueous humor from the anterior chamber to the external surface of the cornea. A removable filter is positioned within the channel to regulate aqueous humor outflow and to resist the incursion of microorganisms.