baber/WOPTO huggingface dataset:
Patent AU-2019240135-A1 (AU)
Title: Separation of VWF and VWF propeptide by chromatographic methods
Inventor: FIEDLER CHRISTIAN
IPC: C07K14/435
Filed: 2019-03-20
Abstract: The present invention relates to a method for separating a mature von Willebrand Factor (mat-VWF) from von Willebrand Factor pro-peptide (VWF-PP) by incubating a composition comprising inducing dissociation of mat-VWF and VWF-PP by disruption of the non- covalently associated mat-VWF and VWF-PP, wherein said dissociation is induced by: (i) addition of at least one chelating agent, or (ii) increasing the pH to a pH of at least 7, and then collecting said mat-VWF to obtain a high purity, propeptide depleted mature VWF (mat- VWF).
Patent AU-2019246781-A1 (AU)
Title: Use of a CD6 binding partner and method based thereon
Inventor: NAIR PRADIP
IPC: A61K39/395
Filed: 2019-10-08
Abstract: Abstract The present disclosure relates to methods for treatment and prevention of disease conditions mediated by T-helper 17 (Thl7) and/or T-helper 1 (Thl) T lymphocytes (T cells). In particular, the present disclosure relates to use of anti-CD6 antibody for treatment of disease conditions mediated by auto-reactive Thl7 and Th1 T lymphocytes. The methods of the present disclosure further have utility in methods for modulating an immune response by suppressing production of the cytokine IL-23R, thereby decreasing inflammation mediated by Thl7 cells.
Patent AU-2019255227-A1 (AU)
Title: System and methods for changing addresses of one or more components
Inventor: BUSH STEPHEN P
IPC: G06F3/00
Filed: 2019-04-16
Abstract: A method of determining addresses for a plurality of components includes receiving, by a slave device, an address change request from a master device. The slave device may be one of the plurality of components or a security module separate from the master device. In response to the received address change request received, a pseudorandom number generator (PRNG) state is updated based on a previous state thereof. The method further includes, retrieving, for each component, a set of bits from the PRNG state to form a candidate address for the component and determining a new component address for the component based on the candidate address. As a result, new component addresses of the plurality of components are determined based on different sets of bits retrieved from the same PRNG state.
Patent AU-2019262624-A1 (AU)
Title: Perfusion bioreactor with filtration systems
Inventor: LU JIUYI
IPC: C12M1/36
Filed: 2019-05-03
Abstract: The disclosure provides a filtration system for a cell culture apparatus and a method of cell culture. The filtration system comprises a bioreactor vessel and two or more alternating tangential flow (ATF) filters connected in parallel. A failure m either filter is detected by an in-line sensor, and an automated response system functions to sequester the malfunctioning filter by stopping the flow of liquid media through the filter. Media flow through the remaining operable filters can be increased so that the rate of perfusion through the bioreactor remains relatively unchanged. Such a system may prevent issues that arise from ATF filter failures in conventional perfusion bioreactors, thereby improving the long-term viability of cell cultures.
Patent AU-2019272021-A1 (AU)
Title: Repeated administration of non-immunosupressive antigen specific immunotherapeutics
Inventor: MALDONADO ROBERTO A
IPC: A61K31/436
Filed: 2019-11-28
Abstract: This invention relates to repeated administration of antigen- specific immunotherapeutics using protocols, or elements thereof, that do not induce immunosuppression. In some embodiments, the protocol has been previously shown not induce immunosuppression in a subject. See Fig. WO 2014/197616 PCT/US2014/040938 pOVA im. pOVA i. +fMTX i.p. KLH+CpG S.C. 0 7 14 21 28 5000 I I 50000-- ns 4000- 40000_ Md19 Ln El d34 UU E d40 S3000- 09 30000 .L2000 *i 20000 1 000-- 10000 Fig. 2 C T TTl C 'TmPT Tmr C T TT7 T7 U' /T-')T Tl T' I/7
Patent AU-2019275621-A1 (AU)
Title: Adjustable tracheostoma valve and heat and moisture exchanger
Inventor: MARKWARDT NEIL
IPC: A61M16/04
Filed: 2019-12-05
Abstract: An adjustable tracheostoma valve (10) includes a housing (12) having a first opening (18) 
that is adapted to open to a tracheostoma and a second opening (20) that opens to ambient.  
The housing includes a lower housing portion (14) defining the first opening and an upper 
housing portion (16) movably attached to the lower housing portion and defining the second 
opening. A closure member (22) is disposed in the housing and adapted to close the 
second opening. A flexible membrane (24) includes a first region connected to the closure 
member and a plurality of spiral shaped legs extending from the first region and connected 
to the housing. The upper and lower housings are axially adjustable relative to one another 
to adjust an amount of air flow through the valve that would cause closure of the closure 
member. A heat and moisture exchanger is disposed in the housing between the first 
opening and the second opening.  
FIG. 1.
1/8 
20 2 
24 
16 
56 
12 
14 
FIG. 1 
56 
;10 
16 
12 
14 
26 
18 32 
FIG. 2
Patent AU-2019283778-A1 (AU)
Title: Conjugates of an IL-15 moiety and a polymer
Inventor: LIU XIAOFENG
IPC: C07K14/54
Filed: 2019-12-16
Abstract: Abstract Conjugates of an IL-15 moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the nonpeptidic, water-soluble polymer is poly(ethylene glycol) 5 or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to an individual. 11963632_1 (GHMatters) P104071.AU.1 13/12/19
Patent AU-2019285316-A1 (AU)
Title: Method and device for determining the particle emission coefficient and potential of a material, and a method for controlling a traffic lane
Inventor: SEDIKI OUARDIA
IPC: G01N1/10
Filed: 2019-06-14
Abstract: Method for determining the particle emission coefficient of a material (CE), comprising the steps of: b) successively, for different masses of fines: b1) disposing a mass of said fines in a chamber (10); b2) and, by injecting air into the chamber (10), ejecting the particles from the chamber in an outgoing air flow; b3) measuring the maximum mass concentration (PM_max) of the particles in the outgoing air flow and the total ejection time (D_Ej) of the particles; d) calculating a trend line (D) that is representative of the function providing the maximum standardised particle concentration (PM_max_norm) as a function of the standardised ejection time (D_Ej_norm) of the particles; e) calculating the particle emission coefficient of the material (CE) according to the slope of the trend line (D).
Patent AU-2019292471-A1 (AU)
Title: Merge mode-based inter-prediction method and apparatus
Inventor: KIM KI BAEK
IPC: H04N19/587
Filed: 2019-07-01
Abstract: The present invention relates to a video encoding/decoding method and apparatus, comprising the steps of: establishing a merge candidate list of a current block; deriving motion information of the current block from the merge candidate list; and carrying out inter-prediction on the current block by using the motion information, wherein the merge candidate list includes at least one among a spatial merge candidate, a temporal merge candidate, and a combined merge candidate, and the combined merge candidate is derived by combining a number n of merge candidates which belong to the merge candidate list. The present invention has the effect of increasing the accuracy of motion information by using a combined merge candidate as well as a spatial/temporal merge candidate.
Patent AU-2019296308-A1 (AU)
Title: Memory access window and padding for motion vector refinement and motion compensation
Inventor: ESENLIK SEMIH
IPC: H04N19/56
Filed: 2019-06-28
Abstract: Method and apparatus for motion vector determination using template or bilateral matching and predictor generation based on the motion vector. The template or bilateral matching and/or the predictor generation use interpolation filtering. The interpolation filtering operation accesses integer sample positions within a window, and further uses padded sample values for integer sample positions outside the window, which are based on at least one sample within said window, and uses the accessed integer sample position values as well as the padded sample values to perform the template or bilateral matching and/or predictor generation.
Patent AU-2019336254-A1 (AU)
Title: Device for suture attachment for minimally invasive heart valve repair
Inventor: CAFFES LEVI
IPC: A61B17/29
Filed: 2019-09-09
Abstract: Disclosed herein are minimally invasive systems and methods for intravascularly accessing the heart and performing a transcatheter repair of a heart valve by inserting a suture as an artificial chordae into a heart valve leaflet. In various embodiments, such systems and methods can be employed in other heart valve repair procedures such an edge to edge repair to coapt leaflets by inserting one or more sutures that retain the leaflets in a coapted positioned or inserting a suture to repair a tear in a leaflet, for example.
Patent AU-2019354391-A1 (AU)
Title: Compositions and methods regarding engineered and non- engineered γδ-Τ cells for treatment of hematological tumors
Inventor: SATPAYEV DAULET KADYL
IPC: A61K39/00
Filed: 2019-10-01
Abstract: Aspects of the invention include compositions and methods for treatment of hematological tumors with engineered or non-engineered γδ-T cells. In some embodiments, the γδ-T cells comprise a chimeric antigen receptor (CAR) construct. The CAR construct can contain an anti-CD20 binding domain or anti-B cell maturation antigen (BCMA) binding domain, a CD8 hinge and transmembrane domain, a costimulatory domain, a CD3 ζ signalling domain, a combination thereof, or all thereof. The CAR construct can contain a domain encoding for a secreted common gamma chain cytokine such as a sIL15 domain.
Patent AU-2019369210-A1 (AU)
Title: Interference protection device and method for hydraulic support and cutting part of shearer
Inventor: WANG ZHONGBIN
IPC: E21C35/00
Filed: 2019-06-18
Abstract: Disclosed is an interference protection device and method for a hydraulic support and a 
cutting part of a shearer. The device includes: a plurality of dust-proof cases evenly and 
fixedly provided on a surface of one side of a hauling part of the shearer that faces away from 
a coal wall, and a dust-proof housing fixed on the hydraulic support. A first ultrasonic 
transducer and a flash lamp are fixedly provided in each dust-proof case, and a second 
ultrasonic transducer, a receiver, and a data processing module are fixedly provided in the 
dust-proof housing. The data processing module is electrically connected to the second 
ultrasonic transducer and the receiver separately, the first ultrasonic transducers and the flash 
lamps are all electrically connected to an external single-chip microcomputer, and the data 
processing module is electrically connected to a hydraulic support control computer. The 
present invention obtains a distance from the shearer to the hydraulic support by calculation 
from a difference between time points at which the second ultrasonic transducer and the 
receiver on the hydraulic support respectively receive an ultrasonic signal and an optical 
signal, and thus timely controls a guard plate to retract, thereby achieving the advantages of 
low cost, high applicability and high reliability.
Patent AU-2019380871-A1 (AU)
Title: Vehicle Door System
Inventor: BESSEL MITCHELL PENNING
IPC: E05F15/56
Filed: 2019-11-15
Abstract: A mechanism to enable opening and closing of a vehicle door comprising a swing arm assembly in use pivotally coupled between a vehicle structure and a slide support carriage. The slide support carriage being mounted to an elongate rail assembly attached to the vehicle door for movement there along. The mechanism further comprises a motion control surface attached to or integral with the door assembly and a follower assembly to regulate relative simultaneous pivotal motion of the swing arm according to the position and motion of the slide support carriage along the rail assembly.
Patent AU-2019440079-A1 (AU)
Title: Automatic image capture
Inventor: CAO LEI
IPC: H04N5/232
Filed: 2019-04-01
Abstract: Methods and systems for automatic image capture are described herein. A user device may determine a reference orientation of the user device. The user device may monitor orientations of the user device as the user device is moved and/or rotated. Based on the reference orientation and the monitored orientations, the user device may determine to automatically capture images. The user device may organize captured images into a file for storing and/or sharing.
Patent AU-2020202870-A1 (AU)
Title: Method and apparatus for displaying picture on portable device
Inventor: BAE DAEWOONG
IPC: G06F3/048
Filed: 2020-04-30
Abstract: Abstract A method for a portable device having a touch screen display, the method comprising: displaying, in full mode, an original screen on the whole of the touch screen display, the original screen comprising one or more application icons; entering, in response to detecting a preset input event, a mini-mode in which a reduced size image of the original image is displayed on a partial area of the touch screen, the reduced size image having reduced size versions of the one or more application icons in the same arrangement as the original image, and when an application icon of the reduced size image is selected by a user touch, a corresponding application is executed; wherein a plurality of further icons are displayed on the outside of one side of the reduced size image when in the mini-mode, the plurality of further icons being displayed in a first order from left to right when the reduced size image is located on the left of the touch screen, and the plurality of icons being displayed in a second order from left to right when the reduced size image is located on the right of the touch screen, wherein the first order is the reverse of the second order. 12307934_1 (GHMatters) P101326.AU.1 [Fig. 2] DISPLAY ORIGINAL IMAGE 201 DETECT PRIEST EIONT Y PERFORM THE CORRESPONDING FUNCTION NO DEACTIVATMINI-MDE 3 ENTER MINI-MODE AND DISPLAY MIRROR IMAGE 208 DETECT TOUCH INPUT FOR NO DETECT TOUCH IN PUT FOR NO FUNCTION ON MIRROR IMAGES MIRROR IMAGE SETUP CHANGEP., PERFORM SELECTED FUNCTION AND DISPLAY CHNEMIRROR IMAGE SETUP AND DISPLAY NO DEACTIVATE MINI-MODEP 230
Patent AU-2020203327-A1 (AU)
Title: A bladder device for light bladder leakage
Inventor: CLAPPERS JAMES EDWARD
IPC: A61F2/00
Filed: 2020-05-21
Abstract: : 
The present invention relates to a device for treating light bladder leakage in a human. In particular 
the present invention relates to a device which is effective for use by sufferers of lightbladder 
leakage urinary incontinence to substantiallyminimize symptoms of light bladder leakage. The 
device having: a. holding member having a resilient deformable shaped body which is sized and 
resilience to fit within the user's vagina and resiliently return to provide a holding force; b. removing 
grip attached tothe holding member.
2/5 
11 16 
11 
14 
12 
5 
18 
13 
20 
21a 
21 
19 
Figure 2 Figure 3 
11 17 17 
16 14 
15 
12 
18 
13 20 
19 21 
Figure 4 Figure 5
Patent AU-2020204410-A1 (AU)
Title: Transgenic mice expressing chimeric major histocompatibility complex (mhc) class i molecules
Inventor: MACDONALD LYNN
IPC: A01K67/027
Filed: 2020-07-01
Abstract: The invention provides genetically modified non-human animals that express chimeric 
human/non-human MHC I polypeptide and/or human or humanized P 2 microglobulin 
polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are 
constructs for making said genetically modified animals and methods of making the same.  
Methods of using the genetically modified animals to study various aspects of human 
immune system are provided.
Patent AU-2020207935-A1 (AU)
Title: Dynamic pharmacokinetic-modifying anchors
Inventor: KHVOROVA ANASTASIA
IPC: C12N15/113
Filed: 2020-01-17
Abstract: Therapeutic oligonucleotides comprising pharmacokinetic (PK)-modifying anchors are provided. Methods for treating diseases or disorders comprising administering to a subject a therapeutic oligonucleotide comprising one or more PK-modifying anchors are provided.
Patent AU-2020219125-A1 (AU)
Title: Isolated cell culture components and methods for isolating the same from liquid cell culture medium
Inventor: BITTERFIELD DEBORAH LEE
IPC: C12M1/32
Filed: 2020-02-05
Abstract: Described herein are isolated cell culture components such as, e.g., biologics and/or lipids, and methods for isolating cell culture components from a liquid cell culture medium. Methods of the present invention may include contacting a dehydration composition and a liquid cell culture medium comprising a target component to form a mixture; forming an at least partially dehydrated component in the mixture; and separating the at least partially dehydrated component from the mixture, thereby providing an isolated component. In some embodiments, the isolated component comprises the at least partially dehydrated component. In some embodiments, the isolated component is present in a composition (e.g., liquid phase) separated from the at least partially dehydrated component.
Patent AU-2020225202-A1 (AU)
Title: Therapeutic antibody formulation
Inventor: CORVARI VINCENT JOHN
IPC: C07K16/24
Filed: 2020-02-11
Abstract: Stable aqueous pharmaceutical formulations for therapeutic antibodies and methods of using such stable aqueous pharmaceutical formulations.
Patent AU-2020230342-A1 (AU)
Title: Vortex Drag Disruption Apparatus
Inventor: STINCHCOMB JOSEPH
IPC: B62D35/00
Filed: 2020-09-11
Abstract: VORTEX DRAG DISRUPTION SYSTEM 
A vortex disruption system for vehicles is disclosed, having a plurality of vortex disruption devices 10 
5 mounted to roof and/or sides of the vehicle in spaced relation with the vehicle rear end. The vortex 
disruption devices 10 include a leading end 12, a trailing end 14, and a bottom 20 defining an isosceles 
triangular, left-hand and right-hand planar surfaces 16, which originate at leading end 12 and extend in 
diverging and inwardly slanted relation joining along a common upper edge 18. Trailing end 14 of the 
devices 10, when incorporated onto a vehicle, extends beyond the fluid dynamic boundary layer formed as 
0 the vehicle moves through the air. The bottom 20 includes a transverse recess 22 and a pair of slotted 
apertures 14 for removable retrofitting of a plurality of devices 10 to roof and/or sides of the vehicle by a 
strap. Alternatively, they can be permanently retrofitted, or built into design of the vehicle.  
11
ID
FIG.12
Patent AU-2020234111-A1 (AU)
Title: Small shedding blocking agents
Inventor: HAKIM MOTTI
IPC: C07K16/28
Filed: 2020-03-12
Abstract: Agents that are less than 100 kilodaltons, bind a membranal immune receptor on a surface of a cell and inhibit proteolytic cleavage of the immune receptor are provided. Methods of treating cancer and improving immunotherapy comprising administering the agents are also provided.
Patent AU-2020249598-A1 (AU)
Title: Mage A4 T cell receptors
Inventor: ELLINGER CHRISTIAN
IPC: C07K14/725
Filed: 2020-03-27
Abstract: The present invention relates to an isolated T cell receptor (TCR) specific for MAGE-A4 and a polypeptide comprising a functional portion of the TCR. Further implicated are a multivalent TCR complex, a nucleic acid encoding a TCR, a cell expressing the TCR and a pharmaceutical composition comprising the TCR. The invention also refers to the TCR for use as a medicament, in particular to the TCR for use in the treatment of cancer.
Patent AU-2020334361-A1 (AU)
Title: Insert block
Inventor: JARVIE JOHN MICHAEL
IPC: F16B4/00
Filed: 2020-08-24
Abstract: Disclosed is an insert block for a composite polymer/fibre section. The insert block is formed from a high-density polymer and is configured such that, in use, the insert block is able to closely interface with at least two opposing walls of the composite polymer/fibre section. The insert block is also configured such that it is able to substantially fill a hollow space defined between the at least two opposing walls of the composite polymer/fibre section. In use, when a force is applied to the adjacent portion of the composite polymer/fibre section, the force is able to transfer into the insert block.
Patent AU-2020335999-A1 (AU)
Title: Fluid distribution assembly
Inventor: STRASHNY IGOR
IPC: E02F9/00
Filed: 2020-08-17
Abstract: The present disclosure is directed towards a fluid distribution assembly (28). The fluid distribution assembly (28) comprises a distribution device (100) comprising at least one device inlet (104) for receiving fluid and at least one device outlet (105) for directing fluid out of the distribution device (100). The fluid distribution assembly (28) comprises at least one distribution plate (101, 102) adjacent to the distribution device (100) comprising at least one distribution arrangement (120, 121, 122, 124) for controlling the communication of fluid to and/or from the at least one device inlet and/or outlet (104, 105).
Patent AU-2020339069-A1 (AU)
Title: Air-conditioning system for a vehicle
Inventor: BOECK LUTZ
IPC: B61D27/00
Filed: 2020-08-18
Abstract: The invention relates to an air-conditioning system for a rail vehicle, wherein the air-conditioning system is suitable for flammable refrigerants of categories A2, A2L and A3, is designed in the form of a compact piece of equipment for installation on the vehicle roof and at least has equipment sections for air treatment, section B, and a compressor-liquefier unit, section D, and optionally an outgoing air section A and/or an electrical switchbox C and/or silencer. The problem addressed by the invention is that of realising, for an air-conditioning system of this kind, a direct evaporating system, in which the air to be conditioned for the passenger area is sealed off within the air-conditioning system such that, in the event of leaks at refrigerant-conducting assemblies, ingress of flammable refrigerant into the interior of the vehicle is prevented. This problem is solved in that the refrigerant-conducting assemblies and components are located outside the areas where comfort air is conducted, in a separate housing and open to the surroundings, namely in that at least the mixed-air flaps (2) for outside air/ambient air, an air filter (3), the supply-air flaps (7), a supply-air fan (4), an evaporator (5), a heat register (6) of the air treatment section (B) and interfaces thereof to the outside air intake (a) and/or to the ambient air intake (b) and to the supply-air blow-out (e1 and/or e2) are located within air-tight or pressure-tight ducting in the housing of the air-conditioning system, which air-conditioning system is designed in the form of a compact piece of equipment.
Patent AU-2020352900-A1 (AU)
Title: Scalable Nesting SEI Messages For OLSs
Inventor: WANG YE-KUI
IPC: H04N13/00
Filed: 2020-09-11
Abstract: A video coding mechanism is disclosed. The mechanism includes receiving a bitstream comprising one or more layers and a scalable nesting supplemental enhancement information (SEI) message. The scalable nesting SEI message includes one or more scalable-nested SEI messages and a scalable nesting output layer set (OLS) flag. The scalable nesting OLS flag is set to specify whether the scalable-nested SEI messages apply to specific OLSs or specific layers. A coded picture is decoded from the one or more layers to produce a decoded picture. The decoded picture is forwarded for display as part of a decoded video sequence.