baber/WOPTO huggingface dataset:
Patent DK-0845476-T3 (DK)
Inventor: SPROAT BRIAN DR
IPC: C12Q1/68
Filed: 1992-06-17
Granted: 2001-06-25
Abstract: Synthetic catalytic oligonucleotide structure (I) comprising nucleotide units having a hydroxy or alkoxy group in the 2' position, provided that the nucleotide units in the catalytically active center have 2'-hydroxy groups, is new (N.B. it is implied but not stated that the other nucleotide units have 2'-alkoxy groups). Synthetic catalytic oligonucleotide structure (I) comprising at least one nucleotide of formula (II) is new: B' = a nucleobase; V' = O or CH2; X, W' = O, S, NH2, 1-10C alkyl or 1-10C alkoxy; and R = H or 1-10C alkyl; provided that the nucleotides in the catalytically active center have R = H. Independent claims are also included for the following: (1) a method for cleaving a target nucleic acid sequence using (I); (2) a medicament comprising (I) and optionally carriers, excipients, fillers and/or diluents; (3) a diagnostic reagent containing (I) as a component; (4) a catalytic hammerhead oligonucleotide of formula (III); (5) a catalytic hammerhead oligonucleotide of formula (IV); and (6) use of (III) or (IV) to cleave a target nucleic acid sequence of formula (V): N, N0-N14 = nucleotides of formula (II); provided that in; N1, N4, N8, N10 and N11, R = H; and in N2, N3, N5, N6, N7, N9, N12, N13 and N14; R = alkyl; and that N5 and N6 are complementary to each other; x = 1 or more; y = 2 or more; N', N = (a) two nucleotide sequences consisting at least partly of complementary nucleotides to provide stable base pairing between the sequences; or together, N' and N = a single nucleotide sequence, at least part of which can form a double-stranded stem through base pairing of complementary nucleotides; M = a chemical bond or a nucleotide sequence (N)a; a, m, n = 1 or more U = uridine; Z = A, C or U; K, Y = any nucleotides; and b = 3 or more.
Patent DK-0810223-T3 (DK)
Inventor: LYSSIKATOS JOSEPH PETER
IPC: A61P43/00
Filed: 1997-05-16
Granted: 2001-09-24
Abstract: This invention relates to a method of treating cancer by administering a compound of the formula <CHEM>  or <CHEM> wherein R<1>, R<2>, R<3>, R<4>, R<5>, E<1>, E<2>, p, Het' and Het" are defined as indicated in the specification.
Patent DK-0897726-T3 (DK)
Inventor: NAGASE HIROSHI
IPC: A61K31/541
Filed: 1997-11-21
Granted: 2007-08-13
Abstract: This invention provides an antipruritic comprising an opiate K receptor agonist as an effective component, and morphinian derivatives which are useful for the treatment of pruritus caused by various diseases.
Patent DK-0894312-T3 (DK)
Inventor: TUSHIE DAVID R
IPC: G06Q40/00
Filed: 1997-04-14
Granted: 2003-07-21
Abstract: A smart card personalization system maintains a database containing card issuer data format templates, card applications, card operating system commands, and personalization equipment specifications and provides a centralized interface of inputs and outputs to a card issuing process which dynamically adjusts to changes in the issuing process to easily permit a card issuer to change data formats, card applications, card operating systems and/or personalization equipment in a card issuing process. The system interfaces to any card issuer management system, manages the transfer of cardholder data and card applications to the particular personalization equipment used, and maintains statistics for real-time and off-line inquiries to support critical management and reporting functions. Furthermore, the system works with a variety of security methodologies to prevent fraud.
Patent DK-0910531-T3 (DK)
Inventor: GRIMM FRIEDRICH
IPC: B62M6/60
Filed: 1997-07-08
Granted: 2000-06-13
Abstract: The invention relates to a single-track two-wheeled vehicle, in particular a bicycle, electric bicycle, electric scooter or motor scooter. The vehicle comprises a front section and a rear section which are both pivotably connected to each other by a pivot mechanism (1-4) arranged substantially centrally between the front and the rear wheel. The front section comprises a front wheel suspension with the front wheel (11), a handlebar (21) offset towards the front in relation to the pivot mechanism (1-4), and a connection member (21') of the handlebar (21). The rear section comprises a rear wheel suspension with the rear wheel (10) and a saddle support (26') on which the saddle (26) is mounted. A drive unit (40-53) is provided which is either part of the front section or the rear section, the front wheel suspension and the connection member (21') on which the handlebar (21) is mounted forming a first unit which cannot be rotated. The rear wheel suspension and the saddle support (26') form a second unit which cannot be rotated, the saddle (26) being offset to the rear in relation to the pivot mechanism (1-4), and the drive unit (40-53) acting either on the front wheel (11) or the rear wheel (10).
Patent DK-0896111-T3 (DK)
Inventor: SCHUERMANN WOLFRAM
IPC: E04D13/14
Filed: 1998-08-08
Granted: 2000-07-17
Abstract: The passage (10) is used through a roof, and comprises a roof ventilation pipe (11). The roof ventilation pipe has an insulation layer on the pipe surfaces above and/or below the roof. An insulation layer is also at the outer surfaces of the hood (16) and at the upper (19) and/or lower surfaces of the dome (14). The insulating layers are in a multi-layer plastics foam structures, preferably with pores between them to contain air.
Patent DK-0950005-T3 (DK)
Inventor: GAREN RUNE
IPC: B63H5/125
Filed: 1998-01-09
Granted: 2002-07-29
Abstract: A steering and/or propulsion device for a vessel, preferably for installation in the bow portion of the vessel, comprising a propeller nozzle assembly (1) adapted to be rotated 360 DEG  about its vertical axis (2). The propeller/nozzle assembly (1) is provided for two active drive positions, one position (O<N>) below the bottom of the vessel and one position (O<O>) in a preferably downwardly open channel (3) in the bottom portion of the vessel, whereby the direction of the rotational axis of the propeller is coincident with the axis direction or longitudinal direction of the channel. The propeller/nozzle assembly (1) can be reversed also in the upper operative position.
Patent DK-1068196-T3 (DK)
Inventor: DEL SOLDATO PIERO
IPC: A61K31/425
Filed: 1999-02-25
Granted: 2004-11-29
Abstract: Nitrate salt compositions with anti-ulcer medicines having formula (A) and (B) wherein the (A) class compounds: R=H, OCH3, OCHF2; R1=CH3, OCH3; R2=H, CH3; R3=CH3, CH2-CF3, (CH2)3-OCH3; wherein the (B) class compounds: RI3, RI4 equal to or different from each other, are respectively free valence hydrogen, (1), -CH2-N(CH3)2; Y=S, N-RI6, CRI7RI8; X=O, S, N-RI1; RI2=H, CH3; n=0, 1; Z=N-CN, N-SO2NH2, CH-NO2 or formula (VIIA) RI5=H, -NH-CH3, NH2; RI6, RI7, RI8, RI1, equal to or different from each other, are hydrogen, free valence. The invention also comprises the methods for the preparation of above salts.
Patent DK-1084295-T3 (DK)
Inventor: STRUCK OLIVER
IPC: D21H17/67
Filed: 1999-04-26
Granted: 2004-04-26
Abstract: The invention relates to a process for the production of paper from a suspension containing cellulosic fibres, and optional fillers, which comprises adding to the suspension a drainage and/or retention aid comprising a cationic organic polymer, forming and dewatering the suspension on a wire, wherein the cationic organic polymer has an aromatic group and the suspension which is dewatered on the wire has a conductivity of at least 2.0 mS/cm.
Patent ES-2193907-T3 (ES)
Inventor: SCHAFER RALF
IPC: B07B1/20
Filed: 2000-03-25
Granted: 2003-11-16
Abstract: An ejection opening (5) is covered with slotted and/or holed (perforated) sheet metal (6-9).
Patent ES-2257238-T3 (ES)
Title: Aposito para emision controlada de principios activos en heridas y metodo para su fabricacion.
Inventor: BERTHOLD ACHIM DR
IPC: A61M31/00
Filed: 2000-05-20
Granted: 2006-08-01
Abstract: Apósito para herida, para la emisión controlada de principio activo a heridas, en particular de sustancias que favorecen la cicatrización en heridas crónicas de mala cicatrización, caracterizado porque está constituido por capas con el objeto de absorber líquido, con aumento de volumen, en particular para absorber exudado de la herida y contiene dos capas a base de polímero (1, 3), dos capas similares a tejido o fibra no tejida (napa) (2, 4) y por lo menos un principio activo, estando dispuestas las capas (1, 2, 3, 4) alternadas la una sobre la otra y unidas entre sí, con la particularidad de que las capas que contienen polímero (1, 3) contienen como absorbente de líquido un hidrogel hinchable que contiene hidrocoloide.
Patent ES-2245916-T3 (ES)
Inventor: THOMAS PETER
IPC: B62D25/06
Filed: 2000-07-13
Granted: 2006-02-01
Abstract: The vehicle roof has a structure including a guide rail (4) and a roof frame (1). The guide rails and the frame are inside the roof side beam (3) bounding the roof aperture and are connected to it. There is a holding rail (7), e.g. for a roof transporting system, in a deep groove (6) running between the roof side beam and the guide rail.
Patent ES-2228388-T3 (ES)
Title: Valvula fusible de velocidad de freno.
Inventor: DUNBAR SCOTT DAVID
IPC: B60T11/32
Filed: 2000-12-02
Granted: 2005-04-16
Abstract: Un sistema de freno para un vehículo, que tiene válvulas de freno primera y segunda (14, 16), tuberías de freno primera y segunda (20, 22) y una válvula fusible de velocidad (118) para controlar la comunicación entre cada una de las válvulas de freno (14, 16) y una de las tuberías de freno (20, 22) correspondiente, comprendiendo la válvula de fusible de velocidad: (118): un alojamiento (200) de válvula que tiene un ánima (202) de válvula que se extiende a su través, teniendo el alojamiento (200) de válvula una primera entrada (124) comunicada con la primera válvula de freno (14), una segunda entrada (126) comunicada con la segunda válvula de freno (16), una primera salida (128) comunicada con la primera tubería de freno (20) y una segunda salida (130) comunicada con la segunda tubería de freno (22); una primera cámara piloto (222) comunicada con la primera salida (128), una segunda cámara piloto (226) comunicada con la segunda salida (130); un miembro (204) de válvula recibido a deslizamiento en el ánima (202) y que se puede mover en respuesta a una presión de fluido comunicada a las cámaras piloto.
Patent ES-2204453-T3 (ES)
Title: Aglutinante para el recubrimiento del cuero y cuero recubierto que tiene buena capacidad de estampado y buena resistencia a las flexiones repetidas en medio humedo.
Inventor: LESKO PATRICIA MARIE
IPC: C09D157/12
Filed: 2000-01-11
Granted: 2004-05-01
Abstract: Una composición acuosa adecuada para uso en el recubrimiento del cuero que comprende un polímero en emulsión acuosa que comprende de un 0, 4% a un 10% en peso de monómero de acetoacetato o acetoacetamida copolimerizado basado en el peso del mencionado polímero y que presenta una temperatura de transición a la fase vítrea (Tg) de -20º C a 10º C.
Patent ES-2184681-T3 (ES)
Inventor: DUGUET JEAN-RENE
IPC: F23Q3/00
Filed: 2000-02-02
Granted: 2003-04-16
Abstract: The igniter consists of a metal housing (11) with an over-molded cover (13), containing a partition (2) with two electrode pins (9,10) passing through glass cylinders (7,8). The electrode pins are connected by a flat heating resistance (19) with two metal layers (17,18) covered by a pyrotechnic priming compound (20).  The flat heating element is no more than 0.001 mm thick and consists of a metal compound with a volume resistivity of between 0.5 and 2 x 106 Ohm-m, such as bismuth, tantalum nitride, or iron and copper, nickel chrome and phosphorous alloys. The pyrotechnic priming compound is in the form of a paint made from a polyvinyl binding agent and a primary explosive.
Patent ES-2225080-T3 (ES)
Inventor: PADERA JOSEF
IPC: F03G7/08
Filed: 2000-02-07
Granted: 2005-03-16
Abstract: The invention relates to a device for generating electric energy from the kinetic energy of vehicles. Said device comprises at least one pressure reservoir (13) for a fluid. Said pressure reservoir is arranged in the pavement and has at least one pressure chamber that is compressible in a substantially rectangular direction to the pavement, at least one circuit for the fluid, a component of the fluid circuit representing the pressure chamber, and at least one turbine/generator system (86) arranged in the fluid circuit for generating electric energy from the flow of the fluid.
Patent ES-2206276-T3 (ES)
Inventor: LUCONI MICHAELA
IPC: C12N5/076
Filed: 2000-07-25
Granted: 2004-05-16
Abstract: The invention relates to a medium for storage and/or transportation of spermatozoa comprising a phosphatidylinositol-3 kinase (PI3K) inhibitor.
Patent ES-2265997-T3 (ES)
Title: Procedimiento para la preparacion de interleucina-8 y muteinas de interleucina-8 recombinantes y su uso para encontrar antagonistas de receptores de il-8.
Inventor: APELER HEINER
IPC: C12N1/19
Filed: 2000-10-23
Granted: 2007-03-01
Abstract: Uso de IL-8 Y13H en preparaciones de detección sistemática para encontrar antagonistas de IL-8 de bajo y alto peso molecular de los receptores CXCR1 y CXCR2 de IL- 8.
Patent ES-2218245-T3 (ES)
Inventor: DUMARGUE GUY
IPC: B65B55/02
Filed: 2000-10-31
Granted: 2004-11-16
Abstract: The invention concerns an aseptic packaging installation comprising a packaging enclosure (4) containing a line of packaging machines arranged on a floor (8) forming one of the walls of the packaging enclosure (4), a filtering member (17) being connected to the packaging enclosure (4) to generate therein an excess pressure, and a control chamber (3) having a common wall with the packaging enclosure (4), said common wall (2) being open-worked to enable a filtered air stream to be produced from the packaging enclosure (4) towards the control chamber (3).
Patent ES-2230190-T3 (ES)
Inventor: GANSTER OTTO DR
IPC: C08G18/70
Filed: 2001-03-05
Granted: 2005-05-01
Abstract: An aqueous dispersion of isocyanate reactive polymers containing di- and/or polyisocyanate of melting- and/or softening temperature greater than 30 degrees C as a finely divided powder of mean particle diameter less than 100 micron, preferably less than 50 micron is new.   An Independent claim is included for preparation of an adhesive composition in which the above dispersion is applied to the substrate to be adhesive bonded, the assembly is dried, the dried adhesive coating is decrystallized by heating for a short time at less than 110 degrees C, preferably less than 90 degrees C, and is joined to the substrate in the decrystallized state.
Patent ES-2240329-T3 (ES)
Inventor: PASINI GIOVANNI BATTISTA
IPC: D01G15/20
Filed: 2001-11-13
Granted: 2005-10-16
Abstract: A flat card fed with fibres (4A,4B) by means of a plurality of feed devices (20A,20B) comprising licker-in rollers (8A,8B) that operate in parallel so as to feed different fibres onto different points of the main carding drum (10), where the feed points are set sequentially and are staggered in such a way as to constitute, on the main carding drum, a series of pre-carding areas that are specific for the fibres fed at each point and that are provided with equipment adjustable for each type of fibre that is being processed. <IMAGE>
Patent ES-2215107-T3 (ES)
Inventor: CATTANEO CARLO
IPC: A47B13/02
Filed: 2001-11-19
Granted: 2004-10-01
Abstract: An expander for table legs consists of two elements, internal and external, joined to each other in a coaxial position by a threaded unit, wherein the internal element is a truncated cone body (12), having an external lateral surface (20) in the form of a truncated cone, sloping at an angle ( alpha ) with respect to the vertical, and equipped with a threaded hole (14), and wherein the external element, elastically deformable, consists of an accordion wall (13) with a radial sectored structure, in which sectors (24) form an external cylindrical contact surface (26), which interacts with an internal surface of a hollow tubular leg (34) and in which sectors (25) form an internal truncated cone contact surface (27) sloping at an angle ( alpha ), the angle ( alpha ) belonging to a inclination range which is such as to optimize the distribution of acting forces in the expander (10) during tightening. <IMAGE>
Patent ES-2298191-T3 (ES)
Inventor: AHRENS-FATH ISABELLE
IPC: C12Q1/6886
Filed: 2001-10-26
Granted: 2008-05-16
Abstract: Nucleic acid (I) that encodes an androgen receptor variant has a 1329 bp or 1171 bp sequence fully defined in the specification or its equivalents or a sequence that hybridizes to them under stringent conditions. Independent claims are also included for the following: (1) polypeptide (II) encoded by (I); (2) the peptides Asn-Cys-Glu-Arg-Ala-Ala-Ser-Val-His-Phe and Met-Ile-Leu-Trp-Leu-His-Ser; (3) antibody (Ab) specific for (II); (4) vector containing at least one copy of (I); (5) cells transfected with (I) or the vector of (4); and (6) test system for detecting effectors (III) of (II).
Patent ES-2286076-T3 (ES)
Inventor: KURAL CEM
IPC: D06F58/26
Filed: 2001-12-06
Granted: 2007-12-01
Abstract: A household appliance ( 1 ) e.g a washer-dryer, comprises an enclosure ( 2 ) into which objects to be heated are placed, a magnetron ( 4 ) for generating microwaves, a waveguide ( 3 ) for feeding the generated microwave into the enclosure, an arc detector ( 5 ) coupled to the waveguide ( 3 ) for detecting the arcing within the enclosure ( 2 ) and a control unit ( 6 ).
Patent ES-2228809-T3 (ES)
Inventor: MIE PATRICK
IPC: B65D1/00
Filed: 2001-01-23
Granted: 2005-04-16
Abstract: A device for injecting a product towards a predetermined site of objects continuously moving along a given path while being spaced apart from one another by a specific step. The device (10) includes a series of injectors (26) borne by a mobile support (28) while being spaced apart on the support by a pitch corresponding to that of the objects, and the support (28) is driven in a reciprocating movement such that, during a forward phase of the movement, the injectors (26) move each opposite the predetermined site of one of the objects, and in the time interval of the reciprocating movement of the support is equal to the time interval between the passage of two consecutive objects in front of a common fixed point, multiplied by the number of injectors on the support.
Patent ES-2343105-T3 (ES)
Inventor: SHERMAN MERRY R
IPC: A61K38/00
Filed: 2001-02-07
Granted: 2010-07-23
Abstract: A naturally occurring or recombinant protein, especially a mutein of porcine urate oxidase (uricase), that is essentially free of large aggregates can be rendered substantially non-immunogenic by conjugation with a sufficiently small number of strands of polymer such that the bioactivity of the protein is essentially retained in the conjugate. Such conjugates are unusually well suited for treatment of chronic conditions because they are less likely to induce the formation of antibodies and/or accelerated clearance than are similar conjugates prepared from protein preparations containing traces of large aggregates.
Patent ES-2272476-T3 (ES)
Inventor: MAENZ DAVID D
IPC: A23L11/30
Filed: 2001-05-14
Granted: 2007-05-01
Abstract: The present invention relates to a process for the aqueous extraction, fractionation and enzymatic treatment of oilseed materials to generate valued products with no significant low value by-product or waste streams. In particular, the fractionation scheme generates a protein-fiber feed ingredient principally for use with ruminant animals and a second dephytinized high protein fraction. The dephytinized high protein fraction has value as feed ingredient for a variety of species of animals.
Patent ES-2253408-T3 (ES)
Title: Adhesivos de contacto de uso medico dos fases a base de poliacrilatos y sales de poliamina.
Inventor: KOCH ANDREAS
IPC: A61F13/02
Filed: 2001-07-11
Granted: 2006-06-01
Abstract: Adhesivo de contacto de uso médico a base de poliacrilatos y sales de poliamina neutras, caracterizado por presentar una matriz adhesiva de dos componentes poliméricos A y B, en donde - el componente polimérico A es un adhesivo de contacto de poliacrilato que contiene grupos carboxilo, los cuales están neutralizados, - el componente polimérico B es una sal de poliamina neutra, obtenida por reacción de un copolímero de poliacrilato que contiene grupos amina con un ácido, y en donde - el componente polimérico B está disperso en el componente polimérico A, formando ambos componentes un sistema difásico.
Patent ES-2315302-T3 (ES)
Title: Ensayo de capilaridad y procedimientos relacionados.
Inventor: FULWYLER MACK J
IPC: G01N33/558
Filed: 2001-08-17
Granted: 2009-04-01
Abstract: Un método para detectar la presencia de un primer analito diana en una muestra, comprendiendo dicho método: (a) Proporcionar: un sustrato; un canal en una superficie de dicho sustrato; un elemento de cobertura que se superpone y sella dicho canal, teniendo dicho elemento de cobertura una primera superficie de cara a la luz del canal; y una primera pareja de unión para dicho primer analito diana fijado a dicha primera superficie; (b) transportar dicha muestra a través de dicho canal a dicha primera pareja de unión de tal forma que el primer analito diana presente en dicha muestra se une a dicha primera pareja de unión; (c) transportar dicha muestra más allá de dicha primera pareja de unión; y (d) detectar la presencia de cualquier primer analito diana unido a dicha primera pareja de unión, donde dicho elemento de cobertura se desprende de dicho canal para permitir la detección de la presencia de cualquier primer analito diana unido a dicho primer elemento de unión.
Patent ES-2269539-T3 (ES)
Inventor: MENK WERNER
IPC: C22C37/04
Filed: 2002-03-19
Granted: 2007-04-01
Abstract: Spheroidal graphite iron contains C, Si, Mn, Cu, Mg and S as non-ferrous component; and one or more elements selected from group IIIb elements as addition. An Independent claim is also included for a process for the production of a cast iron product from the spheroidal graphite iron. Preferred Features: The Si content is 2.6-2.9 %. The alloy contains 2-200 ppm B as addition.
Patent ES-2368209-T3 (ES)
Inventor: WEITKAMP ROLAND
IPC: F03D1/06
Filed: 2002-08-20
Granted: 2011-11-15
Abstract: Between the blade (6) and the rotor hub a tubular section (8) is fitted. At the upper end the section is linked to the blade by a roller bearing (18) the inner ring (19) of which engages with a motor (21) driven pinion (20). This arrangement is duplicated and the motors are controlled to adjust the blade angle in unison. The power for operating the motors can be electrical, hydraulic or mechanical ( using the rotational energy of the rotor.