baber/WOPTO huggingface dataset:
Patent CA-2249997-A1 (CA)
Title: Chemokine alpha 2
Inventor: SU JEFFREY Y
IPC: C12N5/10
Filed: 1997-03-19
Abstract: Human chemokine Alpha-2 polypeptides and DNA (RNA) encoding such chemotactic cytokines and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemotactic cytokines for the treatment of leukemia, tumors, chronic infections, autoimmune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemotactic cytokines and their use as a therapeutic to treat rheumatoid arthritis, autoimmune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the chemotactic cytokines and for detecting altered levels of the polypeptides in a host.
Patent CA-2250738-A1 (CA)
Inventor: SHEN YOU-TANG
IPC: A61B5/0215
Filed: 1997-03-31
Abstract: A method of simulating congestive heart failure uses catheters (aortic, right at rial, and left atrial), hydraulic occluders (#1, #2), and pacemaker probes (RV, LA) attached to an animal's heart (not numbered) to simula te a chronic condition. A pressure gauge (LV) and flow probe sensor (aortic) are also attached to the heart to monitor the effects of a test compound on the animal's cardiac function and systemic vascular dynamics. A method for assessing the effects of this test compound is i ncluded.
Patent CA-2251112-A1 (CA)
Title: Progressive cavity pumps using composite materials
Inventor: WOOD STEVEN M
IPC: F03C2/08
Filed: 1997-04-24
Abstract: The stator, rotor and/or flex shaft of a progressive cavity pump is made up of composite materials, e.g., fiberglass and resin, in a variety of combinations with and without bonded resilient elastomers. The composites are formulated to provide resiliency and non-resiliency where needed. The flex shaft between the rotary power source and the rotor is made of composite materials and designed to absorb the orbital and gyrational movement of the rotor.
Patent CA-2252093-A1 (CA)
Inventor: PAGANO GAETANO
IPC: A61B6/06
Filed: 1998-10-27
Abstract: An apparatus for radiological examination is provided with the grid 16 that is driven in reciprocating motion in order to reduce the effect of radiation scattered by the body of the patient being irradiated. The grid 16 is connected to a counterweight 23, and is moved through a motion transmission mechanism that is of the crank and connecting-rod type so as to ensure a dynamic balancing of the oscillating masses. With this simple and accurate type of driving system, better quality radiographic images can be obtained under different adjustment and set-up conditions of the apparatus.
Patent CA-2253315-A1 (CA)
Inventor: STEVENS JOHN H
IPC: A61F2/24
Filed: 1997-06-17
Abstract: A multi-lumen catheter (10) having a reinforcing member (42) wrapped around at least one of the lumens (40) in a helical manner. An inflation lumen (43) is positioned outside the reinforcing member (42) for inflating a balloon (11) carried by the catheter (10). A two-lumen extrusion (339A) is bonded to the reinforced lumen (337A) to form the multi-lumen catheter. The multi-lumen catheter is particularly useful as an aortic occlusion catheter.
Patent CA-2254757-A1 (CA)
Title: 1-(1h-pyrrol-2-ylmethyl)-2-piperidone as cell migration inhibitor
Inventor: GEERTS HUGO ALFONS GABRIEL
IPC: A61K31/00
Filed: 1997-05-26
Abstract: The present invention is concerned with the compound 1-(1<u>H</u>-pyrrol-2-ylmethyl)-2-piperidone for use as a medicine, in particular for use as an agent for reducing excessive directional cell migration (as in metastasis);  and with pharmaceutical compositions comprising a pharmaceutically acceptable carrier and the title compound as an active ingredient.
Patent CA-2255210-A1 (CA)
Inventor: VIEGENER FRANCISCO ENRIQUE
IPC: F16K3/08
Filed: 1998-12-04
Abstract: An improved replaceable ceramic disc valve for controlling a fluid flow from a fluid supply, the valve comprising a valve cylindrical cartridge having an axial bore extending between a top open end and a bottom open end of the valve body, the bottom end is connected to the fluid supply when the cartridge is connected to the fluid supply, a rotatable spindle being mounted within the bore and sealed against the bore, the spindle having an upper end, extending outside the valve body and passing through the top open end of the body, and a bottom end, located within the bore, a stationary and a movable ceramic discs being arranged within the bore, the movable ceramic disc being connected to the spindle for regulating the fluid flow through the valve upon rotation of the movable disc relative to the stationary disc, an end socket firmly removably fixed to the bottom open end of the valve body, the socket defining a fluid inlet in fluid communication with the bore in the valve body, and a sealing and urging O-ring being located in an inner part of the socket, around said inlet, for urging the discs to be in contact to each other.
Patent CA-2257095-A1 (CA)
Title: Process for purifying sterically hindered 4-amino piperidines
Inventor: SIEGEL HARDO
IPC: C07D221/20
Filed: 1997-05-30
Abstract: A process for purifying raw piperidines of formula (I), where R1 to R4 are C1 to C6 alkyl, R1 and R2 and/or R3 and R4 together are a CH2 chain with 2 to 5 C  atoms. Said process is characterized in that in an initial step high-boiling-point substances and possible water are eliminated by distillation from the raw piperidines, in a second step 0.01 to 5 wt %, in relation to the product of the first step, of a reducing agent are added and in a third step the piperidines are isolated by distillation.
Patent CA-2260854-A1 (CA)
Inventor: BAENTELI ROLF
IPC: A61K31/70
Filed: 1997-08-06
Abstract: Derivatives of sialyl-Lewis X and A, in which the natural neuraminic acid residue and the natural N-acetylglucosamine monomer are replaced.
Patent CA-2261884-A1 (CA)
Inventor: AMADEI ROBERTO
IPC: C10L1/06
Filed: 1997-07-21
Abstract: The present invention refers to a process for the production of high-octane and low benzene content gasolines according to a cycle where a crude oil is fed into an atmospheric distillation unit from which a fraction is obtained called virgin naphtha sent in turn to a splitting unit that produces a fraction called light tops and a fraction called heavy naphtha wherein said heavy naphtha fraction has a six carbon atoms (C6) hydrocarbons content no greater than 0.5 % volume, and said light tops fraction has a seven plus carbon atoms (C7+) hydrocarbons content no greater than 4 % volume. Said process allows in the refinery to contextually obtain quantitative and qualitative improvements in the gasolines production, with increase of the production yield and of the octane number as well as reduction of the produced benzene quantity.
Patent CA-2262762-A1 (CA)
Inventor: JOHNSON WILLIAM B
IPC: B23C5/20
Filed: 1997-07-30
Abstract: The cutting inserts (52) are provided with positive cutting geometry and are especially adapted for service in face milling and shoulder milling raw castings and other hard-shelled workpieces (45) by providing a cutting edge land (64) which varies in width along the cut from narrowest at the bottom of the main cutting edge (60) to broadest where the cutting edge (60) meets the hard surface of the workpiece (45). In double-ended cutting edges, i.e., where the cutting edge is designed to cut equally in cutters of either hand of rotation, the maximum land width is at the cutting edge midpoint and tapers to minimum width at each end.
Patent CA-2263310-A1 (CA)
Title: In vitro assay for carcinogens using phenotypic transformation of human cells
Inventor: KOWALSKI LINDA A
IPC: C12Q1/02
Filed: 1997-07-31
Abstract: Disclosed is a method to evaluate the carcinogenicity of a compound using a transformation assay. The method includes contacting a compound to be tested for carcinogenicity with a test cell. The test cell has a defect in a protective cellular mechanism selected from the group of a defect in a DNA  damage repair mechanism, a defect in cell cycle control, and a defect in the ability to prevent damage induced by oxygen free radicals. Cell growth is scored to identify the presence or absence of a transformation characteristic.  The development of such a transformation characteristic indicates that the compound being tested is carcinogenic. Further embodiments include a method to identify tissue-specific carcinogens, a method to identify the biochemical mechanism of carcinogenicity of a compound, and a method to evaluate the anticarcinogenicity of a compound.
Patent CA-2264622-A1 (CA)
Title: System and method for dynamic selection of appropriate postal rates based on metering data
Inventor: PIERCE PERRY A
IPC: G06Q20/00
Filed: 1998-06-12
Abstract: A system (10, 20, 30) and method for selecting appropriate postal rates (110, 115, 120) when evidencing postage payment provides new postal rates to a computer (20) responsible for rating mail and provides a date when the new postal rates (110, 115, 120) become effective. The new postal rates (110, 115, 120) and the effective date are stored in the computer (20). When postage evidencing occurs, a selection (215, 220, 225, 230, 240) is made between the current postal rates stored in the computer (20) and the new postal rates for use in evidencing postage payment on a mail piece. The selection is based on the date the mail piece will be submitted for mailing (205, 225, 230, 240).
Patent CA-2265096-A1 (CA)
Inventor: THOMAS JOHN PATRICK
IPC: B29D23/24
Filed: 1999-03-08
Abstract: The present invention relates to a composite flexible hose, preferably for use in automotive air conditioning systems, with improved thermal resistance. The hose consists of an innermost core layer, a friction rubber layer, an intermediate reinforcement layer, and an external cover layer. The innermost layer is a non-plasticized polyamide mixed with a minor portion of polyolefin corresponding to the main rubber constituent of the friction coat layer. The friction coating is formed of a rubber composite of two EPDM rubbers at a weight ratio of 50/50 and 75 parts by weight of carbon black. The intermediate fibrous reinforcement layer is formed of aramid. The external layer is an acrylate rubber comprising a blend of two ethylene acrylates at a weight ratio of 50/50 and 80 parts by weight of carbon black.
Patent CA-2266385-A1 (CA)
Inventor: PLEE DOMINIQUE
IPC: B01J20/18
Filed: 1998-07-10
Abstract: The invention concerns a method for obtaining agglomerates of faujasite X comprising at least 95 % of faujasite LSX, i.e. with Si/Al ratio equal to 1, constituting the active adsorbent. The agglomerate is formed from LSX zeolite and a binder capable of zeolitization the transformation of which into active zeolite is obtained by zeolitization in a sodium/potassium or sodium liquor.
Patent CA-2267817-A1 (CA)
Title: End pumped zig-zag slab laser gain medium
Inventor: HOEFER CAROLYN S
IPC: H01S3/16
Filed: 1999-03-31
Abstract: An optical amplifier which includes an elongated slab of solid state lasing material, such as a rare earth doped yttrium-aluminum-garnet (YAG). In order to provide a relatively increased absorption length and thus a higher overall efficiency, the optical amplifier in accordance with the present invention incorporates end pumping in which the pumped light is coaligned with the amplified light resulting in relatively longer absorption lengths and higher overall efficiencies. The coaligned pumped sources are directed to lateral faces of the slab which include windows, formed from an insulating coating such as an anti-reflection coating, at the pump wavelength. In order to cause internal reflection of the pump beam along the lasing axis, the end faces are formed at about a 45° angle relative to the longitudinal axis which causes the pumped light to be reflected within the slab co-axially with a amplified light. In order to confine the absorption of the pumped light to the center portion of the slab, the opposing end portions of the slab may be undoped while the center portion of the slab along the longitudinal axis is doped. Such a configuration provides relatively low residual thermal lensing with virtually no birefringence.
Patent CA-2269983-A1 (CA)
Inventor: MIKHAIL W E MICHAEL
IPC: A61F2/46
Filed: 1997-11-20
Abstract: Une méthode et un dispositif permettant de réaliser une intervention sur la hanche utilisent un manchon (30) préformé constitué d'un matériau ciment osseux et comportant des orifices (33), que l'on positionne dans la cavité fémorale. On injecte du ciment osseux frais sous pression de façon à remplir la cavité fémorale, y compris les orifices (33) et tous les espaces ou vides entre le manchon préformé et la paroi de la cavité. On implante à l'intérieur de celle-ci une prothèse (24) fémorale comportant une partie tige. La paroi interne du manchon (30) est plus large que la partie de la paroi externe de la tige (24) encerclée par le manchon (30), de façon qu'il y ait du ciment osseux frais entre la paroi interne du manchon (35) et la tige (24).
Patent CA-2273249-A1 (CA)
Title: Method of preventing corrosion of metals using silanes
Inventor: VAN OOIJ WIM J
IPC: C09D183/04
Filed: 1998-01-08
Abstract: A method of preventing corrosion of metals using silanes. The method comprises applying a first treatment solution directly onto the surface of the metal, wherein the first treatment solution contains at least one multi-functional silane having at least two trisubstituted silyl groups, and wherein the substituents are individually chosen from the group consisting of alkoxy and acetoxy. An optional second treatment solution containing an organofunctional silane may also be employed, particularly if the metal is to be painted.
Patent CA-2274532-A1 (CA)
Inventor: MUENCH ROBERT
IPC: G06F1/04
Filed: 1997-12-09
Abstract: The invention relates to a unit which is controlled by a logical load unit (PLU), and which can be configured or reconfigured during running time, according to the following configuration: the invention provides for a programmable arithmetic logic unit (EALU), whose function and network connection are programmed in registers in which a plurality of data can be processed without reprogramming of the processing elements (PAE). To control the arithmetic logic unit (EALU), the invention provides for a state machine (SM-UNIT); it further provides registers for each operand (O-REG) and the result (R-REG), which are designed in part to act as shift registers. Feedback of the data of the results register takes place via a multiplexer (R20-MUX) to one of the inputs of the EALU. A bus multiplexing unit (BM-UNIT) makes it possible for the data to be taken from a bus system or for the result to be fed into a bus system, whereby the bus unit can send data to several receivers and synchronisation, even of several receivers, takes place automatically. The registers prevent the data processing system in the EALU to have access to the bus, so that each PAE can be considered an independent unit in that the configuration or reconfiguration of a PAE does not disturb the data originators and receivers or the independent PAEs.
Patent CA-2276524-A1 (CA)
Title: Antenna beam patterns having wide nulls
Inventor: WANG SHAY-PING THOMAS
IPC: H04B7/204
Filed: 1998-11-03
Abstract: An enhanced digital beamformer (EDBF) (210, FIG. 2) is provided for use in a transceiver subsystem (200, FIG. 2) for mitigating interference and increasing the frequency reuse factor in communication systems.  Ile EDBF is used to produce wide nulls (520, FIG. 5) in at least one steerable antenna beam pattern. By directing wide nulls at undesired signals, the EDBF provides a more efficient processing of antenna beam patterns in communication systems. The EDBF is used in geostationary satellites, non-geostationary satellites, and terrestrial communication devices. The EDBF combines a unique algorithm, a special processor, and an array antenna to significantly improve the capacity of current and future communication systems, while remaining compatible with existing modulation techniques.
Patent CA-2279819-A1 (CA)
Inventor: HONG KYUNG-SOO
IPC: A41D25/00
Filed: 1999-08-10
Abstract: This invention relates to a necktie of which a small width portion and a large width portion are unable to be released from each other by a loop positioned in the rear of a large width portion as well as the remainder hung down therefrom after rounding the girth of a shirt collar is fixed by buttons in the shirt, constructed in that the cloth piece 50 with buttonholes 52 in which the button 44 positioned at the front center of the shirt 40 can be fasten is attached to the rear of the small width portion 32 of the necktie 30 or that the buttonholes 90 in which the button 84 positioned at the front center of the shirt 80 are formed directly in the rear of the small width portion 72 or the large width portion 140 of the necktie 70.
Patent CA-2280587-A1 (CA)
Title: Growth hormone secretagogues
Inventor: CARPINO PHILIP ALBERT
IPC: A61K31/4985
Filed: 1999-08-19
Abstract: This invention is directed to compounds of the formula   and the pharmaceutically-acceptable salts thereof, where the substituents are as defined in the specification, which are growth hormone secretogogues and which increase the level of endogenous growth hormone. The compounds of this invention are useful for the treatment and prevention of osteoporosis, congestive heart failure, frailty associated with aging, obesity; accelerating bone fracture repair, attenuating protein catabolic response after a major operation, reducing cachexia and protein loss due to chronic illness, accelerating wound healing, or accelerating the recovery of burn patients or patients having undergone major surgery; improving muscle strength, mobility, maintanence of skin thickness, metabolic homeostasis or renal homeostasis. The compounds of the present invention are also useful in treating osteoporosis when used in combination with: a bisphosphonate compound such as alendronate; estrogen, premarin, and optionally progesterone; a (33 adrenergic receptor agonist; an estrogen agonist or antagonist; or calcitonin, and pharmaceutical compositions useful therefor. Further, the present invention is directed to pharmaceutical compositions useful for increasing the endogenous production or release of growth hormone in a human or other animal which comprises an effective amount of a compound of the present invention and a growth hormone secretagogue selected from GHRP-6, Hexarelin, GHRP-1, growth hormone releasing factor (GRF), IGF-1, IGF-2 or B-HT920.
Patent CA-2282578-A1 (CA)
Title: Coagulation precipitator
Inventor: MIYANOSHITA TOMOAKI
IPC: C02F1/52
Filed: 1998-12-25
Abstract: A coagulation precipitator having a coagulation precipitation section provided with a contact material-accumulated layer (84) formed by accumulating small pieces of a contact material of a high prosity, raw water to which a coagulant is added being supplied upstream to the coagulation precipitation section to coagulate the suspension in the raw water and precipitate the coagulated suspension, wherein the coagulation precipitator is provided with a prestage coagulation section as a pretreatment section having at least one contact material-accumulated layer (82) through which the raw water is passed at a superficial velocity higher than that in the contact material-accumulated layer in the coagulation precipitation section, primarily treated water being discharged from the prestage coagulation section with the coagulated flock produced in the contact material-accumulated layer, to be supplied into the coagulation precipitation section, whereby a frequency at which to carry out a cleaning operation can be reduced while the treated water is maintained at a low turbidity.
Patent CA-2286121-A1 (CA)
Title: Food grade wax and process for preparing same
Inventor: VALIX MARJORIE GAN
IPC: A23P20/10
Filed: 1998-04-07
Abstract: The invention provides a wax composition which can be used in comestibles. The wax composition is obtained from sugar cane and comrpises wax esters, aldehydes, tri-glycerides, alcohols, free fatty acids, sterols and polar lipids. A process for preparing a wax composition from crude sugar cane wax, the process comprising the steps of: (i) heating a solution of the crude wax with a lower alcohol as sovlent at the boiling point of the solvent; (ii) allowing phase separation of the solution from (i) and decanting the upper phase while hot; (iii) allowing the separated phase from (ii) to cool and separating crystallised wax from the solvent; (iv) repeating steps (i) to (iii) using the wax from (iii) until all pitch has been removed fromthe wax; (v) heating the wax to between 90 and 140 ~C and oxidising molten wax with oxidising material; and (vi) continuing the heating under and inert gas on completion of the oxidation step until intermediate peroxide products are removed.
Patent CA-2288392-A1 (CA)
Inventor: ALLEN DENISE ANN
IPC: B65D5/54
Filed: 1999-10-29
Abstract: A display package including an outer container and one or more inner containers housed in the outer container. The outer container is made from a transparent material which is selectively coated to provide both opaque and translucent areas on the surface of the outer container while leaving some transparent areas. The opaque and translucent areas may be used to display indicia about the product whereas the transparent areas provide a view of the inner containers and/or any indicia thereon. A variety of visual effects can be achieved by selecting the appropriate colors and/or transitions between the opaque, translucent and transparent areas of the outer container.
Patent CA-2291529-A1 (CA)
Title: Flexible face sign
Inventor: DUGUAY ELOI
IPC: G09F13/04
Filed: 1999-12-03
Abstract: A flexible face material sign framing system allows the interior portion of the sign casing to be accessed without removing the face material from the framing. The system includes a device for grasping the flexible face material and exerting tension to its edges in order to tighten the front of the sign appropriately. The system and device are weatherproof and therefore prolong the life of the face material.
Patent CA-2292136-A1 (CA)
Title: Lamp with a mechanical base
Inventor: MUEHLICH ERNST
IPC: H01R33/09
Filed: 1999-12-08
Abstract: A lamp bulb (1) made from glass is sealed at one end by a pinch (2). A base (5) is fastened on the pinch (2) by means of a metal spring (6). The base (5) has a holder (7) loosely adapted to the pinch (2). The metal spring (6; 26) is bent in a U-shaped fashion and comprises a base part (11) and two limbs (12, 13) which embrace the pinch, the fastening of the base (5) being accomplished by virtue of the fact that one limb (12) is aligned essentially parallel to the longitudinal axis, but simultaneously has a transverse extent accessible to spring forces, the transverse extent of this limb being stressed by the holder (7) of the base.
Patent CA-2292856-A1 (CA)
Title: Electronic driving circuit for a bistable actuator
Inventor: COLOMBO FRANCO
IPC: H02H3/33
Filed: 1999-12-21
Abstract: An electronic driving circuit for a bistable actuator activated by piezoelectric elements, particularly for residual-current devices, the circuit comprising voltage step- up means which are suitable to step up and store a voltage generated across a secondary winding of a current sensor, the step-up means being connected to threshold setting means which are suitable to determine an intervention threshold of a bistable actuator activated by piezoelectric elements, whose activation is determined by an excitation voltage applied across it which is higher than the voltage threshold set by the threshold setting means.