baber/WOPTO huggingface dataset:
Patent AU-2016359235-A1 (AU)
Title: Antibody-drug conjugates comprising branched linkers and methods related thereto
Inventor: OH YEONG SOO
IPC: A61K47/06
Filed: 2016-11-23
Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody.
Patent AU-2016362495-A1 (AU)
Title: Seneca valley virus (SVV) cellular receptor targeted oncotherapy
Inventor: MILES LINDE
IPC: G01N33/53
Filed: 2016-12-02
Abstract: A method for selecting cancer patient for treatment with Seneca Valley Virus (SVV) by determining expression of ANTXR1 in a cancerous tissue in a cancer patient; and designating the cancer patient as a candidate for treatment with SVV if normal levels or elevated levels of ANTXR1 expression is detected in the cancerous tissue. Also a method for treating a cancer patient with SVV is disclosed.
Patent AU-2016398923-A1 (AU)
Title: Formulation and method for the prevention and/or treatment of hangover symptoms
Inventor: HOWES LAURENCEE GUY
IPC: A61P25/32
Filed: 2016-03-24
Abstract: A formulation and a method for treating, preventing, ameliorating or alleviating in a patient the symptoms of hangover, or of veisalgia, associated with a bout of excessive alcohol consumption are disclosed. More specifically, a formulation comprising L- cysteine, thiamine and pyridoxine and a method for treating, preventing, ameliorating or alleviating in a patient one or more of the symptoms of nausea, headache, diminished concentration, malaise and/or tiredness, and a desire to consume greasy and/or fatty and/or oily foods, associated with a bout of excessive alcohol consumption are disclosed.
Patent AU-2016418333-A1 (AU)
Title: Backless support bra
Inventor: GEHLHAUSEN GORDANA
IPC: A41C3/00
Filed: 2016-08-08
Abstract: A backless support bra having a front main portion with first and second upper shoulder straps and first and second lower pelvic straps, which are designed to pass through the pelvic region of a wearer, securing the bra in place and providing support to the wearer without exposing bra wings in the back region of the wearer. Various methods of securing the backless support bra are also provided.
Patent WO-2017201566-A1 (WO)
Title: Matériau aéré activé par un alcali
Inventor: VISSER DAVID DIRK
IPC: C04B38/10
Filed: 2017-05-29
Abstract: La présente invention concerne un mélange géopolymère humide comprenant une mousse préformée. La mousse a pour effet d'aérer le mélange avant le durcissement. Le résultat de l'addition de la mousse préformée est un matériau géopolymère aéré qui devient un géopolymère cellulaire léger après durcissement.
Patent WO-2018000039-A1 (WO)
Title: Enregistrement de caméra dans un système multicaméras
Inventor: NOBLE JOHN
IPC: G06T7/70
Filed: 2017-06-29
Abstract: L'invention concerne un procédé (500) consistant à enregistrer la position et l'orientation d'une ou de plusieurs caméras (312315) dans un système d'imagerie par caméra (100, 400). Le procédé comprend : à l'étape (502), la réception, à partir d'un dispositif d'imagerie de profondeur (330), de données indicatrices d'une image tridimensionnelle de la scène. A l'étape (503), l'image tridimensionnelle est étalonnée avec un cadre de référence par rapport à la scène. Le cadre de référence comprend une position de référence et une orientation de référence. A l'étape (504), une position tridimensionnelle de chacune des caméras à l'intérieur de l'image tridimensionnelle est déterminée dans le cadre de référence. A l'étape (505), une orientation de chaque caméra est déterminée dans au moins une dimension dans le cadre de référence. A l'étape (506), la position et l'orientation pour chaque caméra sont combinées pour déterminer une pose de caméra dans le cadre de référence.
Patent AU-2017211331-A1 (AU)
Title: Combination therapy for treating cancer
Inventor: RAIMONDI MARIA ALEJANDRA
IPC: A61K31/444
Filed: 2017-01-27
Abstract: The disclosure relates to a method for treatment of cancer comprising administering to a subject in need thereof a first agent in a therapeutically effective amount and a second agent in a therapeutically effective amount. Preferably, the first agent comprises an EZH2 inhibitor, e.g., tazemetostat or a pharmaceutically acceptable salt thereof. In certain embodiments, the methods of the disclosure are used to treat breast cancer, ovarian cancer, or both.
Patent AU-2017260363-A1 (AU)
Title: Modulators of the integrated stress pathway
Inventor: SIDRAUSKI CARMELA
IPC: C07D413/12
Filed: 2017-05-05
Abstract: Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
Patent AU-2017265072-A1 (AU)
Title: Method of Producing Metal-Coated Steel Strip
Inventor: NEUFELD AARON KIFFER
IPC: C23C2/04
Filed: 2017-11-22
Abstract: A method of forming a coating of an Al-Zn-Si-Mg alloy on a steel strip to form an Al-Zn-Mg-Si coated steel 5 strip is disclosed. The method includes the steps of dipping steel strip into a bath of molten Al-Zn-Si-Mg alloy and forming a coating of the alloy on exposed surfaces of the steel strip and cooling the coated strip with cooling water. The cooling step includes controlling the pH of cooling water 10 to be in a range of pH 5-9. Particular embodiments focus on Al-Zn-Si-Mg alloys that contain the following elements in % by weight: Zn: 30 to 60, Si: 0.3 to 3, Mg: 0.3 to 10, and Balance Al and unavoidable impurities. 6------- 0
Patent AU-2017277916-A1 (AU)
Title: Anti-CD98 antibodies and antibody drug conjugates
Inventor: BENATUIL LORENZO
IPC: A61K47/68
Filed: 2017-06-08
Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
Patent AU-2017287762-A1 (AU)
Title: Pyrazolopyrimidine derivatives as kinase inhibitor
Inventor: KIM IN WOO
IPC: A61K31/496
Filed: 2017-06-30
Abstract: The present invention relates to a pyrazolopyrirmidine derivative, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions.
Patent AU-2017317643-A1 (AU)
Title: Catheter tube
Inventor: POKORNY VIT
IPC: A61M25/01
Filed: 2017-08-30
Abstract: The present invention relates to a catheter, which comprises a catheter tube everting inside-out during the process of catheterization. A catheter tube comprises a plurality of longitudinal protrusions extending from the first end of the catheter tube through at least a portion of the catheter tube, and forming an angle of 0 degrees to 45 degrees with respect to the longitudinal axis of the catheter tube and facing radially inwards, and means for dilating a circumference of the catheter tube upon everting the catheter tube inside-out from the first end of the catheter tube. The longitudinal protrusions ensure the axial reinforcement of the catheter tube, which prevents the tube from collapsing and bending under the axial force and the resistance of the fold and of the friction between the everted portion and the corresponding underlying portion of the tube. The dilating means dilate the circumference of the catheter tube in the everted region, thus reducing the resistance of the fold and of the friction between the everted portion and the corresponding underlying portion of the tube.
Patent AU-2017357527-A1 (AU)
Title: Drying of nanocellulose using ammonia in a supercritical state
Inventor: JENNEKENS MATH
IPC: C08L1/02
Filed: 2017-11-07
Abstract: It is an object of the present invention to provide a process for producing non-surface modified nanocellulose particles, in particular in the form of a powder, comprising the steps of i. providing a suspension of never-dried, non-surface modified nanocellulose particles in an aqueous liquid, which aqueous liquid is non-solubilising for the non-surface modified nanocellulose particles, and which aqueous liquid is water or an aqueous solution of morpholine or piperidine or mixtures thereof, ii. contacting the suspension of non-surface modified nanocellulose particles with a fiuid in a supercritical state, which fiuid is miscible with the aqueous liquid and is non-solubilising for the non-surface modified nanocellulose particles, under conditions suitable for the transfer of the aqueous liquid into the fluid in a supercritical state, iii. removing the aqueous liquid and the fluid in a supercritical state, preferably by controlling pressure and/or temperature, to form the non-surface modified nanocellulose particles, iv. collecting the non-surface modified nanocellulose particles, characterized in that the fluid in a supercritical state comprises, or consists of, ammonia (NH3) in a supercritical state.
Patent AU-2017359293-A1 (AU)
Title: System for integrally measuring clinical parameters of visual function
Inventor: GARCÍA RAMOS EVA
IPC: A61B3/08
Filed: 2017-10-27
Abstract: System for integrally measuring clinical parameters of visual function, including: a display unit (20) for representing a scene with a 3D object having variable characteristics, such as the virtual position and virtual volume of the 3D object within the scene; movement sensors (60) for detecting the position of the user's head and distance from the display unit (20); tracking sensors (10) for detecting the position of the user's pupils and pupillary distance; an interface (30) for interaction between the user and the scene; and processing means (42, 44) for analysing the user response, based on the data from the sensors (60, 10) and the interface (30), with the variation in the characteristics of the 3D object, and based on the estimation of a plurality of clinical parameters of visual function related to binocularity, accommodation, ocular motility and visual perception.
Patent AU-2017365173-A1 (AU)
Title: Fungicidal compounds and mixtures for fungal control in cereals
Inventor: BIRO AKOS
IPC: A01N43/40
Filed: 2017-11-22
Abstract: A fungicidal composition containing a fungicidally effective amount of the compound of Formula I, 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-1-y1)propyl)pyridin-3-yl)oxy)benzonitrile for use on fungal diseases of cereals. Additionally, this disclosure concerns a fungicidal composition containing (a) the compound of Formula I, 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-1-y1)propyl)pyridin-3-yl)oxy)benzonitrile and (b) the compound of Formula II, (
Patent AU-2017371488-A1 (AU)
Title: Peptide modulator of purinoceptors
Inventor: VASSILEVSKI ALEXANDER ALEXANDROVICH
IPC: A61P29/00
Filed: 2017-05-31
Abstract: The invention relates to medicine and pharmacology, specifically to biologically active peptides that modulate purinergic signaLling. To this end, a peptide is proposed that has the following amino acid sequence: Gly
Patent AU-2017375828-A1 (AU)
Title: Cytoplasmic transduction peptide and intracellular messenger comprising same
Inventor: BAEK YI YONG
IPC: C07K14/005
Filed: 2017-12-15
Abstract: The present invention relates to a cytoplasmic transduction peptide and an intracellular messenger comprising the same. Compared with a virus-derived cytoplasmic transduction peptide, the intracellular messenger of the present invention has an advantage of enabling a substance to be effectively delivered into cells even at a low concentration.
Patent AU-2017441973-A1 (AU)
Title: Ultrasonic scalpel bit, ultrasonic vibration propagation assembly and ultrasonic hemostasis and cutting system
Inventor: CAO QUN
IPC: A61B18/04
Filed: 2017-12-07
Abstract: Disclosed is an ultrasonic hemostasis and cutting system, comprising an ultrasonic vibration propagation assembly. An ultrasonic scalpel head (101) in the ultrasonic vibration propagation assembly comprises an ultrasonic scalpel tip (11), a connecting part (13), vibration node bosses (14) and a waveguide (15), wherein the ultrasonic scalpel tip (11) is arranged in front of the waveguide (15), the connecting part (13) is arranged behind the waveguide (15), the vibration node bosses (14) are arranged on the waveguide (15), the ultrasonic scalpel tip (11) is laterally bent at a tip thereof, and a vibration guide groove (12) is further provided in the ultrasonic scalpel head (101). By designing the ultrasonic scalpel head as a bent shape and converting longitudinal ultrasonic vibration into longitudinal and torsional compound vibration, temperature uniformity inside a cut or coagulating tissue can be improved, thus the efficiency and safety of hemostasis and cutting are improved.
Patent AU-2017442099-A1 (AU)
Title: Decontamination compositions and methods of decontamination
Inventor: LALGUDI RAMANATHAN S
IPC: A62D3/38
Filed: 2017-12-05
Abstract: Decontamination compositions are described. The decontamination composition comprises an aqueous solution of a water soluble cerium salt or a dispersion of cerium oxide in water. The decontamination composition may optionally include at least one of an oxidizer, a surfactant, a co-solvent, a chelating agent, and a polymer. Methods of decontaminating clothing are also described.
Patent AU-2018200111-A1 (AU)
Title: Optimised subcutaneous therapeutic agents
Inventor: HENRY WILLIAM
IPC: A61P7/04
Filed: 2018-01-05
Abstract: Methods and dosage formulations are provided for subcutaneous administration in which therapeutic agents are modified to increase the hydrophilicity and molecular dimensions in relation to the native state of the therapeutic agent, in which the Cmax:Caverage ratio is lower than the Cmax:Caverage ratio of the 5 agent when delivered intravenously. x -- - -- - -- t5 >< ----- ---- U- U U 0 - > ca LLoUL _ U- CL
Patent AU-2018201053-A1 (AU)
Title: Procedure and system for the extraction of isocyanuric acid in solution
Inventor: MACIAS GALLEGO CARLOS
IPC: C02F1/58
Filed: 2018-02-13
Abstract: PROCEDURE AND SYSTEM FOR THE EXTRACTION OF ISOCYANURIC ACID IN SOLUTION A procedure and a system for the extraction of isocyanuric acid are disclosed. According to the invention, the water containing isocyanuric acid is passed through a 10 bed with an adsorbent material, the bed regeneration is carried out by using a liquid regeneration medium, the liquid regeneration medium that contains isocyanuric acid in solution is collected, its recovery is carried out by adding a solid complexing substance, the suspension 15 obtained is passed through a filtering medium and isocyanuric acid is recovered and the liquid extraction medium is regenerated. The system comprises an adsorption column, a deposit of regenerating substance, a filtering medium, a dosage tank to dose the regenerating substance, a 20 compressor, a drive pump and a valves system to configure the equipment according to the phase of the cycle in which it has to operate.
Patent AU-2018204167-A1 (AU)
Title: System and Tools for Enhanced 3D Audio Authoring and Rendering
Inventor: ROBINSON CHARLES Q
IPC: H04S3/00
Filed: 2018-06-12
Abstract: The invention is directed to a method, which comprises receiving audio reproduction data comprising one or more audio objects and metadata associated with each of the one or more audio objects; receiving reproduction environment data comprising an indication of a number of reproduction speakers in the reproduction environment and an indication of the location of each reproduction speaker within the reproduction environment; and rendering the audio objects into one or more speaker feed signals by applying an amplitude panning process to each audio object, wherein the amplitude panning process is based, at least in part, on the metadata associated with each audio object and the location of each reproduction speaker within the reproduction environment, and wherein each speaker feed signal corresponds to at least one of the reproduction speakers within the reproduction environment. The metadata associated with each audio object includes audio object coordinates indicating the intended reproduction position of the audio object within the reproduction environment and zone constraint metadata indicating whether rendering the audio object involves imposing speaker zone constraints. UC\ G 0o Q* 0 4- 0 0) L 0 U) 00
Patent AU-2018208491-A1 (AU)
Title: Detection of flow rate over dynamic range
Inventor: LU MINFU
IPC: G01F1/7082
Filed: 2018-01-10
Abstract: Aspects of the disclosure are directed to a obtaining a first plurality of signals associated with a fluid flow in a pipe, processing, by a processor, the first plurality of signals to obtain a first plot of power associated with first vortices in the fluid flow and a flow rate of the fluid flow in the pipe over a first flow rate range, determining, by the processor, that a maximum value of the power in the first plot corresponds to a maximum value of the flow rate included in the first flow rate range or that the power is increasing as a function of the flow rate towards an end of the first plot, and based on said determining, multiplying, by the processor, values of the first flow rate range to obtain a second flow rate range.
Patent AU-2018220034-A1 (AU)
Title: Intelligent automated assistant for media exploration
Inventor: GRAHAM DAVID CHANCE
IPC: G10L21/00
Filed: 2018-04-17
Abstract: Attorney Docket No.: P33955WO1/7870000273503 Systems and processes for operating an intelligent automated assistant are provided. In accordance with one example, a method includes, at an electronic device with one or more processors and memory, receiving a first natural-language speech input indicative of a request for media, where the first natural-language speech input comprises a first search parameter; providing, by a digital assistant, a first media item identified based on the first search parameter. The method further includes, while providing the first media item, receiving a second natural language speech input and determining whether the second input corresponds to a user intent of refining the request for media. The method further includes, in accordance with a determination that the second speech input corresponds to a user intent of refining the request for media: identifying, based on the first parameter and the second speech input, a second media item and providing the second media item.
Patent AU-2018227418-A1 (AU)
Title: Sample tube holder and system and method employing same
Inventor: LYNN DANIEL
IPC: A61B5/15
Filed: 2018-02-27
Abstract: A sample tube holder (40) includes an elongated body (42) with an open end (46) suitable for receiving sample vials. A lid (50) is pivotally attached to body and movable to a position over the open end. The lid includes an aperture (62) that is configured to allow a portion of a vascular access needle assembly to extend through the aperture while an access needle (20) and needle protector (34) portion of the assembly are captured and confined within the body to afford added protection against accidental needle sticks.
Patent AU-2018243123-A1 (AU)
Title: B7-H3 antibody, antigen-binding fragment thereof and medical use thereof
Inventor: GU JINMING
IPC: A61K39/00
Filed: 2018-03-30
Abstract: The invention provides a B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof. Further, the present invention discloses a pharmaceutical composition comprising the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament. In particular, the invention discloses a use of a human B7-H3 human antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition.
Patent AU-2018255320-A1 (AU)
Title: Deployment constraining sheath that enables staged deployment by device section
Inventor: JOHNSON MATTHEW A
IPC: A61B17/00
Filed: 2018-04-18
Abstract: Various aspects of the present disclosure are directed toward medical devices, systems, and methods. The medical devices may include a portion having a radially expansive force greater than a radially expansive force other portions of the device. In addition, the medical device may include one or more constraining mechanisms for deployment of the medical devices.
Patent AU-2018255413-A1 (AU)
Title: K-Ras modulators
Inventor: MCCORMICK FRANK
IPC: C07D307/28
Filed: 2018-04-20
Abstract: Provided herein,
Patent AU-2018256532-A1 (AU)
Title: Monitor and control system for a harvester
Inventor: DIGHTON JOHN A
IPC: A01D41/127
Filed: 2018-10-31
Abstract: James & Wells Ref: 310418AU A harvester including a frame supported by a drive assembly for movement along a support surface, a head unit coupled to the harvester and configured to selectively harvest crop material, a camera coupled to the frame and configured to generate one or more images of a field of view, and a controller in operable communication with the camera and the head unit, where the controller is configured to determine one or more crop attributes based at least in part on the one or more images produced by the camera. C)o C)o C.C> 00 C)o 00-4 \ Z:: OC) r C.C> CZ> ------- LC'> 11 r C-> LL CC> CZ> LC'> cv,> C.C> LC'> CZ> CC> c 2 CZ>
Patent AU-2018335764-A1 (AU)
Title: Inferred bird's-eye view for trailer reverse assist
Inventor: GOMEZ-MENDOZA RODRIGO
IPC: G08G1/16
Filed: 2018-09-21
Abstract: A method of generating an overhead view of a tow vehicle and a trailer attached to the tow vehicle is provided. The method includes receiving first sensor system data from a sensor system and determining a trailer width based on the first sensor system data. The method includes receiving a second sensor system data from the sensor system and determining a trailer length based on the sensor system data. The method includes determining a separation distance between the trailer and the vehicle based on the first and/or second sensor system data. The method includes generating an overhead image including a vehicle representation and a trailer representation based on the trailer width, the trailer length, the separation distance, the vehicle length, and the vehicle width. The method also includes transmitting instructions to display the overhead image.
Patent AU-2018389732-A1 (AU)
Title: Marine surface drone and method for characterising an underwater environment implemented by such a drone
Inventor: CORBIERES CHRISTOPHE
IPC: G01S15/96
Filed: 2018-12-20
Abstract: The invention relates to a marine surface drone (1) comprising: - an on-board multi-beam sonar (10); - a system (41) for controlling the sonar, configured to command, for a given position of the drone, a plurality of consecutive emissions of acoustic waves, the control system controlling the sonar emitters (12) so as to vary the characteristics of the emitted acoustic waves, from one of said emissions to the next, and - an acquisition unit (42) configured to determine, from echo signals acquired in response to said plurality of emissions, a three-dimensional image representing the content of a given observation volume. The invention also relates to a method for characterising an underwater environment, implemented by such a drone. Figure