baber/WOPTO huggingface dataset:
Patent DE-60226881-D1 (DE)
Inventor: HUBSCH ALPHONSE
IPC: A61P9/10
Filed: 2002-08-20
Granted: 2008-07-10
Abstract: The present invention relates to a method for the prophylaxis and/or treatment of stroke and other ischemic injury, wherein HDL is administered to a subject in need thereof, particularly by intravenous infusion.
Patent DE-60228419-D1 (DE)
Inventor: ZE EV RONAI
IPC: A61K31/7088
Filed: 2002-02-14
Granted: 2008-10-02
Abstract: The present invention relates to novel therapies for cancer and, in particular, to therapies that are particularly suited to tumor cells resistant to other types of therapies such as radiation, chemotherapy, or combinations of both approaches. The invention provides methods for identifying and implementing strategies to inhibit a transcription factor which, in combination with other factors, renders the cells resistant and inhibits apopotosis of the cells. The invention provides an inhibitory ATF2 N-terminal fragment, specifically a fragment corresponding to amino acid residues 50-100 of ATF2 (termed peptide II). The invention provides methods for inhibiting tumor cell growth with such peptides.
Patent DE-60235179-D1 (DE)
Inventor: COULAM JOHN PATRICK
IPC: A01D33/04
Filed: 2002-09-26
Granted: 2010-03-11
Abstract: An agricultural separator comprises a first rotatable member 3 and a second rotatable member 4 rotatable about substantially parallel spaced axes. The first rotatable member 3 carries a plurality of wheels 1 with angularly-spaced resilient fingers 2 and the second rotatable member 4 carries a plurality of corresponding cam members 5. Each cam member 5 has at least one cam surface 6 at its periphery and the rotatable members 3,4 are arranged such that, in use, the cam surface 6 on each cam member 5 engages and squeezes at least one of the resilient fingers 2 of the corresponding wheel 1 to facilitate cleaning of the wheels. Cam member 5 may be in the form of a wheel or roller.
Patent DE-60237656-D1 (DE)
Inventor: SHIBUYA YASUHIRO
IPC: B29C48/92
Filed: 2002-02-20
Granted: 2010-10-28
Abstract: A practically applicable plate-like body attached with a resin frame in which a thermoplastic elastomer is used as a resin material for the frame. A molded product 7 of thermoplastic elastomer extruded from a molding die 6 is cooled to 100 DEG C or less; a lip portion of the molded product 7, an attached surface to be attached to the plate-like body 1, of the molded product 7 and a pressed surface of the molded product 7 are heated so that the temperature TL of the lip portion, the temperature TA of the attached surface and the temperature TO of the pressed surface have relations of TO<TL<TA and TA>/=200 DEG C, and then, the pressed surface is pushed whereby the molded product 7 is firmly attached to an outer peripheral portion of the plate-like body 1 by the aid of the attached surface. <IMAGE>
Patent DE-60237983-D1 (DE)
Inventor: HONJO TASUKU
IPC: C07K14/47
Filed: 2002-10-22
Granted: 2010-11-25
Abstract: The present invention relates to human, rat and mouse stem cell-derived neuron survival factor polypeptides (SDNSF), a process for producing them, cDNA encoding SDNSF, a vector comprising the cDNA, host cells transformed by the vector, an antibody against SDNSF, pharmaceutical compositions containing SDNSF or the antibody, a method of assaying SDNSF, a reagent for assaying SDNSF, and a screening method using SDNSF. The polypeptides are effective in the survival of nerve cells and, therefore, efficacious in treating injury to the central nerve system caused by brain infarction, brain hemorrhage, spinal cord injury, etc.
Patent DE-60239598-D1 (DE)
Inventor: FIERE VINCENT
IPC: A61B17/80
Filed: 2002-04-03
Granted: 2011-05-12
Abstract: The invention concerns a stabilized interbody fusion system for vertebrae, of the type comprising an interbody implant ( 4 ) designed to be inserted in the intervertebral space defined between two neighboring vertebrae to be mutually secured, so as to restore the height and the angle of the lordosis of the vertebral segment defined by the two neighboring vertebrae and a stabilizing plate ( 17 ) provided, at each of its ends, with at least a passage hole ( 18 ) for an anchoring screw, the plate ( 17 ) and the implant ( 4 ) being provided with mutual assembly means, such that after assembly, the stabilizing plate ( 17 ) extends on each side of the implant to enable the stabilizing plate to be anchored on the neighboring vertebrae through the screws, characterized in that it comprises spacing means ( 30 ), interposed between the stabilizing plate ( 17 ) and the implant ( 4 ), to enable the stabilizing plate to be positioned at a specific distance relative to the implant.
Patent DE-60305066-D1 (DE)
Inventor: LESTARQUIT LAURENT
IPC: G01S1/68
Filed: 2003-12-12
Granted: 2006-06-08
Abstract: The method involves modulating four false random navigation codes at a bit rate of 0.5 megahertz on a higher frequency carrier based on 8-PSK modulation of constant amplitude with a modulation frequency such that 8fc is at most fM. The navigation codes (C1, C1, C2, C2) are modulated in quadrature to the frequency f1= fp-fM/8 and f2= fp-fM/8, respectively. The modulated navigation signal presents a constant envelope.  The center frequency fc = Max (fci), where fci is the rate of code bits (fc1, fc1, fc2, fc2). Each fci value is such that fM = Nixfci, where Ni is an integer number greater than or equal to 8. An Independent claim is also included for a device for generating a modulated navigation signal.
Patent DE-60318808-D1 (DE)
Inventor: DANIELMEIER KARSTEN
IPC: C08G65/333
Filed: 2003-11-22
Granted: 2008-03-13
Abstract: The present invention relates to polyaspartate mixtures containing  a) 5 to 50 equiv.%, based on the total equivalents of aspartate groups, of a polyoxypropylene polyaspartate corresponding to the formula <CHEM> wherein X1 represents the residue obtained by removing the amino groups from a polyoxypropylene polyamine having a functionality of n, R1 and R2 are identical or different and represent organic groups which are inert to isocyanate groups at a temperature of 100 DEG C or less, R3 and R4 are identical or different and represent hydrogen or organic groups which are inert towards isocyanate groups at a temperature of 100 DEG C or less and n is 2 to 4, and b) 50 to 95 equiv.%, based on the total equivalents of aspartate groups, of a polyether polyaspartate corresponding to the formula I wherein X1 represents the residue obtained by removing the amino groups from a polyether polyamine having a functionality of n and a number average molecular weight of less than 5000, wherein the amino groups are attached to primary carbon atoms and the ether groups are separated by at least two carbon atoms.  <??>The present invention also relates to a process for preparing these polyaspartate mixtures and to the polyureas prepared by reacting the polyaspartate mixtures and optionally other isocyanate-reactive compounds with polyisocyanates.
Patent DE-60323656-D1 (DE)
Inventor: LVOVICH VADIM F
IPC: G01N33/28
Filed: 2003-10-14
Granted: 2008-10-30
Abstract: A method for determining quality and condition of a highly resistive fluid in transportation and industrial equipment. The method uses apparatus that applies a multitude of oscillating voltage signals at determined frequencies and offsets to electrodes immersed in the fluid and quantifies fluid response to the signals. The method monitors response of the fluid to a preferred three fixed electrical signals applied by the apparatus, a high and a medium frequency signal with zero offset voltage and a low frequency signal with an offset voltage. For apparatus or applications where the monitored fluid is not controlled to constant temperature, the method includes correcting the temperature sensitive fluid responses for temperature variations for the fluid quality and condition determination. The method can also include determining when essentially complete fluid exchanges are made to the equipment without need for additional input.
Patent DE-60330347-D1 (DE)
Inventor: VIGIL DENNIS M
IPC: A61F2/958
Filed: 2003-06-04
Granted: 2010-01-14
Abstract: A device for folding a balloon of a balloon catheter during balloon deflation includes a band and a plurality of elongated fingers that are attached to the band. The band includes a midsection and a pair of overlaps with each overlap extending from the midsection to a respective end of the band. The band is folded into an annulus wherein the overlaps are juxtaposed and can be joined together by soldering, welding or adhesive bonding. The annulus is attached to the catheter tube of the balloon catheter with the fingers extending over the balloon in a substantially same axial direction. In operation, the fingers are moveable between an unstressed configuration, when the balloon is deflated, and a stressed configuration, when the balloon is inflated. In a stressed configuration, the fingers urge against the balloon and are biased toward the stressed configuration to return to an unstressed configuration.
Patent DE-60333028-D1 (DE)
Inventor: VERLEE DONALD
IPC: E02B3/12
Filed: 2003-11-07
Granted: 2010-07-29
Abstract: An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The method of loading beneficial agent includes dispensing beneficial agent in a raster format and/or an off-axis format along a dispensing path.
Patent DE-60336998-D1 (DE)
Inventor: BOUCHAT CHRISTELE
IPC: H04L12/28
Filed: 2003-07-03
Granted: 2011-06-16
Abstract: The present invention is related to a method to perform a duplicate MAC address check and to change dynamically a MAC address in an aggregation network containing at least a server computer device and a client device, comprising the steps of:Sending from said client device to a server computer device a message containing the MAC address of said client computer device,Retrieving said MAC address from said message at said server computer device,Checking if said MAC address is already in use (by a user) in said network or if said server computer device wants to change all MAC addresses in said network,If so, sending from said server computer device to said client device a message containing a new MAC address for said client,Overwriting said MAC address with said new MAC address in said client computer device.
Patent DE-68901146-D1 (DE)
Inventor: JAUBERT JEAN
IPC: C02F3/10
Filed: 1989-02-06
Granted: 1992-05-14
Abstract: The water to be treated circulates inside the reactor in the space (2) situated above the partition (1); it is aerated and stirred by a sparger (3); it enters the reactor through the orifice (4) and leaves it through the orifice (5); the volume of confined, oxygen-depleted water occupies, in the lower part of the reactor, the space (6) situated below the partition (1); it has, in its thickness, an oxygen-supersaturated layer (10) occupied by microalgae and aerobic microorganisms; an oxygen-rich zone (11) occupied by aerobic microorganisms; an oxygen-depleted zone (12) occupied by anaerobic microorganisms; and an intermediate zone (13) occupied by aerobic microorganisms and anaerobic microorganisms. 
<??>The invention applies especially, in a closed circuit, to aquariums and, in an open circuit or in a closed circuit, to water treatment. 
<IMAGE>
Patent DE-68904482-D1 (DE)
Inventor: MANZER LEO ERNEST
IPC: B01J27/125
Filed: 1989-06-29
Granted: 1993-03-04
Abstract: An improved process for the manufacture of 1,1,1-trifluorodichloroethane and/or 1,1,1,2-tetrafluorochloroethane by contacting in the gaseous phase at about 250 DEG C to about 450 DEG C a selected pentahaloethane with hydrogen fluoride in the presence of a catalyst composition comprising a catalytically effective amount of a selected metal in combination with a high fluorine content aluminum-containing compound, the reaction being conducted under controlled conditions whereby the production of pentafluoroethane is minimized.
Patent DE-68914549-D1 (DE)
Inventor: HISLOP JOHN ROBERT
IPC: A23L27/12
Filed: 1989-08-22
Granted: 1994-05-19
Abstract: Process for making shelf-stable, orange-juice containing beverages, which approach the quality of freshly-squeezed orange juice, while using commercially available sources and equipment. The obtained products have a titratable orange oil content of less than 0.015%, and are further characterised by a relatively high ratio of desirable to less desirable specific flavour and aroma components.
Patent DE-68916828-D1 (DE)
Inventor: OMATA SATOSHI
IPC: H03B5/30
Filed: 1989-03-31
Granted: 1994-08-25
Abstract: This invention discloses a signal processing apparatus which has N nonlinear oscillators, a circuit for coupling the N nonlinear oscillators in a loop-like form, a circuit for shifting the phase of the output signal of a particular nonlinear oscillator from among the N nonlinear oscillators in correspondence with an input signal, and a circuit for outputting the output of at least one oscillator of the N nonlinear oscillators as the output of the signal processing apparatus. This apparatus has capability to effect analog conversion, modulation or storage of an input signal.
Patent DE-68925401-D1 (DE)
Inventor: TSUTSUMI YASUHIRO OMRON TATEIS
IPC: G06F1/035
Filed: 1989-09-26
Granted: 1996-02-22
Abstract: A fuzzy inference engine has a plurality of individual inference sections (10) and a concluder section (110) for integrally processing outputs from the inference sections. In order for the inference sections to share membership function circuits and membership function generator circuits, these circuits are arranged in arrays disposed at location external with respect to the inference sections, which selectively use outputs from membership function cirucit arrays (11, 12, 13) and the membership function generator circuit array (15).
Patent DE-68925494-D1 (DE)
Inventor: DAWSON MICHAEL JOHN
IPC: A61K31/335
Filed: 1989-05-09
Granted: 1996-03-07
Abstract: Compounds of formula (1) <CHEM>  and salts thereof, wherein  R<1> represents a methyl, ethyl or isopropyl group;  Y<1> is -CH2-, Y<2> is -CH- and X represents <CHEM> where R<2> represents a hydrogen atom or a group OR<8> (where OR<8> is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R<3> represents a hydrogen atom, or R<2> and R<3> together with the carbon atom to which they are attached represent >C=0, >C=CH2 or >C=NOR<9> (where R<9> represents a hydrogen atom, a C1-8 alkyl group or a C3-8 alkenyl group) and the group >C=NOR<9> is in the E configuration] or -Y<1>-X-Y<2>- represents -CH=CH-CH- or -CH2-CH=C-; R<4> represents a group OR<8> as defined above and R<5> represents a hydrogen atom, or R<4> and R<5> together with the carbon atom to which they are attached represent >C=0 or >C=NOR<9a> (where R<9a> is as defined above for R<9>); R<6> represents a hydrogen atom and R represents -CH2OH, -CHO, -CO2H or a carboxylic acid ester or amide group; or R<6> represents a hydroxyl group and R represents a methyl group; and R<7> represents a hydrogen atom or when R represents a group -CH2OH then R<7> may also represent a hydroxyl group. The compounds may be used to control nematode, acarine, insect or other pests.
Patent DE-68927073-D1 (DE)
Inventor: DEVAUCHELLE GERARD
IPC: C12N15/866
Filed: 1989-05-31
Granted: 1996-10-10
Abstract: The invention relates to a baculovirus modified by inserting into its genome a suitable restriction fragment under the control of a strong tardy promoter of the gene of at least one of the proteins associated with the baculovirus (polyedrine, protein P10). Process for obtaining such a modified baculovirus. Use of such a modified baculovirus as an unfilled expression vector ready to receive at least one sequence of at least one foreign gene which it is desired to express. <IMAGE>
Patent DE-69001830-D1 (DE)
Inventor: SEDLMAIR GERHARD
IPC: A63C7/10
Filed: 1990-02-20
Granted: 1993-07-15
Abstract: Ski brakes (1, 2) useful in interlocking skis of a pair together comprising two shaped members (7, 8) having actuator (11, 12) and braking arm (13, 14) portions separated by an intermediate portion (9, 10). The members are rotatably mounted in a base plate (5, 6), the free ends of the actuator arm portions being axially aligned and connected by a coil spring (17), while the braking arms are provided with shoulders (18, 19) adapted to engage longitudinal edges (20, 21) of the skis. To accomplish interlocking, the running surfaces of skis provided with the brakes are brought together in a face-to-face relationship, causing the braking arms (13, 14) on one of the skis (3, 4) to overlie the braking arms on the other ski. This results in bringing the shoulders of the brake of the latter ski into engagement with longitudinal edges of the former ski, thereby locking the skis together.
Patent DE-69004421-D1 (DE)
Inventor: REDLICH ROBERT W
IPC: G01D5/20
Filed: 1990-12-22
Granted: 1993-12-09
Abstract: A new linear position transducer is disclosed which is substantially identical to the transducer described and illustrated in U.S. Patent No. 4,667,158, except that the tubular layer contained between the coil and the outer shield comprises a silicon steel foil wrapped around the coil which has the effect of reducing the reluctance of this space to a low value. An electrical insulator is applied to one side of the silicon steel foil to prevent the creation of a current path between the coil and the outer shield of the transducer. <IMAGE>
Patent DE-69011497-D1 (DE)
Inventor: MILLER STEPHEN
IPC: C10G67/02
Filed: 1990-08-13
Granted: 1994-09-15
Abstract: The present invention relates to a hydrocracking and isomerization process for preparing low pour point middle distillate hydrocarbons and lube oil from a hydrocarbonaceous feedstock boiling above about 600 DEG  F. by contacting the feedstock with a catalyst containing an intermediate pore size silicoaluminophosphate molecular sieve and a hydrogenation component.
Patent DE-69025946-D1 (DE)
Inventor: VOGELSTEIN BERT
IPC: A61K47/48
Filed: 1990-08-15
Granted: 1996-04-18
Abstract: The epidermal growth factor receptor (EGFR) gene is amplified in 40% of malignant gliomas and the amplified genes are frequently rearranged. The genetic alterations associated with these rearrangements are characterized in five malignant gliomas. In one tumor, the rearrangement resulted in the deletion of most of the extracytoplasmic domain of the receptor, resulting in a hybrid mRNA between new sequences and the truncated EGFR. The predicted amino acid sequence of the protein from this tumor was remarkably similar to that described for several viral erb-B oncogenes. Four other tumors were noted to have internal deletions of the EGF receptor gene. These rearrangements brought about in-frame deletions affecting either of two cysteine-rich domains in the extracytoplasmic portion of the molecule. The clonal nature of these alterations, and the fact that identical alterations were seen in more than one tumor, suggests a role for these mutant receptor proteins in tumorigenesis. Furthermore, these studies document the existence of tumor specific cell molecules resulting from somatic mutation.
Patent DE-69028037-D1 (DE)
Inventor: OHSAKI ICHIRO
IPC: G03G9/087
Filed: 1990-04-30
Granted: 1996-09-19
Abstract: A color toner for developing an electrostatic latent image, which includes a binder resin, a xanthene-type dye and a compound containing a phenolic -OH (hydroxyl) group.
Patent DE-69028938-D1 (DE)
Inventor: BONALDI ANTONIO
IPC: C07J9/00
Filed: 1990-02-22
Granted: 1996-11-28
Abstract: A process for preparing 3-alpha-7-beta-dihydroxycholanic acid from a crude product containing up to 15% by weight of 3-alpha-7-alpha-dihydroxycholanic acid and up to 1% by weight of 3-alpha-hydroxycholanic acid, by esterifying with methanol, crystallizing from an aromatic solvent and recrystallizing from a mixture of methanol, aromatic solvent and water.
Patent DE-69031669-D1 (DE)
Inventor: EGGLER JAMES F
IPC: C07D277/64
Filed: 1990-06-14
Granted: 1997-12-11
Abstract: Compounds of the formula <CHEM> and pharmaceutical compositions comprising them, wherein R<1>, R<2>, R<3>, W, X and Z are as defined below. The compounds are inhibitors of 5-lipoxygenase enzyme and antagonists of Ieukotriene B4, leukotriene C4, leukotriene D4 and leukotriene E4.
Patent DE-69110186-D1 (DE)
Inventor: KITZINGER FRANK
IPC: E21C37/18
Filed: 1991-03-05
Granted: 1995-07-13
Abstract: A blasting method which comprises delivering electrical energy at a rate of at least 100 megawatts per microsecond until a peak power of at least 3 gigawatts is reached across the gap of two poles of a coaxial electrode assembly immersed in an electrolyte within a confined area of a substance to be blasted. A dielectric break-down of the electrolyte in the confined area is produced resulting in the formation of plasma within the confined area which creates a pressure sufficient to blast the substance in the manner of a high explosive charge.
Patent DE-69112147-D1 (DE)
Inventor: CLAYMAN RALPH VICTOR
IPC: A61B17/22
Filed: 1991-06-19
Granted: 1995-09-21
Abstract: A surgical tissue bag (301) for percutaneously debulking large volumes of tissue contained within the bag (301). The tissue bag (301) comprises two layers of material, an inner layer of a puncture-resistant material and an outer layer of moisture-proof material for containing cells and fluid therein. The bag (301) material is foldable and flexible for insertion through an access sheath (302) into the surgical site and for forming a gas-tight seal when extended through the access sheath (302) or puncture site. A drawstring (310) is attached to the open end of the bag (301) to close the bag (301) when the tissue is contained therein and pulled through the puncture site in the outer surface of the skin (304). After the closed open end of the bag (301) is pulled through the puncture site, the closed end is fanned out against the outer layer of the skin, and a morcellator is inserted into the bag for debulking the large volume of tissue. The open end of the bag is continully fanned out to maintain a compact and tight containment of the tissue and fluid remaining in the bag. The morcellation process is continued until the entire volume of tissue is removed at which time the remaining portion of the bag (301) is completely removed from the surgical site area.
Patent DE-69126740-D1 (DE)
Inventor: FOURQUIER DOMINIQUE
IPC: C08F299/04
Filed: 1991-04-25
Granted: 1997-08-14
Abstract: Liquid resin compositions appropriate for moulding objects reinforced by glass fibres and which may be pigmented, comprising an unsaturated polyester, a copolymerizable monomer and a partially hydroxylated alkyl methacrylate polymer. The polymer selected is a hydroxylated alkyl methacrylate polymer which is soluble in the monomer and miscible with the unsaturated polyester. Application to the fabrication of moulded objects by mass moulding, sheet moulding and by injection.
Patent DE-69132340-D1 (DE)
Inventor: SAKAMOTO SHUICHI
IPC: C07D487/04
Filed: 1991-11-01
Granted: 2000-08-31
Abstract: A pyrazine derivative which inhibits glutamate receptor, represented by general formula (Ia) wherein Z represents C or N, provided that two Zs are not N atoms at the same time; R<1> represents (1a) wherein X represents N or R<8>C, R6 represents H or alkyl, and R<7> and R<8> represent each H, alkyl, nitro or phenyl, or alternatively R<7> and R<8> are combined together to represent butadienylene or 1,4-butylene; R<2> and R<3> represent each H, F, cyano, acyl, nitro, alkyl, morpholino or R<1>; R<4> and R<5> represent each H, hydroxy, alkyl, cycloalkyl, heterocycle, pherryl or Y-substituted alkyl; Y represents hydroxy, acyloxy, F-substituted methyl, cycloalkyl, tetrahydrofuryl, carboxyl, alkoxy carbonyl or NR<9>R<1><0>; and R<9> and R<1><0> represent H or alkyl, or alternatively R<9> and R<1><0> are combined together to represent a 5- or 6-membered cyclic group which may contain oxygen atom(s). <CHEM>