baber/WOPTO huggingface dataset:
Patent HR-P20110524-T1 (HR)
Title: Dihydropyridine compounds for neurodegenerative diseases and dementia
Inventor: GRAY JULIAN A
IPC: A61K31/445
Filed: 2011-07-12
Abstract: The invention provides methods for treating and/or preventing cognitive impairments, dementia, or neurodegenerative diseases and disorders (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis) in patients by administering therapeutically effective amounts of an AMPA receptor antagonist (e.g., 1,2-dihydropyridine compounds) and therapeutically effective amounts of nootropics (e.g., cholinesterase inhibitors) to patients. The invention also provides combinations, commercial packages, and pharmaceutical compositions comprising therapeutically effective amounts of AMPA receptor antagonists (e.g., 1,2-dihydropyridine compounds) and therapeutically effective amounts nootropics (e.g., cholinesterase inhibitors). The 1,2-dihydropyridine compound may be, for example, 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one. The cholinesterase inhibitor may be, for example, donepezil.
Patent SI-1638598-T1 (SI)
Title: ACAPSULAR i P. MULTOCIDA HYAE /i DELETION MUTANTS
Inventor: BRIGGS ROBERT E
IPC: C12N1/00
Filed: 2004-07-02
Abstract: Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumonia in mammals, particularly livestock, ungulates, and companion animals, or fowl cholera in birds, particularly poultry.
Patent SI-1905451-T1 (SI)
Title: Combinations comprising antimuscarinic agents and corticosteroids
Inventor: GRAS ESCARDO JORDI
IPC: A61K31/00
Filed: 2005-05-31
Abstract: A combination which comprises (a) a PDE4 inhibitor and (b) an antagonist of M3 muscarinic receptors which is (3R)-1-phenethyl-3-(9H-xanthene-9-carbonyloxy)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid.
Patent SI-1688237-T1 (SI)
Title: Method for manufacturing plastic foam panels from extruded polystyrene foam material and covered panel
Inventor: WEDI STEPHAN
IPC: B29C48/07
Filed: 2006-02-03
Abstract: Plastic foam sheet is made by extruding expanded polystyrene foam, cutting the strip into rectangular sections, trimming, degassing, sticking sections together at their principal sides to form blocks, cutting at right angles to the joints to form block sheets and bonding these with covering(s) at right angles to the adhesive layers. A method for the production of plastic foam sheet (8) from polystyrene extrusion-foaming material (I), involves (a) extruding foam strip through a rectangular die with the dimensions h x b (h = height; b = width), (b) cutting the strip into sections (3) of length l, trimming and degassing, (c) sticking together at least n (= 2) sections at their principal sides to form rectangular blocks (4) of height (n x h), width b and length l, (d) cutting through the blocks (4) at right angles to the adhesive joints at intervals of s 1, s 1 s 2, s 1 s 2 s m to the side with the height (n x h) so as to form block sheets (8) with the dimensions S m x (n x h) x l and (e) bonding the block sheets (8) with a covering (11) on at least one of the sides at right angles to the adhesive layer(s). Independent claims are also included for covered block sheets obtained by this method, with two reinforced mortar layers as coverings (11) or with at least one metal sheet as covering (11).
Patent SI-2919857-T1 (SI)
Title: Composition for rectal use containing honey and glycerine
Inventor: MERCATI VALENTINO
IPC: A61K35/644
Filed: 2013-11-13
Abstract: The present invention relates to compositions for rectal use comprising honey in a weight percentage up to 95% w/w and glycerine in a weight percentage of between 2-40% w/w for the treatment of constipation in a subject in need thereof. The present invention also relates to a kit of parts comprising such a composition.
Patent SI-3044206-T1 (SI)
Title: (3z,5s)-5-(hydroxymethyl)-1-((2 -methyl-1,1 -biphenyl-4-yl)carbonyl)pyrrolidin-3-one o-methyloxime as oxytocin / vasopressin v1a receptors antagonists for the treatment of preterm labor
Inventor: CHOLLET ANDRE
IPC: C07D207/00
Filed: 2014-07-25
Abstract: The present invention relates to a compound of formula (3Z,5S)-5-(hydroxymethyl)-1-[(2′-methyl-1,1′-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-meth19243yloxime, and/or an active metabolite thereof having antagonist action at the oxytocin receptor and/or vasopressin V1a receptor, to processes for their preparation, pharmaceutical compositions containing them and their use.
Patent DE-3588210-T2 (DE)
Inventor: NICOLOTTI ROBERT A
IPC: C07D207/44
Filed: 1985-10-02
Granted: 1999-11-11
Abstract: Bifunctional coupling agents for joining radionuclide metal ions to biologically useful molecules, including antibody Fab min  fragments are disclosed. The coupling agents contain a maleimide moiety and a paramagnetic or radionuclide chelating moiety. The maleimide can be used to selectively bind to free sulfhydryl groups, or amine groups.
Patent DE-3687948-T2 (DE)
Inventor: BAER BRADFORD WALTER
IPC: C12N15/54
Filed: 1986-11-05
Granted: 1993-06-17
Abstract: Nucleic acid encoding lecFthin:cholestero! acyltransferase is ligated into expression vectors and used to transform host cells for the synthesis of lecithin:chotesterol acyltransferase in recombinant cell culture. Lecithin:cholesterol acyltransferase amino acid sequence variants are described for enhancing the properties of lecithin:cholesterol acyltransferase. Ledthin:cholesterol acyltransferase and its variants are employed in the therapy of conditions characterized by hypercholesterolemia and for the mobilization of cholesterol in vivo.
Patent DE-3789200-T2 (DE)
Inventor: APPELDORN ROGER H C O MINNESOT
IPC: G02B5/124
Filed: 1987-11-13
Granted: 1994-10-06
Abstract: Cube-corner retroreflective article in which the cube-corner retroreflective elements are formed by three intersecting sets of parallel V-shaped grooves (11, 12, 13), at least one of the sets (13) including, in a repeating pattern, at least one groove side angle (132, 133, 134) that differs from another groove side angle (131) of the same set. By the described variation in groove side angle, the array of cube-corner retroreflective elements is divided into repeating sub-arrays that each comprise a plurality of cube-corner retroreflective elements in a plurality of distinctive shapes that retroreflect incident light in distinctively shaped light patterns.
Patent DE-3854503-T2 (DE)
Inventor: ANDO RYO
IPC: G11B27/36
Filed: 1988-03-10
Granted: 1996-02-22
Abstract: A disk recording/reproducing apparatus and a disk recording/reproducing method wherein a recording disk (1) having an absolute address is provided with a program region (6) and a read-in region (7), data such as play data are recorded on the program region (6), the data are recorded on the read-in region (7) using, as catalog data, a start address data of a data unit region where the data have been recorded and a finish address data, and the data on the program region (6) are reproduced from the catalog data in the read-in region (7). An erase inhibit flag is set to the catalog data for each of the data units, whereby the erase inhibit and the erase enable are designated by the erase inhibit flag for each of the data units for the data that are recorded on the program region (6).
Patent DE-3855034-T2 (DE)
Inventor: MANDELL DOUGLAS EVAN
IPC: H03H17/02
Filed: 1988-09-16
Granted: 1996-08-08
Abstract: An adaptive single-bit encoder and decoder has its adaptive function determined by dynamically dividing the message frequency band into delta-sigma and delta modulation regimes of operation. In a practical embodiment this is accomplished by varying the corner frequency of a variable-frequency low-pass filter (14, 14 min ) in a leaky integrator so that below the corner frequency the operation is that of delta-sigma modulation and above the corner frequency the operation is that of delta modulation. An adaptation control circuit (18, 18 min ) removes the clock signal component from the encoded bit stream to provide an analog signal representative of bit stream information or loading for use in generating the control signal. The analog signal is peak rectified (22, 22 min ), smoothed (24, 24 min ), and (optionally) non-linearly processed (26, 26 min ) to provide the control signal.
Patent DE-3877696-T2 (DE)
Inventor: MAY KEITH
IPC: G01N33/52
Filed: 1988-10-28
Granted: 1993-07-08
Abstract: A chromatographic test device for detecting the presence of an analyte in a liquid sample and incorporating at least two liquid-conductive zones (3, 4) which form separate liquid flow paths which deliver separate liquid streams to a region (8) in the test device during the test procedure, wherein control of the relative liquid flows in the separate flow paths is achieved, at least in part, by ensuring that at least one of the liquid flow paths is enhanced or made and/or broken or restricted during the course of the test procedure. Preferably such control is achieved by incorporating a liquid-swellable material (11) which is arranged to swell by contact with liquid sample and/or reagent and thereby to make or break contact between two liquid-conductive zones.
Patent DE-3879594-T2 (DE)
Inventor: CARTER STEPHEN
IPC: G02B21/24
Filed: 1988-09-12
Granted: 1993-09-09
Abstract: There is disclosed a microscope viewing arrangement adapted for exhibition use comprising a console (11) enclosing a microscope arrangement (12) and affording a viewing position (13), remote focussing means (14) operable from the viewing position (13), and a lamp arrangement adapted to illuminate a specimen position, the focussing means, the lamp arrangement (15) and the specimen position (16) being, in use, inaccesible from the viewing position, and information display means (17) adapted to display information relevant to a specimen mounted in the specimen position and to be changed with such specimen.
Patent DE-3880837-T2 (DE)
Inventor: VITALI GIORGIO
IPC: B05B11/00
Filed: 1988-09-30
Granted: 1993-11-04
Abstract: The object of the invention is a manually operated sprayer for liquids suitable for fixing on the opening of a container, comprising a pump (8) which draws liquid from the container by means of appropriate ducts (12, 14) and sends it to a nebulizer nozzle (15) said sprayer also being provided with a duct (16) extending from the opening of the said container to the surrounding air, the outlet (17) of the said duct (16) being able to be closed by a stopper (23), integral with the operating lever (19) of the pump (8) which closes the external outlet (17) of the said duct (16) when at rest. The stopper (23) is located very near to the fulcrum (20) of the lever (19).
Patent TR-199800679-T2 (TR)
Inventor: LAURENT HENRY
IPC: A61P19/00
Filed: 1996-02-09
Abstract: This invention relates to (R)-(-)-methylphenyloxazolidinone derivatives, a process for their production and their use as pharmaceutical agents.
Patent TR-199801201-T2 (TR)
Inventor: KRECH RUDIGER
IPC: C08J9/36
Filed: 1996-12-16
Abstract: Bulus, temel olarak 4,4-MDI'den olusan bir izosiyonat bileseni ve baska standart bilesenler içeren ve iyilestirilmis dinamik-mekanik karakteristikler gösteren mikroselüler bir PLI elastomerine iliskindir.Önerilen elastomer, 100-120  C'lik sicakliklarda, 8 ila 24 saat boyunca isil sertlestirme uygulamasinin ardindan, 20 C/dak'lik bir isitma hiziyla, diferansiyal taramali kabrimetri (DSC) ile ölçüldügünde, minimum alt sinir olarak 130 C ile minimum üst sinir olarak 230 C arasinda degismez bir erime noktasi araligi gösterir ve agirlik olarak % 14-18'lik bir üre içerigine sahiptir.Ayrica iyilestirilmis dinamik-mekanik karakteristiklere sahip bu tür bir mikroselüler PLI elastomerinin üretimine yönelik  bir yöntem ve adi geçen elastomerlerin darbe yumusatici elementlerin üretimde kullanimi da anlatilmistir.
Patent TR-199801607-T2 (TR)
Inventor: BRANDS KARL-DIETER BRANDS VARI
IPC: C23C22/12
Filed: 1997-02-10
Abstract: Özelligi, fosfatizasyon çözeltisinin 0,2 ile 3 gr/l arasinda çinko iyonlari, 3 ile 50 gr/l arasinda fosfat iyonlari, 1 ile 100 mg/l arasinda nikel ve/ veya kobalt iyonlari, bir veya birden fazla akselaratör ve 0,5 gr/l' den fazla olmamak üzere nitrat iyonlari içermesi olan, metal yüzeylerinin püskürtmü veya daldirma yöntemiyle 3 saniye ile 8 dakika arasindaki bir süreyle çinko içeren bir fosfatizosyan çözeltisi ile temas ettirildigi, çelik, galvanizli veya alasimla galvanize edilmis çelik ve/veya alüminyumdan mamul metal yüzeylerinin fosfatizasyonu için yöntem. Fakültatif katki maddeleri lityum, bakir ve/veya mangandir.
Patent TR-199900851-T2 (TR)
Inventor: MOSS MICHAEL ALAN JOHN
IPC: C11D1/52
Filed: 1997-10-02
Abstract: Bu bulus bir proteolitik enzimi ve R1R2R3R4N+X- formülünün bir ya da daha çok katyonik sürfaktanini ihtiva eden deterjan bilesimleri ya da bilesenlerine iliskindir, bu formülde, R1, 6'dan fazla olmayan karbon atomuna sahip olan bir hidroksialkil grubudur; her R2 ve R3, bagimsiz olarak C1-4 alkil ya da alkenilden seçilmektedir; R4. bir C5-11 alkil ya da alkenildir; ve X- bir karsi iyondur.
Patent DE-60003301-T2 (DE)
Inventor: SUCCI OMAR
IPC: B31B50/10
Filed: 2000-07-07
Granted: 2004-04-29
Abstract: A unit (1) for processing a web (2) of packaging material, and having at least a first station (3) for forming a number of through holes (4) in the web (2); a second station (6) for sealing the holes by applying respective opening devices (7, 8); a feed device (10) for step feeding the web (2) along a path (P) through the first and second station (3, 6); a position sensor (21) generating a presence signal (S) indicating the passage, past the sensor (21), of reference elements (C; 4) carried by the web (2) and bearing a predetermined relationship with the holes (4); a control device (20) for controlling the feed device (10) in response to the presence signal (S); and actuating means (22) cooperating with the second station (6) to move the second station in a direction parallel to said path (P), and activated by the control device (20) to adjust the position of the second station (6) as a function of the presence signal <IMAGE>
Patent DE-60006981-T2 (DE)
Inventor: GUNNARSSON CENNETH
IPC: B65G47/44
Filed: 2000-09-11
Granted: 2004-10-28
Abstract: A feeder arrangement for the individual feeding of timber pieces ( 10 ) to a downwardly moving conveyor ( 2 ) includes an incoming conveyor ( 7 ) and projecting carriers ( 23 ) on the downwardly moving conveyor ( 2 ). The incoming conveyor ( 7 ) is disposed for the feeding of timber pieces ( 10 ). The carriers ( 23 ) incline obliquely downwards and outwards from the downwardly moving conveyor ( 2 ). A curved guide space ( 21 ) is disposed to overlap, with a lower end portion, an upper portion of the downwardly moving conveyor ( 2 ). The angle of curvature of the guide space ( 21 ) is so great that the upper side of a timber piece ( 10 ) which comes to guide space ( 21 ) will be turned to face downwards when the timber piece ( 10 ) rests on a carrier ( 23 ). The incoming conveyor ( 7 ) has an end portion which is turned to face towards the guide space ( 21 ) and which is approximately horizontal.
Patent DE-60009556-T2 (DE)
Inventor: HANSSON KRISTER
IPC: B44F9/02
Filed: 2000-11-27
Granted: 2005-02-03
Abstract: Surface elements comprising a decorative upper layer and a supporting core are disclosed. In such surface elements the decorative upper layer can comprise a digitally applied wood grain pattern made up of at least four colors, said pattern being applied to an underlying white ground coating provided on said supporting core, said pattern comprising at least one of visually simulated knots, cracks, flaws and grain. In such surface elements the decorative upper layer can further comprise an at least partly translucent wear layer arranged over said pattern, said wear layer consisting of a cured substance comprising silicon oxide. In such surface elements the decorative upper layer can further be provided with a surface structure increasing the realism of said wood grain pattern, being directed in accordance with the direction of said pattern and being in the form of narrow elongated recesses simulating the pores of wood.
Patent DE-60013636-T2 (DE)
Inventor: STROBER WARREN
IPC: A61P17/06
Filed: 2000-11-09
Granted: 2005-09-15
Abstract: The present invention provides a method of treating or preventing inflammation in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. The present invention also provides a method of decreasing the activity of interferon gamma in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Further provided is a method of decreasing the activity of IL-12 in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Additionally, the present invention provides a method of treating or preventing a Th1 T-cell mediated autoimmune disorder in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B.
Patent DE-60014547-T2 (DE)
Inventor: DOWNES KEVIN W
IPC: B60N2/30
Filed: 2000-10-19
Granted: 2005-02-03
Abstract: A folding seat is described for the cab of an agricultural vehicle. The seat 10 comprises a mounting bracket 22 secured by bolts 25 to an inclined surface in the cab, such as part of the wheel arch. A seat member 16 is pivotably mounted at its rear end on the mounting bracket 22 for pivotal movement between a horizontal operative position and an inclined storage position in which the seat member lies against the mounting bracket 22. A stay 30 is mounted to pivot between an operative position in which it extends vertically from the mounting bracket 22 to the seat member 16 in order to support the weight of the seat member on the mounting bracket and a storage position in which it lies between the mounting bracket 22 and the seat member 16. <IMAGE>
Patent DE-60031008-T2 (DE)
Inventor: ANDERSEN JESPER
IPC: H04M1/02
Filed: 2000-01-28
Granted: 2007-01-04
Abstract: An electronic radiotelephone comprising a first housing, a second housing, and an inner housing having retaining means for retaining to the inner housing the electronic components of the radiotelephone; and first releasable attaching means for releasable attaching the first housing to the inner housing, wherein the first housing, when attached to the inner housing, is presented towards a user during operation of the radiotelephone; and second releasably attaching means for releasable attaching the second housing to the inner housing, wherein the second housing, when attached to the inner housing, faces away from the user during operation of the radiotelephone. <IMAGE>
Patent DE-60038741-T2 (DE)
Inventor: MINAKATA HIROYUKI
IPC: A61P1/00
Filed: 2000-07-25
Granted: 2009-07-02
Abstract: Tachykinin peptide isolated and purified from the posterior salivary gland Octopus vulgaris which is mollusc. The tachykinin peptide provides a new approach for developing medicaments and pesticides through studies on the structural activity correlation at the molecular level, is characterized by:     (1) number of an amino acid resides is 12;   (2) N terminal of the peptide is Lys; (3) an amino acid sequence of 5 amino acids from C terminal is represented by the following amino acid sequence (I), <IMAGE> (wherein, Xaa is Val, Ile, Phe or Tyr), especially following amino acid sequence (1) and (2) are provided: <IMAGE>   <IMAGE>   <IMAGE>
Patent DE-60102590-T2 (DE)
Inventor: ROSENBERG JOERG
IPC: A61K31/496
Filed: 2001-08-02
Granted: 2005-04-21
Abstract: A solid dosage form for application in the oral cavity, comprising a poorly bioavailable pharmaceutical active ingredient dispersed in a pharmaceutically acceptable matrix.
Patent DE-60109688-T2 (DE)
Inventor: ROBERTSON IAN
IPC: E01B37/00
Filed: 2001-07-11
Granted: 2006-03-23
Abstract: Topographical reference points (8) are established and used as sites for laser measuring stations (3) which use reflectors (7) on an installation vehicle (1). Distance and angle data are transmitted (9) from the measuring station to a receiver (30) on the installation vehicle and used by a computer (31) to control the orientation in three orthogonal axes of installation arms (5) which insert saddles (2) in fresh concrete (10) Independent claims are made for equipment which uses the installation method
Patent DE-60111070-T2 (DE)
Inventor: WOUTERS-WASIAK KATIA
IPC: C02F3/30
Filed: 2001-09-25
Granted: 2005-10-20
Abstract: A process for purifying wastewater including the step:a) rating the tanks and the aeration means on the basis of the lowest pollution load, referred to as the low load, which corresponds to the plant load during dry weather;b) running the plant during dry weather, or at low load, according to the nitrogen treatment method in a tank with biological dephosphatation;c) running the plant during wet weather, or at high load, by performing the physicochemical phosphorus treatment technique and the nitrogen treatment technique in two tanks, andd) controlling the plant by detecting the load situation it is in (high load or low load) and to adapt the operating configuration of the tanks to the actual load situation.
Patent DE-60114623-T2 (DE)
Inventor: MASSEE JOHAN
IPC: B21D53/84
Filed: 2001-07-20
Granted: 2006-07-13
Abstract: The invention relates to a forming machine at least provided with a clamping device for clamping a hollow workpiece having at least one open end and a first forming tool which can be placed into contact with the outer surface of the workpiece and with which the workpiece can be deformed. The clamping device can be rotated about a first axis and moved with respect to this first axis. Thus, the forming machine can be of relatively straightforward design and operate at high rotational speeds, even when a tool head equipped with a relatively large number of rollers is being used. The invention further pertains to a method wherein the clamping device can be moved with respect to the said first axis.
Patent DE-60114874-T2 (DE)
Inventor: HOUSTON J GRAEME
IPC: A61F2/06
Filed: 2001-12-13
Granted: 2006-08-10
Abstract: There is disclosed a method for configuring or reconfiguring branches in tubing in which the axes of at least two components of the branched structure are arranged askew.
Patent DE-60116478-T2 (DE)
Inventor: FOGUET RAFAEL
IPC: C07H19/10
Filed: 2001-03-13
Granted: 2006-09-07
Abstract: The invention describes a prophylactic treatment of cerebral ischemia with CDP-Choline in patients who have undergone major surgery or are at risk of suffering an acute ischemic event.
Patent DE-60120508-T2 (DE)
Inventor: BOUDEWIJNS J
IPC: H03M1/44
Filed: 2001-11-09
Granted: 2007-01-11
Abstract: A switched capacitor pipeline AD-converter whose cells comprise means for multiplying the analog input signal by a factor 2. The multiplying means comprise first and second capacitors wich are each loaded by the input signal. For generating the cell output signal the voltages of the capacitors are added without substantial charge transfer between the capacitors.