baber/WOPTO huggingface dataset:
Patent EP-0428700-B1 (EP)
Inventor: DE CASTIGLIONE ROBERTO
IPC: C07K1/06
Filed: 1990-06-12
Granted: 1994-05-04
Abstract: A peptide of formula (I), wherein R is a group of the formula 4-(ClCH2CH2)2N-C6H4-CO-, 3-(ClCH2CH2)2N-C6H4-CO-, ClCH2CH2NHCO-, ClCH=CH-CO-, BrCH=CH-CO-, CH2=CClCO-, CH2CBrCO- (cis/trans isomers), (a), CH=C-CO-, ClCH2CH2CH2n(NO)CO-, or ClCH2CO-CH(R1)NHCO(CH2)2CO-; A = valence bond, or Gly, Leu-Gly, Arg-Leu-Gly, Gln-Arg-Leu-Gly; B = valence bond or Asn or Thr; C = Gln or His; X = Gly or ala; Y = valence bond or His(R2), his(R2), Phe, phe, Ser, ser, Ala or ala; T = valence bond or Leu, leu, Phe or phe; W is a group of the formula OH, NH2, NH(CH2)4CH3, H(CH2)2C6H5, Met-R3, Leu-R3, Ile-R3, or Nle-R3; R1 = H, linear or branched alyphatic chain having for 1 to 11 carbon atoms, benzyl or phenyl group; R2 = H or Tos, Dnp or Bzl and R3 = NH2, OH, OCH3 or NHNH2 and pharmaceutically acceptable salts are bombesin antagonists. Their preparation and pharmaceutical compositions containing them are also described.
Patent EP-0489049-B1 (EP)
Inventor: WUELKNITZ PETER
IPC: A61K8/43
Filed: 1990-08-16
Granted: 1994-12-07
Abstract: PCT No. PCT/EP90/01346 Sec. 371 Date Feb. 25, 1992 Sec. 102(e) Date Feb. 25, 1992 PCT Filed Aug. 16, 1990 PCT Pub. No. WO91/02513 PCT Pub. Date Mar. 7, 1991.Toothpastes containing 10 to 60% by weight of a polishing agent, 2 to 20% by weight of a humectant, 0.5 to 5% by weight water-soluble consistency regulators, 0.02 to 0.5% by weight antibacterial biguanides and 1 to 5% by weight other additives from the group consisting of surfactants, flavoring oils and sweeteners show particularly high biguanide availability if they contain predominantly (alpha)-aluminium oxide trihydrate as the polishing agent, nonionic polysaccharide derivatives as the consistency regulators, an alkyl glycoside and, optionally, a nonionic solubilizer for the flavoring oil as surfactants and L-aspartyl-L-phenyl alanine methyl ester as sweetener.
Patent EP-0446313-B1 (EP)
Inventor: RUSSELL-JONES GREGORY JOHN
IPC: C07K14/245
Filed: 1990-08-24
Granted: 1996-07-31
Abstract: PCT No. PCT/AU90/00373 Sec. 371 Date Jun. 25, 1991 Sec. 102(e) Date Jun. 25, 1991 PCT Filed Aug. 24, 1990 PCT Pub. No. WO91/02799 PCT Pub. Date Mar. 7, 1991.This invention relates to the preparation of novel fusion proteins which comprise an analogue of LHRH and TraTp or an analogue of TraTp. The fusion proteins of the invention are useful as components of vaccines for the inhibition or control of reproductive functions in vertebrate hosts. The invention also relates to polynucleotide molecules encoding the fusion proteins, to transformant hosts expressing the fusion proteins and to methods of inhibiting or controlling reproductive function in vertebrate hosts using the fusion proteins or vaccines of the invention.
Patent EP-0442259-B1 (EP)
Inventor: SOHNER HAROLD K
IPC: H04B5/00
Filed: 1991-01-09
Granted: 1994-07-27
Abstract: A regenerative RF bi-directional communications system (10) is provided for establishing RF coverage within a RF block tunnel area (12). The system uses a plurality of cascaded amplifier stages (18) for periodically regenerating signals which are transmitted and received along a series of radiating cable length (16) which link base station transceivers (14) to hand-held or like mobile communication units. An intermediate frequency distribution system is used so that the required level of amplification is achieved through the several cascaded amplifier stages (18) at the level of low-power IF signals generated from the original RF signals in conjunction with the appropriate oscillator and pilot signals. The IF distribution system restricts the cascading effect occurring due to the plurality of cascaded amplifier stages on the relatively low-power IF signals, thereby producing a negligible amount of intermodulation. <IMAGE>
Patent EP-0439085-B1 (EP)
Inventor: SOVAK MILOS
IPC: B23D61/18
Filed: 1991-01-21
Granted: 1994-06-01
Abstract: The invention concerns a cutter link (31) for a saw chain, comprising a base member (36) having holes (34, 35) therethrough for connecting links together by means of pintles (13); a raker (42) formed at the forward end of said base member (36) above said holes (34, 35) and having a rearwardly facing end (44); and a body (37) formed rearwardly of said raker (42) and spaced therefrom, the forward end (41) of said body (37) having a cutting edge which is generally round and facing the rearwardly facing end (44) of said raker (42), said cutting edge being of generally the same shape as said rearward facing end (44) of said raker (42). <IMAGE>
Patent EP-0442395-B1 (EP)
Inventor: MENKE WILHELM
IPC: F41J5/052
Filed: 1991-02-08
Granted: 1996-11-13
Abstract: The dartboard comprises a disc divided by radial spokes (1) and concentric hoops for defining a number of fields, each incorporating a spring-loaded, axially displaced segment (4) and a contact plate (9) with contacts indicating a strike of the respective segment (4). The latter has at least one attached pin (11) brought into contact with the contact plate (9) upon its axial displacement in response to a strike, with a rubber mat (10) between the rear of the segment (4) and the surface of the contact plate (9). An adapter plate (12) fits between the rubber mat (10) and the rear of the segment (4) incorporating bores for each of the pins (11), guiding the axial movement of the latter.
Patent EP-0444587-B1 (EP)
Inventor: HAECKER HANS-EUGEN
IPC: D21F1/00
Filed: 1991-02-26
Granted: 1995-05-17
Abstract: A hook (10) for a separator for the successive pick-up and separation of threads (1, 2, 3) held in a row has a leading edge (12) and one or two hook-shaped recesses (13, 14) in the leading edge (12). To improve the reliability, the recess (13, 14) has a depth (Y) in the direction of movement of the hook (10) which is greater than half the width (X) of the recess (13, 14). A deflector edge (16) extends at an angle of 15 to 90 DEG  relative to the direction of movement of the hook (10) between the hook tip (17) and the leading edge (12). The hook tip (17) can be rounded with a radius of up to 10% of the width (X) of the hook-shaped recess (13, 14). 
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Patent EP-0454962-B1 (EP)
Inventor: WAGNER HANS GRUNDIG E M V MAX
IPC: G01R31/308
Filed: 1991-02-27
Granted: 1995-05-24
Abstract: In automatic insertion devices, testing the printed circuit cards before and after soldering constitutes an important factor in the production process. It is therefore necessary to specify test procedures which guarantee reliable evaluation at different stages of production. In the method according to the invention, reliable statements about the presence or the correct position of the components can be made by assessing the relative position of the components with respect to the terminal areas. For this purpose, the test specimen is illuminated without shadows by means of a planar, diffuse light source. The parts of the terminal areas not covered reflect the light very strongly. In this way, it is possible by recording an image of the printed circuit card to be tested and evaluating the video signals of the parts, not covered by the components, of the terminal areas with respect to their size and shape to reach a conclusion on the absence of defects in the printed circuit card. <IMAGE>
Patent EP-0448020-B1 (EP)
Inventor: GUINAND JACQUES
IPC: H04J3/16
Filed: 1991-03-18
Granted: 1997-09-03
Abstract: This elementary switching unit includes, for each incoming frame transmission medium: 
 
  - means of extracting signals consisting of multiplexing units to be cross-connected from the incoming frames, 
  - a memory (1), referred to as the memory for signals consisting of multiplexing units to be cross-connected, and which is able to hold at least N signals, where N denotes the period of the stream of lowest bit rate of the multiplexing hierarchy, 
  - means (2, 3) for ensuring writing of this memory, in synchronism with the extraction rate, to distinct addresses in respect of signals constituting distinct multiplexing units to be cross-connected, and to identical addresses in respect of signals constituting a same multiplexing unit to be cross-connected, the frequency of rewriting of each address being related to the period of repetition of the signals written to this address, 
  - means (20, 21, 22) for ensuring reading of this memory, in synchronism with the rate of insertion into the outgoing frames of signals constituting multiplexing units to be cross-connected, at addresses determined by the said distribution law. 
 
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Patent EP-0482861-B1 (EP)
Inventor: TAYLOR WARREN
IPC: A61B17/12
Filed: 1991-10-21
Granted: 1997-03-05
Abstract: A holder (cartridge) 10 for storing and retaining a plurality of hemostatic clips 20. The holder is produced as an integrally molded unitary piece having a pluarlity of longitudinally spaced chambers 18, each having a central post 23 to support a clip and integrally formed guiding means for guiding the jaws of an associated forceps-type clip applier 22 by which a clip within a selected chamber may be removed from the cartridge. A pair of opposing projections or protrusions 81, 82 are formed in the walls of each clip chamber at a point spaced above the central post, the projections serving to loosely retain a clip in the chamber between the projections and the central post. <IMAGE>
Patent EP-0478450-B1 (EP)
Inventor: RUGGIU GILLES
IPC: C12Q1/6869
Filed: 1991-09-25
Granted: 1994-12-14
Abstract: Method for the sequencing of elements forming a linear or linearised and ordered biological sequence such as a DNA fragment, the method comprising the marking of a plurality of identical sequences by a set of specific markers, the efficiency of such marking being lower than 100 %, the sequential detection and identification of the markers associated with the elements of said sequences in order to obtain lacunar or incomplete sequences of marked elements, and the reconstitution of the complete sequence, by calculating from said lacunar sequences the probabilities of presence of elements in the complete sequence and by retaining the elements whose probabilities of presence approximate 1 or are equal to 1 whereas the probabilities of presence of other elements are close to 0 or equal to 0.
Patent EP-0502927-B1 (EP)
Inventor: KRAUS MATTHIAS H
IPC: A61K47/48
Filed: 1990-11-30
Granted: 1998-03-11
Abstract: A DNA fragment distinct from the epidermal growth factor receptor (EGFR) and erbB-2 genes was detected by reduced stringency hybridization of v-erbB to normal genomic human DNA. cDNA cloning revealed a predicted 148 kd transmembrane polypeptide with structural features identifying it as a member of the erbB family, prompting designation of the new gene as erbB-3. It was mapped to human chromosome 12q11-13 and was shown to be expressed as a 6.2 kb transcript in a variety of normal tissues of epithelial origin. Markedly elevated erbB-3 mRNA levels were demonstrated in certain human mammary tumor cell lines. These findings indicate that increased erbB-3 expression, as in the case of EGFR and erbB-2, plays a role in some human malignancies. Using erbB-3 specific antibodies (polyclonal or monoclonal), the erbB-3 protein was identified as a 180 kDa glycoprotein, gp180erbB-3. The intrinsic catalytic function of gp180erbB-3 was uncovered by its ability to autophosphorylate in vitro. Ligand-dependent signaling of its cytoplasmic domain was established employing transfectants which express a chimeric EGFR/erbB-3 protein, gp180EGFR/erbB-3. EGF induced tyrosine phosphorylation of the chimera and promoted soft agar colony formation of such transfectants. These findings, combined with the detection of constitutive tyrosine phosphorylation of gp180erbB-3 in 4 out of 12 human mammary tumor cell lines, implicate the activated erbB-3 product in the pathogenesis of some human malignancies. Thus, this invention also relates to procedures for targeting a therapeutic drug to cells having a high level of the receptor protein.
Patent EP-0563040-B1 (EP)
Inventor: FARMER PETER HARRINGTON
IPC: C08J7/04
Filed: 1990-12-20
Granted: 1995-06-14
Abstract: PCT No. PCT/US90/07554 Sec. 371 Date Jun. 7, 1993 Sec. 102(e) Date Jun. 7, 1993 PCT Filed Dec. 20, 1990.A plastic sheet, preferably of plasticized partial polyvinyl butyral, for a laminated safety glazing, having means dispersed on its surface, preferably comprising a multiplicity of spaced projections, capable of resisting adhesion to a rigid panel, such as glass, of such a glazing when the sheet is laminated to the panel, the area of the sheet surface without such dispersed means having high affinity for adhesion. The projections physically block adhesion of a dispersed area of the sheet to the panel in that the means on the sheet surface have no or weak interfacial adhesion. The multiplicity of space projections also have low or no affinity for adhesion when in blocking contact with each other or with another plasticized partial polyvinyl butyral surface and thereby increase blocking resistance.
Patent EP-0513127-B1 (EP)
Inventor: STEELE GERALD
IPC: A61K31/57
Filed: 1991-01-30
Granted: 1995-07-19
Abstract: Pressurized aerosol composition comprising a liquefied hydrofluorocarbon propellant of formula CxHyFz where x is an integer from 1 to 3, y+z=2x+2, and y and z are both at least 1; from 0.01 to 15% w/w of a particulate medicament dispersed in the liquefied hydrofluorocarbon propellant; and from 0.01 to 10% w/w of a fluorinated surfactant which is soluble in the liquefied hydrofluorocarbon propellant. The pressurized aerosol composition comprises no solvent, other than the liquefied hydrofluorocarbon propellant.
Patent EP-0468059-B1 (EP)
Inventor: INOUE TADASHI
IPC: H01J29/07
Filed: 1991-02-15
Granted: 1997-05-28
Abstract: Une mince feuille en un alliage de fer-nickel pour masques perforés comprend essentiellement entre 34 et 38 % en poids de nickel, entre 0,01 et 0,15 % en poids de silicium, entre 0,01 et 1,00 % en poids de manganèse, le pourcentage restant étant constitué de fer et des impuretés inévitables. Le pourcentage de ségrégation de silicium à la surface de la mince feuille, défini par la formule (Si concn. dans zone de ségrégation)-(Si concn. moyen)/Si concn. moyen x 100, est égal ou inférieur à 10 %. La rugosité (Ra) moyenne de la ligne médiane de la mince feuille satisfait le rapport 0,3 νm«Ra«0,7 νm. On produit cette mince feuille en dégrossissant les deux faces d'une mince feuille avec un rouleau à poncer pendant l'étape finale de laminage de la feuille jusqu'à obtenir une rugosité Ra qui satisfasse le rapport ci-dessus. La mince feuille ainsi obtenue se laisse très bien perforer par gravure et ne provoque pas de grippement pendant le recuit.
Patent EP-0526523-B1 (EP)
Inventor: WITZEMAN JONATHAN STEWART
IPC: C08G18/42
Filed: 1991-04-03
Granted: 1994-09-07
Abstract: Disclosed are thermosetting, powder coating compositions comprised of semi-crystalline polyesters and  epsilon -caprolactam-blocked bis(1-cyanato-1-methylethyl) benzene compounds which are readily curable at relatively-mild temperatures and using cure times commonly used to cure (cross-link) powder coatings. When using equivalent curing conditions, the disclosed coating compositions exhibit a higher degree of cross-linking than do combinations of amorphous polyesters and the  epsilon -caprolactam-blocked bis(1-cyanato-1-methylethyl)-benzene compounds.
Patent EP-0478766-B1 (EP)
Title: Antrieb für die schaltspindel einer absperr- oder umlenkarmatur
Inventor: SCHUTH HORST
IPC: F16K41/10
Filed: 1991-04-19
Granted: 1994-09-07
Abstract: Die Schaltspindel einer Absperr- oder Umlenkarmatur wird über einen am Kurbelzapfen (6) der Schaltspindel (2) angreifenden und am Schaltgehäuse (1) gelagerten Schalthebel (4) in ihre Schaltstellungen geschwenkt. Der bewegliche Schalthebel (4) ist mittels eines Faltenbalges gegen des Schaltgehäuse (1) hermetisch abgedichtet.
Patent EP-0502148-B1 (EP)
Inventor: BONNET DIETER
IPC: H01L21/363
Filed: 1991-09-09
Granted: 1995-05-24
Abstract: PCT No. PCT/EP91/01708 Sec. 371 Date Jun. 30, 1992 Sec. 102(e) Date Jun. 30, 1992 PCT Filed Sep. 9, 1991 PCT Pub. No. WO92/05586 PCT Pub. Date Apr. 2, 1992.A method of producing an absorber layer for solar cells by electrolytic dispersion deposition.
Patent EP-0512307-B1 (EP)
Inventor: EDMAIER FRANZ
IPC: F01P5/10
Filed: 1992-04-21
Granted: 1994-09-14
Abstract: The invention relates to a cooling system for a supercharged internal combustion engine (5) with a high-temperature and a low-temperature circuit, in which system two charge-air coolers, through which coolants at different temperatures flow, for cooling the charge air in two stages are provided. The high-temperature circuit comprises a main branch containing the internal combustion engine (5) and a high-temperature aftercooler (3) connected in series therewith. To keep down the total quantity of coolant and achieve a high degree of heat interchange while keeping the pipe configuration simple, the quantity of coolant flowing out of the secondary circuit is added to a flow of coolant leading to the internal combustion engine (5), and the entire flow of coolant flowing out of the internal combustion engine (5) is then passed to the high-temperature aftercooler (3). The quantity of coolant required in the secondary branch is diverted from the flow of coolant flowing to the internal combustion engine (5), which flows out of the high-temperature aftercooler (3) and to which quantities of coolant flowing out of the high-temperature charge-air cooler (1) and of the low-temperature charge-air cooler (22) may be added. The low-temperature circuit comprises a low-temperature aftercooler (4) with a low-temperature charge-air cooler (2) connected in series. <IMAGE>
Patent EP-0516139-B1 (EP)
Inventor: RESTREPO JOSE MANUEL
IPC: E04B5/36
Filed: 1992-05-29
Granted: 1996-05-15
Abstract: Shuttering floor slab for the two-phase construction of level concrete plates, which is thin and rectangular or polygonal in shape and contains the bending reinforcement of the final slab, used to form a level monolithic structure by assembly and embedded bonding of an upper layer to conform the final slab, characterized in that its body contains multiple parallel longitudinal passages (2) connected to its upper surface by symetrically located slots (3) placed on the longitudinal parallel axes of the passages, and having interrupted continuity, thus creating an intimate connection between the poured upper layer and the shuttering floor slab, through the material of the upper layer itself when this material enters into the longitudinal passages of the slotted floor slab through the slots in the upper face of said slab. <IMAGE>
Patent EP-0525402-B1 (EP)
Inventor: PRETZLER RUDOLF DIPL-ING
IPC: A01D34/66
Filed: 1992-06-27
Granted: 1994-12-28
Abstract: In a tractor with front-mounted lifting means, the pivot axle 8 of the lower links 9 is arranged behind and under the front axle 5, with the result that a working implement 13 shifts upwards in response to a horizontal impact and, moreover, a small front-mounting length is obtained. The pivot axle 8 is attached to a lifting-means frame 7 which is firmly connected to the front axle 5 and which is pivotable in a pivot bearing 38, together with the front axle, about its longitudinal axis 6. The lower links 9 and upper links 12 are so arranged that their points of articulation 8, 15, 14, 11 form a four-bar mechanism, the structure of which is the lifting-means frame 7 and the instantaneous centre of rotation 18 of which is either at the rear and bottom or at the front and top. <IMAGE>
Patent EP-0534095-B1 (EP)
Inventor: RIEDEL THOMAS
IPC: B65B51/10
Filed: 1992-08-01
Granted: 1995-06-28
Abstract: An apparatus for ultrasonically welding sealing seams on solvent packages is described. The apparatus has a sonotrode and an anvil (7) which is situated opposite the front end face of the sonotrode. Both the sonotrode and the anvil (7) can be moved on predetermined tracks. 
<??>So that the bearings of the entire machine are not damaged by the vibrations of the sonotrode, and therefore of the anvil as well, while at the same time guaranteeing good hygienic properties, provision has been made according to the invention for the solidly structured anvil to be axially penetrated by at least one inner bore (12, 13, 14) in which a shaft (9, 10, 11) is arranged in a contact-free manner for decoupling of the vibrations via elastic, flexible ring parts (16) while forming an annular gap, the outside diameter of the said shaft (9, 10, 11) being smaller than the inside diameter of the inner bore (12, 13, 14), and for the outside diameter of the elastic ring part (16) to be larger than the inside diameter of the inner bore. 
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Patent EP-0528261-B1 (EP)
Inventor: LANG WERNER DIPL-ING
IPC: F16L47/03
Filed: 1992-08-05
Granted: 1996-01-31
Abstract: A connecting-piece fitting can be attached by means of a saddle piece (2) to an external surface of a pipe (34), especially by welding, and in a connecting piece (4) contains a heating coil (16) for the connection of a branch line. It is proposed that the connecting piece (4) have the heating coil (16) on its inner surface (17), and that at least one centring surface (30, 33) and/or stop surface (27) be provided on the connecting piece (4) for coaxial alignment of a boring apparatus. <IMAGE>
Patent EP-0548635-B1 (EP)
Inventor: BOLZ JOACHIM DR
IPC: A61K9/16
Filed: 1992-12-05
Granted: 1995-09-06
Abstract: The invention relates to a pharmaceutical composition containing as active ingredient a compound of the formula I <IMAGE>  in which  R denotes OH or COOH or one of its pharmacologically acceptable salts, in the form of an inclusion in pre-swollen starch which can contain at least one further auxiliary.
Patent EP-0511371-B1 (EP)
Inventor: BOURJALA ROBERT
IPC: B65D6/00
Filed: 1991-11-15
Granted: 1994-07-06
Abstract: PCT No. PCT/FR91/00907 Sec. 371 Date Sep. 21, 1992 Sec. 102(e) Date Sep. 21, 1992 PCT Filed Nov. 15, 1991 PCT Pub. No. WO92/09488 PCT Pub. Date Jun. 11, 1992.A method is provided for producing plastic containers such as crates by assembling two shaped sections (7) forming opposite ends (5d and 5e) of the container along with a shaped section (1) forming the sides (5b and 5c) and the bottom (5a) thereof. Said shaped sections (7 and 1) are obtained by extruding, punching and cutting plastic material.
Patent EP-0575448-B1 (EP)
Inventor: GOTAAS EINAR
IPC: G01R31/36
Filed: 1992-03-11
Granted: 1996-06-12
Abstract: A series of accumulator cells is monitored by means of special measurement processors (s), one measurement processor to each cell. Each measurement processor (s) comprises a number of sensors for measuring parameters like temperature, acid density, acid level and pole voltage, as well as a microprocessor. The microprocessor reads measurement values and supplies these values to a common data bus (d). Each measurement processor (s) takes its power feed current from the accumulator cell to which it belongs.
Patent EP-0571756-B1 (EP)
Inventor: JACOBSEN STEPHEN
IPC: B23K26/08
Filed: 1993-04-20
Granted: 1999-09-15
Abstract: A three-dimensional circuit structure includes a plurality of elongate cylindrical substrates (4) positioned in parallel and in contact with one another. Electrical components (8) are formed on the surfaces of the substrates, along with electrical conductors (12) coupled to those components. The conductors are selectively positioned on each substrate so as to contact conductors on adjacent substrates to allow for the transfer of electrical signals between substrates. The conductor patterns on the substrates may be helical, circumferential, or longitudinal, in such a fashion that substrates may be added to or removed from the bundle so that the bundle will continue to operate as needed. The cylindrical nature of the substrates leaves gaps or channels (6) between the substrates to which cooling fluid may be supplied for cooling the circuitry.