baber/WOPTO huggingface dataset:
Patent WO-2019028246-A3 (WO)
Title: Methods of treating genetic hearing loss
Inventor: SMITH RICHARD
IPC: A61K31/7105
Filed: 2018-08-02
Abstract: In certain embodiments the present invention provides a method of treating hearing loss comprising: (a) administering a gene suppression agent that suppresses both copies of an endogenous gene causing the hearing loss; and (b) administering an exogenous wild-type allele engineered to resist suppression by the gene suppression agent. The present invention provides in certain embodiments a method of treating a genetic hearing loss (GHL) in a patient in need thereof comprising: (a) identifying a mutation in a GHL-causing gene, wherein the mutation causes GHL in the patient; and (b) administering to the patient a pharmaceutical composition comprising a therapeutic miRNA and a pharmaceutically acceptable carrier, wherein the GHL therapeutic miRNA is of 18 to 25 nucleotides in length and knocks-down the GHL-causing gene function at a higher level than it knocks-down gene function in a corresponding wild-type gene.
Patent WO-2019051274-A3 (WO)
Title: Devices for treating lung tumors
Inventor: PANESCU DORIN
IPC: A61B18/14
Filed: 2018-09-07
Abstract: An apparatus (150) for ablating a tumor in a lung including: an elongate shaft (149); an obturator (152) positioned at a distal region of the elongate shaft, a suction lumen (166) extending through the elongate shaft and exiting the shaft distal to the obturator, wherein the suction lumen is configured to remove air or fluid from the portion of the lung, an ablation catheter delivery lumen (153) extending through the elongate shaft and exiting the shaft distal to the obturator, and an ablation catheter (155, 154) comprising an RF electrode (156, 157).
Patent WO-2019161145-A3 (WO)
Title: Improved management of corn through semi-dwarf systems
Inventor: BARTEN TY J
IPC: A01H1/04
Filed: 2019-02-15
Abstract: Methods for providing compositions to corn fields prior to harvesting are provided herein. These methods provide an extended time period for the use of lower height or standard height farm equipment in-season in corn fields, while reducing the risk of damage to the corn plants. These methods also allow for late season access with lower height or standard height farm equipment, while reducing the risk of damage to the corn plants.
Patent WO-2019222718-A3 (WO)
Title: Three-dimensional model of particle interactions applying two-dimensional feynman diagrams
Inventor: ZORNES DAVID
IPC: H05H7/04
Filed: 2019-05-17
Abstract: This invention teaches One "common" electrodynamic (interaction of electric currents with magnetic fields or other electric currents) CYCLOID curve (E-cycloid) must organize and unite random pathways from other curves into ONE tessellated progression of E-cycloid curves in three-dimensional arrays, ring-Linked into entangled pathways of how energy waves cycle between particles and energy. The fine-structure constant "a" is the single parameter of this model, measuring strength of the force between two electrons, because there are no unpaired elements in spacetime. At a molecular scale to avoid atomic constructive interference, at least one of a regular hexagon side in the first stack of graphene is positioned by locating its side midpoint to the centerpoint "holes"of the regular hexagon in the second stack, which provides two stacks perpendicular to each other, suspending one planar 2D graphene sheet stack within a second graphene sheet stack.
Patent WO-2021081471-A3 (WO)
Inventor: BEVIRT JOEBEN
IPC: G09B9/14
Filed: 2020-10-25
Abstract: A method and system for modeling aerodynamic interactions in complex eVTOL configurations for realtime flight simulations and hardware testing which includes decomposing the aircraft into aerodynamic subcomponents, wherein the interactions between these components are handled by flow simulations of the surrounding fluid, which may be Euler flow CFD simulations. A computer generated simulation can be used to analyze the fluid flow and pressures, the forces delivered by an aircraft into the fluid and the forces onto the aircraft from the fluid, to determine the position and attitude of the aircraft, and other aspects. The system may be used as a flight simulator for pilot training in a realtime environment. The system may be used to support component testing using an interface to those components, such as flight electronics and actuators, to test the components in high fidelity simulations of actual flight demands on those components. The system may also be used to support design analysis in non-realtime to run numerous simulations on different designs and to provide comparative output.
Patent WO-2021092489-A3 (WO)
Inventor: CHAN JAMES
IPC: G01N21/65
Filed: 2020-11-06
Abstract: A method for determining if a tissue is ganglionic is provided. The method comprises a) generating at least one hyperspectral Raman image of a tissue from a region of interest in a tissue suspected to contain ganglion cells that was optionally identified by a method comprising autofluorescence (AF) and Second Harmonic generation (SHG) imaging of the tissue; and b) analyzing any of the images for one or more of the following: i) optical excitation; ii) chemical information or emission spectra; or iii) AF, SHG, and/or Raman signatures, wherein the analysis provides indicators that the region of interest is either ganglionic or non-ganglionic. A system for analysis of  in vivo  tissue or ex vivo tissue samples including a multiphoton autofluorescence microscope, a Second Harmonic Generation microscope, and a hyperspectral Raman microscope in operative communication is also provided.
Patent WO-2021242629-A3 (WO)
Title: A heat trace characterization and control method and system
Inventor: KUSTER TRAVIS
IPC: H05B3/00
Filed: 2021-05-21
Abstract: The present invention involves calibrating a control system to enable resistance-based control of a heat tracing circuit, that includes characterizing a piece of heat trace to determine a relationship between resistance and temperature, allowing for more precise control. Also described are different methods for practical resistance-based control of a heat trace system. Further described are several methods to monitor heat trace: including methods to enhance monitoring capabilities using a system operating model; comparison to historical operating data; and inclusion of information from external sources. Also provided is a method by which a piece of heat trace of unknown length and power factor can be controlled using the resistance-based method when other system information is available.
Patent WO-2021252201-A3 (WO)
Title: 3d reconstruction using wide-angle imaging devices
Inventor: FOX-ROBERTS PATRICK
IPC: G06T7/579
Filed: 2021-05-27
Abstract: The pose of a wide-angle image is determined by dewarping regions of the wide-angle image (602), determining estimated poses of the dewarped regions of the wide-angle image (604, 614) and deriving a pose of the wide-angle image from the estimated poses of the of the dewarped regions (616, 618). The estimated poses of the dewarped regions may be determined by comparing features in the dewarped regions with features in prior dewarped regions from one or more prior wide-angle images, as well as by comparing features in the dewarped regions with features in a point cloud.
Patent WO-2022061110-A3 (WO)
Title: Réfrigérateur
Inventor: MAASKANT YANNICK
IPC: F25B5/00
Filed: 2021-09-17
Abstract: Un réfrigérateur modulaire comprend une pluralité de modules avec au moins un module d'unité de refroidissement et au moins un module de réfrigération. Le ou les modules d'unité de refroidissement et le ou les modules de réfrigération sont construits indépendamment et fixés l'un à l'autre. Le ou les modules de réfrigération peuvent comprendre au moins un premier module de réfrigération et un second module de réfrigération. Le ou les modules d'unité de refroidissement peuvent être un module d'unité de refroidissement commun pour fournir sélectivement un fluide frigorigène aux premier et second modules de réfrigération.
Patent WO-2022066597-A3 (WO)
Inventor: RUDE RICHARD
IPC: B65D47/04
Filed: 2021-09-21
Abstract: An aerating bottle stopper (10) comprises a stopper component (12) and an aerator component (11), which is releasably attached to the bottom of the stopper component by at least one break-away connector (13). During the bottling of the beverage, the aerating bottle stopper is inserted into the neck of the bottle to seal it. In order to open the bottle, the stopper component is removed causing the break-away connector to separate, releasing the aerator component so that it remains in the neck of the bottle. Multiple flow channels (15) pass through the aerator component. When the beverage is poured through the bottle neck, its flow through the flow channels becomes turbulent so as to cause air to mix with the beverage and aerate it.
Patent WO-2021237234-A3 (WO)
Title: Dynamic switching between carrier aggregation and multi-connectivity
Inventor: YANG MING
IPC: H04W36/00
Filed: 2021-05-05
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may transmit a first communication that includes information to facilitate selection and/or switching of carrier aggregation or multi-connectivity for a first cell group and a second cell group. The UE may receive, based at least in part on transmitting the first communication, a second communication that configures and/or switches carrier aggregation or multi-connectivity for the first cell group and the second cell group. Numerous other aspects are provided.
Patent WO-2022178110-A3 (WO)
Title: Dnase 1-like 2 engineered for manufacturing and use in therapy
Inventor: FUCHS TOBIAS A
IPC: C12N5/10
Filed: 2022-02-17
Abstract: The present disclosure provides a D1L2 enzyme lacking a proline-rich domain (PRD) and/or lacking the C -terminal Arg residue, which is efficiently produced in microbial expression systems such as  Pichia pastoris  , and has high activity for degrading chromatin at acidic pH. The present disclosure provides methods of the production and use of the D1L2 enzyme in therapy.
Patent WO-2022204564-A3 (WO)
Title: Methods and compositions for t-cell coculture potency assays and use with cell therapy products
Inventor: SIMPSON-ABELSON MICHELLE
IPC: C12N5/0783
Filed: 2022-03-25
Abstract: The present invention provides novel processes, compositions, and methods for analyzing or assaying the potency and/or functionality of tumor infiltrating lymphocyte (TIL) products for use in therapy, including human cancer therapy, and analyzing or assaying the potency and/or functionality of other polyclonal products, such as marrow infiltrating lymphocyte (MIL) and peripheral blood lymphocyte (PBL) products. Compositions, methods, and kits for preparing and treating cancer using TIL, MIL, and PBL products are also provided.
Patent WO-2022216552-A3 (WO)
Title: Novel hepatoselective polyadenylating polymerases inhibitors and their method of use
Inventor: DU YANMING
IPC: C07D401/14
Filed: 2022-04-01
Abstract: Described herein are hepatoselective inhibitors of PAPD 5 and 7 having a disease-modifying action in the treatment of diseases associated with PAPD 5 and 7 that include disease such as hepatitis B and liver cancer. Compositions comprising same; and methods of making and using same are also described herein.
Patent AT-515116-A4 (AT)
Title: Bildschirmgerät
IPC: G07F17/32
Filed: 2014-01-13
Abstract: Bildschlrmgerät, vorzugsweise Spiel- und/oder Unterhaltungsautomat, mit einem Gerltegehäuse, das eine Gehäusetür zum Öffnen und Schließen des Gerätegehäuses aufweist, wobei die Gehäusetür für zumindest einen Bildschirm einen Rahmen bildet, dessen Rahmenschenkelden zumindest einen Bildschirm einfassen und einen Rahmenausschnitt begrenzen, wobeider Rahmen einen modularen Aufbau besitzt und aus mehreren Rahmentelien variabel in unterschiedlichen Konfigurationen, in denen der Rahmen unterschiedlich viele und/oder unterschiedlich große Rahmenausschnitte besitzt, zusammensetzbar Ist.
Patent AT-504652-A4 (AT)
Title: Burning chamber for boiler with heated solid fuel, has multiple burning chamber bricks which are covered by base plate , where base plate has multiple combustion bricks
IPC: F23M5/02
Filed: 2007-03-29
Abstract: The burning chamber (2) has multiple burning chamber bricks which are covered by a base plate (4). The base plate has multiple combustion bricks. The burning chamber has a process expansion in flow direction of combustion gas. The combustion bricks lie on a frame connected firmly with a furnace wall of the boiler (1).
Patent SU-1670882-A4 (SU)
Title: Device for trimming metallic articles
Inventor: SALOMATIN V M
IPC: B23D67/06
Filed: 1988-12-15
Granted: 1994-02-28
Abstract: FIELD: machining. SUBSTANCE: device for trimming has main holder 1, auxiliary holder 3 mounted on cylindrical surface 2 of holder 1, compensating ring 4 interposed between holders 1 and 3. Holders 1 and 3 have two roes of openings 9 and 7 for receiving tools. Auxiliary holder 3 is rotatably mounted about main holder 1 with the aid of fly wheel 13. Openings 7 should be offset relative to openings 9 by rotating flywheel 13 so that the tools of both holders come in contact with workpiece 11 to be machined for circumferential pitches of windows of the workpiece are not in register in angle. EFFECT: widened operating capabilities. 3 dwg
Patent EP-1194818-A4 (EP)
Title: An operator interface for a skid steer loader
Inventor: ROSSOW SCOTT R
IPC: G05B23/02
Filed: 2000-05-24
Abstract: The present invention is directed to a user interface to a computer-based control system (50) for controlling hydraulic and/or electro-mechanical actuators, or electrical actuators (64, 66, 67) on a power machine (10). The user interface provides one or more features to increase functionality or usefulness in the user interface.
Patent EP-1237101-A4 (EP)
Inventor: NISHIYAMA KOHEI
IPC: G06Q10/00
Filed: 2000-08-25
Abstract: L'invention concerne un système visant à proposer des produits à la clientèle via un réseau, et à recueillir les desiderata de la clientèle en matière de spécifications liées aux produits pour déterminer les spécifications définitives des produits. Le système permet ainsi de recueillir les éléments constitutifs de la demande relative aux produits pour déterminer ces produits avec un minimum de risque, moyennant quoi la clientèle peut recevoir des produits dont les spécifications répondent à son attente, à un prix relativement peu élevé.
Patent EP-1273398-A4 (EP)
Title: Unit set for robot
Inventor: KAZAMI KEIICHI
IPC: B25J17/00
Filed: 2000-08-25
Abstract: A unit for constructing a robot with units, wherein a joint unit comprising joint means is stored in a joint casing having a surface profile of a dice-like cube, uniaxial cylindrical body, or orthogonal dual-axis cylinder-like cubic with the joint means positioned at equal intervals, the joint means comprises N positioning projections disposed about the center axis thereof at equal intervals and equal angles and N connecting screw holes respectively disposed at positions rotated from these projections by 360 °/2N about the center axis thereof, and a zero-degree joint power transmission unit converts, before transmission, the rotation of the joint unit rotated, by itself, relative to an input joint fixed shaft fixed to the joint casing to the rotation of an output rotating shaft disposed a joint-unit separation-distance away therefrom.
Patent EP-1152239-A4 (EP)
Title: Biosensor, method of forming thin-film electrode, and method and apparatus for quantitative determination
Inventor: MIYAZAKI SHOJI
IPC: G01N27/327
Filed: 2000-11-14
Abstract: A biosensor comprises, as shown in chart (1), a substrate (1); a conductor layer (2) consisting of precious metal such as gold and palladium or conductor such as carbon; slits (3a, 3b) parallel to the sides of the substrate; slits (4a, 4b) perpendicular to the sides of the substrate; a measuring electrode (5); a counter electrode (6); a detection electrode (7); a spacer (8) covering the measuring electrode (5), the counter electrode (6) and the detection electrode (7) on the substrate (1); a rectangular cut (9) forming a channel through which a sample is supplied; an entrance (9a) to the channel; a reagent layer (12) formed of an enzyme-containing reagent applied to the measuring electrode (5), the counter electrode (6) and the detection electrode (7) which are exposed through the cut (9) in the spacer (8); and a cover (13) over the spacer (8). The biosensor can be provided by a simple technique, and it is of precision and reliability because a uniform layer of reagent, regardless of the composition, covers the electrodes.
Patent EP-1168650-A4 (EP)
Title: High-frequency switch, high-frequency switch module, and wireless communication device
Inventor: KEMMOCHI SHIGERU
IPC: H04B1/50
Filed: 2000-12-28
Abstract: A high-frequency switch circuit common to a plurality of frequency bands comprises a first high-frequency switch (SW2) connected to a high-frequency signal input (10) and output terminals and adapted to pass transmission signals of a first or a second frequency band and block received signals of the first and second frequency band; and a demultiplexer has a first high-frequency circuit which consists of a first phaseshifter (3) connected to a first terminal and a first bandpass filter (5) succeeding to the first phaseshifter (3), and a second high- frequency circuit which consists of a second phaseshifter (4) connected to the first terminal and a second bandpass filter (6) succeeding to the second phaseshifter (4). The transmission line in the first phaseshifter (3) has a line length such that the input impedance of the first high-frequency circuit is substantially open in the pass band of the second bandpass filter (6), whereas the transmission line in the second phaseshifter (4) has a line length such that the input impedance of the second high-frequency circuit is substantially open in the pass band of the first bandpass filter (5). Thus, the high-frequency switch circuit passes one of the received signals of the first and second frequency bands and blocks the other.
Patent EP-1285261-A4 (EP)
Title: Field effect transistor device for ultra-fast nucleic acid sequencing
Inventor: SAUER JON
IPC: C12Q1/68
Filed: 2001-04-24
Abstract: A system for facilitating movement of a polymer, comprising: a semiconductor device having a first end defining a first opening, a second end defining a second opening and a channel extending between the openings through which the polymer can pass; a first electrode positioned proximate to the first end; a second electrode positioned proximate to the second end; and a power source connected to the first and the second electrodes, the power source operable to provide a voltage to induce an electric field such that the polymer is caused to migrate through the channel.
Patent EP-1293297-A4 (EP)
Title: Polishing pad
Inventor: KOMUKAI TAKUJI
IPC: B24B37/22
Filed: 2001-06-18
Abstract: A polishing pad includes a pad body; and a transparent window integrally formed in the pad body. The window is formed of a material which is more susceptible to abrasion than a material of the pad body. The pad body has a plurality of grooves formed in a surface thereof, and the window has no grooves in a surface thereof. A surface of the window is recessed with respect to a surface of the pad . The polishing pad prevents a slurry from settling on the window so as to improve the detection precision of the polishing rate. Furthermore, the polishing pad prevents the window from gradually projecting with respect to the pad body by dressing during polishing so as to substantially eliminate adverse effect on the polishing characteristic. <IMAGE>
Patent EP-1374458-A4 (EP)
Title: Method and apparatus for implementing a mac coprocessor in a communications system
Inventor: BOURLAS YAIR
IPC: H04L12/28
Filed: 2002-03-04
Abstract: Disclosed is a novel method and system for efficiently synchronizing, transmitting, and receiving data between a base station and a plurality of customer premises. A MAC coprocessor (MCP) (402) is implemented, which works in conjunction with the MAC (410) in order to produce a robust, high throughput communication system. The MAC coprocessor (402) performs many of the tasks typically performed by prior art MAC's, including: during a downlink, storing a data frame, sorting the data frame according to modulation type or other criteria, determining when the data frame is full, and appending a set of CPE settings to the data frame. During an uplink, the MAC coprocessor (402) receives all data and routes the data either to the MAC (410) or a network backhaul. A MAC coprocessor (402) may be used in both the base station and Customer Premises. In both the downlink and uplink processes, having a MAC coprocessor working in conjunction with the MAC may significantly increase the communication system's throughput.
Patent EP-1420091-A4 (EP)
Inventor: KAWAMURA ATSUSHI
IPC: D01F9/32
Filed: 2002-06-11
Abstract: L'invention concerne un appareil de production et un procédé de production de fibres de carbone, capables d'une opération continue et de réduire les coûts avec une opérabilité dans un procédé de chauffe amélioré en fournissant positivement des parties de connexion présentant un mécanisme simple et une capacité de procédé élevée. L'appareil de production comprend une paire d'appareils (12) de préhension de fils recouvrant les fils de fibres précurseurs à connecter l'un sur l'autre et agrippant les extrémités recouvertes et une unité de traitement de fluide entre la paire d'appareils (12) de préhension afin de lancer des jets de plusieurs rangs de fluides le long de la direction de longueur pour lier les fils. Plusieurs zones (11b) de manipulation de filetage discontinu des fils de fibres précurseurs dans les zones de jet de fluide possédant des orifices (11a) de jet de fluide de l'unité de traitement de fluide sont disposées à des intervalles (S) spécifiés.
Patent EP-1464414-A4 (EP)
Title: Method and facility for separating and recovering steel pipe and covering resin in resin-covered steel pipe
Inventor: MATSUMOTO TATSUO
IPC: B29B17/04
Filed: 2002-11-05
Abstract: There are provided a method and a facility for separating and recovering a steel pipe and a covering resin in a resin-covered steel pipe, which do not produce cuttings of the steel pipe and which make it possible to continuously operate the facility. The method comprises the steps of using a cut line forming means installed forwardly of the position that a high frequency induction coil passes, so as to form a cut line extending from the surface of the resin-covered steel pipe toward the steel pipe, deep enough to reach the surface of the steel pipe from the surface of the covering resin, throughout the length of the resin-covered steel pipe, circumferentially dividing the covering resin into at least two parts, heating the steel pipe by high frequency induction heating, in the position of a separating device disposed at a suitable position immediately after the passage of the position of the high frequency induction coil, to the extent the boundary between the covering resin and the steel pipe assumes the state for the release of the covering resin from the steel pipe, and cutting each covering resin into at least two parts along the cut line and toward the outside of the steel pipe by the separating device while releasing and separating it from the steel pipe.
Patent EP-1475854-A4 (EP)
Title: Battery terminal structure
Inventor: ISHII YOSHIZUMI
IPC: H01M50/574
Filed: 2002-12-24
Abstract: A battery terminal structure of a battery (1) having a terminal part (6) projected from the upper surface of a battery case (2) installed at the top end of a pole (5) upwardly extended from a pole plate group (3) stored in the battery case (2), wherein the pole (5) is formed in a double tube structure having a core bar part (9) fitted into an outer tube part (8) so as to be shortened by a load from an upper side, whereby, when a large load acts on the terminal part (6) from the upper side, the pole (5) is shortened so that the downward displacement of the terminal part (6) can be produced rather easily.