baber/WOPTO huggingface dataset:
Patent EP-3589754-A1 (EP)
Inventor: HEGDE PRITI
IPC: C12Q1/6886
Filed: 2018-03-01
Abstract: The present invention provides diagnostic methods, therapeutic methods, and compositions for the treatment of cancer (e.g., kidney cancer (e.g., renal cell carcinoma (RCC)), lung cancer (e.g., non-small cell lung cancer (NSCLC)), bladder cancer (e.g., urothelial bladder cancer (UBC)), liver cancer (e.g., hepatocellular carcinoma (HCC)), ovarian cancer, or breast cancer (e.g., triple-negative breast cancer (TNBC))). The invention is based, at least in part, on the discovery that expression levels of one or more biomarkers described herein in a sample from an individual having cancer can be used in methods of predicting the therapeutic efficacy of treatment with a VEGF antagonist (e.g., an anti-VEGF antibody, (e.g., bevacizumab) or a VEGFR inhibitor (e.g., a multi-targeted tyrosine kinase inhibitor (e.g., sunitinib, axitinib, pazopanib, or cabozantinib))) and a PD-L1 axis binding antagonist (e.g., a PD-L1 binding antagonist (e.g., anti-PD-L1 antibody, e.g., atezolizumab (MPDL3280A)) or a PD-1 binding antagonist (e.g., anti-PD-1 antibody)), or with an angiogenesis inhibitor (e.g., a VEGF antagonist (e.g., a VEGFR inhibitor, (e.g., a multi-targeted tyrosine kinase inhibitor (e.g., sunitinib, axitinib, pazopanib, or cabozantinib)))).
Patent EP-3573710-A1 (EP)
Inventor: TISCHENDORF BRAD C
IPC: H01L23/10
Filed: 2018-01-19
Abstract: In some examples, an implantable medical device (IMD) comprises an electrochemical cell compartment that may define a barrier between an inside of the compartment and an outside of the compartment. The IMD may include an electrically conducting pad. The IMD may comprise an electrically conducting pin coupled to the pad. The pad may include top and bottom sides. The pin may extend from the bottom side of the pad. The pad may be positioned outside of the compartment and the pin may extend through an aperture in the compartment from inside the compartment to pad positioned outside of the electrochemical cell compartment. The IMD may include an electrically insulating material surrounding the aperture and between the bottom side of the pad and the compartment. The insulating material may insulate the pad from the barrier and form a seal between the inside of the compartment and the outside of the compartment.
Patent EP-3603259-A1 (EP)
Inventor: IYER LAKSHMI R
IPC: H04W72/04
Filed: 2018-03-20
Abstract: It is recognized herein that, in some cases, URLLC transmissions may preempt a scheduled eMBB transmission. Thus, in accordance with one embodiment, resources are allocated for URLLC data transmission in a manner that minimally impacts eMBB data transmissions. In an example code block groups are configured for efficient multi-bit A/N feedback. Multi-bit A/N methods are disclosed with and without explicit resource allocation. Various preemption mechanisms are also described herein including, for example, puncturing, dropping the tail end of a transport block, and increasing rate matching.
Patent EP-3607427-A1 (EP)
Inventor: KRUSE DENVER WAYNE
IPC: G06F3/14
Filed: 2018-04-02
Abstract: A display system comprises a plurality of displays each comprising an array of light-emitting elements to display a corresponding message, a primary controller that controls the array of light-emitting elements of each display to control the content of each message, a communication network to transmit control signals from the primary controller to the displays, a remote manager in communication with the primary controller via a primary manager communication link, and a redundant controller configured and able to control the array of light-emitting elements of each display to control the content of each message if it is determined that there is a malfunction of the primary controller, an interruption in the communication network between the primary controller and at least one of the displays, or an interruption in the primary communication link.
Patent EP-3602076-A1 (EP)
Title: Labels, receptacles, systems, and methods for automatic sample processing
Inventor: SILBERT ROLF
IPC: G01N35/00
Filed: 2018-03-30
Abstract: A sample receptacle can be used for ordering assays to be performed by an automatic sample processing instrument. The sample receptacle can include a body defining a chamber for containing a sample and a label. The label can include discrete areas configured to be altered from a first assay order state to a second assay order state. Each discrete area has a known association with a different assay. The label can also include assay-identifying indicia indicating the respective assay associated with a respective discrete area. A method of processing a sample in a receptacle having one or more assay order states can include automatically determining assay order states of the discrete areas and performing an assay on the sample, using the automatic sample processing instruments, based on the determined assay order states of the discrete areas.
Patent EP-3619718-A1 (EP)
Inventor: LASSERRE GILLES HENRI
IPC: G16H20/10
Filed: 2018-05-04
Abstract: The present invention relates to a system and method for building and using a compartmentalised multifactorial database containing personal data relating to health, family, food and eduction, as well as to related activities and the corresponding environment, and uses thereof. In particular, the present invention relates to a clinical artificial intelligence system operating with a medical decision support computer system cooperating with a mobile health intelligent personal assistant, in communication with a network of biomedical devices and other connected objects collecting information on an element interacting with one or more people and/or their family members from a given population and with health professionals. The clinical artificial intelligence system operates, for example, with a computer system for obtaining data relating to one or more biotopes. The invention also relates to a system and method for managing and getting value from a wealth of private and public intimate personal data.
Patent EP-3548677-A1 (EP)
Title: Verfahren zur sanierung und zum neubau von feuchträumen und sanierungssatz hierfür
Inventor: WEDI STEPHAN
IPC: E04F15/18
Filed: 2018-04-26
Abstract: Die Erfindung betrifft ein Verfahren zur Sanierung und zum Neubau von Feuchträumen, bei dem großformatige Plattenmodule (10, 10') an einer Wand (15) und/oder einem Boden (14) und/oder einer Raumdecke des Feuchtraums eingebracht werden. Das Verfahren zur Sanierung umfasst folgende Verfahrensschritte: a) Bereitstellen von Plattenmodulen (10; 10') welche eine wasserundurchlässige Beschichtung oder einen wasserundurchlässigen Kern (11) umfassen, zum Einbau in den Feuchtraum; b) Festlegen einer Einbauposition eines Plattenmoduls (10; 10'); c) Anbringen wenigstens eines wasserresistenter Abdichtband-Abschnittes (16; 17) in einer eine Außenkontur (20) des Plattenmoduls (10; 10') abbildenden Position; d) Aufbringen eines wasserresistenten Dichtklebers auf den wenigstens einen Abdichtband-Abschnitt (16; 17), derart, dass der wasserdichte Dichtkleber im fertig montierten Zustand die Randbereiche zweier benachbarter Plattenmodule (10; 10') durchgängig unterfüttert; e) Anpressen eines ersten Plattenmodul (10; 10') auf einen ersten Teilbereich des Dichtkleber und ein sich an das erste Plattenmodul (10, 10') anschließendes zweites Plattenmodul (10; 10') in einer Position, in der die beiden aneinandergrenzenden Seitenbereiche der Plattenmodule (10; 10') vollständig mit Dichtkleber unterfüttert sind, so dass zwischen dem ersten und dem zweiten Plattenmodul (10; 10') eine Dichtstelle (23) herstellbar ist, die verhindert, dass durch eine zwischen den Plattenmodulen (10; 10') ausgebildete Fuge (24) Feuchtigkeit in die Wand (15), den Boden (14) oder die Raumdecke gelangen kann. Die Erfindung betrifft weiterhin einen Sanierungssatz zur Durchführung des erfindungsgemäßen Abdichtverfahrens.
Patent EP-3638116-A1 (EP)
Inventor: SCHNEIDER STEFAN
IPC: G01N33/497
Filed: 2018-06-01
Abstract: Die Erfindung betrifft ein Mundstück (100) für eine Vorrichtung (200) zur Messung von Analyten in Ausatemluft, wobei das Mundstück (100) einen Gaspfad (130) für eine Leitung von Ausatemluft zur Vorrichtung (200) aufweist, wobei dass das Mundstück (100) eine Folie (140) umfasst, wobei die Folie (140) derart angeordnet ist, dass sie die Leitung der Ausatemluft durch den Gaspfad (130) blockiert. Ferner betrifft die Erfindung ein System (1000) und ein zugehöriges Verfahren (500) zur Messung von Analyten in Ausatemluft, umfassend ein solches Mundstück (100) und eine Vorrichtung (200) zur Messung von Analyten in Ausatemluft, wobei das Mundstück (100) mit der Vorrichtung (200) lösbar verbindbar ist, wobei die Vorrichtung (200) einen Drucksensor (220) und vorzugsweise eine Pumpe (210) zum Pumpen von Luft über das verbundene Mundstück (100) umfasst und dazu eingerichtet ist, die Vorrichtung (200) für eine Messung vorgegebener Analyten in der Ausatemluft freizugeben, wenn ein über den Drucksensor (220) gemessener Druckverlauf ein oder mehrere vorgegebene Bedingungen erfüllt.
Patent EP-3568018-A1 (EP)
Inventor: VORONKOV MICHAEL
IPC: A61K31/197
Filed: 2018-01-12
Abstract: The present invention provides compounds useful in treating or preventing inflammation, acne, bacterial conditions and promoting the appearance of healthy skin and compositions including these compounds.
Patent EP-3573638-A1 (EP)
Inventor: MARTINEZ IGNACIO
IPC: A61P31/04
Filed: 2018-01-24
Abstract: Provided herein are methods and compositions useful for human health, e.g., for targeting one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the modulation resulting in a decrease in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the modulating agent described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in humans.
Patent EP-3673002-A1 (EP)
Inventor: PIESTERT FREDERIK
IPC: C08L63/00
Filed: 2018-08-20
Abstract: The invention relates to the use of a branched polyester having an average of at least 2.8 terminal groups as additive for a curable pre-polymer composition, wherein the branched polyester acts as de-foaming agent.
Patent EP-3662238-A1 (EP)
Inventor: LOMMATZSCH THOMAS
IPC: G01J5/02
Filed: 2018-07-10
Abstract: Disclosed is an optical detector device comprising a housing with a projecting neck that is closed towards the outside by a light-permeable disk, underneath which at least one optical waveguide is arranged that tapers in the direction of an optical sensor, further comprising an optical waveguide assembly (18) having a plurality of optical waveguides which are retained in the neck (8) by a holding mechanism (25).
Patent EP-3590781-A1 (EP)
Inventor: ISHII TAKAYA
IPC: B60W30/00
Filed: 2018-02-21
Abstract: The present invention supports appropriate switching from an automatic travel mode to a manual travel mode. A moving object travel support apparatus 1 according to the present invention is a moving object travel support apparatus capable of switching between a manual travel mode and an automatic travel mode, and includes: a travel mode determination unit 121 that determines which travel mode is to be selected out of a manual travel mode and an automatic travel mode; a scheduled switching point decision unit 122 that decides a scheduled switching point at which the automatic travel mode is switched to the manual travel mode in a case where the travel mode determination unit selects the manual travel mode; and a travel control details decision unit 124 that decides travel control details at the time of travel in the automatic travel mode up to the scheduled switching point on the basis of a condition of a predetermined manual travel zone including the scheduled switching point out of the manual travel zones on which travel in the selected manual travel mode is scheduled.
Patent EP-3597341-A1 (EP)
Inventor: YUMOTO Ryouhei
IPC: H01L23/12
Filed: 2018-02-28
Abstract: A method for producing a bonded body includes: a laminating step of forming a laminated body in which a first member and a second member are temporarily bonded to each other by providing a temporary bonding material including an organic material on at least one of a bonding surface of the first member and a bonding surface of the second member; and a bonding step of pressurizing and heating the laminated body in a laminating direction and bonding the first member and the second member to each other. In the bonding step, during a temperature increase process of heating the laminated body up to a predetermined bonding temperature, at least a pressurization load P2 at a decomposition temperature T<sub>D</sub>of the organic material included in the temporary bonding material is lower than a pressurization load P1 at the bonding temperature.
Patent EP-3673029-A1 (EP)
Title: Compositions with polyaziridine crosslinkers for treating subterranean formations
Inventor: HILFIGER MATTHEW GARY
IPC: C08L35/00
Filed: 2018-08-21
Abstract: The present application provides a composition containing a maleic anhydride copolymer, a polyaziridine crosslinker, optionally an additional crosslinking agent such as an amine crosslinker, and optionally a gel time control agent. Methods of using the composition to treat a subterranean formation are also provided.
Patent EP-3673087-A1 (EP)
Inventor: COLOMER DURAN RAMON
IPC: C14C3/16
Filed: 2018-08-22
Abstract: The present invention relates to a method for tanning an animal skin comprising the steps of: (a) placing said animal skin in contact with a first tanning bath comprising at least one dialdehyde with the general formula (I) 0=CH- (CH) n -HC=0 (I), where n is 0 or an integer in the range 1-8, said tanning bath having a pH in the range 1-5; (b) bringing the pH of the tanning bath to a pH above 5 and below 8; (c) repeating one or more times said steps (a) and (b) on said skin coming from said step (b) using a second or further tanning bath; said first, second and further tanning bath being substantially free from surfactants. The method according to the invention allows to reduce the quantity of visible superficial defects on the final leather. The method according to the invention also allows to obtain a leather with high thickness and with high area yield.
Patent EP-3676288-A1 (EP)
Inventor: MACOOL DANIEL JOSEPH
IPC: C12P7/06
Filed: 2018-08-21
Abstract: Described are compositions and methods relating to modified yeast expressing exogenous, or increased amounts, of glucose-specific, ATP-mediated transporters. The modified yeast produces an increased amount of ethanol compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates.
Patent EP-3676073-A1 (EP)
Inventor: RE EMILIO
IPC: B29L31/00
Filed: 2018-08-30
Abstract: An apparatus (1) for blow molding plastic containers, particularly bottles, comprising a blow molding carousel (10), which can rotate about a main rotation axis (100) and is functionally connected, at a first transfer station and at a second transfer station (20, 30), to a line (21) for feeding the preforms (50) and to a line (22) for unloading the bottles (51), the blow molding carousel (10) supporting, at its peripheral region (11), a plurality of forming units (12) arranged around the main rotation axis (100), each forming unit (12) comprising a mold (13) that defines a first and a second forming cavity (14a, 14b) and is formed by two half-mold parts (13a, 13b), which can move with respect to each other to pass between an open position for feeding the preforms (50) and for unloading the bottles (51) and a closed position, in which it defines at least one forming cavity (14a, 14b).
Patent EP-3603600-A1 (EP)
Inventor: GALVEZ CAMPOS JOSÉ LUIS
IPC: A61H1/02
Filed: 2018-03-27
Abstract: The invention relates to an apparatus for exercising the lower limbs of the human body which, from a motor unit and by means of rods, transmits a reciprocating movement to a pair of supports on which rest the feet of a user. The motor unit is housed in a greased closed compartment seated on a rubber seat plate secured to the base of the apparatus. The drive shaft is a worm that meshes with a gear wheel joined eccentrically to a set of rods that is secured to one of the two arms (9) of the apparatus so as to rotate about a stationary central shaft (12), and which are secured by securing shafts (11), located at the ends, to respective supports (10). Both the central shaft (12) and the securing shafts (11) of each arm (9) have hubs with radial bearings and are seated on respective axial bearings.
Patent EP-3599977-A1 (EP)
Title: Medical tool positioning devices, systems, and methods of use and manufacture
Inventor: SCHAER ALAN
IPC: A61B1/00
Filed: 2018-01-24
Abstract: Medical tool positioning and control devices, systems, and methods. Handle assemblies that allow a steerable shaft to be steered, while allowing the separate movement of a medical tool. The handle assemblies can allow for rotation and axial movement of the medical tool, and optionally with an actuator disposed distal to a second actuator that controls steering of the steerable shaft.
Patent EP-3700826-A1 (EP)
Inventor: AUSLOOS VERA
IPC: B65D85/68
Filed: 2018-09-20
Abstract: L'invention concerne un emballage de balai d'essuie-glace (10) pour un balai d'essuie-glace (12) doté d'un adaptateur de fixation (14) pour un bras d'essuie-glace. Ledit emballage de balai d'essuie-glace comprend un suremballage (16) de structure oblongue qui présente une extension longitudinale (20) avec une ouverture de prélèvement (23) pouvant être fermée, ménagée sur une face frontale (22). Selon l'invention, une autre ouverture (26) se situe dans la zone destinée à l'adaptateur de fixation (14), le long de l'extension longitudinale (20).
Patent EP-3613588-A1 (EP)
Inventor: NODA HIROAKI
IPC: B32B5/16
Filed: 2018-04-17
Abstract: A laminate comprising a plastic substrate (A); a hardened organic polymer layer (B) provided on a surface of the plastic substrate (A) and having a storage elastic modulus of from 0.01 to 5 GPa and tanδ of from 0.1 to 2.0 at 25°C which are measured at a temperature elevating rate of 2°C/min by a dynamic viscoelasticity test stipulated in JIS K 7244; an organic/inorganic composite layer (C) provided on a surface of the hardened organic polymer layer (B) and containing covalently bound organic polymer and metal oxide nanoparticles; and an inorganic layer (D) provided on a surface of the organic/inorganic composite layer (C) and comprising secondary particles of ceramic or metal.
Patent EP-3698148-A1 (EP)
Inventor: KIPP HERBERT
IPC: G01R15/18
Filed: 2018-10-19
Abstract: The invention relates to a current converter with fluid or oil paper insulation for high voltage, with a head housing (11) through which a primary conductor (3) passes. A measurement device (2) through which the primary conductor (3) passes is arranged in the head housing (11). According to the invention, the primary conductor (3) comprises two different primary conductor types, more specifically an outer tube primary conductor (30) as the first type and one or more inner conductor primary conductors (41, 42, 43) as the second type. The outer tube primary conductor (30) surrounds an interior (35) that is designed to receive the inner conductor primary conductor (41, 42, 43), and the inner conductor primary conductors (41, 42, 43) can be inserted into the interior (35). The special feature lies in the outer tube primary conductor, which is used to transmit power and creates an encasement for the inner conductors. Only the outer tube primary conductor needs to be sealed with respect to the head housing. Inner conductors therefore can be easily inserted or removed subsequently, without the need for sealing measures.
Patent EP-3844316-A1 (EP)
Inventor: MITROPOLSKAYA NATALIA GEORGIEVNA
IPC: C22C14/00
Filed: 2018-08-31
Abstract: This invention generally relates to the field of nonferrous metallurgy, namely to titanium alloy materials with specified mechanical properties for manufacturing the aircraft fasteners. A stock for high strength fastener is manufactured from wrought titanium alloy containing, in weight percentages, 5.5 to 6.5 Al, 3.0 to 4.5 V, 1.0 to 2.0 Mo, 0.3 to 1.5 Fe, 0.3 tol.5 Cr, 0.05 to 0.5 Zr, 0.15 to 0.3 O, 0.05 max. N, 0.08 max. C, 0.25 max. Si, balance titanium and inevitable impurities, having the value of aluminum structural equivalent [Al]eq in the range of 7.5 to 9.5, and the value of molybdenum structural equivalent [Mo]eq in the range of 6.0 to 8.5, where the equivalents are defined by the following equations: [Al]eq =[Al]+[O]x l0+ [Zr]/6; [Mo]eq =[Mo]+[V]/1.5+[Cr]xl.25+[Fe]x2.5. A manufacturing method for a stock for high strength fastener includes melting of titanium alloy ingot, production of forged billed from ingot at beta and/or alpha-beta phase field temperatures, hot rolling at a heating temperature of beta and/or alpha-beta phase field to produce a round stock, subsequent annealing of a rolled stock at a temperature of 550°C to 705°C (1022°F to 1300°F) for at least 0.5 hour followed by drawing to produce a wire with diameter up to 10 mm (0.394 inches) and subsequent annealing at a temperature of 550°C to 705°C (1022°F to 1300°F) for at least 0.5 hour. A technical result is production of a titanium alloy stock for high strength fastener having high ultimate tensile strength and double shear strength while maintaining a high level of plastic properties in the annealed condition.12 claims, 5 illustrations.
Patent EP-3449419-A1 (EP)
Title: Détection d'empreintes digitales à ultrasons et fabrication de capteurs
Inventor: HE YI
IPC: G06K9/00
Filed: 2018-04-09
Abstract: L'invention concerne des systèmes, des dispositifs et des procédés permettant de fournir des capteurs d'empreintes digitales fondés sur des techniques d'imagerie ultrasonore dans des dispositifs électroniques et des techniques de fabrication permettant de produire des capteurs d'empreintes digitales fondés sur les ultrasons. Selon certains aspects, un dispositif de capteurs d'empreintes digitales à ultrasons comprend une couche intermédiaire couplée à une puce de base comprenant un circuit intégré possédant des contacts conducteurs au niveau d'une surface de la puce de base, la couche intermédiaire comprenant une couche d'isolation formée sur la puce de base et un réseau correspondant de structures d'électrodes de canalisation couplées aux contacts conducteurs et passant à travers la couche d'isolation, dans laquelle les électrodes de canalisation se terminent au niveau ou au-dessus d'une surface supérieure de la couche d'isolation afin de fournir des électrodes inférieures ; une pluralité d'éléments transducteurs ultrasonores comprenant un matériau transducteur acoustique couplé aux électrodes inférieures ; et une pluralité d'électrodes supérieures positionnées sur les éléments transducteurs ultrasonores.
Patent EP-3710236-A1 (EP)
Inventor: BETTERMANN THOMAS
IPC: B29C65/40
Filed: 2018-11-14
Abstract: Die Erfindung betrifft ein Verfahren zum Herstellen eines Verstärkungsabschnitts in einem, bevorzugt plattenförmigen, Werkstück, welches Werkstück eine Kernlage, eine erste Decklage und eine zweite Decklage aufweist. Insbesondere handelt es sich bei einem solchen Werkstück um eine Leichtbauplatte. Dabei ist es vorgesehen, dass eine pastöse, aushärtbare Masse mit der Düse in eine Öffnung eingebracht wird, während sich die Düse und/oder das Werkstück während des Ausgebens der Masse zumindest zeitweise bewegt.