baber/WOPTO huggingface dataset:
Patent CN-100454900-C (CN)
Inventor: RU LIANG
IPC: H04L12/70
Filed: 2006-01-24
Granted: 2009-01-21
Abstract: 一种快速响应IP分片报文的方法，包括：IP发送端发送IP分片报文；IP目的端接收所述IP分片报文，判断所述IP分片报文是否需要直接回应，如果是，所述IP目的端在网络层立即发送响应信息到所述IP发送端；否则，所述IP目的端重组所述IP分片报文。通过对IP分片报文的响应处理，缩短了对IP分片报文的响应时间，满足响应处理的实时性要求很高的要求；由于不在IP目的端重组后再响应IP发送端，减少响应时间的重组开销；同时减少了因建立重组队列而遭受攻击的可能性。
Patent CN-100403706-C (CN)
Inventor: JIANFENG MA
IPC: H04L12/26
Filed: 2006-01-11
Granted: 2008-07-16
Abstract: 本发明公开了一种网络安全模拟系统及其仿真方法。该网络安全模拟系统的逻辑功能包括：虚拟网络模块、攻防动态链接库、系统控制模块、呈现模块，这些逻辑功能通过控制层、虚拟网络设备层、公共接口层、中间层、底层函数库具体实现，该虚拟网络设备是在单机上模拟出主机、路由器、防火墙、网卡、集线器、网线，将各虚拟网络设备进行连接就形成虚拟网络。利用该虚拟网络进行安全仿真的过程是：首先设定用户程序、配置系统参数文件，并对系统进行编译；其次将编译好的系统置操作系统环境中进行仿真运行；最后对仿真的数据进行收集并根据收集数据作出网络安全分析。本发明具有使用方便，和可扩充性的优点，用于作为网络安全研究模拟环境和仿真平台。
Patent CN-100386077-C (CN)
Inventor: JUNTAO FENG
IPC: A61K31/365
Filed: 2006-03-14
Granted: 2008-05-07
Abstract: 本发明公开了一种去甲斑蝥素薄膜衣片，其特征是以直径0.5～0.8cm的扁圆形去甲斑蝥素素片为片基，片表面喷雾涂覆有一层厚0.3～1.0mm的包衣材料薄膜衣层。其中，所用的包衣材料为防潮型欧巴代。所述去甲斑蝥素薄膜衣片的制法包括素片制备过程和包薄膜衣过程。本发明的薄膜衣片具有胚片小，使用辅料少，成本低的优点，同时制成的薄膜衣片防潮性能好，稳定性强，药片的溶出速率增加，提高了生物利用度和临床疗效。本发明的去甲斑蝥素薄膜衣片适用于肝癌、食管癌、胃和贲门癌等及白细胞低下症、肝炎、肝硬化、乙型肝炎病毒携带者，亦可作为术前用药或用于联合化疗中，同时解除了对糖尿病患者的使用限制。
Patent CN-100377592-C (CN)
Inventor: QUANWU DONG
IPC: H04N5/93
Filed: 2006-03-20
Granted: 2008-03-26
Abstract: 本发明涉及一种设置电视节目插播点的方法，属于广播电视播出领域。现有技术中，电视台播出的节目单中，很多节目在播出过程中都需要插播其他节目(如广告)，如果插播点的位置选取不当，可能使被插播的节目的情节被强行打断，影响观众的观看感受。本发明所述的方法，在数字自动播出系统中增加了设置节目插播点的流程，即在节目正式播出前预先确定好合适的插播点。采用本发明所述的方法，可以实现对电视节目的插播点的灵活设置，减少了手工操作，提高了播出系统的安全性；同时，插播点的准确性更高更精确，减少了插播失误，给观众以良好的视觉感受。
Patent CN-100441107-C (CN)
Inventor: XUEYUN QU
IPC: A23K20/158
Filed: 2006-05-26
Granted: 2008-12-10
Abstract: 本发明公开了一种肉小鸡生态营养配合饲料，由玉米、豆粕、玉米蛋白粉、赖氨酸、蛋氨酸、豆油、食盐、小苏打、石粉、磷酸氢钙、50%氯化胆碱、复合维生素添加剂、微量元素添加剂、植酸酶、禽用酶制剂、地衣芽孢杆菌、低聚木糖组成。本发明营养搭配合理，能促进肉鸡生长发育，提高免疫能力，达到防病促生长的效果。饲料中不用抗生素，饲料药物残留量为零。
Patent CN-100548817-C (CN)
Title: 一种变频控制抽真空充氮跑粉量的方法
Inventor: YONGZHONG YANG
IPC: H02P27/04
Filed: 2006-09-28
Granted: 2009-10-14
Abstract: 一种变频控制抽真空充氮跑粉量的方法，由真空泵组、能控制真空泵电机工作的变频器、PLC控制器等硬件及相应的控制程序组成，其特征在于：变频器频率P4，P6，P25，P5，P26，P24为正常运行时完成抽真空动作依次运行的频率，当真空度为-30KPa～0时，按面板设置频率工作，-30KPa～-50KPa时按P4频率工作。-50KPa～-60KPa时按P6频率工作，-60KPa～-70KPa时按P25频率工作，-70KPa～-80KPa时按P5频率工作，-80KPa～-90KPa时按P26频率工作，-90KPa～-100KPa时按P24频率工作。采用本发明的变频控制抽真空充氮跑粉量的方法，使规格900克的罐装食品，跑粉量由每罐几十克的损耗降低到了零点几克，而且对整机的工作效率没有产生任何负面的影响。
Patent CN-100486920-C (CN)
Title: 气田甲醇污水处理工艺
Inventor: YONG LI
IPC: C02F1/72
Filed: 2006-10-16
Granted: 2009-05-13
Abstract: 本发明涉及污水处理工艺，特别是气田甲醇污水处理工艺，它至少包括预处理工艺、甲醇回收工艺和污水回注工艺，其特征是：气田污水经除油、调解pH值、氧化除铁、絮凝沉降预处理工艺后，再经过以精馏塔为核心的甲醇回收工艺装置处理，从污水中分离出甲醇，最终实现甲醇回收脱甲醇废水回注地层，最终实现甲醇回收利用，废水零排放的目的。甲醇回收精馏塔采用“填料+筛孔(或斜孔)”及“浮阀+筛孔(或斜孔)”等复合塔型，能较好的解决精馏塔堵塞问题、以及精馏塔对原料水甲醇含量大幅度变化的适应问题。
Patent CN-100495235-C (CN)
Inventor: TAKEO TSUKAMOTO
IPC: G03G15/08
Filed: 2006-10-13
Granted: 2009-06-03
Abstract: 本发明涉及一种可抑制浮垢产生的跳跃式的图像形成装置。该图像形成装置具备表面可移动的调色剂载体，该调色剂载体具备具有在相互绝缘的状态下沿规定方向排列的多个电极的电极图案，通过在以这些多个电极的规定电极为起点的奇数号的电极集合体即奇数号电极组和偶数号电极的集合体即偶数号电极组之间产生电位差，使调色剂载体表面上的调色剂在电极间移动，并且通过调色剂载体的表面移动将其运送到与潜影载体对向的位置，使其附着在所述潜影载体上的潜影上，其中，通过对奇数号电极和偶数号电极分别施加图15所示那样相位互不相同的脉冲电压，使所述调色剂载体表面上的调色剂在两电极间移动。
Patent CN-100564479-C (CN)
Title: 一种红色荧光粉及其制备工艺
Inventor: HAIBO WANG
IPC: C09K11/79
Filed: 2007-04-26
Granted: 2009-12-02
Abstract: 本发明属于发光材料领域，涉及一种红色荧光粉及其制备工艺。该荧光粉的化学式为：(Li 1-a Na a )(Eu 1-b-c-d Sm b Y c Gd d )(SiO 2 ) 1/6 (W 1-m Mo m ) 2 O 8 ，其中0≤a≤0.8，0≤b≤0.08，0≤c≤0.08，0≤d≤0.08，0≤m≤1。本发明采用喷雾热解法制备该荧光粉。按照荧光粉化学式中各阳离子组的化学计量准确称量相应阳离子组中阳离子的可溶性化合物，将其配制成澄清的前驱体溶液，然后经过雾化、反应、收集从而得到该粉。本发明所得荧光粉结晶度高，呈近似球状，粒径分布均匀，颗粒表面光滑，显著提高了粉体的发光效率和色纯度。喷雾热解制备工艺简单，易于操作，生产效率高，适合工业化连续生产。
Patent CN-100564599-C (CN)
Inventor: BAOXUE ZHOU
IPC: C23C22/48
Filed: 2007-10-11
Granted: 2009-12-02
Abstract: 本发明涉及一种高耐蚀性三价铬蓝白色钝化剂及其制备方法，属于金属表面处理技术领域。钝化剂的组成包括含铬2～6g/L的Cr 3+ 化合物，5～8g/L丙二酸，含钴0.5～1g/L的Co 2+ 化合物，1～3g/L氟氢化铵，1～2g/L NaOH，1.5～3g/L NO 3   - ，0.5～1g/L甲酸，含SiO 2 0.4～2g/L的低纳米级尺寸酸性硅溶胶，其余为纯水。钝化剂的制备方法为，将Cr 3+ 化合物、丙二酸、氟氢化铵和Co 2+ 化合物70～100℃加热反应后，于20～30℃添加NO 3   - ，加入甲酸和低纳米级尺寸酸性硅溶胶，加水定容后，得钝化液。本发明的钝化剂，不含有六价铬，生产过程无六价铬污染，钝化时有助于形成均匀、致密钝化层，能够明显提高钝化层的耐蚀性。
Patent CN-100541235-C (CN)
Inventor: YUJI NOGUCHI
IPC: G02B1/118
Filed: 2007-03-01
Granted: 2009-09-16
Abstract: 本发明公开了一种防反射结构，包括：以比可见光线的波长短的间距布置的多个凸起部分，每个所述凸起部分形成为基本上截头锥体和基本上截头棱锥体中的一种，每个所述凸起部分包括：i)形成为底圆和内接于该底圆中的底多边形二者之一的底表面，a)所述底圆和b)外接所述底多边形的所述底圆各自具有满足以下表达式的底直径Db：100nm＜Db＜380nm，ii)形成为上圆和内接于该上圆中的上多边形二者之一的上表面，a)所述上圆和b)外接所述上多边形的所述上圆各自具有满足以下表达式的上直径Du：5nm＜Du＜50nm。
Patent CN-100551112-C (CN)
Title: 一种实现前向信号质量监控的方法、系统和基站
Inventor: YING JIANG
IPC: H04W24/08
Filed: 2007-03-23
Granted: 2009-10-14
Abstract: 本发明提供了一种实现前向信号质量监控的方法，预先在前向反馈信号接收端和后台处理单元之间建立前向信号反馈通道，该方法包括如下步骤：所述前向反馈信号接收端接收前向反馈信号，并将所述前向反馈信号发送给频域信号变换单元；频域信号变换单元将接收到的所述前向反馈信号变换为频域信号；将所述频域信号通过所述前向信号反馈通道输出到后台处理单元，由后台处理单元对所述频域信号的质量进行监控。本发明还提供了一种实现前向信号质量监控的系统和基站，本发明实施例提供的技术方案，将采集到的信号通过前向信号反馈通道输出到后台进行波形质量和频谱波形的分析，从而实现了对前向信号波形质量的自动监控，降低了系统的使用费用。
Patent CN-100551706-C (CN)
Inventor: ATSUHIRO TAKAGI
IPC: B41J2/01
Filed: 2005-03-03
Granted: 2009-10-21
Abstract: 一种墨盒，包括：墨盒体，在该墨盒体中形成墨室；透光部分，该透光部分设置在所述墨盒体上，其中所述透光部分具有形成在其中的内部空间，并且所述内部空间和所述墨室连通；可动构件，该可动构件设置在所述墨室里，并包括第一遮光部分，其中所述第一遮光部分设置在所述透光部分的内部空间内，所述可动构件能够响应于在所述墨室里的墨量的变化而移动；以及第二遮光部分，其中所述第一遮光部分和所述第二遮光部分沿着所述墨盒的安装方向对齐。
Patent CN-100554642-C (CN)
Title: 一种长壁综采回收房式开采煤柱的方法
Inventor: JIXIONG ZHANG
IPC: E21F1/00
Filed: 2007-09-19
Granted: 2009-10-28
Abstract: 一种长壁综采回收房式开采煤柱的方法，在综采工作面的第一排煤柱以及进风巷和回风巷两侧的煤柱间吊挂挡风帘，形成一个可进行长壁综采的通风系统；在综采工作面布置综采设备；在综采工作面前方30m范围内用单体支柱或木垛对进风巷和回风巷的顶板进行超前支护；沿综采工作面推进方向前方5m的煤房内布置一排高支护阻力液压支架，而后进行第一排煤柱的回收；在回收煤柱过程中沿下一排综采工作面的煤柱与煤柱之间吊挂挡风帘，保证回收下一排煤柱时形成通风系统；高支护阻力液压支架随综采工作面液压支架移动而移动，二者始终保持5m左右的距离，从而不断回收煤柱。本方法可回收房式开采留设的永久煤柱85%以上，其方法简便，具有广泛的应用性。
Patent PT-1194690-E (PT)
Inventor: WOBBEN ALOYS
IPC: F03D80/20
Filed: 2000-03-11
Abstract: In the planning and erection of wind power installations the visual impairments to be expected of the wind power installation on the environment are playing an increasingly important part in terms of approval and acceptance. If for example a wind power installation is positioned in the proximity of a residential building, it is possible in adverse positions of the sun, that the wind power installation or the rotor thereof is between the sun and the residential building. If the sunshine is not affected by clouds the rotor as it rotates continuously casts a shadow thereof on the plot of land. The shadow projection caused by the wind power installation on the adjacent area of ground is often perceived by the residents as being a very severe nuisance. Even if the wind power installation satisfies the requirements in terms of legal requirements for planning permission, there is however not always a guarantee that the unwanted shadow effect is prevented.The object of the present invention is to provide a wind power installation by means of which the problems of casting shadows are overcome.1. A method of operating a wind power installation which shuts down at a predetermined position of the sun if the light intensity is above a predetermined value (shut-down intensity).
Patent PT-1186302-E (PT)
Inventor: YOKOYAMA TOMIHISA
IPC: A61K31/41
Filed: 2000-06-09
Abstract: A composition for topical administration having excellent intraocular tension lowering activity is provided. ÄSolutionÜ   An intraocular tension lowering composition for topical administration comprises an angiotensin II antagonist, a boric acid and an ethylenediamine tetraacetic acid.
Patent PT-1223995-E (PT)
Title: Extracorporeal blood purification device
Inventor: FAVRE OLIVIER
IPC: B01D61/14
Filed: 2000-10-26
Abstract: A medium (6) is intended for circulating blood in the outlet. The device further comprises a measuring medium to calculate the pressures of a transfilter and transmembrane, and the flow of ultrafiltrate through an outlet (5). The measuring medium comprises parameters influenced by resistance of filtration medium. The calculating unit (9) comprises pre-dilution control medium to determine a threshold value of the parameter. The control medium is connected by a functioning medium to compare the parameter to the threshold value for maintaining/reducing the resistance of the filtration medium. The pre-dilution control medium to make the circulation of the substitution solution in the measuring duct. The calculating unit: comprises an exchange control medium that are connected to the ultrafiltration circulation medium to adapt the value of ultrafiltrate flow; extending the duration of the treatment until the degree of purification is obtained; undergoes a cleaning of filtration medium while controlling the circulation of substitution solution in the measuring duct. The exchange control medium is programmed to calculate flow of pre-dilution control medium in the calculating unit. The extraction duct (1) comprises a flow sensor that is connected to the calculating unit having a control unit for increasing the speed of blood extraction pump until increase the flow of extracted blood that does not increase linearly with the pump.
Patent PT-1242671-E (PT)
Title: Enzymes useful for changing the properties of polyester
Inventor: YOON MEE-YOUNG
IPC: D06M101/32
Filed: 2000-10-10
Abstract: A polyesterase enzyme which produces a positive result in an UV and/or MB assay is used to treat polyester to modify polyester properties such as pilling, pilling prevention, weight, feel, appearance and luster.
Patent PT-1243010-E (PT)
Inventor: CHARLES CYRIL
IPC: H01R13/68
Filed: 2000-12-26
Abstract: A safety device for monitoring heat for connection in electrical installations, comprises a first connecting element (14) in thermal relationship with an electrical connection to be monitored. A second element (35) is also designed to be connected to the ground of the general electric installations. Electrical connecting structure (21) connects the two elements and can adopt two states, one an insulating state in normal operating conditions and the other an interrupting state wherein there is contact and hence earthing of the first element with the second when a critical temperature is reached.
Patent PT-1186231-E (PT)
Inventor: ZEMACH SHALOM
IPC: A01K61/00
Filed: 2001-08-10
Abstract: The invention provides a deep-water fish farming system comprising a fish cage (200) of controllable buoyancy having one or more chambers (202), which can be submerged and refloated at a controllable rate to any depth. A winch mechanism (214) mounted preferably on a platform that covers a section of the cage releases and gathers a cable connected to a sinker (306). When the combined weight of the system overcomes the buoyancy, the fish cage is submerged to a depth determined by the effective length of the cable between the winch mechanism and the sinker, with the sinker touching the sea bottom. The submerged cage is refloated to the surface by remotely activating the winch mechanism, thus releasing the cable, while keeping the sinker on the sea bottom. When the cage is refloated to the surface, the buoyancy is increased to allow pulling of the sinker from the bottom. The invention further provides a method for submerging and raising a fish cage at a controlled rate to any desired depth in deep water. <IMAGE>
Patent PT-1253201-E (PT)
Title: Chicken anemia virus mutants and vaccines based on the viral protein vp3 or sequences of that virus coding therefor
Inventor: KOCH GUUS
IPC: C12N5/10
Filed: 1994-07-19
Abstract: Novel proteins of the Chicken Anemia Virus are described and compositions for preventing or treating infections with that virus (CAV), in particular vaccines less pathogenic than the CAV itself, but yet leading to neutralizing antibodies in the immunized animal. Besides, there are described compositions containing antibodies against parts of the CAV for the control of infections with CAV and anti-idiotype antibodies which possess an immunogenicity corresponding to the antigen. The invention also provides antibodies for the detection of CAV infections and test kits for the detection of CAV. Recombinant DNA molecules derived from CAV coding for an immunogenic part of a CAV protein and host cells transfected with such DNA molecules and vaccines based on these host cells are made possible by this invention. Also, living virus vaccines in which a piece of DNA coding for an immunogenic part of a CAV protein is brought into a virus infectious to the desired host are a subject of the invention. Besides, the invention relates to uses of proteins of CAV in the induction of apoptosis, in particular, the proteins can be used in induction of apoptosis in tumor cells. The invention further provides the induction of cell death by means of gene therapy.
Patent PT-1146125-E (PT)
Inventor: BALLOUL JEAN-MARC
IPC: C07K14/07
Filed: 2001-04-12
Abstract: The present invention concerns a poxviral particle having a targeted infection specificity conferred by an heterologous ligand moiety present at the surface of said poxviral particle and capable of specifically recognizing and binding to an anti-ligand molecule localized at the surface of target cells. The present invention further relates to a vector comprising a nucleotide sequence encoding a chimeric polypeptide including such an heterologous ligand moiety and all or part of a natural poxviral surface polypeptide. The present invention additionally concerns compositions comprising said poxviral particle or said vector as well as their use for therapeutic and prophylactic purposes. The invention is of very special interest in gene therapy applications, in particular in preventing or treating cancer in mammals.
Patent PT-1182360-E (PT)
Inventor: MICHEL SCHMIDT
IPC: F15B15/28
Filed: 2001-06-19
Abstract: The sensor (1) has an upper surface which when mounted in a slot (4) of a fixing rail (3) is flush with it so as to protect against knocks. A plate (8) positioned in the slot holds the sensor supply cable in the base of the slot. The rail (3) is fixed on the body of the jack and forms an integral part of it.  Sensor fixing comprising a rail (3) mounted on the external surface of the body of the jack and along its axis. The rail has a slot (4) with a section designed to receive the sensor. The sensor includes a pivot (5) fixed by a screw (6) or similar. The pivot occupies two positions produced by rotation of the screw. In a first position the pivot is flush with the lateral walls of the sensor so as to allow the mounting of the sensor from the top of the slot. In a second position, the pivot projects from the lateral walls of the sensor so as to lodge itself in the bottom of the slot and lock the sensor without subjecting it to any compression force.
Patent PT-1285140-E (PT)
Title: Stormwater management system
Inventor: KRUGER KURT J
IPC: E03F1/00
Filed: 2001-05-04
Abstract: Disclosed is a fluid, namely stormwater, management system employing a chamber having an overall substantially constant curve cross-sectional geometry, with an a-semicircular constant curve cross-sectional geometry preferred. This chamber, which preferably follows both AASHTO standard specifications for Highway Bridges, Section 18, and Corrugated Polyethylene Pipe Association (CCPA) specifications, can further comprise corregations, support members and/or connecting elements to further add structural integrity.
Patent PT-1335728-E (PT)
Inventor: CHRISTEL SCHMELZER
IPC: A61P11/00
Filed: 2001-11-09
Abstract: Drug compositions containing one or more tiotropium salts and one or more salmeterol salts, are new. Drug compositions containing one or more tiotropium salts and one or more salmeterol salts, are new. The salts can be present in the form of enantiomers, enantiomer mixtures or racemates as well as in the form of solvates or hydrates. The compositions may also contain a pharmaceutical adjuvant. ACTIVITY : Antiasthmatic. MECHANISM OF ACTION : Anticholinergic; beta -mimetic.
Patent PT-1445085-E (PT)
Title: Method of manufacturing a sandwich panel
Inventor: KLENKE DETLEV
IPC: B29C44/32
Filed: 2003-03-04
Abstract: A process for producing a multi-layered laminar board (1) which consists of a hard foam layer (2) sandwiched between two cover layers (3a,3b), comprises continuously unwinding two cover layers from a roll, and feeding them to a twin band unit (31). A foamable mixture (21) is supplied to the space between the bands, and foamed to form a hard foam layer. An adhesive (4) is applied to one of the covering layers using a coating unit (24). The adhesive is rolled or painted on, and consists of a heat activated thermoplastic. The hard foam is polyurethane and the cover layers are paper or card.
Patent PT-1741785-E (PT)
Title: Porcine circoviruses, nucleic acids, polypeptides and vaccines
Inventor: ALLAN GORDON
IPC: G01N33/53
Filed: 1998-10-01
Abstract: A purified preparation of type II porcine circovirus (PCV). Independent claims are also included for the following: (a) preparation of PCV (i) isolated from a physiological or tissue sample, particularly from a lesion, from a pig with symptoms of PMWS (porcine multisystemic wasting syndrome); or (ii) produced by, and isolated from, in vitro cell cultures infected with the virus of (i); (b) extract or culture supernatant, or antigen preparation, optionally purified, collected from in vitro cultures of cells infected with PCV; (c) vaccine containing the products of (b); (d) DNA fragments (A) of 1767 bp (1), 1767 bp (2), 1767 bp (3), 1768 bp (4) or 1768 bp (6), or containing an open reading frame (ORF) of PCV; (e) polypeptides (I) encoded by (A) or these ORF; (f) in vitro expression vector containing (A), or these ORFs; (g) polypeptides (Ia), optionally purified, expressed from the vector of (f); (h) subunit vaccine containing at least one (I) or (Ia), diluent or vehicle and optionally an adjuvant; (i) in vivo expression vector, integrated into a genome, containing (A) or the ORFs; (j) live or plasmid vaccine containing the vector of (j), and a diluent or vehicle; (k) probe or primer containing all or part of (A) or the ORFs; (l) mono- or poly-clonal antibodies raised against PCV, (I), (Ia) or their fragments; and (m) detection of PCV by identifying in a body fluid or tissue sample an antigen or antibody specific for the antigen. ACTIVITY : Antiviral. MECHANISM OF ACTION : Induction of an immune response against porcine circovirus; vaccine.
Patent PT-1759704-E (PT)
Title: Metal compounds, mixed or sulphated, as phosphate binders
Inventor: WEBB MAURICE
IPC: C01B32/60
Filed: 1998-09-18
Abstract: A mixed metal compound for pharmaceutical use is free from aluminium and has a phosphate binding capacity of at least 30 %, by weight of the total weight of phosphate present, over a pH range of from 2-8. The compound is especially useful for treatment of hyperphosphataemia. The metals are preferably iron (III) and at least one of calcium, magnesium, lanthanum and cerium. A metal sulphate for pharmaceutical use is selected from at least one of calcium, lanthanum and cerium sulphate compounds and has a phosphate binding capacity of at least 30 % by weight of the total phosphate present, over a pH range from 2-8.
Patent PT-1870417-E (PT)
Title: Peptide acceptor ligation methods
Inventor: LOHSE PETER
IPC: C07K14/00
Filed: 2000-07-19
Abstract: Described herein are methods and reagents for the ligation of a peptide acceptor to an RNA, as well as the RNA-peptide acceptor products.
Patent PT-2066344-E (PT)
Title: Inactivated poliovirus combination vaccine
Inventor: HEMPTINNE HERVE DE
IPC: A61K39/13
Filed: 2007-09-07
Abstract: The present invention relates to the field of vaccines for protecting against polio, and in particular to combination vaccines for protecting against polio, diphtheria, tetanus, and pertussis diseases. Specifically, vaccines comprising reduced dose inactivated poliovirus (IPV) is provided, which can maintain an adequate or improved level of protection against polio.
Patent PT-2508316-E (PT)
Title: Method for manufacturing gypsum products
IPC: C04B38/10
Filed: 2011-04-08
Abstract: A method and system for producing a gypsum product comprising a mixer for mixing gypsum and water and two foam feeds into the system wherein the foam feeds each comprise foam of different bubble size distributions.
Patent PT-689434-E (PT)
Inventor: JONES ROGER SPENCER
IPC: A61K31/195
Filed: 1994-03-08
Abstract: An improved process for the production of a pharmaceutical composition comprising p-hydroxyacetanilide and L-cysteine or a compound which is converted thereto in vivo comprises mixing p-hydroxyacetanilide and L-cysteine or its precursor in the solid state and then shaping the solid mixture.
Patent PT-680964-E (PT)
Inventor: FAIRCLOTH GLYNN THOMAS
IPC: A61P35/00
Filed: 1994-11-18
Abstract: The new pirrolo [3,2-e]indol derivatives have the formulae (I), (Ia) and (II) wherein R is substituted or unsubstituted aryl or heteroaryl, R' is substituted or unsubstituted alcanoyl, alkenoyl, alkinoyl, arenocarbonyl or heterareocarbonyl and X is chloro, bromo, iodo or alkylsulfonyl or arylsulfonyl. The process comprises: (a) deacylating (VII) in order to obtain (VIII); (b) subjecting (VIII) to a cyclopropyl ring opening raction in order to give (IX); (c) reacting (IX) with acid R-COOH in order to yield (I); (d) optionally, reacting (I) with a base in the presence of a condensing agent in order to obtain (II); (e) optionally, reacting (I) with a carboxylic acid in the presence of a condensing agent or with an acid chloride in the presence of a base to give (Ia). The compounds (I), (Ia) and (II) find application as agents having antitimoral activity for the treatment of cancer. <CHEM>
Patent PT-777669-E (PT)
Inventor: WILSON JEFFREY DOUGLAS
IPC: A61K31/52
Filed: 1995-08-25
Abstract: The present invention relates to the succinate salt of (1S,4R)-<u>cis</u>-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol or a solvate thereof, to pharmaceutical formulations containing such a compound or pharmaceutical formulations, and to its use in medical therapy or in methods of treatment or prophylaxis of a viral infection, specifically human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infection.
Patent PT-804601-E (PT)
Inventor: SEDLACEK HANS-HARALD
IPC: A61P35/00
Filed: 1995-08-25
Abstract: PCT No. PCT/EP95/03370 Sec. 371 Date Apr. 18, 1997 Sec. 102(e) Date Apr. 18, 1997 PCT Filed Aug. 25, 1995 PCT Pub. No. WO96/06940 PCT Pub. Date Mar. 7, 1996A DNA sequence for the gene therapy of tumors is described. In its essential elements, the DNA sequence is composed of an activator sequence, a promoter module and a gene for the active substance. The activator sequence is activated, in a cell-specific manner, in proliferating endothelial cells or in cells which are adjacent to these endothelial cells. This activation is regulated by the promoter module in a cell cycle-specific manner. The active substance is an inhibitor of angiogenesis or a cytostatic or cytotoxic molecule. The DNA sequence is inserted into a viral or non-viral vector which is supplemented with a ligand which possesses affinity for the activated endothelial cell.
Patent PT-1012295-E (PT)
Inventor: DAVIS NANCY L
IPC: A61K39/00
Filed: 1996-05-21
Abstract: The present invention provides a helper cell for expressing an infectious, replication defective, alphavirus particle in an alphavirus-permissive cell. The helper cell includes (a) a first helper RNA encoding (i) at least one alphavirus structural protein, and (ii) not encoding at least one alphavirus structural protein; and (b) a second helper RNA separate from the first helper RNA, the second helper RNA (i) not encoding the alphavirus structural protein encoded by the first helper RNA, and (ii) encoding the at least alphavirus one structural protein not encoded by the first helper RNA, such that all of the alphavirus structural proteins assemble together into alphavirus particles in the cell. Preferably, the helper cell also includes a replicon RNA encoding an alphavirus packaging sequence and an inserted heterogeneous RNA.