baber/WOPTO huggingface dataset:
Patent CA-2739460-A1 (CA)
Title: Cd86 antagonist multi-target binding proteins
Inventor: THOMPSON PETER ARMSTRONG
IPC: C07K16/28
Filed: 2009-10-02
Abstract: This disclosure provides a multi-specific fusion protein composed of a CD86 antagonist binding domain and another binding domain that is an IL-10 agonist, an HLA-G agonist, an HGF agonist, an IL-35 agonist, a PD-1 agonist, a BTLA agonist, a LIGHT antagonist, a GITRL antagonist or a CD40 antagonist. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.
Patent CA-2742191-A1 (CA)
Inventor: ARIGA TOHRU
IPC: F24F1/0375
Filed: 2011-06-07
Abstract: In an air conditioning device (1) that includes: a PTC heater (55) in which, in a stable region (S1), when the temperature of the PTC heater (55) is increased, a resistance is decreased or is substantially constant whereas, in a rise region (S2), the resistance is rapidly increased when the temperature exceeds a rise temperature (T1); and an air blower (25) that generates an air current which exchanges heat with the PTC heater (55), and that performs a heating operation by discharging air heated by the PTC heater (55) into the room, when the temperature within the room is within a low temperature range including a region whose temperature is lower than a set temperature, the duty ratio is set at 100%, and the PTC heater (55) is driven in the rise region (S2), when the temperature within the room is within a high temperature range whose temperatures are higher than the set temperature, the PTC heater (55) is stopped, and when the temperature within the room is within an intermediate temperature range between the low temperature range and the high temperature range, the duty ratio is set at a predetermined duty ratio, and the PTC heater (55) is driven in the stable region (S1).
Patent CA-2742515-A1 (CA)
Title: 1,4-diazepane modulators of cxcr7
Inventor: CHEN XI
IPC: A61K31/551
Filed: 2009-11-04
Abstract: Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present invention provides in further aspects, compositions containing one or more of the above-noted compounds in admixture with a pharmaceutically acceptable excipient.
Patent CA-2746290-A1 (CA)
Title: An optimized aerodynamic profile for a turbine blade, in particular for a rotary wheel of the fourth stage of a turbine
Inventor: GIRARD PATRICK
IPC: F01D5/02
Filed: 2011-07-15
Abstract: When cold and in the non-coated state, the aerodynamic profile is substantially identical to a nominal profile determined by the Cartesian coordinates X,Y,Z' given in Table 1, in which the coordinate Z' is the quotient D/H where D is the distance of the point under consideration from a first reference plane P0 situated at the base of the nominal profile, and H is the height of said profile measured from the first reference plane to a second reference plane P1. The measurements D and H are taken radially relative to the axis of the turbine, while the X coordinate is measured in the axial direction of the turbine.
Patent CA-2746560-A1 (CA)
Title: Humidifying apparatus
Inventor: FITTON NICHOLAS GERALD
IPC: F24F1/01
Filed: 2010-02-18
Abstract: Humidifying apparatus comprises a fan assembly (10) and, located behind the fan assembly, a humidifier (100) for emitting moist air into the atmosphere. The fan assembly (10) comprises means (52, 56) for creating an air flow and a nozzle (14) comprising an interior passage (86) for receiving the air flow and a mouth (26) for emitting the air flow. The nozzle (14) extends about and defines an opening (24) through which both air from outside the nozzle (14) and the moist air emitted from the humidifier (100) are drawn by the air flow emitted from the mouth (26).
Patent CA-2747807-A1 (CA)
Inventor: NEUSTADT BERNARD R
IPC: A61P3/10
Filed: 2009-12-21
Abstract: The present invention relates to Pyriraidine Derivatives of formula (I), compositions comprising a Pyrimidine Derivative, and methods of using the Pyrimidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G protein -coupled receptor (GPCR) in a patient.
Patent CA-2747963-A1 (CA)
Title: Visco-elastic body support and method of manufacturing the same
Inventor: MIKKELSEN TOM D
IPC: A47C7/18
Filed: 2009-12-21
Abstract: A pillow assembly including a foam core having a top surface, side surface, and bottom surface, and an outer layer covering the top surface and side surface and leaving the bottom surface substantially exposed.  The foam core has a higher hardness and a higher density than the outer layer.    The foam core and the outer layer comprise reticulated or non-reticulated visco-elastic foam. The outer layer covers a majority of the foam core and has a substantially constant thickness across the top surface. The foam core includes a front side and a back side, both of which are covered by the outer layer and left and right sides of the foam core, which are exposed.
Patent CA-2752708-A1 (CA)
Title: Filter cloth for a belt filter
Inventor: GIER-ZUCKETTO JOACHIM
IPC: B01D39/08
Filed: 2010-05-12
Abstract: The present invention relates to a filter cloth for a belt filter, wherein the filter cloth has an air permeability of 100 1/ (min*dm2) to 350 1/ (min*dm2) and fibers of the filter cloth have a fiber thickness of 25 µm to 35 pm and contain from 50% by weight to 100% by weight of perfluoroalkoxylalkane (PFA). The filter cloth has 25 to 35 warp threads (3) and 15 to 25 weft threads (2) per 1 cm.
Patent CA-2754439-A1 (CA)
Title: Messaging interface for advertisement submission
Inventor: VIJAYAKRISHNAN SIDDHARTH
IPC: G06Q30/00
Filed: 2010-03-02
Abstract: Methods, systems, and apparatus, including computer program products, in which submission of targeted advertisements can be facilitated using text messaging.  Text message received from advertisers can include advertisement information and target audience information. Such information can be used to generate an advertisement for the advertiser. The generated advertisement can be provided for targeted distribution to users.
Patent CA-2755872-A1 (CA)
Title: Manchon de protection pour conduite flexible
Inventor: ESPINASSE PHILIPPE
IPC: F16L1/12
Filed: 2010-03-22
Abstract: L'invention concerne un manchon de protection apte à être installé autour d'une portion longitudinale de conduite (72) destinée au transport des hydrocarbures. Ledit manchon comprend un ensemble d'anneaux présentant chacun deux flancs opposés (16, 18), et étant successivement maintenus ensemble, les flancs (16, 18) en regard par une pluralité d'éléments de liaison (32) élastiquement déformables. La flexion de ladite portion longitudinale est apte à provoquer la contraction des éléments de liaison (32) situés vers l'intérieur de la courbure et l'allongement des éléments de liaison (32) opposés pour résister à la flexion. Selon l'invention, chaque élément de liaison (32) présente deux parties de fixation rigides opposées (34, 36) et un corps élastique déformable (38) interposé entre lesdites deux parties de fixation. Lesdites parties de fixation (34, 36) sont respectivement fixées dans les flancs (16, 18) en regard desdits anneaux (10).
Patent CA-2757254-A1 (CA)
Title: Deformable transportable bioreactor chamber
Inventor: PORTER BLAISE
IPC: C12M1/26
Filed: 2010-03-19
Abstract: An apparatus and method is described for seeding and culturing cells on a sample. The apparatus includes a chamber in which the volume of the chamber may be adjusted without compromising the seal or sterility of the chamber. The apparatus enables the seeding of cells in a reduced volume and culturing of cells in an increased volume. Further, the apparatus enables application of forces, strains and torques to a sample during seeding, culturing or transportation of the sample.
Patent CA-2757620-A1 (CA)
Inventor: DAVIS HEATHER LYNN
IPC: A61K39/39
Filed: 2010-03-17
Abstract: The present invention relates to new pneumococcal vaccines. The invention also relates to vaccination of subjects, in particular immunocompromised subjects, against pneumoccocal infections using said novel pneumococcal vaccines.
Patent CA-2757942-A1 (CA)
Title: Integrated brushless starter/generator system
Inventor: SHAFER DOUGLAS GEORGE
IPC: H02K1/32
Filed: 2010-03-12
Abstract: A brushless startor/generator includes a rotor rotatably mounted within a stator mounted within a housing and an oil cooling system using cooling oil from an en-gine accessory gearbox for cooling the rotor and the stator. The rotor is fixedly mounted on a rotor shaft having a rotor heat exchange dis-posed therein. A stator heat exchanger for cooling the stator includes an oil jacket around the housing. The stator heat exchanger includes a grooved tube around the housing and axially extending axial passages connect-ed to annular inlet and outlet manifolds in the grooved tube. The rotor shaft is operably con-nected to a power take-off shaft within the gearbox and rotatably supported by a shaft bearing in a gearbox casing of the accessory gearbox. The oil cooling system is a dry cavity oil cooling system which prevents cooling oil from entering an air gap between the rotor and the stator.
Patent CA-2760145-A1 (CA)
Title: Sku level control and alerts
Inventor: CARLSON MARK
IPC: G06Q20/00
Filed: 2010-04-27
Abstract: Embodiments of the present invention are directed to a system and method for determining the products involved in a transaction conducted with a subsidiary user of a payment account, and transmitting messages containing product specific in-formation. Systems may be implemented to transmit product identifiers during payment processing. The product specific informa-tion may be included in alert messages sent to an account holder.
Patent CA-2760208-A1 (CA)
Title: Abrasive article with improved grain retention and performance
Inventor: ZHANG HAN
IPC: B24D18/00
Filed: 2010-04-28
Abstract: An abrasive article with improved grain retention and performance and method of making are disclosed. The abrasive article with improved grain retention results in an article with improved performance and longer article life.
Patent CA-2762651-A1 (CA)
Inventor: MEEKER DOUGLAS C
IPC: G06Q30/02
Filed: 2011-12-21
Abstract: According to embodiments of the invention, a computer system extends an invitation to a plurality of content generators to request authentic content relating to one or more selected topics. The computer system receives content generated in response to the invitation and publishes that content online. The computer system calculates an efficacy of the request by obtaining data regarding to the online content and user interactions with the content. The computer system is configured to obtain data corresponding to user interactions with the content on the website hosting the content as well as user interactions with the content on third party websites such as Facebook® or Twitter®. Using that data, the computer system calculates an efficacy of the request.  The computer system may also generate one or more reports to convey the calculated efficacy of the request.
Patent CA-2765096-A1 (CA)
Title: Managed real-time transaction fraud analysis and decisioning
Inventor: FISHER RICHARD
IPC: G06Q20/00
Filed: 2010-05-24
Abstract: A system, apparatus, and method for providing real-time or pseudo real-time processing of transactions for a set of clients using a common or partially common rule base. Each client is assigned to a tier or category with the tier or category defined by specified performance criteria. In some embodiments, the specified performance criteria includes a false positive ratio (FPR). A rule for processing transactions is defined as a combination of an interval of a scoring range of a first risk assessment scoring system and an interval of a scoring range of a second risk assessment scoring system. A proposed rule is tested by determining if its performance falls within a defined range of the performance criteria when applied to data for previous transactions.
Patent CA-2768384-A1 (CA)
Title: Method for producing a stable oxidizing biocide
Inventor: GUPTA AMIT
IPC: A01N59/00
Filed: 2010-08-19
Abstract: The invention relates to a production method for producing stable chloramine. The method allows for the production of stable chloramine with the use of concentrated Chlorine source and concentrated amine source and agitation during production. The method produces a chloramine that has a pH of at least 5 with a most preferred pH of at least 7 or greater.
Patent CA-2768794-A1 (CA)
Inventor: BURNS FRANK R
IPC: C12Q1/68
Filed: 2010-07-20
Abstract: Pathogenicity in Escherichia coli strains has been linked to serotypes defined by 0 and H antigens. In particular, E. coli 0157:H7 is associated with several food and water borne disease outbreaks. There remains a need to detect E. coil 0157:H7 even in the presence of other, similar E. coli serotypes. The present specification provides methods for the detection and characterization of E. coli 0157:H7 based on the presence of nucleic acid molecules in samples. Also provided are nucleic acid sequences for primers and probes used in such methods.
Patent CA-2770921-A1 (CA)
Title: Apparatus and method for gas turbine engine vane retention
Inventor: ELEFTHERIOU ANDREAS
IPC: F01D9/02
Filed: 2012-03-08
Abstract: A vane assembly of a gas turbine engine has a plurality of vanes extending radially and inwardly from an annular casing. An outer end of each vane radially and outwardly projects from the casing and is received in one of apertures defined in an elastomeric ring which is placed around the casing. A strap of a non-metallic material is placed in a pre-tensioned condition around the elastomeric ring to compress the elastomeric ring and to radially retain the outer end of each vane.
Patent CA-2773433-A1 (CA)
Title: Method for the preparation of an influenza virus
Inventor: MACHUY NIKOLAUS
IPC: C12N7/02
Filed: 2010-09-10
Abstract: The present invention relates to a method for the preparation of a pharmaceutical composition for the prevention or/and treatment of an influenza virus infection.
Patent CA-2773950-A1 (CA)
Title: Electrode system and sensor for an electrically enhanced underground process
Inventor: MORYS MARIAN
IPC: E21B43/25
Filed: 2012-04-05
Abstract: An electrically stimulated electrode system 100 may comprise injection and return electrodes 110, 112 and a power supply 120 for causing electrical current to flow through a subterranean formation 104. An electronic system 200 for the injection electrode may include: a power harvester 210 for extracting electrical power from current flowing in the injection electrode, or a current control 300 for the current flowing through the injection electrode, or a sensor 400 of the injection electrode and/or the formation, or a telemetry 400 for receiving a parameter relating to the injection electrode and/or the formation, or any combination thereof. A sensor 210e, 400 may comprise: a pair of spaced apart electrodes 212e, a power conversion device 220 connected to the pair of spaced apart electrodes for providing electrical power, and a processor 420 for providing a representation of a current. The electronic system 100 may include: a power harvester 200, a commandable and/or programmable current control 300; and a control system 130, 400 for commanding and/or programming the current control, whereby the current flowing in the injection electrodes 110 may be independently controlled and/or sequenced in time.
Patent CA-2774441-A1 (CA)
Title: Antibodies immunoreactive with mutant hydroxypenylpyruvate dioxygenase
Inventor: SEKAR VAITHILINGAM
IPC: C07K16/40
Filed: 2010-10-26
Abstract: Antibodies immunoreactive to mutant Pseudomonas HPPD are provided, and in an embodiment the mutant HPPD is one in which the wild-type HPPD is substituted at residue 336 with tryptophan for glycine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.
Patent CA-2774861-A1 (CA)
Title: Utilisation d'activateurs de canaux potassiques k2p en tant qu'antalgiques
Inventor: ESCHALIER ALAIN
IPC: G01N33/68
Filed: 2010-09-21
Abstract: La présente invention concerne le traitement et la prévention de la douleur. Plus particulièrement, la présente invention démontre l'implication des canaux potassiques K2P dans l'effet antalgique de la morphine. La présente invention fournit donc une méthode de criblage pour l'identification d'antalgiques.
Patent CA-2776592-A1 (CA)
Inventor: BHALLA SANDEEP
IPC: B26B3/02
Filed: 2012-05-04
Abstract: This is a child friendly cake knife with an animal shaped handle to be used for cutting birthday and any other celebration cakes. I t has a small grip to allow the child to grip the knife manually by placing his fingers and palm around the handle shaped as an elephants body. Then by placing the blade lengthwise on the cake surface and pushing down horizontally using his own strength the cake will be cut. The plastic material used is safe for food use. It is also lightweight to enable a young child to lift it. The whole object is also made of plastic to ensure it cannot cause a cut or injury to the child. The blade itself has semi circular blunt edges sufficient to cut a cake but safe enough to prevent injury to the child. The knife uses an animal shape to provide an attractive concept to the child.  The feet of the animal are sufficiently wide to enable to knife to stand up on those feet. The knife has a hole in the eye of the animal to allow a bow or ribbon to be tied to the item to reiterate the celebration where the knife is being used and to enhance the product appeal to the child.
Patent CA-2777636-A1 (CA)
Inventor: MARTEL DAVID
IPC: F16B1/00
Filed: 2007-04-16
Abstract: Une fixation dissimulée qui permet de fixer des éléments de platelage rainurés latéralement adjacents à un support sous-jacent comprend un corps avec une ouverture pour fixation, une première et une seconde ailette de raccordement, et une bride. Les ailettes dépassent du bord supérieur du corps en sens contraires. Chaque ailette comprend une première partie perpendiculaire au corps et une seconde partie orientée à un angle par rapport à celui-ci. La bride est perpendiculaire au corps et est fixée au rebord inférieur. En utilisation, l'ailette opposée à la bride est placée dans la rainure du premier élément de platelage. Un raccord est fixé dans le support à travers l'ouverture, ce qui fait que la fixation et l'ailette fléchissent dans la partie d'engagement avec l'élément de platelage. Un second élément de platelage est placé latéralement contre le premier en déplaçant sa rainure latérale sur l'autre ailette, ce qui produit la flexion de l'ailette pour l'engagement.
Patent CA-2778747-A1 (CA)
Inventor: HAGEMEYER BRUCE
IPC: E05B63/00
Filed: 2012-06-01
Abstract: A lock includes a housing and a slide mechanism adapted to translate in the housing along a locking axis. The lock includes one or more locking elements connected to the slide mechanism. The locking elements translate along the locking axis with the slide mechanism.
Patent CA-2780615-A1 (CA)
Inventor: SHIZUKU FUMISHIGE
IPC: H01M8/02
Filed: 2010-05-26
Abstract: The disclosed fuel cell stack is provided with: a first module which includes an electrolyte film, an anode and a cathode; a second module which includes a separator and is disposed adjacently to one surface of the first module with an interposed first seal member; and a third module which includes a separator and is disposed adjacently to the other surface of the first module with an interposed second seal member. In such a fuel cell stack, the peel strength of the first seal member with the first module is greater than that with the second module, and the peel strength of the second seal member with the first module is greater than that with the third module.
Patent CA-2780766-A1 (CA)
Title: Tracheal tube and tube extension
Inventor: BURNS JOHN P
IPC: A61M16/04
Filed: 2010-12-10
Abstract: The present disclosure describes systems that may extend the proximal length of a tracheal tube. A tracheal tube extension system may be provided that includes secure attachment features ( 38, 42 ) used to securely couple a tracheal tube ( 12 ) to a tracheal tube extension ( 26 ). The tracheal tube extension may be attached to the proximal end of the tracheal tube and includes an upper end connector ( 32 ). The upper end connector may be used to couple the tracheal tube extension to a variety of medical devices such as a ventilator ( 28 ), a manual respirator, a nebulizer, a vaporizer, suctioning equipment, and so forth. The use of the tracheal tube extension enables an increase in working space in the area in front of the tracheal tube, thus allowing for the convenient and rapid access to the various connectors that may be coupled to the patient.
Patent CA-2782266-A1 (CA)
Title: Anticancer compounds and screening method
Inventor: FRINCKE JAMES M
IPC: A61K31/56
Filed: 2010-11-30
Abstract: The invention provides a method to identify or characterize compounds for treating cancer wherein the compounds have a capacity to decrease systemic levels of one or more cholesterol metabolites in treated mammal(s). Such compounds include 17-(3-pyhdyl)androst-5,16-diene-3ß,7ß-diol, 17-(2- morpholinyl)-7ß-ethylandrost-5,16-diene-3ß-ol, 17-(2-morpholinyl)-7ß- ethylandrost-5,16-diene-3ß-ol-16-acetate, 17-(4-oxazolyl)-7ß-ethylandrost- 5,16-diene-3ß-ol-16-methyl ether and 17-(4-oxazolyl)-7ß-ethylandrost-5,16- diene-3ß-ol. Compositions and formulations comprising the compounds and one or more excipients are also provided.
Patent CA-2782834-A1 (CA)
Title: Toy systems
Inventor: TRICKETT ALASTAIR J C
IPC: A63H11/00
Filed: 2010-11-03
Abstract: A toy system comprises a surface (1) provided with position encoding information; and a toy (2, 20) arranged to be movable across the surface (1), said toy (2, 20) comprising at least one sensor (4) for reading said position encoding information, and processing means (3) arranged to process the position encoding information read by the sensor (4) and to determine the position of the toy (2, 20) on said surface (1) on the basis of said position encoding information.
Patent CA-2783475-A1 (CA)
Title: Heterocyclic compounds as janus kinase inhibitors
Inventor: BABU YARLAGADDA S
IPC: A61K31/519
Filed: 2010-12-22
Abstract: The invention provides compounds of formula (I): (Formula (I)), or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I) and therapeutic methods for suppressing an immune response or treating cancer or a hematologic malignancy using compounds of formula (I).