baber/WOPTO huggingface dataset:
Patent WO-2020257808-A1 (WO)
Title: Procédés de guidage d'administration directe de médicaments et/ou d'énergie à des lésions par modélisation informatique
Inventor: KINSEY C MATTHEW
IPC: A61N5/00
Filed: 2020-06-22
Abstract: La présente invention concerne un procédé de traitement d'une tumeur consistant à obtenir une imagerie 3D de la tumeur; à traiter l'imagerie 3D de la tumeur afin d'obtenir une morphologie de la tumeur; à déterminer un certain nombre de sites de traitement, des emplacements de ces sites, et la posologie à l'aide d'un modèle de dynamique de traitement intratumoral entre l'espace vasculaire, intracellulaire et extracellulaire afin que la tumeur reçoive une dose thérapeutique à chaque emplacement de la tumeur; et à traiter la tumeur au niveau de chacun des sites de traitement déterminés et à l'aide la posologie déterminée. Selon certains modes de réalisation, le procédé consiste en outre à générer le modèle afin d'inclure une pluralité de volumes interconnectés, chaque volume ayant un ou plusieurs volumes adjacents avec une limite partagée. Une ou plusieurs simulations de traitement dans le temps peuvent être effectuées à l'aide du modèle, chaque simulation ayant un ensemble d'un ou plusieurs paramètres initiaux.
Patent WO-2020263771-A1 (WO)
Inventor: SHAFER GLEN
IPC: F04B53/16
Filed: 2020-06-23
Abstract: A chemical dispenser (14) includes a housing (40), a controller (34) disposed in the housing (40) for operating the chemical dispenser (14), at least one module bay (64) in the housing (40) and at least one module (66) selectively coupled to the at least one module bay (64) and operatively coupled to the controller (34) for operation with the chemical dispenser (14). The at least one module (66) may be selected from a plurality of modules each capable of being coupled to the at least one module bay (64) and operating under the control of the controller (34). A low-maintenance piston pump module (90, 240, 340) for use with the chemical dispenser (14) is also disclosed.
Patent WO-2021011411-A1 (WO)
Inventor: THOMPSON CHASE
IPC: A61M25/00
Filed: 2020-07-10
Abstract: A tracking system configured to track the movement of the medical device. The medical device can include a proximal portion that has a magnetic element attached thereto. The system can include a console with a display, and a TLS sensor. The TLS sensor can be disposed on a surface of the patient and can include an LED array. The LED array can indicate a proximity of the medical device to the TLS sensor. The LED array can provide different colors and/or project images to display information regarding the location, orientation, distance, or depth of the medical device. The display can be disposed on an upper surface of the TLS sensor and can be configured to show an image of the medical device disposed therebelow, along with additional information and imagery, thus providing a standalone unit.
Patent WO-2021026115-A1 (WO)
Inventor: ULAM DEVIN W
IPC: G06Q10/04
Filed: 2020-08-04
Abstract: A computer-implemented method of optimizing an industrial process includes comparing current environmental condition data to historic environment condition data for at least one day preceding a specified day. The method also includes determining a visual state from a plurality of visual states for the at least one day based on the comparison between the current environmental condition data and the historic environment condition data. The method further includes generating a calendar interface comprising a plurality of days preceding the specified day and corresponding to a plurality of visual representations. The method further includes generating a graphical user interface comprising historical data for at least one type of industrial process.
Patent WO-2021041014-A1 (WO)
Inventor: MCCAULEY NATHAN P
IPC: G06F21/40
Filed: 2020-08-10
Abstract: Methods, systems, and apparatus for risk mitigation for a cryptoasset custodial system include transmitting an endorsement request for a cryptoasset transaction to a user device configured to cause the user device to prompt a user to endorse the cryptoasset transaction. Multiple data points are collected from mobile devices associated with the user. The data points indicate an identity of the user. A cryptographic endorsement of the cryptoasset transaction is received from the user device. A graphical visualization including a risk metric is generated based on the data points. The risk metric indicates a risk of accepting the cryptographic endorsement from the user device. Generating the graphical visualization includes determining whether the plurality of data points matches expected values.
Patent WO-2021030633-A1 (WO)
Inventor: HASSAN SAMUEL CLEMENT
IPC: A61K38/20
Filed: 2020-08-13
Abstract: Provided herein are engineered IL2 polypeptides and fusion proteins thereof. Also provided are methods of modulating an immune response by administering an engineered IL2 polypeptide or a fusion protein thereof. The engineered IL2 polypeptides and fusion proteins thereof demonstrate increased binding to IL2Rβ, decreased binding to IL2Rα, or both.
Patent WO-2021086486-A1 (WO)
Inventor: MIXTER JOHN E
IPC: G06N3/063
Filed: 2020-08-28
Abstract: An artificial neural network is implemented via an instruction stream. A header of the instruction stream and a format for instructions in the instruction stream are defined. The format includes an opcode, an address, and data. The instruction stream is created using the header, the opcode, the address, and the data. The artificial neural network is implemented by providing the instruction stream to a computer processor for execution of the instruction stream.
Patent WO-2021061561-A1 (WO)
Title: Vehicle glazing
Inventor: LEONARD LINDA ANNE
IPC: B60J3/00
Filed: 2020-09-21
Abstract: A vehicle glazing according to this disclosure comprises a glass sheet or glass sheets, and an ultraviolet light sensor for sensing an amount of ultraviolet light transmitted through the glass sheet or sheets. The ultraviolet light sensor may be provided on a glass surface as to receive light transmitted through at least one of the glass sheets and may be formed with an indicator showing information of the interior UV status.
Patent WO-2021091663-A1 (WO)
Inventor: JENKINS KURT ALLEN
IPC: G02B27/01
Filed: 2020-10-14
Abstract: A near-eye optical element includes light sources arranged with an illumination layer. The light sources are angled to direct light from the light sources to illuminate an ocular region.
Patent WO-2021076765-A1 (WO)
Title: Outil chirurgical à tubes d'arbre emboîtés
Inventor: MOREIRA RIDSDALE DAVID I
IPC: A61B34/30
Filed: 2020-10-15
Abstract: Instrument chirurgical comprenant un châssis, un tube externe ayant une extrémité proximale couplée de manière fonctionnelle au châssis, et un tube interne s'étendant à l'intérieur du tube externe. Le tube interne a une extrémité proximale couplée de manière fonctionnelle au châssis pour permettre un mouvement coulissant du tube interne par rapport au tube externe en réponse à une force appliquée à une extrémité distale du tube interne, et de telle sorte que la force de frottement appliquée à une surface externe du tube externe n'est pas appliquée à l'élément interne.
Patent WO-2021081106-A1 (WO)
Title: Methods for producing and using alkaline aqueous ferric iron solutions
Inventor: LITTLE CHARLES DEANE
IPC: B01D53/52
Filed: 2020-10-21
Abstract: Methods for removing reduced sulfur compounds, such as hydrogen sulfide, from fluids employing a ferric iron salt that exhibits unusually high solubility in aqueous, alkaline solutions and has strong affinity for capture and oxidation of reduced sulfur compounds. Alkaline aqueous ferric iron salt and solutions thereof useful for removing reduced sulfur compounds from fluids and various methods of production of such salts and solutions. In addition, methods of regenerating the alkaline aqueous ferric iron salt solutions after capture of hydrogen sulfide or other reduced sulfur compounds, generally by exposure to oxygen in air. The alkali metal carbonate salt preferably comprises potassium carbonate and/or potassium bicarbonate. The alkaline aqueous ferric iron salt solutions generally comprise ferric ions, potassium ions, carbonate ions, and bicarbonate ions, optionally with one or more organic additives. In addition, aqueous-soluble, ferric iron salts and ferric iron containing solids prepared by removal of aqueous medium from solutions herein.
Patent WO-2021101913-A1 (WO)
Inventor: SOUSA WESTON
IPC: G03F1/84
Filed: 2020-11-17
Abstract: A reticle inspection system may include two or more inspection tools to generate two or more sets of inspection images for characterizing a reticle, where the two or more inspection tools include at least one reticle inspection tool providing inspection images of the reticle. The reticle inspection system may further include a controller to correlate data from the two or more sets of inspection images to positions on the reticle, detect one or more defects of interest on the reticle with the correlated data as inputs to a multi-input defect detection model, and output defect data associated with the defects of interest.
Patent WO-2021113443-A1 (WO)
Title: Two-pass end to end speech recognition
Inventor: SAINATH TARA C
IPC: G06N3/04
Filed: 2020-12-03
Abstract: Two-pass automatic speech recognition (ASR) models can be used to perform streaming on-device ASR to generate a text representation of an utterance captured in audio data. Various implementations include a first-pass portion of the ASR model used to generate streaming candidate recognition(s) of an utterance captured in audio data. For example, the first-pass portion can include a recurrent neural network transformer (RNN-T) decoder. Various implementations include a second-pass portion of the ASR model used to revise the streaming candidate recognition(s) of the utterance and generate a text representation of the utterance. For example, the second-pass portion can include a listen attend spell (LAS) decoder. Various implementations include a shared encoder shared between the RNN-T decoder and the LAS decoder.
Patent WO-2021113470-A1 (WO)
Title: Catalyseur encapsulé pour systèmes d'organopolysiloxane à une partie et procédés associés
Inventor: LIU JIANHUA
IPC: B01J37/03
Filed: 2020-12-03
Abstract: L'invention concerne une particule ayant un catalyseur de groupe platine qui est complètement encapsulé dans un polymère thermoplastique. La particule peut être utilisée dans une composition d'organopolysiloxane durcissable qui comprend également des composants d'organopolysiloxane.
Patent WO-2021127480-A1 (WO)
Title: Synthetic triterpenoids with nitrogen-based substituents at c-17 and methods of use thereof
Inventor: BENDER CHRISTOPHER
IPC: A61P35/00
Filed: 2020-12-18
Abstract: In some aspects, the present disclosure provides compounds of the formula: (I) and (II), wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders associated with inflammation and cancer.
Patent WO-2021133866-A1 (WO)
Inventor: GILES FRANCIS
IPC: A61K31/357
Filed: 2020-12-23
Abstract: The present invention provides methods of treating myelofibrosis in a patient by administering to the patient a therapeutically effective amount of a 08Κ-3β inhibitor such as 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[l,3]dioxolo[4,5-f]indol-7-yl)pynOle-2,5-dione, or a pharmaceutically acceptable salt thereof, optionally in combination with a therapeutically effective amount of a JAK inhibitor such as ruxolitinib, or a pharmaceutically acceptable salt thereof.
Patent WO-2021142274-A1 (WO)
Title: Systems and methods for reducing forced application termination
Inventor: HANDS BEN
IPC: G06F9/48
Filed: 2021-01-08
Abstract: The disclosed computer-implemented method may include detecting an application running in a background state on a client device. The method may also include collecting state data about a current state of the client device. Additionally, the method may include determining, by applying a machine learning model to the collected state data, that a likelihood of forcible termination of the application within a predetermined timeframe exceeds a threshold. Furthermore, the method may include reducing a computing resource footprint of the application on the client device to reduce the likelihood of forcible termination of the application. Various other methods, systems, and computer-readable media are also disclosed.
Patent WO-2021154506-A1 (WO)
Title: Integrated intravenous catheter having a side port for facilitating blood draw
Inventor: NAIDU JITHENDRA KUMAR SATHYANARAYANA
IPC: A61B5/154
Filed: 2021-01-14
Abstract: Integrated IV catheters can have a side port that facilities drawing blood. The side port provides separate fluid pathways for drawing blood and for injecting fluids via an extension set. The side port can be configured to allow the extension set to be primed while a blood sample is collected. In this way, the collection of a blood sample at the time of catheter insertion is facilitated.
Patent WO-2021155241-A1 (WO)
Title: Significance modeling of clonal-level absence of target variants
Inventor: ARTSIOMENKA ALIAKSANDR
IPC: G16B20/20
Filed: 2021-01-29
Abstract: Provided herein are methods of making negative predictions. In some aspects, methods of determining that a first target nucleic acid variant is absent at a first genetic locus in a cell-free nucleic acid (cfNA) sample obtained from a subject having a given cancer type at least partially using a computer are provided. Certain of these methods include determining that the first target nucleic acid variant is not detected in the cfNA sample obtained from the subject, generating, by the computer, at least one tumor fraction based value; generating, by the computer, at least one mutual exclusivity value; and determining that the first target nucleic acid variant is absent at the first genetic locus in the cfNA sample using the tumor fraction based value and/or the mutual exclusivity value. Additional methods and related systems and computer readable media are also provided.
Patent WO-2021163077-A1 (WO)
Title: Active alignment of optical die to optical substrates
Inventor: SYNDER BRADLEY
IPC: G02B6/12
Filed: 2021-02-09
Abstract: An assembly system for assembling an optical die to an optical substrate includes test equipment configured to test optical couplers formed between the optical die and the optical substrate. The assembly system is configured to adjust an alignment of the optical die relative to the optical substrate until the optical couplers meet a performance metric. After the performance metric is met the optical die is permanently attached to the optical substrate.
Patent WO-2021167887-A1 (WO)
Inventor: MATHIAS RICHARD
IPC: A47L13/16
Filed: 2021-02-16
Abstract: L'invention concerne un dispositif de nettoyage qui peut être fixé de manière amovible à une tête de remplacement. La tête de remplacement comprend un tampon qui est fixé au côté inférieur d'un élément de fixation, et qui est en contact avec le sol pendant le nettoyage. Le dispositif de nettoyage est fixé de manière amovible à l'élément de fixation de la tête de remplacement en abaissant le corps de dispositif de nettoyage verticalement vers le bas sur la tête de remplacement jusqu'à ce qu'une connexion mécanique soit obtenue.
Patent WO-2021168046-A1 (WO)
Title: C-v2x message processing timeline adaption based on contouring of remote vehicles and available delay budget
Inventor: DAS SOUMYA
IPC: H04W4/46
Filed: 2021-02-18
Abstract: Techniques described herein provide for filtering and prioritizing incoming messages, which can help reduce and smooth out the processing load on components used to process the incoming messages. Filtering techniques may comprise identifying a subset of nearby vehicles from which messages are to be processed, and further calculating remaining delay budgets with regard to the messages to prioritize them for processing. Different techniques for determining a subset of nearby vehicles can be used, and/or remaining delay budgets may be calculated and/or communicated in different ways.
Patent WO-2021211261-A1 (WO)
Title: Local dimming in a device
Inventor: SEARS JASMINE SORIA
IPC: G02B27/01
Filed: 2021-03-21
Abstract: An optical assembly is configured to receive visible scene light at a backside of the optical assembly and to direct the visible scene light on an optical path toward the eyeward side. The optical assembly also includes a dimming layer disposed on the optical path, where the dimming layer includes a photochromic material that is configured to darken in response to exposure to a range of light wavelengths. An activation layer, included in the optical assembly, is also disposed on the optical path and includes an in-field dimmer. The in-field dimmer is configured to selectively emit an activation light within the range of light wavelengths to activate a darkening of a region of the dimming layer to dim the visible scene light within the region.
Patent WO-2021207223-A1 (WO)
Inventor: GABRIELE PETER D
IPC: C08G63/47
Filed: 2021-04-06
Abstract: A water-mediated process prepares a polymeric (meth)acrylation composition. In some embodiments, the process includes providing a stabilized aqueous solution including a (meth)acrylation component and a polyol monomer in a vessel under an inert atmosphere and adding a diacid monomer to the vessel under the inert atmosphere. In some embodiments, the process includes providing a stabilized aqueous solution including a (meth)acrylation component and a copolymer of a polyol monomer and a diacid monomer in a vessel under an inert atmosphere. The process further includes heating and removing water from the vessel under the inert atmosphere to produce the polymeric (meth)acrylation composition. The polymeric (meth)acrylation composition includes a (meth)acrylation polyester copolymer of the diacid monomer and the polyol monomer with the (meth)acrylation component conjugated to the (meth)acrylation polyester copolymer. In some embodiments, the polymeric (meth)acrylation composition is free of mineral acid and free of cytotoxic solvents, catalysts, and scavengers.
Patent WO-2021216316-A1 (WO)
Inventor: CHEN HAIXING
IPC: C03C17/00
Filed: 2021-04-13
Abstract: A glass article is provided (and methods of making the same) that includes: a glass substrate comprising a thickness and a first primary surface; and a porosity-graded layer that extends from the first primary surface of the substrate to a first depth within the substrate. The first depth is from about 250 nm to about 3000 nm. The porosity-graded layer comprises a plurality of pores having an average pore size from about 5 nm to 100 nm. The article comprises a single-side average reflectance of less than 9% at an incident angle of 60 degrees across a spectrum from 350 nm to 2000 nm. Further, the porosity-graded layer comprises a surface porosity at the first primary surface and a bulk porosity at the first depth, the surface porosity greater than the bulk porosity.
Patent WO-2021222656-A1 (WO)
Inventor: VAN BAALEN MARINUS WILLEM
IPC: G06N3/063
Filed: 2021-04-29
Abstract: Various embodiments include methods and devices for joint mixed-precision quantization and structured pruning. Embodiments may include determining whether a plurality of gates of quantization and pruning gates are selected for combination, and in response to determining that the plurality of gates are selected for combination, iteratively for each successive gate of the plurality of gates selected for combination quantizing a residual error of a quantized tensor to a scale of a next bit-width producing a residual error quantized tensor in which the next bit-width increases for each successive iteration, and adding the quantized tensor and the residual error quantized tensor producing a next quantized tensor in which the next quantized tensor has the next bit-width, and in which the next quantized tensor is the quantized tensor for a successive iteration.
Patent WO-2021226016-A1 (WO)
Title: Multiple patterning with organometallic photopatternable layers with intermediate freeze steps
Inventor: DE SCHEPPER PETER
IPC: H01L21/308
Filed: 2021-05-04
Abstract: Multiple patterning approaches using radiation sensitive organometallic materials is described. In particular, multiple patterning approaches can be used to provide distinct multiple patterns of organometallic material on a hardmask or other substrate through a sequential approach that leads to a final pattern. The multiple patterning approach may proceed via sequential lithography steps with multiple organometallic layers and may involve a hardbake freezing after development of each pattern. Use of an organometallic resist with dual tone properties to perform pattern cutting and multiple patterning of a single organometallic layer are described. Corresponding structures are also described.
Patent WO-2021231928-A1 (WO)
Title: A method for treating cancer with an oral dosage form of an fgfr4 inhibitor
Inventor: XIAO JIANJUN
IPC: A61K31/505
Filed: 2021-05-14
Abstract: The present invention relates to pharmaceutical compositions comprising an inhibitor of FGFR4, and methods of cancer therapy using the FGFR4 inhibitor. In particular, described herein are dosages of H3B-6527 with defined pharmacokinetic (PK) profiles that allow the inhibitor to be efficaciously and safely administered to a human subject in need thereof.
Patent WO-2021231959-A1 (WO)
Title: Methods for immunotherapy
Inventor: HEERY CHRISTOPHER
IPC: C07K19/00
Filed: 2021-05-14
Abstract: The present invention encompasses methods for reducing the number of target cells in a subject, such as cancer cells. The methods include administration of genetically-modified human immune cells expressing a chimeric antigen receptor or exogenous T cell receptor, which have specificity for an antigen on the target cells. Administration of the genetically- modified immune cells is preceded by the administration of a tolerance regimen, followed by administration of a lymphodepletion regimen, to improve efficacy of the therapy and persistence of the cells in vivo.
Patent WO-2021252908-A1 (WO)
Title: Robotic cleaner having surface type sensor
Inventor: WOODROW CHAD
IPC: A47L11/40
Filed: 2021-06-11
Abstract: A combination surface type sensor may include a housing including a first receptacle, a second receptacle, a third receptacle, and a fourth receptacle, a first surface type detector disposed within the first receptacle, a second surface type detector disposed within the fourth receptacle, an emitter disposed within the second receptacle, and a drop-off detector disposed within the third receptacle.
Patent WO-2021257647-A1 (WO)
Title: Reference precharge system
Inventor: GUPTA AMIT KUMAR
IPC: H03M1/34
Filed: 2021-06-16
Abstract: A precharge circuit (500) comprises a gain amplifier (510), a comparator (530), a reservoir capacitor (550), a switch (545), a current source (540), and a switching network. The gain amplifier has a gain G1 and receives an input voltage Vrefp (505). The gain amplifier outputs an amplified voltage G1Vrefp to the comparator, which compares G1Vrefp to a voltage across the reservoir capacitor. The comparator outputs a control signal (ϕ2SW) for the switch based on the comparison. The switch couples the current source to the reservoir capacitor. The current from the current source charges the reservoir capacitor. The switching network couples the reservoir capacitor to an output of the precharge circuit during a first operating mode and provides the input voltage Vrefp to the output during a second operating mode.