baber/WOPTO huggingface dataset:
Patent CA-2545060-A1 (CA)
Title: Methods of use of thrombin receptor antagonists
Inventor: CLASBY MARTIN C
IPC: C07D521/00
Filed: 2004-11-09
Abstract: A method of treating a therapeutic condition comprising administering to a mammal in need of such treatment an effective amount of at least one compound of the formulas (I) and (II) or a pharmaceutically acceptable isomer, salt, solvate or co-crystal form thereof, wherein the substituents are as defined in the specification, wherein said therapeutic condition is a cardiovascular or circulatory disease or condition, an inflammatory disease or condition, a respiratory tract or disease or condition, cancer, acute renal failure, astrogliosis, a fibrotic disorder of the liver, kidney, lung or intestinal tract, Alzheimer~s disease, diabetes, diabetic neuropathy, rheumatoid arthritis, neurodegenerative disease, neurotoxic disease, systemic lupus erythematosus, multiple sclerosis, osteoporosis, glaucoma, macular degeneration, psoriasis, radiation fibrosis, endothelial dysfunction, a wound or a spinal cord injury, or a symptom or result thereof. Combination therapy with other therapeutically effective agents is also disclosed.
Patent CA-2546442-A1 (CA)
Inventor: GALIGURI STEVEN J
IPC: B60R9/00
Filed: 2003-11-21
Abstract: Dans un mode de réalisation, la présente invention a trait à un appareil qui peut être fixé de manière sélective à un véhicule, pour le transport d'un dispositif et le positionnement du dispositif dans une orientation qui permet l'accès au véhicule. L'appareil peut comporter un bras de support définissant un axe longitudinal de bras de support, dans lequel le bras de support, comporte un trou de collet d'attelage. L'appareil peut également comporter un bras oscillant primaire définissant un axe longitudinal de bras oscillant primaire. L'appareil peut en outre comporter un ensemble d'articulation primaire couplé au bras de support et au bras oscillant.
Patent CA-2547140-A1 (CA)
Inventor: DEFREES SHAWN
IPC: C07K14/505
Filed: 2004-11-24
Abstract: The present invention provides conjugates between erythropoietin and PEG  moieties. The conjugates are linked via an intact glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
Patent CA-2549215-A1 (CA)
Inventor: MALM HOWARD
IPC: F02B33/00
Filed: 2006-06-01
Abstract: A control system for a turbo charged natural gas engine. A butterfly valve used for fuel control upstream of a carburetor provides non-linear flow response during opening and closing and a flow compensator compensates for the non-linear response. A throttle valve position sensor acts in association with a controller which compares the throttle valve position signal with a predetermined set point and thereby opens or closes the waste gate of the turbo charger which affects oxygen content in the exhaust. A  compensator for a throttle valve used with electronic engine controllers is also provided.
Patent CA-2558083-A1 (CA)
Inventor: FROHBERG CLAUS
IPC: C12N9/12
Filed: 2005-03-04
Abstract: The present invention relates to a method for identifying proteins involved in the phosphorylation of starch and nucleic acids which code for such proteins.  The present invention further relates to plant cells and plants which exhibit an altered activity of a protein which can be identified using the method according to the invention. Plant cells and plants of this type synthesise a modified starch. The present invention therefore also relates to the starch synthesised by the plant cells and plants according to the invention as well as to methods for the manufacture of this starch and to the manufacture of starch derivatives of this modified starch.
Patent CA-2558944-A1 (CA)
Title: Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
Inventor: BODOR NICHOLAS S
IPC: A61P27/02
Filed: 2004-06-17
Abstract: Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17.alpha.-alkoxycarbonyloxy-11.beta.-hydroxyandrost-4-en-3-one-17.beta.-carboxylate type and the corresponding .DELTA.1,4-compounds are described. The enhancing agents have the formula: (II) wherein R is H or C1-C4 alkyl; Z1 is carbonyl or .beta.-hydroxymethylene; X1 is -O- or -S-; R5 is -OH, -OR6, -OCOOR6 or -OCOR7 wherein R6 is C1-C4 alkyl and R7 is C1-C4 alkyl, fluoromethyl or chloromethyl; and the dotted line in ring A indicates that the 1,2-linkage is saturated or unsaturated; with the proviso that when R is C1-C4 alkyl, then R5 is -OH.
Patent CA-2560500-A1 (CA)
Title: Folded oven rack
Inventor: BROOKS JEAN GILLIS
IPC: F24C15/16
Filed: 2006-09-01
Abstract: A supporting rack includes arranged rods arranged to form a planar grid pattern and connection means to allow for modification in the overall space occupied by the rack, to allow the folding thereof. The connection means comprises a support member connected at one end to a first portion of the rack and pivotally connected at another end to a plate portion integrally connected underneath a second portion of the rack, whereby the first portion of the rack can be pivoted downwardly, so as enable the folding thereof. Upward pivoting movement of the first portion of the rack is restricted by a downwardly depending rest member which is connected underneath the second portion of the rack.
Patent CA-2561278-A1 (CA)
Title: Embedded planar antenna and pertaining tuning method
Inventor: MIERKE FRANK
IPC: H01Q1/40
Filed: 2005-03-24
Abstract: The invention relates to an improved planar antenna, especially a patch antenna (1), which comprises an electrically conductive ground plane (2); a first dielectric substrate layer (3) arranged on said ground plane (2) and having a first relative permittivity; at least one electrically conductive effective area (4) arranged on the first dielectric substrate layer (3) and electrically connected to one end (5a) of an electrically conductive feed line (5); at least one second dielectric substrate layer (6) arranged on the effective area (4) and having a second relative permittivity; whereby the second relative permittivity is larger or equal the first relative permittivity.
Patent CA-2561364-A1 (CA)
Inventor: LIEBERBURG IVAN
IPC: A61K31/52
Filed: 2005-03-30
Abstract: This invention relates generally to a use of a medicament to treat inflammatory bowel diseases (IBD), asthma, Crohn's Disease (CD), multiple sclerosis (MS), rheumatoid arthritis (RA), graft versus host disease (GVHD), host versus graft disease, and various spondyloarthropathies, comprising administering a steroid-sparing effective amount of an immunoglobulin or to a patient in need thereof. The invention also relates generally to combination therapies for the treatment of these conditions.
Patent CA-2563048-A1 (CA)
Inventor: KATSUKI AKIO
IPC: E02D5/80
Filed: 2005-03-30
Abstract: A method for pre-attaching-fixing an anchor bolt, and a method and a device for excavating an anchor bolt burying hole. The method for pre-attaching-fixing the anchor bolt with sufficient strength in a construction surface without lowering strength even if an existing reinforcement arrangement is present comprises the steps of excavating a first burying hole for burying the anchor bolt in the construction surface, excavating a second burying hole at the tip of the first burying hole by bending from the tip of the first burying hole, and burying the anchor bolt bent in the middle part thereof in these first and second burying holes.
Patent CA-2563244-A1 (CA)
Title: Improved tire installation and removal tool
Inventor: VAN TRAN LOI
IPC: B60C25/02
Filed: 2006-10-11
Abstract: A tool is provided for assistance in removing and installing tires on wheel rims. The tool can be provided with a handle having a tool head disposed at each end. Each tool head is designed to fit between a tire bead and an associated wheel rim so that when the handle is levered, a force is applied to the bead and rim that moves the bead over the rim. Each tool head has a substantially flat portion which can be easily fit between opposing tire and wheel rim surfaces. One tool head has a slightly hooked distal tip to enable axial engagement with a flange of the wheel rim, and thus can be used either for installing a tire on a rim or for removing a tire from the rim. Another tool head has a protrusion disposed near the tool midpoint to engage a flange of the wheel rim. The protrusion can be a roller member having a pin axis perpendicular to an axis of the tool handle. This roller can be fabricated from a soft polymer or rubber material so that the tool will not damage soft-metal wheel rims such as aluminum. The handle can have a pronounced curvature that allows a portion of the handle body to be received within the cavity formed by the wheel rim. This curvature allows for a greater range of motion of the handle, thus providing the user improved leverage as compared to prior tools. The tool heads may be permanently attached to the handle, or they may be removable to allow the user to customize the tool to the desired application.
Patent CA-2567092-A1 (CA)
Inventor: COWAN KENNETH MICHAEL
IPC: E21B33/13
Filed: 2005-06-02
Abstract: Disclosed is a composition comprising a chemical formulation useful for creating geosynthetic composites in-situ that includes a melamine-formaldehyde resin in a non-aqueous drilling fluid.
Patent CA-2568117-A1 (CA)
Title: Conversion from note-based audio format to pcm-based audio format
Inventor: BYLSMA RODNEY
IPC: G10H5/00
Filed: 2006-11-14
Abstract: A system and method for converting a note-based audio object to a Pulse Code Modulated (PCM) audio format is disclosed. An electronic communication device includes a memory containing a note-based audio object and lookup table containing trigonometric function evaluations. The note-based audio object contains note frequency information. The note--based audio object is converted to a PCM stream by generating PCM code words for each sample point in the PCM stream based upon the note frequency information. The PCM code words are determined based upon selection of one or more of the trigonometric function evaluations within the look-up table. A speaker outputs audio based upon the PCM formatted stream.
Patent CA-2568825-A1 (CA)
Inventor: ZHAO JONATHON Z
IPC: A61K31/436
Filed: 2006-11-24
Abstract: The present invention relates to nano- and/or micro-particulate formulations that can be locally injected into arterial walls at or near target sites to achieve a prolonged and sufficiently high local concentration of at least one pharmacologically active agent for treatment of vascular diseases, such as, for example, restenosis, vulnerable plaque, aneurysm, and stroke.  Specifically, each formulation comprises biocompatible and biodegradable nano-particles and/or micro-particles loaded with the pharmacologically active agent and d-alpha-tocopheryl polyethylene glycol 1000 succinate (vitamin E  TPGS). The formulations can be formed by a solvent evaporation/extraction process or a supercritical CO2 extraction process that uses vitamin E TPGS  as an emulsifier. Further, vitamin E TPGS can be used as a stabilizer for the pharmacologically active agent in the final drug formulation, as well as a release modulation to control release of the pharmacologically active agent.
Patent CA-2569176-A1 (CA)
Inventor: KIM IN KYU
IPC: B60S1/40
Filed: 2006-11-29
Abstract: The present invention relates to a wiper blade mounted to a wiper apparatus for a vehicle to wipe a windshield. An object of the present invention is to provide a wiper blade which can be more easily assembled and manufactured by forming a connector integrally with a wiper frame. According to the present invention for achieving the object, there is provided a wiper blade coupled to a wiper arm of a vehicle to wipe a windshield, comprising a wiper strip in contact with the windshield; a wiper frame curved along its lengthwise direction and having elasticity to bring the wiper strip into contact with the windshield; and a connector formed integrally with the wiper frame and coupled with the wiper arm.
Patent CA-2570257-A1 (CA)
Title: Polymer films
Inventor: SELLERGREN BOERJE
IPC: C08F265/06
Filed: 2005-07-01
Abstract: This invention relates to a non-supported (or free standing) cross linked polymer film obtainable by initiating the polymerization of one or several monomers at an interphase. The interphase may be between two immiscible liquids or at a liquid-gas, solid-gas or solid-liquid interphase. The polymer may be used to facilitate chemical reactions, for separation of substances, as a chromatographic stationary phase, as an adsorbent, in sensors or actuators.  It may also be used for drug delivery, as a responsive valve or in artificial muscles. The invention also relates to a method for producing thin film polymers, wherein controlled radical polymerization (CRP) is used to produce a thin film cross-linked polymer at an interface where one of the phases (liquid, solid or gas) can be removed after polymerization and be replaced with another phase (liquid, solid or gas).
Patent CA-2570262-A1 (CA)
Inventor: ROTH KEVIN JAY
IPC: B41M5/52
Filed: 2005-06-08
Abstract: A product and a process for the preparation of a precipitated calcium carbonate (PCC) and an ink jet recording paper, incorporating the precipitated calcium carbonate is disclosed. The precipitated calcium carbonate is dewatered and comminuted in the presence of an amphoteric and/or anionic dispersant to produce a high solids PCC composition. When used in coating formulations the PCC has a surface morphology and chemistry that enhances the printability of ink jet paper. Ink jet recording paper incorporating the PCC  of the present teachings has reduced ink feathering and spreading as well as improved optical density, dry time, and water fastness.
Patent CA-2572655-A1 (CA)
Title: Method for the production of snap disks
Inventor: WURMB ALFRED
IPC: H01H11/00
Filed: 2005-07-05
Abstract: The invention relates to a method for stabilizing the two snap temperatures of snap elements made of thermostatic bimetal. According to the method, the mechanical steps are not interrupted by the required thermal treatment such that the embossed snap elements are pressed flat times at a great aging temperature. The snap elements remain in the automatic production device during the process and can then be further processed in the automatic device.
Patent CA-2572811-A1 (CA)
Title: Method for producing 3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1h)-one
Inventor: RALL WERNER
IPC: C07D243/04
Filed: 2005-07-16
Abstract: The invention relates to a method for producing a compound 3-(4-Piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)-on of formula (I), wherein said compound is a structural element of CGRP-antagonists which are particularly suitable for the oral migraine treatment.
Patent CA-2572956-A1 (CA)
Title: Methods and systems for automating inventory and dispatch procedures at a staging area
Inventor: OLSEN JOHN A III
IPC: G06Q10/00
Filed: 2005-03-17
Abstract: Methods and systems disclosed herein are used to automate inventory and dispatch procedures at a staging area by automatically detecting the arrival or departure of delivery vehicles (16), container devices (18) and other such items. Detection of these items is facilitated by the use of automatic identification tags (14), and other such devices, that are physically associated with each such item. According to one aspect of the invention, the detection of inbound vehicles and related container devices (18) triggers a series of automated communications that facilitate the dispatch of such items within the staging area. Additionally, when a delivery vehicle or container device (18) departs, the system can be configured to check the tag (14) or device associated with each such item so as to confirm that the correct container device(s) (18) are associated with the correct outbound delivery vehicle (16). The system further provides a method of tracking inventories of such items in real time.
Patent CA-2574550-A1 (CA)
Title: Method for drying a gas and device applied thereby
Inventor: VANDERSTRAETEN BART ETIENNE AG
IPC: F04B39/16
Filed: 2005-07-28
Abstract: Method for drying a gas from a compressor (1) by means of a drier (2) of the type which consists of a pressure tank (3) with a drying zone (4) and a regeneration zone (5), with a rotor (6) which is composed of a drying element (7) in which has been provided an adsorption and/or absorption medium (8) which is alternately put through the drying zone (4) and the regeneration zone (5), characterised in that at a low load or zero load, the inlet of the regeneration zone (5) is connected to the user network (12) via a regeneration pipe (27), and in that the outlet of the regeneration zone (5) is connected to the atmosphere.
Patent CA-2575980-A1 (CA)
Title: Combination of a selective noradrenaline reuptake inhibitor and a pdev inhibitor
Inventor: HUGHES BERNADETTE
IPC: A61P29/00
Filed: 2005-07-29
Abstract: The present invention relates to a combination of a selective noradrenaline reuptake inhibitor (NRI) and a phosphodiesterase type 5 (PDEV) inhibitor. Such a combination is particularly useful in the treatment of pain.
Patent CA-2576279-A1 (CA)
Title: Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
Inventor: LETTS L GORDON
IPC: C07C229/28
Filed: 2005-11-08
Abstract: The invention describes novel nitrosated and/or nitrosylated compounds or pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated compound, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides novel compositions and kits comprising at least one compound of the invention, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor compound and/or at least one therapeutic agent. The invention also provides methods for treating ophthalmic disorders. The nitrosated and/or nitrosylated compounds are preferably nitrosated and/or nitrosylated (3-adrenergic antagonists and nitrosated and/or nitrosylated angiotensin-converting enzyme (ACE) inhibitors.
Patent CA-2576467-A1 (CA)
Inventor: WEISSMAN HAIM
IPC: H04B17/00
Filed: 2005-08-03
Abstract: A method for estimating a size of reverse link resources provided by a base-station transceiver system (BTS), including performing respective first, second, and third measurements of first, second, and third signal strengths received at the BTS. The method also includes comparing the first measurement with the second measurement so as to determine an initial minimum signal strength, and adding at a predetermined time an aging value to the initial minimum signal strength so as to form an updated minimum signal strength. The method further includes forming a comparison between the updated minimum signal strength and the third measurement, determining from the comparison a minimum of the updated minimum signal strength and the third measurement to be a minimum received signal strength, and determining the size of the reverse link resources provided by the BTS in response to the minimum received signal strength.
Patent CA-2578034-A1 (CA)
Title: Vehicle door provided with a joint
Inventor: JUNG JEROME
IPC: B61D19/02
Filed: 2005-08-26
Abstract: The invention relates to a railway vehicle including a body defining a wall in which an access passage is embodied, at least one closing sliding door, a sealing joint carried by the door and applicable to the wall when said door in a closed position. Said wall includes a panel provided with a generally cylindrical envelop and a seat which is protruded with respect to said panel and defines a bearing surface for supporting the joint only when the door is in the closed position, wherein said bearing surface of a supporting element extends along a profile substantially identical to the joint profile and said joint profile extends transversely with respect to the door displacement direction.
Patent CA-2578676-A1 (CA)
Title: Boilerless steaming oven and method
Inventor: SALTENIS VICTOR D
IPC: F24C13/00
Filed: 2007-02-15
Abstract: A steaming oven having a clad plate bottom. The stainless steel clad material constitutes the bottom of the boiling water reservoir in the oven chamber. The stainless steel clad material is composed of a thin layer of stainless material clad to a thicker plate of base, heat conducting metal like steel, copper or aluminum.
Patent CA-2585334-A1 (CA)
Title: Indole derivatives useful as progesterone receptor modulators
Inventor: SUI ZHIHUA
IPC: A61P5/24
Filed: 2005-10-21
Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding.  Additional uses of the invention include stimulation of food intake.
Patent CA-2586250-A1 (CA)
Title: Compositions for treating respiratory viral infections and their use
Inventor: WOODLE MARTIN C
IPC: C12N15/85
Filed: 2005-11-04
Abstract: The invention provides siRNA compositions that interfere with viral replication in respiratory viral infections, including respiratory syncytial virus and avian influenza A, including the H5N1 strain. The invention further provides uses of the siRNA compositions to inhibit expression of viral genes in respiratory virus-infected cells, and to uses in the treatment of respiratory virus infections in a subject. Generally the invention provides polynucleotide that includes a first nucleotide sequence of 15 to 30 bases that targets the genome of a respiratory syncytial virus or an influenza A  virus, a complement thereof, a double stranded polynucleotide or a hairpin polynucleotide. Additionally the invention provides vectors, cells and pharmaceutical compositions containing siRNA sequences.
Patent CA-2586643-A1 (CA)
Title: Tampon applicator
Inventor: KARAPASHA NANCY
IPC: A61F13/26
Filed: 2005-11-18
Abstract: A tampon applicator having an outer member adapted to house a tampon and receive an inner member. The inner member has a first end and a second end.  The first end is spaced a first distance from a first longitudinal protrusion.  The second end is spaced a second distance from a second longitudinal protrusion.
Patent CA-2587153-A1 (CA)
Title: Inhibitors of 11-.beta. hydroxyl steroid dehydrogenase type 1 and methods of using the same
Inventor: YAO WENQING
IPC: A61K31/4747
Filed: 2005-11-17
Abstract: The present invention relates to inhibitors of 11-.beta. hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-.beta. hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.