baber/WOPTO huggingface dataset:
Patent EP-0625197-B1 (EP)
Inventor: HANSSON LENNART
IPC: C07K14/47
Filed: 1993-01-25
Granted: 2002-12-04
Abstract: The present invention relates to an expression system comprising a DNA sequence encoding a polypeptide which ha a biological activity of human kappa-casein, the system comprising a 5'-flanking sequence capable of mediating expression of said DNA sequence. In preferred embodiments the 5'-flanking sequence is from a milk protein gene of a mammal such as a casein gene or whey acidic protein (WAP) gene and the DNA sequence contains at least one intron sequence. The invention further relates to DNA sequences, replicable expression vectors and cells harboring said vectors, recombinant polypeptide e.g. in glycosylated form, and milk, infant formula or nutrient supplement comprising recombinant polypeptide. The invention also relates to a method for producing a transgenic non-human mammal comprising injecting an expression system as defined above and optionally a further DNA encoding beta-casein or an analog, variant or subsequence thereof into a fertilized egg or a cell of an embryo of a mammal so as to incorporate the expression system into the germline of the mammal and developing the resulting injected fertilized egg or embryo into an adult female mammal. In one embodiment, the endogenous polypeptide expressing capability of the mammal is destroyed and/or replaced with the expression system defined above. The invention further relates to a transgenic non-human mammal such as a mouse, rat, rabbit, goat, sheep, pig, lama, camel or bovine species whose germ cells a somatic cells contain a DNA sequence as defined above as a result of chromosomal incorporation into the non-human mammalian genome, or into the genome of an ancestor of said non-human mammal.
Patent EP-0620785-B1 (EP)
Inventor: FROGGATT JAMES ROGER
IPC: C09D157/08
Filed: 1992-12-30
Granted: 1995-10-18
Abstract: A method of protecting machine-readable markings on the surfaces of articles consisting in applying to the machine-readable markings a thin layer of an amorphous fluoropolymer, which may be, i.a., a copolymer of perfluoro(1,3-dioxole) or of perfluoro(2,2-dimethyl-1,3-dioxole) with a fluoromonomer selected from a specifically recited group, especially, with tetrafluroethylene; or a cyclic aliphatic homopolymer in which the repeating unit contains an aliphatic ring of 5-9 members, at least two of the ring members being carbon atoms independently substituted either by fluorine atoms or by perfluoromethyl groups, at most two of the ring atoms being oxygen atoms, the remaining portions of the repeating units, when present, being perfluoromethylene groups.
Patent EP-0626094-B1 (EP)
Inventor: SCHOETTLE KLAUS
IPC: G11B23/087
Filed: 1993-02-04
Granted: 1996-06-19
Abstract: A cassette or a container with a recording medium is fitted with a movable closure for at least one aperture. The closure is in at least two parts, one of which is of plastic and the other of metal, or both may be of plastic. The closure may advantageously be used for all containers with recording media fitted with movable closure components.
Patent EP-0624265-B1 (EP)
Inventor: DOOLITTLE MILES G
IPC: F16H59/10
Filed: 1993-02-03
Granted: 1997-06-11
Abstract: An automatic transmission shifter (10) for a vehicle comprises a unitary glass reinforced nylon housing (12) open at the bottom and having interconnected, spaced upper (24), side (18, 20) and end walls (22, 30). A slot (28) is formed in bosses (56, 60) are formed in the side walls (18, 20), and integral flanges (38, 44) extend from the side and end walls and incorporate a plurality of spaced apertures (52a, 52b, 52c) for mounting the housing (12) to vehicle structure. A pair of spaced, aligned position control plates (122a, 122b) each comprising a plurality of notches, are formed interiorly on the side walls (18, 20), a plurality of detent notches (120) are formed interiorly on the housing (12) on one of the side walls (20) below the position control plates, and a shift cable access opening (32) is formed in one of the end walls (30). A shift lever assembly (14, 16) including an operating lever (14) extends upwardly through the slot (28). A plastic trunnion (16) mounts the lever (14) and a pivot pin (70) carried by the boss apertures (64) mounts the trunnion (16) for pivotal movement of the lever (14) among a plurality of transmission control positions.
Patent EP-0644845-B1 (EP)
Inventor: THOENS DIETRICH
IPC: B63B25/26
Filed: 1993-06-15
Granted: 1996-04-10
Abstract: L'invention concerne un support latéral démontable de palettisation dans des cales frigorifiques à bord de bateaux, comprenant un panneau mural (1) en tôle présentant un cadre de renfort (2) monté sur son revers, ledit support pouvant être fixé horizontalement, par liaison de force, sur le fond de la cale (3) par un mouvement d'enfoncement vertical, sa face frontale étant disposée parallèlement à l'axe longitudinal du bateau. Ledit support peut prendre appui au moyen de contre-fiches (5) articulées, fixées de manière amovible sur le cadre de renfort (2) dans la moitié supérieure du panneau (1) et fixées à demeure au bordage (6) de la cale du bateau.
Patent EP-0647158-B1 (EP)
Inventor: BOE JEAN-FRANCOIS
IPC: D21C9/10
Filed: 1993-06-21
Granted: 1997-08-20
Abstract: PCT No. PCT/FR93/00613 Sec. 371 Date Feb. 23, 1995 Sec. 102(e) Date Feb. 23, 1995 PCT Filed Jun. 21, 1993 PCT Pub. No. WO94/00234 PCT Pub. Date Jan. 6, 1994A method is provided for delignifying and bleaching a lignocellulose material, wherein an aqueous solution of a redox catalyst and an oxidant is reacted with the material. The catalyst comprises an organometallic cation of the general formula [(1)Mno2Mn(L)]n+, wherein Mn is manganese (III) or (IV) oxide, the two Mn's of this cation may form a pair in a III-III, III-IV or IV-IV oxidative state, n is 2, 3 or 4, O is oxygen, and L is a ligand comprising 4 nitrogen atoms co-ordinating the manganese.
Patent EP-0657429-B1 (EP)
Inventor: ISSHIKI KUNIO
IPC: C07D211/90
Filed: 1993-08-31
Granted: 2001-04-11
Abstract: A (4R)-3-(substituted aminoalkyl)oxycarbonyl-1,4-dihydro-2,6-dimethyl-4-(nitrophenyl)pyridin e-5-carboxylic acid can be produced efficiently by the reaction of a bis(substituted aminoalkyl) 1,4-dihydro-2,6-dimethyl-4-(nitrophenyl)pyridine-3,5- dicarboxylate with a microorganism, or a product of treatment thereof, which can induce asymmetric hydrolysis and belongs to the genus Streptomyces, Paecilomyces, Botryodioplodia, Alternaria or Helminthosporium. This compound is extremely useful as an important intermediate for producing medicines useful for preventing or treating angina pectoris, hypertension and so forth.
Patent EP-0619082-B1 (EP)
Inventor: BROBERG LARS
IPC: A23L13/00
Filed: 1994-03-08
Granted: 1998-06-03
Abstract: A breadcrumb coating for food products which are to be cooked in the oven comprises cereal crumbs, a source of reducing sugars and more than 7% by weight of fats, preferably from 8 to 12% by weight. It is obtained by cooking and extruding the mixture of starting ingredients, grinding and finally drying the ground product.
Patent EP-0628690-B1 (EP)
Inventor: RENZ WALTER
IPC: E05D15/52
Filed: 1994-05-03
Granted: 1996-11-27
Abstract: A corner bearing block (2) for the pivotable and tiltable mounting of a sash/leaf of a window, of a door or the like on a fixed frame (1) comprises a basic plate (6) with screw-on holes (17 to 21), retaining bolts (15 and 16) and a bearing bolt (3) which is mounted rotatably on bearing lugs (7 and 8). Due to the production method, according to the invention, of the basic plate (6) with the bearing lugs (7 and 8), reinforcement borders (23 and 24) are provided in extension of the two bearing lugs (1 and 8). This results in the rear surface (25) of the basic plate (6) having a constant width over the entire length of the corner bearing block (2) and in a rear surface (25), in addition, being essentially planar. This configuration contributes to the considerable reinforcement and thus higher loadability and optimum attachment of the corner bearing block (2) on the frame (1). <IMAGE>
Patent EP-0636737-B1 (EP)
Inventor: GEHLING MATTHIAS DR
IPC: C11D1/38
Filed: 1994-07-06
Granted: 1997-10-29
Abstract: Compositions for removing silicone oil fibre finishes (brightening agents) contain, as essential constituent, a surfactant with cationic groups on the surfactant skeleton; these surfactants can also be amphoteric surfactants or betaine surfactants. These compositions may further contain acids, nonanionic surfactants, water-soluble nonionic polymers and solvents (without halogenated hydrocarbons). The compositions can be used to produce aqueous dispersions in the form of concentrates (as sellable material) or in the form of dilute liquors directly usable in the wash. The compositions are used for removing silicone oil finishes from textile substrates, especially from elastane fibre substrates; for this the compositions are ultimately used in the form of wash liquors.
Patent EP-0611147-B1 (EP)
Inventor: KNEZIC TIMOTHY M
IPC: F25D21/06
Filed: 1994-02-09
Granted: 1998-12-23
Abstract: Two evaporator circuits operate a freezer compartment and a fresh food compartment. The freezer compartment runs typically at 0-2 psig evaporating pressure until satisfied. The refrigerator section that runs typically at 18-22 psig evaporation pressure. A single compressor supplies the refrigerant through the condenser which serves to feed either the high or low pressure evaporators through known expansion devices such a capillary tubes, orifices, expansion valves, etc. Although various circuit options are disclosed, each employ some type of solenoid valve at the capillary tube inlet to determine which evaporator is fed.
Patent EP-0725848-B1 (EP)
Inventor: GIRGIS MIKHAIL M
IPC: D02G3/36
Filed: 1993-11-19
Granted: 2000-06-14
Abstract: A multifilament reinforcing article which comprises fibers coated and impregnated with at least a partially cured, a moisture reduced residue derived from an aqueous chemical coating composition in which the major polymeric component is an elastomeric polymer. The coated and impregnated fibers are bound with a polymeric film-forming binder in the form of a tape, wire or other shape retaining arrangement in which the fibers are substantially parallel.
Patent EP-0674642-B1 (EP)
Inventor: CHEN YUHPYNG LIANG
IPC: A61P1/00
Filed: 1993-11-26
Granted: 2000-08-23
Abstract: A compound of the formula:and the pharmaceutically acceptable acid addition salts thereof, whereinA is NR1R2, CR1R2R11, or C(=CR1R12)R2, NHCR1R2R11, OCR1R2R11, SCR1R2R11, NHNR1R2, CR2R11NHR1, CR2R11OR1, CR2R11SR1 or C(O)R2;wherein the rest of the variables are herein below defined, used for inflammatory disorders.
Patent EP-0703783-B1 (EP)
Inventor: GREY HOWARD M
IPC: C07K7/06
Filed: 1994-03-04
Granted: 2010-05-05
Abstract: The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA-A2.1 allele and inducing T cell activation in T cells restricted by the A2.1 allele. The peptides are useful to elicit an immune response against a desired antigen.
Patent EP-0646132-B1 (EP)
Inventor: REUTTER WERNER
IPC: C12P21/00
Filed: 1994-04-12
Granted: 1999-08-11
Abstract: The invention pertains to new amino sugars (neuraminic acid precursor analogues) and new glycoproteins, methods of preparing them, pharmaceutical agents containing them and their use in stimulating growth and differentiation of human and animal cells of the immune system and in preventing the adhesion of leucocytes, thrombocytes and tumor cells to vascular endothelium cells, also in stimulating the immune system, especially T-lymphocytes, warding off infections and treating weaknesses in the immune system, tumorous illnesses including metastatic processes, infectious diseases (viruses, bacteria, parasites, protozoa) and circulatory failures, especially vascular occlusions and septicemia, in humans and animals.
Patent EP-0696254-B1 (EP)
Inventor: WEIRAUCH HANS-JULIUS
IPC: B65H19/18
Filed: 1994-04-26
Granted: 1997-09-24
Abstract: Un ruban de raccordement (100) comprend une partie de raccordement (1, 2) et une partie de fixation (10', 41), cette dernière (10', 41) étant utilisée pour fixer de manière libérable et autonome le ruban de raccordement (100) sensiblement sur toute la largeur d'un rouleau de matériau en feuille. Une première couche adhésive (2) est prévue pour fixer le bord avant du rouleau au ruban de raccordement (100). La partie de fixation (10', 41) est conçue pour détacher le bord avant et la partie de raccordement (1, 2) du matériau en feuille sous-jacent, de façon à libérer une première surface non-adhésive dudit matériau. Un raccord bout-à-bout ou à recouvrement peut être obtenu par la fixation d'un autre matériau en feuille à la partie de raccordement (1, 2). La partie de fixation (10', 41) comprend de préférence des moyens permettant de séparer cette partie de la partie de raccordement (1, 2), et/ou des moyens (41) permettant de détacher la partie de fixation de la surface de la couche sous-jacente. Selon l'invention, des procédés de production de raccords permanents ou temporaires sont également décrits.
Patent EP-0650454-B1 (EP)
Title: Systeme de convoyeur a bandes superieure et inferieure
Inventor: MENSCH WILLIAM A
IPC: B65G37/00
Filed: 1994-05-16
Granted: 1997-12-03
Abstract: Un convoyeur à bandes selon l'invention (10) comporte des chemins de roulement supérieur (14) et inférieur (18) espacés verticalement, se déplaçant à l'opposé l'un de l'autre et présentant une extrémité d'entrée et une extrémité de sortie (16, 17; 20, 21). Une première série de rouleaux disposés entre l'extrémité de sortie (17) du chemin de roulement supérieur (14) et l'extrémité d'entrée (20) du chemin de roulement inférieur (18) dirige la bande vers le bas, autour d'un premier ensemble d'entraînement (26), en direction de l'extrémité d'entrée (20) du chemin de roulement inférieur (18), le long d'une première section en contrebas (37) du chemin de la courroie, entre le niveau du chemin de roulement inférieur (18), celle-ci remontant ensuite vers l'extrémité d'entrée (20) du chemin inférieur (18), depuis un tendeur statique (38) installé au-dessous du chemin inférieur. Une deuxième série de rouleaux prévus entre l'extrémité de sortie (21) du chemin de roulement inférieur (18) et l'extrémité d'entrée (16) du chemin d'entrée supérieur (14) dirige la bande vers le bas, depuis l'extrémité de sortie du chemin de roulement inférieur (21), le long d'une deuxième section en contrebas (44) du chemin de la bande, au-dessous du niveau du chemin de roulement inférieur, autour d'un deuxième ensemble d'entraînement (48), celle-ci remontant ensuite vers l'extrémité d'entrée (16) du chemin de roulement supérieur (14). Des convoyeurs d'alimentation (105, 106, 107) et d'enlèvement (113, 114, 115) inférieurs prévus respectivement au-dessus des premières (37) et deuxième (44) sections en contrebas du chemin de la bande, convergent et divergent de l'axe d'alignement des extrémités d'entrée (20) et de sortie (21) du chemin de roulement inférieur pour le transfert en ligne d'articles vers et en provenance du chemin de roulement inférieur (18). Les convoyeurs d'alimentation (120) et d'enlèvement (122) supérieurs sont alignés longitudinalement avec les extrémités d'entrée et de sortie du chemin de roulement inférieur.
Patent EP-0712402-B1 (EP)
Inventor: DONDIO GIULIO
IPC: A61K31/495
Filed: 1994-07-14
Granted: 2002-04-10
Abstract: PCT No. PCT/EP94/02325 Sec. 371 Date Apr. 18, 1996 Sec. 102(e) Date Apr. 18, 1996 PCT Filed Jul. 14, 1994 PCT Pub. No. WO95/04734 PCT Pub. Date Feb. 16, 1995Tricyclic derivatives of octahydroisoquinoline of formula (I), wherein n is zero or 1 and if n is zero, one of X or Y is NH, oxygen or sulphur, and the other is NH, CH or a R4- or R5-substituted carbon atom; if n is 1, then X and Y are both nitrogen, or one of them is nitrogen and the other is CH or an R4- or R5-substituted carbon atom, have selective receptor agonist or antagonist activity, and are of potential therapeutic utility as analgesics or immunomodulating and/or cardiovascular agents.   <IMAGE>
Patent EP-0694539-B1 (EP)
Inventor: WONG HENRY S
IPC: C07D305/14
Filed: 1995-07-27
Granted: 2001-11-28
Abstract: The present invention concerns taxane derivatives of formula I, <CHEM> wherein R<1> is hydrogen, C1-8 alkyloxy, C2-8 alkenyloxy, or C2-8 alkynyloxy, each can be optionally substituted with hydroxy; R is hydroxy, -OC(O)R<x> or -OC(O)OR<x>; R<4> and R<5> are independently C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, or -Z-R<6>; p is zero or one; Z is a direct bond, C1-8 alkylene or C2-8 alkenediyl; R<6> is aryl, substituted aryl, C3-8 cycloalkyl or heteroaryl; and R<x> is C1-8 alkyl optionally, substituted with one to six same or different halogen atoms, C3-8 cycloalkyl or C2-8 alkenyl; or R<x> is a radical of the formula <CHEM> wherein D is a bond or C1-8 alkyl; and R<a>, R<b> and R<c> are independently hydrogen, amino, C1-8 alkylamino, di-C1-8alkylamino, halogen, C1-8 alkyl, or C1-8 alkyloxy, their use as antitumor agents and pharmaceutical compositions containing the novel compounds.
Patent EP-0709611-B1 (EP)
Inventor: JESCHKE IMMANUEL
IPC: F16L13/14
Filed: 1995-08-23
Granted: 1998-05-20
Abstract: A corrugated section of the pipe (1) passes through the wall of the building. It is secured in the wall of the building so that it cannot be pulled free. The hose (2) comprises intersecting wires or strips (3) and it is fixed at the ends to those of the corrugated pipe. At the ends, both can be enclosed in a section of sealing pipe (4) to which they are welded. The corrugated and sealing pipes and the hose can all be of the same and pref. high-grade steel.
Patent EP-0709919-B1 (EP)
Inventor: HANNING WALTER
IPC: H01R9/26
Filed: 1995-09-06
Granted: 1998-11-04
Abstract: Distributor modules (1) are mounted side-by-side on a rail that has built-in power carrying tracks. A connecting distribution element (3) has a housing of insulation and embedded within this are metal pressings that are shaped to provide spring contact regions for externally inserted pins. Also built into the connection arrangement is a bridging element (12) that interconnects adjacent points and has a single contact with a base power rail. A number of such contact pairs can be built into a module.
Patent EP-0729532-B1 (EP)
Inventor: DEBLANDER JEAN-PHILIPPE JACQUE
IPC: B32B3/26
Filed: 1994-11-09
Granted: 2000-03-22
Abstract: The present invention refers to a multilayered insulating panel or element having (a) two outer facings (1), and (b) a soft synthetic foam core material (2) having hollow profiles (3), connected to both outer facings (1). Also disclosed is a multilayered insulating panel or element having (a) two outer facings (1), and (b) soft core material phases in a spaced relationship between the two outer facings in such a manner that both extremities of the soft core material are contacting the outer facings and having in between such soft core material phases, a second core material having a higher density than the soft core material, wherein only one extremity of each second core material phase contacts only one and the same outer facing. Both types of panel or element possess acoustic insulating properties and mechanical strength.
Patent EP-0758896-B1 (EP)
Inventor: PETSZULAT MONIKA
IPC: A61K31/52
Filed: 1995-02-24
Granted: 1998-08-19
Abstract: The invention relates to a topical preparation containing aciclovir. It has been found that the compound aciclovir, which is active against herpes simple, in an amphiphilc topical vehicle system is more stable and acceptable than the prior art O/W systems, while being having the same effectiveness against herpes labialis.
Patent EP-0758943-B1 (EP)
Inventor: SCHEDIN KURT
IPC: B27N3/08
Filed: 1995-04-03
Granted: 1999-07-28
Abstract: PCT No. PCT/SE95/00353 Sec. 371 Date Oct. 8, 1996 Sec. 102(e) Date Oct. 8, 1996 PCT Filed Apr. 3, 1995 PCT Pub. No. WO95/31318 PCT Pub. Date Nov. 23, 1995Apparatus for compressing mats of lignocellulose-containing material into board material is disclosed including a rotary compression roll having a perforated shell on its surface with axial ducts disposed within the rotary compression roll adjacent to that surface and a shoe adjacent to one end of the rotary compression roll in which the shoe includes a channel for injecting a processing medium into at least one of the axial ducts so that the processing medium is directed onto the mat in a processing section during compression of the mat by the rotary compression roll.
Patent EP-0788479-B1 (EP)
Inventor: HEISTRACHER ELISABETH
IPC: C07D209/48
Filed: 1995-10-17
Granted: 2000-04-19
Abstract: L'invention concerne des dérivés d'acide phtalimido-cinnamique substitués ont la formule (I), dans laquelle R1 = H, alkyle C¿1?-C4; R?2¿ = H, halogène, R3 = CN, NO¿2?, alkyle C1-C6, halogénure d'alkyle C1-C6, alcoxy C1-C6, halogénure d'alcoxy C1-C6; R?4¿ = H, CN, NO¿2?, Halogène, alkyle C1-C6; R?5¿ = H, alkyle C¿1?-C6, alkényle C2-C6, alkinyle C2-C6, alkyle substitué; R?6¿ = un des résidus figurant sous R5 ou CN, NO¿2?, alcoxy C1-C6, halogénure d'alcoxy C1-C6, alkylthio C1-C6, halogénure alkylthio C1-C6, cycloalkyle C3-C6, alkyle substitué, halogénure d'alkényle C3-C6, (alcoxy C1-C6)carbonyle, COOH, (alkylamino C1-C6)carbonyle, di-(alkyle C1-C6)aminocarbonyle, aminocarbonyle-(alkyle C1-C6)carbonyle, (halogénure d'alkényle C1-C6)carbonyle, aryle éventuellement substitué, hétaryle, aryle-alkyle C1-C6, ou hétaryle-alkyle C1-C6; ou R?5 et R6¿ désignent conjointement une chaîne alkylène, dans laquelle une unité méthylène peut être substituée par un groupe -O- ou par un groupe alkylimino; R7 = H, alkyle C¿1?-C6, alkényle C3-C6, alkinyle C3-C6, halogénure d'alkyle C2-C6, cyanoalkyle C1-C6, alcoxy C1-C6-alkyle C2-C6, alkylthio C1-C6-alkyle C2-C6 (alcoxy C1-C6)-carbonyle-alkyle C1-C6, cycloalkyle C3-C6, cycloalkyle C3-C6-alkyle C1-C6, phényle éventuellement substitué ou benzyle; X = O, S ou N (R?8¿), ainsi que les sels des dérivés de formule (I). Ces dérivés s'utilisent comme herbicides, ainsi que dasn la dessication/défoliation des végétaux.
Patent EP-0792233-B1 (EP)
Title: Portable apparatus for using bicycles as a type of watercraft
Inventor: SIVIERO ROBERTO
IPC: B63H21/175
Filed: 1995-11-07
Granted: 1999-04-28
Abstract: PCT No. PCT/IT95/00180 Sec. 371 Date Apr. 30, 1997 Sec. 102(e) Date Apr. 30, 1997 PCT Filed Nov. 7, 1995 PCT Pub. No. WO96/15026 PCT Pub. Date May 23, 1996A portable apparatus for using a bicycle not only on land but also as a type of watercraft has two oblong connected inflatable floats, a propulsion unit including a propeller and a clutch unit picking up a motion from a tire of a bicycle rearwheel, a rearjoint device for connection between rear parts of the floats and rear upper and lower forks of the bicycle, and a front joint device for connection a front of the floats with a lower bar of a bicycle frame, a quick-coupling clamp to which the clutch unit is fixed and which is securable to a bar of a saddle of the bicycle frame and connected to the propulsion unit by a flexible shaft so that by turning of pedals and therefore a rear wheel of the bicycle, movement is transferred through the flexible shaft to the propulsion unit, an element for connecting the two floats, a element for securing the bicycle, and the propulsion unit being formed so that the apparatus can be stowed inside shoulder packs and rucksacks for easy transport while riding the bicycle or carrying it by hand.