baber/WOPTO huggingface dataset:
Patent AU-2011219885-C1 (AU)
Title: Compounds as bradykinin B1 antagonists
Inventor: HAUEL NORBERT
IPC: C07D207/277
Filed: 2011-02-21
Granted: 2017-06-29
Abstract: The present invention provides the compounds of the general formula (I) in which n, R
Patent AU-2014249022-C1 (AU)
Title: Systems and methods for detection of cells using engineered transduction particles
Inventor: REY DIEGO ARIEL
IPC: C12P19/34
Filed: 2014-03-11
Granted: 2019-02-07
Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.
Patent AU-2014350608-C1 (AU)
Title: Screening device
Inventor: BIRNBAUM HORST
IPC: B07B1/48
Filed: 2014-11-10
Granted: 2018-01-18
Abstract: Disclosed is a screening device comprising elastic screen lining elements that are attached to first (3) and second cross-bars (4), the first (3) and second cross-bars (4) being alternately arranged in a vibrationally driven frame (1) of the screening device. The first cross-bars (3) are rigidly connected to the frame (1), and the second cross-bars (4) are mounted in the frame (1) by means of spring elements (5). According to the invention, the frame (1) has openings (6) for accommodating the spring elements (5), said openings (6) being located in the region of the end faces of the second cross-bars (4).
Patent AU-2018200503-C1 (AU)
Title: Compositions and methods for the depletion of cd117+ cells
Inventor: NIXON ANDREW
IPC: C07K16/28
Filed: 2018-01-22
Granted: 2020-08-27
Abstract: COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD117+ CELLS 
Abstract of the Invention 
The invention provides compositions and methods useful for the depletion of 
5 CD117+ cells and for the treatment of various hematopoietic diseases, metabolic 
disorders, cancers, and autoimmune diseases, among others. Described herein are 
antibodies, antigen-binding fragments, ligands, and conjugates thereof that can be 
applied to effect the treatment of these conditions, for instance, by depleting a population 
of CD117+ cells in a patient, such as a human. The compositions and methods 
10 described herein can be used to treat a disorder directly, for instance, by depleting a 
population of CD117+ cancer cells or autoimmune cells. The compositions and methods 
described herein can also be used to prepare a patient for hematopoietic stem cell 
transplant therapy and to improve the engraftment of hematopoietic stem cell transplants 
by selectively depleting endogenous hematopoietic stem cells prior to the transplant 
15 procedure.
Patent RU-2158078-C1 (RU)
Inventor: KUZHELEV A V
IPC: A01K1/015
Filed: 2000-02-08
Granted: 2000-10-27
Abstract: Изобретение относится к средствам гигиены и предназначено для адсорбции жидких и твердых отходов животного и поглощения вредных газов от этих отходов и представляет собой гранулированный газобетон, характеризующийся следующими параметрами: насыпной плотностью 400 - 650 кг/м 3 ; адсорбционной емкостью влагопоглощения 75 - 95%; гранулометрическим составом от 0,6 до 10,0 мм; сорбционной емкостью по аммиаку 0,7 - 0,9 мг - экв/г; рН 7,0, дающими возможность только в указанном интервале количественных значений получить качественный наполнитель туалета для домашних животных, адсорбирующий жидкие и твердые отходы животного и соответствующий санитарным нормам поглощения запаха, например, аммиака от этих отходов. 1 з.п. ф-лы.
Patent RU-2177659-C1 (RU)
Title: Electron-beam gun
Inventor: CHUKLINOV S V
IPC: B23K15/00
Filed: 2000-06-15
Granted: 2001-12-27
Abstract: FIELD: welding equipment. SUBSTANCE: electron-beam gun has anode 2, cathode 3, trap 4, focusing lens 5, deflecting yoke 6, gate electrode 7, and case 8 all arranged along its optical axis 1. Trap 4 mounted in anode 2 and made in the form of bush of getter material absorbing active gases and ions heats up during gun operation. EFFECT: simplified design and enhanced reliability of gun. 4 cl, 1 dwg
Patent RU-2184257-C1 (RU)
Title: Automobile with gas turbine engine
Inventor: GRIGORCHUK V S
IPC: F02C6/20
Filed: 2000-11-14
Granted: 2002-06-27
Abstract: FIELD: automotive industry. SUBSTANCE: automobile with gas turbine engine has starting electric motor with centrifugal clutch, step-down reduction gear and gas turbines mounted on common shaft in separate housing closed by covers. One end of shaft is coupled with centrifugal clutch and the other is connected with driving shaft of step-down reduction gear. Intake and outlet channels of each gas turbine are interconnected by pipeline provided with cooler and union with shutoff cock mounted from outside and connected with compressed hydrogen cylinder and accommodating gas ionizer, accelerating system and converter. Inner spaces of gas turbines and pipelines are filled with hydrogen under pressure which serves as working medium. Gas ionizers, accelerating systems and converter of gas turbines are electrically connected with nuclear (isotopic) high-voltage batteries through switching device mechanically connected with accelerator pedal. EFFECT: improved fire safety of automobile, reduced discharge of harmful substances into atmosphere, no time wasting for filling. 11 dwg
Patent RU-2185386-C1 (RU)
Title: Method for sulfoethylation of ligno-carbohydrate materials
Inventor: GALOCHKIN A I
IPC: C08B11/10
Filed: 2000-12-13
Granted: 2002-07-20
Abstract: FIELD: resin industry and chemical engineering. SUBSTANCE: invention aims at production of sodium salts of sulfoethyl esters of ligno-carbohydrate materials, which can be used as chemical additives for controlling properties of washing fluids when boring oil and gas holes, for stabilizing cement mortars in building industry, and as reagents in ore flotation. Method consists in that preliminarily activated cellulose-based material, in particular unseparated cellulose/lignin/hemicellulose mixture, is affected by sodium beta- chloroethylsulfonate in boiling isopropyl alcohol for 3 h, observing fluid modulus 1:20. EFFECT: utilized total amount of ligno-carbohydrate material, reduced cost of final product, and enabled wasteless technology. 1 tbl
Patent RU-2186782-C1 (RU)
Title: Inclusion complexes of derivatives of 1,2,5-oxa- -diazole-2-oxide with polycyclic derivatives of glucopyranose, method of their synthesis, pharmaceutical composition
Inventor: KHROPOV JU V
IPC: C07D271/08
Filed: 2001-01-16
Granted: 2002-08-10
Abstract: FIELD: organic chemistry, biochemistry, pharmacy. SUBSTANCE: invention relates to novel inclusion complexes of derivatives of 1,2,5-oxadiazole-2-oxide of the general formula (I)   where R 1  = R 2  is CN or in common with adjacent carbon atoms form annelated 3,6-bis-(lower alkyl)-pyridazine-1,2-dioxide cycle with polycyclic derivatives of glucopyranose of the general formula (II)   where if n = 1 then R 3  means a fragment of 11-oxo-18β, 20β-olean-12-ene-29-oic acid of the formula (III)   R 4  is H; R 5  is β-D-glucopyranosyl; R 6  = R 7  is H; R 8  means C(O)OH; and if n = 7 then R 3  is H; R 4  and R 7  are direct bonds; R 5  and R 6  mean H or (CH 2 CH(CH 3 )O) m H where m = 1-14; R 8  means -CH 2 OH or CH 2 O(CH 2 CH(CH 3 )O) m H where m = 1-14. New compounds produce nitrogen oxide and activate the soluble form of guanylate cyclase and relate to spasmolytic, vasodilating and hypotensive agents of rapid effect and they are inhibitors of platelet aggregation. Invention relates to a method of their synthesis and pharmaceutical compositions based on thereof. The proposed compounds are synthesized by the method involving interaction of the parent derivative of 1,2,5-oxadiazole-2-oxide of the above given formula (I) where   and R 2  have the indicated values with the corresponding polycyclic derivative of glucopyranose of the above given general formula (II) where R 3 -R 8  have the indicated values. Synthesis is carried out in an aqueous-organic medium (for example, in an aqueous solution of dioxane, lower alkanol, in part ethanol, or a mixture of organic solvents) at increased temperature 30-60 C followed by isolation of the end product by evaporation under decreased pressure, its washing out with low-polar inert organic solvent (diethyl ether or its mixture with hexane) and drying under decreased pressure. Novel inclusion complexes are effective donors of NO and produce its redox-form (nitroxyl) also, form nitrosothiols and activate guanylate cyclase soluble form and show also spasmolytic, vasodialting and rapid hypotensive effect. The described compounds show the expressed anti-aggregative properties also. EFFECT: valuable medicinal properties. 16 cl, 4 dwg, 6 tbl
Patent RU-2183024-C1 (RU)
Inventor: KUZNETSOV S JU
IPC: G01T1/169
Filed: 2001-02-13
Granted: 2002-05-27
Abstract: Использование: для контроля радиационной обстановки окружающей среды. Сущность: активная система радиационного мониторинга включает блок обработки данных, стационарные дозиметрические приборы, индивидуальные дозиметрические приборы, поисковые дозиметрические приборы, передатчики дозиметрических приборов, а также контрольно-исполнительные посты, состоящие каждый из генератора электромагнитного излучения, электромагнитно-волнового приемника, передатчика сигналов и блокирующего узла. Технический результат: расширение области применения и повышение достоверности работы. 1 ил.
Patent RU-2184645-C1 (RU)
Inventor: KHUDOBIN L V
IPC: B24D5/00
Filed: 2001-02-27
Granted: 2002-07-10
Abstract: FIELD: metal working, possibly grinding of blanks with regular pointed-apex profile, for example grinding threads. SUBSTANCE: grinding disc has intermittent working surface with regular profile, for example with thread profile. Working surface of grinding disc includes even number of portions profiled with pitch 2P, where P - profile pitch of ground blank. Profiles of portions of working surface are shifted one relative to another by value P. Every other thread of blank is ground and each protrusion of thread profile is worked at one side. Next working portion works other side of thread profile. EFFECT: enhanced quality and efficiency of thread grinding due to lowered (more than twice) thermal stresses at working. 3 dwg
Patent RU-2194459-C1 (RU)
Inventor: KRYLOV V V
IPC: A61B17/00
Filed: 2001-03-28
Granted: 2002-12-20
Abstract: FIELD: medicine, neurosurgery. SUBSTANCE: one should resect the external leaf of dura mater (DM) 2-3 cm above and below craniovertebral transition (atlanto-occipital membrane), meningeolysis is carried out 0.8-1.2 cm for both sides against the incision to tighten up an internal wall of dural sac in dorsolateral directions with the help of handles by external lateral leaves. In area of craniovertebral transition DM is fixed from ventral side to an atlas body and cranial slope. Handles are sutured to periosteum of occipital bone scale. To prevent further lowering of cerebellar hemispheres into osseous defect it is necessary not to continue DM resection upwards above cerebellar hemispheres by limiting it with area of occipital-cervical transition only. The method enables to remove the compression of brain trunk, restore a large occipital cistern and improve cliniconeurological picture of the disease in patients with Chiari's anomaly of type I. EFFECT: higher efficiency. 1 ex, 2 tbl
Patent RU-2183845-C1 (RU)
Title: Method of geochemical search for deposits of mineral resources
Inventor: VOSTROKNUTOV G A
IPC: G01V9/00
Filed: 2001-03-30
Granted: 2002-06-20
Abstract: FIELD: search for mineral products. SUBSTANCE: invention is meant for processing of materials of small-scale geochemical searches, for prediction of latent and buried mineralization, for conducting searches under unfavorable landscape conditions, for exposure of low-contrast objects. Method of geochemical search for deposits of mineral resources is related to geology and includes sampling of natural objects where presence of geochemical haloes is presumed. Multielement analysis of samples for ore-forming and accompanying chemical elements- indicators is conducted. Obtained multidimensional geochemical data are standardized by division of contents of elements into percentage abundance ( background )values or they are converted into standardized, numbered and other values having close functions and parameters of distribution. Standardized values are arranged in each sample in the order of their decrease. Arranged geochemical spectra are compared with use of nonparametric Spearman criterion (Rsp). Ore-halo classes of samples are exposed and their similarities with specified standard classes of ores or periore halos is determined. EFFECT: possibility of detection of content of chemical elements in deposits of weakly exposed mineral resources. 1 cl _
Patent RU-2190644-C1 (RU)
Title: Композиция для получения криогеля поливинилового спирта и способ получения криогеля
Inventor: LOZINSKIJ V I
IPC: C08L29/04
Filed: 2001-04-26
Granted: 2002-10-10
Abstract: Изобретение относится к композитным полимерным гелям и процессам их получения и касается криогелей на основе поливинилового спирта (ПВС). Заявляемые материалы могут быть использованы в биотехнологии в качестве хроматографических или адсорбционных матриц, а также в биомедицинской практике, например в качестве гемосорбентов. Задачей изобретения является получение композитных криогелей ПВС однородной структуры с улучшенными физико-механическими свойствами и расширение круга гидрофобных наполнителей, которые можно ввести в состав композитных криогелей ПВС. Указанная задача решается тем, что состав исходной композиции для получения целевого продукта по заявляемому решению включает от 6 до 26 мас.% ПВС, от 3 до 33 мас.% гидрофобного наполнителя и от 55 до 90 мас.% растворителя - диметилсульфоксида (ДМСО), при этом наполнитель вносится в ДМСО-раствор ПВС в сухом виде. Далее приготовленную суспензию замораживают при 15...-30 o С, выдерживают в замороженном состоянии 1-24 ч и оттаивают, после чего полученный композитный криогель промывают водой для замены ДМСО на водную среду. 2 с.п. ф-лы, 1 табл.
Patent RU-2204768-C1 (RU)
Title: Running water heater on gas cooker
Inventor: ZEMLJAKOV N V
IPC: F24H1/00
Filed: 2001-10-01
Granted: 2003-05-20
Abstract: FIELD: domestic appliances for heating running water on gas cooker. SUBSTANCE: portable water heater operating on two burners of gas cooker has heat accumulating casing accommodating water heating element made of metal tube with its both ends provided with two flexible hoses, one for cold water admission and other, for hot water outlet, inner surface of casing being covered with multilayer heat-resistant heat insulation which is coated with protective material; water heating element is made in the form of a few zigzag-shaped or concentric tubular coils disposed in tandem in several tiers, one on top of other, within casing that has control valve in its top part; planar coils of bottom tier are locally disposed above cooker burners and tilted to cooker through angle α which may be from 3 to 15 deg; in addition admission hose is joined on one end through flexible sleeve to kitchen-sink mixer nozzle and outlet hose is provided with separate nozzle that has clamp for joining to kitchen-sink mixer nozzle. In addition water heating element may be made of thin-walled copper, brass, stainless-steel, or aluminum tubes; each coil of bottom tier is made of parallel straight tubes spaced 1-5 mm apart and their ends are joined together with aid of rectilinear or semicircular tie plates to form tubular series circuit. EFFECT: enhanced safety, reduced space requirement of water heater. 9 cl, 9 dwg
Patent RU-2203861-C1 (RU)
Title: Method of activation of water
Inventor: PYNDAK V I
IPC: C02F1/46
Filed: 2001-11-12
Granted: 2003-05-10
Abstract: FIELD: electrochemical treatment of water and aqueous solutions. SUBSTANCE: method includes treatment of water by electric current in electric field formed by flat electrodes in anode and cathode zones of electrolyzer separated by diaphragm. Electrodes with through holes are used in activation, electrodes are mounted in electrolyzer for discrete change of distance between them. Solution of mineral fertilizers are added into starting water. EFFECT: reduced power input into technological process of activation, enhanced efficiency of activated water in plant growing. 2 cl, 4 dwg
Patent RU-2204641-C1 (RU)
Title: Guide track for vehicle
Inventor: GNEZDILOV V A
IPC: E01B25/00
Filed: 2001-12-13
Granted: 2003-05-20
Abstract: FIELD: transport engineering. SUBSTANCE: invention relates to transportation system of different application. Proposed guide track contains two support members 1, at least one longitudinal member 2 with convexity between supports pointed upwards, and cross members 3 and 4 bracing said members. Side sheets 5 connecting members 1 and 2 are used for standardization. EFFECT: increased rigidity of construction. 6 cl, 4 dwg
Patent RU-2218318-C1 (RU)
Title: Explosive compound
Inventor: KANTOR V KH
IPC: C06B31/28
Filed: 2002-04-04
Granted: 2003-12-10
Abstract: FIELD: explosive compounds used as deep-hole and blast-hole charges in the mining industry. SUBSTANCE: the explosive compound contains granular ammonium nitrate with a volume of pores within 0.07 to 0.18 cu.cm/g, liquid petroleum product and powder of aluminum or aluminum alloy or silicon alloy, or a mixture of two any mentioned powder in relationship 4:1-1:1.5. The explosive compound may additionally may additionally contain 2.0 to 5.0 mass percentage of water or aqueous solution of passivating additive above 100%. EFFECT: enhanced efficiency, which makes it possible to use in blasting operations as deep-hole and blast-hole explosives for breaking of rocks of any hardness at a temperature within +50 to -40C. 7 cl, 1 tbl
Patent RU-2198709-C1 (RU)
Title: Cyclist exercising apparatus
Inventor: AFANAS EV JU V
IPC: A63B69/16
Filed: 2002-04-29
Granted: 2003-02-20
Abstract: FIELD: sportive equipment. SUBSTANCE: cyclist exercising apparatus has cycle mounting frame with rolls, support for carrying frame, which is positioned for rocking in longitudinal plane, follower made in the form of conical eccentric, roller mounted on frame for contacting with follower and displacement along its axis, round guide fixed on frame, carriages located on round guide, and at least two ventilation devices positioned on carriages and adapted for directing air flow to cyclist. One part of ventilation devices is positioned on carriage at side opposite to drive roll and other part is positioned on carriage for moving along frame perimeter. EFFECT: increased efficiency in exercising by simulating conditions approximating that of natural track. 3 cl, 2 dwg
Patent RU-2212633-C1 (RU)
Title: Hydraulic system of electro-droplet-jet printer and its components
Inventor: BEZRUKOV V I
IPC: B41J2/04
Filed: 2002-05-27
Granted: 2003-09-20
Abstract: FIELD: electro-droplet-jet technology and printers using this technology. SUBSTANCE: hydraulic system has ink tank communicating with solvent delivery, suction, pressure-relief, viscosity metering, and metered make-up circuits; it also has evacuation circuit and nozzle air- or solvent-cleaning circuit, and also solvent-washing circuit for droplet producer and nozzle. Delivery circuit has series-connected intake pipe with first submersible filter of ink tank, delivery pump, check valve, working receiver, second filter, and droplet producer with valve and nozzle member. Suction circuit has series-connected unused droplet trap, entrapped jet sensor of trombo-optic type, filter, suction pump, drain pipe, and ink tank. Viscosity metering circuit includes delivery-circuit pump and also has metering receiver, pressure sensor, and then capillary duct and viscosity metering pipe of ink tank all connected to pump upstream of working receiver check valve. Solvent make-up circuit includes solvent tank, submersible filter at intake pipe edge communicating with make-up pump and terminates in drain pipe in ink tank. Pressure-relief and ink pumping circuit provides communication between droplet producer and ink tank through its valve and pressure-relief valve. Washing circuit has make-up valve at make-up pump inlet and tee-piece upstream of this valve with tap to droplet producer through washing valve installed in circuit. Pressure-relief and ink-pumping circuit is integrated with evacuation circuit and with nozzle cleaning circuit. Pressure-relief circuit provides communication between droplet producer and suction pump inlet through pressure- relief valve and enables insertion of evacuation valve in delivery circuit upstream of droplet producer valve. Trap valve is included in suction circuit at inlet of suction pump. Proposed hydraulic system provides for automatic cleaning of nozzle and system structure, as well as system preservation thereby enhancing its consumer demands. EFFECT: facilitated manufacture, enhanced effectiveness and reliability of system components; enhanced reliability and quality of printing. 33 cl, 21 dwg, 2 tbl
Patent RU-2225722-C1 (RU)
Title: Method for preparing human interferon
Inventor: ANTIPOVA T O
IPC: A61K38/21
Filed: 2002-07-11
Granted: 2004-03-20
Abstract: FIELD: biotechnology. SUBSTANCE: invention relates to methods for preparing and purification of genetic-engineering preparations of human interferon. Method involves culturing cells of microorganism Pseudomonas putida, cells lysis with their simultaneous disruption, treatment of cells with polyethyleneimine, separation of nucleic acids, proteins desalting with ammonium sulfate, three-stage chromatography on cation-exchange hydrophobic sorbent Solosa KG, anion-exchange resin Spherocell-QAE and hydrophobic sorbent Spherocell LP-M followed by concentrating by methods of ultrafiltration and gel-filtration on Sephadex G-100. The proposed purification schedule provides enhancing the yield of interferon up to 30%. EFFECT: improved preparing method, enhanced yield of interferon. 1 ex
Patent RU-2230276-C1 (RU)
Title: Device for throwing of net and method for net packing in the device
Inventor: KORSUKOV V S
IPC: F41B15/10
Filed: 2002-10-07
Granted: 2004-06-10
Abstract: FIELD: nonlethal weapon, in particular, weapon for catching of living beings by means of net throwing. SUBSTANCE: the device has a launcher, tapered bell with barrels, nets packed in the inner cavity of the bell closed with a cover, and loads fastened in the periphery of the nets and laid in the barrels of the bell. The bell barrels have a variable diameter, the barrels with a larger diameter equal to the diameter of the loads are closer to the outlet cut of the barrels. The loads are cylinder-shaped, they are fastened on the net with the aid of elastic cords, they are placed in the barrels with orientation of the points of attachment to the cut of the barrels and have triangle-shaped grooves with the point oriented to the high-pressure chamber. The bell barrels are installed in the longitudinal axis at a definite angle. The essence of the packing consists in the fact that the net is suspended from the marked center, the loads are alternately attached with the aid of tinted cords in the periphery of the nets and packed up in the same sequence one after another in the bell barrels. Having pushed through the hand between two cords and seized the center of the net from inside, the net is drawn out between these cords and turned inside out. In the spaces between these cords, beginning from the center, the net is packed up in the bell cavity and the bell cavity with the net is closed with the cover. EFFECT: enhanced efficiency of the weapon and simplified process of net packing in the device. 2 cl, 4 dwg