baber/WOPTO huggingface dataset:
Patent FI-952867-A0 (FI)
Inventor: KARJALAINEN ARTO JOHANNES
IPC: A61K31/4164
Filed: 1995-06-09
Abstract: PCT No. PCT/FI93/00539 Sec. 371 Date May 19, 1995 Sec. 102(e) Date May 19, 1995 PCT Filed Dec. 14, 1993 PCT Pub. No. WO94/13645 PCT Pub. Date Jun. 23, 1994New compounds of formula (I) wherein R1 is H, CH3, OCH3, NO2, NH2, CN, CF3, CHF2, CH2F or halogen, R2 is a heterocyclyl radical selected from 1-imidazolyl, triazolyl, tetrazolyl, pyrazolyl, pyrimidinyl, oxazolyl, thiazolyl, isoxazolyl and isothiazolyl, R3 is H or OH, R4 is H, R5 is H or OH; or R4 is H and R3 and R5 combined form a bond; or R3 is H and R4 and R5 combined form -(O); R6 is methylene, ethylene, -CHOH-, -CH2-CHOH-, -CHOH-CH2-, -CH-CH- or -C(-O)-; or R4 is H and R5 and R6 combined is -CH- or -CH-CH2-; stereoisomers thereof and non-toxic pharmaceutically acceptable acid addition salts thereof exhibit selective aromatase inhibiting properties, compared with their desmolase inhibiting properties. The compounds of the invention are valuable in the treatment of estrogen dependent diseases, e.g. breast cancer or benign prostatic hyperplasia (BPH).
Patent FI-954106-A0 (FI)
Inventor: DUPUY PIERRE
IPC: H04W24/00
Filed: 1995-09-01
Abstract: The method involves calculating the difference (RTD=R12-0, R12-1) between a first time reference of a first oscillator and a second time reference of a second oscillator at two successive instants (t0,t4). This is determined as a function of the propagation time difference associated with the first and second oscillators. The variation between the calculated reference time differences is determined by a time unit. The frequency difference between the oscillators is determined in response to a variation in the calculated time differences which is greater than a given threshold.
Patent FI-954681-A0 (FI)
Inventor: MUELLER ULRICH
IPC: C07D471/04
Filed: 1995-10-02
Abstract: Cycloalkano-indole derivs. and aza analogues of formula (I) and isomers and salts are new. R1-C=C-R2 = phenyl, pyridyl or a gp. of formula (a), all opt. substd. by 1-3 gps. R'; R8 = H or 1-4C alkyl; R3-C=C-R4 = phenyl, 4-8C cycloalkene or 4-8 membered oxocycloalkane (all opt. substd. by 1-3 gps. R'); R' = independently halo, CF3, COOH, OH, up to 6C alkoxy carbonyl, 1-6C alkoxy, or 1-6C alkyl (opt. substd. by OH or 1-4C alkoxy); R = H, 4-12C cycloalkyl or 1-12C alkyl; A = CO or CS; X = O, S or NR9; R9 = H or 1-6C alkyl (opt. substd. by OH or phenyl); R5 = phenyl or 5-8 membered, opt. unsatd. heterocyclic with 1-3 heteroatoms (S, N and/or O), (both opt. mono- to tri-substd. by NO2, COOH, halo, CN, 2-6C alkenyl, 1-6C alkoxy or alkyl (opt. substd. by OH, COOH, 1-6C alkoxy or up to 6C alkoxycarbonyl; and/or opt. mono- substd. by OR10 or NR11R12); R10 = H, 1-6C alkyl or 2-6C alkenyl; R11, R12 = H, phenyl, 1-6C alkyl, or up to 8C acyl (opt. subst. by NR13R14); R13, R14 = H or up to 8C acyl; R7 = H; R6 = H, COOH, 1-5 alkoxy, or 1-6C alkyl (opt. substd. by OH or OCOR15); or R6+R7 = O; R<15> = phenyl (opt. mono- to tri-substd., by halo, OH or 1-5C alkyl), or 1-22C alkyl or 2-22C alkenyl (both opt. substd. by OR16); R16 = H, benzyl, triphenylmethyl or up to 6C acyl. Also claimed are intermediates of formula (II).
Patent IL-60204-A0 (IL)
Title: 2-aminopropanal-acetals,their preparation and their use as fungicides
IPC: C07D261/18
Filed: 1980-05-06
Abstract: 1. Claims for the Contracting States : BE, CH, LI, DE, FR, GB, IT, LU, NL, SE A 2-(N-aryl-n-acyl)-aminopropanal-acetal of the general formula I  see diagramm : EP0019745,P23,F3  where X**1 , X**2 and X**3 independently of one another are oxygen or sulfur, Y is oxygen, sulfur or NR**7 , n is 0 or 1, R**1 is C1 -C4 -alkyl, R**2 is hydrogen, halogen, C1 -CV4 -alkyl or C1 -C4 -alkoxy, R**3 is hydrogen, halogen or C1 -C4 -alkyl, R**4 and R**5 independently of one another are unsubstituted or substituted alkyl or arylalkyl or together are alkylene and form part of a 5-membered or 6-membered heterocyclic ring which may or may not be substituted by alkyl or aryl, R**6 is unsubstituted or substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl or heteroaryl, with the exception of chloromethyl and acetylmethyl, and if n is 1, R**6 may also be unsubstituted or substituted alkynyl, aryl, arylalkyl or heteroarylalkyl, and R**7 is hydrogen, alkyl or alkoxy. 1. Claims for the Contracting State : AT A fungicide containing a 2-(N-aryl-n-acyl)-aminopropanalacetal of the formula  see diagramm : EP0019745,P27,F1  where X**1 , X**2 , and X**2 independently of one another are oxygen or sulfur, Y is oxygen, sulfur or NR**7 , n is 0 or 1, R**1 is C1 -C4 -alkyl, R**2 is hydrogen, halogen, C1 -C4 -alkyl or C1 -C4 -alkoxy, R**3 is hydrogen, halogen or C1 -C4 -alkyl, R**4 and R**5 independently of one another are unsubstituted or substituted alkyl or arylalkyl or together are alkylene and form part of a 5-membered or 6-membered heterocyclic ring which may or may not be substituted by alkyl or aryl, R**6 is unsubstituted or substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl or heteroaryl, with the exception of chloromethyl and acetylmethyl, and if n is 1, R**6 may also be unsubstituted or substituted alkynyl, aryl, arylalkyl or heteroarylalkyl, and R**7 is hydrogen, alkyl or alkoxy.
Patent IL-66282-A0 (IL)
Title: Pharmaceutical compositions of xanthine derivatives tolerated by the stomach and process for their preparation
IPC: A61K9/00
Filed: 1982-07-09
Abstract: A pharmaceutical composition of xanthine derivatives being well tolerated by the stomach and containing a mixture of granules coated with a gastric juice-resistant material and of a portion of up to 30% of granules soluble or partially soluble in gastric juice and process for its preparation.
Patent IL-75210-A0 (IL)
Title: Yeast vector
IPC: C12N15/90
Filed: 1985-05-15
Abstract: A DNA sequence comprises a gene that codes for resistance to antibiotic G418 functionally coupled to a yeast promoter sequence or to a synthetic promoter sequence. The DNA sequence may be directly selected for in a yeast cell transformed with the DNA. Vectors containing the DNA sequence and a gene encoding the desired heterologous protein can be used to transform yeast cells so that those cells or their descendants may be used to harvest the desired protein. <IMAGE>
Patent IL-80755-A0 (IL)
Title: Eukaryotic fusion proteins,the preparation and use thereof,and means for carrying out the process
IPC: C12N15/62
Filed: 1986-11-25
Abstract: Fusion proteins in which the C- or N-terminal essentially corresponds to the first 100 units of interleukin 2 are new. Also new are gene structures coding for the above fusion proteins, vectors containing these gene structures, and hot cells containing these vectors. Hirudin derivs. with an amino acide sequence begining N-terminally with Pro are new and claimed. Human interleukin 2 derivs. contg. Asp. C-terminally are new and claimed.
Patent IL-83506-A0 (IL)
Title: Meta-halo-phenolic alkylation products and epoxy systems
IPC: C08F8/20
Filed: 1987-08-12
Abstract: The invention concerns a coupled aromatic compound represented by the formula  Ar - Y      I wherein Ar is an aromatic moiety different from Y and Y is an aromatic moiety represented by one of the formulae: <CHEM>  wherein A is an aliphatic ring system bonded to the aromatic ring; Q is separately at each occurrence hydrogen, alkyl or inertly substituted alkyl with proviso that the carbon atom bonded to the aromatic ring is a primary or secondary carbon atom,  X is separately at each occurrence a halogen moiety, Z is a nitrogen- or chalcogen-containing moiety, and their preparation. The materials contain a moiety such as, for example, 4-oxy-3,5-dimethyl-2,6-dibromobenzyl which can impart a high degree of thermal and hydrolytic stability to the materials, for example, epoxy thermosets such as in electronic encapsulations. For example, when used in electronic encapsulation formulations, these materials can provide a substantial increase in electronic device reliability. Their preparation involves an alkylation of an aromatic ring, for example, such as a Friedel-Crafts alkylation with 4-bromomethyl-3,5-dibromo-2,6-dimethylphenol or with 4-hydroxymethyl-3,5-dibromo-2,6-dimethylphenol.
Patent IL-88405-A0 (IL)
Title: Cream substitute ingredient and frozen dessert food products containing it
IPC: A23G9/32
Filed: 1988-11-17
Abstract: New frozen whipped dessert foodstuffs have fat and/or oil partially or totally replaced by a macrocolliod. The macrocolloid comprises non-aggregated particles of denatured protein of mean dia. in the dry state of 0.1-2.0 microns. Less than 2% of the particles exceed 3.0 microns dia. and the particles are mainly spheroidal (800x optical microscopy). - Pref. the macrocolloid replaces dairy fat. It replaces over 50% (100% of the fat and/or oil). The foodstuff is an analog of ice cream contg. under 1% fat. The protein is denatured dairy whey protein, egg albumen, soy or bovine serum albumin. The foodstuff has at least 1x10 power 8 (9-12) particles per cc having dia. 0.5-2.5 microns. It contains less than 1% fat. The desserts are pred. from a premix of 5-20% protein, (25-100% of which is heat coagulable), by heat pasteurisation and high shear conditions. Cream substitute, sauces icing, cream pie fillings, spread and dips are new.
Patent IL-89781-A0 (IL)
Title: Laser system
IPC: H01S3/03
Filed: 1989-03-28
Abstract: The invention relates to improved optical resonators, of enhanced stability. These are of special value in laser systems. The novel system is characterized by a stable operation and high performance, the configuration of the system being a rather compact one. The stable resonators of the invention have an annular configuration of the lasing medium (5) and comprise as intercavity element a waxicon or axicon (18).
Patent IL-94548-A0 (IL)
Title: Phenylacetic acid derivative,process for the preparation thereof and a pharmaceutical composition containing the same
IPC: A61K31/195
Filed: 1990-05-29
Abstract: This invention relates to a zinc derivative of phenylacetic acid, a process for preparing this compound by reacting 2-(2,6-dichloroaniline) phenylacetic acid with zinc oxide, hydroxides, carbonates or salts, or a corresponding salt of the said acid is reacted with a zinc salt. The reaction takes place in a polar solvent. The new compound has antiulcer activity.
Patent AU-PP515198-A0 (AU)
Title: Casting steel strip
IPC: C23C18/31
Filed: 1998-08-07
Abstract: In twin roll casting of steel strip, molten steel is introduced into the nip between parallel casting rolls (16) to create casting pool (30) supported on casting surfaces (16A) of the rolls and the rolls are rotated to deliver solidified strip (20) downwardly from the nip. Casting surfaces (16A) are textured by a random pattern of discrete projections having pointed peaks with a surface distribution of between 10 and 100 peaks per mm<2> and an average height of at least 10 microns. The random texture may be produced by grit blasting the casting surfaces on a substrate covered by a protective coating. Alternatively the texture may be produced by chemical deposition or electrodeposition of a coating onto a substrate to form the casting surfaces.
Patent AU-PQ307799-A0 (AU)
Title: Improvements relating to cooling of dies
IPC: B29C/
Filed: 1999-09-24
Abstract: An arrangement to assist in heat transfer through a mold for applications such as injection molding of plastics material including at least one closed chamber within the mold, the chamber being only partially filled with liquid and a remainder of the chamber being filled with substantially only vapor of the liquid within the chamber, at least a portion of the chamber being positioned to transmit heat from a targeted location of the mold into liquid within the chamber, and condensing means adapted by reason of heat exchange to effect condensation of vapor within the chamber, the mold being arranged in that the liquid such as water is arranged to be held in the chamber in such a way that the liquid will be distributed to reach or be held at different heights within the chamber. This is achieved in one case by the addition of a foaming agent in the liquid. In another case by having a flock attached to the inner surface of the chamber. In a further example there are separate tiers of reservoirs holding the liquid above a base level of the liquid.
Patent FI-20011658-A0 (FI)
IPC: B03D1/14
Filed: 2001-08-17
Abstract: The invention relates to a flotation machine used for separating valuable ingredients, such as metal concentrates, from the rest of the material, which flotation machine comprises at least means for feeding slurry to be treated in the flotation cell into said flotation cell, means for agitating the slurry by a rotor which is to be rotated by a rotation device installed in the vertical direction of the flotation cell underneath the rotor, means for feeding air into the slurry, means for removing the material flotated in the flotation cell and means for removing material that is left non-flotated in the flotation cell. According to the invention the shaft (11, 28) of the rotor (10, 26) meant for agitating the slurry (3, 23) and for feeding air into the slurry (3, 23) and of the rotation device (12, 27) is sealed in the flotation cell (1, 21) by a mechanical sealing member (15).
Patent FI-20020774-A0 (FI)
Inventor: BORG ALE
IPC: H04L1/22
Filed: 2002-04-22
Abstract: A method and a system for ensuring the operation of a field bus. In the method the field bus is controlled with two control servers one of which is at a time set active and one is set passive. The control servers are connected with a backup bus. In the method, a first message is sent at intervals from the active control server via said field bus to the passive control server, and the active control server waits for a response message to the first message from the passive control server. If the active control server does not receive said response message within a predetermined time, first data on the fault situation is set. The passive control server waits for said second message, in which case if the passive control server does not receive said first message within a predetermined time, second data on the fault situation is set. The invention also relates to a system, in which the method is applied, as well as to a control server to be used in the system.
Patent IL-101129-A0 (IL)
Title: Biotechnological process for the preparation of s-(+)-2,2-dimethylcyclopropanecarboxamide
IPC: C12R1/07
Filed: 1992-03-03
Abstract: A microbiological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide, starting from R,S-(+/-)-2,2-dimethylcyclopropanecarboxamide. For this process, new microorganisms are selected and isolated, which are capable of biotransforming R-(-)-2,2-dimethylcyclopropanecarboxamide in racemic 2,2-dimethylcyclopropanecarboxamide to R-(-)-2,2- dimethylcyclopropanecarboxylic acid. The process can then be performed either with the microorganisms or with the cell-free enzymes from the microorganisms.
Patent IL-104487-A0 (IL)
Title: Laminated films
IPC: B32B27/32
Filed: 1993-01-22
Abstract: PCT No. PCT/GB93/00177 Sec. 371 Date Jun. 16, 1994 Sec. 102(e) Date Jun. 16, 1994 PCT Filed Jan. 28, 1993 PCT Pub. No. WO93/14928 PCT Pub. Date Aug. 5, 1993A cross-laminate of two or more individually stretch oriented films where the directions of orientation of the films are in criss-crossing relation, has a pattern of generally parallel elongated ribs extending lengthwise of the laminate. The ribs are defined between generally transversely coincident convex and concave curved surfaces on opposite faces of the laminate, the concave surface having a radius of curvature greater than that of the convex surface so that the ribs have a thickness greater than the average thickness of the laminate. The laminate material adjacent to lateral boundaries of the ribs is in a tensionless state reversely curved relative to the rib curvature making the material between adjacent pairs of ribs generally flat. The rib pattern is preferably regular with a preferred average transverse spacing between adjacent ribs, measured peak to peak, of about 1-10 mm. The convex surfaces of the ribs can all be on the same side of the laminate or can alternate in series between opposite sides. The pattern of elongated ribs can be interrupted at longitudinally spaced loci to enhance the flexibility of the laminate and the laminate can have an undulating curvature when viewed from the side. A process and apparatus for making the ribbed cross-laminate by means of intermeshing grooved rollers are also disclosed.
Patent IL-108423-A0 (IL)
Title: Gamma camera with gain compensation
IPC: A61B19/00
Filed: 1994-01-25
Abstract: A gamma-camera comprising means for locating scintillations produced under the effect of gamma radiation in a scintillation crystal, the said location means comprising an array of photomultiplier tubes which are gain-controlled using calibrated light pulses, and a location circuit in which each photomultiplier tube (i) is connected, on the one hand, through a diode (Di) termed a resolution diode, to a weighting circuit (10i') comprising an array of resistors (R1i, R2i, R3i, R4i) connected to output adders (11) and, on the other hand, to a linearisation circuit (20i) supplying a signal It termed the linearity-threshold signal. According to the invention, the said linearisation circuit (20i) includes means for additionally supplying, for a period of time at least equal to the duration of the calibrated light pulses, a pulse (U) for blocking the said resolution diode (Di) with respect to the electrical pulses (Impi) delivered by the photomultiplier tube (i) in response to said light pulses. Application to nuclear medicine. <IMAGE>
Patent IL-114187-A0 (IL)
Title: Apparatus and methods for separating solids from flowing liquids or gases
IPC: E03F5/14
Filed: 1995-06-16
Abstract: PCT No. PCT/AU95/00351 Sec. 371 Date Mar. 24, 1997 Sec. 102(e) Date Mar. 24, 1997 PCT Filed Jun. 16, 1995 PCT Pub. No. WO95/35145 PCT Pub. Date Dec. 28, 1995An apparatus and method for separating material which includes solid and/or particulate matter from flowing liquid and/or gas. The apparatus includes a separation panel positioned in a fluid flow path, and the separation panel is housed in a separation chamber. Fluid can be introduced into the separation chamber by an inlet to establish a circular flow of the fluid within a confine of the separation panel, so material entrained in the fluid is trapped within the confine of the separation panel. The separation panel, separation chamber and inlet can be dimensioned and disposed such that as the apparatus operates, the flow of the fluid outside the separation panel is in a direction opposite to a direction of the flow of the fluid within the separation panel. The separation panel can include plural deflection means for deflecting material entrained in the fluid away from the openings, and the deflection means are generally opposed to a direction of the flow of the fluid, each opening having one of the deflection means associated therewith.
Patent IL-114829-A0 (IL)
Title: Biphenyl isoxazoel sulfonamide derivatives
IPC: A61P29/00
Filed: 1995-08-03
Abstract: Compounds of the formula <CHEM> inhibit the activity of endothelin. The symbols are defined as follows: R<1>, R<2>, R<3> and R<4> are each directly bonded to a ring carbon and are each independently     (a) hydrogen; (b) alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, aryloxy, aralkyl or aralkoxy, any of which may be substituted with Z<1>, Z<2> and Z<3>;   (c) halo;   (d) hydroxyl;   (e) cyano;   (f) nitro;   (g) -C(O)H or -C(O)R<5>;   (h) -CO2H or -CO2R<5>;   (i) -Z<4>-NR<6>R<7>;   (j) -Z<4>-N(R<1><0>)-Z<5>-NR<8>R<9>; or (k) R<3> and R<4> together may also be alkylene or alkenylene, either of which may be substituted with Z<1>, Z<2> and Z<3>, completing a 4- to 8-membered saturated, unsaturated or aromatic ring together with the carbon atoms to which they are attached; and the remaining symbols are as defined in the specification.
Patent IL-129749-A0 (IL)
Title: Texturizing compositions for use in fat blends in food
IPC: A23L33/20
Filed: 1997-11-03
Abstract: Fatty acid esters, such as the unsaturated fatty acid esters of sterols and/or stanols, are used as a replacement for a portion of the undesirable saturated and  trans -unsaturated fats used as structure giving hardstocks in edible foods such as margarines, mayonnaise, cooking oils, cheeses, butter and shortening. Because of the similarity in the crystallinity and physical properties of the esters to those of the undesirable hardstock fats, the substitution or replacement contributes favourably to the flavor, texture and other sensory properties of the foods. The fatty acid esters comprise at least 70 % of the structure giving hardstock.
Patent IL-133362-A0 (IL)
Title: Valve for aerosol container
IPC: B65D83/44
Filed: 1998-07-27
Abstract: The invention is directed to a valve for an aerosol container for dispersing a suspension or solution of a medicament in a liquid propellant contained therein. The valve comprises a valve body defining an aperture, a seal mounted at the aperture, and a valve stem having a dispensing passage. The valve stem being slideably moveable through the seal such that in a first position the valve is closed to prevent the medicament and propellant from entering the dispensing passage. The valve stem also being such that in a second position the valve is open to allow the substance to be dispensed through the dispensing passage. The valve seal characterized in that it is constructed from a nitrile-containing rubber and micronized fluorine-containing polymer.
Patent IL-133965-A0 (IL)
Title: Wake-up circuit for an electronic apparatus
IPC: H04B10/11
Filed: 1998-07-09
Abstract: A wake-up circuit for an electronic device comprises an input circuit (1) for receiving infrared signals and an amplifier (2) connected to the input circuit (1), the output of the amplifier being connected to a switching circuit (6) for switching on the device. To improve the signal/noise ratio it is provided that the input circuit (1) includes a parallel arrangement of at least two series arrangements of infrared detectors (7 to 10) as well as a parallel resonant circuit (11), and that the amplifier is a bandpass amplifier (2) the output of which is connected to a signal detector to which the switching circuit (6) is connected.
Patent IL-137273-A0 (IL)
Title: Process for preparing alkoxytriazolinones
IPC: C07D249/12
Filed: 1999-01-30
Abstract: Alkoxytriazolinones of the formula (I) [known for example as intermediates for preparing agrochemically active compounds]wherein R represents an alkyl group, an alkenyl group, an alkinyl group, a cycloalkyl group, a cycloalkylalkyl group, an aryl group or an arylalkyl group, any of which may be substituted, are prepared by reacting a) thioimidodicarboxylic diesters of the general formula (II)  wherein R is as defined above and R1 represents an alkyl group, an arylalkyl group or an aryl group, any of which may be substituted, with b) hydrazine, hydrazine hydrate or an acid adduct of hydrazine. The reaction is conducted i) in the presence of a diluent and, optionally, in the presence of a basic reaction auxiliary, and ii) at temperatures between -10 DEG  C. and +100 DEG  C.