baber/WOPTO huggingface dataset:
Patent CA-3002877-A1 (CA)
Title: Composes isoindoline, azaisoindoline, dihydroindenone et dihydroazaindenone utilises comme inhibiteurs de mnk1 et mnk2
Inventor: SPRENGELER PAUL A
IPC: C07D403/12
Filed: 2016-10-28
Abstract: La présente invention concerne la synthèse, des formulations pharmaceutiquement acceptables et des utilisations de composés selon la Formule I, ou un stéréo-isomère, un tautomère ou un sel pharmaceutiquement acceptable de ceux-ci. Pour les composés de Formule I, A1, A2, A3, A4, A5, W1, Y, R1, R2, R3, R4, R5, R6a, R6b, R7, R8, R8a, R8b, R9, R9a, R9b, et R10 et l'indice « n » sont tels que définis dans la description. Lesdits composés de Formule I selon l'invention sont des inhibiteurs de Mnk et s'avèrent utiles dans un grand nombre d'applications thérapeutiques, notamment mais pas exclusivement dans le traitement d'une inflammation et de divers cancers.
Patent CA-3002899-A1 (CA)
Inventor: MONIOT REMI
IPC: C10G2/00
Filed: 2015-10-26
Abstract: The process comprises : - introducing the feed flow in a synthesis gas generation unit to form a synthesis gas flow and introducing the synthesis gas flow in a Fischer-Tropsch synthesis unit - at least partially removing carbon dioxide from a first flow formed from a Fischer-Tropsch tail gas flow to form a carbon dioxide depleted flow; - forming a tail gas recycle flow from the carbon dioxide depleted flow; - introducing the tail gas recycle flow in the synthesis gas generation unit and/or in the synthesis gas flow. The process comprises adjusting the carbon dioxide content in the tail gas recycle flow to control the hydrogen to carbon monoxide molar ratio in the synthesis gas flow to a target hydrogen to carbon monoxide molar ratio.
Patent CA-3003225-A1 (CA)
Title: A system with drinks preparation machine, a method and computer program for its activation
Inventor: MATHURE GAURABH
IPC: G07F13/06
Filed: 2016-11-14
Abstract: A method for operating a beverage preparation machine (1) is used to produce a total product from a first sub-product, at least one second sub-product, and a third sub-product. The method has at least the following steps:  detecting a user input for specifying three quantities (21, 22, 23), wherein a graphical presentation of the quantities (21, 22, 23) is displayed with a respective quantity display (41, 42, 43) per quantity, the size of the quantity display (41, 42, 43) is substantially proportional to the corresponding quantity (21, 22, 23), and the size of at least one of the quantity displays (41, 42, 43) and thus the corresponding quantity (21, 22, 23) can be adapted according to a user input; and  producing the total product as a combination of the three sub-products with quantities corresponding to the specified quantities (21, 22, 23).
Patent CA-3004781-A1 (CA)
Title: Procede de production d'une peinture multicouche
Inventor: CORTEN CATHRIN
IPC: C09D5/00
Filed: 2016-06-03
Abstract: La présente invention concerne un procédé permettant de réaliser une peinture multicouche sur un substrat métallique. Selon ce procédé, une couche de peinture de base ou plusieurs couches de peinture de base directement consécutives sont produites directement sur un substrat métallique revêtu d'une couche électrophorétique de peinture durcie, une couche de vernis transparent est produite directement sur la couche de peinture de base ou sur la couche de peinture de base supérieure des couches consécutives, et ensuite la ou les couches de peinture de base et la couche de vernis transparent sont durcies conjointement. Le procédé selon l'invention est caractérisé en ce qu'au moins une peinture de base utilisée pour la production des couches de peinture de base comporte au moins une dispersion aqueuse (wD) contenant un polymère dont la fabrication comprend la polymérisation en émulsion radicalaire successive de trois mélanges (A), (B) et (C) de monomères oléfiniquement insaturés.
Patent CA-3005862-A1 (CA)
Inventor: YANG QIANG
IPC: C07D403/06
Filed: 2016-11-17
Abstract: L'invention concerne un procédé de préparation de 4-((6-(2-(2,4-difluorophényl)-1,1-difluoro-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile.
Patent CA-3007024-A1 (CA)
Inventor: LENG LUHAO
IPC: A47C19/20
Filed: 2017-02-23
Abstract: Disclosed are a structure for connecting a post and a beam (1) of a bunk bed and a bunk bed using the structure. A support tube (2) is located above the beam (1). A connection tube (3) is located below the beam (1). One end portion of the beam (1) is provided with an insertion connection portion (4) used to connect the support tube (2) and the connection tube (3). The insertion connection portion (4) and the support tube (2) have a pair of slanted surfaces disposed opposite to each other. When the support tube (2) and the insertion connection portion (4) are connected by insertion, the slanted surface (5-1) of the insertion connection portion (4) tightly fits the slanted surface (5-2) of the support tube (2). The insertion connection portion (4) and the connection tube (3) have a pair of slanted surfaces disposed opposite to each other. When the connection tube (3) and the insertion connection portion (4) are connected by insertion, the slanted surface (5-1) of the insertion connection portion (4) tightly fits the slanted surface (5-2) of the connection tube (3). When the support tube (2) and the insertion connection portion (4) are connected by insertion, the connection between the insertion connection portion (4) and the support tube (2) becomes tighter with an increasing pressure. When the connection tube (3) and the insertion connection portion (4) are connected by insertion, the connection between the insertion connection portion (4) and the connection tube (3) becomes tighter with an increasing pressure. The insertion connection portion (4), the connection tube (3), and the support tube (2) can be fixed without using bolts, and assembly and disassembly thereof can be carried out quickly and conveniently.
Patent CA-3008526-A1 (CA)
Inventor: CHABROL CLAUDE
IPC: A61N5/06
Filed: 2016-12-07
Abstract: The invention relates to a device comprising: a light source (103) mounted in a housing (109), the housing (109) comprising a transparent window (111) opposite the light source (103); an optical fiber (101) fitted with a connector (113) suitable for detachably engaging with the housing (109) to retain an input surface (101a) of the optical fiber (101) opposite the light source (103) via the window (111); and an interface element (301) made of a transparent elastomeric material suitable, in the connected position, for being retained so as to be compressed between the window (111) and the input surface (101a) of the optical fiber (101).
Patent CA-3010353-A1 (CA)
Inventor: MOENY WILLIAM M
IPC: E21B10/00
Filed: 2016-02-22
Abstract: A downhole drilling system is disclosed. The downhole drilling system may include a bottom-hole assembly having a pulse-generating circuit and a switching circuit within the pulse-generating circuit, the switching circuit comprising a solid-state switch. The downhole drilling system may also include a drill bit having a first electrode and a second electrode electrically coupled to the pulse-generating circuit to receive a pulse from the pulse-generating circuit.
Patent CA-3013834-A1 (CA)
Inventor: ALI RANA
IPC: C10L1/233
Filed: 2017-02-09
Abstract: A fuel composition for a spark-ignition internal combustion engine comprises a non-metallic octane-boosting additive. The non-metallic octane-boosting additive is an additive which, when used at a treat rate of 0.67 % by weight, increases the research octane number of a fuel by at least 1.8 whilst maintaining the T90 and/or the vapour pressure.
Patent CA-3014450-A1 (CA)
Title: System and method for advanced campaign management
Inventor: STUMPF MARK R
IPC: H04M3/00
Filed: 2017-01-20
Abstract: A system and method are presented for advanced campaign management in outbound dialing platforms. In a contact center environment, a dialing campaign may be configured such that the outbound dialing platform modifies its behavior automatically throughout the dialing campaign as conditions change. Dialing campaigns may be constructed from groups, which are organized into a campaign sequence. As the campaign sequence flows between groups, details of the campaign may be monitored and evaluated by the platform. Group transitions may be initiated based on activation triggers. In an embodiment, campaign sequences may also be automatically transitioned to new campaign sequences, paused, or reset based on activation triggers. A transition may also be initiated by manual override of the platform.
Patent CA-3016242-A1 (CA)
Inventor: KOHN STEVE
IPC: B65D30/00
Filed: 2018-08-31
Abstract: A method for digital printing of single or multiple color graphics and/or text on flexible and semi-rigid packaging materials comprising: digitally pre-printing on a sheet or roll of paper, polyethylene or other material, or digitally post printing on a bag, pouch, or sheet of material by depositing a thin layer of ink or toner onto a packaging material surface to form an image, and then adhering the ink or toner to the packaging material surface by use of a fuser fluid, heat, UV curing process, or any combination.
Patent CA-3019310-A1 (CA)
Inventor: GORIAWALA QAUSARALI
IPC: B01D21/24
Filed: 2018-10-01
Abstract: A screen decanter for decanting liquid from a reservoir, comprising at least one rack comprising screens and baffles forming the sides of a cavity; a frame attached to the screens and baffles and providing a barrier so that liquid cannot pass from outside into the cavity without passing through the screens; a patterned perforated drain pipe inside the cavity and leading to an opening through which liquids may drain out from the cavity. The pattern of the openings counteracts the hydrostatic head within the rack such that flow through the screens is uniform at all depths of immersion in the liquid reservoir. Preferably, the screens have a porosity of about 50 micrometers.
Patent CA-3019995-A1 (CA)
Inventor: BOYD CLARK D
IPC: H01L35/34
Filed: 2017-10-09
Abstract: A method for forming a unique, environmentally-friendly micron scale autonomous electrical power source is provided in a configuration that generates renewable energy for use in electronic systems, electronic devices and electronic system components. The configuration includes a first conductor with a facing surface conditioned to have a low work function, a second conductor with a facing surface having a comparatively higher work function, and a dielectric layer, not more than 200 nm thick, sandwiched between the respective facing surfaces of the first conductor and the second conductor. The autonomous electrical power source formed according to the disclosed method is configured to harvest minimal thermal energy from any source in an environment above absolute zero. An autonomous electrical power source component is also provided that includes a plurality of autonomous electrical power source constituent elements electrically connected to one another to increase a power output of the autonomous electrical power source.
Patent CA-3021946-A1 (CA)
Inventor: MAZACK MICHAEL J
IPC: G16H50/20
Filed: 2018-10-24
Abstract: The invention relates to systems and methods for estimating a patient urea level at any arbitrary time during dialysis treatment. The systems and methods use either one or more urea sensors or any two of a pH sensor, ammonia sensor, and ammonium sensor to determine an amount of urea removed by a dialysate regeneration system. The systems and methods use the amount of urea removed by the dialysate regeneration system to estimate the patient urea level.
Patent CA-3024154-A1 (CA)
Title: Element roulette a semi-blocage et cale de verrouillage
Inventor: GROSZ GREGORY CHRISTOPHER
IPC: E21B10/42
Filed: 2017-06-16
Abstract: On décrit un trépan comprenant: un corps de trépan duquel s'étendent une ou plusieurs lames; une pluralité de couteaux fixés à la lame ou aux lames; et un assemblage d'éléments de roulette positionné à l'intérieur d'une cavité définie sur le corps de trépan. L'assemblage d'éléments de roulette comprend un élément roulette pouvant tourner à l'intérieur de la cavité autour d'un axe de rotation, et un dispositif de retenue extensible à l'intérieur d'une fente de retenue définie dans la cavité pour y fixer l'élément roulette. Le dispositif de retenue et la cavité entourent ensemble plus de 180° mais moins de 360° d'une circonférence de l'élément roulette tout en laissant apparaître une largeur axiale entière de l'élément roulette. Le dessus du dispositif de retenue présente une partie saillante qui s'étend dans une zone décalée de la fente de retenue lorsque la première pièce de retenue est insérée dans la fente de retenue dans une première direction et déplacée à l'intérieur de la fente de retenue dans une seconde direction.
Patent CA-3024769-A1 (CA)
Inventor: KAATRASALO TERO
IPC: E02F3/36
Filed: 2017-05-26
Abstract: L'invention concerne une structure d'un dispositif de rotation, un dispositif de rotation et une machine forestière. Le dispositif de rotation comprend - une première partie de corps interne (12) comprenant des premiers conduits (26) fixés à la première partie de corps interne (12) pour conduire un milieu de pression à travers la première partie de corps interne (12), - une seconde partie de corps externe (14), agencée au moins partiellement autour de la première partie de corps interne (12) complètement en rotation, comprenant des raccordements (28) fixés à la seconde partie de corps externe (14), - des seconds conduits (30) agencés pour conduire le milieu de pression dudit premier conduit (26) auxdits raccordements (28), - un conduit axial (16) permettant de conduire des conducteurs électriques (56) à travers la première partie de corps interne (12) et comprenant deux extrémités (16.1, 16.2), - des moyens de support (20) agencés pour permettre à la seconde partie de corps externe (14) de tourner par rapport à la première partie de corps interne (12) et vice-versa, et - des moyens de suspension (90) permettant de suspendre la structure (10) du dispositif de rotation (1) à partir d'une flèche (2). La structure (10) selon l'invention comprend des moyens de fixation (22) permettant de fixer un dispositif de rotation (24) actionné par milieu de pression à entraînement direct à la structure (10) de façon coaxiale afin de transmettre un couple. Dans la structure (10) se trouve un conduit axial (16) s'étendant à partir du moyen de suspension (90) à travers la structure (10) et le dispositif de rotation (24) fixé à celui-ci pour porter des conducteurs électriques (56).
Patent CA-3026510-A1 (CA)
Inventor: MANGELSDORF DAVID J
IPC: C07K14/50
Filed: 2017-05-24
Abstract: The present invention relates to the treatment of secretory disorders, and provides novel methods of treatment of these disorders comprising the administration of fibroblast growth factor 21 (FGF21) or derivatives thereof. The methods of the invention are useful in conditions including exocrine pancreatic insufficiency (EPI), for example EPI resulting from cystic fibrosis, alcoholism, pancreatitis, pancreatic cancer, gallstones, celiac disease, high triglycerides, or lupus. The methods of the present invention find further utility in the treatment of salivary flow disorders, for example Sjorgen's syndrome, and the prevention of EPI or pancreatitis resulting from surgical procedures.
Patent CA-3026751-A1 (CA)
Inventor: PAPINI FRANCESCO
IPC: H02K17/42
Filed: 2017-06-13
Abstract: Systems and methods are provided for powering a pipeline inspection system.  The system includes an induction generator extending along a radially curved plane. The induction generator having an outer surface and an opposing inner surface. The outer surface is positioned proximate to an inner surface area of a pipeline. The system also includes a controller circuit configured to generate a plurality of periodic waveform signals. The plurality of periodic waveform signals are received by the induction generator. The induction generator is configured to generate active power that charges an electric power source based on the plurality of periodic waveform signals and the inner surface area.
Patent CA-3026965-A1 (CA)
Title: Vetement moule en fibres naturelles
Inventor: TURLAN-VAN DER HOEVEN MANON
IPC: A41C3/00
Filed: 2017-06-07
Abstract: L'invention concerne un stratifié en tissu moulé, lequel stratifié comprend des première et seconde couches de tissu, chaque couche de tissu comprenant au moins 80 % de fibres naturelles, et une couche à motifs d'élastomère à mémoire de forme durci moulée entre les première et seconde couches de tissu. La couche à motifs de l'élastomère à mémoire de forme durci est une couche continue de l'élastomère à mémoire de forme durci définissant une multiplicité d'ouvertures par centimètre carré de la couche à motifs, les ouvertures étant dépourvues d'élastomère à mémoire de forme durci. La fabrication du stratifié en tissu moulé met en uvre la disposition d'une couche à motifs d'un élastomère à mémoire de forme non durci sur une première couche de tissu, la mise en contact de la couche à motifs avec une seconde couche de tissu pour produire un sous-ensemble de tissu, la mise en contact du sous-ensemble de tissu avec une surface d'un moule chauffé, et le moulage du sous-ensemble de tissu de façon à ce qu'il se conforme à la forme du moule. Le stratifié en tissu moulé fait typiquement partie d'un vêtement.
Patent CA-3029011-A1 (CA)
Inventor: SPRACHMAN MELISSA M
IPC: C12Q1/68
Filed: 2017-05-22
Abstract: A composition for use in extending a molecular chain includes a carrier group and a payload group. The carrier group comprising a signaling group and a blocking group. A first bond bonds the payload group to the carrier group and a second bond bonds the signaling group to the blocking group. The first and second bonds are selectively cleavable such that the first bond is cleavable without cleaving the second bond. The payload group is to be attached to the molecular chain, while the blocking group is to block further attachments to the molecular chain once the payload group has been attached. The signaling group comprises a photon emitter that emits a signature photon in response to interrogation by an interrogatory photon. The carrier group transitions from a loaded state to an empty state upon cleavage of the first covalent bond.
Patent CA-3030326-A1 (CA)
Inventor: LEE HYECK-HEE
IPC: B05B11/00
Filed: 2017-06-01
Abstract: The invention relates to a pump head which dispenses a metered quantity of fluid. The invention also relates to a metering device which can be designed, for example as a squeeze bottle, and the metering device comprises a claimed pump head.
Patent CA-3034348-A1 (CA)
Inventor: PATOLSKY FERNANDO
IPC: A61B5/145
Filed: 2017-08-22
Abstract: A system for monitoring at least presence of a bioanalyte. The system comprises: a substrate having a skin contact surface, a microneedle outwardly protruding from the skin contact surface, a sensing complex positioned in the microneedle, and a circuit attached to the substrate. The sensing complex can comprise a nanostructure modified by a functional moiety covalently attached thereto, and an affinity moiety effective to react specifically with the bioanalyte to produce a reaction product. The circuit can apply voltage to the nanostructure and monitor changes in an electrical property of the nanostructure responsively to reaction between the reaction product and the functional moiety.
Patent CA-3034631-A1 (CA)
Title: Free radical generation device and methods thereof
Inventor: MOHANTY PRAVANSU S
IPC: H05H1/46
Filed: 2017-09-05
Abstract: A barrierless device and method for generating streamer discharge is provided including solid/liquid electrodes for free radical generation at high efficiency. A first electrode, including periodically positioned discharge ignition tips is deposed in proximity to a second electrode, creating a discharge gap with no dielectric barrier layer in between. The discharge gap includes an inlet and an outlet. Streamers with proximity constraints emerge from the first electrode and propagate through the discharge gap towards the second electrode by supplying either positive or negative pulse voltage to the first electrode, resulting in interaction of the streamer heads with the discharge gas and generation of radicals. Optionally, the second electrode is a liquid which interacts with the streamer head to generate additional radicals. The device can either be used to cause fast chemical reaction within the discharge gap or the generated radical gas can be removed for utilization outside the discharge gap.
Patent CA-3038194-A1 (CA)
Title: Cartouche de dissuasion d`animal combinee et dispositif de transport
Inventor: HAIGH DUSTIN
IPC: F41H9/10
Filed: 2019-03-27
Abstract: Une cartouche de dissuasion contre les animaux comprend un récipient sous pression contenant un agent dissuasif contre les animaux et un assemblage de buse comprenant une bride, un actionneur actionné par une pression vers le bas et une buse pour libérer lagent dissuasif contre les animaux du récipient sous pression avec un dispositif de support. Le dispositif de support comprend une structure de montage pour linstallation sur un objet, un récepteur pour recevoir lassemblage de buse de la cartouche de dissuasion contre les animaux, une goupille dactionneur pouvant passer dune position rentrée éloignée de lactionneur à une position sortie enfonçant lactionneur, et un câble logé dans une gaine. Le récepteur comprend un profil de raccord qui reçoit la bride en raccord dinterférence. Une extrémité du câble est raccordée à la goupille dactionneur et lautre extrémité est raccordée à un actionneur à main qui applique une force de compression sur le câble par rapport à la gaine pour déplacer la goupille dactionneur en position sortie.
Patent CA-3038996-A1 (CA)
Inventor: HARADA MASARU
IPC: D02G3/04
Filed: 2017-09-27
Abstract: A flame resistant knitted fabric having excellent flame resistance is provided formed from non-melt fibers A, which have a high temperature shrinkage of less than or equal to 3%, and thermoplastic fibers B, which have an LOI value conforming to JIS K 7201-2 (2007) of greater than or equal to 25 and have a melting point lower than the ignition temperature of the non-melt fibers A, characterized in that the elongation at break of the yarns configuring the knitted fabric are greater than 5%, and, of the projected area in the complete knitted fabric, the surface area of the non-melt fibers A is greater than or equal to 10%, the surface area of the thermoplastic fibers B is greater than or equal to 5%, and the thickness, according to the method A in JIS L 1096 (2010), is greater than or equal to 0.08 mm.
Patent CA-3039014-A1 (CA)
Inventor: JANTZ DEREK
IPC: C07K14/705
Filed: 2017-10-04
Abstract: The present disclosure provides novel co- stimulatory domains useful in genetically- modified cells to promote cell proliferation and/or promote cytokine secretion after antigen recognition. For example, disclosed herein are genetically-modified cells comprising a chimeric antigen receptor or an inducible regulatory construct incorporating the co- stimulatory domains disclosed herein. Also disclosed herein are plasmids and viral vectors comprising a nucleic acid sequence encoding the co-stimulatory domains, and methods of administering compositions comprising the novel co-stimulatory domains to subjects in order to reduce the symptoms, progression, or occurrence of disease, such as cancer.
Patent CA-3040409-A1 (CA)
Inventor: LAWHORN THOMAS
IPC: A61M1/00
Filed: 2017-02-16
Abstract: Methods and systems for managing patient compliance with a treatment are disclosed. An example method can comprise receiving data indicative of a time on active therapy. The method can comprise receiving data indicative of a pressure associated with the time on active therapy. The method can further comprise determining a patient compliance factor based on the data indicative of the time on active therapy and the data indicative of the pressure associated with the time on active therapy. The method can comprise determining a graphical object modifier based on the patient compliance factor and displaying a graphical object based on the graphical object modifier.