baber/WOPTO huggingface dataset:
Patent EP-2363494-A1 (EP)
Inventor: KLOESEL ROLAND
IPC: C12N15/87
Filed: 2008-11-24
Abstract: Composition for transfection, comprises: (a) a non-viral gene delivery system containing cationic lipid, cationic polymer or a cationic protein, a compound, which exhibits a DNA and/or RNA-binding domain, and/or a compound; and (b) an agent for partial suppression and/or activation of innate intracellular and/or intercellular immune defense comprising e.g. an antibody against toll-like receptor (TLR) 1 to TLR 13 and cytokine receptor or cytokine receptor-antagonist and an inhibitor of the kinase of mitogen-activated protein kinase 1 (MEK1) and/or MEK2. Composition for transfection, comprises: (a) a non-viral gene delivery system containing a cationic lipid, a cationic polymer or a cationic protein, a compound, which exhibits a DNA and/or RNA-binding domain and activates receptor-mediated endocytosis or a membrane transfer, and/or a compound, which is covalently bonded to DNA and/or RNA and activates receptor-mediated endocytosis or a membrane transfer; and (b) an agent for at least partial suppression and/or activation of the innate intracellular and/or intercellular immune defense comprising an antibody against toll-like receptor (TLR) 1 to TLR 13, an antibody against a cytokine receptor or a cytokine receptor-antagonist, an inhibitor of the kinase of mitogen-activated protein kinase/extracellular signal-regulated kinase 1 (MEK1) and/or MEK2, an agonist for TLR7 and/or TLR8 comprising bropirimine, imidazoquinoline, thiazoloquinoline and/or guanosine analogs. Independent claims are included for: (1) a kit of parts for transfection, comprising the composition; and (2) a procedure for improving the transfection output of non-viral gene delivery system comprising treating the cells with (b), before and/or during the transfection and inserting the transfection genetic material into the cells or treating the cells with (b), before, during and/or after and inserting modified or unmodified small interfering RNA (siRNA) into the cells. ACTIVITY : CNS-Gen.; Respiratory-Gen.; Muscular-Gen.; Metabolic; Antilipemic; Hemostatic; Antianemic; Cytostatic; Virucide; Ophthalmological; Neuroprotective; Antiinflammatory. MECHANISM OF ACTION : Gene therapy.
Patent EP-2357101-A1 (EP)
Title: Sliding door device
Inventor: NOMURA DAISUKE
IPC: B60H1/00
Filed: 2011-02-16
Abstract: A sliding door device (S) includes a frame case (1) that includes an opening through which an air flow passes, a slide door (2) that is moved relative to the opening to adjust an aperture ratio of the opening, a shaft (5) that is disposed at an upstream side of the slide door when viewed along the flowing direction of the air flow, and moves the slide door, and a windbreak member (6) that blocks a gap between the shaft and the slide door.
Patent EP-2570655-A1 (EP)
Inventor: KLINNER UWE
IPC: F03D7/02
Filed: 2011-09-16
Abstract: The component (1) has an adjusting mechanism arranged in an inner area of the component, and a circular or cylinder-shaped housing comprising openings, where the component is positioned between blades (54) or blade shafts (55). The housing has an upper housing or intermediate disk and a lower housing or intermediate disk. An assembly designed as a hydraulic or electrical drive is coupled to the housing. Roller bearing rings are rotated opposite to each other, and roll on rolling bodies. A casing comprising a reinforced steel or plastic wall is arranged in the inner area of the component. An independent claim is also included for a small wind energy plant.
Patent EP-2450167-A1 (EP)
Inventor: JAAFAR AHMED
IPC: B26D1/553
Filed: 2011-11-08
Abstract: The thermal cutting device has a frame-shaped or bow-shaped holder (13) equipped with a cutting-wire device for a cutting-wire (21) between two spaced areas of the holder positioned against each other. A wire tensioning device (1) is provided for adherence of the required wire tension of each cutting-wire. One or multiple cutting-wires are switched-on electrically by the cutting-wire device insulated in an electric circuit loaded by an electric energy source.
Patent EP-2489646-A1 (EP)
Inventor: TISCHER WERNER DR RER NAT
IPC: C04B28/02
Filed: 2011-12-19
Abstract: Producing a photocatalytically active dry concrete mix, is claimed. The dry concrete mix is mixed together as a concrete base formulation for producing concrete, preferably for producing a molded brick, consisting of several components including at least one binding agent, preferably cement, and at least one additive or filler, preferably sand, and where, at least one photocatalytically active material is added to the dry concrete mix, preferably is mixed with this, where the photocatalytically active material is added to the dry concrete mix irrespective of the binding agent.
Patent EP-2492831-A1 (EP)
Inventor: CHEN CHUN-YU
IPC: G16H40/63
Filed: 2011-02-10
Abstract: The present invention relates to a biomedical device with near field communication (NFC) function and a method thereof for user identification, biomedical data measurement, biomedical data upload/download, biomedical data management, and remote medical care, the biomedical device comprises: a measuring unit, a environment sensing unit, a data transforming unit, a micro control unit, a memory unit, a smart card unit, a display unit, and a near field communication unit, wherein by way of near field communication unit, the biomedical device is able to communicate with a portable device and a user individual information and the relative biomedical data thereof can be transmitted to the portable device, such that multi men are allowed for using the identical biomedical device and the situation about misrecording and misjudging of data would not be occurred; moreover, through the portable device, the biomedical data can be uploaded to a cloud server and a user history data and an optimized setting data for personalization biomedical device can be downloaded from the cloud server.
Patent EP-2364684-A1 (EP)
Inventor: MORIARTY JOSHUA J
IPC: A61G7/00
Filed: 2011-03-09
Abstract: A caregiver assist device (80) for use with a parent support apparatus (40) is disclosed. The caregiver assist device including a support structure (84), a boom (120), a helper belt (320), and a constant force spring assembly (270). The boom extends from the support structure over the patient support apparatus. The helper belt is supported along the boom and has a first end and a second end. The constant force spring assembly includes a constant force spring coupled between the support structure and the end of the helper belt so that a constant counterbalancing force is applied to the helper belt in response to a patient force being applied to the second end of the helper belt.
Patent EP-2386976-A1 (EP)
Inventor: HENNINGS LENNART
IPC: G06F3/048
Filed: 2011-05-11
Abstract: The method involves displaying a touch-sensitive reactivation icon (8) in a visually defined field of a screen. The reactivation icon is drawn with a touching gesture in a previously locked region of a touch screen (7), where the release of display functionality is activated. The release of the reactivation icons is activated by the functionalities retrieved on the screen. An independent claim is also included for a mobile terminal, particularly a mobile phone.
Patent EP-2347722-A1 (EP)
Inventor: WENCHELL TOM
IPC: A61B17/072
Filed: 2002-10-04
Abstract: A surgical stapling device for sequentially applying a plurality of fasteners to body tissue and simultaneously incising tissue is provided. The surgical stapling device is adapted to receive disposable loading units having staples in linear rows whose length can be between about 30 mm and 60 mm. The disposable loading unit includes a proximal body portion, a mounting assembly and a tool assembly. The mounting assembly is secured to the proximal end of the tool assembly and pivotally mounted about a pivot axis to the distal end of the proximal body portion. A support member or blow-out plate assembly is positioned on opposite sides of the pivot avis and extends between the proximal body portion and the mounting assembly. An axial drive assembly is slidably positioned between the support members and is translatable through the cartridge assembly to eject staples from the cartridge assembly. The support members prevent outward buckling of the axial drive assembly during actuation of the device especially when the tool assembly is articulated. Preferably, a protrusion is provided in the proximal body portion of the disposable loading unit at a position to frictionally engage an articulation link. Engagement between the protrusion and the articulation link retains the articulation link at a fixed position within the proximal body portion to maintain the tool assembly in a desired orientation until a predetermined axial force is applied to the articulation link. The disposable loading unit also preferably includes a locking member which is operably connected to the axial drive assembly. The locking member provides an audible and/or tactile indication that the device has been actuated.
Patent EP-2524852-A1 (EP)
Inventor: BAIKER STEFAN
IPC: B61L1/18
Filed: 2011-05-17
Abstract: The method involves dividing a track section (nminus1,n,nplus1) in one or more sectors (S1 to Sz), where a response module is connected or interposed between two rail sections (An,Bn). The response module changes individually by signals supplied from a measuring device. The measuring device checks the change of signals or individual response signals, and assigns a corresponding allocation status. The measuring device (10n,10nplus1) is designed as a transmitting unit (11) which emits an interrogation signal in the form of a temporarily applied direct current voltage. An independent claim is included for a system for monitoring a track section, on which rail vehicles, such as passenger trains and freight trains are associated.
Patent EP-2447036-A1 (EP)
Inventor: FORSTHÖVEL JOCHEN
IPC: B29C31/00
Filed: 2011-07-08
Abstract: The plant (A) has a melt-producing upstream plant section interlocked with a preform producing injection molding plant section (2) to form a plant block (B) for direct processing of a produced melt to preforms (P) in the injection molding plant section for deriving process alteration strategies and preform qualifying strategies and a combination of both the strategies. An inline measurement station (9) with an evaluating device (21) is provided between the interlocked plant sections at an interface (4) for providing a quality parameter of a melt measured during the operation of the plant. An independent claim is also included for a method for continually producing preforms for plastic containers for filling of foodstuffs.
Patent EP-2409708-A1 (EP)
Inventor: BARBEAU DONALD L
IPC: A61P35/00
Filed: 2011-07-20
Abstract: The present invention relates to pharmaceutical compositions containing tumor-selective targeted inhibitor glycoconjugates. These bioconjugates are ALK5 inhibitors covalently bound to biocompatible carrier molecules which selectively target and specifically bind to Muc4 that is overexpressed on a variety of tumor cell types. The ALK5 inhibitors are conjugated to tumor targetable glycans through a covalent linker. Preferably the acid-labile linker is designed to be stable in plasma and releases pharmacologically active inhibitors through acid-catalyzed hydrolysis in the acidic environment of the target tumor where the inhibitor activity is restored. Because the glycoconjugates are stable at physiological pH and in plasma, they advantageously reduce undesirable systemic ALK5 inhibitor activity; however, the preferable glycoconjugates are acid-labile conjugates that can be hydrolyzed upon reaching the more acid environment of the tumor.
Patent EP-2428697-A1 (EP)
Inventor: RIMOUX CHRISTOPHE
IPC: B60G15/06
Filed: 2011-09-06
Abstract: The stop has a bearing (12) comprising an upper washer (14) and a lower washer (16) defining a rolling path on which rolling bodies (18) are rolled, where the lower washer integrates a support interface against an upper end of a helical spring (22). A rigid fixing element (26) fixes a MacPherson strut to a superstructure of a vehicle. An impact stop (30) comprises an annular strip (36) placed in an annular volume (38) delimited axially by a lower bearing (40) integrated to the upper washer and an upper bearing integrated to a rigid element. An independent claim is also included for a MacPherson strut comprising a telescopic shock absorber.
Patent EP-2450393-A1 (EP)
Inventor: FUJII HARUKA
IPC: C09D183/04
Filed: 2011-10-17
Abstract: A silicone resin is obtained by allowing a cage octasilsesquioxane having a group represented by formula (1) below, to react with an alkenyl group-containing polysiloxane containing an alkenyl group having a molarity smaller than the molarity of the hydrosilyl group of the cage octasilsesquioxane in the presence of a hydrosilylation catalyst:
     
(where R 1  represents a monovalent hydrocarbon group, R 2  represents hydrogen or a monovalent hydrocarbon group, and the molar ratio of monovalent hydrocarbon group: hydrogen in R 2  in the cage octasilsesquioxane as a whole is, as an average value, in a range of 6.5:1.5 to 5.5:2.5).
Patent EP-2415566-A1 (EP)
Title: Additional handle device
Inventor: EICHER ROSWITHA
IPC: B25F5/00
Filed: 2008-10-01
Abstract: The device has an auxiliary handle (14), and an absorption device (16) that includes a counter-oscillation unit (18) with a counter-oscillation element (20). The unit (18) has a stimulation unit (22) for stimulating the element to counter-oscillation in axial directions (24, 26), where the element is formed partly by a damping mass element (28). The stimulation unit has a sensor unit (30) for detecting an oscillation characteristic of a hand tool machine. The stimulation unit has an adjusting unit (34) for adjusting a stimulation characteristic for the element.
Patent EP-2456084-A1 (EP)
Inventor: SOBOTKA PETER
IPC: H04B3/54
Filed: 2011-11-23
Abstract: The disclosure relates to a meter for monitoring usage of power provided by a power transmission system to a site. The meter comprises: a communication module to generate communications carried over the system; a request manager module to process messages received from a head end of the system; a meter module connected to a power feed of the system; a connection manager module to evaluate readings and data and to generate connection signals for the meter in view of the readings; and a relay having a first position where the power is connected to the site and a second position where the power is disconnected, the relay being controlled by the connection signals. The connection manager module generates a first signal for the relay to disconnect the power when an over-voltage condition or an over-current condition on the system has been detected.
Patent EP-2463634-A1 (EP)
Inventor: FEMBOECK JOSEF
IPC: G01L3/22
Filed: 2011-11-30
Abstract: The stand has a measuring device (2) comprising a measuring sensor (1) for receiving test data. A rechargeable energy storage part (3) i.e. electrically operating energy storage part, supplies electrical energy to operate the measuring device, and a supply unit (4) supplies the electrical energy in the energy storage part. The measuring device comprises an unwinding device (5) for rolling wheels (6) of a motor vehicle. The energy storage part is arranged between two rollers (7) of the unwinding device. An electric motor is utilized as an actuator for driving the rollers.
Patent EP-2469707-A1 (EP)
Inventor: KIRBY ESTELLE
IPC: G01S19/13
Filed: 2011-12-09
Abstract: The device has a time occupation rate estimating unit for estimating an occupancy time rate of pulses in a useful band. A characteristic quantity estimating unit estimates a characteristic quantity in a group of amplitude and power of sampled signals, where balances are determined by the occupancy time rate. A non-linear function module (6006) applies the balances to negative and positive differences resulting from comparison between the characteristic quantity and a set point value (6005). The function module provides signals integrated to a determined period to form a gain control signal.
Patent EP-2608236-A1 (EP)
Inventor: GERVING KARSTEN
IPC: H01H9/46
Filed: 2011-12-22
Abstract: The device has an arc driver arrangement provided for creation of a magnetic field, and an arc guidance arrangement for conducting a light arc between closed contacts (10,11) for a light arc control device (32) i.e. deion delete chamber. The arc guidance arrangement is divided into light arc routes (22, 23) for conducting the arc between the contacts. One of the arc routes is provided in a current direction and another arc route is provided in another current direction opposite to the former current direction. The latter arc route causes reversal of the arc and/or current.
Patent EP-2438956-A1 (EP)
Inventor: MIYATA NAOHIKO
IPC: A61M25/09
Filed: 2010-06-15
Abstract: Provided is a guidewire (1) including a core shaft (2)., an outer flexible tube (4), a stranded wire (3) that extends parallel to the core shaft, and a hollow stranded-wire coil (5) disposed in the outer flexible tube (4). The hollow stranded-wire coil (5) is formed of multiple strands and surrounds the distal end portion of the core shaft and the stranded wire. Distal ends of the hollow stranded-wire coil, the core shaft, and the stranded wire are joined (41) to a distal end of the outer flexible tube.
Patent EP-2594381-A1 (EP)
Inventor: KUNZE STEFFEN
IPC: B29C33/52
Filed: 2011-11-21
Abstract: The invention is related to a method for producing a mould core (1) by providing a removable mould core material (4) comprising separately at least one mould basic material and at least one binder, producing a tight core shell (2), filling the removable mould core material (4) into the tight core shell (2) and curing of the at least one binder of the at least one mould basic material inside the tight core shell (2). The invention is related as well to a mould core (1) made by said method.
Patent EP-2528919-A1 (EP)
Title: Compositions et procédés pour traiter la toxoplasmose, la cryptosporidiose et d'autres maladies associées aux protozoaires apicomplexa
Inventor: VAN VOORHIS WESLEY C
IPC: A61K31/4985
Filed: 2011-01-28
Abstract: La présente invention concerne des compositions et des procédés pour le traitement de la toxoplasmose, causée par le parasite eucaryote infectieux  Toxoplasma gondii  ( T. gondii ) et pour le traitement de la cryptosporidiose, causée par les parasites eucaryotes infectieux  Cryptosporidium 
 parvum  ( C. parvum ) et  Cryptosporidium homimus (C .  hominus) . En particulier, la présente invention concerne des compositions et des procédés pour inhiber les protéine kinases calcium-dépendantes de  T. gondii  ( Tg CDPK) ou les protéine kinases calcium-dépendantes de  C. parvum  et  C. hominus 
 (Cp DPK) en utilisant des inhibiteurs de pyrazolopyrimidine et/ou imidazo[1,5- a ]pyrazine, de formule (I), où les variables X, Y, Z, L, R 1 , et R 3  sont présentement définies.
Patent EP-2681146-A1 (EP)
Title: Commande de déverrouillage pour une porte de plancher d'ascenseur
Inventor: FIERRI GABRIEL
IPC: B66B13/20
Filed: 2011-03-03
Abstract: L'invention porte sur un système de commande pour désengager un verrou de sécurité d'une porte de plancher d'ascenseur, lequel système comprend : une unité d'actionnement linéaire (3) ; au moins une plaque (4) en un matériau élastiquement déformable ; au moins un câble d'actionnement (5) entre ladite unité d'actionnement et ladite plaque ; ladite unité d'actionnement (3), ladite plaque (4) et ledit câble d'actionnement (5) étant associés à la cabine d'ascenseur, le câble d'actionnement (5) induisant une configuration déformée (4 A ) de ladite plaque (4), et la plaque, dans une configuration déformée, se désengageant dudit verrou de sécurité, de façon à permettre à la porte de plancher de s'ouvrir.
Patent EP-2534009-A1 (EP)
Title: Appareil émetteur de son de notification pour véhicule
Inventor: YOSHINO HIDEO
IPC: B60Q5/00
Filed: 2011-02-07
Abstract: La présente invention concerne un appareil émetteur de son de notification pour véhicule. Ledit appareil est fondamentalement pourvu d'un dispositif émetteur de son (1) et d'un dispositif de commande de son de notification (12). Le dispositif émetteur de son émet un son de notification de mouvement à l'extérieur d'un véhicule pour informer une personne dans une zone qui entoure le véhicule que le véhicule se déplace à faible vitesse. Le dispositif de commande de son de notification (12) fait fonctionner le dispositif émetteur de son pour émettre sélectivement le son de notification de mouvement. Le dispositif de commande de son de notification (12) comprend une section de suppression de son de notification (16) et d'une section d'annulation de suppression (étape S54). La section de suppression de son de notification (16) empêche une émission du son de notification de mouvement par le dispositif émetteur de son (1). La section d'annulation de suppression (étape S54) annule une suppression d'émission de son de notification imposée par la section de suppression de son de notification (16) lorsqu'une vitesse du véhicule dépasse une vitesse de véhicule prescrite ou en fonction d'informations de position du véhicule.
Patent EP-2550136-A1 (EP)
Inventor: TRESSE DAVID
IPC: B26D7/27
Filed: 2011-03-24
Abstract: The invention relates to tooling for securing an equipment bracket (8) on a plastics skin (13) of a motor vehicle bodywork component, the equipment being of the type that has to be held, by the bracket (8) secured to the skin (13), opposite an orifice formed for this purpose in said skin, the tooling comprising a punching element (6), a stripper (7) in which the punching element can slide and a die (2) into which the punching element can penetrate in order to cut the skin and form the orifice. It comprises a bracket holder (2), that is to say a member shaped to receive the bracket (8), which is fitted around said bracket holder (2), and to hold it, simply on account of this fitting, in its final position with respect to the skin (13); the die (2b) is an end of the bracket holder (2) opposite the punching element (6); the tooling comprises securing means (5, 7) for securing the bracket (8) to the skin (13) when it is fitted on the bracket holder (2). The invention also relates to a securing method and a bodywork component.
Patent EP-2580028-A1 (EP)
Title: Vorrichtung zum greifen und anheben von gegenständen
Inventor: RIEDMAYER SIGURD A
IPC: B25J15/02
Filed: 2011-06-06
Abstract: Bei einer Vorrichtung (1), insbesondere zum Greifen und Anheben von Gegenständen (2) oder zum Spannen von Drähten und Seilen, wird das jeweilige Zwischenglied (13) als L-förmiger Führungsschlitten (21) oder als teleskopartig ineinander verschiebbar gelagerte Gleitelemente (41 und 42) ausgestaltet, wobei das erste freie Ende (22) des jeweiligen Führungsschlittens (21) oder des jeweiligen Gleitelementes (41, 42) mittels eines Kniehebels (15) trieblich mit der Antriebseinrichtung (6) verbunden ist, und wobei das zweite freie Ende (23) des jeweiligen Führungsschlittens (21) oder des jeweiligen Gleitelementes (41, 42) mit dem jeweiligen Greifarm (4 oder 5) oder dem Spannrohr gegenüberliegend zu dem Angriffspunkt (16) des Kniehebels (15) an dem Führungsschlitten (21) oder dem Spannrohr unmittelbar oder über Zwischenglieder (24, 25 und 27) in formschlüssiger Wirkverbindung und der Führungsschlitten (21) und der jeweilige Greifarm (4, 5) oder das Spannrohr an einem Führungsgestänge (14) linear verschiebbar gehalten sind.