baber/WOPTO huggingface dataset:
Patent CA-2700170-A1 (CA)
Inventor: AMACHER SHARON
IPC: C12N15/55
Filed: 2008-09-25
Abstract: Disclosed herein are methods and compositions for genomic editing of one or more genes in zebrafish, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Patent CA-2701124-A1 (CA)
Inventor: LAUFFER DAVID
IPC: A61K31/4439
Filed: 2008-09-30
Abstract: The present invention relates to compounds of formula I useful in the in-hibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compo-sitions in the treatment of proliferative disorders. Formula (I).
Patent CA-2702241-A1 (CA)
Inventor: CROCE CARLO M
IPC: C12Q1/68
Filed: 2008-10-10
Abstract: Methods and compositions for the diagnosis, prognosis and/or treatment of esophageal adenocarcinoma and Bar-rett's esophagus associated adenocarcinoma are disclosed, along with more markers where a difference is indicative of esophageal adenocarcinoma and squamous cell carcinoma, and/or Barrett's esophagus associated adenocarcinomas or a predisposition thereto.  The invention also provides methods and compositions of identifying anti-cancer agents therefor.
Patent CA-2703086-A1 (CA)
Inventor: SHIRATAKI HIRONOBU
IPC: C07K1/14
Filed: 2008-09-26
Abstract: Disclosed is a protein purification method for removing impurities from a mixed solution of a desired protein and the impurities, which comprises the step of filtering the mixed solution through a porous membrane which has a graft chain on the surface of each pore, wherein an anion exchange group is immobilized on the graft chain.
Patent CA-2704196-A1 (CA)
Inventor: SIESS THORSTEN
IPC: A61M60/82
Filed: 2008-10-27
Abstract: Des procédés et des systèmes permettent de faire circuler du sang au moyen d'une pompe miniature sans purge. Dans un mode de réalisation, une pompe est apportée qui peut comprendre un corps comprenant un rotor et un stator à l'intérieur d'une unité d'entraînement. Dans ledit mode de réalisation, la pompe peut établir un flux sanguin principal à travers l'espace situé entre l'unité d'entraînement et le corps, et un flux sanguin secondaire entre le rotor et le stator. Dans un autre mode de réalisation, il est apporté un procédé d'introduction de la pompe dans le corps et de circulation du sang au moyen de la pompe de l'invention.
Patent CA-2704255-A1 (CA)
Inventor: COOPER JACK R
IPC: B62D5/07
Filed: 2001-08-07
Abstract: A connector (75) for interconnecting a conduit in a fluid communicating manner with a liquid conveying means is provided. The connector is characterized by a first hollow cylindrical portion (76) for insertion into and for a crimped connection to said liquid conveying means, and a second hollow barbed or ridged portion (77) having barbs or ridges (78) thereon for insertion into and connection to said conduit.
Patent CA-2704486-A1 (CA)
Inventor: LERCH HELMUT
IPC: A45F5/02
Filed: 2008-10-30
Abstract: In a weapon holster with adjustable draw angle, in particular for hand firearms, comprising a holster web for fastening the holster to a belt, a coupling or the like and a holster receptacle for holding a weapon, in particular a hand firearm, wherein the holster web and the holster receptacle are connected together and can rotate about an axis of rotation such that the draw angle defined by the relative position between the holster web and the holster receptacle can be adjusted, latch protrusions between the holster web and the holster receptacle and latch depressions that are partially comple-mentary to said protrusions are provided in which the latch protrusions enga-ge for fixing various draw angles, wherein the adjustment of the draw angle is only accomplished by applying a torque that releases the latching protrusions from the latch depressions and rotating the holster web and holster re-ceptacle about the axis of rotation in opposite directions, and wherein the torque is adjustable.
Patent CA-2705040-A1 (CA)
Inventor: MASSAD JOSEPH H
IPC: A61C13/10
Filed: 2008-05-15
Abstract: A denture teeth device having a wire, strand or thread, or a plurality of wires adjustably coupled to a plurality of denture teeth to form a unit. The wire may be adjustably coupled along the lingual-apical portions of the denture teeth. The wire may be flexible to permit development of a dental arch form so that the denture teeth can be readily adapted to individual patient needs.  The wire may also serve to improve denture tooth retention in a processed denture base. The wire may be adjustably coupled to the denture teeth so as to not constrain the denture teeth along the length of the wire, allowing for customized arrangement of the denture teeth, including the incorporation of denture tooth overlaps, vertical and horizontal discrepancies, diastemata and facial-lingual and mesial-distal angular variation. The apical and lingual portions of the denture teeth may be contoured to facilitate the creation of anatomically realistic and hygienically favorable papilla forms and occlusion or the patient's bite.
Patent CA-2705403-A1 (CA)
Title: Method of managing a set of virtual environment control entities, device, and corresponding computer program product
Inventor: PARE LOUIS
IPC: G06F9/50
Filed: 2008-12-05
Abstract: The invention relates to a method of managing a set of entities each controlling a virtual environment in which user representations evolve. According to the invention, such a method comprises the following steps: monitoring of at least one characteristic of each of said entities and/or at least one characteristic of a corresponding virtual environment; proposal to transfer and/or transfer of at least one of said user representations from a first virtual environment to a second virtual environment, as a function of the said characteristic or characteristics monitored.
Patent CA-2705643-A1 (CA)
Inventor: DAWSON MATTHEW A
IPC: E21B43/22
Filed: 2010-05-26
Abstract: Described are methods of distributing a viscosity reducing solvent to a set of wells terminating in an underground oil reservoir where the variation in the net solvent injection rate is minimized. The net solvent injection rate is the difference between the total solvent injection rate and the total solvent production rate from the set of wells, for example on an instantaneous or daily rate basis. Minimizing this variation can reduce costs associated with surface solvent storage, subsurface solvent storage, and solvent supply, since solvent supply often is least expensive when supplied at near a fixed rate. One option is to operate well pairs and to inject solvent into one well of the pair while producing oil and solvent from the other well of the pair. These methods are particularly useful in solvent-dominated, cyclic or non-cyclic, viscous oil recovery processes.
Patent CA-2707156-A1 (CA)
Title: Protein aggregation prediction systems
Inventor: DOBSON CHRISTOPHER
IPC: G06F19/22
Filed: 2008-11-13
Abstract: This invention relates to methods for identifying aggregation-prone regions in structured (folded) proteins and to related methods for determining the aggregation propensity of a protein, to computer program code and equipment for implementing the methods, and to related methods of identifying new drugs and drug targets as well as protein toxicities. A method of identifying one or more regions in the amino acid sequence of a protein which, in the folded protein, are predicted to promote aggregation, the method comprising: determining, for amino acid positions (i) along said sequence, a local propensity for aggregation (A i) at a said amino acid position, said local propensity for aggregation being determined by a combination of a hydrophobicity value, an .alpha.-helix propensity value, a .beta.-sheet propensity value, a charge value and a pattern value for said amino acid position; determining local structural stability values for said amino acid positions, a said local structural stability value comprising a measure of local structural stability at a said amino position; and combining said determined local propensities for aggregation at said amino acid positions and said local structural stability values at said amino acid positions to identify one or more regions in said amino acid sequence which, in said folded protein, are predicted to promote aggregation.
Patent CA-2710910-A1 (CA)
Inventor: HANIFL PAUL
IPC: E03D9/00
Filed: 2010-07-22
Abstract: A trapping device for trapping non-dispersing cloths in a toilet bowl is disclosed. The trapping device comprises a strap, a plurality of hooks, and an adjustment buckle. The trapping device may be installed in a trapway of the toilet bowl. The strap has a first end, a second end, and a middle portion, wherein the second end includes a plurality of adjustment holes, and the middle portion is rounded. The plurality of hooks is attached to an inner wall of the strap, wherein the hooks extend at approximately 45-60 degrees away from the strap. The adjustment buckle is attached to the first end of the strap, wherein the second end of the strap slides through the adjustment buckle to adjust the diameter of the strap.
Patent CA-2712584-A1 (CA)
Inventor: PAULEN THOMAS GIJSBERT
IPC: B65D77/28
Filed: 2009-01-16
Abstract: A pouring package for a liquid comprises an at least substantially liquid-tight container (10) with an outflow opening (15) in a wall surface (11) thereof. At the position of the opening (15) a pouring member (30) is arranged with an outlet (33) on a distal outer end thereof at which a liquid can exit the product space. In a closed position the pouring member extends at least substantially flat against the wall surface. At least a distal outer end of the pouring member can be erected into a ready- to-use position.
Patent CA-2713220-A1 (CA)
Inventor: BOUCHE NICOLAS
IPC: A61B17/42
Filed: 2009-02-13
Abstract: A recoverable intra-uterine system comprises a receptacle (10) designed to contain one or more elements chosen from the group comprising an embryo, male and/or female gametes, a fertilized oocyte, an unfertilized ovum, and a combination of these elements, and a retaining device (20) for retaining the recoverable intra-uterine system in the uterus. The retaining device (20) comprises a deformable element (21) designed to be retained by bearing in the neck of the uterus. Use in artificial insemination techniques.
Patent CA-2714045-A1 (CA)
Inventor: HOERDUM ELO LAU
IPC: A61M5/158
Filed: 2009-02-06
Abstract: The invention relates to an assembly comprising - an insert-er (10) for insertion of a penetrating member (7) into a patient, - a pene-trating member attached to the inserter (10) before use, - a base part com-prises a position shaped to receive the penetrating member where the pene-trating member can be attached to the base part during use and fastening means (2) which can provide for the base part to be attached to the patient, where the inserter (10) comprises inserter attachment means (14) locking the inserter (10) to the base part before and during insertion of the pene-trating member (7) which inserter attachment means can be unlocked so that the inserted can be removed from the base part after insertion of the penetrating member (7), the inserter attachment means comprise at least one protruding part and at least one corresponding opening. Either the at least one protruding part or the at least one corresponding opening part is positioned on a surface of the base part and a corresponding part either comprising a protruding part or an opening is positioned on a surface of the inserter.
Patent CA-2714819-A1 (CA)
Inventor: LIN CHANG-CHEN
IPC: A47C1/024
Filed: 2010-09-13
Abstract: A leisure rocking chair includes a seat, a backrest, a fixed seat, a rocking base and a rocking mechanism. The fixed base includes a horizontal beam on an upper portion thereof. The rocking mechanism includes front and rear rocking rods and a connecting rod. The front and i-ear rocking rods, the horizontal beam, and the connecting rod are pivotably connected. A fixed support is mounted to the connecting rod. The rocking base is fixed to the fixed support. A positioning plate is mounted to the fixed base and includes a plurality of positioning holes. The rocking mechanism includes an adjusting seat adjacent to the positioning plate. An adjusting lever is mounted to the adjusting seat and includes a tail portion extendible into one of the plurality of positioning holes to fix the rocking mechanism. The adjusting lever includes a control arm on a head portion thereof.
Patent CA-2715159-A1 (CA)
Inventor: ABURANO TAMIO
IPC: G01T1/161
Filed: 2009-01-15
Abstract: A cerebral blood flow rate quantification device (10) comprises: a nuclear medicine image acquisition unit (12) for acquiring a nuclear medicine image of the head of a subject administered with a radiopharmaceutical; a count calculation unit (16) for calculating the number of counts obtained from a unit region indicating the same location in brain tissue in a plurality of nuclear medicine images of the head successively imaged between first time and second time; a cerebral blood flow rate calculation unit (24) for calculating, for each unit region, the value of a cerebral blood flow rate that makes the value of a function integrated from the first time to the second time equal to the number of counts, the function which, with cerebral blood flow rate and time elapsed from the administration of the radiopharmaceutical being as variables, expresses the concentration of the radiopharmaceutical in brain tissue; and a cerebral blood flow map generation unit (30) for generating a map showing cerebral blood flow based on the cerebral blood flow rate in each unit region. Consequently, the cerebral blood flow rate can be accurately quantified even at a relatively early stage after administration of a radiopharmaceutical.
Patent CA-2718070-A1 (CA)
Inventor: ECCLESTONE TIMOTHY JOHN
IPC: H01Q25/00
Filed: 2009-02-27
Abstract: An antenna feed assembly (15) is provided which includes at least two elongate feed chains (1, 2) lying adjacent one another. Each feed chain is adapted to transmit or receive electromagnetic radiation between itself and the antenna (34) along a longitudinal feed axis (3, 4) thereof via a transmit/receive element (7).  The feed chains (1, 2) are held in fixed lateral relationship to one another by first and second mountings (5, 6) spaced apart axially of the feed chains. The transmit/receive elements (7, 8) extend axially from the first mounting (5) towards the antenna and the second mounting (6) is positioned on a side of the first mounting (5) remote from the antenna. The first mounting (5) has a lower coefficient of thermal expansion in the lateral direction than the second mounting (6) whereby translational movement of each transmit/receive element (7, 8) in the lateral direction owing to temperature change of the assembly (15) will be reduced.
Patent CA-2718562-A1 (CA)
Inventor: DOWNS JEREMIAH
IPC: B32B7/00
Filed: 2009-02-02
Abstract: A device for deterring behavior of pets which is a laminate of a reflective plastic layer having a thickness of about 0.5 to 10.0 mils and capable of making a sound when the sheet is flexed, a fibrous layer, and a decorative fabric layer, where the layers are joined together to form the device.
Patent CA-2719953-A1 (CA)
Inventor: MCAREE PETER ROSS
IPC: E02F3/43
Filed: 2009-03-31
Abstract: The present invention relates generally to the field of positioning mechanical equipment, and particularly to the likes of mechanical excavation and electric mining shovels. In one embodiment, there is disclosed a system for calibrating the sensors that measure hoist and crowd motions for an electric mining shovel, enabling the position of a bucket to be known with greater accuracy than can be achieved using previously known approaches.
Patent CA-2720531-A1 (CA)
Inventor: SCHRIMPF MICHAEL R
IPC: A61K31/166
Filed: 2009-03-27
Abstract: The invention relates to novel amide derivatives that are positive allosteric modulators of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.
Patent CA-2722189-A1 (CA)
Inventor: COPENHAVER GREGORY P
IPC: C12P1/04
Filed: 2009-04-21
Abstract: The present disclosure relates generally to methods for processing a feedstock. Specifically, methods are provided for processing a feedstock by mixing the feedstock with an additive organism that comprises one or more transgenes coding for one or more enzymes. The expressed enzymes may be capable of breaking down cellulosic and lignocellulosic materials and converting them to a biofuel.
Patent CA-2726774-A1 (CA)
Inventor: WU MARGARET M
IPC: C10L1/16
Filed: 2009-03-24
Abstract: Disclosed is a hydrocarbon blend made from 0.001 to 10 wt% of at least one poly-.alpha.- olefin, by weight of the blend, the at least one poly-a-olefin having a Kv100 within the range of from 10 to 3000 cSt and a molecular weight distribution within the range of from 1.0 to 4.5; and a base stock having a Kv100 below 20.0 cSt; wherein the at least one poly-.alpha.-olefin is present in an amount sufficient to lower the pour point of the blend by at least 5°C relative to the pour point of the base stock. The blend is formed by (a) reacting a catalyst composition and a feed containing at least two sets of .alpha.-olefins, wherein the first set of .alpha.-olefins is selected from C4 to C12 .alpha.-olefins and the second set of .alpha.-olefins is selected from C14 or larger .alpha.-olefins. The .alpha.-olefin feed may have a number average carbon number of at least 8 carbon atoms or greater.
Patent CA-2727413-A1 (CA)
Inventor: EHBING HUBERT
IPC: H01L31/042
Filed: 2009-06-03
Abstract: The solar module according to the invention consists of a transparent adhesive layer (1), in which the solar cells (3) that are interconnected by cell connectors (2) are embedded. A  transparent, UV stable, thin front layer (4), composed for example of a thin pane of glass, is located above said adhesive layer. The supporting sandwich element (5), consisting of a nucleic layer (6) and glass fibre layers (7) bonded by means of polyurethane is located on the rear face. Fastening elements (8) and an electric socket (9) are integrated into the supporting sandwich element. A barrier film (10), which prevents the entry of water and oxygen, adjoins the sandwich element. The solar module has peripheral edge protection (11) consisting of elastomeric polyurethane, which prevents the lateral penetration of water, dirt and oxygen. The invention also relates to a method for producing the solar module.
Patent CA-2728661-A1 (CA)
Title: Main seal system and method for use in an electronic device
Inventor: GARCIA JORGE L
IPC: H05K5/06
Filed: 2009-08-20
Abstract: A main sealing sys-tem (500) for use in an electronic de-vice comprises a first half housing (501) and a second half housing (516) such that a sympathetic seal (525) is attached integrally with the first half housing (501). The second half housing (516) comprises an inte-grally formed compression surface (511) for biasing the sympathetic seal (525) in an outwardly manner to pre-vent fluid from entering a cavity (618) formed when the first half housing (501) and second half hous-ing (516) are joined to form an en-closure for the electronic device.
Patent CA-2728701-A1 (CA)
Inventor: DUCHATELLE THIERRY FRANCOIS MAURICE
IPC: F02C7/20
Filed: 2009-05-14
Abstract: Turbomachine structural casing (52), such as an intermediate casing (52) or an exhaust casing (81, 87), formed of elements comprising at least two, one internal (60) and one external (62), coaxial shell rings and radial arms connecting the shell rings (60, 62), characterized in that at least one of these elements is formed of several parts bolted together. Said parts can be made of different materials. The invention applies to structural casings having a diameter of more than 110 cm.
Patent CA-2729000-A1 (CA)
Title: Blood transcriptional signature of mycobacterium tuberculosis infection
Inventor: BANCHEREAU JACQUES F
IPC: C12Q1/00
Filed: 2009-06-25
Abstract: The present invention includes methods, systems and kits for distinguishing between active and latent mycobac-terium tuberculosis infection in a patient suspected of being infected with mycobacterium tuberculosis, and distinguishing such patients from uninfected individuals, the method including the steps of obtaining a gene expression dataset from a whole blood obtained sample from the patient and determining the differential expression of one or more transcriptional gene expression mod-ules that distinguish between infected and non-infected patients, wherein the dataset demonstrates an aggregate change in the lev-els of polynucleotides in the one or more transcriptional gene expression modules as compared to matched non- infected patients, thereby distinguishing between active and latent mycobacterium tuberculosis infection.
Patent CA-2729722-A1 (CA)
Inventor: SEEHOFF GARY STANLEY
IPC: A47G29/00
Filed: 2011-01-27
Abstract: A bed riser storage device including at least one holder portion. The bed riser storage device connects with a bed riser. A system with a bed riser storage device including at least one holder portion, and a bed riser removably connected to a bed leg.
Patent CA-2730688-A1 (CA)
Title: Gasification apparatus with continuous solids discharge
Inventor: HANROTT CHRISTOPH
IPC: C10J3/52
Filed: 2009-07-11
Abstract: The invention relates to a process for the discharge of slag and ash from a gasification reactor in which these solids are directed from the gasification reactor into a water bath housed with the gasification reactor in a pressure vessel. There are at least two lock hoppers underneath the water bath which are fed with a stream of water/solids via a pipe and a flow divider element, it being possible to supply the lock hoppers individually and in a controlled manner with a stream of water/solids via shut-off devices. The filling is performed in a manner that encourages the settling process by withdrawing a stream of liquid from the lock hopper being filled, the filling time being controlled so as to prevent the solids settling above the valves and lock hoppers The invention also relates to an apparatus with at least two lock hoppers underneath the water bath of a gasification reactor, there being, in an advantageous embodiment, a flow divider element and shut-off devices between the water bath and the lock hoppers.
Patent CA-2730939-A1 (CA)
Inventor: CARROLL JOSEPH
IPC: F03D5/00
Filed: 2009-07-17
Abstract: A power generation system (20) including an airborne electricity generator (30), a tether assembly (40) configured to carry electricity from the generator to land, the tether assembly having a first end portion (42) coupled to the generator, and a winch assembly (50) configured to reel the tether assembly onto a drum (52),wherein the winch assembly is configured to apply a reel tension to the tether assembly reeled onto the drum that is lower than a tension in the first end portion of the tether assembly.
Patent CA-2732948-A1 (CA)
Title: Utilisation d'une forme soluble d'hla-g dans le traitement des proliferations anormales des lymphocytes b
Inventor: ROUAS-FREISS NATHALIE
IPC: A61P35/02
Filed: 2009-07-31
Abstract: Nouvelle utilisation des formes solubles d'HLA-G, dans le traitement ou la prévention des proliférations anormales des cellules B telles que les cancers liquides de type B.