baber/WOPTO huggingface dataset:
Patent EP-2950784-A2 (EP)
Inventor: HAYES MARK E
IPC: A61K9/127
Filed: 2014-02-03
Abstract: The present invention provides liposome compositions containing sparingly soluble drugs that are used to treat life-threatening diseases. A preferred method of encapsulating a drug inside a liposome is by remote or active loading. Remote loading of a drug into liposomes containing a transmembrane electrochemical gradient is initiated by co-mixing a liposome suspension with a solution of drug, whereby the neutral form of the compound freely enters the liposome and becomes electrostatically charged thereby preventing the reverse transfer out of the liposome. There is a continuous build-up of compound within the liposome interior until the electrochemical gradient is dissipated or all the drug is encapsulated in the liposome. However, this process as described in the literature has been limited to drugs that are freely soluble in aqueous solution or solubilized as a water-soluble complex. This invention describes compositions and methods for remote loading drugs with low water solubility (< 2 mg/mL). In the preferred embodiment the drug in the solubilizing agent is mixed with the liposomes in aqueous suspension so that the concentration of solubilizing agent is lowered to below its capacity to completely solubilize the drug. This results in the drug precipitating but remote loading capability is retained. The process is scalable and, in liposomes in which the lipid composition and remote loading agent are optimized, the resulting drug-loaded liposomes are characterized by a high drug-to-lipid ratios and prolonged drug retention when the liposome encapsulated drug is administered to a subject.
Patent EP-3025381-A2 (EP)
Inventor: MASSONNET NICOLAS
IPC: H01L35/24
Filed: 2014-07-15
Abstract: The invention relates to a method for manufacturing a thermoelectric module comprising a substrate and at least one conductive or semi-conductive polymer film deposited on a surface of the substrate, which method comprises a step (12) of manufacturing the conductive polymer film independently of the surface of the substrate and the transfer (14) of the conductive polymer film to the surface of the substrate. The transfer (14) comprises: immersing (26) the conductive polymer film in a transfer bath so as to obtain a conductive polymer film that is solvated, self-supporting and capable of matching the shape of the surface of the substrate; applying (28) the conductive polymer film in the solvated state thereof onto the substrate such as to match the shape of the surface thereof; and drying (30) the solvated conductive polymer film.
Patent EP-2997634-A2 (EP)
Inventor: GRAY NICOLAS MCGHEE
IPC: H02H9/04
Filed: 2014-05-15
Abstract: L'invention porte sur un dispositif de suppression de tension transitoire active qui peut utiliser un réseau d'activation pour activer un commutateur à semi-conducteurs. Le réseau d'activation peut être déclenché sur la base du taux de changement de tension sur l'entrée protégée du dispositif. Plusieurs de tels dispositifs peuvent être mis en cascade en parallèle pour augmenter une dissipation d'énergie sans filtrage de dispositif et peuvent fournir une limite de tension stable sur une large plage de courants de fonctionnement. Le dispositif peut être testé pour des modes de défaillance de circuit ouvert et court-circuit dans un circuit.
Patent EP-3027619-A2 (EP)
Inventor: LIU JIAN
IPC: C07D513/04
Filed: 2014-07-28
Abstract: La présente invention concerne des composés ayant la structure de la formule (I), et des sels pharmaceutiquement acceptables desdits composés, X désignant -C(=O) ou -S(O)2-, qui sont des inhibiteurs de CETP et sont utiles pour augmenter le taux de cholestérol HDL, pour réduire le taux de cholestérol LDL, et pour traiter ou prévenir l'athérosclérose.
Patent EP-3047266-A2 (EP)
Inventor: YIN HONGFENG
IPC: G01N30/26
Filed: 2014-08-19
Abstract: A liquid chromatography (LC) column includes a wall having a length along a central axis from the inlet end to the outlet end, the wall enclosing a column interior and having a column radius relative to the central axis, the wall comprising a structured portion configured such that the column radius varies along the length; and a plurality of particles packed in the column interior, wherein at least some of the particles are in contact with the structured portion.
Patent EP-2955121-A2 (EP)
Inventor: HUIZINGH JOHN
IPC: B65G47/76
Filed: 2015-06-11
Abstract: Die vorliegende Erfindung betrifft ein Transportmittel (2), das insbesondere die Form eines flachen, kastenförmigen Behälters oder eines Tablars aufweist und dafür geeignet ist, Güter (G), insbesondere Brief- oder Paketsendungen, aufzunehmen und innerhalb eines Transport- und / oder Verteilersystems mithilfe von Förderbändern und / oder Rollenförderern befördert oder transportiert zu werden. Das Transportmittel weist einen Boden (4) auf, dessen Unterseite als Auflagefläche (4a) auf einem Untergrund dient und dessen Oberseite als Ladungsfläche (4b) für die zu transportierenden Güter dient. Kennzeichnendes Merkmal des Transportmittels ist, dass der Boden derart keil- oder rampenförmig ausgebildet ist, dass der Abstand zwischen Auflagefläche und Ladungsfläche von einer ersten Seite zur gegenüberliegenden zweite Seite hin zunimmt. Daneben betrifft die vorliegende Erfindung ein Transport- oder Verteilersystem und ein Verfahren zum Transportieren und Verteilen von Gütern.
Patent EP-2993716-A2 (EP)
Inventor: HWANG SAN
IPC: H01M50/528
Filed: 2015-08-11
Abstract: A battery includes an electrode assembly; a cap plate comprising an electrode terminal; and an electrode lead coupled to the cap plate, wherein the electrode lead electrically connect the electrode assembly and the electrode terminal, wherein a coupling location of the cap plate and the electrode lead is the center of the electrode lead. 
     An electric resistance of a charge/discharge path may be reduced and output performance may be improved
Patent EP-3116681-A2 (EP)
Title: Vorrichtung und verfahren zum messen und überwachen von werkzeugen
Inventor: KLUFT WERNER
IPC: B23Q17/09
Filed: 2015-03-13
Abstract: Bei einer Vorrichtung zum Messen und Überwachen von Werkzeugen einer Werkzeugmaschine, wobei die Werkzugmaschine eine in einem Spindelgehäuse angeordnete Spindelwelle für das Werkzeug aufweist, wobei mittels des Werkzeugs ein Werkstück mit guter elektrischer Leitfähigkeit spanabhebend bearbeitbar ist, wobei die Spindelwelle gegenüber dem Spindelgehäuse elektrisch isoliert ist, mit einem Mess- und Überwachungssystem, wobei das Mess- und Überwachungssystem mindestens eine von dem Kontaktzustand zwischen dem Werkzeug und dem Werkstück abhängige elektrische Messgröße misst, ist vorgesehen, dass ein Drehübertrager zum Messen der zwischen dem Werkzeug und dem Werkstück erfassbaren Messgröße die sich drehende Spindelwelle kontaktiert, wobei der Drehübertrager elektrisch isoliert mit dem Spindelgehäuse verbunden ist.
Patent EP-3152162-A2 (EP)
Inventor: FEYEN MATHIAS
IPC: C01B39/48
Filed: 2015-06-03
Abstract: The present invention relates to a process for the preparation of a zeolitic material having a CHA-type framework structure comprising YO 2  and X 2 O 3 , wherein said process comprises the steps of: (1) providing a mixture comprising one or more sources for YO 2 , one or more sources for X 2 O 3 , one or more tetraalkylammonium cation R 1 R 2 R 3 R 4 N + -containing compounds, and one or more tetraalkylammonium cation R 5 R 6 R 7 R 8 N + -containing compounds as structure directing agent; (2) crystallizing the mixture obtained in step (1) for obtaining a zeolitic material having a CHA-type framework structure; wherein Y is a tetravalent element and X is a trivalent element, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R 7  independently from one another stand for alkyl, and wherein R 8  stands for cycloalkyl, as well as to zeolitic materials which may be obtained according to the inventive process and to their use.
Patent EP-3169923-A2 (EP)
Inventor: BEELE JOHANNES ALFRED
IPC: F16L5/04
Filed: 2015-09-10
Abstract: L'invention concerne un système de support de câbles et/ou canalisations de diamètres différents dans un conduit comprenant une pluralité de manchons du type caoutchouc ou caoutchouteux destinés à être insérés dans un tel conduit, la pluralité de manchons comprenant un certain nombre d'unités de manchons collées qui sont orientées parallèlement les unes aux autres, les manchons présentant des dimensions externes correspondantes à l'intérieur de chaque unité, et au moins une unité comprenant un manchon présentant un diamètre interne différent d'un diamètre interne d'un manchon d'au moins une autre unité du nombre d'unités, le nombre d'unités et les dimensions des unités étant tels qu'une pile d'unités peut être réalisée avec celles-ci, chaque manchon étant également orienté parallèlement à l'un quelconque des autres manchons dans la pile d'unités, la pile d'unités présentant une forme rectangulaire dont chaque côté est formé en détail par la présence d'un certain nombre des manchons et dont chaque bord est formé en détail par la présence d'un, de deux ou trois des manchons.
Patent EP-3158310-A2 (EP)
Inventor: WITTMAN KFIR
IPC: G01M17/02
Filed: 2015-06-18
Abstract: Systems and methods are disclosed for tire management that can detect various aspects of tires and determine tire status, from tires rotating on a moving vehicle.
Patent EP-3161591-A2 (EP)
Inventor: ROSENBERG ILYA DANIEL
IPC: G06F3/041
Filed: 2015-06-25
Abstract: A tactile touch sensor (TTS) system and method allowing physical augmentation of a high-resolution touch sensor array (TSA) is disclosed. Physical augmentation is accomplished using a TSA physical overlay (TPO) placed on top of the TSA. The TPO is constructed to transmit forces to the underlying TSA. Force transmission is accomplished by either using a flexible overlay or with a rigid mechanical overlay that transmits user forces exerted on the overlay to the underlying TSA. Incorporation of TPO identifiers (TPI) within the TPO permits identification of the TPO by a TPO detector (TPD) allowing operational characteristics of the TSA to be automatically reconfigured to conform to the currently applied TPO structure by a user computing device (UCD). The UCD may be configured to automatically load an appropriate application software driver (ASD) in response to a TPI read by the TPD from the currently applied TPO.
Patent EP-3174706-A2 (EP)
Inventor: ALMS JUSTIN B
IPC: B32B5/02
Filed: 2015-07-31
Abstract: A method of making a composite article involves first forming an intermediate substrate. The intermediate substrate can be formed from fibers and an uncured thermoset polymer composition followed by partial cure, or from fibers and an uncured thermoset polymer composition followed by cure of the thermoset polymer composition and deposition of a thermoplastic on the surface of the substrate, or from fibers and an uncured thermoset polymer composition followed by cure and exposure of the substrate to organic solvent, a plasticizer, moisture, and/or heat. The intermediate substrate prepared according to any of the above techniques is then subjected to cold gas spray deposition to deposit a metal layer onto the intermediate substrate. In the case where the substrate was formed by partially curing a thermoset polymer composition, the metal-coated partially-cured thermoset polymer substrate is then fully cured.
Patent EP-3121084-A2 (EP)
Inventor: PARK SANGHA
IPC: B60W10/22
Filed: 2016-07-19
Abstract: An autonomous vehicle includes an input unit configured to receive selection input of at least one of a time mode for driving to a set destination, a fuel efficiency mode, a safety mode, or a comfort mode. The autonomous vehicle further includes a power source driver configured to control an engine comprising a supercharger or a turbocharger or both and a controller configured to control the power source driver to turn the supercharger or the turbocharger on or off according to the selected mode.
Patent EP-3142108-A2 (EP)
Inventor: BAKSHI DHRUV
IPC: G06F17/27
Filed: 2016-08-23
Abstract: Methods, apparatus, and computer-readable media (transitory and non-transitory) are provided herein for reducing latency caused by switching input modalities. In various implementations, a first input such as text input may be received at a first modality of a multimodal interface provided by an electronic device. In response to determination that the first input satisfies one or more criteria, the electronic device may preemptively establish a session between the electronic device and a query processor configured to process input received at a second modality (e.g., voice input) of the multimodal interface. In various implementations, the electronic device may receive a second input (e.g., voice input) at the second modality of the multimodal interface, initiate processing of at least a portion of the second input at the query processor within the session, and build a complete query based on output from the query processor.
Patent EP-3307319-A2 (EP)
Inventor: CHEUNG NAI-KONG V
IPC: A61P31/22
Filed: 2016-06-09
Abstract: La présente invention concerne des anticorps, des fragments de ceux-ci et des agents de liaison multispécifiques qui se lient à la protéine membranaire latente 2 (LMP2) du virus d'Epstein-Barr (EBV) présentée par les molécules de classe I du HLA, en particulier, les molécules HLA-A02. L'invention concerne également des procédés d'utilisation de ceux-ci ou des compositions les contenant pour la détection, la prévention et/ou le traitement thérapeutique de maladies caractérisées par l'expression d'un peptide LMP2 du virus d'Epstein-Barr présenté par HLA-A02, en particulier le lymphome de Burkit, le lymphome de Hodgkin et l'épithélioma du rhinopharynx.
Patent EP-3356543-A2 (EP)
Title: Système d'expression de protéines bactériennes modifiées
Inventor: GOTTESMAN MAXWELL
IPC: C12N15/67
Filed: 2016-09-28
Abstract: La présente invention concerne des cellules hôtes pour une production fiable, à rendement élevé, de protéines recombinées, comprenant des protéines instables. La cellule hôte selon l'invention (par exemple, une cellule bactérienne) présente un déficit en au moins une protéase (ou un sous-motif d'une protéase) telle que Clp ou ClpP. Ladite cellule hôte peut également contenir un vecteur d'expression qui code pour une protéine ou un polypeptide destiné à être sur-exprimé.
Patent EP-3272600-A2 (EP)
Inventor: SADANOWICZ DAVID
IPC: B60T13/52
Filed: 2017-07-14
Abstract: A method of manufacturing vehicle brake boosters includes load testing a plurality of reaction discs and sorting the load-tested reaction discs into multiple, separate batches based on the load test results. A first batch of plunger plates is formed to an axial length to correspond with a first of the separate batches of reaction discs. A first batch of the vehicle brake boosters is assembled with a first one of the multiple, separate batches of reaction discs and the first batch of plunger plates to achieve a target jump-in force. A second batch of plunger plates is formed to an axial length to correspond with a second one of the separate batches of reaction discs. A second batch of the vehicle brake boosters is assembled with a second one of the multiple separate batches of reaction discs and the second batch of plunger plates to achieve the target jump-in force.
Patent EP-3282205-A2 (EP)
Inventor: WESSLING WILHELM
IPC: F24F13/02
Filed: 2017-08-01
Abstract: Die Erfindung betrifft eine Zuluftvorrichtung für einen Arbeitsraum, mit einem Zuluftkanal (5), der eine Außenwandung (9) aufweist und eine Einlassöffnung (7) und eine Auslassöffnung (6) bildet, wobei der Zuluftkanal (5) derart abgewinkelt ausgebildet ist, dass sich die Außenwandung (9) mit Abstand (A) zumindest teilweise über die Auslassöffnung (6) erstreckt.
Patent EP-3329987-A2 (EP)
Inventor: JOSHI VINAY K
IPC: F01N3/20
Filed: 2013-06-17
Abstract: An exhaust gas mixer 50 comprises an inner tube 52, an outer tube 53 and a plurality of blades 56. The inner tube 52 defines a central conduit. The outer tube 53 is positioned about the inner tube 52 in coaxial alignment with the inner tube 52. The plurality of blades 56 is coupled to and positioned between the inner and outer tubes 52, 53.
Patent EP-3443465-A2 (EP)
Title: Procédé, système et produit de programme en vue d'une compression, basée sur un masque, d'une matrice creuse
Inventor: HSILIN HUANG
IPC: G06F17/16
Filed: 2017-04-12
Abstract: L'invention concerne un procédé, un système et un produit de programme comprenant l'examen d'éléments d'une première matrice de manière séquentielle. Les valeurs des éléments examinés sont déterminées. Un bit correspondant d'un premier masque est fixé à une première valeur si une valeur déterminée est nulle. Un bit correspondant d'un premier masque est fixé à une seconde valeur si une valeur déterminée est non nulle. Les valeurs non nulles sont regroupées dans un premier vecteur, les bits au moins du premier masque déterminant des opérations sur des valeurs regroupées.
Patent EP-3523592-A2 (EP)
Inventor: PLOJ DEJAN
IPC: F28F3/02
Filed: 2017-10-02
Abstract: The present invention refers to a heat exchanger, in particular to a heat exchanger produced according to Roll-Bond method, comprising at least one plate made of thermally conductive material which comprises channels to enable flowing of heat-transfer medium. According to the invention, the heat exchanger is formed of a plurality of plates formed in a sense of a spiral, wherein at least one of the flat sides of the plates (1, 2) of the heat exchanger is provided with at least one means (5, 6) for improving heat transfer.
Patent EP-3396282-A2 (EP)
Inventor: OH CHANGSEOK
IPC: F25D23/02
Filed: 2018-03-29
Abstract: Refrigerator including a cabinet, a control unit provided in the cabinet and controlling an operation of the refrigerator, a main door that opens or closes the cabinet and has an opening formed therein, a main hinge that couples the cabinet to the main door and allows the main door to be pivotably mounted, a sub-door that is formed on a front surface of the refrigerator and opens or closes the opening, a sub-hinge that couples the main door to the sub-door and allows the sub-door to be pivotably mounted, a sub-hinge cover that simultaneously shield a main hinge shaft of the main hinge and a sub-hinge shaft of the sub-hinge, and a wire disposed to extend from an inside of the sub-door, to be connected with the control unit, and to sequentially pass through the sub-hinge shaft and the main hinge shaft along an inside of the sub-hinge cover.
Patent EP-3425396-A2 (EP)
Inventor: COONEY CHRISTOPHER G
IPC: B01L3/00
Filed: 2012-04-13
Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using reliable films and methods for detecting microarray spots using an internal control flurophore in the array spot.
Patent EP-3548131-A2 (EP)
Inventor: KIM DANIEL H
IPC: A61M25/09
Filed: 2018-07-27
Abstract: A medical device includes at least one ionic electroactive polymer actuator, the actuator including at least one polymer electrolyte member defining at least a surface and a plurality of electrodes disposed about the surface of the at least one polymer electrolyte member, an elongate, flexible portion defining a proximal end and a distal end secured adjacent to the ionic electroactive polymer actuator and the elongate, flexible portion further comprising a core and a sleeve surrounding the core and a plurality of electrically-conductive wires, each having a proximal end and a distal end coupled to at least one of the plurality of electrodes, wherein the at least one polymer electrolyte member deforms asymmetrically in response to the application of an electrical potential supplied through at least one of the plurality of electrically-conductive wires to at least one of the plurality of electrodes.
Patent EP-3707156-A2 (EP)
Inventor: MONIA BRETT P
IPC: C07K14/535
Filed: 2018-11-07
Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
Patent EP-3584795-A2 (EP)
Inventor: ATHANAS MICHAEL J
IPC: G16C20/70
Filed: 2019-06-07
Abstract: A method for analyzing a multidimensional data set includes generating a multidimensional mass spectrometry data set from a sample; and generating an matrix representing the multidimensional mass spectrometry data set such that a first dimension and a second dimension of the multidimensional mass spectrometry data set correspond to a matrix cell location, and an ion intensity corresponds to a matrix cell value; and determining a class of the matrix from a plurality of matrix classes using a trained neural network matrix classifier.
Patent EP-3653174-A2 (EP)
Title: Metatarsophalangeal joint replacement device and methods
Inventor: MIMNAUGH KIMBERLY
IPC: A61F2/42
Filed: 2019-08-29
Abstract: A device for the repair of a phalangeal joint comprises a first anchor, a second anchor, and a flexible spacer connecting the first and second anchors. The flexible spacer comprises a plurality of elongate fibers extending axially or criss-crossed between the first and second anchors and a polymeric matrix interspersed with the plurality of elongate fibers. Specifically, a prosthetic metatarsophalangeal joint device comprises a porous metallic metatarsal bone anchor, a porous metallic phalangeal bone anchor, and a polymeric spacer element comprising parallel or criss-crossed elongate fibers that can connect the metatarsal bone anchor and the phalangeal bone anchor. Methods for manufacturing prosthetic joint devices comprise using three-dimensional printing processes or molding processes. Methods for implanting prosthetic joint devices comprise positioning porous metallic anchor components adjacent resected bones at planar interfaces and between which a polymeric spacer having axial aligned elongate fibers embedded in a matrix can be disposed.
Patent EP-3797081-A2 (EP)
Inventor: HAID JOSEF A
IPC: B65G65/00
Filed: 2019-05-22
Abstract: Cargo receptacle comprising: i. a mount (2), ii. a flexible member (4) expandable and collapsible in height, comprising: a. a first end interconnected (5) to the mount, wherein the flexible member (4) in an at least partially expanded state bounds a storage volume for holding the cargo, and b. an external access (7) to the cargo, wherein the mount (2) is self-supporting and comprises a frame (3) with a rim (3c), said rim (3c) being suitable for mounting the cargo receptacle (1) on a system of laterally spaced-apart tracks.
Patent EP-3877872-A2 (EP)
Inventor: GARREC PATRICK
IPC: G06J1/00
Filed: 2019-11-08
Abstract: The device transforms an analog input signal with N components  x (0),  x (1)...  x (N-1) into an output signal with N components X(0), X(1)... X(N-1) functions of said components  x (0),  x (1)...  x (N-1), said device comprising basic addition and/or subtraction cells linked in a butterfly-type architecture to perform said functions, each basic cell comprising an operator performing a conditional division by two of the result of the addition (31) operation or subtraction operation performed, the condition being the saturation (33) of said operator.
Patent EP-3683840-A2 (EP)
Title: Display apparatus
Inventor: FUKASAWA TAKAYUKI
IPC: H01L27/32
Filed: 2020-01-08
Abstract: A display apparatus includes a substrate comprising a first pixel region and a second pixel region adjacent to the first pixel region; a circuit device layer on the substrate; a first light-emitting device module on the circuit device layer, the first light-emitting device module comprising a first light-emitting device overlapping the first pixel region to display a first color; and a second light-emitting device module on the first light-emitting device module, the second light-emitting device module having a first pixel penetration hole overlapping the first pixel region, the second light-emitting device module further comprising a second light-emitting device overlapping the second pixel region to display a second color different from the first color.