baber/WOPTO huggingface dataset:
Patent WO-2021055452-A1 (WO)
Title: Granular metering system
Inventor: BULLIVANT KENNETH
IPC: B01F33/40
Filed: 2020-09-16
Abstract: An additive feeder assembly includes a supply reservoir having an outlet and an outlet tube having a first end in fluid communication with the outlet and a second end located vertically higher than the supply reservoir. An air stream transports a first granular material discharged from the supply reservoir and into the first end of the outlet tube to the second end of the outlet tube. A granular material distributor is in fluid communication with the second end of the outlet tube. The granular material distributor has a top end configured for attachment to a feed supply for a second granular material, a central portion located vertically below the top end and configured to mix the first granular material and the second granular material, and a bottom end configured for vertically discharging the mixed first granular material and second granular material.
Patent WO-2021055671-A1 (WO)
Title: Knee instruments
Inventor: GOBLE E MARLOWE
IPC: A61B17/17
Filed: 2020-09-18
Abstract: Instrument systems for knee arthroplasty provide multiple bone pin holes and/or saw slots for making femoral and tibial resections. The systems are directly or indirectly positioned and oriented with respect to the femoral mechanical axis, distal surface of a femoral condyle, Whiteside's line, proximal tibial plateau, and the tibial mechanical axis.
Patent WO-2021061781-A1 (WO)
Title: Multi-task adapter neural networks
Inventor: TAGLIASACCHI MARCO
IPC: G10L15/00
Filed: 2020-09-23
Abstract: A system including a multi-task adapter neural network for performing multiple machine learning tasks is described. The adapter neural network is configured to receive a shared input for the machine learning tasks, and process the shared input to generate, for each of the machine learning tasks, a respective predicted output. The adapter neural network includes (i) a shared encoder configured to receive the shared input and to process the shared input to extract shared feature representations for the machine learning tasks, and (ii) multiple task-adapter encoders, each of the task-adapter encoders being associated with a respective machine learning task in the machine learning tasks and configured to: receive the shared input, receive the shared feature representations from the shared encoder, and process the shared input and the shared feature representations to generate the respective predicted output for the respective machine learning task.
Patent WO-2021080991-A1 (WO)
Inventor: WILSON JAMES M
IPC: C07K14/005
Filed: 2020-10-20
Abstract: L'invention concerne de nouveaux capsides d'AAV et des rAAV les comprenant. Dans un mode de réalisation, des vecteurs utilisant un capside d'AAV selon l'invention présentent une transduction accrue dans un tissu sélectionné par comparaison avec un AAV de l'état de la technique. Des capsides AAV3B issus de génie sont utiles pour générer des vecteurs rAAV pour l'administration d'un produit génique.
Patent WO-2021081478-A1 (WO)
Title: Methods for reducing electrode gap distances in electronic devices and resulting devices having nanometer electrode gaps via liquid phase molecular layer deposition technique
Inventor: TABIB-AZAR MASSOOD
IPC: B01L3/00
Filed: 2020-10-26
Abstract: A method for reducing electrode gap distances in an electronic device having a first electrode spatially separated from a second electrode by an electrode gap can comprise selecting (810) a nanometer gap size to bind a biological material based on a size of the biological material and binding effects with the biological material. The method can further comprise coating (820) at least one surface of an electrode gap region with a first layer including molecular recognition groups, and coating (830) the at least one surface with a second layer including electrically-conductive solids that are configured to bond with the molecular recognition groups. The electronic device can be further coated (840) with additional alternating layers of the molecular recognition groups and the electrically- conductive solids to reach the nanometer gap size between a first electrode and a second electrode of the electronic device.
Patent WO-2021097419-A1 (WO)
Title: Systems and methods producing seeded grafts
Inventor: BREUER CHRISTOPHER
IPC: A61L27/24
Filed: 2020-11-16
Abstract: Closed disposable seeding systems with improved seeding chambers permitting uniform seeding of a scaffold or graft with patient's cells are provided. The seeding chambers with a variable width along the length of the chamber, or a minimal gap between the scaffold and chamber wall, provide an improvement of the prior seeding chambers of closed disposable seeding systems by providing faster and more efficient and uniform seeding of the grafts and scaffolds. Also described are scaffolds with biomechanical and structural properties permitting spontaneous reversal of stenosis and neotissue formation as the graft degrades yielding a scaffold-free neovessel.
Patent WO-2021108683-A1 (WO)
Inventor: PITZEN JENNIFER
IPC: C07D403/04
Filed: 2020-11-25
Abstract: The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.
Patent WO-2021126824-A1 (WO)
Inventor: NAGEL CHRISTOPHER
IPC: B82Y30/00
Filed: 2020-12-15
Abstract: L'invention comprend un appareil et des procédés pour l'instanciation et l'impression quantique de matériaux, tels que des métaux élémentaires, dans une poudre de carbone nanoporeuse.
Patent WO-2022076010-A1 (WO)
Title: Dispositifs médicaux destinés à être utilisés en vue de la création d'un pneumopéritoine temporaire
Inventor: FOLEY GLENN
IPC: A61B17/02
Filed: 2020-12-15
Abstract: L'invention concerne des exemples de dispositifs médicaux qui comprennent un dôme rigide et un canal torique. Le dôme rigide a une géométrie hémisphérique avec un côté ouvert pour entourer un site chirurgical. Le dôme rigide a une géométrie concave pour être relié au site chirurgical, un orifice de vide de dôme pour fournir une communication fluidique pour une source de vide afin de réduire une pression à l'intérieur du dôme rigide, une ouverture pour fournir un accès au site chirurgical, et un septum pour former une barrière pénétrable au niveau de l'ouverture pour accéder au site chirurgical. Le canal torique est couplé au dôme rigide pour s'étendre le long d'une périphérie du dôme rigide. Le canal torique présente une géométrie toroïdale partielle formant un anneau autour du dôme rigide. Le canal torique comprend un orifice de vide de canal pour fournir une communication fluidique pour une source de vide afin de réduire une pression à l'intérieur du canal torique.
Patent WO-2021158299-A1 (WO)
Title: Bi-directional buffer with circuit protection time synchronization
Inventor: FISHER APRIL E
IPC: H04L7/00
Filed: 2020-12-16
Abstract: Examples described herein are used in timing synchronization systems. A timing synchronization system provides circuits that support bi-directional half-duplex voltage signals (transmit or receive) but protect against incorrect input/output configuration whereby a transmit signal media is connected to a receive port or a receive signal media is connected to a transmit port. The system provides configurable signal propagation by use of parallel connection of two or more buffer in series with a resistor. Various isolation circuitry and resistors can be used to protect against signal transmission during receive mode.
Patent WO-2021046581-A1 (WO)
Title: Systems, apparatus, and methods of conveyor belt processing
Inventor: SHLAIMOUN ZIA
IPC: B65G43/00
Filed: 2020-09-04
Abstract: A reconfigurable hardware platform uses, in place of a portion of software, a chain of reconfigurable hardware Operator Blocks to manipulate data as the data moves down the chain. This conveyor belt architecture, or chain of Operator Blocks, moves data from Operator Block to Operator Block. This conveyor belt architecture processor may be combined with a conventional front-end processor to process complex information or critical loops in hardware while processing a rest of a program as software.
Patent WO-2021146627-A1 (WO)
Title: Safety switches for regulation of gene expression
Inventor: CLARKE RYAN
IPC: C12N15/79
Filed: 2021-01-15
Abstract: Disclosed herein are cells including pluripotent stem cells that conditionally express an immunosuppressive factor and related methods of their use and generation. In some embodiments, the cells disclosed do not express MHC I and MHC II human leukocyte antigens, and in some cases, also do not express one or more TCR complexes. In some embodiments, hypoimmunogenicity of the cells is controlled by activation of a controllable expression system upon contacting the cells with a specific factor or agent.
Patent WO-2021150851-A1 (WO)
Inventor: SPENCE MATTHEW
IPC: H01M4/56
Filed: 2021-01-22
Abstract: L'invention concerne une batterie au plomb-acide. La batterie au plomb-acide comprend une électrode en fibre de carbone ayant une grille avec une bande d'alliage métallique. Dans certains exemples, la bande d'alliage métallique est un alliage de plomb. En variante, la bande d'alliage métallique est un alliage comprenant un ou plusieurs éléments parmi le plomb, le calcium, l'antimoine et l'étain. Dans certains exemples, la bande d'alliage métallique comprend également un ou plusieurs éléments parmi le cuivre, l'arsenic et le sélénium.
Patent WO-2021194629-A1 (WO)
Inventor: CALUGARU VLAD RADU
IPC: H02J3/00
Filed: 2021-01-29
Abstract: An electronic device includes an AI power controller that predicts future load transients within a system and that dynamically alters power settings in anticipation of the predicted future load transients. To predict load transients, the AI power controller receives as an input application signature data from an application executing on the device. The application signature data includes at least media frame data generated by the application during a time interval. The AI power controller executes logic to compare the received application signature data to historical application signature data, where the historical application signature data includes media frame data generated by the application during one or more past execution instances of the application. Based on the comparison, the AI power controller predicts a load transient of the application at a future point in time and dynamically adjusts a power control setting of the device in anticipation of the predicted load transient.
Patent WO-2021155372-A1 (WO)
Title: Gel pigging improvement
Inventor: MAURIER RON
IPC: G01M3/02
Filed: 2021-02-01
Abstract: A method for performing ultrasonic inspection to a pipe is described, comprising: introducing an in-line inspection tool assembly into a pipe, wherein the in-line inspection tool assembly comprises a gel reservoir and an ultrasonic inspection tool flanked by a pair of batching pigs, wherein the gel reservoir holds a first gel couplant; and driving the in-line inspection tool assembly along the pipe while performing ultrasonic inspection; wherein a gel slug is formed between the pair of batching pigs, and the gel slug facilitates the ultrasonic inspection.
Patent WO-2021247103-A1 (WO)
Inventor: MITTAL MILLIND
IPC: G06F13/40
Filed: 2021-02-18
Abstract: Embodiments herein describe techniques for separating data transmitted between I/O functions in an integrated component and a host into separate data paths. In one embodiment, data packets are transmitted using a direct data path that bypasses a switch in the integrated component. In contrast, configuration packets (e.g., hot-swap, hot-add, hot-remove data, some types of descriptors, etc.) are transmitted to the switch which then forwards the configuration packets to their destination. The direct path for the data packets does not rely on switch connectivity (and its accompanying latency) to transport bandwidth sensitive traffic between the host and the I/O functions, and instead avoids (e.g., bypasses) the bandwidth, resource, store/forward, and latency properties of the switch. Meanwhile, the software compatibility attributes, such as hot plug attributes (which are not latency or bandwidth sensitive), continue to be supported by using the switch to provide a configuration data path.
Patent WO-2021178253-A1 (WO)
Title: Anticorps anti-cd19 et leurs méthodes d'utilisation et de préparation
Inventor: CHATTERJEE SOUMILI
IPC: A61K31/165
Filed: 2021-02-27
Abstract: L'invention concerne un anticorps monoclonal isolé (mAb) ou son fragment de liaison à l'antigène ayant une spécificité de liaison à CD19 humain, le mAb isolé ou le fragment de liaison à l'antigène comprenant une séquence d'acides aminés ayant une identité avec une séquence choisie parmi SEQ ID NO. 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 91, ou 93, l'identité n'étant pas inférieure à au moins 95 %.
Patent WO-2021183389-A1 (WO)
Title: Endoscopic snare device
Inventor: USPENSKI ALEX
IPC: A61B17/00
Filed: 2021-03-05
Abstract: A tissue removal tool includes a body, a conduit, a loop, and a transmitting assembly. The conduit is attached to the body and defines an inner lumen, where the inner lumen has a proximal portion having a first width and a distal portion having a second width that is greater than the first width. The loop is movable between an open position in which the loop is at least partially disposed outside of the conduit and a closed position in which the loop is disposed within the conduit. The transmitting assembly includes a handle and a link. The handle is connected to the body, and the link has a first end attached to the handle and a second end attached to the loop such that movement of the handle causes the loop to move between the open and closed positions.
Patent WO-2021221816-A1 (WO)
Inventor: BARTER THOMAS HAMISH
IPC: H01S5/068
Filed: 2021-03-19
Abstract: A display system comprises a current source, pulse circuitry, a pulsed laser, control circuitry, and a display surface. The pulse circuitry outputs a first pulse of electrical current based upon electrical current emitted by the current source. The pulsed laser emits first light based upon the first pulse, wherein luminance of the first light is based upon a first amplitude of the first pulse. The control circuitry generates an estimate of pulse history effects on second light that is to be emitted by the pulsed laser, the estimate is generated based upon a parameter of the first pulse and a desired luminance of the second light. The control circuitry causes the pulse circuitry to output a second pulse of electrical current based upon the estimate. Based upon the second pulse, the pulsed laser emits second light with the desired luminance.
Patent WO-2021188955-A1 (WO)
Title: Leveraging actual cable network usage
Inventor: MACAULEY WILLIAM
IPC: H04W72/00
Filed: 2021-03-19
Abstract: Determining a bit rate at which to deliver a packet stream over a network link. An origin device transmits over the network link unsolicited data packets to a destination device while contemporaneously transmitting over the network link a first packet stream encoded at an initial bit rate to the destination device. The origin device may be, but need not be, a content delivery network (CDN) edge node and the destination device may be, but need not be, a cable modem (CM). The origin device determines whether the network link supports delivering a second packet stream in lieu of the first packet stream encoded at a higher bit rate based, at least in part, on an amount of retransmission requests the origin device receives for packets in the first packet stream from the destination device.
Patent WO-2021202349-A1 (WO)
Title: Substituted silanes as chain transfer agents for polyolefin production
Inventor: KRASOVSKIY ARKADY
IPC: C08F4/34
Filed: 2021-03-29
Abstract: Embodiments are directed to a method of making an olefin-based polymer by free-radical polymerization in a reactor system. The method includes initiating a free-radical polymerization of an olefin-based monomer, propagating growth of the olefin-based polymer during continued free-radical polymerization of the olefin-based monomer, and adding to the reactor system a chain transfer agent that terminates the growth of the olefin-based polymer. The chain transfer agent includes a silane. Examples of suitable silanes are: triethylsilane, diethylmethylsilane, tris(trimethylsilyl)silane, n-butylsilane, dimethylphenylsilane, phenylsilane, chlorodimethylsilane, diisopropylaminosilane, 1,2-bis(dimethylsilyl) benzene, 1,3-bis(dimethylsilyl) benzene, 1,4-bis(dimethylsilyl)benzene, 1,1, 3,3-tetramethyldisiloxane, trimethylsilane, (trimethylsilyl)dimethylsilane, and bis(trimethylsilyl)methylsilane.
Patent WO-2021206975-A1 (WO)
Title: Medical devices for electroporation
Inventor: GRUBA SARAH
IPC: A61N1/04
Filed: 2021-03-31
Abstract: A medical device comprising a tube, a first electrode and a second electrode, and a structure at a distal portion of the tube, the structure defining a first section and a second section, wherein the first and second sections are configured to be filled with a conductive medium, wherein the first electrode is contained within the first section, and the second electrode is contained within the second section, and wherein the structure includes a central barrier separating the first section from the second section, and the central barrier is insulative.
Patent WO-2021211368-A1 (WO)
Title: Ai-assisted sound effect generation for silent video
Inventor: KRISHNAMURTHY SUDHA
IPC: H04N21/854
Filed: 2021-04-09
Abstract: Sound effect recommendations for visual input are generated by training machine learning models that learn coarse-grained and fine-grained audio-visual correlations from a reference visual, a positive audio signal, and a negative audio signal. A trained Sound Recommendation Network is configured to output an audio embedding and a visual embedding and use the audio embedding and visual embedding to compute a correlation distance between an image frame or video segment and one or more audio segments retrieved from a database. The correlation distances for the one or more audio segments in the database are sorted and one or more audio segments with the closest correlation distance from the sorted audio correlation distances are determined. The audio segment with the closest audio correlation distance is applied to the input image frame or video segment.
Patent WO-2021211416-A1 (WO)
Title: Ace2- and tmprss2-targeted compositions and methods for treating covid-19
Inventor: MADDON PAUL J
IPC: A61K39/215
Filed: 2021-04-12
Abstract: This invention provides a composition comprising (a) a first monoclonal antibody that (i) specifically binds to the extracellular portion of human angiotensin converting enzyme 2 (hACE2), (ii) specifically inhibits binding of SARS-CoV-2 to the extracellular portion of hACE2, and (iii) does not significantly inhibit the ability of hACE2 to cleave angiotensin II and/or a synthetic MCA-based peptide; and (b) a second monoclonal antibody that (i) specifically binds to the extracellular portion of human TMPRSS2 (hTMPRSS2), and (ii) specifically inhibits the entry into hACE2+/hTMPRSS2+ human cells of a pseudovirus bearing SARS-CoV-2 S protein. This invention also provides related recombinant AAV vectors, recombinant AAV particles, compositions, prophylactic and therapeutic methods, and kits.
Patent WO-2021222077-A1 (WO)
Inventor: REN ZHIFENG
IPC: C01B3/02
Filed: 2021-04-26
Abstract: An aspect of the present disclosure provides time and energy-efficient synthesis of catalysts for water electrolysis. An exemplary synthesis method includes dissolving amounts of Fe(NO 3 ) 3 ·9H 2 O and Na 2 S 2 O 3 ·5H 2 O in deionized water at ambient temperature to form a solution, placing Ni foam into the solution where the Ni foam serves as a substrate and a Ni source for growth of sulfur-doped (Ni,Fe)OOH (S-(Ni,Fe)OOH) catalysts, leaving the Ni foam in the solution at ambient temperature for a duration between one minute and five minutes to provide a treated foam where the S-(Ni,Fe)OOH catalysts grow on the substrate during the duration, and removing the treated foam from the solution after the duration.
Patent WO-2021222259-A1 (WO)
Inventor: DUTILLEUL THOMAS
IPC: B23K15/00
Filed: 2021-04-27
Abstract: The present invention provides a modification to the EBW process, which is referred to as a slope-out methodology, the results in the formation of a "slope-out portion" located generally in that region of the overall weldment located at the end of the ordinary EBW welding process for joining two components. The slope-out portion overlaps with the initial weld of the workpiece for a given distance or length along the weld and effectively eliminates the keyhole and provides a weldment that has minimal to no defects, particularly in the slope-out portion. The slope-out methodology begins by adjusting various parameters related to the electron beam to essentially decay the beam. In general, the focus position of the electron beam is moved from under-focused (focal position in the bulk of the material) to over-focused (focal position ahead of the workpiece surface) as the overlapping weld is made.
Patent WO-2022231579-A1 (WO)
Title: Garniture expansible avec élément d'étanchéité activable
Inventor: HOLDERMAN LUKE WILLIAM
IPC: E21B33/127
Filed: 2021-04-28
Abstract: L'invention concerne une garniture expansible comprenant un élément d'étanchéité activable, susceptible d'être situé dans un trou de sonde présentant une paroi et d'être activé à l'aide d'un fluide réactif. L'élément d'étanchéité comprend un métal pouvant gonfler, capable de réagir avec le fluide réactif pour former un métal gonflé et un élément mécanique séparant le fluide réactif du métal pouvant gonfler et manœuvrable pour amener le fluide réactif au contact du métal pouvant gonfler de telle façon que le métal pouvant gonfler se dilate jusqu'à interagir de façon étanche avec la paroi. Un procédé de formation d'un joint dans un trou de sonde comportant une paroi comprend les étapes consistant à situer une garniture expansible comportant un élément d'étanchéité activable à l'intérieur du trou de sonde, à utiliser un élément mécanique de l'élément d'étanchéité activable pour amener un fluide réactif au contact d'un métal pouvant gonfler, et à dilater le métal pouvant gonfler pour qu'il interagisse de façon étanche avec la paroi en faisant réagir le métal pouvant gonfler avec le fluide réactif.
Patent WO-2022231627-A1 (WO)
Title: Methods for titrating mitapivat for use in treating thalassemia
Inventor: BARBIER ANN
IPC: A61K31/4709
Filed: 2021-04-30
Abstract: Provided herein are safe and effective dosing regimens for mitapivat and pharmaceutically acceptable salts thereof.
Patent WO-2021236343-A1 (WO)
Inventor: LUO JIAN
IPC: C03C3/062
Filed: 2021-05-06
Abstract: Composition de verre présentant une teneur en SiO 2  qui est supérieure ou égale à environ 44,0 % en moles et inférieure ou égale à environ 60,0 % en moles et une teneur en ZnO qui est inférieure ou égale à environ 1,0 % en moles. De plus, la composition de verre est essentiellement exempte de Pb et de Bi. La composition de verre présente également un indice de réfraction qui est supérieur ou égal à 1,75 et une densité qui est inférieure ou égale à environ 4,5 g/cm 3 .