baber/WOPTO huggingface dataset:
Patent NZ-594370-A (NZ)
Title: Carba-nucleoside analogs for antiviral treatment
Inventor: CHO AESOP
IPC: A61K31/7064
Filed: 2010-02-09
Abstract: 594370 Disclosed is a tetrahydrofuran substituted fused pyrimidine heterocycle of formula (I) where the substituents are as disclosed in the specification. Preferably the fused ring is thieno[3,4-d]pyrimidine. Also disclosed are pharmaceutical combinations comprising a compound of formula (I), the use of a compound of formula (I) in the manufacture of a medicament and a method of treating a non-human mammal by administering a compound of formula (I). The medicament is useful in the treatment of a viral infection caused by a Flaviviridae virus. Preferably the virus is selected from the group consisting of dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis virus, St. Louis encephalitis virus, Omsk hemorrhagic fever virus, bovine viral diarrhoea virus, Zika virus and Hepatitis C virus.
Patent NZ-603376-A (NZ)
Title: Smooth muscle cell constructs
Inventor: BERTRAM TIMOTHY A
IPC: A61L27/38
Filed: 2011-05-03
Abstract: Disclosed is an implantable cell-scaffold construct for treating gastrointestinal disorders, shaped to conform to a part of a gastrointestinal organ of a subject, and comprising a population of smooth muscle cells derived from adipose or peripheral blood tissues.
Patent NZ-605404-A (NZ)
Title: Method of producing recombinant high molecular weight vwf in cell culture
Inventor: MUNDT WOLFGANG
IPC: A61K38/36
Filed: 2011-07-08
Abstract: Discloses a method of producing a recombinant Von Willebrand Factor (rVWF) composition, the method comprising; (a) providing a basal cell culture media; (b) supplementing the basal cell culture media with copper to provide a final copper concentration of at least 2.4 l.Lg/L; (c) providing one or more cells comprising a nucleic acid encoding a rVWF protein; (d) culturing the one or more cells in the cell culture media supplemented with copper such that rVWF is expressed and excreted from the cells into a culture supernatant and the NH4 + content of the culture supernatant is maintained at a concentration below 4 mM or 10 mM; and (e) recovering at least a portion of the culture supernatant, wherein the supernatant recovered has a rVWF specific ristocetin cofactor activity of at least 30 mU/l.Lg rVWF
Patent NZ-616574-A (NZ)
Title: A catalyst precursor and a process for preparation thereof
Inventor: SANDEE ALBERTUS JACOBUS
IPC: C10G2/00
Filed: 2011-04-28
Abstract: The disclosure relates to a process for preparing a catalyst precursor, which process includes forming a slurry of particles of an insoluble inorganic metal salt, particles and/or one or more bodies of a pre-shaped catalyst support in a carrier liquid, and a soluble metal salt dissolved in the carrier liquid, wherein the metals of the insoluble inorganic metal salt and the soluble metal salt are the same, and where the said metal is an active catalyst component, with the particles of the insoluble inorganic metal salt thus being contacted with the particles and/or the one or more bodies of the pre-shaped catalyst support and with the pre-shaped catalyst support thus being contacted at least once with the soluble metal salt, thereby to produce a treated catalyst support; and removing carrier liquid from the slurry to obtain a dried, treated catalyst support, which either directly constitutes the catalyst precursor, or is optionally calcined to obtain the catalyst precursor. The pre-shaped catalyst support may be aluminium oxide, silica, titania, zirconia, magnesia, zinc oxide, activated carbon, molecular sieves or zeolites. The metal of the insoluble inorganic metal salt and the soluble metal salt is selected from the group consisting of cobalt, nickel, manganese, iron, copper, ruthenium, molybdenum or zinc. The disclosure also relates to a process for preparing a catalyst and a synthesis process using the catalyst.
Patent NZ-623927-A (NZ)
Title: Dispenser
Inventor: DUIGNAN CATHAL
IPC: A61M15/00
Filed: 2012-10-31
Abstract: A dispenser for dispensing a dose of a gaseous, gas borne or droplet substance from a substance source (C), the dispenser comprising: a body for receiving a substance source, the body having a mouthpiece; a junction member slideably arranged in the body for movement in a longitudinal axis of the body to release a dose of a substance from a substance source, the junction member comprising a socket for receiving a spout of a substance source; a dispenser driver (A) for moving the junction member in the longitudinal axis of the body to release a dose of a substance from a substance source, the dispenser driver comprising a pivot shaft and a cam arranged on the shaft, the dispenser driver being arranged within the body such that rotation of the pivot shaft causes the cam to rotate and apply a force to the junction member so as to move the junction member in the longitudinal axis; and a cam follower slideably arranged within the body, the cam follower comprising a base and a substantially rigid protrusion extending from the base, the protrusion being arranged between the dispenser driver and the junction member such that a force applied by the cam of the dispenser driver to the protrusion causes the cam follower to slideably move in the longitudinal axis of the body and apply a force to the junction member so as to release a dose of a substance from a substance source.
Patent NZ-700688-A (NZ)
Title: Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
Inventor: HEARTLEIN MICHAEL
IPC: C07H21/02
Filed: 2010-11-30
Abstract: Disclosed is the use of an mRNA molecule encoding an enzyme and encapsulated within a liposome in the manufacture of a medicament for treating a subject suffering from or susceptible to a urea cycle disorder, wherein said enzyme is selected from ornithine transcarbamylase (OTC), carbamyl phosphate synthetase (CPS), argininosuccinate synthetase 1 (ASS 1), argininosuccinate lyase (ASL) or arginase (ARG).
Patent NZ-704146-A (NZ)
Title: Barbed sutures having contoured barbs that facilitate passage through tissue and increase holding strength
Inventor: NAWROCKI JESSE G
IPC: A61B17/06
Filed: 2013-09-16
Abstract: A wound closure device (200) includes a filamentary element (202) having a proximal end (206) and a distal end (210), and a plurality of barbs (204) extending outwardly from the filamentary element. Each barb has a base (230) connected with the filamentary element, a tip (232) spaced from the base, and an outer edge (234) that extends between the base and the tip. The outer edge includes a first section (242) having a concave surface that extends between the base and a transition point (246) of the barb and a second section (244) having a convex surface that extends between the transition point of the barb and the tip of the barb. The outer edge transforms from the concave surface of the first section to the convex curve of the second section at the transition point of the barb. The tip of the barb has a convexly curved surface facing the distal end of the filamentary element. The unique dual radius shape of the outer edge of the barbs and the tips of the barbs minimizes resistance when the filamentary element is pulled in a first direction through tissue and maximizes resistance to movement when the filamentary element is pulled in an opposite, second direction through tissue for holding the wound closure device stationary.
Patent NZ-706541-A (NZ)
Title: Compositions and methods for immunotherapy
Inventor: KLOSS CHRISTOPHER C
IPC: C12N15/85
Filed: 2013-10-02
Abstract: The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen recognizing receptor and one of a chimeric costimulatory receptor. Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
Patent NZ-718820-A (NZ)
Title: Stain repellent and voc eliminating coatings and use thereof
Inventor: MARTIN DARRAN L
IPC: C09D7/63
Filed: 2014-09-30
Abstract: A coating dispersion or building article can include titanium dioxide, and a dihydrazide. The coating dispersion or building article can further include calcium carbonate, calcined aluminum silicate, acrylic polymers, and a fluoroalkyl polymer. The dihydrazide is an agent capable of trapping formaldehyde and the coating dispersion or building article can protect against undesirable emissions of formaldehyde and provide stain repellency.
Patent NZ-718880-A (NZ)
Title: Operation of a hvac system using a combined hydronic and forced air system
Inventor: MACPHERSON MURDOCH
IPC: F25B49/02
Filed: 2013-07-05
Abstract: A method for heating a building is provided that can use a heated floor or slab to more efficiently heat an airflow for heating the building. An air flow can be created in an air duct and the air flow can be heated by an air conditioning system or furnace. The heated air flow can then pass through a heat exchanger connected to a radiant heating loop running through a floor or slab with a liquid circulating through them. When the airflow is being heated by the furnace, the air flow will alter the temperature of the liquid circulating through the heat exchanger and therefore the temperature of the slab. When the temperature of the slab varies from the temperature of the building, liquid that has been circulated through the radiant heating loop can be used to alter the temperature of the air flow passing through the heat exchanger.
Patent NZ-721267-A (NZ)
Title: Method for detecting staphylococcus contained in milk
Inventor: MAEHANA KOJI
IPC: G01N33/569
Filed: 2014-12-17
Abstract: The present invention addresses the problem of providing a bacteriolysis method for detecting whether or not Staphylococci are causing mastitis using the milk of livestock, and a detection method and detection kit comprising a lysis solution and an immunochromatographic device. Provided is a bacteriolysis method for Staphylococci that includes a step for lysing Staphylococci present in milk by mixing, in milk obtained from livestock, a lytic agent containing lytic enzymes and at least one amphoteric surfactant, and, preferably, at least one non-ionic surfactant. The lytic enzymes are preferably lysostaphin.
Patent NZ-732982-A (NZ)
Title: Lawn mower
Inventor: WANG ZHEN
IPC: A01D34/00
Filed: 2015-12-29
Abstract: The invention discloses a power tool and a lawn mower with battery packs. Prior to this invention, there was not much flexibility regarding how the battery packs can be charged or used. In accordance to one embodiment of the invention, each of the battery packs is individually detachable for use by other power tools; and at least one cover is connected to the power housing for covering, and allowing access to, the battery packs. This allows a user to detach the battery packs individually and charge each of the battery packs individually, or use one or more of the battery packs to supply power to other power tools.
Patent NZ-754570-A (NZ)
Title: Panels
Inventor: MILLARD SIMON
IPC: E06B5/16
Filed: 2017-11-10
Abstract: A composite panel, for example formed as door (10), comprising a first fascia (11) and a second fascia (15) at least one of which is formed from metal structural sheet material, located between the first and second fascia (11,15) are a first structural foam layer (12), a metal core layer (13) and a second structural foam layer (14), the metal core layer (13) being as thin or thinner than the first fascia (11) and/or as thick or thicker than the second fascia (15). The inventive concept is that the metal core layer is fusion bonded to the first and/or second structural foam layer. This process does not require adhesives, which can take up to 24 hours to cure, thus giving the advantage of shorter manufacturing times.
Patent NZ-757707-A (NZ)
Title: Compounds and compositions for treating hematological disorders
Inventor: SAMAJDAR SUSANTA
IPC: A61K31/00
Filed: 2018-03-30
Abstract: The present invention provides methods of treating acute myeloid leukemia or myelodysplasia syndrome with Formula II, wherein the subject has a mutation in FLT-3 kinase selected from an internal tandem duplication (ITD), a mutation in D835, F691, K663, or N841, and an ITD in combination with a mutation in D835, F691, K663, or N841, or the AML or MDS is resistant to an FLT-3 kinase inhibitor.
Patent NZ-758806-A (NZ)
Title: Refrigerator
Inventor: XIA ENPIN
IPC: E05D3/18
Filed: 2018-06-29
Abstract: A refrigerator, comprising a cabinet, a door and a hinge body 11 with a positioning shaft 12 and a guiding shaft 13 on the cabinet. The door has a positioning groove 25 fitting with the positioning shaft 12 and a guiding groove 26 fitting with the guiding shaft 13. In a first position when the door is closed, side, the door is in a first state, and the door has a side wall close to the pivoting side and a front wall away from the cabinet. In the first state, the positioning groove 25 has a first position close to the side wall and the front wall, and a second position away from the side wall and the front wall compared with the first position, the guiding groove 26 has a third position 261 and a fourth position 262, and when the door is in the first state, the positioning shaft 12 is located at the second position 252, and the guiding shaft 13 is located at the fourth position 262. The guiding shaft 13 and the guiding groove 26 are provided such that when the door is opened from the first state, the door is rotated with the positioning shaft 12 as a center of rotation, the positioning shaft 12 is moved from the second position 252 to the first position 251 and the guiding shaft 13 is moved from the fourth position 262 to the third position 261 with the limitation of the guiding shaft 13 and the guiding groove 26. At this point, the door is opened at a certain angle to be in a second state, and the door is moved by a distance towards a side away from the pivoting side. A pivoting groove 255 communicating with the positioning groove 25 is further provided on the door, with one end of the pivoting groove 255 away from the positioning groove being a pivoting position. The guiding groove has a transition groove parallel to the pivoting groove. One end of the transition groove away from the third position is a rotation starting position. The guiding groove has also a rotation ending position. The guiding groove is of an arc shape between the rotation starting position and the rotation ending position. A center of the arc is a center axis of the positioning shaft when the positioning shaft is located at the pivoting position. The hinge design does not limit the opening angle of the door of an embedded refrigerator.
Patent NZ-762749-A (NZ)
Title: Activity modulator
Inventor: SHIBUYA AKIRA
IPC: A61K39/395
Filed: 2018-11-28
Abstract: The present invention relates to: an activity modulator which is a means for modulating the activity of CD300b dependent phagocytosis; and medicine for the treatment or prevention of a disease or condition in which the activity is involved. The activity modulator comprises a CD300a binding agent and modulates CD300b dependent phagocytosis signals in a macrophage. In a specific embodiment the invention is the use of a CD300a-neutralizing antibody in the manufacture of a medicament for treating or preventing ischemic diseases.
Patent PT-104816-A (PT)
Title: Método de hidrocarboxilação de alcanos c7-c10 para produção de ácidos monocarboxílicos alifáticos
Inventor: POMBEIRO ARMANDO JOSE LATOURRE
IPC: C07C51/14
Filed: 2009-11-12
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM MÉTODO DIRECTO, EFICIENTE E ESSENCIALMENTE ''VERDE'' DE HIDROCARBOXILAÇÃO, EM MEIO AQUOSO SEM SOLVENTE ÁCIDO E A BAIXAS TEMPERATURAS, DE ALCANOS C7-C10 PARA PRODUÇÃO DE ÁCIDOS MONOCARBOXÍLICOS ALIFÁTICOS COM MAIS UM ÁTOMO DE CARBONO. ESTE MÉTODO BASEIA-SE NUMA REACÇÃO SELECTIVA, SEM METAL OU PROMOVIDA POR COBRE, ENTRE UM ALCANO E O MONÓXIDO DE CARBONO E ÁGUA, EM MEIO DE ACETONITRILO AQUOSO A 50-60ºC, E NA PRESENÇA DE UM OXIDANTE PEROXODISSULFATO. OS ALCANOS CÍCLICOS, LINEARES OU RAMIFICADOS PRÓPRIOS PARA ESTA TRANSFORMAÇÃO INCLUEM O METILCICLO-HEXANO, CIS- E TRANS-1,2-DIMETILCICLO-HEXANO, CICLO-HEPTANO, CICLOOCTANO, ADAMANTANO, N-OCTANO E 3-METIL-HEXANO.
Patent PT-117637-A (PT)
Title: Tintas de rede dupla de gel coloidal para impressão 3d, componentes, métodos de produção e usos dos mesmos
Inventor: VÍTOR MANUEL ABREU GASPAR
IPC: B33Y70/00
Filed: 2021-12-15
Abstract: AS NANOPARTÍCULAS REPRESENTAM UMA DAS CLASSES MAIS PROMISSORAS DE NANOMATERIAIS, DEVIDO ÀS SUAS VARIADAS APLICAÇÕES NA ÁREA DA ENGENHARIA DE MATERIAIS OU NA ÁREA BIOMÉDICA. A PRESENTE DIVULGAÇÃO REFERE-SE À FORMULAÇÃO DE HIDROGÉIS COLOIDAIS, COMPREENDENDO MÚLTIPLOS COMPONENTES DE NANOPARTÍCULAS COM PROPRIEDADES FÍSICO-QUÍMICAS DISTINTAS, SEUS MÉTODOS DE PRODUÇÃO E USOS DOS MESMOS. TAMBÉM SE APRESENTA A FABRICAÇÃO DE CONSTRUÇÕES 3D HÍBRIDAS DE HIDROGEL-TINTA DE GEL COLOIDAL COMPREENDENDO COMBINAÇÕES DE HIDROGÉIS POLIMÉRICOS E UM GEL OU GÉIS COLOIDAIS, POSICIONADAS ESPACIALMENTE NA MATRIZ DE HIDROGÉIS POR MEIO DE IMPRESSÃO 3D.
Patent RO-87596-A (RO)
Inventor: CHUPP JOHN P
IPC: C07C213/00
Filed: 1983-03-16
Abstract: This invention pertains to processes for the preparation of nuclear substituted benzylic halides such as ortho-amino benzyl chlorides by reaction of substituted benzyl sulfoxides with nonoxidizing acid halides.
Patent RU-94001067-A (RU)
Inventor: GINKULOV G V
IPC: F03B13/12
Filed: 1994-01-10
Abstract: FIELD: generation of electric current in small and large rivers. SUBSTANCE: all parts of float propeller are made from rubberized fabric. Propeller consists of elongated inflatable chamber with longitudinal projections and recesses and have form of six-pointed star if viewed from the end; these projections are used as blades over entire length of propeller; propeller is provided with two rings pressed in recesses and embraced by three belts crosswise; if propeller is held by these belts in stream of river, it starts rotating transmitting the rotation through shaft belt to electric generator; other belt from second ring is secured on swivel-bearing at end of thick fishing rod (in large river) or on swivel-bearing on opposite bank (in small river). EFFECT: enhanced efficiency.
Patent RU-94020958-A (RU)
Inventor: CHAJKA V K
IPC: A61B17/42
Filed: 1994-06-03
Abstract: FIELD: medicine, obstetrics, gynecology. SUBSTANCE: hymenal opening is created by keeping hymen at the same time. So, haemotocolpos puncture is conducted. Then an opening formed is bluntly broadened with pincers by holding branches separated for 1-5 minutes. After independent secretion of collected blood vagina sanitation is conducted and sterile fatty gauze tampon is inserted into hymenal opening. Tampon should be changed for 3-5 days. EFFECT: method enables to solve the problem of obtaining normal hymenal anatomy in girls.
Patent RU-94023934-A (RU)
Inventor: DORNOSTUP S B
IPC: A62D1/00
Filed: 1994-06-24
Abstract: FIELD: fire-fighting equipment, particular, fire-extinguishing powder composition based on inorganic salt. SUBSTANCE: inorganic salt after grinding is additionally treated in electrostatic field of high voltage of 500-10000 V/cm. EFFECT: reduced fire-extinguishing surface concentration.
Patent RU-94027554-A (RU)
Inventor: KOMAROV A L
IPC: B21D22/10
Filed: 1994-07-20
Abstract: FIELD: metal pressure forming. SUBSTANCE: method comprising reduction of a blank by elastic medium onto a rigid punch, also includes steps of providing a wave of excess material on the blank before a final forming operation in such a way, that to create the excess material wave in zones of bending and (or) in places of possible loss of stability. EFFECT: enhanced quality of formed thin-wall parts, formed by such method. 2 cl, 2 dwg
Patent RU-94027813-A (RU)
Inventor: JUDIN R A
IPC: F27B17/00
Filed: 1994-07-25
Abstract: FIELD: methods of low-oxidation and nonoxidation heating of metals; engineering works and metallurgical works. SUBSTANCE: method consists in radiation heating of metal from surface of radiation tubes and convective heating with controllable atmosphere also heated from radiation tubes. Immediately after loading port, metal is heated by jets of incomplete combustion products escaping from radiation tubes; waste products of incomplete combustion and controllable atmosphere are discharged simultaneously from working space of furnace. Nonoxidation heating surface is provided with loading port, gas seal, controllable atmosphere supply and discharge pipe lines, radiation tubes located horizontally over entire length of furnace between hearth and arch; radiation tubes are provided with built-in burners and smoke discharge branch pipes. Immediately after loading port, radiation tubes are provided with holes directed towards metal being heated and have no smoke branch pipes performing the function of gas seal; they are provided with additional fuel burning chamber located outside working space of furnace. EFFECT: avoidance of oxidation of metal, high productivity and enhanced efficiency.
Patent RU-94031081-A (RU)
Inventor: ARFANITSKIJ S V
IPC: H01F38/08
Filed: 1994-08-24
Abstract: FIELD: electrical engineering. SUBSTANCE: welding transformer has a magnetic core with primary and secondary windings, and one or two yokes carry auxiliary adjusting disc windings, which can be turned and moved relative to the end faces of the main windings, envelop the yokes throughout the entire length so that their turns are parallel to the yoke longitudinal axes and hinge-joined to the magnetic core at the yoke end faces. EFFECT: fine and coarse control of welding current within a wide range, improved mass and dimensional characteristics and reduced cost of welding transformer.
Patent RU-94034745-A (RU)
Inventor: DAMBAEV G TS
IPC: A61L27/06
Filed: 1994-09-09
Abstract: FIELD: medicine, in particular, surgery, methods of surgical treatment of gastric ulcer. SUBSTANCE: resection of the lesser curvature of the stomach is conducted after its mobilization, which is started 3 to 5 cm off from the pylorus, keeping intact the end anthralic branches of the vagus; vessels and branches accompanying them are separated and cut directly at the wall of the stomach, first in the anterior and then posterior layers of the lesser omentum, gradually advancing to the stomach, first in the anterior and then posterior layers of the lesser omentum, gradually advancing to the cardial section; the wound of the stomach is sutured in longitudinal direction; the strand of the greater omentum is put on the formed sutures, which is fixed to the wall of the stomach by agraffes made of titanium nickelide, the latters are sutured by separate sutures to the posterior surface of the abdominal cavity and the remaining layers of the lesser omentum. EFFECT: reduced postoperative complications due to preservation of the anthralic branches of the vagus at mobilization of the lesser curvature of the stomach, as well as due to reduction of traumatism of operation.
Patent RU-94035831-A (RU)
Inventor: MINASJAN M A
IPC: F16F7/14
Filed: 1994-09-26
Abstract: FIELD: mechanical engineering. SUBSTANCE: vibration insulation support consists of torus-like flexible member made up as a spirally wound steel rope made up as two discontinuous parts, which are the same in length, and top and bottom supporting planks-disks. One part is made up as a rope having a right twisting. The second part has a left twisting. Turns of the rope is fixed between the planks- disks. The pitch of the turns of the flexible member is equal to a value at which a space between the inner adjacent semi-turns of the torus over periphery is preferably no less than one millimeter when the vibration insulation support is under a nominal loading. EFFECT: enhanced vibration insulation. 2 cl, 5 dwg
Patent RU-94040687-A (RU)
Inventor: ZALIVADNYJ B S
IPC: A23L1/00
Filed: 1994-11-01
Abstract: FIELD: food industry. SUBSTANCE: food "Limk" contains mixture of cocoa and/or coffee and honey with additives of these products. Licvate microadditive activated ferments of food is added. EFFECT: improved tonic properties.