baber/WOPTO huggingface dataset:
Patent WO-2023283552-A1 (WO)
Inventor: HAN SI-PING
IPC: C07H21/02
Filed: 2022-07-05
Abstract: L'invention concerne des procédés, des systèmes et des compositions pour mettre en place des acides nucléiques bloqués (LNA) dans des brins de petits ARN interférents (ARNsi), par exemple des brins de capteurs d'ARNsi activables de manière conditionnelle, ainsi que des complexes d'ARNsi générés à l'aide du procédé décrit dans la description et des brins constituants. Le complexe d'ARNsi peut être activé de manière conditionnelle lors d'une liaison complémentaire à un brin d'acide nucléique d'entrée (par exemple, un ARNm d'un gène de biomarqueur spécifique à une cellule cible) par l'intermédiaire d'une séquence dans un brin d'acide nucléique de capteur du complexe d'acide nucléique. Le complexe d'acide nucléique activé peut libérer un duplex d'ARNi qui peut inhiber spécifiquement un ARN cible.
Patent WO-2023023560-A1 (WO)
Title: Nouvelles utilisations
Inventor: CASSINO CARA MARIE
IPC: A61P31/04
Filed: 2022-08-17
Abstract: L'invention concerne de nouvelles méthodes de traitement d'infections par Staphylococcus à l'aide d'une lysine de type PlySs2, par exemple l'exebacase, par exemple, des méthodes de traitement d'endocardite avec une lysine de type PlySs2, par exemple l'exebacase; des méthodes de traitement d'infections par Staphylococcus impliquant le système nerveux central ; des méthodes de traitement de jeunes enfants ; et des méthodes d'accélération de la résolution de symptômes d'une infection par Staphylococcus
Patent WO-2023086890-A1 (WO)
Inventor: NIHESH NAOREM
IPC: A61K31/33
Filed: 2022-11-10
Abstract: The present disclosure concerns immunomodulatory compositions and methods of use for enhancing response to an antigen (e.g., in a vaccine), an immunotherapy (e.g., a cancer immunotherapy), or other immune stimulation. The disclosure describes immunomodulators having reduced toxicity and improved immune response compared with existing adjuvants. Further disclosed are methods for improving an immune response to a vaccine antigen, cancer immunotherapeutic, or other immune stimulating agent. The disclosure describes dimeric and polymeric immunomodulators comprising one or more pattern recognition receptor (PRR) agonist moieties and one or more NF-κB inhibitor moieties.
Patent WO-2023192003-A1 (WO)
Inventor: BRENT LONNIE
IPC: A61K31/506
Filed: 2023-03-06
Abstract: Described herein are methods of treating a human patient with a newly diagnosed neuroendocrine tumor, methods of treating patients with neuroendocrine tumors with early signs of carcinoid heart disease who have not had a heart valve replacement, and methods of treating a human patient with the neuroendocrine tumor who has had a recent heart valve replacement. Administering telotristat ethyl to these patients can reduce the development of carcinoid heart disease and improve clinical outcomes.
Patent WO-2023177754-A1 (WO)
Inventor: ZHANG ZHENGMING
IPC: G01N27/48
Filed: 2023-03-15
Abstract: L'invention concerne des systèmes et des procédés d'évaluation de la stabilité électrochimique d'un matériau comprenant la fourniture d'une cellule électrochimique ayant une cellule tubulaire, un matériau d'électrolyte, et au moins une électrode de référence et au moins une électrode de travail. L'électrode de travail peut être en feuille d'aluminium et/ou de cuivre. Dans certains cas, l'électrode de travail peut être revêtue d'un matériau de test. Dans certains autres cas, le matériau d'électrolyte peut être prétraité avec un matériau de test. La cellule électrochimique peut être soumise en partie à une procédure de voltampérométrie cyclique pour déterminer des attributs physiques et/ou chimiques du matériau de test.
Patent WO-2023230277-A1 (WO)
Title: Systèmes et procédés de gaine vasculaire télescopique
Inventor: MACDONALD SUMAIRA
IPC: A61M25/06
Filed: 2023-05-25
Abstract: Sont divulgués ici divers modes de réalisation et des procédés associés d'une gaine vasculaire télescopique. La gaine vasculaire télescopique peut comprendre une pluralité de segments de gaine ayant chacun une section distale effilée et une section proximale. Chaque section distale effilée peut comprendre une surface d'ouverture distale et chaque section proximale peut comprendre une surface proximale externe. Chaque segment de gaine de la pluralité de segments de gaine peut être mis en prise en coulissement avec au moins un segment de gaine adjacent le long d'une ou plusieurs des surfaces d'ouverture distales et de la surface proximale externe. La gaine vasculaire télescopique peut également comprendre un passage de travail s'étendant à travers la pluralité de segments de gaine et le long d'un axe longitudinal de la gaine vasculaire télescopique. Le passage de travail peut fournir un accès à une lumière interne du vaisseau. Selon certains modes de réalisation, est divulgué un système de flux sanguin.
Patent WO-2024006126-A1 (WO)
Title: Data-based soft sensing for chemical reactor to estimate variables and detect abnormalities
Inventor: BOTRE CHIRANJIVI
IPC: G05B23/02
Filed: 2023-06-21
Abstract: A system for producing a chemical product includes a reaction zone and an information processing device, where the reaction zone is under a plurality of monitored conditions and is configured to produce the product from reactants using a chemical process characterized by a plurality of variables, and where the information processing device includes a computer processor configured to estimate the variables from the monitored conditions and detect one or more abnormalities in the variables. A method for producing a chemical product includes implementing a chemical process for producing the product from the reactants in a reaction zone under a plurality of monitored conditions, where the chemical process is characterized by a plurality of variables; estimating the variables from the monitored conditions with an information processing device; and detecting one or more abnormalities in the variables with the information processing device.
Patent WO-2024010769-A1 (WO)
Inventor: COSTA MARQUES ESTAVAM LUIZ DEL NERO
IPC: B65D25/28
Filed: 2023-07-03
Abstract: An extension device for a refuse container includes a pair of Y-shaped sides, each having a top end and a pair of spaced apart bottom ends. Two bumpers are positioned between the spaced apart bottom ends, and a device handle is positioned between the top ends of each side. A refuse handle capture assembly is positioned between the sides of the device and includes a pair of circular arms that are rotated by a central rod to transition between a locked and an unlocked position. Each of the arms include an opening for receiving and engaging the handle of a refuse container. When secured onto a refuse container, the bumpers engage the lid and back wall of the container and the device handle is positioned diagonally outward from the container to provide an adjustable mechanical advantage for allowing a user to tilt and move the refuse container.
Patent WO-2023141370-A1 (WO)
Title: Optimizing total core requirements for virtualized systems
Inventor: BARABELL ARTHUR J
IPC: G06F9/455
Filed: 2023-01-09
Abstract: A method comprises determining a respective occupancy parameter for a set of threads, each occupancy parameter indicative of a respective core occupancy for the respective thread. The method comprises determining a target core count for the set of threads and a target headroom for the set of threads. The method comprises generating a set of thread assignment orders for the set of threads. The method comprises determining a final thread assignment for the set of threads from the set of thread assignment orders based on the target core count for the set of threads and the target headroom parameter for the set of threads, wherein the final thread assignment assigns each of the set of threads to a core of the set of cores for execution. The method comprises configuring a system to execute each of the threads using the respective core assigned thereto by the final thread assignment.
Patent WO-2023147392-A1 (WO)
Inventor: ISSARI BAHRAM
IPC: E04B1/19
Filed: 2023-01-25
Abstract: Les présents aspects comprennent un ensemble ayant une architecture conjointe discrétisée et segmentée. L'ensemble comprend une première structure comprenant une paroi externe et une paroi interne, la paroi externe et la paroi interne s'étendant à partir d'une base de la première structure, et définissant une rainure, et une pluralité de parois de liaison s'étendant entre la paroi externe et la paroi interne de telle sorte que la rainure est divisée en une pluralité de segments de rainure définis par la paroi externe, la paroi interne et la pluralité de parois de liaison. L'ensemble comprend en outre une seconde structure comprenant une pluralité de segments de languette qui s'étendent dans la pluralité de segments de rainure. Un premier adhésif est inséré dans la rainure, ce qui permet de lier la pluralité de segments de languette à l'intérieur de la pluralité de segments de rainure de telle sorte que les première et seconde structures sont fixées ensemble.
Patent WO-2023178244-A1 (WO)
Inventor: ZIEMER DANIEL J
IPC: B60N2/75
Filed: 2023-03-16
Abstract: L'invention concerne des systèmes et des procédés pour un ensemble accoudoir pour un siège installé à l'intérieur d'une cabine d'un véhicule. L'ensemble accoudoir peut comprendre un support de retenue de couvercle (48) possédant des canaux (64A, 64B) destinés à recevoir un couvercle de bras (90) en préparation pour recouvrir un accoudoir. Le support de retenue de couvercle peut présenter une ou plusieurs saillies (76) agencées le long des canaux et configurées pour venir en prise avec le couvercle afin de fixer le couvercle à l'accoudoir.
Patent WO-2007073569-A1 (WO)
Title: Systeme de chauffage d'eau et d'air destine a des machines a laver et a des seche-linge
Inventor: SOLAR STANKO
IPC: D06F25/00
Filed: 2006-06-08
Abstract: L'invention constitue une nouvelle solution constructive dans le domaine des séche-linge et des machines à laver à circulation d'eau. L'invention permet un lavage efficace, faisant intervenir une faible consommation d'eau. Le procédé de lavage et le procédé de séchage de l'invention sont rapides et économiques. En outre, le procédé de séchage de l'invention est écologique. Les coûts de fabrication de la machine à laver de l'invention sont faibles, ainsi que les coûts destinés à adapter le système de l'invention sur une machine à laver existante. La machine à laver de l'invention est simple à utiliser et sa maintenance est facile etc. La reconstruction de la machine à laver de l'invention s'effectue comme suit: une vanne électrique (27) est placée au fond de la cuve (26) qui est reliée au filtre (29) par un tube (28). Derrière le filtre (29), se trouve l'échangeur de chaleur (31) qui est raccordé au tube (30). L'échangeur de chaleur (31) présente deux ouvertures d'entrée (eau propre et eau sale) auxquelles sont reliés les tubes (35) et (30) ; et deux ouvertures de sorties (eau propre et eau sale) auxquelles sont reliés les tubes (6) et (32). L'échangeur de chaleur (31) est relié, par le tube (32), à la pompe à eau (33). L'eau sale est aspirée dans la pompe à eau et injectée dans le tuyau souple (18) pour être évacuée dans le système des eaux usées. Pour le procédé de séchage, il est nécessaire de monter l'échangeur de chaleur conjointement au dispositif de chauffage électrique et au condensateur (7), ainsi qu'au tuyau souple (37) pour un apport d'air renouvelé.
Patent WO-2020056434-A1 (WO)
Title: Rock drill adapted nozzle
Inventor: TYRER DAVID CHARLES
IPC: E21D20/02
Filed: 2019-08-23
Abstract: The rock drill adapted filler apparatus which includes, a nozzle component having a body which includes a passage with has an inlet end and an outlet end, with the outlet end adapted to receive a filler valve connector of a hydraulically inflatable device, a reciprocating element having a forward portion which sealingly engages with the passage form the inlet end, a back portion which projects from the passage, which has an actuating formation and which is adapted to engage a fluid input hose, and a bore through the element, a valve member in the passage or the bore, a clamping element pivotally connected to the nozzle body, which is biased to a release position, in which the element does not engage the connector, which is actuatable to pivot from the release position to a clamped position, in which the element engages the connector to hold the end against the outlet end of the passage, and which engages the actuating formation and an elevating component which is adapted at one end to engage a chuck of the rock drill and to which, at an opposed end, the nozzle body is pivotally engaged, wherein the reciprocating element has a forward position in which the actuating formation does not cause the clamping element to pivot to the damping position and wherein, with an increase in fluid pressure in the passage, the reciprocating formation moves from the forward position to a back position and the actuating formation causes the clamping element to pivot to the clamping position.
Patent DK-202100005-A1 (DK)
Title: Dynamic trawl steering system
Inventor: JACK E REMØY
IPC: A01K73/04
Filed: 2021-01-04
Abstract: The present invention relates to a trawl steering system comprising a sea vessel and a trawl system, the system including a measuring unit for detecting and monitoring the position and movements of a target volume in the sea, the target volume constituted by a school, veil or haze of fish or shrimps to be caught in the trawl, and for monitoring the position of the trawl relative to said target volume. The system also comprises sampling means for sampling information including wind, current, and vessel and trawl characteristics and a route estimator for calculating an optimal trawl path and controller means for adjusting vessel and trawl parameters so as to provide a movement for the trawl toward the target volume along said optimal path and thus increase the catch and reducing the bunker consumption and associated environmental impact.
Patent DK-202200320-A1 (DK)
Title: Sensor activated fluid dispensing module
Inventor: DREW WAHLBERG ROSSKELLY
IPC: A47K5/12
Filed: 2022-04-05
Abstract: The dispensing module (55) is adapted to be arranged at least partly inside a dispenser bottle for dispensing fluid contained in the bottle and includes an object detection sensor (2), a sensor controller, an electric motor (56), a pump (57), a fluid inlet pipe, a fluid dispensing nozzle, and a battery (3). The sensor controller is adapted for receiving an in-put signal from the object detection sensor (2) and for activating the electric motor (56) when an object has been detected by the object detection sensor (2). The pump (57) is arranged to pump fluid from the fluid inlet pipe to the fluid dispensing nozzle upon rotation of the electric motor. The electric motor (56) is a brushless motor controlled by a motor controller, and a single micro controller unit (MCU) includes the motor controller and the sensor controller.
Patent PH-12014501479-A1 (PH)
Title: Knotless suture, and kit containing same
Inventor: JAE KIM YOUNG
IPC: D02J3/00
Filed: 2014-06-26
Abstract: The present invention relates to a suture which is firmly maintained and fixed to an operational site to stably sustain suturing or lifting effects for a long time. More specifically, the present invention provides a suture having a conic or pyramidal shape with a cut top, wherein a suture support comprising a communication hole penetrating the both ends is provided at one end. The suture support can have one or more portions which are cut vertically from a lower end at a lower end portion having a larger diameter between the both ends, or a part of a lower end can be removed so as to form one or more gaps formed from the end at a wall of the end portion.
Patent PH-12015000477-A1 (PH)
Title: Keypad for electronic devices
Inventor: OLIVAR DANTE
IPC: H01H13/14
Filed: 2015-11-11
Abstract: This invention relates to rubber keypads for electronic devices. Keypads are equipped with skew walls. Skew walls are rubber springs. Skew walls allow the push button to bounce up and down. The bottom portion of the push button is fitted with a conductor that comes in contact with a switch on a circuit board. Once the push button is pressed, the conductor at the bottom of the push button closes the circuit on the board and triggers an electronic signal that is then received by the receiving electronic device. Characterized in that each said push button being provided with holes disposed on said keypad along the opposing sides of the skew walls of the push button, thus resistance acting on said push button when being pushed is lesser
Patent PH-12015500031-A1 (PH)
Title: Sliding seismic isolation device
Inventor: HIDEJI NAKAMURA
IPC: F16F15/02
Filed: 2015-01-06
Abstract: Provided is a high-performance sliding seismic isolation device with a slider that realizes a contact pressure of 60 MPa. The device includes an upper shoe 1 and a lower shoe (2) having sliding surfaces 1a and 2a with curvatures, respectively; and a columnar steel slider (7) disposed between the upper shoe (1) and the lower shoe (2), the slider having an upper surface 4a and a lower surface 4b that are in contact with the upper and lower shoes, respectively, and have curvatures. The upper surface 4a and the lower surface 4b of the slider (7) have a double-woven fabric layers (5) and (6), respectively, each double-woven fabric layers containing PTFE fibers and fibers with higher tensile strength than that of the PTFE fibers, and the PTFE fibers being arranged on the sides of the sliding surfaces 1a and 2a of the upper shoe (1) and the lower shoe (2).
Patent PH-12017500494-A1 (PH)
Title: Methyl-and trifluoromethyl-substituted pyrrolopyridine modulators of rorc2 and methods of use thereof
Inventor: FLICK ANDREW CHRISTOPHER
IPC: A61P37/08
Filed: 2017-03-15
Abstract: The present invention provides methyl-and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating ROR? activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
Patent PH-12018501787-A1 (PH)
Title: Multiple dispersion generator e-vaping device
Inventor: ROSTAMI ALI A
IPC: A24F40/05
Filed: 2018-08-22
Abstract: A base (71) for an e-vaping device (60) is configured to couple with multiple cartridges (22-1 to 22-N) configured to generate separate, respective dispersions. The cartridges (22-1 to 22-N) of the electronic vaping device (60) comprising: a vaporizer assembly (300A) configured to produce a vapor, the vaporizer assembly (300A) including, a first tank (309) configured to store a pre-vapor formulation, and a heater (306) configured to heat the pre-vapor formulation and form a vapor; and an atomizer assembly (300B) configured to produce an aerosol, the atomizer assembly (300B) including, a second tank (331) configured to store a pre-aerosol formulation (332), and an atomizer (330) configured to atomize the pre-aerosol formulation (332) and form the aerosol without heat. The base (71) may include multiple connectors (33-1 to 33-N) electrically coupled to the power supply. The connectors may be configured to couple multiple dispersion generators to a power supply of the base (71). The base (71) may include control circuitry (11) configured to independently control dispersion generation by dispersion generators coupled to the base (71). The control circuitry (11) may independently control dispersion generation by the first and second cartridges based on cartridge information accessed through at least one of the first and second connectors. The control circuitry (11) may control dispersion generation by controlling power supplied to the dispersion generators.
Patent DE-102004001764-A1 (DE)
Title: Ausgleich der Reibung in einem Lenksystem eines Fahrzeuges
Inventor: YAO YIXIN
IPC: B62D5/00
Filed: 2004-01-12
Abstract: Ein Verfahren zum Betrieb eines elektronischen Lenksystems (10) in einem Fahrzeug, das Verfahren weist die folgenden Schritte auf: DOLLAR A - Festlegen eines bestimmten Lenkwertes für die Richtung von mindestens einem Vorderrad (z. B. 26a), welches mindestens eine Vorderrad (z. B. 26a) sich in einer Anordnung der Vorderräder (26a, 26b) befindet; DOLLAR A - Senden eines Signals, das dem bestimmten Lenkwert entspricht, an das System der Vorderräder (26a, 26b), das mindestens ein Motor-Stellglied (24a, 24b) aufweist; DOLLAR A - Festlegen eines Drehmoment-Regelwertes für das Motor-Stellglied (24a, 24b) durch einen Regelalgorithmus; DOLLAR A - Festlegen eines Wertes für den Reibungsausgleich; DOLLAR A - Kompensieren des bestimmten Lenkwertes, der durch mechanische Reibung beeinträchtigt ist, mit dem Wert des Reibungsausgleichs und DOLLAR A - Betätigen der Vorderräder (26a, 26b) in Abhängigkeit von dem bestimmten Lenkwert.
Patent DE-102004005635-A1 (DE)
Title: Verfahren zum Herstellen von Core-Garn
Inventor: NAEGELI ROBERT
IPC: B65H63/024
Filed: 2004-02-04
Abstract: Bei einem Verfahren zum Herstellen von Core-Garn (8), wobei ein Corefaden (6) einer Faserlunte (1) zugeführt wird, bevor die Laserlunte (1) durch Drehung verfestigt wird, soll der Corefaden (6) vor der Vereinigung mit der Faserlunte (1) insbesondere auf Bruch überwacht werden.
Patent DE-102004005944-A1 (DE)
Title: Electrical connection element for electrical component for driving combustion engine injection valve has connecting pin cross-section at connection surface with smaller curvature than envelope circle enclosing cross-section
Inventor: SCHUH CARSTEN
IPC: H01L41/047
Filed: 2004-02-06
Abstract: The device has at least one electrically conducting connection pin (41,42), at least one electrically conducting wire (49), whereby the pin has a connection surface and the pin and the wire are connected together in an electrically conducting and force-locking manner at the connection surface with the aid of a connecting arrangement (50). A cross-section of the connecting pin at the connection surface has a curvature that is less than a first curvature of an envelope circle enclosing the cross-section. Independent claims are also included for the following: (A) an electrical component (B) and the use of an electrical component for driving an injection valve for an internal combustion engine.
Patent DE-102004006191-A1 (DE)
Title: Fixing device for automobile steering mechanism has U-shaped holder formed as single deep-drawn component and attached mantle sleeve having perpendicular fixing flange
Inventor: GIERSDORF KLAUS
IPC: B62D1/16
Filed: 2004-02-06
Abstract: The fixing device has a U-shaped holder (9) with 2 side arms (16,17) and a coupling limb (8) to which one end of a mantle sleeve (1) is secured so that it extends in the opposite direction to the side arms, a fixing flange (12) provided at the other end (6) of the mantle sleeve, at right angles to the longitudinal axis of the latter. The U-shaped holder is provided as a single deep-drawn component, both the side arms and the coupling limb having a U-shaped cross-sectional profile. An independent claim for a manufacturing method for a fixing device for a steering mechanism is also included.
Patent DE-102004007309-A1 (DE)
Title: Timer clock for a household appliance without an electrical network connection has a battery compartment that can be accessed from the front of the clock, that is the outside of the appliance
Inventor: MUTTI DANIEL
IPC: F24C7/08
Filed: 2004-02-14
Abstract: Clock for control of a household appliance that does not have an electrical connection, e.g. a gas oven. The clock comprises a housing (12), a display (14), at least an operating element (18) and a control unit. The clock (10) also has a battery compartment in the housing for holding one or more batteries. When the clock is mounted in the appliance the battery compartment can be accessed from outside. The invention also relates to a corresponding household appliance without an electrical network connection.