baber/WOPTO huggingface dataset:
Patent EA-010179-B1 (EA)
Title: Biochemical synthesis of 1.4-butanediamine
Inventor: EPPELMANN KATRIN
IPC: C12N9/10
Filed: 2005-07-11
Abstract: The invention relates to a process for biochemical synthesis of 1,4-butanediamine in a microorganism having an increased level of an ornithine decarboxylase activity (increased ODC activity) as compared to the native level of the ornithine decarboxylase activity, wherein in the microorganism also an increased activity of N-acetylglutamate formation is present as compared to the native level of activity of N-acetylglutamate formation in the microorganism and wherein 1,4-butanediamine produced in the microorganism is excreted into a fermentation broth, and is recovered from the fermentation broth. The invention also relates to vectors, plasmids and hosts carrying a corresponding increased ODC activity and an increased activity of N-acetylglutamate formation.
Patent EA-012821-B1 (EA)
Title: Completion system having a sand control assembly, an inductive coupler, and a sensor proximate to the sand control assembly
Inventor: PATEL DINESH R
IPC: E21B43/10
Filed: 2007-03-29
Abstract: A completion system for use in a well includes a first completion section and a second section. The first completion section has a sand control assembly to prevent passage of particulates, a first inductive coupler portion, and a sensor positioned proximate to the sand control assembly that is electrically coupled to the first inductive coupler portion. The second section is deployable after installation of the first completion section. It includes a second inductive coupler portion to communicate with the first inductive coupler portion, to enable communication between the first completion section's sensor and another component coupled to the second section.
Patent EA-014082-B1 (EA)
Title: Polymorphs of ethyl 3-[(2-{[4-(hexyloxycarbonoylamino-iminomethyl)phenylamino]methyl}-1-methyl-1h-benzimidazole-5-carbonyl)pyridin-2-ylamino]propionate
Inventor: SIEGER PETER
IPC: A61K31/4184
Filed: 2006-06-01
Abstract: The invention relates to novel polymorphs of the active ingredient ethyl 3-[(2-{[4-(hexyloxycarbonylamino-iminomethyl)phenylamino]methyl}-1-methyl-1H-benzimidazole-5-carbonyl)pyridin-2-yl-amino]propionate, their preparation and their use as drugs.
Patent EA-016662-B1 (EA)
Title: Feeder house twist dampening system
Inventor: COERS BRUCE A
IPC: A01D41/02
Filed: 2009-09-08
Abstract: An agricultural harvester includes a feeder house drivably coupled to a power source. The feeder house has a housing frame. A faceplate is pivotally coupled to the housing frame to facilitate a pivoting of the faceplate relative to the housing frame. A hydraulic cylinder has a first end connected to the housing frame and a second end coupled to the faceplate to facilitate movement of the faceplate relative to the housing frame. The hydraulic cylinder has a plurality of hydraulic ports for facilitating movement of the operating piston of the hydraulic cylinder, with at least a first hydraulic port of the plurality of hydraulic ports being connected in fluid communication with a hydraulic power system. A first accumulator containing a compressible gas charge is connected in fluid communication with the first hydraulic port of the hydraulic cylinder.
Patent EA-016016-B1 (EA)
Title: Process and plant for the thermal treatment of fine-grained solids
Inventor: MISSALLA MICHAEL
IPC: B01J6/00
Filed: 2008-08-28
Abstract: This invention relates to a process for the chemical and/or physical treatment of fluidizable substances in a reactor (1,1'), wherein fuel and combustion air preferably are supplied to a combustion chamber (4) upstream of the reactor and burnt at a temperature of about 1000°C to about 1500°C. The hot gas is introduced into the reactor interior (2) via a central tube (3). The hot gas and the central tube (3) are cooled with a coolant. Furthermore, this invention relates to a plant for performing such process.
Patent EA-016991-B1 (EA)
Title: Packing body
Inventor: KUMASAKA YOSHINORI
IPC: B65D85/07
Filed: 2008-10-02
Abstract: A packing body suitable as a portable packing body which can change the appearance under a state where an article is contained. The packing body (1) containing an article comprises a container main body (2) for containing an article, and an extending portion (3) extending outward of the container main body (2), with the outer side face of a central region in the height direction of the container main body (2) as the proximal end (31). The packing body (1) can be changed from a first mode where the extending portion (3) is arranged to cover the side of the first end (21) of the container main body (2) from the proximal end (31) to a second mode where the extending portion (3) is arranged to cover the side of the second end (22) of the container main body (2) by reversing the extending portion (3) along the proximal end (31). An opening (33) for exposing a second end face (24) on the side of the second end (22) at least in the second mode is formed at the extension end (32) of the extending portion (3).
Patent EA-018460-B1 (EA)
Title: Pharmaceutical composition containing salt of strontium, vitamin d and cyclodextrin
Inventor: BRIAULT GILLES
IPC: A61K33/24
Filed: 2010-11-26
Abstract: A pharmaceutical composition containing a salt of strontium, vitamin D, and cyclodextrin.
Patent EA-016319-B1 (EA)
Title: Surface state of the tread of a tyre
Inventor: NARITA NOBUTAKA
IPC: B60C11/03
Filed: 2008-09-29
Abstract: The invention relates to a tread (1) for a tyre, that comprises a plurality of grooves (21, 22) defining blocks (4) and/or ribs, the grooves having an average thickness H. The tread has a rolling surface (10) intended to be in contact with the road when rolling, the rolling surface being characterised in that it is in contact with the road only by a plurality of relief contact lines (7), the relief contact lines intersecting each other in order to define a plurality of cavities on the rolling surface (10), i.e. portions located radially inside said rolling surface.
Patent EA-018396-B1 (EA)
Title: Human antibodies that bind mesothelin, and uses thereof
Inventor: TERRETT JONATHAN A
IPC: A61K39/00
Filed: 2008-09-29
Abstract: The present disclosure provides isolated monoclonal antibodies that specifically bind to mesothelin with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human mesothelin. In certain embodiments, the antibodies are capable of internalizing into mesothelin-expressing cells or are capable of mediating antigen dependent cellular cytotoxicity. The invention further provides anti-mesothelin antibodies that can inhibit the binding of mesothelin to the ovarian cancer antigen CA125. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Antibody-partner molecule conjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for detecting mesothelin, as well as methods for treating cancers, such as mesotheliomas, pancreatic cancers and ovarian cancers, using an anti-mesothelin antibody of this disclosure.
Patent EA-017703-B1 (EA)
Title: Pipe screw joint
Inventor: GOTO KUNIO
IPC: C09D7/48
Filed: 2008-12-02
Abstract: A pipe screw joint constituted of a pin and a box each having a contact surface having a threaded part and a thread-free metal contact part. A solid anticorrosive coating film which is made mainly of an ultraviolet-cured resin and is preferably transparent is formed on the contact surface of the pin. A solid lubricating coating film exhibiting a plastic or viscoplastic rheological behavior is formed on the contact surface of the box preferably from a composition comprising a thermoplastic polymer, a wax, a metal soap, a corrosion inhibitor, a water-insoluble liquid resin, and a solid lubricant by the hot-melt method.
Patent EA-019379-B1 (EA)
Title: Mounting member for measuring device and tyre having such mounting member
Inventor: EL-BERRICHI REDA
IPC: B60C23/04
Filed: 2009-09-21
Abstract: A member (12) forming a mount is provided for a measuring device (26). The mounting member for a device (26) includes a substantially flat bottom surface (16) for connection with a tyre, delimited by a contour (20), a top surface (24) for mounting the measuring device (26), delimited by a contour (30), a peripheral surface (34) forming a skirt for connecting of the contour (20) of the bottom surface (16) to the contour (30) of the top surface (24), wherein at least one of mount parameters (12): a contour curvature (30) of the top surface (24), and a profile curvature (74) of a profile of the peripheral surface (34), in a section on any plane (70) perpendicular to the bottom surface (16) and orthogonal to a tangent (72) to the contour (20) of the bottom surface (16) at a point (1) of intersection of the plane (70) with the contour (20) of the bottom surface (16), is variable and has a continuous variation along the contour (30) of the top surface and the profile (74). According to the invention a tyre is also provided comprising such mounting member (12) for a measuring device (26).
Patent EA-019660-B1 (EA)
Title: Storage tank for mold mixture in a mold forming machine with a device for supplying and discharging air
Inventor: TSUZUKI SHUICHI
IPC: B22C15/24
Filed: 2010-03-25
Abstract: The present invention is aimed at developing a machine and a method for suctioning and exhausting air from a storage tank a mold mixture in a mold forming machine, which has lesser on-off valves and prevents sticking the forming mixture to the inner part of the valve for air exhausting during the step of air exhausting. A machine for suctioning and exhausting air from a storage tank for sand in a molding machine comprising a storage tank for sand in the molding machine; a porous body that is provided in the storage tank for sand and that is distant from an inner face of the storage tank for sand; an empty chamber that is formed by an outer face of the porous body and the inner face of the storage tank for sand; a seal that is placed at a rim of a tip of a nozzle for filling sand of the storage tank for sand and that expands when compressed air is supplied inside the seal; a pilot-operated valve for both suctioning and exhausting air that is fluidly connected to the empty chamber; and an on-off valve that is fluidly connected to the pilot-operated valve for both suctioning and exhausting air and connected to an inside of the seal.
Patent EA-025825-B1 (EA)
Title: Method and system for treating a subterranean formation
Inventor: BONEY CURTIS L
IPC: C09K8/62
Filed: 2011-05-10
Abstract: A method and apparatus to treat subterranean formations comprising a wellbore including introducing a tool to a wellbore in a region of low permeability or damage, treating the region of low permeability or damage with a fluid, simultaneously measuring a fluid pressure drop and volume of fluid flow in a particular region, and moving the tool to another region. A method and apparatus to treat subterranean formations comprising a wellbore including introducing to a wellbore a tool in a region of low permeability or damage, treating the region of low permeability or damage with a fluid, introducing a diversion agent, and moving the tool to another region wherein the fluid comprises a tracer.
Patent EA-027655-B1 (EA)
Title: Method for producing a pane having an electrical connection element
Inventor: SCHLARB ANDREAS
IPC: H05B3/86
Filed: 2012-05-29
Abstract: The present invention relates to a method for producing a pane having at least one electrical connection element, wherein a) soldering compound (4) is applied to at least one contact face (8) of the connection element (3) and the soldering compound (4) has at least one recess (6) having a flux (7), b) the connection element (3) is arranged over the soldering compound (4) on a region of an electrically conductive structure (2) on a substrate (1), and c) the connection element (3) is connected to the electrically conductive structure (2) by means of the soldering compound (4) with introduction of heat.
Patent EA-030454-B1 (EA)
Title: CONJUGATE OF BIOLOGICALLY ACTIVE POLYPEPTIDE MONOMER AND IMMUNOGLOBULIN Fc FRAGMENT WITH REDUCED RECEPTOR-MEDIATED CLEARANCE, AND METHOD FOR PREPARING THE SAME
Inventor: PARK SUNG HEE
IPC: A61K39/395
Filed: 2014-07-14
Abstract: The present invention relates to a long-acting pharmaceutical composition containing a conjugate comprising a physiologically active polypeptide linked to an immunoglobulin Fc fragment, wherein the composition contains a monomeric conjugate comprising one molecule of the physiologically active polypeptide linked to a single immunoglobulin Fc fragment, and optionally contains a multimeric conjugate comprising two or more molecules of the same physiologically active polypeptide linked to a single immunoglobulin Fc fragment, provided that the molar ratio of the monomeric conjugate to the multimeric conjugate in the composition is at least 19; a physiologically active polypeptide monomer-immunoglobulin Fc fragment conjugate comprising a physiologically active polypeptide monomer linked via a non-peptidyl linker to an immunoglobulin Fc fragment, wherein the physiologically active polypeptide is linked via the non-peptidyl linker to the immunoglobulin Fc fragment in a monomeric form, wherein the conjugate demonstrates a lower receptor-mediated internalization or receptor-mediated clearance, compared either to a dimer conjugate having two molecules of a physiologically active polypeptide linked via the non-peptidyl linker to one immunoglobulin Fc fragment, or to a conjugate comprising a physiologically active polypeptide dimer linked in-frame to the immunoglobulin Fc fragment; and a method for preparing the long-acting pharmaceutical composition.
Patent EA-032799-B1 (EA)
Title: Method for preparing methyl formate
Inventor: NI YOUMING
IPC: C07C41/01
Filed: 2014-11-17
Abstract: The present application relates to a method for preparing methyl formate. A raw material containing formaldehyde, methanol and/or dimethyl ether is introduced into a first reaction zone to come into contact with a catalyst A, and a component I is obtained by separation. The component I is introduced into a second reaction zone to come into contact with a catalyst B so as to obtain, by separation, methyl formate as a product, dimethyl ether that is returned to the first reaction zone and a component II that is returned to the second reaction zone. The ratio of formaldehyde, methanol and/or dimethyl ether in the raw material is formaldehyde:methanol and/or dimethyl ether=1:2-4 in terms of the number of moles of carbon atoms contained in a corresponding component; the weight hourly space velocity of formaldehyde in the raw material is 0.01-15.0 h; the temperature is 50-100°C in the first reaction zone; the temperature is 50-200°C and the pressure is 0.1-10 MPa in the second reaction zone; and the components are independently in the gaseous phase and/or liquid phase. In the present application, the catalysts have an extended service life, reaction conditions are mild, raw material utilization rate is high, thus continuous production is allowed and large-scale industrial application potential is provided.
Patent EA-036949-B1 (EA)
Title: Biologically cleavable tetrapeptide linking agents
Inventor: CARLSON JEFFREY C
IPC: C07K5/107
Filed: 2016-05-27
Abstract: Tetrapeptide linkers for reversibly linking a first compound to a amine-containing second compound are described. Compounds containing the tetrapeptide linkers and methods of using the tetrapeptide linkers are also described.
Patent EA-036960-B1 (EA)
Title: Seal with a blockable rotor for measuring instruments
Inventor: CERBARI SERGHEI
IPC: G09F3/03
Filed: 2018-03-02
Abstract: The invention relates to means for sealing measuring instruments and equipment, specifically to seals with a blockable rotor to enable monitoring for unauthorized access to instruments measuring consumption of electrical and heating energy, natural gas and water. A seal with a rotor comprises a transparent body (1) made from a high-strength plastic and formed with a cylindrical cavity (2) having a blind end and openings (3) which are formed on lateral sides of the cavity (2) and through which a flexible sealing element passes, and a rectangular cavity (4) which is installed at the open end of the cavity (2), transversely with respect to the latter, wherein the cavities (2) and (4) are interconnected. A rotor (6) is arranged in the cavity (2) so as to be rotatable in one direction. Openings for the flexible sealing element are formed in the lateral walls of the cavity (2) and in the rotor. A cross-shaped blocking element (9) is installed at one end of the rotor. A device (5) for blocking the rotation of the rotor is arranged in the cavity (4), one end of which device is provided with two projections in the form of a fork (13), between which a trapezoidal groove (15) is formed for securing the cross-shaped blocking element (9).
Patent EA-034781-B1 (EA)
Title: Aryl, heteroaryl and heterocyclic compounds for treatment of a disorder mediated by complement factor d
Inventor: WILES JASON ALLAN
IPC: C07D471/04
Filed: 2016-08-25
Abstract: Compounds, methods of treatment and pharmaceutical compositions of inhibitors of complement Factor D comprising Formula I or a pharmaceutically acceptable salt thereof, wherein A, B, L, X, X, Q, Qand Qare as defined in the claims, are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.
Patent EA-037460-B1 (EA)
Title: NOVEL CRYSTALLINE SALT FORM OF 2,2-DIMETHYL-6-((4-((3,4,5-TRIMETHOXYPHENYL)AMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-2H-PYRIDO[3,2-b][1,4]OXAZIN-3(4H)-ONE FOR MEDICAL APPLICATION
Inventor: NOVIKOV FEDOR NIKOLAEVICH
IPC: A61P19/02
Filed: 2017-05-10
Abstract: The invention relates to the chemistry of organic compounds, to pharmacology and to medicine, and pertains to the prevention and treatment of human and animal diseases associated with metabolic disorders of bone tissues and/or cartilage tissues, particularly diseases of the musculoskeletal system, such as osteoarthritis or osteoporosis, using a novel salt form of 2,2-dimethyl-6-((4-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazin-2-yl)amino)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one. A salt of the compound with 4-methylbenzenesulfonic acidincluding the hydrates and solvates thereof, and polymorphic modifications of the salt, hydrates and solvates, is characterized by increased effectiveness of inhibiting Src-family kinases, Syk kinase and also other therapeutically-significant kinases, and by acceptable pharmacokinetic parameters. The present invention also relates to pharmaceutical compositions containing a therapeutically-effective amount of the salt according to the invention.
Patent EA-037237-B1 (EA)
Title: System and method for controlling a vehicle system to achieve different objectives during a trip
Inventor: MEYER BRIAN NEDWARD
IPC: B61L25/02
Filed: 2016-03-04
Abstract: A system (e.g., a control system) includes a sensor configured to monitor an operating condition of a vehicle system during movement of the vehicle system along a route. The system also includes a controller configured to designate one or more operational settings for the vehicle system as a function of time and/or distance along the route. The controller is configured to operate in a first operating mode responsive to the operating condition of the vehicle system being at least one of at or above a designated threshold, and in a second operating mode responsive to the operating condition of the vehicle system being below the designated threshold. The controller designates operational settings to drive the vehicle system toward achievement of a first objective when in the first operating mode and toward achievement of a different, second objective when in the second operating mode.
Patent EA-039178-B1 (EA)
Title: Tunnel profile element covering periphery of tunnel profile
Inventor: JAKOBSEN ROLF
Filed: 2018-09-10
Abstract: The invention discloses a tunnel profile element (10, 20A, 20) comprising a lightweight body constituted by foam glass panels sprayed with unbroken polyurea layer providing a fire resistant coating and increased mechanical integrity of the tunnel profile element (10, 20A, 20).
Patent ES-2180427-B1 (ES)
Title: Sistema para el control a distancia o telemetrico de expositores de carteles.
Inventor: BACKER DIRKS CHARLES
IPC: G09F13/04
Filed: 2001-04-12
Granted: 2004-04-16
Abstract: Sistema para el control a distancia o telemétrico de expositores de carteles. Este sistema está compuesto por un dispositivo electrónico de proceso (2) incluido en el expositor (1), encontrándose conectados al mismo una serie de sensores electrónicos (31, 32, 33) que le proporcionan información sobre el funcionamiento de los diferentes elementos a controlar en el expositor (1) y un dispositivo de transmisión y recepción de datos a distancia (4) que permite el intercambio de información entre el mencionado dispositivo electrónico de proceso (2) y un dispositivo de gestión exterior (5) remoto. Este sistema permite gestionar a distancia y desde el dispositivo de gestión exterior (5) diferentes expositores fijos y expositores multicartel.
Patent ES-2219141-B1 (ES)
Title: Sistema de seguridad para cabina de mando de aeronave.
Inventor: VELA MARTINEZ JUAN PEDRO
IPC: B64D45/00
Filed: 2002-02-13
Granted: 2006-01-16
Abstract: Sistema de seguridad para cabinas de mando en aeronave, que dispone, al menos de dos mamparas transversales al eje de la aeronave, disponiendo una de dichas mamparas una puerta de acceso a la zona de cabina de mando y la otra mampara una puerta de acceso a la zona de pasaje, siendo al menos la mampara y la puerta de la zona de cabina de mando resistentes a impacto de proyectil de arma de fuego. Las dos mamparas se cierran entre sí formando un prisma hermético. De aplicación en aeronaves.
Patent ES-2192149-B1 (ES)
Title: Explosor capaz de soportar la corriente de un rayo.
Inventor: MEPPELINK JAN
IPC: H01T4/16
Filed: 2002-03-15
Granted: 2004-10-16
Abstract: Para construir un explosor capaz de soportar la corriente de un rayo con varios explosores conectados en serie, en donde el explosor consta de n explosores parciales (FS) cuya tensión de cebado de arco eléctrico se ha llevado, conectando en serie los explosores parciales (FS), a n veces el valor de la tensión de cebado de arco eléctrico de un explosor parcial, y los explosores parciales (FS), con excepción del primer explosor (FS1) en reaccionar en caso de que aparezca una corriente de rayo, están conexionados por medio de condensadores de modo que los explosores parciales (FS) se hagan conductores sucesivamente, estando el segundo y cualquier explosor adicional (FS2-FSN) aplicados directamente a un potencial de referencia común a través de los condensadores, de modo que dicho explosor se encienda sólo a una sobretensión de rayo, se propone que el dimensionamiento de los condensadores se efectúe con arreglo a la fórmula siguiente: **FIGURA01**
Patent ES-2224851-B1 (ES)
Title: Emisor termoelectronico de alto rendimiento.
Inventor: FERNANDEZ GARCIA ISAAC
IPC: F24D19/10
Filed: 2003-05-12
Granted: 2006-07-16
Abstract: Emisor termoeléctrico de alto rendimiento que consiste en un cuerpo (1) provisto de dos tapones (2) y (3) dotados de reductores para el acoplamiento de un presostato (7), así como de una válvula de seguridad, disponiendo de una ventana de verificación (6) así como de un termostato (8), una tarjeta electrónica (9), un interruptor general y dos conexiones (11) y (12).