baber/WOPTO huggingface dataset:
Patent CA-3075300-A1 (CA)
Title: Compositions et methodes de soins des cheveux
Inventor: KRZYSIK DUANE
IPC: A61K8/898
Filed: 2018-08-24
Abstract: La présente invention concerne des méthodes et des compositions pour la prévention ou la réduction des frisottis. Les compositions sont anhydres et comprennent au moins un constituant fluide polysiloxane choisi parmi une amodiméthicone et un constituant polysiloxane comprenant une pluralité de chaînes latérales amines encombrées. Les compositions comprennent également un constituant transporteur liquide volatil compatible avec de la silicone, de préférence choisi parmi un constituant siloxy volatil de faible masse moléculaire ; un hydrocarbure ; et un alcool. Les compositions sont de préférence des sérums ou des fluides, et sont appropriées pour être utilisées dans un conditionneur, en tant que produit de soins des cheveux « sans rinçage », ou en tant que produit de soins des cheveux de retouche approprié pour être utilisé au cours de la journée.
Patent CA-3075532-A1 (CA)
Inventor: ROY KEVIN
IPC: C40B30/06
Filed: 2018-09-14
Abstract: The present disclosure relates to multiplex production and phenotyping of genetically engineered cells using RNA-guided nucleases and genomic barcoding. In particular, high-throughput multiplex genome editing is achieved utilizing a system that facilitates precise genome editing at desired target chromosomal loci by homology directed repair. Integration of guide RNA and donor DNA sequences as a genomic barcode at a separate chromosomal locus allows identification, isolation, and massively-parallel validation of individual variants from a pool of transformants. Strains can be arrayed according to their precise genetic modifications, as specified by donor DNA incorporation in heterologous or native genes. The present disclosure further relates to a method of editing codons outside of canonical guide RNA recognition regions, which enables complete saturation mutagenesis of protein-coding genes, a marker-based internal cloning method, which removes background due to oligonucleotide synthesis errors and incomplete vector backbone cleavage, and a method of enhancing homology directed repair by active donor recruitment.
Patent CA-3076751-A1 (CA)
Inventor: Wargacki Stephen Paul
IPC: A61K9/70
Filed: 2018-09-26
Abstract: L'invention concerne des compositions pharmaceutiques possédant des propriétés permettant une perméation améliorée du principe actif.
Patent CA-3077622-A1 (CA)
Title: Device and method for borescope inspection of jet engines
Inventor: PETERS JAN OKE
IPC: G01N21/954
Filed: 2018-10-16
Abstract: A device (1) for the borescope inspection of turbine blades (82) of the first high-pressure turbine stage (81) of a jet engine (80), comprising a kink-free guide tube (2) for guiding through a flexible borescope (70), wherein the device (1) comprises a guide (10) for the guide tube (2) for the clear and reproducible positioning and orienting the guide tube (2) and a fastening device (20) for releasably fastening the guide (10) on the outer side of the jet engine (80), wherein the fastening device (20) has an orientation unit (30), with which the guide (10) can be set to a predefined orientation with respect to the outer side of the jet engine (80), and wherein the guide tube (2) is rigid and shaped such that the end (3) of the guide tube (2) introduced into the jet engine (80) can, if the guide (10) is oriented correctly, be oriented pointing between two predefined guide blades (83). The invention further relates to a method for the inspection of turbine blades (82) of the first high-pressure turbine stage (81) of a jet engine (80) using the aforementioned device to identify the turbine blades (82), which can be seen by the borescope (70) and were previously aligned, as first turbine blades (81').
Patent CA-3078769-A1 (CA)
Title: Pyridine carbonyl derivatives and therapeutic uses thereof as trpc6 inhibitors
Inventor: BOUYSSOU THIERRY
IPC: C07D213/04
Filed: 2018-10-25
Abstract: The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R7, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Patent CA-3079918-A1 (CA)
Inventor: GILET JEAN-PHILIPPE
IPC: C09K23/42
Filed: 2018-11-08
Abstract: Method for preparing alkoxylated secondary alcohols of formula (I) where: - the group formed by Ri and R2 and the carbon atom to which Ri and R2 are attached represents 2-octyl or 4-methyl-2-pentyl, - n ranges from 1 to 100, and A represents a sequence of one or more units chosen from ethylene oxide, propylene oxide, butylene oxide and their mixtures, in which a) alcohol of formula R1CH(OH)R2 (II) is reacted, in which Ri and R2 and the carbon atom to which they are attached are as defined above, with n ethylene oxide(s) in the presence of one catalyst of the dimetallic cyanide type, and b) the product obtained in a) is reacted with one or more oxides chosen from ethylene oxide, propylene oxide, butylene oxide and their mixtures, in the presence of the catalyst of the dimetallic cyanide type. The method allows the alkoxylation of secondary alcohols in a simple manner and is applicable industrially at a low cost.
Patent CA-3080018-A1 (CA)
Inventor: LUO DAKAI
IPC: D04H3/005
Filed: 2020-05-01
Abstract: The invention discloses a fiber filament non-woven fabric with a small pore size and a large porosity, which adopts an island type ultra-fine fiber single filament, which is juxtaposed into an unidirectional silk layer several times, and a thin strip-shaped liquid is applied laterally on the unidirectional silk layer. The resin adhesive liquid bonds and fixes all the silk layers into a unidirectional non-woven fabric fixed in a grid segment. The unidirectional non-woven fabric is covered with meltblown non-woven fabric on one or both sides to make a filter material that can 100% filter viruses, bacteria, and micro-particles smaller than PM2.5. It can also be used for a wider range of filter materials, thermal insulation materials, oil absorption materials, battery separator materials, medical and health materials, environmental protection materials, clothing materials, wiping materials.
Patent CA-3085339-A1 (CA)
Title: Devices and methods for ocular surgery
Inventor: SCHALLER MICHAEL P
IPC: A61F9/007
Filed: 2018-12-14
Abstract: A surgical device for cutting a lens within a capsular bag of an eye. Related methods, systems, and devices are also provided.
Patent CA-3088776-A1 (CA)
Inventor: BORTOLUSSI CLAUDIO
IPC: A01G17/06
Filed: 2019-01-15
Abstract: La présente invention concerne un dispositif de support sur un poteau de support, en particulier pour au moins un fil destiné à retenir une rangée, le dispositif comprenant : un élément porte-fil (1 ; 101 ; 201 ; 301) constitué d'un corps de type fil façonné comprenant une partie de repos (2 ; 102 ; 202 ; 302) conçue pour reposer de manière amovible, lors de l'utilisation, sur une première partie (3 ; 103 ; 203 ; 303) de la surface extérieure du poteau de support (P1 ; P2 ; P3 ; P4) et de moyens de support (4 ; 104 ; 204 ; 304) pour le fil de retenue, s'étendant depuis des côtés opposés par rapport à la partie de repos (2 ; 102 ; 202 ; 302) ; et un élément de traction et d'ancrage (8 ; 108 ; 208 ; 308) constitué d'un corps en forme de fil façonné comprenant une partie de mise en prise (9 ; 109 ; 209 ; 309) qui est conçue pour interagir, lors de l'utilisation, avec une seconde partie (10 ; 110 ; 210 ; 310) de la surface extérieure du poteau de support (P1 ; P2 ; P3 ; P4) faisant face à la première partie (3 ; 103 ; 203 ; 303), et de moyens d'ancrage (11 ; 111 ; 211 ; 311) élastiquement déformables qui s'étendent sensiblement perpendiculairement et depuis des côtés opposés par rapport à la partie de mise en prise (9 ; 109 ; 209 ; 309) et qui sont conçus pour coopérer avec la seconde partie (10 ; 110 ; 210 ; 310) de la surface extérieure du poteau de support (P1 ; P2 ; P3 ; P4). La partie de mise en prise (9 ; 109 ; 209 ; 309) de l'élément de traction et d'ancrage (8 ; 108 ; 208 ; 308) est conçue pour venir en prise et pour appliquer, lors de l'utilisation, une force de traction sur l'élément porte-fil (1 ; 101 ; 201 ; 301) conçue pour ancrer de manière amovible l'élément porte-fil (1 ; 101 ; 201 ; 301) sur la première partie (3 ; 103 ; 203 ; 303) de la surface extérieure du poteau de support (P1 ; P2 ; P3 ; P4) par l'intermédiaire des moyens d'ancrage (11 ; 111 ; 211 ; 311) coopérant avec la seconde partie (10 ; 110 ; 210 ; 310) de la surface extérieure du poteau de support (P1 ; P2 ; P3 ; P4).
Patent CA-3089163-A1 (CA)
Title: Method for analysing a biological sample containing biological cells, and analysing device for implementing the analysing method
Inventor: ROUSSEAU ALAIN
IPC: G01N15/10
Filed: 2019-03-04
Abstract: The invention relates to a method for analysing a biological sample containing biological cells, and an analysing device for implementing the analysing method. The analysing method comprises a step of measuring cytometry parameters for each biological cell contained in a biological sample; a step of determining, for each biological cell of the biological sample, a point in space with N dimensions, the coordinates of which are defined as a function of the cytometry parameters measured for the corresponding biological cell, wherein N is an integer greater than or equal to 3; a step of automatically grouping together the points in different clusters of cells as a function of the cytometry parameters measured, so as to define a sample cluster file; and a step of comparing the sample cluster file with reference cluster files, each of the reference cluster files being defined on the basis of cytometry parameters of a respective pathological or abnormal biological sample.
Patent CA-3090234-A1 (CA)
Title: A collapsible and adjustable vessel treatment device and advanced cuff with independent and dynamically controlled charge and discharge modes for a vessel or sac wall treatment and a cardiac assist device
Inventor: WALSH PETER
IPC: A61M60/122
Filed: 2020-08-17
Abstract: The present invention provides a method of treating a vessel in a human or animal body, said method including the steps of: preparing a patient; identifying a site in said vessel requiring treatment; positioning an implantable device against a portion of tubular or sac wall of said vessel at said site. The present invention further provides a treatment device for operating with a wall of a vessel in a human or animal body, said treatment device including a changeable volume portion which is adapted for attachment to said vessel and for modifying the volume of said vessel, characterised in that the device further comprises a mechanical or electronic-mechanical energy storage device which is adapted to function with said changeable volume portion such that, in use, the changeable volume portion decreases the vessel volume when applied, allowing the volume of the vessel to increase during systole and dampen pressure by the changeable volume portion and energy storage device absorbing energy, subsequently releasing said absorbed energy during diastole to cause said changeable volume portion to decrease the vessel volume, said device having additional mechanical and electronic device and sensor components to control the load applied to the wall and device to allow electronic dynamic dampening control and mechanical or electronic-mechanical energy harvesting and discharging means. The present invention further provides a cuff for operating with a wall of a vessel in a human or animal body, said cuff is adapted for attachment to said vessel for modifying the volume of said vessel.
Patent CA-3094412-A1 (CA)
Inventor: ROMERO UGALDE HECTOR-MANUEL
IPC: A61B5/00
Filed: 2019-03-06
Abstract: The invention relates to an automated system for blood glucose level monitoring, having a processing and monitoring unit adapted to predict, from a mathematical model (501), the future trend of the blood glucose level G(t) of the patient, in which the model accepts as inputs: a variable EE(t) representative of the trend, over time, of the energy expended by the patient; a variable IOB(t) representative of the trend, over time, of the quantity of insulin taken on by the patient; and a variable COB(t) representative of the trend, over time, of the quantity of glucose taken on by the patient, and in which the mathematical model (501) is a model of the black box type, that is to say a non-physiological model defined solely by observation of the effects of the input variables EE(t), IOB(t) and COB(t) on the output variable G(t), without taking account of the various known physiological mechanisms acting within the body of the patient.
Patent CA-3096549-A1 (CA)
Inventor: GEORGIOU GEORGE
IPC: A61P35/00
Filed: 2019-04-16
Abstract: Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.
Patent CA-3097277-A1 (CA)
Title: Method and device for optically measuring distances
Inventor: HOLZHUTER HANNO
IPC: G01S7/4865
Filed: 2020-10-27
Abstract: What is proposed is a method (100) for optically measuring distances, in the case of which a first plurality of measuring pulses (13) is emitted (101) during a first measuring interval (10) by means of a transmitting element of a transmitting unit at first emitting times, and wherein a second plurality of measuring pulses (13) is emitted (102) during a second measuring interval (11) by means of the transmitting element of the transmitting unit at second emitting times. The method (100) comprises the reception (103) of reflected measuring pulses by means of a receiving element of a receiving unit assigned to the transmitting element at receiving times. The method further comprises the determining (106) of a first amount of times-of-flight for each received measuring pulse, wherein the first amount of times-of-flight is determined by using the first emitting times. The method (100) furthermore comprises the determining (107) of a second amount of times-of-flight for each received measuring pulse, wherein the second amount of times-of-flight is determined using the second emitting times. The method (100) comprises the creating (108) of at least one histogram (15) for the receiving element and the entering of the first amount and/or of the second amount of times-of-flight in the histogram.
Patent CA-3097495-A1 (CA)
Title: Method and system for treating a waste liquor of a caustic wash
Inventor: WELLENHOFER ANTON
IPC: C02F1/72
Filed: 2019-04-26
Abstract: The invention relates to a method for treating a waste liquor of a caustic wash, in which the waste liquor along with oxygen or an oxygen-containing gas mixture and vapour is supplied to an oxidation unit (1) and is subjected therein to a wet oxidation for a reaction time at a first temperature level and a first pressure level, wherein a three-phase component mixture comprising a gas phase, a liquid phase and solid particles is extracted from the oxidation unit (1) and subjected to a cooling process and a phase separation. According to the invention, the three-phase component mixture in the unchanged composition is first decompressed from a first pressure level to a second pressure level and thereby cooled to a second temperature level, and the three-phase component mixture decompressed to the second pressure level and cooled to the second temperature level is then subjected at least partially to another cooling process to reach a third temperature level and thereafter a phase separation. The invention also relates to a corresponding system.
Patent CA-3098987-A1 (CA)
Inventor: KORPMAN RALPH A
IPC: G06F16/835
Filed: 2020-03-30
Abstract: Divers modes de réalisation concernent des procédés, des systèmes, un appareil, des produits-programmes informatiques et/ou similaires pour gérer, ingérer, surveiller, mettre à jour et/ou extraire/récupérer des informations/données associées à un enregistrement électronique (ER) mémorisées dans une mémoire de données ER et/ou accéder à des informations/données à partir de la mémoire de données ER, les ER étant générés, mis à jour/modifiés et/ou faisant l'objet d'un accès par l'intermédiaire d'une ontologie de domaine reposant sur un graphique.
Patent CA-3099712-A1 (CA)
Title: Recepteurs d'antigenes chimeriques avec domaines de liaison modifies et utilisations associees
Inventor: BANDARA KANCHANA VERONIKA
IPC: C12N15/85
Filed: 2019-05-20
Abstract: La présente invention concerne un récepteur d'antigène chimérique (CAR) optimisé, et des cellules génétiquement modifiées les exprimant, qui peuvent cibler une gamme diverse de types de cancer. Plus spécifiquement, le CAR a une longueur de liaison optimisée qui facilite le ciblage et la lyse d'une large gamme de types de cellules cancéreuses par des lymphocytes T exprimant CAR.
Patent CA-3101014-A1 (CA)
Inventor: KAYYALI MAYA
IPC: G09B23/28
Filed: 2019-05-31
Abstract: A renal hilum surgical simulation system is provided. The renal hilum surgical simulation system includes simulated tissue layers and simulated renal organs and/or vasculatures. The renal hilum surgical simulation system is adapted for but not limited to laparoscopic donor nephrectomy surgical procedures.
Patent CA-3103186-A1 (CA)
Inventor: XIAO XIAO
IPC: C07K14/005
Filed: 2019-06-12
Abstract: The invention relates to synthetic adeno-associated virus capsids targeted to the liver and virus vectors comprising the same. The invention further relates to methods of using the vectors to target the liver and provide liver-specific expression, as well as transduce human primary hepatocytes and cell lines.
Patent CA-3104114-A1 (CA)
Title: High-frequency heating device
Inventor: LIU TUANFANG
IPC: H05B6/36
Filed: 2020-12-24
Abstract: ABSTRACT A high-frequency heating device includes a heating cup and a magnetic induction coil; the magnetic induction coil is a flat spiral structure. 7 Date Recue/Date Received 2020-12-24
Patent CA-3104512-A1 (CA)
Inventor: MORROW MARYANNE
IPC: G06Q20/38
Filed: 2019-06-21
Abstract: Blockchain, or distributed ledger network technology, facilitates and accelerates foreign currency (FX) transactions and makes them reliable and trusted by pre-qualifying participants in the transactions to participate. Pre-qualifying participants enables funding of the transaction before parties enter into a trade, reducing the time required to consummate a transaction. In one aspect, the credit aspect of these transactions is disaggregated from the transactions themselves, eliminating credit risk and delivery risk, among others. Immutability of data in the blockchain enhances transaction reliability, and promotes confidence on both sides of a given transaction. In another aspect, fully collateralized fiat coins (FCFC) residing within the blockchain are based on an underlying fiat currency. Within the blockchain, the FCFC are their own currency.
Patent CA-3108629-A1 (CA)
Title: System and method of operation for remotely operated vehicles for simultaneous localization and mapping
Inventor: VENDAS DA COSTA PEDRO MIGUEL
IPC: G06T7/579
Filed: 2018-08-08
Abstract: The present invention provides systems and methods for simultaneous localization and mapping from video with adversarial shape prior learning in real-time. For example, an unsupervised direct and dense SLAM may learn a geometry prior from data. Given a video sequence, a depth map of a target frame, as well as the target frame and the camera motions between the target frame and all the remaining frames may be output. Further, by fusing a camera motion estimate with a positional sensor' s output, positional drift and the need for loop closure can be avoided.
Patent CA-3109420-A1 (CA)
Inventor: LEMIEUX MARC-ANDRE
IPC: F24H3/04
Filed: 2019-08-20
Abstract: The invention allows producing air flow to either inflate a self-making bedding system via a first outlet, or to heat the air exiting the apparatus via a second, optionally a third, outlet, for controlling the air flow and the temperature sent into the self-making bedding system. The 5 apparatus is operated via an interface on the outside surface of the apparatus; a smartphone or tablet, an intelligent virtual/personal assistant or a computer including an application or software for wirelessly sending instructions to the apparatus, e.g. using BluetoothTM or Wifi; or a remote control. The invention is particularly useful for disabled persons for self-making their bed by directly controlling the apparatus via the application, with the possibility to use a 0 voice control system combined with the application, or to have the apparatus daily programmed for making the bed or controlling the temperature at specific time of the day.
Patent CA-3113150-A1 (CA)
Title: Volatile substance evaporation device
Inventor: RIERA GINER MONTSERRAT
IPC: A61L9/04
Filed: 2019-09-17
Abstract: The volatile substance evaporation device comprises a casing (1) provided with an evaporation surface (2), said casing (1) housing inside it a substrate (3) impregnated with said volatile substances, wherein said substrate (3) is a sheet which preferably comprises a plurality of grooves. It allows the device to have a similar diffusion value for a specific air flow and for a considerable internal temperature of the vehicle, thus ensuring continuous evaporation.
Patent CA-3113407-A1 (CA)
Inventor: CLUCK BRIAN K
IPC: E04B7/22
Filed: 2021-03-25
Abstract: Support members for a roof system are provided to allow for positioning panels of a roof apart from building members so that building components, such as insulation may be placed between the roof panels and the building members. The support members may be utilized in new buildings or to retrofit existing buildings. Each of the support members may comprise a single support member that has a base portion operatively coupled to an offset portion that is operatively coupled to an upper portion. One or more channels may be provided in the base portion, offset portion, and/or the upper portion to provide structural support and to allow the support members to be operatively coupled to each other and other building members without the need for additional components.
Patent CA-3115639-A1 (CA)
Inventor: POIRIER CEDRIC
IPC: F16C33/60
Filed: 2021-04-20
Abstract: An inner ring assembly for a ball bearing assembly includes a proximal inner ring made from a first material. The inner ring assembly further includes a distal inner ring made from a second material. The first material is different from the second material.
Patent CA-3116857-A1 (CA)
Inventor: EDWARDS MARK STEPHEN
IPC: F17C13/04
Filed: 2019-10-15
Abstract: A valve lever apparatus for use with fluid valves and a corresponding valve are disclosed. An example apparatus includes a valve stem (116) for a fluid valve, a pin (122) removably coupled to an end of the valve stem to receive a valve lever (120) to manually actuate the fluid valve, and a damping material (212, 214) to provide a damping effect between the valve stem and the valve lever.
Patent CA-3117584-A1 (CA)
Title: Roue dentee et pignon tendeur partageant une roue commune
Inventor: JONES BENJAMIN I
IPC: B62D55/14
Filed: 2019-10-16
Abstract: La présente invention concerne une roue dentée et un pignon tendeur partageant un élément roue commune (102) qui sont fabriqués par un procédé (300) qui consiste à utiliser un élément roue commune (302), utiliser une fixation annulaire à bride de pignon tendeur (304), et utiliser une fixation annulaire dentée (306).