baber/WOPTO huggingface dataset:
Patent CA-2192725-C (CA)
Title: Camptothecin derivatives
Inventor: TSUJIHARA KENJI
IPC: A61K47/48
Filed: 1996-12-12
Granted: 2004-04-20
Abstract: The present invention is directed to a camptothecin derivative comprising a compound of the formula [I]: (see formula I) wherein R1, R2, R3, R4 and R5 are (A) adjacent two groups combine to form alkylene, or both are H, and one of the remaining three groups is ~X n~Alk m~R6, and the other two are H, alkyl or halogen, or (B) adjacent two groups combine to form alkylene, and one of the carbon atoms of said alkylene group is substituted by ~X n~Alk m~R6, and the remaining three groups are H, alkyl or a halogen, and one or two ~CH2~ of the alkylene in (A) or (B) may optionally be replaced by ~O~, ~S~ or ~NH~, X is ~O~ or ~NH~, Alk is alkylene, R6 is ~NH2, (see formula II) or ~OH, m and n are both 0 or 1, or m is 1 and n is 0, which camptothecin compound is bound to a polysaccharide having carboxyl groups via an amino acid or a peptide, or a pharmaceutically acceptable salt thereof. Said camptothecin derivatives show enhanced antitumor activities but few side effects and are useful as a medicament.
Patent CA-2204195-C (CA)
Inventor: YAZICI BIRSEN
IPC: G01M13/04
Filed: 1997-05-01
Granted: 2003-07-15
Abstract: A motor current signal is monitored during a learning stage and divided into a plurality of statistically homogeneous segments representative of good operating modes. A representative parameter and a respective boundary of each segment is estimated. The current signal is monitored during a test stage to obtain test data, and the test data is compared with the representative parameter and the respective boundary of each respective segment to detect the presence of a fault in a motor. Frequencies at which bearing faults are likely to occur in a motor can be estimated, and a weighting function can highlight such frequencies during estimation of the parameter. The current signal can be divided into the segments by dividing the current signal into portions each having a specified length of time; calculating a spectrum strip for each portion; and statistically comparing current spectra of adjacent ones of the strips to determine edge positions for the segments. Estimating the parameter and the boundary of each segment can include calculating a segment mean (the representative parameter) and variance for each frequency component in each respective segment; calculating a modified Mahalanobis distance for each strip of each respective segment; and calculating the modified Mahalanobis mean and the variance for each respective segment. Each modified Mahalanobis mean can form a respective radius about a respective segment mean to define a respective boundary.
Patent CA-2207751-C (CA)
Inventor: SOLOVAY KENNETH S
IPC: A61F2/00
Filed: 1997-06-13
Granted: 2006-01-10
Abstract: A covered stent for treating a stenotic region in a blood vessel. The stent covering has different porosities in different regions. In those regions, typically the ends, where tissue ingrowth and re-endothelialization are desired, the stent covering is more porous, and in those regions were it is desirable to inhibit such ingrowth, the stent covering is substantially non-porous.
Patent CA-2208931-C (CA)
Inventor: PEDRAZZI RENATO
IPC: A61L2/18
Filed: 1997-06-17
Granted: 2006-04-25
Abstract: A procedure is claimed for disinfecting the hydraulic circuits of dialysis machines. An inlet (E) of a dialyser connects to the water supply. Lines (1, 2, 4a, 4b, 26) are reconfigured for machine operation, by connection to various consumables. During disinfection, the lines are shut off and interconnected as a closed network. The reservoir (40) connects near the inlet and contains concentrated disinfectant (I). Water and (I) are discharged into the circuit in set proportion, forming a bactericide (BC). The novelty is that when the circuit is full, influx is stopped; then the circuit is emptied. Intentionally, (I) remains in the reservoir, to which water is added, forming a second liquid, which with further water, is then admitted to the circuit as a bacteriostat (BT) which can remain there for at least 12 hours without causing corrosion. The circuit is left filled with BT.
Patent CA-2211183-C (CA)
Title: Electro-surgical tissue removal
Inventor: MORECI STEPHEN F
IPC: A61B17/00
Filed: 1996-01-30
Granted: 2006-11-28
Abstract: The invention features a bipolar electrosurgical apparatus having a first electrode (14) that has a relatively large surface area for creating a diffuse current sufficient to heat a region of tissue to coagulation temperatures and a second electrode (12) that has a relatively small surface area for creating a concentrated current region sufficient to heat tissue adjacent to the second electrode (12) to resection temperatures. The first and second electrodes (12, 14) are relatively positioned along a treatment path, such that tissue is coagulated and resected as the electrosurgical apparatus is disposed along the path.</SDOAB >
Patent CA-2212223-C (CA)
Inventor: GARDINER MARK E
IPC: F21V8/00
Filed: 1996-01-18
Granted: 2007-03-20
Abstract: A light directing film (50) including a first surface and a second structure d surface (52). The structured surface (52) includes a repeating pattern of prism zones including at least a first zone having a plurality of prism elements (56) with peaks disposed at a first distance from a reference plane and a second zone having a plurality of pris m elements (54) with peaks disposed less than the first distance from a reference plane. The width of the first zone preferably measures less than about 300 microns.
Patent CA-2212827-C (CA)
Inventor: NAKAMURA TAKAO
IPC: H01L39/14
Filed: 1997-08-13
Granted: 2000-05-09
Abstract: The invention provides a superconducting film structure comprising an oxide superconductor layer and a protective layer which covers and protects a surface of the oxide superconductor layer.
Patent CA-2215226-C (CA)
Title: System and method for driving a nematic liquid crystal
Inventor: OKITA MASAYA
IPC: G09G3/00
Filed: 1997-09-12
Granted: 2006-01-10
Abstract: A system for driving a nematic liquid crystal is used to display high definition color images at a high speed in a liquid crystal display device in which the nematic liquid crystal is confined between a common electrode and a segment electrode that are placed between two polarizing plates. The common electrode is supplied with a sequence of selection pulses, and the segment electrode is supplied with a voltage corresponding to image data to be displayed in response to the selection pulses. The segment electrode is further supplied with a voltage different from the voltage corresponding to the image data in intervals where the selection pulses are not applied to the common electrode.
Patent CA-2218196-C (CA)
Title: Method and apparatus for automatically generating a speech recognition vocabulary from a white pages listing
Inventor: GUPTA VISHWA
IPC: G10L15/18
Filed: 1997-10-14
Granted: 2004-12-14
Abstract: The invention relates to a method and apparatus for automatically generating a speech recognition vocabulary for a speech recognition system from a listing that contains a number of entries, each entry containing a multi-word identification data that distinguishes that entry from other entries in the list. The method comprises the steps of creating for each entry in the listing a plurality of orthographies in the speech recognition vocabulary that are formed by combining selected words from the entry. The words combination is effected by applying a heuristics model that mimics the way users formulate requests to the automated directory assistance system. The method is particularly useful for generating speech recognition vocabularies for automated directory assistance systems.
Patent CA-2218727-C (CA)
Title: Valve system
Inventor: SCHWELM HANS
IPC: F15B13/00
Filed: 1996-10-03
Granted: 2002-04-02
Abstract: A central block is disclosed for a pilot controlled valve system with seat a nd piston valves. The central block has a preferably standardised connection interface (12), a pilot valve interface (13) for receiving a pilot valve (32 ), a pump conduit (P), a tank conduit (T), a first work conduit (A), a second work conduit (B), a first control conduit x and a second control conduit y, as well as four valve reception cavities (34, 36) for receiving each one valve unit (C1, C2, C3, C4). In order to create a central block which may be universally used with any number of hydraulic circuits and whose connections  may be easily modified, the central block is composed of a middle block (2) to which are detachably secured two valve blocks (50, 60, 70, 80, 90, 100, 110,  120). The middle block (2) has two valve sides (6, 10) provided each with a valve block interface (22, 24) which receive each one valve block (50, 60, 7 0, 80, 90, 100, 110, 120). Each valve block (50, 60, 70, 80, 90, 100, 110, 120)  has two valve receiving cavities (34, 36) and the control conduits x and y a re arranged in such a way that each valve unit (C1, C2, C3, C4) may be driven b y a pilot valve (32) mounted at the pilot valve interface (13).
Patent CA-2223078-C (CA)
Inventor: GOLD LARRY
IPC: C12Q1/68
Filed: 1996-06-05
Granted: 2008-11-25
Abstract: La présente invention concerne des ligands nucléotidiques de haute affinité avec la Taq polymérase et la Tth polymérase thermostables. Spécifiquement, elle se rapporte à des ligands d'ADN capables de se fixer à la Taq polymérase et la Tth polymérase ainsi que les procédés permettant d'obtenir ces derniers. Lesdits ligands sont capables d'inhiber des polymérases à température ambiante.
Patent CA-2224978-C (CA)
Inventor: MCCARTHY LYNN J
IPC: B65D5/468
Filed: 1996-06-26
Granted: 2001-12-04
Abstract: A protective device (30) is provided for use with a packaging container (10)  having an interior (22), a wall (12) and a handhold opening (20) of a selected size an d configuration. Protective device (30) inhibits ingress and unwanted materials into interior  (22) through handhold opening (20) while permitting insertion of a hand for grasping handhold opening (20) and comprises a panel piece (32) having a surrounding peripheral edge (34) and a surrounding peripheral margin portion (36) adjacent to peripheral edge (34).  Panel piece (32) is sized and configured to have a panel size greater than the size and configuration of the handhold opening (20) so that margin portion (36) is securable to wal l (12) thereby to position and secure panel piece (32) in a secured state with panel piece (32) positioned over handhold opening (20). A first adhesive material (38) is disposed on peripheral margin portion (36) and operates to secure panel piece (32) in the secured state an d to seal margin portion (36) to wall (12) in an area surrounding handhold opening (20).</SDO AB>
Patent CA-2233234-C (CA)
Inventor: BRAUNSTEIN EDIT LIBIA
IPC: C12N9/98
Filed: 1996-10-22
Granted: 2008-12-23
Abstract: Cette invention concerne un procédé de préparation de cellulase cristalline qui consiste à préparer une solution aqueuse contenant l'enzyme cellulase et à ajouter à cette solution aqueuse un sel contenant un anion sélectionné dans le groupe constitué par un sulfate, un phosphate, un formate, un acétate, un sorbate, un chlorure, un bromure, un fluorure ou un iodure et un cation sélectionné dans le groupe constitué par le sodium, l'ammonium, le magnésium, le potassium, le calcium ou un mélange de ces derniers.
Patent CA-2235404-C (CA)
Title: Filter press with weight-responsive bumping of filter plates
Inventor: HIGGINS DAVID MARK
IPC: B01D25/32
Filed: 1996-09-13
Granted: 2007-03-06
Abstract: A shifter mechanism (22) for a filter press, which shifter mechanism incorporates a vibrating mechanism (71) for effecting bumping of individual filter plates (17) during the separation thereof from the closed stack to assist in dislodgement of the filter cake from the individual filter plates. The vibrating device can selectively vibrate or bump the individual filter plates responsive to the weight of the filter plate being bumped, whereby the vibrating device will be activated only upon sensing a filter plate having a weight greater than a predetermined value so as to be indicative of an undesired quantity of filter cake being adhered thereto.
Patent CA-2239035-C (CA)
Inventor: NAKATA KATSUYASU
IPC: A23L13/40
Filed: 1997-10-02
Granted: 2004-08-10
Abstract: A mineral-containing composition including enzymatically decomposed lecithin and a water-insoluble mineral. Since the mineral composition shows excellent dispersion stability of the water-insoluble mineral, the mineral composition can be utilized in a wide variety of fields such as foods, cosmetics and industrial products.
Patent CA-2242214-C (CA)
Inventor: ZIMCIK DAVID
IPC: F16F7/00
Filed: 1998-06-30
Granted: 2006-09-12
Abstract: A structural component having a stiffness which can be actively varied to control vibrations, for example in a helicopter rotor, an aircraft wing or tail, or in a robotic manipulator. The component has at least one recess or notch with opposed walls, which walls, in the absence of any intervening member, tend to move relative to each other when the component is stressed. A stiffness control element is situated in the recess or notch, this element comprising electrically or magnetically expandable material capable of being rapidly expanded from a first condition in which the element is out of contact with one of the walls, to an expanded condition in which the element extends across the recess or notch and transmits forces from one of the walls to the other, thus altering the stiffness of the component. The preferred expandable material is a stack of piezoelectric crystals.
Patent CA-2244221-C (CA)
Title: Procede et instrument d'anastomose destines a l'execution d'une anastomose termino-laterale
Inventor: RYGAARD JORGEN A
IPC: A61B17/115
Filed: 1996-02-29
Granted: 2002-08-13
Abstract: Cette invention concerne un instrument pour anastomose (201) et un procédé permettant d'effectuer une anastomose termino-latérale. Ledit instrument comporte un ensemble faisant office d'enclume (202A, 203, 203A) et comportant des évidements destinés à l'agrafage (204), un ensemble de blocage (205B, 205A) conçu pour avancer en direction de la face arrière de ladite enclume (203) et un ensemble d'agrafage (206, 206A) que l'on déplace en direction de ladite enclume (203). Ledit instrument se caractérise en ce que ces trois ensembles peuvent être fendus le long d'une surface commune de division et en ce que, en cours de fonctionnement, les pièces séparables de ces ensembles sont maintenues entre elles par une gaine commune élastique en caoutchouc (410) de façon à assurer un séquencement correct des déplacements relatifs lorsque l'on comprime conjointement ces trois ensembles au moyen d'un outil à main muni de mâchoires (202C, 206C). Une fois l'anastomose effectuée, on peut ouvrir la gaine en caoutchouc (410) en la coupant de manière à séparer l'une de l'autre les pièces séparables.
Patent CA-2244486-C (CA)
Title: Polyisocyanates containing iminooxadiazine dione groups and a process for their preparation
Inventor: MERTES HARALD
IPC: C08G18/02
Filed: 1998-08-03
Granted: 2007-10-23
Abstract: The present invention relates to a process for the preparation of polyisocyanates by oligomerizing isocyanates corresponding to formula I (OCN-CH2)X (I) wherein X represents the residue obtained by removing the OCN-CH2 group from a monomeric polyisocyanate, wherein the residue contains 3 to 20 carbon atoms and at least one NCO group, in the presence of hydrogen-polyfluoride oligomerization catalysts corresponding to formula II Mn+ n[F-((HF)m] (II) wherein M represents an n-valent cation and m is >= 0.1. The present invention is also directed to the polyisocyanates obtained by this process.
Patent CA-2246237-C (CA)
Inventor: ZOLIN PAUL F
IPC: G01M99/00
Filed: 1998-08-27
Granted: 2009-08-11
Abstract: A technique and apparatus for evaluating the degree of hydroenhancement achieved in a woven fabric. The degree of hydroenhancement is related to the permeability of the woven fabric (i.e., t he permeability of the woven fabric will decrease as the hydroenhancement increases). The hydroenhanced fabric is pulled over a vacuum source (while a constant vacuum is maintained) and the air flow through the fabric is measured. The air flow per unit area of fabric is then calculated and define d as the permeability. Alternatively, the permeability can be calculated by maintaining a constant air flow and measuring the vacuum drop associated wit h the treated fabric. The degree of hydroenhancement may then be assessed as related to this permeability measurement. The measurement may be performed on "wet" fabric immediately after it exits the hydroenhancement process and the permeability measurements used as a control signal for the hydroenhancement process (that is, to regulate the machinery used to impart the hydroenhanced quality to the fabric). Alternatively, the measurement may be performed on "dry" fabric and used, as an audit process, to assess the quality of the finished product.
Patent CA-2247159-C (CA)
Inventor: SUNDQUIST MATT
IPC: B65B43/39
Filed: 1997-09-23
Granted: 2004-09-21
Abstract: A carton flap hold down apparatus (25) for use in seating an open-ended sleeve-type carton (40) on a carton transport conveyor (27) is disclosed. The carton flap hold down apparatus has a plurality of aligned carton flap hold down rollers (61) disposed along a common longitudinal axis and extending in the direction of a path of travel, each support roller being supported for rotation on an elongate roller support bar (65). A mounting block (67) is fastened on a framework of the carton transport conveyor with respect to a carton flap score rail (31) thereof, the mounting block being spaced from the roller support bar, and an elongate intermediate member (66) is fastened to one end of the mounting block, and fastened at the other of its ends to the roller support bar.      The rollers are inclined toward the mounting block in the direction of the path of travel at an angle of 5° for holding, and pulling, the bottom flaps of the carton downwardly against the carton flap score rail to ensure that the carton remains fully seated on the carton transport conveyor as articles are transferred therein from an article selector device. The intermediate member is constructed and arranged to urge the roller support bar toward the carton flap score rail so that each one of the rollers is yieldably engaged on the carton flap score rail for slidably holding the bottom flap of the cartons thereon as the cartons advance along the path of travel.
Patent CA-2247236-C (CA)
Inventor: KUNO YUKINOBU
IPC: B65H18/26
Filed: 1998-09-11
Granted: 2006-12-19
Abstract: A veneer reeling apparatus for winding a veneer sheet round a freely rotatable take-up reel into a veneer roll is disclosed herein. Veneer sheet is transferred by a plurality of spaced conveyer belts extending below the take-up reel. The take-up reel is removably supported by movable reel carriages for movement therewith toward and away from the conveyer belts. Each belts is urged toward the take-up reel to be kept in resiliently pressing contact with veneer roll for friction driving. There is provided a detector for monitoring an increment in diameter of the veneer roll during reeling operation and generating a signal in response to the detection of a predetermined amount of increment in the roll diameter. A control responding to the signal from the detector provides a command signal to move the reel carriages hence the take-up reel carried thereby upward or away from the belt so as to compensate for the increment in diameter of the veneer roll.
Patent CA-2250704-C (CA)
Title: Glial cell line-derived neurotrophic factor receptor
Inventor: JING SHUQIAN
IPC: C07K14/705
Filed: 1997-04-15
Granted: 2005-04-12
Abstract: The present invention relates to glial cell line-derived neurotrophic factor (GDNF), a potent neurotrophin that exhibits a broad spectrum of biological activities on a variety of cell types from both the central and peripheral nervous systems. The present invention involves the cloning and characterization of a high affinity receptor for GDNF. This molecule has been named GDNF receptor (GDNFR) since it is the first known component of a receptor system. Nucleic acid and amino acid sequences are described for GDNFR protein products. A hydrophobic domain with the features of a signal peptide is found at the amino terminus, while a second hydrophobic domain at the carboxy terminus is involved in the linkage of the receptor to the cell membrane. The lack of a transmembrane domain and cytoplasmic region indicates that GDNFR requires one or more accessory molecules in order to mediate transmembrane signaling. GDNFR mRNA is widely distributed in both nervous system and non-neural tissues, consistent with the similar distribution found for GDNF.
Patent CA-2251720-C (CA)
Title: Tape for use in manufacturing electrochromic devices
Inventor: CHEN KEJIAN
IPC: B32B27/00
Filed: 1997-03-17
Granted: 2007-01-30
Abstract: A tape (30) that includes an electronically conductive flexible substrate (32), a release layer (42) and an adhesive (40) comprising an ion-intercalating material (36) and electrochromic devices and glazing units prepared using this tape.
Patent CA-2252180-C (CA)
Inventor: AMIN UMESH J
IPC: H04M15/08
Filed: 1998-10-29
Granted: 2002-04-23
Abstract: A method provides a wireless subscriber with the capability of selectively changing the assignment of the party that pays for a call for which the wireless subscriber is terminating terminal. The subscriber can register with a switching center and select an option that places the payment responsibility on a calling party. Then when a calling party initiates a call tothe wireless subscriber the switching center forwards a notice to the calling party that the responsibility for paying for the call rests with the calling party. The wireless subscriber can at any subsequent time elect to accept the responsibility for calls to the subscriber.
Patent CA-2257423-C (CA)
Inventor: WRIGHT ANDREW S
IPC: H04L12/56
Filed: 1997-05-06
Granted: 2003-09-23
Abstract: Les tentatives d'enregistrement que fait un terminal (10, 20, 30, 40, 50, 60) fonctionnant en mode conflit d'accès pour communiquer avec un système central (100) sont commandées par transmission au terminal, par le système central, d'un indice d'enregistrement (510), selon une périodicité spécifiée, et par modification de la valeur de l'indice d'enregistrement quand le terminal devrait tenter de s'enregistrer auprès du système central. Un indicateur de mode (515) est transmis au terminal par le système central, selon une périodicité prédéterminée, et la valeur de l'indicateur de mode est modifiée durant la reprise du système central après une panne majeure, de façon que le terminal ne tente pas immédiatement de s'enregistrer auprès du système central. Durant la reprise, le terminal est capable de s'associer avec l'un des sous-intervalles faisant partie d'une pluralité de sous-intervalles. Le système central transmet un désignatif de sous-intervalle (520) au terminal selon une certaine périodicité pendant la reprise et modifie la valeur du désignatif du sous-intervalle après un nombre prédéterminé de périodes régulières. Le flux de tentatives d'enregistrement faites par une communauté de terminaux est ajusté de façon à passer, après une panne, d'une situation dans laquelle toute la communauté de terminaux est en conflit pour s'enregistrer à une situation dans laquelle des sous-groupes de la communauté tentent de s'enregistrer dans leurs sous-intervalles respectifs.