baber/WOPTO huggingface dataset:
Patent CA-2165162-C (CA)
Title: Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
Inventor: BUJARD HERMANN
IPC: C07K14/00
Filed: 1994-06-14
Granted: 2000-05-23
Abstract: Transgenic animals carrying two transgenes, the first coding for a transactivator fusion protein comprising a tet repressor and a polypeptide which directly or indirectly activates in encaryotic cells, and the second comprising a gene operably linked to a minimal promotor operably linked to at least one tet operator sequence, are disclosed. Isolated DNA molecules (e.g., targeting vectors) for integrat-ing a polynucleotide sequence encoding a transac-tivator of the invention at a predetermined location within a second target DNA molecule by homolo-gous recombination are also disclosed. Transgenic animals having the DNA molecules of the invention integrated at a tet operator location in a chro-mosome by homologous recombination are also en-compassed by the invention. Methods to regulate the expression of a tet operator linked gene of in-terest by administering tetracycline or a tetracycline analogue to an animal of the invention are also dis-closed. The regulatory system of the invention al-lows for conditional inactivation or modulation of expression of a gene of interest in a host cell or an-imal.
Patent CA-2165542-C (CA)
Title: Sealing apparatus for packaging containers
Inventor: OHLSSON PER
IPC: B31B50/66
Filed: 1994-07-15
Granted: 2003-04-08
Abstract: A sealing apparatus for packaging containers includes an anvil  (23) for supporting a sealing fin portion (21), a horn (35) compose d of a columnar portion and a converging portion (35b), and means for pressing said sealing fin portion (21) against the anvil (23) through the tip of the horn (35) and for transmitting ultrasonic vibration to the sealing fin portion (21).  Ultrasonic vibration is transmitted to the packaging material through the horn (35) so that each pair of opposing sealant layers is fused and sealed.  In addition, means for absorbing ultrasonic vibration is disposed between the tip of the horn  (35) and an edge portion (25) of the sealing fin portion (21) so th at ultrasonic vibration is absorbed.  When ultrasonic vibration is transmitted to the sealing fin portion (21), the sealing fin portion  (21) is excited to transmit the vibration toward the edge portion ( 25).  However, since the ultrasonic vibration is absorbed by the means fo r absorbing ultrasonic vibration, the ultrasonic vibration is not transmitted to the edge portion (25).  Accordingly, it is possible to prevent the generation of dust from an end surface of the paper substrate which is exposed at the edge portion (25) of the sealing fin portion (21) .
Patent CA-2167213-C (CA)
Title: Method for using lightweight concrete, for producing a combination therefrom and a combination produced thereby
Inventor: GROH RICHARD E
IPC: C04B28/02
Filed: 1994-07-08
Granted: 2003-09-30
Abstract: This invention is directed to a light-weight concrete combination. The combina-tion includes a lightweight concrete product having auxiliary structures, such as at least one fastener, embedded therein. The light-weight concrete product comprises (a) ce-ment and (b) a lightweight additive material. The invention also relates to a method for using the lightweight concrete product, and to a method for producing the lightweight concrete combination.
Patent CA-2168006-C (CA)
Inventor: MCDONOUGH JAMES M
IPC: F23Q2/46
Filed: 1994-07-26
Granted: 2001-05-15
Abstract: Le briquet (10) de la présente invention comporte une protection élastiquement déformable (60) qui recouvre une partie de l'ensemble molette (14). Afin d'actionner le briquet (10), l'utilisateur exerce une pression suffisante pour abaisser la protection (60) avant de faire tourner l'ensemble molette (14). La présente invention comporte des méchanismes de retenue (61) qui rendent le retrait de la protection (60) plus difficile. De plus, le briquet (10) de la présente invention comporte des éléments d'arrêt (46) qui empêchent l'ensemble molette (14) de tourner lorsque l'utilisateur tente de libérer le combustible avant de faire tourner l'ensemble molette (14).
Patent CA-2169756-C (CA)
Title: Additifs antimicrobiens ameliorant la suspension de particules
Inventor: GUTZMANN TIMOTHY ALLEN
IPC: A01N25/30
Filed: 1994-10-17
Granted: 2003-04-15
Abstract: L'invention concerne une composition concentrée antimicrobienne améliorant la suspension de particules. Ce concentré peut s'utiliser dans tout type de milieu, y compris des milieux de traitement et de services alimentaires, tels que des brasseries ou des installations de mise en bouteilles. De façon générale, le concentré peut être entraîné dans un produit ou introduit directement dans le milieu. Il comprend généralement un composé cationique antimicrobien, tel qu'un composé d'ammonium quaternaire et un tensioactif de suspension de particules, tel qu'un sel d'acide propionique amphotère.
Patent CA-2169900-C (CA)
Title: Hue and lightness identification system for dental products
Inventor: GRUTZNER ANDREAS ERNST
IPC: A61C19/04
Filed: 1996-02-20
Granted: 2007-07-24
Abstract: A system for identification of hue and lightness of dental products formed from dental material within enclosures an alpha series of at least three caps (A) having an alpha cap hue and supported by enclosures enclosing dental materials which are polymerizable to form an alpha series of dental products having an alpha product hue. The system includes a beta series of at least three caps (B) having a beta cap hue supported by enclosures enclosing dental materials which are polymerizable to form dental products having a beta product hue. The system includes a first series of at least three caps (1) having a first cap lightness and each of said first caps being supported by an enclosure enclosing a dental material which is polymerizable to form a dental product having a first product lightness. The system includes a second series of at least three caps (2) having a second cap lightness, and each of said second caps being supported by an enclosure enclosing a dental material which is polymerizable to form a dental product having a second product lightness.
Patent CA-2172379-C (CA)
Inventor: SUTHERLAND ROBERT L
IPC: B65D71/12
Filed: 1995-06-12
Granted: 2006-10-24
Abstract: A wrap-around carrier (10) with partial end panels. The partial end panels are formed by end panel flaps (30) connected to the bott om panel flaps (24, 26) of the carrier and in combination with overlying end c losure flaps (28) connected to the side panels (12) of t he carrier. A gusset panel (74) connects adjacent end panel flaps and end closure flaps. Upper corner webs (32) may also be provided to form a barrier for restraining outward movement of the upper portion of packaged articles ( C) at the ends of the carrier.
Patent CA-2176775-C (CA)
Title: System and method for database access administration
Inventor: BAKER BRENDA SUE
IPC: G06F12/00
Filed: 1996-05-16
Granted: 1999-08-03
Abstract: A system and method for selectively controlling database access by providing a system and method that allows a network administrator or manager to restrict specific system users from accessing information from certain public or otherwise uncontrolled databases (i.e., the WWW and the Internet). The invention employs a relational database to determine access rights, and this database may be readily updated and modified by an administrator. Within this relational database specific resource identifiers (i.e., URLs) are classified as being in a particular access group. The relational database is arranged so that for each user of the system a request for a particular resource will only be passed on from the local network to a server providing a link to the public/uncontrolled database if the resource identifier is in an access group for which the user has been assigned specific permissions by an administrator. In one preferred embodiment, the invention is implemented as part of a proxy server within the user's local network.
Patent CA-2185712-C (CA)
Inventor: WILLIAMS DAVID A
IPC: A61K47/48
Filed: 1995-03-27
Granted: 2002-10-22
Abstract: Procédé permettant d'améliorer l'efficacité de la transduction de cellules hématopoïétiques ou autres par des rétrovirus. Le procédé consiste à infecter les cellules en présence de fibronectine ou de fragments de fibronectine. La fibronectine et ses fragments renforcent considérablement le transfert génétique à médiation rétrovirale dans les cellules, particulièrement les cellules hématopoïétiques comprenant la descendance engagée et les cellules souches hématopoïétiques primitives. L'invention porte également sur de nouvelles méthodes de somatothérapie génétique exploitant ce transfert génétique amélioré, sur des populations de cellules hématopoïétiques et sur de nouvelles constructions tendant au renforcement du transfert d'ADN par médiation virale dans des cellules et leur utilisation.
Patent CA-2187941-C (CA)
Inventor: SEMERIA DIDIER
IPC: C07C215/10
Filed: 1996-10-15
Granted: 2001-01-02
Abstract: Prepn. of 2-amino-alkane-1,3,4-triol derivs. or their salts comprises the single step reaction between an alkyl-2-oximino-3-oxo-4-acyloxyalkanoate of formula R1-CH(OCOR3)-C(O)-C(=NOH)-CO2R2 (I) in a solvent in the presence of at least one hydride. R1 = 4-28C alkyl, alkenyl or aralkyl (opt. interrupted by ether bridges, opt. contg. hydroxyl and/or 1-8C acyloxy); R2 = 1-5C alkyl or alkenyl (opt. interrupted by ether bridges); R3 = 1-6C alkyl, alkenyl or aryl.
Patent CA-2188262-C (CA)
Title: Method for fractionating a solution
Inventor: KUISMA JARMO
IPC: B01D15/36
Filed: 1995-04-19
Granted: 2006-08-29
Abstract: The invention relates to a method for fractionating a solution by a chromato graphic simulated moving bed method in which the liquid flow is effected an a system comprising at least two sectional packing mater ial beds in different ionic forms. The fractions enrich ed with different components are recovered during a multi-step sequence comprising t he following operations, i.e. phases: feeding phase, elu ting phase and recycling phase. The liquid present in the sectional packing mate rial beds with its dry solids concentration profile is r ecycled during the recycling phase in a loop comprising one, two or more sectional p acking material beds. The method can be employed for fractionating sulphite cooking liquor, molasses and vinasse, for example.</S DOAB>
Patent CA-2188592-C (CA)
Inventor: FUKUSHIMA TOSHIHIRO
IPC: B23K11/06
Filed: 1996-02-13
Granted: 1999-08-31
Abstract: Seam welding process and apparatus, wherein two plate-like workpieces (12) are fed in a feed direction toward a pair of roller electrodes (20), by guide rollers (14) rotated by a driving device (76), while the workpieces are guided by a guiding device (14, 18) such that the edge portions overlap each other by a predetermined lap amount (S) so that the overlapping edge portions are forced together by the roller electrodes, and the edge portions are continuously welded together with a welding current being applied between the roller electrodes.
Patent CA-2189789-C (CA)
Title: Ligne de transport electrique enterree equipee d'un dispositif de refroidissement
Inventor: THURIES EDMOND
IPC: H02G5/10
Filed: 1996-11-06
Granted: 1999-09-28
Abstract: La présente invention concerne une ligne blindée de transport  d'énergie  enterrée  et  comportant  dans  une enveloppe métallique (2) au moins une barre conductrice (1A, 1B,  1C),  cette  ligne  étant  équipée  d'un  dispositif  de refroidissement par transfert de chaleur de ladite enveloppe (2)  vers la surface du sol  (14)  constitué d'une structure métallique fixée à ladite enveloppe  (2) et s'étendant vers la  surface  du  sol  (14).  Ladite  structure  comprend  une pluralité de premières plaques  (14A)  verticales reliées à l'enveloppe  (2)  et de dimension verticale déterminée pour que  leur  coté  supérieur soit  à  une  profondeur  calculée admissible.
Patent CA-2195826-C (CA)
Title: Method of illustrating an erasable printing form
Inventor: SCHUSTER ALFONS
IPC: B41C1/10
Filed: 1997-01-23
Granted: 2001-09-04
Abstract: A method for imaging a printing form in which the printing form is charged on its entire surface and is coated on its entire surface with particles, in particular toner particles, which bear the opposite charge.  The layer formed by the particles is then fixed in accordance with the image by a beam, in particular a laser beam, and especially by infrared radiation, on the surface of the printing form or ablated in accordance with the image. Thereupon, the unfixed portions of the layer are removed or the non-ablated portions are fixed by full-surface heat treatment.
Patent CA-2202654-C (CA)
Title: Mesure des seuils de discrimination sensorielle respiratoire
Inventor: MARTIN JOHN H
IPC: A61B5/00
Filed: 1995-10-13
Granted: 2007-05-22
Abstract: L'invention concerne un appareil et un procédé pour mesurer objectivement des seuils de discrimination sensorielle au niveau d'une région d'essai dans les voies aérodigestives supérieures d'un patient. L'appareil comporte une source haute pression (1), un régulateur de pression (3), une soupape (5), un tube en forme de Y (19), un transducteur de pression (13) et un affichage (15).
Patent CA-2208575-C (CA)
Inventor: DESMARAIS THOMAS ALLEN
IPC: C08F2/32
Filed: 1996-01-11
Granted: 2001-03-27
Abstract: Mousses absorbantes capables d'absorber et de répartir des fluides aqueux, particulièrement les fluides corporels évacués, tels que l'urine. Ces mousses absorbantes combinent des pressions d'absorption capillaire relativement élevées et des propriétés de capacité relativement au poids qui leur permettent d'absorber le fluide, avec ou sans l'aide de la gravité. Ces mousses absorbantes transfèrent efficacement le fluide à des matériaux de stockage à pression d'absorption plus élevée, notamment des éléments de stockage de fluides absorbants à base de mousse, sans se rétracter. Ces mousses absorbantes sont réalisées par la polymérisation d'émulsions à phase dispersée importante.
Patent CA-2208971-C (CA)
Title: Boronic acid and ester inhibitors of thrombin
Inventor: PACOFSKY GREGORY JAMES
IPC: C07D249/08
Filed: 1995-12-13
Granted: 2001-01-16
Abstract: Novel boronic acid and ester and carboxyl-modified amino acid compounds of formula (I): R1-Z-CHR1-A, which are inhibitors of trypsin-like enzymes, are disclosed, where R1, Z, R2 and A are defined within.
Patent CA-2214427-C (CA)
Inventor: RABIN STEVEN B
IPC: G01N30/96
Filed: 1996-02-29
Granted: 2002-04-23
Abstract: A method of anion or cation analysis by ion chromatography (10) by chromatographic separation of ionic species in a sample solution in an eluent comprising an electrolyte using electrolytic chemical regeneration of the suppressor (11) by applying an electrical potential across the flow channels of a membrane suppressor (11), and detection (12) of the ionic species, the improvement comprising applying said electrical potential for a sufficient time to regenerate said suppressor (11), but discontinuing application of the electrical potential during separation and detection of the anions or cations, thereby reducing background noise concomitant to said electrical potential.
Patent CA-2216810-C (CA)
Inventor: MCMICHAEL JOHN
IPC: A61K31/00
Filed: 1996-10-30
Granted: 2005-04-26
Abstract: The present invention is directed to methods of treating benign prostatic hypertrophy comprising the step of administering to a subject suffering from benign prostatic hypertrophy a chorionic gonadotropin or a pharmaceutically active fragment or derivative thereof in an amount effective to alleviate one or more symptoms of benign prostatic hypertrophy.
Patent CA-2219239-C (CA)
Inventor: OYAMA NOBUO
IPC: F21V7/00
Filed: 1997-10-23
Granted: 2006-02-14
Abstract: A lighting device in a controlled distribution type provides a high energy efficiency and desired distribution of light. Such lighting device is obtained by redirecting and condensing the flux of a lamp 1 with an ellipsoidal reflector 2 alone or together with a spheric reflector 3, further redirecting visible or infrared rays in the flux to have visible rays entered to a transparent diffuser which embodies a plurality of ridges or ridges and grooves and diffuses incident light in single axis and further controlling such diffused rays with a reflector or a set of reflectors 6.      Such lighting device is used to constituto another lighting device in a radiation panel type.
Patent CA-2226350-C (CA)
Title: Acier pour le formage a froid
Inventor: ADRIEN JACQUES
IPC: C22C38/26
Filed: 1998-02-03
Granted: 2002-09-10
Abstract: Acier pour le formage à froid obtenu par fusion et affinage d'un alliage caractérisé en ce que l'alliage a la composition pondérale suivante :   Carbone             0,80 - 1,50  % Manganèse                < 1     % Silicium                 < 1     % Phosphore                ~ 0,030 % Soufre                   ~ 0,005 % Chrome              6,25 - 9     % Nickel                   < 0,50  % Molybdène           1,80 - 3     % Aluminium                ~ 0,15  % Vanadium            0,20 - 0,40  % Niobium             0,60 - 1,50  % Azote                    < 150 ppm Oxygène                  < 50  ppm  Titane ou            500 - 1500ppm Zirconium   Le  complément  étant  du  fer  plus  les  impuretés caractéristiques de la pratique de la fabrication du métal.
Patent CA-2229053-C (CA)
Title: Colour detection method
Inventor: KIRITCHENKO ALEXANDRE IVANOVIT
IPC: G01J3/46
Filed: 1996-04-24
Granted: 2006-11-14
Abstract: A method of detecting the colour of an article such as gambling chips to permit the different colour chips to be sorted. The method comprises sensing the colour of the article at a plurality of places thereon by moving the article relative to colour sensing means, and integrating the colour measured with respect to time.
Patent CA-2232413-C (CA)
Title: Compositions adoucissantes stabilisees pour tissus
Inventor: CEULEMANS RAPHAEL ANGELINE A
IPC: D06M13/02
Filed: 1996-09-13
Granted: 2002-11-12
Abstract: L'invention concerne des compositions adoucissantes liquides stabilisées pour tissus, qui comprennent: a) un ou plusieurs composés adoucissants biodégradables pour tissus et b) un ou plusieurs composés d'acides gras. Dans ces compositions, le rapport entre les adoucissants pour tissus et les composés d'acides gras est compris entre 25:1 et 6,5:1.
Patent CA-2235493-C (CA)
Title: Dispositif a lit fluidise circulant pour procedes chimiques et physiques
Inventor: RUOTTU SEPPO
IPC: B01J8/18
Filed: 1997-09-01
Granted: 2005-12-06
Abstract: L'invention concerne un dispositif convenant pour mettre en oeuvre des procédés physiques et chimiques constitués de deux procédés unitaires séparés qui utilisent un milieu à base de matière particulaire, le second procédé servant à régénérer le matériau particulaire contaminé durant le premier. Le dispositif comprend un premier réacteur (1-3), qui effectue la réaction de la première unité; un second réacteur (4-6), qui effectue la réaction de la seconde unité; disposé entre le premier (1-3) et le second réacteur (4-6), un premier canal de transfert (20) sert à transporter le matériau particulaire contaminé depuis le premier réacteur jusqu'au second; et, disposé entre le second (4-6) et le premier réacteur (1-3), un second canal de transfert (29) sert à transporter la matière particulaire régénérée depuis le second réacteur jusqu'au premier. Selon l'invention, le premier réacteur (1-3) comprend un réacteur à lit fluidisé circulant qui comporte un espace de réaction dont la section axiale est annulaire, et le second réacteur (4-6), qui comprend un réacteur à lit fluidisé circulant entourant le premier réacteur d'une manière concentrique et symétrique, comporte également un espace de réaction dont la section axiale est annulaire. La configuration de l'invention permet de construire également de grands appareils ayant un rapport hauteur/diamètre faible, en minimisant l'encombrement/les besoins en surface de l'installation et en réduisant sensiblement les problèmes associés à la dilatation thermique.
Patent CA-2237593-C (CA)
Inventor: CHANDRAN RAVI
IPC: F26B23/02
Filed: 1996-11-12
Granted: 2002-03-12
Abstract: L'invention concerne des procédés de séchage et de chauffage et un appareil comprenant un dispositif de combustion pulsatoire pouvant être utilisé dans un système de séchage ou de chauffage. L'appareil comporte généralement un dispositif de combustion pulsatoire (12) pour la combustion d'un combustible et la production d'un flux pulsé de produits de combustion et une onde de pression acoustique. Le dispositif de combustion pulsatoire (12) présente une chambre de combustion (18) reliée à au moins un tube à résonance (20). Une chambre à résonance (14) entoure au moins une partie du dispositif de combustion pulsatoire et comporte une buse (34) située en aval du tube à résonance (20). La buse (34) accélère les produits de combustion s'écoulant dans celle-ci et crée une charge dynamique pulsatoire. Dans un système de séchage (10), la buse (34) débouche dans un chambre de séchage (16) dans laquelle les produits de combustion sont en contact avec un flux d'alimentation. Lorsqu'elle est utilisée dans un système de chauffage (70), ladite buse (34) débouche dans une buse éjecteuse (72) qui mélange les produits de combustion avec un flux recyclé de produits de combustion pour former un effluent qui est envoyé à un dispositif d'échange de chaleur (74).
Patent CA-2239770-C (CA)
Title: Waterproof membrane
Inventor: CHEETHAM JOHN O
IPC: E04B1/62
Filed: 1996-12-23
Granted: 2005-08-02
Abstract: A waterproof membrane (1) for use as a waterproof barrier between or externally to building components, the said membrane (1) having protrusions or studs (6, 7, 8, 9) which function as distance pieces in order to ensure ventilation or drainage along the waterproof barrier. Additionally the membrane (1) is provided with a pattern of crossing, linear folding lines (2, 3, 4, 5) impressed in the membrane (1). It is thus possible to fold the membrane (1) round external or into internal corners of building constructions eliminating the use of additional components whilst maintaining continuity in ventilation or drainage.
Patent CA-2239904-C (CA)
Title: Inhibitors of interleukin-1.beta. converting enzyme
Inventor: LIVINGSTON DAVID J
IPC: C07D413/12
Filed: 1996-12-20
Granted: 2010-01-19
Abstract: The present invention relates to novel classes of compounds which are inhibitors of interleukin-1,6 converting enzyme. The ICE  inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-.gamma.- mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-.gamma.-mediated diseases and decreasing IGIF and IFN-.gamma.  production using the compounds and compositions of this invention.  This invention also relates to methods for preparing N-acylamino compounds.