baber/WOPTO huggingface dataset:
Patent IE-780629-L (IE)
Title: Theophyllylsugar compounds
IPC: C07H15/26
Filed: 1978-03-30
Abstract: Hypolipemic non-glycosidic theophylline-sugar compounds having the formula <IMAGE> are disclosed, as are a method for making them and methods and compositions for treating hyperlipemia with the compounds.
[US4151277A]
Patent IE-43708-L (IE)
Title: D-homosteroid carboxylic acids
IPC: A61K31/22
Filed: 1976-03-30
Abstract: The present disclosure relates to steroid carboxylic acids and derivatives thereof. More particularly, the disclosure is concerned with D-homosteroid carboxylic acids and their derivatives, a process for the preparation thereof and pharmaceutical compositions containing same. The instant compounds are active endocrinal agents, especially as antiinflammatory agents.
Patent IE-810746-L (IE)
Title: Preparing vincristine
IPC: C07D519/04
Filed: 1981-04-01
Abstract: Vincristine is prepared from VLB sulfate or free base by oxidation with an acidic ferrous perchloratehydrogen peroxide oxidation reagent at about -30 DEG C.
[US4303584A]
Patent IE-36487-L (IE)
Title: Preserving fresh meat.
IPC: A23B4/10
Filed: 1972-06-08
Abstract: 1354067 Preserving meat M & H STEMMLER GmbH 12 June 1972 [27 April 1972] 27310/72 Heading A2D Fresh meat is preserved by treating the meat with a distilled, edible, fully acetylated monoglyceride, said monoglyceride being maintained at a temperature above its solidifying point and not more than 16C. The meat may be immersed in or sprayed with the said monoglyceride. The fully acetylated monoglyceride may be prepared from lard, cotton seed oil or partially hydrated vegetable oil.
[GB1354067A]
Patent FI-811682-L (FI)
Inventor: SCHALLY ANDREW VICTOR
IPC: A61K38/04
Filed: 1981-06-01
Abstract: Disclosed herein are peptide analogs of the luteinizing hormone releasing hormone (LH-RH) which are potent antagonist of LHRH. The analogs differ in structure from LH-RH by having different amino acid residues at positions 1, 2 and 6, and optionally at positions 3 and 10. Methods for preparing and using these analogs are described.
Patent FI-813941-L (FI)
Inventor: RAABE THOMAS
IPC: C07D237/22
Filed: 1981-12-08
Abstract: Basically-substituted pyridazines of the formula:    <IMAGE>  (I) wherein R1, R2 and R3, independently of one another, denote hydrogen, halogen, hydroxyl, nitro, trifluoromethyl, alkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, alkoxy, hydroxyalkoxy, alkoxy-alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, phenalkoxy, alkanoyl, alkanoylamino and -NH-CO-R9, R9 representing morpholino, piperidino or 1-pyrrolididinyl, or an optionally substituted ureido radical, R4 denotes hydrogen or lower alkyl and W denotes hydrogen, chlorine or bromine; and the acid-addition salts thereof are useful alone or in pharmaceutical preparations for treating cardiac complaints, circulatory complaints and high blood pressure. Several methods for preparing the basically-substituted pyridazines are also provided.
Patent FI-844472-L (FI)
Inventor: MACOVSKI ALBERT
IPC: G01R33/48
Filed: 1984-11-14
Abstract: NMR imaging even of temporary variations present in the magnetic field is achieved by the invention. The volume 10 is excited using broadband excitation 14, 15. Using a small coil 28 a signal is received in the plane of interest and this signal is used to determine the frequency for subsequent plane-selecting excitation. A similar coil 21, 23 can be used to receive a signal used to image the plane employing projections that all run in the same direction. This later signal is used to form demodulation signals (ω2 - ω1) to resolve the chosen plane into its components. Shifts in the magnetic field B0 are compensated in both methods, which includes the excitation and decoding signals. <IMAGE>
Patent FI-853737-L (FI)
Inventor: KALVODA JAROSLAV
IPC: C07D205/08
Filed: 1985-09-27
Abstract: (4R)-3,4-trans-disubstituted azetidinones of the formula <IMAGE> in which R1 denotes hydrogen or lower alkyl, R2 denotes hydrogen or a hydroxyl-protecting group R, R3 denotes phenyl, substituted phenyl or lower alkyl and R4 denotes hydrogen or an amino-protecting group R, are valuable intermediates for the preparation of optically active penem or carbapenem compounds which act as antibiotics. The processes comprise the ring closure between carbon atoms 3 and 4 of the azetidinone ring.
Patent IE-36587-L (IE)
Title: Mass transfer device
IPC: B01D63/14
Filed: 1972-07-24
Abstract: A foldable cardboard backing is secured to one surface of a flexible mass transfer membrane to enable rapid formation of a folded multi-layered device by compressing the backing and membrane connected thereto into folds and then fixing the folds by sealing their ends.
[US3757955A]
Patent IE-33522-L (IE)
Title: Semi-trailer vehicles
IPC: B60G11/14
Filed: 1969-08-15
Abstract: 1,210,833. Semi-trailer suspensions. PEAK TRAILERS Ltd. 23 July, 1969 [21 Aug., 1968], No. 39952/68. Heading B7D. A semi-trailer vehicle suspension system comprises a frame formed of members 10, 11, 12 on which a pair of "T"-frames 16 are pivoted about pins 15, each frame leg 16b having extending therefrom a stub axle 17 carrying double wheels 19, and there extending between each frame 16 and its adjacent frame member 11 a coil spring 24 through which extends an hydraulic damper 27. Stops 40, 41 limit the spring movement. Brake shoes within drums 30 are operated by rod 32 either by a hand brake lever by means of rod 35, or by a pneumatic actuator by means of rod 36. Gusset plates 21 support the spring 24 and also bearings 22 for pivot pins 15. The frame formed of members 10, 11 and 12 may support the two pairs of "T"-frames 16, or alternatively two systems as above described may be provided in tandem, Fig. 5. In this latter embodiment the upper ends of the springs 24 contact the longer sides of bell-crank levers 42 pivoted at 43, and connected between their shorter sides by an equalizing rod 46. The wheels on each side of the trailer vehicle may alternatively be hydraulically connected, and more than two sets of wheels provided.
[GB1210833A]
Patent IE-42947-L (IE)
Title: Pharmaceutical compositions containing acetic acid¹derivatives
IPC: C07C29/09
Filed: 1975-06-12
Abstract: 1485269 Pharmaceutical compositions containing acetic acid derivatives LABAZ 12 June 1975 [26 June 1974] 28416/74 Heading ASB [Also in Division C2] Pharmaceutical or veterinary compositions, usable in treating non-human subjects with central neurological disorders, comprise as an active ingredient an acetic acid derivative of formula: where R represents where R, and R 2 may be the same or different and each represent an alkyl group with 1-4 carbon atoms, n is an integer from 1-3 inclusive and R 3 and R 4 , which are identical, each represent a straight chain alkyl radical with 1-4 carbon atoms, in association with a carrier or excipient other than Ordinary tap water or a common organic solvent. Preferred active ingredients are 3-n-propyl hexanoic acid; 4-n-propyl-heptanoic acid, 3-n-butyl heptanoic acid, 3-Methyl-butanoic acid, 3-ethyl-pentanoic acid and 5-n-propyl octanoic acid. The composition is preferably in a unit dosage form for rectal or oral administration.
Patent IE-39776-L (IE)
Title: Inflatable rubber tubes
IPC: B29K105/24
Filed: 1973-08-09
Abstract: 1443420 Moulding inflatable rubber tubes DUNLOP Ltd 10 Aug 1973 [18 Aug 1972] 38542/72 Addition to 1367084 Heading B5A An improvement in or modification of the invention in Specification No. 1,367,084 comprises moulding an annular inflatable rubber tube in a cavity having a cross-sectional width less than and a depth greater than that of a cavity of semicircular cross-section having the same cross-sectional peripheral length. It is therefore possible to mould three inner tubes 6, 7 and 8 in the same machine. The mould cavity can be W-shaped in cross-section, and it can be non-circular in plan, Figs. 6 and 7 (not shown).
[GB1443420A]
Patent IE-36981-L (IE)
Title: Hair preparation
IPC: A61K8/33
Filed: 1972-12-04
Abstract: 1406979 Hair preparations containing plasticized polymer compositions UNILEVER Ltd 4 Dec 1972 [8 Dec 1971] 56968/71 Heading C3P [Also in Divisions C4 and A5] A hair control preparation comprises a solution of a film-forming resin and a normally solid material (i.e. at 20‹ C.) which plasticizes the resin and which gradually volatilizes from the resin after application to the hair, the weight ratio of resin to volatile plasticizer being from 1 : 2 to 20 :1. The resin preferably has a Tg of at least 20‹ C. and the plasticizer, a vapour pressure at 25‹ C. and 760 mms. Hg pressure, of from 0À00001 to 2 mms. Hg. Many suitable additionpolymer resins are specified, those used in the specific examples being copoly- (vinylacetate/ vinyl pyrrolidone), copoly-(vinylacetate/crotonic acid), and acrylic ester amide copolymer containing carboxyl groups, and a methacrylic acid/methyl acrylate copolymer. Suitable plasticizers are propionamide, benzoic acid, salicylic acid, menthol, thymol, methyl-2-naphthyl ketone, hexachloroethane, benzophenone and acetamide. In the examples aerosol sprays are formed using propellants and solvents such as industrial methylated spirit and methoxyethanol. Perfumes are also included. Example 1 describes a lotion or hairspray for use in non- aerosol form.
[GB1406979A]
Patent IE-41643-L (IE)
Title: Cinnolin-3-yl carboxylic acids and derivatives
IPC: C07D237/28
Filed: 1975-07-28
Abstract: 1474399 Substituted cinnolines IMPERIAL CHEMICAL INDUSTRIES Ltd 22 July 1975 [19 Aug 1974] 36360/74 Heading C2C [Also in Division A5] Novel compounds of the Formula I wherein R stands for a hydroxy, C 1-6 -alkoxy, C 3-6 -alkoxy-alkoxy, C 4-10 -dialkylaminoalkoxy, C 7-10 - phenylalkoxy, phenoxy, amino, hydrazino, hydroxyamino, (C 1-4 - alkoxy)- carbonylmethylamino or 1,2,3,4 - tetrazol - 5- ylamino radical, and the benzene ring A optionally bears one or two substituents selected from C 1-5 -alkyl, C 5-7 -cycloalkyl, C 1-3 -alkoxy, benzyl, amino, C 1-4 -alkylamino, C 2-5 -alkanoylamino, benzyloxycarbonylamino and nitro radicals and halogen atoms, and phenyl radicals which themselves optionally bear one or two substituents selected from C 1-3 -alkoxy and nitro radicals and halogen atoms, or a pharmaceutically-acceptable salt thereof, where such can exist, but excluding cinnolin-3-yl carboxylic acid and its ethyl ester, ethyl 6- chlorocinnolin-3-yl carboxylate and ethyl 7- chlorocinnolin - 3 - yl carboxylate, and pharmaceutically-acceptable salts thereof, where such can exist, may be prepared by (1) oxidizing a compound II so as to aromatize the dihydropyradazine ring, (ii) hydrolysing a compound V wherein Cy is alkoxycarbonyl, phenylalkoxycarbonyl, phenoxycarbonyl, cyano, carbamoyl or thiocarbamoyl, in the presence of water or (iii) modifying substituent groups in the compounds I, e.g. reducing nitro groups to amino group, forming amide groups, nitrating, esterifying or N-alkylating appropriate compounds I and optionally forming pharmaceutically acceptable salts thereof where the compound is sufficiently acidic or basic. The, intermediates of the Formula II wherein COR is ethoxycarbonyl are prepared by chlorinating an ethyl 4-hydroxy-cinnolin-3-yl carboxylate to yield an ethyl 4-chloro-cinnolin-3-yl carboxylate which is reduced to the required compound. Ethyl 6 - p - chlorophenylcinnolin - 3 - yl carboxylate and ethyl 6-bromo-4-hydroxycinnolin- 3-yl carboxylate are prepared by esterification of the free acid. 6 - Bromo-, 5 - amino- and 6 - ethyl - cinnolin- 3-yl carbonyl chloride are prepared by reacting the acid with thionyl chloride. Ethyl 6 - (benzyloxycarbonylamino) - 4- hydroxycinnolin-3-yl carboxylate is prepared by hydrogenating ethyl 4-hydroxy-6-nitro-cinnolin-3-yl carboxylate followed by reaction with benzylchloroformate. Ethyl 6 - aminocinnolin - 3 - yl carboxylate is prepared by hydrogenating ethyl 6-(benzyloxycarbonylamino)-cinnolin-3-yl carboxylate. A mixture of isomers varying in the position of the methoxy radical on the phenyl substituent of ethyl 4-hydroxy 6-(methoxyphenylcinnolin- 3-yl carboxylate is prepared by reacting ethyl 6 - amino - 4 - hydroxy cinnolin - 3 - yl carboxylate with anisole in the presence of amyl nitrite.
[GB1474399A]
Patent IE-44017-L (IE)
Title: Rodenticidal composition
IPC: A01N37/34
Filed: 1976-08-10
Abstract: A group of diphenylamines, having trinitro substitution or dinitro-trifluoromethyl substitution on one ring and from 1 to 5 substituents of a defined class, particularly halogen atoms, on the other ring, are useful rodenticides.
[US4084004A]
Patent IE-781866-L (IE)
Title: Dibenzocycloheptenimines
IPC: A61K31/47
Filed: 1978-09-15
Abstract: This invention provides 5-substituted- 10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5,10-imines and their salts, methods of preparing such compounds and pharmaceutical compositions containing them. The free-base forms have the formula <IMAGE> where R is hydrogen; alkyl, alkenyl, phenylalkyl, halophenylalkyl, alkylphenylalkyl, cycloalkyl, cycloalkylalkyl or dialkylaminoalkyl, R<1> is hydrogen, alkyl, alkenyl, phenylalkyl, cycloalkyl or cycloalkylalkyl, CH2R<2> is alkyl, alkenyl, phenylalkyl, cycloalkylalkyl, dialkylaminoalkyl or hydroxyalkyl, and R<3> and R<4> are H, halogen, alkoxy, CF3S-, -CN, -COOH or -OH and are useful as antianxiety agents, muscle relaxants and in the treatment of extrapyramidal disorders such as in Parkinson's disease.
[GB2004872A]
Patent IE-881874-L (IE)
Title: Absorbent adhesive dressing
IPC: A61F13/15
Filed: 1988-06-21
Abstract: An absorbent adhesive dressing is disclosed which is intended for use in treating wounds of the ulcer and burn type where there is significant wound exudate, which has a three layer sandwich-type construction having an occlusive film (e.g. polyethylene, polypropylene etc.) as the outer layer, an absorbent layer of fibers (e.g. cellulose, synthetic fibers etc.) as the middle layer, and a wet-stick adhesive as the inner wound facing adhesive layer, wherein said adhesive layer is a continuous, substantially non-porous layer having a porosity of less than 0.5 cc/sec/in<2> which is made from an acrylic polymer having both hydrophilic and hydrophobic characteristics (e.g. a wet-stick adhesive polymer formed from emulsion polymerization in water of N-vinyl caprolactam with n-butyl acrylate or with 2-ethylhexyl acrylate, or both, and which because of the hydrophilic nature of the polymer allows exudate to pass through the adhesive layer to the absorbent fibers of its middle layer without degrading the adhesive or its performance, and where the peripheral outer edges of the layers are optionally sealed.
[EP0296787A1]
Patent IE-862047-L (IE)
Title: Homogeneous process of immunoassay using luminescence¹technique
IPC: G01N21/76
Filed: 1986-07-30
Abstract: Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium susceptible of containing it by evidencing the product obtained by the reaction between the analyte and a corresponding receiver. Said process comprises 1) the addition to said medium of a first reactant comprised of an analyte receiver; 2) the addition of a second reactant comprised of at least one of the elements of the product obtained from the reaction of the analyte with at least one of its receivers, one of the two reactants being coupled with a luminescent compound and the other reactant comprising a heavy atom or patterns containing a heavy atom; 3) the incubation of the resulting medium either after the addition of each reactant or after the addition of both reactants; 4) excitation of the resulting medium; and 5) measuring, in balance or kinetic conditions, the signal emitted by the luminescent compound, said signal being modulated by the heavy atom effect.
[WO8700927A1]
Patent IE-792495-L (IE)
Title: Combined poultry vaccine
IPC: A61K39/15
Filed: 1979-12-20
Abstract: Vaccines derived from avian reo virus to combat aberations of the skeleton such as rachitis-like symptoms, osteoperose c.q. femur degeneration, diarrhoea and growth inhibition, a process for their preparation, combined, inactivated vaccines, ready for administration and active against at least Newcastle disease and disease symptomes caused by reo virus and process for the preparation of such vaccine, are disclosed. The combined vaccine is prepared by addition of a Newcastie disease virus (NDVl) containing liquid, obtained by cultivation of a NDV, followed by inactivation of this liquid and optionally homogenizing it, together with a reo virus-containing liquid, obtained by cultivation of a rea virus, followed by inactivation of this liquid and optionally homogenizing it, to an oily phase containing as essential components at least one of the components selected from the group consisting of light paraffinic mineral oils, plant oils and pafthenic mineral oils and one or more emulsifiers, such as non-ionic surface-active compound derived from alkylene oxide and/or hexahydric alcohols and/or higher natural fatty acids such as esters or ester-ethers, optionally followed by homogenizing and/or addition of a preservative. Also a reo virus strain LZ 671, deposited with the collection D'Institut Pasteur, Paris under no. I-092 is disclosed.
[EP0013449A1]
Patent IE-44083-L (IE)
Title: Method for oxidising cinchona alkaloids.
IPC: C07D453/04
Filed: 1976-11-19
Abstract: Method of oxidizing cinchona alkaloids by reacting specific ketone with cinchona alkaloid in the presence of a strong base and aprotic solvent; following oxidation the oxo compound is reduced to the corresponding stereoisomer.
[US4093619A]
Patent IE-44403-L (IE)
Title: CIS-4a-PHENYL-ISOQUINOLINES
IPC: C07D217/02
Filed: 1976-12-14
Abstract: Cis-4a-Phenylisoquinolines The compounds of formula I, I wherein (i) R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, R3 and R4 together are oxygen, and each of R5 and R6 is hydrogen, or (ii) R1 is hydrogen, alkyl of 1 to 4 carbon atoms, or alkanoyl of 1 to 4 carbon atoms, and R2 is an alkyl group of 1 to 4 carbon atoms, and (a) either R3 and R4, together, are oxygen, or methylene, and each of R5 and R6 is hydrogen, or (b) R3 and R6, together, form a bond, and each of R4 and R5 is hydrogen, are useful as analgesics, anti-depressants, tranquilizers and sleep inducers.
[CA1085854A]
Patent IE-852913-L (IE)
Title: Purifying proteins
IPC: C07K19/00
Filed: 1985-11-20
Abstract: This invention describes a process for separating a biologically active polypeptide or protein in the form of its precursor from a mixture containing said precursor and impurities, which comprises contacting said precursor with a resin containing immobilized metal ions, said precursor comprising the biologically active polypeptide or protein covalently linked directly or indirectly to an immobilized metal ion chelating peptide, binding said precursor to said resin, and selectively eluting said precursor from said resin. Such precursor compounds are also described.
[US4569794A]
Patent NO-762661-L (NO)
Inventor: DURANT G J
IPC: C07D213/69
Filed: 1976-07-30
Abstract: FARMAKOLOGISK AKTIVE FORBINDELSER.
Patent NO-854883-L (NO)
Inventor: GREGORY WALTER ADELMAN
IPC: C07D263/20
Filed: 1985-12-04
Abstract: Novel aminomethyl oxooxazolidinyl benzene derivatives, including ( l )-N[3-[4-(1-hydroxyethyl)-phenyl]-2-oxo-5-oxazolidinylmethyl]acetamide, possess useful antibacterial activity.
Patent NO-860601-L (NO)
Inventor: NILSSON BJARNE
IPC: B01D33/06
Filed: 1986-02-18
Abstract: For adapting a disc filter element of a rotatable disc filter to varying flow conditions the fluid tight filter element body (11, 12) is provided with openings (34-39), the number of which is increased with increasing flow capacity through the filter means (17) of the filter element. Also, with increasing flow capacity the openings of the increasing number of openings are located at increasing distances from the vacuum connection (29) of the filter element. In order to prevent filtrate from entering portions of the interior of the filter element body beyond the most distant opening (39), as seen from the vacuum connection (29), such portions of the interior space of the filter element body are sealingly shut off from the remainder of the interior space.
Patent NO-864365-L (NO)
Inventor: KERB ULRICH
IPC: A61K31/58
Filed: 1986-10-31
Abstract: 1. m¢ethyl-15alpha-alkylandrosta-1,4-dienes-3,17-diones of the general formula I   see diagramm : EP0225272,P12,F1   in which R15  is an alkyl group of 1 to 4 carbon atoms, which may be substituted in the 1 and/or 2 position by a hydroxy or a C2 -C7  alkanoyloxy group or a 1,2-isopropylidenedioxy group.
Patent NO-865132-L (NO)
Inventor: ROSAMOND JAMES DONALD
IPC: C07K1/04
Filed: 1986-12-17
Abstract: Novel peptides having sulfate ester groups and containing 6 to 9 amino acids of the formula: <CHEM> possessing feeding inhibition properties and capable of stimulating the contraction of the gallbladder. Also methods of treating and preventing obesity in which these novel peptides or other specified peptides can be used and pharmaceutically acceptable salti thereof.
Patent NO-870317-L (NO)
Inventor: HOERMANN MICHAEL
IPC: E06B9/08
Filed: 1987-01-27
Abstract: A sectional overhead door which, in its longitudinal rims pointing in the direction of movement, is inwardly angled in a C-shape and stabilized at marginal zones, by reinforcing struts extending in the direction of movement of the door, with the reinforcing struts contacting the sheet-metal panel of the door leaf member extending in the plane of the door leaf member, and being in shape-mating connection in their two end zones at the front face C-shaped angled portions extending in parallel to the plane of the door leaf member. The reinforcing struts, in their contact zone against the inside of the sheet-metal panel are glued to the door leaf member and are in shape-mating connection with the rims of the C-shaped angled portions projections in end zones of the reinforcing strut extending at the front face over the rims of the C-shaped angled portions, or of the rims, engaging with practically no play in openings in the rims and, respectively, the end sections of the reinforcing strut at the front face, as viewed in the longitudinal direction of the reinforcing strut.
Patent NO-872338-L (NO)
Inventor: DIEFENBACH JEAN-JAQUES
IPC: B60C23/00
Filed: 1987-06-03
Abstract: PCT No. PCT/FR85/00276 Sec. 371 Date Apr. 14, 1987 Sec. 102(e) Date Apr. 14, 1987 PCT Filed Oct. 4, 1985 PCT Pub. No. WO87/01062 PCT Pub. Date Feb. 26, 1987.The device comprises, in a housing formed from two parts (102,103), disposed on opposite sides of a diaphragm (104), three orifices, namely an orifice (105) capable of receiving the low and high pressure and ensuring the purge, the second (107) connected to the pneumatic tire, and the third (106) of large diameter for a rapid escape, an escape valve (110) being normally closed while a passage (116) between the first and second orifices is normally closed and a passage (121) of large diameter between the second orifice and the escape valve (110) is normally open. Application in the measurement, the inflation and the deflation of vehicle pneumatic tires.
Patent NO-881702-L (NO)
Inventor: ROCKS MANFRED
IPC: H04B10/64
Filed: 1988-04-20
Abstract: The invention describes a method for optical communication of information between transmitter and receiver spatially separated from each other. The principle of heterodyne reception is utilized. A non-modulated optical carrier of a laser arranged on the receiving side is subdivided in a first fiber-optical coupler KE into two portions, the transmission path EMF and the local laser wave LL. In one branch, a displacement of frequency by the amount of  DELTA f takes place. The non-modulated optical carrier passes through a one-mode fiber EMF in direction transmitting side and is modulated there with an effective signal in a modulator MOD (FIG. 1). This now modulated optical signal travels back to the receiving side, where it is converted with the local laser wave LL into an intermediate frequency band.
Patent NO-885036-L (NO)
Inventor: WALLACH DONALD F H
IPC: C11D17/00
Filed: 1988-11-11
Abstract: Disclosed is a method of making lipid vesicles of a steroid and surfactants which do not form vesicles in the absence of the steroid. The surfactants are polyoxyethylene derivatives of 16-20 carbon ethers and amines.