baber/WOPTO huggingface dataset:
Patent WO-2020163409-A1 (WO)
Inventor: LUZZIO Michael
IPC: A61K31/439
Filed: 2020-02-04
Abstract: L'invention concerne des composés modulateurs d'épissage à petites molécules qui modulent l'épissage de l'ARNm, tel que le pré-ARNm, codé par des gènes, et des procédés d'utilisation des composés modulateurs d'épissage à petites molécules pour moduler l'épissage et traiter des maladies et des affections.
Patent WO-2020176430-A1 (WO)
Inventor: APTE RENUKA
IPC: A45D29/11
Filed: 2020-02-24
Abstract: La présente invention concerne un appareil robotique et des procédés pour une application automatique de vernis à ongles sur des ongles naturels ou artificiels ou des ongles d'orteil. Le robot utilise l'intelligence artificielle (Al) pour identifier et peindre les ongles. Le robot utilise des capteurs de profondeur et une vision artificielle pour planifier les mouvements d'un effecteur terminal. Le robot utilise des techniques d'Al et d'apprentissage automatique telles que l'apprentissage par renforcement profond, et d'autres algorithmes et calculs pour planifier sa trajectoire.
Patent WO-2020176611-A1 (WO)
Title: Pressure spike prevention in heat pump system
Inventor: CREASON MARK O
IPC: F25B30/02
Filed: 2020-02-26
Abstract: A pressure spike prevention assembly for use in a heat pump system includes a thermostatic expansion valve that includes a first port and a second port. The first port is designed to be fluidly coupled to an indoor coil, and the second port is designed to be coupled to an outdoor coil. The pressure spike prevention assembly further includes a multi-way valve that includes an inlet port, an output port, and a liquid line port. The inlet port is fluidly coupled to the first port. The output port is fluidly in communication with the second port. The liquid line port is configured to be fluidly coupled to a charge compensator of the heat pump system via a liquid line of the heat pump system.
Patent WO-2020181190-A1 (WO)
Inventor: HUNG CHENG-HUNG
IPC: G02B5/02
Filed: 2020-03-06
Abstract: L'invention concerne un substrat d'extraction de lumière (10) comportant une couche d'extraction de lumière (16). La couche d'extraction de lumière (16) comprend du bore, du borate et/ou du borosilicate ainsi que des nanoparticules (18).
Patent WO-2020190650-A1 (WO)
Title: Methods and apparatus to estimate population reach from different marginal ratings and/or unions of marginal ratings based on impression data
Inventor: SHEPPARD MICHAEL
IPC: G06F11/34
Filed: 2020-03-12
Abstract: Example methods, apparatus, and articles of manufacture are disclosed to estimate population reach. An example apparatus includes an association controller to generate a tree association corresponding to a union of a first margin of media and a second margin of the media; and one or more commercial solvers to determine first multipliers by solving first equations corresponding to panelist impressions and panelist audience totals, the second margin, or the union; perform first parallel computations with a processor to determine second multipliers to solve second equations corresponding to the tree association using the first multipliers; discard the first multipliers; perform second parallel computations to determine third multipliers by solving third equations corresponding to the tree association using database proprietor impression totals; and determine an estimate for a population reach of the media for at least one of the first margin, the second margin, or the union based on the third multipliers.
Patent WO-2020206026-A1 (WO)
Inventor: KELLY SCOTT
IPC: C07K14/725
Filed: 2020-04-01
Abstract: The present disclosure relates to the use of DNA damaging agents and leronlimab (PRO 140), or other anti-CCR5 agents, to treat or prevent cancer metastases and enhance the cell killing ability of the DNA damaging agents by selectively targeting the CCR5 receptor. The present disclosure relates to the use of DNA damaging agents and leronlimab (PRO 140), or other anti-CCR5 agents, to treat or prevent cancer metastases and reduce circulating tumor cells (CTC) or putative metastatic tumor cells in the peripheral blood following treatment,.reduce CCR5 expression on cancer-associated cells after following treatment, decrease volume in tumor size following treatment. The present disclosure may be used to treat or prevent subjects with cancer and, particularly, subjects with metastatic CCR5+ cancer.
Patent WO-2020210632-A1 (WO)
Title: Multi-valent immunotherapy composition and methods of use for treating wt1-positive cancers
Inventor: STERGIOU ANGELOS
IPC: A61P37/04
Filed: 2020-04-10
Abstract: This invention provides methods of treating, reducing the incidence of, and inducing immune responses to a WT1 -expressing cancer, by administering a combination of WT1 peptides including each of: YMFPNAPYL, RSDELVRHHNMHQRNMTKL, PGCNKRYFKLSHLQMHSRKHTG, SGQAYMFPNAPYLPSCLES, NLMNLGATL, WNLMNLG ATLKGV A A, and WNYMNLGATLKGVAA, or cytotoxic T cells induced by the combination of WT1 peptides. The combination of WT1 peptides may be administered to the subject via a WT1 delivery agent, z'.e., in peptide form, or in the form of nucleic acids encoding the WT1 peptides, or in the form of immune cells comprising nucleic acids encoding the WT1 peptides, and/or comprising or presenting the WT1 peptides. The WT1 delivery agents or CTLs can be administered to the subject in a single composition (as a heptavalent immunotherapy composition), or multiple compositions, resulting in delivery of all seven WT1 peptides and induction of an immune response against the WT1 -expressing cancer.
Patent WO-2020236938-A1 (WO)
Title: Fuel dispensing nozzle having single-handed hold open mechanism
Inventor: LUCAS DAVID
IPC: B67D7/48
Filed: 2020-05-20
Abstract: A fuel dispensing nozzle comprises a nozzle body defining a dispensing path extending between a distal inlet and a proximal outlet and configured to dispense fuel. A fuel flow valve is disposed in the nozzle body. An actuation assembly movable to open the fuel flow valve is also provided. The nozzle also includes a shut-off mechanism operatively connected to the actuation assembly. A hand lever is pivotally connected with respect to the nozzle body, the hand lever being operatively connected to the actuation assembly so as to cause opening of the fuel flow valve when the hand lever is pivoted in a valve opening direction. The hand lever has a grasping portion. The nozzle according to this aspect further includes a hold open mechanism including a trigger disposed at the proximal location of the hand lever. The trigger is pivotally connected to the hand lever and has an engaging element. A catch member is fixed with respect to the nozzle body and defines a plurality of catches, each configured to receive the engaging element of the trigger.
Patent WO-2021002999-A1 (WO)
Inventor: XIONG LI
IPC: G06F40/258
Filed: 2020-06-08
Abstract: A system for extracting a key phrase from a document includes a neural key phrase extraction model ("BLING-KPE") having a first layer to extract a word sequence from the document, a second layer to represent each word in the word sequence by ELMo embedding, position embedding, and visual features, and a third layer to concatenate the ELMo embedding, the position embedding, and the visual features to produce hybrid word embeddings. A convolutional transformer models the hybrid word embeddings to n-gram embeddings, and a feedforward layer converts the n-gram embeddings into a probability distribution over a set of n-grams and calculates a key phrase score of each n-gram. The neural key phrase extraction model is trained on annotated data based on a labeled loss function to compute cross entropy loss of the key phrase score of each n-gram as compared with a label from the annotated dataset.
Patent WO-2020252054-A1 (WO)
Title: Compositions et méthodes pour le traitement du cancer
Inventor: LERARIO ANTONIO M
IPC: A61K31/4985
Filed: 2020-06-10
Abstract: La présente invention concerne des compositions et des méthodes pour traiter des cancers. En particulier, la présente invention concerne des compositions, des systèmes et des procédés permettant d'utiliser des profils d'expression et de méthylation géniques pour la stratification et le traitement du carcinome adrénocortical et des médicaments qui ont une utilité pour les patients stratifiés par ces moyens.
Patent WO-2020263702-A1 (WO)
Inventor: VINGER FLORENCE
IPC: B65D17/347
Filed: 2020-06-19
Abstract: A reclosable can end is provided. In some embodiments, the reclosable can end comprises: a lid base that comprises a scored area; a tab that causes the scored area to at least partially separate from the lid base to expose an opening in the lid base; a closure flap, wherein the closure flap comprises: a first portion; a second portion; an opening; and a protruding portion; and a rivet that connects the tab and the closure flap to the lid base such that the tab and the closure flap are configured to rotate around the rivet, wherein the first portion of the closure flap is configured to be inserted into the opening in the lid base end when the tab and the closure flap are rotated to a position corresponding to a position of the opening in the lid base.
Patent WO-2020263909-A1 (WO)
Title: Procédés de préparation d'une séparase active
Inventor: ROSEN LAURA E
IPC: C12N5/02
Filed: 2020-06-24
Abstract: L'invention concerne des constructions polypeptidiques contenant une sécurine, par exemple une sécurine complète ou une sécurine tronquée, fusionnée à une séparase. Les constructions polypeptidiques peuvent en outre contenir des peptides de liaison, des sites de reconnaissance de protéase et des sites de reconnaissance d'unfoldase pour faciliter l'expression et/ou la purification. L'invention concerne également des procédés pour obtenir des constructions polypeptidiques présentant une activité de séparase active, ainsi que des méthodes d'identification de composés modulateurs de la séparase tels que des inhibiteurs de la séparase.
Patent WO-2021137893-A1 (WO)
Title: Method for serving parameter efficient nlp models through adaptive architectures
Inventor: TORRES TERRENCE
IPC: G06N20/00
Filed: 2020-07-01
Abstract: A machine learning system executed by a processor may generate predictions for a variety of natural language processing (NLP) tasks. The machine learning system may include a single deployment implementing a parameter efficient transfer learning architecture. The machine learning system may use adapter layers to dynamically modify a base model to generate a plurality of fine-tuned models. Each fine-tuned model may generate predictions for a specific NLP task. By transferring knowledge from the base model to each fine-tuned model, the ML system achieves a significant reduction in the number of tunable parameters required to generate a fine- tuned NLP model and decreases the fine-tuned model artifact size. Additionally, the ML system reduces training times for fine-tuned NLP models, promotes transfer learning across NLP tasks with lower labeled data volumes, and enables easier and more computationally efficient deployments for multi-task NLP.
Patent WO-2021026014-A1 (WO)
Inventor: GRUMBERG MATHIEU
IPC: B66C1/10
Filed: 2020-07-31
Abstract: A rotating suspension point assembly permits rotation and other movement of the assembly relative to the axis of an anchor to which it is attached. Such a rotating suspension point assembly comprises a base, a flanged bushing and a mating convex washer. The base has a plate and a tubular structure projecting from the plate. The flanged bushing has an internal clearance to allow misalignment of an anchor and has a flange with a concave surface. The mating convex washer is aligned with the concave surface of the flanged bushing.
Patent WO-2021030727-A1 (WO)
Inventor: VAN EYK GREGORY
IPC: A01K15/02
Filed: 2020-08-14
Abstract: The present disclosure provides a multilayered pet chew. The multilayered pet chew has a core, a first interior layer circumferentially disposed onto the core, and an exterior layer circumferentially wrapped around the first interior layer. The pet chew may further comprise one or more additional interior layers circumferentially disposed between the first interior layer and the exterior layer. Each layer of the multilayered pet chew may be distinct from other layers in at least one characteristic such as composition, formulation, color, density, texture, smoothness, brightness, hardness, roughness, etc.
Patent WO-2022046093-A1 (WO)
Title: Prompting document sharing between collaborating users
Inventor: ZOTTO RAFAEL DAL
IPC: G06N5/00
Filed: 2020-08-31
Abstract: Examples are described herein for providing document suggestions to a group of collaborating users. In various examples, based on input provided by a first user, it may be determined that the first user intends to collaborate with a second user remotely. Based on a knowledge graph that defines relationships between users, documents, and applications usable to open the documents, a document or application may be identified that is commonly associated with both the first user and the second user. A prompt to share access with the second user to the commonly associated document or a new document compatible with the commonly associated application may be provided via a computing device of the first user.
Patent WO-2021046368-A1 (WO)
Title: Methods and compounds modifying mitochondrial function
Inventor: WANG XINNAN
IPC: A61K48/00
Filed: 2020-09-04
Abstract: The invention provides methods for identifying modulators of mitochondrial function for therapeutic use in neurodegenerative disorder. The invention provides method for identifying subjects who may benefit from the therapeutic agents. Aspects of the methods include administering MIRO1 reducer to a subject having Parkinson's Disease. Also provided are companion diagnostic assays to determine if a subject is suitable for treatment with a MIRO1 reducer, and treating the subject in accordance with the results.
Patent WO-2021081346-A1 (WO)
Title: Methods for power-efficient transfer of small data in radio resource control connected lite mode
Inventor: HE LINHAI
IPC: H04W76/27
Filed: 2020-10-23
Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may transmit, to a base station during a connection establishment procedure, a UE message indicating support for a plurality of connected modes, where the plurality of connected modes includes a first connected mode. The UE may receive, based at least in part on the UE message, a configuration message from the base station configuring resources for the UE to use while operating in the first connected mode. The UE may perform a grantless communication with the base station while operating in the first connected mode and using the configured resources.
Patent WO-2021091736-A1 (WO)
Inventor: LIU YONGNING
IPC: B29C44/12
Filed: 2020-10-28
Abstract: L'invention concerne une résine époxy à base biologique obtenue à partir d'un mélange réactionnel comprenant un composant d'éther glycidylique et un composant à base biologique comprenant un acide gras et un acide de colophane, le composant d'éther glycidylique comprenant au moins deux groupes époxyde.
Patent WO-2021126452-A1 (WO)
Title: Embolic device suited for ease of delivery and placement
Inventor: HOSHINO RYAN
IPC: A61F2/01
Filed: 2020-11-19
Abstract: An embolic device and a corresponding embolic device delivery system and method. In one example, an embolic device delivery system comprises a delivery catheter, a coupler disposed inside the delivery catheter, and an embolic device that may be carried and placed by the coupler. The embolic device includes a primary winding that forms a hollow tube such that a coupler may be threaded therethrough. Further, the embolic device may include a slotted metal tube suited to be affixed to one end of the hollow tube formed by the primary winding. Additionally, the embolic device may include a retaining mechanism that includes one or more protrusions suited to engage with one or more slots of the slotted metal tube. In this manner, the retaining mechanism is affixed to the slotted metal tube and the hollow tube formed by the primary winding.
Patent WO-2021113528-A1 (WO)
Title: Modulators of programmed death-ligand-1 and/or programmed death-ligand-2
Inventor: SUTO MARK J
IPC: A61K38/05
Filed: 2020-12-03
Abstract: The present disclosure is concerned with dipeptide compounds for the treatment of various cancers such as, for example, sarcomas, carcinomas, hematological cancers, solid tumors, breast cancer, cervical cancer, gastrointestinal cancer, colorectal cancer, brain cancer, skin cancer, prostate cancer, ovarian cancer, bladder cancer, thyroid cancer, testicular cancer, pancreatic cancer, endometrial cancer, melanomas, gliomas, leukemias, lymphomas, chronic myeloproliferative disorders, myelodysplastic syndromes, myeloproliferative neoplasms, and plasma cell neoplasms (myelomas). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Patent WO-2021126765-A1 (WO)
Title: Sensor network for subsurface impact protection system
Inventor: CUNNINGHAM VINCENT
IPC: G01M5/00
Filed: 2020-12-14
Abstract: A subsurface impact protection system for protecting an underground structure is provided. The protection system includes a subsurface polymer layer above the underground structure which is configured to absorb above-ground impact force from reaching the underground structure. A sensor network is embedded in the polymer layer. The sensor network includes a plurality of sensors configured to monitor the polymer layer by generating a corresponding plurality of sensor signals of conditions near the polymer layer and transmitting the generated sensor signals to one or more external receivers, In some embodiments, the polymer layer includes a protective mesh made up of a plurality of high density polyethylene (HDPE) strands in a woven pattern. In one such embodiment, the sensors occupy gaps in the protective mesh. A method of protecting an underground structure is also provided.
Patent WO-2021127086-A1 (WO)
Title: Optical sensor with trench etched through dielectric over silicon
Inventor: SUMMERFELT SCOTT
IPC: H01L31/054
Filed: 2020-12-17
Abstract: In described examples an integrated circuit (IC) (100) has multiple layers of dielectric material (110) overlying at least a portion of a surface of a substrate (102). A trench (106) is etched through the layers of dielectric material to expose a portion the substrate to form a trench floor (105), the trench being surrounded by a trench wall formed by the layers of dielectric material. A metal perimeter band (321) surrounds the trench adjacent the trench wall, the perimeter band being embedded in one of the layers of the dielectric material.
Patent WO-2020252503-A1 (WO)
Inventor: CURTIS MICHAEL
IPC: A61C19/06
Filed: 2020-06-11
Abstract: An applicator device for the application of hydrophobic compositions to hydrophilic surfaces. An applicator device for the application of an emulsion composition to wetted teeth. An applicator tip with at least one external ridge, a plurality of internal ridges, and a plurality of internal channels between the plurality of internal ridges.
Patent WO-2021150497-A1 (WO)
Title: Applying occurrence outcomes to virtual character telematics
Inventor: RUSSO MICAH WIND
IPC: A63F13/422
Filed: 2021-01-19
Abstract: Method and system for updating a character profile of a virtual character of a telematics-based game. In some examples, a computer-implemented method includes: generating a virtual trip including one or more virtual occurrences with the associated one or more outcomes; presenting a trip success prediction, a predicted change in vehicle condition, a first user-selectable command, and a second user-selectable command to the user; upon receiving the user's selection of the first user-selectable command, updating the character profile by at least initiating the virtual trip with the virtual character; upon receiving the user's selection of the second user-selectable command: updating the one or more outcomes according to a predetermined adjustment; and updating the character profile by at least initiating the virtual trip with the virtual character based on the updated one or more outcomes.
Patent WO-2021154629-A1 (WO)
Title: Enzymes and metal-organic frameworks (mofs)
Inventor: YAGHI OMAR M
IPC: B01J31/00
Filed: 2021-01-25
Abstract: Provided are compositions that include a metal -organic framework (MOF) including a framework defining an internal volume, an enzyme disposed within the internal volume, and a surfactant. Also provided are methods of making the compositions and their use.
Patent WO-2021155010-A1 (WO)
Title: System and method for lesion monitoring
Inventor: RAJAK ALEKSANDAR
IPC: G06T7/62
Filed: 2021-01-28
Abstract: A method of lesion monitoring includes: obtaining, at a computing device, image data and depth data depicting a lesion on a patient; detecting, at the computing device, a set of anchor points in at least one of the image data and the depth data; defining a frame of reference according to the anchor points; based on the frame of reference, detecting physical characteristics of the lesion from the image data and the depth data; and presenting the physical characteristics of the lesion.
Patent WO-2021257127-A1 (WO)
Title: Synchronous discovery logs in a fabric storage system
Inventor: DHATCHINAMOORTHY RAHUL
IPC: G06F3/06
Filed: 2021-02-03
Abstract: Systems and methods for distributed storage systems using synchronous discovery logs for fabric subsystem discovery. Storage nodes may be configured with fabric services and a management service may provide synchronization of discovery logs across fabric subsystems and between peer fabric nodes. The peer fabric nodes may communicate with one another using a fabric network protocol and corresponding fabric subsystems may communicate with each peer fabric node. When a target subsystem fabric node updates its discovery log, the updated discovery log is sent to the corresponding peer fabric node. The corresponding peer fabric node sends the updated discovery log to each subsystem fabric node and to each peer fabric node for synchronization across all subsystem fabric nodes. A host may contact any subsystem fabric node for the updated discovery log.
Patent WO-2021158656-A1 (WO)
Title: Training a vehicle to accommodate a driver
Inventor: SATO JUNICHI
IPC: B60W10/06
Filed: 2021-02-03
Abstract: A system can train a vehicle electronically to accommodate a driver. The system can train the vehicle to accommodate the ability, condition, and/or personality of the driver. The system can change the controls of the vehicle, responsive to the inputs from the driver, to match with the patterns of controls resulting from a predetermined model (such as a safe-driver model). The vehicle can appear as it were driven by a safe driver. A driver with a lower driving competence may apply physical controls in a pattern that may be slow, unstable, or insufficient. The vehicle can be trained to adjust the transformation from the UI signals to the drive-by-wire signals such that the transformed signals appear to be applied by a more competent driver on the road. The transformation can improve over time with training via machine learning.
Patent WO-2021188224-A1 (WO)
Inventor: AKBARI SAMIN
IPC: A61M5/315
Filed: 2021-02-08
Abstract: La présente invention concerne une seringue avec un ensemble piston qui est conçu pour avoir une course de distribution dimensionnée pour distribuer un produit thérapeutique fluide à partir de la seringue sans distribuer d'air ni présenter d'espace libre. La seringue comprend une tige de piston ayant un élément d'arrêt qui arrête une course de distribution de la tige de piston à une distance correspondant à un niveau d'air ou d'espace libre à l'intérieur de la seringue évitant des étapes de distribution d'air supplémentaires par un fournisseur de soins de santé.