baber/WOPTO huggingface dataset:
Patent CA-2488697-A1 (CA)
Title: Regulation of gene expression using chromatin remodelling factors
Inventor: GAO MING-JUN
IPC: C07K14/415
Filed: 2003-06-06
Abstract: The invention provides a method to regulate expression of a gene of interest in a plant comprising, introducing into the plant a first nucleotide sequence comprising, the gene of interest operatively linked to a first regulatory region, and an operator sequence capable of binding a fusion protein, and a second nucleotide sequence comprising a second regulatory region in operative association with a nucleotide sequence encoding the fusion protein. The fusion protein comprising, a DNA binding protein, or a portion thereof, capable of binding the operator sequence, and a recruitment factor protein, or a portion thereof, capable of binding a chromatin remodelling protein. In this manner, expression of the second nucleotide sequence produces the fusion protein that regulates expression of the gene of interest.
Patent CA-2489308-A1 (CA)
Title: Use of taurine for the treatment of alopecia
Inventor: DURANTON ALBERT
IPC: A23L1/30
Filed: 2003-06-23
Abstract: The invention relates to the use of taurine and/or hypotaurine and/or the acceptable salts thereof in an oral composition for the preparation of an oral composition that can be used for the treatment and prevention of ageing of the pilosebaceous unit and/or alopecia.
Patent CA-2490905-A1 (CA)
Inventor: GRUNEWALD MARCUS
IPC: A47J37/10
Filed: 2002-12-20
Abstract: The invention relates to a cooking utensil, in particular for frying or cooking food without fat. Said utensil comprises a base (1) and a wall (2), said base (1) having a raised section (3) for supporting the food, in additi on to a largely annular depression (4) surrounding the raised section (3). The kitchen utensil minimises the time the frying fat and other liquid, emanatin g from the food, remain on the raised section and facilitates cleaning, as the raised section (3) is convex or curved in such a way that the frying fat or other liquid can flow into the depression (4).
Patent CA-2492826-A1 (CA)
Inventor: LIPOWSKY GERAD
IPC: A61P33/06
Filed: 2002-09-16
Abstract: The invention relates to the finding that virus like particles (VLPs) can be loaded with immunostimulatory substances, in particular with DNA  oligonucleotides containing non-methylated C and G (CpGs). Such CpG- VLPs are dramatically more immunogenic than their CpG-free counterparts and induce enhanced B and T cell responses. The immune response against antigens optionally coupled, fused or attached otherwise to the VLPs is similarly enhanced as the immune response against the VLP itself. In addition, the T  cell responses against both the VLPs and antigens are especially directed to the Thl type. Antigens attached to CpG-loaded VLPs may therefore be ....sim.  ideal vaccines for prophylactic or therapeutic vaccination against allergies, tumors and other self-molecules and chronic viral diseases.
Patent CA-2493221-A1 (CA)
Title: Polyethylene glycol aldehyde derivatives
Inventor: WON CHEE-YOUB
IPC: C07C47/198
Filed: 2003-07-16
Abstract: Polyethylene glycol aldehyde compounds are provided. Processes of making and using such compounds, as well as chemical intermediates are also provided.
Patent CA-2493498-A1 (CA)
Title: Stump cutting device with load-distributing tooth sockets
Inventor: SHINN RICKY D
IPC: A01G23/06
Filed: 2005-01-20
Abstract: A cutting device includes a rotatable base defining a plurality of closed-sided, tooth sockets. A plurality of tooth assemblies are mounted within respective sockets. Each tooth assembly includes a tooth holder having a base-engaging portion adapted to fit into the socket, and a cutting tip projecting from the rotatable base for engaging and cutting an object.
Patent CA-2497754-A1 (CA)
Inventor: NIEN MING
IPC: B23D23/00
Filed: 2005-02-18
Abstract: A blind cutter includes at least a worktable, a drive device, and a number of knife modules. The drive device has a speed-reducing motor for rotating a rotary shaft, and a number of gears fixed on the rotary shaft to engage and move a number of racks. The knife modules respectively have a module base arranged lengthwise on the work table, having a special hole for special blinds to pass through, with a knife fitted in slidably and respectively moved by the racks for cutting a blind material respectively extending on the module bases.
Patent CA-2498279-A1 (CA)
Inventor: AASEN ERIC J
IPC: B65D75/00
Filed: 2002-10-31
Abstract: A stand-up reclosable package is formed with a top and bottom seal, and a length-wise seal. The end of the bag is gusseted to form a flat, square shap ed surface for the package to stand up. Another seal is formed length-wise alon g one side of the package to form the sides of the pack, defining the interior volume of the package. The top of the bag may be sealed in a manner consiste nt with existing vertical form fill and seal technology. The top of the package may have a reclosable feature. Additionally, the present invention provides a method of forming said reclosable stand-up package, including filling the package with desired contents as the package is formed and sealed.
Patent CA-2498680-A1 (CA)
Title: Inductor assembly for a product conveyance system
Inventor: HORN RODNEY S
IPC: A01C7/20
Filed: 2005-02-28
Abstract: An inductor assembly includes an inlet configured to receive a forced air stream in a path to engage a flow of product so as to generate a combined stream of forced air and product for conveyance to a remote receiver or planting unit for application in an agricultural field. A series of inductor segments each defines a first and a second conduit to communicate the combined stream of forced air and product from the inductor housing to the remote receiver for application in a field. Each first and second conduit includes a bypass opening located to receive a bypass portion of the forced air stream in a manner that enhances the flow of the combined stream of forced air and product to the remote receiver. A vane is located to enhance guidance of the forced air stream in a path toward the mass of product received in the inductor housing.
Patent CA-2500916-A1 (CA)
Title: Substitute for animal protein in cattle feed
Inventor: RODEE WILLIAM LESLIE
IPC: A23K50/15
Filed: 2002-10-08
Abstract: A combination one or more species of lactobacillus bacteria and one or more types of fibrolytic enzymes can be used to replace animal protein in cattle feed. The combination results in a better amino acid balance in the digestive tract of cattle resulting in a better utilization of nitrogen. Less water-soluble nitrogen compounds pass through the digestive tract resulting in less pollution. More nitrogen in the feed is converted to water insoluble compounds resulting in better feed utilization and less water-soluble pollution in the manure. The diseases carried by some animal protein additives, such as "mad cow" are not present in the additives of the present invention.
Patent CA-2503394-A1 (CA)
Title: Temperature limited heaters for heating subsurface formations or wellbores
Inventor: CARL FREDERICK GORDON JR
IPC: E21B36/04
Filed: 2003-10-24
Abstract: A method described includes applying an alternating electrical current to one or more electrical conductors (112). The electrical conductors may be located in a subsurface or a subsurface wellbore. The electrical conductors may provide an electrically resistive heat output upon application of the alternating electrical current. At least one of the electrical conductors may include an electrically resistive ferromagnetic material. The electrically resistive ferromagnetic material may provide a reduced amount of heat above or near a selected temperature. Heat may be allowed to transfer from the electrically resistive ferromagnetic material to a part of the subsurface or the subsurface wellbore.
Patent CA-2505432-A1 (CA)
Inventor: PERRY DARRYL
IPC: E04H12/22
Filed: 2005-04-27
Abstract: A pair of brackets are provided for supporting threaded rods alongside a foundation post on a footing block of a static structure, for example a residential deck. The brackets, which permit mounting of the threaded members alongside the post instead of beneath the post, permit the rods to be mounted to an existing structure without replacement of existing posts or footing blocks. Rotation of the threaded members acts to adjust longitudinal position of the members relative to the posts for effectively extending the length of the posts and adjusting the height thereof when levelling the structure.
Patent CA-2505960-A1 (CA)
Title: Miter saw with angle adjustment
Inventor: BERGMANN LAURENTIUS
IPC: B23Q16/06
Filed: 2005-05-02
Abstract: A miter saw with angular adjustment has a carrier (1), a turntable (3) which is able to turn relative to the carrier (1) and which forms a workpiece support surface (2), and a turntable fixing device (8) for fixing the turntable (3) relative to the carrier (1) in certain reproducible angular positions. The miter saw turntable fixing device (8) enables adjustment of the angular position relative to the carrier in a manner which is continuous and mechanically reproducible.
Patent CA-2508246-A1 (CA)
Title: Multiple stapling device for narrow blood vessels
Inventor: RICHARD THIERRY
IPC: A61F2/06
Filed: 2003-12-16
Abstract: A multiple stapling device (100) for stapling a graft (110) to a vessel (111).  The device (100) includes a body (102) having a plurality of staple channels (132) housing straight wire segments (134) extending therethrough. A plurality of staple drivers (138), one in each of the staple channels (132) is adatped to push the straight wire segments (134) to form ring-shaped staples (158) piercing the graft (110) and the vessel (111). The multiple stapling device (100) may also include one or more bolsters (142, 144) filling the annular space created by the ring-shaped staples (158). One such bolster (142) may be formed or otherwise connected to, the prosthesis (110).
Patent CA-2510466-A1 (CA)
Title: Vacuum packaging machine for product packages with multiple products
Inventor: STEVENS DAVID
IPC: B65B31/02
Filed: 2003-12-22
Abstract: A vacuum packaging machine (141) and a conveyor (17) to deliver a product package from an upstream station (40) to a position adjacent a vacuum chamber (3a). The conveyor (17) has a longitudinal direction defined by the direction of travel of the product package. The vacuum chamber has a heat sealing and cutting assembly (143) oriented transversely to the longitudinal direction of the conveyor and in a position with sufficient spacing between end walls of the vacuum chamber and the assembly (143) for the product package containing two or more products to be loaded into the vacuum chamber (3a) with at least one product located in front of the heat sealing and cutting assembly and at least one other product located behind the heat sealing and cutting assembly.  The heat sealing and cutting assembly (143) seals and cuts between two products to form two separate evacuated packages.
Patent CA-2514552-A1 (CA)
Title: Adjuvant used in dielectric heating-assisted cancer treatment, and cancer treatment method
Inventor: IMAGAWA TAKASHI
IPC: A61P35/00
Filed: 2004-01-30
Abstract: There is provided an adjuvant capable of enlarging an ablation area and reducing ablation unevenness in a dielectric heating-assisted cancer treatment such as radiofrequency ablation used for treatment of hepatic cancer. The adjuvant includes a conductive substance such as a metal element (e. g.,iron) and a pharmaceutically acceptable carrier of lipid dispersion, polymer solution or polymer dispersion.
Patent CA-2515152-A1 (CA)
Title: Ear flaps for helmets
Inventor: WHELEN GARTH W
IPC: A42B3/30
Filed: 2002-11-27
Abstract: Eear flap/warmers (1) found in sporting helmets (2) allow the wearer to connect to and utilize external audio (stereo) reproduction and/or 2-way communication devices with added convenience over previous inventions by incorporating a mechanical electrical interconnect (12) located in or by replacing, the helmet chinstrap connection. The user can conveniently don or remove said EAR FLAPS (1) equipped helmet by disconnecting and reconnecting said interconnect. Added convenience to EAR FLAPS (1) can be providedby use of multifunct ional chinstrap connection mechanical electrical interconnects (1 2) providing the benefits of the electrical interconnect (12) with the functioning to secure the sporting helmet (2) chinstraps (10). Where applicable said multifunctional chinstrap connection can also incorporate a built in microphone and (where applicable and not installed in said ear flap/warmers) circuitry, resistors and/or switches to allow the function of audio reproduction and 2-way communication through the same EAR FLAPS (1) equipped helmet(2).
Patent CA-2515509-A1 (CA)
Title: Cast iron semi-finished product excellent in workability and method of production of the same
Inventor: YAMAMURA HIDEAKI
IPC: C22C37/08
Filed: 2004-02-10
Abstract: The present invention provides tough cast iron and cast iron semi-finished products excellent in workability without heat treatment requiring massive heat energy and long time and a method of production enabling these to be efficiently produced, that is, cast iron of ingredients of white cast iron where particles of spheroidal graphite or flattened graphite are dispersed, cast iron where the ingredients of the white cast iron satisfy, by wt%, (%C)<=4.3-(%Si)÷3 and C>=1.7% and where the particles of spheroidal graphite are dispersed at a density of 50 particles/mm2 or more, or cast iron where the particles of flattened graphite have a width of 0.4 mm or less and a length of 50 mm or less.
Patent CA-2515519-A1 (CA)
Title: Medical use of ras antagonists for the treatment of capillary malformation
Inventor: BOON LAURENCE
IPC: C12Q1/68
Filed: 2003-03-20
Abstract: The invention relates to the field of vascular anomalies and methods for diagnosing and treating them. The invention provides for the causative gene (RASA1) and mutations therein which are useful for diagnosing inherited capillary malformations. The invention further provides RASA1 antagonists for use in treatment of capillary malformations.
Patent CA-2515544-A1 (CA)
Title: Compounds for the treatment of viral infection
Inventor: BOMAN ERIK
IPC: C07D311/76
Filed: 2004-02-06
Abstract: The present invention is related to compounds, their intermediates, processes for their preparation and use, and pharmaceutical compositions comprising the compounds. The novel compounds are useful in therapy, and in particular for the treatment of viral infection, particularly HIV infection.
Patent CA-2516770-A1 (CA)
Inventor: LAURIDSEN KIRSTEN
IPC: A23L27/30
Filed: 2004-02-25
Abstract: The invention relates to the use of polydextrose for the sweetening of edible products. The invention relates especially to the use of polydextrose for synergistically enhancing the sweetness of sweet tasting sugar compounds selected from sucrose, fructose, glucose, lactose, maltose, maltulose, isomaltulose, galactose and mixtures or syrups thereof. The invention provides edible products having a desired level of sweetness with a reduced level of sugar or an enhanced level of sweetness without increased level of sugar. The invention also relates to a process for sweetening an edible product with polydextrose.
Patent CA-2516777-A1 (CA)
Title: Human cyclooxygenase-3 enzyme and uses thereof
Inventor: CODD ELLEN E
IPC: C12N9/02
Filed: 2004-02-20
Abstract: The present invention provides nucleic acid and polypeptide sequences describing a neve isozyme of the cyclooxygenase enzyme, herein named as human cyclooxygenase 3. The isolated nucleic acid or polypeptide molecule of the invention can be used in detection assays, gene therapy, and screening assays.
Patent CA-2519470-A1 (CA)
Title: Pattern bonded nonwoven fabrics
Inventor: RUDISILL EDGAR N
IPC: D04H3/14
Filed: 2004-03-18
Abstract: A pattern bonded nonwoven fabric comprising a nonwoven fiber web having a geometrically repeating and visually discernable base pattern of bond points having at least one shape with at least one area defined by the shape and a second visually distinguishable bond pattern incorporated within said base pattern.
Patent CA-2521129-A1 (CA)
Title: Pyrimidinone compounds as calcilytics
Inventor: LUENGO JUAN
IPC: A61K31/505
Filed: 2004-04-07
Abstract: The pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.
Patent CA-2521453-A1 (CA)
Inventor: BUVAT PIERRICK
IPC: C08L83/16
Filed: 2004-11-10
Abstract: Polymère modifié, empoisonné, de type poly(éthynylène phénylène éthynylène silylène) susceptible d'être obtenu par addition sélective d'un composé à unique fonction réactive sur les liaisons acétyléniques d'un polymère de poly(éthynylène phénylène éthynylène silylène). Compositions contenant ces polymères modifiés. Procédé de préparation de ces polymères modifiés. Nouvea ux polymères de type poly(éthynylène-phénylène-éthynylène-silylène) auto- empoisonnés. Produits durcis susceptibles d'être obtenus par traitement thermique desdits polymères modifiés ou auto-empoisonnés. Les polymères et produits durcis présentent des propriétés mécaniques améliorées tout en conservant d'excellentes propriétés thermiques.
Patent CA-2522126-A1 (CA)
Title: A synergistic pharmaceutical combination comprising cicletanine for the prevention or treatment of diabetes
Inventor: EGRI JANOS
IPC: A61P3/10
Filed: 2004-04-14
Abstract: The invention refers to a synergistic pharmaceutical combination which comprises (a) a first pharmaceutical composition containing cicletanine or a pharmaceutically suitable acid addition salt thereof and one or more conventional carrier(s), and (b) a second pharmaceutical composition containing an antidiabetic or anti-hyperlipidemic active agent or, if desired and chemically possible, a pharmaceutically suitable acid addition salt or a salt formed with a pharmaceutically suitable base thereof and one or more conventional carrier(s). The pharmaceutical combination is suitable for the prevention or treatment of, among others, diabetes mellitus.
Patent CA-2523922-A1 (CA)
Title: Azaindole compounds as kinase inhibitors
Inventor: HANSEN PETER
IPC: A61P29/00
Filed: 2004-05-06
Abstract: The present invention relates to novel azaindole compounds which are kinase inhibitors, methods for their preparation intermediates and pharmaceutical compositions comprising them.
Patent CA-2527705-A1 (CA)
Title: Electrolyte material for fuel cell
Inventor: HASE KOHEI
IPC: H01M8/02
Filed: 2005-01-18
Abstract: An electrolyte material for a fuel cell which has a proton-conducting system composed of at least (a) a Br.phi.nsted acid and (b) a base having an unshared electron pair, wherein the base (b) has one or more groups introduced to a group having the unshared electron pair and the sum of the numbers of the constituting atoms except H atoms contained in all the groups introduced is three or less. The above electrolyte material exhibits high proton conductivity in an unmoisturized or water-free state.
Patent CA-2527734-A1 (CA)
Inventor: CREEL HARDIE D
IPC: F02B33/18
Filed: 2004-05-19
Abstract: An apparatus and method to enhance the overall performance of engines in one or more of the following ways: by increasing the power output; by reducing the level of unwanted atmospheric emissions; and by reducing engine wear. The apparatus is an engine (e.g., 2-stroke or 4-stroke, diesel or gasoline-fueled internal combustion engine) comprising a crankshaft, crankcase, combustion chamber, oil pan, piston, connecting rod, intake port, exhaust port, and scavenging pump assembly having an air cylinder and an air diaphragm. The scavenging pump assembly allows for the control of air and fuel intake port pressure by controllably boosting an intake mixture into the combustion chamber, while minimizing the potential for engine lubricating-oil to combine with the intake air-fuel mixture.
Patent CA-2529309-A1 (CA)
Title: Viral polymerase and modulation thereof
Inventor: KUIPER MIKE
IPC: C07K14/02
Filed: 2004-06-11
Abstract: The present invention provides the tertiary structure of a Hepatitis B Virus (HBV) polymerase reverse transcriptase (rt) domain from which a variant HBV  polymerase mutations associated with resistance to or having reduced sensitivity to an anti-viral drug have been mapped. The present invention further provides methods of identifying, designing and/or modifying agents capable of modulating the functional activity of the HBV polymerase based on the atomic co-ordinates provided by the tertiary structure. The present invention still further provides a method of modulating HBV polymerase functional activity and agents useful for same. The agents identified in accordance with the method of the present invention are particularly useful inter alia in the treatment and/or prophylaxis of infection by an HBV  resistant to or exhibiting reduced sensitivity to an anti-viral drug. The agents may also have utility as diagnostic agents such as to distinguish between resistance mutations. Furthermore, the present invention enables responses of particular potential anti-viral drugs to be predicted. In addition, new targets within the polymerase have been identified.
Patent CA-2529456-A1 (CA)
Title: Crystalline mesoporous oxide based materials useful for the fixation and controlled release of drugs
Inventor: KREMER SEBASTIEN PHILIPPE BRIG
IPC: A61K9/51
Filed: 2004-06-28
Abstract: The invention describes a new class of crystalline silica material having two levels or porosity and structural order. At the first level, building units are nanoslabs of uniform size having zeolite framework. At the second structural level, nanoslabs are assembled, e.g. linked through their corners, edges or faces following patterns imposed by interaction with cationic surfactant or triblock copolymer molecules. After evacuation of these molecules, microporosity is obtained inside the nanoslabs, and a precise mesoporosity between the nanoslabs depending on the tiling pattern of the zeolite nanoslabs, as evidenced by X-ray diffraction. These materials are useful for the fixation of biologically active species, such as poorly soluble drugs.
Patent CA-2530025-A1 (CA)
Title: 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
Inventor: KAUFMAN MILDRED L
IPC: C07D401/00
Filed: 2004-06-25
Abstract: Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and/or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer~s disease, muscular dystrophies, cognitive impairment, decreased libido, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.
Patent CA-2530476-A1 (CA)
Title: System and method of investing funds
Inventor: FIELD ASHWIN
IPC: G06Q40/06
Filed: 2004-06-28
Abstract: In one aspect, the invention provides a data communications network including communication devices enabling communication between a user and a funds investment system, a method of investing funds with asset manager programs by distributing total funds available for investment to a plurality of asset manager programs said distribution effected by performing the method step of performing a plurality of intermediate allocations, each intermediate allocation according with predefined rules supplied to the system by the user over the communications network and repeating the step of performing intermediate allocations until all available funds are allocated with asset manager programs.