baber/WOPTO huggingface dataset:
Patent JP-2021013786-A (JP)
Title: Game machine
Inventor: WATANABE KAZUTERU
IPC: A63F7/02
Filed: 2020-11-10
Abstract: To provide a game machine capable of enhancing player's motivation to play a game by increasing a degree of attention to the game and interest in the game.SOLUTION: A game machine 10 can set a jackpot probability in which a jackpot lottery results in a jackpot from among a plurality of mutually different jackpot probabilities, and can display the set jackpot probability (game setting value) on a 7-segment display part 39. Display contents regarding a jackpot probability on the 7-segment display part 39 are controlled according to the number of game balls (the number of special out balls) entering a special out ball port 373 from beginning of a jackpot game to initial winning or an opening/closing execution mode to completion of the opening/closing execution mode.SELECTED DRAWING: Figure 39
Patent JP-2021045558-A (JP)
Title: Method of making vascular model
Inventor: IFAT LAVI
IPC: A61B6/03
Filed: 2020-11-13
Abstract: To provide a method for vascular assessment.SOLUTION: The method comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce 1910 a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method further comprises obtaining 1915 a flow characteristic of the stenotic model, and calculating 1930 an index indicative of a vascular function, based at least in part on the flow characteristic in the stenotic model.SELECTED DRAWING: Figure 9
Patent JP-2022081326-A (JP)
Title: Rotary electric machine and driving device
Inventor: TSUJIMOTO KENTO
IPC: H02K9/19
Filed: 2020-11-19
Abstract: To provide a rotary electric machine having a structure capable of improving a cooling efficiency of a coil end.SOLUTION: An rotary electric machine 10 includes: a rotor; a stator; and a supply port supplying a coolant to the stator, and comprises: a refrigerant supply part 50 positioned at an upper side in a vertical direction of the stator; and a first guide wall part 24 positioned at the upper side in the vertical direction of the stator. The first guide wall part includes: a first opposite surface 24a arranged oppositely to the upper side in the vertical direction of the coil end; and a first bent curving surface 24b bent from the first opposite surface. The supply port contains a first supply port 54 supplying the coolant to the coil end. The first supply port contains a first opposite port 57a opening toward the first opposite surface. The bent curving surface is bent to an outer side in a radial direction from an end part on the side far from the first opposite port of the first opposite surface in view of an axial direction of a center shaft. A boundary between the first opposite surface and the first bent curving surface is overlapped with the coil end at the outer side in the radial direction from an inner edge of the coil end in view of the vertical direction.SELECTED DRAWING: Figure 4
Patent JP-2022085081-A (JP)
Title: Induction heating cooker
Inventor: SHIMIZU JUNICHI
IPC: H05B6/12
Filed: 2020-11-27
Abstract: To provide an induction heating cooker capable of notifying a customer of the product life according to an installation period rather than a usage period of actual cooking even for a product that does not have a clock function by operating the control unit such as a microcomputer even when the product power is turned off.SOLUTION: An induction heating cooker includes heating means, a top plate arranged above the heating means, and a display unit arranged in front of the top plate, and further includes a frequency detection unit connected in parallel with the power supply circuit connected downstream of a rectifier circuit that rectifies an AC power supply, and a control unit that measures an energization time on the basis of a signal from the frequency detection unit and notifies the display unit when the energization time exceeds a predetermined time.SELECTED DRAWING: Figure 2
Patent JP-2022086271-A (JP)
Title: Power storage device
Inventor: MAEHARA YUKI
IPC: H01G11/12
Filed: 2020-11-30
Abstract: To provide a power storage device that can suppress the misalignment of a storage cell.SOLUTION: In a power storage device 1A, each of current collectors 21 constituting a positive electrode 11 and a negative electrode 12 includes a first region 21c provided with a positive electrode active material layer 22 and a negative electrode active material layer 23, and a second region 21d located at the peripheral edge of the current collector 21. A distance D1 in the stacking direction between the current collectors 21 in the second region 21d is smaller than a distance D2 in the stacking direction between the current collectors 21 in the first region 21c. A spacer 14 includes a sealing portion 15 that is located between the second regions 21d of the current collector 21 of the positive electrode 11 and the negative electrode 12, and is bonded to the current collector 21 of the positive electrode 11 and the negative electrode 12 in the second region 21d, an overhanging portion 16 projecting outward from the outer edge 21e of the current collector 21 of the positive electrode 11 and the negative electrode 12 when viewed from the stacking direction, and a connecting portion 17 connecting the adjacent overhanging portions 16 in the stacking direction.SELECTED DRAWING: Figure 2
Patent JP-2022086675-A (JP)
Title: Protection circuit
Inventor: FURO NAOKI
IPC: H02H11/00
Filed: 2020-11-30
Abstract: To provide a novel, improved protection circuit that can suppress a failure in a switching element even if the protection circuit is reversely connected to a power source and a ground by mistake, for example.SOLUTION: One example of the protection circuit includes a switching element formed using a field effect transistor that switches between electric connection and disconnection between a power source terminal and a load terminal in accordance with control voltage applied from a control circuit to a gate, and a first protection element that electrically disconnects between a ground terminal and the gate when a first potential difference between the potential of the ground terminal and the potential of the power source terminal is less than a threshold, and electrically connects between the ground terminal and the gate when the first potential difference is more than or equal to the threshold.SELECTED DRAWING: Figure 2
Patent JP-2021091674-A (JP)
Title: Oil-based solid cosmetics
Inventor: MARUKI KO
IPC: A61K8/891
Filed: 2020-12-01
Abstract: To provide oil-based solid cosmetics that are excellent in shape retention and loosening feel, and excellent in mat finish and cosmetic durability.SOLUTION: Oil-based solid cosmetics contains following components (A)-(D): (A) wax 10-30 mass%, (B) at least one inhibitor for crystallization of the component (A) that is selected from the group consisting of talc, boron nitride, dextrin fatty acid ester, sucrose fatty acid ester, and ethyl cellulose, (C) oil solution with an IOB value of less than 0.16, and (D) oil solution with an IOB value of 0.16 or more, the oil-based solid cosmetics having a hardness of 40-350 gf at 25°C.
Patent JP-2022088126-A (JP)
Title: Valve device
Inventor: YOSHIOKA DAIKI
IPC: F16K27/02
Filed: 2020-12-02
Abstract: To provide a valve device capable of reducing a use amount of a brazing material while securing sealability.SOLUTION: A solenoid valve 1A comprises a valve seat member 4 separate from a valve body 2, and an annular recess 243 is formed on a detached side surface 241 of the valve body 2. This makes it easier to fasten a molten brazing material to the recess 243, and an amount of a brazing material required can be reduced as compared with the configuration in which the brazing material permeates the entire circumference between the entire outer peripheral surface of a flange part and the inner peripheral surface of the valve body 2. Therefore, it is possible to reduce an amount of the brazing material used while securing sealability.SELECTED DRAWING: Figure 2
Patent JP-2021035999-A (JP)
Title: Macrophages eating cancer cells using their own calreticulin as guide
Inventor: IRVING L WEISSMAN
IPC: A61P37/04
Filed: 2020-12-02
Abstract: SOLUTION: Therapeutic and diagnostic methods are provided, where the methods relate to induction of expression of calreticulin on phagocytic cells. Specifically, the methods relate to macrophage-mediated programmed cell removal (PrCR), the methods comprising either: increasing PrCR by contacting a phagocytic cell with a toll-like receptor (TLR) agonist; or down-regulating PrCR by contacting a phagocytic cell with Bruton's tyrosine kinase (BTK). In some embodiments, an activator of TLR signaling or a BTK agonist is provided in combination with CD47 blockade.SELECTED DRAWING: Figure 1
Patent JP-2022088837-A (JP)
Title: Tag writing device, label printer and information processing program
Inventor: KAWASAKI YUKI
IPC: G06K17/00
Filed: 2020-12-03
Abstract: To appropriately determine a relative positional relation between an optimum radio tag and an antenna.SOLUTION: According to an embodiment, a tag writing device includes a conveyance part, an antenna, an acquisition part, a determination part, a selection part and a decision part. The acquisition part acquires reception intensity about a plurality of radio tags multiple times each time a mount is conveyed by a fixed amount while the conveyance part conveys the mount from a start position to an end position. The determination part determines an intermediate position between the start position and the end position as a position at which the sum of reception intensities acquired while the mount is conveyed from the start position to the intermediate position and the sum of reception intensities acquired while the mount is conveyed from the intermediate position to the end position are closest. The selection part selects a radio tag in which an intermediate position is determined as a position within a prediction range as an object tag. The decision part decides a relative positional relation between the radio tag and the antenna in performing writing on the basis of the reception intensities of the radio signal transmitted from the object tag.SELECTED DRAWING: Figure 3
Patent JP-2022090503-A (JP)
Title: Motorcycle
Inventor: TAMURA HIROSHI
IPC: B62J17/00
Filed: 2020-12-07
Abstract: To provide a motorcycle capable of improving visibility effect.SOLUTION: A motorcycle includes: a headlight 40 for illuminating a forward road surface of a vehicle body; an auxiliary light 56 detachably installed on the vehicle body; and a front cowl 38 for covering the front of the vehicle body. The auxiliary light 56 is positioned so that an upper end thereof is higher than a lower end of the headlight 40 and is outside the front cowl 38.SELECTED DRAWING: Figure 2
Patent JP-2022092827-A (JP)
Title: Computer system and data processing method
Inventor: KO SHIMEI
IPC: G06N20/00
Filed: 2020-12-11
Abstract: To predict a first motion time of a specific wave through use of time-series data.SOLUTION: A computer system manages model information for defining a U-Net configured to execute, on time-series data, an encoding operation using downsampling blocks and a decoding operation using upsampling blocks, executes the encoding operation and the decoding operation on the input time-series data by using the model information. The downsampling blocks and the upsampling blocks each include a residual block. The residual block includes a time axis direction attention block which calculates a time axis direction attention for emphasizing a specific time domain in a feature map. The time axis direction attention block includes an arithmetic operation for calculating attentions different in time width, and calculates a feature map to which the time axis direction attention is added by using the attentions.SELECTED DRAWING: Figure 5
Patent JP-2022095346-A (JP)
Title: Loosening stopper for drum head
Inventor: HOSOKAWA YOSHIHISA
IPC: G10D13/02
Filed: 2020-12-16
Abstract: To provide a loosening stopper for a drum head that can prevent a lag bolt from loosening at a low cost with a simple configuration, is adaptive to a drum differing in distance between a corner head part of the lag bolt and a side wall part of a hoop, and can minimize area in contact with the hoop to suppress the lag bolt from rotating in a loosening direction with strong force while suppressing an influence on acoustic performance.SOLUTION: A loosening stopper for a drum head is formed of a flexible plate body 21 made of resin. The plate body 21 comprises a mount part 23 which has a rotation stop hole 22 formed to be pressed in a corner head part 8a of a lag bolt 8, a linear abutting part 24 which is made to abut on a corner part 4d where a side wall part 4b and a flange part 4c of a hoop 4 connect, and a flection part 25 between the abutting part 24 and the mount part 23. When the rotation stop hole 22 is pressed against the corner head part 8a of the lag bolt 8 to be disabled to rotate so that the abutting part 24 abuts on the corner part 4d, the flection part 25 flexes and the abutting part 24 is pressed against the corner part 4d with the restoring force thereof.SELECTED DRAWING: Figure 4
Patent JP-2022096679-A (JP)
Title: Exterior structure and wire harness
Inventor: KINOSHITA KOSUKE
IPC: H02G3/04
Filed: 2020-12-18
Abstract: To provide an exterior structure and a wire harness that can properly route electric wires.SOLUTION: A wire harness WH1 includes a plurality of electric wires W and an exterior structure 1, which exterior packaging the plurality of electric wires W. The exterior structure 1 includes a pair of a flat exterior members 10 that are formed in a flat plate shape and sandwich the plurality of electric wires W, and a holding sheet 20 which is formed in a sheet shape and is provided over the pair of flat exterior members 10 to regulate the falling off of the plurality of electric wires W sandwiched between the pair of flat exterior members 10, and a restraining portion 30 that bundles and restrains a part of the plurality of electric wires W sandwiched between the flat exterior members 10. As a result, the exterior structure and the wire harness have the effect that the electric wires can be properly routed.SELECTED DRAWING: Figure 3
Patent JP-2022096780-A (JP)
Title: Skin moisture transpiration inhibitor and method for manufacturing the same
Inventor: LU YI
IPC: A61K8/98
Filed: 2020-12-18
Abstract: To provide new applications for a component derived from a sea cucumber.SOLUTION: A skin moisture transpiration inhibitor uses the protease decomposition product of a sea cucumber as an active ingredient. The protease decomposition product of a sea cucumber is a soluble component and includes a material having an absorbance in a wavelength of 215 nm. The proportion of the material having a molecular weight of 100,000 or less is 35% or more.EFFECT: A transepidermal water loss (TEWL) is suppressed more than the case of not ingesting the skin moisture transpiration inhibitor by orally ingesting the skin moisture transpiration inhibitor, and the skin barrier function of an ingestion person is improved.SELECTED DRAWING: None
Patent JP-2021054407-A (JP)
Title: Float aggregate coupling floats for solar panel and installation method for the float aggregate
Inventor: NIIMI TAKAYA
IPC: B63B35/38
Filed: 2020-12-23
Abstract: To provide a float aggregate capable of reducing trouble of maintenance and inspection, etc., by shortening a cable to be laid.SOLUTION: A float aggregate with coupled floats for solar panels comprises: a pier having a linear float part where the floats are mutually coupled linearly; an aggregating float part formed of the mutually coupled floats so as to have the solar panels arranged; and a coupling float part formed of the mutually coupled floats so as to couple the aggregating float unit and the pier. The coupling float part has a number of floats in the width direction that is more than a number of floats in the width direction of the pier, and less than a number of the floats in a side of the aggregating float part coupled with the coupling float part.SELECTED DRAWING: Figure 1
Patent JP-2022099422-A (JP)
Title: Vehicle recognition device and vehicle control device
Inventor: KIMATA AKIHITO
IPC: G08G1/015
Filed: 2020-12-23
Abstract: To provide a vehicle recognition device which can calculate a vehicle length of the other vehicle located around an own vehicle.SOLUTION: A vehicle recognition device 200 includes a camera which images the other vehicle around an own vehicle, a wheel estimation part 542 which estimates a tire dimension on the basis of an image of a license plate arranged on a surface of the other vehicle and having a known dimension and an image of the tire of the other vehicle included in images imaged by the camera, and a length calculation part 543 which calculates a length of the other vehicle on the basis of an image of a side surface of the other vehicle included in the images imaged by the camera and the tire dimension estimated by the wheel estimation part 542.SELECTED DRAWING: Figure 4
Patent JP-2022102416-A (JP)
Title: Coating composition, coating layer, article having coating layer, and method for producing article having coating layer
Inventor: TANAKA KOJI
IPC: B05D5/00
Filed: 2020-12-25
Abstract: To provide a coating composition used to form an antiviral coating layer, an antiviral coating layer, an article having an antiviral coating layer, and a method for producing an article having an antiviral coating layer.SOLUTION: The present invention discloses a coating composition used to form an antiviral coating layer, the coating composition containing a polyester resin (A) and a β-hydroxyalkylamide compound (B).SELECTED DRAWING: None
Patent JP-2022102711-A (JP)
Title: Notification device and notification method
Inventor: KATAOKA TOMOHARU
IPC: G06T7/00
Filed: 2020-12-25
Abstract: To provide a notification device and a notification method, capable of performing proper notification to a passenger.SOLUTION: A notification device according to one aspect of an embodiment includes an acquisition unit and a notification unit. The acquisition unit acquires a captured image captured by a camera provided in an entrance of a vehicle. The notification unit, when a passenger of the vehicle is included in the captured image acquired by the acquisition unit, provides the passenger with a predetermined notification. The notification unit, after providing the notification, changes a form of the notification for the passenger when the captured image acquired by the acquisition unit includes the same passenger as the passenger provided with the notification.SELECTED DRAWING: Figure 1
Patent JP-2022102814-A (JP)
Title: PDE5 inhibitor
Inventor: SAITO SHIHO
IPC: A61K36/752
Filed: 2020-12-25
Abstract: To provide a new substance having a PDE5 inhibitory effect.SOLUTION: The PDE5 inhibitor includes a Citrus sudachi pericarp extract.SELECTED DRAWING: None
Patent JP-2022104848-A (JP)
Title: Respiration circuit holding device for respirator
Inventor: UMAKI YOSHIFUMI
IPC: A61M16/08
Filed: 2020-12-30
Abstract: To provide a respiration circuit holding device for a respirator, which prevents an artificial nose coming-off accident.SOLUTION: A respiration circuit holding device 1 for a respirator comprises a first holding part, a second holding part, and connection parts 4a and 4b for connecting first and second holding parts together. The connection parts 4a and 4b can arbitrarily change a separation distance between the first and second holding parts. The first holding part is attached to an upstream-side respiration circuit of an artificial nose 20, and the second holding part is attached to a downstream-side respiration circuit of the artificial nose 20.SELECTED DRAWING: Figure 1
Patent JP-2020515999-A (JP)
Title: 古典的なコンピュータ上で量子回路をシミュレートする方法
IPC: G06F30/32
Filed: 2018-03-19
Abstract: 【課題】等価なメモリ容量でより多くの量子ビット、または、より合理的なメモリ容量で同じ数の量子ビットのいずれかを説明することができる量子回路シミュレーションが必要である。【解決手段】半導体集積回路を含むコンピュータ処理ユニット上で、量子回路モデルの操作をシミュレートする方法であって、量子回路を、ｎ量子ビットが連続的に一緒に横断されるように意図されたｄ個の隣接する層Ｌｋに分割し、各層が単一の量子ゲートＧｋを含む操作と、３つの予め定義されたタイプの量子ゲートの中から、回路の各量子ゲートＧｋにタイプを割り当てる操作と、を含んでおり、上記３つの予め定義されたタイプは、伝達行列が対角である対角型ゲートと、伝達行列が非対角であり、０または１の値を有する演算子を含み、行ごとおよび列ごとに１つの演算子しかない従来型ゲートと、対角型でも従来型でもない高密度型ゲートと、である。
Patent JP-2020528640-A (JP)
Title: リチウム二次電池用非水電解液及びこれを含むリチウム二次電池
IPC: H01M10/052
Filed: 2018-11-22
Abstract: 本発明は、リチウム塩、カーボネート系溶媒及びプロピルプロピオネートを含む非水系溶媒、及び化学式１で表される化合物を含むリチウム二次電池用非水電解液、及びこれを備えたリチウム二次電池に関する。
Patent JP-2020531548-A (JP)
Title: 共開始剤を支持する粒子状担体を含む歯科用組成物
IPC: A61K6/62
Filed: 2018-08-29
Abstract: 本発明は、担体の表面に共有結合した共開始剤を支持する粒子状担体を含む光開始剤系を含む、歯科用組成物に関する。更に、本発明は、歯科用組成物中での粒子状担体の使用に関する。粒子状担体は、１つ以上の重合性二重結合を有するモノマー、オリゴマー、および／またはポリマーを架橋するための、複数の共有結合した三級アミノ基および／または三級ホスフィン基を表面上に提示する。
Patent JP-2020535779-A (JP)
Title: 制御器およびこれを含むモータ組立体
IPC: H02M7/48
Filed: 2018-07-27
Abstract: 実施例は基板；前記基板上に配置される制御器ハウジング；前記基板と前記制御器ハウジングの間に配置されるＣＭフィルタ部；前記ＣＭフィルタ部の下部に配置されるＤＭフィルタ部；前記基板と前記ＤＭフィルタ部間に配置される制御器カバー；前記基板と前記制御器カバーの間に配置されるパワーモジュール部；および前記基板と結合するコネクタ部を含み、前記パワーモジュール部はパワーモジュール；および前記パワーモジュールを囲むモールド部を含む制御器およびこれを含むモータ組立体に関する。これに伴い、パワーモジュール部の発熱問題を解決することができる。【選択図】図２
Patent JP-2020536169-A (JP)
Title: ステンレス鋼、ステンレス鋼をアトマイズすることにより得られるプレアロイ粉及びプレアロイ粉の使用
IPC: B22F3/16
Filed: 2018-10-04
Abstract: 本発明はステンレス鋼に関する。ステンレス鋼は、重量％（ｗｔ．％）で、Ｃ ０．３２〜０．５０、Ｓｉ ０．１〜１．０、Ｍｎ ０．１〜０．８、Ｃｒ １１〜１４、Ｍｏ １．８〜２．６、Ｖ ０．３５〜０．７０、Ｎ ０．０５〜０．１９、任意の元素、残部Ｆｅ及び不純物から構成される。
Patent JP-2021505101-A (JP)
Title: ストリッピングププライヤ
IPC: B26B27/00
Filed: 2018-11-08
Abstract: 本発明は２つのクランプ顎１９，２０と、２つの内側切断顎２２、２３と、２つのハンドル部４、５とを有するストリッピングプライヤ１に関し、ハンドル部４、５を一緒に押す過程で、切断顎２２、２３が引きロッド３０によって引きロッド３０に作用するバネ３９の力に抗して開始位置から終了位置まで変位可能である。引きロッド３０はスロット３４内で移動可能な引きピン３３により移動させられる。この種のストリッピングプライヤが取扱いにおいて有利な方式でさらに改善されるように構成するために、引きロッド３０がそのハンドル側端部にて、ハンドル側取付部から引きロッド３０を解放するために引きロッド３０に固定されかつ引きロッド３０に対するバネ３９の力に抗して変位可能な変位部品を有する。
Patent JP-2021500129-A (JP)
Title: カテーテルアセンブリ
IPC: A61F2/966
Filed: 2018-09-28
Abstract: カテーテルアセンブリの実施形態が開示される。カテーテルアセンブリは、シャフトと、少なくとも1つのコネクタアセンブリとを備える。コネクタアセンブリは、第1のコネクタ部分および第2のコネクタ部分を備えることが可能であり、第1のコネクタ部分は、シャフトの遠位端部に対して固定的に結合され、第2のコネクタ部分上の少なくとも1つのスロット内に保持された少なくとも1つの径方向延在ピンにより、限定された移動自由度を有しつつ第2のコネクタ部分に対して結合される。少なくとも1つのスロットは、シャフトの長手方向軸を中心とする第1のコネクタ部分に対する第2のコネクタ部分の限定された回転を可能にする過大周方向寸法を有し得る。
Patent JP-2020531046-A (JP)
Title: 遺伝子操作された免疫刺激性細菌菌株およびその使用
IPC: A61K35/745
Filed: 2018-07-11
Abstract: 免疫刺激性細菌および細菌を含む医薬組成物が提供される。本明細書において提供される免疫刺激性細菌は、免疫刺激性細菌の抗腫瘍活性を強化する１つまたは複数のモダリティを含む。免疫刺激性細菌の中でも、アデノシン栄養要求性となるようにまたはアデノシン栄養要求性であるように、および／または遺伝子遮断、および／またはＴＲＥＸ１、ＶＩＳＴＡ、ＰＤ−Ｌ１等の免疫チェックポイントの発現を媒介する、ｓｈＲＮＡおよびマイクロＲＮＡ等のＲＮＡｉをコードするプラスミド、および免疫系に影響を与える遺伝子を含むように改変されたサルモネラ属菌種等の細菌が提供される。細菌は、その抗腫瘍活性を強化するような追加の改変を含む。また、医薬組成物を投与することによって、成長を阻害するかまたは固形腫瘍の容量を減少させる方法が提供される。
Patent JP-2021502745-A (JP)
Title: ブロックチェーン上に検証鍵を記録するためのシステム
IPC: H04L9/32
Filed: 2018-10-29
Abstract: 本明細書で説明されるシステム及び方法は、ブロックチェーンシステムにおけるロッキングトランザクションの実行に関する。スマートコントラクトのコンテキストでは、作業者によって公開される回路の正しい実行のプルーフの公的記録（例えばブロックチェーンに記録される）と検証鍵を有することが有利であり、それによって、誰か（例えばブロックチェーンのノード）が計算とプルーフの有効性を確かめることを可能にする。しかしながら、ブロックチェーン上にデータの大きなブロック（例えば複数の楕円曲線点を含み得る大きな鍵）を記録することには課題がある。例えばビットコインベースのブロックチェーンネットワークでは、標準トランザクションを利用するプロトコルは、全体として第１の所定サイズ制限よりも大きくないロッキングスクリプト及びアンロッキングスクリプトに制約されることがあり、リディームスクリプト（利用される場合）のサイズは、第２の所定サイズ制限よりも大きくないように制限されることがある。
Patent JP-2021502972-A (JP)
Title: 癌のポジオチニブ治療に対する反応を示すバイオマーカー
IPC: C12Q1/6886
Filed: 2018-11-14
Abstract: 癌において、ポジオチニブ治療に対する敏感性または抵抗性を示すバイオマーカー及びその使用方法を提供する。
Patent JP-2021505579-A (JP)
Title: 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターを作成するためのプロセス
IPC: C07D401/14
Filed: 2018-12-07
Abstract: 本開示は、式（Ｉ）の化合物を調製するための方法を提供する。一部の実施形態では、式Ｉの化合物は、以下の構造を有するＮ−（１，３−ジメチルピラゾール−４−イル）スルホニル−６−［３−（３，３，３−トリフルオロ−２，２−ジメチル−プロポキシ）ピラゾール−１−イル］−２−［（４Ｓ）−２，２，４−トリメチルピロリジン−１−イル］ピリジン−３−カルボキサミド（化合物１）である。一部の実施形態では、式（Ｉ）の化合物は、以下の構造を有するＮ−（ベンゼンスルホニル）−６−［３−［２−［１−（トリフルオロメチル）シクロプロピル］エトキシ］ピラゾール−１−イル］−２−［（４（Ｓ））−２，２，４−トリメチルピロリジン−１−イル］ピリジン−３−カルボキサミド（化合物２）である。
Patent JP-2021506765-A (JP)
Title: Ｄｕｘ４の発現に関連する疾患の治療のための化合物
IPC: A61K31/4439
Filed: 2018-12-13
Abstract: 本発明は筋ジストロフィー等のＤＵＸ４の発現に関連する疾患の治療のための化合物に関する。本発明はまた、該化合物の使用、又は該化合物の使用の方法に関する。【選択図】 なし