Patent SG-11201807252Q-A (SG)
Title: Anti-lag-3 antibodies
Inventor: WANG CHENG-I
IPC: C07K16/28
Filed: 2017-03-03
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 111111110111101110101011111 HO 111110111010rn 1111101011111001111101111 MI International Bureau ... .... ..Yjd (10) International Publication Number (43) International Publication Date ..... ...,/ WO 2017/149143 Al 8 September 2017 (08.09.2017) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C07K 16/28 (2006.01) kind AO, of national protection available): AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/EP2017/055060 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, 3 March 2017 (03.03.2017) KP, MD, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language: English RU, TH, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 10201601719R 4 March 2016 (04.03.2016) SG (84) Designated States (unless otherwise indicated, for every (71) Applicant: AGENCY FOR SCIENCE, TECHNOLOGY kind AND RESEARCH [SG/SG]; 1 Fusionopolis Way #20-10, GM, Connexis, 138632 (SG). TZ, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (71) Applicant (for LS only): CLEGG, Richard Ian [GB/GB]; TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, City Tower, 40 Basinghall Street, London Greater London DK, EC2V 5DE (GB). LV, SM, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (72) Inventors: WANG, Cheng-I; c/o Agency for Science, GW, KM, ML, MR, NE, SN, TD, TG). — Technology and Research, 8A Biomedical Grove 03-00, Declarations under Rule 4.17: 138648 (SG). OH, Hsueh Ling Janice; c/o Agency for — — — Science Technology and Research, 8A Biomedical Grove — of inventorship (Rule 4.17(iv)) 03-00, 138648 (SG). YEO, Siok Ping; c/o Agency for Sci- Published: ence, Technology and Research, 8A Biomedical Grove 03- = 00, 138648 (SG). LEE, Chia Yin; c/o Agency for Science — with international search report (Art. 21(3)) Technology and Research, 8A Biomedical Grove 03-00, before the expiration of the time limit for amending the 138648 (SG). claims and to be republished in the event of receipt of = = (74) Agents: CLEGG, Richard et al.; Mewburn Ellis LLP, amendments (Rule 48.2(h)) City Tower, 40 Basinghall Street, London Greater London _ with sequence listing part of description (Rule 5.2(a)) EC2V 5DE (GB). = = = = = = = = Il M 7r 11 C:r 7r 11 IN 11 © \" (54) Title: ANTI-LAG-3 ANTIBODIES C ) .,.. (57) : Anti-LAG-3antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.