baber/WOPTO huggingface dataset:
Patent JP-2001511160-A (JP)
IPC: A61K31/455
Filed: 1998-02-02
Abstract: A pressure-liquefied propellant mixture for aerosols, comprising a fluorinated alkane, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, and carbon dioxide, makes possible an improvement of the wetting properties of pharmaceutically active compounds, with which the formulation problems existing with hydrofluoroalkanes in relation to suspension as well as solution aerosols can be overcome and thus improved medicinal aerosol formulations can be obtained. With the aid of carbon dioxide, it is also possible to specifically influence the pressure and thus the particle size distribution and also by displacement of oxygen from the hydrofluoroalkanes to improve the storage stability of oxidation-sensitive active compounds.
Patent JP-2001506226-A (JP)
Title: シナプシンのモジュレーションによるアルツハイマー病の治療法
IPC: A61P25/28
Filed: 1996-05-13
Abstract: (57)【要約】
培養した海馬ニューロンのシナプス接合部の再生及び維持の双方におけるシナプシンＩＩの役割は、シナプスの破壊に関係する神経変性疾患、特にアルツハイマー病の治療の根拠である。ニューロンでのシナプシンＩＩ発現がアンチセンスシナプシンＩＩオリゴヌクレオチドによって阻止される場合、シナプスを再生及び維持する海馬ニューロンの能力は致命的に破壊される。軸索形成後であるがシナプス形成直前にシナプシンＩＩをアンチセンス抑制するとシナプス形成が妨げられる。シナプス形成後にシナプシンＩＩを抑制すると大部分の既存のシナプスが破壊される。アンチセンスオリゴヌクレオチドを除去した後に達成されたシナプシン欠乏ニューロンでのシナプシンＩＩの再発現は、シナプス接合部の再確立をもたらし、シナプシンＩＩがシナプスの維持及び／又は回復に必要であることが証明される。従って、シナプシンｃＤＮＡ又はタンパク質を患者の神経系に送達することを含むシナプスの再生及び維持に基づく治療方法、移植する細胞のシナプス形成能を促進するためのシナプシンｃＤＮＡの使用、及び内在性シナプシンの発現を増強する薬剤、その活性を高める薬剤、又はその活性に似せる薬剤の使用は、神経変性疾患を治療することができる。
Patent JP-2000512912-A (JP)
Title: 改良されたヴァイア加工速度を有するレーザ装置
IPC: B23K26/06
Filed: 1997-11-20
Abstract: (57)【要約】
レーザヴァイア穿孔システム及びその作業方法は、増大したパルス繰返し率で作用するが、充分なエネルギー及び一貫したパルス間エネルギーの出力パルスを提供する。基板の中にヴァイアホールを穿孔するためには、調波生成のためのLBO結晶を用いて、パルス化レーザビームが形成される。レーザビームは、基板のアブレーションしきい値よりも大きいエネルギー密度を有する。パルス化レーザビームを用いてヴァイアホールが形成される。パルス化レーザビームのエネルギー密度は、第１のエネルギー密度よりも小さく基板のアブレーションしきい値よりも小さいエネルギー密度まで減少させられる。パルス化レーザビームは、形成されるべき次のヴァイアの部位に再位置づけされる。パルス化レーザビームのエネルギー密度は、当初のエネルギー密度まで再び増加され、次のヴァイアホールが形成される。パルス化レーザビームのエネルギー密度は、ビームのパルス繰返し率を増大させることによって減少させられる。同様にして、パルス化レーザビームのエネルギー密度は、ビームのパルス繰返し率を減少させることによって増大させられる。
Patent JP-H10506684-A (JP)
IPC: C25D1/10
Filed: 1997-04-01
Abstract: The titanium anode container (56) of electroplating apparatus is cube shaped, with its rear wall parallel to or against the container (50) wall. A titanium spacer maintains a set gap between the rear and leading anode container walls. The carrier surface can be adjusted in relation to the surface of the anode container. The electroplating apparatus has a container (50) for the electrolyte (58), with at least one wall angled against the vertical. The titanium anode container (56) is filled with an anode material. An outlet surface (89) for ions is on the surface of the carrier (87) acting as the cathode, where they are deposited, facing the anode container (56). The anode container (56) is cube shaped, with its rear wall parallel to or against the container (50) wall. A titanium spacer maintains a set gap between the rear and leading anode container walls. The carrier surface can be adjusted in relation to the surface of the anode container.
Patent JP-2000508210-A (JP)
IPC: A61F11/00
Filed: 1997-04-17
Abstract: An auditive prosthesis, including a cochlear implantable electrode-set applied on a carrier. The electrode-set provides electrical currents for stimulating auditory nerves in the modiolus. The electrode-set having a first series of electrode-poles arranged beside each other and at a predetermined distance of each other along a first longitudinal side of the carrier. Each of the electrode-poles of the first set are individually connected with a signal-generator. The signal-generator is a second electrode-pole connected with a signal-generator. The second electrode-pole is arranged along a second longitudinal side of the carrier and extending over substantially the same distance as the first electrode-poles. The signal-generator is provided for generating signals between selected electrode-poles, electrical field-lines with radial and/or longitudinal components.
Patent JP-2000510451-A (JP)
IPC: A61P3/00
Filed: 1997-04-10
Abstract: The invention relates to the use of growth hormone, preferably human growth hormone or analogues thereof for the manufacturing of a medicament for treatment of individuals with the Metabolic syndrome. They include individuals with abdominal/visceral obesity and its metabolic and circulatory consequences including insulin resistance, lipoprotein aberrations and hypertension. The medicament is also used to increase insulin sensitivity and for treatment and prevention of non-insulin dependent diabetes mellitus.
Patent JP-2000516643-A (JP)
Title: アスコルビン酸化合物を含む組成物
IPC: A61K8/891
Filed: 1998-05-07
Abstract: (57)【要約】
アスコルビン酸化合物、結晶性無機鉱物クレー、解凝剤、親水性液体キャリヤを含む組成物が開示される。
Patent JP-2001514606-A (JP)
IPC: B31D5/00
Filed: 1998-03-13
Abstract: There is provided an inflatable cushion filling machine for forming inflated packaging cushions from a roll of tubular thermoplastic material. The machine includes a film supply section and a cushion forming section. The cushion forming section includes means for delivering the tubular material through the cushion forming section; means for applying tension to the web of tubular material while air is being introduced into the tubular material. Means are provided for introducing air into the area between the tension means to fill the cushion. When filled, a sealing band, displaced transversely across the inflated tubular thermoplastic material, seals the lower end to form the top of one cushion and the bottom of the next cushion. Prior to forming the cushion, the walls of the tubular material separate from each other by the residual air from the filling operation of the previous cushion. A perforation knife may be provided to separate each cushion from the next succeeding cushion.
Patent JP-2000510340-A (JP)
Title: 集合分泌抗体を発現するトランスジェニック植物
IPC: C12N15/82
Filed: 1997-05-05
Abstract: (57)【要約】
本発明は植物中の異種多量体タンパク質、例えば、抗体の発現及び集合、並びにこのようなタンパク質を発現するトランスジェニック植物に関する。幾つかの好ましい実施態様の一つにおいて、植物中の機能性分泌抗体の発生及び集合が開示される。又、本発明は本発明のトランスジェニック植物により生産された組成物及びその組成物の使用方法を開示する。
Patent JP-2001517942-A (JP)
Title: ヒト腫瘍抑制遺伝子
IPC: C07K16/18
Filed: 1998-03-20
Abstract: (57)【要約】
本発明はヒト腫瘍抑制遺伝子（ＴＵＰＲＯ−２）及びＴＵＰＲＯ−２を同定し、コード化するポリヌクレオチドを提供する。また本発明は発現ベクタ及び宿主細胞、アゴニスト、抗体或いはアンタゴニストも提供する。本発明はＴＵＰＲＯ−２の発現に関連する疾患を治療するための方法を提供する。
Patent JP-2000511265-A (JP)
Title: 可調節固定伸長部材
IPC: F16B7/14
Filed: 1997-05-22
Abstract: (57)【要約】
この発明は、梯子を含む種々の器具に適用される可調節固定伸長部材を提供するものである。好ましい形態では、２つの部材（１、２）が摺動接触状態で含まれ、一方の部材（２）がテーパー状又は傾斜面部を有する。これらの部材は、締め付け部（３）及びそれと隣接した部材（２）に挿通され、楔又はカム部材が上記締め付け部（３）を調節して該締め付け部を介してテーパー状部材の通過を制限するのに使用される。
Patent JP-2000512748-A (JP)
IPC: G01N33/50
Filed: 1997-05-23
Abstract: A sterile aqueous specimen collection fluid containing a buffer, an aliphatic aldehyde at a concentration of 0.15M to 3.4M, and one or more heavy metal salts at a concentration of 0.2x10-3M to 0.2M, and having a pH of 6.8 to 8.0. Also disclosed is a method of colleting a specimen with such a fluid for haematological analysis.
Patent JP-2001521426-A (JP)
IPC: A61C17/34
Filed: 1998-03-10
Abstract: The invention is directed to a brush section (1) for an electric toothbrush. The brush section (1) has a mounting tube (2) in which is accommodated an actuatable plug-on shaft (3) mounted for rotation about a longitudinal axis (4), said shaft being equipped with a driving element (24) arranged eccentrically to the longitudinal axis (4). Further, the brush section (1) has a bristle carrier (8) mounted for rotation about a transverse axis (10) and equipped with a driven element (22) arranged eccentrically to the transverse axis (10) and coupled with the driving element (24). In this arrangement, a rotary movement (5) of the plug-on shaft (3) about the longitudinal axis (4) produces a rotary movement (25) of the bristle carrier (8) about the transverse axis (10. The plug-on shaft (3) and the bristle carrier (8) are braced against each other and/or against the mounting tube (2) by spring means. This prevents the occurrence of rattling noises in activated condition of the electric toothbrush.
Patent JP-2000510486-A (JP)
Title: α−トコフェロール−４−アミノ安息香酸エステル化合物及びその製造方法
IPC: A61K31/353
Filed: 1998-04-28
Abstract: (57)【要約】
化学式（Ｉ）で示されるα−トコフェロール−4−アミノ安息香酸塩化合物は、α−トコフェロールと4−アミノ安息香酸のエステル化によって製造される。これらのエステルは、生体内で構成化合物に転換され、そのため、赤血球の形成及び代謝の促進、成長刺激因子の役割、皮膚の健康維持、毛髪脱色の防止のような、4−アミノ安息香酸の臨床的及び生物学的効果と同様に、酸化防止のような、α−トコフェロールの生物学的効果を有する。前記化学式（Ｉ）において、R 1 及びR 2 は、同じでも異なっていてもよく、各々は水素原子又は直鎖若しくはC 1 −C 4 アルキル鎖である。
Patent JP-2001524975-A (JP)
IPC: A61K8/73
Filed: 1998-05-02
Abstract: The invention relates to skin care products comprising 0.01-1.0 weight percent chitosan in form of a dissolved salt and 10-500 ppm zinc in the form of a dissolved salt contained in an aqueous carrier which preferably also contains surfactants, soluble thickening agents, emulsified oil components or a mixture thereof. Said skin care products have a soothing effect on irritated skin and can be used for the prevention of acne. Preferably, salts of hydroxycarboxylic acids, such as chitosan glycolate and zinc gluconate, are used.
Patent JP-2001527598-A (JP)
IPC: G03F1/68
Filed: 1998-05-15
Abstract: A hot melt ink having a water auto-dispersibility of at least 50%, methods for using this ink to provide marks having a water auto-dispersibility of at least 50%, and methods for using this ink to provide UV opaque masks are disclosed.
Patent MX-148875-A (MX)
Inventor: BRUNDIN JAN-OLOF
IPC: A61B17/42
Filed: 1980-05-06
Abstract: PCT No. PCT/SE80/00130 Sec. 371 Date Jan. 4, 1981 Sec. 102(e) Date Dec. 23, 1980 PCT Filed May 5, 1980 PCT Pub. No. WO80/02369 PCT Pub. Date Nov. 13, 1980.A device for temporarily or permanently closing body passages or cavities in humans and animals and including a member (2) of a material which swells at least 20% by absorbing body fluids and which is substantially inert to body fluids and surrounding tissues, the member (2) being dimensioned so as to be able to be introduced with clearance into the passage or cavity in its unswollen state but to take up the whole cross-section of the passage or cavity in the swollen state and then to be held by pressure against the surrounding walls of the passage or cavity. The device also comprises an element (7) with outer portions (8) which, in the unswollen state of the member, project out from its surface and which are made of a material with such suitable stiffness that the element with said outer portions (8) spreads out, in a yielding manner, towards the surrounding walls of the passage or cavity in such a manner that the element tends to lock the member in its inserted position by pressure against the wall, which ensures holding of the member before it has developed any direct pressure against the surrounding wall through its swelling.
Patent MX-159763-A (MX)
Inventor: SU KAI CHIANG
IPC: B29D11/02
Filed: 1982-08-10
Abstract: Contact lenses comprising polymeric lens materials are coloured by reactive dyestuffs covalently bonded to monomer units of the polymer backbone, said dyestuffs being reactive dyes capable of forming ether linkages with cellulose, and being reactive with hydroxyl, amino, amido or mercapto groups present in a hydrogel polymer to form the covalent bond therewith. The invention is of particular interest in the area of "soft" contact lenses (hydrogel lenses).
Patent MX-161820-A (MX)
Inventor: THOENEN ALAN
IPC: A47C23/053
Filed: 1984-09-18
Abstract: The spring core for a mattress consists of several, identically formed spring coils arranged in side by side rows with each row forming a wire piece having an upper and a lower mutually aligned end spiral in a U-shape, and having opposite legs joined together by a base webb. Adjacent coil springs are joined together at their end spirals along abutting legs by helical connecting springs. To arrange the springs at tight angles in rows and columns, a length of one leg is greater than the length of another leg and all the coil springs are oriented in the same direction, except along a edge region of the spring core.
Patent NZ-195377-A (NZ)
Title: Lipid vesicles for transporting medicinal agents
Inventor: BALDESCHWIELER J D
IPC: A61K9/50
Filed: 1980-10-28
Abstract: Lipid vesicles comprise a lipid bilayer which includes an analog of a cell-surface receptor such as dicetyl phosphate, stearylamine, 6-(5-cholesten-3β-yloxy)hexyl 1-thio-β-L-fucopyranoside, 6-(5-cholesten-3β-yloxy)hexyl 1-thio-β-D-galactopyranoside, 6-(5-cholesten- 3β-yloxy)hexyl 1-thio-a- D-mannopyranoside, 6-(5-cholesten- 3-yloxy)hexyl 2-acetamido-3-deoxy- 1-thio-β-D-galactopyranoside, 6-(5-cholesten- 3β-yloxy)hexyl 6-amino-6-deoxy-1-thio- β-D-galactopyranoside or 6-(5-cholesten- 3p-yloxy)hexyl 6-amino-6-deoxy-1- thio-a-D-mannopyranoside, together with cholesterol, distearoyl phospatidylcholine and an effective amount of a physiologically compatible radioactive tracer or a cytotoxic or therapeutic agent as a part of the vesicles. The vesicles of this invention can be administered to mammalian, including human, hosts and have been found to release the contents of the vesicles in a predetermined manner, and in some cases to be rapidly concentrated in the lymphatic system and<sub>/</sub>or liver, lungs, or spleen of the host.
Patent NZ-206996-A (NZ)
Title: Skin or hair-care compositions containing a silanised adsorbent
Inventor: FAIRHURST E
IPC: A61K8/34
Filed: 1984-01-31
Abstract: Silanised adsorbents may be used to alleviate seborrheic conditions by draining sebum from the stratum corneum.
Patent NZ-213524-A (NZ)
Title: Herbicidal compositions containing thiolcarbamate herbicides and carbamate or thiolcarbamate extenders
Inventor: PALLOS F M
IPC: A01N47/10
Filed: 1985-09-18
Abstract: Herbicidally active thiolcarbamates are employed in combination with a certain thiolcarbamate, thionocarbamate, thiolcarbamate sulfone, thiolcarbamate sulfoxide, dithiocarbamate or carbamate extender compound, the latter in sufficient quantity to minimize soil degradation and to prolong the soil life of the former. As a result, the herbicidal effectiveness of the thiolcarbamate herbicide is significantly enhanced and prolonged, rendering a single application or multiple applications of the herbicide effective over a longer period of time. Such herbicidal compositions can optionally contain a non-phytotoxic antidotally effective amount of thiolcarbamate herbicide antidote.
Patent NZ-214026-A (NZ)
Title: Cleaning/disinfecting process and composition containing interhalogens
Inventor: CORBY M P
IPC: A01N59/00
Filed: 1985-10-31
Abstract: A composition characterised in that it comprises one or more interhalogens or sources thereof and one or more acids or sources thereof which are not appreciably oxidised by the interhalogen(s) is disclosed.When diluted with water to in-use solution strength, such may be used in an ambient cleaning and/ordisinfecting process in accordance with the present invention particularly for milk-or food-handling equipment.
Patent NZ-215470-A (NZ)
Title: 4-nitro-1-phenylpyrazoles and herbicidal and insecticidal compositions
Inventor: GEHRING R
IPC: C07D231/16
Filed: 1986-03-13
Abstract: Herbicidally and insecticidally active 4-nitro-1-phenylpyrazoles of the formula   <IMAGE>   in which R1 and R2 each independently is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl or halogenoalkyl, R3, R4, R5, R6 and R7 each independently is hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, or -(X)n-R8, X is oxygen, sulphur, sulphinyl or sulphonyl, n is 0 or 1, and R8 is halogenoalkyl.
Patent NZ-224028-A (NZ)
Title: Bovine growth hormone analogue compositions and animals
Inventor: ASTON ROGER
IPC: C07K19/00
Filed: 1988-03-25
Abstract: A peptide having primary structural homology to a continuous sequence of amino acid residues of growth hormone in the region spanning positions 35 to 53 or antigenically equivalent peptides thereto or salts thereof, may be used in an antigenic formulation to potentate the effects of growth hormone in a vertebrate.
Patent NZ-227666-A (NZ)
Title: Aromatic esters and thioesters and pharmaceutical and cosmetic compositions
Inventor: SHROOT BRAHAM
IPC: C07C235/42
Filed: 1989-01-19
Abstract: Aromatic esters and thioesters have the formula   <IMAGE> (I) wherein X represents oxygen or sulfur, R1 represents -CH2OH, -CH(OH)-CH3, -COOR5 or  <IMAGE>  R5 represents hydrogen, lower alkyl, lower alkenyl, monohydroxyalkyl or polyhydroxyalkyl, r' and r'' represent hydrogen, lower alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl optionally substituted, the residue of an amino acid or aminated sugar, or taken together form a heterocycle, R2represents alpha , alpha '-disubstituted alkyl having 4-12 carbon atoms or mono- or polycyclic cycloalkyl having 5-12 carbon atoms whose carbon linking carbon is trisubstituted, R3represents hydrogen, lower alkyl, or -Si(CH3)2R'3 wherein R'3 represents lower alkyl, and R4 represents hydrogen or lower alkyl, and the salts of these aromatic esters and thioesters of formula (I) when R5 represents hydrogen. These aromatic esters and thioesters can be used in human and veterinary medicine and in cosmetic formulations.
Patent NZ-232968-A (NZ)
Title: Syringe assembly with needle shield having tamper evidence features
Inventor: SWEENEY NIALL
IPC: A61M5/50
Filed: 1990-03-19
Abstract: A syringe having tamper evidence features includes a barrel (21) having a chamber (22) for retaining fluid, an open proximal end (23), and a distal end (25) having a passageway (27) therethrough in fluid communication with the chamber (22). A needle shield (32) having a longitudinal axis (33), a distal end (34) and an open proximal end (35) slidably engages the distal end of the barrel covering the passageway. The shield (32) includes an outwardly projecting shield lug (37) having a cam surface (38). A collar (40) having an annular side wall (41), an open proximal end (43) and a distal end (44) having an aperture (45) therethrough, is adjacent to the distal end of the barrel with the needle shield projecting distally through the aperture. The aperture is sized so that the proximal end of the needle shield cannot pass therethrough. The collar includes an inwardly projecting lug (46) having a follower surface (47) for contacting the cam surface (38). The cam surface and the follower surface being configured so that rotational force applied to the needle shield around the longitudinal axis causes the cam surface to contact the follower surface to apply a force to the follower surface. Securement means (49) is provided for releasably holding the collar adjacent to the barrel. The securement means is positioned so that the force applied to the follower surface can disengage the securement means allowing the collar to move and allowing the needle shield to be removed from the barrel.
Patent NZ-235906-A (NZ)
Title: Milk and eggs containing antibodies to honey allergens.
Inventor: STOLLE RALPH J
IPC: A23L15/00
Filed: 1990-10-31
Abstract: Anti-honey food products are disclosed, such food products being obtained from animals hyperimmunized against at least one antigen found in honey, and preferably whole unfractionated honey. A vaccine producing said anti-honey food product is disclosed, said vaccine comprising at least one honey antigen and preferably whole unfractionated honey. Further, a dietary supplement for humans and especially infants which protects against harmful allergens and microorganisms found in honey is disclosed, said supplement comprising the anti-honey eggs or milk or fractions thereof.
Patent NZ-237275-A (NZ)
Title: 13-(dihydro)cinnamyloxy- and 13-phenylcyclopropylmethoxy- substituted milbemycin derivatives and pharmaceutical, veterinary and pesticidal compositions
Inventor: YASUHIRO MORISAWA
IPC: C07H19/01
Filed: 1991-03-01
Abstract: A process of formula (I): <CHEM> [in which: R<1> is hydrogen, halogen, cyano, nitro, optionally substituted alkyl, alkoxy, alkoxyalkoxy, or a group of formula: <MATH>   <CHEM> in which: m is 1 or 2; n is 0, 1 or 2; R<6> is hydrogen or a variety of organic groups; R<7> is alkyl, cycloalkyl, or aralkyl; R<9> is hydrogen or alkyl; R<1><1> is any of R<6>, or cyano, nitro, -COOR<7> or -COR<6>; Y is an oxygen or a sulphur; Z is -COOR<7>, -COR<6> or -SO2R<6>; A is a group of formula: -CHR<2>-CHR<3>-CHR<4>- -CR<2>=CR<3>-CHR<4>- or <CHEM>  in which R<2>, R<3> and R<4> are hydrogen, halogen, alkyl or alkoxy; R<5> is methyl, ethyl, isopropyl or sec-butyl; and X is hydroxy, optionally substituted alkanoyloxy or hydroxyimino] and salts and esters thereof have valuable anthelmintic, acaricidal and insecticidal activities. Methods of preparing the compounds are also provided.
Patent NZ-238192-A (NZ)
Title: Liquid nutritional product to combat infantile colic
Inventor: TREEM WILLIAM REINHARDT
IPC: A23L1/305
Filed: 1991-05-20
Abstract: A novel liquid nutritional for use as an infant formula for use in the treatment of infantile colic is disclosed. The formula comprises protein, fat, carbohydrates and dietary fiber of a concentration of between 3.1 and 14.1 grams of fiber per liter of formula. Specific preferred protein, fat, carbohydrate and fiber sources are disclosed. Also disclosed is a method of treating infants with colic by feeding an infant the formula made in accordance with the invention. Also disclosed is a method for manufacturing the infant formula of the invention.
Patent NZ-256026-A (NZ)
Title: 40-, and/0r 28-alkoxylated rapamycin derivatives
Inventor: SEDRANI RICHARD
IPC: C07F7/18
Filed: 1993-09-24
Abstract: O-allylated rapamycin derivs. of formula (I) are new. X = (H,H) or O; Y = (H, OH) or O; R1 and R2 = each H, alkyl, thioalkyl, arylalkyl, hydroxyalkyl, dihydroxyalkyl, hydroxyalkylarylalkyl, dihydroxyalkylaralkyl, alkoxyalkyl, acyloxyalkyl, aminoalkyl, alkylaminoalkyl, alkoxycarbonylamino-alkyl, acylaminoalkyl, arylosulphonamido-alkyl, allyl, dihydroxyalkylallyl, dioxolanyl-allyl, carbalkoxyallyl or (R3)3Si; R3 = each H, Me, Et, i-Pr, t-Bu or Ph; R4 = Me; or R4 and R1 together form 2-6C alkylene; alk- or alkyl refer to 1-6C alkyl, branched or linear, esp. 1-3C alkyl, in which the carbon chain is opt. interrupted by an ether linkage; provided that T1 and R2 are not both it; and provided that when R1 is carboxyalkyl or (R3)3Si, X and Y are not both O. Dose is 0.05-10 mg/kg p.o. or 0.01-5 mg/kg. i.r.
Patent NZ-256450-A (NZ)
Title: Obtaining 10-deacetylbaccatin iii as a solvent extract from yew; use for preparing taxanes
Inventor: GAULLIER JEAN-CLAUDE
IPC: C12P17/02
Filed: 1993-10-04
Abstract: This invention relates to a process for obtaining 10-deacetylbaccatin III from various parts of yew (Taxus sp.) by extraction and selective crystallization starting with a methanolic extract of the vegetable matter.
Patent NZ-329532-A (NZ)
Title: Diazepino-indoles as phosphodiesterase iv inhibitors
Inventor: PASCAL YVES
IPC: A61P29/00
Filed: 1997-03-27
Abstract: Diazepino-indoles of the formula shown (wherein A is mono- to trisubstituted aryl or heteroaryl, and B is an -OR1 or -NR2R3 group where R1, R2 and R3 are particularly hydrogen), and racemic forms, enantiomers and pharmaceutically acceptable salts thereof, as phosphodiesterase IV inhibitors, are disclosed.  Intermediates are disclosed where the COA group is replaced by H.
Patent NZ-330957-A (NZ)
Title: Humanized green fluorescent protein genes (GFP) and methods
Inventor: ZOLOTUKHIN SERGEI
IPC: G01N33/48
Filed: 1997-01-17
Abstract: A humanized green fluorescent protein (GFP) gene with the Sequence ID No 2, expression vector operatively positioned downstream from a promoter, the promoter directing expression of the humanized GFP gene in a mammalian cell, the promoter is a CMV inducible promoter like cytochrome P450, heat shock protein, metallothionein or estrogen gene promoter, radiation inducible promoter or a tetVP16 promoter.