baber/WOPTO huggingface dataset:
Patent CA-2146010-A1 (CA)
Title: Ultrasonic transdermal drug delivery system
Inventor: LIPKOVKER LEV M
IPC: A61M37/00
Filed: 1993-10-13
Abstract: A transdermal drug delivery system that uses ultrasonic energy to release a stored drug and forcibly move the drug through the skin of an organism into the blood stream of the organism is disclosed. The transdermal drug delivery system includes a housing (81) having a cavity (67) for storing the drug to be de-livered. The cavity is defined by an assembly of ultra-sonic transducers (65) and is separated from the skin by a polymeric membrane (69). The ultrasonic trans-ducer assembly includes a flat, circular ultrasonic transducer (85) that defines the top of a truncated cone and a plurality of transducer segments (87a, 87b, 87c, 87d...) that define the walls of the cone. The resonant frequency of the planar transducer is lower than the resonant frequency of the transducer seg-ments. Located between the transducer assembly and the cavity is a drug-impermeable laminate (77) that also functions as a focusing lens for the transducers. Control electronics (63) and a power source (61) are also stored in the housing. In operation, the planar, flat, circular transducer generates fixed frequency (5KHz-1MHz range) ultrasonic stimuli impulses for a predetermined period of time (10-20 seconds). Between the stimuli pulse periods, the transducer segments receive variable frequency ultrasonic pumping pulses. The transducer segments create beams that impinge on the skin at an oblique angle and create a pulsating wave. A skin temperature sensor is in-cluded to prevent the ultrasonic signals from overheating the skin. The system may also include an infrared (IR) or laser transdu-cer for enhancing the operation of the drug delivery system by heating the skin and creating additional ultrasonic waves. Both open loop and closed loop (feedback) versions are provided. The closed loop version includes a sensor for sensing drug delivery effectiveness and using the resulting information to control the rate of drug delivery. The sensor uses ultrasonic energy to remove fluid from the skin for analysis.
Patent CA-2146982-A1 (CA)
Title: Digester for Converting Organic Material Into Compost
Inventor: FINN LARRY JAMES
IPC: C05F17/02
Filed: 1994-04-28
Abstract: A rotable digester drum (10) for converting organic waste material into compost which has internaly disposed along its longitudinal axis (14) perpendicular thereto a series of spaced baffles (16), each baffle (16) having a cross-sectional area ranging from 60-70% of the cross-sectional area of the drum (10) and the openings being arranged with respect to one another to cause material and air introduced into the drum (10) to traverse a non-linear path through the drum (10), the drum (10) having a plurality of longitudinally extending internal ribs (62) arranged in spaced array around its circumference.
Patent CA-2147843-A1 (CA)
Inventor: KUBOTA MASAO
IPC: B66B29/08
Filed: 1994-08-31
Abstract: La présente invention concerne un appareil de transfert continu dans lequel trois marches (1, 2, 3) alignées l'une derrière l'autre sont solidarisées entre elles par des bielles parallèles pour ne former qu'un seul trio de marches (123), les surfaces de ces marches restant horizontales en permanence. Lorsque le trio de marches arrive à l'extrémité terminale des premiers rails à secousses (01), il en sort et arrive sur la table de support (7). Celle-ci est maintenue par la rotation de roues à friction (91, 92) dans une rainure de guidage (03). Le trio de marches (123) disposé sur la table de support (7) est transféré avec la table de support (7) dans le sens latéral, empruntant un couloir de circulation défini par les rainures de guidage (03). Le trio de marches (123) qui se trouve sur la table de support (7) est alors envoyé vers les extrémités de début des deuxièmes rails à secousses (02) grâce à la rotation des roues à frictions (93, 94) et il progresse sur les rails à secousses (02) dans la direction opposée à la direction signalée précédemment. Pendant ce temps, le sens de circulation du trio de marches proprement dit ne change pas.
Patent CA-2148261-A1 (CA)
Inventor: PETERSON JERRY A
IPC: A61K35/55
Filed: 1993-10-29
Abstract: An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin complex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specificity of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infection in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention. A therapeutic method for inhibiting the onset of or countering rotavirus infection comprises administering to a subject afflicted with or at risk for rotavirus infections such as those occurring, for example, in infants and children (infantile gasteroenteritis) and immunodeficient persons or those who have received a transplant, an anti-rotaviral effective amount of the agent of this invention.
Patent CA-2150286-A1 (CA)
Title: Air cushioned spraying apparatus
Inventor: JONES DEREK
IPC: A01M7/00
Filed: 1995-05-26
Abstract: Air cushioned spraying apparatus for spraying vegetation with chemicals while being supported above the ground by an air cushion effect has a unit with at least three air cushion cells. Each cell has a substantially cylindrical rigid body with a closed upper end and an open lower end, and a flexible skirt secured to and extending around the periphery of the open lower end of the rigidbody. Each cell also has a spray nozzle projecting downwardly into the body fromthe closed upper end and an air inlet in the body adjacent the upper end thereof. The cells are connected together so that the path of travel of each cell laterally overlaps the path of travel of another cell. Air under pressure is supplied to the cell inlets to cause air to pass therethrough and downwardly in the cell body to disperse the chemicals from the nozzle onto vegetation within the lower open end of the cell and to cause air to pass from the cell between the flexible skirt and the ground to create an air cushion effect.
Patent CA-2150830-A1 (CA)
Inventor: LUCE DAVID A
IPC: A61B3/15
Filed: 1995-01-30
Abstract: L'invention concerne un instrument avec un affichage polaire ou vectoriel (26) qui fournit à l'opérateur d'un instrument optique des instructions symboliques relatives à la direction et à la distance de déplacement requises pour centrer un élément optique (16) sur un trajet choisi.
Patent CA-2155039-A1 (CA)
Title: Device for disintegration of material
Inventor: EKHOLM ROLF
IPC: B02C18/16
Filed: 1995-07-31
Abstract: A device for disintegration of material comprises a substantially horizontally arranged rotor (2) having a plurality of peripherically arranged disintegration elements (3) adapted to co-operate in a material disintegrating manner, at a place where disintegration elements of the rotor move downwardly, with a stationarily ar-ranged counter member (5) also contained in the device and a substantially vertical wall (11) extending along the rotor at the same side as the counter member and adapted to direct material coming from above between itself and the rotor downwardly to-wards the counter member. Said wall (11) consists entirely or par-tially of a resiliently yieldable material (12).
Patent CA-2155756-A1 (CA)
Title: Borrelia burgdorferi spirochete specific nucleic acid probes
Inventor: GODFROID EDMOND
IPC: C12Q1/689
Filed: 1994-02-18
Abstract: PCT No. PCT/BE94/00012 Sec. 371 Date Aug. 21, 1995 Sec. 102(e) Date Aug. 21, 1995 PCT Filed Feb. 18, 1994 PCT Pub. No. WO94/19488 PCT Pub. Date Sep. 1, 1994The invention relates to an oligonucleotide agent suited to use in evidencing at least one strain of Borrelia burgdorferi. Proposed are sequences common to all the groups of Borrelia burgdorferi strains, suited to use either as primers during genetic amplification reactions, or as capture probes in a hybridization test on a solid support on which the target DNA is "sandwiched" between the said capture probe and a disclosure probe, or else as disclosure probes in the said hybridization test on a solid support. Also proposed are sequences specific to each of the groups of Bb strains, suited to use as primers during genetic amplification reactions or as disclosure or capture probes in the hybridization test on the solid support mentioned above.
Patent CA-2156012-A1 (CA)
Title: Spindle adapter apparatus for paper roll product
Inventor: MOODY JOHN R
IPC: B65H75/08
Filed: 1995-08-14
Abstract: Apparatus for mounting a paper roll product having a core on a coreless paper roll spindle having an enlargement. The apparatus includes an adapter spindle for sliding over the coreless paper roll spindle and a lock within the interior of the adapter spindle for locking the coreless paper roll spindle and the adapter spindle against substantial relative axial movement.
Patent CA-2156636-A1 (CA)
Title: Donnees par paquets dans un systeme de radiotelephone cellulaire analogique
Inventor: JAYAPALAN JAY P
IPC: H04L12/56
Filed: 1994-12-21
Abstract: L'invention concerne un procédé et un appareil pour assurer la communication de données par paquets par voies de trafic pour un seul utilisateur et à commutation de circuits dans un système de radiotéléphone cellulaire. Cet appareil comprend une station de base (10) et une unité de données mobile (5) pouvant tous deux être utilisés pour établir une connexion d'appels de données à commutation de circuits, ou une voie de trafic de données par paquets sans connexion, pour un seul utilisateur, via une voie radioélectrique (7) et pour communiquer des données par paquets sur la voie radioélectrique établie.
Patent CA-2160668-A1 (CA)
Inventor: BLAND LINDEN H
IPC: E21B43/12
Filed: 1995-02-16
Abstract: A tubing rotator and hanger that attaches to a wellhead for suspending and rotating a tubing string contained in a wellbore. The tubing hanger comprises a support flange (64) which mounts on the wellhead flange (26). The tubing rotator comprises a tubular outer member (68) which engages the support flange, a tubular inner mandrel (80) which is connected to the tubing string (24) and which is rotationally supported within the outer member, apparatus (20) for rotating the inner mandrel which engage the inner mandrel at its upper end, and a housing (102) mounted around the upper end of the inner mandrel for a supporting the portion of the wellhead located above the tubing rotator. The rotating apparatus may be disengaged from the inner mandrel and the housing (102) is removable so that a blowout preventer may be placed on top of the support flange (64) and over the outer member (68) and the inner mandrel (80) and mounted on the wellhead without first moving the tubing string, and so that the outer member, the inner mandrel and the tubing string (24) may be pulled through the blowout preventer to service the well. An adaptor is provided so that the rotating apparatus may be driven automatically by a rotating polished rod. The adaptor comprises a sleeve that fixedly mounts on the rotating rod, a shaft which engages the sleeve in order to be rotated as the sleeve rotates, and an adaptor housing for supporting the first shaft mounted about the sleeve so that the sleeve may rotate within the adaptor housing. The first shaft is connected to the rotating apparatus by a flexible second shaft, and the rotating apparatus includes a gearbox which creates a mechanical advantage so that rotation of the rotating rod rotates the inner mandrel and the tubing string.
Patent CA-2161558-A1 (CA)
Title: Procede de fabrication de rouleaux pour le gauffrage en continu de pellicule thermoplastique
Inventor: MINKE JUERGEN
IPC: B29C33/40
Filed: 1995-10-27
Abstract: Procédé de fabrication d'un rouleau de gaufrage à revêtement silicone pour gaufrer en continu la surface de films thermoplastiques. Un faisceau laser est utilisé pour pratiquer, dans la surface en caoutchouc silicone lisse du rouleau, un motif ou un modèle reproduisant par exemple un négatif d'un grain de cuir. L'intensité du faisceau laser et de son mouvement est commandée par un signal généré en balayant le grain de cuir d'origine. Ce procédé permet de produire simplement et économiquement une structure gaufrée dans la surface en silicone d'un rouleau de gaufrage, même lorsque la structure à répéter est extrêmement fine. Aucune étape manuelle fastidieuse n'est nécessaire pour réaliser la reproduction du gaufrage la plus naturelle possible.
Patent CA-2162610-A1 (CA)
Title: Peptides utiles pour arreter la proliferation de cellules souches myeloides et traiter le choc septique
Inventor: MOORE ROBERT N
IPC: C07K7/06
Filed: 1994-05-18
Abstract: Des peptides contenant la séquence Ala-Lys-Pro-Arg présentent des effets suppresseurs sur la prolifération d'un large éventail de cellules souches myélopoïétiques. Dans un mode de réalisation préféré, le peptide présente la séquence Glu-Thr-Val-Ile-Met-Lys-Ala-Lys-Pro-Arg-Ala-Asn-Phe-Pro. Les peptides de l'invention sont utiles dans le traitement de troubles hyperprolifératifs myélopoïétiques, et dans la production de cellules myéloïdes contre une détérioration induite par chimiothérapie et par rayonnement. Des peptides contenant la séquence Ala-Lys-Pro-Arg sont également utiles dans le traitement du choc septique induit par endotoxine.
Patent CA-2162855-A1 (CA)
Title: Expression of urokinase plasminogen activator inhibitors
Inventor: ROSENBERG STEVEN
IPC: C40B40/02
Filed: 1994-05-19
Abstract: A method for preparing a urokinase-type plasminogen activator inhibitor by expressing HuPA1-48 from yeast is disclosed.
Patent CA-2166225-A1 (CA)
Title: Circuit Breaker and Circuit Breaking Apparatus
Inventor: YAMAMOTO HIROSHI
IPC: H01H9/54
Filed: 1995-12-28
Abstract: A circuit breaker for a distribution system includes a non-self-extinction  type  semiconductor  switch,  a  current limiting element connected in series to the semiconductor switch for suppressing a fault current.   The semicondutor switch and the current limiting element constitute a series circuit.   A mechanical type high-speed switch is connected in  parallel  to  the  series  circuit  of  the  semiconductor switch and the current limiting element.  Upon occurrence of a  fault  in  the  distribution  system,  an  electric  current flowing through the distribution system is commutated to the series circuit from the mechanical type high-speed switch.
Patent CA-2172219-A1 (CA)
Title: High performance card edge connector
Inventor: HARWATH FRANK A
IPC: H01R12/72
Filed: 1996-03-20
Abstract: A high  performance  card  edge  connector  (10) includes a housing (16) with an elongated printed circuit card receiving slot (38)  in a top wall (18).   Terminals (44,46,48)  are  mounted  in  transverse  cavities  (28) intersected by the slot.  Alternate cavity portions (28A) receive a pair of signal terminals (44,46) and interspersed alternate  cavity  portions  (28B)  receive  single  ground terminals  (48).    Each  terminal  includes  a  downwardly extending board contact portion (52,64,74) for connection to a printed circuit board and a card contact portion (56,68,80) in the slot for engagement with a contact pad of an inserted card.  Each signal terminal pair may be flanked by two ground terminals on the same side of the slot and may be transversely opposite a ground terminal on the opposite side of the slot.   A uniform identical cavity configuration permits each cavity portion to receive either a ground terminal or a pair of signal terminals.
Patent CA-2174248-A1 (CA)
Title: Clear Molded Thermoplastic Compact Disc Supporting Tray
Inventor: JOYCE MICHAEL PATRICK
IPC: G11B33/04
Filed: 1995-03-30
Abstract: A clear plastic box having a cover is hinged to a bottom member includes a relatively brittle clear (translucent or transparent) thermoplastic molded compact disc (CD) receiving tray, typically polystyrene. The tray has a central rosette of inwardly extending resilient fingers each with an outer radially facing recess for resiliently receiving the CD via a rim at the CD central opening. A plurality of molded ribs rigidify at least two pairs of opposing fingers to preclude breakage of the fingers during resilient displacement. The rigid fingers receive the CD in resilient deformation of either the fingers or CD or both without damage to the CD and fingers. All of the fingers may be rigid with a corresponding rib.
Patent CA-2174649-A1 (CA)
Title: Prodrugs of an inhibitor of hiv protease
Inventor: ALEXANDER JOSE
IPC: A61K31/495
Filed: 1994-11-14
Abstract: Prodrugs of formula (I) are useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition in-gredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Patent CA-2175309-A1 (CA)
Title: Method and apparatus for contact lens mold filling and assembly
Inventor: ANDERSEN FINN THRIGE
IPC: G02C13/00
Filed: 1996-04-29
Abstract: An apparatus for forming contact lenses, wherein front curve mold halves are filled with a hardenable transparent material, such as a polymerizable hydrogel, and back curve mold halves are coupled to the front curve, therein forming a lens. More particularly, the apparatus includes a conveyor means for transporting pallets of mold halves to the apparatus, an array of piston structures for raising and aligning the back curves with respect to the filled front curve halves, reciprocating means for reciprocating the piston array to couple pairs of front and back curves, and a vacuum chamber and vacuum drawing means for maintaining a vacuum around the curves during coupling. In addition, there is provided individual spring biasing to each reciprocating element whereby sensitivity to thickness variations and pallet misfeeds may be minimized.  Further, there is provided a vacuum sleeve, through which the pistons reciprocate within the vacuum chamber, which sleeve preserves the vacuum within the chamber.
Patent CA-2176525-A1 (CA)
Title: Fluorescent compounds
Inventor: BELL COLIN DAVID
IPC: C09K11/06
Filed: 1996-05-14
Abstract: Novel compounds obtainable by reacting together an imido-reagent such as diphenylphosphonimido--triphenylphosphorane), or a phosphine oxide such as p--tolyldiphenylphosphine oxide, with a chelate of a transition or lanthanide or actinide metal, such as tris(dibenzoylmethide) europium III, have the property of fluorescing in UV radiation. The invention includes solid polymer bodies containing such compounds, or chelates of transition or lanthanide or actinide metals generally, the bodies having the property of emitting light or infra-red radiation when subjected to a flux of ultra-violet or ionising radiation by virtue of internally generated, e.g. by tritium ionising radiation. The body is preferably of polystyrene formed by polymerising the monomer in the presence of the compound or metal chelate.
Patent CA-2177749-A1 (CA)
Inventor: MARKS BRUCE GEORGE
IPC: H01J29/86
Filed: 1996-05-30
Abstract: An improved color picture tube includes a shadow mask and a dot screen, wherein the mask is rectangular and has two horizontal long sides and two vertical short sides. The long sides parallel a central major axis of the mask and the short sides parallel a central minor axis of the mask. The mask includes an array of apertures arranged in vertical columns and horizontal rows. Apertures in one row are in different columns than are the apertures in adjacent rows. The vertical spacing between apertures in the same column is the vertical pitch of the apertures and the horizontal spacing between apertures in the same row is the horizontal pitch of the apertures. The improvement comprises the horizontal pitch of the apertures increasing from the minor axis to the short sides of the mask and decreasing from the major axis to the long sides of the mask. Also, along the major axis, the vertical pitch of the mask decreases from the center to the short sides of the mask and, adjacent the long sides of the mask, it increases from the minor axis to the corners of the mask.
Patent CA-2179298-A1 (CA)
Title: Information display system for actively redundant computerized process control
Inventor: FELIX BRADLEY K
IPC: G06F3/048
Filed: 1994-12-21
Abstract: In an actively redundant computer system, in which two or more computer simultaneously control a process, live data values representing the actual state of preselected variables are simultaneously displayed along with an alphanumeric representation of a source code statement based on those variables.
Patent CA-2179643-A1 (CA)
Title: Novel 6-substituted oxa- or azasteroid compound
Inventor: KOIZUMI NAOYUKI
IPC: C07J73/00
Filed: 1994-12-20
Abstract: A 6-substituted oxa- or azasteroid compound represented by general formula (I), having an excellent aromatase inhibitory activity, and being useful for preventing or treating diseases caused by estrogens, such as mammary cancer, uterus carcinoma, prostatic hypertrophy, and so forth. This compound has an oxygen or nitrogen atom in the steroidal D ring and the 6-position (R1) is substituted by -S-R2 (R2 representing hydrogen, lower alkyl, cyano or acyl), O-R3 (R3 representing hydrogen, lower alkyl, or acyl), azido or amino.
Patent CA-2180982-A1 (CA)
Title: Process for producing n-butyraldehyde and/or n-butanol
Inventor: KANAND JUERGEN
IPC: C07C41/06
Filed: 1995-01-12
Abstract: In a process for producing n-butyraldehyde and/or n-butanol, (a) 1,3-butadiene is reacted with an alcohol having the formula ROH, in which the residue R  stands for a non-substituted C2-C20-alkyl or alkenyl group that may also be substituted by 1 or 2 C1-C10-alkoxy or hydroxy groups, a C6-C10-aryl or C7-C11-aralkyl group or the methyl group, at a higher temperature and pressure in the presence of a Brönsted acid or in the presence of a compound of an element from groups IB, VIIb or VIIIb of the periodic table of elements with phosphoric or nitrogenated ligands, so as to produce a mixture of addition compounds having the formulas (II) and (III); (b) the addition compound III is isomerised into the addition compound II; (c) the addition compound II is isomerised in the presence of a homogeneous or heterogeneous transition metal element catalyst in liquid phase or in the presence of a heterogeneous transition metal element-containing catalyst in gaseous phase, so as to produce an enol ether having the formula (IV); and (d) n-butyraldehyde and/or n-butanol are generated by reacting said enol ether IV with hydrogen and water or with water in the presence of a homogeneous or heterogeneous transition metal element catalyst in the liquid phase or in the presence of a heterogeneous transition metal element-containing catalyst in the gaseous phase. The alcohol ROH released is recycled into the partial reaction (a).
Patent CA-2181794-A1 (CA)
Inventor: SCHECHTMAN LEE ARNOLD
IPC: A61L15/62
Filed: 1995-01-13
Abstract: The present invention relates to a method of preparing a polyester comprising polymerizing at least one .beta.-substituted-.beta.-pnopiolactone in the presence of an initiating amount of alkylzinc alkoxide in bulk or in solvent for a reaction time and temperature sufficient to produce said polyester.