baber/WOPTO huggingface dataset:
Patent DE-69112080-D1 (DE)
Inventor: CHAN MING
IPC: A61K31/5575
Filed: 1991-12-04
Granted: 1995-09-14
Abstract: The present invention relates to 2-decarboxyl-2-alkoxyalkyl prostaglandins that are potent ocular hypotentives, and are particularly suitable for the management of glaucoma. Said 2-decarboxyl-2-alkoxyalkyl prostaglandins are compounds of the formula (I)   <IMAGE>  wherein the wavy line attachments indicate either alpha ( alpha ) or beta ( beta ) configuration; hatched lines indicate  alpha  configuration; solid triangles are used to indicate beta  configuration; the dashed bonds represent a single bond or a double bond which can be in the cis or trans configuration; R is an aliphatic hydrocarbon group having from 1 to about 6 carbon atoms; one of R1 and R2 is=O, -OH or a -O(CO)R6 group, and the other one is -OH or a -O(CO)R6 group or R1 is=O and R2 is H, R3 is -OH or -O(CO)R6; R4 and R5 independently are hydrogen or an aliphatic hydrocarbon group having from 1 to about 6 carbon atoms; R6 is a saturated or unsturated acyclic hydrocarbon group having from 1 to about 20 carbon atoms, or -(CH2)nR7 wherein n is 0-10, and R7 is an aliphatic ring from about 3 to about 7 carbon atoms or an aromatic or heteroaromatic ring; or a pharmaceutically acceptable salt of said compound. The invention also provides a pharmaceutical product including a container adapted to dispense an ophthalmic solution in metered form and containing said 2-decarboxyl-2-alkoxyalkyl prostaglandin in admixture with a non-toxic, ophthalmically acceptable liquid vehicle.
Patent DE-69116423-D1 (DE)
Inventor: ANIMATI FABIO
IPC: C07D303/32
Filed: 1991-05-10
Granted: 1996-02-29
Abstract: New 8-fluoroanthracycline derivatives of formula I possessing antitumoral properties are described, together with their preparation and pharmaceutical compositions containing them.
Patent DE-69119557-D1 (DE)
Inventor: SAGAWA MASATO
IPC: B30B15/02
Filed: 1991-11-28
Granted: 1996-06-20
Abstract: In the die-pressing method of the magnet powder and fine powder, the powder is filled at a high density in a rubber mold (10), is occasionally preliminarily magnetized (4a) in the rubber mold and is then compacted under magnetic field or without magnetic field. Cracking of the magnet green compact is prevented. A sintered compact having density of 90% or more can be produced using the fine powder. <IMAGE>
Patent DE-69123220-D1 (DE)
Inventor: MISAWA RINTARO
IPC: A61G5/06
Filed: 1991-08-02
Granted: 1997-01-02
Abstract: A stair-climbing wheelcarrier comprises a carrier portion comprising a pair of endless belt crawlers and a handle rotatably mounted on the carrier portion. A guide body is provided to mount a wheelchair and secured to the handle so as to be pivoted together with the handle. An electric screw jack is provided between the carrier portion and the guide body for holding the guide body at a desired position. <IMAGE>
Patent DE-69128805-D1 (DE)
Inventor: YOSHIDA AKIHIKO
IPC: H01G9/00
Filed: 1991-03-22
Granted: 1998-03-05
Abstract: An electric double layer capacitor which comprises a pair of polarizable electrode (4, 5), composed of electrically-conductive substrates (1) coated with layers formed on said substrates, of a mixture of activated carbon with a water-soluble material-based binding agent, optionally including an agent for improving electric conductivity, facing with each other by being interposed with a separator (6), and an electrolyte is disclosed. <IMAGE>
Patent DE-69131933-D1 (DE)
Inventor: NOWAKOWSKI MARK RONALD
IPC: C12M1/34
Filed: 1991-03-11
Granted: 2000-03-02
Abstract: Devices for use in either competitive or non-competitive ligand-receptor assays, having a microporous member in contact with a non-absorbent textured surface, where the surface texturing is such that a capillary network is formed when in contact with the microporous member. More particularly, these devices comprise: a porous member having an upper and a lower surface, being positioned in the device such that said sample may be applied to said upper surface; and a non-absorbent member having a textured surface with channels capable of forming a network of capillary channels when placed in communication beneath or around said porous member, said capillary network being substantially parallel to the lower surface of said porous member; whereby the sample, alone or in combination with other fluids,when applied to said upper surface is drawn through said porous member to said capillary network formed between said porous member and said non-absorbent member when substantially all the void volume of said porous member is filled with said sample and/or fluids and when contact is made between said porous member and said non-absorbent member. These devices are suitable for use in ligand-receptor assays which are performed using either immunochromatographic methods or in those which are performed using flow-through methods. <IMAGE>
Patent DE-69214149-D1 (DE)
Inventor: KELSEY DONALD
IPC: C08G61/08
Filed: 1992-07-08
Granted: 1996-10-31
Abstract: An improved thermoset polymer having good mechanical properties and no detectable dicyclopentadiene odor is obtained by the ring-opening polymerization of a novel mixture of adducts comprising divinyl cyclohydrocarbon compound, such as 3,5-divinylcyclopentene and cyclopentadiene, optionally with added cycloolefinic compound, such as dicyclopentadiene, at polymerization conditions in the presence of an olefin metathesis catalyst.
Patent DE-69300517-D1 (DE)
Inventor: HOUDOIN THIERRY
IPC: H04J3/14
Filed: 1993-12-14
Granted: 1995-10-26
Abstract: The invention relates to a method and an apparatus for generating binary errors in an incoming signal whose format and bit-rate correspond to the transmission standards of a network especially to transmission in ATM mode. The apparatus therefore includes programming means (1) making it possible to record various error templates relating to transmission over various networks and to read the desired template in tempo with the incoming signal so as to introduce error bits into this signal. The invention applies to the simulation of transmission networks, especially ATM networks. <IMAGE>
Patent DE-69303943-D1 (DE)
Inventor: SAKAI YASUYOSHI
IPC: C12N9/04
Filed: 1993-02-26
Granted: 1996-09-19
Abstract: The present invention relates to an expression vector which is induced by methanol and/or glycerol utilizing an alcohol oxidase gene of a methylotrophic yeast; a recombinant methylotrophic yeast containing said vector and capable of accumulating a significantly high amount of an expression product of a heterologous gene; and a method for producing useful products utilizing said recombinant. The expression vector is constructed by utilizing the promoter and terminator of an alcohol oxidase gene of methylotrophic yeast. Further, a significantly high amount of adenylate kinase, cytochrome C552 or peroxidase is produce by using said expression vector.
Patent DE-69308086-D1 (DE)
Inventor: GUTH JEROME
IPC: B23K26/20
Filed: 1993-07-26
Granted: 1997-03-27
Abstract: The subject of the invention is a method of butt welding at least two metal sheets (1, 2) of various thicknesses, by means of a laser beam (3). The method consists in bringing the metal sheets (1, 2) into contact at their side faces (4, 5) to be joined end to end, in directing the laser beam (3) towards the thicker metal sheet (1) so that the vertical axis X-X, which passes through the focal point P of the laser beam (3) on the said metal sheet (1), is at a defined distance from the junction plane (7) of the metal sheets, and in producing a welded joint at the side faces (4, 5) joined end to end, by locally melting the said metal sheets by means of a laser beam (3). <IMAGE>
Patent DE-69321465-D1 (DE)
Inventor: MATERNAGHAN DAVID
IPC: C09K13/06
Filed: 1993-05-17
Granted: 1998-11-12
Abstract: PCT No. PCT/GB93/01003 Sec. 371 Date Dec. 19, 1994 Sec. 102(e) Date Dec. 19, 1994 PCT Filed May 17, 1993 PCT Pub. No. WO93/23493 PCT Pub. Date Nov. 25, 1993.An aqueous composition for etching and cleaning semiconductor devices comprises a solution of an acid and a surfactant which is a branched chain aliphatic amine having the formula CmH2m+3N, where m is an integer from 7 to 10. The compositions are stable for long periods of time and do not suffer foaming problems when used in recirculation filtration systems.
Patent DE-69322963-D1 (DE)
Inventor: PALARA SERGIO
IPC: H01L27/06
Filed: 1993-09-17
Granted: 1999-02-18
Abstract: A device integrated on a chip of a semiconductor material is disclosed which comprises an NPN bipolar transistor (T2) and an N-channel MOSFET transistor (T3) in an emitter switching configuration, both being vertical conduction types. The bipolar transistor (T2) has its base (13) and emitter (14) regions buried; the MOSFET transistor (T3) is formed with an N region (16) bounded by the base (13) and the emitter (14) regions and isolated by a deep base contact and isolation region (15). To improve the device performance, especially at large currents, an N+ region (17) is provided which extends from the front of the chip inwards of the isolated region (16) and around the MOSFET transistor (T3). In one embodiment of the invention, a MOSFET drive transistor (T1) is integrated which has its drain terminal in common with the collector (C) of the bipolar transistor (T2), its source terminal connected to the base of the bipolar transistor (T2), and its gate electrode connected to the gate electrode (G) of the MOSFET transistor (T3) in the emitter switching configuration. <IMAGE>   <IMAGE>
Patent DE-69328359-D1 (DE)
Inventor: BRADY G
IPC: A61F2/16
Filed: 1993-02-25
Granted: 2000-05-18
Abstract: An intraocular lens for implantation in an eye comprising a deformable silicone optic configured so that the optic can be deformed to permit the intraocular lens to be passed through a scleral tunnel incision no longer than about 3.2 mm into the eye. The intraocular lens can be provided in a range of diopter powers. When the intraocular lens is implanted in the eye, the optic has sufficient rigidity to be substantially free of optical distortion resulting from force from the eye acting on the intraocular lens and the optic is of sufficient size to substantially prevent glare resulting from interaction of light and the periphery of the optic.
Patent DE-69328368-D1 (DE)
Inventor: AVIV HAIM
IPC: A61K9/107
Filed: 1993-01-05
Granted: 2000-05-18
Abstract: An ocular drug delivery vehicle of an oil-in-water submicron emulsion comprising about 0.5 to 50% of a first component of an oil, about 0.1 to 10% of a second component of an emulsifier, about 0.05 to 5% of a non-ionic surfactant and an aqueous component, with the mean droplet size being in the submicron range, i.e., below about 0.5  mu m and preferably between about 0.1 and 0.3  mu m. Also, topical pharmaceutical compositions containing a drug such as an anti-glaucoma drug, beta adrenergic blocker or other autonomic system drug, a local anesthetic, a steroid, a non-steroidal anti-inflammatory drug, an antibiotic drug, an antifungal drug, an antiviral drug or combinations thereof and the vehicle described above. Methods of administering such vehicles or compositions to the eye of a patient while reducing irritation thereof and providing increased bioavailability of the drug.
Patent DE-69333899-D1 (DE)
Inventor: PETRANOVICH E
IPC: H04L7/08
Filed: 1993-12-30
Granted: 2005-12-08
Abstract: A digital demodulator and method for demodulating digital data representing a phase shift keyed (PSK) signal are provided. The demodulator comprises a phase detector, automatic frequency controller, automatic timing recovery controller, data decoder, and unique word detector. According to the method of the present invention, a PSK signal is received and digitized to substantially remove the signal's amplitude characteristics. The phase detector receives an input of the digital data and based upon transitions in the data from a high state to low state and from a low state to a high state, provides phase estimates. The phase estimates are converted by the data decoder into binary data representing the symbols transmitted to form the PSK signal. A number of overlapping windows of digital data are used to determine phase estimates. The unique word detector receives an input of binary data from the data decoder and using a correlation technique identifies one set of windows which substantially maximizes synchronization of the demodulator with the received PSK signal. After the synchronizing window has been identified the automatic frequency controller monitors any frequency drift of the PSK signal and corrects the phase estimates based on the frequency error. The automatic timing recovery controller uses the corrected phase errors from early and late windows with respect to the synchronizing window to adjust the timing of the synchronizing window by advancing or delaying the demodulator's symbol timing signal to further maximize synchronization with the received PSK signal.
Patent DE-69420289-D1 (DE)
Inventor: BECHTOLDT WAYNE
IPC: A47C31/06
Filed: 1994-03-23
Granted: 1999-09-30
Abstract: PCT No. PCT/US94/03112 Sec. 371 Date Nov. 1, 1994 Sec. 102(e) Date Nov. 1, 1994 PCT Filed Mar. 23, 1994 PCT Pub. No. WO95/25454 PCT Pub. Date Sep. 28, 1995An anchor clip for holding an edge of a cushion-supporting upholstery spring in position on a wooden rail of an article of furniture, the clip having a base portion, a leg portion, and reversed curved portion, the reversed curved portion defining a hook which is inwardly lined with a plastic liner. Lateral edges of the hook are flared outwardly to relieve pressures at both sides of the liner. The free end of the hook is folded-over to entrap one end of the liner and subsequently staked. In another embodiment, the hook, at the acme of the curvature, is provided with a cut-out and flared area on each lateral side of the hood for relieving pressure on the liner.
Patent DE-69501591-D1 (DE)
Inventor: MORELLI LORENZO
IPC: A61K35/74
Filed: 1995-05-18
Granted: 1998-03-12
Abstract: The present invention concerns Lactobacillus strains and pharmaceutical compositions containing them.
Patent DE-69506933-D1 (DE)
Inventor: ARLES LOUIS
IPC: A47C20/04
Filed: 1995-04-11
Granted: 1999-02-11
Abstract: An adjustable bed consists of a fixed base (1) supporting a horizontal (3) and at least one movable (2) section which can be set at an angle relative to the horizontal one. The pivoted head section of the bed is raised or lowered by means of at least one bar connected to a drive motor which also moves the horizontal section as the head section's position is altered. The horizontal section of the bed is mounted on a frame which is able to move relative to the fixed base. The adjustable section is operated by two bars linked by a cross-member with rollers. In a variant of the design, the bars can be actuated by two-arm levers connected to power cylinders beneath the fixed base. <IMAGE>
Patent DE-69515363-D1 (DE)
Inventor: HAND EDWARD
IPC: F16L25/02
Filed: 1995-05-16
Granted: 2000-04-13
Abstract: An insulation piercing earthing ring 16 for a gland termination to provide earth continuity between an electrically conductive gland body 6 and an electrically conductive inner sleeve 2 of an insulated cable or pipe 1 comprises a flat annular washer 17 for locating against the end of the cable or pipe 1 with at least one contact finger 18 extending from the periphery of the washer 17 to surround the cable or pipe 1 and terminating in an inwardly directed projection 19 for piercing the insulation 4. The contact finger 18 extends axially and radially outwards from the periphery of the washer 17 in the undeformed free state and is/are deformed radially inwards by engagement with a tapered entry portion 11 of the gland body 6 causing the projection 19 to pierce the insulation 4 and contact the electrically conductive inner sleeve 2. <IMAGE>
Patent DE-69519112-D1 (DE)
Inventor: NILSSON G
IPC: C12P19/26
Filed: 1995-07-13
Granted: 2000-11-16
Abstract: PCT No. PCT/IB95/00561 Sec. 371 Date Jun. 16, 1998 Sec. 102(e) Date Jun. 16, 1998 PCT Filed Jul. 13, 1995 PCT Pub. No. WO97/03206 PCT Pub. Date Jan. 30, 1997Disclosed is a method of producing a compound which contains the Glc beta 1-4GlcN structure involving reacting at least one donor substance Glc beta OR where R is an organic group, and at least one acceptor substance which is a glucopyranosamino derivative having the formula GlcNR''-R''', wherein NR'' is an azido, 2-N-acetyl-, 2-N-phtalimido, or an organic group bound to the 2-N-group of glucosamine, wherein R''' is a glycosidically bound fluoro or is an O-, C-, N- or S-glycosidically bound aliphatic or aromatic compound, with the optional proviso that if NR'' is NHAc then R''' is not OH and if NR'' is not NHAc then R''' may be OH, in the presence of Bullera singularis or an E.C. group 3.2 glycosidase of essentially the same structure as an E.C. group 3.2 glucosidase obtained from Bullera singularis to form the Glc beta 1-4GlcN derivative; and optionally isolating the compound which contains the Glc beta 1-4GlcN structure.
Patent DE-69520146-D1 (DE)
Inventor: INGHAM EDWARD
IPC: D06M13/244
Filed: 1995-08-08
Granted: 2001-03-29
Abstract: A method of treating wool and/or other natural fibres with a chemical compound, the compound undergoing photoyellowing at a similar rate to the rate at which the wool and/or natural fibres undergoes photobleaching. The chemical compound is applied in an amount which ensures the photoyellowing of the chemical compound cancels out the photobleaching of the natural fibres. The chemical compounds are preferably syntans and may consist of condensation products of aromatic sulphonic and/or sulphonic acids. Other suitable compounds include optical brightening agents, tannins, and aromatic sulphonic acids.
Patent DE-69521388-D1 (DE)
Inventor: BAGGIO BRUNO
IPC: A61K31/727
Filed: 1995-09-04
Granted: 2001-07-26
Abstract: The use of some glycosaminoglycans like sulodexide, low molecular weight heparin and low molecular weight dermatan sulfate and of the medicines by parenteral use that contain them in the treatment of patients suffering from chronic renal insufficiency subjected to peritoneal dialysis is the object of the present invention. The effectiveness of this use has been shown both by pharmacological studies carried out in nephrectomized rats to whom a peritoneal damage has been caused and by clinical studies carried out in patients suffering from chronic renal insufficiency subjected to CAPD and treated by intraperitoneal route (i.p.) with 2 ml vials of VESSEL DUE F TM  containing 50 mg of sulodexide. A significant increase of the peritoneal transports of urea and of creatinine joined to a significant decrease of the protein-loss in the peritoneal effluent has been observed. Significant changes of the ultrafiltration capacity and of haemorrhagic-coagulative complications have not been observed during the study.
Patent DE-69525638-D1 (DE)
Inventor: SZU CHEN
IPC: A61K39/02
Filed: 1995-09-28
Granted: 2002-04-04
Abstract: The present invention is a modified plant, fruit or synthetic oligo- or polysaccharide which has been structurally altered so as to render the modified saccharide antigenically similar to the Vi of Salmonella typhi. The modified saccharide may be conjugated to a carrier to form a conjugate that is immunogenic against S. typhi. Antibodies produced in response to the immunogenic conjugate are protective against typhoid fever. Methods are provided for making the modified saccharide and the immunogenic conjugate.
Patent DE-69526781-D1 (DE)
Inventor: KONDO MICHIO
IPC: D06N3/00
Filed: 1995-06-27
Granted: 2002-06-27
Abstract: A floor material which generates no harmful gas such as hydrogen chloride at the time of a fire, is suitable for dry maintenance with a high speed buffing machine and has excellent resistances against flaws, stains, abrasion and the like, which is also a floor material having markedly excellent adhesiveness to the floor ground. This invention is characterized in that a wax is contained in an amount of from 1 to 10% by weight in at least the surface layer of the floor material in which an olefinic resin is used as the base material and an inorganic filler is blended therein. Preferably, a back side layer of an ethylene-vinyl acetate copolymer or a mixed resin of said copolymer and other olefinic resin is used as its base material having an inorganic filler is blended therein is laminated on the under side of the surface layer, and 1 to 10% by weight of rosin is included in said back side layer. The inventive floor material can be used broadly as the flooring in, for example, constructions such as buildings, apartment houses and the like and transportation means such as cars, ships, aircraft and the like. <IMAGE>
Patent DE-69528820-D1 (DE)
Inventor: TIMMER CHRISTIENA JANNIE
IPC: A61K35/20
Filed: 1995-04-28
Granted: 2002-12-19
Abstract: The present invention is related to a mouth-care product comprising an effective amount of colostrum and/or a colostrum extract, preferably based on bovine colostrum.
Patent DE-69530973-D1 (DE)
Inventor: BRISKIN E
IPC: A61K47/44
Filed: 1995-02-14
Granted: 2003-07-10
Abstract: A process for preparing fine particle pharmaceutical formulations having improved throughput and producing greater uniformity of particle size. The process relates to adding to the dry components of the formulation prior to the steps of wetting, extrusion and spheronization, an extrusion aid material selected from pharmaceutically acceptable oils and waxes having a drop point between about 15 DEG  C. and 115 DEG  C.
Patent DE-69531041-D1 (DE)
Inventor: TOURNIER HERVE
IPC: A61K9/127
Filed: 1995-09-28
Granted: 2003-07-17
Abstract: The invention relates to a dry deposit as a precursor to liposome vesicles, the precursor being a three dimensional expanded structure with bulk density between 0.01 and 0.001 g/cm3. The invention also concerns a method of making liposome vesicles with an enhanced entrapment capacity by dissolving one or more film forming lipids in at least one organic solvent to form a solution in a reaction vessel, evaporating the solvent to form an expanded three dimensional porous lipid structure, contacting the lipid deposit with an aqueous carrier phase, and producing liposome vesicles entrapping the carrier phase as well as an apparatus comprising an array of tubing or an inert packing which serves as a material support or a matrix surface for the deposition of lipids produced according to the method.
Patent DE-69535575-D1 (DE)
Inventor: EGHOLM MICHAEL
IPC: C12Q1/6813
Filed: 1995-07-13
Granted: 2007-10-04
Abstract: Novel peptide nucleic acids and novel linked peptide nucleic acids, form triple stranded structures with nucleic acids. The peptide nucleic acids include ligands such as naturally occurring nucleobases attached to a peptide backbone through a suitable linker. Other nucleobases including C-pyrimidines and iso-pyrimidines can be used as the ligands in Hoogsteen strands to increase binding affinity. Two peptide nucleic acid strands are joined together with a linker to form a bis-peptide nucleic acid. The individual strands of the peptide nucleic acids in the bis compounds can be orientated either parallel or antiparallel to each other.
Patent DE-69609557-D1 (DE)
Inventor: ASANO EIICHI
IPC: C08G59/32
Filed: 1996-03-08
Granted: 2000-09-07
Abstract: An epoxy resin composition comprising (A) 20-80 parts by weight of an epoxy resin, (B) 20-80 parts by weight of a curing agent, (C) 0.1-50 parts by weight of a phosphorus-containing flame retardant, and (D) 200-1,200 parts by weight of an inorganic filler cures into products having improved high-temperature exposure resistance, flame retardancy, and reflow cracking resistance. The composition eliminates blending of antimony trioxide and brominated compounds and is useful in encapsulating semiconductor devices for imparting high-temperature reliability.