baber/WOPTO huggingface dataset:
Patent FI-925736-A0 (FI)
Inventor: CERCEK BORIS
IPC: A61K47/48
Filed: 1992-12-17
Abstract: A cancer recognition factor (SCM factor) useful in the performance of the structuredness of the cytoplasmic matrix (SCM) test has been isolated, purified to substantial homogeneity, and characterized, and methods for its use have been described. The factor is a peptide of at least 9 amino acid residues including a core sequence of 9 amino acid residues having an amphipathicity profile substantially equivalent to that of the sequence F-L-M-I-D-Q-N-T-K and produces at least a 10 percent decrease in the intracellular fluorescence polarization value of SCM-responding lymphocytes from donors afflicted with cancer. A synthetic SCM factor representing a consensus sequence of M-I-P-P-E-V-K-F-N-K-P-F-V-F-L-M-I-D-Q-N-T-K-V-P-L-F-M-G-K is fully active. Antibodies specific for SCM factor are useful in immunoassays that can detect the factor, including detection in cancer cells grown in vitro. The SCM factor is useful for screening of blood samples and other body fluids or cell aspirates for the presence of malignancy in the donor. The multiple action spectrum of the SCM factor including cancer proliferation and invasion promotion, as well as inhibition of the host's immune defense mechanisms and synthesis of SCM factor by cancer cells, represents a novel target for cancer management. Methods for reducing in vivo activity of the SCM factor, such as dialysis or antibody neutralization, can also be useful in the management of cancer.
Patent FI-925782-A0 (FI)
Inventor: GRIESBACHER THOMAS
IPC: A61K38/08
Filed: 1992-12-18
Abstract: The invention relates to the use of bradykinin-antagonists of the formula    R<1> - A - B - C - E - F - G - J - K - R<2>   wherein R<1> represents hydrogen, C1-C4-alkanoyl which can be substituted by mercapto, hydroxyphenyl, (4-benzoyl)phenoxy or represents (4-benzoyl)benzoyl-Lys; A represents D-Arg or D-Lys or stands for a direct bond; B represents Arg which can be substituted by NO2 or toluol-4-sulfonyl or represents Lys which can be substituted by toluol-4-sulfonyl or CO-NH-C6H5, or stands for a direct bond; C represents Hyp-Pro-Gly, Pro-Hyp-Gly, Pro-Pro-Gly or dehydroPro-Hyp-Gly; E represents Thi, Phe, Leu or Cha; F represents Ser or Cys; G represents D-Tic, D-Phe or D-Hyp substituted by C1-C4-alkoxy; J represents Tic, Aoc or Oic; K represents Arg or Ahx or stands for a direct bond; R<2> is hydroxy or amino; and the physiologically tolerable salts thereof for the treatments of acute pancreatitis, to pharmaceutical agents containing them and to the use thereof for the preparation of appropriate pharmaceutical compositions.
Patent FI-932762-A0 (FI)
Inventor: PARK JOHN J
IPC: A01N59/00
Filed: 1993-06-16
Abstract: Compostions, and method useful for making such compositions and for using such compositions, which are useful to destroy hydrogen peroxide in a liquid aqueous medium, such as that used to disinfect contact lenses, are disclosed. The composition comprises at least one item containing a hydrogen peroxide destroying component, e.g., catalase, effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on the at least one item and acting to substantially prevent the release of the hydrogen peroxide destroying component for a period of time after the composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium. The barrier coating comprises a water soluble coating component, e.g., hydroxypropylmethyl cellulose, and is formed by a method which comprises applying a mixture comprising water, a ketone and the water soluble coating component to produce at least one precoated item; and removing water and ketone from the precoated item or items. In a preferred embodiment, the composition includes a cleaning enzyme to remove debris from the contact lens, in particular at the same time the lens is being disinfected.
Patent FI-940031-A0 (FI)
Inventor: KUO ELIZABETH ANNE
IPC: C07D213/84
Filed: 1994-01-04
Abstract: The invention relates to the products <IMAGE>  in which     A, B and E represent =CH- or N with A or B or E = N,   R represents cycloalkyl, alkenyl or alkynyl (>/= C6),   R1 represents H or (C1-3)alkyl, R2 and R3 represent H, Hal, CN, NO2, (C1-6)alkyl, -cycloalkyl, -alkoxy or -alkylthio, -(CH2)m-CX3, -O-(CH2)m-CX3, -S-(CH2) m-CX3, -O-(CX2)m-CX3 or -S-(CX2)m-CX3, m being 0 to 3 and X being halogen, or -COR4, R4 being H, alkyl or cycloalkyl (>/= C3)   or R2 and R3 together form -O-CH2-O-,  as well as to their tautomeric forms and to their salts with bases. The products (I) have advantageous anti-inflammatory properties.
Patent FI-941603-A0 (FI)
Inventor: THEURER JOSEF
IPC: E01B27/00
Filed: 1994-04-07
Abstract: A ballast or track formation working machine (1) for a track (8) formed from rails (6) and sleepers (7) has a machine frame (2) capable of travelling continuously on the track by means of rail running mechanisms (5), and a track-lifting device (15) arranged between two rail running mechanisms and connected height-adjustably to the machine frame (2) by means of drives (37) for lifting the track (8). The track-lifting device (15) is equipped with a supporting body (25) which runs perpendicularly to the machine longitudinal direction, is constructed longer than the length of a sleeper, forms, when in use, with the drives (37) a constructional unit (38) embracing the track (8) in the machine transverse direction and supported solely on the machine frame (2), and is connected to a rolling element (26) - rotatable about an axis oriented in the machine transverse direction - for supporting the sleepers (7) of the track (8). <IMAGE>
Patent FI-942114-A0 (FI)
Inventor: HESSE ROBERT HENRY
IPC: A61P3/02
Filed: 1994-05-06
Abstract: 1-alpha-hydroxy vitamin D3 amide derivs. of formula (I) and (II) and their 20-epi analogues are new. Y = 1-4C alkylene or alkenylene; R1, R2 = H, lower alkyl, cycloalkyl or, together with the N atom to which they are attached, form a heterocyclic gp.; and R3, R4 = H or an O-protecting gp. A typical cpd. is 1 alpha,3 beta-dihydroxy-9,10-seco-25-azacholesta -5(Z),7,10(19)-trien-24-one (Ia).
Patent FI-942450-A0 (FI)
Inventor: REINL HUBERT
IPC: A23L13/60
Filed: 1994-05-26
Abstract: The invention relates to a refrigerated pasteurised spreadable mousse which has a pH between 5 and 6, an aw value between 0.960 and 0.980 and a DM content between 35 and 50% and contains between 20 and 43% nitrogen or air by volume.
Patent FI-953889-A0 (FI)
Inventor: CAMERON PAUL
IPC: B01D33/23
Filed: 1995-08-17
Abstract: A device for filtering liquids has an annular disc (1) with at least one perforated side wall. A plurality of separate sections (14) of a filter medium are applied onto frames (13) and each said section covers a part of the perforated side wall. According to the invention, the separate sections (14) of filter medium are attached to the respective frames (13), such that each section and its frame form a filter unit (12) separate from the perforated side wall, each filter unit being releasably connected to the disc. The filter units can be made light-weight and suitably identical, which facilitates exchange of filter units with defective sections of filter medium for new filter units.
Patent FI-960120-A0 (FI)
Inventor: CHASAN DAVID ELIEZER
IPC: C10N30/10
Filed: 1996-01-10
Abstract: The instant invention relates to a lubricant composition stabilized against the deleterious effects of heat and oxygen. The composition comprises a triglyceride oil or an oil which is an ester wherein unsaturation is present in either the alcohol moiety or the acid moiety and an effective stabilizing amount of either an N,N-disubstituted aminomethyl-1,2,4-triazole or an N,N-disubstituted aminomethylbenzotriazole; a higher alkyl substituted amide of dodecylene succinic acid; a phenolic antioxidant; and an aromatic amine antioxidant. Further additives can be added to these lubricant formulations.
Patent FI-973176-A0 (FI)
Inventor: ROMERO ARTHUR G
IPC: C07C233/11
Filed: 1997-07-31
Abstract: PCT No. PCT/US96/00020 Sec. 371 Date Jun. 20, 1997 Sec. 102(e) Date Jun. 20, 1997 PCT Filed Jan. 16, 1996 PCT Pub. No. WO96/23760 PCT Pub. Date Aug. 8, 1996Compounds and their pharmaceutically acceptable salts suitable for treating central nervous system disorders associated with the dopamine D3 receptor activity of Formula I: wherein R1 and R2 are independently H, C1-8 alkyl or C1-8 alkylAryl; X is CH2R3 or NHSO2R4; Y is hydrogen, CH2R3, NHSO2R4, CONR1R2, SO2NR1R2, SO2CH3, halogen, OSO2CF3, SCH3 or OCH3; R3 is NHSO2R4, SO2R4, CONR1R2 or Aryl; and R4 is NR1R2, C1-C8 alkyl, Aryl or C1-C8 alkylAryl.
Patent FI-974319-A0 (FI)
Inventor: SMITH GALE EUGENE
IPC: C12N/
Filed: 1997-11-25
Abstract: Recombinant influenza haemagglutinin (HA0) expressed in a baculovirus expression system in cultured insect cells is new. Also new is a vector for prodn. of recombinant HA0 comprises, in 5' to 3' sequence, a polyhedrin baculovirus promoter, ATG start codon, signal peptide (SP) sequence, sequence for mature HA0, stop codon and polyhedrin RNA polyadenylation signal.
Patent FI-982430-A0 (FI)
Inventor: LAIJOKI-PUSKA RITVA
IPC: F24F3/00
Filed: 1998-11-09
Abstract: The present invention relates to a spatial structure (1, 1a) arranged especially for spending of leisure, said structure comprising structures (2, 3) defining an interior space (6) separated from the ambient open-air. Several at least partially closed separate spaces (7 to 16b, 23) are arranged in said interior space (6), wherein the climate in each separate space can be separately regulated in accordance with mutually differing conditions. The invention also relates to a method for presenting different climate conditions and especially activities related to the cold season, in which the temperature in functionally interconnected essentially closed separate spaces (7 to 16b, 23) is separately regulated to correspond to the appropriate climate.
Patent IL-69879-A0 (IL)
Title: Process and apparatus for producing foamed synthetic resin bodies
IPC: B29C67/20
Filed: 1983-09-30
Abstract: A porcess for producing a foamed synthetic resin body comprising continuously extruding a foamable thermoplastic resin extrudate composition from an extruder die (2, 3) into a reduced pressure zone (11, 19), subjecting the extrudate (F) to en expansion molding step, a cooling-hardening step and a cutting step while transporting the extrudate through the reduced pressure zone to obtain a foamed piece of predetermined length (F min ), shutting off a portion (19) of the reduced pressure zone surrounding the foamed piece from the other portion thereof when the foamed piece has reached a specified position to restore the foamed piece surrounding portion to a normal pressure, subsequently discharging the foamed piece into the atmosphere, and thereafter bringing the surrounding portion into communication with the reduced pressure zone again upon reducing the pressure. Foamed resin bodies of desired expansion ratio and shape can be prepared continuously with high cooling efficiency. An apparatus for practicing the process is also disclosed. Such apparatus includes means to form a continuous length of extrudate with a vacuum chamber and means to cut the extrudate to length and means to pass (10, 10 min ) the cut extrudate into a second chamber (19), and then to cause the cut length to exit the second chamber (11) without affecting the reduced pressure in the chamber or reduced pressure zone.
Patent IL-72495-A0 (IL)
Title: N-(2-nitrophenyl)-2-aminopyrimidine derivatives,their preparation and their use for the control of harmful micro-organisms
IPC: C07D239/56
Filed: 1984-07-25
Abstract: The invention discloses novel N-(2-nitrophenyl)-2-aminopyrimidine derivatives of the general formula I    <IMAGE>  (I)  wherein R1 and R2 are each independently NO2 or CF3, with the proviso that only R1 or R2 can be NO2  R3 is halogen, R4 is hydrogen or the -C(O)R' group, in which R' is C1-C4alkyl which is unsubstituted or substituted by halogen, C1-C3alkoxy or C1-C3alkylthio, R5, R6 and R7 are each independently hydrogen, halogen, nitro, cyano, thiocyano, C1-C12alkyl, C3-C8cycloalkyl, C1-C8alkylthio, C1-C6alkylsulfonyl, C1-C6alkylsulfoxyl, C3-C6alkenyl, C3-C6haloalkenyl, C3-C6alkynyl, C3-C6haloalkynyl, C3-C6alkenyloxy, C3-C6-haloalkenyloxy, C3-C6alkenylthio, C3-C6alkynyloxy, C3-C6haloalkynyloxy, C1-C8alkyl which is substituted by halogen, cyano and/or C1-C4alkoxy, unsubstituted C1-C8alkoxy or halogen-substituted C1-C8alkoxy, the alkyl moiety of which may be interrupted by one or more single oxygen atoms; or are the Q-(E)n-(X)m-group, in which n is 0 or 1, m is 0 or 1, Q is phenyl which is unsubstituted or substituted by halogen, nitro, C1-C3alkyl, CF3 and/or C1-C3 alkoxy, or is a saturated or unsaturated heterocyclic radical containing one or more hetero atoms, E is a C1-C3alkylene bridge, and X is oxygen or sulfur. Also disclosed are methods of preparing these compounds, and also agrochemical compositions which contain one such compound as active ingredient. The invention further relates to the use of the novel compounds, or, compositions containing them, in agriculture and related fields.
Patent IL-81752-A0 (IL)
Title: Isohexide nucleosides,processes for their preparation and their use as medicaments
IPC: C07F9/6561
Filed: 1987-03-03
Abstract: The invention relates to novel isohexide nucleosides of the general formula I 
<CHEM>
 in which R and B have the meaning given in the description, processes for their preparation and their use as medicaments, in particular as cytostatics, virustatics and immunostimulants.
Patent IL-87560-A0 (IL)
Title: Microencapsulation,process and compositions containing particles prepared thereby
IPC: A01N25/28
Filed: 1988-08-25
Abstract: A process for encapsulating a wide variety of target materials, including both hydrophilic and hydrophobic materials, employs condensation of two reactive compounds to form shells around core phase drops/particles including target mateial dispersed in a continuous phase. One of the reactive compounds has at least two active methylene functional groups per molecule, the other being an active methylene-reactive crosslinking agent. Either type of the reactive compounds can be dispersed in the continuous phase, the other being dispersible in the core phase. Applications include controlled release mocroencapsulation of agriculture chemicals and biocides.
Patent IL-89550-A0 (IL)
Title: Milbemycin derivatives,their preparation and their use as pesticides
IPC: C07H19/01
Filed: 1989-03-09
Abstract: The present invention relates to novel derivatives of formula I that can be derived from milbemycins, to their preparation and their use for controlling pests, and also to pesticides that contain at least one of these compounds as active ingredient. The novel compounds have the general formula I   <IMAGE> (I)  in which X is one of the groups -CH(OR1)-, -C(O)- or -C(=N-OR)-; R1 is hydrogen or an OH-protecting group; R is hydrogen, an OH-protecting group, or an alkyl or cycloalkyl group; R2 is methyl, ethyl, isopropyl or sec.-butyl; and Ph is a phenyl ring that is substituted by Ra, Rb, Rc and Rd, wherein each of Ra, Rb, Rc and Rd, independently of the others, is hydrogen, C1-C10alkyl, C2-C10alkoxyalkyl, C2-C10alkenyl, C1-C10alkoxy, C2-C10alkoxyalkoxy, or a phenyl or phenoxy radical that is unsubstituted or is substituted by at least one substituent from the group C1-C3alkyl and C1-C3alkoxy.
Patent IL-94373-A0 (IL)
Title: Improved process for the preparation of 3,5,6-trichloropyridin-2-ol
IPC: B01J23/72
Filed: 1990-05-13
Abstract: A process for the preparation of 3,5,6-trichloropyridin-2-ol from trichloroacetyl chloride and acrylonitrile is improved by separately conducting the individual addition, cyclization and aromatization steps. By separating these steps, water and HCl, which are by-products of the latter steps, can be precluded from interfering with the earlier steps. The individual process steps have also been improved.
Patent IL-94995-A0 (IL)
Title: Substituted benzonitriles
IPC: A61P3/00
Filed: 1990-07-06
Abstract: Compounds of formula I,   <IMAGE> (I)  wherein Tetr, R, R0, R1 and R2 are as defined in the description, have valuable pharmaceutical properties and are especially effective against tumors. They are prepared in a manner known per se.
Patent AU-PO881797-A0 (AU)
Title: The twin vortex aerator and safety mixer
IPC: C02F3/20
Filed: 1997-08-20
Abstract: A mixing apparatus comprising a central disc driven by a rotating shaft. A number of mixing plates are stacked above and/or below the central disc. The mixing plates are spaced from and parallel to the central disc. Each plate has a central aperture and the diameter of the central aperture increases progressively away from the central disc to define a space coaxial with the rotating shaft. In operation, fluid is drawn into the space and directed out through the space between the plates. When placed near the surface of a fluid, air is drawn in and the fluid is aerated as well as mixed.
Patent AU-PR549901-A0 (AU)
Title: Topical formulation containing tocopheryl phosphates
IPC: A61K47/12
Filed: 2001-06-06
Abstract: The present invention relates to a therapeutic formulation comprising (a) a mixture of at least one mono-electron transfer agent phosphate derivative and at least one di-electron transfer agent phosphate derivative: wherein the amount of mono-electron transfer agent phosphate derivative is no less than equimolar to the amount of di-electron transfer agent phosphate derivative; and (b) a suitable carrier. It further relates to a process for preparing the same.
Patent AU-PS136102-A0 (AU)
Title: Drive mechanism for a track mounted body
IPC: A47B96/00
Filed: 2002-03-26
Abstract: A drive mechanism for a body where the body has a plurality of load bearing and track engaging wheels that allow the body to move back and forth along a track that comprises an actuator attached to the body that is manually or mechanically driven, a non-load bearing drive wheel that is attached with respect to the body so that it engages a stationary surface adjacent the body and a drive coupling mechanism between the actuator and the drive wheel wherein actuation of the actuator causes rotation of the drive wheel which moves the body along the tracks. The invention provides a convenient mechanism of attaching a drive mechanism to a body and to enable easier movement of track mounted bodies.
Patent FI-20030328-A0 (FI)
IPC: G01G23/00
Filed: 2003-03-03
Abstract: The invention relates to a method and to an arrangement (200) for protecting a measuring transducer (202). The invention relates specifically to an arrangement for protecting a measuring transducer (202) from the effect of a measured quantity whose magnitude and/or direction exceeds/goes below a predetermined measuring range. The arrangement comprises a means (102) made at least partly of functional metal, the means (102) being deformed with the aid of a magnetic field generated in connection with the means. When a measurement signal proportional to the effect of the measured quantity exceeds/goes below a predetermined measuring range, the magnetic field and consequently the shape of the means (102) containing functional metal can be varied such that the access of the effect of the measured quantity to the measuring transducer (202) is limited at least partly as a result of deformation of said means (102) containing functional metal, either directly or indirectly.
Patent FI-20075528-A0 (FI)
Inventor: LINDSTROEM MARKO
IPC: E05B/
Filed: 2007-07-09
Abstract: A door lock (1) having a lock body (2) equipped with a front plate (3), said lock body including a hook bolt (4) movable between the locking and released position with a key, the hook bolt being arranged to cooperatewith a striker plate (11) in the door frame so that in its locking position, the hook bolt (4) is pushed into the striker plate opening (11a) and its hook part (6) is turned towards the inner surface of the striker plate (11). The hook bolt (4) comprises a plate-like body part (5) with hook parts (6) pivotably mounted on both sidesthereof, and in the locking position of the hook bolt (4), the body part (5) together with the hook parts (6) extends into the striker plate opening (11a). The body part (5) is furnished with side elements (8) arranged at the positions of the hook parts (6), and in the locking position of the hook bolt (4), the side elements (8) together with the body part (5) and the hook parts (6) are arranged to substantially fill the striker plate opening (11a). Furthermore, in the lengthwise direction of the front plate (3), the body part (5) is dimensioned so that in its locking position, it is wider at the front plateopening (3a) compared to other parts of the hook bolt (4), and the front plateopening (3a) has a separate cutout (3b) for thebody part (5) preferably at both the top edge and the bottom edge of the opening.
Patent FI-20085243-A0 (FI)
Inventor: SO WON WOOK
IPC: H04B/
Filed: 2008-03-25
Abstract: Apparatus and method for removing interference noise in a personal communication terminal. A function of removing interference noise is adapted to the personal communication terminal, and adjustment parameters for removing interference noises are continuously set to up-to-date adjustment parameters, so that, in the activation of broadcast receiving, a turn-on stabilizing time of the personal communication terminal can be reduced, and the broadcast receiving performance can be maintained at an optimum state.
Patent IL-101004-A0 (IL)
Title: Methyldioxolan
IPC: C07F9/50
Filed: 1992-02-18
Abstract: 2R,4S-2-Ethyl-4-[(4-phenoxyphenoxy)-methyl]-dioxolane of the formula I 
<IMAGE>
 which is novel, can be used as a pesticide, preferably for controlling insects in fruit and citrus fruit plantations.
Patent IL-104249-A0 (IL)
Title: Clear axis,segmented multifocal ophthalmic lens
IPC: G02C7/06
Filed: 1992-12-28
Abstract: A multifocal refractive lens to focus light on the retina of the eye. The lens is comprised of a plurality of segments, having different optical powers, at least one for distance vision and another for near. The lens does not require orientation to produce adequate far and near vision and normal stereoscopic effect. One or both of the segments having the optical powers may have aspherical lens surface. The central zone of the lens consists of only one lens segment, providing a clear central axis. Segments of the other optical power border the first segment along a path defined by a semi-circle or hyperbola that extends from one point along the periphery of the adjoining segments to another point along the periphery of the adjoining segments. <IMAGE>
Patent IL-123603-A0 (IL)
Title: Absorbent pair refrigeration system
IPC: H05B6/74
Filed: 1996-09-17
Abstract: An absorbent pair refrigeration system comprising a source of liquid refrigerant (46); an evaporator (48) for transforming the liquid refrigerant into vapor refrigerant at a lower temperature than the liquid refrigerant to thereby provide a desired cooling effect, a volume (52) of absorbent in communication with the evaporator (48), wherein the vapor refrigerant is absorbed onto the absorbent; an electromagnetic wave generator (62) for desorbing the vapor refrigerant from the absorbent without appreciably heating the absorbent; and a condenser (56) in communication with the absorbent for condensing the vapor refrigerant which has been desorbed from the absorbent. <IMAGE>
Patent IL-127137-A0 (IL)
Title: Dibenzo-oxazepine and-dioxepine derivatives and their use as anti-tumor agents
IPC: C07D267/20
Filed: 1997-05-30
Abstract: Compounds of formula (I),    <IMAGE>  (I)  wherein R1 and R2 are independently hydrogen, unsubstituted lower alkyl or lower alkyl substituted by lower alkoxy or lower alkyl thio, or acyl which is unsubstituted or substituted by one or more of lower alkyl, lower alkyl substituted by halogen, and lower alkoxy; X is CO or CHOH; Y is CO or CH2; and Z is O or NH, and epimers and enantiomers thereof, or the physiologically usable salts thereof are useful as anti-tumor agents. They can be prepared by fermentation of Aspergillus sp. and, optionally, subsequent modification of functional groups.