baber/WOPTO huggingface dataset:
Patent CA-2672981-A1 (CA)
Title: Novel gene disruptions, compositions and methods relating thereto
Inventor: VOGEL PETER
IPC: C12N15/85
Filed: 2008-01-22
Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO57290 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as cardiovascular, endothelial or angiogenic disorders; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; or developmental abnormalities.
Patent CA-2674094-A1 (CA)
Title: Process for preparing entacapone substantially free of z-isomer, synthesis intermediates thereof and a new crystalline form
Inventor: PALOMO NICOLAU FRANCISCO EUGENIO
IPC: C07C255/41
Filed: 2008-02-13
Abstract: The present invention relates to a new process for preparing Entacapone substantially free of Z-isomer from 3, 4-dihydroxy-5-Nitrobenzaldehyde and N, N-Dimethylcyano acetamide, or directly from a mixture of (E) - and (Z) - isomers of Entacapone, by formation of organic or inorganic salts, specially piperidine and sodium ones. A new crystalline form G of Entacapone can be obtained from this method in a fast, efficient, and simple way and substantially free of Z-isomer. Another object of the invention is a pharmaceutical composition comprising it.
Patent CA-2674112-A1 (CA)
Inventor: TUMELTY DAVID
IPC: C07K14/605
Filed: 2008-01-07
Abstract: The present invention provides glucagon-like protein 1 receptor targeting compounds which, comprise glucagon-like protein 1 receptor targeting agent-linker conjugates linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
Patent CA-2674174-A1 (CA)
Title: Composition pour adhesif structural
Inventor: DAVID REGIS
IPC: C09J153/00
Filed: 2007-12-24
Abstract: L'invention se rapporte à une composition pour adhésif structural acryliq ue contenant un mélange de copolymères blocs contenant du styrène et d élast omère.
Patent CA-2674955-A1 (CA)
Inventor: ORAL EBRU
IPC: C08F2/46
Filed: 2008-01-25
Abstract: The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (.alpha.-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (.alpha.-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.
Patent CA-2679133-A1 (CA)
Title: A method of applying a non-voc coating
Inventor: KOETZLE RICHARD A
IPC: C09D7/80
Filed: 2007-02-27
Abstract: A method for applying a coating meeting a predetermined volatile organic compound (VOC) standard. The compound functions as a coating and plasticizer. The inventive method involves mixing acetone and terpene alcohol, or terpineol, to form a solvent system with a flash point of at least 140 °F. A resin is solubilized into the solvent system and forms a coating. The coating is cast over substrate surfaces to cure and dry. The solvent system produced by the inventive method can also be used in other applications including as a cleaning composition.
Patent CA-2680029-A1 (CA)
Title: Aminopyrimidines useful as inhibitors of protein kinases
Inventor: HENKEL GREGORY
IPC: A61K31/506
Filed: 2008-03-10
Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
Patent CA-2682638-A1 (CA)
Inventor: SANA FELIX
IPC: A61K9/16
Filed: 2008-03-18
Abstract: The present invention relates to a method of forming granules of (2R,3S,4R,5R)-5-(4-amino-2-oxo-2 H -pyrimidin-1-yl)-2-azido-3,4-bis -iso-butyryloxy-tetrahydro-furan-2-ylmethyl isobutyrate; hydrochloride salt (I), comprising mixing I, with a granulating amount of a granulating liquid, and a polyethylene glycol (PEG)/polypropylene glycol (PPG) block copolymer as a binder and solubility enhancer to form wet granules which are then dried to remove the granulating liquid.
Patent CA-2683281-A1 (CA)
Title: Method and transmission device with adaptation of the coding data to the channel data
Inventor: ZUREK-TERHARDT GUENTHER
IPC: H04N7/52
Filed: 2007-12-17
Abstract: The invention relates to a method and a transmission device for transmitting program data or service data, and for coding data for coding the program or service data in periodically repeated burst intervals corresponding to each program or service (A, B) in a digital television transmission system which has an adjustable ratio of the quantity of the program or service data for each program or service (A, B) to the quantity of the corresponding coding data, to the program data or service data belonging to individual programs or services (A, B) divisible into multiple subquantities of program or service data, and wherein said digital television transmission system has for each subquantity a different adjustable ratio of the quantity of program or service data to the quantity of corresponding coding data at constant length (.DELTA.tA; .DELTA.tA', .DELTA.tA'; .DELTA.tA1, .DELTA.tA2, .DELTA.tA3, .DELTA.tA4) of the corresponding burst interval of the corresponding program or service (A, B).
Patent CA-2683417-A1 (CA)
Title: User programmable hearing assistance device
Inventor: SCHUMAIER DANIEL R
IPC: H04R25/00
Filed: 2008-04-23
Abstract: A programmable apparatus improves perception of sound by a person. The apparatus includes a processor, digital-to-analog converter, audio output section and means for generating first and second control signals. The processor executes one or more available programs for processing digital audio signals based on control signals. The digital-to-analog converter generates output analog audio signals based on the digital audio signals. The audio output section receives and amplifies the output analog audio signals, generates audible sound based thereon and provides the audible sound to the person. The memory stores programs for processing the digital audio signals. Based on an action by the person, a first control signal is generated which causes the processor to switch from one available program to another available program so that the person may cycle through and evaluate each of the available programs. Also based on an action by the person, a second control signal is generated which causes the processor to designate at least one of the available programs as a chosen program for continued use. The apparatus may include a counter that counts the number of times that power is applied to or removed from the apparatus. After a predetermined elapsed time, the processor determines which of the available programs has been used most in processing the digital audio signals, where the determination of elapsed time is based at least in part on the counter value.
Patent CA-2684244-A1 (CA)
Inventor: HOJAJI HAMID
IPC: C04B14/16
Filed: 2008-04-16
Abstract: Low density additives and methods of making said additives for composite materials are provided. The low density additives have at least a partial or complete water repellant property that reduces moisture migration, absorpti on, and retention within a composite material in which it is incorporated in to. Active sites are engineered onto the surface of the low density additive s to enhance bonding of the additives within a composite matrix. Reduced wat er movement and enhanced bonding lead to an increased strength and durabilit y performance for a composite material comprising such additives. Composite materials incorporating one or more engineered low density additives as also provided, such composite materials having enhanced strength and durability. Such composite materials may be made from a Hatschek process. The composite materials may be further used as interior and exterior building products.
Patent CA-2684723-A1 (CA)
Title: Collapsible storage bin
Inventor: STUKENHOLTZ JAY
IPC: A01D90/02
Filed: 2008-04-23
Abstract: An agricultural vehicle such as a combine is provided with a collapsible agricultural material storage bin. The bin may be collapsed to allow for decreased overall vertical height during transport to avoid contact with obstacles, such as overhead power lines and street lights. In the field, the agricultural material storage container may be expanded to increase the agricultural material holding capacity of the vehicle. The bin may be provided with an internal extension mechanism to increase the lifting power of the container to allow for the placement of a second container or other material thereabove. Alternatively, the container may be provided with an external lifting means to allow for unobstructed evacuation of the interior of the container.
Patent CA-2686007-A1 (CA)
Title: Auxiliary vacuum device for a central vacuum cleaning system
Inventor: MARCIL CHRISTIAN
IPC: A47L9/24
Filed: 2009-11-23
Abstract: An auxiliary vacuum device for a central vacuum cleaning system is location specific and comprises housing mountable externally on an inlet of a mounting plate of the system, a dedicated flexible concertina hose is provided on the device and a cleaning tool mounting probe is registrable with a docking station.  When the probe is removed from the docking station, a lever may be moved in first and second directions to selectively activate and deactivate the motor of the central vacuum cleaning system and the device. When the probe is parked in the docking station the probe moves the lever in one of the directions and holds the lever in a deactivated configuration, thus deactivating the motor and the device and preventing activation thereof.
Patent CA-2686025-A1 (CA)
Title: Cage spacer with roller wheel
Inventor: VERELLI ANGELO
IPC: E04C5/18
Filed: 2009-11-18
Abstract: A cage spacer for spacing a reinforcement structure apart at a predefined distance from a forming surface of a forming structure for a cementitious structure during formation of the cementitious structure therein has a bracket and a roller wheel, both constructed of a plastic material. The bracket has an attachment face and a generally opposed roller face and is connectable to the reinforcement structure with the attachment face abutting thereagainst. The roller wheel is rotatably and removably mounted in the bracket with an outer circumferential surface thereof extending from within the bracket partially beyond the roller face. The roller wheel is sized and positioned relative the attachment face for abutting and rolling of the outer circumferential surface against the forming surface at the predefined distance from the reinforcement structure, thereby spacing the reinforcement structure apart from the forming surface at the predefined distance.
Patent CA-2686151-A1 (CA)
Inventor: JOHNSON FREDERICK M
IPC: H04N21/6332
Filed: 2007-05-03
Abstract: A system and method for managing, routing and controlling devices and inter-device connections located within an environment to manage and control the environment using a control client is presented. A user provides commands via the control client to a server that maintains a representation of the environment and the devices within the environment. The server provides commands to devices present within the environment in response to user commands and other events, including events from the environment. The commands cause the devices in the environment to adopt specific desired states thereby causing the environment and the devices within the environment to create desired connections by and between the devices and to otherwise control and effect the environment.
Patent CA-2686345-A1 (CA)
Inventor: STEPHENSON DARYL
IPC: A24F25/02
Filed: 2008-05-29
Abstract: A humidifier (10) for use with tobacco products comprises a first container (12) permeable to the passage of water vapour and configured to enclose a moisture-releasing element (14) that emits water vapour, a second container (18) arranged for thermal energy transfer to the moisture-releasing element, the second container having sealed therein a supercoolable salt hydrate solution and an activating device (22) actuable to initiate crystallisation of the salt hydrate solution, thereby releasing heat, and supplying it to the moisture-releasing element. The heating increases 'the rate of evaporation from the moisture-releasing element, thereby quickly providing water vapour to hydrate tobacco.
Patent CA-2691050-A1 (CA)
Inventor: DESMARAIS ANDRE
IPC: B62D53/08
Filed: 2010-01-29
Abstract: A protective safety cover for fifth wheel pin has a main panel having at least one edge, and an opening adapted to receive the king pin of the trailer therethrough; a perimeter wall extending perpendicularly to the at least one edge of the main panel; and a retainer member connected to the main panel and adapted to securely and removably attach the safety cover to the goose neck of the trailer and around the king pin, to thereby surround the king pin and protect a person from accidentally hitting the king pin.
Patent CA-2691133-A1 (CA)
Inventor: VAN DER BIJL WILLEM MEES
IPC: B60N2/48
Filed: 2008-06-12
Abstract: Seat to accommodate a child in a vehicle, the seat being adapted for secure connection to the vehicle e.g. to a conventional forward facing vehicle seat for an adult; the seat having a support portion (10) on which a child may sit, a rear portion (11) configured to restrict movements of the back of the child, and a headrest (12) configured to restrict movements of the back of the head of the child, in which a first upright member (15) is connected to a rear part of [or a rear extension to] the support portion (10) and a second upright member (16) is connected to a rear part of [or a rear extension to] the headrest (12), the upright members (15 and 16) being parallel to each other, and in which there is adjustment means to adjust the relative position of the headrest with respect to the support portion, the adjustment means comprising a rotary member (19) rotatable about a horizontal axis fixed with respect to the rear portion (11), the rotary member (19) having grips (27, 28) at its ends projecting sideways from the support portion within or behind the support portion and projecting detents (21,22) between the grips, the detents (21, 22) being arranged to engage facing slots (15a and 16a) of identical pitch apart in the first and second upright members, the arrangement being such that when the rotary member (19) is turned by the grips (27, 28), the rear portion (11) is raised by the pitch of the slots (15a and 16a), and the headrest (12) is raised by twice the pitch of the slots.
Patent CA-2694488-A1 (CA)
Inventor: WU HERREN
IPC: C07K16/46
Filed: 2008-07-30
Abstract: The present invention relates to multispecific epitope binding proteins, methods of making, and uses thereof in the prevention, management, treatment or diagnosis of acute or chronic diseases.
Patent CA-2696310-A1 (CA)
Inventor: QUANDT JACQUELINE A
IPC: A61P19/00
Filed: 2008-08-13
Abstract: Disclosed is a method of treating a disease involving myelin and/or axonal loss, such as a demyelinating disease, in a mammal comprising administering a compound of formula I, in which R1-R11 and n are defined herein. Also disclosed are methods of using a compound of formula 1 to treat neurodegeneration associated with inflammation and to reduce myelin and/or axonal loss.
Patent CA-2697571-A1 (CA)
Title: High temperature additive manufacturing systems for making near net shape airfoil leading edge protection, and tooling systems therewith
Inventor: PERETTI MICHAEL W
IPC: C23C4/04
Filed: 2010-03-23
Abstract: A high temperature additive manufacturing system (29) comprising a high temperature additive manufacturing device (38) for providing a metallic deposit (40); and a tooling system (30) comprising: a mandrel (32) for receiving, and providing shape to, the metallic deposit (40); a metallic cladding (34) applied to the mandrel (32) for reducing contamination of the metallic deposit (40); and at least one cooling channel (36) associated with the mandrel (32) for removing heat from the system (30).
Patent CA-2698279-A1 (CA)
Inventor: SURRENA BRADEN
IPC: A01N25/22
Filed: 2010-03-31
Abstract: The present disclosure provides fungicidal compositions and methods of enhancing vegetation, e.g. turfgrass. The composition may be a combination of chlorothalonil and malachite green dye. Malachite green oxalate is preferred. This composition is mixed with water and inert ingredients such as surfactants and other inert ingredients. A  phonosphonate compound may be added, such as a phosphite. Potassium phosphite may be used.  Urea phosphite is preferred. The composition is mixed in water with inert ingredients such as surfactants and other inert ingredients.
Patent CA-2700350-A1 (CA)
Inventor: LOMBARDINI FRANCESCO
IPC: B65H19/22
Filed: 2008-10-08
Abstract: A winding system for use in plastic films production lines comprising a plurality of winders (11-13) constrained to a star- shaped winder holder (10) rotatable around its own axis, said winders (11-13) being arranged around said star- shaped winder holder (10) in such a manner that at least one first winder (11) of said plurality of winders is arranged at an operating position for winding a film (18) to form a reel (19), characterised in that associated to said at least first winder (11-13) are contact means (26-28) moveable between a first position of contact with said reel (19) to wind on said first winder (11-13) and a second position distal from said reel (19), said contact means (26-28) being further preferably rotatable around said axis of said star- shaped winder holder (10) with the aim of maintaining said first position in contact with said reel (19) when said first winder (11-13) is moved away from said winding position.
Patent CA-2701069-A1 (CA)
Title: Apparatus and method for detection of an analyte in a sample
Inventor: DELAMARCHE EMMANUEL
IPC: B81C1/00
Filed: 2008-10-30
Abstract: There is provided an apparatus for the detection of an analyte in a sample.  The apparatus comprises at least a first measurement channel (2a) comprising a detection reactant (3) corresponding to the analyte (4) to be detected, and at least a microstructure (5) associated with the first measurement channel (2a). When the apparatus (1 ) is in use, the sample is introduced into the first measurement channel (2a) and propagated by way of the first measurement channel (2a) towards the microstructure (5) such that the analyte (4), if it is present in the sample, interacts with the detection reactant (3) to form a networked product (6), and the microstructure (5) is configured to filter the networked product (6).
Patent CA-2701407-A1 (CA)
Inventor: DOTTORI FRANK A
IPC: C08H8/00
Filed: 2010-04-23
Abstract: A process is defined for the continuous steam pretreatment and fractionation of corn cobs and low lignin lignocellulosic biomass to produce a concentrated cellulose solid stream that is sensitive to enzymatic hydrolysis. Valuable chemicals are recovered by fractionating the liquid and vapor stream composed of hydrolysis and degradation products of the hemicellulose. Cellulosic derived glucose is produced for fermentation to biofuels. A hemicellulose concentrate is recovered that can be converted to value added products including ethanol.
Patent CA-2705326-A1 (CA)
Inventor: VINING DAVID J
IPC: A61F2/958
Filed: 2008-11-11
Abstract: An apparatus and method are provided for use in administering a rectal contrast enema to a patient to prepare the patient for a medical procedure. A rectal catheter may be provided to facilitate administration of the enema preparation to the patient. The rectal catheter may include a retention balloon. A  delivery mechanism may be provided to urge the enema preparation into the patient. A vacuum may be provided to remove waste from the patient. A gas insufflator may be provided to insufflate the patient's colon for a medical procedure such as a scan, and more specifically, a virtual colonoscopy.
Patent CA-2707595-A1 (CA)
Inventor: DUFILHO PAUL WILLIAM
IPC: B07B1/46
Filed: 2008-12-11
Abstract: A screen assembly for a vibratory separator, the screen assembly comprising a screen support (12) having at least one side forming a perimeter, a t least one layer of screening material (14) supported thereby, and a seal member (20) characterised in that said seal member (20) comprises a side portion (22) encompassing said perimeter of said sup port (12), and a sealing portion (24,26) extending underneath said screen support (12).
Patent CA-2707618-A1 (CA)
Inventor: BLADH HAKAN
IPC: A61K31/58
Filed: 2008-12-18
Abstract: The present invention provides compounds of formula (I) wherein n, p, R1, R2, X1, X2 , X3 R3a R3b R4, R5 and R6 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.
Patent CA-2708081-A1 (CA)
Title: Curable benzoxazine-based compositions, their preparation and cured products thereof
Inventor: KREILING STEFAN
IPC: C08K3/00
Filed: 2008-12-02
Abstract: The invention relates to a curable composition comprising: at least one benzoxazine and at least one toughening additive which can be bound to the at least one benzoxazine in the curing process, characterized in that the toughening additive is distributed in the cured composition in form of discrete domains, and that at least 50% of the discrete domains related to the total amount of discrete domains having a maximum length in any direction of space in the range of 10 nm to 500 nm as determined by transmission electron microscopy (TEM).
Patent CA-2711108-A1 (CA)
Inventor: ROBINSON TIMOTHY MARK
IPC: A61L15/58
Filed: 2009-02-27
Abstract: Provided herein is a system and method for facilitating removal of a drape from a tissue site.  One aspect provides a system comprising a drape, and adhesive layer, and a release agent, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimu-lus. Another aspect provides a method for application and removal of a drape using less force than re-quired with a conventional drape.
Patent CA-2711846-A1 (CA)
Inventor: GONCALVES DA SILVA DENIVALDO
IPC: A45D8/30
Filed: 2008-06-09
Abstract: 'HAIR-CLIPPER', the proposal of such Inventive Disposition Introduced in Hair-clipper is a Patent of Utility Model being composed by variations of style that will be able to give professionals easiness and options on hair holding, the hair-clipper now referred innovates as to making its use easier and giving options on hair holding way efficiently, irrespectively of the hair volume, amount or thickness, and whether the hair is straight, curly, thin or thick.