baber/WOPTO huggingface dataset:
Patent NZ-526072-A (NZ)
Title: Treatment of phencyclidine addiction and PCP addiction-related behaviour with gamma vinyl GABA ( GVG )
Inventor: DEWEY STEPHEN L
IPC: A61K31/135
Filed: 2001-03-07
Abstract: Gamma vinylGABA (GVG), gabapentin, topiramate, progabide, fengabine, gamma-hydroxybutyric acid is used in the manufacture of a medicament for changing addiction-related behaviour of a mammal suffering from PCP addiction, wherein the medicament acts to diminish, inhibit or eliminate behaviour associated with craving or use of PCP and attenuates the rewarding/incentive effects of PCP in the absence of altering rewarding/incentive effects of food and drugs
Patent NZ-528107-A (NZ)
Title: Metalloproteinase inhibitors
Inventor: MUNCK AFROSENSCHOLD MAGNUS
IPC: A61P25/02
Filed: 2002-03-13
Abstract: Compounds of formula I and pharmaceutical preparations containing such compounds are disclosed.
Patent NZ-530992-A (NZ)
Title: Heteroaryl substituted fused bicyclic heteroaryl compounds as GABAA receptor ligands
Inventor: HUTCHISON ALAN
IPC: A61P25/22
Filed: 2002-07-12
Abstract: Heteroaryl substituted fused bicyclic heteroaryl compounds, such as heteroaryl substituted imidazopyridines, imidazopyrazines, imidazopyridizines, imidazopyrimidines, and imidazothiazoles, which may be described by Formula (I) or Formula (II) are disclosed, wherein these compounds bind with high selectivity and high affinity to the benzodiazepine site of GABAA receptors. Pharmaceutical compositions comprising such compounds and to the use of such compounds in treatment of certain central nervous system (CNS) diseases, as well as processes for preparing compounds of Formula (I) and Formula (II) are also disclosed. Further the use of benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds of Formula (I) or Formula (II) in combination with one or more other CNS agents to potentiate the effects of the other CNS agents, and the use of such compounds as probes for the localization of GABAA receptors in tissue sections is also described.
Patent NZ-531721-A (NZ)
Title: Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
Inventor: GUO HONG
IPC: A61F9/007
Filed: 2001-04-19
Abstract: Disclosed is a multilayered drug delivery device 100 which includes a drug reservoir 114 containing a quantity of a drug to be slowly released. An inner tube 112 surrounds the reservoir and is in turn covered with a permeable outer layer 110. The inner tube 112 is made from a polymer material that retains structural integrity during the drug diffusion, allowing the diffusion area and rate to remain constant. (62) Divided out of 522002
Patent NZ-532404-A (NZ)
Title: Method for producing douglas-fir somatic embryos in an initiation medium comprising maltose and/or glucose as the principal carbohydrate source
Inventor: GUPTA PRAMOD K
IPC: A01H4/00
Filed: 2004-04-20
Abstract: Methods for providing Douglas fir somatic embryos are provided. The methods comprise the step of culturing Douglas fir explants in, or on, an initiation medium comprising a principal carbohydrate source selected from the group consisting of maltose, glucose, and a combination thereof, to form embryonal suspensor masses comprising early-stage somatic embryos. Additionally, methods comprise the step of culturing Douglas fir embryonal suspensor masses in a maintenance medium comprising a principal carbohydrate source selected also from the group consisting of maltose, glucose, and a combination thereof, to form an established embryonal suspensor mass comprising early-stage somatic embryos
Patent NZ-542844-A (NZ)
Title: Multi-carbide material manufacture and use
Inventor: DOBBS ROBERT
IPC: C01B32/949
Filed: 2004-03-10
Abstract: Disclosed is a method for milling a product in a media mill, comprising the step of milling a product in a media mill using grinding media, wherein the grinding media comprise a multi-carbide material which includes carbon and at least two carbide-forming metal elements. Also disclosed is a milling apparatus comprising: a media mill; and grinding media used in the media mill to mill a product, wherein the grinding media are shaped suitable for milling the product in the medial mill, and the grinding media comprise a multi-carbide material which includes carbon and at least two different carbide-forming metal elements.
Patent NZ-550665-A (NZ)
Title: Novel water-soluble prodrugs of camptothecin derivatives
Inventor: UMEDA ISAO
IPC: A61K31/519
Filed: 2005-04-08
Abstract: Disclosed are water-soluble camptothecin prodrugs as represented by formula (2) or (3), or a pharmaceutically acceptable salt, or a hydrate or solvate thereof, wherein in Formula (2), R1 represents a hydrogen atom or an alkyl group; X represents a C=O or an alkylene group; R2 and R4 each independently represents a hydrogen atom, an alkyl group, or an amino acid side chain; and R3 represents an alkyl group; wherein in Formula (3), R1 is defined as in formula (2); n represents an integer from 1 to 6; and R5 represents a hydrogen atom or COOR6 (wherein R6 represents a hydrogen atom or an alkyl group); wherein in Formula (2) and (3), Y is a group represented by formula (5): and the other substituents are as defined herein. Also disclosed is a therapeutic agent for a cell proliferation disorder (such as colorectal cancer, lung cancer, breast cancer, gastric cancer, uterine cervical cancer, bladder cancer or a solid tumor) which comprises the water-soluble prodrug as defined above as an effective ingredient.
Patent NZ-551857-A (NZ)
Title: Inactivation of a pathogen in a sample by a treatment with formalin and UV light
Inventor: REITER MANFRED
IPC: A61M1/36
Filed: 2005-05-26
Abstract: A method for inactivating a virus contained in a sample, the method comprising the steps of: (i) treating the sample with an effective concentration of formalin, and (ii) subjecting the sample with an effective dose of UV light in a flow-through apparatus, and (iii) determining the residual infectivity of the inactivated virus in the sample using a mammalian cell safety test comprising the steps of: a) Inoculating a mammalian cell culture with a purified inactivated enveloped virus. b) Incubating the cell culture. c) Harvesting the cell culture and inoculating a second mammalian cell culture with the harvest. d) Incubating the second cell culture. e) Harvesting the second cell culture and testing the harvest for hemagglutinin activity; Wherein step (i) is performed prior to step (ii) or vice versa.
Patent NZ-552094-A (NZ)
Title: Printing material container, and board mounted on printing material container
Inventor: ASAUCHI NOBORU
IPC: B41J2/175
Filed: 2006-12-15
Abstract: A printing material container is detachably attachable to a printing apparatus having a plurality of apparatus-side terminals. The printing material container comprises a first device, a second device, and a terminal group that includes a plurality of first terminals, at least one second terminal and at least one third terminal. The plurality of first terminals are connected to the first device and respectively include a first contact portion for contacting a corresponding terminal among the plurality of apparatus-side terminals. The at least one second terminal is connected to the second device and includes a second contact portion for contacting a corresponding terminal among the plurality of apparatus-side terminals. The at least one third terminal is for the detection of shorting between the at least one second terminal and the at least one third terminal and includes a third contact portion for contacting a corresponding terminal among the plurality of apparatus-side terminals. The at least one second contact portion, the plurality of the first contact portions, and the at least one third contact portion are arranged so as to form one or multiple rows. The at least one second contact portion is arranged at an end of one row among the one or multiple rows.
Patent NZ-552979-A (NZ)
Title: Indane and tetralin derivatives which potentiate glutamate receptor and uses thereof in medicine
Inventor: BRADLEY DANIEL MARCUS
IPC: C07D231/12
Filed: 2005-08-05
Abstract: Disclosed is a compound of formula (I), or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein n is 1 or 2, p is 0, 1, or 2, and wherein the substituents are as defined in the specification. Also disclosed is a process for preparing the compound and it use in treating diseases or conditions caused by a reduction or imbalance in glutamate receptor function, such as schizophrenia.
Patent NZ-555201-A (NZ)
Title: Optical fiber cable with fiber receiving jacket ducts
Inventor: FITZ JONATHAN
Filed: 2005-11-15
Abstract: An optical fiber cable 1 having a length and a longitudinal axis, the cable 1 comprising: a longitudinal strength member disposed at the axis; a tubular plastic jacket 5 encircling the strength member and having a circumferentially continuous outer portion, wherein the strength member and the jacket 5 define at least one longitudinal duct between the jacket 5 outer portion and the strength member, and wherein the jacket 5 includes connecting portions only at circumferentially opposite sides of the duct which provide connections to the strength member; wherein the connecting portions provide connections to the strength member which resist longitudinal movement of the connecting portions with respect to the strength member when the cable 1 is subjected to pulling forces directed parallel to the axis of the cable 1 but which connections can be interrupted by manual forces applied to the jacket 5 and directed radially of the axis; wherein there is at least one longitudinally extending optical fiber 6 in the at least one duct; and wherein the optical fiber in the duct is exposed upon the interruption of the connection of the jacket 5 to the strength member at either of the circumferentially opposite sides of the duct.
Patent NZ-556672-A (NZ)
Title: Improvements in or relating to a carrier
Inventor: PEARSON LEON ROBERT GEOFFREY
IPC: F16M11/00
Filed: 2007-07-24
Abstract: A carrier including a pair of spaced apart pins or arms, the separation of the pins or arms being such that a fencing standard of the type having a loop at one end and a slot at the other end, and having a longitudinal axis may, in use, be engaged with each pin or arm such that one pin or arm engages in the loop of the fencing standard and the other pin or arm engages in the slot of the fencing standard. The pins or arms are of a length such that the carrier may carry a plurality of such fencing standards in a manner such that movement of the fencing standard along the longitudinal axis thereof is limited by the pins or arms.
Patent NZ-567838-A (NZ)
Title: Apparatus for inspecting a container sidewall contour
Inventor: JUVINALL JOHN W
IPC: G01B11/24
Filed: 2006-11-17
Abstract: An apparatus for inspecting contour of a container sidewall is disclosed. The apparatus includes means for rotating the container around an axis, at least one light source, and an information processor. The light source directs light energy onto the container sidewall as the container is rotated around an axis. The light sensor is disposed to receive light energy from the light source reflected from an outside surface of the container sidewall. The light sensor is responsive to the reflected light energy to provide signals indicative of position of the container sidewall relative to the sensor at a first location adjacent to the container shoulder, a second location adjacent to the container heel and a third location between the first and second locations. The information processor is coupled to the sensor and is responsive to the signal for determining contour of the container sidewall in the direction of the axis as the container is rotated around the axis as a function of departure of sidewall position at the third location from a line between sidewall positions at the first and second locations.
Patent NZ-568367-A (NZ)
Title: Treatment of malignant neoplasias using non-radioactive 3-iodo-L-phenylalanine or 4-iodo-L-phenylalanine
Inventor: SAMNICK SAMUEL
IPC: A61K31/198
Filed: 2006-11-27
Abstract: The use of 3-iodo-L-phenylalanine or 4-iodo-L-phenylalanine for treating malignant neoplasia wherein the iodo-L-phenylalanine does not include the [131]-iodine isotope. The iodo-phenylalanine is used to provide a radiosensitizing effect, cytostatic effect and/or an effect to revert an acquired or constitutive state to cellular resistance to chemotherapy or radiotherapy. In a preferred embodiment the iodo-L-phenylalanine is used to treat malignant glioma, multiple myeloma, malignant melanoma, prostatic and breast cancer. The preferred iodine isotope is the stable non-radio-active [127]-iodine isotope.
Patent NZ-570492-A (NZ)
Title: Combination of alpha-2 receptor agonist (clonidin) and an anti-muscarinic agent (oxybutynin) for the treatment of excess salivation or drooling
Inventor: GOLDSMITH PAUL
IPC: A61K45/06
Filed: 2007-02-12
Abstract: A product comprising an alpha-2-adrenoreceptor agonist selected from clonidine, apraclonidine, brimonidine, rilmenidine, dexmedetomidine, tizanidine, monoxidine and lofexidine and the anti-muscarinic agent oxybutynin, as a combined preparation for separate, simultaneous or sequential use in the treatment of sialorrhoea. Said alpha-2-adrenoreceptor agonist is preferably formulated as a gum, spray, pastille, lozenge or dispersible tablet, which may be administered by the paralingual, sublingual or buccal route.
Patent NZ-571113-A (NZ)
Title: Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
Inventor: LYNCH SAMUEL
IPC: A61L27/12
Filed: 2006-11-17
Abstract: Disclosed is the use of a biocompatible matrix in the manufacture of a medicament for enhancing bone augmentation at a desired site in a subject wherein the biocompatible matrix comprises a deproteinized bone block having disposed therein platelet derived growth factor (PDGF).
Patent NZ-580234-A (NZ)
Title: Modular footing system
Inventor: SINGER CHRIS
IPC: E04B1/00
Filed: 2009-10-08
Abstract: This discloses a modular footing system 10 for use with a module or structure, which includes a number of rectangular frames 12 14 16 18 with coupling members 26 22 to removably fix adjacent frames to each other. At least one of the frames includes a space able to receive a block member 30 32 34 that provides weight, the block member 30 32 34 being received substantially within that space.
Patent NZ-582410-A (NZ)
Title: Stand-up unit with a support and a standup mount articulated to the support
Inventor: HUNZIKER KURT
IPC: A61G5/14
Filed: 2008-05-15
Abstract: A stand-up unit (10) comprises a support (21), a stand-up frame (13), which is articulated on the support (21) and has a seat carrier (23) carrying a seat (17), and a backrest carrier (25) carrying a backrest (19). Furthermore, a first lever parallelogram (27) is provided in order to maintain the backrest (19) upright in any position. The backrest (19) can be displaced by the first lever parallelogram (27) by means of a rod (30), in order to ensure that no undesirable relative movement occurs between the backrest (19) and the back of the user when getting up or sitting down. The first lever parallelogram (27) has a first double-armed parallelogram lever (41) and a second double-armed parallelogram lever (49), where the arms (43, 53) of the two double-armed parallelogram levers (41, 49) form a second lever parallelogram (29) with two further levers (55, 57). The common pivot point (35) of the two lever parallelograms (27, 29) is connected in an articulated manner to a first point (44) of the support (21) via a further lever , and the common pivot point (38) of the aforementioned two further levers (55,57) of the second parallelogram (29) is connected in an articulated manner to a second point of the support (21).
Patent NZ-583403-A (NZ)
Title: High yield method of producing pure rebaudioside A
Inventor: JACKSON MEL CLINTON
IPC: A23L25/00
Filed: 2005-10-18
Abstract: Provided is a method of determining the reflux solvent with which to purify rebaudioside A from a starting material selected from the group consisting of Stevia starting material, a crude extract of Stevia plant material, and a crude extract of Stevia plant material which extract has at least 40% rebaudioside A purity, comprising: preparing a series of test mixtures comprising an alkanol mixed with water, the starting material, and optionally one or more denaturants, wherein the water content of the series of test mixtures is increased from a minimum water content that is ten percent or less to a maximum water content that is no more than fifteen percent, refluxing each of the test mixtures, collecting separately by filtration the precipitate of each reflux, washing the precipitate of each reflux in an alkanol that optionally contains one or more denaturants, collecting separately by filtration the retentate of each wash, optionally repeating one or more times the steps of washing and collecting retentate of each wash; optionally drying the retentate of each wash; determining the rebaudioside A yield, purity, or yield and purity of each retentate with reference to the water content of the text mixture from which the retentate was obtained, wherein the series of determinations corresponding to the series of test mixtures is called the water content-yield-purity relationship for the alkanol, starting material, and optional denaturants used in the test mixtures, and examining the water content-yield-purity relationship and selecting the water content of the reflux solvent with which to produce a desired yield or purity of rebaudioside A from the starting material by interpolating between water contents used in the test mixtures, by extrapolating from the water contents used in the test mixtures, or by selecting a water content used in one of the test mixtures.
Patent NZ-592834-A (NZ)
Title: System and methods for a self-healing grid using demand side management techniques and energy storage
Inventor: WILLIAMS BRADLEY R
IPC: G05B1/02
Filed: 2006-11-07
Abstract: A method and a computer program for power grid control are disclosed. The method comprises monitoring electrical characteristics, including critical electrical components, of a plurality of islands of a power grid; estimating state and topology of the islands with the monitored electrical characteristics through computer simulation of power flow through the power grid; detecting an irregularity in an affected island based on the estimated state and topology; and optimizing electrical power delivery to each island based on the estimated state and topology, or in response to the detected irregularity, by automatically adjusting the amount of additional power available through a battery energy storage system in electrical communication with the affected island.
Patent NZ-592937-A (NZ)
Title: A clamp and wrapping assembly for patching a pipe rupture
Inventor: ROBINSON JEFFERY
IPC: F16L55/17
Filed: 2009-11-19
Abstract: A clamp that can be used for repairing a rupture in a pipe. The clamp includes a wrapping assembly (20) comprising strapping (21) that at least partially extends about the pipe, an adjustment device in form of a clasp (22) for adjusting the effective length of the strapping about the pipe and a tensioning device in the form an over centre lever mechanism (23) that is operable to place the wrapping assembly under different tensions.
Patent NZ-596200-A (NZ)
Title: Intravenous formulation with water-soluble cocrystals of acetylsalicylic acid and theanine
Inventor: BRITTAIN HARRY G
IPC: A61K31/60
Filed: 2009-06-23
Abstract: A water-soluble aspirin-theanine cocrystal composition which includes a quantity of acetylsalicylic acid and a quantity of a theanine enantiomer or carbohydrate or amino acid derivative thereof associated with the quantity of acetylsalicylic acid. The composition may be created by a method including the steps of : (i) providing a quantity of acetylsalicylic acid; (ii) adding a quantity of a theanine enantiomer to the quantity of acetylsalicylic acid to form a mixture comprising the quantity of acetylsalicylic acid and the enantiomer of theanine; (iii) wetting the mixture; and (iv) grinding the mixture for a length of time sufficient to produce a dried crystalline mass. The water-soluble cocrystal composition is suitable for intravenous administration, preferably to humans.
Patent NZ-600333-A (NZ)
Title: Use of alpha 2 adrenergic receptor agonists for treating or preventing psoriasis
Inventor: DEJOVIN JACK A
IPC: A61K31/135
Filed: 2010-11-18
Abstract: The disclosure relates to the use of an alpha-2 adrenergic receptor agonist and a pharmaceutically acceptable carrier for the manufacture of a medicament for treating or preventing psoriasis or a symptom associated therewith in a subject, wherein the medicament is for topical administration to a skin area of the subject that is, or is prone to be, affected by psoriasis or the symptom associated therewith, and wherein the alpha-2 adrenergic receptor agonist is brimonidine; and wherein the medicament may further comprise titanium dioxide in an amount that is sufficient to mask the color of brimonidine or another coloured ingredient in the formulation, and may be in a form selected from the group consisting of sprays, mists, aerosols, solutions, lotions, gels, creams, ointments, pastes, unguents, emulsions, and suspensions.
Patent NZ-603052-A (NZ)
Title: Synergystic, non-equilibrium aldehyde biocides
Inventor: WHITELEY GREGORY STUART
IPC: A61L2/18
Filed: 2011-04-27
Abstract: A disinfectant solution comprising: an aldehyde; a polyol; one or more acetal derivatives formed by reaction of said aldehyde with said polyol; one or more surfactants selected from the general classes anionic, cationic, or non-ionic; one or more pH buffering agents selected from the group consisting of monosodium phosphate, disodium phosphate, trisodium phosphate, sodium tetraborate, sodium bicarbonate, sodium citrate, phosphoric acid, boric acid and citric acid. The disclosure also relates to a process of producing the disinfectant solution, and a method of disinfecting and/or sterilising heat sensitive medical devices comprising treating the medical devices with the disinfectant solution of the invention. The aldehyde may be o-phthalaldehyde.
Patent NZ-607633-A (NZ)
Title: Improved process for production of recombinant human growth hormone
Inventor: KANNER DOV
IPC: C12N1/38
Filed: 2011-09-20
Abstract: Disclosed is a process for the production of human growth hormone (hGH) comprising:, (i) fermenting human growth hormone producing E. coli cells;, (ii) recovering inclusion bodies from the E. coli cells and dissolving the recovered inclusion bodies at an alkaline pH to provide dissolved hGH;, (iii) optionally lyophilizing dissolved hGH;, characterized in that the fermentation is carried out in a culture medium comprising manganese, zinc, cobalt, molybdenum, calcium, copper, and boron as trace elements., Further disclosed is a method for reducing the amount of human growth hormone polymeric forms formed during a process for the production of human growth hormone (hGH) comprising the process as defined above.