baber/WOPTO huggingface dataset:
Patent CA-3093296-A1 (CA)
Inventor: LIPPERT JOHN A
IPC: A61M25/09
Filed: 2019-03-06
Abstract: The present disclosure relates to guidewire devices (900) having shapeable tips and effective torquability. A guidewire device includes a core (902) having a proximal section and a tapered distal section. A tube structure (904) is coupled to the core such that the tapered distal section extends into the tube structure. The tube structure includes a plurality of bypass cuts (930, 940) formed tangentially within the tube structure to increase the flexibility of the tube structure and to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.
Patent CA-3095055-A1 (CA)
Inventor: KUHNER-STOUT EMELINE
IPC: A41D13/00
Filed: 2019-03-28
Abstract: The present disclosure relates to energizing garments wearable by a user. The energizing garment is provided with compressive material and fingers (e.g., watershed fingers and/or massage (non-watershed) fingers) that can be positioned about the user's body to provide a combination of compression and penetrating massage to tissues that are oriented relative to watersheds of the user. The compressive material and fingers may be sized, shaped, oriented, or arranged in patterns to strategically energize the tissues of the user to release fluids, such as lymph, interstitial fluids, and/or blood, along or across the watersheds.
Patent CA-3097995-A1 (CA)
Title: Proteines de fusion de l'interleukine 12, et compositions et procedes therapeutiques associes
Inventor: FU YANG-XIN
IPC: C12N5/078
Filed: 2019-04-24
Abstract: L'invention concerne de nouvelles protéines de fusion de l'interleukine 12 et des promédicaments, et des compositions et des procédés de préparation de celles-ci, utiles dans le traitement de diverses maladies et troubles (par exemple l'hyperplasie, la tumeur solide ou la malignité hématopoïétique).
Patent CA-3099896-A1 (CA)
Inventor: PRIAMI CHRISTIAN
IPC: D03D15/58
Filed: 2019-05-17
Abstract: A protective fabric is described, preferably for motorcyclist professional clothing, said monolayer or coupled fabric comprising at least two coupled fabrics which surprisingly meets all the requirements of the applicable reference standards for abrasion, cut and burst resistance, while maintaining unchanged exceptional characteristics of softness, breathability, comfort, washability.
Patent CA-3102358-A1 (CA)
Inventor: MURAYAMA YUYA
IPC: F16H1/32
Filed: 2019-05-17
Abstract: A speed ratio switching type strain wave gearing (1) can switch the speed ratio of output rotation with respect to one input rotation into two states or multiple states with a simple configuration. The speed ration switching type strain wave gearing (1) includes first and second internally tooted gears (2, 3), an externally toothed gear (4) having first and second external teeth (45, 46) formed on the external peripheral surface thereof, a wave generator (5) that causes the first and second external teeth (45, 46) to partially mesh with the first and second internally toothed gears(2, 3), a clutch mechanism (6) that can selectively switch the first and second internally toothed gears (2, 3) into a fixed state. Input rotation from the wave generator (5) can be reduced in speed at a different speed ratio and derived from the externally toothed gear (4) by selectively switching the first and second internally toothed gears (2, 3) into a fixed state.
Patent CA-3104719-A1 (CA)
Title: Adaptive on-screen guide based on channel or content transition commands
Inventor: BREHM MICHAEL JAMES
IPC: H04N21/431
Filed: 2020-05-07
Abstract: Systems and methods for generating a content item sequence for display via an abbreviated on-screen guide are disclosed herein. Content selection commands are entered via a user interface of a computing device. Transition data, which describes content item playback transitions caused by the content selection commands, is stored in a buffer. Based on the transition data, a content family, which comprises a plurality of content items, is generated. A determination is made as to whether a content item currently being played back is included in the content family. In response to determining that the currently played-back content item is included in the content family, an on-screen guide, which comprises an abbreviated content item listing of the plurality of content items of the content family, is generated for display.
Patent CA-3106849-A1 (CA)
Title: Actionneur pourvu d'un ensemble amortisseur
Inventor: VAN OMMEN HERMAN
IPC: F15B15/22
Filed: 2019-07-25
Abstract: L'invention concerne un actionneur comprenant un boîtier, une tige d'actionneur et un ensemble amortisseur. L'actionneur comporte un axe, le boîtier comprend une première extrémité et une ouverture positionnée au niveau de la première extrémité du boîtier, et la tige d'actionneur s'étend à travers l'ouverture le long de l'axe de l'actionneur. L'ensemble amortisseur est monté au niveau de la première extrémité du boîtier, et comprend un ou plusieurs dispositifs d'absorption d'énergie. L'ensemble amortisseur est positionné sur le boîtier de sorte qu'un axe de chacun du ou des dispositifs d'absorption d'énergie soit décalé de l'axe de l'actionneur. L'ensemble amortisseur est conçu de sorte que le ou les dispositifs d'absorption d'énergie fournissent un amortissement de fin de course bidirectionnel.
Patent CA-3108171-A1 (CA)
Title: Power cable routing for a motor case
Inventor: KRUG BRIAN
IPC: B60K1/00
Filed: 2021-02-05
Abstract: A drive system (12) is disclosed. The drive system (12) may include a motor case (30), a generator (34) located externally at a first side of the motor case (30), an inverter (36) located externally at a second side of the motor case (30), and at least one tube (38) internal to the motor case (30). The at least one tube (38) may be configured to carry at least one power cable (40) that connects the generator (34) and the inverter (36).
Patent CA-3109413-A1 (CA)
Inventor: GUPTA VIVEK
IPC: H02S40/22
Filed: 2019-08-16
Abstract: L'invention concerne des systèmes et des procédés d'un ensemble collecteur d'énergie solaire et d'énergie thermique. Le système comprend un poteau central monté verticalement sur une base, une structure de support ayant des crémaillères concentriques s'étendant radialement à partir du poteau central, les crémaillères étant positionnées à différentes distances verticales le long du poteau central et ayant une configuration qui supporte les panneaux solaires, chaque crémaillère n'entravant pas le passage d'air et de lumière à travers la crémaillère, au moins un panneau solaire fixé à chaque crémaillère, chaque panneau solaire comprenant un réflecteur incurvé formé au niveau du bord radial du panneau solaire, une turbine à flux d'air disposée au sommet du poteau central, le poteau central ayant une ou plusieurs ouvertures et des conduits pour diriger de l'air chauffé vers la turbine à flux d'air ; et des conducteurs électriques pour fournir de l'électricité dérivée de cellules photovoltaïques dans chaque panneau solaire et à partir de la turbine de production d'électricité.
Patent CA-3111401-A1 (CA)
Inventor: MARIATHASAN SANJEEV
IPC: G01N33/574
Filed: 2019-09-17
Abstract: The present invention provides therapeutic and diagnostic methods and compositions for bladder cancer (e.g., a locally advanced or metastatic urothelial carcinoma). The invention provides methods of treating bladder cancer, methods of determining whether a patient suffering from bladder cancer is likely to respond to treatment comprising a PD-L1 axis binding antagonist, methods of predicting responsiveness of a patient suffering from bladder cancer to treatment comprising a PD-L1 axis binding antagonist, and methods of selecting a therapy for a patient suffering from bladder cancer, based on expression levels of a biomarker of the invention (e.g., PD-L1 expression levels in tumor-infiltrating immune cells in a tumor sample obtained from the patient).
Patent CA-3115103-A1 (CA)
Title: Inhibiteurs de pi3k et leurs utilisations
Inventor: FUSHIMI MAKOTO
IPC: C07D417/12
Filed: 2019-10-04
Abstract: L'invention porte sur le développement d'un nouveau paradigme d'administration de médicament ciblé couplé à des inhibiteurs de PI3K améliorés (par exemple, des inhibiteurs de PI3Ka), ledit développement représente une avancée considérable dans la thérapie contre le cancer. La présente invention concerne des composés de formule (I) et (II) et des sels, des hydrates, des solvates, des polymorphes, des cocristaux, des tautomères, des stéréo-isomères, des dérivés à marquage isotopique et des promédicaments pharmaceutiquement acceptables correspondants. Les composés de la présente invention sont des inhibiteurs de PI3K (par exemple, PI3Ka) et sont par conséquent utiles pour le traitement et/ou la prévention de diverses maladies (par exemple, de maladies prolifératives telles que le cancer). L'invention concerne également des nanoparticules et des nanogels (par exemple, des nanoparticules de ciblage de la P-sélectine) comprenant des inhibiteurs de PI3K, tel qu'un composé décrit dans la description. Selon certains modes de réalisation, une nanoparticule ou un nanogel de l'invention encapsule un composé de l'invention pour une administration ciblée à des cellules cancéreuses ou à des tumeurs.
Patent CA-3115302-A1 (CA)
Title: Multilateral multistage system and method
Inventor: CHO BRIAN WILLIAMS
IPC: E21B43/26
Filed: 2019-11-06
Abstract: Provided herein is an intervention tool and a method for fracturing multiple lateral wellbores in a well system. The intervention tool, in one aspect, includes a radial outer housing, the radial outer housing forming an interior bore configured to flow fluid, and an expansion member coupled proximate an outer surface of the radial outer housing. The intervention tool according to this aspect further includes a sliding sleeve positioned along an interior surface of the radial outer housing and engageable with the expansion member, the sleeve including a collection of slots or catches configured to move the expansion member between a radially retracted position when the sliding sleeve is in a first linear position and a radially expanded position when the sliding sleeve is in a second linear position.
Patent CA-3118538-A1 (CA)
Inventor: LATTA MARK A
IPC: A61K9/00
Filed: 2019-11-05
Abstract: An oral mucosal carrier comprising a combination of two different viscosity dimethicone components, wherein the difference between the two different viscosity dimethicone components is about 2.0 million cP or greater; and comprising at least one active agent.
Patent CA-3119716-A1 (CA)
Title: Azeotropically-modified blowing agents for forming foams
Inventor: MCADAMS CARINA
IPC: C08G18/42
Filed: 2019-11-07
Abstract: The present disclosure relates to improving insulation properties of foams by employing an azeotropically-modified blowing agent that preserves or improves R-value at various temperatures such as lower than ambient temperatures (below 24 ºC). The present disclosure also provides foams with improved long-term thermal resistance (LTTR).
Patent CA-3126618-A1 (CA)
Title: Ultrasonic gas meters and related flowtubes
Inventor: HEALY DAVID
IPC: G01F1/66
Filed: 2019-08-29
Abstract: An ultrasonic meter configured to operate in multiple classes is provided including a flowtube having an inlet at a first end and an outlet at a second end, opposite the first end; and first and second face to face transducers, the first transducer being positioned at the first end of the flowtube and the second transducer being positioned at the second end of the flowtube, wherein the first and second face to face transducers are positioned in line with flow through the ultrasonic meter. Related flowtubes are also provided herein.
Patent CA-3126802-A1 (CA)
Title: Methods of treating pain with a thiazoline anti-hyperalgesic
Inventor: DAX SCOTT
IPC: A61P25/02
Filed: 2019-12-19
Abstract: Methods of treating diabetic neuropathic pain and post-surgical pain are provided. The methods include administering to an individual a therapeutically effective amount of a compound of Formula I (Compound 1). The method can be used to treat diabetic neuropathy arising from any type of nerve damage, and can also be used to treat post-surgical pain arising from any surgical procedure without the side effects associated with widely used analgesics such as opioids. Compound 1 can be formulated into many suitable dosage forms, including oral dosage forms such as tablets.
Patent CA-3129252-A1 (CA)
Inventor: PFEIFER ANDREA
IPC: A61P25/28
Filed: 2020-02-07
Abstract: Methods for inducing anti-phosphorylated Tau antibodies without inducing a severe adverse event in humans are described. The methods include administering to the subject an effective amount of liposomes including a toll-like receptor 4 agonist and a Tau phosphopeptide presented on the surface of the liposome.
Patent CA-3130068-A1 (CA)
Title: Completely laparoscopic staged hepatectomy using round-the-liver ligation and its instrument
Inventor: CAI XIUJUN
IPC: A61B17/00
Filed: 2021-09-07
Abstract: The present invention discloses a completely laparoscopic staged hepatectomy using round-the-liver ligation, which is carried out as follows: (1) a complete laparoscopic operation is performed with general anesthesia using round-the-liver ligation, the branches of the portal vein of the hemiliver to be removed are ligated, meanwhile a tourniquet is used to tighten the connecting part between the right and the left hemilivers to block the communicating blood flow between the hemiliver to be removed and the hemiliver to be reserved, a drainage tube is put into the peritoneal cavity at the hepatic hilus, then close the peritoneal cavity, and the operation is completed; (2) the patient gradually resumes eating after the first operation, and recuperate for 6-15 days to make the volume of the hemiliver to be reserved increase to the expected volume of the future liver remnant, in which the expected volume of the future liver remnant should be at least 30-40% of the standard liver volume; (3) after the volume of the hemiliver to be reserved has increased to the expected volume of the future liver remnant, a complete laparoscopic liver resection is carried out with general anesthesia to remove the diseased hemiliver, and then the patient is nursed to be completely recovered. The invention also discloses a instmment for implementing the completely laparoscopic staged hepatectomy using round-the-liver ligation.
Patent CA-3131206-A1 (CA)
Inventor: Holcombe Michael Sean
IPC: H04W40/08
Filed: 2020-02-21
Abstract: A system for selecting a communication mode for a transmitting node to communicate with a receiving node in a mesh network is provided. For example, a transmitting node can gather mode selection data that describe communication conditions of the transmitting node and the receiving node. Based on the mode selection data, the transmitting node can determine a first white list of modes that can be used by the transmitting node to successfully transmit data packets to the receiving node. The transmitting node also determines a second white list of modes that can be used by the receiving node to send acknowledgment packets successfully to the transmitting node. The transmitting node further identifies overlapped modes between the first and second white lists of modes. The transmitting node can then select one of the overlapped modes for transmitting data packets to the receiving node.
Patent CA-3131268-A1 (CA)
Inventor: RAO SUDHA
IPC: G01N33/53
Filed: 2020-02-27
Abstract: This disclosure relates generally to methods and agents for assessing T-cell function and for predicting responses to therapy. More particularly, the present invention relates to methods and agents for detecting different forms of Eomesodermin (EOMES) in T-cells, which are useful for assessing the function of a T-cell, for assessing the immune function of a subject, for predicting the likelihood of response of a cancer patient to therapy including immunotherapy, for stratifying a cancer patient as a likely responder or non-responder to a therapy, and for managing treatment of a cancer patient.
Patent CA-3131684-A1 (CA)
Title: Computer systems and methods for enhancing neurorehabilitation
Inventor: SKINNER KIMBERLY LYNN
IPC: A61N1/372
Filed: 2020-02-26
Abstract: A computerized method of processing data including receiving, from a portable neurostimulation device having a controller, portable neurostimulation device identifying information; receiving, from a healthcare professional, patient identifying information for a patient; creating an electronic record for the patient, the electronic record pairing the portable neurostimulation device identifying information with the patient identifying information; receiving, via a healthcare professional, first input specifying a first treatment regimen for the patient; processing the first input specifying the first treatment regimen, thereby creating a device-ready first treatment regimen; sending, to the portable neurostimulation device, the device-ready first treatment regimen; receiving, from the portable neurostimulation device, first treatment regimen data for the patient; and generating, based on the first treatment regimen data, a first treatment regimen data set for the patient.
Patent CA-3132985-A1 (CA)
Inventor: NISTALA HARIKIRAN
IPC: C07K14/47
Filed: 2020-03-12
Abstract: The present disclosure provides methods of treating subjects having increased serum glucose level and/or hyperglycemia, methods of identifying subjects having an increased risk of developing increased serum glucose level and/or hyperglycemia, and methods of detecting human Solute Carrier Family 39 Member 5 variant nucleic acid molecules and variant polypeptides.
Patent CA-3133732-A1 (CA)
Title: Use of compounds in the preparation of a medicament for treating atherosclerosis
Inventor: FU XIN-YUAN
IPC: A61K31/454
Filed: 2020-04-24
Abstract: Disclosed is the use of a compound in the preparation of a drug for treating atherosclerosis, wherein the compound comprises one or more of a compound of formula I, Nib2 and a pharmaceutically acceptable salt thereof. Based on the pathogenic mechanism of atherosclerosis and the generation of an inflammatory response, previous studies have shown that the compound may significantly inhibit the foaming of macrophages, reduce the deposition of fatty necrotic substances, reduce plaque formation, and may delay or inhibit atherosclerosis to some extent.
Patent CA-3136516-A1 (CA)
Inventor: KINEW WABANAKWUT
IPC: H04W4/02
Filed: 2021-10-28
Abstract: The present disclosure relates to a novel augmented reality system which implements a social network on mobile digital computing devices with single-layer transparent displays which can delineate opaque and transparent regions of any shape, and where the single-layer transparent display shows graphics on-screen relative to the user's line of sight. The user's local device runs client software which allows it to access and interact with the server software which powers the augmented reality social network and runs other back-end functionality such as allowing the user to access the internet.
Patent CA-3136557-A1 (CA)
Inventor: DU XIULIANG
IPC: B32B27/32
Filed: 2021-08-18
Abstract: The present disclosure provides a BOPP double-sided heat-sealing laser anti-counterfeiting base film, comprising an upper layer structure, a middle layer structure and a lower layer structure arranged in sequence. Compared with the prior art, the present disclosure uses the upper layer structure to provide good heat-sealing performance, good slip performance and anti-blocking performance between the films; adds petroleum resin and antistatic agent to the middle layer structure to make the film have a high shrinkage rate and modulus and good antistatic effect, and adds low-temperature heat-sealing metallocene and propylene-ethylene-butadiene terpolymer to the lower layer structure to make the blended modified film have a low sealing temperature and good compression molding effect, so that the obtained BOPP double-sided heat-sealing laser anti-counterfeiting base film has the advantages of good heat sealing, good heat resistance of the pattern after compression molding, and low raw material costs.
Patent CA-3137587-A1 (CA)
Title: Compositions and methods for modulation of antibody activity
Inventor: KARANICOLAS JOHN
IPC: A61P35/00
Filed: 2020-04-29
Abstract: Compositions and methods for modulating antibody activity are disclosed.
Patent CA-3138208-A1 (CA)
Title: Method for planning tissue ablation based on deep learning
Inventor: OUBEL ESTANISLAO
IPC: G06N3/08
Filed: 2020-06-25
Abstract: The invention relates to a method (100) and device for planning a surgical procedure aiming to ablate a tissue (32) in an anatomical area of interest (31) of a patient (30). On the basis of a preoperative image (50) of the anatomical area of interest and of a set of planning parameters (P), a simulated image (51) is generated by a neural network that has been previously trained using learning elements corresponding, respectively, to a similar surgical procedure for ablating a tissue in an anatomical area of interest for another patient. Each learning element comprises a preoperative image (50) of the anatomical area of interest of a patient, planning parameters (P) used for the surgical procedure on this patient, and a postoperative image (52) of the anatomical area of interest of this patient after the surgical procedure. An estimated ablation region (34) may be segmented in the simulated image (51) in order to be compared with a segmented region to be treated (33) in the preoperative image (50).
Patent CA-3140338-A1 (CA)
Inventor: PRESBY DAVID W
IPC: C10L5/44
Filed: 2021-11-24
Abstract: A biofuel pellet and an apparatus for making the pellet are provided. The biofuel pellet includes a first region of high density and a second region of low density. The higher density region burns more slowly than the low density region and helps to suspend the pellet for longer and more complete combustion.
Patent CA-3142753-A1 (CA)
Title: Power consumption management through energy storage devices
Inventor: STEFFES PAUL J
IPC: H02J15/00
Filed: 2015-01-16
Abstract: An energy storage device (104) includes a device controller (106), an electrical energy converter (108), an energy storage medium (110) and a power metering device (170). In a method of managing electrical power consumption by a group of the energy storage devices, a measured power level (172) is output (174) from the power metering device of each energy storage device.  The power level represents a rate of electrical energy consumption by the electrical energy converter of the device. The measured power levels of each of the devices are communicated (176) to a system controller (102) using the device controllers. An aggregate power level (184) is calculated (178) based on the measured power levels, and is stored (180) in memory (124) using the system controller. In some embodiments, the aggregate power level is communicated (190) to a remote location, such as an electrical power distribution system (112).