baber/WOPTO huggingface dataset:
Patent FI-852925-A0 (FI)
Inventor: OSTERMAN MICHEL ERNEST
IPC: C08L97/02
Filed: 1985-07-26
Abstract: The invention relates to the production of decorative panels. The process for production according to the invention is characterized in that: an epoxy resin which is liquid and polymerizing at ambient temperature in the presence of a polymerization reagent having the least reactive character at the same temperature, fragments and/or pieces of wood previously heated to a homogeneous temperature higher than the peak temperature of exothermia of polymerization of the resin-reagent mixture, are used. The invention is more particularly applicable to the manufacture of decorative trays for tables.
Patent FI-884135-A0 (FI)
Inventor: KARDOS PETER
IPC: C09K5/08
Filed: 1988-09-08
Abstract: The invention relates to a partly or fully glycol-free multi-component frost resistant cooling fluid comprising 3 to 6 parts by weight of water, 0.5 to 1.5 parts by weight of urea, at most 1.5 parts by weight of glycol, 1 to 2 parts by weight of sodium formate, and 1 to 2 parts by weight of sodium acetate as main components. The invention further relates to a glycol-free multi-component frost resistant cooling fluid comprising 4 to 7 parts by weight of potassium acetate, at most 1.5 parts by weight of potassium formate and 3 to 9 parts by weight of water as main components. Fluids according to the invention can be optionally mixed with the well-known glycol-based cooling fluids.
Patent FI-895482-A0 (FI)
Inventor: SEQUEIRA JOEL A
IPC: A61K31/57
Filed: 1989-11-17
Abstract: An improved lotion formulation for the topical administration of corticosteroids in a hydro-alcoholic base containing propylene glycol.
Patent FI-900146-A0 (FI)
Inventor: CLIFF GEOFFREY ROSS
IPC: A01N43/76
Filed: 1990-01-11
Abstract: Compounds of formula I <CHEM> wherein X is oxygen or sulphur, W is CH or N, m is 0 or 1, and either a) n is 1 and Q is a non-aromatic heterocyclic ring of 3 to 10 ring atoms, containing one to three hetero atoms selected from oxygen, sulphur and nitrogen, which may be substituted and may be fused to another ring, with the proviso a) that if Q is thiazol-2-in-2-yl, it is substituted but not by methylene, and b) Q is not a six membered ring containing only two nitrogen atoms, or b) n is 0 or 1 and  Q is <CHEM> where R<1> is alkyl, alkoxy or alkylthio, and R<2> is heteroaryl, non aromatic heterocyclyl, optionally substituted cycloalkyl or optionally substituted alkyl containing at least 5 carbon atoms, phenyl substituted by one or more groups selected from halogen, optionally substituted alkyl, alkoxy, haloalkoxy, aryloxy, alkylthio and alkoxycarbonyl, and when R<1> is alkyl or alkoxy, or, when W is nitrogen, R<2> can also be unsubstituted phenyl, have pesticidal especially fungicidal activity.
Patent FI-934728-A0 (FI)
Inventor: SMITH GEORGE A
IPC: C08G69/48
Filed: 1993-10-26
Abstract: Stable, one-component, curable epoxy resin and polyamide resin dispersions and methods for the preparation of the same are described, wherein the polyamide resin dispersion has a stability enhancing, water soluble, dipolar chemical moiety.
Patent FI-943462-A0 (FI)
Inventor: SUNDREHAGEN ERLING
IPC: C07H19/16
Filed: 1994-07-21
Abstract: There is provided a method for assaying homocysteine in a sample, e.g. blood, plasma or urine, which comprises the steps of contacting said sample with a homocysteine converting enzyme other than SAH-hydrolase and at least one substrate for said enzyme other than homocysteine, and without chromatographic separation assessing a non-labelled analyte selected from a homocysteine co-substrate and the homocysteine conversion products of the enzymic conversion of homocysteine by said enzyme.
Patent FI-944952-A0 (FI)
Inventor: PASSCHIER BOB
IPC: A22C17/02
Filed: 1994-10-21
Abstract: PCT No. PCT/NL93/00087 Sec. 371 Date Dec. 19, 1994 Sec. 102(e) Date Dec. 19, 1994 PCT Filed Apr. 22, 1993 PCT Pub. No. WO93/20703 PCT Pub. Date Oct. 28, 1993.A device for detaching and/or removing meat and the like from animal heads (2), comprises a conveyor line (4) with a series of holders (3) for heads, placed one after the other, spaced apart, in the direction of conveyance, on which holders essentially identically shaped animal heads (2) with essentially the same dimensions can be placed. Processing stations are disposed along the conveyor line at a distance from each other, past which stations the animal heads are moved and treated in succession by the conveyor line. Mechanically driven separators (14, 21; 36, 27, 28; 51; 54; 66, 72, 74, 75) comprise pin-shaped members (21, 36, 27, 51, 66) movable toward and away from said conveyor line (4) and fixed in such a way that they are resiliently movable. The device has a station (70) with a device for separating the lower jaw (22) from the animal head, which act on the free end (76) of the lower jaw for moving the free end a distance from the animal head.
Patent FI-954374-A0 (FI)
Inventor: HYPPAENEN TIMO
IPC: B01J8/38
Filed: 1995-09-18
Abstract: In a fluidized bed reactor particles are internally circulated, moving down the walls forming the reactor chamber. A particle chamber having a particle gathering top wall with a horizontal projection area A is disposed in the downward flow of particles. Openings (e.g. holes or slots) with a controlling dimension of about 30 mm or less are provided in the top wall, the openings having total open area B less than half the area A. Heat transfer surfaces may be disposed in the particle chamber.
Patent FI-954723-A0 (FI)
Inventor: SCHULTE HEINZ-GUENTHER
IPC: D21H21/02
Filed: 1995-10-04
Abstract: The invention relates to a process for controlling the deposition of stickies from paper stock suspensions in papermaking. According to the invention, the deposition of stickies is controlled by addition of an effective quantity of a degradation product of native starch to the paper stock suspension.
Patent FI-961089-A0 (FI)
Inventor: IJKELEMSTAM EVERT PIETER
IPC: H04M1/57
Filed: 1996-03-08
Abstract: System for detecting the identifier of a component of a telecommunication system such as a terminal component, transmission component or switching component. The system comprises a detector (2) which is connected to the component (3), furthermore a remitter (4) which is connected to a second component (5). The detector dials the second component, and the telecommunication system transmits the identifier of the first component to the remitter ("calling number display" service). The remitter sends the identifier of the first component back to the detector, where the requested identifier can be read out on a display. To summarize, relatively large savings are obtained by only one operator instead of two necessary for testing; time gained in the event of malfunctions; direct and undistorted data exchange; recording of the data on a printer possible; fits into a system for guaranteeing quality; increases the performance of the telecommunication system; avoids unnecessary investment in cable/bundle/channel capacity.
Patent FI-962440-A0 (FI)
Inventor: HESSE ROBERT HENRY
IPC: A61P17/00
Filed: 1996-06-12
Abstract: PCT No. PCT/GB94/02725 Sec. 371 Date Jul. 31, 1996 Sec. 102(e) Date Jul. 31, 1996 PCT Filed Dec. 13, 1994 PCT Pub. No. WO95/16672 PCT Pub. Date Jun. 22, 1995The invention relates to vitamin D amine and amide derivatives of general formula    <IMAGE>  (I)  where R represents a hydrogen atom, an aliphatic, cycloaliphatic or araliphatic group, or an acyl group comprising an aliphatic, cycloaliphatic, arylaliphatic or aryl group linked to the nitrogen atom by way of a carbonyl group; R1 and R2 are each selected from lower alkyl and cycloalkyl groups or together with the carbon atom to which they are attached form a lower cycloalkyl group; R3 represents a methyl group having  alpha - or  beta -configuration; Y represents a lower alkylene, alkenylene or alkynylene group optionally substituted by a hydroxyl, etherified hydroxyl or esterified hydroxyl group; and A= represents a cyclohexylidene moiety characteristic of the A-ring of a 1  alpha -hydroxylated vitamin D or analogue thereof. Active compounds of the invention exhibit cell modulating activity and in certain cases may also have an effect on calcium metabolism. The compounds of the invention may be prepared by isomerizing a 5,6-trans isomer of formula (I) to a corresponding 5,6-cis isomer; by hydroxylating a 1-unsubstituted-5,6-trans analogue of a compound of formula (I) to prepare a 5,6-trans isomer of formula (I); by reacting a compound containing a precursor for the desired 17-position side chain in one or more stages and with one or more reactants serving to form the desired side chain; or by reacting a compound of formula (I) to modify the substitution pattern about the A= group.
Patent IL-66286-A0 (IL)
Title: (3s-(3 alpha(z),4 beta))-3-(((2-amino-4-thiazolyl)(1-carboxy-1-methylethoxy)imino)acetyl)amino)-4-methyl-2-oxo-1-azetidinesulfonic acid and method for preparation thereof
IPC: A61K9/14
Filed: 1982-07-09
Abstract: The crystalline anhydrous form of [3S-[3 alpha (Z),4 beta ]]-3-[[2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]ami no]-4-methyl-2-oxo-1-azetidinesu lfonic acid is prepared.
Patent IL-79166-A0 (IL)
Title: Heteropolysaccharide s-184 and its production
IPC: C12R1/05
Filed: 1986-06-19
Abstract: Heteropolysaccharide S-184 is a new heteropolysaccharide. It is composed principally of carbohydrate, from 12% to 16% protein and from 3.0% to 4.5% (calculated as acetic acid) acyl groups, the carbohydrate portion containing from about 7% to 16% uronic acid and the neutral sugars mannose, glucose and galactose in the approximate molar ratios of 1:3:5. It can be prepared by fermentation of a new Alcaligenes species, ATCC 53160. It has valuable properties as a thickening, suspending and stabilizing agent in aqueous solutions and is especially valuable for use in foods.
Patent IL-80962-A0 (IL)
Title: Thiadiazole antiviral agents
IPC: A61K31/44
Filed: 1986-12-15
Abstract: (1) 1,3,4-Thiadiazole-2-cyanamide and derivs. of formula (I) and their salts are new. In (I), R1 = H; R2 = CN; or R1+R2 = =C(SR6)NH2 or =C(NH2)2; R6 = 1-4C alkyl, cyano-(1-4C)alkyl or pyridyl-(1-4C)alkyl. (2) In vitro antiviral method for protecting mammalian cells in culture comprises adding to the culture a cpd. (I) in which either (A) R1 = H; R2 = CN or =CH-NHR3; or R1+R2 = =C(NH2)2 or =CR5-NHR3(1); R3 = COOR4; R3(1) = H or COOR4; R4 = 1-10C alkyl, 2-10C alkenyl or Ph, each opt. substd.; R5 = H or SR6; R6 = 1-4C alkyl, cyano-(1-4C)alkyl or pyridyl-(1-4C)alkyl; or (B) as defined for (A) except that R1+R2 = =CR5NHR31 only; and R3, R31 = H or COOR4.
Patent IL-84269-A0 (IL)
Title: Transdermal flux enhancing compositions
IPC: A61K47/00
Filed: 1987-10-25
Abstract: A transdermal flux enhancing pharmaceutical composition for transdermal administration to a human or lower animal subject comprising a safe and effective amount of a pharmacologically active compound or a prodrug thereof, an aqueous ethanol solvent containing from 15 to 75% ethanol by volume, and a penetration enhancer selected from certain 1-alkylazacycloheptan-2-ones and cis-olefin compounds of the formula  CH3(CH2)xCH=CH(CH2)yR<3> where R<3> is CH2OH, CH2NH2 or COR<4> and R<4> is OH or (C1-C4)alkoxy, x and y are each an integer from 3 to 13 and the sum of x and y is from 10 to 16; methods for their use in treating various illnesses in a human or lower animal by transdermal administration of said composition.
Patent IL-98454-A0 (IL)
Title: Derivatives of 2-aminoalkyl-5-arylalkyl-1,3-dioxanes,their preparation and their therapeutic application
IPC: A61K31/357
Filed: 1991-06-11
Abstract: A compound which is a 2-aminoalkyl-5-arylalkyl-1,3-dioxane of general formula (I)   <IMAGE> (I)  in which m represents 0 or 1; n represents 1, 2, 3 or 4; R1 represents hydrogen or methyl; R2 represents hydrogen, methyl or an alkanoyl group of the general formula COR' in which R' represents a hydrogen atom or a linear or branched C1-C4-alkyl group, or an alkoxycarbonyl group of the general formula COOR'' in which R'' represents a linear or branched C1-C4-alkyl group; and Ar represents either a phenyl group optionally carrying one or two substituents selected from halogen, C1-C4 alkyl, methoxy and trifluoromethyl, or a naphthalen-1-yl or naphthalen-2-yl group optionally carrying a substituent selected from halogen, methyl, methoxy and cyclopropylmethoxy groups, in the form of a cis- or trans-stereoisomer, and in the form of a free base or an acid addition salt thereof and its therapeutic use.
Patent IL-99355-A0 (IL)
Title: Acid stabilized food products
IPC: A23L3/3508
Filed: 1991-08-30
Abstract: An acid-stabilized foodstuff is prepared with at least one polymeric food-acceptable acid.
Patent AU-PO656397-A0 (AU)
Title: Improvements relating to method and apparatus for producing stretch wrap plastic film
IPC: A01F25/13
Filed: 1997-05-01
Abstract: The present specification discloses a plastics material film (1) that is stretched beyond its yield point to about 100% to 400% elongation and thereafter only partially relaxed to release part of the elastic deformation component in the film to retain between about 20% and 80% of the elastic deformation in the film (1), the film thereafter being stored in this partially relaxed state whereby, when it is used, the retained elastic deformation capability is useable for the intended purpose of the film, for example, wrapping a load.
Patent FI-20002598-A0 (FI)
Inventor: HALTTUNEN LASSE ARTTURI
IPC: H04M1/72412
Filed: 2000-11-27
Abstract: The invention relates to a method for transmitting image and sound from a mobile phone to an ordinary analog television receiver using a mobile phone accessory. The invention relates to third generation UMTS-/IMT 2000 data terminal equipments, all kinds of GSM-applications, such as: WAP, HSCSD, GPRS, EDGE and CDMA-phones. The invention is based on that the accessory module ( 2 ) is attached to an ordinary analog television receiver ( 3 ). Bluetooth technology is exploited in data transmission from the mobile phone to the accessory attachable to the television. Because of its function, smallness and essence the accessory module is suitable as mobile phone accessory. The accessory module uses supply current. The module operating as an accessory comprises in addition to the actual modification part, also a Bluetooth accessory, which receives image and sound transmitted by the modile phone, e.g. UMTS data terminal equipment. The modification part converts signals conformable to each equipment type to RGB-controlling signals and sound. The Bluetooth receiver in the module is attached to the converter by using an interface conformable to USB-standard. The Bluetooth accessory is attached to the mobile phone, this accessory can forward image and sound received by the mobile phone to the television receiver module nearby in the air interface in the free 24 Ghz frequency band.
Patent FI-20106088-A0 (FI)
Inventor: HOVINEN ANSSI
IPC: B05B12/18
Filed: 2010-10-21
Abstract: A surface treatment device that ejects a combination of precursor substances as a directed flow of surface treatment particles. Planar objects are conveyed along a defined plane through the particle flow, a region on the surface of the planar object that the particle flow hits forming a region of direct impact. The device comprises directing means for directing the particle flow to travel along the surface of the planar object in an extended impact region outside the region of direct impact; and flow control means for controlling the extent of the extended impact region which may include a vortex flow. The exposure of the treated surface with the particle flow increases and the probability of the desired surface treatment processes to take place increases.
Patent IL-100698-A0 (IL)
Title: Polyamine thiols as radioprotective agents
IPC: C07C323/32
Filed: 1992-01-19
Abstract: The present invention relates to compounds of formula (1) or (2) which are useful as radioprotective agents. <CHEM>  wherein  n is an integer from 0 to 3,  m is an integer from 4 to 9,  Z is a C2-C6 alkylene group, A is H, -SH, -SPO3H2, -N(CH2)q-SH, -N(CH2)q-SPO3H2, wherein q is an integer 2 to 4, and  B1 and B2 are each independently H, -(CH2)q-SH, or -(CH2)q-SPO3H2, <CHEM>  wherein  n is an integer from 0 to 3,  Z is a C2-C6 alkylene group, A is H, -SH, -SPO3H2, -N(CH2)q-SH, -N(CH2)q-SPO3H2, wherein q is an integer 2 to 4, and  B1 and B2 are each independently H, -(CH2)q-SH, or -(CH2)q-SPO3H2, with the proviso that at least one of A, B1 and B2 is other than H.
Patent IL-101162-A0 (IL)
Title: Pharmaceutical compositions for oral administration comprising an indole derivative
IPC: A61K47/38
Filed: 1992-03-06
Abstract: A pharmaceutical composition for oral adminstration comprising a film-coated solid dosage form including 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulphonamide or a pharmaceutically acceptable salt or solvate thereof as active ingredient. The film-coated solid dosage forms are of use in the treatment of conditions associated with cephalic pain, in particular migraine.
Patent IL-104139-A0 (IL)
Title: Recombinant dna compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus
IPC: C12R1/125
Filed: 1992-12-17
Abstract: The present invention provides isolated DNA compounds and recombinant DNA cloning and expression vectors that encode PNB esterase from Bacillus subtilis. The invention also provides host cells transformed with these vectors and a method for production of the PNB esterase by recombinant DNA techniques.
Patent IL-111185-A0 (IL)
Title: Quinolizinone type compounds
IPC: C07D213/61
Filed: 1994-10-06
Abstract: Antibacterical coumpounds having formula (I) and the pharmaceutically acceptable salts, esters and amides thereof, preferred examples of which include those coumpounds wherein R<1> is cycloalkyl of from three to eight carbon atoms or substituted phenyl; R<2>is selected from the group consisting of (a) halogen, (b) loweralkyl, (c) loweralkenyl, (d) cycloalkyl of from three to eight carbons, (e) cycloalkenyl of from four to eight carbons, (f) loweralkoxy, (g) aryloxy, (h) aryl(loweralkyl)oxy, (i) aryl(loweralkyl), (j) cycloalkyl(loweralkyl), (k) amino, (l) (loweralkyl)amino, (m) aryl(loweralkyl)amino, (n) hydroxy substituted (loweralkyl)amino, (o) phenyl, (p) substituted phenyl, (q) bicyclic nitrogen-containing heterocycle, (r) nitrogen-containingaromatic heterocycle, and (s) nitrogen-containing heterocycle having formula (Ia) where x is between zero and three; R<3> is halogen; R<4> is hydrogen, loweralkyl, a pharmaceutically acceptable cation, or a prodrug ester group; R<5> is hydrogen, loweralkyl, halo(loweralkyl), or -NR<13>R<14>; and R<6> is loweralkyl, as wellas pharmaceutical compositions containing such compounds and the use of the same in the treatment of bacterial infections.
Patent IL-112413-A0 (IL)
Title: Watersoluble azoles, their preparation and pharmaceutical compositions containing them
IPC: A61K31/34
Filed: 1995-01-23
Abstract: PCT No. PCT/EP95/00174 Sec. 371 Date Jun. 20, 1996 Sec. 102(e) Date Jun. 20, 1996 PCT Filed Jan. 17, 1995 PCT Pub. No. WO95/19983 PCT Pub. Date Jul. 27, 1995A compound of formula (I),    <IMAGE>  (I)  or a stereochemically isomeric form thereof, wherein A and B taken together form -N=CH-, -CH=N-, -CH2-CH2, CH=CH-, -C(=O)-CH2-, -CH2-C(=O); D is a radical of formula    <IMAGE>  (D1)   <IMAGE>  (D2) GE>  (L1)   <IMAGE>  (L2)  Alk is a C1-4alkanediyl radical; R1 is halo; R2 is hydrogen or halo; R3 is hydrogen, C1-6alkyl, phenyl or halophenyl; R4 is hydrogen, C1-6alkyl, phenyl or halophenyl; R5 is hydrogen or C1-6alkyl; R6 is hydrogen, C1-6alkyl, C1-6alkyloxycarbonyl, or R5 and R6 taken together with the nitrogen atom to which they are attached form a heterocyclic ring. Active intermediates, compositions and methods of preparing compounds, compositions are described.
Patent IL-115708-A0 (IL)
Title: Calcification-resistant bioprosthetic tissue and methods of making same
IPC: A61L27/36
Filed: 1995-10-20
Abstract: Naturally-derived bioprosthetic materials are treated with epoxide crosslinking agents. In some embodiments, the tissue is crosslinked with low molecular weight epoxides in aqueous solutions at high pH levels. In other embodiments, the tissue is crosslinked at physiologic pH levels with epoxide crosslinking agents catalyzed with tertiary or quaternary amines, such as Tris or imidazole. In an advantageous embodiment, bioprosthetic tissue is crosslinked and derivatized with an anticalcification agent, such as a polyphosphonate anticalcification agent, using a polyphosphonate:polyepoxide monoadduct.
Patent IL-117474-A0 (IL)
Title: Ultrasonic atomizer device with removable precision dosating unit
IPC: A61M11/00
Filed: 1996-03-14
Abstract: PCT No. PCT/EP96/01092 Sec. 371 Date Sep. 10, 1997 Sec. 102(e) Date Sep. 10, 1997 PCT Filed Mar. 14, 1996 PCT Pub. No. WO96/28205 PCT Pub. Date Sep. 19, 1996The invention relates to an ultrasonic atomizer device (2) for a fluid (60), in particular a bronchospasmolytic agent, in which a propelling element (10) operable by an electronic circuit (6) to deliver the fluid to an atomization surface (28) that is also supplied with ultrasound waves from the electronic circuit (6) is provided in a housing (4), the propelling element (10) having a coupling member (32) which is meshing with a further coupling member (34) of a replaceable dosating unit (14) for transferring propelling power to the dosating unit (14) to effect a linear movement (68) of a piston (66) arranged in an ampoule (28) within the dosating unit (14). The invention also relates to a system comprising a device (2) as described and a dosating unit (14) inserted into that device (2).
Patent IL-118727-A0 (IL)
Title: Preparation of bicyclohexane derivative
IPC: C07C62/24
Filed: 1996-06-24
Abstract: A process for the preparation of (+)-2-amino-bicycloÄ3.1.0Ü-hexane-2-6-dicarboxylic acid, or a pharmaceutically acceptable salt thereof, which comprises hydrolysing (-)-2-spiro-5'-hydantoinbicycloÄ3.1.0Ühexane-6-carboxylic acid or a salt thereof, and optionally forming a pharmaceutically acceptable salt. Also disclosed are novel intermediates useful in the process.
Patent IL-120082-A0 (IL)
Title: Method for determining the amount of an amylin receptor binding compound in a sample
IPC: C07K14/585
Filed: 1997-01-27
Abstract: Methods for identifying or screening or characterizing or assaying or isolating known or candidate agonists and antagonists of amylin, comprising binding assays utilizing preparations containing specific receptors for amylin. Membranes from the brain that contain high density receptors for amylin are particularly useful for the methods of this invention, and as a source of amylin receptors.
Patent IL-121749-A0 (IL)
Title: 2,3-dioxabicycloÚ3.3.1¾nonane derivatives and antimalarial pharmaceutical compositions comprising them
IPC: C07D319/02
Filed: 1997-09-11
Abstract: PCT No. PCT/IL98/00440 Sec. 371 Date May 11, 2000 Sec. 102(e) Date May 11, 2000 PCT Filed Sep. 10, 1998 PCT Pub. No. WO99/12900 PCT Pub. Date Mar. 18, 19992,3-Dioxabicyclo[3.3.1]nonane derivatives, carrying, at position 4, a sulfur-containing functionality selected from the group consisting of sulfonyl, sulfinyl and sulfenyl, adhered to C(4) vie methylene group, represented by structural formula (A) wherein: X is hydrogen, hydroxy, alkoxy, optionally substituted by alkoxy or acyloxy, aralkoxy optionally substituted by alkoxy or aryloxy, and M is hydrogen, hydroxy, alkoxy, alkenyloxy, acyloxy, optionally substituted by acyl or acyloxy, aralokoxy, arylalkenyloxy, oxalyloxy substituted by alkoxy, di(alkyl)amino or alkyl(aryl)amino, di(aralalkyl)amino or carbonyloxy substituted by arloxy, di(alkyl)amino, di(aralkyl)amino and alkyl(aryl)amino; or X and M together represent a carbon-carbon bond or an oxygen atom; L is hydrogen or L and M together represent a carbon-carbon bond; and either Z is a radical R-S(=O)n- and Y is hydrogen, or Y is R-S(=O)n- and Z is hydrogen, wherein R is alkyl optionally substituted by alkoxy or alkoxycarbonyl, cycloalkyl, or aryl or araklkyl optionally substituted by alkyl, halogen or CF3; and n is 0, 1, or 2, are useful for the prevention and/or treatment of malaria.