baber/WOPTO huggingface dataset:
Patent DK-1828178-T3 (DK)
Inventor: MEZEI TIBOR
IPC: A61K31/427
Filed: 2005-12-16
Granted: 2011-02-14
Abstract: The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam.
Patent DK-1920497-T3 (DK)
Inventor: MARROCCO GAETANO
IPC: H01Q5/00
Filed: 2006-05-18
Granted: 2009-04-27
Abstract: A linear antenna for operation in the HF frequency range, particularly for naval communications is disclosed, comprising a radiating arrangement (H1, H2, H3, W1, W2), adapted to be operatively associated with a ground conductor (20) and at least one electrical impedance device (Z1-Z4), characterized in that it includes: a plurality of wire radiating elements with a predominantly vertical extension, forming a first and a second conducting branch (H1, H2) adapted to be operatively coupled to a feed circuit, and a return conducting branch (H3) adapted to be operatively coupled to a ground conductor (20); and a plurality of wire radiating elements with a predominantly transverse extension, forming connecting conducting branches (W1, W2) for connecting the conducting branches (H1, H2) adapted to be coupled to the feed circuit (12), to the conducting branch (H3) adapted to be coupled to the ground conductor (20), the radiating elements being positioned in such a way as to form, in a plane in which the antenna lies, two nested closed paths (P1, P2) between the feed circuit (12) and the ground conductor (20), having at least one radiating element in common, and—a plurality of electrical impedance devices (Z1-Z4) interposed along the conducting branches (H1, H2, H3, W1, W2) and adapted to impede the flow of current within corresponding predetermined frequency ranges in such a way as to establish selectively, according to the operating frequency, a plurality of different current paths along the conducting branches (H1, H2, H3, W1, W2), corresponding to a plurality of different electrical and/or geometrical configurations of the antenna (10).
Patent DK-1926996-T3 (DK)
Inventor: HALEY JOHN D
IPC: G01N33/574
Filed: 2006-09-19
Granted: 2012-01-23
Abstract: The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor. Methods are provided for predicting the sensitivity of tumor cell growth to inhibition by an IGF-IR kinase inhibitor, comprising assessing whether the tumor cell has undergone an epithelial to mesenchymal transition (EMT), by determining the expression level of epithelial and/or mesenchymal biomarkers, wherein tumor cells that have undergone an EMT are substantially less sensitive to inhibition by IGF-IR kinase inhibitors. Improved methods for treating cancer patients with IGF-1R kinase inhibitors that incorporate the above methodology are also provided. Additionally, methods are provided for the identification of new biomarkers that are predictive of responsiveness of tumors to IGF-1R kinase inhibitors. Furthermore, methods for the identification of agents that restore the sensitivity of tumor cells that have undergone EMT to inhibition by IGF-1R kinase inhibitors are also provided.
Patent DK-1887475-T3 (DK)
Inventor: EDE CLIFFORD
IPC: G06F13/14
Filed: 2004-11-17
Granted: 2012-11-05
Abstract: An interface, for serial data communication between a host and a connected peripheral during a session, comprising: contacts including a power signal contact for supplying power from the connected host to the connected peripheral and at least one data signal contact for serially communicating data between the connected host and connected peripheral; and means configured to periodically check the connection between host and peripheral comprising: transmission means configured to repeatedly send a poll signal via the power signal contact; and reception means configured to receive a reply signal via one of the contacts
Patent DK-1915032-T3 (DK)
Inventor: GEBERT ANTON
IPC: H04R25/00
Filed: 2007-10-11
Granted: 2012-05-07
Abstract: The device (1) has a portable device part (2) at or behind an ear of a user, and an ear piece (3) partially inserted into an auditory canal. A signal processing unit (11) e.g. digital signal processor, in the part amplifies an electrical input signal and generates an electrical output signal that is converted into an acoustic output signal by a receiver (14) arranged in the ear piece. A connecting piece (4) has an electrical conductor (19) to electrically connect the unit and receiver. The piece (4) has a section of a ventilating channel for barometric pressure compensation of the receiver.
Patent DK-2185937-T3 (DK)
Inventor: GRAF ROLF
IPC: G01N33/68
Filed: 2008-09-02
Granted: 2011-09-12
Abstract: The present invention relates to a reliable method of prediction of sepsis in humans after a trauma, wherein the level of pancreatic stone protein/regenerating protein (PSP/reg) is determined in serum, and a high level is indicative of the development of sepsis at early stages of the disease. Furthermore a method of determination of PSP/reg levels in serum is described.
Patent DK-2255464-T3 (DK)
Inventor: LEE YOUNG-DAE
IPC: H04W80/02
Filed: 2009-03-17
Granted: 2018-07-23
Abstract: A method of transmitting PDCP (Packet Data Convergence Protocol) status reports, is performed by a mobile terminal by receiving, from an upper layer, a request for PDCP (Packet Data Convergence Protocol) re-establishment; detecting whether there are any out-of-sequence PDCP SDUs (service data units) stored; and if there is at least one out-of-sequence PDCP SDU stored, allocating a bitmap field of length in bits equal to the number of PDCP SNs from and not including the first out-of-sequence PDCP SDU up to and including a last out-of-sequence PDCP SDU.
Patent DK-2691942-T3 (DK)
Inventor: CARPENTIER BART
IPC: G07F17/00
Filed: 2012-02-17
Granted: 2018-07-23
Abstract: The present application and the resultant patent provide a merchandiser. The merchandiser may include an ambient compartment with at least one ambient product therein, a temperature controlled compartment with at least one temperature controlled product therein, and a rotary internal transport system within the temperature controlled compartment so as to dispense a temperature controlled product in response to an ambient product being placed therein.
Patent DK-3129016-T3 (DK)
Inventor: ELMÉR ESKIL
IPC: C07D417/04
Filed: 2015-04-08
Granted: 2018-09-03
Abstract: The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondrial ATP-output.
Patent DK-3106176-T3 (DK)
Inventor: MÖHLEN MICHAEL
IPC: A61K39/12
Filed: 2012-12-06
Granted: 2018-01-08
Abstract: The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein. The invention further relates to aqueous compositions comprising a protein and an aluminium-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition.
Patent DK-0429207-T3 (DK)
Inventor: FRAZZA MARK STEPHEN
IPC: C08F265/06
Filed: 1990-11-02
Granted: 1996-03-18
Abstract: An aqueous composition, comprising an aqueous dispersion of copolymer particles which have at least two mutually incompatible phases and where the particles have an average particle size of from about 20 to about 70 nanometers, is useful in treating or coating substrates.
Patent DK-0378512-T3 (DK)
Inventor: JANSSEN ROBERT A
IPC: C08J7/04
Filed: 1990-01-04
Granted: 1995-04-03
Abstract: A process for encapsulating a preformed polymeric substrate comprises peroxidizing and hydroperoxidizing the surface of said preformed substrate using ozone and then carrying out a crosslinked graft copolymerization of selected ethylenically unsaturated monomers both on and surrounding (encapsulating) said substrate. Such encapsulation of substrates provides protective coatings, ablative coatings and, particularly, soft skirts for hard contact lenses.
Patent DK-0387194-T3 (DK)
Inventor: JAEGGI KNUT A DR
IPC: C07F9/6512
Filed: 1990-02-27
Granted: 1995-03-20
Abstract: Compounds of the formula I   <IMAGE> (I)  in which R1 is an aromatic radical, n is 0, 1, 2 or 3, X is an oxy group, a thio group which can be oxidized or an imino group which is unsubstituted or has aliphatic substituents, alk1 and alk2 are identical or different divalent aliphatic radicals, and R2 is hydrogen or a monovalent aliphatic radical and salts thereof have properties which regulate calcium metabolism and can be employed for the treatment of diseases connected with disturbances in this metabolism. They are prepared, for example, by reacting a compound of the formula   <IMAGE> (V)  in which X3 is carboxyl with a phosphorylating agent and hydrolysing the primary product.
Patent DK-0442631-T3 (DK)
Inventor: PHAM TU
IPC: C08J9/00
Filed: 1991-01-29
Granted: 1998-12-07
Abstract: A method for the preparation of flexible polymeric foam by reacting a polyisocyanate component with an isocyanate-reactive component comprising at least 50 % by weight of water, the polyisocyanate component comprising at least two polyisocyanate compositions, one of them being a low NCO isocyanate terminated prepolymer and the second being a high NCO polyisocyanate.
Patent DK-0492843-T3 (DK)
Inventor: WILLINGHAM GARY LEWIS
IPC: A01N25/10
Filed: 1991-12-04
Granted: 1995-09-18
Abstract: Solid, stable forms of 3-isothiazolones are disclosed employing a carrier which functions additionally to stabilize the microbicide against chemical decomposition. Said carrier comprises one or more of polysaccharide polymers, cellulose polymers, derivatized cellulose polymers, polymers and copolymers of ethylene oxide and propylene oxide, polyurethane polymers having alternating hydrophobic and hydrophylic moieties, poly(maleic anhydride/methyl vinyl ether), polymethacrylic acid, or naphthalene formaldehyde concentrates.
Patent DK-0442795-T3 (DK)
Inventor: TETON ANDRE
IPC: F28F9/013
Filed: 1991-02-12
Granted: 1994-07-25
Abstract: Dismountable heat exchanger for heat exchange between a fluid flowing inside multiple horizontal hairpin tubes (2), which are mounted on vertical tubular plates (13, 14, 15) orthogonal to the tubes, and a gas loaded with solid particles circulating around these tubes (2) inside an enclosure (1) of rectangular parallelepipedal shape, each tube being connected at the inlet and at the outlet by branches (7, 8) passing through the walls of the enclosure, the said tubular plates (13, 14, 15) being pierced with oval windows (19) forming slots at right angles to the bends of the tubes, and circular openings (20) at right angles to the straight lengths of the tubes, characterised in that the oval windows are pierced at right angles to the bends (11) of the tubes (2) located on the side of the wall traversed by the branches (7, 8) and in that the wall (3) of the enclosure opposite that traversed by the branches (7, 8) is dismountable. The replacement of a tube (2) is very easy and does not require the dismounting of the tubular plates (13, 14, 15). <IMAGE>
Patent DK-0479631-T3 (DK)
Inventor: REGNIER GILBERT
IPC: C07D471/10
Filed: 1991-09-05
Granted: 1995-04-10
Abstract: New spiro[4.5]decane derivatives which can be used as a medicament and correspond to the formula: 
<IMAGE>
 in which X, A, Y, T, Z, R1, R2, R3, R4, R5 and R6 are as defined in the description. 
<??>These derivatives and their physiologically tolerable salts may be used in therapy, in particular in the treatment of dyslipidaemias, atherosclerosis and pathologies in which membrane lipid peroxidation plays a part in initiation and/or aggravation.
Patent DK-0521967-T3 (DK)
Inventor: BAUER CARL-AXEL
IPC: C07C271/44
Filed: 1991-03-14
Granted: 1996-09-09
Abstract: Use of bambuterol or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical preparation with lipid lowering effect.
Patent DK-0515965-T3 (DK)
Inventor: SPIESSER GILBERT
IPC: F16K5/10
Filed: 1992-05-20
Granted: 1995-06-26
Abstract: 1. Valve to control or regulate fluid flow. 2.1 The intention is, by means of a valve, which has a passage for the fluid in which is arranged a valve element which can be rotated by means of an actuating device, to regulate or control a volume flow over a wide range in linear dependence on the rotational movement of the valve element, with a small pressure loss and independently of the inlet pressure. 2.2 The valve element has an aperture which is designed in such a way that its cross-section of passage changes as a third degree function in dependence on the angle of rotation when the valve element is rotated. <IMAGE>
Patent DK-0502812-T3 (DK)
Inventor: HARDMAN NORMAN DR
IPC: A61K47/48
Filed: 1992-01-27
Granted: 1996-09-02
Abstract: The invention concerns recombinant antibodies directed to the extracellular domain of the human growth factor receptor c-erbB-2 comprising a light chain variable domain and a heavy chain variable domain of a monoclonal antibody, monoclonal antibodies directed to c-erbB-2 themselves, a method of manufacture of said recombinant antibodies and said monoclonal antibodies, hybridoma cells secreting said monoclonal antibodies, a method of manufacture of said hybridoma cells, DNA coding for the heavy chain variable domain, for the light chain variable domain and for the recombinant antibody, a method of manufacture of said DNA, hybrid vectors suitable for expression of said DNA, host cells transformed with said DNA, and the use of said recombinant antibodies and said monoclonal antibodies in the diagnosis and treatment of tumors.
Patent DK-0565631-T3 (DK)
Inventor: SCHIRLIN DANIEL
IPC: A61K31/5375
Filed: 1991-12-20
Granted: 1996-10-07
Abstract: This invention relates to novel difluoro statone analogs, to the processes and intermediates useful for their preparation and to their use as anti-vital agents.
Patent DK-0535190-T3 (DK)
Inventor: DUERR WALTER
IPC: F16B39/34
Filed: 1992-04-07
Granted: 1995-12-27
Abstract: PCT No. PCT/DE92/00292 Sec. 371 Date Jan. 15, 1993 Sec. 102(e) Date Jan. 15, 1993 PCT Filed Apr. 7, 1992 PCT Pub. No. WO92/18780 PCT Pub. Date Oct. 29, 1992The invention relates to a member provided with an external screw thread, in which at least in the end portion of the screw thread is provided with at least one plastic part for at least partially covering the same and/or at least partially replacing the same.
Patent DK-0609254-T3 (DK)
Inventor: STAUDENMAIER HORST RALF
IPC: C12R1/645
Filed: 1992-09-25
Granted: 1999-02-08
Abstract: The invention concerns a new method of preparing, by fermentation, compounds of general formula (I) in which R?1 is a hydrogen, fluorine, chlorine or bromine atom.
Patent DK-0558913-T3 (DK)
Inventor: SHETH NITIN VADILAL
IPC: H01S5/00
Filed: 1993-01-25
Granted: 1999-12-13
Abstract: Pharmaceutical delivery systems containing 7-dimethyl 6-deoxy 6-demethyltetracycline or a non-toxic acid addition salt thereof comprising mixtures of a minor proportion of slow-release blended polymer coated spherical granules adapted to release part of the minocycline in a medium having a pH of below 3.9 and the rest in the range of from about 4.0 to about 7.5 and a major proportion of coated or uncoated quick-release granules adapted to release minocycline in a medium having a pH of less than about 3.9 and oral dosage unit form capsules containing the above are provided. These systems and formulations provide enhanced therapeutic blood levels of minocycline for at least about 24 hours when administered to a subject only once-a-day, regardless of whether the patient is fed or fasted. Methods for the preparation of the systems and formulations are provided as well.
Patent DK-0545912-T3 (DK)
Inventor: YANAGISAWA HIROAKI
IPC: A61K/
Filed: 1992-02-21
Granted: 2001-06-18
Abstract: N-Phenylbenzyl imidazole derivs. of formula (I) and their pharmaceutically acceptable salts and esters are new. In (I), R1 = 1-6C alkyl or 3-6C alkenyl; R2 and R3 = H, 1-6C alkyl, 3-6C alkenyl, 3-10C cycloalkyl (opt. polycyclic), aryl(1-6C)alkyl, aryl or aryl fused to 3-10C cycloalkyl; R4 = H, 1-6C alkyl, 1-6C alkanoyl (opt. substd. by one or more halo or 1-6C alkoxy if other than formyl), 3-6C alkenoyl, arylcarbonyl, 1-6C alkoxycarbonyl, tetrahydropyranyl, tetrahydrothiopyranyl, tetrahydrothienyl or tetrahydrofuryl (these 4 opt. substd. by one or more halo or 1-6C alkoxy), SiRaRbRc, 1-6C alkoxymethyl, 1-6C alkoxy(1-6C)alkoxymethyl, halo(1-6C)alkoxymethyl, 1-6C alkyl substd. by at least one aryl, or 1-6C alkanoyl-oxymethoxycarbonyl; Ra, Rb and Rc = 1-6C alkyl or aryl, but not all aryl; R5 = COOH or CONR8R9; R8 and R9 = H, 1-6C alkyl (opt. substd. by at least one (a)) or together are 2-6C alkylene opt. substd. by at least one COOH or alkoxycarbonyl; R6 = H, 1-6C alkyl or alkoxy, or halo; R7 = COOH or tetrazol-5-yl; (a) = aryl, 5-6 membered heterocyclic with 1-4 N, O and/or S, halo, OH, 1-6C alkoxy, COOH, 1-6C alkoxycarbonyl, NH2 or acylamino (acyl = 1-6C alkanoyl or arylcarbonyl); aryl = 6-14C aromatic carbocyclic gp. opt. substd. by at least one of NO2, CN, halo, 6-10C carbocyclic aryl (unsubstd.), 1-6C alkyl or alkoxy, COOH, 1-6C alkoxy-carbonyl, or 1-3C alkylenedioxy or alkylidenedioxy. 23 Cpds. e.g. pivaloyloxymethyl (or (5-methyl-2-oxo -1,3-dioxolen-4-yl)methyl) 4-(1-hydroxy-1-methylethyl) -2-(ethyl, propyl or butyl)-1-(4-(2-tetrazol -5-yl)phenyl)phenyl)methylimidazole -5-carboxylate.
Patent DK-0595424-T3 (DK)
Inventor: RENZI FIORENZO
IPC: G03C1/73
Filed: 1993-10-27
Granted: 1999-01-18
Abstract: A polymerizable liquid composition includes   a polymerizable poly(allyl carbonate) of an aliphatic or cyclo-aliphatic polyol; an organic peroxide generator of free radicals selected from the group of perketals, and possibly   an organic dye and/or an organic photochromic compound.   The compositions can be transformed, by bulk polymerization, into an organic glass which is colourless, or coloured or photochromic, having good optical and mechanical characteristics. <IMAGE>
Patent DK-0720620-T3 (DK)
Inventor: KAUVAR LAWRENCE M
IPC: G01N33/574
Filed: 1994-09-23
Granted: 2000-08-07
Abstract: A method to potentiate the effect of a chemotherapeutic agent in a tumor cell, which method comprises administering to said tumor cell, along with said chemotherapeutic agent, a potentiating amount of a compound of the formula:    <IMAGE>  (1)  or an amide, ester or hybrid amide/ester thereof, wherein X is a hydrocarbon radical optionally substituted on any aromatic moiety contained therein; Y-CO is  gamma -Glu or  beta -Asp and AAC is an amino acid, preferably glycine, phenylglycine,  beta -alanine, alanine or phenylalanine is disclosed. Similar compounds can also be used to selectively exert cytotoxicity versus target cells as compared to nontarget cells and also to elevate the production of GM progenitors in bone marrow of mammalian subjects.
Patent DK-0693443-T3 (DK)
Inventor: AICHER MAX DIPL-ING
IPC: B65D88/12
Filed: 1995-07-11
Granted: 1999-11-08
Abstract: The rectangular skip is open to the top and has a pair of lifting stubs (10) on each of the long sides. These are gripped by the conventional lifting slings attached to the lifting arms to transfer the skip between the vehicle and the ground. Two parallel hollow ducts (11) along the length of the base provide a grip for the forks of a fork lift truck. The skip has vertical end faces and has a length not greater than the width of the transport vehicle. This allows it to be stacked on the vehicle alongside similar skips. Additional grips on the end faces allow the skip to be gripped by hooked ends of lifting/tipping arms. <IMAGE>
Patent DK-0713869-T3 (DK)
Inventor: ANDREAS DR KIENER
IPC: C07D213/61
Filed: 1995-11-23
Granted: 1999-10-25
Abstract: Substd. pyridine derivs. of formula (I) are new: R1 = OH or Cl; (a) X = H or Cl; and R2+R3 = oxo; R4 = OR5; R5 = H, 1-4C alkyl or benzyl; (b) X = H and R2, R3 and R4 are together =NH-NH-; (c) X=R2=H, and R3 and R4 are together -O-; (d) X=R2=H;R3 = OH and R4 = OH or NH2; the cpd. with X=H; R1 = R4 = OH and R2+R3 = OXO is excluded. (I) may be prepd. by e.g. first oxidising nicotine with Pseudomonas or Variovorax, to give 5-succinoyl-2-pyridone and converting this to ester (II; R'5 = 1-4C alkyl or benzyl). The 2-OH is opt. replaced by Cl (esp. reaction with POCl3) and the product cyclised with hydrazine to give cpds. of (b) above. Specified microorganisms are P. putida DSM 8231 or 8236; P. fluorescens DSM 8235; P. sp. DSM 8653 or V. paradoxus DSM 8244. These can tolerate a high nicotine concn. (pref. 5-20 g/l) and provide high yields and concn. of product.
Patent DK-0673007-T3 (DK)
Inventor: PINCHEN STEPHEN PAUL
IPC: G08B13/24
Filed: 1995-03-09
Granted: 2002-05-27
Abstract: A tagging material (100) comprises a pressure sensitive adhesive tape (101,104) incorporating electromagnetic sensor material (105) whose presence can be detected. Tags (400) are cut from the tagging material as the tagging material (100) and articles (29) are conveyed along converging paths (14,51) and are adhered to the articles by the adhesive of the tape by means of apparatus comprising a tagging material feeding means (200) and an applicator head (19).
Patent DK-0699754-T3 (DK)
Inventor: SKOLNICK MARK H
IPC: C12N15/09
Filed: 1995-08-11
Granted: 2001-02-26
Abstract: The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of which cause susceptibility to cancer, in particular breast and ovarian cancer. More specifically, the invention relates to germline mutations in the BRCA1 gene and their use in the diagnosis of predisposition to breast and ovarian cancer. The present invention further relates to somatic mutations in the BRCA1 gene in human breast and ovarian cancer and their use in the diagnosis and prognosis of human breast and ovarian cancer. Additionally, the invention relates to somatic mutations in the BRCA1 gene in other human cancers and their use in the diagnosis and prognosis of human cancers.
Patent DK-0752008-T3 (DK)
Inventor: STEMMER WILLEM P C
IPC: C12Q1/6811
Filed: 1995-02-17
Granted: 2002-06-17
Abstract: The present invention provides a population of polynucleotides resulting from shuffling sequences from substrate polynucleotides encoding antibody chains, whereby the population of polynucleotides comprises recombinant polynucleotides encoding antibody chains having different combinations of heavy chain CDRs and/or light chain CDRs than are encoded by the substrate polynucleotides. Such a population of polynucleotides may be employed to provide an antibody display library.
Patent DK-0798978-T3 (DK)
Inventor: VANDAMME PAUL
IPC: A47G21/02
Filed: 1995-12-13
Granted: 1999-06-07
Abstract: PCT No. PCT/EP95/05040 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 13, 1995 PCT Pub. No. WO96/18334 PCT Pub. Date Jun. 20, 1996A server for picking up and discharging strand shaped material, like spaghetti. The invention has the object to provide a server for the easy bringing over of strand shaped material, like spaghetti, from a pot, pan or the like holder into another holder and/or on dishes. Therefore the server according to the invention is characterized by a screw-shaped food engaging portion.