baber/WOPTO huggingface dataset:
Patent ZA-909528-B (ZA)
Title: Process for the preparation of vancomycin
Inventor: NAGY MARIANN
IPC: C07K9/00
Filed: 1990-11-27
Abstract: PCT No. PCT/HU90/00079 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed Nov. 27, 1990 PCT Pub. No. WO91/08300 PCT Pub. Date Jun. 13, 1991.The invention relates to a process for preparation of the vancomycin antibiotic in a microbiological way by aerobic fermentation, by using a strain belonging to the Micropolyspora species in a culture-medium containing assimilable carbon and nitrogen sources as well as mineral salts. According to the invention as microorganisms the aminoglycoside-resistant NCAIM 001092 and NCAIM 001093 mutants of the strain belonging to the Micropolyspora orientalis species are used. Nitrates are suitable mineral salts in the fermentation. Soy flour, glycerol, calcium gluconate, starch are useful carbon sources. The fermentation is carried out preferably at a temperature of 29 DEG -30 DEG  C. The vancomycin antibiotic produced in the fermentation is separated by using reverse osmosis and ultrafiltration following ion-exchange chromatography.
Patent ZA-925613-B (ZA)
Title: Beta-Substituted cinnamic acid derivative
Inventor: SAUTER HUBERT
IPC: A01N43/56
Filed: 1992-07-27
Abstract: Derivatives of  beta -substituted cinnamic acid of the general formula 1 <IMAGE>  in which   R<1> denotes optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, and in which R<1> can also denote chlorine or bromine,   -X- represents the groups -O-, -S-, <IMAGE>   m denotes 0 or 1, -Y represents the groups -OR<4>, -O-N=CR<5>R<6>, -NR<7>R<8>, -N(OR<9>)R<10> or -Sr<11>, where the abovementioned substituents R<2> to R<11> denote optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl, and for the radicals R<2>, R<3> and R<5> to R<11> can also denote hydrogen, Z denotes halogen, nitro, cyano, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted heteroarylalkyl, optionally substituted heteroaryloxyalkyl, optionally substituted heteroarylthioalkyl, optionally substituted alkenyl, optionally substituted aralkenyl, optionally substituted aryloxyalkenyl, optionally substituted arylthioalkenyl, optionally substituted heteroarylalkenyl, optionally substituted heteroaryloxyalkenyl, optionally substituted heteroarylthioalkenyl, optionally substituted alkynyl, optionally substituted arylalkynyl, optionally substituted heteroarylalkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted arylazo, optionally substituted acylamino, -OR<12>, -SR<13>,-SOR<14>, -SO2R<15>, -COOR<16>, -CONR<17>R<18>, -COR<19>, -CR<20>=NR<21>, -N=CR<22>R<23>, -CR<24>=N-OR<25>, -CR<25>R<26>-O-N=CR<27>R<28>, -CH2-OCOR<39> or -NR<37>R<38>, where the groups R<12> to R<28>, and R<38> and R<39> denote hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aralkyl, optionally substituted heteroarylalkyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted heteroaryloxyalkyl or optionally substituted heteroarylthioalkyl and R<37> denotes hydrogen or C1-C4-alkyl  and in which   U, V, W denote hydrogen or have one of the meanings mentioned for Z  or in which two of the groups Z, U, V or W in adjacent positions of the phenyl ring optionally together form an optionally substituted five- or six-membered, aromatic or aliphatic ring fused to the phenyl ring, which can optionally contain one to three heteroatoms (N, S, O).
Patent ZA-931261-B (ZA)
Title: 2,3,4,5-Tetrahydro-1H-3-benzazepines having anti-psychotic activity and synthesis of alpha-substituted-aryl-acetamides.
Inventor: BERGER JOEL G
IPC: C07D217/24
Filed: 1993-02-23
Abstract: PCT No. PCT/US93/01425 Sec. 371 Date Aug. 19, 1994 Sec. 102(e) Date Aug. 19, 1994 PCT Filed Feb. 23, 1993 PCT Pub. No. WO93/16997 PCT Pub. Date Sep. 2, 1993.A novel process for the preparation of  alpha -substituted arylacetamides wherein the substituent is an aromatic group or a 1-alkenyl or 1-cycloalkenyl group and wherein the nitrogen atom carries no hydrogen atoms comprises the reaction of an arylacetamide having one or two hydrogen atoms on the  alpha -carbon atom, wherein the nitrogen atom carries no hydrogen atoms, with a strong base in an inert aprotic organic solvent, followed by reaction with a zerovalent transition metal catalyst and then with a compound of the formula R4-X, wherein R4 is selected from aromatic groups, 1-alkenyl groups and 1-cycloalkenyl groups and X is a particular leaving group, especially a triflate group. The  alpha -substituted arylacetamides are useful as intermediates in the preparation (by reduction) of  alpha -substituted arylethylamines, e.g., 1-substituted-2,3,4,5-tetrahydro-1H-3-benzazepines, having pharmacological activity. Certain benzazepines wherein the 1-substituent R4 is 1-(1-cycloalkenyl) are novel.
Patent ZA-933993-B (ZA)
Title: Novel estradiol derivative-chlorambucil conjugate, process for preparing the same, and pharmaceutical composition.
Inventor: TAMURA FUMIO
IPC: C07J41/00
Filed: 1993-06-07
Abstract: An estradiol derivative-chlorambucil conjugate of the formula (I):   <CHEM> wherein R<1> is alkyl or alkoxyl of 1 to 4 carbon atoms; R<2> is acyl, dansyl, or alkyl; R<3>, R<4>, and R<5> independently are H, oxo, OH, or acyloxy; m is an integer of 1 to 3; and n is an integer of 0 to 3; provided that when n is 0, all of R<3>, R<4>, and R<5> are not H at the same time, and at least one of R<3>, R<4>, and R<5> is a group other than H and OH; and further, when n is 2 or 3, the groups R<1> are the same or different; a process for preparing the same, and a pharmaceutical composition containing the conjugate are described.
Patent ZA-939360-B (ZA)
Title: 3,5-substituted aminobenzoylguanidines process for their preparation their use as a medicament or diagnostic and medicament containing them
Inventor: LANG HANS-JOCHEN
IPC: A61P9/00
Filed: 1993-12-14
Abstract: Benzoylguanidines of the formula I <IMAGE>  having one of the substituents R(1), R(2), R(3) or R(4):  an amino group <IMAGE> where R(5) and R(6) are, inter alia, H or alkyl, or R(5) and R(6), together with the N atom, are a 5-7-membered ring, and the other substituents R(1), R(2), R(3) and R(4) are in each case: H, Hal, CN, CF3, NO2, CF3-O-, CmF2m+1-CH2-O- or R(11)-CqH2q -Xp-, X is O or NR(12) and R(11) is H, (cyclo)alkyl or phenyl, with R(1) and R(4) not being hydrogen simultaneously,  are described. The compounds I possess very good anti-arrhythmic and cardio-protective properties but do not have any undesirable salidiuretic properties. In addition, they exhibit protective properties against ischaemically-induced damage in vivo and in vitro in various organs, and also gastroprotective properties as a result of inhibiting gastric acid secretion. In addition to this, they are notable for their inhibitory effect on the proliferation of cells.
Patent ZA-939729-B (ZA)
Title: Base blade of fiber-reinforced plastic for circular saw blades and/or abrasive cutting disks
Inventor: MUMMENHOFF HEINRICH
IPC: B28D1/12
Filed: 1993-12-28
Abstract: The present invention relates to a blade body for circular sawblades and/or abrasive cutting wheels, comprising a circular disc body (2) consisting at least partially of a plastics material (6) reinforced with embedded fibres (4). The fibres (4) are arranged in a plurality of fibre layers (16, 18) which lie one above the other, are bonded cohesively or adhesively, are planar, shaped as circular discs and concentric to the disc body (2). In a first type of fibre layer (16), the fibres (4) are aligned rectilinearly in an at least approximately radial direction - with respect to the disc body (2) - and are arranged in a uniform distribution over the circumference. In a second type of fibre layer (18), the fibres (4) have an at least approximately circular path which is substantially concentric to the disc body (2), the two types of fibre layers (16, 18) being arranged in the disc body (2) with a distribution chosen in dependence on the size of the disc body (2). <IMAGE>
Patent ZA-957153-B (ZA)
Title: Liquid containing and dispensing package
Inventor: HAFFNER EUGENE F
IPC: B65D25/48
Filed: 1995-08-25
Abstract: A liquid dispensing fitment for use on a container having a neck comprises a plastic body which has an inner wall defining an axial spout extending from within the neck of a container and axially beyond the end of the neck. The body has an outer annular wall spaced from the spout and connected to the spout by an integral annular connecting portion. The spout extends axially beyond the outer wall and has an upper generally C-shaped cross section defining an opening and a lower annular cross section. The annular connecting portion is inclined with respect to the axis of the spout and has its lowermost portion aligned with the opening of said C-shaped portion of said spout. The outer wall has an axial opening extending from a position aligned with the juncture of the C-shaped portion and annular portion of the spout through the annular connecting portion to define a combined drain back opening and a near empty pour out hole. The fitment is provided with means on the upper end of the outer wall for engaging the neck of the container. The lower portion of the spout is substantially smooth in an axial direction to facilitate drain back. The lower portion of the spout has an inner surface formed with an integral axial rib aligned with the axial opening in the outer wall to facilitate manufacture. The wall of the fitment is provided with an axially extending opening that extends from a position aligned with the junction of the C-shaped portion and annular portion to define a combined drain back opening and near empty pour out hole.
Patent ZA-979154-B (ZA)
Title: Apparatus for controlling gas temperature
Inventor: CONEY MICHAEL WILLOUGHBY ESSEX
IPC: F04B39/06
Filed: 1997-10-13
Abstract: An apparatus is provided for controlling gas temperature during compression or expansion. The apparatus comprises a chamber for containing gas, a piston for changing the volume of gas in the chamber, a plurality of atomisers for spraying liquid into the chamber and means for delivering liquid to the atomisers. Each atomiser comprises a spray aperture and means defining a flow path for imparting rotary motion to the flow of liquid about the axis of the aperture so that on leaving the aperture the liquid divides into a conical spray. Spray apertures are positioned adjacent one another and the axes of adjacent spray apertures are oriented such that their respective sprays intersect at a position proximate at least one of the respective adjacent spray apertures.
Patent ZA-986701-B (ZA)
Title: Austenitic stainless steel with a very low nickel content
Inventor: CHESSERET LAURENT
IPC: C22C38/00
Filed: 1998-07-28
Abstract: A low nickel content austenitic stainless steel has the composition (by wt.) less than 0.1% C, 0.1-1% (exclusive) Si, 5-9% (exclusive) Mn, 0.1-2% (exclusive) Ni, 13-19% (exclusive) Cr, 1-4% (exclusive) Cu, 0.1-0.40% (exclusive) N, 5 x 10<-4>-50 x 10<-4>% (exclusive) B, less than 0.05% P and less than 0.01% S. Preferably, both the ferrite index (IF1) and the martensite stability index (IS) are less than 20, where IF1 = 0.034 x x<2> + 0.284 x x - 0.347 and IS = 0.0267 x y<2> + 0.4332 x y - 3.1459, in which x = 6.903 x Ä-6.998 + Cr% - 0.972 x (Ni% + 20.04C% + 21.31N% + 0.46Cu% + 0.08Mn%)Ü and y = 250.4 - 205.4C% - 101.4N% - 7.6Mn% - 12.1Ni% - 6.1Cr% - 13.3Cu%.
Patent ZA-997211-B (ZA)
Title: Oscillator and telecommunications system with such an oscillator.
Inventor: RITTER RUDOLF
IPC: H03B28/00
Filed: 1999-11-19
Abstract: The oscillator integrated into a chip can generate an electrical clock signal with a reference signal, wherein the chip contains the following components: at least one laser transmitter, which can generate two coherent light signals with a differing optical transmission frequency, a coupler, in order to merge the two light signals, an electromagnetic converter, which can generate an electrical signal, whose frequency corresponds to the distance between the two transmission frequencies, a frequency divider, which can divide the frequency of the electrical signal in order to deliver a clock signal with a lower frequency. The oscillator can be inserted into a SIM card, for example, in order to make possible a non-falsifiable determination of the connection duration.
Patent GB-2343708-B (GB)
Title: Plastic support devices especially for pipes and cables
Inventor: PHILLIPS RAYMOND JOHN
IPC: F16B2/22
Filed: 1998-05-08
Granted: 2000-10-11
Abstract: A rod-engaging support device (<HIL><PDAT>1</BOLD><PDAT>) is formed from plastics material. The body (<HIL><PDAT>2</BOLD><PDAT>) of the device (<HIL><PDAT>1</BOLD><PDAT>) supports a fitting e.g. rod connector, suspension hook or munsen ring, which fitting may be integral or removably securable thereto. The device (<HIL><PDAT>1</BOLD><PDAT>) further incorporates rod engagement means (<HIL><PDAT>4, 5</BOLD><PDAT>) wherein the rod is received by the engagement means (<HIL><PDAT>4, 5</BOLD><PDAT>) in a first position and following relative rotation of the device (<HIL><PDAT>1</BOLD><PDAT>) with respect to the rod, the rod is gripped by the engagement means (<HIL><PDAT>4, 5</BOLD><PDAT>) in a second position.</PTEXT>
Patent GB-2365770-B (GB)
Title: Antifungal ketoconazole composition for topical use
Inventor: WHITEFIELD MARTIN
IPC: A61K9/00
Filed: 2000-08-18
Granted: 2002-07-31
Abstract: A pharmaceutical composition suitable for topical application comprising ketoconazole in a solution which comprises: (i) 13 to 50 wt % water; (ii) 45 to 85 wt % of an alcohol having a boiling point of less than 100° C.; and (iii) 2 to 30 wt % of a non-volatile, water miscible, non-ionic surface active agent; the ketoconazole being present in an amount of 0.5 to 3 st % relative to components (i), (ii) and (iii).
Patent GB-2358187-B (GB)
Title: Treatment of carbonaceous material
Inventor: PEARSON FREDERICK
IPC: F23G1/00
Filed: 2000-09-14
Granted: 2004-03-24
Abstract: A process for the treatment of organic matter, comprises the steps of preliminary microwave irradiation in an oxygen-depleted atmosphere to give a black ash-like residue, followed by combustion of the residue to give a white ash. Hence the emissions of carcinogens such as dioxins are substantially reduced as are heavy metals such as Mercury and Cadimum. The apparatus ( 11 ) comprises a single chamber ( 12 ) in which both steps of the process are performed. The apparatus ( 11 ) also comprises means for generating nitrogen- or oxygen-depleted air as well as scrubbers ( 2 ), filters, condensers and the like for treating the gaseous products (carbon dioxide and steam) of the process. The apparatus ( 11 ) may be of a portable and modular nature-and may optionally include a cremulator.
Patent GB-2389479-B (GB)
Title: Method of serving out video over a network of video servers
Inventor: SLATER ALASTAIR MICHAEL
IPC: H04N5/00
Filed: 2002-06-07
Granted: 2005-12-28
Abstract: A method of serving out video over a network of video servers includes evaluating a capacity of the network as a whole to serve out specific video items by establishing, for each video server in the network, an established ability of each server to serve out the specific items that are potentially servable from each video server. The method further includes using the established abilities of each video server to evaluate an overall capability of the network as whole to serve out each of the specific video items. The method also includes varying the overall capability to serve out at least a selected one of the specific video items in accordance with the overall capability of the network.
Patent GB-2394588-B (GB)
Title: Security system
Inventor: WOODYARD PETER RICHARD
IPC: H04M1/72424
Filed: 2000-11-21
Granted: 2004-06-30
Abstract: A mobile phone 10 is coupled by an edge connector 18 to a detector unit 20 which may include a passive infra-red sensor 22 and a remote PIR sensor 28. The combined phone and detector can be mounted inside a vehicle to respond to an intruder. When an alarm condition is detected, the phone automatically calls a preset number or stores information for later transmission. The device may be associated with a GPS receiver and may be incorporated into portable apparatus such as a computer and respond to movement or unauthorised use. Alternatively, a detector may be mechanically connected to a mobile phone by an arrangement including an electromagnetically operated plunger for pressing a preset key on the keypad of the phone.
Patent GB-2418313-B (GB)
Title: Receiving system for determining a target angle of deviation
Inventor: GOTTWALD FRANK
IPC: G01S13/931
Filed: 2005-09-07
Granted: 2007-03-28
Abstract: A receiving array with several antenna columns is provided to determine the target angle of deviation in a pulse radar system. There is one downlink mixer (43) for each antenna column and a delay line (9) between at least one antenna column and the downlink mixer. An evaluation unit (6) determines the phase difference between the output signals of the downlink mixers corresponding to the Doppler shift of a radar target. From this the angular position of the target can be determined. The received signal may be scanned in order to determine the Doppler shift and hence the speed of the target.
Patent GB-2163274-B (GB)
Title: Low temperature reduction process for photomasks
Inventor: ERNSBERGER FRED MARTIN
IPC: G03F1/54
Filed: 1984-11-21
Granted: 1987-02-04
Abstract: Glass photomasks having a high resolution stain pattern for use in photofabrication processes are made by migrating stain-producing ions into the surface of a glass substrate, and reducing and agglomerating the stain- producing ions in the presence of pure hydrogen under pressure at relatively low temperatures to produce a high resolution stain pattern. <IMAGE>
Patent GB-2154561-B (GB)
Title: Closure for a container
Inventor: KELSEY STEPHEN FREDERICK
IPC: B65D17/50
Filed: 1985-02-01
Granted: 1987-04-29
Abstract: @ A plastics closure for a can end of the kind having a pouring aperture and a venting aperture comprises a first connecting member (51) which connects a vent plug (52) and a pouring aperture plug (53) and is extended to form a pull tab (60) acting directly on the vent plug. The plugs are rupturably sealed over the respective apertures of collar portions 55, 56) connected by a second connecting member (54) and fitting in the venting aperture and the pouring aperture. Flexible tie means (57A, 57B) extend from the pouring aperture plug (53) to flexible hinges (58) joined to the venting aperture collar (55). When the pull tab (60) is lifted the vent plug (52) is torn away from the venting aperture collar (55) to achieve dry venting before the pouring aperture plug (53) is torn away to complete opening for pouring. The plugs (52, 53) are retained captive by the tie means for reclosure of the apertures.
Patent GB-2155483-B (GB)
Title: Insulated wires
Inventor: SAWYER DUDLEY NOEL
IPC: H01B3/44
Filed: 1985-03-07
Granted: 1987-07-22
Abstract: An insulated wire with greatly impoved scrape abrasion resistance is distinguished by a flexible thermoplastic PVC composition containing an impact modifying agent such as styrene/butadiene/acrylonitrile terpolymer or styrene/butadiene/methacrylate terpolymer.
Patent GB-2200589-B (GB)
Title: Dryer fabric seaming
Inventor: WHITNEY DAVID P
IPC: F16G3/02
Filed: 1987-12-11
Granted: 1990-06-13
Abstract: A flat woven papermakers' dryer fabric is disclosed and also a method of making a seam in a flat woven papermakers' dryer fabric, each fabric end (12, 13) being provided with complementary parts of a temporary fastening means, respective one parts being provided in the form of strips (31, 32, 34, 34) extending respectively longitudinally of the seam adjacent each fabric end (12, 13) on each face thereof, the other part of the complementary parts of the temporary fastening means (33) is arranged, on a selected face of the belt, to overlie two of said one part of the complementary fastening means so as to maintain the interdigitated condition of said formations. Said parts of said temporary fastening means (31, 32, 34, 34 and 33) can be selectively separable and along the length of the seam to permit adjustment of the degree of interdigitation of the formations position. <IMAGE>
Patent GB-2248840-B (GB)
Title: Substrate carrying ligands to screen for biological activity
Inventor: PIRRUNG MICHAEL C
IPC: C12Q1/68
Filed: 1991-12-06
Granted: 1993-12-01
Abstract: A detection apparatus for determining a fluorescence pattern on a substrate and capable of discriminating an area exhibiting fluorescence of less than about 2.5x10<4>  mu m<2>, said apparatus comprising a light source for directing light at the substrate, means for detecting fluoresced light from the substrate, and means for determining the location of the fluorescent light.
Patent HU-211093-B (HU)
Title: Process for production of panchreatin micropellets
Inventor: SOBE ALWIN
IPC: A61K9/16
Filed: 1993-08-04
Abstract: Micropellet cores which contain pancreatin and can be coated with an enteric film and which have a spherical or ellipsoidal shape, where the diameter of the sphere or the minor axis is in the range 0.7-1.4 mm, in particular 0.8-1.2 mm, and which have a particle size distribution in which at least 80 % of the micropellet cores have a ratio of the minor axis to the major axis in the range from 1:1 to 1:2, are described. Also described is a process for the production of these pancreatin micropellets.
Patent HU-214133-B (HU)
Title: A method, an electrode system and an assembly for heating media flowing through an insulating pipe
Inventor: PEDERSEN IB OBEL
IPC: A23L3/01
Filed: 1992-05-27
Abstract: A method of heating media flowing through an insulating pipe by means of high-frequency electrical power. The medium is fed through a pipe of a substantially electrically non-conducting material and only presenting minor dielectric losses, and around which two ring electrodes are arranged at such a mutual axial distance that the two electrode rings are mutually spaced by a predetermined pipe length connecting said electrodes to the terminals of an HF generator and applying an HF voltage from the HF generator. In this manner a uniform and efficient heating is obtained of the flowing medium or fluid (granulate, liquid or gas) without said medium necessarily getting into direct contact with a heating means and without said medium escaping from its conveying pipe. The latter is very advantageous in connection with many uses, such as when toxic or aggressive media apply, and also when sensitive media are involved which do not endure getting in contact with the atmosphere.
Patent HU-213792-B (HU)
Title: Process and arrangement for securing facade slabs
Inventor: RIMBACH FRANK
IPC: E04F13/21
Filed: 1993-11-25
Abstract: A process and arrangement are disclosed for securing façade slabs on buildings made of slabs, preferably for securing façade slabs located on the building slabs over an insulating layer. The object of the invention is to provide a process and an arrangement for securing façade slabs on buildings and an associated device which allow even heavy slabs to be safely and economically secured and which to a large extent prevent the secured slabs and the building from being additionally stressed. For this purpose, a slotted cylindrical sleeve is arranged in a bore designed in the façade slab as a throughbore and in the building slab as a blind bore, and a tapering metal piece is arranged in the slotted sleeve.