baber/WOPTO huggingface dataset:
Patent NO-20141458-A1 (NO)
Title: Undervannsplattform
Inventor: SCHRAMM RAINER
IPC: B65D88/78
Filed: 2014-12-02
Abstract: Et undersjøisk tankelement omfatter minst en tankseksjon (1), der tankseksjonen(e) danner en sylindrisk betongtank (2) lukket ved sine motstående ender av to endekapsler (12). Tankelementet omfatter videre en rektangulær struktur (3, 4, 5) som omgir den sylindriske tanken (2), og en forbindelse (150, 160) mellom den rektangulære strukturen (3, 4, 5) og den sylindriske tanken (2) som tillater en bevegelse av veggen til den sylindriske tanken (2) innefor forhåndsbestemte grenser for utbøying av den rektangulære strukturen (3, 4, 5). Permanent ballast (6, 7) og en ballast tank (8) styrer oppdrift og sikrer statisk stabilitet. Etteroppspenningskabler gjennom kanaler 9 binder delene sammen til et tankelement, og tankelementene til et system. Flere anvendelser, inkludert en undervannslekter, et undersjøisk hydro-elektrisk anlegg og en svevende lagertanksammenstilling er beskrevet.
Patent NO-20180163-A1 (NO)
Inventor: ROGALA THOMAS
IPC: E21B37/06
Filed: 2018-02-01
Abstract: A positive displacement metering system measures the rate of travel of a free piston in a cylinder of known volume to determine the flow rate of a fluid out of the cylinder. The system may also measure and record the inlet and outlet pressures or the differential pressure between the fluid inlet and outlet. The control program positions a four-way valve which may function as an adjustable metering orifice in response to the measured flow rate and/or changes in the inlet and outlet pressures to achieve the desired flow rate. At the end of each stroke, the four-way valve is repositioned to reverse fluid flow through the metering cylinder. The system may revise the valve position settings for both forward and reverse strokes based on the measured time required for a full stroke of the piston within the cylinder at a certain valve position or a measured rate of movement of the free piston.
Patent PE-20000252-A1 (PE)
Title: Metodo para producir quimicos de molibdeno a partir de materiales sulfidicos
Inventor: MAY WILLIAM A
IPC: C22B34/34
Filed: 1999-02-08
Abstract: METODO PARA RECUPERAR MOLIBDENO DESDE UNA SOLUCION QUE LO CONTIENE, EL CUAL CONSISTE EN : i) CONVERTIR UNA PARTE DEL MOLIBDENO QUE CONTIENE LA SOLUCION EN CRISTALES DE HEPTAMOLIBDATO DE AMONIO Y DIMOLIBDATO AMONICO, Y RETIRARLOS; ii) PONER EN CONTACTO DICHA SOLUCION, CON ACIDO SULFURICO PARA REDUCIR EL pH A UN VALOR NO MAYOR A 4; iii) FILTRAR LA SOLUCION (ii) PARA SEPARAR EL POLIMOLIBDATO DE DICHA SOLUCION Y FORMAR UN PRECIPITADO RECUPERADO Y UN FILTRADO; iv) LAVAR EL PRECIPITADO RECUPERADO EN (iii) CON UNA SOLUCION LAVATIVA DE MOLIBDATO AMONICO PARA RETIRAR UNA PARTE DEL SULFATO AMONICO TOTAL EN EL PRECIPITADO; v) SECAR Y CALCINAR EL PRECIPITADO RECUPERADO EN (iv) PARA RETIRAR EL AMONIACO Y EL AGUA, OBTENIENDO UN PRECIPITADO RICO EN MOLIBDENO; vi) PONER EN CONTACTO EL FILTRADO OBTENIDO EN (iii) CON UN SULFURO EN CONDICIONES SUFICIENTES PARA PRECIPITAR SULFURO DE MOLIBDENO; vii) EVAPORAR EL AGUA DEL FILTRADO (vi) PARA DAR SULFATO AMONICO FERROSO GRANULADO
Patent PE-20000345-A1 (PE)
Title: Inhibidores enzimaticos
Inventor: UNDERINER TODD LAURENCE
IPC: A61P3/06
Filed: 1999-03-12
Abstract: SE REFIERE A COMPUESTOS DE FORMULA I, DONDE B1 ES H, METILO, ETILO, PROPILO, ENTRE OTROS; B1 Y B2 FORMAN UN ANILLO DE 5-6 MIEMBROS; B2 ES H, METILO, ETILO, PROPILO; X ES -CH2-, -NH-; Z ES UN CARBOCICLO OPCIONALMENTE SUSTITUIDO, HETEROCICLO; L1, L2 Y L3 SON NH, O, S, CF2, ALQUIL, NHSO2R1, COR2, CO-R3-O-, CO-R4-S, CO-R5-NH, NH-R6-, O-R7, CO-O-R8, CONH-R9, NHCOR10, -OCOR11, -COCHR12NR13-Y; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 SON ALQUIL, ALQUENIL, CICLOALQUIL, ARIL, ENTRE OTROS; R12 ES H, ALQUILO, ALQUENILO, -AA; -AA ES UNA CADENA LATERAL DE AMINOACIDO; R13 ES H; R12 Y R13 FORMAN UN HETEROCICLO; Y ES -COCHR14NR15; R14 ES H, ALQUILO, ALQUENILO, ENTRE OTROS; R15 ES H; R14 Y R15 FORMAN UN HETEROCICLO, L4 ES CO, P ES POLIMERO, POLI(ALQUILENOXIDO); n ES 1-100; Q ES O, A ES ALQUILO, ALQUENILO, CICLOALQUILO, ARILO, Z` ENTRE OTROS; Z' ES UN CARBOCICLO, HETEROCICLO, COZ', COR15-CF3; R15 ES ALQUIL, UN GRUPO a; EXCEPTO EL COMPUESTO DE FORMULA II. TAMBIEN SE REFIERE A UN COMPUESTO PREFERIDO III. EL COMPUESTO I ES INHIBIDOR DE CARBOXIPEPTIDASA A, QUIMOTRIPSINA, ELASTASA, TRIPSINA CON ABSORCION LIMITADA A TRAVES DE LA PIEL POR LO QUE PUEDE SER UTIL EN UNA COMPOSICION PARA EL CUIDADO PERSONAL, PARA EL CUIDADO DE LA PIEL O PUEDE SUMINISTRARSE EN UN ARTICULO ABSORBENTE AL SER UTIL PARA EL TRATAMIENTO DEL SARPULLIDO POR CAUSA DEL PANAL
Patent PE-52599-A1 (PE)
Title: Vacuna viva recombinante aviaria, que comprende como vector el virus de la laringotraqueitis infecciosa
Inventor: AUDONNET JEAN-CHRISTOPHE
IPC: C07K14/03
Filed: 1997-06-27
Abstract: CARACTERIZADA PORQUE COMPRENDE Y EXPRESA UN PLASMIDO HETEROLOGO DEFINIDO ENTRE LOS NUCLEOTIDOS 1624 Y 3606 EN LA SEQ.ID NO:5, INSERTADA POR INSERCION SIMPLE O DESPUES DE SUPRESION TOTAL O PARCIAL DEL SITIO DE INSERCION EN EL QUE APARECE UN CUADRO ABIERTO (CAJA) DE LECTURA QUE COMPRENDE UN PROMOTOR , DOS O MAS GENES SEPARADOS DOS A DOS POR UN IRES (SITIO DE ENTRADA DEL RIBOSOMA INTERNO) Y UNA SENAL DE POLIADENILACION; PARA EXPRESAR EL PLASMIDO EL VECTOR COMPRENDE UN PROMOTOR EUCARIOTICO FUERTE CMV INMEDIATO TEMPRANO (IE) PREFERIBLEMENTE EL CMVIE MURINO O HUMANO. TAMBIEN SE REFIERE A DOS PLASMIDOS INSERTADOS EN EL SITIO DE INSERCION BAJO EL CONTROL DE PROMOTORES EUCARIOTICOS DIFERENTES, LA PRIMERA SECUENCIA ASOCIADA AL PROMOTOR CMVIE CON OTRO PROMOTOR DE MANERA QUE SUS EXTREMOS 5` SEAN ADYACENTES; QUE EXPRESAN UN POLIPEPTIDO ANTIGENICO, ELEGIDO DEL GRUPO QUE COMPRENDE PROTEINAS HN Y F DEL VIRUS DE LA ENFERMEDAD DE NEWCASTLE (NDV) Y LA GLICOPROTEINA gB, gD, GH+gL DEL VIRUS DE LA ENFERMEDAD DE MAREK (MDV), LA Vp2 DE LA ENFERMEDAD DE GUMBORO (IBDV) Y LAS PROTEINAS S Y M DEL VIRUS DE LA BRONQUITIS INFECCIOSA IBV
Patent PE-87998-A1 (PE)
Title: DERIVADOS DE BENZO [g] QUINOLINA
Inventor: GULL PETER
IPC: C07D417/12
Filed: 1997-07-07
Abstract: SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: "A" Y "B" SON H O FORMAN JUNTOS UN ENLACE ADICIONAL; "X" ES CH2 o CO; "Y" ES O, S, NR1, CH2 o O-CH2, EN DONDE R1 ES H o ALQUILO C1-C6, DE PREFERENCIA ES CH3; R ES PIRIDIL, IMIDAZOL O 1,2,4 TRIAZOL, ENTRE OTROS. TAMBIEN SE REFIERE AL PROCEDIMIENTO DE PREPARACION DE (I), QUE COMPRENDE CONVERTIR EL GRUPO ALCOXI DE (II), EN DONDE R2 ES ALQUILO C1-C4, EN UN GRUPO HIDROXI. LOS COMPUESTOS OBTENIDOS SON UTILES EN EL TRATAMIENTO DEL GLAUCOMA
Patent PE-3699-A1 (PE)
Title: Conjunto de circuito de retardo hibrido de detonador electronico
Inventor: BRENDAN M WALSH
IPC: F42B3/12
Filed: 1997-12-05
Abstract: UN DETONADOR QUE COMPRENDE: A) UNA CAJA CON UN EXTREMO CERRADO Y OTRO ABIERTO, TENIENDO ESTE ULTIMO LAS DIMENSIONES Y CONFIGURACION APROPIADAS PARA SER CONECTADO A UN MEDIO DE TRANSMISION DE SENAL DE INICIACION; B) UN MEDIO DE TRANSMISION DE SENAL ELECTRICA DE INICIACION DENTRO DE LA CAJA PARA ENTREGARLA AL TERMINAL DE ENTRADA DEL CIRCUITO DE RETARDO; C) UN CIRCUITO DE RETARDO QUE INCLUYE: 1) UN TERMINAL DE ENTRADA PARA RECIBIR UNA CARGA DE ENERGIA ELECTRICA, 2) UN MEDIO DE ALMACENAMIENTO CONECTADO AL TERMINAL DE ENTRADA PARA RECIBIR Y ALMACENAR DICHA CARGA, CON UNA CAPACITANCIA ENTRE 0,22 Y 1 MICROFARADIO CON CLASIFICACION NOMINAL ENTRE 50v Y 150v Y UNA CONSTANTE DE TIEMPO ENTRE 0,2 Y 15 MICROSEGUNDOS, 3) UN CIRCUITO CONMUTADOR INTEGRADO DIELECTRICAMENTE AISLADO QUE CONECTA EL MEDIO DE ALMACENAMIENTO AL TERMINAL DE SALIDA LIBERANDO LA ENERGIA ALMACENADA EN ESTE A DICHO TERMINAL DE SALIDA EN RESPUESTA A UNA SENAL DE UN CIRCUITO CONTADOR, 4) UN TERMINAL DE SALIDA CONECTADO AL MEDIO DE ALMACENAMIENTO A TRAVES DEL CIRCUITO CONMUTADOR, Y 5) UN CIRCUITO CONTADOR CONECTADO AL CIRCUITO CONMUTADOR PARA CONTROLAR LA LIBERACION DE LA ENERGIA ALMACENADA; Y D) UN MEDIO DE SALIDA DEL DETONADOR DISPUESTO DENTRO DE LA CAJA EN RELACION CON EL MEDIO DE ALMACENAMIENTO PARA GENERAR UNA SENAL DE SALIDA A LA DESCARGA DEL MEDIO DE ALMACENAMIENTO
Patent PE-35796-A1 (PE)
Inventor: FARACI WILLIAM S
IPC: A61K31/4427
Filed: 1995-08-02
Abstract: This invention relates to novel, pharmaceutically active benzimidazole derivatives of formula (I), wherein the dotted line, X and R<1> through R<7>, R<11> and R<15> through R<17> are defined as in the specification. These compounds exhibit central dopaminergic activity and are useful in the treatment of CNS disorders.
Patent PL-286573-A1 (PL)
Title: Liquid waste-free method for manufacturing phosphate coatings on metal surfaces
IPC: C23C22/13
Filed: 1990-08-21
Abstract: In a process for the production of phosphate coatings on metal surfaces by means of aqueous zinc phosphate solutions containing iron(II) and nitrate ions, it is possible to work in the absence of waste water if the metal surfaces are brought into contact with an aqueous phosphating solution which contains 
 
  0.4 to 30 g/l of Zn, 
  4 to 30 g/l of P2O5, 
  5 to 50 g/l of NO3, 
  not more than 10 g/l of Fe(II) and 
  not more than 0.3 g/l of Fe(III), 
  in which the weight ratio 
  free P2O5 : total P2O5 is (0.04 to 0.50) : 1, 
  which is supplemented with Zn, NO3 and P2O5 in a weight ratio of 
  Zn : NO3 : P2O5 = (0.60 to 0.30) : (0.2 to 0.4) : 1 
 and in which the Fe(II) content is established only by oxidation with nitrate, nitrite formed therefrom, optionally together with oxygen-containing gas, H2O2 and/or nitrous gases. A rinsing bath cascade comprising at least two rinsing baths is located downstream of the phosphating bath, water which has a low salt content, preferably salt-free water, is fed into the last rinsing bath, viewed in the direction of workpiece flow, the water overflow is passed into the preceding rinsing bath in each case or into the phosphating bath, and water having a low salt content or salt-free water is removed from the phosphating bath at least in an amount such that the said phosphating bath can hold the phosphate-enriched rinsing water from the cascade.
Patent PL-299177-A1 (PL)
Title: Novel heterocyclic compounds, pharmaceutical agent, method of obtaining such novel heterocyclic compounds and initial compounds for obtaining them
Inventor: BOYD DONALD BRADFORD
IPC: A61K31/435
Filed: 1993-06-03
Abstract: This invention provides pharmaceutical heterocyclic derivatives of the formula <CHEM>  in which R3 are specified nitrogen-containing fused rings. They antagonize angiotensin II receptors in mammals.
Patent PL-310238-A1 (PL)
Title: Clamp for securing a hardware component and method of making such clamp
Inventor: RODER ERWIN
IPC: F16B37/04
Filed: 1995-08-31
Abstract: The clamp secures the fitting (1) to a window or door frame (2) at an undercut groove (4), the undercuts are formed by opposite transverse ribs (3,5). A clamping piece (6) bears against the underside of one of the ribs, and a mounting plate (7) is pressed against it, the piece hinging on the plate. A face (10) on the latter is pressed against the opposite side of the rib to the piece, and a face (11) at the free plate end bears against the frame. The piece bears only against the rib (3), and the mounting plate bears against the groove bottom between the ribs (3,5). The piece is mounted on the side of the plate. The face can be on a rib (9) protruding from the plate into the groove. The plate can bear via a distance-piece against the groove bottom, while the distance-piece can be joined to the clamping piece via a thin transverse wall containing an extension fold. A rounded portion on the clamping piece fits in a mating recess in the mounting plate to form a hinge.
Patent PL-310346-A1 (PL)
Title: Heterocyclic n-oxides substituted benzoyl guanidines, method of obtaining them and therapeutic agents containing such compounds
Inventor: KLEEMANN HEINZ-WERNER
IPC: C07D213/89
Filed: 1995-09-08
Abstract: Benzoyl guanidine derivs. of formula (I) and their salts are new: one of R1-R3 = Het (linked by C or N), SR10, OR10, NR10R11 or CR10R11R12; and the other two of R1-R3 = H, halo, CN, X(CH2)p(CqF2q+1), SOuR22, CONR23R24, COR25, SO2NR26R27, 1-8C alkyl, 2-8C alkenyl, CmH2mR14, OR35 or NR35R36; R4, R5 = H, 1-4C alkyl, Fl, Cl, OR32, NR33R34 or CrF2r+1; R10 = CnH2n-Het; Het = 1-9C heteroaryl-N-oxide (opt. substd. by 1-3 F, Cl, CF3, OMe, OH, NH2, NHMe or NMe2); R11, R12 = as R10, H or 1-4C alkyl; R14 = 3-9C cycloalkyl or phenyl (opt. by 1-3 F, Cl, CF3, Me, OMe, NH2, NHMe or NMe2); R11, R12 = as R10, H or 1-4C alkyl; R14 = 3-8C cycloalkyl or phenyl (opt. substd. by 1-3 F, Cl, CF3, Me, OMe, NH2, NHMe or NMe2); X = a bond, O, S or NR28; R22 = 1-8C alkyl, 2-6C alkenyl, CmH2mR29 or CF3; R23, R25, R26 = H or as R22; R24, R27 = H or 1-4C alkyl; or R23 + R24, R26 + R27 = (CH2)4 or (CH2)5 (both opt. with a CH2 replaced by O, S, NH, NMe or N-benzyl); R28 = H or 1-3C alkyl; R29 = 3-7C cycloalkyl or phenyl (opt. mono- or tri-substd. by F, Cl, CF3, Me, OMe or NR30R31; R30, R31 = H or 1-4C alkyl; R35, R36 = H or 1-6C alkyl; or R35 + R36 = (CH2)y (opt with a CH2 replaced by O, S, NH, NMe or N-benzyl); R32-R34 = H or 1-3C alkyl; n, p, u = 0-2; m = 0-4; r = 1-4; q = 0-6; y = 4-7. Also claimed are cpds. of formula (IIIA); A = Cl, OR45, OH, OM or imidazol-1-yl; M = alkali or alkaline earth metal ion; and R45 = 1-8C alkyl or 1-4C alkylphenyl.
Patent PL-311693-A1 (PL)
Title: Covering sheet metal strip
Inventor: HOFMANN KARL-HEINZ
IPC: E04D13/04
Filed: 1994-05-10
Abstract: A sheet metal covering strip (10; 110; 210; 310) is disclosed, in particular for buildings or the like. In order to create a sheet metal covering strip which is easy to produce, which may be easily bordered without tools in one or several predetermined, substantially linear areas and which is otherwise stiff and may be laid with an overlapping section on a similar sheet metal covering strip, so as to prolong it, the sheet metal covering strip (10; 110; 210; 310) consists in at least one preferably longitudinal narrow area (12; 112; 212; 312) of a material of less resistance and higher breaking elongation than the material in the adjacent areas (26, 28; 126, 128; 226, 228; 326, 328) of the sheet metal covering strip (10; 110; 210; 310). The narrow area(s) of the disclosed sheet metal covering strip may be made of another metal, another metal alloy or of the same metal but with a different structure than the remaining areas, or of a non-metallic material such as plastics. The material of the narrow areas may be joined in a water-tight manner to the material of the adjacent areas, for example by overlapping. Areas having different structures may be obtained by cold forming or by softening in a strip made of a uniform metallic raw material. The flexibility of the sheet metal varies from area to area. The narrow areas have less resistance and higher breaking elongation than the adjacent areas and constitute predetermined bending lines.
Patent PL-314985-A1 (PL)
Title: Bottle handling holder
Inventor: BAKX MARTINUS
IPC: B65D71/46
Filed: 1994-12-14
Abstract: A top gripping carrier (11) packaging necked articles such as bottles (B) comprises top (18, 28), side (20, 26) and bottom (22, 24) walls, neck receiving apertures (38) and article retaining means (60) disposed intermediate the bottom and top wall adapted to retain the top of the associated article (B) within the carrier obscured from view from above and from the sides of the carton.
Patent PL-324499-A1 (PL)
Title: Glass panel with an antireflexion coating
Inventor: BOIRE PHILIPPE
IPC: G02B1/115
Filed: 1997-05-14
Abstract: PCT No. PCT/FR97/00857 Sec. 371 Date May 14, 1998 Sec. 102(e) Date May 14, 1998 PCT Filed May 14, 1997 PCT Pub. No. WO97/43224 PCT Pub. Date Nov. 20, 1997The invention relates to a glazing pane having an "A" antireflection coating on at least one of its external faces, which antireflection coating comprises a stack of layers of materials having alternately high and low refractive indices. At least some of the layers of the said stack are pyrolysed layers, especially the final layer.
Patent PL-327832-A1 (PL)
Title: Method of measuring height of a cutting bench
Inventor: LANGKJAER CARSTEN
IPC: A01D41/14
Filed: 1997-01-29
Abstract: A method for measuring the height of the cutting table of an earth-processing implement or an agricultural implement, such as, for example, a combine harvester, relative to a surface of a ground having crops by means of an acoustic transducer arrangement. The method includes forming the sound signal emitted by the transducer arrangement by a pseudonoise signal covering a predetermined frequency band. Comparing the sound signal with the reflected signal. Mutually delaying the sound signal and the reflected signal until the comparison has reached its optimum. Whereafter, the delay represents a measurement of the distance to the surface of the ground.
Patent PL-340484-A1 (PL)
Title: Thrust disk for a grinding wheel
IPC: B24D9/08
Filed: 2000-06-02
Abstract: This invention provides an improved backup pad for an abrasive disk adapted to permit a view of surface as it is being ground which comprises a compressible pad (1) and a relatively rigid support member (4) laminated to the pad (1) that has shorter radial dimensions than the pad (1) in those portions of the circumference of the pad (1) that are likely to snag an angled surface during grinding. The result is that abrasive disks borne on the pad are less likely to tear from such contact.
Patent PL-340801-A1 (PL)
Title: Screw-type agitator for a mixing apparatus
Inventor: MELCHIOR MARTIN THEODOR
IPC: B28C5/42
Filed: 1998-12-09
Abstract: The invention relates to a twirling stick for a mixing device with two mixing sticks arranged at a distance in a substantially parallel position with respect to its rotational axis and a conveyor spiral arranged thereon, whereby said mixing stick is joined to a drive motor on one end and a feed pump on the other. The conveyor spiral is arranged in the vicinity of a conveyor funnel which is tapered towards the feed pump. The mixing device has a mixing area below the conveyor funnel into which a duct flows so that water can be introduced. The inventive twirling stick is designed in such a way that it the mixing process is made more efficient and lumps are avoided wherever possible. At least one semi-mixing stick (2a) is thus arranged in the orbit of the mixing sticks (2) between the mixing sticks. The angular distance of the semi-mixing stick to a mixing stick arranged in a prior position in the direction of rotation ranges from 45 DEG  to 135 DEG .
Patent PL-345347-A1 (PL)
Title: Rollers and method for the production thereof
Inventor: PICKELMANN GUENTER NORBERT
IPC: F16C13/00
Filed: 1999-07-16
Abstract: The invention relates to rollers comprised of a metal core having a coating made of an elastomeric material. Said rollers comprise a layer made of a synthetic material, namely polyurea, which is situated between the metal core and the elastomeric material. The exposed metal parts of the metal core are also preferably coated with polyurea.
Patent PL-349463-A1 (PL)
Title: Phenylalaninol derivatives
Inventor: SIDDURI ACHYTHARAO
IPC: C07C249/00
Filed: 2000-02-12
Abstract: New Phenylalaninol derivatives (I). Phenylalaninol derivatives of formula (I) are new: [Image] X : a benzamide group of formula (i), a heterocyclyl-amide group of formula (ii) or an imidazolin-3-yl-4-one group of formula (iii): [Image] R 15halo, NO 2, CN, lower alkylsulfonyl, lower alkyl, lower alkoxy, lower alkoxycarbonyl, carboxy, lower alkylaminosulfonyl, lower perfluoroalkyl, lower alkylthio, lower hydroxyalkyl, alkoxy-lower alkyl, alkylthio-lower alkyl, alkylsulfinyl-lower alkyl, alkylsulfonyl-lower alkyl, lower alkylsulfinyl, lower alkanoyl, aroyl, aryl or aryloxy; R 16H, halo, NO 2, CN, lower alkyl, OH lower perfluoroalkyl or lower alkylthio; Het : 5-6 membered heteroaryl containing 1-2 N, O or S; or 9-10 membered bicyclic heteroaryl containing 1-4 O, S or N; R 30H or lower alkyl; p : 0-1; R 18aryl or heteroaryl; R 19optionally substituted lower alkyl, aryl, heteroaryl, aralkyl or heteroaralkyl; R 20lower alkanoyl or aroyl; Y : a group of formula (iv) or (v) or a 5-6 membered heteroaryl, bonded via C and containing 1-3 O, N or S and optionally substituted by 1-2 lower alkyl, cycloalkyl, halo, CN, perfluoroalkyl or aryl, provided that at least one of the substituents is adjacent to the bonding C; [Image] a : an optional double bond; R 22, R 23H, lower alkyl, lower alkoxy, lower cycloalkyl, aryl aralkyl, NO 2, CN, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkanoyl, halo or perfluoro lower alkyl; provided that at least one is not H; R 24H, lower alkyl, lower alkoxy, aryl, NO 2, CN, lower alkylsulfony or halo; R 25lower alkyl, lower alkenyl (optionally fluorinated) or R 26(CH 2) e; R 26aryl, heteroaryl, N 3, CN, OH, lower alkoxy. lower alkoxycarbonyl, lower alkanoyl, lower alkylthio, lower alkylsulfonyl, lower alkylsulfinyl, perfluoro-lower alkanoyl, NO 2 or NR 28R 29; R 28H or lower alkyl; R 29H, lower alkyl, lower alkoxycarbonyl, lower alkanoyl, aroyl, perfluoro lower alkanoylamino, lower alkylsulfonyl, lower alkylaminocarbonyl or arylaminocarbonyl; or R 28 + R 294-6 membered carbocyclic ring optionally containing 1 O, N or S and optionally substituted on C by lower alkyl or halo; Q : (CH 2) fO, (CH 2) fS, (CH 2) fN(R 27), (CH 2) f or a bond; R 27H, lower alkyl, aryl, lower alkanoyl, aroyl or lower alkoxycarbonyl; e : 0-4; and f : 1-3. An independent claim is included for preparation of (I). ACTIVITY : Antirheumatic; antiarthritic; antiasthmatic; antiinflammatory; neuroprotective. MECHANISM OF ACTION : (I) inhibit the binding of vascular cell adhesion molecule-1 (VCAM1) and fibronectin to the integrin VLA-4 (not defined) on circulating lymphocytes, eosinophils, basophils and monocytes.
Patent PL-355629-A1 (PL)
Title: Method for producing cut sections consisting of composite materials
Inventor: RAU FRIEDRICH
IPC: B26D7/01
Filed: 2000-11-24
Abstract: The invention relates to a method for producing cut sections consisting of composite materials, according to which sections are cut out of a layer of material. Several layers of composite materials, each comprising at least one cover layer (4) which has a pattern and a foam layer (5) are arranged one on top of the other to form a stack (10) with their patterns matched on a needle table (20) in such a way that the motif of the cover layers (4) of the individual layers are in exact alignment with each other. The stack (10) is fixed, in order to maintain the exact pattern alignment of the individual composite layers and is placed on the working plate (31) of a cutting installation (30). The stack (10) is compressed by the generation of a vacuum, whereby the foam layers (5) of the individual composite layers are compressed. The individual cut sections are then cut out of the compressed stack (10).