baber/WOPTO huggingface dataset:
Patent CN-1682266-A (CN)
Inventor: ROSMALEN GERARD E
IPC: G09G3/32
Filed: 2003-08-08
Abstract: 本发明涉及一种具有多个像素(110)的有源矩阵显示装置(10)。这些像素分成像素组(R′，G′，B′)。为每个像素组(R′，G′，B′)指定特定占空度，使得至少两个像素组被指定不同占空度。该装置还包括用于以其指定占空度驱动每个像素组(R′，G′，B′)的电路(54)。本发明还涉及这种显示装置的驱动。
Patent CN-1694878-A (CN)
Inventor: NICHOLAS HOUSON IAN
IPC: C07D333/24
Filed: 2003-09-12
Abstract: 提供了一种制备式(1)化合物的方法：式(1)中：X为S、O或NR 3 ，其中R 3 为H或有机基团；R为H或有机基团；R 1 和R 2 各自独立为H、任选取代的烷基或任选取代的芳基；G为取代基；且n为0－3：所述方法包括以下步骤：(a)式(2)化合物与式NHR 1 R 2 的化合物反应得到式(3)化合物：式(2)、式(3)中X、R、G和n如上定义且R 4 为任选取代的烷基、任选取代的烯基、任选取代的炔基、任选取代的芳基、任选取代的杂芳基或它们的组合；和(b)还原式(3)化合物得到式(1)化合物。也提供了制备式(2)化合物、新的式(3)化合物及一些优选的式即式(A)的催化剂的方法，式(A)中：R 6 代表中性的任选取代的烃基、中性的任选取代的全卤代烃基或任选取代的环戊二烯基配体；A代表任选取代的氮；B代表任选取代的氮、氧、硫或磷；E代表连接基团；M代表能催化转移氢化的金属；且Y代表阴离子基团、碱性配体或空位；条件是A或B中至少一个包含取代的氮且取代基具有至少一个手性中心；且条件是当Y不为空位时，A或B中至少一个带有氢原子。
Patent CN-1771289-A (CN)
Title: 树脂基内部装饰材料
Inventor: TOSHIAKI INADA
IPC: E04F19/04
Filed: 2003-05-16
Abstract: 一种树脂基内部装饰材料，该材料包括10－45质量份乙烯－乙酸乙烯酯共聚物、10－90质量份聚烯烃树脂、10－90质量份苯乙烯和脂族不饱和烃的嵌段共聚物或该共聚物的氢化产物(苯乙烯/(聚)烯烃嵌段共聚物)和100－700质量份无机填料。此内部装饰材料不包含卤素和增塑剂如邻苯二甲酸酯，可以代替PVC树脂基内部装饰材料，并展示出对通常用于内部装饰材料的粘合剂和蜡的优异粘附性以及显著优于其它非卤素树脂基内部装饰材料的加工性能、适用性和耐用性。当乙烯－乙酸乙烯酯共聚物的MFR比其它树脂的MFR高至少20g/10min并且苯乙烯－(聚)烯烃嵌段共聚物的玻璃化转变温度(Tg或tanδ峰温度)在常温附近时，内部材料在对基材外形的适应性、耐划痕性和耐磨性方面是特别优异的。
Patent CN-1031044-A (CN)
Inventor: XUECHENG DING
IPC: H01B3/00
Filed: 1988-06-20
Abstract: 本发明涉及一种高压电气绝缘材料。对基材玻
璃布采用电加热，改进了浸胶配方，完善了固化工艺，
提高了机械、物理性能，消除了定向及不定向翘曲；更
采用多力点层压机进行脱腊热处理，在加热浸胶过程
中由于压力均匀，成型的耐高湿度环氧酚醛玻璃布板
质地细密、粘合力强、不吸水、不炭化、可用无齿锯切
割。
Patent CN-1040624-A (CN)
Title: 枳椇果梗糖浆生产工艺
Inventor: JINGLUN YI
IPC: C13B20/00
Filed: 1988-09-01
Abstract: 一种以枳椇果梗为原料，经过压榨取汁，防腐澄清、脱色过滤、脱涩浓缩，制备一种新型食用糖—枳椇糖浆的生产工艺。其方法简单，生产投资少，经济效益显著，制成的糖浆总固物大于80％，其中总糖为70～75％，富含锌、钙等人体必须的营养元素和其它营养成份，并具独特风味，可以直接作为营养品和食糖食用，也可作食品医药工业的食糖原料，本生产尤适宜于广大农村乡镇企业生产。
Patent CN-1062850-A (CN)
Inventor: CHANGXUE REN
IPC: A61N5/02
Filed: 1990-12-29
Abstract: 本发明是有关一种人体微波透热法及装置，它是

根据微波功率密度衰减的规律，在现有贴近式透热法

的基础上，将微波辐射器2的口面离开人体被透热部

位体表15～70cm的距离，在微波辐射器2口面前加

一聚焦装置3，并加大微波电源1的输出功率，微波

电源1的输出功率可自动调节，且连续最大功率输出

大于1.2kW。该方法与装置能较好地解决透热深度

浅、表皮易灼伤、加热不均匀等问题，适用于人体与动

物的某些疾病治疗，特别适用于人体深部癌的治疗。
Patent CN-1056481-A (CN)
Title: 人造玉石
Inventor: JIEREN YU
IPC: C04B35/18
Filed: 1991-03-05
Abstract: 本发明是一种人造玉石和其制作方法。本发明
将海砂、石灰、长石粉等原料，通过二个以上不同温度
的炼料炉高温烧成并在同一作业部混合，使其产生不
同的颜色层次和不混溶界面，然后送入铜模压制成
型，再退火析出并成长为晶体，冷却后打磨抛光成产
品。本发明具有一次成型、减小能耗、降低成本等优
点。
Patent CN-1091123-A (CN)
Inventor: HANSHENG XU
IPC: A01N37/44
Filed: 1993-02-18
Abstract: 一种合成的新植物生长调节剂：N，N-二乙胺基
乙基-4-氯-α-异丙基苄基羧酸酯盐酸盐。该产物
的合成方法是用计算量的2-(4′-氯苯基)-3-甲基
丁酰氯与N，N-二乙胺基乙醇在无水苯中，40℃反
应6.5小时得到的酯，纯化后在无水苯中通入干燥氯
化氢即得，产品为白色晶体，M.P157～158℃。初步
大田试验对油菜增产23.96％，对小麦增产
17.45％。统计分析农业增产效果达极显著水平。
Patent CN-1235353-A (CN)
Inventor: TSUCHIYA TOMOHIRO
IPC: G11C29/00
Filed: 1999-03-04
Abstract: 一种半导体器件,包括具有标准单元阵列和冗余单元阵列的块。R/N转接设置电路包括串联的多个晶体管。冗余确定电路接收一个地址,并确定是否采用冗余单元阵列。若采用冗余确定电路不仅输出有效YPR信号,而且输出故障单元阵列的目前列方向位置。该位置信息通过冗余位置译码器提供给转接设置电路。转接设置电路产生转接信号DSW,并输出给R/N转接电路。转接电路将输入/输出部分的I/O线转接到所选标准单元阵列和冗余单元阵列。
Patent CN-1302657-A (CN)
Title: 诱导分化治疗的药物及其应用
Inventor: CHENG XIAODONG
IPC: A61P7/00
Filed: 1999-10-29
Abstract: 一种黄芪等诱导分化治疗的药物,通过诱导肿瘤细胞中β－珠蛋白基因从不表达到表达,促进β－globinmRNA翻译成珠蛋白和合成血红蛋白,诱导肿瘤细胞趋向终末分化,成为正常或接近正常的细胞,从而达到抗肿瘤的目的。本发明药物显著优于目前国际上公认的诱导分化药物羟基脲,而且无毒副作用。可用于治疗造血系统肿瘤、β－地中海贫血及镰刀性贫血等疾病,展示了广阔的应用前景。
Patent CN-1257005-A (CN)
Title: 印刷机的调温设备
Inventor: RAGE JURGEN
IPC: B41F7/37
Filed: 1999-12-09
Abstract: 印刷机的调温设备,包括一个调温回路(2),调温回路有一根在回路内所含泵(4)吸入侧(20)的流体输入导管(16、18)以及一根同样在泵(4)吸入侧的流体返回导管(22)。这两根导管(16、22)连接在调温流体源(10)上。在这两根导管(16、22)在调温流体回路(2)上的连接点(18、24)之间的调温回路中有一流动阻尼器(32)。
Patent CR-20140489-A (CR)
Title: Uso de 18-metil-15b, 16b-metilen-19-nor-20-espirox-4-en-3-onas en el tratamiento de menorragia, y sistemas intrauterinos que comprenden 18-metil-15b, 16b-metilen-19-nor-20-espirox-4-en-3-onas para el tratamiento de t
Inventor: SCHMEES NORBERT
IPC: A61P15/00
Filed: 2014-10-23
Abstract: Uso intrauterino de 18-metil-15fÀ,16fÀ-metilen-19-nor-20-espirox-4-en-3-onas de formula general (1)
Patent CR-20150422-A (CR)
Title: Formas de metilo {4,6-diamino-2-[1- (2-fluorobencil) -1h-pirazolo [3,4-b] piridino -3-il] pirimidino-5-il} carbamato de metilo
Inventor: KEIL BIRGIT
IPC: C07D471/04
Filed: 2015-08-18
Abstract: Esta presente invención se refiere a las formas del metil {4,6-diamino-2-[1-(2-fluorobencil)-1H-pirazolo[3,4-b]piridino-3-il]pirimidino-5-il}metilcarbamato que comprende su modificación I. modificación II. solvato de mono-DMSO. solvato de sesqui-DMSO y solvato de 1/4-acetato de etilo.
Patent CR-20170448-A (CR)
Title: Método e instalación de transferencia de contenedores para colocar contenedores en y remover contenedores de áreas de almacenamiento de contenedores
Inventor: BANNERT MICHÉL
IPC: B66C19/00
Filed: 2015-04-14
Abstract: La invención se relaciona con un método y una instalación de transferencia de contenedores (2, 102) para colocar contenedores hacia y remover contenedores desde o transferir 5 contenedores (1) en área de almacenamiento en bloque o estante vertical (3, 15) de un puerto marítimo o un puerto terrestre dentro de una instalación de transferencia de contenedores (2, 102) que tiene un sistema de transporte de contenedores totalmente automático integrado. Un proceso 10 acelerado que tiene alto rendimiento total se consigue en tales contenedores individuales (1) depositados por al menos una grúa de carga (6) sucesivamente en tarimas (19) o carritos de transporte transversal (18) proporcionados en un carrito de transporte (8; 8a, 8b) que al menos tiene un nivel 15 de alojamiento y transporte superior e inferior (I, II) y se puede mover paralelo al área de almacenamiento de contenedores (3,15) y las tarimas (19) cargadas con un contenedor (1) se conducen por medio de medios de transporte transversal de tarima (25) o los contenedores (1) se conducen 20 por medio de carritos de transporte transversal (18) del carrito de transferencia (8; 8a, 8b) desde el carrito de transferencia hasta un vehículo de distribución final (9; 9a y 9b), que puede moverse paralelo al área de almacenamiento de contenedores (3,15) y se coloca en línea
Patent CR-20170606-A (CR)
Title: Depurador de gas multiniveles con multiples cabezales de depuración inundados
Inventor: MCCLELLAND KENNETH JAMES
IPC: B01D47/02
Filed: 2015-11-02
Abstract: La presente invención se refiere a un diseño de cabezal en húmedo cuya orientación horizontal y características de funcionamiento inundado permiten una depuración en húmedo completa en múltiples zonas de interacción, cada una con diferentes reactivos neutralizantes.
Patent CR-20200325-A (CR)
Title: Bispecific antibody construct directed to muc17 and cd3
Inventor: RAUM TOBIAS
IPC: C07K16/46
Filed: 2018-12-31
Abstract: <p>The present invention provides bispecific antibody constructs characterized by comprising a first domain binding to MUC17, a second domain binding to an extracellular epitope of the human and the <em>Macaca</em> CD3ε chain and optionally a third domain, which is a specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.</p>
Patent CR-20210234-A (CR)
Title: Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
Inventor: WEINSCHENK TONI
IPC: G01N33/68
Filed: 2016-03-17
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Patent EC-SP003819-A (EC)
Title: COMPUESTOS DE PIRROLO (2,3-d) PIRIMIDINA
Inventor: MUNCHHOF MICHAEL JOHN
IPC: A61K31/519
Filed: 2000-12-08
Abstract: Compuestos de la fórmula en la que R1, R2 y R3 son como se definieron anteriormente, que son inhibidores de enzimas deproteína quinasas tales como Janus Quinasa 3 y que, como tales son, agentes terapéuticos útiles como agentes inmunosupresores para transplantes de órganos, xenotransplante, lupus, esclerosis múltiple, artritis reumatoide, soriasis, diabetes de tipo I y complicaciones debidas a la diabete, cáncer, asma, dermatitis atópica, transtornos tiroideos autoinmunes, colitis ulcerosas, enfermedades de Crohn, enfermedad de Alzheimer, leucemia y otras enfermedades autoinmunes.
Patent EC-SP034806-A (EC)
Title: Un producto absorbente con ajuste mejorado
Inventor: DREVIK SOLGUN
IPC: A61F13/00
Filed: 2003-10-16
Abstract: Un producto absorbente, tal como una toalla sanitaria, con un elemento rigidizante (6) que está diseñado para contribuir a la forma tridimensional del producto durante su uso. El elemento rigidizante (6) se encuentra en estado plano antes del uso del producto y tiene una rigidez en un estado seco de alrededor de 1 - 15 N, medida de conformidad con el método ASTM D 4032-82. El elemento rigidizante tiene una anchura de alrededor de 15-45 mm en el área de transición entre la porción de la entrepierna (3) y la porción frontal (1) en la toalla sanitaria, la misma que se adapta a la distancia entre los tendones musculares del usuario a ambos lados de la entrepierna del usuario en la ingle de este último. El producto tiene rigidez diferente a lo largo de una línea central que se extiende en la dirección longitudinal del mismo, como resultado de lo cual el producto está predestinado a encorvarse en lugares predeterminados a lo largo de dicha línea central cuando el producto está predestinado a encorvarse en lugares predeterminados a lo largo de dicha línea central cuando el producto se fija en el usuario.
Patent EC-SP045506-A (EC)
Title: Mezclas fungicidas a base de dithianon
Inventor: AMMERMANN EBERHARD
IPC: A01N43/32
Filed: 2004-12-22
Abstract: Mezclas fungicidas, que contienenA)	el compuesto de la fórmula IyB)	un derivado de pirimidina de la fórmula II,en la que R significa metilo, ciclopropilo ó 1-propinilo, en una cantidad sinergética activa, procedimientos para controlar hongos nocivos con mezclas de los compuestos I y II y el uso de los compuestos I y II para la obtención de tales mezclas.
Patent EC-SP055652-A (EC)
Title: Un nuevo proceso para la preparación de derivados de epotilona, nuevos derivados de epotilona, así como nuevos productos intermediarios para el proceso, y los métodos para su preparación
Inventor: LOISELEUR OLIVIER
IPC: C07D303/18
Filed: 2005-03-09
Abstract: La presente invención proporciona una síntesis para la preparación de derivados de epotilona de la fórmula 9, en donde:		R1 es metilo, y		R2 tiene el significado de un arilo insustituido o sustituido, un heteroarilo insustituido o sustituido, o un radical heterocíclico insustituido o sustituido fusionado con un núcleo de benceno,		y sales de los mismos,		e intermediarios para la síntesis de un compuesto de la fórmula 9.
Patent EC-SP077628-A (EC)
Title: Nueva composición farmacéutica
Inventor: MULLER FRANCIS X
IPC: A61K31/337
Filed: 2007-07-27
Abstract: Se describen nuevas composiciones farmacéuticas que contienen bis-(monoetanolamina) del ácido 3'-[(2Z)-[1-(3,4-dimetilfenil)-1,5-dihidro-3-metil-5-oxo-4H-pirazol-4-ilideno]hidrazino]-2'-hidroxi-[1,1'-bifenil]-3-carboxílico (eltrombopag olamina) y procesos para su preparación.
Patent EC-SP099317-A (EC)
Title: Reducción de fricción de crudos asfalténicos
Inventor: HARRIS WILLIAM F
IPC: C10M141/00
Filed: 2009-05-04
Abstract: Un sistema para la reducción del descenso de presión asociado con un flujo turbulento de crudos asfalténicos a través de un conducto. El crudo tiene un alto contenido de asfalteno y/o una gravedad API baja. Dicha reducción en el descenso de presión es alcanzada tratando el crudo asfalténico con un polímero reductor de fricción de lato peso molecular que puede tener un parámetro de solubilidad dentro de aproximadamente 20 por ciento del parámetro de solubilidad del crudo pesado. El polímero reductor de fricción también puede comprender los residuos de monómeros que tienen al menos un heteroátomo.
Patent EC-SP993073-A (EC)
Title: Composicion termoplastica biodegradable con humectabilidad mejorada
Inventor: TSAI FU-JYA DANIEL
IPC: C08F291/08
Filed: 1999-07-28
Abstract: Una composición termoplástica que comprende una mezcla no reaccionada de un polímero de poliester alifático seleccionado del grupo que consiste de polímero de succinato de polibutileno, un polímero de succinato-co-adipato de polibutileno, un polimero de policaprolactona, una mezcla de tales polímeros, o un copolímero de tales polímeros; un ácido multicarboxilico; y un agente humecedor. La composición termoplástica es capaz de ser extruida en fibras que pueden formarse en estructuras no tejidas que pueden ser usadas en un producto absorbente desechable intentando par la absorción de fluiodos tales como los fluiods del cuerpo.
Patent FR-1568622-A (FR)
IPC: G01R11/12
Filed: 1968-06-12
Granted: 1969-05-23
Abstract: 1,206,372. Bearings. SIEMENS A.G. 17 May, 1968 [16 June, 1967; 16 Nov., 1967], No. 23727/68. Heading F2A. A footstep ball bearing has a ball 2 disposed between two bearing bushes, one of which, 3, has a concave bearing surface having a radius of curvature greater than that of the ball, and the other 44 having a pyramidal bearing surface. The bushes are of plastics material, and the pyramidal surface is triangular.
Patent FR-1602968-A (FR)
Title: Autoclave door
IPC: F16J13/24
Filed: 1968-08-30
Granted: 1971-03-01
Abstract: Autoclave door moves out of the way in a plane perpendicular to the autoclave axis. The plane of closure proper forms a small angle with this plane of movement. The door has an angular shape to ensure sealing. Pref. the door is locked automatically by a ram actuated by the autoclave pressure.
Patent GB-1000693-A (GB)
Abstract: 1,000,693. Rails with sound-insulating packing. MANNESMANN-LEICHTBAU G.m.b.H. Aug. 10, 1962 [Aug. 14, 1961], No. 30729/62. Heading E1G. A rail 1 for the travelling carriages of suspended cradles or the like is welded to bearing plates 2 which are bolted to inverted channel section sleepers 3. The sleeper is welded to base plates 4 which rest on sound-absorbing plates 5 of lead asbestos. Bolts 7 associated with washers 9 of lead asbestos pass through with play elongated holes 6 in the plates 4.
Patent GB-1050195-A (GB)
IPC: G03B21/43
Abstract: 1,050,195. Cine projectors. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. March 11, 1964 [March 14, 1963], No.10286/64. Heading G2E. In a cine projector the two film reels 6 are supported one on each side of the projector casing 8 upon spindles 7, rollers 2 being provided to lead the film 3 in a single loop above the projector by way of sprockets 1. For re-winding, the film is removed from the gate and rollers 2 and is led in front of the projection lenses 18 and over further rollers above the projector to the supply spool. A resiliently mounted roller bears on the film for re-winding. Each spindle has a spring clip to retain the reel, and a driving disc with a reel engaging stud.
Patent GB-1050736-A (GB)
IPC: A61K31/00
Abstract: 1,050,736. Indole derivatives. MERCK & CO. Inc. Jan. 29, 1964 [Feb. 1, 1963], No. 2067/66. Divided out of 1,050,728. Heading C2C. Indole-3-acetic acid derivatives of the formula wherein R 1  is an aryl, heterocyclic aryl or substituted aryl or, heterocyclic aryl radical; R 2  is at hydrogen atom or a C 1-5  alkyl, . C 2-5  alkenyl, aryl, aralkyl, alkaryl substituted alkyl or substituted aryl radical, R 3  is hydrogen or a C 1-5  alkyl or C 2-5  alkenyl radical and R 5  is a hydrogen or halogen atom or a C 1-5  alkyl, C 1-5  alkoxy, haloalkyl, nitro, amino, substituted amino, cyano, aminomethyl, mercapto dialkyl sulphamoyl or benzylmercapto radical are made from the appropriate 1-acyl-2-R 2 -5-R 5 -indoxyl I by (a) heating with an α-halo-t.-butyl ester R 3 CHX.COO.C(CH 3 ) 3  and a catalytic amount of zinc in an inert solvent and heating the resulting t.-butyl ester of a 1-acyl-2-R 2 -5-R 5 -3-hydroxyindoline-3-acetic acid II, with a strong acid, e.g. p-toluenesulphonic acid; (b) heating with a triphenyl phosphine (C 6 H 5 ) 3 P = CR 3 .COOC(CH 3 ) 3  to give II and heating with a strong acid, or (c) heating with a malonic acid R 3 CH.(COOH) 2  in the presence of an organic base and heating the resulting product (the free acid of II. with a strong acid while-removing water azeotropically. Acyl-indoxyls I used as starting materials are made by reacting a 5-R 2 -anthranilic acid, e.g. 5-methoxy-anthranilic acid, with an α-halo-2- R 2 -acetic acid, e.g. α-chloropropionic acid, to produce an N-o-carboxyphenyl-glycine, e.g. N-(2- carboxy - 4 - methoxyphenyl) - alanine, treating with a halide of the acid R 1 COOH, such as p chlorobenzoyl chloride, to give the corresponding N-acyl-N-phenyl-glycine and condensing with acetic anhydride and acetic acid to give a 1 - aryl - 2 - R 2  - 5 - R 5  - 3 - acetoxyindole, which is then refluxed with a solution of a sulphite or bisulphite. t - Butyl triphenylphosphonium - acetate (C 6 H 5 ) 3 P = CH.COO.C(CH 3 ) 3  is made by reacting triphenylphosphine with t.-butyl bromoacetate.
Patent GB-1051552-A (GB)
IPC: B05B11/00
Abstract: 1,051,552. Reciprocating pumps. VALVE CORPORATION OF AMERICA. March 9, 1964 [May 8, 1963], No.9935/64. Heading F1A. In a pump mounted on a liquid container, the pump piston 54 has an actuator stem 22 passing out of the cylinder 34 and the stem 22 has a bore 62 for the discharge of liquid. The piston 54 comprises two elements 64, 66 and has a bore in which is located the stem 76 of a valve member 78. When the actuator button 14 is depressed, liquid in the cylinder 34 is forced out through the bore 62 and orifice 16 while air enters the container through the clearance between the stem 22 and opening 24 and an opening 56 which is uncovered by the piston element 66. The valve stem 76 rests on a shoulder 84 and being spring loaded remains fixed during pumping. The lower end of the stem 76 is D-shaped to allow liquid to enter the chamber during the piston suction stroke.
Patent GB-1051862-A (GB)
IPC: G03B7/083
Abstract: 1,051,862. Photographic cameras. INTERNATIONAL POLAROID CORPORATION. March 26, 1964 [March 29, 1963 (2)], No. 12869/64. Heading G2A. [Also in Division G1] In a photographic camera exposure control of the type in which a photoresistor forms part of a capacitor charging circuit, the exposure being terminated when the capacitor voltage reaches a predetermined level photoresistor inertia to varying light intensity is compensated by a shutter varying the amount of light reaching the cell and/or a switch shorting a fixed resistor in the charging circuit. The shutter is initially cocked by actuating a lever 42, Fig. 1, whereby an arm 46 engages a rod 26 fixed to shutter vane 16 to push both vanes 14, 16 to the left until a pin 22 engages a latch 20. A keeper 36 on vane 14 completes the magnetic circuit of an electromagnet 34. Operation of the release key 30 first closes a switch S 1  which applies voltage to the exposure control circuit. Transistor 70 conducts to energize the solenoid 50 of magnet 34, so that vane 14 is retained when further movement of key 30 releases latch 20. Movement of shutter vane 16 to initiate exposure removes a short S 2  from  capacitor 52 which charges through a photoresistor 54 until the voltage at 60 is enough to operate a Schmitt trigger 62, 70. Current is cut off from solenoid 50, releasing vane 14 to terminate the exposure. The apparatus is calibrated for constant illumination with apertures 128 in front of photoresistor 54 and switch S 3  closed. The plug 116, Fig. 6, of photoflash apparatus which connects with jack 156 for flash synchronisation also carries a metallic arm 152 which engages a crank 132 to replace apertures 128 by the aperture 130 and an insulating arm 152, Fig. 7, which opens the contacts 162, 164 of S 3 . The ratio of the areas of apertures 128 and 130 and the valve of resistor 78 are chosen to compensate for the inertia of the photoresistor to the rapidly changing intensity of the photoflash.
Patent GB-1052653-A (GB)
IPC: C07D337/14
Abstract: 1,052,653. Dibenzothiepins. J. R. GEIGY A.G. April 30, 1964 [May 4, 1963], No. 17910/64. Heading C2C. The invention comprises compounds of the formula wherein X and Y independently of each other represent hydrogen, chlorine or bromine atoms or methyl or methoxy radicals, R 1  represents a hydrogen atom or a methyl radical, R 2  and R 3  represent hydrogen atoms or C 1-4  alkyl radicals, or R 2  and R 3  together with the adjacent nitrogen atom and with the optional inclusion of an oxygen atom, an imino group, a C 1-6  alkylimino group, a C 1-4  hydroxyalkylimino group or an alkanoyl oxyalkylimino group having at most 10 carbon atoms as ring members, represent a saturated heterocyclic ring with 5 to 7 ring members; acid addition salts thereof; and a process for their preparation comprising reacting reactive ester, e.g. a halide or sulphonic acid ester, of a hydroxy compound of the formula with a compound of the formula or with a metal compound of an N-acyl derivative of a C 1-4  alkylamine, if necessary hydrolysing the reaction product to split off any acyl radical which may be bound to an N-atom of the side chain, if desired treating a compound of the Formula I containing an imino group as ring member with an alkylene oxide having at most 4 carbon atoms, a reactive mono-ester of an alkane diol having at most 4 carbon atoms or with a reactive ester of an alkanoyloxy alkanol having at most 10 carbon atoms, if desired acylating a compound of the Formula I containing a C 1-4  hydroxyalkyl imino group as ring member into one containing an alkanoyloxylalkylimino group having at most 10 carbon atoms and, if desired, converting a compound of the Formula I into a salt with an inorganic or organic acid. Bromide esters of compounds of Formula II are prepared by -methylating or ethylating in the 11-position, e.g. by means of methyl or ethyl iodide, an appropriate dibenzo[b,f]- thiepin-10( 11H) -one to form the corresponding 11 - methyl or - ethyl - dibenzo[b,f]thiepin- 10 ( 11H) - ones, reducing these compounds, e.g. by means of LiAlH 4 , form the corresponding 11- methyl or - ethyl - 10,11 - dihydro - dibenzo [b,f]thiepin - 10 - ols, chlorinating these compounds, e.g. by means of SOCl 2 , to form the corresponding 10-chloro-11-methyl- or -ethyl- 10,11 dihydro - dibenzo[b,f]thiepins, splitting off hydrogen chloride from these compounds, e.g. by means of potassium tertiary butylate, to form the corresponding 10-methyl or -ethyldibenzo[o,f]thiepins and brominating the alkyl radical in the 10-position of these compounds, e.g. by means of N-bromosuccinimide. Pharmaceutical compositions having adrenolytic and central depressant activity, for oral or parenteral administration, comprise a compound of the invention together with a pharmaceutical carrier.