baber/WOPTO huggingface dataset:
Patent BR-PI1015727-B1 (BR)
Title: compostos fenil-pirazóis ftalimídicos bioativos, processo para preparação dos compostos, seu uso e composições farmacêuticas
Inventor: ANA LUISA PALHARES DE MIRANDA
IPC: A61K31/4035
Filed: 2010-09-08
Abstract: COMPOSTOS FENIL-PIRAZÓIS FTALIMÍDICOS BIOATIVOS, PROCESSO PARA PREPARAÇÃO DOS COMPOSTOS, SEU USO E COMPOSIÇÕES FARMACÊUTICAS. A inovação ora proposta diz respeito a novos compostos fenil pirazóis ftalimídicos capazes de atuarem como antinflamatório e analgésico. A presente invenção se refere também a composições farmacêuticas contendo tais compostos e seu uso no tratamento e modulação de condições e doenças mediadas por TNF-.
Patent BR-PI1106657-B1 (BR)
Title: refrigerador
Inventor: MYUNGRYUL LEE
IPC: F25D11/00
Filed: 2011-10-28
Abstract: REFRIGERADOR. A presente invenção se refere aos refrigeradores e mais particularmente ao refrigerador em que um espaço de vácuo é formado entre um compartimento exterior e um compartimento interior de um corpo do mesmo para reforçar a função de isolamento térmico. O refrigerador inclui um corpo com um espaço de armazenamento para armazenar um pré-determinado objeto de armazenamento, em que um corpo inclui um compartimento interior com um espaço de armazenamento, um compartimento exterior com uma superfície interna espaçada com uma lacuna pré-determinada a partir de uma superfície interna do compartimento interior para alojar o compartimento interior, um espaço de vácuo fornecido entre o compartimento interior e o compartimento exterior fechado para manter um estado de vácuo para isolamento térmico entre o compartimento interior e o compartimento exterior, e uma unidade de vedação para vedar uma frente do espaço de vácuo formado entre uma frente do compartimento interior e uma frente do compartimento exterior e reduzindo uma taxa de transferência de calor entre o compartimento interior e o compartimento exterior.
Patent EA-000121-B1 (EA)
Title: New staphylokinase derivatives
Inventor: COLLEN DESIRE
IPC: C12N9/52
Filed: 1996-01-03
Abstract: A method for producing the derivatives of the invention by preparing a DNA fragment comprising at least the part of the coding sequence of staphylokinase that provides for its biological activity; performing in vitro site-directed mutagenesis on the DNA fragment to replace one or more codons for wild-type amino acids by a codon for another amino acid; cloning the mutated DNA fragment in a suitable vector; transforming or transfecting a suitable host cell with the vector; and culturing the host cell under conditions suitable for expressing the DNA fragment. Preferably the DNA fragment is a 453 bp <u>Eco</u>RI-<u>Hin</u>dIII fragment of the plasmid <u>pMEX602SakB</u>, the in vitro site-directed mutagenesis is performed by an oligonucleotide-directed mutagenesis system using the plasmid <u>pMa/c</u> and the repair deficient E. coli strain WK6MutS, and the mutated DNA fragment is expressed E. coli strain WK6. The invention also relates to pharmaceutical compositions comprising at least one of the staphylokinase derivatives according to the invention together with a suitable excipient, for treatment of arterial thrombosis.
Patent EA-007469-B1 (EA)
Title: Cripto blocking antibodies and uses thereof
Inventor: SANICOLA-NADEL MICHELE
IPC: C12N5/09
Filed: 2002-04-17
Abstract: The invention provides Cripto blocking antibodies, or biologically functional fragments thereof, and uses thereof. Antibodies which bind Cripto and modulate Cripto signaling are provided. Antibodies which bind Cripto and block the interaction between Cripto and ALK4 are provided. Antibodies which bind Cripto and modulate tumor growth are also provided. Antibodies which bind Cripto, modulate signaling, and modulate tumor growth are also provided. Antibodies which bind Cripto, block the interaction between Cripto and ALK4 and modulate tumor growth are provided. The invention also provides methods of using these antibodies in therapeutic, diagnostic, and research applications.
Patent EA-009013-B1 (EA)
Title: Comprehensive front end method and system for automatically generating and processing photomask orders
Inventor: SUTILE EDWARD J
IPC: G03F9/00
Filed: 2005-06-01
Abstract: The present invention relates to a comprehensive front-end method and system for automatically generating and processing photomask orders. This method and system includes two separate, but related software components. The first software component of the present invention is used to generate a photomask order in a specified format. The second software component of the present invention processes at least a portion of the photomask order (which was generated using the first software component) into a substantially ready-to-write jobdeck file and/or a substantially ready-to-write inspection file, which in turn is transferred to a remote photomask manufacturer's system to manufacture a photomask. These software components can be installed as separate programs on a computer system or operate as a single software package performing multiple functions.
Patent EA-011289-B1 (EA)
Title: Composite tube
Inventor: HERNBLOM JOHAN
IPC: C10G9/14
Filed: 2004-08-27
Abstract: A composite tube having a corrosion resistant member and a load-bearing member is provided. The corrosion resistant member is a Cu-Al alloy and has a wall thickness of at least 0.5 mm, while the load-bearing member is a Fe, Ni or Co based alloy having a wall thickness of at least 1 mm. The composite tube can be manufactured by conventional means like extrusion, rolling, welding etc. The composite tube is to be used in environments where the risk of metal dusting, coking or carburisation is high.
Patent EA-012415-B1 (EA)
Title: Infusion and injection solution of levodopa
Inventor: DIZDAR SEGRELL NIL
IPC: A61K/
Filed: 2005-07-08
Abstract: An infusion or injection solution of Levodopa is disclosed containing at least 10 mg/mL of Levodopa, or at least 5 mg/mL of Levodopa together with at least 0.5 mg/mL of at least one inhibitor of a Levodopa-metabolising enzyme selected from the group consisting of dopa decarboxylase (DDC) inhibitors, catechol-o-methyltransferase (COMT) inhibitors, and monoamino oxidase (MAO-B) inhibitors, the solution further contains a buffer, a physiologically acceptable sugar, a physiologically acceptable acid and has a pH of lower than or equal to 6. There are also described a disposable syringe and an infusion pumpcassette containing a therapeutically effective amount of the infusion or injection solution of Levodopa.
Patent EA-011637-B1 (EA)
Title: Treatment with pmega-3 fatty acids and ppar agonist and/or antagonist and a combination product thereof
Inventor: BOBOTAS GEORGE
IPC: A61K31/19
Filed: 2005-12-05
Abstract: A method and composition for blood lipid therapy that comprises administering to the subject an effective amount of a PPAR agonist and/or antagonist and an omega-3 fatty acid. The methods and compositions include combination products or concomitant therapy for the treatment of subjects with hypertriglyceridemia, hypercholesteremia, mixed dyslipidemia, vascular disease, artherosclerotic disease and related conditions, obesity, the prevention or reduction of cardiovascular and vascular events, the reduction of insulin resistance, fasting glucose levels and postprandial glucose levels, and/or the reduction of incidence and/or the delay of onset of diabetes.
Patent EA-010046-B1 (EA)
Title: Modular formwork and a clamping device for connecting thereof
Inventor: DOROFEEV OLEG IVANOVICH
IPC: E04G11/08
Filed: 2007-06-25
Abstract: The invention relates to construction industry, in particular, to modular formwork and a clamping device for connecting it. The modular formwork can be used for constructing walls and after hardening concrete mixture is disassembled completely and assembled anew for subsequent placement of concrete mixture. The modular formwork comprises panels, each in the form of rectangular box with a forming plate 1 and connecting profiles 2 forming side panels of the rectangular box structure, Each clamping device comprises a housing with a carrying element 6, rigid supports 7, a clamping plate 8 and an eccentric 9. The carrying element 6 of the clamping device housing has a rectangular section, the supports are made protruding in one transversal direction of the carrying element 6 along its lateral sides 10. The clamping plate 8 is hingedly connected on the carrying element 6 of the housing with clamp end projections being opposite supports 7 and positioning connecting bridge 12 on the other side of the carrying element 6. The eccentric 9 is mounted on the carrying element 6 from the side of the supports 7 capable to rotate and interact by its side working surface 13 with a side surface 14 of the connecting bridge 12 of the clamping plate 8. Radial projections 21, 22 and 23 are provided on the outer end surface of the eccentric 9. The projection 21 (fig.3) is oriented in the direction of maximum distance from the eccentric 9 rotation axis to the working surface 13, wherein projections 22 and 23 are oriented perpendicular to projection 21in opposite directions.
Patent EA-014532-B1 (EA)
Title: Intranasal or inhalation administration of virosomes
Inventor: KERSTEN ALEXANDER J
IPC: A61K39/145
Filed: 2007-03-21
Abstract: The present invention provides a composition of influenza virosomes comprising reconstituted envelopes of said virus, wherein the viral envelopes are entirely derived from influenza viral particles, wherein no lipids are added from the external sources to the reconstituted virosomes, wherein the virosomes comprise the influenza antigens haemagglutinin and/or neuraminidase or derivatives thereof, wherein no separate adjuvants and/or immune stimulators are added to the composition, and wherein the composition is for intranasal or inhalation administration, which composition is characterized in that a single intranasal or inhalation administration to a human being is sufficient for the induction of a systemic immune response and/or a local immune response and/or a cytotoxic lymphocytes response against said influenza antigens, and the systemic response is in accordance with the CHMP criteria for influenza vaccines, and wherein the dose of haemagglutinin per viral strain per intranasal or inhalation administration is lower than or equal to 30 microgram. The invention also provides the use of reconstituted influenza virosomes for the industrial production of vaccine formulations.
Patent EA-017039-B1 (EA)
Title: Use of phospholipase a in production of cakes and method for production thereof
Inventor: MASTENBROEK JOSE
IPC: A23L35/00
Filed: 2008-01-30
Abstract: The invention relates to a novel use of a phospholipase A in the production of cake to improve at least one of the properties selected from the group consisting of: (i) batter viscosity, (ii) specific density, (iii) initial crumb softness, (iv) crumb pore homogeneity, (v) crumb pore diameter, (vi) crumb softness upon storage, (vii) shelf life, and/or (viii) cake volume. The invention also relates to a novel use of phospholipase A in the production of cake to enable reduction of the amount of eggs and/or fat used in the recipe.
Patent EA-016889-B1 (EA)
Title: Apparatus and method for providing a container with a customized design
Inventor: SCHULTCHEN ARNE
IPC: G06T11/60
Filed: 2008-04-30
Abstract: An apparatus for providing a container (3) having at least one surface with a customized design, comprises a memory containing at least one set of data comprising a plurality of design elements (320, 321, 322); a user interface (10) comprising interface means and display means enabling the consumer to interact with the apparatus to allow the generation of a customized design of at least one surface of a virtual whitepack through selection and placement of at least one of the design elements (320, 321, 322) and through visual representation of the selected at least one design element (320, 321, 322) on the at least one surface of the virtual whitepack, an application unit (13) for applying the customized design of the at least one surface of the virtual whitepack to at least one surface of a whitepack (4) so as to obtain the container (3); having the at least one surface with the customized design, and a logic control unit (12) to which the memory, the user interface and the application unit are connected.
Patent EA-021002-B1 (EA)
Title: Training stand for performing laboratory studies in electrical engineering, electronics and programming
Inventor: MIKHALTSOV ALEXANDER PETROVICH
IPC: G09B23/18
Filed: 2011-03-29
Abstract: The invention relates to training means and can be used in individual and group training in designing electronic circuits and programming algorithms for performance of laboratory works and demonstration experiments related to electric and radio engineering, electronics and programming. The aim of the invention is to develop a universal stand for performing laboratory works in the process of studies with electrical, electronic and radio elements which staying universal would allow to solve narrow tasks to master experience and skills in designing and studying electronic and electric schemes and components. The assigned task is characterized in that the stand further comprises power supply units, measuring instruments, control devices installed on the stand base. Panels are variable with a set of precommutated electro and radio elements, wherein the base is also provided with multicontact split connecting elements for an electric connection of a variable panel with the power supply units, measuring instruments blocks and control blocks. An image of a precommutated electric or electronic scheme is displayed on the front surface of the variable panel, wherein a part of commutating conductors and/or electric components is absent, and connecting contacts of these elements are led out on the front surface of the variable panel for subsequent manual commutation. There are other differences from the prototype. The advantages of said training means are a substantial increase of performed laboratory and experimental studies, ability to master programming skills and creation of simple and complex programming algorithms.
Patent EA-019274-B1 (EA)
Title: Method of measuring oil borehole production and device therefor
Inventor: ALIEV TELMAN ABBAS OGLY
IPC: G01F1/38
Filed: 2011-03-10
Abstract: The invention relates to oil production industry, in particular to measuring engineering and can be used in systems of centralized control for measuring production of two-phase three-component borehole production. The essence of the invention consists in a method of measuring oil boreholes production, which comprises measuring liquid level in a separation measuring tank. In addition pressure difference is measured between the oil liquid level in the separation measuring tank and liquid level in a leveling level of a differential manometer installed on the separation measuring tank, and oil liquid production and mass oil production and formation water are determined by calculation. Gas output is further calculated in normal conditions by measured pressure difference in a diaphragm mounted on the gas discharge line from the separation measuring tank. The invention also comprises a device for automatic measuring oil boreholes production including a separation measuring tank, a float, level gage with a magnetic indicator, a distribution battery, actuating mechanisms mounted on draining and supplying lines and a control block. The device is further provided with two differential manometers. One manometer is connected via the distributing vessel filled with separating fluid with lower and medium part of the separation measuring tank below the supposed oil liquid level. The other manometer is connected via a diaphragm to a pipeline of gas discharge to the collector. The outlets of the manometers are connected with the control block. The claimed invention provides to measure a borehole production not only for fuel and formation, but also for assist gas, to enhance reliability borehole production measurement for all production components, as well as frequency of measurement which result in controlling and managing borehole operation in the most operative manner.
Patent EA-020577-B1 (EA)
Title: Process to make olefins from oxygenates
Inventor: NESTERENKO NIKOLAI
IPC: C07C1/20
Filed: 2009-06-24
Abstract: The present invention relates to a process to make light olefins, in a combined XTO-OC process, from an oxygen-containing, halogenide-containing or sulphur-containing organic feedstock comprising: a) providing a catalyst comprising zeolitic molecular sieves containing 10 member and larger channels in their microporous structure; b) providing an XTO reaction zone, an OC reaction zone and a catalyst regeneration zone, said catalyst circulating in the three zones, such that at least a portion of the regenerated catalyst is passed to the OC reaction zone, at least a portion of the catalyst in the OC reaction zone is passed to the XTO reaction zone and at least a portion of the catalyst in the XTO reaction zone is passed to the regeneration zone; c) contacting said oxygen-containing, halogenide-containing or sulphur- containing organic feedstock in the XTO reactor with the catalyst at conditions effective to convert at least a portion of the feedstock to form a XTO reactor effluent comprising light olefins and a heavy hydrocarbon fraction; d) separating said light olefins from said heavy hydrocarbon fraction; e) contacting said heavy hydrocarbon fraction in the OC reactor with the catalyst at conditions effective to convert at least a portion of said heavy hydrocarbon fraction to light olefins.
Patent EA-020937-B1 (EA)
Title: Rotary vibrating mill
Inventor: GANIEV RIVNER FAZYLOVICH
IPC: B02C13/18
Filed: 2011-05-26
Abstract: The device relates to mills for fine and superfine disintegration and activation of materials. The rotary vibrating mill comprises a cylindrical body (1), on the upper end wall (2) of which a loading nozzle (3) and unloading nozzle (4) are arranged, and, on the internal surface, there are deflectors, a shaft (5), a drive (6) for rotating the shaft, a disc (7) which is mounted on the shaft and has openings (8) and beaters (9), and a motor (10) for torsional oscillations of the body, the motor being connected to the lower end wall (11) of the body. The use of the proposed device makes it possible to increase the productivity of rotary vibrating mills by 1.5-2 times without additional consumption of electric power.
Patent EA-022361-B1 (EA)
Title: Crosslinkable polymer composition, cable with advantageous electrical properties and process for producing the same
Inventor: SMEDBERG ANNIKA
IPC: C08F10/00
Filed: 2010-11-03
Abstract: The invention relates to a crosslinked polymer composition comprising a crosslinked polyolefin, wherein the polymer composition comprises prior to crosslinking a polyolefin and peroxide which is in an amount of less than 35 mmol -O-O-/kg polymer composition and wherein the polyolefin is before the crosslinking an unsaturated LDPE (a low density polyethylene) polymer, which is selected from an unsaturated homopolymer or an unsaturated copolymer of ethylene with one or more comonomer(s), and comprises vinyl groups in the amount of higher than 0.05/1000 carbon atoms. A method for reducing electrical conductivity of the crosslinked polymer composition of a power cable is also provided. The power cable is crosslinked before the end use thereof and comprises a conductor which is surrounded by at least one layer, comprising the above polymer composition. Also disclosed are the crosslinkable power cable comprising the conductor which is surrounded by at least one layer comprising the crosslinked polymer composition of the invention, and a method for producing such crosslinkable power cable.
Patent EA-020724-B1 (EA)
Title: Heterocyclic compound, medicament comprising same and methods for use thereof
Inventor: HOMMA MISAKI
IPC: C07D519/00
Filed: 2011-02-16
Abstract: Disclosed is a compound useful as a prophylactic or therapeutic agent for cancer. Specifically disclosed is a compound represented by formula (I)wherein each symbol is as defined in the description or a salt thereof, which is useful for the prevention or treatment of cancer.
Patent EA-022579-B1 (EA)
Title: Gas valve unit having two gas outlets
Inventor: NAUMANN JOERN
IPC: F23N1/00
Filed: 2011-05-10
Abstract: The subject matter of the invention is a gas valve unit for setting gas volumetric flows to a twin-circuit gas burner of a gas unit, in particular a gas cooking unit, wherein the gas valve unit has a gas inlet (3) and two gas outlets (11, 12). According to the invention, the gas volumetric flow to at least one of the gas outlets (12) can be set in a multiple-stage manner. In a zero position of the gas valve unit, the gas volumetric flow to both gas outlets (11, 12) is interrupted. In a switching position which is adjacent to the zero position, the gas volumetric flow which can be set in a multiple-stage manner is set to a maximum value.; In order to set the gas volumetric flow which is fed to a first gas outlet (11), the gas valve unit has at least two first open/shut valves (15) and at least two first throttle points (17), preferably at least three first open/shut valves (15) and at least three first throttle points (17). In order to set the gas volumetric flow which is fed to a second gas outlet (12), the gas valve unit has at least two second open/shut valves (16) and at least two second throttle points (18), preferably at least four second open/shut valves (16) and at least four second throttle points (18). In order to control the open/shut valves (15, 16), at least two magnetically active bodies (5, 6) are provided, wherein a first magnetically active body (5) is formed by a ferromagnetic body and a second magnetically active body (6) is formed by a permanent magnet.; At least one first open/shut valve (15.3) has a permanent magnet (13), in such a way that said first open/shut valve (15.3) can be controlled as a function of the position of the first magnetically active body (5) which is formed by a ferromagnetic body.
Patent EA-023096-B1 (EA)
Title: Plate-type semi-automatic dosing apparatus
Inventor: PITSAEV MAGOMED MUKHTAROVICH
IPC: G01F11/24
Filed: 2013-05-17
Abstract: The invention relates to devices for volumetric dosing materials and is intended for use in the food industry for forming doses of granular products, in particular, for dosing sunflower seeds, nuts and for sale thereof. The technical result consists in higher precision and higher speed of the dosing process, possibility of controlling the quantity of the sold product, connection of a receipt printer, remote communication of information on operation of the semi-automatic apparatus and voice announcement of completion of the product dosing process. The technical result is attained by provision of a plate-type semi-automatic dosing apparatus comprising a casing fixed on a baseplate and having windows for feed and discharge of the product being dosed, and a plate mounted inside the lower part of the casing, rotatable around the vertical axis and connected to a rotation drive. The rotation drive is mounted in the upper part of the casing; the lower part of the casing is made in the form of two funnels, a large one and a small one; the small funnel accommodates a plate made in the form of a solid disk with two angles (α and β): α is a natural flowing angle of granular products, and β is a calculated angle of inhibition of granular products; the small funnel has a nut for adjusting the dose quantity; a control panel, an indicator for visual control of dosed product quantity and a lighting device are built in the casing; a system board with a connector for personal computer and receipt printer connection, a system board for remote transmission of information on operation of the plate-type semi-automatic dosing apparatus, and an audio device for announcement of completion of the product dosing are mounted on the baseplate.