baber/WOPTO huggingface dataset:
Patent NZ-522474-A (NZ)
Title: Thrombopoietin mimetics
Inventor: DUFFY KEVIN J
IPC: C12N5/0789
Filed: 2001-05-24
Abstract: Thrombopoietin (TPO) mimetics and their use as promoters of thrombopoiesis and megakaryocytopoiesis are disclosed. Also disclosed are processes and intermediates used in the preparation of these compounds; a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Patent NZ-524814-A (NZ)
Title: Talaromyces xylanases
Inventor: VAN DEN HOMBERGH JOHANNES PETR
IPC: A23K30/18
Filed: 2000-09-21
Abstract: A xylanase polypeptide comprises: (a) the amino acid sequence from amino acids 23 to 408 of SEQ ID NO:2; or a variant of (i) which is capable of cleaving xylan and has at least 70% identity to the amino acids 23 to 408 of SEQ ID NO:2. The polypeptide is obtainable from a fungus or an organism of the genus Talaromyces such as the species Talaromyces emersonii. Polynucleotides, vectors, host cells and composition are described. A plant or xylan-containing material can be treated, to degrade, hydrolyse, modify xylan in the material, degrade or modify plant cell walls or cleave xylopyranosyl or b-D-xylan subunits of the material, by contacting the material with the protein. The polypeptide can also be used in a method of treating plant material, improving filterability and/or reducing viscosity of xylan-containing liquids, improving filterability or clarifying alcoholic liquids (e. g. beer, wine) or fruit or vegetable juices, hydrolysing agricultural residues, in recycling materials (e. g. containing paper) in paper making for thickening foodstuffs and/or extracting desirable materials (e. g. coffee, plant oil, starch), processing plant pulp, juice or extract, improving loaf volume, bread quality or reducing the stickiness of dough, in brewing, beer or wine-making, distilling, recycling, biomethanation, dental hygiene, leather treatment, paper manufacture, fruit or vegetable juice or extract treatment, textile treatment or manufacture, baking or bread making, treating flower bulbs, preparation of food or foodstuffs or in an animal feed.
Patent NZ-525147-A (NZ)
Title: (Dihydro)isoquinoline derivatives as phosphodiesterase inhibitors
Inventor: BUNDSCHUH DANIELA
IPC: C07D217/14
Filed: 2001-11-08
Abstract: A compound of formula (I); a drug comprising at least one compound of formula (I) and pharmaceutical auxiliary and/or carrier substances; and the use of at least on compound of formula (I) for producing drugs for treating diseases which can be influenced positively be inhibiting PDE7 and for treating respiratory tract diseases.
Patent NZ-526453-A (NZ)
Title: Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes
Inventor: CHAMBERS ROBERT JAMES
IPC: C07D405/12
Filed: 2001-12-06
Abstract: Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of the formula (I) are disclosed, wherein: j is 0 or 1 provided that when j is 0, n must be 2; k is 0 or 1; m is 0, 1, or 2; n is 1 or 2; W1 is -0-; or -S(=O)t-, where t is 0, 1, or 2; or -N(R3)-; W2 is -O-CRARB- or is absent; Y is =C(R1a)- or -[NÞ(O)k]- where k is 0 or 1; RA and RB are -H; -F; -CF3; -(C1-C4)alkyl; -(C3-C7)cycloalkyl; phenyl; or benzyl substituted with 0 to 3 substituents R10; or RA and RB are taken together, but only in the case where m is 1, to form a spiro moiety; RC and RD have the same meaning as RA and RB except that one of them must be -H, R1 and R2 are -H; -F; -Cl; -CN; -NO2; (C1-C4)alkyl; -(C2-C4)alkynal; fluorinated-(C1-C3)alkyl; -OR16; and -C(=O)NR22aR22b; R3 is -H; -(C1-C3)alkyl; phenyl; benzyl; or -OR16; R4, R5 and R6 in addition to other meanings may be taken together to form, e.g., form (II): Q1, Q2 and Z are as defined in the application.
Patent NZ-529603-A (NZ)
Title: Synthetic molecules having biological activity similar to PIM (acyl glycerol phosphatidylinositol manno-oligosaccharide) activity
Inventor: SINGH-GILL GURMIT
IPC: C07H15/04
Filed: 2003-11-18
Abstract: Disclosed herein are synthetic molecules of formula A-B-E-D (wherein A, B, E & D are as defined in the specification) having biological activity similar to PIM (acyl glycerol phosphatidylinositol manno-oligosaccharide) activity, for use in the treatment and prevention of inflammatory or immune cell mediated diseases or disorders.
Patent NZ-531327-A (NZ)
Title: Enhancing treatment of MDR (multi-drug resistance) cancer with adenosine A3 antagonists
Inventor: BOREA PIER ANDREA
IPC: A61P25/00
Filed: 2003-06-24
Abstract: Disclosed herein is a use of an effective amount of a high affinity adenosine A3 receptor antagonist for the production of a pharmaceutical composition for countering multi-drug resistance in cancers expressing P-glycoprotein or MRP and for synergistically enhancing the chemotherapeutic treatment of cancer expressing adenosine A3 receptors by a chemotherapeutic cancer agent that develops P-glycoprotein (P-gp) or multi-drug resistance-associated protein (MRP) dependent multi-drug resistance (MDR).
Patent NZ-532284-A (NZ)
Title: Benzoxazine and Benzothiazine derivatives and parmaceutical compositions containing them
Inventor: BHUNIYA DEBNATH
IPC: A61P3/10
Filed: 2002-10-15
Abstract: Disclosed are compounds of formula (I), wherein: X is O or S, W is NR12, -C(=O)-(CR10R11)oNR12, or -O-aryl-(CR10R11)oNR12, Ar is a optionally substituted aromatic or heterocyclic group, and the remaining substituents are defined herein. Also disclosed are processes for producing the compounds and intermediates used in the processes. The compounds of formula (I) are used in the manufacture of medicaments for use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic drugs.
Patent NZ-536771-A (NZ)
Title: Method for fractional crystallisation of a molten metal
Inventor: DE VRIES PAUL ALEXANDER
IPC: C22B7/00
Filed: 2003-06-27
Abstract: A method for fractional crystallisation of an at most partially solidified molten metal is disclosed, wherein a layer of at most partially solidified molten metal to be crystallised is cooled by a layer of cooling liquid (for example a molten salt can be used as a cooling liquid), which is present above and/or below the layer of at most partially solidified molten metal so as to crystallise the molten metal, which layer of cooling liquid contacts the layer of at most partially solidified molten metal. The method is suitable removing unwanted elements such as Cu, Fe, Ga, Mg, Mn, B, Si, Sn, Zn or Ni from molten aluminium and is used in the refining of aluminium metal.
Patent NZ-540141-A (NZ)
Title: Improvements in or relating to adhesives
Inventor: GRIGSBY WARREN JAMES
Filed: 2003-11-20
Abstract: Disclosed is an adhesive comprising a resin and a hardener, wherein the resin comprises pine bark tannin, a suitable phenol-resorcinol-formaldehyde resin and one or more diluents or solvents; and wherein the hardener composition comprises 2-amino-2-(hydroxymethyl)-1,3-propanediol, formaldehyde, one or more solvents and water; and both the hardener and the resin have a neutral pH. Also disclosed are the hardener and resin above and methods of producing and using them.
Patent NZ-541763-A (NZ)
Title: Fire collar for location in a concrete slab
Inventor: TRUSS JAMES WALTER GEORGE
IPC: F16L55/10
Filed: 2004-02-10
Abstract: A fire collar (10), for location in a concrete slab (46) around a deformable conduit (14), has a housing with a passageway (16) through which the conduit (14) passes. The collar (10) has a housing (12) in which are located two compression springs (18, 20) with arms (30, 32) which are held against the force of the springs (18, 20) by fusible Iinks (34, 36). When the heat of a fire on one side of the slab (46) causes the fusible links (34, 36) to soften or melt, the force of the springs (18, 20) causes the spring arms (30, 32) to rotate towards the conduit (14), engaging the conduit (14) and collapsing it. An intumescent layer (42) may be provided around the conduit (14) to assist in collapsing it.
Patent NZ-542272-A (NZ)
Title: Antineoplastic combinations of EKB-569 and CCI-779
Inventor: CONSIDINE JOHN LEO
IPC: A61K31/47
Filed: 2002-08-06
Abstract: Disclosed are processes and intermediates for the preparation of [4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide (EKB-569).
Patent NZ-542485-A (NZ)
Title: Means for detecting leaks between plates in a plate heat exchanger by using thermal imaging
Inventor: WATSON JOHN OLIVER
Filed: 2005-09-19
Abstract: A method for testing for fluid leaks between plates in a plate heat exchanger without dismantling is disclosed. A camera 8 that is capable of producing a thermal image is positioned near the plate heat exchanger 1. By moving the camera around either mechanically or manually the heat signature of various locations in the plate heat exchanger can be measured. Any leaks present will show up as a large temperature difference on the heat signature. The invention has particular application to the dairy industry.
Patent NZ-545576-A (NZ)
Title: Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
Inventor: HORVATH STEPHANE
IPC: C07D405/12
Filed: 2006-02-27
Abstract: Disclosed is a beta-crystalline form of ivabradine hydrochloride of formula (I) characterised by the powder X-ray diffraction diagram as described in the specification. Also disclosed are processes for the preparation of said crystalline form, pharmaceutical compositions containing said crystalline form, and the use of said crystalline form as a bradycardic, in particular for the treatment of various clinical situations of myocardial ischaemia.
Patent NZ-550427-A (NZ)
Title: Downlight with adjustment to alter beam of light in shape or intensity
Inventor: AUSTIN FRANCIS WILLIAM
Filed: 2006-10-06
Abstract: A downlight is provided for height adjustment so that lamp 5 can be moved vertically relative to a surrounding reflector. Other forms of adjustment are disclosed for the downlight.
Patent NZ-551866-A (NZ)
Title: S-tenatoprazole sodium monohydrate salt and the use thereof in the form of a proton pump inhibitor
Inventor: COHEN AVRAHAM
IPC: A61P1/04
Filed: 2005-06-17
Abstract: The disclosure relates to a S-tenatoprazole sodium monohydrate salt of formula (I). This compound is suitable for a therapeutic use in the treatment of digestive pathologies where the inhibition of acid secretion must be effective and prolonged and are particularly useful for treating digestive diseases, gastro-oesophageal reflux disease and digestive bleeding in polymedicamented patients.
Patent NZ-552276-A (NZ)
Title: Prodrugs of HIV protease inhibitors
Inventor: DEGOEY DAVID A
IPC: A61K31/661
Filed: 2005-06-29
Abstract: Disclosed are phosphor-ester prodrugs having formula (I), (II) or (III) where A is the substituent (i) and the rest of the variables are as disclosed in the description. Also disclosed are processes for making prodrugs of formula (I); pharmeacutical composistions containing a prodrug having formula (I), (II), or (III) and the use of a prodrug of formula (I), (II) or (III) in the preparation of a medicament for inhibiting HIV protease, for treating HIV infection, for improving the pharmacokinetics of a drug or for increasing human blood levels of a drug.
Patent NZ-552726-A (NZ)
Title: Beer dispensing system with gas pressure reservoir, and pressure sensing and signalling system
Inventor: WAUTERS ALBERT
Filed: 2003-11-25
Abstract: A home beer dispensing apparatus has a keg having a self-contained bag filled with a beer and a pressure system. The pressure system creates a pressurized air space between the keg inner walls and the bag to assist in the dispensing of the beer. The pressure system has a keg one-way air valve mounted to a top wall of the keg to permit entry of pressurized air into the keg. The pressure system has a pressure reservoir mounted in the dispensing apparatus outside the keg and in fluid flow communication with the keg one-way valve. The reservoir stores a charge of pressurized air and supplies at least a portion of this charge to the keg through the keg air valve when the dispensing apparatus is operated to dispense the beer. The reservoir provides a reserved charge of pressurized gas that is on hand to reduce dampening pressure fluctuations during beer dispensing which can result in beer frothing, especially during the early stages of beer dispensing when the air head space in the keg is small. Further, the apparatus may also have a pressure sensing system adapted to measure time rate of pressure change in the keg. The apparatus has a signalling device responsive to the time rate of pressure change in the keg to produce a signal related to volume of beer remaining in the bag. Preferably, the signal is displayed visually on the dispensing apparatus. This application is directed to the pressure sensing and signalling system.
Patent NZ-556611-A (NZ)
Title: Method for steam reforming carbonaceous material
Inventor: ZWIERSCHKE JAYSON
IPC: C10J3/16
Filed: 2006-01-18
Abstract: Disclosed is a method for steam reforming carbonaceous material into synthesis gas, said method comprising: feeding an input of carbonaceous material into a steam reforming rotary kiln, wherein the steam reforming rotary kiln is externally heated; agitating the carbonaceous material using the steam reforming rotary kiln; heating the carbonaceous material within the rotary kiln to an elevated reforming temperature of from about 650 to 1100 degrees Celsius in the presence of water or steam; reforming the carbonaceous material such that the carbonaceous material undergoes substantially complete conversion via a steam reforming reaction to form synthesis gas and a minimal amount of inert solid slag.
Patent NZ-560314-A (NZ)
Title: Live attenuated rotavirus vaccine for oral administration
Inventor: VANDE VELDE VINCENT
IPC: A61K39/15
Filed: 2006-02-15
Abstract: A liquid rotavirus immunogenic composition suitable for oral administration to a human infant, comprising a rotavirus antigen, a sugar and a carboxylate. The composition has a pH of between pH 5.0 and pH 8.0 and comprises less than 1 mM phosphate and the carboxylate is derived from a dicarboxylic acid with a pKa > 4. Suitable carboxylates are adipate, malate, succinate, malonate, glutarate, maleate, fumarate and tartarate. The composition is used as a vaccine for infants to prevent or treat gastroenteritis.
Patent NZ-564689-A (NZ)
Title: Novel piperidine carboxylic acid amide derivatives
Inventor: BEZENCON OLIVIER
IPC: A61K31/451
Filed: 2006-05-23
Abstract: Disclosed are piperidine carboxylic acid amide compounds of formula (I) wherein R1 is cycloalkyl and the remaining substitutents are as defined in specification. Also disclosed are pharmaceutical compositions containing said compounds and their use as rennin inhibitors and treating diseases such as cardiovascular events and renal insufficiency.
Patent NZ-566055-A (NZ)
Title: Modified landplaster as a wallboard filler
Inventor: BLACKBURN DAVID R
IPC: B32B5/16
Filed: 2006-08-25
Abstract: Disclosed is a gypsum slurry comprising: calcium sulfate hemihydrate; water; and calcium sulfate dihydrate coated with a hydrophilic, dispersible coating, wherein said coating is less soluble than calcium sulfate hemihydrates and wherein said coating is at least one of the group consisting of a phosphate, a phosphonate, a hydroxide and a carbonate coating. The hydrophilic, dispersible coating serves as a modifier to enhance the ability of the dispersant to fluidize the gypsum slurry. Also disclosed is method of making a wallboard panel from the gypsum slurry.
Patent NZ-568762-A (NZ)
Title: Use of an inhibitor of tissue factor signaling in the manufacture of a medcament for inhibiting or suppressing tissue factor/tissue factor VIIa signaling involving protease activated receptor 2 in a mammal
Inventor: RUF WOLFRAM
IPC: A61K39/395
Filed: 2006-11-06
Abstract: Disclosed is the use of an inhibitor of tissue factor signaling in the manufacture of a medicament for inhibiting or suppressing tissue factor/factor VIIa (TF/VIIa) signaling involving protease activated receptor 2 (PAR2) in a mammalian subject suffering from an angiogenesis-related disease, or inflammation, wherein the inhibitor does not interfere with hemostasis in the mammalian subject.
Patent NZ-569261-A (NZ)
Title: Water-soluble films comprising low-viscosity alginates
Inventor: STENBERG KJELL
IPC: A61P29/00
Filed: 2006-12-22
Abstract: Disclosed herein is a method of manufacturing a bioadhesive film comprising, as a film-forming agent, an alginate salt of monovalent cation or a mixture of alginate salts of monovalent cation, the film-forming agent having a mean guluronate (G) content of from 50 to 85% by weight, a mean mannuronate (M) content of from 15 to 50% by weight, a mean molecular weight of from 30,000 g/mol to 90,000 g/mol and being such that a 10% aqueous solution thereof at a temperature of 20°C has a viscosity of 100-1000 mPas, as measured at a shear rate of 20 rpm by use of a Brookfield viscometer with a spindle No.2, by dissolving the film-forming agent in a solvent or mixture of solvents so as to obtain a liquid composition, distributing the composition onto a solid surface, and permitting the composition to dry on the surface, wherein said method does not include a melting step.
Patent NZ-573600-A (NZ)
Title: Direct smelting vessel and cooler therefor
Inventor: MEDINA HECTOR
IPC: C21B7/10
Filed: 2007-05-18
Abstract: Disclosed is a cooling element for location in a refractory lined hearth of a direct smelting vessel below solids injection lances in the smelting vessel. The cooling element includes a hollow open-backed shell structure with a water cooled base, top, front and side walls formed integrally in a cast structure. The cooling element has a shape adapted for co-location with other of the cooling elements in the hearth to form a circular ring cooler with the water cooled side walls of the cooling elements providing water cooling of clearance gaps between adjacent cooling elements. A direct smelting vessel incorporating the cooling element is also claimed.
Patent NZ-573944-A (NZ)
Title: Functional dairy product and process for producing functional food with enhanced ACE inhibitory activity by adding EMC (enzyme modified cheese)
Inventor: SUZUKI MASAYUKI
IPC: B60C17/06
Filed: 2003-11-21
Abstract: Disclosed is a process for producing a functional food, wherein protease enzyme-modified cheese having 9,000 units/g or more of an ACE inhibitory activity is added to cheese or yoghurt in an amount of 0.01% to 1.5% by weight, wherein at least the protease enzyme-modified cheese confers 5,000 units or more of angiotensin converting enzyme inhibitory activity per daily consumption of at least 15g of the cheese or at least 200g of the yoghurt. (62) (62) Divided Out of 540822
Patent NZ-582749-A (NZ)
Title: Method, typically computer controlled, for controlling rate of flow through a hopper by comparing actual weight of hopper and material with predetermined weight to raise or lower discharge valve
Inventor: SCHWASS TREVOR DOUGLAS ANTHONY
IPC: B65G69/18
Filed: 2004-12-23
Abstract: This disclosure relates to a material discharge apparatus (1), method and computer program for controlling the flow rate of flowable material being conveyed through a hopper (2), the apparatus (1) typically including a hopper (2) having an inlet opening (4) at the top and a discharge outlet (5) at the base of the hopper (2), and a valve means (7) configured and arranged in the hopper, the valve means (7) having a lower end portion adjacent the discharge outlet (5) forming a gap between the hopper and the valve means for material to flow therethrough, the valve means and/or the hopper being adapted to move relative to the other, in use, for controlling the rate of discharge of material through the gap. Method steps and a computer controlled process are claimed for this application. The steps are: A. an actual measurement of weight of a hopper with material flowing therethrough is compared to a preset measurement of weight representing a preferred flow rate through the hopper. B. If the actual measurement of weight is more than the preset measurement of weight, the valve means in the hopper is actuated to raise the valve to increase the discharge rate of material flowing through the hopper. C. If the actual weight is less than the preset measurement of weight the valve means is actuated to lower the valve in the hopper to decrease the discharge rate of material flowing through the hopper. D. Steps are repeated until the material has been discharged through the hopper. (62) Divided Out of 547546
Patent NZ-585420-A (NZ)
Title: Encoding and interleaving using a low-density parity check code
Inventor: YOKOKAWA TAKASHI
IPC: H03M13/11
Filed: 2008-11-26
Abstract: 585420 Disclosed is a data processing apparatus (11) which interleaves data of a low-density parity check (LDPC) code. The apparatus includes re-arrangement means (22) for carrying out column twist interleaving for each column of an LDPC code stored in storage means. The interleaving is a rearrangement process for re-arranging the code bits of the LDPC code including changing the writing starting position when the code bits of the LDPC code are to be written in the column direction of the storage means. The LDPC code includes an information matrix which is a portion of a parity check matrix which corresponds to information bits of the LDPC code. The LDPC code is transmitted as a symbol or symbols each formed from two or more code bits thereof. The symbol is formed from the code bits of the LDPC code which are written in a column direction of storage means for storing the code bits of the LDPC code in a row direction and the column direction and are read out in the row direction from said storage means.
Patent NZ-585546-A (NZ)
Title: Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration
Inventor: BELL ROBERT G
IPC: A61K/
Filed: 2004-07-16
Abstract: Provided is the use of estrogen and progestin in the manufacture of a medicament for treating a catamenial symptom in a female in need thereof, wherein the medicament is formulated into dosage forms of: (a) 60 to 110 dosage forms comprising estrogen and progestin; and (b) 2 to 10 dosage forms consisting essentially of estrogen; wherein each of the 60 to 110 dosage forms in (a) is formulated for sequential and continuous administration each day for 60 to 110 consecutive days followed consecutively by sequential and continuous administration of each of the 2 to 10 dosage forms in (b) each day for 2 to 10 consecutive days. The diseases associated with catamenial symptoms include asthma, rheumatoid arthritis, seizure disorders, multiple sclerosis, diabetes and migraine.
Patent NZ-586335-A (NZ)
Title: Process for the preparation of 6-substituted-1-(2h)-isoquinolinones
Inventor: ROSSEN KAI
IPC: C07D211/42
Filed: 2008-12-22
Abstract: Disclosed is a process to make 6-substituted-1-(2H)-isoquinolinone of formula (I) or a salt thereof comprising the steps of reacting a compound of formula (II) with a compound of formula (III) to give a compound of formula (IV) which was further reacted with a compound of formula (V) to yield a compound of formula (VI). A compound of formula (VI) was cyclised to give a compound of formula (I) which was optionally unprotected and optionally converted into a salt. The variables of the formulas are as disclosed in the description. Also disclosed is a formula of compound (IV) and (VI); and the use of a compound of formula (IV) or (VI) in preparing a compound of formula (I).