baber/WOPTO huggingface dataset:
Patent NZ-335953-A (NZ)
Title: Method for producing N-substituted 3-hydroxypyrazoles
Inventor: VOGELBACHER UWE JOSEF
IPC: C07D231/20
Filed: 1997-12-04
Abstract: A process for preparing N-substituted 3-hydroxypyrazoles of the formula I, wherein, R1 is unsubstituted or substituted C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C3-C10 cycloalkyl, aryl selected from phenyl and naphthyl, heteroaryl selected from furyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, imidazolyl, pyridyl, pyridazinyl, pyrimidinyl and triazinyl, R2 and R3 are hydrogen, cyano, halogen and unsubstituted or substituted C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C3-C10 cycloalkyl, unsubstituted or substituted aryl selected from phenyl and naphthyl, heteroaryl selected from furyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, imidazolyl, pyridyl, pyridazinyl, pyrimidinyl and triazinyl, where the substituents R1, R2 and R3 are inert under the reaction conditions, by oxidizing a pyrazolidin-3-one of the formula II which comprises carrying out the reaction of the water-soluble compounds of the formula II in water in the presence of a base using oxygen as oxidizing agent.
Patent NZ-336097-A (NZ)
Title: Method of increasing seafood production in the barren ocean by adding an non-precipitating iron chelate and optionally another nutrient to the ocean
Inventor: MARKELS JR
IPC: A01K61/00
Filed: 1997-12-11
Abstract: A method of increasing seafood production in the open ocean comprises the following steps: a. testing an area of the surface of the open ocean, in order to determine a first nutrient that is missing to a significant extent and a second nutrient that is missing to a significant extent; wherein the first missing nutrient is iron; b. applying separately a first fertilizer which comprises the first missing nutrient and a second fertilizer which comprises the second missing nutrient, to fertilize the area of the surface of the open ocean with an appropriate amount of the first missing nutrient and an appropriate amount of the second missing nutrient, wherein the first fertilizer comprises an iron chelate, and the first fertilizer releases the first missing nutrient in a form that does not precipitate to any substantial extent; and c. harvesting at least a portion of the increased production of seafood that results from the fertilization of the open ocean. Also disclosed is a method of open ocean fertilisation comprising the step of applying a fertiliser to fertilise the surface of the open ocean with a nutrient, wherein the fertiliser comprises an iron chelate and the fertiliser releases the iron in a form that does not precipitate to any substantial extent.
Patent NZ-500935-A (NZ)
Title: Ectopic gene targeting by mapping the site of interaction between two chromosomes
Inventor: CHARTRAND PIERRE
IPC: C12N15/11
Filed: 1998-05-29
Abstract: A linear DNA vector and to a method for identifying chromosomal regions having a physical proximity within a living cell, and/or for locating in chromosomes of a living cell a DNA double strand break having a physical proximity with a known non-repetitive DNA sequence. The linear DNA vector has a first end which comprises a nucleotide sequence capable of homologous recombination to a first region of a cell chromosome which comprises a known non-repetitive DNA sequence. The linear DNA vector also has a second end which comprises a nucleotide sequence non-homologous to the chromosomes of the cell and being capable of illegitimate integration with a second region of a chromosome in physical proximity to the first chromosomal region.
Patent NZ-503717-A (NZ)
Title: Apolipoprotein A-I (ApoA-I) agonists and their use to treat dyslipidemic disorders and prevent toxic shock
Inventor: BUTTNER KLAUS
IPC: C07K7/00
Filed: 1998-09-28
Abstract: Peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I are described.  The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia and toxic shock.
Patent NZ-505302-A (NZ)
Title: Flash-melt dose comprising medicament, superdisintegrant, dispersing agent, distributing agent and binder
Inventor: KOTHARI SANJEEV H
IPC: A61K47/38
Filed: 2000-06-20
Abstract: There is provided granules for the production of flash-melt pharmaceutical oral dosage forms. In addition to one or more medicaments, the granules are composed of an excipient combination consisting of a super-disintegrant, a dispersing agent, a distributing agent, and a binder and may also include other conventional ingredients such as sweetening and flavouring agents. The subject granules are advantageous in that they are stable and can be prepared without the aid of solvents and without the need for special environments or handling. Dosage forms, especially tablets, prepared therefrom on conventional equipment disintegrate in the mouth in under twenty five seconds.
Patent NZ-514140-A (NZ)
Title: Chlamydia antigens and corresponding DNA fragments and uses thereof
Inventor: MURDIN ANDREW D
IPC: C07K19/00
Filed: 2000-03-09
Abstract: The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by strain of  Chlamydia , specifically  C .  pneumoniae , employing a vector containing a nucleotide sequence encoding a 60kDa cysteine-rich membrane protein of a strain of  Chlamydia pneumoniae  and a promoter to effect expression of the 60kDa cysteine-rich membrane protein gene in the host. Modifications are possible within the scope of this invention.
Patent NZ-516440-A (NZ)
Title: Search system
Inventor: JIANG JASON
IPC: G06F17/30
Filed: 2000-06-30
Abstract: A search engine and system for data, such as Internet web pages, including a query analyser for processing a query to assign respective weights to terms of the query and to generate a query vector including the weights, and an index network responsive to the query vector to output at least one index to data in response to the query. The index network is a self-generating neural network built using training examples derived from a feature extractor. The feature extractor is used during both the search and training phase. A clusterer is used to group search results.
Patent NZ-516556-A (NZ)
Title: Displaying medical images and effects of disease and/or drugs
Inventor: RICHARD GREGORY WILLIAM
IPC: G16H70/40
Filed: 2000-07-21
Abstract: A processing system for demonstrating the effects of illnesses and treatments on a living being includes a store for storing image data, an input for receiving commands from a user, a display and a processor. The system is adapted to display an image sequence showing the effects of diseases, drugs, surgery and other treatments thereon on a living being from stored image data. The image sequence includes a number of images generated based on a wire image sequence of the living body. In its preferred arrangement, the images are in a three dimensional format, preferably animated, and may be viewed from any desired angle, direction, cross-section or other viewpoint. The system may be implemented on a single computer (3), or utilizing modems and a communications carrier (2) may be embodied on a central database (1) having a plurality of remote terminals (3) connected thereto.
Patent NZ-521162-A (NZ)
Title: Pyridazinyl phenyl hydrazones useful against congestive heart failure
Inventor: PYSTYNEN JARMO
IPC: A61P9/04
Filed: 2001-03-12
Abstract: Compounds of formula (I) are described wherein R1-R9 are described in the specification. Compounds of this formula are used in pharmaceutical compositions.
Patent NZ-524047-A (NZ)
Title: Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
Inventor: D AUGUSTINE MERIDA A
IPC: A61F13/20
Filed: 2001-06-25
Abstract: Disclosed is a use of a composition comprising a pharmaceutical agent, a pharmaceutically acceptable non-toxic lipophilic or hydrophilic carrier, mucoadhesive agent and a penetration enhancer, for the manufacture of a medicated device for delivering a therapeutically effective dose of the pharmaceutical agent to the vaginal epithelium or mucosa or transvaginally to the uterus, cervix or uterine muscle of a human female for the treatment of vaginal or uterine fungal, bacterial, viral or parasitic infection, wherein the pharmaceutical agent is selected from the group consisting of an antifungal agent, parasiticidal agent, antibacterial agent, antiviral agent and trichomonicide, and wherein the device, when inserted intravaginally, maintains contact with the vaginal epithelium and continuously releases the pharmaceutical agent without previous wetting, pressure or other mechanical action.
Patent NZ-527572-A (NZ)
Title: 3-(4-amidopyrrol-2-ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors
Inventor: LIANG CONGXIN
IPC: A61P35/00
Filed: 2002-02-15
Abstract: Disclosed are compounds of formula (I), wherein: R1 is H, halo, alkyl, haloalkyl, cycloalkyl, heteroalicyclic, hydroxy, alkoxy, -C(O)R8, -NR9R10 or -C(O)NR12R13, R2 is H, halo, alkyl, trihalomethyl, hydroxy, alkoxy, cyano, -NR9R10, -NR9C(O)R10, -C(O)R8, -S(O)2NR9R10 or - SO2R14, R3, R4 and R5 are independently H or alkylo, Z is aryl, heteroaryl, heterocycle, or -NR15R16 wherein R15 and R16 are independently H or alkyl, or R15 and R16 together form a heterocycloamino group, R6 is H or alkyl, R7 is H, alkyl, aryl, heteroaryl, or -C(O)R17, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the modulation of the catalytic activity of a protein kinase.
Patent NZ-529911-A (NZ)
Title: Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
Inventor: AVERBACK PAUL A
IPC: A61P31/04
Filed: 2002-05-24
Abstract: Disclosed is an amino acid consisting of a sequence selected from any one of SEQ ID Nos. 10 to 51 as shown in the specification. Peptides of the type disclosed are functional fragments of AD7C-NTP (neural thread protein) useful for treating benign and malignant tumors as well as hyperplasia, hypertrophy or tissue overgrowth and inflammatory disorders.
Patent NZ-533076-A (NZ)
Title: Device attached between a tractor and a grass mowing machine which permits the mowing machine to be trailed rather than attach directly to the rear of the tractor
Inventor: JAMES MCEWEN
Filed: 2004-05-24
Abstract: A device for introduction between a commercial mowing machine B and tractor A which allows the mowing machine B to be trailed behind the tractor A. The device includes means for lifting the mowing machine B clear of the ground and carrying the majority of the weight of the mowing machine when it is lifted clear of the ground, wheels to enable transportation of the mowing machine B when it is not in operation, means for adjusting a centre of gravity such that a downward force is applied to a towing attachment when the mowing machine B is raised for transportation and means to position the mowing machine B to allow easy access to the underside of the machine B.
Patent NZ-534288-A (NZ)
Title: Goat serum and compositions thereof
Inventor: HEENEY JONATHAN
IPC: C07K16/00
Filed: 2003-01-28
Abstract: Disclosed is the use of a serum composition obtained from a goat in the preparation of a medicament for the treatment of motor neurone disease, chronic inflammatory condition of the nervous system or lymphoma. The composition may be obtained from the serum of a goat after challenge with human cell line membrane antigens, human white blood cells or HIV lysate, and may optionally contain anti-HLA antibody.
Patent NZ-535206-A (NZ)
Title: Self-propelled crew conveyance for orchard canopy management
Inventor: MARSHALL JOHN
Filed: 2004-09-10
Abstract: A three-wheeled, self-propelled vehicle for conveying up to five workers while they perform orchard maintenance tasks is disclosed. The steering, speed, and forward-reverse direction functions are all controlled by foot so that an operator's hands are left free to perform other tasks. The driver may sit behind the workers, allowing supervision of their work quality and output. The seat arrangement may also be modified to adjust the vehicle width to allow for different orchard row spacings.
Patent NZ-535551-A (NZ)
Title: Slide rule for calculating dates
Inventor: MASSANG JAIME RICARDO
Filed: 2004-09-24
Abstract: A date calculator for calculating dates significant to the processing of applications for protection of intellectual property is disclosed. The calculator 1 is in the form of a slide rule, having an elongate member with a display showing the significant dates aligned in a number of columns 4. A sliding portion 3 has a column displaying a list of significant events 6 in the application processing process and one or more windows 5 through which a column of dates may be viewed. The list of events aligns with the column of dates to allow calculation of when events are due to occur in the application process. Shoulders 2 at each end of the elongate member limit the movement of the sliding window.
Patent NZ-537753-A (NZ)
Title: Combination of ZD6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer
Inventor: WEDGE STEPHEN ROBERT
IPC: A61K31/517
Filed: 2003-08-05
Abstract: Disclosed is the use of ZD6474 or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in the production of an anti-cancer effect in a warm-blooded animal such as a human which is being treated with ionising radiation before, after or at the same time as the administration of a medicament comprising ZD6474, wherein the effect of such a combination treatment is synergistic.
Patent NZ-539749-A (NZ)
Title: Immediate release tablets of thrombin inhibitors i.e. melagatran and inogatran comprsing strach and cellulose as fillers
Inventor: FORSMAN SIGBRIT
IPC: A61K9/14
Filed: 1999-08-27
Abstract: An oral immediate release pharmaceutical composition in solid form comprising: (a) a low molecular weight peptide thrombin inhibitor, having pH dependent solubility and a particle size of less than 300 micrometers selected from inogatran, melagatran and glycine, N-[1-cyclohexyl-2-[2-[[[[4-[hydroxyimino)aminomethyl]-phenyl]methyl]amino]-carbonyl]-1-azetidinyl]-2-oxothyl]-, ethyl ester, [S-(R*,S*)]-), and (b) a filler or a combination of filler, not including sodium starch glycollate, selected from the group consisting of microcrystalline cellulose, microfine cellulose, cross-linked sodium carboxymethyl cellulose, cross-linked hydroxypropyl cellulose, pregelatinised starch, maize starch, potato starch, rice starch, wheat starch, wheat starch and mixtures thereof, in an amount higher than 35% w/w of the pharmaceutical composition. Also described is the use of an oral pharmaceutical composition in the manufacture of an oral formulation for the prophylaxis and/or treatment of thromboembolism.
Patent NZ-543576-A (NZ)
Title: Beverage machine for preparing a hot beverage by brewing and extracting a substance received in a cartridge
Inventor: SCHIFFERLE RENE
IPC: A47J31/40
Filed: 2005-11-15
Abstract: In a coffee (or tea or.) brewing machine a sealed cartridge 4 containing the coffee material to be brewed is placed into a brewing chamber 2 and sealed into the chamber by closing the cover 3. As the cover is closed the piercing element 20 pierces the top seal 4a of the cartridge to permit water from the water supply 6 and boiler 7 to enter the cartridge, and the top tip portion 28a of the bottom piercing element 15 pierces or weakens a spot 4b in the bottom wall of the cartridge. As boiling water is injected into the cartridge through the inlet 21 the cartridge is pressurized which forces the central tip portion 28b of the bottom piercing element to pierce the bottom wall of the cartridge to allow coffee liquid to flow through apertures 29 to the delivery spout 18. The progressive piercing or weakening and piercing permits a more controlled piercing process of the bottom of the cartridge assuring a better diffusion of water through the grounds in the cartridge, and ensuring that the bottom of the cartridge is opened at a well defined location and at a well defined stage of the water injection process.
Patent NZ-547240-A (NZ)
Title: Hybrid power system for continuous reliable power at locations including remote locations
Inventor: BRONICKI LUCIEN Y
IPC: B25B/
Filed: 2004-11-17
Abstract: A method for producing continuous power using a hybrid power generating system and a hybrid power generating system is disclosed. The hybrid power generating system comprises: a) a primary power unit that produces electric power that is supplied to a load; and b) a secondary power unit in the form of a closed cycle vapour turbine (CCVT) system, which is heated by the rejected heat of the primary power unit and produces electric power that is supplied to a load. The working fluid in the vaporizer of the (CCVT) is heated by the heat rejected by the primary power unit and the secondary power unit is capable of producing only approximately 5 to 15% of the electric power that is produced by the primary power unit. The CCVT includes a burner that combusts the same fuel as supplied to the primary power unit and supplies sufficient heat so that the CCVT continues to produce approximately 5 to 15% of power produced by the primary power unit upon a power outage of the primary power unit.
Patent NZ-549258-A (NZ)
Title: Control method for process of removing permanganate reducing compounds from methanol carbonylation process
Inventor: TRUEBA DAVID A
IPC: C07C51/44
Filed: 2005-02-24
Abstract: Disclosed is a method of controlling a separation process for removing permanganate reducing compounds from a process stream in the methanol carbonylation process for making acetic acid, where the method includes the steps of measuring the density of a stream containing acetaldehyde and methyl iodide, optionally calculating the relative concentrations of acetaldehyde and methyl iodide in the stream, and adjusting distillation or extraction process parameters based on the measured density or one or more relative concentrations calculated therefrom. Particularly disclosed is a process for separating acetaldehyde from methyl iodide by distillation, comprising the steps of: distilling a mixture comprising methyl iodide and acetaldehyde in a distillation apparatus to produce an overhead and a residuum; measuring the density of said overhead; determining the relative concentration of the methyl iodide, the acetaldehyde, or both in the overhead from the measured density; and adjusting at least one process variable associated with said distillation apparatus in response to said measured density or a relative concentration calculated therefrom, said process variable being selected from the group consisting of heating rate, column pressure, feed composition, reflux composition and reflux ratio. Further disclosed is a process for producing acetic acid comprising the steps of: reacting methanol with carbon monoxide in a reaction medium comprising water, and methyl iodide in the presence of a catalyst; performing a liquid-vapor separation of said reaction medium to provide a vapor phase comprising acetic acid, methyl iodide, acetaldehyde and water and a liquid phase distilling said vapor phase in a distillation apparatus to produce a purified acetic acid product and at least a first overhead comprising acetaldehyde and methyl iodide; condensing said first overhead; extracting said first overhead with water to produce a raffinate comprising methyl iodide and an aqueous extract; measuring the density of at least one stream selected from the group consisting of said first overhead, said raffinate and said aqueous extract; determining the relative concentration of the methyl iodide, the acetaldehyde, or both in at least one of said first overhead, said raffinate and said aqueous extract from the measured density; and adjusting at least one process control parameter associated with either the distillation of said vapor phase or the extraction of said first overhead in response to said relative concentration.
Patent NZ-555679-A (NZ)
Title: A system for reading and authenticating a composite image in a sheeting
Inventor: KENNER MARTIN A
IPC: G07D7/12
Filed: 2005-10-27
Abstract: A system for reading and authenticating a composite image in a sheeting is disclosed. The system comprises a sheeting and a reader. The sheeting includes a composite image that appears to the unaided eye to be floating above or below the sheeting or both. The reader includes a computer for comparing the first image and the second image of the sheeting and for comparing the first image and second image of the composite image floating above or below the sheeting or both to calculate the perceived distance between the sheeting and the composite image floating above or below the sheeting or both. The reader further includes a first camera to capture a first image of the sheeting and a first image of the composite image floating above or below the sheeting or both; a second camera to capture a second image of the sheeting and a second image of the composite image floating above or below the sheeting or both or alternatively the reader can include a camera moveable between a first position and a second position. In the first position the camera captures a first image of the sheeting and a first image of the composite image floating above or below the sheeting or both and in the second position the camera captures a second image of the sheeting and a second image of the composite image floating above or below the sheeting or both and the computer as described above. Or alternatively the reader can comprise the computer as described above, a camera; and a sheeting holder moveable between a first position and a second position. The sheeting is positioned on the sheeting holder. In the first position the camera captures a first image of the sheeting and a first image of the composite image floating above or below the sheeting or both and in the second position the camera captures a second image of the sheeting and a second image of the composite image floating above or below the sheeting or both.
Patent NZ-555857-A (NZ)
Title: Level sensor extracting its operating power from an indicating instrument
Inventor: AGUGLIA JORGE MIGUEL
IPC: G01F23/00
Filed: 2005-07-18
Abstract: Sensor (5) of liquid levels in a tank comprises a probe (10) adapted to measure a liquid level in a tank and to generate first electric signals dependent on the level and an electronic device (20) connected to the probe and adapted to receive the first electric signals and to generate second electric signals adapted to be managed by an indicator instrument (14) connectable to the electronic device and adapted to display an information corresponding to the level. The electronic device comprises a power extracting circuit (29) adapted to extract, from the second electric signals, power signals for providing power supply to the sensor.
Patent NZ-564758-A (NZ)
Title: G-protein coupled receptor agonists
Inventor: BARBA OSCAR
IPC: A61K31/4545
Filed: 2006-06-30
Abstract: Disclosed are compounds of formula (I), wherein Z is optionally substituted aryl, heteroaryl, -C1-4alkylaryl or -C1-4alkylheteroaryl, one of A1 and A2 is N or N+-O-, and the other is CH, C(OH) or N, B is C1-4alkylene or C1-4alkenylene, G is substituted CHR2 or NR1 and the remaining substituents are as defined in the specification. Particularly preferred are compounds of formula (Ib). Also disclosed are intermediates (12) useful in the preparation of the compounds of formula (I), which are GPCR agonists useful in the treatment of metabolic syndrome (syndrome X), impaired glucose tolerance, hyperlipidemia, hypertriglyceridemla, hypercholesterolemia, low HDL levels or hypertension.