baber/WOPTO huggingface dataset:
Patent IE-38646-L (IE)
Title: Morpholine and oxazine derivatives.
IPC: C07D267/10
Filed: 1973-12-17
Abstract: 1394001 2 - (Morpholino or homomorpholino) - 1 - (3 - trifluoromethylphenyl) propanes PFIZER Ltd 19 Dec 1973 [22 Dec 1972] 59360/72 Heading C2C Novel compounds of the Formula I in which R is hydrogen or halogen; R<SP>1</SP> is alkyl; R<SP>3</SP> and R<SP>4</SP> each are hydrogen, alkyl or phenyl; R<SP>5</SP> is hydrogen or alkyl and n is 1 or 2 wherein alkyl groups are C 1-4 groups and non-toxic acid addition salts thereof may be prepared by (1) reacting a compound II with an appropriately substituted morpholine or homomorpholine followed by reduction of the intermediate ethylene derivative; (2) reacting a compound VI wherein X is halogen or an alkyl or arylsulphonyloxy group with the morpholine or homomorpholine; (3) reacting a compound VIII with a 2,2<SP>1</SP>-dichlorodiethyl ether or a substituted derivative thereof ClCHR<SP>5</SP>CHR<SP>4</SP>OCHR<SP>3</SP>CH 2 Cl; (4) reacting a compound of the Formula XVIII with a chloracetylchloride ClCHR 3 COCl, to yield a compound XIX followed by dehydrohalogenation to cyclize to the compound XX followed by reduction of the keto group; (5) reacting a compound of the Formula XVIII with an epoxide X followed by dehydration of the product of the Formula XVI or other equivalent processes. 1 - (3 - Trifluoromethylphenyl) - 2 - p - toluene sulphonyloxypropane may be prepared by esterification of 1 - (3 - trifluoromethylphenyl)- propan-2-ol with p-toluenesulphonylchloride. Pharmaceutical compositions of the compounds I alone or with the usual excipients may be administered orally or parenterally to reduce the appetite.
[GB1394001A]
Patent IE-892367-L (IE)
Title: Selectively o-acylated glycosaminoglycans, their preparation¹and pharmaceutical compositions containing them
IPC: A61K31/7024
Filed: 1989-07-21
Abstract: The glycosaminoglycans of the invention are selectively O-acylated in a controllable manner on their free -OH groups, the carboxylic or amino functional groups being unaltered. These compounds have a pharmacological activity of very long duration.
Patent IE-812386-L (IE)
Title: Powder for dry sensitization for electroless plating.
IPC: H05K3/18
Filed: 1981-10-12
Abstract: PCT No. PCT/DK81/00087 Sec. 371 Date Jun. 4, 1982 Sec. 102(e) Date Jun. 4, 1982 PCT Filed Oct. 9, 1981 PCT Pub. No. WO82/01382 PCT Pub. Date Apr. 29, 1982.This invention relates to a powder for use in dry sensitization for electroless plating, the powder comprising a plastics base material which is a mixture of hydrophobic and hydrophilic plastics materials to which has been added sensitizing particles.
[US4518738A]
Patent IE-40126-L (IE)
Title: Electric storage cell
IPC: H01M50/491
Filed: 1974-11-20
Abstract: 1484158 Battery separators COMPAGNIE EUROPEENNE D'ACCUMULATEURS 15 Nov 1974 [21 Nov 1973] 49603/74 Heading H1B A separator for a lead-acid accumulator plate 1 comprises 2 microporous, insulating plates 2, 3 connected together wholly or partly around their edges by means of flat connecting members 5, 6. The members 5, 6 are preferably of a polyethylene copolymer to which synthetic acrylic rubber is added, the material being applied around the edges of plates 2, 3 at an elevated temperature and being allowed to solidify and become rigid on cooling. The sheets 2, 3 may be of a phenolic resin containing polyester, or they may be of P.V.C. foam and have pores of a radius in the range 1-7 Á and a porosity in the range 75- 80%.
[GB1484158A]
Patent IE-872440-L (IE)
Title: 13-deoxy-23-oxo (keto) and 23-imino derivatives of 13-deoxy¹c-076-aglycone compounds
IPC: A23K20/195
Filed: 1987-09-11
Abstract: The present invention relates to novel 23-oxo (keto) and 23-imino derivatives of C-076 wherein the C-076 compounds are not substituted at the 13-position. The C-076 compounds (collectively) are isolates from the fermentation broth of Streptomyces avermitilis. The present 23-oxo compounds are prepared by selectively oxidizing suitably protected 13-deoxy C-076 aglycone compounds by using oxidizing agents. Subsequently, the 23-oxo compounds are converted to the 23-imino compounds. These novel compounds have potent anthelmintic, insecticidal, ectoparasiticidal, nematicidal and acaricidal activity. Compositions containing these 23-oxo and 23-imino derivatives of 13-deoxy C-076 aglycones also are described herein.
[EP0260537A1]
Patent IE-843005-L (IE)
Title: Polyethylenimine bound chromatographic packing
IPC: B01J20/32
Filed: 1984-11-23
Abstract: The reaction product of silica gel or controlled pore glass and polyethyleniminopropyl trimethoxy silane suitable for use as chromatographic column packing.
Patent NO-752141-L (NO)
Inventor: PLOWS G S
IPC: B29C41/12
Filed: 1975-06-16
Abstract: Apparat til dannelse av en ensartet film på en plan bærer.
Patent NO-813684-L (NO)
Inventor: ASPEREN PIETER JAN VAN
IPC: C08L51/00
Filed: 1981-10-30
Abstract: The invention relates to a polymer composition based on a polycarbonate and a graft copolymer of a vinylaromatic compound and an unsaturated nitril compound on a rubber. This composition is characterized in that it comprises:  a) one or ore polycarbonates, and b) a graft copolymer obtained by polymerizing, in a first step, a mixture of 10-30 % by weight of acrylonitrile, 10-75% by weight of styrene and 0-70% by weight of  alpha -methylstyrene in the presence of a latex of a rubbery polymer and by polymerizing, in a second step, in the presence of the latex produced in the first step, a mixture of 10-30% by weight of acrylonitrile, 0-50% by weight of styrene and 40-90% by weight of  alpha -methylstyrene.
Patent NO-842827-L (NO)
Inventor: PHILLIPS ROGER C
IPC: C12Q1/00
Filed: 1984-07-11
Abstract: A disposable test strip device for detecting and measuring ethanol in aqueous solutions is disclosed. The test strip includes an inert support pad that contains a stabilized dry form of the enzyme alcohol oxidase, a material having peroxidative activity and an oxygen acceptor that reacts with hydrogen peroxide to give a compound of changed color. The use of this strip to determine ethanol levels colorimetrically is also disclosed.
Patent NO-852830-L (NO)
Inventor: RUCHEL PETER
IPC: F16D23/04
Filed: 1985-07-15
Abstract: A brass alloy, a process for the production of a brass material or semi-finished brass product from that type of a brass alloy, as well as to the utilization of the brass material; in essence, the brass alloy for semi-finished products and semi-finished articles, which in addition to a good workability must possess a high resistance to wear, especially when employed for synchronous rings. The foregoing is possible through the intermediary of entirely determined contents of chromium and/or zircon in the previously described brass alloy. The chromium contents hereby vary, on the one hand, in dependence upon the silicon contents, and on the other hand, however, also to a lesser measure upon the remaining alloy components within the range of between 0.01 to 0.15% by weight, and preferably between 0.05 and 0.1% by weight.
Patent NO-853537-L (NO)
Inventor: GROSS PAUL
IPC: A61K8/81
Filed: 1985-09-10
Abstract: Composition for setting the hairdo and grooming of the hair on the basis of a synergistic combination of (a) 0.1 to 10.0% by weight of a quaternized copolymerisate consisting of vinyl pyrrolidon and dimethyl aminoethyl methacrylate (80:20) and (b) 0.1 to 5.0% by weight tetraoxyethylene lauryl ether. By corresponding tests it is shown that other fatty alcohol polyoxyethylene ether than tetraoxyethylene lauryl ether with the component (a) do not show a synerigistic effect reinforcement.
Patent NO-860316-L (NO)
Inventor: HERBST THOMAS
IPC: E21D21/00
Filed: 1986-01-29
Abstract: An anchoring apparatus for insertion into a borehole in a rock stratum for supporting the rock surface or wall, such as in a rock tunnel or rock excavation, includes a tension member in the form of an axially elongated steel rod with force transmission ribs on its outer surface and an anchoring element, such an anchoring nut, engageable with the rod. The anchoring element has an inside surface with inwardly extending projections and the adjacent flanks on the projections form grooves within which the force transmission ribs engage. The anchoring element is formed of a higher strength material than the rod. When a predetermined axially extending tension force acting on the rod is exceeded, relative movement takes place between the anchoring element and the rod. The flanks on the projections on the anchoring element in contact with the ribs on the rod shear off a portion of the ribs contacted. Accordingly, while the predetermined force is exceeded, the shearing action proceeds and affords a sliding anchoring effect between the rod and the anchoring element.
Patent NO-864950-L (NO)
Inventor: STEER PETER LESLIE
IPC: A61F5/448
Filed: 1986-12-09
Abstract: An ostomy appliance intended for attachment to a peristomal area of a wearer includes a pad (20) of medical-grade skin-attachable adhesive material, a first coupling element (12) secured thereto, the element having a radially outwardly extending flange (30) attached to a surface of the pad and an upstanding rib (32) of closed loop form constructed to couple with a counterpart (second) coupling element (56) on a bag or pouch (64). An inner chute member (24) is located radially within and adjacent to the first coupling element, the chute member having a substantially cylindrical wall (72) covering the whole of the radially inner surface of the first coupling element. At one of its ends, the chute has a radially outwardly extending flange (70) positioned so that it traps the chute member in position when the two coupling elements are coupled toqether.
Patent NO-881353-L (NO)
Inventor: RIBAUDO NICKOLAS
IPC: B66B13/00
Filed: 1988-03-25
Abstract: A hydraulic door opening or closing device comprises a hydraulic fluid pump motor (7) having two ports connected to each end of integral dual manifold (8, 9) and operating cylinder apparatus (10) by way of two branch fluid lines (11, 12). One branch line is fluidly connected to a particular end of the operating cylinder by way of a directional flow valve (17, 18). The other branch line to the same end of the cylinder is fluidly connected to the cylinder by way of an associated manifold (8, 9). Fluid communication with the cylinder through the manifold (8, 9) is accomplished by providing a plurality of valved openings (21-30) linearly disposed along the end of the cylinder between the manifold (8, 9) and the cylinder (10). As a piston (14) of the operating cylinder (10) passes these openings, a door coupled to the piston (14) is automatically slowed as fluid on the drive side of the piston is returned through the openings to the hydraulic fluid pump (7). A simplified control circuit coupled to the device provides three modes of operation, an opening mode, a closing mode and a reversing mode from door opening to door closing.
Patent NO-882353-L (NO)
Inventor: SCHEROWSKY GUENTHER
IPC: G02F1/139
Filed: 1988-05-27
Abstract: Optically active oxirane-2-carboxylic esters with a mesogenic moiety are suitable for use as dopants in liquid crystal mixtures. They lead to liquid-crystalline ferroelectric phases having short response times and to electroclinic phases having large electroclinic coefficients. A further advantage is that they induce a helix of very small pitch, so that they are also suitable for helix compensation in LC mixtures.
Patent NO-901857-L (NO)
Inventor: BUSCALL RICHARD
IPC: C01G9/02
Filed: 1990-04-26
Abstract: A method for the preparation of colloidally stable particles of inorganic solid at high concentration which method comprises at least the step of precipitating from an aqueous medium the particles of the inorganic solid in the presence of a copolymer which comprises repeating units derived from:   Component A: a hydrophilic oligomer or polymer bearing an addition-polymerisable olefinically-unsaturated group; Component B: an olefinically-unsaturated compound capable of copolymerising with Component A and bearing a mineral acid group or a dicarboxylic acid group, or a carboxylic acid and a further group capable of hydrogen-bonding. n
Patent NO-910019-L (NO)
Inventor: MEYER JEAN-LUC
IPC: B22D11/04
Filed: 1991-01-03
Abstract: The invention relates to a continuous casting method for producing thixotropic metallic alloys containing degenerated dendrites. It consists of casting the liquid metal in a movable occluded mould consisting of a hot upstream zone produced from insulating material and a cooled downstream zone in which the metal solidifies, while carrying out by means of a sliding magnetic field, obtained by a series of polyphase inductors, an electromagnetic agitation which causes the dendrites formed in the cold zone to pass into the hot zone where they change to nodules by superficial refusion. This invention is particularly applicable to the production of aluminum plates or bars having thixotropic properties.
Patent NO-922025-L (NO)
Inventor: GUTHRIE JAMES LEVERETTE
IPC: A61L31/06
Filed: 1992-05-22
Abstract: A degradable article comprising a polyurethane polymer gel or foam whose polymer structure contains hydrolytically unstable ester linkages and various additives. The article can be constructed so that some of the additives are released from the article at a sustained rate. In a preferred embodiment the additives are sensory stimulants for marine or aquatic organisms and the article is used as bait for those organisms.
Patent NO-940888-L (NO)
Inventor: HOMANN WALTER KLEINE
IPC: C08G63/52
Filed: 1994-03-11
Abstract: The object is to prepare a high-molecular-weight polyester in such a way that it is possible to make even relatively small amounts of very high molecular weight available in an advantageous manner. This is achieved by preparing a polyester containing an alkenediol by continuing the polycondensation step to a viscosity number of 50 - 140 cm<3>/g and treating the resultant polyester with from 0.001 to 8 % by weight of a free-radical former which decomposes at temperatures in the range from 130 to 350 @C with a half value period of from 5 s to 120 min, and subsequently continuing the polymerisation to the requisite viscosity number. The process according to the invention allows high-molecular-weight polyesters having the desired property profile to be obtained.
Patent NO-942261-L (NO)
Inventor: MUSTAJARVI HANNU
IPC: B65G33/04
Filed: 1994-06-15
Abstract: The invention relates to an apparatus intended for transferring bulk in a transfer step substantially in a single transfer direction (s) from a first point (I) to a second point (II). The bulk (1) to be transferred includes a transverse and rigid transmitting surface (2) and a connecting surface (3), providing a connection with transmitting surface (2) substantially through the interior of bulk (1), and the bulk is transferred or carried by means of a transfer mechanism (4), operating between first and second (I, II) points and including a contact element (5), rotating around its longitudinal axis (a) and provided with a first component (5a) located at a constant distance from its longitudinal axis (a), and a bearing surface (6), located in its longitudinal direction substantially parallel to transfer direction (s) and bearing said bulk (1) during the course of its transfer. Upon carrying bulk (1) by means of transfer mechanism (4) in accordance with the invention, its transmitting surface (2) in communication with said first component (5a) of contact element (5) in a manner that said first component (5a) extends through said connecting surface (3) substantially into the interior of bulk (1).
Patent NO-943898-L (NO)
Title: 3,4-dihydro-2H-1,2,4-benzotiadiazin-1,1-dioksyd-3-karboksylsyrederivater, deres fremstilling samt medikamentene inneholdende derivatene
Inventor: ALOUP JEAN-CLAUDE
IPC: C07D417/04
Filed: 1994-10-14
Abstract: Forbindelser med den generelle formel: der R betyr (a) et hydrogenatom, (b) en alkylrest, (c) en allylrest, (d) en fenylrest, (e) en 2- eller 3-pyrldylalkylrest, (f) en 2-klnolylalkylrest. (g) en (|) naftylalkylrest, (h) en cykloalkylalkylrest, (1) en 2H-3-nafto[1.8-cd]lsotlazol- 2-yl-l,l-dloksyd)alkylrest, en (5.6-dihydro-lH,4H-l,2,5-tladlazol[4,3(2-lj]- kinolyl-2,2-dioksyd)alkylrest, (k) en -alk-CO-R5-rest, (1) en -alk-R6-R7-rest, (m) en 4-fenylplperazlnylalkylrest der fenylkjernen eventuelt er substituert med en eller flere substltuenter valgt blant halogenatoroer og alkyl- eller alkoksyrester, (n) en 10-fenotlazinylalkylrest, (o) en (10-alkyl-2-fenotlazinyl)alkylrest, (p) en 3-indolylalkylrest, (q) en fenyl- alkyloksyrest, (r) en l-fenylalkyl-4-piperidylrest, (s) en 2-tlenylalkylrest eller (t) en fenylalkylrest der fenyl eventuelt er substituert med en eller flere substltuenter valgt blant halogenatomer og restene alkyl, alkoksy, poly- fluoralkyl, amino, nitro, cynno, fenyl, vinyl, polyfluoralkoksy. alkoksykarbonyl, karboksy, fenylalkyloksy, fenyl- alkyl, benzoylamlno, fcnylkorbonyl og fenoksy hvis fenylkjerne eventuelt er substituert med en eller flere substl- tuenter valgt blant halogenatomer og restene alkyl, alkoksy eller polyfluoralkyl, R! betyr en rest karboksy, alkoksykarbonyl, tetrazolyl, -CO-NH2, -CO-NH-alk. -C0-N(alk)2, -CO-NHOH, -CO-N(alk)OH, -CO-NH-O-RS, -CO-N(alk)-ORg eller en gruppe som kan omdannes til en karboksyrest in vlvo, R2> R3 °8 84 som er like eller forskjellige, hver betyr et hydrogen- eller halogenatom eller en alkyl- eller alkoksyrest, RS betyr en hydroksy-, alkoksy-, fenyl- eller -NRgRjQ-rest, R0 betyr et oksygen-, svovel- eller nitrogenatom eller en rest SO, S02 ejler -N-alk, Ry betyr en rest alkyl-, fenylalkyl- eller fenylrest eventuelt substituert med et eller flere halogenatomer, Rg betyr en alkyl- eller fenylalkylrest, Rg og R10 som er like eller forskjellige, betyr et hydrogenatom eller en alkyl- eller fenylrest, og alk betyr alkyl- eller alkylenrest, samt deres racemater, enantlomerer og salter, rapporteres å ha interessante farmakologiske egenskaper særlig som en KMDA- og/eller AMPA-reseptorantagonister. Forblndelsenes fremstilling beskrives.
Patent NO-944111-L (NO)
Inventor: NIES BERTHOLD WOLFGANG
IPC: C08B37/08
Filed: 1994-10-28
Abstract: The invention relates to a process for the preparation of aqueous solutions and gels of chitosan in which chitosan and an acidic chelating agent are dissolved in water. Such solutions can be drastically increased in viscosity or converted into highly viscous gels by adding salts of polyvalent metals and acids in which chitosan is only moderately soluble or is insoluble. From such solutions, salt-like chitosan/chelating agent adducts can be obtained by removing water or by precipitation using an organic solvent.
Patent NO-950605-L (NO)
Inventor: LUTZ JURG
IPC: A61K9/70
Filed: 1995-02-17
Abstract: A pharmaceutical formulation contg. at least one neutral or carboxylic acidic active ingredient with a dissociation constant below 10<-3>, mol. wt. below 500 and the following solubilities at room temp. (a) < 1% in water, (b) > 10% in 70% ethanol, (c) > 35% in CHCl3, (d) > 60% in pyridine comprises a transdermal therapeutic system contg. the active ingredient(s) in a galenic formulation which can take up sweat and from which the active ingredient(s) is/are constantly released over at least 24 hrs. by the action of the sweat water. Pref. the galenic formulation consists of 10-30 wt.% 5,6-benzo- alpha -pyron, 1-50 wt.% of a cremophor, 15-85 wt.% one or more polyalkylene glycols and opt. other emulsifiers, aids to consistency, aids to dissolution, solvents and/or higher 8-24C fatty alcohols.
Patent NO-950922-L (NO)
Title: Beta-laktamer
Inventor: BOHRINGER MARKUS
IPC: C07D463/16
Filed: 1995-03-10
Abstract: Det beskrives terapeutisk aktive 6-laktamer med den generelle formel I hvor Z er metylen, O eller S og R er H, eventuelt med karboksy, alkoksykarbonyl, karbamoyl, alkylkarbamoyl, fenylkarbamoyl eller hydroksyfenylkarbamoyl substituert (cyklo)alkyl, alkenylmetyl, alkenylmetoksykarbonyl, formyl, eventuelt med halo, cyan, karbamoyl alkoksy, karbamoylalkyltio eller karbamoylalkylamino substituert (cyklo)alkanoyl hhv. (cyklo)alkylsulfonyl, eventuelt med (cyklo)alkyl, alkoksykarbonylalkyl, benzyloksykar- , bonylalkyl eller karboksyalkyl substituert karbamoyl ; eller en ringstruktur med den generelle formel Q-X-CO- (al), Q-X-SO,- (a2), hvor Q er en 5- eller 6-leddet, eventuelt N-, S- og/eller Odig ring og X er en direkte binding eller en av gruppene -CH2-, -CH2CH2-, -CH=CH-, -NH-, -NHCH2-, -CH2NH-, -CH(NH2)-, -CH2CH2NH-, -C(=NOCH3)-, -OCH2- eller -SCH2-, og hvor A er alkyl, hydroksy alkyl, vinyl, cyanvinyl, alkoksy, eventuelt j fenylsubstituert (cyklo)alkanoyloksy hhv. (cyklo)alkyl- sulfonyloksy, eventuelt (cyklo)alkyl-substituert benzo- yloksy hhv. fenylsulfonyloksy, en rest -S-Het eller -S- CH2-Het, hvor Het er en 5- eller 6-leddet, N-, S- og/eller O-holdig heterocyklus, eller en rest CH2-L, hvor L er eventuelt fenylsubstituert (cyklo)- alkanoyloksy hhv. (cyklo)alkylsulfonyloksy, eventuelt (cyklo)alkyl-substituert benzoyloksy hhv. fenyl- sulfonyloksy, karbamoyloksy, (cyklo)alkoksykarbonyl, karboksy, azido, amino, (cyklo)alkanoylaraino, (cyklo)- alkylsulfonylami.no, (cyklo)alkylamino, di-(cyklo)alkyl- amino, en 5- eller 6-leddet, til et N-atom bundet ring eller en rest -S-Het eller -S-CH2-Het, hvor Het har ovennevnte betydning, og farmasøytisk akseptable, lett hydrolyserbare estere og salter av disse forbindelser.
Patent NO-951545-L (NO)
Inventor: BERNARDON JEAN-MICHEL
IPC: A61P29/00
Filed: 1995-04-24
Abstract: Bicyclic aromatic cpds. of formula (I), their salts and chiral analogues, are new. R1 = H, -CH3, -CH2-O-R3, -CH2-O-CO-R4, -O-R5, -O-(CH2)m-(CO)n-R6, -CO-R7, -CO-O-R8 or -S(O)p-R9, R2 = H, halo, lower alkyl, -NO2, -O-COR4, -OR9 or -N(R9)R10, Ar = a gp. of formula (a)-(e), X = -O-, -S(O)t or -NR9-, Y, Z = -O-, -S(O)t or -CR11R12, but are not both -O- or -S(O)t, m = 1-3, n = 0 or 1, p = 0, 1-3, t = 0, 1 or 2; R3, R5, R9, R10, R11, R12 = H or lower alkyl, R4 = lower alkyl, R5 = lower alkyl or heterocyclic radical, R7 = H, lower alkyl or -N(R')R", R', R" = H, lower alkyl, mono- or poly-hydroxyalkyl, aryl (opt. substd.) or an aminoacid, sugar or peptide residue, or R'+R" = heterocyclic gp., R8 = H, 1-20C alkyl, alkenyl, mono- or poly-hydroxyalkyl, aryl or aralkyl (opt. substd.) or an aminoacid, sugar or peptide residue.
Patent NO-952493-L (NO)
Title: Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene
Inventor: CAPET MARC
IPC: A61P43/00
Filed: 1995-06-21
Abstract: Forbindelser med formelen: der substituentene kan ha diverse betydninger, samt salter av disse forbindelser. Forbindelsene rapporteres å ha en interessante farmakologiske egenskaper, særlig i forbindelse med mangler forbundet med CCK og gastrin. Forbindelsenes fremstilling beskrives.
Patent NO-954908-L (NO)
Inventor: JACKSON WAYNE KEVIN
IPC: B41F19/02
Filed: 1995-12-04
Abstract: PCT No. PCT/AU94/00302 Sec. 371 Date Dec. 7, 1995 Sec. 102(e) Date Dec. 7, 1995 PCT Filed Jun. 6, 1994 PCT Pub. No. WO94/29119 PCT Pub. Date Dec. 22, 1994A security document or token such as a banknote (40) is provided which has a transparent portion (42) of plastics material which includes a security device (50). The region (44) surrounding the transparent portion (42) and preferably all the remaining part of the banknote (40) is printed with indicia. The security device (50) includes regions (52, 54, 56 and 58) of embossed lines extending at different angles to each other defining different shapes that are visible to a greater or lesser extent upon transmission and reflection of light as the note is tilted, rotated or viewed from different angles relative to a light source. The embossed lines in some of the regions (52 and 54) are finer than coarser and deeper and more widely spaced lines in the other regions (56 and 58). The coarser, deeper lines are of such a thickness and width to be detected by touch in addition to being visible by the naked eye. There is also provided a method of and apparatus for producing a banknote with a security device in accordance with the invention in which the transparent portion of the note is embossed during an intaglio printing process.