baber/WOPTO huggingface dataset:
Patent PT-1027053-E (PT)
Inventor: STRIKER GARY E
IPC: A61K31/70
Filed: 1998-10-09
Abstract: A method of preventing, reducing or reversing nephrotoxicity or renal dysfunction induced by administration of a cyclosporin or tacrolimus to a mammalian patient. The method comprises the co-administration to the patient, either before, together with or after cyclosporin or tacrolimus administration, of a pharmaceutical composition containing an effective amount of pentosan polysulfate (PPS) or a pharmaceutically acceptable salt thereof. The oral route of administration is preferred. The total daily dosage of PPS or PPS salt ranges from about 2 to about 50 mg/kg of patient body weight, or about 140 to about 3,500 mg per day in adult human patients. Also disclosed are a method of providing immunosuppressive therapy to a patient while avoiding cyclosporin or tacrolimus-induced nephrotoxicity, and combination pharmaceutical compositions to be used in such therapy.
Patent PT-1014314-E (PT)
Inventor: MEYER-STEFFENS KLAUS
IPC: G07F5/24
Filed: 1999-07-23
Abstract: The coin operated machine has a data base (12,14) in a microprocessor based system that handles national currency and Euro reference values. A comparison of values is made of coins held in a number of channels and is used in a conversion from national currency to Euro on a specific changeover day.
Patent PT-952148-E (PT)
Inventor: REITER LAWRENCE ALAN
IPC: A61P43/00
Filed: 1999-03-25
Abstract: A compound of the formula <CHEM> wherein Y is as defined above, useful in the treatment of arthritis or cancer and other diseases involving selective inhibition of matrix metalloproteinase-13.
Patent SG-19489-G (SG)
Title: Hot sprue sleeve valve assembly for an injection molding machine
IPC: B29C45/26
Filed: 1989-03-31
Abstract: A hot sprue valve assembly is provided for controlling flow of molten material into the mold cavity of an injection molding machine. The valve assembly is particularly designed for use with an injection molding machine for molding centrally apertured record discs, such as video information discs. The valve assembly includes a hot sprue bushing defining a heated flow path for passage of molten material toward a stationary dispersion head positioned centrally within the mold cavity. The dispersion head directs the molten material to flow in a generally radially outward direction with substantially uniform radial distribution into the mold cavity. A cylindrical sleeve valve is carried about the hot sprue bushing for reciprocal movement between an open position retracted from the mold cavity to permit flow of the molten material into the mold cavity, and a closed position projecting into the mold cavity in seated engagement with the dispersion head simultaneously to prevent flow of the molten material into the mold cavity and to mold a central aperture in the disc.
Patent SG-63382-G (SG)
Title: Ergoline l derivatives
IPC: C07D457/12
Filed: 1982-12-23
Abstract: The present invention provides compounds of formula I,    <IMAGE>  I wherein X is hydrogen, chlorine or bromine, R1 is methyl or ethyl, R2 is alkyl of 1 to 4 carbon atoms or allyl, R3 is CH2CN or a group -NR4R5, wherein R4 is hydrogen or alkyl of 1 to 4 carbon atoms, and R5 is alkanoyl of 1 to 5 carbon atoms, alkoxycarbonyl of 2 to 5 carbon atoms in the aggregate thereof, or mono-, di- or tri-haloalkoxycarbonyl of 3 to 5 carbon atoms, wherein the alkoxy group is substituted by halogen other than in the  alpha  position to the oxygen atom, or R5 is SO2R6, wherein R6 is alkyl of 1 to 4 carbon atoms, mono-, di- or tri-haloalkyl of 1 to 4 carbon atoms, phenyl, phenyl mono-substituted by halogen or alkoxy of 1 to 4 carbon atoms, or pyridyl, or R6 is a group NR7R8, wherein R7 and R8 are, independently, hydrogen or alkyl of 1 to 4 carbon atoms, or R7 and R8 together form -[CH2]n- or -[CH2]2-A-[CH2]2-, wherein n is a whole number from 3 to 7, and A is oxygen, sulphur, or nitrogen substituted by alkyl of 1 to 4 carbon atoms or phenyl which are useful as prolactin inhibitors, anti-parkinson agents, and anti-depressants.
Patent IE-45012-L (IE)
Title: 1,3,4- substituted pyrazoline derivatives
IPC: C07C49/84
Filed: 1977-01-06
Abstract: Compounds of the formula I <IMAGE> in which R1, R2, R3, R4 and X have the meaning defined in Patent Claim 1, are potent insecticides. They form the active substances of the novel insecticide preparations. They are prepared by reacting a compound of the formula II <IMAGE> with a compound of the formula III R1-N=C=X or with a compound of the formula <IMAGE> and, if appropriate, further reacting the resulting compound, in which R4 equals H, with an R4-halide.
[GB1570635A]
Patent IE-36133-L (IE)
Title: Closure for open-mouthed containers
IPC: B65D43/02
Filed: 1972-03-01
Abstract: A multi-part and distortable seal construction employing a biased center wall and sealing wall arrangement which, upon the application and release of pressure to a center-positioned plunger, distends and contracts the sealing wall portion thereof.
[US3756480A]
Patent IE-900262-L (IE)
Title: Cholesterol free salad dressing
IPC: A23L27/60
Filed: 1990-01-23
Abstract: A salad dressing of the mayonnaise type which is free of cholesterol and which exhibits excellent texture stability and mouthfeel. The amount of a protein source in the salad dressing is kept within a specified range, thereby limiting the amount of excess soluble protein available to denature and coagulate over time. The salad dressing maintains a desirable texture over extended periods of time; even at elevated temperatures.
[EP0380293A2]
Patent IE-810276-L (IE)
Title: Phenylpiperazine derivatives of oxadiazoles
IPC: C07D271/10
Filed: 1981-02-12
Abstract: Novel phenylpiperazinylpropanols of 1,3,4-oxadiazolylphenols and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful in the treatment of hypertonia.
Patent IE-820294-L (IE)
Title: Phenylpyrazone compounds, anti-inflammatory agents
IPC: A61P29/00
Filed: 1982-02-10
Abstract: Compounds of the formula <CHEM> where R is hydrogen, methyl, ethyl, propyl, 2-propenyl or 2-propynyl; an R min is hydrogen or fluoro possess glucocorticoid activity. The compounds where R is H are prepared by reacting a compound of the formula <CHEM> with (1H, 3H)-pyrimidine-2,4,5,6-tetrone, The compounds where R is other than hydrogen are prepared by reacting a compound where R is hydrogen with the appropriate alkylating agent.
[EP0058841A2]
Patent IE-40684-L (IE)
Title: Beverage carbonation
IPC: C01B32/50
Filed: 1975-02-24
Abstract: A rigid composite body containing crystalline molecular sieves and having liquid-permeable channels extending in a substantially vertical direction from one surface of said body to the interior thereof, preferably to an opposite surface, is charged with carbon dioxide so that when brought in contact with water or an aqueous beverage, the carbon dioxide will be released from the molecular sieve composite body to carbonate the solution. Such rigid, composite bodies are secured in a sealable, nestable, stackable container which provides a convenient and efficient means for dispensing such composite bodies in combination with a dry instant beverage mix for the preparation of carbonated beverages upon the addition of water.
[US4007134A]
Patent IE-790659-L (IE)
Title: Radiographic scanning agents.
IPC: A61K51/12
Filed: 1979-08-08
Abstract: Stable compositions, useful as technetium-99m-based scintigraphic agents, comprise gentisic acid or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (99mTcO4-) solution. The compositions are especially useful in combination with a phosphate or phosphonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent.
[US4233284A]
Patent IE-35929-L (IE)
Title: Plastics extrusion device.
IPC: B29C48/335
Filed: 1971-05-31
Abstract: 1320848 Automatic flow control SAINTGOBAIN INDUSTRIES 27 May 1971 [29 May 1970] 17563/71 Heading G3R The flow rate through a head of a multiple head plastics extruder is maintained equal with that through a reference head by utilizing any difference of flow to vary the temperature of the material flowing through the first head. In Fig. 3, dies 3 and 4 of a multiple head extruder are fed with molten polymer through ducts 5 and 6 from a supply 8. Strain gauge transducers 9 and 10 responsive to pressures upstream of the dies are arranged in a bridge circuit to produce a signal corresponding to any difference which is effective (a) to vary the supply of air to cooling ducts 16, (18) in one head and around duct 6 respectively and (b) to vary, through a PID regulator as a fine control, the interruption or magnitude of the energization of electric heaters 12 and 14 surrounding the head and die respectively until the pressures are equal and hence the flow through die 4 equals that through die 3.
[GB1320848A]
Patent IE-40985-L (IE)
Title: Insulin preparation.
IPC: A61K38/28
Filed: 1975-04-11
Abstract: 1492837 Sustained release insulin preparations HOECHST AG 7 April 1975 [13 April 1974 17 Dec 1974] 14079/75 Heading A5B Sustained release insulin preparations comprise (1) an aqueous medium, (2) a crystalline insulin, (3) dissolved des-phenylalanine <SP>B1</SP>-insulin of the same species and (4) 25 to 80 meg of zinc ion per 100 I.U. of insulin. The insulin and insulin derivative may be bovine or porcine. The zinc ion may be present as zinc chloride. The preparation may be made by mixing a suspension of insulin crystals containing zinc ion with a solution of des-phenylalanine-insulin also containing zinc ions and adjusting the pH to the required range.
[GB1492837A]
Patent FI-832520-L (FI)
Inventor: BUYNISKI JOSEPH P
IPC: A61K31/34
Filed: 1983-07-11
Abstract: Enhanced antiulcer activity is obtained in warm-blooded animals by the concomitant administration of the pepsin complexing agent, pepstatin, and an histamine H2-receptor antagonist of the formula <CHEM> wherein A, m, Z, n, R<1> and R<2> are as defined herein. Concomitant administration of the two entities reduces the amount of histamine H2-receptor antagonist necessary for treatment, thereby decreasing its side-effect liability.
Patent IE-39493-L (IE)
Title: Producing continuous yarns
IPC: D01D5/08
Filed: 1974-06-11
Abstract: Oriented continuous yarns are produced from synthetic thermoplastic by melt-spinning monofilaments which are taken off, cooled and wound up without the use of a godet roll at velocities of more than 2500 meters per minute. The monofilaments are combined in a bundle after the cooling zone which is then toted and moved through at least one vertically adjustable guide before it is wound up.
[US3996324A]
Patent IE-36743-L (IE)
Title: Isothiazolo pyrimidines
IPC: C07D513/04
Filed: 1972-10-06
Abstract: 1374690 Isoihiazolopyrimidines and their preparation FMC CORP 13 Oct 1972 [15 Oct 1971] 47241/72 Heading C2C Substituted isothiazolopyrimidines of the formula wherein R and R<SP>1</SP>, which may be the same or different, are straight or branched aliphatic hydrocarbon radicals having 1 to 4 carbon atoms, may be obtained by reacting (a) a 5 - alkyl - 3 - amino - 4 - cyanoisothiazole of the formula or (b) a 5 - alkyl - 3 - aminoisothiazole - 4- carboxamide of the formula in an acid medium with an acylating agent containing the radical R<SP>1</SP>-CO-. The acylating agent employed may be an acid chloride or anhydride and a suitable acid is sulphuric acid. The starting materials may be obtained by reaction of methyl mercaptan and hydrogen chloride with the appropriate alkanenitrile, followed by thiohydrolysis in pyridine with hydrogen sulphide to yield the methyl dithioalkanoate, reaction of the latter with malononitrile to form the sodium salt of a 2-cyano-3- mercapto-2-alkenenitrile which is subsequently reacted with monochloramine; the 3-amino-4- cyano-5-alkylisothiazole obtained may be hydrolysed with concentrated H 2 SO 4 to yield the corresponding amide derivative. The products possess herbicidal properties and may be formulated and applied in a conventional manner.
[GB1374690A]
Patent IE-36810-L (IE)
Title: Mixing liquids.
IPC: B01F23/47
Filed: 1972-10-27
Abstract: 1405020 Mixing an aerosol with a liquid BEKAERT SA NV 30 Oct 1972 [29 Oct 1971] 49976/72 Heading B1C In a method and apparatus for mixing a first liquid with a smaller quantity of a lower viscosity liquid additive, the first liquid is introduced into an enclosed mixing chamber e.g. duct 51 in mixing head 1, Figs 1, 2, and the additive is introduced into the first liquid together with a pressurised gas, in the form of an aerosol. In the apparatus, the gas is introduced by means of an inlet duct 32, 60 associated with means such as atomising valves 34-39 for introducing the liquid additive. In the particular method and apparatus, the gas in supply reservoir 30 is compressed air and also pressurises additive reservoirs 23, 24 containing the optional additives Freon (registered trade mark) and water, and cleaning solvent reservoir 40 which flushes out the mixing head after use. The first liquid is a combination of two components, separately agitated heated and stored before use in reservoirs 2, 3. These components such as a polyisocyanate and a polyhydroxyl compound, are fed to mixing head inlet valves 14, 15 along lines 7, 8 and may be recycled along lines 16, 17. The valves 14, 15 are adjustable needle valves, Fig 4, which may be switched on and off by compressed air in ducts 73 and 74, 83 and 84 which acts on flexible diaphragms 71, 72. After introduction of the first liquid, adjustable needle valve 33, Figs 1, 2 is opened by solenoid operated valve 63 controlling the flow of pressurised air to needle piston 61 and the compressed air flows from duct 60 into mixing duct. 51 to create turbulence in the liquids therein. One or more of valves 34-39 spaced around the axis of duct 60 is opened and the liquid additive forced in forms an aerosol with the air. After mixing-aided by impellers 53, 56-the mixture is ejected through duct 52 and valves 14, 15 34-39 are closed. Pressurised air from line 32 then cleans duct 51. Flushing solvent from reservoir 40 may then be introduced. The valves 34-39 may be of different flow rates but introduce additive at the same pressure so that used singly or in combination they can provide a selectively variable flow of additive and hence mixtures of variable proportions of constituents.
[GB1405020A]
Patent IE-40389-L (IE)
Title: 2,5- dideoxystreptamine and 6, 7- diaza-2,¹4-dihydroxybicyclo [3, 2, 1] octanes
IPC: C07D231/54
Filed: 1974-08-01
Abstract: 1428938 2,5 - Dideoxy - streptamines SCHERICO Ltd 1 Aug 1974 [6 Aug 1973] 33966/74 Heading C2C Novel compounds (I) and (III) and their acid addition salts in which one of R 1 and R 2 is hydrogen and the other is hydrogen or C 1-4 alkyl, are prepared by reacting cis-4,8-dioxatricyclo-[5,1,O,O<SP>3,5</SP>]-octane with a hydrazine NHR 1 -NHR 2 to form a compound III or a racemate thereof which may be resolved (when one of R 1 and R 2 is C 1-4 alkyl) and, if desired hydrogenolysing a compound (III) and isolating the compound (I) formed as such, as a racemic mixture (when one of R 1 and R 2 is C 1-4 alkyl) or in the form of an acid addition salt.
[GB1428938A]
Patent IE-812075-L (IE)
Title: Composition
IPC: A61K31/44
Filed: 1981-09-08
Abstract: 1. A solid pharmaceutical composition containing as the active ingredient nifedipine crystals with a specific surface area of 0,5 to 6 m**2 /g, in admixture with a solid diluent.
[EP0047899A1]
Patent IE-822700-L (IE)
Title: Radiographic element
IPC: G03C1/035
Filed: 1982-11-12
Abstract: Radiographic elements are disclosed comprised of first and second imaging portions separated by an interposed support capable of transmitting radiation to which the second imaging portion is responsive. At least the first imaging portion includes a silver halide emulsion in which high aspect ratio tabular silver halide grains are present. Spectral sensitizing dye is adsorbed to the surface of the tabular grains. Crossover can be improved in relation to the imaging characteristics.
[US4411986A]
Patent IE-812758-L (IE)
Title: Switching exchange
IPC: H04Q3/54
Filed: 1981-11-25
Abstract: An addressing circuit has a register search counter (20) connected to a first multiplexer (24) and to a second multiplexer (25), a memory (33) connected to the output of the first multiplexer for writing the type of processing of each register, a register counter (26) connected to the second multiplexer which is itself connected by its output to three address registers (28, 30, 32) in series. The output of the second register (30) is connected to the first multiplexer to write address the memory under the control of a write signal (CRW). The register search counter read addresses the memory and stops as soon as a register requiring rapid processing is detected; the second multiplexer receives a transfer signal (ST) to transmit the address applied to the output of the register search counter; the register counter (26) stops during the transfer signal.
[US4431992A]
Patent IE-813011-L (IE)
Title: Surgical sutures
IPC: A61L15/26
Filed: 1981-12-21
Abstract: A high compliance monofilament surgical suture having unique handling and knot tying characteristics, said suture comprising an oriented monofilament of poly[tetramethylene terephthalate-co-(2-alkenyl or alkyl) succinate].
[US4388926A]
Patent NO-801621-L (NO)
Title: Kjoelesystem for en gassturbin med en sylindrisk innsats med v-formede skaar
Inventor: GRONDAHL CLAYTON MERRILL
IPC: F01D5/08
Filed: 1980-05-30
Abstract: Et forbedret kjølesystem for en gassturbin om-tales. Et antall U-formede hakkåpninger (58) benyttes for å fordele en kjølemiddelvæske fra et kjølemiddelbasseng inn i et antall platå- og aerofoilkjølemiddelkanaler (30,. 32) utformet i turbinens skovler (18). De U-formede hakkåpninger (58) er utformet i en separat maskinert sylindrisk innsats (72) og tjener til å nedsette påvirkningen av kon-struksjonstoleransene og en ikke ensartet strømningsdi-stribusjon på kjølemiddelstrømmen inn i de enkelte platå-og aerofoilkjølemiddelkanaler (30, 32).
Patent NO-810361-L (NO)
Title: Didodecylammonium beta-oktamolybdat og sammensetning inneholdende dette.
Inventor: KROENKE WILLIAM JOSEPH
IPC: C07F11/00
Filed: 1981-02-03
Abstract: Didodecylammonium beta-oktamolybdat beskrives som et nytt aminmolybdat og som et røkretarderende additiv for vinylklorid- og vinylidenklorid-polymer-sammensetninger.
Patent NO-823408-L (NO)
Inventor: EKBLADH FRED VAAGE
IPC: A61B17/34
Filed: 1982-10-12
Abstract: A surgical trocar comprising a flattened oblong unit having at the front end an angled sharpened cutting edge, and at the rear end a device for removably attaching a tube for drainage or other purposes. The trocar's cutting edge produces fissure-shaped skin incisions which heal more easily than circular wounds, and the trocar's flattened shape reduces the risk of slippage and attendant damages to the patient and/or surgeon's hand from such slippage.
Patent NO-833565-L (NO)
Inventor: WAGNER ECKHART
IPC: B01D53/14
Filed: 1983-09-30
Abstract: CO2 and, where relevant, H2S are removed from natural gases which contain CO2 and may or may not contain H2S by a process in which the said natural gases are treated, in an absorption stage at from 40 DEG to 100 DEG  C., with an aqueous absorption liquid containing from 20 to 70% by weight of methyldiethanolamine, the treated natural gases are taken off at the top of the absorption stage, the aqueous absorption liquid laden with CO2 and, where relevant, H2S is taken off at the bottom of the absorption stage and then regenerated in one or more flash stages, and the regenerated absorption liquid is recycled to the absorption stage.
Patent NO-834561-L (NO)
Title: Fremgangsmaate og innretning for termoremanent duplisering av magnetbaand
Inventor: CHOUINARD MICHAEL PATRICK
IPC: G11B5/86
Filed: 1983-12-12
Abstract: En fremgangsmåte og en innretning for termoremanent duplisering av et magnetbånd som er spesielt tilpasset for laseroppvarming, ved hjelp av hvilken et kopibånd (14) oppvarmes og avkjles i en spalte mellom to valser (25, 26) mens det er i kontakt med. et originalbånd (11). i
Patent NO-844921-L (NO)
Inventor: BEUTIER DIDIER
IPC: C01G5/00
Filed: 1984-12-07
Abstract: The invention relates to a process for recovering silver in sulfuric solutions. Its characterizing feature is that the silver solution is contacted with a quantity of zinc sulfide which is at least equal to the stoichiometric quantity and the surface area of which is at least equal to K Ag2/3 x V, K being a constant, Ag being the silver concentration in the solution expressed in kilograms per cubic meter, and V the volume of the solution in cubic meters, the surface area being expressed in square meters and the value of K being greater than or equal to approximately 10. Application to the recovery of silver in zinc plant residues.
Patent NO-863167-L (NO)
Inventor: MOLEN THEODORUS JACOBUS VAN DE
IPC: C08J5/18
Filed: 1986-08-05
Abstract: Blown film on the basis of polyethylene with a density below 910 kg/m³ is prepared by extruding the molten polymer at temperatures of the melt at the die gap of at most 160◊C, the die gap width being at least 1mm, blowing the molten polymer to a balloon, cooling, flat­tening and rolling it up. Films that have been prepared this way have improved mechanical and optical properties.
Patent NO-880471-L (NO)
Title: Kompressoraggregat med en skruekompressor eller lignende.
Inventor: HRABAL HANS
IPC: F04D25/02
Filed: 1988-02-03
Abstract: Et kompressoraggregat består av en skruekompressor (2). og en drivmotor (1). Disse er drivforbundne med hverandre ved hjelp av en inn- og utkoplbar kopling (3). Motoren kan for regulering av skruekompressorens. (2) transportmengde stoppes periodisk. For å muliggjøre en start av kompressoraggregatet uten termisk overbelastning av drivmotoren (1) er den mellom drivmotoren (1) og skruekompressoren (2) Innlagte kopling utført som en i og for seg kjent sentrifugalkraftkopling (3) hvis drivende koplingsdel (17) er forbindbar med den drevne koplingsdel (18) ved hjelp av friksjonsskiver (23,28). For automatisk betjening av sentrifugalkraftkoplingen (3) er det anordnet et sjaltekammer (21) med en trykkskive (36) som under påvirkning av sentrifugalvekter (34) kan forstilles mot friksjonsskivene (23,28). Trykkskiven (36) kan være forsynt med returfjærer (40) og en av friksjonsskivene (23) i den drivende koplingsdel (17) kan ved hjelp av en eller flere ringfjærer (41) være presspåvirket mot sjalte-kammerets (21) trykkskive (36). I friksjonsskivene (23) er det anordnet lufteboringer (45) og lufteslisser (46).
Patent NO-902045-L (NO)
Inventor: SMITS GUIDO FREDDY
IPC: C08J9/14
Filed: 1990-05-09
Abstract: This invention relates to rigid closed-celled polyisocyanate-based foams exhibiting improved dimensional stability and a process for their preparation. In particular, it relates to resulting foams containing within their cells, a gas mixture comprising from 15 to 70 mole percent carbon dioxide and from 30 to 85 mole percent of a halocarbon mixture. The halocarbon mixture itself, comprises (a) from 40 to 95 mole percent based on moles of (a) and (b) present of a halocarbon compound having a boiling point of at least 283 DEG K, and (b) from 50 to 60 mole percent of a halocarbon compound having a boiling point equal to or less than 266 DEG K. Preferred halocarbons for component (a) and (b) are ethane halocarbons especially fluorodichloroethane or dichlorotrifluoroethane and chlorodifluoroethane, respectively.