baber/WOPTO huggingface dataset:
Patent IL-113665-A0 (IL)
Title: Amide derivatives their preparation pharmaceutical compositions containing them and their use
IPC: C07C45/46
Filed: 1995-05-09
Abstract: PCT No. PCT/GB95/01040 Sec. 371 Date Nov. 8, 1996 Sec. 102(e) Date Nov. 8, 1996 PCT Filed May 9, 1995 PCT Pub. No. WO95/30645 PCT Pub. Date Nov. 16, 1995A compound of formula (I), wherein R1 and R2 are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R1 and R2 are not fluoro; R3 and R4 are independently selected from hydrogen and C1-6 alkyl, and pharmaceutically acceptable salts, solvates or physiologically functional derivatives thereof, their use in medicine, particularly the phrophylaxis or treatment of conditions associated with inflammation, arthritis, or pain, pharmaceutical compositions comprising them, and processes for their preparation are disclosed.    <IMAGE>  (I)
Patent IL-122290-A0 (IL)
Title: Lipid-nucleic acid complex its preparation and use
IPC: A61K9/127
Filed: 1996-06-06
Abstract: Novel lipid-nucleic acid particulate complexes which are useful for in vitro or in vivo gene transfer are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. Upon removal of a solubilizing component (i.e. detergent or an organic solvent) the lipid-nucleic acid complexes form particles wherein the nucleic acid is serum-stable and is protected from degradation. The particles thus formed have access to extravascular sites and target cell populations and are suitable for the therapeutic delivery of nucleic acids.
Patent IL-127558-A0 (IL)
Title: Hepatocyte growth factor receptor agonists and uses thereof
IPC: A61K45/00
Filed: 1997-06-20
Abstract: Hepatocyte growth factor (HGF) receptor agonists are provided. The HGF receptor agonists include HGF receptor antibodies and fragments thereof. The HGF receptor agonists can be employed to substantially enhance HGF receptor activation. The HGF receptor agonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the HGF receptor agonists are also provided.
Patent IL-145186-A0 (IL)
Title: Formation and anion-exchange of crystalline echinocandin ammonium salts
IPC: C07K7/56
Filed: 2000-03-02
Abstract: A method is described for forming a crystalline Echinocandin nucleus salt from its mixed broth and/or partially purified process streams by the steps of nanofiltration to form a concentrate, addition of an aldehyde derivatizing agent which interacts with an aldehyde impurity, addition of an acid/metal salt to form a solubilized echinocandin nucleus salt having the desired anion, and subsequent cooling of the mixture to crystallize the salt.
Patent IL-148207-A0 (IL)
Title: Adaptive data rate control for narrowcast networks
IPC: H04B7/185
Filed: 2000-08-16
Abstract: A system to provide narrowcast communications uses adaptive data rate control to individual subscribers such that the effects of precipitation or other link conditions, which are not common to all subscribers, is mitigated. The invention takes advantage of the fact that the narrowcast data consist of packets which are individually addressed to specific subscribers, or groups of subscribers. The narrowcast data is communicated on a plurality of channels, each of potentially differing data rates. The subscribers are assigned a particular channel, based upon their link quality, to receive packets addressed to them. The lower data rate channel will be less affected by adverse link conditions and are hence assigned to subscribers most likely to incur adverse link conditions.
Patent IL-157222-A0 (IL)
Title: 2-heteroaryl-3,4-dihydro-2h-pyrrole derivatives and the use thereof as pesticides
IPC: C07D333/22
Filed: 2002-01-31
Abstract: Novel Delta<SUP>1</SUP>-pyrrolines of the Formula (I) in which R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and Het have the meanings given in the description, a plurality of processes for preparing these compounds and their use for controlling pests, and also novel intermediates and processes for their preparation.
Patent IL-157774-A0 (IL)
Title: An ophthalmic lens
IPC: A61F2/16
Filed: 2002-03-20
Abstract: An ophthalmic lens comprising a diffractive part and a method for designing such a lens.  According to the invention the ophthalmic lens further comprises a refractive part comprising at least one surface, which is configured to compensate a passing wavefront at least partly for at least one type of monochromatic aberration introduced by at least one of the optical parts of the eye. Said diffractive part is capable of compensating a passing wavefront at least partly for chromatic aberration introduced by at least one of the optical parts of the eye. Furthermore said refractive and diffractive parts together contribute to a required power of the lens.
Patent IL-171875-A0 (IL)
Title: Pioglitazone salts,such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same
IPC: A61P3/08
Filed: 2005-11-10
Abstract: Water-soluble salts of pioglitazone especially pioglitazone sulfate are useful in pharmaceutical applications.
Patent IL-183645-A0 (IL)
Title: Process for the preparation of drospirenone
Filed: 2007-06-04
Abstract: A process is described for the preparation of drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action; comprising the oxidation of 17±-(3-hydroxypropyl)-6²,7²,15²,16²-dimethylene-5²-androstane-3²,5,17²-triol.
Patent IL-188522-A0 (IL)
Title: Modulators of body weight, corresponding nucleic acids and proteins and diagnostic and therapeutic uses thereof
IPC: C07K14/47
Filed: 1995-08-17
Abstract: The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of weight, and to the diagnostic and therapeutic uses to which such modulators may be put. In its broadest aspect, the present invention relates to the elucidation and discovery of nucleotide sequences, and proteins putatively expressed by such nucleotides or degenerate variations thereof, that demonstrate the ability to participate in the control of mammalian body weight. The nucleotide sequences in object represent the genes corresponding to the murine and human OB gene that have been postulated to play a critical role in the regulation of body weight and adiposity. Preliminary data, presented herein, suggests that the polypeptide product of the gene in question functions as a hormone. The present invention further provides nucleic acid molecules for use as molecular probes, or as primers for polymerase chain reaction (PCR) amplification, i.e., synthetic or natural oligonucleotides. In further aspects, the present invention provides a cloning vector, which comprises the nucleic acids of the invention; and bacterial, insect, or a mammalian expression vector, which comprises the nucleic acid molecules of the invention, operatively associated with an expression control sequence. Accordingly, the invention further relates to a bacterial or a mammalian cell transfected or transformed with an appropriate expression vector, and correspondingly, to the use of the above-mentioned constructs in the preparation of the modulators of the invention. Also provided are antibodies to the OB polypeptide. Moreover, a method for modulating body weight of a mammal is provided. In specific examples, genes encoding two isoforms of both the murine and human OB polypeptides are provided.
Patent RO-125898-A0 (RO)
Title: Ared
Inventor: POPESCU NICOLAE
IPC: B62M1/36
Filed: 2010-08-11
Abstract: The invention relates to transportation means driven by human force, meant to be employed for carrying certain goods, for sports and leisure. The claimed transportation means consists of a horizontal frame comprising four components (36 and 37), two longitudinal components and two cross components, respectively, a pedal platform comprising three components (39 and 40) being mounted on said cross components, where the third component (40) makes the connection with a front part, on the two longitudinal components (36) of the horizontal frame there being mounted two trapezium-shaped eyes (34) within each of them there being mounted a bearing box (33) which, by means of two axles (29), makes the connection with some external pedal levers (28) which are mounted opposite to some internal pedal levers (27), on some pedal axles (18), by which some driving wheels are put into motion, at the end of the internal pedal levers (27) there being mounted two axles (44) passing through two bearing boxes (47) whereto two shoes (48) are welded, a pedal seat (50) being mounted thereon by means of four screws (49).
Patent RO-131563-A0 (RO)
Title: Tubular bioreactor with partial recirculation of liquid effluent
Inventor: MATEESCU CARMEN
IPC: C12M1/107
Filed: 2016-05-09
Abstract: The invention relates to a bioreactor for anaerobically treating wastewater with high organic load. According to the invention, the bioreactor consists of an underground fermenter (1) of cylindrical tubular shape, made of fiber glass with a D:L ratio of 1:3, a volume of 4...10 m, covered with an insulating layer (2), provided with a longitudinal separating wall (3), having at the upper part a drainage groove (4) which allows the liquid effluent to be partially recycled, a supply pipe (7) which connects the fermenter (1) to a supply tank (5) and, by means of a discharging pipe (8), to a discharge tank (9) which communicates by means of a separating wall with an expansion chamber (11), the tanks (5 and 9) and the chamber (11) being covered with a lid (12) provided with two apertures (13 and 14) for supplying the organic mass and for discharging the fermented sludge, respectively.
Patent RO-135857-A0 (RO)
Title: Method for purifying oocysts of pathogenic digestive coccidia with sodium amidotrizoate
Inventor: LAZĂR LIDIA-ELENA
IPC: G01N33/50
Filed: 2021-12-16
Abstract: The invention relates to a method of separating and purifying oocysts from pathogenic digestive coccidia. According to the invention, the method consists of the following steps: isolation of pathogenic digestive coccidia oocysts from fecal samples, purification in linear gradient at the interface 0.5% Ficoll-16% sodium amidotrizoate, ultrasound treatment at 8 ... 10 cycles/sec, minimum 75% of the purified oocysts being broken, the use of purified oocysts to obtain a total parasitic (mural and cytosolic) antigen with an optimal level of parasitic protein concentration of 2.3 mg%.
Patent AP-2000001994-A0 (AP)
Title: Process for the solid phase synthesis of of aldehyde, ketone, oxine, amine, hydroxamic acid and B-unsaturated carboxylic acid and aldehyde compounds.
Inventor: SALVINO JOSEPH M
IPC: C07C209/00
Filed: 1999-06-23
Abstract: This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and a,b-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.
Patent AP-2001002282-A0 (AP)
Title: Water dispensing apparatus with filter integrity testing system.
Inventor: TANNY GERALD
IPC: G01N15/08
Filed: 2000-04-03
Abstract: Water dispenser, which comprises, in addition to a water container, a filter element contained within a filter housing having an inlet and a dispensing outlet, a source of pressure and first valve and first conduit means for feeding water from the container to the filter housing inlet; means for feeding gas to the filter inlet to create gas pressure at the inlet, consiting of a reservoir, second valve and conduit means for controling the level of the water in the reservoir, and the control means comprise third conduit and valve means for permitting or preventing the admission of water into the reservoir, a pressure gauge for monitoring the pressure at the filter inlet; and control means forcontrolling the gas feeding means to cause or stop the feeding. The source of pressure may be a copressed gas cylinder provided with valve and conduit means for controlling the admission of compressed gas from the cylinder into the water container, and the means for feeding gas to the filter inlet comprise conduit and valve means for feeding gas to the inlet directly from the gas cylinder.
Patent IE-910548-A1 (IE)
Title: Acyl compounds
Inventor: BUHLMAYER PETER
IPC: C07C229/38
Filed: 1991-02-18
Abstract: Aromatic amide derivatives of formula (I) and their salts are new. (Where R1 = aliphatic hydrocarbon optionally substituted with halogen or OH, or a cycloaliphatic or araliphatic hydrocarbon. X1 = CO, SO2, or OCO with the carbon linked to the N. X2 = aliphatic hydrocarbon (optionally substituted with OH, carboxy, NH2, guanidino, cycloaliphatic or aromatic hydrocarbon) or cycloaliphatic hydrocarbon, with a carbon of the aliphatic optionally bridged by a divalent aliphatic hydrocarbon. R2 = carboxy or its ester or amide derivative, NH2, substituted amino, formyl, acetal derivative of formyl, 1H-tetrazol-5-yl, pyridyl, OH, ether, SR, SOR, SO2R, alkanoyl, sulphamoyl, N-substituted sulphamoyl, PO2H2 or PO3H2. R = H or aliphatic hydrocarbon. X3 = hydrocarbon. R3 = carboxy, 5-tetrazolyl, SO3H, PO2H2, PO3H2 or haloalkylsulphamoyl. Rings A and B are each optionally substd. 121 compounds are specifically claimed, including (S)-N-(1-carboxy -2-methyl)-prop-1-yl) -N-pentanoyl-N- (2'-(1H-tetrazol-5-yl) biphenyl-4-ylmethyl) amine.
Patent MA-27709-A1 (MA)
Title: ALCALOiDES TERPENIQUES ANTIPARASITAIRES
Inventor: CHUBB NATHAN ANTHONY LOGAN
IPC: C07D498/04
Filed: 2005-08-12
Abstract: DEPOSANT Société dite : PFIZER INC. REVENDICATION DE PRIORITES GB 14 Février 2003 0303439.4 Alcaloïdes terpéniques antiparasitaires La présente invention concerne des alcaloïdes terpéniques nouveaux et leur utilisation comme agents antiparasitaires. La présente invention concerne également un agent antiparasitaire qui comprend un alcaloïde terpénique de la présente invention comme ingrédient efficace dans une formulation antiparasitaire. Plus particulièrement, la présente invention concerne des dérivés de l'alcaloïde terpénique (2S, 3aR, 9bR)-6-chloro-9b-hydroxy-5-méthyl-1,2,3,3a,5,9b-hexahydropyrrolo[2, 3-c] [2, 1]benzoxazine-2-carboxylate de (1S,2R,4aS,5R,8R,8aR)-2-(acétyloxy)-8a-hydroxy-3,8-diméthyl-5-(1-méthyléthényl)-1,2,4a,5,6,7,8,8a-octahydronaphtalène-1-yle. Des compositions pharmaceutiques les comprenant sont également décrites.
Patent MA-37737-A1 (MA)
Title: Dispositif bucco-dentaire embarque de dosettes de fluide
Inventor: ZAOUI FATIMA
IPC: A61C17/02
Filed: 2014-12-31
Abstract: Nous avons conçu et fabriqué un dispositif d’irrigation bucco-dentaire permettant le nettoyage et l’irrigation simultané des dents et des muqueuses d'au moins une arcade, caractérisé par la présence une gouttière, mono ou bi-maxillaire, recouvrant ou non les dents respectivement d’une arcade ou des deux arcades avec comme spécificité des incrustations ou logettes aménagées pour des dosettes remplies de fluide d’irrigations bucco-dentaire. Les dosettes peuvent être rechargées selon la demande. Fabriquée en un matériau souple d’usage médical. Indiquée en cas de sécheresse buccale. Une fois la gouttière mise en place sur les dents pour irrigation bucco-dentaire, en fonction de la demande en terme de quantité de liquide, le patient peut appuyer (action mécanique) sur les dosettes intégrées dans la gouttières pour extraire le fluide de la dosette et assurer sa circulation sur les dents et les muqueuses.
Patent MA-38636-A1 (MA)
Title: Composés de 3,4-dihydroisoquinoléin-2(1h)-yle
Inventor: BEADLE CHRISTOPHER DAVID
IPC: C07D217/16
Filed: 2014-05-27
Abstract: L'invention concerne certains composés de 3,4-dihydroisoquinoléin-2(1h)-yle, notamment des composés de formule (i), et des compositions pharmaceutiques correspondantes. L'invention concerne en outre des procédés d'utilisation d'un composé de formule (i) pour traiter la déficience cognitive associée à la maladie de parkinson ou à la schizophrénie.
Patent MA-39148-A1 (MA)
Title: Composition siliceuse et procede d'obtention
Inventor: DI LORETO OSVALDO
IPC: F27D1/16
Filed: 2016-06-23
Abstract: Composition pulvérulente à base de silice pour soudure céramique, en particulier par projection, comprenant - de 10 à 90 % d'une phase de particules siliceuses comprenant au moins 80 % en poids de cristobalite et au plus 15% en poids de tridymite, par rapport au poids total de la composition, - de 90 à 10 % en poids d'additifs conventionnels formant une phase liante, par rapport au poids total de la dite composition, lesdites particules siliceuses présentant un d
Patent MA-53768-A1 (MA)
Title: Estimation de forme spectrale à partir de coefficients mdct
Inventor: SEHLSTEDT MARTIN
IPC: G10L19/02
Filed: 2020-02-20
Abstract: L'invention concerne un procédé, un décodeur et un code de programme pour commander un procédé de dissimulation pour une trame audio perdue. Une première trame audio et une seconde trame audio d'un signal audio reçu sont décodées pour obtenir des coefficients de transformée en cosinus discrète modifiée (mdct). Des valeurs d'une première forme spectrale basées sur les coefficients mdct décodés à partir de la première trame audio décodée et des valeurs d'une seconde forme spectrale basées sur des coefficients mdct décodés à partir de la seconde trame audio décodée sont déterminées, les formes spectrales comprenant chacune un certain nombre de sous-bandes. Les valeurs des formes spectrales et des énergies de trame de la première trame audio et de la seconde trame audio sont transformées en représentations d'analyses spectrales basées sur des fft. Une condition transitoire est détectée sur la base des représentations des fft. En réponse à la détection de la condition transitoire, le procédé de dissimulation est modifié par réglage sélectif d'une amplitude de spectre d'un spectre de trame de substitution.
Patent MA-59341-A1 (MA)
Title: Analogues de rifamycine et conjugués anticorps-médicament de ceux-ci
Inventor: NITTOLI THOMAS
IPC: C07D498/18
Filed: 2021-07-28
Abstract: L'invention concerne des composés analogues de rifamycine, des intermédiaires et des précurseurs de ceux-ci, et des compositions pharmaceutiques capables d'inhiber la croissance bactérienne (par exemple, la croissance de s. Aureus) et de traiter des infections bactériennes (par exemple, des infections par s. Aureus). L'invention concerne en outre des conjugués anticorps-médicament de composés analogues de rifamycine et d'anticorps, par exemple, des anticorps spécifiques contre des cibles associées à une maladie infectieuse comme le récepteur de glycoprotéine membranaire (msr1), des acides téichoïques de paroi (wta) ou une protéine a, et des procédés d'utilisation de ceux-ci pour inhiber la croissance bactérienne et traiter des infections bactériennes.
Patent UY-25301-A1 (UY)
Title: Procedimiento para producir una alfombra de mechones y alfombra comprendiendo tela con y sin mechones.-
Inventor: RAFAEL LETTIERE NETO
IPC: D05C17/02
Filed: 1998-12-14
Abstract: La presente invención se refiere, en general, a un procedimiento de fabricación de alfombras con mechones, utilizados, por ejemplo, en la decoración de hogares y aún a alfombras del tipo producido por el procedimiento. Dicho procedimiento incluye las siguientes etapas: - obtener un pedazo de alfombra antes de la aplicación de goma sobre el lado inferior de su base; - remover los mechones de una región de la superficie de la tela de base del pedazo de alfombra; y - proveer dicha región de la superficie de la tela de base con otros mechones de naturaleza distinta, utilizándose una máquina de comando manual. Finalizando la fabricación de la alfombra, se lleva a cabo la aplicación de goma, que se caracteriza por colocarse una base sobre la superficie inferior de la tela de base para fijar definitivamente los mechones en la tela de base. Se obtiene una alfombra de excelente calidad y acabamiento, que es comparable con cualquier alfombra confeccionada de forma semi artesanal, pero con la ventaja de tener un costo de fabricación mucho más bajo, por el hecho de que se hace uso de un alfombrado ya fabricado en gran escala.
Patent UY-25367-A1 (UY)
Title: Conjunto de bomba hidraulica con calentador electrico para bañeras de hidromasaje.
Inventor: GIORIA CLESO
IPC: H05B1/02
Filed: 1999-01-22
Abstract: Conjunto de bomba hidráulica con un calentador eléctrico integralmente ideado para bañeras de hidromasaje y que comprende: una bomba hidráulica; un motor eléctrico para accionar la bomba hidráulica para hacer circular el agua; un interruptor para prender el motor y bomba; un calentador eléctrico acoplado al motor y bomba, con resistencia eléctrica en una camara de calentamiento; un segundo interruptor para dar energía a la resistencia responsable de accionar el primer interruptor para dar energía a la resistencia eléctrica cuando el motor y la bomba está prendido . Un termostato de seguridad para el apagado de la resistencia electrica cuando no hay agua en el calentador, los interruptores electricos accionados a distancia por dispositivos neumaticos para evitar riesgo de choque electrico por contacto con las partes activas del dispositivo.
Patent UY-26300-A1 (UY)
Title: Compuestos y métodos biológicos para mejorar el crecimiento y la salud de las plantas y para producir plantas capaces de suprimir enfermedades.
Inventor: KENNEY JOSEPH KLOEPPER DR RODR
Filed: 2000-08-17
Abstract: Acelera el crecimiento de todo tipo de plantas y mejora su salud. Aumenta la tasa de crecimiento y sirve para producir semillas con un recubrimiento que suministra resistencia contra las enfermedades, acortando el tiempo necesario para producir transplantes en plantas jóvenes de invernadero, antes de que sean transplantadas a campos de agricultura. Desarrolla mudas de transplante que suprimen enfermedades, y permanecen protegidas por un tiempo contra múltiples enfermedades a través de mecanismos combinados de estimulación de las defensas de la planta y por una mayor actividad de microorganismos antagónicos indígenas que se encuentran en las raíces de las plantas.
Patent UY-29549-A1 (UY)
Title: Nuevos derivados del fluoreno, composiciones que los contienen y su utilización
Inventor: PATRICK MAILLIET
IPC: A61P25/00
Filed: 2006-05-19
Abstract: La invención se refiere a nuevos derivados del fluoreno de fórmula (I), donde sustituyentes y radicales son tales como se especifican en la Memoria Descriptiva y en las Reivindicaciones, estando estos productos en todas las formas de tautómeros e isómeros y las sales, como medicamentos.
Patent AT-524715-A1 (AT)
Title: Verfahren und Vorrichtung zur Nachverfolgung von Tieren
IPC: A01K29/00
Filed: 2021-02-12
Abstract: Bei einem Verfahren zur Nachverfolgung von Tieren, insbesondere Rindern, sind die folgenden Schritte vorgesehen: kontinuierliche digitale Bilderfassung einer Mehrzahl von Tieren, um digitale Bilddaten zu erhalten, Identifizieren einzelner Tiere mittels eines Algorithmus zur Merkmalsextraktion aus den Bilddaten, Nachverfolgung der Fortbewegung der identifizierten Tiere, um erste Bewegungsdaten zu erhalten, Analysieren der ersten Bewegungsdaten, um ein Fortbewegungsprofil jedes Tieres zu erstellen, Nachverfolgung der Bewegung einzelner Körperteile der Tiere unter Verwendung der bei der Merkmalsextraktion erkannten Körpermerkmale, um zweite Bewegungsdaten zu erhalten, Analysieren der zweiten Bewegungsdaten, um die Körperlage und/oder die Tätigkeit der Tiere zu ermitteln, um ein Verhaltensprofil jedes Tieres zu erstellen, Ermitteln des Tierwohls jedes Tieres aus dem Fortbewegungsprofil und dem Verhaltensprofil
Patent DZ-350-A1 (DZ)
IPC: C07K14/56
Filed: 1981-11-09
Granted: 2004-09-13
Abstract: Microbially produced hybrid human leukocyte interferons, useful in the treatment of viral and neoplastic diseases, and means used in their production, i.e. recombinant DNA molecules coding for the amino acid sequences of these interferons, vectors capable of expressing these interferons in microbial host organisms and host organisms transformed with these vectors.