baber/WOPTO huggingface dataset:
Patent NZ-733168-A (NZ)
Title: Novel immunotherapy against several tumors, such as lung cancer, including nsclc
Inventor: WEINSCHENK TONI
IPC: C12N5/0783
Filed: 2014-08-04
Abstract: The present invention relates to peptides, nucleic acids, binding agents, methods and cells for use in immunotherapy. In particular, the present invention relates to a peptide which consists of the sequence KIQEMQHFL (SEQ ID No.2), or comprises said sequence and is up to 14 amino acids in length, as well as its use in immunotherapy for cancer. The present invention furthermore relates to tumour-associated cytotoxic T lymphocyte (CTL) peptide epitopes, alone or in combination with other tumour-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumour immune responses. The present invention relates to a peptide sequence derived from HLA class 1 molecules of human tumour cells that can be used for eliciting anti-tumour immune responses.
Patent NZ-737018-A (NZ)
Title: Pd-l1 antagonist combination treatments
Inventor: ANDREWS GLEN IAN
IPC: A61K31/4439
Filed: 2016-06-15
Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death Ligand 1 receptor (PD-L1) (Avelumab) and a VEFGR inhibitor that is is N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide (axitinib) for the treatment of cancer.
Patent NZ-743635-A (NZ)
Title: Biomarker for use in treating anemia
Inventor: CHOPRA RAJESH
IPC: G01N33/72
Filed: 2013-10-23
Abstract: Provided herein are methods of treating diseases associated with anemia or ineffective erythropoiesis by using the level and/or activity of a ligand of an activin receptor, in particular, Growth differentiation factor 11 (GDF11), as an indicator of responsiveness of a patient to the treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type II receptor inhibitor. In particular, the present invention relates to the use of an activin receptor type II inhibitor for treating anemia, beta thalassemia, increasing red blood cell levels, increasing orthochromatic erythroblasts (Ery-C), inherited bone marrow failures or myelodsplastic syndromes in patients having elevated GDF11 levels. GDF11 levels are used as a biomarker of treatment efficacy.
Patent NZ-752434-A (NZ)
Title: Pharmaceutical composition
Inventor: CORR STUART
IPC: A61P11/00
Filed: 2017-09-18
Abstract: A pharmaceutical composition is described. The composition comprises:(i) a drug component comprising at least one beclomethasone compound selected from beclomethasone and the pharmaceutically acceptable derivatives thereof and at least one long acting beta-2-agonist; and (ii) a propellant component comprising 1,1- difluoroethane (HFA-152a).
Patent NZ-752711-A (NZ)
Title: Clutch engagement assembly of door lock and driving device thereof
Inventor: TAE HOON KWON
IPC: E05B15/00
Filed: 2019-04-17
Abstract: A door lock with a clutch engagement assembly includes a first shaft 41 having at an end thereof an insertion end portion 41a in which a channel 41h is formed; a second drive shaft 42 having a hollow engagement end portion 42a into which the insertion end portion of the first shaft 41 is inserted; a driving member which provides a driving force 60; and a pin member P1 that is installed in a state of being elastically supported in the engagement end portion of the second shaft and is movable by the driving member 60 so as to extending through (be inserted in) at least a part of the first shaft and at least a part of the second shaft, thereby causing a clutch engagement or a disengagement between a first shaft 41 and a second shaft 42. The clutch engagement assembly has a shape corresponding to the installation hole as a whole in a state where the motor unit is coupled to the mounting module. The clutch engagement assembly may provide a relatively small size structure of the door lock device and a firm engagement force.
Patent NZ-760206-A (NZ)
Title: Automated cell processing methods, modules, instruments, and systems
Inventor: MASQUELIER DON
IPC: G01N35/04
Filed: 2018-06-30
Abstract: In an illustrative embodiment, provided are automated multi-module cell editing instruments, modules, and systems are provided to automate editing, including nuclease-directed cell editing inside one or more cells in a cell population. Other specific embodiments of the automated multi-module cell editing instruments of the disclosure are designed for recursive genome editing, e.g., sequentially introducing multiple edits into genomes inside one or more cells of a cell population through two or more editing operations within the instruments.
Patent NZ-761139-A (NZ)
Title: Proportional Flow Control Valve Poppet With Flow Control Needle
Inventor: WILLIAMS KEVIN C
IPC: F16K27/02
Filed: 2020-01-24
Abstract: A flow control valve including a valve body, stepper motor, and valve member. The valve member includes a poppet that can slide longitudinally within a bore of the valve body when the stepper motor receives electricity. A diaphragm, extending inwardly from the valve body to the valve member, deflects in response to movement of the valve member. A flow control needle, mounted to the poppet of the valve member, is at least partially received in an outlet port of the valve body. The flow control needle 149 cooperates with an inner surface of the outlet port to define an outlet flow orifice that varies in size when the valve member moves between open and closed positions. In the closed position, a seat engagement surface of the valve member contacts a valve seat of the valve body to create a fluid-tight seal. The needle’s position is longitudinally adjustable to accommodate variances. The seat engagement surface is positioned at the distal poppet end 131 and is radially outward of said flow control needle 149. The valve is simpler, more accurate and requires less force to operate.
Patent NZ-773144-A (NZ)
Title: Stunner
Inventor: JONES ARTHUR
IPC: A22B3/00
Filed: 2017-06-30
Abstract: The present invention relates to a stunning rod 40’ adapted for use in an animal stunner 10. The rod 40’ is mountable with a piston 48 movable within an inner chamber 180 in the stunner 10. The inner chamber 180 has a catch 20 for alternately holding and releasing the stunning rod 40’. The rod 40’ comprises an elongated body 44’ having a longitudinal axis 42’, the elongated body 44’ having a forward end 310 and an opposite rearward end 312, the forward end 310 adapted to receive a nose for striking an animal’s head, and the opposite rearward end 312 adapted to receive an outwardly extending lip 46’ for engagement with the catch 20. The rod 44’ further comprises a mounting portion between the forward and rearward ends having an outwardly extending flange 48’ adapted to receive the piston 48. The elongated body 44’ of the stunning rod 40’ between the mounting portion and forward end has along at least a portion of the length a first pair of opposite sides having a first radius and a first width, and a second pair of opposite sides having a second radius and a second width, the radius of the second pair of opposite sides being different from the radius of the first pair of opposite sides, and the first width between the first pair of opposite sides being smaller than the second width between the second pair of opposite sides thus preventing its rotation in the inner chamber. The stunning rod 40’ being capable of being driven forward along a longitudinal axis within the stunner inner chamber 180 to stun an animal, and rearward along the longitudinal axis to retract and hold the stunning rod 40’ by the catch 20. The invention provides an animal stunner having improved operator comfort and reduction of possible injury, and in which the stunning rod slides easily and reliably without rotation.
Patent NZ-773765-A (NZ)
Title: Respiratory pressure therapy device
Inventor: SHADIE TIMOTHY NICHOLAS
IPC: A61M16/00
Filed: 2016-03-14
Abstract: Apparatus for generating a supply of air at positive pressure for the amelioration or treatment of a respiratory disorder, comprising: at least one chamber; a blower structured and configured to produce a flow of air at positive pressure; an inlet tube array including a plurality of inlet tubes structured and configured to allow ambient air to enter the at least one chamber; and a flow tube array including a plurality of flow tubes structured and configured to allow air to exit the at least one chamber, wherein the inlet tube array is axially spaced apart from the flow tube array, wherein the inlet tubes of the inlet tube array include axes that are arranged substantially parallel to axes of the flow tubes of the flow tube array, and wherein at least one of the inlet tubes includes an axis that is not coaxial with an axis of at least one of the flow tubes.
Patent PT-103854-A (PT)
Title: Sonda de ensaios não destrutivos por correntes de eddy
Inventor: SANTOS TELMO JORGE GOMES DOS
IPC: G01N27/90
Filed: 2007-10-19
Abstract: A PRESENTE INVENÇÃO CONSISTE NUMA NOVA SONDA DE CORRENTES DE EDDY, PARA APLICAÇÃO EM ENSAIOS NÃO DESTRUTIVOS, QUE TEM COMO OBJECTIVO AUMENTAR A CAPACIDADE DE DETECÇÃO DOS DEFEITOS COM DIMENSÃO OU MORFOLOGIA DE DIFÍCIL DETECÇÃO, POR VIA DA ELIMINAÇÃO DO EFEITO DE LIFT-OFF E DA PROXIMIDADE DA SONDA COM A SUPERFÍCIE DO MATERIAL A INSPECCIONAR. A SONDA CARACTERIZA-SE POR UMA CONCEPÇÃO INOVADORA, COM UMA BOBINA DE EXCITAÇÃO TOROIDAL, E UMA BOBINA SENSÍVEL ESPIRAL PLANA PERPENDICULAR À PRIMEIRA E PARALELA À SUPERFÍCIE DE INSPECÇÃO, O QUE ELIMINA O RUÍDO DO SINAL CAUSADO PELA VARIAÇÃO DA SUA POSIÇÃO RELATIVAMENTE AO MATERIAL A INSPECCIONAR, E PERMITE DETECTAR DEFEITOS QUE SERIAM MASCARADOS PELO RUÍDO DO LIFT-OFF. OUTRA VANTAGEM DA SONDA É A POSSIBILIDADE DE INSPECCIONAR OS BORDOS DO MATERIAL, E TAMBÉM OPERAR SEGUNDO UM MÉTODO DE INSPECÇÃO BASEADO NA ANÁLISE DO SINAL DURANTE UM MOVIMENTO DE ROTAÇÃO DE 360º DA SONDA SOBRE SI PRÓPRIA, PERMITINDO A DETECÇÃO DE DEFEITOS COM QUALQUER TIPO DE ORIENTAÇÃO.
Patent PT-105194-A (PT)
Title: Bomba de água estática
Inventor: RIACHO CARLOS OLIVEIRA
IPC: F03B13/14
Filed: 2010-07-09
Abstract: O INVENTO APRESENTADO REFERE-SE A UM SISTEMA DE BOMBA DE ÁGUA ESTÁTICA FIXADA AO FUNDO DO MAR, COM CAPACIDADE PARA BOMBEAR ÁGUA PARA TERRA EM GRANDE ESCALA COM ENERGIA RECUPERADA DAS ONDAS. O SISTEMA É CONSTITUÍDO POR DOIS ÓRGÃOS ESTÁTICOS, UM VASO(1) SUPORTE DUMA BATERIA DE FUNIS(2) E UM RESERVATÓRIO(4) QUE ALOJA NO SEU INTERIOR UM ACUMULADOR DE ENERGIA HIDROPNEUMÁTICA(5). A MAIOR ALTURA DA ÁGUA QUANDO AS ONDAS PASSAM EM CRISTA, ACRESCENTA FORÇA DE DIVERSAS TONELADAS NA BOCA DOS FUNÍS QUE, POR EFEITO DE PRENSA, INJECTAM ÁGUA PRESSURIZADA NO RESERVATÓRIO(4), ATRAVÉS DAS CONDUTAS(6) E DAS VÁLVULAS UNIDIRECCIONAIS(7), PARA ESPAÇO CEDIDO PELO EFEITO ELÁSTICO DO ACUMULADOR DE ENERGIA HIDROPNEUMÁTICA(5) QUE, ASSIM, ACUMULA ENERGIA PARA MANTER O BOMBEAMENTO QUANDO COM AS ONDAS EM CAVA. A ÁGUA PRESSURIZADA ESGOTA DO RESERVATÓRIO(4) PELA CONDUTA(S) PARA TERRA, ONDE PODE SER UTILIZADA: EM TURBINAS DE CENTRAIS ELÉCTRICAS, VIVEIROS PISCÍCOLAS, ARREFECIMENTO DOS CONDENSADORES EM CENTRAIS TÉRMICAS ETC.
Patent RO-82945-A (RO)
Inventor: FOUCHER GERARD
IPC: F16B2/04
Filed: 1982-01-23
Abstract: PCT No. PCT/FR81/00065 Sec. 371 Date Nov. 30, 1981 Sec. 102(e) Date Nov. 30, 1981 PCT Filed May 19, 1981 PCT Pub. No. WO81/03529 PCT Pub. Date Dec. 10, 1981.A connector for connecting two rotors (2, 4) together, said connector having a plate (1, 3) on the end of each rotor. It has clamping bolts (5) and a plurality of fixing components (6) for the plates (1, 3). Each fixing component (6) has a sleeve (17) cut in two. The sleeve is cylindrical on the outside and conical on the inside and is disposed in precision-reamed bores (12, 14) of the same dimensions in the two plates, the bores of one plate facing and being situated exactly adjacent to those of the other when the rotors (2, 4) are aligned. A shank (20) which has a conical portion (21) pushes back the parts of the sleeve (17) against the walls of the bores (12, 14) thus connecting the plates together without play. In the case of normal operation, the connector has high resistance to shearing due to the fact that there are no stresses in the components (6). In the case of a torque greater than the normal torque, the parts of the sleeve 17 are deformed but can be very easily extracted. The connector is used in turbo-alternators.
Patent RU-94002484-A (RU)
IPC: F41B6/00
Filed: 1994-01-24
Abstract: FIELD: space weapons and ecology. SUBSTANCE: missile is made in form of metal superflexible corrugation placed in barrel impermeable to air with descending, straight and ascending sections on Alpine plateau, where ascending section is located in ascending manner on the steep slope of mountain. Vacuum in barrel is created by compressors. High rare- faction in barrel mouth is maintained by jet gate. Vacuum of the side of descending section is ensured by hermetic magazine. Missile is inserted into magazine and accelerated by successively engaged electromagnets located on superstrong super-heat-resistant cast concrete barrel secured with screw-in anchors. Length of straightline, horizontal and ascending sections are congruent with all parameters, both, velocity ones, causing centrifugal and centripetal forces on curved sections, and strength ones. EFFECT: attaining space velocities directly on the launching ground in the Earth atmosphere by simple and efficient method.
Patent RU-94007067-A (RU)
Inventor: CHUMAEVSKIJ O V
IPC: C01B25/37
Filed: 1994-03-01
Abstract: FIELD: production of concentrates of phosphatation being used in automobile, machine building industries and others. SUBSTANCE: technical zinc oxide is used as origin zinc-containing raw materials. Initially aqueous suspension of zinc oxide is prepared, ratio of ZnO : HO in it being 1:1-3. Thus prepared suspension is fed into mixture of phosphoric and nitric acid, the process is carried out at rate 20-110 kg of ZnO/h m. Then thus obtained product is allowed to stand within 1-3 h by mixing, then separation of desired product against impurities takes place. EFFECT: prevents losses of nitrates, improved efficiency and safety of the method, improved quality of desired product.
Patent RU-94025975-A (RU)
Inventor: SERGEEV S A
IPC: B27K3/50
Filed: 1994-07-12
Abstract: FIELD: protective means for wood treatment; applicable in wood-working industry and construction. SUBSTANCE: the offered compound presents a fraction of wastes of phenol-acetone production including, mas.%: n-cumyl-phenol 32-45; dimers of alpha-methyl styrene 20-25; acetophenone 7-25; phenol 6-20; dimethylphenylcarbinol l-7. Compound is ecologically safe with observation of production rules and safety regulations. EFFECT: higher efficiency.
Patent RU-94028218-A (RU)
Inventor: BALAKIREV N A
IPC: A23K1/16
Filed: 1994-07-26
Abstract: FIELD: fur farming, and may be used for growing young stock of fur-bearing animals. SUBSTANCE: premix includes, mass%: vitamin A, 1.6-2.1; vitamin B, 0.9-1.3; vitamin B, 0.7-0.9; vitamin B, 2.1-3.2; vitamin B, 0.2-0.4; vitamin D, 0.4-0.8; vitamin E (25%), 21.5-31.3; vitamin C, 20.0-38.5; additionally premix comprises citric acid in the amount of 6.2-8.1 mass%, and agidol, 26-4-33.4 mass%. EFFECT: higher efficiency.
Patent RU-94033484-A (RU)
Inventor: GERKHARD SHTUKI
IPC: C07D487/04
Filed: 1994-09-16
Abstract: FIELD: medicine. SUBSTANCE: claimed invention describes novel process for preparing imidazopyridines of general formula:wherein R-Rare as defined in the specification. At final stage of the process, amidine of formula:is cyclized with 1,3-dicarbonyl compound of general formula:. Imidazopyridines are valuable intermediate products for preparation of angiotensine-II- antagonists. EFFECT: more efficient preparation process.
Patent RU-94034110-A (RU)
Inventor: KHORST FOGEL ZANG
IPC: F16L47/00
Filed: 1994-09-23
Abstract: FIELD: polyethylene pipes production. SUBSTANCE: pipeline link made by extrusion of polyethylene plastic has formed on it joining funnel. Formed by extrusion link of pipeline has wall thickness exceeding 5 mm. Formed on pipeline link joining funnel has approximately similar thickness of wall. Cross-section of wall has highly crystalline inner area and low crystalline outer area. Highly crystalline inner area forms going along circumference crystalline arch. It is determined for practically free from deformations resting of low crystalline outer area during arising shrinking strains. Method of the pipeline link production is described. EFFECT: improved process.
Patent RU-94035671-A (RU)
Inventor: UIL JAM A BERGSHTRESSER
IPC: A61M5/31
Filed: 1994-09-28
Abstract: FIELD: mechanical engineering. SUBSTANCE: device 10 to be connected with external thread has outer surface 12, chamber 14 open from outer surface 12 on which inner surface 16 of fins 18 depend. Fins 18 run longitudinally from outer surface 12. Device 10 may be connected with external thread by means of screwing chamber 14 on external thread. Device is made in form of plunger rod 10 which is used for connecting the rod with plunger pin provided with external thread of respective device, type sleeve-needle, for forming syringe unit. EFFECT: ease of manufacture by means of cast moulding excluding unscrewing stage. 2 dwg
Patent RU-94037796-A (RU)
IPC: H05B39/04
Filed: 1994-10-07
Abstract: FIELD: lighting engineering, in particular, illuminance regulators, applicable for regulation of illuminance produced by incandescent lamps used in various luminaires. SUBSTANCE: illuminance regulator has a rectangular casing, which accommodates the electronic control unit, using a variable resistor with a knob located on the casing, rotation of the knob causes variation of incandescent lamp illuminance. The control knob is made of transparent material, and located under the knob on the resistor shaft is an additional printed-circuit board with neon lamps serving as a night-light: at the maximum illumination by the incandescent lamps the neon lamps automatically go out, and at the minimum illumination by the incandescent lamps the neon lamp brightly glow. EFFECT: reduced power consumption, enhanced convenience in use: it is not necessary to switch on the regulator at night or leave the incandescent lamps glowing. 1 dwg
Patent RU-94042523-A (RU)
Inventor: SERGEEV A M
IPC: H04B1/30
Filed: 1994-11-23
Abstract: FIELD: radio engineering. SUBSTANCE: synchronous heterodyne receiver incorporates phase-locked-loop frequency control for synchronous reception of signals with amplitude, frequency, and phase modulation and also singleband signals with carrier residue. Signal is modulated in receiver by voltage of auxiliary low-frequency oscillator which makes it possible to replace DC voltage amplifiers by ac ones. In addition, receiver uses automatic gain control, and PLL system is provided with amplitude limiter. Receiver sensitivity can be brought to 5 mcV and lower still without using high-frequency amplifier. Block-diagram of receiver is given in description of invention. EFFECT: improved tuning stability, noise immunity, sensitivity. 1 dwg
Patent RU-94042565-A (RU)
Inventor: STAROKOZHKO L E
IPC: A61K31/704
Filed: 1994-11-29
Abstract: FIELD: medicine, immunology. SUBSTANCE: proposed composition shows immunostimulating action. Composition has glyciram at the dose 5 mg/kg body mass, distilled water and carbon dioxide as dispersion medium taken at volume ratio = (1:10)-(1:15). EFFECT: enhanced effectiveness of agent.
Patent RU-94045215-A (RU)
Inventor: MOSHKONOV V V
IPC: F03D9/00
Filed: 1994-12-27
Abstract: FIELD: wind power engineering. SUBSTANCE: wind drive is made up as a wind vane mounted on a rotatable head 1. The vane reciprocates in vertical plane of beam 3 and is provided with wings 14 on fin 12 on horizontal axle 13. EFFECT: simplified design.
Patent RU-95100941-A (RU)
Inventor: FAJUSTOV JU P
IPC: F16H33/02
Filed: 1995-01-24
Abstract: FIELD: drives of machines, flash lights, starters of internal combustion engines, toys, etc. SUBSTANCE: multi-stage accumulator has several spiral flat springs connected in succession in such way that outer end of each spring is connected to limiting ring of one holder and inner end is connected to hub of next holder. EFFECT: increased specific energy capacity of accumulator; simplified construction and reduced usage of metal. 2 cl, 1 dwg
Patent RU-95104085-A (RU)
Inventor: SHEVTSOV V I
IPC: A61B17/56
Filed: 1995-03-21
Abstract: FIELD: orthopedics and oncology. SUBSTANCE: tumor-like bone disease is treated by aid of compression-distraction apparatus using sound mother bone transplant taken from the region of affection locality. Transplant is formed from cortical bone wall on the extension corresponding to length of affected place. Pathologically changed tissues are resected, whereupon transplant is turned over and immersed with its outer surface into cavity to reach full contact with its inner wall. The place is finally fixed with apparatus. EFFECT: improved treatment procedure.
Patent RU-95104391-A (RU)
Inventor: BASARYGIN JU M
IPC: E21B23/00
Filed: 1995-03-24
Abstract: FIELD: borehole drilling. SUBSTANCE: magnetic sensor is used in the device for indicating on seating inclinometer onto the specified point, as well as multiple orientation on marks on device parts in the plane of deflector followed by stopping. EFFECT: decreased error in orientation. 1 dwg
Patent RU-95105212-A (RU)
Inventor: AKSENOV V V
IPC: H03K17/968
Filed: 1995-04-06
Abstract: FIELD: engineering, in particular, devices which controls vehicles. SUBSTANCE: device has light source, light receiver, and housing, which has jacket and guiding lathe which has N triangular teeth over which carriage is traveled. Carriage has U-shaped cramp which has two support, one spring- loading and one fixing rollers. In addition device has shutter and handle which is rigidly attached to carriage and is designed as parallelepiped with two blind holes, which axes are perpendicular. Pushing button is located in horizontal hole while fixer of neutral position is located in vertical hole. Light source and light receiver are mounted with space in opposite position. Said space is closed with shutter when carriage is involved in reciprocal movement when handle is pressed. Fixing roller provides possibility to fix moving carriage with shutter in precisely defined position with respect to optical pairs. Forces for movement of control handle which switches positions are moderate for operator; however for pressing roller to recesses of profiled lathes are heavy. EFFECT: increased reliability in usage due to fixation of handle in required position and prevention of its accidental movement caused by impact or vibration. 2 dwg
Patent RU-95106095-A (RU)
Title: Method for making radioactive materials ready to long-time safe storage
Inventor: KARELIN A I
IPC: G21F9/34
Filed: 1995-04-18
Abstract: FIELD: preparation of materials contaminated with radionuclides to long-time storage. SUBSTANCE: radioactive materials, primarily highly radioactive waste, are covered with layers of high-melting dielectric materials, such as carbide or boron nitride, or silicon, using method of thermal decomposition of gas mixture from carbon and ammonia, nitrogen and boranes or silanes. Volume content V1 of impurities in total volume V2 of source thermally decomposed materials is 1≅(V1+V2)/V2≅1,001. Materials covered with high-melting dielectrics may be fused into glass, quartz, or ceramics in which case matrix mass m1 and fused material mass m2 are interrelated as 1.01 ≅(m1+m2)/m2≅100. Then treated contaminated materials are placed in hermetically sealed metal container whose walls are covered inside and outside with layers of carbide, boron nitride, or silicon. These layers should be applied under the same conditions as in covering contaminated material. Metal contained is placed in caset stone or diabase container and stored in room protected against environmental effects and provided with air and water cooling. Cooling medium temperature T1 in storage room and maximum temperature T2 outdoors relate as 1.1 ≅(T1+T2)/T2≅2. EFFECT: reliable isolation of radioactive materials from environment.