baber/WOPTO huggingface dataset:
Patent NZ-583848-A (NZ)
Title: Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
Inventor: DEMATTEI JOHN
IPC: A61P27/02
Filed: 2008-09-15
Abstract: Disclosed is N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide benzene sulfonate and N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide benzene sulfonate H2O. The compounds are used to treat CFTR-mediated diseases, cystic fibrosis, hereditary emphysema, COPD, dry-eye disease or Sjogren's disease.
Patent NZ-584345-A (NZ)
Title: Method for producing a thickener dispersion
Inventor: LEYRER REINHOLD J
IPC: C08F265/02
Filed: 2008-11-13
Abstract: A method of preparing an aqueous thickener dispersion from a monomer composition which comprises: (a) at least one ethylenically unsaturated carboxylic acid, and (b) at least one ethylenically unsaturated hydrophobic monomer, where (i) an at least partially polymerized pre-emulsion is prepared from 10 to 80% by weight of the monomer composition and (ii) the remainder of the monomer composition is added in its entirety to the at least partially polymerized pre-emulsion and a free-radical polymerization is initiated using a redox initiator system, wherein the ethylenically unsaturated hydrophobic monomer may be selected from C1-C9-alkyl (meth)acrylates, dienes, vinyl aromatics, (meth)acrylonitrile and mixtures thereof, and the ethylenically unsaturated carboxylic acid may be selected from acrylic acid, methacrylic acid, itaconic acid and maleic acid.
Patent NZ-586757-A (NZ)
Title: Novel formulation
Inventor: BIEDERMANN KIMBERLY
IPC: A01N25/02
Filed: 2009-01-14
Abstract: Disclosed is a sanitizing formulation comprising: I. An acidic polymer which comprises either a homopolymer of acrylic acid crosslinked with an allyl ether of pentaerythritol, sucrose or propylene, or comprises units -[-CR1R2-CR3R4-CR5.COOH.-CR6.COOH-]-. II. An anionic surfactant which is either sodium lauryl sulphate, sodium laureth sulphate and alpha-olefin sulphates. III. Citric acid; and IV. A liquid vehicle comprising water, ethanol or a mixture of the two. The formulation is used to neutralize viruses on a surface, particularly to sanitize human hands or skin.
Patent NZ-589846-A (NZ)
Title: Telescopic needle shield with interlock
Inventor: BRIMHALL GREG L
IPC: A61M5/32
Filed: 2009-03-12
Abstract: 589846 A needle tip shield 12 comprising an outer tube 22, an inner tube 24 at least partially disposed within and telescoping within an outer tube 22 of the needle shield, a barrier disposed on a proximal end of the inner tube 24 shaped and sized to prevent a needle feature of a needle from being drawn proximally through the barrier, the needle being telescopically moveable within the inner tube 24, a clip 26 disposed within the inner tube shaped and sized to prevent a needle tip 74 of the needle from being advanced distally through the clip 26 after the needle tip 74 is withdrawn proximally past the clip 26.
Patent NZ-591218-A (NZ)
Title: A shoe heel support device
Inventor: NAISMITH-BEELEY MARK
IPC: A43B3/16
Filed: 2009-08-03
Abstract: 591218 A shoe heel support device is disclosed. The device includes a resilient shoe heel engagement portion (13) attached to a ground contacting base portion (24). The resilient shoe heel engagement portion (13) includes at least three lobe portions spaced radially from one another defining a bore (19) for receiving a shoe heel (15). The dimension of the bore (19) is smaller than the heel and the lobes are mounted for resilient movement relative to the bore.
Patent NZ-592485-A (NZ)
Title: Public emergency notification and communications system
Inventor: BENNER GARY TREVOR
IPC: G08B1/08
Filed: 2011-04-27
Abstract: Disclosed is an emergency notification terminal (1) which comprises a static receiver unit. The static receiver unit includes a trigger signal receiver, at least one alert indicator (3), and a central control element (5) configured to receive a coded trigger signal from the trigger signal receiver (3). The coded trigger signal includes information on the geographical area targeted by the coded trigger signal. The central control element (5) stores information on the geographical location of the terminal (1). The control element (5) compares the geographical target of the coded trigger signal with the geographical location of the terminal (1) and actuates the at least one alert indicator (3) on receipt of at least one coded trigger signal targeted at the geographical location of the terminal (1).
Patent NZ-596972-A (NZ)
Title: Production of adipic acid and derivatives from carbohydrate-containing materials
Inventor: JIANG HONG
IPC: C07C29/147
Filed: 2010-06-11
Abstract: 596972 Disclosed herein are processes for the chemocatalytic conversion of a glucose source to an adipic acid product of formula II wherein R1 and X are defined in the specification. The process comprises reacting a hydrodeoxygenation substrate of formula I, such as glucaric acid, and hydrogen gas in the presence of a hydrodeoxygenation catalyst and a halogen source. In one embodiment the hydrodeoxygenation catalyst comprises a first metal selected from Ru, Rh, Pd, Pt, and combinations thereof and a second metal selected from Mo, Ru, Rh, Pd, Ir, Pt, and Au. Additionally disclosed are products produced from the adipic acid products and processes for the preparation thereof.
Patent NZ-598064-A (NZ)
Title: Benzazepine derivatives useful as vasopressin antagonists
Inventor: TOMOYASU TAKAHIRO
IPC: A61K31/55
Filed: 2008-06-26
Abstract: 598064 Disclosed is a banzazepine compound of formula (I) where R1 is a C=O (CH2)n-COR2 group. The core structure is { 7-Chloro-1-[2-methyl-4-{ 2-methyl-benzoylamino)-benzoyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl} . Also disclosed is a pharmaceutical composition comprising a compound of formula (I). Further disclosed is the use of a compound of formula (I) in the manufacture of a medicament for the prevention or treatment of hypertension, edema, abdominal dropsy, heart failure, renal dysfunction, syndrome of inappropriate secretion of vasopressin (SIADH), liver cirrhosis, hyponatremia, hypokalemia, diabetes, circulatory insufficiency, or polycystic kidney disease (PKD).
Patent NZ-598222-A (NZ)
Title: Rain shield for use when accessing a vehicle comprising means to temporarily engage a vehicle surface
Inventor: HITT SARAH TENNELLE
IPC: B60J7/00
Filed: 2012-02-14
Abstract: Disclosed is a rain shield (1) made of waterproof, flexible sheeting designed to shelter a person (50) accessing the interior of a vehicle through a door (104). The rain shield has attachment means, for example magnets (8), arranged at an edge portion (6A) of the sheeting, which is adherently engageable with a surface (101) of a vehicle to effect temporary attachment of the rain shield to the surface. By attaching the sheet to the vehicle, the sheeting may overlie an area (102) adjacent an opening into the vehicle to shelter a person standing in the area who is accessing an interior of the vehicle through the opening. The rain shield further has at least one opening through which digits of the person's hands are receivable such that the person can manipulate the edge portion to bring about the attachment to the vehicle.
Patent NZ-598636-A (NZ)
Title: Systems, methods, and apparatuses for determining power usage with a meter
Inventor: REE BRADLEY RICHARD
IPC: G01R21/00
Filed: 2012-03-07
Abstract: Disclosed is a utility meter (205) with at least one communications interface (236) for communicating with a home area network. The meter (205) also includes a processor (232) in communication with the at least one communications interface (236). The processor (232) is configured to receive or transmit, via the at least one communications interface (236), information having a source or destination associated with the home area network. The processor (232) is further configured to determine that the information is attributable to activity chargeable to a customer associated with the home area network. The processor (232) is configured to then update a customer usage amount based upon the determination that the information is attributable to the activity chargeable to the customer.
Patent NZ-603060-A (NZ)
Title: Mesh Skylight guard shaped to have a pair of upright sides joined by a substantially planar mid section
Inventor: SCARLETT ROBERT MARK
IPC: E04D13/03
Filed: 2012-10-17
Abstract: Roof safety means comprising a mesh fitted over a skylight, the mesh formed and arranged so that in the event that a person steps firmly on the mesh it will support the weight of the person and prevent the person from falling through the roof. The mesh is shaped to have a pair of upright mesh sides joined by a substantially planar mid portion of mesh spanning such sides.
Patent NZ-603727-A (NZ)
Title: Flexible member and method for its manufacture
Inventor: HERDMAN JEFFREY STEWART
IPC: E01F9/627
Filed: 2011-05-19
Abstract: 603727 A flexible member for use in a marker post, wherein the member is substantially elastically bendable about one or more axes and includes a laminate formed by bonding together under heat and pressure an assembly of layers including at least one layer comprising uncured, wire reinforced elastomeric material.
Patent NZ-617590-A (NZ)
Title: Use of sigma ligands in diabetes type-2 associated pain
Inventor: VELA HERNÁNDEZ JOSÉ MIGUEL
IPC: A61P25/02
Filed: 2012-05-18
Abstract: The disclosure refers to the use of a sigma ligand, particularly a 1-aryl-3-aminoalkoxy pyrazole sigma ligand of formula (I) to prevent for treatment of type-2 diabetes-associated pain and related symptoms. Sigma ligands which may be used include the sigma 1 receptor antagonist 4-{ 2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl} morpholine (aka S1RA). The type-2 diabetes-associated pain and related symptoms may include pain derived from diabetic neuropathy, diabetic retinopathy, diabetic amyotrophy, gastroparesis, diabetic diarrhea, charcot joint, neuropathy of the bladder, diabetic nephropathy and/or diabetic foot problems.
Patent NZ-627600-A (NZ)
Title: Locking threaded fastener
Inventor: CAMPAU DANIEL N
IPC: F16B39/20
Filed: 2012-12-21
Abstract: A locking fastener includes a fastener body (42), a locking band (44) within the fastener body, and a retainer (96) secured to the fastener body to retain the locking band within the fastener body. The locking band includes first and second tangs (72, 74, figure 4) that fit within recesses (62, 64, figure 3) in the fastener body to limit angular movement of the tangs. The tangs and the recesses are dimensioned to control the torque required to remove the fastener from a threaded member. The retainer defines a central circular hole corresponding to the diameter of a threaded member on which the fastener is mounted.
Patent NZ-701757-A (NZ)
Title: Optimized synchronous generator of a gearless wind power plant
Inventor: GUDEWER WILKO
IPC: H02K19/16
Filed: 2013-05-22
Abstract: The invention concerns a synchronous generator of a gearless wind power installation. Such high power level wind power installations require synchronous generators with a large air gap diameter. However the generator diameter cannot be increased as desired due to transport conditions and installation costs. The invention seeks to provide a synchronous generator of a gearless wind power installation including an external rotor member and a stator, wherein the synchronous generator having a generator outside diameter and the stator has a stator outside diameter and a ratio of the stator outside diameter to the generator outside diameter is between 0.86 and 0.94, is separately excited, wherein the stator has radial cooling passages for radially supplying cooling air from the inside and has axial cooling passages for axially guiding the radially supplied cooling air for cooling the stator such that the radially supplied cooling air is passed through a stator lamination assembly and/or through stator winding assemblies; or that the radially supplied cooling air is divided up and passed axially in a forward direction and in a rearward direction, wherein an air gap is provided between the external rotor member and the stator, and the external rotor member has cooling openings towards the air gap so that a part of the cooling air flows from the air gap further outwardly through the external rotor member and between rotor member pole shoes of the external rotor member, along exciter windings of the external rotor member in order thereby to cool their exciter windings. Advantageously, the cooling allows the excited coils to be more compact which allows the stator outside diameter to generator outside diameter to be higher whilst maintaining a generator external diameter that is transportable.
Patent NZ-703077-A (NZ)
Title: Juicer
Inventor: KIM YOUNG KI
IPC: A47J19/06
Filed: 2013-06-27
Abstract: The present invention relates to a juicer in which: a driving shaft hole having a driving shaft inserted therein is formed on the lower part of a rotary brush, which is mounted between an inner wall of a housing and an outer wall of a net drum and has opened upper and lower surfaces and has a net brush for brushing the outer wall of the net drum, so that the driving shaft hole is rotationally mounted on a body; and a screw is arranged inside the net drum and has a screw spiral formed on the outer surface thereof, wherein a screw coupling protrusion or a screw coupling groove is formed on the upper part of the screw and a rotary brush coupling groove or a rotary brush coupling protrusion is formed on the upper part of the rotary brush such that the screw coupling protrusion and the rotary brush coupling groove are coupled or the screw coupling groove and the rotary brush coupling protrusion are coupled in such a manner that the rotary brush is directly rotated by the screw during the rotation of the screw, thereby reducing a failure rate caused by damage to or wearing down of components such as gears and the like and providing a simple and easy assembling operation.
Patent NZ-712345-A (NZ)
Title: Composition of macrocyclic lactones, levamisole, an amino sugar and an additional antiparasitic agent
Inventor: DE ROSE GUY FRANCIS
IPC: A61P33/00
Filed: 2014-04-10
Abstract: The present invention is directed to stabilized injectable compositions comprising at least one macrocyclic lactone, or derivative thereof, in combination with levamisole, and an amino sugar stabilizing agent, wherein the stabilizing agent prevents the degradation of the macrocyclic lactone from acid hydrolysis when combined with levamisole; optionally an additional antiparasitic agent, and a method for treating or controlling a parasitic infection or infestation in an animal by administering said composition.
Patent NZ-713718-A (NZ)
Title: Benzimidazole derivatives as bromodomain inhibitors
Inventor: JIANG ROBERT H
IPC: C07D417/14
Filed: 2014-05-08
Abstract: This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, and R5 are described herein.
Patent NZ-713973-A (NZ)
Title: Container
Inventor: SCHENNUM STEVE
IPC: A24F40/95
Filed: 2014-05-29
Abstract: A container including an elongate electronic nicotine delivery system or other flavoured vapour delivery system, the container comprising: a rigid elongate body defining a chamber including an end having an opening, an elongate electronic nicotine delivery system or other flavoured vapour delivery system inserted into the chamber through said opening and supported in an upright position within the chamber, a lid pivotally attached to said body to cover said opening in a closed position, an over-centre biasing mechanism configured to bias the lid toward a closed position until the lid has been pivoted into an intermediate position, beyond which the lid is biased towards an open position, a switch for detecting whether the lid is in an open or closed position, wherein the switch is mechanically operated by movement of the lid for detecting whether the lid is in an open or closed position, and electronic and/or electrical functionality which is controlled in accordance with the open or closed position of the lid as detected by the switch.
Patent NZ-716102-A (NZ)
Title: Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
Inventor: HIGH KATHERINE A
IPC: C12N7/01
Filed: 2014-07-22
Abstract: The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 and related AAV vectors target polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.
Patent NZ-719934-A (NZ)
Title: Compositions and methods vectors for inducing an enhanced immune response using poxvirus vectors
Inventor: HAUSMANN JÜRGEN
IPC: C12N15/86
Filed: 2014-11-25
Abstract: Provided herein are recombinant poxviruses comprising native nucleic acids specifying excess double-stranded RNA (dsRNA) early in infection, wherein the nucleic acids generating dsRNA comprise sequences encoding partially or completely complementary RNA transcripts, wherein the complementary portions of the RNA transcripts or the complementary RNA transcripts overlap by 100 or more nucleotides and the expression of the sequences encoding complementary RNA transcripts are directed by heterologous early or immediate early poxviral promoters. The poxviruses may further comprise heterologous nucleic acids encoding one or more costimulatory molecules, and/or heterologous nucleic acids encoding one or more infectious disease-associated antigens or tumor-associated antigens, as well as pharmaceutical compositions comprising such recombinant poxviruses and methods and uses thereof. The recombinant poxviruses provided herein enhance innate and adaptive immune activation in subjects compared to identical recombinant poxviruses lacking heterologous or native transcription units specifying excess early dsRNA.
Patent NZ-742679-A (NZ)
Title: Thermal conditioning device for an injection system
Inventor: CHASSOT PIERRE
IPC: A61M5/172
Filed: 2016-12-21
Abstract: The injection of fluids into patients is commonplace in several medical procedures. For example, a contrast agent may be injected to enhance contrast of body features in scan examinations. An injection system is usually used to pressurise and inject the contrast agent into the patient under predetermined injection conditions. Since contrast agents typically have a relatively high viscosity, the viscosity of the contrast agent may adversely affect its correct injection in the patient and requires the application of relatively high pressure which may be uncomfortable for the patient. The viscosity be reduced by increasing temperature of the contrast agent such as by pre-warming before injection using dedicated equipment separated from the injection system. However, the contrast agent cools quickly and some injection systems are unable to maintain the target temperature of the contrast agent for the entire scan examination. A solution for injecting one or more fluids into a patient is proposed. An injection system comprises one or more supply stations each one for supplying one of the fluids to be injected from a container, where at least one of the supply stations comprises housing means defining a chamber for housing the container, the chamber having a connection port for connecting the container to a delivery arrangement for delivering the fluid to the patient, and a conditioning device for thermally conditioning the fluid in the chamber. The conditioning device comprises a first conditioning element arranged around the connection port and a second conditioning element extending transversally to the first conditioning element. The use of first and second conditioning elements significantly improves performance of the injection system as it allows medical fluid to be maintained at the target temperature efficiently.
Patent NZ-753873-A (NZ)
Title: Colonic organoids and methods of making and using same
Inventor: WELLS JAMES
IPC: C12N5/00
Filed: 2017-12-05
Abstract: Disclosed herein are methods for the in vitro differentiation of a precursor cell into definitive endoderm, which may further be differentiated into a human colonic organoid (HCO), via modulation of signaling pathways. Further disclosed are HCOs and methods of using HCOs, which may be used, for example, for the HCOs may be used to determine the efficacy and/or toxicity of a potential therapeutic agent for a disease selected from colitis, colon cancer, polyposis syndromes, and/or irritable bowel syndrome. In a specific embodiment the inventions is a method of inducing formation of a human colon organoid (HCO), comprising the steps of a. contacting definitive endoderm (DE) with an FGF signaling pathway activator and a WNT signaling pathway activator for a period of time sufficient for said DE to form a mid-hindgut spheroid; b. contacting the mid-hindgut spheroid of step (a) with a BMP activator and an EGF signaling pathway activator for about 1 day to about 3 days; and c. contacting the mid-hindgut spheroid of step (b) with the EGF signaling pathway activator without a BMP activator for a period of time sufficient to form said human colon organoid, wherein said human colon organoid expresses SATB2. Preferably, the FGF signaling pathway is preferably activator is FGF4, the WNT signaling pathway activator is CHIR99021 and the BMP activator is BMP2.
Patent NZ-754169-A (NZ)
Title: Apoptosis signal-regulating kinase inhibitor
Inventor: NOTTE GREGORY
IPC: A61K31/4439
Filed: 2013-01-24
Abstract: Disclosed is a dosage unit comprising selonsertib (5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide) and its use as an apoptosis signal-regulating kinase inhibitor for the treatment of kidney fibrosis, liver fibrosis, lung fibrosis, diabetic nephropathy or diabetic kidney disease. Also disclosed are the two intermediates 5-(4-cyclopropy1-1H-imidazol-1-y1)-2-fluoro-4-methylbenzoic acid and 6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine used in the preparation of said compound Selonsertib.
Patent NZ-754652-A (NZ)
Title: Improvements in the synthesis of phycocyanins
Inventor: BRAIN CHELSEA MARIE
IPC: A23L29/269
Filed: 2015-01-27
Abstract: Culture of cyanobacteria in order to harvest the blue-green pigment phycocyanin in outdoor ponds results in poor yield and biological contaminants. The invention discloses systems for culturing microorganisms under red light (optimum emission wavelength between 670 nm and 720 nm) that result in increased cellular and media concentrations of the biological pigment compared with the same microorganism cultured under white light. The invention has applications in use as a natural food colouring, as antioxidants in the food supplement industries, in the nutraceutical, pharmaceutical, and cosmeceutical industries, and a non-toxic ink. The method results in pigment that is relatively easy to separate from the microorganism culture.
Patent PT-100476-A (PT)
Inventor: ARMITAGE BERNARD JOHN
IPC: A61K31/192
Filed: 1992-05-12
Abstract: The use of S(-)sodium 2-(4-isobutylphenyl)-propionate (the sodium salt of S(+)-ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphenyl)-propionate dihydrate.Processes to prepare S(-)sodium 2-(4-isobutylphenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.