baber/WOPTO huggingface dataset:
Patent RU-2745738-C1 (RU)
Title: One-reactor method for obtaining an antibody-drug conjugate intermediate product
Inventor: YUJ CHZHAOSIN
IPC: C07K5/00
Filed: 2020-02-13
Granted: 2021-03-31
Abstract: FIELD: biotechnology.  
     SUBSTANCE: invention relates to the field of biotechnology. A group of inventions is described, including a one-pot method for preparing an intermediate product of an antibody-drug conjugate, where the intermediate product of an antibody-drug conjugate is Py-MAA-Val-Cit-PAB-D or MC-Val-Cit-PAB-D, the use of the above a method in the preparation of an antitumor drug; and the use of the above method in the preparation of an antibody-drug conjugate. In one embodiment, the method comprises reacting Py-MAA-Val-Cit-PAB-OH or MC-Val-Cit-PAB-OH with bis (4-nitrophenyl) carbonate (NPC) in the presence of an organic base with the further addition of organic base and adding 1-hydroxybenzotriazole and drug part D to the reaction system.  
     EFFECT: invention expands the arsenal of methods for obtaining intermediate products of the antibody-drug conjugate.  
     9 cl, 1 dwg, 1 tbl, 6 ex
Patent RU-2746645-C1 (RU)
Title: Method for sampling alveolar air samples
Inventor: NEVMERZHITSKIJ VASILIJ IVANOVICH
IPC: G01N1/22
Filed: 2020-06-26
Granted: 2021-04-19
Abstract: FIELD: medicine. 
     SUBSTANCE: invention relates to medicine, namely to non-invasive methods of medical diagnostics, in particular the diagnosis of diseases by analyzing the composition of the air exhaled by the patient. The method includes placing the tubule through an open fitting of a sealed bag into a sealed bag, exhaling to the end of the alveolar air through the tube into the inside of the sealed bag until it is filled, removing the tubule from the sealed bag, closing the fitting of the sealed bag. In this case, the outer diameter of the tube is less than the inner diameter of the nozzle of the sealed bag, the outer wall of the tube and the inner wall of the nozzle form a through annular gap, and the area of the inner flow section of the tube is larger than the cross-sectional area of the ring formed by the outer diameter of the tube and the inner diameter of the nozzle of the sealed bag.  
     EFFECT: simplification and improvement of filling efficiency. 
     4 cl, 2 dwg
Patent RU-2744058-C1 (RU)
Title: Manufacturing method of wedge-shaped radar-transparent front fairing of supersonic aircraft body
Inventor: Vdovichenko Andrej Gennadevich
IPC: B64C1/36
Filed: 2020-06-26
Granted: 2021-03-02
Abstract: FIELD: aviation. 
     SUBSTANCE: invention relates to heat-resistant elements of a body of a supersonic aircraft (AC), in particular to a front fairing of its body, which is an antenna shell, radiating elements of which do not have a direct mechanical connection with the shell. Method of making wedge-shaped radar-translucent front fairing of supersonic airframe hull consists in production of fairing parts from radiotransparent heat-resistant composite material, including upper convex and lower flattened shells, which are equipped in their peripheral parts with mating surfaces and places for installation of elements of their attachment to each other, and elements of their attachment to each other, includes fabrication of multilayer fabric packages from heat-resistant thread, their impregnation with thermoactive binder, forming packages on mandrels with curing of binder, machining of docked surfaces of fairing parts, application of heat-resistant adhesive on jointed surfaces of shells and places for installation of elements of their fixation between each other, assembly, gluing of parts of fairing and smoothing of external surfaces of shells of fairing using heat-resistant putty. Multilayer tissue package of the upper convex shell is made of voluminous braided yarn. Upper convex shell is made so that it is formed by the lower end surface of the peripheral section of the lower outer surface of the fairing, and its joint surface is made on the side inner surface. Lower flattened shell is made with increased relative to upper convex shell thickness, using fabric layers from heat-resistant thread of flat braiding and equipped with facilitating sampling of composite material made in central part from side of inner side surface. Its mating surface is made on the upper end face, with formation of its outer side surface, when gluing the cowl covers, central area of lower outer surface of fairing, and place for installation of attachment elements in shells are made after their gluing along mating surfaces, with removal of leading convex shell from front edge, in area of increased thickness of peripheral part of lower flat shell. 
     EFFECT: production of wedge-shaped radio-transparent front fairing of supersonic airframe hull with extended operation time. 
     4 cl, 2 dwg
Patent RU-2748136-C1 (RU)
Inventor: Kotov Mikhail Altaevich
IPC: G01M9/00
Filed: 2020-07-02
Granted: 2021-05-19
Abstract: Изобретение относится к области экспериментальной аэродинамики, в частности к аэродинамическим трубам и к импульсным газодинамическим установкам типа ударных труб, позволяющим реализовывать экспериментальное моделирование условий полета высокоскоростных летательных аппаратов в верхних слоях атмосферы и в космическом пространстве. Сопловой блок состоит из сменных и стационарных секций, при этом стационарные секции представляют собой фланцы с торцевой гайкой, плоскость стенки которой перпендикулярна направлению распространения набегающего потока в камере низкого давления ударной трубы, а сменная секция - непосредственно профилированное сопло, которое закреплено между фланцами. Входное сечение профилированного сопла находится в отсеке формирования набегающего потока, выходное сечение располагается в рабочей секции, а на внешней стороне сопла выполнен выступ по всему сечению. На фланцах выполнены симметрично расположенные отверстия для фиксации соплового блока, а между торцевой гайкой и профилированным соплом расположена диафрагма. Профилированное сопло выполняется из полимерного материала методом 3D-печати. Технический результат заключается в расширении арсенала технических средств, возможности создавать набегающий на исследуемую модель поток с конкретным распределением газодинамических параметров и обеспечивать снижение трудо- и материалозатрат на производство сопел. 4 з.п. ф-лы, 6 ил.
Patent RU-2744475-C1 (RU)
Title: Цифроаналоговый преобразователь
Inventor: KOZHEVNIKOV ALEKSEJ ALEKSANDROVICH
IPC: H03M1/66
Filed: 2020-08-05
Granted: 2021-03-10
Abstract: Изобретение относится к области автоматики, информационно-измерительной и вычислительной техники, и может быть использовано для преобразования модулярного и позиционного кода в аналоговый электрический сигнал. Технический результат заключается в обеспечении возможности формировать аналоговый эквивалент входной цифровой величины, заданной как в модулярном, так и позиционном представлении. Сущность изобретения сводится к промежуточному преобразованию цифрового модулярного или позиционного кода в дискретно-фазированную форму представления чисел в системе остаточных классов с дальнейшим переходом к выходному аналоговому эквиваленту в виде тока или напряжения. 2 ил.
Patent RU-2758092-C1 (RU)
Title: ANTIBODY TO IL-4Rα AND APPLICATION THEREOF
Inventor: XU ZHENG
IPC: A61P37/00
Filed: 2018-02-01
Granted: 2021-10-26
Abstract: FIELD: biochemistry.SUBSTANCE: invention relates to the field of biochemistry, in particular to an antibody or an antigen-binding fragment thereof specifically binding to the human interleukin-4 receptor α(hIL-4Rα), the method for production thereof, and to a composition and set containing the antibody. Also disclosed is an isolated nucleic acid molecule encoding the above antibody or the antigen-binding fragment thereof, as well as a vector and a host cell containing the molecule.EFFECT: invention provides a possibility to effectively prevent or treat a disease or disorder associated with IL-4/IL-4Rα signalling in the human body.15 cl, 4 dwg, 1 tbl, 5 ex
Patent RU-2747768-C1 (RU)
Inventor: Iagafarov Albert Salavatovich
IPC: E21B33/12
Filed: 2020-09-18
Granted: 2021-05-13
Abstract: Изобретение относится к нефтегазодобывающей промышленности, а именно к устройствам для изоляции зон водопритоков при эксплуатации нефтяных скважин, в том числе с зонами различной проницаемости в боковых и горизонтальных стволах. Устройство для разобщения пласта горизонтальной скважины включает соединенные продольно-гофрированные трубы с герметизирующими элементами, замкнутыми по периметру трубы, верхний и нижний цилиндрические участки. Нижний цилиндрический участок снабжен башмаком с клапаном, а верхний - посадочным переводником с резьбой для соединения с колонной труб. Верхний цилиндрический участок с посадочным переводником снабжен также верхним и нижним пуансонами. Верхний пуансон выполнен подвижным относительно посадочного переводника и взаимодействующим с верхней завальцовкой верхнего цилиндрического участка при создании давления в посадочном переводнике. Нижний пуансон выполнен неподвижным относительно посадочного переводника и взаимодействующим с нижней завальцовкой верхнего цилиндрического участка. Кроме того, посадочный переводник снабжен седлом под шар и отверстием. Башмак установлен в нижний цилиндрический участок с завальцовкой и выполнен из цементно-бетонной смеси и с возможностью выхода из нижнего цилиндрического участка при создании определенного давления. При этом давление выхода башмака ниже, чем давление выхода верхнего пуансона. Предлагаемое устройство надежно в работе, позволяет устанавливать его в горизонтальных скважинах, в том числе несколько устройств для разделения горизонтального ствола на несколько участков, и удалять башмак с одновременным его разрушением без применения специальных технических средств. 1 ил.
Patent RU-2742533-C1 (RU)
Inventor: SZU-NAN YANG
IPC: H01M10/0562
Filed: 2020-10-15
Granted: 2021-02-08
Abstract: FIELD: electrochemical systems. 
     SUBSTANCE: invention relates to an electrolyte of a layered structure of an electrochemical system, in particular to a material for adapting a contact surface for solid electrolytes and a corresponding composite electrolyte system. The material for adapting the contact surface is mainly composed of a polymeric base material that allows metal ions to move within the material, and an additive that separates the metal salts and acts as a plasticizer. A contact surface adaptation material is applied to the surface of solid electrolytes to create a surface-to-surface transfer mode. 
     EFFECT: technical result is elimination of the problem of high resistances caused by direct contact of solid electrolytes.  
     22 cl, 23 dwg
Patent RU-2755085-C1 (RU)
Title: Method for production of organic peroxides or peroxicetals
Inventor: Aristov Andrej Vyacheslavovich
IPC: C07C407/00
Filed: 2020-10-26
Granted: 2021-09-13
Abstract: FIELD: chemical industry.  
     SUBSTANCE:  present invention relates to a method for producing organic peroxides or peroxicetals, consisting in the interaction of hydroperoxide and alcohol, or olefin, or ketone using a catalyst representing a mixture consisting of molded poly sulfonic acid on polypropylene, a mixture of arylsulfonic acids and water of the following composition, wt. % of the catalyst: molded poly sulfonic acid on polypropylene 1-50, a mixture of arylsulfonic acids 1-75, water up to 100.  
     EFFECT: invention makes it possible to obtain target products with high yield and selectivity.  
     1 cl, 1 tbl, 17 ex
Patent RU-2767389-C1 (RU)
Title: Method for precise landing of unmanned aerial vehicle of airplane type and device for its implementation
Inventor: VOLOBUEV MIKHAIL FEDOROVICH
IPC: B64C39/02
Filed: 2020-11-18
Granted: 2022-03-17
Abstract: FIELD: aviation. 
     SUBSTANCE: group of inventions relates to a method and a device for the precise landing of an unmanned aerial vehicle (hereinafter – UAV) of an airplane type. To land the UAV, it is withdrawn in the direction of a landing site in a certain way, an anchor is lowered from the UAV using an anchor cable, engine speed of the UAV is lowered to reduce speed, and the UAV is flown at the minimum permissible speed until the anchor engages with a hooking device, when the anchor engages with the hooking device, a parachute is released, and the engine is turned off, after the anchor engages with the hooking device and the parachute is opened, the UAV is pulled by the anchor cable coupled with the anchor with the hooking device in the direction of a pre-stretched horizontal grid at the landing site of the UAV, the UAV is landed on the stretched grid. The device contains onboard equipment and landing equipment. Onboard equipment contains a parachute, a parachute ejection device, an onboard coil with an anchor cable and an anchor fixed at the end of the cable, a cable lowering device. Landing equipment contains a landing pad with racks installed vertically on it, a grid stretched on a frame and having a hole, two flexible poles, a device for rewinding anchor cable, a winch, a launcher, pole removing mechanisms, a landing cable.  
     EFFECT: UAV landing safety is improved; UAV reuse efficiency is increased. 
     2 cl, 2 dwg
Patent RU-2757658-C1 (RU)
Title: Suspension for electroplating coatings on ferromagnetic parts
Inventor: GORBUNOV SERGEJ VLADIMIROVICH
IPC: C25D17/06
Filed: 2020-12-16
Granted: 2021-10-19
Abstract: FIELD: plating industry.  
     SUBSTANCE: invention relates to the field of electroplating and can be used for local application of electroplating coatings on small-sized products made of ferromagnetic materials, in particular on the contact parts of reed switches. The suspension contains a magnetic system, as well as a flat base with a thickness of 1.0-2.0 mm and two identical flat perforated plates with coaxial holes of circular cross-section, located in parallel at a fixed distance from each other and made of non-magnetic material, and a permalloy foil with a thickness of 50.0-100.0 mcm is located on the surface of the central part of the base in contact with the parts.  
     EFFECT: improving the quality of electroplating of contact parts of reed switches.  
     1 cl, 1 dwg, 1 tbl
Patent RU-2755021-C1 (RU)
Title: Generator hybrid switch
Inventor: Lavrinovich Valerii Aleksandrovich
IPC: H01H33/00
Filed: 2021-02-17
Granted: 2021-09-09
Abstract: FIELD: electrical engineering. 
     SUBSTANCE: invention relates to electrical engineering, namely to high-voltage electrical equipment engineering and can be used in the development of high-voltage generator switches. The generator hybrid switch, high-voltage, built into the shielding current line, contains the main current line with disconnectors separating the generator switch from the generator on the one hand and from the network that the generator feeds, on the other hand, the main contacts, arc-extinguishing contacts, earthing devices, a control system with a starting unit and current sensors. A voltage sensor and two current lines are connected to the main current line in parallel to the main contacts. The first current line contains a vacuum arc-extinguishing chamber and a current sensor connected in series. The second current line according to the first version contains a vacuum controlled spark gap and a current sensor. According to the second version, the second current line contains a thyristor assembly and a current sensor. The outputs of all current sensors of the generator hybrid switch are connected to the inputs of the control system, providing control of the drives. On the main current line, a current-limiting fuse is connected in series with the main contacts, which includes an additional autonomous control system that operates at an instantaneous current value of the generator hybrid switch exceeding the pre-set value of the work current. An additional autonomous control system is connected to an additional current sensor installed on the main current line and located under its potential.  
     EFFECT: increase in the resource and reliability of the generator hybrid switch.  
     2 cl, 2 dwg
Patent RU-2756183-C1 (RU)
Title: Foliar fertilizer for growing food crops
Inventor: KARAKOTOV SALIS DOBAEVICH
IPC: A01N25/00
Filed: 2021-03-02
Granted: 2021-09-28
Abstract: FIELD: agriculture.  
     SUBSTANCE: invention relates to agriculture, in particular to mineral fertilizers for foliar treatment of plants containing phosphoric and nitrogen components, as well as trace elements. Foliar fertilizer for growing food crops contains nitrogen-containing material, orthophosphoric acid, trace elements, namely magnesium and zinc compounds, auxiliary substances, the fertilizer additionally contains ethoxylated aliphatic (fatty) amine, with the following ingredient content, wt.%: nitrogen-containing material 0.1-40.0, orthophosphoric acid 1.0-60.0, magnesium compound 0.1-8.0, zinc compound 0.1-10.0, ethoxylated aliphatic (fatty) amine 0.01-6.0, excipients 0.01-6.0, water being the rest, up to 100%. Urea and/or monoethanolamine are used as nitrogen-containing material, their oxides, or phosphates, or sulfates, or chlorides, or nitrates are used as magnesium and zinc compounds, and ethoxylated sterialamine, or ethoxylated oleylamine, or ethoxylated cocoylamine, or ethoxylated thalloylamine, or ethoxylated alkylamine C 13 -C 15  is used as an ethoxylated aliphatic (fatty) amine.  
     EFFECT: proposed foliar fertilizer provides an improvement in the quality of fertilizer due to the use of surfactants, which reduce the surface tension and increases the wetting properties of the fertilizer, as well as increases the yield of agricultural crops.  
     4 cl, 4 tbl, 1 ex
Patent RU-2759634-C1 (RU)
Inventor: Kuzakov Daniil Aleksandrovich
IPC: F21V21/04
Filed: 2021-03-09
Granted: 2021-11-16
Abstract: Изобретение относится к области строительства и светотехники. Способ крепления осветительных приборов на натяжной потолок заключается в следующем. Закрепляют монтажную ленту на несущей поверхности. Закрепляют концы монтажной ленты в корпусе платформы. Для этого продевают узкие участки ленты в отверстия-прорези платформы до упора в стопоры ленты, а далее загибают узкие участки ленты. Устройство крепления включает в себя платформу с ребрами жесткости и центральным отверстием и пластину с узлами крепления к несущей поверхности. Края пластин, предназначенные для крепления к платформе, выполнены уже ширины основной части пластины. Платформа содержит отверстия-прорези в местах крепления пластин. Крепление пластин к платформе характеризуется размещением узкой части ленты в отверстии-прорези в платформе до упора в переходы узкой части пластины в основную с загибом выступающей части пластины. Достигается упрощение процесса установки и демонтажа. 2 н. и 3 з.п. ф-лы, 3 ил.
Patent RU-2755655-C1 (RU)
Inventor: VINOGRADOV ALEKSANDR VLADIMIROVICH
IPC: H02J13/00
Filed: 2021-03-09
Granted: 2021-09-20
Abstract: Изобретение относится к области электротехники, в частности к устройствам секционирования и резервирования линий электропередачи, и предназначено для коммутации, защиты электрической сети и оборудования мультиконтактной коммутационной системы от аварийных режимов работы и коммутационных и атмосферных перенапряжений, учета электроэнергии, контроля качества электроэнергии, контроля количества и времени отключения напряжения в распределительных электрических сетях трехфазного тока. Технический результат заключается повышении надёжности мультиконтактной коммутационной системы, уменьшении недоотпуска электроэнергии потребителям, повышении надежность и эффективность систем электроснабжения потребителей. Технический результат достигается за счет того, что мультиконтактная коммутационная система с двумя силовыми контактными группами, соединенными в общую точку, содержит один вводной и два выводных коммутационных элемента ручного управления, два коммутационных элемента дистанционного управления, два блока управления коммутационными элементами дистанционного управления, блок приёма и передачи данных, блок управления мультиконтактной коммутационной системой, блок бесперебойного питания, три ограничителя перенапряжения. 1 ил.
Patent RU-2758613-C1 (RU)
Title: Method for producing chromium-containing powders from steel x13 in butyl alcohol
Inventor: AGEEVA EKATERINA VLADIMIROVNA
IPC: C22C27/06
Filed: 2021-03-29
Granted: 2021-11-01
Abstract: FIELD: powder metallurgy. 
     SUBSTANCE: invention relates to powder metallurgy, in particular to methods for producing a powder that can be used for spraying corrosion-resistant coatings. Chromium-containing powder is obtained by electroerosive dispersion of X13 alloy in butyl alcohol at a voltage on the electrodes of 100-110 V, a capacity of 45 μF discharge capacitors and a pulse repetition rate of 65-75 Hz. 
     EFFECT: invention provides a powder with an average particle size of 49.33 mcm with low energy costs and environmental cleanliness of the process. 
     1 cl, 3 dwg, 3 ex
Patent RU-2769152-C1 (RU)
Title: Method for cultivation of microalgae chlorella vulgaris
Inventor: Svazlyan Gayane Agasovna
IPC: A01G33/00
Filed: 2021-05-18
Granted: 2022-03-28
Abstract: FIELD: biotechnology.  
     SUBSTANCE: invention relates to the field of biotechnology, in particular to methods for artificial cultivation of microalgae of the species Chlorella vulgaris. The method for cultivation of microalgae Chlorella vulgaris involves growing microalgae in a photobioreactor on a nutrient medium with aeration and mixing of layers under artificial lighting. Microalgae are grown in a photobioreactor with a wedge-shaped bottom, on a Tamiya nutrient medium with the addition of 0.01% ASD F-2 preparation, with constant aeration and stirring of the suspension using an aquarium pump and a compressor with simultaneous supply of 0.05 l/min carbon dioxide, at a temperature of 30°C and continuous illumination with 5000 Lux fluorescent lamps. The photobioreactor for growing microalgae has a rectangular cross-section, the distance between the large walls is 10 cm. The wedge-shaped bottom has ascending and descending parts, the angle between which, as well as the angles between each part and the adjacent vertical wall, are equal to 120°. The length of the working vertical wall connected to the descending part of the bottom is L, the projection of the descending part of the bottom on the horizontal base is 2/3 L, and the projection of the ascending part of the bottom on the horizontal base is 1/3 L. This bottom structure improves the mixing of the microalgae suspension.  
     EFFECT: increase in the growth of biomass and the preservation of the required quality with minimal time and energy costs, as well as the simplicity and accessibility of the method.  
     2 cl, 1 dwg, 6 tbl
Patent RU-2764303-C1 (RU)
Title: Liquid sprayer
Inventor: MARCHENKO LEONID ANATOLEVICH
IPC: A01M7/00
Filed: 2021-07-26
Granted: 2022-01-17
Abstract: FIELD: agriculture. 
     SUBSTANCE: sprayer comprises a cylindrical body (1), a cover (2), an inlet channel (3) connected with a conoidal nozzle (4), an injection mixing chamber (5), an outlet confuser (6), a cylindrical outlet channel (7), an annular air chamber (8) with a cylindrical channel (9) for air supply, radial channels (10), a deflector (11) with a dissecting edge (12) and deflecting surfaces (13 and 14). The injection mixing chamber (5) is made in the form of a spheroid with a small axis of rotation aligned with the axis of symmetry of the atomizer, and is equipped with air intake holes (17) made along the equatorial line. The chamber is connected with the conoidal confuser (6) in the lower part. The deflecting surfaces (13 and 14) are asymmetrical relative to the vertical axis of symmetry of the sprayer and are made in the form of a part of the surfaces of paraboloids of rotation (18 and 19). The angle of flow of the working fluid from one deflecting surface (13) is at least twice as great as the angle of flow of the working fluid from the other deflecting surface (14). 
     EFFECT: phytosanitary condition of agrocenoses and increase in the yields of crops are ensured. 
     1 cl, 3 dwg