baber/WOPTO huggingface dataset:
Patent EP-1104465-A1 (EP)
Inventor: GLUCKSMANN MARIA ALEXANDRA
IPC: A61K45/00
Filed: 1999-08-20
Abstract: La présente invention concerne un récepteur récemment identifié qui appartient à la superfamille des récepteurs couplés à la protéine G. Elle concerne également les polynucléotides codant pour ce récepteur. De plus, l'invention porte sur des méthodes d'utilisation des polypeptides et des polynucléotides de ce récepteur en tant que cible pour le diagnostic et le traitement de troubles induits par ce récepteur. Elle concerne également des procédés de criblage de médicaments qui font intervenir les polypeptides et les polynucléotides de ce récepteur dans le but d'identifier des agonistes et des antagonistes à des fins de diagnostic et de traitement. Elle concerne en outre les agonistes et les antagonistes basés sur les polypeptides et les polynucléotides de ce récepteur. Enfin, l'invention s'intéresse à des procédés permettant d'obtenir les polypeptides et les polynucléotides de ce récepteur.
Patent EP-1115450-A1 (EP)
Inventor: HANSEN HENRIK CHRISTIAN
IPC: A61M25/00
Filed: 1999-09-23
Abstract: A catheter se comprising a catheter and a package for storing of the catheter before use and for collecting or discharging urine, wherein an elongated part of the package forms a tube and wherein the catheter has a proximal part to be inserted into the urethra, a distal part in the form of a tubular section having an inner diameter at least as large as the inner diameter of the part of the proximal part of the catheter and a sealing part separating the proximal part of the catheter and the tubular distal part. The inventive shape of the catheter combined with the shape of the package prevents a blocking of the free flow of urine from the urethra into the package.
Patent EP-1112171-A1 (EP)
Inventor: MURPHY JAMES C
IPC: B29C70/44
Filed: 1999-09-13
Abstract: A process for fabricating a composite vessel includes the steps of: A) preforming (e.g., by winding fiber and at least one thermoplastic substance onto a thermoplastic liner) a thermoplastic shell which has at least one opening for access to the interior; B) extruding a circular cross section of a fluid parison of thermoplastic material (which preferably is chosen to have a melting point lower than that of the thermoplastic shell) into the interior of the thermoplastic shell through the opening; C) in a mold, applying at least one force (such as gas under pressure) which tends to urge the fluid parison toward the interior walls of the thermoplastic shell (which may be preheated prior to introduction into the mold) such that the fluid parison imparts heat to the thermoplastic shell; D) continuing step C) until the thermoplastic shell and the fluid parison consolidate to form a composite vessel; E) cooling the vessel until it is solidified; and F) removing the vessel from the mold. For some composite vessels, prior to step C), an insert may be introduced into the interior of the parison and positioned in alignment with the opening in the thermoplastic shell such that the insert is rendered integral with the composite vessel during step D). Suitable thermoplastic materials include polyethylene, polypropylene, polybutylene terephthalate and polyethylene terephthalate. The resulting composite vessel exhibits superior mechanical and aesthetic properties.
Patent EP-1121552-A1 (EP)
Inventor: TRICHARD CLAUDE
IPC: F16L11/14
Filed: 1999-10-14
Abstract: The invention concerns a connection device (11) for sealingly assembling two elements (1a, 1b) of an underwater installation conduit (1), comprising concentrically an inner sheath (2) and an outer sheath (10). The invention is characterised in that it comprises a fitting including a single-piece sleeve (13), whereof the internal passage is adapted to be externally shrunk on sealed to said sleeve two tips, respectively at the two ends of the inner sheath (2) of the two elements (1a, 1b) to be connected, stripped of the outer sheath (10), and comprises at said sleeve (13) two tips two threads in opposite direction respectively, said sleeve (13) comprising on the outside, in a median region, at least a flat section (12), adapted to be clamped by rotating the sleeve (13) with a wrench.
Patent EP-1135245-A1 (EP)
Inventor: GOEDICKE FRANZ
IPC: B29C48/43
Filed: 1999-11-03
Abstract: Method and device for reprocessing a thermoplastic polycondensate, in particular for the recycling of thermoplastic polycondensates, such as polyethylene terephthalate, polyester or polyamide is provided. The polycondensate is introduced into an extruder in a solid state. The polycondensate is then heated to a temperature below melting temperature and degassed or dried at below atmospheric pressure or with an inert gas added. Preferably, to prevent the polycondensate flakes from escaping through a degassing opening, a conveying device is used to convey the escaping flakes back into the extruder. The dried flakes are then melted.
Patent EP-1126802-A1 (EP)
Inventor: HEATON KEITH PATRICK
IPC: A61F7/00
Filed: 1999-11-05
Abstract: An enclosure is described for containing a patient whose core temperature is to be cooled below normal body temperature, e.g. to reduce brain damage in patients suffering cardiac arrest. The enclosure comprises a base panel and one or more side panels attached to the base panel, the side panels being foldable over the patient to create an enclosure. Air conduits are provided on one or more panels with outlets positioned to direct cold air onto areas of the patient from which heat loss is particularly rapid.
Patent EP-1135827-A1 (EP)
Inventor: SENGUPTA LOUISE
IPC: H01P3/16
Filed: 1999-10-15
Abstract: Une structure diélectrique accordable comprend une première couche de matériau diélectrique, une seconde couche de matériau diélectrique positionnée adjacente à la première couche de matériau diélectrique, la seconde couche de matériau diélectrique ayant une constante diélectrique inférieure à celle de la première couche de matériau diélectrique, ainsi que des électrodes destinées à appliquer une tension régulable au premier matériau diélectrique, régulant ainsi une constante diélectrique du premier matériau diélectrique, au moins une des électrodes étant positionnée entre les première et seconde couches de matériau diélectrique. Les matériaux diélectriques peuvent présenter diverses formes et être assemblés selon des orientations variées l'un par rapport à l'autre. La structure diélectrique accordable est utilisée dans divers dispositifs parmi lesquels des câbles coaxiaux, des antennes à cavité, des lignes de microrubans, des lignes coplanaires et des guides d'ondes.
Patent EP-1140980-A1 (EP)
Title: Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same
Inventor: GARBAY CHRISTIANE
IPC: C07K5/08
Filed: 1999-12-24
Abstract: The invention concerns a compound corresponding to general formula (I) wherein, in particular: R2 represents a phenylmethyl or naphthylmethyl or cyclohexylmethyl radical, 2- and 3-pyridinylmethyl, substituted on the cycle in meta or para position by an acid group or an alkyl radical of the type (CH2)n (with n = 3 or 4) substituted in terminal position by an acid group; and R3 represents a hydrogen group or a linear or branched C1-C4 alkyl or alkylcycloalkyl with a C3-C6 cycloalkyl. The invention also concerns the use of a compound of general formula (I) for preparing a pharmaceutical composition for treating diseases related to proliferative processes, cancers and/or metastases.
Patent EP-1140860-A1 (EP)
Inventor: BRADBURY ROBERT HUGH
IPC: C07D403/12
Filed: 1999-12-20
Abstract: A pyrimidine derivative of formula (I): wherein: R1 is an optional substituent as defined within; Rx is selected from halo, hydroxy, nitro, amino, cyano, mercapto, carboxy, sulphamoyl, formamido, ureido or carbamoyl or a group of formula (Ib): A-B-C- as defined within; Q1 and Q2 are independently selected from aryl, a 5- or 6-membered monocyclic moiety; and a 9- or 10-membered bicyclic heterocyclic moiety; and one or both of Q1 and Q2 bears on any available carbon atom one substituent of formula (Ia) as defined within; and Q1 and Q2 are optionally further substituted; or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof; are useful as anti-cancer agents; and processes for their manufacture and pharmaceutical compositions containing them are described.
Patent EP-1125101-A1 (EP)
Title: Sonde plage elevee pour manometre
Inventor: FERGUSON WALTER J
IPC: G01L7/02
Filed: 1999-10-12
Abstract: La présente invention concerne une sonde (12) destinée à capter des pressions d'un liquide à plages élevées, de l'ordre de 40.000 psi et plus. Elle comprend un tube d'une longueur prédéterminée dont une extrémité est fermée et qui, en l'absence de pression, présente une configuration rectiligne.
Patent EP-1219685-A1 (EP)
Inventor: FUKAGAWA RYOICHI
IPC: C09D127/12
Filed: 1999-10-04
Abstract: A thermosetting fluorine-containing resin powder coating
composition prepared by mixing a fine powder of silicon oxide having an
average particle size of 1/100 or less of that of a powder of fluorine-containing
resin powder coating composition in an amount of 0.01 to 5
parts by weight based on 100 parts by weight of the powder of fluorine-containing
resin powder coating composition. The thermosetting
fluorine-containing resin powder coating composition of the present
invention can be used as a coating composition in various fields where
weather resistance is required, and can protect a substrate, particularly
a metallic substrate sufficiently.
Patent FI-20176019-A1 (FI)
Title: Limited range source of electromagnetic radiation
Inventor: SEPPÄ SANTERI JEREMIAS
IPC: H01S3/10
Filed: 2017-11-15
Abstract: A source of electromagnetic radiation (100) configured to provide illumination, comprising a tunable source of electromagnetic radiation (10) comprising a tunable laser source with a small linewidth; and a control element (20) configured to tune the wavelength of the source of electromagnetic radiation (10) to a desired wavelength corresponding to an absorption line of an atom or a molecule or other species present in the medium through which the electromagnetic radiation is to propagate so that the range of the electromagnetic radiation in the medium is limited; wherein the control element (20) is configured to receive data relating to the desired wavelength; and wherein the electromagnetic radiation comprises visible or infrared light, further comprising an arrangement for determining the desired wavelength (110) configured to send data relating to the desired wavelength to the control element (20).
Patent FI-20185119-A1 (FI)
Title: Synthesis and purification of muconic acid ester from aldaric acid esters
Inventor: THOMAS DAVID
IPC: C07C69/602
Filed: 2018-02-09
Abstract: According to an example aspect of the present invention, there is provided a method for producing muconic acid ester from aldaric acid ester, and for separating and purifying the produced muconic acid ester by high vacuum distillation in a total heating environment.
Patent HK-1038047-A1 (HK)
Title: Vacuum tank construction.
Inventor: EDMONDSON LORNA K
IPC: E03D5/00
Filed: 2001-12-24
Abstract: A vacuum tank assembly includes a vacuum tank that has a low profile and will fit in small, and particularly low height, compartments of a boat or RV. The tank is connected to a vacuum toilet and a vacuum pump during use. The tank preferably has a generally rectangular prism configuration, and has a front surface in which openings for receipt of a dip tube assembly, sewage inlet (from the toilet), and vacuum switch are provided. The dip tube assembly includes an adaptor operatively connected to the vacuum pump and an evacuator component which has a generally tubular configuration and a substantially flat open bottom closely overlying the bottom interior of the tank. A locator tab cooperates with a cut out in the tank front surface to properly position the evacuator open bottom adjacent the tank bottom.   <IMAGE>
Patent HK-1044104-A1 (HK)
Title: Filter bag arrangement in electric vacuum cleaners and filter bag with holding plate
Inventor: PETER ARNOLD
IPC: A47L/
Filed: 2002-06-21
Abstract: An arrangement of a filter bag (35) in an electric vacuum cleaner is described. The filter bag possesses a retaining plate (36) that possesses an opening (38) for the entry of dust into the filter bag and has a section that can be deflected, assigned to the edge side. It can be deflected in the course of the insertion of the filter bag into the vacuum cleaner. The vacuum cleaner has an indicator (1) for the state of fill with an indicating piston (3). The indicating piston can be moved by the pressure difference on the filter bag and has a piston shaft (7) with a catch hook (11). The catch hook can be hooked on a housing wall below the penetration. The section that can be deflected, designed as a fastening section that has a free edge, is deflected upwards by the housing projecting upwards over the retaining plate and/or the catch hook.
Patent HK-1044175-A1 (HK)
Title: Ribonucleoprotein complex in paramyxovirus
Inventor: KITAZATO KAIO
IPC: C07K14/115
Filed: 2002-08-08
Abstract: A functional RNP containing negative-strand single-stranded RNA derived from Sendai virus, which has been modified so as not to express any envelope protein, has been successfully prepared. An RNP comprising a foreign gene is prepared and inserted into a cell with the use of a cationic liposome, thereby successfully expressing the foreign gene.
Patent HK-1046833-A1 (HK)
Title: Plug for a coffee-making apparatus and means for fastening such a plug
Inventor: JOERGENSEN CARSTEN
IPC: H01R13/05
Filed: 2002-11-27
Abstract: A plug for a power consumer is positioned centrally in a recess in a bottom of the power consumer and rests in a flange at an edge of the recess. The plug has a first portion and a second portion that can be rotated relative to each other about a common axis perpendicular to the bottom. The first portion of the plug has a plurality of fish plates extending outwardly from its sides, each fish plate having a recess. The second portion has a plurality of hooks, each having a protuberance. By rotation of the second portion relative to the first portion the protuberance of each hook is engaged in the recess of the respective corresponding fish plate.
Patent HK-1054381-A1 (HK)
Title: Substituted 2-(2,6-dioxo-3-fluoropiperidine-3-yl)-isoindolines and their use to reduce tnf-alpha levels
Inventor: MULLER GEORGE W
IPC: A61P29/00
Filed: 2003-09-15
Abstract: 1-Oxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines reduce the levels of inflammatory cytokines such as TNF alpha in a mammal. A typical embodiment is 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindoline.
Patent HK-1055992-A1 (HK)
Title: Dna transfection system for the generation of infectious negative strand rna virus
Inventor: HOFFMANN ERICH
IPC: C07K14/11
Filed: 2003-10-28
Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I -pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus. Attenuated or inactivated RNA viruses produced by the present invention may be administered to a patient in need of vaccination by any of several routes including intranasally or intramuscularly.
Patent HK-1057059-A1 (HK)
Title: Recombinant alpha-l-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
Inventor: HENSTRAND JOHN M
IPC: A61K38/43
Filed: 2003-12-22
Abstract: The present invention provides a recombinant human ±-L-iduronidase and biologically active fragments and mutants thereof, large scale methods to produce and purify commercial grade recombinant human, ±-L-iduronidase enzyme as well as methods to treat certain genetic disorders including ±-L-iduronidase deficiency and mucopolysaccharidosis I (MPS 1).
Patent HK-1065520-A1 (HK)
Title: Ultrasonic wave sealing method for container
Inventor: SHINOHARA MITSUHIKO
IPC: B65B51/22
Filed: 2004-10-26
Abstract: An ultrasonic wave sealing method for container for sealing a cover (12) on a container body (11) by using an ultrasonic horn (54) having a sealing action face (53), comprising the steps of, with a container body flange (24) overlapped with the outer peripheral edge part of the cover (12), pressurizing the overlapped part by the sealing action face (53) and acting an ultrasonic wave rotating vibration on the sealing action face (53) in the rotating direction about an axis parallel with a pressing direction.
Patent HK-1068078-A1 (HK)
Title: Subscriber unit with controlled initial transmit power ramp up in cdma
Inventor: LOMP GARY R
IPC: H04B1/707
Filed: 2005-02-28
Abstract: The method involves transmitting a periodic signal from a subscriber unit at an initial predetermined power level. The power level is increased at a predetermined ramp up rate. The periodic signal is detected at a base station when a sufficient power for detection is achieved. A signal from the base station is transmitted which confirms the periodic signal has been detected. The confirmation signal is received at the subscriber unit. The predetermined power level ramp up rate is stopped when the confirmation signal is received. The initial predetermined power level is lower than the power level required for detection by the base station. The power level of the signal is increased at a second predetermined rate which is less than the first rate.
Patent HK-1076269-A1 (HK)
Title: Marble or stone slab polishing machine provided with a rotating head mounted on a fulcrum
Inventor: NICOLA MONTRESOR
IPC: B24B41/00
Filed: 2005-09-22
Abstract: A horizontal supporting bar (1) comprises a plurality of motorized spindles provided with respective polishing tools or grinders (3) and is mounted at its two ends on fulcrum-type supports (4). In the present case, the supports (4) are horizontal shafts disposed on ball bearings. <IMAGE>
Patent HK-1079703-A1 (HK)
Title: Method for cardioprotection and neuroprotection by intravenous administration of halogenated volatile anesthetics
Inventor: TRILLO RAUL
IPC: A61K/
Filed: 2005-12-29
Abstract: Provided is a method of treating a patient having a tissue that is subject to an ischemic event. The method is conducted by parenterally administering a formulation containing a halogenated volatile anesthetic in an amount effective to improve the tissue's resistance to or tolerance of the ischemic event. In preferred embodiment of the invention, the amount of the formulation administered to the patient is sub-anesthetic. The formulation can be administered prior to, concurrently with, or after the ischemic event. The method can be used, for example, for treatment of patients having myocardial or neuronal tissue that is subject to an ischemic event.
Patent HK-1085721-A1 (HK)
Title: Chiral arylketones in the treatment of neutrophil-dependent inflammatory diseases
Inventor: MARCELLO ALLEGRETTI
IPC: C07C45/67
Filed: 2006-07-14
Abstract: The compounds of formula (I): where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, such as psoriasis, rheumatoid arthritis, ulcerative cholitis and for the treatment of damages caused by ischemia and reperfusion.
Patent HK-1097034-A1 (HK)
Title: Lighting appliance with a reduced encumbrance for industrial environments
Inventor: BEGHELLI GIAN PIETRO
IPC: F21S/
Filed: 2007-02-15
Abstract: A lighting appliance with a reduced encumbrance for industrial environments, comprising a head (11), equipped with an upper support (10) for hooking the appliance to the ceiling of an industrial warehouse or building in general, and two reflectors which can be disassembled from the appliance structure, one (13) above or inside the head (11), with a complex faceted optical system, and one (12) lower or outside the head (11), with a segmented geometry; a vertical regulation system of the lamp (15) of the lighting appliance allows the illuminating engineering characteristics of the appliance to be varied, obtaining different photometric conditions according to the distance of the lamp (15) from the work surface.
Patent HK-1102626-A1 (HK)
Title: Compositions and methods for the treatment and prevention of hyperproliferative diseases
Inventor: SABBADINI ROGER A
IPC: A61K/
Filed: 2007-10-09
Abstract: Monotherapies and combination therapies for treating hyperproliferative disorders are described, as are compositions for performing such methods.
Patent HK-1118744-A1 (HK)
Title: Lipoxin analogs as novel inhibitors of restenosis
Inventor: SERHAN CHARLES N
IPC: A61K/
Filed: 2008-11-18
Abstract: The present invention is directed to methods for the prevention or inhibition of restenosis. The method is accomplished by the administration of an effective amount of 15-epi-16-(para-fluoro)-phenoxy-lipoxin A, LXA, 15- epi-LXA, or 15-R/S-methyl, LXA, and pharmaceutically acceptable salts, esters, amides, carboxylic acid, or prodrugs thereof, to a subject in need thereof. As a consequence of the action of the therapeutic agent, restenosis is prevented or inhibited in the subject.
Patent HK-1123606-A1 (HK)
Title: Detector for the measurement of ionizing radiation
Inventor: PAUSCH GUNTRAM
IPC: G01T/
Filed: 2009-02-16
Abstract: The invention relates to a detector for the measurement of ionizing radiation, preferably γ-radiation and x-rays, comprising a scintillator and a light detector, the light detector being stabilized by using a predefined light source, preferably a Light Emitting Diode (LED), where the length and/or shape of the light pulses of the light source is different from the length and/or shape of the light pulses emitted by the scintillator. The light source induced pulses and the radiation induced pulses are separated from all other pulses on the basis of their pulse width. The detector is additionally stabilized by correcting the measured light output, that is the pulse height of the output signals, of the detector with the detector temperature shift, being dependant from the average pulse width of the accumulated γ-pulses.
Patent HK-1128329-A1 (HK)
Title: Method of detecting autoantibodies from patients suffering from rheumatoid arthritis, a peptide and an assaykit
Inventor: VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN
IPC: C07K7/06
Filed: 2009-07-03
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.