baber/WOPTO huggingface dataset:
Patent CR-20160335-A (CR)
Title: Dispositivo para tratamiento de superficies o realización de trabajos de mantenimiento y/o tareas de inspección del estabilizador vertical de una aeronave en un hangar de baja altura interior
Inventor: ROSTER THOMAS;
IPC: B66F11/04
Filed: 2015-01-27
Abstract: Un dispositivo para el tratamiento de superficies o para la realización de tareas de mantenimiento / inspección de la parte superior del estabilizador vertical (31) de una aeronave por al menos un técnico, que comprende: - Un único puente grúa (4)conectado a un techo (100) de un edificio de hangar; - Una única unidad de teleplataforma lateral verticalmente móvil (30) que comprende un mástil telescópico (2) conectado al puente grúa único (4), - Una estructura de andamio suspendida (20) firmemente conectada al puente grúa (4) por una estructura de soporte (5), la estructura de andamio suspendida (20) abarcando al menos una plataforma de trabajo (61,62) para realizar tareas de mantenimiento/inspección del estabilizador vertical (31) de una aeronave a diferentes alturas por al menos un técnico.
Patent CR-20210224-A (CR)
Title: Amino acid compounds and methods of use
Inventor: HOM TIMOTHY
IPC: C07D471/04
Filed: 2019-10-08
Abstract: The invention relates to compounds of formula (I), or a salt thereof, wherein R<sup>1</sup>, G, L<sup>1</sup>L<sup>2</sup>, L<sup>3</sup>, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, ανβ1 integrin and ανβ6 integrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IFF) and nonspecific interstitial pneumonia (NSTP).
Patent CR-20220394-A (CR)
Title: Fluid path connectors for medical fluid delivery
Inventor: SPOHN MICHAEL
IPC: A61M39/10
Filed: 2021-02-18
Abstract: A fluid path connector for a medical fluid delivery system, the fluid path connector including a first connector element comprising a body, a first lumen, a first flexible leg, and a second flexible leg, and a second connector element comprising a body defining an undercut, a second lumen, a channel defined in the body, and at least one sealing element positioned within the channel, in which the first flexible leg comprises a first flange and the second flexible leg comprises a second flange, and in which, upon engagement of the first connector element with the second connector element, the first flange and the second flange engage with the undercut of the body of the second connector element to prevent disengagement of the first connector element and the second connector element.
Patent CR-20220429-A (CR)
Title: Formulation of lisinopril and amlodipine
Inventor: ANEVSKA-STOJANOVSKA NATASA
IPC: A61K9/20
Filed: 2021-03-01
Abstract: The present invention relates to a novel formulation of an ACE inhibitor (such as lisinopril) and a calcium channel blocker (such as amlodipine). The formulation shows unexpected stability and an advantageous dissolution profile.
Patent CR-20230364-A (CR)
Title: Multimeric chelator compounds for use in targeted radiotherapy
Inventor: RAFIQUE WAQAS
IPC: A61K51/10
Filed: 2022-01-31
Abstract: The present invention covers compounds of general formula (I): [(C)n-L]-(V)m (I) where C is a chelator and n > 1, L is a multi-functional linker moiety comprising multiple functional groups for the covalent attachment of chelator such as a polyamine or polyacid-containing backbone or amino acid containing polymer comprising side-chains with amino, thiol or carboxylic acid moieties such as lysine, cysteine or glutamic acid and V is a tissue targeting moiety where m= 1-5 which preferentially coupled through a coupling moiety to either the multifunctional linker moiety L or directly to the chelator moiety C, and stereoisomers, tautomers, N-oxides, hydrates, solvates, and salts thereof, and mixtures of same.
Patent EC-SP045503-A (EC)
Title: Derivados de 1-[(indol-3-il)carbonil]piperazina
Inventor: COWLEY PHILLIP MARTIN
IPC: A61P25/04
Filed: 2004-12-21
Abstract: LA PRESENTE INVENCIÓN SE REFIERE A UN DERIVADO DE 1-[(INDOL-3-IL)CARBONIL]PIPERAZINA, DE ACUERDO CON LA FÓRMULA GENERAL (I), EN DONDE R REPRESENTA A SUSTITUYENTES 1-4 INDEPENDIENTEMENTE SELECCIONADOS DE H, (C1-4)ALQUILO (SUSTITUIDO OPCIONALMENTE CON HALÓGENO), (C1-4)ALQUILOXI (SUSTITUIDO OPCIONALMENTE CON HALÓGENO), HALÓGENO, OH, NH2, CN Y NO2; R1 ES (C5-8)CICLOALQUILO O (C5-8)CICLOALQUENILO; R2 ES H, METILO O ETILO; R3, R3', R4' R4', R5, R5' Y R6' SON INDEPENDIENTEMENTE HIDRÓGENO O (C1-4)ALQUILO, SUSTITUIDO OPCIONALMENTE CON (C1-4)ALQUILOXI, HALÓGENO U OH; R6 ES HIDRÓGENO O (C1-4)ALQUILO, SUSTITUIDO OPCIONALMENTE CON (C1-4)ALQUILOXI, HALÓGENO U OH; O R6 FORMA JUNTO CON R7 UN ANILLO HETEROCÍCLICO SATURADO DE 4-7 MIEMBROS, QUE CONTIENE OPCIONALMENTE OTRO HETEROÁTOMO SELECCIONADO DE O Y S; R7 FORMA JUNTO CON R6 UN ANILLO HETEROCÍCLICO SATURADO DE 4-7 MIEMBROS, QUE CONTIENE OPCIONALMENTE OTRO HETEROÁTOMO SELECCIONADO DE O Y S; O R7 ES H, (C1-4)ALQUILO O (C3-5)CICLOALQUILO, SIENDO LOS GRUPOS ALQUILO SUSTITUIDOS OPCIONALMENTE CON OH, HALÓGENO O (C1-4)ALQUILOXI; O UNA SAL FARMACÉUTICAMENTE ACEPTABLE DEL MISMO. LA INVENCIÓN TAMBIÉN SE REFIERE A COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN DICHOS DERIVADOS DE 1-[(INDOL-3-IL)CARBONIL]PIPERAZINA Y AL USO DE ESTOS DERIVADOS EN EL TRATAMIENTO DEL DOLOR, TALES COMO DOLOR PERI-OPERATORIO, DOLOR CRÓNICO, DOLOR NEUROPÁTICO, DOLOR CANCEROSO Y DOLOR Y ESPASTICIDAD ASOCIADOS CON LA ESCLEROSIS MÚLTIPLE.
Patent EC-SP077131-A (EC)
Title: Regímenes y los juegos de anticonceptivos del antagonista del receptor de progesterona
Inventor: FENSOME ANDREW
IPC: A61K31/404
Filed: 2007-01-05
Abstract: Un método de anticoncepción es provisto, el cual, implica el reparto de 21 a 27 días consecutivos de uno ó más antagonistas del PR en la ausencia de una progestina, estrógeno u otro compuesto esteroidal, seguido por 1 a 7 días sin ningún agente activo. También descrito es un juego farmacéutico útil para facilitar el reparto de este régimen.
Patent EC-SP099822-A (EC)
Title: Derivados de guanina policiclicos y sus métodos de uso
Inventor: CZARNIECKI MICHAEL F
IPC: A61K31/519
Filed: 2009-12-21
Abstract: La presente invención se refiere a Derivados de Guanina Policíclicos, composiciones que comprenden los Derivados de Guanina Policíclicos y los métodos de uso de los Derivados de Guanina Policíclicos para tratar el dolor o una enfermedad inflamatoria.
Patent EC-SP951436-A (EC)
Title: Dispositivo de valvula
Inventor: SILVERSIDES JOHN
Filed: 1995-05-05
Abstract: Un dispositivo de válvula para conectar un recipiente lleno con un material fluído, a un dispositivo aplicador, para distribuir dicho material fluído, que comprende un alojamiento unitario esencialmente en forma de copa, que tiene un pasaje para el fluído extendido axialmente en su base, y un asiento de válvula formado en torno al extremo interior del pasaje de fluído y radialmente por dentro de la pared extendida axialmente del alojamiento, un miembro de válvula unitario y esencialmente cilíndrico que es recibido en el extremo abierto de dicho alojamiento en forma de copa, que tiene un pasaje de fluído extendido axialmente en el en alineación axial con el pasaje del flujo en el alojamiento en forma de copa, y un disco de válvula situado sobre el extremo interior de dicho pasaje de flujo, pero separado de el; medios para desplazar axialmente el miembro de válvula con relación al alojamiento al producirse un movimiento giratorio de dicho alojamiento, de modo que se efectúa el acoplamiento del disco de válvula al asiento de válvula para cerrar el pasaje del fluído en el alojamiento, y el desacoplamiento para abrir el pasaje del flujo en dicho alojamiento, y medios para conectar el alojamiento al orificio de descarga del recipiente, y para conectar el miembro de válvula al orificio de recepción del aplicador.
Patent EC-SP982664-A (EC)
Title: Nuevos derivados de 2- (3h) oxazolona
Inventor: PUIG DURAN CARLES
IPC: A61K9/00
Filed: 1998-09-10
Abstract: Un compuesto de 2-(3H)-oxazolona de fórmula I: (gráfico), en donde R1 es un alquilo o un grupo amino; R2 es un naftilo, un grupo fenilo o fenilo no sustituido desde 1 a 3 átomos de halógenos ó alquilo, alcoxi o grupos trifluorometio, y R3 es hidrógeno o un grupo alquilo.
Patent EC-SP992861-A (EC)
Title: Particulas de forma estable de compuestos organicos cristalinos
Inventor: URIBE JUAN ANGELES
IPC: C07B63/02
Filed: 1999-02-18
Abstract: La presente invención provee un almacenamiento estable, a paticulas formadas de compuestos orgánicos alotrópicos. La particulas de la presente invención pueden ser formadas de acuerdo con las aplicaciones deseadas. Las formas preferidas de tales partículas son las microesferas, particularmente aquellas que tienen un diámetro de alrededor de 1 a alrededor de 1,000 micrones. Las particulas formadas estables de la presente invención, son especialmente adecuadas para la fabricación de formulaciones farmacéuticas, en las cuales, la liberación prolongada y una biodisponibilidad uniforme son deseadas. Las particulas de almacenamiento estable son formadas, por cristalización al estado sólido de los compuestos orgánicos alotrópicos. El proceso de cristalización al estado sólido de la presente invención, proporciona un medio para lograr una forma cristalina, para almacenamiento estable de dicho compuesto alotrópico, sin pérdida o deterioro de las dimensiones originales de la partícula.
Patent EC-SP993191-A (EC)
Title: Compuestos derivados de un nucleo de amina que son inhibidores de la enzima de impdh
Inventor: IWANOWICZ EDWIN J
IPC: C07K14/17
Filed: 1999-10-25
Abstract: La presente invención describe la identificación de nuevos inhibidores de IMPDH (inosina-5¿-monofosfato deshidorgenasa). Los compuestos y composiciones farmacéuticas descritos aquí son útiles para tratar o prevenir padecimientos asociados con IMPDH, tal como rechazo de transplante y enfermedades y enfermedades autoinmunes.
Patent EE-9900275-A (EE)
Inventor: KALLED SUSAN L
IPC: C07K16/28
Filed: 1998-01-09
Abstract: This invention relates to regimens for therapeutically administering anti-CD40L compounds to patients. Immune-related disorders can be effectively treated by administering anti-CD40L compounds at intervals of three weeks or more.
Patent FR-1602306-A (FR)
Title: Electro-chemically deburring cast, mach-
IPC: B24B31/00
Filed: 1968-10-14
Granted: 1970-11-09
Abstract: An electrolyte is placed near one surface of the workpiece. At least one conductive body is moved in the electrolyte near the surface. Electric current is passed through the electrolyte between two electrodes so that the body becomes a random moving auxiliary electrode which electrolytically erodes material from the surface.
Patent GB-1046072-A (GB)
IPC: A01K59/00
Abstract: 1,046,072. Filters for liquids. T.C. DRAPER. Jan.21,1964, No.2523/64. Heading B1D. In portable apparatus intended for straining wax from honey, a cylindrical supporting sieve with an out-turned flange at the top, a strainer clock, and a cylindrical coarser sieve, also with an out-turned flange at the top, are arranged with the sieve flanges resting on the edge of a vessel, the edge of the strainer cloth being located between the flanges. A valve for discharge of the strained honey is provided at the base of the vessel.
Patent GB-1051665-A (GB)
IPC: C25D11/02
Abstract: 1,051,665. Electrolytically depositing alumina coatings. YAWATA IRON & STEEL CO. Ltd. June 10, 1963 [June 15, 1962], No. 23026/63. Heading C7B. A protective coloured coating is deposited on a degreased metal surface by anodically treating it in an aqueous solution of pH 10À5 to 13 containing 5 to 50 g/1 of aluminate at a temperature between 40 and 60‹C for 1 to 4 secs. with a current density of 2 to 6 amps/dm<SP>2</SP> so as to deposit an alumina compound film of 2À5 to 6 mg./dm<SP>2</SP>. A lake-producing agent such as a aurine tricarboxylic acid salt e.g. the ammonium salt may be included in the bath in excess of 1 g/1 to deposit an aluminium lake on the metal surface, and to prevent precipitation in the bath of aluminium hydroxide a chelating agent such as tartaric acid or EDTA may also be included, as well as a surfactant. The pH of the bath may be adjusted with a caustic alkali, an alkali metal carbonate or hydrochloric, sulphuric, tartaric or oxalic acids. Typically the metal treated may be a steel sheet and, if rusted, pickling is effected also before electrolytic treatment. The electrolytic coating may be subjected to an acid or chromate dip to improve further its corrosion resistance and a paint film, e.g. a melamine or urea resin, may be applied and baked on.
Patent GB-1054157-A (GB)
IPC: G10K5/00
Abstract: 1,054,157. Liquid level indicators. SCULLY SIGNAL CO. Oct. 22, 1965 [Sept. 27, 1965], No. 44907/65. Heading G1H. A whistle signal device 30 fitted into the tank end of a vent pipe 26 is provided with a resilient flange 31 to engage the end of the pipe 26 and a bowed spring 36 to engage the inside of the pipe 26 to hold the device in position. The device is also provided with pivotally mounted doors 40 biased to the closed position by a spring 46 arranged above a strainer 35 positioned above a tube 56 and a whistle device 48, 50. The whistle is operated by escaping air driving the filling of the tank and stops when the liquid reaches the end of the tube 56. Should the liquid supply not stop when the bottom of tube 56 is reached the doors 40 yield to allow liquid to flow through the pipe 26.
Patent GB-1054291-A (GB)
IPC: C07D487/04
Abstract: 1,054,291. 1,2-Malonyl-1,2-dihydrocinnoline derivatives. SIEGFRIED A.G. Feb. 25, 1964 [Feb. 26, 1963], No. 7876/64. Heading C2C. Novel 1,2-malonyl-1,2-dihydrocinnoline derivatives of Formula I wherein R is a lower alkyl, or phenethyl group, or a phenyl group which may be substituted by a halogen atom, or a hydroxy lower alkyl or lower alkoxy group, R<SP>1</SP> is a hydrogen atom, an alkyl group having 2-6 carbon atoms which may be substituted by a halogen atom or hydroxy or lower alkoxy group, or an acyl, cyclopentyl or phenyl group, R<SP>2</SP> is hydrogen or a lower alkyl group, and R<SP>3</SP> represents one or more optional substituents selected from halogen atoms and lower alkyl groups, and wherein the terms " lower alkyl " and " lower alkoxy " groups means alkyl or alkoxy groups having 1-3 carbon atoms, and the non-toxic, pharmaceutically acceptable salts thereof, are prepared by reacting a 1,2-dihydrocinnoline compound with a malonic acid derivative of formula in which X represents a halogen atom or an alkoxy group, and, if desired, reacting a resulting product in which R<SP>1</SP> is hydrogen, or a metallic salt thereof, with a compound R<SP>1</SP>-Z in which R<SP>1</SP> has the meanings given above other than hydrogen and Z is chlorine, bromine, iodine, -SO 4 R<SP>1</SP> or an anylsulphonate, or, if desired, reacting a resulting product in which R<SP>1</SP> is hydrogen with a compound R<SP>5</SP> = 0 where R<SP>5</SP> represents R<SP>1</SP> less a hydrogen atom in the α-position, followed by hydrogenation of the unsaturated compound formed. Pharmaceutical compositions having antiinflammatory and analgesic and/or anti-pyretic activity which may be administered e.g. orally or parenterally contain as active ingredient a compound of Formula I above or a non-toxic, pharmaceutically acceptable salt thereof.
Patent GB-1054618-A (GB)
IPC: B26D11/00
Abstract: 1,054,618. Cutting-apparatus. LEIPZIGER BUCHBINDEREIMASCHINENWERKE. Nov. 15, 1965, No. 48305/65. Heading B4B. Brochures 6, 7 are trimmed and cut in three stations in the first of which a cut is made by a knife 1, in the second of which cuts are made by knives 2 and 3 and in the third of which a cut is made by a knife 4. The knife 3 or the counterknife therefor is fastened to a knife holder through the interposition of an adjustable shim.
Patent GB-1225715-A (GB)
IPC: F16K11/078
Filed: 1969-04-28
Abstract: 1,225,715. Valves. PRICE-PFISTER BRASS MFG. CO. 28 April, 1969 [1 May, 1968], No. 21551/69. Heading F2V. A mixing valve comprises a body 18 having inlets 28, 30 and an outlet 32, a seat member 34 having ports 36, 38, and 40 registering respectively with the inlets and outlet, and a valve plate 56, movable radially and rotatably about an axis X by a projection 62 on an operating arm, the valve plate 56 having an elongated cavity 58 registerable with the outlet port 40 with ends 63, 65 registerable with the inlets 36, 38, the ends being formed with sloping portions 70, 72 to reduce the curvature of the flow path through the valve. The port 40 is also formed with sloping walls 66, 68. A septum 74 directs flow to the outlet under unbalanced flow conditions. The ports 36, 38 have straight edges 36b, 38b, respectively, to provide a rapid shutoff.
Patent GB-1226671-A (GB)
IPC: H02P29/00
Filed: 1968-06-18
Abstract: 1,226,671. Control of D.C. motors. MATSUSHITA ELECTRIC INDUSTRIAL CO. Ltd. 18 June, 1968 [29 June, 1967], No. 29041/68. Heading H2J. In a phase control system for a D.C. motor a device 6 coupled to the motor 1 generates a phase dependant signal which is compared with a synchronizing signal in a phase comparator 9 the output of which is used to speed up or slow down the motor to correct its phase, the stability of the system being improved by a negative feedback loop incorporating a low pass filter 8 and a delay circuit 7 in one supply to the comparator. As shown a synchronizing signal at terminal 5 is applied to a variable delay circuit 7 whose delay depends upon the output of the filter 8. Alternatively the phase dependant signal may be delayed. The armature of motor 1, which has a permanent magnet field, is connected as one arm of a bridge circuit 1, 2, 3, 4. The output of the bridge circuit (at terminals c, d) which is proportional to the back e.m.f. and therefore the speed of the motor is applied to the base-emitter circuit of a silicon transistor 11 which controls the supply voltage to the bridge and therefore stabilizes the speed of the motor. The output of the bridge circuit is shunted by a transistor 14 and resistor 16, the transistor being controlled by the output voltage of the phase comparator 9 to alter the controlled speed of the motor with the result that motor 1 maintains both speed and phase synchronism with the signal applied to terminal 5. In alternative embodiments (Figs. 8, 9, not shown) the speed of the motor is controlled by a system employing an A.C. or D.C. tachogenerator the output of which is compared with a reference voltage. The output of the tachogenerator is shunted by a transistor responsive to the output of the comparator to vary the controlled speed. The delay circuit 52 may be a monostable circuit, the low pass filter 53 a simple T-network (Fig. 6, not shown).
Patent GB-1226963-A (GB)
IPC: G01S7/20
Filed: 1967-07-25
Abstract: 1,226,963. Wave-energy position finding &c. MARCONI CO. Ltd. 11 April, 1968 [25 July, 1967], No. 34081/67. Heading H4D. In a radar P.P.I. display system a voltage representative of the rotation of the radar aerial is fed to a resolver 6, Fig. 1, which produces sine cosine (X and Y) components of that voltage. The X component is fed to the X windings of a deflection coil system 5 of a cathode-ray tube (C.R.T.) 4 through a drive unit 7. The Y component is fed to a gain control lead 10 of an amplifier 9, and also to a first input of an adder unit 8. Video signals, representative of received echo signals, are fed from a terminal 1 through an amplifier 2 to the brightness control of the C.R.T. 4 (via a further amplifier 3), and also to a second input of the adder unit 8(via the amplifier 9). Output from the adder unit 8 is fed to the Y windings of the deflection coil system 5 through a drive unit 11 having adjustable gain, so that either a circular or an elliptical field may be obtained. A voltage which is dependent upon a video signal is thus superimposed upon one of the resolved voltage components for deflecting the C.R.T. beam. The magnitude of this superimposed voltage is made dependent upon the varying magnitude of the said component by means of the gain-controlled amplifier 9. The rotor of the resolver 6 may be turned by a handle 12, to produce a corresponding rotation of the display. In another embodiment, the brightness control of the C.R.T. is fed from the output of the amplifier (9), Fig. 2 (not shown), instead of from its input.
Patent GB-1232388-A (GB)
IPC: H02P9/26
Filed: 1968-07-19
Abstract: 1,232,388. Automatic voltage control. NEWAGE LYON Ltd. July 19, 1968, No.34607/68. Heading G3R. The subject matter of this Specification is identical with that of Specification 1, 232, 386, but the claims relate to the provision of a frequencyresponsive inductor in the sensing circuit of the control arrangement.
Patent GB-1232849-A (GB)
IPC: F16K17/06
Filed: 1968-07-22
Abstract: 1,232,849. Valves. DIENES WERKE FUR MASCHINENTEILE G.m.b.H. 22 July, 1968 [21 July, 1967], No. 34789/68. Heading F2V. In a compressor unloader of the kind in which ball 7 is urged against a seat in a stepped inlet 13 by the head 6 of a spring plunger 4 and, when the inlet pressure overcomes the plunger, is supported against a construction 10, the head 6 is of larger diameter than the constriction 10 so that the plunger mechanism remains assembled when members 1 and 2 are disconnected for maintenance purposes.
Patent GB-1234123-A (GB)
IPC: D21F9/04
Filed: 1969-01-27
Abstract: 1,234,123. Papermaking. CEMENTIFERA ITALIANA FIBRONIT S.p.A. 27 Jan., 1969, No. 4499/69. Heading D2A. A paper machine has a permeable support 13 on which the slurry is deposited, wrapped about a roller 6, wherein the roller surface comprises a cylindrical grid rotatable about its own axis, and having a length corresponding to the width of the web to be formed, said grid consisting of longitudinal members spaced apart so as to define uniform passageways extending along the whole length of the grid, there being provided a reservoir for collecting white water, adapted to be kept under reduced pressure, and having an opening making a substantially suction-tight seal with the permeable support on the opposite side to that supporting slurry, over the area of the support in contact with the grid. The grid may consist of longitudinal bars spaced, one from another, and carried by spreader rings secured to a closed drum, the bars preferably being fixed to the outer edges of the spreader rings sloping forward relatively to the direction of motion as shown by bars 11. The bars may also be longitudinal ribs carried by the surface of a cylinder, holes being formed at the bottom of intervening grooves (Fig. 7, not shown). The reservoir may consist of two side-walls connected by an upper plate 30 lying in a plane tangent to the roller, a bottom wall and a manifold arranged underneath, connected to a source of vacuum. The upper plate 30 may be foraminous, and may also comprise a section with its own, stronger suction (Fig. 4, not shown). The reservoir may have transverse sealing members in the form of diaphragms fixed to the side walls, and inserted into lateral grooves in the roller, these grooves housing ring gaskets to give a sliding seal. The grooves may be formed between end discs of the grid, and annular extensions fixed to the central portion. Rubber-covered roll 31 acts as cross-roller seal, together with flexible doctor 36. Roller 37, forming the bottom edge of feed box 43 may nip the permeable support 13. These two rolls may be replaced by flexible doctors (Fig. 7, not shown). The sealing diaphragms may also fit into grooves of the sealing roller 31 to give a transverse seal.