baber/WOPTO huggingface dataset:
Patent CA-2706837-A1 (CA)
Inventor: HUBSCHWERLEN CHRISTIAN
IPC: C07D471/04
Filed: 2008-12-17
Abstract: The invention relates to antibacterial compounds of formula (I) wherein one or two of U, V, W, and X represent N, the rest represent CH or, in the case of X, may also represent CR a wherein R  a is fluorine; R1 represents alkoxy, halogen or cyano;   R2 represents H, CH2OH, CH2N3, CH2NH2, alkylcarbonylaminomethyl or triazol- 1-ylmethyl; R3 represents H, or, when n is 1, R3 may also represent OH, NH2, NHCOR6 or triazol-1-yl; A represents CR4; K  represents O, NH, OCH2, NHCO, NHCH2, CH2NH, CH2CH2, CH=CH, CHOHCHOH or CHR5; R4 represents H or together with R5 forms a bond, or also R4 can represent OH when K  is not O, NH, OCH2 or NHCO; R5 represents OH or together with R4 forms a bond;  R6 represents alkyl; m is O or 1 and n is O or 1;  and G is as defined in the description; and to salts of such compounds.
Patent CA-2708934-A1 (CA)
Title: Artificial ventilation system and methods of controlling carbon dioxide rebreathing
Inventor: FUKUNAGA ATSUO F
IPC: B01D29/50
Filed: 1997-10-30
Abstract: A method for providing assisted ventilation which avoids hypoxia and hypocapnia is disclosed, in which a predetermined dead space in an assisted ventilation system is provided external to the patient. The method may also be used to create normocapnia or moderate hypercapnia without causing hypoxia during assisted ventilation. The improved device has an improved proximal terminal (60) and a new coaxial filter device (140).
Patent CA-2710258-A1 (CA)
Inventor: MILLER CHRISTOPHER R
IPC: B23D21/08
Filed: 2010-07-20
Abstract: A lightweight, portable, and relatively small cutting tool is described. The tool engages with a standard press tool and is used for cutting brittle pipe such as cast iron soil pipe. The tool features a cuffing chain assembly that is tensioned about the pipe by a movable ram block. The ram block is displaced by a ram or hydraulic cylinder in the press tool.
Patent CA-2710714-A1 (CA)
Inventor: RUSSELL WILLIAM SCOTT
IPC: B65D5/42
Filed: 2010-07-21
Abstract: A corrugated fiberboard container and a method and apparatus for constructing corrugated fiberboard in which different liner materials are utilized for forming the container body and flaps. A corrugated fiberboard is disclosed for use in providing a container. The fiberboard includes: a first region that forms a container body; and a second region that forms a plurality of flaps; wherein the first region and the second region are formed from a fluted medium having a liner adhered to a side of the fluted medium, wherein the liner includes: a first layer that substantially covers both the first region and the second region; and a second layer adhered to the first layer, wherein the second layer covers the first region and is omitted from covering at least a substantial portion of the second region.
Patent CA-2711624-A1 (CA)
Inventor: PARMETER LARRY J
IPC: E21B43/013
Filed: 2009-01-09
Abstract: A submersible pumping system for use downhole, wherein the system includes a pump and a pump motor for driving the pump. The pump motor includes a housing with corresponding stator and rotor lamination stacks disposed within the housing.  Also included with the pump motor is an anchoring system for axially securing the stator lamination stack within the motor housing.
Patent CA-2711919-A1 (CA)
Inventor: EVISON JANE
IPC: A61Q9/04
Filed: 2008-12-24
Abstract: A depilatory composition which is an emulsion of hydrophobic particles in a continuous aqueous phase wherein the aqueous phase-includes at least one depilatory agent and the hydrophobic particles includes a vinyl polymer derivative and a polysaccharide.
Patent CA-2712276-A1 (CA)
Title: Traitement de maladies neurodegeneratives a l'aide de progranuline (pgrn)
Inventor: KAY DENIS G
IPC: A61P25/16
Filed: 2009-01-16
Abstract: L'invention porte sur des procédés et des compositions pour traiter une maladie neurodégénérative. Plus particulièrement, la présente invention porte sur des procédés de traitement de maladies neurodégénératives à l'aide de la progranuline et de polypeptides de progranuline, et sur des procédés de traitement de maladies neurodégénératives à l'aide d'effecteurs, ou de combinaisons d'effecteurs, qui modifient l'expression de la progranuline.
Patent CA-2713357-A1 (CA)
Inventor: DAVIS BENJAMIN L
IPC: C01B35/14
Filed: 2009-01-14
Abstract: Method of producing ammonia borane, comprising providing polyborazylene;  digesting the polyborazylene with a dithiol-containing agent to produce a boro-sulfide compound and a byproduct; converting the byproduct to the boro-sulfide product of step (b) by reaction with a first alkyl-tin hydride; and, converting the boro-sulfide compound produced in steps (b) and (c) to ammonia borane by reaction with a second alkyl-tin hydride.
Patent CA-2714553-A1 (CA)
Title: Rinse aid compositions with improved characteristics
Inventor: NAGY ANDRAS
IPC: C11D3/18
Filed: 2009-02-05
Abstract: The present invention is directed to rinse aid compositions with improved biodegradability that may be used in automated carwash operations to promote drying and improve the appearance of vehicles. The rinse aid compostion comprises : a) an emulsifier comprising of: i) at least one compound of formula (A), and ii) at least one compound of formula (B) wherein for both compounds of formula (A) and (B): R1 and R4 are each independently a C7-C21 alkyl or alkenyl; R2 and R3 are each independently a C1-C6 alkyl; X is an organic or inorganic anion; and b) a hydrophobe.
Patent CA-2715732-A1 (CA)
Inventor: EPSTEIN GORDON
IPC: A61N1/00
Filed: 2008-11-14
Abstract: An ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an intemallumen within the cannula and a cannula axis. A plurality of conductors contained within the lumen, each conductor has a proximal end and a distal end. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled at the respective proximal end of the stylet to the distal end of a respective conductor, the stylets comprise a deflectable material, and are mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, configured and positioned to deflect, in response to axial movement of the stylets in a direction from the proximate end of the cannula to the distal end of the cannula.
Patent CA-2719948-A1 (CA)
Inventor: LAMBERT DAVID
IPC: A23L3/06
Filed: 2008-03-31
Abstract: An apparatus for the heat treatment of a product, especially a food product such as a food product contained within a hermetically sealed container (11) or pouch of plastics or like material, for example for sterilisation, pasteurisation or cooking, which apparatus comprises: a heating unit (2) to bring product from ambient towards a heat treatment temperature and pressure; a retort unit (3) to apply a heat treatment to a product; and a cooling unit (5) to allow product to be brought down from heat treatment temperature and pressure towards ambient; wherein each unit (45) and retort (3) is selectably sealable from the others and from ambient conditions; and wherein the retort (3) comprises a retort chamber enclosing a volume incorporating a plurality of mounting means (30) orbitally mounted about a longitudinal axis of the chamber so that each mounting means (30) is movable at least between a first position whereat it is aligned with an outlet of the heating unit whereby product can be loaded into the mounting means, and a second position whereat it is aligned with an inlet to the cooling unit whereby product can be unloaded from the mounting means (30); one or more conveyors (40) to pass product through to the apparatus.
Patent CA-2720605-A1 (CA)
Inventor: GLOMSET KENNETH
IPC: B01F5/06
Filed: 2010-11-10
Abstract: The invention relates to a device for supplying gas into water, especially for aquaculture. For enhanced oxygenation we propose a water inlet arrangement with a pipe (4) having a plurality of openings (6) and a Venturi type gas dissolver unit (2) built in the pipe (4), and a surrounding second element (8) having a plurality of openings (10) and/or a fixed or adjustable shield (12).
Patent CA-2720748-A1 (CA)
Title: Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (dnl) technology
Inventor: CHANG CHIEN-HSING
IPC: C07K16/28
Filed: 2009-04-06
Abstract: The present invention concerns methods and compositions for forming cytokine-antibody complexes using dock-and-lock technology. In preferred embodiments, the cytokine-MAb DNL complex comprises an IgG antibody attached to two AD (anchor domain) moieties and four cytokines, each attached to a DDD (docking and dimerization domain) moiety. The DDD moieties form dimers that bind to the AD moieties, resulting in a 2:1 ratio of DDD to AD. The cytokine-MAb complex exhibits improved pharmacokinetics, with a significantly longer serum half-life than naked cytokine or PEGylated cytokine. The cytokine-MAb complex also exhibits significantly improved in vitro and in vivo efficacy compared to cytokine alone, antibody alone, unconjugated cytokine plus antibody or cytokine-MAb DNL complexes incorporating an irrelevant antibody. Most preferably, the complex comprises an anti-CD20 IgG antibody conjugated to four IFN-a2b moieties, although other antibodies and cytokines have been used to form DNL complexes.
Patent CA-2721239-A1 (CA)
Inventor: BERGER UWE
IPC: C10G1/10
Filed: 2009-04-24
Abstract: The invention relates to a method for the direct thermochemical conversi-on of high molecular weight organic starting products into low molecular weight organic products that are liquid with a low viscosity at ambient temperature and can be combus-ted. Said method consists of the following steps: (1) the starting product, at least one re-ducing gas and slow-evaporating product fractions are provided in a reactor, (2) the provided starting material is rapidly heated to a reaction temperature, (3) said starting mate-rial is converted using the temperature, the reducing effect of the gas and autocatalytical effects of the product fractions in vaporous reaction products and reaction gas, (4) the re-action gas is separated by means of condensation by evacuating the condensed reaction products, said separated reaction gas comprising a mixture of hydrogen, methane and other hydrocarbons and carbon monoxide and carbon dioxide. Said claimed method is characterised by other additional steps: (5) the separated reaction gas is conditioned by discharging at least one part of the gas mixture and optionally, introducing hydrogen, said conditioning followed by (6) re-injecting the conditioned reaction gas into the reac-tor for simultaneously producing a hydrating, reducing and stripping effect for converting the starting material. According to the invention, the amount of active gas fractions and its part in the total flow of the reaction gas can be modified in an advantageous manner, thus increasing the effectiveness of the method and leading to an improvement of the tar-get product quality and yield with total lower production costs. The invention also relates to a method for carrying out the claimed method.
Patent CA-2725960-A1 (CA)
Inventor: MICKELER SIEGFRIED
IPC: F03D1/06
Filed: 2010-12-20
Abstract: The invention concerns a rotor blade (6).and a wind turbine (1) with such a rotor blade (6), wherein the absolute length L of the rotor blade (6) extends from the blade attachment (11) to the blade tip (12) and the relative blade length x/L  proceeds from the blade attachment (11). The rotor blade (6) is divided into an inner longitudinal section L;  associated with the blade attachment (11) and an outer longitudinal section L  a associated with the blade tip (12), wherein the transition from the inner longitudinal section L i to the outer longitudinal section L a defines the cross-sectional plane E o, and the blade tip (12) defines the cross-sectional plane E E. As a function of the relative blade length x/L, the rotor blade (6) has a specific aerodynamic profile with a chord t, a twist .theta., a relative thickness d/t, a relative curvature f/t, and a relative trailing edge thickness h/t. In order to reduce acoustic emissions without having to accept appreciable losses in performance, it is proposed according to the invention that the cross-sectional plane E o is located at a relative blade length x/L in the range between 0.80 and 0.98, the blade chord t of the aerodynamic profile in the cross-sectional plane E E is at least 60% of the blade chord t of the aerodynamic profile in the cross-sectional plane E o, and the blade twist .theta. of the aerodynamic profile in the cross-sectional plane E E is greater than the blade twist .theta. of the aerodynamic profile in the cross-sectional plane E o.
Patent CA-2727528-A1 (CA)
Inventor: GUPTA AJAY
IPC: A61K31/4164
Filed: 2008-06-13
Abstract: Disclosed are compounds of the general formula (1): compositions comprising an effective amount of said compounds either alone or in combination with other chemotherapeutic agents, and methods useful for treating or preventing cancer and for inhibiting tumour tissue growth. These compounds attenuate the oxidative damage associated with increased heme-oxygenase activity and can reduce cell proliferation in transformed cells. In addition, the described compounds and compositions are useful as neuroprotectants and for treating or preventing neurodegenerative disorders and other diseases of the central nervous system.
Patent CA-2727791-A1 (CA)
Inventor: BOUDREAULT DAVID
IPC: A61B17/58
Filed: 2009-06-12
Abstract: A method of treating a patient's oint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A  diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.
Patent CA-2728884-A1 (CA)
Title: Active nanocomposite materials and the process for obtaining them
Inventor: LAGARON CABELLO JOSE MARIA
IPC: C08K11/00
Filed: 2009-06-25
Abstract: The present invention refers to new active nanocomposite materials, comprising a matrix and additives. The present invention also describes a process for obtaining these nanocomposite materials and their use in various industry sectors.
Patent CA-2730358-A1 (CA)
Inventor: KIM JIN PIL
IPC: H04L12/24
Filed: 2000-10-06
Abstract: A virtual channel table for broadcasting protocol and a method for broadcasting by using the virtual channel table includes identification information identifying and permitting discrimination of active and inactive channels contained in the virtual channel table. At a receiver, the virtual channel table transmitted from the transmitting side is parsed, thereby determining whether the current received channel is an active or inactive channel.
Patent CA-2731656-A1 (CA)
Inventor: TELFER GEORGE
IPC: E21B37/02
Filed: 2009-08-06
Abstract: A method of drilling and cleaning a wellbore whilst rotating the drill string after full drilling depth is reached without running the drill string out the bore to install a clean up work string is disclosed wherein a drill string having a drill bit at one end includes at least one near bit selectively activatable cleaning tool (10, 11, 12) mounted within the length of the drill string, said cleaning tool having a cleaning member (18) adapted to be moved from a close fitting stowed configuration within a recess (17) to a deployed configuration upon a body of the tool, wherein the cleaning member has magnets (19, 43) for use in positioning thereof, and compact tools for scraping, milling and brushing with improved resistance to ingress of detritus, debris and formation particulates are disclosed.
Patent CA-2732335-A1 (CA)
Inventor: VOCADLO DAVID JARO
IPC: A61K31/437
Filed: 2009-07-31
Abstract: The invention provides compounds of Formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
Patent CA-2733792-A1 (CA)
Title: Bone mineral density ratios as a predictor of osteoarthritis
Inventor: LO GRACE H
IPC: A61B5/00
Filed: 2009-08-25
Abstract: The present invention relates to systems, compositions, and methods for using bone mineral density ratios as a predictor of osteoarthritis. In particular, the present invention relates to comparing ratios of bone mineral density involving bones that are periarticular to determine a risk assessment for features of osteoarthritis.
Patent CA-2736031-A1 (CA)
Inventor: STEPNIAK FRANK
IPC: H01R4/60
Filed: 2005-06-01
Abstract: An apparatus and method of operation are disclosed for a high current electrical connector system and switch. The system includes a male pin having a first end and a second end formed by a pair of resilient slotted legs and a central axial bore in the second end. Also included is a female socket having a substantially cylindrical side wall and a bottom surface which define a cavity, an open end and a post that extends from the bottom surface. The male pin slotted legs are received in and in electrical contact with the female socket cavity. The female socket post is received in and electrical contacts with the bore in the second end of the male pin whereby the second end of the pin is trapped in the female socket between the cavity and post.
Patent CA-2737000-A1 (CA)
Inventor: QUANTE HERIBERT
IPC: F28C1/10
Filed: 2011-04-11
Abstract: The present invention relates to a floating noise reduction system for moving and/or falling fluids, the process for manufacturing of such system and the use of such system.
Patent CA-2738885-A1 (CA)
Inventor: REILLY PAUL A
IPC: A61K31/4439
Filed: 2009-11-10
Abstract: A method for preventing stroke in a patient suffering from atrial fibrillation, wherein the patient has no risk factors for major bleeding events, the method comprising administering to the patient a dosage of > 150 mg b.i.d. to 300 mg b.i.d. of dabigatran etexilate, optionally in the form of a pharmaceutically acceptable salt thereof.
Patent CA-2742549-A1 (CA)
Inventor: LEFEVRE MICHEL
IPC: B01J23/745
Filed: 2009-10-02
Abstract: A catalyst precursor comprising (A) a microporous support, (B) a non-noble metal precursor, and (C) a pore-filler, wherein the micropores of the microporous support are filled with the pore-filler and the non-noble metal precursor so that the micropore surface area of the catalyst precursor is substantially smaller than the micropore surface area of the support when the pore-filler and the non-noble metal precursor are absent is provided. Also, a catalyst comprising the above catalyst precursor, wherein the catalyst precursor has been pyrolysed so that the micropore surface area of the catalyst is substantially larger than the micropore surface area of catalyst precursor, with the proviso that the pyrolysis is performed in the presence of a gas that is a nitrogen precursor when the microporous support, the non-noble metal precursor and the pore-filler are not nitrogen precursors is also provided. Methods of producing the catalyst precursor and the catalyst are provided.
Patent CA-2742763-A1 (CA)
Inventor: FRUEHAUF JOHANNES HEINRICH
IPC: C12N1/21
Filed: 2009-11-13
Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium or BTP. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating viral diseases and disorders.  The bacterium or BTP includes one or more siRNAs or one or more DNA  molecules encoding one or more siRNAs.    Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
Patent CA-2743381-A1 (CA)
Inventor: SURJAATMADJA JIM B
IPC: E21B41/00
Filed: 2009-11-18
Abstract: A wellbore servicing apparatus, comprising a housing comprising a plurality of housing ports, a sleeve being movable with respect to the housing, the sleeve comprising a plurality of sleeve ports to selectively provide a fluid flow path between the plurality of housing ports and the plurality of sleeve ports, and a sacrificial nozzle in fluid communication with at least one of the plurality of the housing ports and the plurality of sleeve ports. A method of servicing a wellbore, comprising placing a stimulation assembly in the wellbore, the stimulation assembly comprising a housing comprising a plurality of housing ports, a selectively adjustable sleeve comprising a plurality of sleeve ports, and a sacrificial nozzle in fluid communication with one of the plurality of the housing ports and the plurality of sleeve ports, the sacrificial nozzle comprising an aperture, a fluid interface, and a housing interface.
Patent CA-2754531-A1 (CA)
Title: Antibody drug conjugates (adc) that bind to 24p4c12 proteins
Inventor: GUDAS JEAN
IPC: A61K39/00
Filed: 2010-03-05
Abstract: Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein.  24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I.  Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
Patent CA-2754997-A1 (CA)
Title: High pressure variable displacement piston pump
Inventor: HUTTO WALTER DECANIA JR
IPC: F04B1/29
Filed: 2010-02-09
Abstract: A variable flow pump includes: a housing with inlet and outlet chambers interconnected by a main bore and a non-rotating cylinder block positioned in the main bore. The cylinder block includes: a central bore communicating with the inlet chamber; cylinder bores arrayed around the central bore; first feed passages interconnecting the inlet chamber and the cylinder bores, defining a bypass flowpath between the cylinder bores; and at least one discharge valve disposed at the second end which permits fluid flow from the cylinder bores to the discharge chamber but prevents opposite flow; Pistons are disposed in the bores.  A shaft is coupled to the pistons so as to cause them to reciprocate through an axial pump stroke when the shaft is rotated. A  mechanism is coupled to the cylinder block which modulates the axial position of the cylinder block within the housing, varying the size of the bypass flowpath.
Patent CA-2756805-A1 (CA)
Inventor: SCHOPPMEIER JAN
IPC: B29C70/30
Filed: 2010-04-14
Abstract: The invention relates to an apparatus (10) for draping knitted fiber fabrics during the production of curved profiled structural parts of fiber composite material.  The apparatus (10) comprises at least one mold (10) having a mold surface (14) which corresponds to at least a portion of the desired profile geometry and curvature of the subsequent profiled structural part, furthermore at least one clamping device (20) for clamping in at least one layer (16, 18) of a knitted fiber fabric along a tensioning line (22) in a prestressed state, and finally a movement device (24) for producing a relative movement between the mold (12) and the at least one clamped-in layer (16, 18) of the knitted fiber fabric in such a way that the mold surface (14) of the mold (12) moves close to the knitted fiber fabric layer (16, 18) in a direction perpendicular or at least approximately perpendicular to the tensioning line (22) and, in the further course of the relative movement, pushes through the tensioning line (22) to such an extent that the knitted fiber fabric layer (16) completely covers the mold surface (14), wherein the clamping device (20) is equipped to load the layer (16) of the knitted fiber fabric during the entire draping operation with a tensile force acting along the tensioning line (22).