baber/WOPTO huggingface dataset:
Patent CA-3099958-A1 (CA)
Inventor: STEDMAN HANSELL
IPC: A61K48/00
Filed: 2019-04-16
Abstract: Described herein are triple-splice mutants of dystrophin or utrophin and methods of use thereof for treating Duchenne Muscular Dystrophy. Also provided are viral vectors which comprise a nucleic acid encoding a triple-splice mutant dystrophin or utrophin under the control of regulatory elements direct expression thereof.  Compositions are also provided which contain such viral vectors formulated for delivery to a human patient.
Patent CA-3101492-A1 (CA)
Title: System and method for controlling access to account transaction information
Inventor: SHAH SALIK
IPC: G06F21/62
Filed: 2020-12-03
Abstract: Attorney Docket No. 067519.0002088 ABSTRACT  In a method of controlling account user access to transaction information for a joint account, a set of control criteria is stored in a control database. Information for a new transaction is received and stored in a transaction information database. An information limitation request to prevent access to the transaction information by a second account user for a withholding time interval is received from a first account user. An access limitation record including identification of the second account user and the withholding time interval is stored in the information control database. Upon receiving from a second account user a request for account information including the transaction information, a determination may be made as to whether the transaction information should be withheld from the second account user. Responsive to a determination that the transaction information should be withheld, a response excluding the transaction information is transmitted to the second user device.   Date Recue/Date Received 2020-12-03
Patent CA-3103617-A1 (CA)
Inventor: PRYBOLSKY ROBERT PETER
IPC: G16H50/20
Filed: 2019-06-13
Abstract: L'invention concerne une méthode d'abaissement de la glycémie chez un sujet qui en a besoin par l'administration d'une composition pharmaceutique anti-hyperglycémique à base de biguanide à un sujet qualifié pour un accès sans ordonnance à la composition pharmaceutique anti-hyperglycémique à base de biguanide. Dans certains modes de réalisation, la composition pharmaceutique anti-hyperglycémique à base de biguanide comprend un diamide N,N-diméthylimidodicarbonimidique, ou un sel pharmaceutiquement acceptable de celui-ci. Dans certains modes de réalisation, la composition pharmaceutique anti-hyperglycémique à base de biguanide comprend du chlorhydrate de metformine.
Patent CA-3104358-A1 (CA)
Title: Ablation lesion device
Inventor: QIAN PIERRE
IPC: A61N5/02
Filed: 2019-07-18
Abstract: The invention relates to an ablation device for delivery of microwave energy to a selected region of tissue, in particular for producing deep endocardial or epicardial ventricular lesions, such as for the treatment or prevention of arrhythmias. The device includes a microwave radiation antenna electrically connectible via a microwave feedline to an electrical microwave system, the microwave antenna configured to generate a microwave field able to ablate tissue in said selected region of tissue, the antenna positioned within an antenna-receiving portion of an elongated catheter configured to allow fluid flow along the catheter to exit through one or more orifices in the catheter wall, the catheter provided with an electrical sensing system including one or more metal electrodes and being independent of the electrical microwave system, the device configured such that in use the electrical sensing system includes an electric circuit which incorporates an ionic conductivity bridge formed between said one or more metal electrodes and the fluid exiting said one or more orifices, the ionic conductivity bridge traversing said catheter antenna-receiving portion.
Patent CA-3107358-A1 (CA)
Title: Improved dumbbell
Inventor: RUDAN MICHAEL
IPC: A63B21/072
Filed: 2021-01-28
Abstract: ABSTRACT An improved dumbbell free weight is discussed, which includes one or more base weights, the dumbbell further having a pair of second, upper weights positioned above where the upper weights are suspended by upper braces extending from a handle attached to the one or more base weights. Date Recue/Date Received 2021-01-28
Patent CA-3109355-A1 (CA)
Inventor: PARK SOON
IPC: A61M39/20
Filed: 2019-07-16
Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.
Patent CA-3109810-A1 (CA)
Title: Implantable closed-loop neuromodulation device, systems, and methods of use
Inventor: CARMENA JOSE M
IPC: A61N1/05
Filed: 2019-08-28
Abstract: Described herein are implantable closed-loop neuromodulation devices, systems that includes such devices and an interrogator configured to emit ultrasonic waves that power the device, methods of using such devices and systems, and methods of modulating neural activity. The implantable device can include one or more curved members extending from a body. The curved members are configured to at least partially circumscribe a nerve, and include one or more electrode pads. The body includes an ultrasonic transducer configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy; and a computational circuit configured to receive a detection signal based on a detected electrophysiological signal, generate a stimulation signal based on the detection signal, and operate the electrode pads of to emit an electrical pulse to the nerve based on the stimulation signal.
Patent CA-3110921-A1 (CA)
Inventor: GRANT RUSSELL PHILLIP
IPC: G01N33/68
Filed: 2019-10-02
Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the analysis of ascorbic acid in biological samples.
Patent CA-3111578-A1 (CA)
Title: Apparatus and process for medical imaging
Inventor: ABBOSH AMIN
IPC: A61B5/05
Filed: 2019-09-04
Abstract: A process for medical imaging, the process including: (i) receiving scattering data representing mono-static or multi-static measurements of scattering of electromagnetic signals from tissues of a body part of a subject at a plurality of different signal frequencies, wherein electromagnetic signals are emitted from one or more antennas and the corresponding scattered signals are measured by the one or more antennas; (ii) processing the scattering data to calculate electric field power values at each of a plurality of scattering locations of the subject's tissues within the body part and for each of the plurality of frequencies; (iii) for each of the scattering locations, summing the calculated electric field power values at the scattering location over the plurality of frequencies and the plurality of antennas to generate an image of the tissues within the body part; and (iv) iteratively updating a model of the tissues within the body part based on a comparison of the model with the generated image until a termination criterion is satisfied, wherein the updated model is output as an image of the subject's tissues within the body part.
Patent CA-3111864-A1 (CA)
Inventor: ZHANG YANXIA
IPC: H04W28/06
Filed: 2019-09-06
Abstract: The present disclosure provides an Ethernet packet header compression method, a decompression method, and a device. Said compression method comprises: transmitting, by means of a transmitting PDCP entity of a transmitting end, a first PDCP PDU corresponding to a first data radio bearer (DRB); when the first DRB configures the Ethernet packet header compression function, the first PDCP PDU comprises: one or more pieces of first information, the first information being used for indicating whether a specific Ethernet domain in an Ethernet packet header of a first PDCP SDU corresponding to the first PDCP PDU is multiplexed.
Patent CA-3113956-A1 (CA)
Title: Galactoside inhibitor of galectins
Inventor: ZETTERBERG FREDRIK
IPC: C07H19/056
Filed: 2019-10-09
Abstract: The present invention relates to a compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore, the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.
Patent CA-3117358-A1 (CA)
Title: Systems of distribution of edible products with enhanced access dispositions and geometries
Inventor: NABEIRO RUI MIGUEL
IPC: A47J31/46
Filed: 2019-10-22
Abstract: The present invention discloses a system of distribution of edible products, comprising an apparatus (1), in particular an apparatus (1) for preparing beverages, in particular aromatic beverages such as espresso coffee and similar, which comprises a receptacle placement arrangement (2) adapted for placement of a receptacle (10, 10') for receiving an edible product, and an apparatus casing (3) and an access arrangement (4) that provides selective access to said receptacle placement arrangement (2), for example for the placement of said receptacle (10, 10'), wherein said apparatus casing (3) and said access arrangement (4) jointly form a coherent geometry, devoid of cavities or projections, at least when said access arrangement (4) is closed.
Patent CA-3119102-A1 (CA)
Title: Cannabis plants with a cannabinoid profile enriched for cannabidiol and .delta.-9-tetrahydrocannabinol
Inventor: ELKINS AARON CHRISTOPHER
IPC: A01H5/02
Filed: 2019-11-08
Abstract: The present disclosure relates generally to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total CBD (i.e., cannabidiol (CBD) and cannabidiolic acid (CBDA)) and for total THC (i.e., ?-9-tetrahydrocannabinol (THC) and ?-9-tetrahydrocannabinolic acid (THCA)).
Patent CA-3121019-A1 (CA)
Title: Method and device for detecting a rotating stall adversely affecting a turbojet engine compressor
Inventor: HERDA SOUFIANE
IPC: F04D27/00
Filed: 2019-11-29
Abstract: The method for detecting a rotating stall comprises; - a step (E90, E100) of determining a level of variation of a static pressure in a combustion chamber of the turbojet engine around an average value of this static pressure; - a step (E11) of comparing the level of variation of the static pressure relative to a first threshold (THR.1); - a step (E140) of comparing a temperature measured at the outlet of a turbine of the turbojet engine relative to a second threshold; and - if the level of variation of the static pressure is greater than the first threshold and the temperature at the outlet of the turbine is greater than the second threshold, a step (E170) of detecting the presence of a rotating stall.
Patent CA-3121950-A1 (CA)
Inventor: LIU YI
IPC: H02K3/28
Filed: 2019-12-06
Abstract: La présente invention concerne un moteur contra-rotatif et un mélangeur à grande vitesse, le moteur contra-rotatif comprenant un stator, un onduleur, un rotor interne et un rotor externe, le stator étant pourvu d'un enroulement externe et d'un enroulement interne, et l'enroulement externe et l'enroulement interne ayant des séquences de phase opposées ; l'onduleur est connecté en parallèle à l'enroulement externe et à l'enroulement interne afin de fournir de manière synchrone un courant d'excitation à ces derniers ; le rotor interne est disposé dans l'enroulement interne et est destiné à tourner dans un premier sens sous l'action de l'enroulement interne ; le rotor externe est disposé dans l'enroulement externe et est destiné à tourner dans un second sens opposé au premier sens sous l'action de l'enroulement externe. Le moteur contra-rotatif de la présente invention est pourvu de deux ensembles d'enroulements et de rotors correspondants internes et externes, et commande de manière synchrone l'enroulement externe et l'enroulement interne par l'intermédiaire d'un ensemble d'onduleurs, peut éviter l'utilisation d'une brosse, réduire le bruit et améliorer la durée de vie du moteur, et en même temps, étant donné que l'utilisation de deux ensembles d'onduleurs n'est pas nécessaire, le coût est plus faible et la commande est simplifiée.
Patent CA-3122139-A1 (CA)
Title: Circular stapler
Inventor: CHEN ZHI
IPC: A61B17/115
Filed: 2019-12-20
Abstract: A circular tubular stapler, comprising a stapler body, a handle assembly, and a staple pushing rod (75). A pointer (5) and an impact portion are further provided in the stapler body, and the pointer (5) can be rotatably connected to the stapler body; when the stapler is in an initial state, the pointer (5) is located in a first position area, and the pointer (5) presses against the impact portion; when the stapler is in a trigger state, the pointer (5) moves to a second position area, and the pointer (5) is separated from the impact portion; when the stapler is triggered completely, the pointer (5) returns from the second position area to the first position area, and collides with the impact portion to produce an impact sound. The impact portion is provided in the stapler body; when the trigger is completed, the pointer (5) returns from the second position area to the first position area, and can collide with the impact portion to produce the impact sound; an operator is prompted to successfully complete the trigger by means of the sound, the operator can timely grasp the trigger state of the stapler, and the use experience is improved.
Patent CA-3123084-A1 (CA)
Title: Dimerizing agent regulated immunoreceptor complexes
Inventor: JARJOUR JORDAN
IPC: G06F21/72
Filed: 2019-12-13
Abstract: The present disclosure provides improved compositions for adoptive T cell therapies for treating, preventing, or ameliorating at least one symptom of a cancer, infectious disease, autoimmune disease, inflammatory disease, and immunodeficiency, or condition associated therewith.
Patent CA-3123585-A1 (CA)
Title: An integrated multi-purpose hockey skatemill and its control/management in the individual training and testing of the skating and hockey skills
Inventor: CUPA PAVOL
IPC: A63B63/00
Filed: 2018-12-19
Abstract: An integrated multi-purpose hockey skatemill with a movable skatemill belt (2) comprising a stationary area of the artificial ice (1) with a front face of the work area wherein a movable skatemill belt (2) is built in by means of barrier-free transition areas with a system of spaced signalization/display elements (5) hung on the tiltable/sliding brackets (5a) at the frontal and lateral sectors with respect to the center of the movable skatemill belt (2). There is a safety restraint system (3) and a stabilization system (4) anchored above the movable skatemill belt (2). A tensile/compressive force measuring system (8) is suspended from above in the longitudinal axis of the movable skatemill belt (2). The said skatemill comprises an electronic control system (9) controlling the operation of the movable skatemill belt's (2) drive system, the system of signalization/display elements (5), the system of optical scanning cameras (6) and the tensile/compressive force measuring system (8). There are two puck feeders (7) located on the border line defining the front side of the work area. There is a hockey goal structure with target zones impact detection sensors located on the edge of the work force in front of the movable skatemill belt (2). Two laser markers (12) used to define the width of a skate track may be located on the stationary area of the artificial ice in front of the movable skatemill belt.
Patent CA-3125278-A1 (CA)
Inventor: STEGER MATTHIAS
IPC: A61K31/421
Filed: 2019-12-27
Abstract: La présente invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable correspondant : A étant un résidu 5-oxazolyle ou un résidu pyridine-4-yle, R1 étant choisi dans le groupe constitué par le fluoro et le chloro ; R2, R3, R4, R5 et R66 du cycle phényle B étant choisis indépendamment les uns des autres dans le groupe constitué par un atome d'hydrogène, un alkyle linéaire ou ramifié ayant 1 à 4 atomes de carbone, le trifluorométhyle, le 2,2,2-trifluoroéthyle, le méthylsulfanyle, l'éthylsulfanyle, le méthylsulfonyle, l'éthylsulfonyle, le difluorométhoxy, le trifluorométhoxy, le fluoro, le bromo, le chloro, le méthoxy, l'éthoxy, le propoxy, le butoxy, l'hydroxy et l'amino ; et au moins deux parmi R2, R3, R4, R5 et R6 représentant des atomes d'hydrogène, à condition que si R1 représente un chloro, R5 ne soit pas un méthoxy. Lesdits composés sont utiles en tant que substances thérapeutiquement actives dans le traitement et/ou la prévention de maladies neurorétiniennes, et en particulier dans le traitement et/ou la prévention de maladies neurorétiniennes conduisant à une perte ou à une dégénérescence des photorécepteurs de la rétine externe.
Patent CA-3126075-A1 (CA)
Title: Tamper evident container cap method and apparatus
Inventor: YU DAVID
IPC: B65D41/34
Filed: 2021-07-26
Abstract: A cap for a container includes an annular tamper evident band with a generally rigid cylindrical frame having an upper ring and a plurality of ribs extending axially from the ring and spaced circumferentially apart about the ring. A plurality of retainer elements are supported by the frame, each retainer element connected at circumferentially opposed ends by resiliently flexible webs to adjacent ones of the ribs.  The retainer elements are biased to a radially contracted position, in which the retainer elements protrude inwardly to engage an underside surface of a neck flange of the container. The retainer elements are movable to a radially expanded position in which the retainer elements can be advanced axially past the neck flange when installing the cap onto the container for the first time.
Patent CA-3127823-A1 (CA)
Title: Vehicle routing with local and general routes
Inventor: NAGY BRYAN JOHN
IPC: G01C21/34
Filed: 2020-01-24
Abstract: Various examples are directed to systems and methods for controlling an autonomous vehicle. For example, a navigator system at an autonomous vehicle may generate a plurality of local routes beginning at a vehicle location and extending to a plurality of local route end points. The navigator system may access general route cost data, the general route cost data describing general route costs from the plurality of local route end points to a trip end point. The navigator system may select the first local route of the plurality of routes based at least in part on the general route cost data. A vehicle autonomy system at the autonomous vehicle may begin to control the autonomous vehicle along the first local route.
Patent CA-3128671-A1 (CA)
Inventor: CHISHOLM BRIAN J
IPC: B29C64/112
Filed: 2020-03-04
Abstract: La présente invention concerne un ou plusieurs contenants pourvus d'une matrice séchée aux ultraviolets (UV) et des procédés de création de ces contenants. Par exemple, un contenant en verre (10) selon la présente invention comporte un fond (16) et un corps (14) s'étendant dans une direction s'éloignant du fond le long d'un axe longitudinal (LA). Le corps présente une surface (18) pourvue d'une matrice séchée aux UV (20) comprenant des gouttes de vernis séchant aux UV (30) disposées dans une pluralité de couches (50, 52), des vides (32) existant entre ces gouttes pour former une structure de matrice poreuse (24). Un procédé pour former le contenant en verre consiste à appliquer une couche de vernis séchant aux UV sur une surface extérieure du contenant en verre sous la forme d'une pluralité de gouttes de vernis de manière à créer une pluralité de vides entre les gouttes de vernis, sécher la couche de vernis séchant aux UV, appliquer une ou plusieurs couches supplémentaires de vernis séchant aux UV et sécher la ou les couches supplémentaires de vernis séchant aux UV, l'ensemble des gouttes de vernis et des vides formant la matrice séchée aux UV.
Patent CA-3130166-A1 (CA)
Inventor: CHARPENTIER SEBASTIEN MAURICE LUCIEN
IPC: F01D5/28
Filed: 2020-02-21
Abstract: Procédé de réparation d'une aube (10) d'hélice de turbomachine, en particulier de soufflante de turbomachine, cette aube comportant une pale (12) en composite à matrice organique et un bouclier métallique (14) collé sur un bord d'attaque de la pale, le bouclier métallique (14) présentant une zone endommagée (20), le procédé comprend une étape de recalage du bord d'attaque de la pale, une étape de refroidissement de l'intégralité de la pale, puis une étape de rechargement de la zone endommagée (20), par apport d'un matériau métallique sur cette zone endommagée (20) et fusion laser du matériau, et une étape d'ajustage de la zone endommagée (20) par usinage du matériau fondu.
Patent CA-3132765-A1 (CA)
Inventor: BLANDINO THOMAS PAUL
IPC: H02J7/00
Filed: 2020-03-09
Abstract: An aerosol generating device comprises an induction heating circuit for inductively heating a susceptor arrangement to heat an aerosol generating material to thereby generate an aerosol. The device is configured such that during operation a level of electromagnetic radiation emitted by the device is: less than 40dBµV/m over a frequency range of 30MHz to 225MHz and/or less than 47dBµV/mover a frequency range of 235MHz to 1GHz, and/or less than 70dBµV/mover a frequency range of 1GHz to 3GHz, and/or less than 74dBµV/mover a frequency range of 3GHz to 6GHz.
Patent CA-3133132-A1 (CA)
Inventor: ROUJEAU JEAN-CLAUDE
IPC: C12Q1/68
Filed: 2020-03-12
Abstract: Methods for assessing the risk of developing adverse drug reaction in a subject in need of such assessment are provided, comprising the step of detecting the presence of an HLA-B allele in a sample obtained from the subject, wherein the presence of allele is indicative of the subject having an increased risk of developing the adverse drug reaction. Also provided are methods of treating or reducing the incidence of the adverse drug reaction.
Patent CA-3133659-A1 (CA)
Inventor: RITTER HELMUT
IPC: A61K6/61
Filed: 2020-04-09
Abstract: Disclosed herein is a dental material containing a polymerizable hydrolysis stable polycyclic amide monomer. The present disclosure relates to methods of making and use of the polymerizable hydrolysis stable polycyclic amide monomer for the preparation of a dental polymerizable hydrolysis stable polycyclic amide monomer composition. The present disclosure further relates to a cured dental material obtained by polymerizing the dental material.
Patent CA-3136532-A1 (CA)
Inventor: MONTINI EUGENIO
IPC: C12Q1/6806
Filed: 2020-04-09
Abstract: A method for analysing insertion sites of an exogenous nucleotide sequence in a subject's genome, wherein the method comprises: (a) providing a sample from the subject comprising cell-free double-stranded DNA polynucleotides; (b) blunting the ends of the polynucleotides; (c) ligating an oligonucleotide to both ends of the polynucleotides; (d) amplifying polynucleotides comprising an insertion site; and (e) sequencing the product of step (d).