baber/WOPTO huggingface dataset:
Patent NZ-562595-A (NZ)
Title: Substituted amide derivatives as protein kinase inhibitors
Inventor: KIM TAE-SEONG
IPC: A61K31/435
Filed: 2006-04-27
Abstract: Disclosed are substituted amide derivatives as protein kinase inhibitors and which are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The disclosure encompasses compounds, analogs, enantiomer, diastereomer, solvate, N-oxide thereof and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The disclosure also relates to processes for making such compounds as well as to intermediates useful in such processes. These compounds may be represented by formula (II), wherein the variables are as defined in the specification.
Patent NZ-572310-A (NZ)
Title: Emulation aerosol sucker
Inventor: HON LIK
IPC: A24F40/40
Filed: 2007-05-15
Abstract: An artificial cigarette comprises a battery section, an atomizer section and a cigarette bottle section. The cigarette bottle section is inserted into the atomizer section. An external thread electrode on one end of the battery section cooperates with an internal thread electrode on one end of the atomizer section to form a screw thread electrode connecting the battery and atomizer sections. This arrangement simulates the effect of smoking, but without any danger.
Patent NZ-574189-A (NZ)
Title: Pyrrolotriazine kinase inhibitors
Inventor: FRENNESSON DAVID
IPC: A61K31/53
Filed: 2007-07-03
Abstract: Disclosed is a pyrrolo[1,2-f][1,2,4]triazin-2-yl compound of formula I where the substituents are as disclosed in the specification. Also disclosed is a pharmaceutical composition containing a compound of formula I. The compostion may also include one or more other anti-cancer or cytotoxic agents. Further disclosed is the use of a compound of formula I in the preparation of a medicament for treating proliferative disease, cancer, carcinoma of the prostate, pancreatic ductal adreno-carcinoma, breast, colon, lung, ovary, pancreas and thyroid, neuroblastoma, glioblastoma, medulloblastoma, melanoma, multiple myeloma, acute myelogenous leukemia (AML); or for the modulation of protein kinase activity including protein tyrosine kinase, CDK2/cyclin E, Flt-3, Fak, GSK-3beta, IGF-IR, IR, JAK2, Kit, Lck, Met, PDGFRbeta, PKCalpha, Src, TrkA, TrkB, VEGFR-I,vEGFR-2 and VEGFR-3; or treating IGF-1R related disorders such as cancer, diabetes, an autoimmune disease, a hyperproliferation disorder, aging, acromegaly and Crohn's disease.
Patent NZ-575093-A (NZ)
Title: Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma
Inventor: MARTIN FRANCK
IPC: C07K16/30
Filed: 2007-09-12
Abstract: Provided is an antibody or fragment thereof, which specifically binds to folate receptor-alpha (FRa), wherein said antibody or fragment thereof comprises a light chain, whose variable region comprises the complementarity-determining regions (CDRs) having the following amino acid sequences : - RASESVSFLGINLIH, QASNKDT, LQSKNFPPYT, and wherein the constant region of said light chain is a kappa constant region and a heavy chain comprising the CDRs having the following amino acid sequences DYAMI , SISSSSSYIYYADSVKG , ERYDFWSGMDV. The medicament can be used to treat cancers.
Patent NZ-582970-A (NZ)
Title: Tricyclic n-heteroaryl-carboxamide derivatives, preparation thereof and therapeutic use of same
Inventor: EVANNO YANNICK
IPC: A61P1/00
Filed: 2008-07-31
Abstract: Disclosed is a compound of formula (I) e.g. N-(6-Acetylamino-7,8-dihydro-6H-pyrrolo[2',1 ',2,3]imidazo[4,5-b]pyridin-3-yl)-5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide in which the substituents are defined in the specification in the form of a base or addition salt with an acid, and in the form of a hydrate or solvate for preventing or treating pain, inflammation, metabolic disorders, urological disorders, gynaecological disorders, gastrointestinal disorders, respiratory disorders, psoriasis, pruritis, dermal ocular or mucosal irritation, herpes, shingles, depression or diseases of the central nervous system.
Patent NZ-586461-A (NZ)
Title: Narcotic emulsion formulations comprising fentanyl for treatment of surgical pain
Inventor: NABETA KIICHIRO
IPC: A61K31/4468
Filed: 2009-04-28
Abstract: An emulsion injection formulation that comprise fentanyl, oil, water, a surfactant and an emulsion enhancer. The surfactant can be egg-yolk or soybean phospholipid and the emulsification enhancer can be oleic acid. The emulsion formulation can be used for the treatment of post-surgical pain and exhibits reduced central nervous system mediated side effects compared to fentanyl citrate.
Patent NZ-591408-A (NZ)
Title: Paracetamol and Calcium carbonate composition
Inventor: CLARKE GEOFFREY DUKE EDWARD
IPC: A61K31/16
Filed: 2009-07-29
Abstract: The present disclosure is directed to a novel preparations for reducing intrapatient variability in pharmaceutically active agent which is suitably not absorbed in the stomach, such as paracetamol, containing formulations in patients having gastric dysmotility, the preparations are also suitable for improving analgesia in a diabetic patient, or improving absorption of an active agent in a patient with gastric dysmotility, which is suitable for administering orally to said patient in need thereof a pharmaceutical dosage form comprising Paracetamol, calcium carbonate, at least one first binding agent, and at least one disintegrating agent as intragranular components in the form of a granulate, and as an extragranular component at least one hydrophilic colloid, an optionally a second binding agent, calcium carbonate, a super disintegrant, and a second active agent.
Patent NZ-593560-A (NZ)
Title: Methods of preventing or reducing oxidative stress
Inventor: BELLINVIA SALVATORE
IPC: A61K31/136
Filed: 2009-12-03
Abstract: 593560 Use of a compound of formula 1 for preparing a medicament for treating a dennatological disorder in a patient, wherein the disorder is selected from the group consisting of: psoriasis, acne vulgaris, comedo-type acne, polymorphic acne, acne rosacea, nodulocystic acne, acne conglobata, senile acne, secondary acne, solar acne, acne medicamentosa, occupational acne, ichthyosis, Darrier's disease, keratosis palmaris, keratosis plantaris, photoinduced keratosis, chronological keratosis, actinic keratosis, acne hyperseborrhoea, simple seborrhea, seborrhoeic dermatitis, and atopic dermatitis. Compounds of formula I include: 2-methoxy-3-(4'-aminophenyl) propionic acid, 2-ethoxy-3-(4'-aminophenyl) propionic acid, And 2-hydroxy-3-(4'-aminophenyl)propionic acid
Patent NZ-596615-A (NZ)
Title: Substituted isoquinoline derivative
Inventor: HIDAKA HIROYOSHI
IPC: A61K31/407
Filed: 2010-06-18
Abstract: Disclosed is an isoquinoline-6-sulfonamide derivative which is useful as a novel medicinal agent. Specifically disclosed is an isoquinoline-6-sulfonamide derivative represented by general formula (1) (wherein X and Y independently represent a direct bond, NH, CH=CH, O or S; R1 and R2 independently represent a hydrogen atom, a halogen atom, a cyano group, an alkyl group, or the like; R3 and R4 independently represent a hydrogen atom, an alkyl group, or the like, or R3 and R4 may together form an alkylene group or an alkenylene group and two carbon atoms at any positions in R3 and R4 may be crosslinked; and l, m and n independently represent a numeral value of 1 to 4), a salt of the derivative, or a solvate of the derivative or the salt.
Patent NZ-599894-A (NZ)
Title: Integrated 2d/3d camera
Inventor: CAMPBELL PATRICK
IPC: G03B3/00
Filed: 2010-10-08
Abstract: 599894 There is disclosed an integrated 2D/3D camera system which may include a 2D camera and a 3D camera affixed to the 2D camera. The 2D camera may include a first lens that is lens adjustable to set a 2D focus distance. The 3D camera may include a left camera and a right camera including respective left and right lenses, the left and right lenses synchronously adjustable to set a 3D focus distance. A focus mechanism may set the 2D focus distance and the 3D focus distance to be essentially equal by at least one of adjusting the first lens and synchronously adjusting the left and right lenses.
Patent NZ-601998-A (NZ)
Title: Substituted aza-bicyclic imidazole derivatives useful as trpm8 receptor modulators
Inventor: PARKS DANIEL
IPC: A61K31/437
Filed: 2011-03-03
Abstract: 601988 Disclosed is directed to substituted aza-bicyclic imidazole derivatives of formula (I), pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. Examples of compounds of formula (I) includes 2-(3-tert-butyl-4-chloro-1-methyl-1H-pyrazol-5-yl)-6-(2-chlorophenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine; 2-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-3Himidazo[4,5-c]pyridine hydrochloride and 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-trifluoromethylphenyl)-3H-imidazo[4,5-c]pyridine-4-carbonitrile.
Patent NZ-603737-A (NZ)
Title: Improved nail fastener
Inventor: LIU DARREN YU JEN
IPC: F16B15/06
Filed: 2012-11-20
Abstract: A nail fastener 10 comprising a shank, a head 11 and a point 13, the head 11 being at a first end of the shank and the point 13 being at a second end of the shank distal from the first end, wherein the shank comprises first means 14 for resisting outward movement of the nail fastener 10, the first means 14 being located on a first shank portion proximate to the head 11, and second means 15 for resisting outward movement of the nail fastener 10, the second means 15 being located on a second shank portion proximate to the point 13. The first means 14 and second means 15 for resisting outward movement of the nail fastener each comprise one or more ridges and/or grooves around the shank. The ridges and/or grooves of the first means 14 for resisting outward movement are oriented at substantially 90° to the shank. The ridges and/or grooves of the second means 15 for resisting outward movement are oriented at an oblique angle to the shank.
Patent NZ-612295-A (NZ)
Title: Novel 19-nor-steroids and their use for treating progesterone-dependent conditions
Inventor: PODOLSKI JOSEPH S
IPC: C07J9/00
Filed: 2011-09-08
Abstract: The disclosure relates to substituted 19-norpregna-4,9-diene-3,20-dione derivatives of formula (I), wherein the variables are as defined in the specification. These steroids are suitable for treating a progesterone-dependent condition selected from the group consisting of endometriosis and pain associated therewith, adenomyosis, endometriomas of the ovary, dysmenorrhea, uterine fibroids, endometrial hyperproliferation, ovarian cancer, and cervical cancer. Preferred route of administration of the composition comprising these steroids is via a route vaginal, intrauterine or topical, wherein the composition may be in the form of a vaginal suppository, a gel or a cream.
Patent NZ-619924-A (NZ)
Title: Combination als therapy
Inventor: CEDARBAUM JESSE
IPC: A61K31/4985
Filed: 2012-07-12
Abstract: Provided is a method for treating ALS in a subject, comprising administering to the subject a therapeutically effective amount of riluzole and a therapeutically effective amount of CK-2017357 (Tirasemtiv). Also provided are methods of reducing the variability of riluzole exposure (e.g., Cmax and/or AUC24h) in a subject, methods of reducing the variability of riluzole exposure (e.g., Cmax and/or AUC24h) between two or more subjects, methods of decreasing the total daily dose of riluzole in a subject, methods of increasing the half-life of riluzole in a subject, methods for decreasing the frequency of riluzole dosing in the subject, and methods for reducing the incidence and/or severity of adverse events in a subject treated with riluzole.
Patent NZ-631062-A (NZ)
Title: Bromodomain inhibitors
Inventor: DAI YUJIA
IPC: C07D487/04
Filed: 2014-06-27
Abstract: The disclosure relates to compounds of formula (I) wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
Patent NZ-712207-A (NZ)
Title: Tetrahydropyrrolothiazine compounds
Inventor: GREEN STEVEN JAMES
IPC: C07D513/04
Filed: 2014-03-04
Abstract: The present invention provides a compound of Formula (I): wherein R is H or F; and A is:(A), (B), (C) or (D); or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of BACE. Disclosed is the use of the compounds in the treatment or prevention of neurodegenerative diseases caused by Aβ peptides, particularly Alzheimer’s disease.
Patent NZ-729360-A (NZ)
Title: Netting material with eyelets
Inventor: JONATHAN DALLAS TOYE
IPC: D03D25/00
Filed: 2017-02-22
Abstract: A netting material formed by threads knitted or woven together, the netting material comprising a main portion comprising apertures formed between the knitted or woven threads, and has a reinforced portion comprising a first row of fastening features formed in the reinforced portion and a corresponding second row of fastening features formed in the reinforced portion, the first row of fastening features and the second row of fastening features spaced apart side-by-side so that, in use, folding the reinforced portion of the netting along a longitudinal fold line between the two rows of fastening features brings the first row of fastening features and the second row of fastening features together to form a double-layered row of fastening features. The reinforced portions are located in an outer 30% of the width of the netting material in an unfolded configuration. The double-layered row of fastening features provides a robust attachment location for securing the netting material to a support structure.
Patent NZ-731841-A (NZ)
Title: Granular fertilizer and soil conditioning formulations
Inventor: PHILLIP HALDON TAYLOR
IPC: C05D3/02
Filed: 2016-05-13
Abstract: Disclosed are granular fertilizer and soil conditioning formulations, and methods for their preparation. The granules include a combination of a binder selected from the group of alkali earth (i.e. group II metals including magnesium, calcium etc.) oxides, alkali earth hydroxides and siliceous clays (e.g. a phyllosilicate clay), and a material selected from gypsum, calcium sulfate hemihydrate, dolomite, limestone or rock phosphate. The combination enables the production of the granules by means of compaction.
Patent NZ-743813-A (NZ)
Title: Energy relay and transverse anderson localization for propagation of two-dimensional, light field and holographic energy
Inventor: KARAFIN JONATHAN
IPC: H01L31/10
Filed: 2017-07-17
Abstract: Some previously proposed approaches for holographic energy propagation may involve a compromise on image quality, resolution, angular sampling density, size, cost, safety, frame rate, etc., ultimately resulting in an unviable technology. An energy system is disclosed configured to direct energy according to a four-dimensional (4D) plenoptic function. The energy system includes a plurality of energy devices, an energy relay system and an energy waveguide system. The energy relay system has relay elements. The relay elements each have a first surface and a second surface. The second surface of the energy relay elements is arranged to form a singular seamless energy surface of the energy relay system. A first plurality of energy propagation paths extends from the energy locations in the plurality of energy devices through the singular seamless energy surface of the energy relay system. The energy waveguide system has an array of energy waveguides. A second plurality of energy propagation paths extend from the singular seamless energy surface through the array of energy waveguides in directions determined by a 4D plenoptic function.
Patent NZ-769844-A (NZ)
Title: Method of treatment of infection
Inventor: ALAWI FADIL AL
IPC: C07C49/213
Filed: 2011-01-20
Abstract: The disclosure relates to an injectable composition for the treatment of a microbial infection in a mammary gland of an animal, wherein the composition includes: (a) a non-steroidal anti-inflammatory drug (NSAID); (b) an antibiotic selected from the group consisting of a beta lactam antibiotic and macrolide antibiotic; (c) N-Methyl-2-pyrrolidone (NMP) as a solubilising agent; and (d) Propylene glycol as a carrier, wherein the amount of carrier in the composition is more than the amount of solubilising agent in the composition; wherein the solubilising agent has the property of dissolving the NSAID and/or antibiotic more readily than a carrier; and wherein the NSAID and antibiotic are dissolved in the non-aqueous solvents of N-Methyl-2-pyrrolidone and propylene glycol.
Patent PT-108402-A (PT)
Title: Extração e purificação de tricina a partir de biomassa lenhocelulósica
Inventor: ANDRÉ MIGUEL DA COSTA LOPES
IPC: C08H8/00
Filed: 2015-04-28
Abstract: A PRESENTE INVENÇÃO DESCREVE UM PROCESSO DE EXTRACÇÃO E PURIFICAÇÃO DE TRICINA A PARTIR DE BIOMASSA LENHOCELULÓSICA, QUE COMPREENDE A UTILIZAÇÃO DE LÍQUIDOS IÓNICOS COMO AGENTES DE EXTRACÇÃO E DE DUAS RESINAS POLIMÉRICAS DIFERENTES PARA POSTERIOR PURIFICAÇÃO DE TRICINA. O PROCESSO REQUER UM PROCESSAMENTO DA BIOMASSA LENHOCELULÓSICA COM LÍQUIDOS IÓNICOS E, POSSIVELMENTE, UM FRACCIONAMENTO DA BIOMASSA NAS SUAS FRACÇÕES PRINCIPAIS, NOMEADAMENTE, CELULOSE, HEMICELULOSE E LENHINA. SEGUIDAMENTE, A FASE LÍQUIDA CONTENDO LÍQUIDO IÓNICO JUNTAMENTE COM UMA MISTURA DE COMPOSTOS FENÓLICOS EXTRAÍDOS DA BIOMASSA LENHOCELULÓSICA É SUBMETIDA A UM PROCESSO DE SEPARAÇÃO ATRAVÉS DE UMA RESINA POLIMÉRICA, QUE SELECTIVAMENTE SEPARA UMA FRACÇÃO ENRIQUECIDA EM TRICINA. APÓS ESTE PASSO, A FRACÇÃO ENRIQUECIDA EM TRICINA É PURIFICADA ATRAVÉS DE UMA SEGUNDA RESINA POLIMÉRICA PARA OBTER TRICINA COM ELEVADA PUREZA. UMA VANTAGEM DESTE PROCESSO É A POSSÍVEL INTEGRAÇÃO DE UM FRACCIONAMENTO PRÉVIO DA BIOMASSA LENHOCELULÓSICA COM A VALORIZAÇÃO DE COMPOSTOS FENÓLICOS DE VALOR ACRESCENTADO, DE QUE É EXEMPLO A TRICINA, QUE PODE SER DIRETAMENTE COMERCIALIZADA.
Patent PT-110620-A (PT)
Title: Pavimento modular
Inventor: RUI PEDRO SIMÕES VICENTE
IPC: E01C5/00
Filed: 2018-03-12
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM PAVIMENTO MODULAR CONSTITUÍDO POR UM CONJUNTO DE MÓDULOS ENCAIXADOS SEQUENCIALMENTE UNS NOS OUTROS EM QUE CADA MÓDULO DO PAVIMENTO MODULAR ( 1) COMPREENDE 2 COMPONENTES, CONCRETAMENTE 1 SECÇÃO DO PAVIMENTO MODULAR (2) INTERIOR OU EXTERIOR E 1 BASE AMOVÍVEL (3), BASE AMOVÍVEL (3) ESSA QUE ESTÁ ENCAIXADA E FIXADA NA PARTE INFERIOR DA SECÇÃO DO PAVIMENTO MODULAR (2) INTERIOR OU EXTERIOR. A BASE AMOVÍVEL (3) DE CADA MÓDULO DO PAVIMENTO MODULAR (1) COMPREENDE PELO MENOS 1 ESPIGÃO VERTICAL DE FIXAÇÃO (4) QUE ESTÁ FIXADO NA FACE SUPERIOR DA BASE AMOVÍVEL (3), ESPIGÃO VERTICAL DE FIXAÇÃO ( 4) ESSE QUE SERVE PARA O ENCAIXE E FIXAÇÃO À SECÇÃO DO PAVIMENTO MODULAR (2) INTERIOR OU EXTERIOR. A BASE AMOVÍVEL (3) DE CADA MÓDULO DO PAVIMENTO MODULAR (1) COMPREENDE FUROS VERTICAIS (5) DISTRIBUÍDOS EM TODA A EXTENSÃO DA BASE AMOVÍVEL (3).
Patent RU-94002786-A (RU)
Inventor: DEKHTJAR JU D
IPC: H01L21/66
Filed: 1994-01-28
Abstract: FIELD: measurement technology. SUBSTANCE: device measuring photo-emf of semiconductors includes vacuum chamber registration unit, photostimulation unit and sample heating unit. EFFECT: improved functional reliability of device. 5 cl, 3 dwg
Patent RU-94011848-A (RU)
Inventor: DOBROVOL SKIJ V V
IPC: A61M21/00
Filed: 1994-04-13
Abstract: FIELD: medicine. SUBSTANCE: method involves applying treatment course including suggestion, reflexogenic points irritation and code fixation. After having fixed the code, temperature in occipitoparietal zone is recorded. The repeated treatment course is administered, when no pulsing changes in the temperature curve are observed. EFFECT: enhanced effectiveness of treatment.
Patent RU-94020412-A (RU)
Inventor: KISEL A I
IPC: A61B17/42
Filed: 1994-06-02
Abstract: FIELD: medicine; may be used in patient treatment and preparation of women to childbirth. SUBSTANCE: novelty consists in that fetus is turned in prenatal period without contact with devices whose operation is based on application of the offered method. EFFECT: prevention of operation of cesarean section, reduced time of patient stationary treatment, and prevention of fetus traumata.
Patent RU-94024424-A (RU)
IPC: A01H1/04
Filed: 1994-06-29
Abstract: FIELD: cotton growing. SUBSTANCE: method involves treating apical points of haploid cotton with 0.1% aqueous solution of colchicine; irradiating diploid seeds with gamma-quants for 25 sec, with charge intensity in working chamber 350 rhoentgen/sec; sowing treated seeds of seed families and selecting second generation elite plants. EFFECT: increased productivity of natural colored reddish brown fiber cotton, possessing bactericidal and other qualities in accordance with textile industry standards.
Patent RU-94027645-A (RU)
Inventor: ZHURAVLEV E N
IPC: B64C33/00
Filed: 1994-07-20
Abstract: FIELD: manufacture of aircraft; manufacture of private airplanes. SUBSTANCE: proposed flying vehicle has wings whose construction makes it possible to create required propulsive force and lift force at oscillatory motion of wings and to perform glide landing. Used as propulsive system is electromagnetic drive with control sensor following the direction of motion of wings; power supply is effected from battery-type current source. Wing flexible suspension system and electric system ensure oscillation of wing in resonance mode. General view of flying vehicle is presented in Fig.1 where: 1 - fuselage; 2 - tail boom; 3 - vertical stabilizer; 4 - horizontal control surfaces; 5 - wings; 6 - flexible suspension; 7 - movable platform, 8 - electromagnetic drive and 9 - control sensor. EFFECT: enhanced reliability.
Patent RU-94030096-A (RU)
Inventor: SHEVTSOV V I
IPC: A61B17/56
Filed: 1994-08-11
Abstract: FIELD: medicine. SUBSTANCE: method involves applying device having proximal and distal rest members connected in indirect way. Fixing unit is mounted on the distal rest member, fixing members being rods. Fixation method involves drawing external fibia malleolus with both crural bones being simultaneously rotated by means of derotaion units of the device. EFFECT: enhanced effectiveness of treatment.
Patent RU-94033720-A (RU)
Inventor: NIKOLAEV V V
IPC: C10G19/02
Filed: 1994-09-26
Abstract: FIELD: purification of petroleum products. SUBSTANCE: furnace fuel is purified from sulfurous compounds through two-step treatment with acoustic oscillations with frequency 7.2-35 kHz at 40-70 C. The 1st-step treatment is conducted in presence of alkali at fuel to alkali weight ratio from 0.007:12 to 1.14:1, whereas at the 2nd- step, air is involved in amount corresponding 0.03-0.3 parts of air per 1 part of fuel. EFFECT: enhanced efficiency. 2 cl, 1 tbl
Patent RU-94034100-A (RU)
Inventor: OSJUKHIN B A
IPC: G01S7/52
Filed: 1994-09-19
Abstract: FIELD: naval instrumentation, mainly outboard devices for shipboard navigational aids (logs, echo sounders) which may be replaced without docking the ship. SUBSTANCE: hollow body of gate valve is split in height and is provided with seal in lower portion which is mounted on ship's bottom and with shut-off element in upper detachable portion. Detachable part with shut-off element is used only in dismantling and mounting the outboard devices and is not subject to constant action of sea water. EFFECT: enhanced reliability and possibility to make gate valve from cheap materials.