baber/WOPTO huggingface dataset:
Patent AU-2015242442-A1 (AU)
Title: Multi-nozzle spray dryer, method for scale-up of spray dried inhalation powders, multi-nozzle apparatus and use of multiple nozzles in a spray dryer
Inventor: SANTOS JOSE LUIS
IPC: B01J2/04
Filed: 2015-03-30
Abstract: This present invention provides a spray dryer for use in preparing particles for inhalation, the spray dryer comprising a multi-nozzle apparatus comprising multiple single nozzles suitable for use in preparing inhalation powders and with a drying gas flow rate greater than about 80 kg/h. Also provided is a method for scaling-up a spray drying process for preparing particles for inhalation from a smaller scale spray dryer to a larger scale spray dryer, relative in size to each other, the method comprising the use in the larger scale spray dryer of a multi-nozzle apparatus comprising single nozzles suitable for use in preparing inhalation powders, wherein the number of nozzles in the larger spray dryer is determined by the ratio of the drying gas flow rate of the larger scale spray dryer to the drying gas flow rate of the smaller scale spray dryer. Also provided is a multi-nozzle apparatus produced from the method of the present invention, the multi-nozzle apparatus comprising multiple single nozzles suitable for use in preparing inhalation powders. Also provided is the use of multiple single nozzles suitable for use in preparing inhalation powders in a spray dryer with a drying gas flow rate greater than about 80 kg/h. The nozzles used in the present invention preferably prepare particles with a mean particle size less than about 5 microns.
Patent AU-2015250059-A1 (AU)
Title: System and method for maintenance and monitoring of filtration systems
Inventor: PATEL HEMANG R
IPC: G05B23/00
Filed: 2015-04-20
Abstract: Aspects of the present disclosure are directed toward methods, apparatuses and systems for operating at a fluid-maintenance site. In certain embodiments, the methods, apparatuses, and systems include a fluid filter, a sensor that provides parameters that characterize fluid flowing through the fluid filter, and a wireless interface circuit. The wireless interface circuit operates in a set-up mode and a normal-operation mode. In the set-up mode, the wireless interface circuit operates by communicating authentication data with a mobile data-processing device while the mobile data-processing device is proximate to the fluid-maintenance site. In the normal-operation mode, the wireless interface circuit operates by sending the parameters wirelessly, according to the authentication protocol, to a remotely-situated server via a wireless communication medium and a broadband connection.
Patent AU-2015329965-A1 (AU)
Title: Bispecific antibodies against CD3epsilon and ROR1
Inventor: VU MINH DIEM
IPC: A61P35/00
Filed: 2015-10-08
Abstract: The present invention relates to bispecific antibodies against ROR1 and CD3, their manufacture and use.
Patent AU-2015330945-A1 (AU)
Title: Tamping machine for compacting the ballast bed of a track
Inventor: LICHTBERGER BERNHARD
IPC: E01B27/17
Filed: 2015-10-06
Abstract: The invention relates to a tamping machine (22) for compacting the ballast bed of a track, said machine comprising at least two tamping units (37, 38, 41) for each side of the tamping machine, which units can be displaced transversely relative to the longitudinal direction of the tamping machine by means of a transversal displacement device. At least two guides, in particular motion bars or sliding tubes (2, 3) are associated with both tamping units (37, 38) of each side of the tamping machine, said guides being offset in relation to one another with respect to their height and in the longitudinal direction of the tamping machine. Each outer tamping unit (37) and its associated guides can be displaced transversely to the longitudinal direction of the tamping machine using an adjusting drive (21) and the inner tamping unit (38) can be displaced on the same guides, independently of the outer tamping unit (37), transversely to the longitudinal direction of the tamping machine using an adjusting drive (21).
Patent AU-2015341803-A1 (AU)
Title: Extruded pet food product
Inventor: DANSET GAETAN
IPC: A23K40/25
Filed: 2015-11-03
Abstract: The present invention relates to an extruded pet food product for use in pet animal health. The present invention relates to an extruded packaged pet food product containing from over 15% to 30% moisture, from 11 % up to 45% carbohydrate, fat and protein, an aw of over 0.7, for use in pet animal health. The invention also relates to a method of health in an animal, the method comprising feeding an extruded packaged pet food product containing from over 15% to 30% moisture, from 11% up to 45% carbohydrate, an aw of over 0.9, and a density in the range of 250 to 300 g/l to a pet animal.
Patent AU-2015348198-A1 (AU)
Title: Use of antibodies for enrichment of engineered T cells with exogenous immune receptors and antibodies for use in depletion of engineered T cells
Inventor: KUBALL JURGEN HERBERT ERNST
IPC: A61K35/17
Filed: 2015-11-20
Abstract: The current invention now provides for exogenous immune receptors that do not require any additional selection marker genes and/or any additional suicide genes. The invention now allows for the production of engineered T cells that can be enriched for in an untouched manner, i.e. the engineered T cells do not require any interaction with any outside agent and can selected for by eliminating T cells that express the endogenous alpha beta T cell receptor. Engineered T cells with an exogenous immune receptor are provided that can be differentiated from endogenous T cell receptor and now can be eliminated, i.e. depleted, with a selective antibody that specifically targets the exogenous immune receptor.
Patent AU-2015365167-A1 (AU)
Title: Anti-C5 antibodies and methods of use
Inventor: RUIKE YOSHINAO
IPC: C12N5/10
Filed: 2015-12-18
Abstract: An objective of the invention is to provide anti-C5 antibodies and methods of using the same. The invention provides anti-C5 antibodies and methods of using the same. In some embodiments, an isolated anti-C5 antibody of the present invention binds to an epitope within the beta chain of C5 with a higher affinity at neutral pH than at acidic pH. The invention also provides isolated nucleic acids encoding an anti-C5 antibody of the present invention. The invention also provides host cells comprising a nucleic acid of the present invention. The invention also provides a method of producing an antibody comprising culturing a host cell of the present invention so that the antibody is produced. The invention further provides a method of producing an anti-C5 antibody comprising immunizing an animal against a polypeptide which comprises the MG1-MG2 domain of the beta chain of C5. Anti-C5 antibodies of the present invention may be for use as a medicament.
Patent AU-2015372368-A1 (AU)
Title: Mineralization fluoride compositions
Inventor: REYNOLDS ERIC CHARLES
IPC: A61K6/838
Filed: 2015-12-24
Abstract: The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided.
Patent AU-2015413017-A1 (AU)
Title: Method and identification kit for identifying sensitizing drug for drug allergic reaction
Inventor: CHUNG WEN-HUNG
IPC: C12Q1/68
Filed: 2015-10-30
Abstract: Disclosed are a method and an identification kit for identifying a sensitizing drug for a drug allergic reaction, comprising: first, biological sample lymphocytes and a suspicious drug or the metabolites thereof are co-cultured in vitro to form reactants, and then the expression levels of the granulysin protein, polypeptide or mRNA in the reactants are detected and compared with the control values, then the degree that the suspicious drug or the metabolites thereof activate lymphocytes can be identified, thus identifying the sensitizing drug that initiates the drug allergic reaction. The sensitizing drug comprises Western medicine, traditional Chinese medicine, a vaccine and an antigen molecule that can cause T-cell activation, and therefore, the present invention has excellent properties such as a single, easy-to-execute technique, being quick, economic, and having a high sensitivity and high specificity and so on.
Patent AU-2015414199-A1 (AU)
Title: Production of in vivo N-deglycosylated recombinant proteins by co-expression with Endo H
Inventor: MAMMEDOV TARLAN
IPC: C07K14/36
Filed: 2015-11-13
Abstract: Plants have emerged as an alternative expression system and are increasingly being used byindustry and academia for producing target proteins. However, the ability of plants to glycosylate proteins can be a significant limitation for those proteins, which do not require N- glycosylation. For example, Plasmodium falciparum proteins, or A chain of human factor XIIIdo not carry N-linked glycans, or the protective antigen (PA) of Bacillus anthracisis not a glycoprotein; however, these proteins contain potential N-linked glycosylation sites that can be aberrantly glycosylated during expression in yeast, mammalian, or plant systems, potentially leading toreduced functionality and immunogenicity because of incorrect⁄altered folding and⁄or masking of epitopes. To overcome this problem we have recently developed a strategy of enzymatic deglycosylation of proteins in vivo by co-expressing with bacterial PNGase F (Peptide: N-glycosidase F) using transient expression in plants (WIPO Patent Application WO/2012/170678), which allowed production of malaria vaccine candidate Pfs48/45, which can provide ahigh transmission blocking (TB) activity (Mamedov et al., 2012). In addition, other deglycosylated antigens induced significantly higher levels of toxin-neutralizing antibody responses in mice than compared with glycosylated forms (Mamedov et al, manuscript has been submitted). Although a PNGase F treatment (in vivodeglycosylation) removes the oligosaccharide intact, but causes amino acid change in the deglycosylated protein due to deamidation of the asparagine (N) in the NxS/T site (sequence) into an aspartate (D). In this study, a strategy was developed for production of target proteins in plants in non-N-glycosylated form, but with no amino acid change in the NxS/T site of the resulting deglycosylated proteins, which can provide production of non-N- glycosylated recombinant proteins in plants or other eukaryotic system with a native-like fold. Thus, materials and methods for in vivo de- glycosylation of recombinant N-glycosylated proteins by co-expression with Endo-β-N- acetylglucosaminidase H (Endo H) in plants, using a transient expression system are described in this invention. A method of expressing active Endo Hin plants is also provided.
Patent AU-2016200002-A1 (AU)
Title: High dynamic range transition
Inventor: DOEPKE FRANK
IPC: H04N5/235
Filed: 2016-01-04
Abstract: In personal electronic devices including digital imaging capability, methods, devices and computer readable media are described for determining when image capture operations may benefit from using high dynamic range imaging (HDRI) operations. In general, techniques are disclosed for analyzing an image's luminosity and/or color/tonal histograms to automatically determine when HDRI operations can benefit scene capture. If the determination that HDRI operations can improve scene capture, the user is so notified.
Patent AU-2016202302-A1 (AU)
Title: Method and apparatus for patterned plasma-mediated laser trephination of the lens capsule and three dimensional phaco-segmentation
Inventor: ANDERSEN DAN E
IPC: A61B18/18
Filed: 2016-04-13
Abstract: Abstract A system for ophthalmic surgery comprising a pulsed laser system, an optical coherence tomography imaging assembly, a scanning assembly to position the laser to a location in one or more floaters in the posterior pole of the eye and a control system operably coupled to the laser system and configured to scan the eye to create a profile of tissues in the posterior pole, identify boundaries of the one or more floaters, identify treatment regions based upon the boundaries and dissect tissue in the treatment regions with the pulsed laser.
Patent AU-2016202341-A1 (AU)
Title: Surgical instrument with articulation assembly
Inventor: SRINIVAS JITENDRA BHARGAVA
IPC: A61B1/005
Filed: 2016-04-14
Abstract: SURGICAL INSTRUMENT WITH ARTICULATION ASSEMBLY Abstract A surgical instrument (10a) includes an elongate body (102), a toothed rack (134), and an end effector (110). The elongate body (102) has a proximal end (102a) and a distal end (102b) and defines a first longitudinal axis (X1). The toothed rack (134) is disposed within the elongate body (102) and is movable in a direction parallel to the first longitudinal axis (X1). The end effector (110) has a proximal end pivotally supported on the distal end (102b) of the elongate body (102). The end effector (110) defines a second longitudinal axis (X2) and supports a gear (142) operatively associated with the rack (134). Longitudinal movement of the rack (134) effects pivotal movement of the end effector (110) relative to the elongate body (102) from a first position to a second position. In the first position, the second longitudinal axis (X2) is aligned with the first longitudinal axis (X1). In the second position, the second longitudinal axis (X2) is misaligned with the first longitudinal axis (X1). CCu C- V.P
Patent AU-2016228041-A1 (AU)
Title: Truss frame, modular truss girder and bridging and/or support construction
Inventor: KRELLER HELMUT
IPC: E04G1/14
Filed: 2016-01-27
Abstract: The invention relates to a truss frame (20) for constructing a bridging and/or support construction, which truss frame consists of multiple, rod-shaped individual metal parts, namely consisting of two elongated, parallel post pipes (21), each extending in the direction of its longitudinal axis and having an outer circumference (44); two parallel crossbars (22), each extending in the direction of its longitudinal axis and perpendicularly to the post pipes; and an elongated diagonal element (23) that is adjustable in length, which individual parts are hingedly connected to one other by means of bolts (24) such that said parts can be detached from one another. Two parallel connecting plates (36.1, 36.2) are secured in the region of each post pipe end (33.1, 33.2) of the post pipes (21), which plates are disposed on a common, imaginary plane that contains the longitudinal axes of the post pipes (21) and the crossbars (22) and which plates extend away from one another. Each crossbar (22) has crossbar ends (35.1, 35.2) that face away from one another, each of the crossbar ends being hingedly and detachably secured to a connecting plate (36.1, 36.2) of the connecting plates (36.1, 36.2) by means of a bolt (24). The diagonal element (23) has diagonal element ends (61.2, 62.2) that face away from one another, each of the diagonal element ends being hingedly and detachably secured to a connecting plate (36.1, 36.2) of the connecting plates (36.1, 36.2) by means of a bolt (24). At least two rosettes (50) are firmly welded to each post pipe (21) at a distance from one another that corresponds to an integer multiple of a modular size of a module scaffold. A connecting body (41, 57) is firmly welded in the region of at least two post pipe ends (33.1, 33.2), each associated with the same crossbar (22), of the post pipes (21), which body completely surrounds the outer circumference (44) of the respective post pipe (21). Each of the two connecting plates (36.1, 36.2) that are secured in the region of said post pipe ends (33.1, 33.2) is firmly welded to at least the respective connecting body (41, 57).
Patent AU-2016244106-A1 (AU)
Title: Compounds and methods for modulating TMPRSS6 expression
Inventor: GUO SHULING
IPC: A61K45/00
Filed: 2016-04-04
Abstract: Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an individual in need thereof. Iron accumulation diseases in an individual such as polycythemia, hemochromatosis or β-thalassemia can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to TMPRSS6.
Patent AU-2016252892-A1 (AU)
Title: Compounds for treating pruritic conditions
Inventor: HAWI AMALE
IPC: C07D491/044
Filed: 2016-04-22
Abstract: The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvates, and/or esters thereof. These compounds are useful for treating itch or a pruritic condition. The present invention also includes compositions comprising the present compounds and methods of treating a pruritic condition. Furthermore, the present invention provides methods for preparing the compounds.
Patent AU-2016259315-A1 (AU)
Title: Rasagiline for parkinson's disease modification
Inventor: LEVY RUTH
IPC: A61K31/135
Filed: 2016-11-15
Abstract: A method for modifying Parkinson's disease by periodically administering a pharmaceutical composition comprising a therapeutically effective amount of rasagiline or a pharmaceutically acceptable salt of rasagiline to the patient, thereby modifying the disease. The method includes reducing the rate of progression; delaying the need for symptomatic anti-Parkinsonian therapy; reducing the risk of a Parkinson's disease patient requiring symptomatic anti-Parkinsonian therapy; and reducing the functional decline.
Patent AU-2016272843-A1 (AU)
Title: Fast cure epoxy resin compositions
Inventor: ASPIN IAN
IPC: C08J5/04
Filed: 2016-06-02
Abstract: Disclosed herein is an epoxy resin compositions comprising an epoxy component and a curing agent component, wherein the curing agent component is at least an ammoalkylirnidazole curing agent, and wherein the epoxy component and the curing agent component react together at a temperature of about 100°C to about 130°C to form a substantially cured reaction product in about 10 minutes or less. Further disclosed are composite products formed from such epoxy resin compositions.
Patent AU-2016282579-A1 (AU)
Title: Extended message signaled interrupts (MSI) message data
Inventor: ROSENBERG OFER
IPC: G06F13/24
Filed: 2016-06-17
Abstract: Extended message signaled interrupts (MSI) data are disclosed. In one aspect, MSI bits are modified to include a system level identifier. In an exemplary aspect, an upper sixteen bits of the MSI message data are modified to be the system level identifier. By providing the system level identifier within the MSI message data, an interrupt controller can verify the interrupt source.
Patent AU-2016307230-A1 (AU)
Title: Compounds
Inventor: BRAND STEPHEN
IPC: A61P33/02
Filed: 2016-08-03
Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).
Patent AU-2016328789-A1 (AU)
Title: Aircraft wing structure
Inventor: ELSON ANDREW CHARLES
IPC: B64C3/24
Filed: 2016-09-19
Abstract: An aircraft has a wing providing the main lifting surface for the aircraft. The wing has a structure supporting an aerodynamic surface, and the wing has a weight, the wing structure being unable to support its own weight when the aircraft is stationary and under a load of 1g so as to cause structural failure of the wing.
Patent AU-2016331957-A1 (AU)
Title: Multi-active-axis, non-exoskeletal rehabilitation device
Inventor: TOWNSEND WILLIAM T
IPC: A61F2/72
Filed: 2016-09-30
Abstract: A robotic device for operation in association with an appendage of a user, wherein the appendage of the user has an endpoint, the robotic device comprising: a base; and a robotic arm attached to the base and having an endpoint, the robotic arm having at least two active degrees of freedom relative to the base and being configured so that when the base is appropriately positioned relative to a user, the reference frame of the robotic device is oriented generally similarly to the reference frame of the user and motions of the endpoint of the appendage of the user are mimicked by motions of the endpoint of the robotic arm.
Patent AU-2016393252-A1 (AU)
Title: Dynamic application execution for automobile and cloud hybrid environments
Inventor: SNYDER IRA
IPC: G06F17/00
Filed: 2016-12-21
Abstract: Embodiments are directed towards providing a dynamic application environment where separate components of an application can execute on separate processing hardware at any given point in time. A host device monitors current operating characteristics associated with a computing device, such a head unit of an automobile, and based on those characteristics selects which components of one or more applications to execute on the computing device and which components to execute on the host device, if any. The host device provides the selected components to the computing device for execution by the computing device and the host device executes any other components that are not executed by the computing device. The host device monitors the current operating characteristics associated with the computing device, and modifies the selection of which components are executing on which device based on changes in current operating characteristics.
Patent WO-2018068089-A1 (WO)
Title: Laser de traitement à miroir à retour instantané
Inventor: BARRETT BRADLEY
IPC: A61F9/008
Filed: 2017-10-11
Abstract: La présente invention concerne un système laser ophtalmique permettant de générer un premier faisceau à une première longueur d'onde sur un premier trajet optique et un second faisceau à une seconde longueur d'onde sur un second trajet optique, et d'orienter les composants optiques pour orienter sélectivement le premier faisceau ou le second faisceau vers un trajet optique de traitement. Le système laser ophtalmique comporte un illuminateur coaxial à retour instantané comprenant un miroir à retour instantané mobile sur un axe allant d'une position hors du trajet optique de traitement vers une position dans le trajet optique de traitement pour orienter l'éclairement dans un trajet d'éclairage coaxial avec le trajet optique de traitement. Le miroir à retour instantané est conçu pour émettre un faisceau qui suit le second trajet optique.
Patent WO-2018081863-A1 (WO)
Title: Dérivés à substitution en position 6 de l'hexaméthylène amiloride en tant qu'inhibiteurs de upa et leurs utilisations
Inventor: KELSO MICHAEL
IPC: A61P35/00
Filed: 2017-11-02
Abstract: La présente invention concerne, d'une manière générale, des dérivés à substitution en position 6 de l'hexaméthylène amiloride, leur préparation et leur utilisation dans le traitement de maladies, tel que le cancer.
Patent AU-2017201204-A1 (AU)
Title: Modular lift
Inventor: KALINOWSKI DANE GIN MUN
IPC: B66F9/06
Filed: 2017-02-22
Abstract: A lift for a fork tine assembly includes a generally upright frame having at least one handle grip portion at a rearward portion thereof. The handle grip portion is fixed relative to the frame. A lift mechanism is secured to the frame. The lift mechanism is capable of attaching to and raising and lowering at least one fork tine. A plurality of wheels support the frame. The at least one fork tine may be part of a first fork tine assembly that can be selectively removed from the lift and replaced with a different configuration fork tine assembly. An optional shelf is provided on the frame for convenience but may be pivoted out of the way when not in use.
Patent AU-2017201446-A1 (AU)
Title: A2a antagonists as cognition and motor function enhancers
Inventor: BANDAK STEPHEN I
IPC: A61K9/00
Filed: 2017-03-02
Abstract: A2A ANTAGONISTS AS COGNITION AND MOTOR FUNCTION ENHANCERS Methods are described for inducing cognition and motor function enhancement in patients suffering from Parkinson's disease by administering an effective amount of an Adenosine 2a antagonist. The Adenosine 2a antagonist can optionally be administered in combination with a dopamine precursor, such as levodopa, or a dopamine receptor agonist. - 1-