baber/WOPTO huggingface dataset:
Patent NZ-518915-A (NZ)
Title: Peptide mimics of conserved gonococcal epitopes and methods and compositions using them for immunizing against Neisseria gonorrhoeae
Inventor: RICE PETER A
IPC: C07K14/22
Filed: 2000-10-27
Abstract: A peptide mimic of a conserved gonococcal epitope not found on human blood group antigens and capable of inducing in a mammal an immune response against the conserved gonococcal epitope comprises the amino acid sequence DE_GLF. Also described is a peptide mimic which immunospecifically binds to an antibody that binds to an oligosaccharide of N. gonorrhoeae, which epitope is not present in human blood group antigens and comprises the amino acid sequence DE_GLF. The peptide mimic can further bind the monoclonal antibody 2C7. A composition for immunizing against an N. gonorrhoeae infection can comprises the peptide mimics described above or the peptide mimics comprising the sequence of SEQ ID NO:1-6 and 10. The peptide mimic can be further coupled to the complement protein C3d which increases the antigenicity of the peptide mimic.
Patent NZ-519638-A (NZ)
Title: Substituted acylhydroxamic acids and methods of reducing TNF alpha levels
Inventor: MAN HON-WAH
IPC: A61P37/06
Filed: 2000-12-19
Abstract: A  chirally pure (R) or chirally pure (S) or a mixture of  (R) or (S) acylhydroxamic acid derivative or an addition salt thereof has the formula (I) wherein: the  carbon  atom  designated  *  constitutes  a  center  of chirality; R4 is hydrogen or- (C=O)-R12; R1  and  R2 independently are alkyl, phenyl, benzyl, pyridyl methyl,    pyridyl,    imidazloyl,   imidazolylmethyl,    or CHR*(CH2)nNR*R0; R*and  R0 independently are hydrogen, alkyl, phenyl, benzyl, pyridylmethyl, pyridyl, imidazloyl or imidazolylmethyl; n is 0 to 2; R5 is C=O, CH2, CH2-CO-, or SO2; R6  and  R7 independently are nitro, cyano, trifluoromethyl, carbethoxy,  carbomethoxy, carbopropoxy, acetyl,  carbamoyl, acetoxy,    carboxy,   hydroxy,   amino,   alkyl,    alkoxy, cycloalkoxy,   halo,   bicycloalkyl,   tricycloalkoxy,    1- indanyloxy,    2-indanyloxy,   -cycloalkylidenemethyl,    or alkylidenemethyl; R8,  R9, R10 and R11 are independently (i) hydrogen,  nitro, cyano,     trifluoromethyl,    carbethoxy,     carbomethoxy, carbopropoxy, acetyl, carbamoyl, acetoxy, carboxy,  hydroxy, amino,  alkylamino, dialkylamino, acylamino,  alkyl,  alkoxy halo,  or (ii) one of R8, R9, R10 and R11 is acylamino,  and the  remaining of R8, R9, R10 and R11 are hydrogen, or (iii) hydrogen  if R8 and R9 taken together are benzo,  quinoline, quinoxaline,      benzimidazole,      benzodioxole,       2- hydroxybenzimidazole, methylenedioxy, dialkoxy  or  dialkyl, or  (iv)  hydrogen if R10 and R11 taken together are  benzo, quinoline,  quinoxaline,  benzimidazole,  benzodioxole,   2- hydroxybenzimidazole, methylenedioxy, dialkoxy, or  dialkyl, or (v) hydrogen if R9 and R10 taken together are benzo. The compounds are useful in treating cancer or inflammation.
Patent NZ-521773-A (NZ)
Title: Use of formulations for hydrophobic pharmaceutical agents in treatment or prevention of cell proliferative disorders
Inventor: SHENOY NARMADA
Filed: 1998-03-04
Abstract: A use, in the manufacture of a medicament for preventing or treating a cell proliferative disorder in a human patient in need of treatment, of a diluted parenteral formulation comprising one or more hydrophobic pharmaceutical agents, wherein said agents are independently selected from the group consisting of a quinazolin-, a nitrothiazole- and an indolinone-based compound; one or more polyoxyhydrocarbyl compounds; and one or more pharmaceutically acceptable surfactants; wherein said indolinone-based compound is an indolinone-based compound of formula (VI) at a concentration of about 0.1 to about 100 mg/nil; wherein R1, R2, R3, R4 are selected from the group consisting of hydrogen, trihalomethyl, hydroxyl, thioether, cyano, alkoxy, aikyl, amino, bromo, fluoro, chioro, iodo, mercapto, thio, cyanoamido, aikylthio, aryl, heteroaryl, carboxyl, ester, oxo, alkoxycarbonyl, aikenyl, alkoxy, nitro, alkoxyl, and amido moieties; and R5 is an optionally substituted aryl or heteroaryl cyclic moiety; wherein at least one or said surfactants for the indolinone-based compound is PEG-400 at a concentration of about 0.01 to about 10 g/ml and at least one of said polyoxyhydrocarbyl compounds for the indolinone-based compound is ethoxylated castor oil at a concentration of about 0.01 to 10 g/ml.
Patent NZ-521789-A (NZ)
Title: Functional probe library and apparatus for identifying the previously unidentified biological function of target proteins
Inventor: PANTOLIANO MICHAEL W
IPC: G01N25/12
Filed: 1998-11-12
Abstract: Described is a functional probe library comprising a multiplicity of discrete compounds such as vitamins, coenzymes, metal chelators, metal ions, carbohydrates, nucleic acids, lipids, enzymes, steroids, amine hormones, alkaloids, generic drug molecules and compounds having amino acid residue functional groups, for determining at least one previously unidentified biological function of a target protein. The library has a sufficient diversity of compounds to determine at least one previously unidentified biological function of the target protein. The compounds are tested for their ability to modify the stability of the target protein and are compared with a list of compounds known to modify the stability of a group of proteins which share biological function. Also described is an assay apparatus comprising a heating block in contact with a microtitre plate, in which the samples comprising the target protein and one or more of a multiplicity of discrete compounds are placed. Also attached is a light source, a fluorescent emission sensor and a means for processing the spectral emission signal generated. The apparatus has the ability to detect the shift in the thermal unfolding curve of the target protein and the results are compared with the results from a list of compounds that are known to modify the stability of a group of proteins which share biological function.
Patent NZ-530161-A (NZ)
Title: Positive modulators of nicotinic receptor agonists
Inventor: GURLEY DAVID
IPC: C07D407/12
Filed: 2000-11-01
Abstract: Disclosed are compounds of formula I, wherein: R1 and R3 are independently H or alkyl, R2 is H, alkyl or CH2CN, R4 is H, alkyl, alkenyl, alkynyl, CH2C(W)=CH2, (CH2)nAr, CH2CH=CHAr, CH2COPh, CH2CONHAr, C(U)NH(CH2)mAr, or (CH2)dY(CH2)eAr, U is O or S, W is halogen, X and Y are independently O, S or NR5, R5 is H, alkyl, alkenyl or together R3 and R5 form a ring, n and m are independently 0-4, d is 1-3, e is 0-1, Ar is optionally substituted phenyl, naphthyl or furan, The compounds are used in the manufacture of medicaments for use as positive modulators of nicotinic receptor agonists. (62) Divided out of 518450
Patent NZ-530758-A (NZ)
Title: Process for forming polymer structures containing an oxygen sensor for multi layered oxygen sensitive food packaging film
Inventor: PUTNAM DAVID
IPC: G01N31/22
Filed: 2002-06-24
Abstract: There is disclosed a process for melting a luminescent oxygen sensitive compound into extruded polymer films. Specifically, there is disclosed a process for thermal melting of oxygen-sensitive indicators into common packaging polymers used for commercial packaging of products, such as foods. The oxygen-sensitive indicators can be used for real-time monitoring of oxygen in commercial packaging operations. Particularly disclosed is a process for making an oxygen-sensitive polymeric structure, comprising (a) adding an oxygen-sensitive indicator to a thermoplastic polymeric material heated to just above its melting temperature; (b) mixing the oxygen-sensitive indicator thoroughly within the thermoplastic polymeric material while continuing the heating to maintain the thermoplastic polymeric material in a substantially liquid form; and (c) forming the mixture into an end product form of indicator-polymer product.
Patent NZ-531454-A (NZ)
Title: Mutated protein and nucleotide sequences for the p62 / SQTM1 protein and use in treating and detecting Paget disease of the bone
Inventor: BROWN JACQUES
IPC: C12Q1/68
Filed: 2002-07-30
Abstract: Described is a method for detecting a condition such as Paget disease of the bone that is associated with a mutated p62/SQSTM1 protein which comprises assaying a sample for: (a) a nucleic acid encoding the mutated p62/SQSTM1 protein having the nucleotide sequence shown in SEQ ID NO: 3, or a fragment which comprises nucleotide position 1215 shown in SEQ ID NO: 3; or (b) a protein having the sequence shown in SEQ ID NO:4, or a fragment that comprises amino acid position 392 shown in SEQ ID NO:4. Also described is a nucleic acid molecule that encodes a p62/SQSTM1 protein, an expression vector comprising the nucleic acid molecule, a non-human host cell transformed with the expression vector, and an antibody that binds to the protein.
Patent NZ-532777-A (NZ)
Title: An apparatus and method for beating and rolling a food dough belt
Inventor: HAYASHI TORAHIKO
IPC: A21C3/02
Filed: 2003-09-01
Abstract: Conventionally, it has been necessary to use abundant dusting powder to prevent food dough from adhering to a rolling apparatus. A plurality of rolling rollers (11r) move sequentially upstream from downstream or downstream from upstream along the food dough belt (9), while each rolling roller rotates on its own axis. The moving direction (A) of the rolling roller is changed according to technical requirements. The number of beats is regulated by changing the moving speed (V1) of the rolling roller. Further, the peripheral speed of the rolling roller is made to be equal to or almost equal to the surface speed of the food dough belt by changing the rotating speed (V2) of the rolling roller. Therefore it is possible to reduce the amount of dusting powder and also to make the internal phase of bread dough uniform.
Patent NZ-535804-A (NZ)
Title: A self programming computer controlled centerless grinding machine
Inventor: SMARSH STEVEN G
IPC: B24B51/00
Filed: 2003-03-18
Abstract: A computer controlled grinding machine to be run by a machine operator, comprising: a machine base; a workpiece support rotatable about spindle having a first rotational axis; a workpiece mounting attached to the workpiece support for securing the workpiece; a grinding wheel for grinding the workpiece; a regulating roller mounted on the spindle, the regulating roller for supporting and rotating the workpiece; a first rotating motor for rotating the workpiece about the first rotational axis; a second rotating motor for rotating the workpiece about the second rotational axis; and a computer controlled by computer software to direct the rotation and location of the first and second rotational axes; wherein the computer emits audio controls to the operator requesting the input of various data entries into the computer to correspond with a desired resultant product from the workpiece, whereby the computer programs itself to a desired configuration based upon the data entries.
Patent NZ-537309-A (NZ)
Title: Method and system for improving vision
Inventor: LIEBERMAN DAVID M
IPC: A61F2/16
Filed: 2003-06-03
Abstract: Methods and apparatus are disclosed for analysing vision of an eye and producing a modified model of the cornea for planning restructuring of the eye. The modification is in a manner which does not interfere with the natural shape of the cornea or its orientation relative to the remainder of the eye, but which changes its surface curvature appropriately to achieve the required correction of vision. The focus of the cornea is adjusted so that different regions focus substantially to the same axis and preferably to substantially the same point on the axis. The cornea model can represent a reshaping of the cornea (e.g. through ablation) or application of an appropriate contact lens or other optical lens. In either case, correcting the central portions of the cornea should have a more significant effect on correcting focus scatter than correcting the more outward portions.
Patent NZ-539337-A (NZ)
Title: Novel gum application in wheyless cream cheese systems
Inventor: CHA ALICE SHEN
IPC: A23C19/076
Filed: 2003-08-01
Abstract: Disclosed is a wheyless cream cheese or wheyless cream cheese-like product comprising 3-15 percent dairy protein, 4-35 percent fat, 0.01-1 percent gum, and 40-80 percent water. The gum is added in a first portion and a second portion, wherein the first portion is an ionic gum at 0.001-0.1 percent which is added prior to culturing or acidification of the wheyless cream cheese or wheyless cream cheese-like product. The second portion of the gum is a stabiliser added after culturing or acidification of the wheyless cream cheese product. The wheyless cream cheese product has a firmness greater than 1000 pascals. (62) Divided Out of 527370
Patent NZ-540623-A (NZ)
Title: Collagen and method for producing same
Inventor: SNOWDEN JOHN
IPC: A61K38/00
Filed: 2003-05-20
Abstract: Described herein is a method for producing collagen from a mammalian animal skin comprising applying to the skin an organic acid buffer and incubating the skin for a sufficient time to loosen attached wool or hair; and extracting the collagen from the skin. Optionally a step of mincing or chopping the skin to produce skin pieces may also be included in the said method. Also disclosed are preferential time and temperature ranges of incubation, as well as effective pH ranges of the organic buffer.
Patent NZ-541052-A (NZ)
Title: Method for mounting a rotor blade of a wind energy installation without using a crane
Inventor: WOBBEN ALOYS
IPC: F03D1/00
Filed: 2003-11-07
Abstract: Mobile cranes have been used to mount rotor blades on wind energy installations for a long time. Such cranes pick up the rotor blade at the foot of the wind energy installation and guide it up to the rotor blade connection of the hub of the wind energy installation, so that the rotor blade can be connected to the hub. Said connection is carried out mostly by screwing, in that screw bolts are countersunk in the connecting flange of the rotor blade and project into corresponding boreholes in the rotor blade connection of the hub, in such a way that nuts can be screwed onto the screw bolts. The invention relates to a method for mounting blades according to patent claim 1. Advantageous developments are described in the following claims. The inventive method is used to mount a rotor blade (12) of a wind energy installation (1) onto a rotor blade connection (9) on a hub (8) of a rotor (5) of the wind energy installation (1), or to dismount said rotor blade from the same, without using a crane. According to said method, at least one cable (14, 15) is fixed between a part in the hub region (8) of the wind energy installation and the bottom (13) of the wind energy installation (1), and the rotor blade (12) is moved upwards along the cable (14, 15) when mounted and downwards along the cable when dismounted.
Patent NZ-544119-A (NZ)
Title: Tablet comprising fluvastatin and carmellose calcium
Inventor: UEHARA TOMOYUKI
IPC: A61K31/405
Filed: 2004-06-24
Abstract: The disclosure relates to a fluvastatin-containing tablet, particularly a fluvastatin containing tablet which has excellent disintegrating property and good bioavailability. Fluvastatin has a generic name, R*,S*-(E)-(+)-7-[3-(fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid. The fluvastatin-containing tablet is characterized in comprising a fluvastatin compound, particularly fluvastatin sodium, and carmellose calcium as a disintergrating agent.
Patent NZ-547794-A (NZ)
Title: Pyrido- and pyrimidopyrimidine derivatives as anti-proliferative agents
Inventor: FREYNE EDDY JEAN EDGARD
IPC: C07D471/04
Filed: 2004-12-15
Abstract: Disclosed is a compound of formula (I), or an N-oxide, pharmaceutically acceptable addition salts, and stereoisomers thereof, wherein a1-a2=a3-a4 is N-CH=CH-CH, N-CH=N-CH, or CH-CH=N-CH, Z is O, NH, or S, and wherein the other substituents are as defined in the specification. Also disclosed is a method of making the compound, and the intermediates therein. Also disclosed is the use of the compound as a kinase inhibitor, and for treating atherosclerosis, restenosis, and cancer.
Patent NZ-555571-A (NZ)
Title: Alpha thymosin peptides as cancer vaccine adjuvants
Inventor: MOVIGLIA GUSTAVO ANTONIO
Filed: 2005-12-06
Abstract: Disclosed is a pharmaceutical combination for treatment of cancer in a subject and for enhancing cancer vaccine effectiveness in the subject, comprising: a) an immune response-triggering cancer vaccine capable of eliciting an immune system response in said subject; and b) a vaccine effectiveness-enhancing amount of an alpha thymosin peptide, which enhances said immune system response in said subject; c) wherein said cancer vaccine and said alpha thymosin peptide can be administered separately or together.
Patent NZ-556412-A (NZ)
Title: A pant-type absorbent article
Inventor: WENNERBACK MARGARETA
IPC: A61F13/15
Filed: 2005-03-02
Abstract: A pant-type absorbent article 1, having an absorbent assembly 3 comprising an absorbent core and a chassis, the chassis comprising a front portion and a back portion, wherein the front and back portions 5 6 are joined to each other along two opposite longitudinal side edges to define a waist-opening and a pair of leg-openings, at least one of the front and back portions 5 6 comprises an elastic web material 10, the article 1 further comprising a crotch portion located between the front portion 5 and the back portion 6 in the longitudinal direction of the article 1, the front portion 5 having a length in the longitudinal direction, the back portion 6 having a length in the longitudinal direction, and the crotch portion having a length in the longitudinal direction, the absorbent assembly 3 lying at least in the crotch portion and overlapping a certain distance with both the front and back portions 5 6, the article 1 having a longitudinal and a transverse direction, wherein the absorbent assembly 3 overlaps no more than 20% of the surface area of each of the front and back portions 5 6, as measured in an extended state of the article 1.
Patent NZ-556620-A (NZ)
Title: Mechanically operated nail advancement systems for nail arrays disposed within nailing tool magazines
Inventor: PORTH CHRIS H
IPC: B25C1/00
Filed: 2006-02-15
Abstract: A fastener advancement system for example advancing the nail in the magazine of a nail gun using electromechanically operated mechanism is disclosed. The system comprises a driving means consisting of multi-lever and linkage (136) that are operatively connected to the blade member (126) of the fastener driving tool for advancing a leading fastener of a collated strip of fasteners into the driver blade channel of the fastener-driving tool. The system is characterised by the means for separating the leading fastener of the collated strip of fasteners that is movable in response to the rearward movement of the driving means. The system uses push type; pull type and rotary solenoid actuating members for moving the fastener-advancement feed pawl or claw member. Since the system is electromechanically operated it eliminates the need of any exhaust gases that would otherwise be required in the combustion powered fastener advancement system.
Patent NZ-561212-A (NZ)
Title: A method for removing fluoride from alumina comprising washing with aqueous acid or alkali at evevated temperatures
Inventor: OSBORN NIGEL JOHN
IPC: B01J20/08
Filed: 2006-03-21
Abstract: Disclosed is a method for removal of [18F]fluoride from alumina by washing the alumina with an aqueous acid or alkali at a temperature of between 40°C and boiling point of the aqueous acid or alkali. This method may be performed on an automated synthesis apparatus for synthesis of a [18F]radiofluorinated radiotracer.
Patent NZ-566876-A (NZ)
Title: Derivatives of 2-aminthiazoles and 2-aminooxazoles, processes for their preparation and their use as pharmaceuticals
Inventor: KEIL STEFANIE
IPC: A61K31/421
Filed: 2006-09-26
Abstract: Disclosed are 2-phenyl-[1,2,4]oxadiazol-5-one derivatives as represented by formula I, wherein R1, R2, R3 and R4 are independently selected from the group consisting of H, halogen, alkyl, alkylene-O-alkylene-H, SCH3, and CN, wherein the alkyl and alkylene groups are unsubstituted or mono, di- or tri-substituted by F; X is -CH2- or -CH-2-CH2-; U is S or O; and wherein the remaining substituents are as defined herein. Also disclosed is the use of the compounds as defined above for the preparation of a medicament of the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders.
Patent NZ-566916-A (NZ)
Title: Moisture resistant foldable material and container erected from blank
Inventor: GANZENMULLER GEORGE
IPC: B65D5/56
Filed: 2006-09-22
Abstract: A foldable laminated sheet (20) comprises at least one inner polymer layer (23), at least three inner layers of sized paper (21, 24) and an outer polymer layer (25) on each side of the sheet (20). Adjacent layers of paper are glued to each other with an adhesive (22).
Patent NZ-569734-A (NZ)
Title: Holder, electrical supply, and RF transmitter unit for electronic devices
Inventor: NEU THORBEN
IPC: H01R33/945
Filed: 2008-07-10
Abstract: An electronic accessory for coupling two or more electronic devices to an external power supply, and a method of coupling an electronic accessory to an electronic device, is disclosed. The electronic accessory comprises a holder, where the holder includes a cradle section, two or more side supports removably coupled to the cradle section, two or more spacer pads coupled to the cradle section, and a power unit. The cradle section, having a power coupling, is configured to couple to at least two electronic devices where the side supports and spacer pads provide support to the first and second electronic devices when coupled to the cradle section.
Patent NZ-572660-A (NZ)
Title: Novel piperazine compound, and use thereof as HCV polymerase inhibitor
Inventor: ABE HIROYUKI
IPC: A61K31/495
Filed: 2007-04-18
Abstract: Disclosed is a piperazine sulfonyl derivative of formula [I-D1], or a salt thereof, wherein n is 1-3, B1 is an optionally substituted phenyl, C2 is an optionally substituted heterocycle, A is an optionally substituted ring as described herein, and the optional substituents are as defined in the specification. Also disclosed is the use of the compounds for treating hepatitis C virus (HCV).
Patent NZ-573377-A (NZ)
Title: Anti-viral pyrimidine nucleoside derivatives
Inventor: MCGUIGAN CHRISTOPHER
IPC: A61K31/70
Filed: 2007-05-09
Abstract: Disclosed is a compound of general formula (II): wherein X is O, S, NH or CH2, Y is O, S or NH, Z is O, S or CH2, R1 is alkyl, and one of R2 and R3 is H, and the other of R3 and R2 is a neutral, non-polar amino acid moiety, or a pharmaceutically acceptable salt or hydrate thereof. Also disclosed is a method to prepare said compound, the use of the compound to treat viral infections and a composition comprising said compound.
Patent NZ-575932-A (NZ)
Title: A plastic lid for an open topped container with a frangible locking ring
Inventor: RETIEF CHARLES THOMAS
IPC: B29C45/44
Filed: 2007-08-28
Abstract: A plastic lid (1 ) is provided for an open topped generally circular container (2) of the type having an outwardly directed lip (3) encircling the operatively upper open end of the container. The lid comprises a rim (6) of generally annular shape to cooperate with the outwardly directed lip of the container and a squat generally cylindrical section (9) extending from the inner periphery of the rim to a closure wall (10) at its operatively inner end to form a plug type of closure adapted to form a seal with the inner periphery (5) of a cooperant container. The lid has at least one locking member (12) that is preferably an endless locking ring connected to the rim by way of one or more, and preferably multiple, integral frangible connecting elements (14). The locking member is adapted to operatively cooperate with the lip of a cooperant container such that fracturing of one or more of said integral frangible connecting elements occurs during removal or attempted removal of the lid from the container. A mould assembly and process for making the lid are also described.