baber/WOPTO huggingface dataset:
Patent WO-2020053812-A1 (WO)
Title: Alkynyl nicotinamide compounds as kinase inhibitors
Inventor: SINTIM HERMAN O
IPC: C07D471/04
Filed: 2019-09-12
Abstract: This invention relates to Alkynyl Nicotinamide compounds and their derivatives as kinase inhibitors. In addition, uses thereof for treatment of disease such as cancer and, in particular, acute myeloid leukemia are disclosed.
Patent WO-2020065442-A1 (WO)
Inventor: HATSUMI RYO
IPC: H04N5/232
Filed: 2019-09-17
Abstract: One objective of the present invention is to simplify the structure of an imaging device. Provided is an imaging device or an image processing method capable of capturing images without using a lens. Another objective of the present invention is to sharpen defocused image data. Provided is an image processing method for image data in which a plurality of pixels are arrayed. Two adjacently arranged pixels are each divided into a first area and a second area differing from the first area, both areas representing the same pixel value; the second area of the pixel located at the endmost position in the image data is given an initial value; and the pixel values of the first areas and the second areas of the plurality of arrayed pixels are determined sequentially and inductively on the basis of the initial value.
Patent WO-2020079670-A1 (WO)
Title: Woodstove with combustion chamber
Inventor: LÓPEZ LÓPEZ LINA MARÍA
IPC: F24B1/00
Filed: 2019-10-18
Abstract: The present invention relates to a modular stove that increases combustion efficiency when cooking with wood or coal in rural environments where there is no access to electricity or gas and, consequently, it is not possible to cook food using electric grills, microwave ovens or gas stoves. In particular, the invention relates to a stove that is easy to assemble and maintain, with a combustion chamber that provides high thermal efficiency, ensuring fuller wood combustion, thereby reducing the amount of fuel needed to reach high temperatures. The invention also has different extensions that allow the stove to be adjusted to different needs.
Patent WO-2020201960-A1 (WO)
Title: A process for making a continuous layer of at least a metallic foil of the family group of malleable/ductile metallic materials and an apparatus to carry out the process.
Inventor: TRANI GIORGIO
IPC: B32B38/00
Filed: 2020-03-27
Abstract: Procedure for making a continuous tape of at least one metallic material of the family of malleable/ductile metallic materials, described in that a continuous strip (1) of said metallic material is passed between a rigid cylinder (3) and a presser (2) in elastically compressible material, held adherent to said rigid cylinder and at the same time subjecting said continuous belt, in at least a portion of its passage between said rigid roller and said presser and a reduction in the speed of its surface in contact with said presser (21) with respect to the speed of its surface in contact with said rigid cylinder (3) the surfaces of the outgoing tape being always parallel to each other and the final width of the tape corresponding to the initial width.
Patent WO-2020208544-A1 (WO)
Title: Meat analogues and meat analogue extrusion devices and methods
Inventor: PIBAROT PATRICK
IPC: A23L13/60
Filed: 2020-04-08
Abstract: A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include an animal protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including an animal protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the animal protein when the fat or the fat analogue and the material exit the die.
Patent WO-2020212864-A1 (WO)
Title: Use of fulvestrant for the therapeutic management of core myopathy
Inventor: MARTY ISABELLE
IPC: A61P21/00
Filed: 2020-04-15
Abstract: The invention concerns an oestrogen receptor antagonist of formula: for use in the treatment of a disease or disorder linked to a decrease in calcium release between the sarcoplasmic reticulum and the cytosol, in particular the disease or disorder is a myopathy linked to one or more mutations of the gene RyR1 or a myopathy linked to a decrease in calcium release, and more particularly core myopathy. The invention also relates to a pharmaceutical composition comprising at least the oestrogen receptor antagonist of the invention and at least one pharmaceutically acceptable excipient.
Patent WO-2021123934-A1 (WO)
Title: Phosphate de cyclocréatine : nouvelle thérapie bioénergétique pour prévenir et traiter des maladies cardiovasculaires et neurodégénératives induites par ischémie et liées au vieillissement
Inventor: ELGEBALY SALWA A
IPC: C07D233/46
Filed: 2020-09-24
Abstract: La présente invention concerne des procédés et une composition d'un nouveau mécanisme utilisant le phosphate de cyclocréatine bioénergétique en tant que médicament cardioprotecteur puissant par conservation d'une source d'énergie cellulaire, la prévention d'une lésion ischémique, le rajeunissement de la fonction d'organes, et le maintien, par conséquent d'une activité physique normale. Le phosphate de cyclocréatine peut être utilisé en tant que nouvelle approche thérapeutique pour prévenir le développement et la progression d'une maladie, et pour traiter des maladies induites par une ischémie chez des patients souffrant d'une cardiopathie ischémique, y compris : une coronaropathie, une angine instable, un infarctus aigu du myocarde, une insuffisance cardiaque, une fibrillation auriculaire et une cardiomyopathie de Takotsubo, ainsi qu'une cardioprotection pendant des interventions et des chirurgies cardiaques. L'invention concerne en outre des méthodes et une composition pour prévenir et traiter des maladies neurodégénératives liées au vieillissement, l'hypoxie/l'ischémie jouant un rôle clé dans le développement et la progression de la maladie. Plus particulièrement, la présente invention concerne du phosphate de cyclocréatine en tant que nouvelle approche thérapeutique pour prévenir le développement et la progression d'une maladie, ainsi que pour traiter des patients atteints d'ischémie cérébrale (accident vasculaire cérébral) et de la maladie d'Alzheimer.
Patent WO-2021161092-A1 (WO)
Title: Assisting and automating workflows using structured log events
Inventor: SOFER ODED
IPC: G06Q10/00
Filed: 2020-12-30
Abstract: An example system includes a processor to monitor a user interface to generate activity logs including step-flows. The processor is to extract features and common variables from unstructured data in the activity logs and generate structured log events based on the extracted features and the common variables. The processor is to generate a workflow model based on the structured log events. The processor is to automate or assist workflow based on the generated workflow model.
Patent WO-2021140441-A1 (WO)
Title: Head size adaptation mechanism for an eeg net
Inventor: GLEICH BERNHARD
IPC: A61B5/291
Filed: 2021-01-06
Abstract: An electroencephalography net (44) comprised of electrodes (34, 36) coupled together by a connector (28) comprising separate elastically (32) and plastically (30) deformable elements.
Patent WO-2021156696-A1 (WO)
Title: An anchor chair
Inventor: DESCAMPS Rik
IPC: E02D5/80
Filed: 2021-01-23
Abstract: An anchor chair (10) is described comprising two or more passages (112, 114) for an elongated foundation element (20), wherein the passages (112, 114) extend between two or more corresponding openings (122, 124) located on the first side (12) and only one common cavity (140) located on the second opposite side (14). The passage angles (127, 129) of the respective central longitudinal axis (117, 119) of the different passages (112, 114) and/or the abutment angles (133, 135) of the abutment surfaces (132, 134) at the height of the openings (122, 124) of the different passages (112, 114) are different.
Patent WO-2021156729-A1 (WO)
Title: Dynamically modifying shared location information
Inventor: SCHNEIDER SCOTT
IPC: G06F21/60
Filed: 2021-02-01
Abstract: Described are techniques for modifying a shareable location in shared posts. The techniques including a method comprising inputting a social networking post received from a user device to a location precision model executing as an application on the user device, and where the social networking post is associated with a first time and a shareable location. The method further comprises outputting, by the location precision model, a modified shareable location. The method further comprises transmitting the social networking post to a social networking system with a modified shareable location, wherein the modified shareable location is a generalized version of the shareable location.
Patent WO-2021214727-A1 (WO)
Inventor: LISANTI MICHAEL P
IPC: C12Q1/6886
Filed: 2021-04-23
Abstract: Cancer stem cells are responsible for tumor recurrence, distant metastasis and drug-resistance, in the vast majority of cancer patients. There exists an urgent need to identify new mitochondrial inhibitor drugs that can target and eradicate CSCs, and companion diagnostics to identify candidates for mitochondrial inhibition therapy. In 3D mammospheres, 25 mitochondrial-related proteins were over 100-fold over-expressed in a large collection of transcriptional profiling data from ER(+) breast cancer patients. These 25 proteins may be used to derive short gene signatures to predict the likelihood of distant metastasis and tumor recurrence. For example, the 4-gene signature of ACLY, VDAC3, HADH2, and COX6B1 may be used for predicting the likelihood of distant metastasis, with a hazard ratio of 1.91-fold (P=2.2e-08). A pharmaceutically effective amount of a mitochondrial inhibitor may be administered to a candidate having elevated expression of the genes in a gene signature. Five example mitochondrial inhibitors showed preferential and selective inhibition of tumor cell metastasis, without causing significant toxicity. Mechanistically, all five mitochondrial inhibitors have been previously shown to induce ATP-depletion in cancer cells. Gene signatures composed of 6-9 large mitochondrial ribosomal proteins also show prognostic value in predicting distant metastasis, tumor recurrence, and Tamoxifen resistance, in both ER(+) and ER(-) breast cancer patients. The disclosed gene signatures may be used as companion diagnostics to assess which patients may benefit most from mitochondrial inhibition therapy.
Patent WO-2021234550-A1 (WO)
Title: Novel nucleolin-binding peptide and use thereof
Inventor: KIM JAEIL
IPC: A61K47/60
Filed: 2021-05-18
Abstract: The present invention relates to a novel peptide that specifically binds to nucleolin and, more specifically, to a peptide represented by a specific amino acid sequence, a conjugate comprising the peptide and an anticancer drug, a fusion peptide comprising the peptide and a cell-penetrating peptide, a composition for diagnosing cancer comprising the peptide, and a composition for preventing or treating cancer comprising the peptide or the conjugate. In the present invention, it has been confirmed that a peptide ligand AGM peptide and mutants thereof, as screened using an MAP synthesis method and an OBOC combination method, specifically bind to cancer cells, and a conjugate thereof with an anticancer drug inhibits cancer growth (in vitro and in vivo). Thus, the NCL-targeting AGM peptide can be effectively used for diagnosis and targeted drug delivery in cancer therapy.
Patent WO-2021234680-A1 (WO)
Title: System for integration into a fruit processing facility
Inventor: STRACHAN GARY
IPC: C12G1/02
Filed: 2021-05-25
Abstract: The system comprises one or more transportable bioreactors configured with the ability to conduct aerobic fermentation of fruit biomass. This system integrates three functionalities: transportation regulations, fermentation requirements and food safety/quality control requirements. The transportation design features of the system render the bioreactors transportable to a fruit processing facility, wherein they can be filled with fruit biomass. The transportable bioreactor and processes take into account the requirements of the bioreactor functionalities of the system, given the particular deployment specifications of the system tailored for a certain environment and fruit biomass. Moreover, the design of this system conforms to the minimal requirements for the food safety and quality regulations of the jurisdictions in which the ultimate products will be directly and/or indirectly sold (e.g., as a foodstuff, health supplement, and/or a food ingredient). The integration of these three types of functionalities (transport, bioreactor and sanitation) gives rise to a practical solution for addressing the various problems of wasted foodstuffs such as fruit biomass.
Patent WO-2022013637-A1 (WO)
Title: Seat cover for motorcycles equipped with multifunction electronic unit
Inventor: MARESCA VINCENZO
IPC: B62J6/05
Filed: 2021-06-04
Abstract: Device comprising a seat cover (1) which can be fastened to the seat of a motorcycle (13), whose upper surface is divided in a plurality of portions each positioned on the right side or left side of said seat cover (1), each one of which being associated to a respective vibration motor, configured to generate vibrations perceivable by the motorcyclist while seating on the seat of said motorcycle (13), electronic computing means (7) configured to control said vibration motors and provided with connecting means to the onboard electronic box (14) of said motorcycle (13), characterized in that said electronic unit (7) is configured to receive from said onboard box (14) of said motorcycle (13) a signal relating to the activation status of the directional indicators (19) of said motorcycle (13) and to control said vibration motors (2, 3, 4, 5) as a function of said signal relating to the activation status of said directional indicators.
Patent WO-2022009025-A1 (WO)
Inventor: OGITA KAORI
IPC: C07D233/58
Filed: 2021-06-30
Abstract: La présente invention concerne un solvant non aqueux qui a une grande résistance à la chaleur et peut être utilisé dans une large plage de températures ; une batterie rechargeable ; et un véhicule. Un solvant non aqueux selon la présente invention comprend un carbonate cyclique fluoré et de 50 % en volume à 95 % en volume d'un liquide ionique, le liquide ionique contenant des cations imidazolium. Comme ce solvant non aqueux de la présente invention a une viscosité qui est supprimée aux basses températures, tout en ayant une grande résistance à la chaleur, ce solvant non aqueux peut être utilisé sur une large plage de températures.
Patent WO-2022003583-A1 (WO)
Title: Aminopyrimidinyl derivatives
Inventor: GERSTENBERGER BRIAN STEPHEN
IPC: A61K31/4995
Filed: 2021-06-30
Abstract: A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein R 1  and R 2  are each independently hydrogen or hydroxy; wherein R 1  and R 2  are not both hydroxy. Also provided are methods of treatment as Janus Kinase inhibitors and pharmaceutical compositions containing the compounds of the invention and combinations thereof with other therapeutic agents.
Patent WO-2022185113-A1 (WO)
Inventor: MICHNA STEFAN
IPC: C04B12/00
Filed: 2021-08-20
Abstract: The invention relates to the geopolymer suspension for insoluble heat- and corrosion-resistant coatings for the surfaces of Fe alloy products that contains 20 to 25% wt. of the aqueous solution of 80% to 90% wt. phosphoric acid, 25 to 30% wt. of aluminosilicate, 4.6 to 5.2% wt. of graphite, and the remainder is isopropyl alcohol. It further relates to the method of preparing the geopolymer suspension, wherein 20 to 25% wt. of the aqueous solution of 80 to 90% phosphoric acid is added to 100 ml of isopropyl alcohol and 25 to 30 g of kaolin is gradually added while stirring at laboratory temperature for 8 to 15 minutes. After 9 to 15 minutes, 4.6 to 5.2 g of graphite as an additive is added at once, and the resulting mixture is homogenised for another 18 to 25 minutes.
Patent WO-2022058947-A1 (WO)
Inventor: SINCLAIR ALEXANDRA
IPC: A61K38/22
Filed: 2021-09-17
Abstract: La présente invention concerne une méthode de réduction de la pression intraoculaire. La présente invention concerne en particulier une méthode de réduction de la pression intraoculaire chez un sujet pour traiter un trouble associé à la pression intraoculaire, la méthode consistant à administrer au sujet un agoniste du récepteur du GLP-1 ou un sel pharmaceutiquement acceptable de celui-ci.
Patent WO-2022058986-A1 (WO)
Title: A grading and sorting conveyor system for agricultural products
Inventor: PHUTANE PRAVIN CHANDRAKANT
IPC: B07C5/00
Filed: 2021-09-21
Abstract: The present disclosure relates to storage facilities for agricultural products and envisages a grading and sorting conveyor system (100) offering an enhanced ability in segregation of products. The system (100) comprises a grading means (10) having a plurality of graders aligned consecutively to each other. Each grader is defined by a flat frame extending into an inclined frame, and a meshed screening belt provided on each frame for receiving the agricultural products thereon. The meshes of the consecutive graders have successively increased dimensions to allow a product having dimensions corresponding to dimensions of the meshes to drop therethrough. A sorting means (20) is disposed beneath each grader for receiving the product falling through the meshes to facilitate manual sorting of the product.
Patent WO-2022101710-A1 (WO)
Title: Mesures oculaires biométriques à l'aide d'un apprentissage profond
Inventor: ANGELOPOULOS ROBERT DIMITRI
IPC: G06V40/19
Filed: 2021-10-14
Abstract: L'invention concerne un procédé d'estimation de mesures dimensionnelles de points de repère biométriques d'un œil humain, ledit procédé consistant, dans un mode de réalisation possible, à recevoir une ou plusieurs images de l'œil humain par l'intermédiaire d'un ordinateur hôte. En réponse à la réception de la ou des images, le procédé consiste à générer un ensemble préliminaire d'emplacements de points de repère dans la ou les images par l'intermédiaire de l'ordinateur hôte à l'aide d'un algorithme d'apprentissage profond, puis à affiner l'ensemble préliminaire d'emplacements de points de repère à l'aide d'une routine de traitement post-hoc de l'ordinateur hôte afin de générer ainsi un ensemble final d'emplacements des points de repère estimés. De plus, les mesures dimensionnelles de points de repère biométriques sont automatiquement générées par l'intermédiaire de l'ordinateur hôte à l'aide de l'ensemble final d'emplacements des points de repère estimés. Un ensemble de données est ensuite sorti, ce dernier englobant l'ensemble d'emplacements de points de repère estimés. Un ordinateur hôte exécute des instructions provenant de la mémoire pour appliquer le procédé.
Patent WO-2022144828-A1 (WO)
Inventor: JAKUBOVITZ BAR
IPC: G06F16/28
Filed: 2021-12-30
Abstract: L'invention concerne un procédé, comprenant l'accès à une base de données source (34) comprenant des enregistrements (70) dans des tables (36), qui sont organisées en une hiérarchie définissant des tables parentes (86) et dépendantes (88) respectives, contenant des enregistrements parents (82) et dépendants (84) respectifs, les enregistrements comprenant des valeurs (74). Lors de la présentation d'une première liste (140) des tables, une entrée est reçue, laquelle sélectionne une table. Lors de la présentation d'une seconde liste des tables associées à la première table, une entrée est reçue, laquelle sélectionne une autre table dans la seconde liste. Lors de la présentation de critères de filtrage (180) pour les tables sélectionnées, une demande de filtrage est reçue pour une table sélectionnée donnée. La demande est appliquée à la table donnée pour sélectionner un sous-ensemble des enregistrements dans la table donnée et pour générer une base de données cible (38) comprenant le sous-ensemble des enregistrements et les enregistrements dans l'ensemble qui sont les enregistrements associés respectifs des enregistrements dans le sous-ensemble.
Patent WO-2022172221-A1 (WO)
Inventor: VAN BELLEGHEM LUKE PIERRE
IPC: G06F16/951
Filed: 2022-02-11
Abstract: Selon un exemple, l'invention concerne un procédé pour améliorer les résultats de recherche destinés à un public cible. Le procédé consiste à recevoir une demande d'origine pour la génération d'un identifiant cible, la demande d'origine comprenant un site web cible et un ensemble d'attributs définissant un public cible du site web cible ; le stockage d'une association entre l'identifiant cible, le site web cible et l'ensemble d'attributs définissant le public cible ; et la fourniture d'un hyperlien menant au site web cible, l'hyperlien codant l'identifiant cible. L'identifiant cible peut être vérifié par un moteur de recherche pour améliorer les résultats de recherche destinés au public cible.
Patent WO-2022229882-A1 (WO)
Inventor: HUANG KO-KAI
IPC: G06V20/52
Filed: 2022-04-27
Abstract: L'invention concerne un dispositif électronique d'estimation de fumée. Le dispositif électronique reçoit une première image d'une pluralité d'images d'un espace physique. Le dispositif électronique détecte la fumée dans l'espace physique sur la base d'une application d'un modèle de réseau neuronal entraîné sur la première image reçue. Le dispositif électronique génère une carte thermique de l'espace physique sur la base de la fumée détectée dans l'espace physique, et en outre sur la base d'une sortie du modèle de réseau neuronal entraîné correspondant à la détection de la fumée. Le dispositif électronique estime un niveau de fumée dans l'espace physique sur la base d'une normalisation de la carte thermique générée.
Patent WO-2023119171-A1 (WO)
Inventor: FALCO DAVIDE
IPC: C12M1/00
Filed: 2022-12-21
Abstract: A cover (1) for bioreactors (2), preferably photobioreactors, is described, wherein the cover (1) is configured to be releasably connected to the tank (3) of the bioreactor (2) containing a bioreactor fluid, preferably a culture liquid. The cover (1) includes sensor means (4), a control unit (5) configured to manage the operation of the bioreactor (2) based on measurement signals provided by said sensor means (4), and lighting means (7) arranged to emit a light radiation on the bioreactor fluid contained in the tank (3).
Patent WO-2023187474-A1 (WO)
Title: Système d'apprentissage à rétroaction asynchrone et à distance
Inventor: VARAS COHEN JULIAN
IPC: G06Q50/20
Filed: 2023-03-30
Abstract: La présente invention est un système qui facilite le transfert de compétences d'un utilisateur à profil d'enseignant à un utilisateur ou à un groupe d'utilisateurs ayant un profil d'étudiant, à distance et de manière asynchrone, permettant à des utilisateurs à profil d'étudiant de recevoir une rétroaction provenant de l'utilisateur à profil d'enseignant. Le système comprend un module étudiant, un module de stockage, un module de commande, un module administrateur et un module enseignant.