baber/WOPTO huggingface dataset:
Patent JP-H0660195-B2 (JP)
IPC: C07J9/00
Filed: 1991-12-25
Abstract: The present disclosure is directed to a process and intermediates for the synthesis of Vitamin D3 metabolites such as 1,25-dihydroxycholecalciferol, 25-hydroxycholecalciferol and 24R,25-dihydroxycholecalciferol from 17-keto steroids via intermediates having the natural steroid configuration at the 20-position. These novel intermediates are prepared from 17-keto steroids by reaction with ethyltriphenylphosphonium halides followed by reaction with formaldehyde to form comounds having the natural steroid configuration at the 20-position and which are suitable substrates for the preparation of the aforementioned Vitamin D3 metabolites.
Patent JP-2843146-B2 (JP)
IPC: A61K31/194
Filed: 1989-10-20
Granted: 1999-01-06
Abstract: Novel methods are provided for treating hypertension in humans which comprise administering therapeutic amounts of pharmaceutically-acceptable non-halide salts of potassium. Preferred salts are potassium bicarbonate and potassium phosphate. The methods may also be used to lower the blood pressure of normotensive individuals. Dietary supplemention is a preferred and convenient method of administration. <IMAGE>
Patent JP-3145111-B2 (JP)
IPC: A61K9/52
Filed: 1990-11-15
Granted: 2001-03-12
Abstract: Described herein are methods comprising the oral administration of budesonide for the treatment of ulcerative colitis and Crohn's colitis in its active phase. The methods can also be applied as relapse preventing therapy for Crohn's colitis in its chronic phase and Crohn's disease in the small intestine.
Patent JP-4014649-B2 (JP)
IPC: F16K17/02
Filed: 1998-05-19
Granted: 2007-11-28
Abstract: A shield for a pressure relief device for containing and deflecting released fluids is described. The shield includes an enclosure for surrounding the pressure relief device, the enclosure having a first port for engaging the enclosure to a relief duct while permitting the shield to be positioned in a necessary orientation on the device.
Patent JP-2946428-B2 (JP)
IPC: B65B69/00
Filed: 1990-12-13
Granted: 1999-09-06
Abstract: A cutting device for a wire removing machine for cutting through tie wires of bales, in particular cellulose bales, has essentially two elongate cutters (5, 6) that can move back and forth in relation to each other, each provided at their cutting edges with a row of regularly spaced teeth (16, 17) having an undercut on their front flanks, in the cutting direction. In order to precisely define the moment when the wires are cut and at the same time ensure that a gripping device has already reliably clamped the tie wires before they are cut through by the cutting device, the front flanks (18, 19) of the teeth (16, 17) have at their lower end, in the area of the tooth root, a receiving pocket (21, 22) for at least one tie wire, the back ends of the receiving pockets (21, 22) forming knife-edges (24). The sections of the front flanks (18, 19) of the teeth (16, 17) that extend between the tip (20) of the tooth and the corresponding receiving pocket (21 or 22) form blunt slide edges.
Patent JP-3309356-B2 (JP)
IPC: A61K49/00
Filed: 1990-12-19
Granted: 2002-07-29
Abstract: The present invention relates to a method for synthesizing a liposome having encapsulated therein a gas comprising contacting the liposomes in the liquid medium with gas under elevated pressure. The liposomes so produced and are useful in ultrasonic imaging techniques. <IMAGE>
Patent JP-2667694-B2 (JP)
IPC: G03B42/04
Filed: 1988-05-09
Granted: 1997-10-27
Abstract: PCT No. PCT/EP88/00403 Sec. 371 Date Nov. 8, 1989 Sec. 102(e) Date Nov. 8, 1989 PCT Filed May 9, 1988 PCT Pub. No. WO88/09002 PCT Pub. Date Nov. 17, 1988.In a device for holding down the lower cassette portion (19a) of an X-ray film cassette which is located in a cassette unloading and reloading apparatus, a hold-down lever (20, 21) is mounted to each of two parallely guided bars (10, 12) movable towards and away from each other respectively, said hold-down lever being pivotable into, and out of the transport path of the X-ray film cassette to accurately position said cassette. Each hold-down lever (20, 21) comprises a control arm (20a, 21a) resting against each of the two side walls (19d, 19e) of the upper cassette portion (19c). Since the control arms (20a, 21a) are upwardly inclined such that they form control surfaces facing the side walls (19d, 19e) of the upper cassette portion (19c), the hold-down levers (20, 21) are held in engagement with the lower cassette portion (19a) when the upper cassette portion (19c) is in its open position and are disengaged from the lower cassette portion (19a) when the upper cassette portion (19c) is in its closed position.
Patent JP-2941420-B2 (JP)
IPC: A23L13/40
Filed: 1990-03-07
Granted: 1999-08-25
Abstract: A method is provided of reconstituting meat products which comprises mixing with a de-boned or separated meat (D or S meat), a fibrous collagen in order to distribute the added collagen substantially homogeneously throughout the D or S meat, removing occluded air and voids from the mixture and forming the mixture into discrete portions or a continuous extrusion by pressing the mixture through a restrictor. Normally between 1 and 10 % of fibrous collagen is incorporated in the reconstituted meat product.
Patent JP-H0761325-B2 (JP)
IPC: A61B5/11
Filed: 1986-07-28
Abstract: PCT No. PCT/AU86/00215 Sec. 371 Date Mar. 30, 1987 Sec. 102(e) Date Mar. 30, 1987 PCT Filed Jul. 28, 1986 PCT Pub. No. WO87/00746 PCT Pub. Date Feb. 12, 1987.A method and apparatus for determining the level of attention of a subject to a visual stimulus such as a television commercial displayed on a screen (4) so as to provide objective information for designing the advertising presentation. The technique involves reflecting visible red radiation from arrays (16) of LEDs towards the eyes of the subjects (2) as a control signal at a predetermined frequency. The control signal is first applied to the subjects and EEG responses obtained. The control signal is then simultaneously applied with the display of the television commercial and EEG signals are again obtained. An assessment of the subjects interest is then made by determining the diminution in value of the components of the EEG response attributable to the control signal. A pair of illuminated goggles is also disclosed.
Patent JP-4374503-B2 (JP)
IPC: G11C7/22
Filed: 1998-06-18
Granted: 2009-12-02
Abstract: A computer system with a memory device having plural memory banks and a method of accessing a selected one of the memory banks, the memory device includes local control signal generators that control timing of operations in each respective block of a memory array. Overall timing of the device is controlled by first and second global control signals generated in a command sequencer and decoder. The second global control signal is derived from a delayed version of the first signal, and both signals are applied to local control signal generators along with address bits indicating a selected block. Local timing is determined by the global control signals and by local circuitry within the local control signal generators.
Patent JP-H047117-B2 (JP)
IPC: C09K3/00
Filed: 1987-09-10
Abstract: A process for selective metallization of a substrate in a predetermined desired pattern, and particularly for the manufacture of printed circuit boards, in which a substrate patterned in desired manner with resist material is treated with conditioning agent, adjuvant and deactivating agent preparatory to catalytic activation and electroless deposit of metal flash. By proceeding in this manner, adherent flash metal deposit is achieved on non-resist areas without encountering significant plating on resist areas. Following metal flash deposit, the resist can be easily and cleanly stripped and additional metal then built up on the flash metal.
Patent JP-2775186-B2 (JP)
IPC: B02B1/08
Filed: 1989-07-13
Granted: 1998-07-16
Abstract: According to the present invention, there is provided a process for par-boiling rice, comprising the steps of:   (a) treating the rice with water at a temperature up to its boiling point to increase its water content to 17 to 28%; (b) steaming the soaked rice at a temperature from 100 to 125 DEG C to increase its water content to 19 to 30%; (c) heating the steamed rice, in a sealed vessel, under pressure and using dry heat, to a minimum temperature of approximately t DEG C, wherein t = 195 - 2.5 M and M is the moisture content of the steamed rice in %, for from 1 to 5 minutes; (d) reducing the pressure on the rice over a period of 1 to 10 minutes to atmospheric pressure, thereby allowing water to evaporate from the heated rice to reduce its temperature to approximately 100 DEG C and its water content to 17 to 24%; and   (e) drying the partially dried rice to microbiological stability.   The product of the present invention has better consumer appeal than conventional par-boiled rice.
Patent JP-3346566-B2 (JP)
IPC: B21D39/03
Filed: 1992-11-25
Granted: 2002-11-18
Abstract: In a clinched joint (11) to secure panels (12, 13) together, a rivet or slug (10) is driven into the clinched joint (11) as it is formed, and the inner end of the rivet or slug (10) is outwardly-deformed to increase both the shear and axial separation load strengths of the clinched joint (11). Rings (410) or components (510, 610), which may form parts of sub-assemblies, may also be secured to the pannels (412, 413; 512, 513; 612, 613) by the clinching methods, the rings (410) or components (510, 610) acting as the dies for the joints (411, 511, 611).
Patent JP-3390432-B2 (JP)
IPC: B65D47/26
Filed: 1992-03-31
Granted: 2003-03-24
Abstract: This invention provides a compact and convenient dental tool container which is particularly useful for storing dental posts, post wrenches and reamers, and stops for reamers, plus a gauge, coordinating several of a dentist's requirements in a helpful way. A handheld circular tool holder has a number of peripheral compartments for the tools and a selector lid rotatable on the tool holder which selector lid has an opening to access the peripheral compartments. Optionally, a secondary compartment and access opening in the lid provide storage for the post wrenches. A novel breakaway tab locks the lid closed for distribution and marketing, and preferably engages in a unique gauge block for sizing the reamers; alternatively an indexing ratchet restricts rotation of the lid. The invention includes a kit comprising the container charged with the several tools described.
Patent JP-3547749-B2 (JP)
IPC: C07C233/14
Filed: 1994-10-20
Granted: 2004-07-28
Abstract: The present invention relates to a novel enantiospecific process for preparing (S)-1-[2(S)-(1,3-dihydro-1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl ]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester which is a useful intermediate in the preparation of [4S-[4 alpha , 7 alpha (R*), 12b beta ]]-7-[(1-oxo-2(S)-thio-3-phenylpropyl) amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo-pyrido[2,1-a][2]benzazepine-4-carboxylic acid and [4S-[4 alpha , 7 alpha (R*), 12b beta ]]-7-[(1-oxo-2(S)-acetylthio-3-phenylpropyl)amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo-pyrido[2,1-a][2]benzazepine-4-carboxylic acid and pharmaceutically acceptable salts thereof which is useful as an inhibitor of enkephali nase and angiotensin converting enzyme and to novel intermediates thereof.
Patent JP-3930564-B2 (JP)
IPC: A61K35/14
Filed: 1996-10-03
Granted: 2007-06-13
Abstract: Patient-specific immune-adsorbers (I) comprise separated antigens and/or antibodies from patients immune complexes from pathologically relevant immune factors bound to activated solid supports.
Patent JP-3522272-B2 (JP)
IPC: D06M16/00
Filed: 1993-04-05
Granted: 2004-04-26
Abstract: Methods for isolating EG III cellulase component and enriched EG III cellulase in polyethylene glycol are disclosed. The methods comprise adding an inorganic salt and polyethylene glycol having a molecular weight of from about 5,000 to 10,000 to an aqueous mixture of cellulase proteins under conditions to create a two-phase system. Next, the cellulase proteins other than EG III are separated in an EG III-poor aqueous phase while EG III cellulase component is retained in an EG III-rich polyethylene glycol phase. Lastly, the EG III component can be separated from the polyethylene glycol. The preferred method of separation is alcohol precipitation.
Patent JP-3420586-B2 (JP)
IPC: A61K48/00
Filed: 1996-11-27
Granted: 2003-06-23
Abstract: The present invention provides a chimeric adenovirus coat protein, which differs from the wild-type coat protein by the introduction of a nonnative amino acid sequence. Such a chimeric adenovirus coat protein according to the invention is able to direct entry into cells of a vector comprising the coat protein that is more efficient than entry into cells of a vector that is identical except for comprising a wild-type adenovirus coat protein rather than the chimeric adenovirus coat protein. The chimeric coat protein preferably is a fiber, hexon, or penton protein. The present invention also provides an adenoviral vector that comprises the chimeric adenovirus coat protein, as well as methods of constructing and using such a vector.
Patent JP-2930421-B2 (JP)
IPC: A61K47/48
Filed: 1995-02-28
Granted: 1999-08-03
Abstract: A novel method of delivering drugs and diagnostics across the blood-brain barrier or blood-nerve barrier is disclosed. Drugs or diagnostic agents are incorporated into nanoparticles which have been fabricated in conventional ways. These nanoparticles are then coated with additional surfactant and given to the body of animals or humans. This allows drugs or diagnostic agents to cross the blood-brain barrier (bbb) to achieve one or more of the following benefits: (1) reducing the dose of a therapeutic drug or diagnostic agent which, when given peripherally, maintains the biological or diagnostic potency in the nervous system, (2) allowing drugs that normally do not cross the bbb to penetrate into the nervous system, and (3) reducing the peripheral side effects by increasing the relative amount of the drug reaching the brain.
Patent JP-3920346-B2 (JP)
IPC: E21B10/38
Filed: 1997-02-20
Granted: 2007-05-30
Abstract: A drill bit for percussive drilling includes a front surface in which cutting inserts are mounted. A recess is formed in the front surface, and a fluid channel extends through the drill bit for supplying flushing fluid to the recess. The recess is completely bordered by an endless land. Some of the cutting inserts are mounted in the land. Others of the cutting inserts are mounted in the recess in order to be cooled and flushed by a cushion of flushing fluid created in the recess.
Patent JP-4290766-B2 (JP)
IPC: A61K31/00
Filed: 1998-01-21
Granted: 2009-07-08
Abstract: The invention relates to a polysaccharide-peptide conjugate wherein the polysaccharide is advantageously immunogenic, which comprises a polysaccharide chain composed of repeat units and a plurality of peptide moieties, each moiety containing a cysteine residue and being covalently attached at random along the polysaccharide chain, through an indirect bond being achieved through either a linker or a spacer-linker moiety provided that the spacer entity of the spacer-linker moiety is linked to the amino, hydroxyl or carboxyl group of the polysaccharide. To this end a useful linker may be, e.g., N-(gamma-maleimidobutyrloxy)succinimide ester. Such a conjugate may typically exhibit a "Rake" configuration. Conjugation processes are also disclosed. Conjugates of the invention are in particular useful in the vaccinal field to elicit a protective long term immune response against a pathogenic microorganism from which the Immunogenic polysaccharide is derived.
Patent JP-3501464-B2 (JP)
IPC: H04L12/56
Filed: 1998-01-19
Granted: 2004-03-02
Abstract: The invention relates to a cellular packet radio network and to a method for updating a routing area in a packet radio network. Packet radio support nodes (SGSN) are connected to a digital cellular radio network (BSS), which provides a radio interface for the support nodes for packet-switched data transmission between the support nodes and mobile stations. There is a logical link between a mobile station (MS) and a serving packet radio support node (SGSN). The packet radio network utilized logical routing areas, each of which comprises one or more cell. Each cell broadcasts information on the routing area to which it belongs. The mobile station sends a routing area update request to the packet radio network when it roams to a new cell which belongs to a different routing area than the old cell. The update request includes the identifiers of the old and new routing area. When the packet radio node detects a routing area update carried out by an unknown mobile station, it initiates the establishment of a logical link by sending a link establishment message (LLC Subm, 21, 21') to the mobile station, the message including the same identifier the mobile used for itself in the routing area update request. The mobile station initializes the logical link at its own end and sends and acknowledgement to the serving packet radio support node.
Patent JP-4226649-B2 (JP)
IPC: A61K38/00
Filed: 1996-05-15
Granted: 2009-02-18
Abstract: The present invention relates to a method for forming microparticles of a material from microdroplets of a solution, wherein the solution comprises the material dissolved in a solvent. The method includes the steps of directing the microdroplets into a freezing zone, wherein the freezing zone is surrounded by a liquified gas, and wherein the microdroplets freeze. The frozen microdroplets are then mixed with a liquid non-solvent, whereby the solvent is extracted into the non-solvent, thereby forming the microparticles.
Patent JP-3197280-B2 (JP)
IPC: G01N33/569
Filed: 1997-05-27
Granted: 2001-08-13
Abstract: Methods for determining levels of endotoxin in a sample are provided. These methods are useful in the diagnosis of septicemia. Kits for the detection of endotoxin are also provided.
Patent ES-2170035-B2 (ES)
Title: Dispositivo de control de autoestrangulador.
Inventor: WAKAYAMA HIROFUMI
IPC: F02M1/12
Filed: 2001-03-05
Granted: 2006-07-16
Abstract: Dispositivo de control de autoestrangulador. Problema: Mejorar la exactitud de control de un autoestrangulador sin mayores costos. Medios para resolver el problema: Cuando la velocidad del motor detectada por el sensor detector de velocidad 49 es igual o mayor que una velocidad establecida, usando el microordenador 46, el tiempo que se suministra corriente al calentador de autoestrangulador de tipo PTC 42 se controla por control de impulso del transistor 47, y así no hay que utilizar la resistencia externa de la técnica relacionada para regular el voltaje a un calentador de autoestrangulador. Además, cuando tal autoestrangulador se aplica a motores con características diferentes, el cambio de la anchura del impulso de activación del microordenador 46 según las características correspondientes de los motores puede tratar fácilmente tales diferencias.
Patent ES-2201940-B2 (ES)
Title: Sistema acidulante para marinadas.
Inventor: FORMANEK JOSEPH A
IPC: A23L27/10
Filed: 2001-09-14
Granted: 2005-01-01
Abstract: Sistema acidulante para marinadas. 
     Un sistema acidulante para marinadas para carne y
pescado, que comprende  citrato de sodio y ácido cítrico en
intervalos especificados.
Patent ES-2397874-B2 (ES)
Title: Líneas celulares y su uso para la identificación de fármacos para el carcinoma tiroideo.
Inventor: BRAVO LOPEZ SUSANA BELEN
IPC: A61K48/00
Filed: 2010-09-03
Granted: 2013-09-27
Abstract: Líneas celulares y su uso para la identificación de fármacos para el carcinoma tiroideo.#La presente invención se refiere al uso un sistema de líneas celulares de carcinoma tiroideo modificadas para expresar p27Kip1 exógeno en niveles estables o niveles inferiores de TNIP2 respecto de los niveles control, y al animal no humano que comprende dichas líneas. Además, la presente invención se refiere al uso de dichas líneas y dicho animal para el cribado de fármacos para el carcinoma tiroideo, así como a un kit que comprende dichas líneas.
Patent ES-2416930-B2 (ES)
Title: Tobera de inyección para la mejora aerodinámica en vehículos
Inventor: GARCIA RUBIO ANTONIO
IPC: B62D35/00
Filed: 2011-12-30
Granted: 2014-04-10
Abstract: Tobera de inyección para la mejora aerodinámica en vehículos.#Tobera de inyección para la mejora aerodinámica de vehículos, en particular motocicletas, que comprende un cuerpo principal alargado de forma curvada y sección variable, con una boca de entrada de aire en un primer extremo, para la recogida del flujo de aire incidente y, una boca de salida en un segundo extremo, para la salida del mismo.#El aire recogido por la boca de entrada es conducido a contracorriente por el cuerpo principal hasta la boca de salida, modificando el perfil aerodinámico del vehículo. El cuerpo principal puede comprender medios que eviten el desprendimiento de la capa límite y medios que aumentan la velocidad de salida del flujo de aire.
Patent IE-S86147-B2 (IE)
Title: A module to generate electricity from water waves
Inventor: TIMMONS BRIGID
IPC: F03B13/00
Filed: 2012-06-19
Abstract: A module to generate electricity from water waves. The present invention relates to an electricity generating module. In particular the invention has a square base footprint measuring 30 metres by 30 metres with a side elevation of 3 metres high on all sides. It is made of standard range shipbuilding grade steel plate. The structure is anchored to the ground beneath the water. The said structure is a steel box fabrication filled with air-in which a moving water-weighted weight rotates on a central shaft which drives a hydraulic pump. The module utilizes the energy produced by waves of longer lengths: 50-100 metres. The advantage of the module is that no fossil fuels are used as the total energy produced results from the constant and predictable supply of wave motion. There are no carbon dioxide emissions from the device. The module’s optimum environment is ideally in 40-60 metres depth of water, 5-10 kilometres from the shore accessing large wave swells. Inside the module a centre shaft continuously rotates due to constant wave motion. The hydraulic pump is connected to hydraulic drives which turn the generators.
Patent AU-2001286977-B2 (AU)
Title: Ophthalmic surgical system and method
Inventor: DYBBS ALEXANDER
IPC: A61F9/013
Filed: 2001-09-01
Granted: 2005-07-21
Abstract: A system (20) for ophthalmic surgery includes a control assembly (24) placed away from the patient to prevent contamination, and a sterile disposable microkeratome (22) for performing surgery on a patient's eye. The disposable microkeratome is connected to the reusable control assembly by a cable (28). The microkeratome includes a base that sits on the eye, and a carriage that supports and guides a cutting blade as it moves relative to the base. The base includes a main portion that holds the microkeratome on the eye and a handle that extends away from the main portion. The cable is connected to the microkeratome at an end of the handle spaced from the main portion to help maintain the sterility of that portion of the microkeratome.
Patent AU-2002219057-B2 (AU)
Title: Edible spread containing a natural fat phase
Inventor: OOSTEN CORNELIS WILLEM VAN
IPC: A23D7/04
Filed: 2001-10-22
Granted: 2006-06-01
Abstract: Edible W/O emulsion spread comprising a continuous fat phase which contains a natural structuring hardstock fat, which hardstock fat contains at least 45 wt. % of SOS triglyceride (S is C18-C24 fatty acid residue and 0 is an oleic acid residue). A fat with such composition may be isolated from plants belonging to the genus Allanblackia or the genus Pentadesma.