baber/WOPTO huggingface dataset:
Patent CA-2843587-A1 (CA)
Title: Microfluidic drug delivery devices
Inventor: ANAND PJ
IPC: A61M25/01
Filed: 2012-08-01
Abstract: The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.
Patent CA-2844271-A1 (CA)
Title: Multi-pass flue-type water heater
Inventor: GORDON MICHAEL
IPC: F24H1/20
Filed: 2003-06-03
Abstract: Improving heat exchange efficiency in a water heater is difficult and there may be effects of water condensation associated with such efficiency. Components of a water heater are provided to facilitate efficient water heating and to address the effects of water condensation.  The components of the water heater include a water tank, flue segments, a collector assembly for directing products of combustion between the flue segments, an insulator at least partially defining a chamber configured to direct products of combustion between the flue segments, and a cover that at least partially surrounds the insulator. The insulator, in an uncompressed state, may be dimensioned to extend outwardly from the cover when the insulator is positioned in the cover. In a compressed state, the insulator is dimensioned to permit contact between the cover and the water tank to, for example, facilitate forming a seal.
Patent CA-2844658-A1 (CA)
Inventor: MCGINNIS ROBERT
IPC: B01D61/36
Filed: 2012-08-08
Abstract: The invention relates to membrane modules and applications therefor. In particular, the invention relates to the construction of membrane modules for use in forward osmosis, heat exchange, and distillation processes.
Patent CA-2846962-A1 (CA)
Title: Threshold
Inventor: KARL JEFFREY G
IPC: E06B1/70
Filed: 2014-03-17
Abstract: A threshold system and threshold insert for transitions through doorways. An insert for a threshold saddle to be used with a door includes an elongated member for providing a seal along a bottom edge of the door and to be received in a seat in the saddle. The insert defines a door engagement surface adapted to extend across both the seat and the change in elevation to engage the door to provide the seal. When installed for use, the door engagement surface, the saddle adjacent to the sides of the seat, or both provide an overall slope of at least or approximately 2 units horizontal to 1 unit vertical. A threshold system includes a saddle and the insert. The door or an appurtenant door shoe may have an angled surface to interface with the door engagement surface of the insert.
Patent CA-2847857-A1 (CA)
Inventor: LINDERMAN JUSTIN
IPC: A61F2/38
Filed: 2012-08-15
Abstract: Disclosed herein are methods, compositions and tools for repairing an articular joint having a failed implant. The articular repair systems are customizable or highly selectable by or adaptable to individual patients and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by or adaptable to individual patients to increase the speed, accuracy and simplicity of performing total or partial arthroplasty including revision surgeries.
Patent CA-2851224-A1 (CA)
Inventor: HALLGREN INGVAR
IPC: B01D27/08
Filed: 2012-10-05
Abstract: A dust collector (90) is presented that includes an outer wall structure (1a);an inner wall structure (8a) that is within the outer wall structure (1a);a swirl generator (9), in an operating configuration, configured to induce an outer cyclone movement (20) between the outer wall structure (1a) and the inner wall structure (8a). The swirl generator (9), in the operating configuration, can be further configured to induce an inner cyclone movement (22) inside the inner wall structure. Additionally, a filter unit (200) is presented that includes an outlet (204) fluidly coupled to the inlet (202), and a filter media (206) configured to divide a flow path into a clean portion (234) and a contaminated portion (232), such that the fluid flows from the inlet (202) and through the filter media (206) before exiting the filter (200) through the outlet (204).
Patent CA-2858678-A1 (CA)
Inventor: WEITENDORF NIELS
IPC: H02M5/42
Filed: 2014-08-07
Abstract: There is disclosed a method and device for operating an N-level K-phase electrical power converter (200) where N is greater than or equal to 3 and K is greater than or equal to 1.                                                                 A plurality of N connection points (A1, ..., A3) are provided that each correspond to a definable potential. A  first connection point (A1) corresponds to a first potential. A second connection point (A2) corresponds to a second potential.                                                  At least one further connection point (A3) corresponds to a further potential which is preferably lower than the first and greater than the second potential.  A plurality of K output connections (U, V, W) are provided, which can each be selectively connected to a respective one of the connection points (A1, A2, A3) through the switching device (220). At least one current flowing into the further connection point (A3) is controlled or regulated.
Patent CA-2860083-A1 (CA)
Title: Acidic laundry detergent compositions
Inventor: SADLOWSKI EUGENE STEVEN
IPC: C11D3/20
Filed: 2013-01-17
Abstract: An acidic laundry detergent composition comprising less than about 20% of a surfactant system comprising surfactants selected from the group consisting of anionic surfactants, nonionic surfactants, cationic surfactants and mixtures thereof, wherein the surfactant system has a Hydrophilic Index of greater than or equal to about 9.00 and an organic acidulant at a level such that the ratio of surfactant system to organic acidulant is less or equal to about 3.0 and an alkaline neutralizer added in an amount necessary to raise the neat pH of the detergent composition above or equal to about 2.5 but no higher than or equal to about 3Ø
Patent CA-2861064-A1 (CA)
Inventor: JARRY PHILIPE
IPC: B22D11/20
Filed: 2013-01-08
Abstract: L'invention a pour objet un dispositif de refroidissement direct d'un moule de coulée semi-continue verticale de plaques de laminage ou billettes de filage (3) à trempe progressive par double jet (4 et 5), le premier à sensiblement 32° et le second à sensiblement 22°, de façon simultanée et délivrant sensiblement les mêmes débits et vitesses à partir d'une seule chambre de liquide (2). L'invention a également pour objet un procédé mettant en uvre ledit dispositif, avec ou sans insert graphite (1 ) sur les faces travaillantes et en association avec diverses configurations de faux-fonds.
Patent CA-2861703-A1 (CA)
Inventor: CAMPBELL JOHN L
IPC: H01J49/10
Filed: 2012-11-28
Abstract: In some embodiments, a mass spectrometer capable of performing OzID is disclosed that can provide ozone in situ within an evacuated chamber of the spectrometer, e.g., within a collision cell or within the vacuum chamber of the mass spectrometer. In some embodiments, a corona discharge generated within the evacuated chamber can be employed to convert an ozone precursor delivered to the chamber into ozone.
Patent CA-2863733-A1 (CA)
Inventor: LAI JING
IPC: H04N21/8547
Filed: 2013-05-31
Abstract: The present disclosure provides a method of playing online video at a speed variable in real time, the method comprising: step S1: receiving multimedia source file chosen by the user; step S2: reading out the multimedia source file; step S3: separating audio stream and video stream from the multimedia source file; step S4: decoding the audio stream and the video stream separately; step S5: varying the speed of the audio stream;  step S6:  assigning audio clock of the audio stream whose speed has been varied to video clock of the decoded video stream, and reading out the video clock after assignment;  step S7:  outputting the audio stream and the video stream. The present disclosure also provides a system of playing online video at a speed variable in real time. The method and system of playing online video at a speed variable in real time provided by the present disclosure achieve the goal of playing at variable speed and audio-video synchronization.
Patent CA-2865129-A1 (CA)
Title: Compositions and methods for the treatment of hemoglobinopathies
Inventor: BENDER MICHAEL A
IPC: A61K48/00
Filed: 2013-02-22
Abstract: Provided are compositions and methods for the treatment of hemoglobinopathies such as thalassemias and sickle cell disease. Compositions and methods include one or more endonuclease(s) or endonuclease fusion protein(s), including one or more homing endonuclease(s) and/or homing endonuclease fusion protein(s) and/or CRISPR endonuclease(s) and/or CRISPR endonuclease fusion protein(s): (a) to disrupt a Bell la coding region; (b) to disrupt a Bell la gene regulatory region; (c) to modify an adult human ß-globin locus; (d) to disrupt a HbF silencing DNA regulatory element or pathway, such as a Bell la-regulated HbF silencing region; (e) to mutate one or more ?-globin gene promoter(s) to achieve increased expression of a ?-globin gene; (f) to mutate one or more d-globin gene promoter(s) to achieve increased expression of a d-globin gene; and/or (g) to correct one or more ß-globin gene mutation(s).
Patent CA-2865776-A1 (CA)
Title: Chaussure comportant une cage de support
Inventor: MAHONEY CHRISTOPHER J
IPC: A43B5/06
Filed: 2014-09-30
Abstract: Un article de chaussure comportant une tige ayant une manche et une cage de support qui est libre par rapport à la manche de sorte que la chaussure peut accommoder une pluralité de formes de pied sans égard au maintien des formes de pied dans un état statique ou un état de changement dynamique pendant un cycle de marche à lintérieur de la chaussure. La manche peut être incluse dans la section mi-pied se prolongeant dun côté médian de la chaussure, sur le dessus de lavant du pied, vers un côté latéral de la chaussure. Une section dorteil comprenant un matériau respirant peut être jointe et avancée à la section mi-pied. La cage de support peut être faite dun lamellé comprenant au moins deux couches, comme une couche extérieure structurelle, une couche élastique intermédiaire ou une couche intérieure de renfort, facultativement toutes fusionnées, pour fournir à la cage plusieurs attributs fonctionnels, comme la stabilité, lélasticité ou le renfort de la structure.
Patent CA-2870830-A1 (CA)
Title: Use of alpha-amylase from aspergillus clavatus for saccharification
Inventor: CLARKSON KATHLEEN A
IPC: C12P19/14
Filed: 2013-05-06
Abstract: A fungal alpha-amylase is provided from Aspergillus clavatus (AcAmy1). AcAmy1 has an optimal pH of 4.5 and is operable at 30-75°C, allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AcAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1 + DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Patent CA-2871890-A1 (CA)
Title: Business structure and method for providing financial services to independent contractors and for reduce the risk of a corporate independent contractor being deemed a personal services business
Inventor: BANDALI ALYKHAN
IPC: G06Q50/10
Filed: 2014-11-20
Abstract: In one aspect the invention provides a business structure for the provision of services to an employing entity is provided. The business structure comprises a partnership having at least one managing partner and at least one general partner. The business structure further comprises at least one corporation suitable to provide services to the employing entity. In the preferred embodiment, the general partner is a living human individual and the at least one corporation provides at least some services to the employing entity. Method aspects are also provided.
Patent CA-2872944-A1 (CA)
Title: Procede et systeme de surveillance d'operations de forage
Inventor: THEMIG DANIEL JON
IPC: E21B47/18
Filed: 2013-05-07
Abstract: Cette invention concerne un procédé et un système de surveillance d'opérations de forage. Ledit procédé comprend la génération de données d'accélération à partir de signaux de vibration recueillis dans un puits et le traitement desdites données pour en déduire une condition du puits tel que l'actionnement d'un dispositif et le déplacement et la localisation d'un dispositif d'actionnement.
Patent CA-2876484-A1 (CA)
Inventor: RAZAVI-SHIRAZI FATEMEH
IPC: C02F3/34
Filed: 2013-06-14
Abstract: The microorganism-containing biocatalysts disclosed have a large population of the microorganisms irreversibly retained in the interior of the biocatalysts. The biocatalysts possess a surprisingly stable population of microorganisms and have an essential absence of debris generation from metabolic activity of the microorganisms. The biocatalysts are composed of highly hydrophilic polymer and have an internal, open, porous structure that promotes community phenotypic changes.
Patent CA-2876799-A1 (CA)
Inventor: CHEN JIANLE
IPC: H04N19/184
Filed: 2010-08-13
Abstract: Disclosed is a method of encoding a video, the method including: splitting a current picture into at least one maximum coding unit; determining a coded depth to output a final encoding result according to at least one split region obtained by splitting a region of the maximum coding unit according to depths, by encoding the at least one split region, based on a depth that deepens in proportion to the number of times the region of the maximum coding unit is split; and outputting image data constituting the final encoding result according to the at least one split region, and encoding information about the coded depth and a prediction mode, according to the at least one maximum coding unit.
Patent CA-2879311-A1 (CA)
Inventor: MACNEIL DAVID
IPC: E01C23/00
Filed: 2015-01-22
Abstract: A shield system for a hydrodemolition apparatus has a loop whose ends are secured to opposite sides of a reciprocating nozzle carrier. The loop may be supported by a supporting structure surrounding the frame along which the nozzle carrier reciprocates. The loop overlays portions of one or more gaps through which one or more nozzles extend to work an underlying surface. The nozzles have access to the underlying surface through the gaps under the nozzle carrier, but the balance of the gaps are covered by the loop which is drawn or pushed by the nozzle carrier during reciprocation.
Patent CA-2883004-A1 (CA)
Title: Systeme de vetement d'exterieur incorporant un vetement de base dote de couches exterieures attachables, comme l'ajout de motif de camouflage selon le terrain
Inventor: PIRONE PAUL
IPC: F41H3/00
Filed: 2015-02-25
Abstract: Il est décrit un système servant à fournir plusieurs doublures extérieures échangeables (habituellement minces et légères) pour un vêtement de base pouvant être porté. Le vêtement de base est soit une combinaison intégrale, soit un pantalon, soit un manteau, soit une combinaison des trois et présente plusieurs points dattache. Une première doublure extérieure choisie comprend une configuration qui lui permet dêtre positionnée par-dessus nimporte quel pantalon ou manteau du vêtement de base. La doublure extérieure présente également plusieurs points dattache qui engagent la première série de points dattache. La première doublure présente un premier motif décoratif et, une fois détaché du vêtement de base, peut être substitué à une deuxième doublure de construction identique qui présente un deuxième motif décoratif.
Patent CA-2886023-A1 (CA)
Inventor: CEREZO JASON ROBERT
IPC: C25C5/00
Filed: 2013-09-26
Abstract: An electrode for electrolytic processes, the electrode comprising a conducting bar and a plate attached to the conducting bar, wherein the conducting bar has a conducting member attached thereto to increase the conductivity of the conducting bar.
Patent CA-2887284-A1 (CA)
Inventor: STONG DENNIS
IPC: G06Q40/02
Filed: 2013-10-05
Abstract: Systems, methods, and non-transitory computer-readable mediums storing computer program code implement methods for providing a computer-aided dual-date system and method for accounting. In some cases, the described systems and methods include steps of receiving a plurality of accounting transactions to a computer device, storing the plurality of accounting transactions, and utilizing the plurality of stored accounting transactions to generate a financial statement. In some cases, each accounting transaction includes two dates, namely a transaction date and an accrual date, wherein the accrual date is for any part of the transaction that is linked to an income statement account. In some cases, the accrual date, unlike the transaction date, may be different for each part within the transaction, indicating when the individual parts of the transaction accrued. Inclusion of the dual dates for each transaction can facilitate generation of accounting reports and statements and other accounting duties.
Patent CA-2888128-A1 (CA)
Inventor: PANIAN TYLER DEVIN
IPC: A61M39/20
Filed: 2013-11-01
Abstract: A capping device that includes a cap, a first member, a second member, and a living hinge is provided. The cap is for covering the top of a medical access connector. The first member is connected with the cap. The living hinge is located between the first member and the second member. Capping and uncapping the medical access connector with the cap is transparent to a user that is manipulating the medical access connector.
Patent CA-2890813-A1 (CA)
Inventor: TIJSTERMAN JACOB ARTHUR
IPC: C12M1/00
Filed: 2013-11-08
Abstract: The present invention relates to discontinuous fed batch cell culturing of mammalian cells (more specific CHO cells) with the use of alternating bioreactors in combination with discontinuous separation of biomass from biological substance (more specific monoclonal antibodies) and waste components.
Patent CA-2890886-A1 (CA)
Title: Indole carboxamide derivatives as p2x7 receptor antagonists
Inventor: HILPERT KURT
IPC: A61K31/506
Filed: 2013-12-11
Abstract: The invention relates to indole carboxamide derivatives of formula (l), (see formula I) to their preparation to and their use as pharmaceutically active compounds.
Patent CA-2892343-A1 (CA)
Title: Hydrocarbon stimulation by energetic chemistry
Inventor: LAWRENCE SALLY
IPC: C09K8/74
Filed: 2015-05-22
Abstract: Disclosed are methods and compositions for stimulating a hydrocarbon formation by generating heat and/or pressure in the formation, in either a fracturing or matrix treatment. This invention utilizes reactive fluids which comprise energetic chemistry that reacts in the formation to create heat and/or pressure. The heat may reduce the viscosity and increase the mobility of heavy oil, and/or the pressure may initiate or extend fractures in the hydrocarbon bearing formation. The reactive fluid may be buffered to slow the reaction and include an encapsulated activator to accelerate the reaction after suitable delay or when the fluid is placed in a zone of interest. Reactive fluids may be sequentially used, wherein each reactive fluid is successively less energetic than the preceding reactive fluid.
Patent CA-2892623-A1 (CA)
Inventor: KIM YONG SUNG
IPC: C07K16/18
Filed: 2013-11-27
Abstract: La présente invention concerne une paire de variants du domaine CH3 d'un anticorps, un procédé pour la préparation de celle-ci, et une utilisation associée, une mutation étant induite dans le domaine CH3 afin d'améliorer le rendement de formation d'une région constante de chaîne lourde d'hétérodimère d'un anticorps. L'hétérodimère de domaine CH3 selon la présente invention, forme une région constante de chaîne lourde d'hétérodimère à haute efficacité de 90 à 95 % ou plus et présente également une excellente thermostabilité. La région constante de chaîne lourde d'hétérodimère comprenant l'hétérodimère de domaine CH3 peut construire un anticorps monoclonal bispécifique qui reconnaît simultanément deux types d'antigènes. L'hétérodimère de domaine CH3 de la présente invention, et l'anticorps bispécifique ou protéine de fusion d'une région constante d'anticorps le comprenant peuvent être utilisés pour le traitement ou la prévention d'une maladie associée à un antigène cible ou une protéine cible.
Patent CA-2892739-A1 (CA)
Inventor: ASSEFA HAREGEWIN
IPC: A61P29/00
Filed: 2007-12-21
Abstract: Methods and compositions for the treatment of skin disorders (e.g , acne, rosacea) are described.
Patent CA-2894213-A1 (CA)
Inventor: CASTLE LINDA A
IPC: C12N15/82
Filed: 2013-12-20
Abstract: Compositions and methods are provided to detoxify an auxin-analog herbicide through the use of at least one GH3 polypeptide having amino acid/auxin analog herbicide conjugation activity. Such GH3 polypeptides in the presence of an auxin-analog herbicide will produce an amino acid/auxin-analog conjugate having reduced herbicidal activity. Various methods of employing the GH3 polypeptides and the polynucleotides encoding the same are provided. Such methods include methods to detoxify an auxin-analog herbicide comprising applying to a plant, a plant cell or a seed an auxin-analog herbicide, wherein the plant, plant cell or seed comprises a heterologous polynucleotide encoding a GH3 polypeptide, and expression of the GH3 polypeptide produces a non-herbicidal aspartate/auxin-analog conjugate or a glutamate/auxin-analog conjugate. Additional methods for controlling at least one weed in an area of cultivation comprising a crop or a seed of the crop are provided, as are methods of detoxifying a contaminated material having an auxin-analog herbicide.
Patent CA-2895264-A1 (CA)
Inventor: KAMIYAMA YOUICHI
IPC: B60B21/02
Filed: 2012-12-17
Abstract: This vehicle wheel (1) is characterized by being provided with only two auxiliary air chamber members (10a, 10b) each as a Helmholtz resonator having an auxiliary air chamber that communicates with a tire air chamber via a communication hole (18a), and characterized in that the respective communication holes (18a) of the auxiliary air chamber members (10a, 10b) are provided apart from each other in a wheel circumferential direction (X) so as to form approximately a right angle around a wheel rotation center (Ax).
Patent CA-2895404-A1 (CA)
Inventor: SCHMEES NORBERT
IPC: A61K31/4985
Filed: 2013-12-17
Abstract: The invention concerns BET-protein-inhibiting, in particular BRD4-inhibiting, dihydropyridopyrazinones of general formula (I), in which A, X, R1, R2, R3, R4, R5, R6, R7 and n have the meanings given in the description, intermediates for producing the compounds according to the invention, pharmaceutical agents containing the compounds according to the invention, and their prophylactic and therapeutic use in hyperproliferative diseases, in particular tumour diseases. The invention further concerns the use of BET-protein-inhibitors in viral infections, neurodegenerative diseases, inflammatory illnesses, atherosclerotic diseases, and in male fertility control.