baber/WOPTO huggingface dataset:
Patent EP-0675729-B1 (EP)
Inventor: LANE DAVID PHILIP
IPC: C12N9/12
Filed: 1993-11-26
Granted: 1999-06-02
Abstract: PCT No. PCT/GB93/02438 Sec. 371 Date Jul. 24, 1995 Sec. 102(e) Date Jul. 24, 1995 PCT Filed Nov. 26, 1993 PCT Pub. No. WO94/12202 PCT Pub. Date Jun. 9, 1994A class of mutant forms of p53 protein, such as His273 and Lys285, which are defective in conversion from the latent to the activated state by casein kinase II, but with the ability to be activated for specific DNA binding by the action of ligands such as monoclonal antibody PAb421 and heat shock protein DnaK. Activation of these mutants, which are found at high levels in certain types of tumour, can potentially lead to selective growth arrest and induction of apoptosis in the tumor cells. p53 can be constitutively activated also by deletion of the C-terminal 30 amino acids. p53 activated in this way, or by ligand binding, can be administered for the purposes of tumour or cell growth suppression.
Patent EP-0684780-B1 (EP)
Inventor: JOOSTENS JEAN-PHILIPPE ALAIN
IPC: A47K3/30
Filed: 1994-02-18
Granted: 1997-01-02
Abstract: Disclosed herein is a sealing system for use with a shower enclosure of the type having an open side portion, a shower base (15), and a shower door (20). A track (24) is mounted to the base (15) with a sleeve (25) adjustably disposed on the track (24) for vertical movement. The sleeve (25) has a seal (71) on its upper surface (41) directly under the door (20) when the door (20) is closed. A fastener allows a user to secure the sleeve (25) and seal (71) in a proper vertical alignment relative to the base (15).
Patent EP-0690787-B1 (EP)
Inventor: HAMMOND JOHN MICHAEL
IPC: B29C48/08
Filed: 1994-03-17
Granted: 1997-09-10
Abstract: Procédé et dispositif de fabrication de métal revêtu possédant un ensemble de trempe où un jet (ou des jets) de liquide de refroidissement sont dirigés vers le métal revêtu par des buses submergées au-dessous de la surface dudit liquide contenu dans un réservoir et où le liquide de refroidissement est recyclé et refroidi, de façon à commander avec précision le refroidissement du métal revêtu.
Patent EP-0647280-B1 (EP)
Inventor: OHSHIMA ATUSHI
IPC: C12Q1/68
Filed: 1994-03-01
Granted: 2003-11-26
Abstract: Procédé de synthèse de nouveaux ADN utiles à brin unique ayant une structure tige - boucle. Le procédé concerne la synthèse in vivo et in vitro de ces ADN. L'invention concerne également des vecteurs de réplication qui produisent ces ADN. On décrit ces ADN, ainsi que leur utilisation. Ces ADN peuvent être utilisés pour produire des mutations aléatoires, et ils se prêtent à une réplication par une variante de la méthode d'amplification enzymatique du génome. On peut également les utiliser pour la régulation de la fonction génique. On décrit également d'autres utilisations.
Patent EP-0714266-B1 (EP)
Title: Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same
Inventor: DORY JACQUES
IPC: A61B18/00
Filed: 1994-07-26
Granted: 1998-10-21
Abstract: The therapy and imaging probe of the invention comprises a probe body (20') of an elongate shape defining a general axis (X-X), one imaging transducer (40') for transmitting imaging waves, and one therapy transducer (30') for transmitting therapy waves. The imaging transducer is mounted on first support means providing translational movement of the imaging transducer within the probe, parallel to the general axis (X-X) of the probe, between a withdrawn position and an extended position. The therapy transducer is mounted on second support means providing rotation of the therapy transducer within the probe, about an axis of rotation (X1-X1) parallel to the general axis (X-X) of the probe but offset with respect to the imaging transducer, to allow rotation of the therapy transducer between a withdrawn position and a treatment position. In the withdrawn or non-active position of the therapy transducer, the imaging transducer may be brought by translational movement to its extended position to occupy the place occupied by the therapy transducer in its treatment position. Thus, the imaging transducer may form an image of a region for treatment by the therapy transducer. In the treatment position of the therapy transducer, the imaging transducer is at its withdrawn position. The therapy transducer, during the transmission of therapy waves, directly transmits the therapy waves in a direction substantially identical to the direction in which the imaging transducer transmits the imaging waves when imaging waves are being transmitted.
Patent EP-0722590-B1 (EP)
Inventor: LIPPS RANDALL A
IPC: A61B19/02
Filed: 1994-07-13
Granted: 2002-10-30
Abstract: The invention provides methods and apparatus for dispensing items from a dispensing unit. According to the invention, the dispensing unit comprises a plurality of locations in which the items are held, a processor in which records corresponding to the items on the unit are stored, and a plurality of item switches corresponding to the locations in which the items are held. The item switches are connected to the processor so that a user of the dispensing unit can input records of items removed from the unit into the processor. The apparatus described is particularly suited for dispensing medical supplies although the apparatus will be usable for other types of items as well. Preferred embodiments will include a plurality of visual indicators, typically in the form of light emitting diodes, corresponding to the locations in which the items are held. Upon selection of a desired item from a list of items held by the unit, the visual indicator corresponding to the item is actuated so that the user can locate the desired item quickly and conveniently with the help of the visual indicator.
Patent EP-0710179-B1 (EP)
Inventor: MAUK HANNS
IPC: C08L23/02
Filed: 1994-07-15
Granted: 1997-02-26
Abstract: The description relates to multi-layer plastic webs or plates consisting of a coating layer, especially a transparent one, and at least one further layer, at least one layer having at least one ethylene-alkyl acrylate copolymer. The description also relates to a process for producing the plastic webs or plates. The plastic webs or plates can be used as artificial veneers, decorative films, wall, ceiling or floor coverings.
Patent EP-0717712-B1 (EP)
Inventor: CRISTOFANI ALESSANDRO
IPC: B65D71/08
Filed: 1994-09-14
Granted: 1997-06-11
Abstract: Multiple packaging for bottles (1) consisting of a film (2) of heat-shrinkable plastic hot-applied to a plurality of bottles arranged alongside one another in parallel rows and comprising a series of incisions (3) in the regions of the planes separating adjacent rows of bottles. The packaging allows single rows of bottles to be detached, the latter being kept integral by the torn portion of packaging. A preferred method for manufacturing the packaging is described, based on a film of heat-shrinkable plastic provided with incisions.
Patent EP-0723588-B1 (EP)
Inventor: WOZNEY JOHN M
IPC: C07H21/04
Filed: 1994-09-07
Granted: 2007-10-24
Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
Patent EP-0802877-B1 (EP)
Inventor: STOCKWELL COLIN
IPC: B65D41/26
Filed: 1994-10-14
Granted: 1999-03-10
Abstract: A detergent dispenser comprising a first part (2) in the form of a closure which normally serves to seal a detergent container, the closure having a closed top (4), a dependent skirt (5a, 5b) and an open mouth (6), and a second part (3) which is releasably engageable with the closure over its open mouth, the second part having an aperture (15) for dispensing detergent.
Patent EP-0665051-B1 (EP)
Inventor: BOATMAN JACK K
IPC: B01F23/47
Filed: 1995-01-12
Granted: 1997-12-17
Abstract: A process and apparatus for mixing fluid substances having different viscosities. A flow of a major fluid substance having a higher viscosity is segmented into a plurality of fluid substance streams (86) travelling substantially in parallel in close proximity. A flow of a fluid additive having a lower viscosity is introduced into the flow of the major fluid substance at one or more points (82) between the fluid substance streams to obtain a combined flow. The combined flow is then mixed to provide a homogeneous mixture. The major fluid substance may be an extrudate. <IMAGE>
Patent EP-0674184-B1 (EP)
Inventor: VON PIEVERLING KLAUS DR
IPC: G01S13/91
Filed: 1995-02-28
Granted: 1999-09-08
Abstract: The method uses a radar equipment (RG) mounted on an overbridge (BR) to direct a steeply inclined beam (RS) on to each vehicle (FZ) entering the area of road (SB) covered by the radar antenna (ANT). The shape of the vehicle is recognisable from the different components of the radar echo associated with scattering from its edges and corners, and with specular reflection from smooth surfaces. Fine identification is based on continuous measurement of the Doppler frequency of the variation in slope of the tangent to the outline of the vehicle. Additionally, a speed of vehicle is measured as a basis for obtaining horizontal profile data, e.g. vehicle length.
Patent EP-0672666-B1 (EP)
Inventor: GODEL THIERRY
IPC: A61K31/41
Filed: 1995-03-03
Granted: 2001-07-25
Abstract: Aminomethyl-substd. oxadiazolyl-imidazodiazepines of formula (I) and their addn salts are new: A and C atoms  alpha  and  beta form a gp of formula e.g. (A<1>):Q = a gp. of formula e.g. (Q<1>):R<1>, R<2> = H; lower alkyl,etc.;or NR<1>R<2> = 5-8 membered heterocycle opt. contg. a further hetero atom or carrying a fused benzene ring; R<3> = H and R<4> = lower alkyl; or R<3>+R<6> = H; halo;etc.; and C atom gamma  has the S configuration when R<3> is other than H.
Patent EP-0721737-B1 (EP)
Inventor: KOCK GERD DIPL-ING
IPC: A21C5/04
Filed: 1995-10-19
Granted: 2001-06-27
Abstract: Dough portioning and kneading machine allowing two or more doughs of differing recipes to be processed simultaneously comprises at least two separate dough hoppers (10, 11), with a transfer chamber (8, 9) following each. Within each transfer chamber is a sliding transfer piston (13, 14). After each transfer chamber comes a sizing chamber, moving between two positions, one open to the transfer chamber, the second clear of it. Inside each sizing chamber (34) is a sliding, dispensing piston (36). In the first position this partly opens the sizing chamber, in the second, it empties it.
Patent EP-0710542-B1 (EP)
Inventor: BLAUHUT WILFRIED DIPL-ING
IPC: B30B5/06
Filed: 1995-10-26
Granted: 1999-12-29
Abstract: Upper (1) and lower (2) endless steel strips from press belts of a heatable and coolable double belt press for mfr. of fibre-reinforced thermoplastics. The sides of the press chamber contg. the material to be pressed (4) are sealed off by a porous profile (5) with machined-out recessed for soldered-in-pipes (7) to supply water to remove heat and form a solidified edge in the material. Water is sprayed in at the transition from regions of low press pressure to regions of higher pressure.
Patent EP-0710576-B1 (EP)
Inventor: VOEGLER HANS-JUERGEN
IPC: B60C9/06
Filed: 1995-10-28
Granted: 2000-01-12
Abstract: The tyre has several carcass inlays around the circumference of the tyre, reaching from bead-to-bead in the axial direction. These consist of solid reinforcements embedded in rubber. The ends (9', 9'') of ≥ 1 carcass inlay (9), which are directed around the circumference, overlap each other, at least near the side walls. There is ≥ 1 further rubber layer (7) around the circumference, radially outside the carcase (9). It is similarly has ends overlapping (7', 7'') in the circumferential direction, near the side walls, and at the same circumferential location as the overlap of the carcass layer (9). Also claimed is mfr. of the tyre.
Patent EP-0723868-B1 (EP)
Inventor: HAYAO SAKAE
IPC: B41J2/175
Filed: 1995-08-08
Granted: 1999-12-22
Abstract: An ink cartridge holding box for refilling a used ink cartridge with ink has an adhesive layer on a platform installed inside the box. The central area of the adhesive layer is raised so that the adhesive layer is in a contact shape, conforming to any unevenness of the underside of the used ink cartridge and for sealing the vent hole opened in the underside of the cartridge. An ink refill kit comprises an instruction sheet and a cartridge holding box. The box is placed in a working area located at the center of the instruction sheet and the sheet has an instruction area describing steps to be taken for refilling ink. <IMAGE>
Patent EP-0677241-B1 (EP)
Inventor: ARON JEROME
IPC: A01D78/10
Filed: 1995-04-04
Granted: 1999-12-08
Abstract: The haymaking machine has a swathing rotor (1) carried by a frame (2) which can be fastened to a tractor. The rotor is rotated by a hydraulic motor (29) which is supplied through hydraulic pipes (30,31). The frame carries in addition a foldable protector (16) which partially surrounds the rotor. A stop device (32) is placed on one of the hydraulic pipes going from the hydraulic motor. A stop activator (35) is connected to the protector foldable parts. The stop device has a slide distributor (33) having several position. The distributor activator is constituted by a rod connected to the two foldable parts of the protector with a further rod which is connected to the distributor slide. The first rod has at each of its ends an oblong hole in which is engaged the end of a lever on the protector folding parts. <IMAGE>
Patent EP-0738219-B1 (EP)
Inventor: VERBO ULYSSE
IPC: B60T13/57
Filed: 1994-11-29
Granted: 1997-06-04
Abstract: L'invention concerne un servomoteur pneumatique d'assistance au freinage, comportant une enveloppe (10) possédant un axe de symétrie (X-X'), séparée de façon étanche par une structure de paroi mobile (12, 20) en une chambre avant (14) reliée en permanence à une source de dépression, et une chambre arrière (16) reliée sélectivement à la chambre avant (14) ou à l'atmosphère extérieure par une valve à trois voies (36) actionnée par un plongeur (28) coulissant dans un alésage (26) de la paroi mobile (12, 20) et solidaire d'une tige de commande axiale (30) soumise à l'action d'un ressort de rappel (68) disposé dans un espace annulaire (32) entre la tige de commande (30) et une partie tubulaire arrière (22) de la structure de paroi mobile (12, 20) faisant saillie à l'extérieur de l'enveloppe (10), la valve à trois voies (36) étant disposée dans cette partie tubulaire arrière (22) et comportant un élément de clapet (36) coopérant par une première surface annulaire (A) avec un premier siège de clapet (28a) formé sur le plongeur (28) et par une seconde surface annulaire (B) avec un second siège de clapet (20a) formé sur la paroi mobile (20). Selon l'invention, les première (A) et seconde (B) surfaces annulaires sont dans des plans transversaux différents, les première (A) et seconde (B) surfaces annulaires étant raccordées par une surface (C) de forme générale tronconique de guidage de l'air en mouvement en aval du premier siège de clapet (28a) lorsqu'il est éloigné de la première surface annulaire (A).
Patent EP-0732939-B1 (EP)
Title: Preparation and use of immunoconjugates comprising a VL-chain glycosylated at the Asn in position 18
Inventor: HANSEN HANS J
IPC: G01N33/563
Filed: 1994-12-05
Granted: 2004-10-20
Abstract: The present invention relates to immunoconjugates comprising an antibody fragment which is covalently bound to a diagnostic or therapeutic principle through a carbohydrate moiety in the light chain variable region of the antibody fragment. The invention also relates to immunoconjugates comprising an antibody moiety that is an intact antibody containing a glycosylation site in the light chain variable domain which has been introduced into the antibody by mutating the nucleotide sequence encoding the light chain. The resultant immunoconjugates retain the immunoreactivity of the antibody fragment or intact antibody, and target the diagnostic or therapeutic principle to a target tissue where the diagnostic or therapeutic effect is realized. Thus, the invention contemplates the use of such immunoconjugates for diagnosis and immunotherapy. The invention further relates to methods for preparing such immunoconjugates.
Patent EP-0752068-B1 (EP)
Inventor: KOENIG GOTTFRIED
IPC: F16B25/10
Filed: 1995-03-07
Granted: 1998-10-07
Abstract: Die Erfindung betrifft einen Bohrer mit einem Bohrschaft (1), insbesondere mit einem ein selbstfurchendes Gewinde (18) aufweisenden Schraubenschaft, und einem dem Antriebsende des Schaftes gegenüberliegend angeordneten gabelförmigen Bohrplättchen (10) aus hartem Material, das in eine Halterung im Schaft (1) eingesetzt ist, die zwei diametral zueinanderliegende Nuten (3, 4) im Schaft zur Aufnahme von Zinken (13, 14) des Bohrplättchens (10) aufweist. Der Schaft (1) endet stumpf in einer im wesentlichen radialen Abschlussfläche, aus der die Nuten (3, 4) zum Antriebsende hin derart verlaufen, dass allein die in die Nuten axial eingedrückten Zinken (13, 14) des Bohrplättchens (10) sowohl dieses selbsthemmend am Schaft (1) halten als auch das Drehmoment vom Schaft (1) auf das Bohrplättchen (10) übertragen.
Patent EP-0729998-B1 (EP)
Inventor: SHO KAZUHIKO
IPC: C08J5/18
Filed: 1995-04-04
Granted: 2002-07-17
Abstract: Feuille en résine de styrène d'une épaisseur de 0,10 à 2,5 mm, présentant un facteur de retrait à la chaleur de 20 % ou moins, et moulage produit à partir de cette feuille. La feuille est obtenue à partir d'une composition de résine de styrène renfermant 100 parties en poids d'une résine de styrène modifié au caoutchouc et 3 à 15 parties en poids de résine de terpène. La résine de styrène modifiée au caoutchouc renferme 85 à 92 % en poids d'une phase continue d'un polymère composée de 45 à 60 % en poids d'unités monomère de styrène, 5 à 15 % en poids d'alkyle (C2-C4) acrylate et/ou d'unité monomère de méthacrylate, de 25 à 50 % en poids d'unités monomères de méthacrylate de méthyle et 15 à 8 % en poids de particules d'élastomère caoutchouteux en dispersion d'un calibre moyen de 0,4-0,9 νm et incluant un copolymère-bloc styrène-butadiène binaire renfermant 25 à 40 % en poids de styrène. Cette feuille présente d'excellentes qualités de transparence, de résistance et de rigidité ainsi qu'une excellente aptitude au moulage dans les procédés de fabrication à chaud. Elle n'entraîne aucune altération de la transparence du produit et se prête à des utilisations telles que l'emballage de denrées alimentaires, l'enrobage de composants électriques, etc.
Patent EP-0705824-B1 (EP)
Inventor: WATANABE NANAO
IPC: C07D241/04
Filed: 1995-04-20
Granted: 2002-08-07
Abstract: Procédé de production de N-tert-butyl-2-pipérazinecarboxamide à activité optique, servant p. ex. d'intermédiaire pour des médicaments à haute pureté optique, consistant à effectuer une résolution optique de la (R,S)- N-tert-butyl-2-pipérazinecarboxamide en utilisant de l'acide lactique, malique ou tartrique. L'inverse optique inutilisable restant dans ladite phase de résolution optique peut être rendu utilisable en racémisant la N-tert-butyl-2-pipérazinecarboxamide à activité optique en présence d'un composé basique puis en procédant à une nouvelle résolution optique.
Patent EP-0787005-B1 (EP)
Inventor: HALL BONNIE JOY
IPC: A61K31/16
Filed: 1995-07-21
Granted: 2002-03-27
Abstract: The present invention relates to compositions for treating acne and other skin lesions and also to methods of treatment utilizing these compositions. These compositions and methods of treatment employ benzoyl peroxide, a compound for reducing the skin irritation associated therewith, and a topical carrier.
Patent EP-0775325-B1 (EP)
Inventor: HARMAN MURRAY R
IPC: G02B6/38
Filed: 1995-08-11
Granted: 1999-05-26
Abstract: A consumable fusion block for fusing optical fibers includes non-conducting substrate with at least one flat surface. A pair of electrodes overlay the flat surface of the substrate and are spaced apart on either side of a passline such that each electrode tip end is adjacent the passline. A space between the electrode tips defines an arc region which can be covered to form a semi-enclosed arc region. A method is also provided for manufacturing a plurality of fusion blocks from a single slab of non-conducting material by overlying the non-conducting material with a length of conducting material, bonding the conducting material to the non-conducting material, and cutting the slab into smaller fusion blocks.
Patent EP-0779841-B1 (EP)
Inventor: SAND KJELL
IPC: B65H51/16
Filed: 1995-07-31
Granted: 2002-10-02
Abstract: An ejection nozzle for transport of fiber thread pieces by means of compressed air, e.g. reinforcement material for manufacturing fibre reinforced plastic products, from a cutter to a moulding cavity. The nozzle is provided with a common flow duct for the compressed air and the fibre thread pieces. The flow duct runs past at least one reflector surface (15) for the air flow, and at least one opening (16) for evacuation of air to the surroundings is located along the flow duct.
Patent EP-0732251-B1 (EP)
Inventor: ONISHI ICHIRO
IPC: B62B7/06
Filed: 1995-10-19
Granted: 2002-01-02
Abstract: To reliability accomplish a lock state of a grip rod in a linear state and a bent state in a grip rod of a foldable baby carriage, first and second portions (4, 5) of the grip rod (3), which are interconnected by a joint (6), are interconnected by a rigid link member (28) so that the first and second portions operate symmetrically with each other with respect to the joint (6). Because the angles formed by these first and second portions (4, 5) to the joint (6) can be kept at the same angle in this way, lock members (23, 24) can be reliably engaged with lock recesses (19, 20) for the open state or with lock recesses (21, 22) for the closed state.
Patent EP-0796122-B1 (EP)
Inventor: CHOUDHURY HRISHIKESH
IPC: A61M39/02
Filed: 1995-11-15
Granted: 2001-10-31
Abstract: A valve including a substantially rigid cannula and a valve member positioned for operable communication with the cannula. The valve member is formed from a substantially resilient material, having a slit extending therethrough, and movable with respect to the cannula between a first closed position and a second open position. The slit is substantially closed by the resiliency of the material of the valve member when the valve member is positioned in the first closed position and the cannula cooperates to extend through the slit during movement of the valve member from the first closed position to the second open position to establish a fluid flow path through the cannula and the valve member. A sealing member is also provided independent from a flow of fluid within the fluid flow path to provide positive sealing of the slit when the valve member is positioned in the first closed position.
Patent EP-0796340-B1 (EP)
Inventor: VALENTINE BRIAN PETER
IPC: C12R1/465
Filed: 1995-12-07
Granted: 2003-02-26
Abstract: Improved methods for the preparation of clavams by fermentation of a clavam-producing organism in a suitable medium wherein the ammonium levels are kept low so as to avoid repression of enzymes, particularly urease, are disclosed.
Patent EP-0746500-B1 (EP)
Inventor: TROGER ERWIN
IPC: B65B43/26
Filed: 1995-12-19
Granted: 1998-03-04
Abstract: The invention concerns an unfolding station (B) for folded plastic fruit crates which are taken one by one from a stack in an upstream withdrawal station (A) and stacked at a downstream stacking station (C) for the unfolded crates (8). The crates (8), whose side walls (8l, 8b) are folded down onto the crate floor (8d), are unfolded when raised in relation to the feed and discharge line of the unfolding station.