baber/WOPTO huggingface dataset:
Patent SG-10201806917P-A (SG)
Title: Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
Inventor: LYON ROBERT
Filed: 2014-10-14
Abstract: PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS The present invention provides Ligand-Drug Conjugates comprising a PEG Unit in a parallel orientation to the Drug Unit. The invention provides inter alia, Ligand- Drug Conjugates (LDCs), methods of preparing and using them, and intermediates thereof. The Ligand- Drug Conjugates are stable in circulation, yet capable of inflicting cell death on targeted cells or inhibiting proliferation of targeted cells once its drug cargo is released in the vicinity or within targeted cells. In principle embodiments, an LDC of the present invention is represented by the structure of Formula I. [Figure 1]
Patent SG-10201808277V-A (SG)
Title: Catalytic Cracking Process with Increased Production of a Gasoline Having a Low Olefin Content and a High Octane number
Inventor: GONG JIANHONG
Filed: 2018-09-24
Abstract: The present disclosure relates to a catalytic cracking process comprising the following steps: i) subjecting a heavy feedstock oil to a catalytic cracking reaction to obtain a catalytic cracking reaction product; ii) separating the catalytic cracking reaction product to obtain a catalytic cracking gasoline and a catalytic cracking light cycle oil; iii) splitting the catalytic cracking gasoline to obt ain a light gasoline fraction, a medium gasoline fraction and a heavy gasoline fraction; iv) subjecting the catalytic cracking light cycle oil to hydrogenation to obtain a hydrogenated light cycle oil); v) mixing a portion of the light gasoline fraction with at least a portion of the hydrogenated light cycle oil to obtain a 10 mixed fraction; vi) subjecting the mixed fraction to a catalytic cracking reaction; and vii) subjecting a portion of the medium gasoline fraction to a catalytic cracking reaction. The process of the present application is capable of producing more catalytic cracking gasoline, reducing the olefin content of the catalytic cracking gasoline, and increasing its octane number. 15 Fig. 1
Patent SG-10201809070Q-A (SG)
Title: Multi-stage stirred reactor having reduced back mixing
Inventor: FALΒ SEBASTIAN
Filed: 2015-04-20
Abstract: Multi-stage stirred reactor having reduced back mixing The present invention relates to a multistage stirred reactor, comprising a multiplicity of mutually adjacent reaction chambers and stirring elements for mixing the contents of at least one of the 5 reaction chambers, wherein, between adjacent reaction chambers, there is in each case provided at least one opening that can be closed by means of closure means, such that in the open state there is a fluidic connection between the adjacent reaction chambers and in the closed state the adjacent reaction chambers are separated from one another. At least one of the closure means (300, 310, 320) is connected to an actuation rod (500, 510, 520) that is guided out of the stirred reactor. The 10 actuation rod (500, 510, 520) can be moved back and forth between at least one first position and a second position, by rotation and/or displacement, wherein in the first position closure means (300, 310, 320) that are connected to the actuation rod (500, 510, 520) effect an open state of the opening assigned to them and in the second position closure means (300, 310, 320) that are connected to the actuation rod (500, 510, 520) effect a closed state of the opening assigned to them. 15 FIG. 1
Patent SG-11201406548W-A (SG)
Title: Anti-malarial agents
Inventor: GILBERT IAN HUGH
IPC: C07D215/52
Filed: 2013-03-14
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 17 October 2013 (17.10.2013) WIPOIPCT (10) International Publication Number WO 2013/153357 A1 (51) International Patent Classification: C07D 215/52 (2006.01) A61P 33/06 (2006.01) A61K31/4725 (2006.01) (21) International Application Number: PCT/GB2013/050633 (22) International Filing Date: 14 March 2013 (14.03.2013) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1206280.8 10 April 2012 (10.04.2012) GB (71) Applicant: UNIVERSITY OF DUNDEE [GB/GB]; Neth- ergate, Dundee, DDI 4HN (GB). (72) Inventors: GILBERT, Ian Hugh; c/o University of Dun­ dee, Nethergate, Dundee, DDI 4HN (GB). NORCROSS, Neil; c/o University of Dundee, Nethergate, Dundee, DDI 4HN (GB). BARAGANA RUIBAL, Beatriz; c/o Univer­ sity of Dundee, Nethergate, Dundee, DDI 4HN (GB). PORZELLE, Achim; c/o Peakdale Molecular Ltd, Peak- dale Science Park, Sheffield Road, Chapel-en-le-Frith, High Peak SK23 0PG (GB). (74) Agent: HARRISON GODDARD FOOTE; Delta House, 50 West Nile Street, Glasgow, G1 2NP (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: ANTI-MALARIAL AGENTS l> m m T-H o CJ (57) Abstract: The present invention relates to a novel class of quinolone-4-carboxamide Pf5D7 inhibitors of general formula (I) (Formula (I)) wherein R , R , R , 1 2 3 R , R , 4 5 R , 6 R , 7 R 8 and X are as defined herein, their to use in medicine, and in the treatment of mal­ aria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.
Patent SG-11201807917R-A (SG)
Title: Method and device for linking to account and providing service process
Inventor: YIN JUN
IPC: H04L29/06
Filed: 2017-03-03
Abstract: Implementations of the present application provide methods and devices for linking to an account and providing service processing. In the method, after receiving a linking request sent by a user terminal device, an uncertified server can return to the terminal device a predetermined instruction that enables the terminal device to access 5 a certified server. Based on the predetermined instruction, the terminal device can send a real service account of a user used for service processing, so the certified server can generate a virtual service account corresponding to the real service account, and return the virtual service account to the user terminal device. After receiving the virtual service account sent by the user terminal device, the uncertified server can link 10 the virtual service account to a user account that is registered by the user with the uncertified server. It can be seen from the previously described method that, when the uncertified server performs service processing, the user does not need to enter the real service account used for service processing each time, thereby reducing the complexity of service processing for the user and bringing convenience to the user 15 during service processing.
Patent SG-11201901754P-A (SG)
Title: Working apparatus and working method
Inventor: IKUSHIMA KAZUMASA
IPC: G01B11/00
Filed: 2017-09-29
Abstract: [Problem] To provide a work apparatus and a work method whereby work can be obtained that is free of variations among a plurality of work heads having machine differences. [Solution] A work apparatus and a work method that uses the apparatus, the work apparatus provided with n (where n is a natural number equal to 2 or greater) work heads for performing the same work, a stage for retaining a work object, a first-direction drive device for moving the stage and the work heads relative to each other, a second-direction drive device for moving the stage and the work heads relative to each other, a third-direction drive device for moving the stage and the work heads relative to each other, a work amount measurement device for measuring the work amount of each work head, and a control device, the first-direction drive device being capable of moving each of the n work heads independently in a first direction, and the second-direction drive device being provided with a second-direction main drive device for moving the n work heads in a second direction simultaneously and a second-direction secondary drive device for moving each of n-1 work heads of the n work heads independently in the second direction. Figure 1
Patent SG-11201906092Q-A (SG)
Title: Method and device for processing client end microphone-connection live broadcast
Inventor: CHEN QING
IPC: H04L29/06
Filed: 2017-10-23
Abstract: METHOD AND DEVICE FOR PROCESSING CLIENT END MICROPHONE CONNECTION LIVE STREAMING The present application provides a method and device for processing client end microphone connection live streaming. The method includes the steps of: receiving a microphone connection request sent by a primary microphone in a first live stream room and intended for a primary microphone in a second live stream room; sending the microphone connection request to the primary microphone in the second live stream room; obtaining live streaming data of the first live stream room and live streaming data of the second live stream room after receiving response information to microphone connection request from the primary microphone of the second live stream room; sending the live streaming data of the first live stream room to a corresponding client end of the second live stream room, and sending the live streaming data of the second live stream room to a corresponding client end of the first live stream room. The present application can avoid loss of users and virtual gifts of the streamer during a primary microphone connection between different live stream rooms. (Fig. 2a)
Patent AT-406575-B (AT)
Inventor: MUELLEDER GERHARD DIPL ING
IPC: B65D45/30
Filed: 1998-03-12
Granted: 2000-06-26
Abstract: The invention proposes a container, in particular can, made of metal or plastic, having a preferably drawn-in bottom container part and a screw cap, which each have corresponding retainer profilings in the form of thread segments, the top edge of the bottom container part being a rolled edge which is characterized in that the rolled edge is rolled outwards and retains a sleeve on which the retaining profilings of the bottom container part are arranged. <IMAGE>
Patent DK-165588-B (DK)
Inventor: BERGSTROEM ANDERS
IPC: B65G47/46
Filed: 1988-02-17
Abstract: Articles conveyed one after another on a suppyling conveyor (1) are received by a deflecting part (7) and are deflected by 90 DEG  from the travelling direction of said supplying conveyor (1) and are deposited by a chute (9) onto the surface of a receiving conveyor (2) travelling substantially at right angles to the supplying conveyor (1). By moving the deflecting part (7) parallel to the travelling direction of the suppyling conveyor (1) the chute can be positioned selectively above a desired one of a plurality of receiving conveyors (2) arranged side by side.
Patent HU-212527-B (HU)
Title: Diaphragm of a press designed to separate liquids and solids
Inventor: HARTMANN EDUARD
IPC: B30B9/22
Filed: 1991-06-21
Abstract: PCT No. PCT/CH91/00135 Sec. 371 Date Mar. 3, 1992 Sec. 102(e) Date Mar. 3, 1992 PCT Filed Jun. 21, 1991 PCT Pub. No. WO92/00847 PCT Pub. Date Jan. 23, 1992.A diaphragm (1) in a press vessel of a press intended for separating liquid and solid materials consists of two semicircular diaphragm parts (2) facing the front walls of the press vessel and of a diaphragm part (8) connected with these parts (2) on both sides and approximately corresponding to half the outer vessel wall. The diaphragm parts (2, 8) are formed from fabric (3, 13) with plastic coating on both sides and, semicircular diaphragm parts (2) are divided into segments. At least one of the thread systems forming a fabric (3) is aligned to a radial center bisector of each segment.
Patent RS-49791-B (RS)
Inventor: KLAUS DR RUDOLF
IPC: A61P31/04
Filed: 1997-09-09
Abstract: Modifikovane amino kiseline, opšte formule u kojoj R označava nerazgranatu C1-3-alkil grupu kojaje supstituisana u ω-položaju sa C 5-7cikloalkil grupom, sa jednom ili dve fenil grupe, sa l-naftil, 2-naftil ili (4-bifenilil) grupom, dok aromatske grupe dodatno mogu biti supstituisane sa atomom fluora, hlora ili broma, ili sa metil, metoksi, amino ili acetilamino grupom, sa 2-pirolil, 3-pirolil, piridinil, 1H-indol-3-il, hinolinil ili izohinolinil grupom, ili nerazgranatu C1-4-alkilarnino grupu koja je, u datom slučaju, supstituisana na atomu azota sa metil ili etil grupom, a koja je supstituisana u ω-položaju sa C5-7-cikloalkil grupom, sa fenil grupom koja može biti mono- ili disupstituisana sa atomima fluora, hlora ili broma, ili sa metil, nitro, metoksi, trifluorometil, hidroksi, amino ili acetilamino grupama, dok susptituenti mogu biti isti ili različiti, ili sa 2-pirolil, 3-pirolil, piridinil, lH-indol-3-il, hinolinil ili izohinolinil grupom, ili grupu formule u kojoj p označava broj 1 ili 2, o označava broj 2 ili, ukoliko Y1 i Y2 nisu jednovremeno atomi azota, on može takođe da označava broj 1, Y1 označava atom azota, ako R5 označava slobodan elektronski par, ili atom ugljenika, Y2 označava atom azota ili grupu >CH, R5 označava slobodan elektronski par, kada Y1 predstavlja atom azota, ili, kada Y1 predstavlja atom ugljenika, to je onda atom vodonika, alkil grupu sa 1 do 2 atoma ugljenika ili cijano ili fenil grupu, R6 označava atom vodonika ili, ukoliko Y1 nije atom azota, onda zajedno sa R5 jesu dodatna veza, R7 označava atom vodonika ili, ukoliko Y1 nije atom azota, a R5 i R6 zajedno predstavljaju dodatnu vezu, takođe zajedno sa RN to je 1,4-butadienilen grupu, RN označava atom vodonika ili alkil grupu sa 1 do 3 atoma ugljenika koja u ω-položaju može biti supstituisana sa jednom ili dve fenil ili piridinil grupe, pri čemu supstituenti mogu biti isti ili različiti, ili sa hidroksi ili metoksi grupom, fenil grupu, koja može biti mono- ili disupstituisana sa atomima fluora, hlora ili broma, ili sa metil grupama, nitro, metoksi, etoksi, trifluorometil, hidroksi ili cijano grupama, dok supstituenti mogu biti isti ili različiti, ili fenil grupu supstituisanu sa metilendioksi grupom, 2-piridinil ili 4-piridinil grupu, amino, benzoilamino, aminokarbonil, metilaminokarbonil, metoksikarbonil, etoksikarbonil, aminokarbonilamino, metilaminokarbonilamino, N-(aminokarbonil)-N-metilamino, N-(metilaminokarbonil)-N-metilamino, N-(aminokarbonil)-N-(4- fluorofenil)amino, N-(metilaminokarbonil)-N- fenilamino, fenilaminokarbonilamino, $N- fenil(metilamino)]karbonilamino, N- (fenilaminokarbonil)-N-metilamino, N- (fenilaminokarbonil)-N-fenilamino, benzoilaminokarbonilamino, N-(aminokarbonil)-N-fenilamino grupu ili fenilamino grupu, u datom slučaju, supstituisa
Patent YU-48947-B (YU)
Inventor: VOJISLAV ALIC DR
Filed: 1995-06-23
Abstract: Sistem za napajanje gorivom u gasovitom stanju motora sa unutrašnjim sagorevanjem, koji se sastoji od rezervoara (1) tečnog goriva cevnog voda (2) tečnog goriva, filtera (3) tečnog goriva, crpke (4), potisnog cevnog voda (5) tečnog goriva, naz načen time što je potisni cevni vod (5) tečnog goriva preko ekspanzionog ventila (6) cevnog voda (7) ekspandovanog tečnog goriva tangencijalnog priključka (8), centrifugalnog isparivača (9) tečnog goriva, izlazne cevi (10) i usisnih cevnih vodova (15,32) pare ekspandovanog goriva povezan sa vakuum crpkom (16) čiji je potisni cevni vod (17) komprimovane pare povezan sa cevnim vodim (27) smeše toplog vazduha i komprimovane pare goriva sa usisnom komorom motora sa unutrašnjim sagorevanjem pri čemu je ventilator (20) preko cevnog voda (21) vazduha, grejača vazduha (22) i cevnog voda (26) zagrejanog vazduha povezan sa navedenim potisnim cevnim vodom (17) komprimovane pare goriva i sa cevnim vodom (27) smeše toplog vazduha i komprimovane pare goriva. Prijava sadrži još 1 zavisan zahtev.
Patent AT-392331-B (AT)
Inventor: KLUSER REMO
IPC: E04B1/76
Filed: 1989-06-09
Granted: 1991-03-11
Abstract: PCT No. PCT/EP90/00854 Sec. 371 Date Apr. 3, 1991 Sec. 102(e) Date Apr. 3, 1991 PCT Filed May 28, 1990 PCT Pub. No. WO90/15206 PCT Pub. Date Dec. 13, 1990.A fastening assembly for securing insulating sheetings or boards to a solid base has a tubular extension secured to a large surface washer at the top end thereof, a nut securely held against rotation in the interior of the tubular extension and an elongated fastener inserted at its top end in to the tubular extension and locked by the nut and which is engaged at its lower end which has a bulge, in the solid base.
Patent AT-403189-B (AT)
Title: Rotor bearing
IPC: F16D1/06
Filed: 1994-09-26
Granted: 1997-11-25
Abstract: A rotor bearing for a rotor 21, which is connected to a drive shaft 17, 23, of a drive source, in particular for wind-power systems, has an outer ring 13 (which is connected to a fixed-position bearing) and an inner ring 14, between which roller bodies 15 are held. The inner ring 14 is connected, for example screwed, on one side to the rotor 21 and is connected on the other side to the drive shaft 17, 23, for example via a splined shaft connection 16. The outer ring 13 is screwed to the housing of a gearbox 22. This allows a not inconsiderable reduction in the weight and costs to be achieved for, for example, a wind power system. <IMAGE>
Patent DK-154469-B (DK)
Inventor: SCIKI KALMAN
IPC: B29D99/00
Filed: 1982-06-21
Abstract: PCT No. PCT/SE81/00283 Sec. 371 Date May 20, 1982 Sec. 102(e) Date May 20, 1982 PCT Filed Sep. 30, 1981 PCT Pub. No. WO82/01312 PCT Pub. Date Apr. 29, 1982.The ear plug (40) includes an elongate body with a rounded tip portion and of an elastic material enveloped by a deep-drawn sheath (41) of thin flexible plastics film material. Rearwardly the plug preferably has a neck portion from which the sheath projects in the form of a stiffer collar or flange. Production of the ear plug includes deep-drawing a thermoplastic film or foil into a sheath with desired thickness distribution, and filling the sheath with elastic material (53). Filling may take place simultaneously with deep-drawing, the body of elastic material constituting a die for deep-drawing in a forming hole (45), or after the deep-drawing. In the latter case, an elastic die body is used to advantage, the shape of which generally corresponds to that of the finished plug, for deep-drawing in a forming hole suited to the die body.
Patent DK-165727-B (DK)
Title: Means for fixing a joint prosthesis
Inventor: BRUCE LARS
IPC: A61F/
Filed: 1988-10-20
Abstract: Means for fixing a joint prosthesis the stem of which is provided with a friction surface (2). Said means comprises a substantially homogeneous mixture of a biologically compatible granular material in which the grains (3) have a substantially even particle size distribution and are substantially irregular and/or plastic. A method for fixing said joint prosthesis consists in that a cavity is reamed in the bone in which the prosthesis is to be applied, that grains (3) of biologically compatible material are applied in said cavity so as to form a grain bed, that the prosthesis is driven down into said grain bed until substantially the entire prosthesis stem is surrounded by the grains, that the grains are subjected to an external force, and that a device (5) for retaining the grains is applied on said bed around the prosthesis stem. <IMAGE>
Patent FI-70724-B (FI)
Inventor: LANE GEORGE ASHEL
IPC: C09K5/06
Filed: 1981-12-10
Granted: 1986-06-26
Abstract: A reversible liquid/solid phase change compositions comprising hydrated MgCl2 or Mg(NO3/MgCl2 and one or more of Ba(OH)2, Sr(OH)2, CaO, SrCO3, BaO, Ca(OH)2, Mg(OH)2, MgO, Na3AlF6 or CaC2O4, added to the compositions in an effective amount to suppress supercooling of the liquid phase of the compositions.
Patent FI-75518-B (FI)
Inventor: JANSSEN WILHELMUS GERARDUS ELI
IPC: B28C7/00
Filed: 1983-04-26
Granted: 1988-03-31
Abstract: A process and apparatus for the preparation of mortar from an aggregate and a binder is disclosed which comprises the use of a silo provided with at least one partition so as to create in the silo two or more compartments for the separate storage of the aggregate and the binder, the compartments being provided with conveyor screws, the speeds of which can be adjusted to control the volumetric flow of the components to a mixing chamber. A metering valve for water may also be connected to the mixing chamber. The silo compartment for the aggregate may be provided with a heating element to safeguard the mechanically operated slide valve against freezing. The conveyor screw in the outlet for the binder may be provided with a cam and a plunger rod with transverse projections to prevent arching in the compartment for the storage of the binder. The apparatus may be mounted on a truck to facilitate transport to the building site.
Patent FI-82455-B (FI)
Inventor: SUGIHARA HIROSADA
IPC: C07C69/738
Filed: 1984-04-19
Granted: 1990-11-30
Abstract: Novel condensed, seven-membered ring compounds of formula:wherein R' and R<sup>2</sup> each represent hydrogen, halogen, trif- fluoromethyl, lower alkyl or alkoxy, or both jointly form tri-or imethylene; R' is hydrogen, lower alkyl or aralkyl; R<sup>4</sup> is alogen or alkyl, aralkyl or cyclo-alkytalkyl which may be stituted; X is a group represented by the formula S(O)n ere n is an integer of 0 to 2); Y is a carboxyl group which be esterified or amidated; m is 1 or 2) and salts thereof. These compounds exhibit inhibitory activity on angioten- converting enzyme and so forth, and are of value as an it for diagnosis, prevention and treatment of hypertension.
Patent FI-81073-B (FI)
Inventor: LAGAS JAN ADOLF
IPC: C01B17/04
Filed: 1987-04-13
Granted: 1990-05-31
Abstract: The invention is directed to a process for the recovery of sulfur from a hydrogen sulfide containing gas, which comprises oxidizing hydrogen sulfide with oxygen, and then reacting the product gas of this oxidation further by using at least two catalytic stages, in accordance with the equation: 2H2S + SO2 2H2O + 3/n Sn. In order to improve the process and the process control, the invention is characterized in that the H2S concentration in the gas leaving the last catalytic stage (17) is controled (23) to have a value ranging between 0.8 and 3% by volume by reducing the quantitiy of combustion or oxidation air passed to the oxidation stage (2) and/or causing a portion of the hydrogen sulfide containing feedstock gas to bypass (25) the oxidation stage and to be added to the gas flowing to a catalytic stage.
Patent FI-96520-B (FI)
Inventor: IRIE YUKO
IPC: D21H21/02
Filed: 1989-12-11
Granted: 1996-03-29
Abstract: A process for preparing mechanical pulp and/or paper containing the mechanical pulp is described, wherein an acylglycerol lipase is used. The process according to the invention avoids the problems caused by the resins in the preparation of mechanical pulp and/or paper containing said pulp.