baber/WOPTO huggingface dataset:
Patent CA-2957286-A1 (CA)
Title: Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites
Inventor: NAVRATIL VACLAV
IPC: G01N33/58
Filed: 2015-08-04
Abstract: The invention provides a method for detection of active form of analytes in a sample and/or for determination of ability of tested substances to bind to the active site of these analytes, comprising the following steps: a) analyte or group of analytes from the sample is immobilized on the surface of a solid carrier either by non-specific non-covalent adsorption or by covalent binding of surface functional groups of the analyte and corresponding functional groups of the solid carrier, or preferably via a binding molecule which is bound to the surface of the solid carrier before immobilization of the analyte or group of analytes and is capable of selectively binding the analyte or group of analytes contained in the sample during incubation of the solid carrier with the sample; b) analyte or group of analytes is incubated with a detection probe which binds selectively to the analyte or group of analytes via a compound for selective binding to the analyte active site; whereas the probe consists of a low molecular compound for selective binding to the analyte active site; an oligonucleotide tag, optionally with a covalently attached fluorophore, biotin or a chemical group, and a chemical linker covalently linking the compound for selective binding to the analyte active site and the oligonucleotide tag; c) then the solid carrier is washed to remove unbound detection probe; and subsequently, the amount of bound detection probe is determined, whereas this amount is directly proportional to the amount of the analyte or group of analytes in the sample. The described method has broad application in medicine. Given the exceptional sensitivity of only a few dozen molecules, it provides the ability to determine the protein markers in blood in a concentration yet undetectable.
Patent CA-2958865-A1 (CA)
Title: Method and apparatus for drilling a wellbore for recovery of hydrocarbons from a hydrocarbon reservoir
Inventor: ADAMS STEWART A H
IPC: E21B47/09
Filed: 2017-02-22
Abstract: A method of drilling a wellbore for use in a hydrocarbon recovery operation, includes receiving signals from at least two gyroscopes coupled to a drill during drilling of the wellbore, the signals indicative of a change in orientation of the gyroscopes, analyzing the signals from the gyroscopes to identify a location of the drill relative to a previously identified location, comparing the location of the drill to a target location of the drill, and, in response to determining that the location of the drill differs from a target location, adjusting a direction of the drill based on the identified location of the drill, wherein drilling of the wellbore is continuous during receipt of the signals and analysis of the signals.
Patent CA-2960347-A1 (CA)
Inventor: PAN YUANLONG
IPC: A61P35/00
Filed: 2015-09-17
Abstract: The invention provides methods for the treatment of cancer, reduction of cancer risk, or prevention of cancer in a companion animal, comprising: identifying the companion animal having cancer or at risk for cancer and feeding a dietary formulation in a therapeutically effective amount to the animal. The dietary formulation can comprise 20% to 60% protein; 10% to 40% fat; 10% to 50% carbohydrates; and 0.01% to 5% alpha- amylase inhibitor, and optionally 1% to 50% resistant starch. The therapeutically effective amount can be effective for the treatment of cancer, the prevention of cancer, or the reduction of cancer risk in the companion animal by lowering the postprandial blood glucose of the companion animal as compared to the postprandial blood glucose of the companion animal ingesting a comparable dietary formulation that excludes the alpha- amylase inhibitor.
Patent CA-2962657-A1 (CA)
Title: Hybrid modular microwave heating system with separable cavities
Inventor: CHANG HONG-L
IPC: A21B2/00
Filed: 2017-03-27
Abstract: The present invention relates to a modular heating system comprising many composite heating modules, each with a microwave resonant cavity for accommodating an object. Each is separable into two parts. One part is a microwave heating semi-cavity which includes a microwave guiding device fixed on the machine frame, and the other part is a conductive heating semi-cavity which is transferrable as a carrier of heating object. The heat-receiving object is placed into a sealed container and positioned in the microwave resonant cavity. The microwaves propagated by the microwave guiding device can heat up the object. The sealed container is configured to sustain the outward expansion pressure due to the temperature rise in the object. The microwave resonant cavities act individually and do not affect each other, they are modular so as to provide the present invention with the flexibility to increase or decrease the module numbers for each production line.
Patent CA-2963763-A1 (CA)
Title: Buttons, beads, and removable clips bearing braille indicia for fabric
Inventor: JOVANOVIC ALEXA ROMA
IPC: A47G25/00
Filed: 2017-04-07
Abstract: A clip bearing Braille indicia removably attachable to fabric comprises a body member having a face bearing Braille indicia and a clipping member configured to removably clip the body member to the fabric with the Braille indicia facing outwardly. A button bearing Braille indicia for attachment to fabric includes a body having a face bearing Braille indicia and attachment means for facilitating attachment of the body of the button to the fabric with the Braille indicia facing outwardly. A bead bearing Braille indicia for attachment to an article using thread comprises a body having a face bearing Braille indicia and a passage, through the body beneath the face, for receiving the thread.
Patent CA-2966914-A1 (CA)
Inventor: WESNER JOHN CHRISTOPHER
IPC: B01F3/08
Filed: 2015-11-19
Abstract: The present invention generally relates to microparticles and, in particular, to systems and methods for encapsulation within microparticles. In one aspect, the present invention is generally directed to microparticles containing entities therein, where the entities contain an agent that can be released from the microparticles, e.g., via diffusion. In some cases, the agent may be released from the microparticles without disruption of the microparticles. The entities may be, for instance, polymeric particles, hydrogel particles, droplets of fluid, etc. The entities may be contained within a fluid that is, in turn, encapsulated within the microparticle. The agent may be released from the entity into the fluid, and then from the fluid through the microparticle. In such fashion, the release of agent from the microparticle may be controlled, e.g., over relatively long time scales. Other embodiments of the present invention are generally directed to methods of making such microparticles, methods of using such microparticles, microfluidic devices for making such microparticles, and the like.
Patent CA-2968188-A1 (CA)
Inventor: GORLIN MARC
IPC: G06Q10/08
Filed: 2015-10-13
Abstract: L'invention concerne un procédé, un appareil et une mémoire lisible par ordinateur permettant de mettre en uvre un service de livraison de paquets par applications à N niveaux. Des conducteurs peuvent s'enregistrer auprès du système et recevoir ensuite des alertes automatiques lorsque des points de ramassage (pour des tâches de livraison) se situent à proximité ou le long de leur trajet actuel de façon à ce que les conducteurs puissent gagner de l'argent supplémentaire en ramassant des paquets disponibles sur leur trajet actuel ou à proximité de celui-ci, et les livrer. Les modèles de conduite de chaque conducteur sont détectés, enregistrés et analysés de façon à pouvoir prédire automatiquement leurs destinations.
Patent CA-2968789-A1 (CA)
Inventor: BURGSTALLER CHRISTIAN
IPC: E21B43/12
Filed: 2016-02-02
Abstract: A method and an arrangement for operating an extraction of a fluid in a borehole are optimized. In deep-boring operations, the position of a depth level (13) is detected in the borehole (10). A measurement of the pressure is carried out at the head of the borehole (10). The pressure in the liquid below the depth level (13) in the borehole (10) is determined from the measured pressure at the head of the borehole (10) and from the ascertained position of the depth level (13). The determination of this pressure for regulating the performance of an extracting device (30) is used for the liquid to be extracted.
Patent CA-2971920-A1 (CA)
Title: Suppression du gene de la huntingtine induite par de l'arni
Inventor: KONSTANTINOVA PAVLINA STEFANOVA
IPC: C12N15/113
Filed: 2015-12-23
Abstract: La présente invention porte sur un ARN double brin comprenant une première séquence d'ARN et une seconde séquence d'ARN, les première et seconde séquences d'ARN étant pratiquement complémentaires, la première séquence d'ARN ayant une longueur de séquence d'au moins 19 nucléotides et étant pratiquement complémentaire à SEQ ID N° : 1. Ledit ARN double brin est destiné à être utilisé dans l'induction d'ARNi dirigé contre des séquences d'exon 1 du gène de l'huntingtine. L'ARN double brin selon l'invention permet de réduire la mort de cellules neuronales et les agrégats d'huntingtine dans un modèle animal.
Patent CA-2973037-A1 (CA)
Title: Procede integre de production d'hydrogene
Inventor: FOODY PATRICK J
IPC: C12N1/04
Filed: 2016-01-13
Abstract: La présente invention concerne un procédé intégré de production d'un produit de fermentation à partir de carbone fossile et de l'hydrogène présent dans un flux de gaz de purge résultant d'un procédé de production d'hydrogène. Selon un mode de réalisation de l'invention, un flux de gaz de purge obtenu à partir d'un procédé de production d'hydrogène est fermenté par des microorganismes dans un ou plusieurs bioréacteurs pour produire le produit de fermentation. Un flux de gaz d'échappement de fermentation provenant d'un ou de plusieurs bioréacteurs comprenant de l'hydrogène, du monoxyde de carbone et/ou du méthane est ensuite obtenu et de la chaleur est générée à partir de ce dernier pour fournir de l'énergie pour le procédé de production d'hydrogène.
Patent CA-2973407-A1 (CA)
Inventor: PEARCE CODY A
IPC: E21B10/573
Filed: 2016-01-12
Abstract: Drilling tools, such as drill bits, having a shank, a crown, and a plurality of abrasive cutting elements. In the case of impregnated drilling tools, the abrasive cutting elements are dispersed throughout at least a portion of the crown. In the case of surface-set drilling tools, the abrasive cutting media is secured to and projects from a cutting face of the crown. The matrix of the crown of the drilling tools includes a carbide-forming alloy that forms a direct carbide bond with at least one cutting element of the plurality of abrasive cutting elements.
Patent CA-2975368-A1 (CA)
Inventor: HASHIMOTO Miku
IPC: B65D75/62
Filed: 2016-01-20
Abstract: The purpose of this invention is to provide peel-open packaging and an opening structure for peel-open packaging wherein a portion in a peeling region where an internal member and an external member are peelably attached can be easily and simply peeled open and content sealed in the packaging can be smoothly removed from the portion that has been peeled open from both members. A cover (13) for peel-open packaging (10A) comprises a sheet member (20) disposed on a side corresponding to an accommodating portion (14) of a packaging body (11) and a film member (30) bonded to the front surface side of the sheet member (20). Cuts (21), (31) passing through the members (20), (30) in the thickness direction (T) are disposed to intersect with the longitudinal direction L in a peeling region (16) that is set in a bent portion (15) of the members (20), (30) and to be separated a prescribed distance in the longitudinal direction (L). Opposing faces in the peeling region (16) that correspond to the area between the cuts (21), (31) in the members (20), (30) are peelably attached by way of an adhesion layer (N1).
Patent CA-2977549-A1 (CA)
Inventor: NICHOL SCOTT
IPC: C01F7/441
Filed: 2016-02-12
Abstract: A method comprising (a) reacting aluminum metal with an acid in the presence of water to provide a first aluminum salt solution comprising an aluminum salt in water, wherein the aluminum salt comprises a reaction product of the acid and the aluminum metal, (b) heating the first aluminum salt solution to provide a mother liquor and solid aluminum salt, (c) optionally, separating the solid aluminum salt from the mother liquor, (d) optionally, dissolving at least a portion of the separated solid aluminum salt with water to provide a second aluminum salt solution, (e) spray roasting the first, or second (if produced), aluminum salt solution to provide an aluminum oxide powder, and (f) washing the aluminum oxide powder, wherein the washed aluminum oxide powder comprises less than about 30 ppmw total metallic and alkyl impurities.
Patent CA-2978607-A1 (CA)
Inventor: WICKSTROM KURTIS H
IPC: C05G3/60
Filed: 2016-03-07
Abstract: Enhancement of crop yields through the application of sugars, for example, monosaccharides, and/or disacchandes and/or polysaccharides, to soil. Application of the sugars is at a rate of at least 25 pounds per acre, more preferably at least 50 pounds per acre, and more preferably at rates of between 100-250 pounds per acre or more regardless of a solid or liquid application. The application involves at least one application of the sugars at a time prior to, during and/or after planting. Depending on the form and/or type of the sugars applied, application can be accomplished via broadcast spreading for solids or via spraying for liquids. The sugar can be sucrose supplied in the form of granulated sucrose and broadcast spread prior to planting. The sugar can be applied in-furrow either separately, or in combination with a conventional fertilizer.
Patent CA-2978998-A1 (CA)
Inventor: KAWAMURA MIZUHO
IPC: G01N33/53
Filed: 2010-10-27
Abstract: Methods and kits for measuring a component to be measured in a specimen are provided, which enable accurate measurements that are not affected by reaction temperatures or such when measuring the component to be measured, such as antigens. Methods for measuring a component to be measured, which comprise: reacting, in the presence of a fatty acid alkanolamide, a component to be measured in a specimen with a first antibody which binds to the component to be measured; then reacting a labeled second antibody, in which a label is bound to a second antibody that binds to the component to be measured, to form an immunocomplex comprising the first antibody, the component to be measured, and the labeled second antibody; and measuring the amount of the label in the formed immunocomplex; and kits for measuring the component to be measured in a specimen used in the measurement methods.
Patent CA-2979273-A1 (CA)
Title: Short fatty acid tail polymyxin derivatives and uses thereof
Inventor: VAARA MARTTI
IPC: C12Q1/18
Filed: 2009-02-05
Abstract: A method for developing an antibiotic is disclosed. The method comprises the steps of:  a) providing a natural polymyxin or octapeptin compound, or a derivative thereof, having a total of 4 to 6 positive charges and a terminal moiety (D) comprising a total of 1 to 5 carbon atoms; b) replacing from 1 to 3 residues carrying one or more positive charges with a residue not having a positive charge, or with a covalent bond, thereby generating a derivative of a polymyxin compound having 3 positive charges and a terminal moiety (D) comprising a total of 1 to 5 carbon atoms; c) assaying said polymyxin derivative for the ability to sensitize Gram-negative bacteria to an antibacterial agent; and d) selecting compounds having the ability to sensitize Gram-negative bacteria to an anti-bacterial agent.
Patent CA-2982367-A1 (CA)
Inventor: BEAUMONT DARCY L
IPC: F16L58/00
Filed: 2017-10-16
Abstract: A layered gasket consisting of two gaskets joined together to make a single gasket consisting of an inside diameter that matches that of coated or lined piping systems. The gasket measures erosion in multiple locations around the inside circumference of the coated or lined piping system. Monitoring locations can include the six O  Clock, twelve O  clock, three O clock, nine O clock or areas between these locations. The gasket is highly effective when monitoring erosion in piping systems that are rotated.
Patent CA-2982429-A1 (CA)
Inventor: ARTEMYEV NIKOLAY
IPC: G06Q30/02
Filed: 2016-04-14
Abstract: Methods, apparatus and systems are presented that provide a user interface to a user terminal. User interfaces are provided upon electromagnetic interrogation of one or more interrogatable data storages. A method is presented that bases a second user interface, that is different to a first user interface associated with first data, upon second data and data associated with the receiving of the first data.  A method is presented that provides a user interface configured to initiate user access to a first interactive session with a program. A  method is presented for outputting data from a user terminal a remote computer system upon electromagnetic interrogation of a data storage by a user terminal. A packaging for a smoking article is also presented.
Patent CA-2982639-A1 (CA)
Inventor: ALLARD LUDOVIC
IPC: A61M39/22
Filed: 2016-04-15
Abstract: This medical valve (1) comprises a body (2) provided with three female connectors (5a, 5b, 5c) and a male connector (6), at least one (5c) of the female connectors (5a, 5b, 5c) being designed to receive an injection syringe, and a mobile plug (3), which is mounted in the body (2), is provided with a rotation lever and comprises a fluid circulation channel. The female connector (5c) designed to receive an injection syringe comprises an indexing means in order to prevent a mixing syringe from being mounted on this connector (5c). The invention also relates to a kit for preparing a product to be injected, said kit comprising such a medical valve (1). The invention also relates to a method for preparing a mixture or an emulsion which is intended to be injected into a patient with the aid of such a medical valve (1).
Patent CA-2989573-A1 (CA)
Title: Purification et mesure de la methylation de l'adn integrees et co-mesure des mutations et/ou des niveaux d'expression de l'arnm dans une cartouche de reaction automatisee
Inventor: LAI EDWIN W
IPC: B01L3/00
Filed: 2016-06-14
Abstract: Dans divers modes de réalisation, la présente invention concerne des procédés de détermination de la méthylation de l'ADN. Dans un mode de réalisation représentatif, mais non limitatif, le procédé comprend i) la mise en contact d'un échantillon biologique comprenant un acide nucléique avec un premier matériau de matrice comprenant une première colonne ou un premier filtre, ledit matériau de matrice se liant aux, et/ou filtrant, les acides nucléiques dans ledit échantillon et purifiant ainsi l'ADN; ii) l'élution de l'ADN lié adsorbé sur le premier matériau de matrice et la dénaturation de l'ADN pour obtenir un ADN élué dénaturé; iii) le chauffage de l'ADN élué en présence d'ions bisulfite pour obtenir un acide nucléique désaminé; iv) la mise en contact dudit acide nucléique désaminé avec un second matériau de matrice comprenant une seconde colonne pour lier ledit acide nucléique désaminé audit second matériau de matrice; v) la désulfonation de l'acide nucléique désaminé et/ou l'élution et la désulfonation simultanées de l'acide nucléique par mise en contact de l'acide nucléique désaminé avec une solution alcaline pour obtenir un acide nucléique converti par le bisulfite; vi) l'élution dudit acide nucléique converti par le bisulfite adsorbé sur ledit second matériau de matrice; et vii) la mise en uvre d'une PCR spécifique de la méthylation et/ou du séquençage de l'acide nucléique, et/ou d'une analyse des courbes de fusion à haute résolution (HRM) dudit acide nucléique converti par le bisulfite pour déterminer la méthylation de l'acide nucléique, les étapes iv) à vi) au moins étant mises en uvre dans une cartouche de réaction unique.
Patent CA-2993771-A1 (CA)
Title: High a1-content vibration-damping ferritic stainless steel material, and production method
Inventor: HORI YOSHIAKI
IPC: C22C38/52
Filed: 2016-08-10
Abstract: Provided is a ferritic stainless steel material exhibiting excellent vibration-damping properties. This vibration-damping ferritic stainless steel material has a chemical composition which includes, expressed in mass%, 0.001-0.04% of C, 0.1-2.0% of Si, 0.1-1.0% of Mn, 0.01-0.6% of Ni, 10.5-20.0% of Cr, 0.5-5.0% of Al, 0.001-0.03% of N, 0-0.8% of Nb, 0-0.5% of Ti, 0-0.3% of Cu, 0-0.3% of Mo, 0-0.3% of V, 0-0.3% of Zr, 0-0.6% of Co, 0-0.1% of rare earth elements (REM), and 0-0.1% of Ca, the remainder being Fe and unavoidable impurities. The vibration-damping ferritic stainless steel material has a metallographic structure in which the matrix is a ferrite single phase, and the average crystal grain size of ferrite crystal grains is 0.3-3.0 mm. The vibration-damping ferritic stainless steel material has a residual magnetic flux density of not more than 45 mT.
Patent CA-2995325-A1 (CA)
Inventor: SAITOH FUMIHIKO
IPC: A61K31/496
Filed: 2016-08-10
Abstract: The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof or a solvate of these. The present invention provides a compound having Nrf2 activation ability.
Patent CA-2995359-A1 (CA)
Inventor: SMITH ROGER P
IPC: G06Q10/08
Filed: 2016-08-04
Abstract: A method for tracking containers. The method includes manufacturing containers (24), including forming the containers (24) and serializing them with machine-readable codes (26). The method further includes using the machine-readable codes (26) to store data associated with the containers (24), and supplying the containers (24) to a customer. The method still further comprises receiving from the customer, data obtained from customer-readings of the machine- readable codes (26); and receiving from one or more other locations in a distribution chain in which the containers (24) travel, data obtained from readings of the machine-readable codes (26) at those locations. The method still further comprises comparing the data from the customer-readings and other readings of the machine-readable codes (26) across product brands, product distribution channels, and/or container types, and providing the data to the customer. In at least some embodiments, the method further comprises receiving from the customer a compensation for the containers (24), for example, a per-refill compensation.
Patent CA-2998342-A1 (CA)
Inventor: MEIER OLIVER C
IPC: B64D47/00
Filed: 2018-03-16
Abstract: A system and method for the real-time optimization of aircraft fuel economy is disclosed. Sensors are provided to monitor in-flight performance characteristics, to monitor the status of aircraft control elements during flight, to monitor fuel consumption, and to identify aircraft position information during flight. A processor is coupled to receive information from the sensors. During flight, the processor calculates a current performance level by entering the received information into a predetermined flight model. The processor then determines, based on a comparison of the calculated current performance level with a predetermined expected performance level, a current level of fuel efficiency. Next, the processor determines any parameter changes for improving fuel efficiency. Finally, the processor causes the determined parameter changes to be displayed on a flight deck display. The flight crew may then selectively implement one or more of the determined parameter changes via the flight deck display.