Patent SG-11201810524Y-A (SG)
Title: Injection device for subretinal delivery of therapeutic agent
Inventor: PRICE DANIEL W
IPC: A61F9/00
Filed: 2017-06-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 11111110111101110111111111111111111111111111111111H1111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2017/218615 Al 21 December 2017 (21.12.2017) WIP0 I PCT (51) International Patent Classification: James G.; 4545 Creek Road, Cincinnati, Ohio 45242 (US). A61F 9/00 (2006.01) A61M 25/02 (2006.01) DENLINGER, Clinton; 4545 Creek Road, Cincinnati, Ohio 45242 (US). PRENGER, Daniel J.; 10255 Even- (21) International Application Number: PCT/US2017/037368 dale Commons Drive, Cincinnati, Ohio 45241 (US). KING, Geoffrey; 10255 Evendale Commons Drive, Cincinnati, (22) International Filing Date: Ohio 45241 (US). UHLAND, Scott; 2389 Lincoln Village 14 June 2017 (14.06.2017) Drive, San Jose, California 95125 (US). TSAI, Mark C.; 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 (25) Filing Language: English (US). KEANE, Michael F.; 800/850 Ridgeview Drive, (26) Publication Language: English Horsham, Ohio 19044 (US). KHAN, Isaac J.; 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 (US). KO, (30) Priority Data: Benjamin L.; 205 West 4th Street, Suite 1140, Cincinnati, 62/351,628 17 June 2016 (17.06.2016) US Ohio 45202 (US). MEYER, Thomas E.; 205 West 4th 15/609,457 31 May 2017 (31.05.2017) US Street, Suite 1140, Cincinnati, Ohio 45202 (US). TURN- (71) Applicant: JANSSEN BIOTECH, INC. [US/US]; ER, Denis P.; 1633 Via Tulipan, San Clemente, California 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 92673 (US). (US). (74) Agent: SHIRTZ, Joseph F. et al.; Johnson & Johnson, (72) Inventors: PRICE, Daniel W.; 4545 Creek Road, Cincin- One Johnson & Johnson Plaza, New Brunswick, New Jer- nati, Ohio 45242 (US). OBERKIRCHER, Brendan J.; sey 08933 (US). 4545 Creek Road, Cincinnati, Ohio 45242 (US). LEE, = (54) Title: INJECTION DEVICE FOR SUBRETINAL DELIVERY OF THERAPEUTIC AGENT 1 = 30 —,-.-- ----:- . = 24 40 = 20 = = = 1 = = 24 = = ) = = = ,-, Fi g . 1 ir) Il GO (57) : An apparatus includes a pad assembly (460), an injector assembly (700), an injector driver (600), and a fluid source. 1-1 The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible ei ---- cannula (702), and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted IN through an incision in an eye (301) of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive © the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle. ei C [Continued on next page] WO 2017/218615 Al MIDEDIMOMOIDEIRMEM00111111111111111111110111110111111111111 (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))