baber/WOPTO huggingface dataset:
Patent NZ-262352-A (NZ)
Title: Polypeptide isolated from rat serum that exhibits bone stimulatory activity, coding sequences, production and use
Inventor: TAM CHERK SHING
IPC: C12P21/08
Filed: 1994-03-14
Abstract: A polypeptide substance isolated from rat serum which, upon administration to rats incapable of producing PTH (parathyroidectomized rats), produces an increase in the observed bone mineral apposition rate. The substance has been isolated in two forms, a first larger polypeptide having a molecular weight about twice that of a second smaller polypeptide. The first eleven amino acids of the sequence of the smaller polypeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu Thr Lys Pro Ile. The first seven amino acids of the larger polypeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu. The larger polypeptide might be the dimer of the smaller peptide. A nucleic acid probe, based on the amino acid sequence of the rat peptide was used to screen a human liver cDNA fetal library. A polypeptide was thus chemically synthesized according to the sequence Gly Ile Gly Lys Arg Thr Asn Glu His Thr Ala Asp Cys Lys Ile Lys Pro Asn Thr Leu His Lys Lys Ala Ala Glu Thr Leu Met Val Leu Asp Gln Asn Gln Pro. The bone apposition rate in rats increases in a dose dependent fashion upon administration of this chemically synthesized compound.
Patent NZ-279392-A (NZ)
Title: Isothiazolidin-3-one-1,1-dioxide and 3-oxo-1,2,5-thiadiazolidine-1,1-dioxide derivatives
Inventor: GROUTAS WILLIAM C
IPC: A61K31/41
Filed: 1995-01-03
Abstract: Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
Patent NZ-299099-A (NZ)
Title: Sterilizing surfaces using a mixture of air and vaporised hydrogen peroxide
Inventor: METZGER ULRICH
IPC: A61L2/20
Filed: 1996-07-31
Abstract: The apparatus for continuously sterilising surfaces in an aseptic filling line, comprises a feeding tube (10) for feeding a mixture of hot air and vaporised hydrogen peroxide and a plurality of nozzles (8) through which said mixture is introduced on the surfaces (9) to be sterilised, wherein the feeding tube (10) includes a section formed by a porous tube (4) for feeding directly the gaseous hydrogen peroxide (1) into the stream of hot air, said porous tube (4) being surrounded by a heated means (3). <IMAGE>
Patent NZ-315642-A (NZ)
Title: Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same
Inventor: JESCHKE PETER
IPC: C07D295/215
Filed: 1996-07-30
Abstract: he present invention relates to the use of didepsipeptides of the formula 1 for the control of endoparasites where: R1 is H, straight chain or branched alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl, heteroarylalkyl, each of which is optionally substituted R1 and R2 together with the atoms to which they are bonded represent a 5-or 6-membered ring which can be optionally substituted by O, S, sulphoxyl or sulphonyl and is optionally substituted, R2  and R3 independently of one another represent H, straight chain or branched alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl, heteroarylalkyl, alkenyl, cycloalkylalkyl, each of which is optionally substituted or R2 and R3 together is a spirocyclic ring optionally substituted, R4 and R5 independently of one another represent H, straight chain or branched alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl, heteroarylalkyl, alkenyl, cycloalkylalkyl, each of which is optionally substituted or R4 and R5 together is a spirocyclic ring optionally substituted A is H, alkyl, aralkyl, formyl, alkoxydicarbonyl or a radical G1 where the substituents are disclosed in the specification.
Patent NZ-329125-A (NZ)
Title: Exercising apparatus for the feet and legs, footrests attached to rocking beam
Inventor: DE GIORGIS FREDERICK CHARLES
IPC: A63B22/18
Filed: 1997-11-07
Abstract: The invention as shown in FIG. 5 is an exercising device to enable a person to exercise his or her feet while seated. More particularly, the exercising device enables a person to simulate a walking action while seated. The exercising device has a base 1 a pivot beam 5, and two footrests 8. Rear parts of the footrests 8 can pivot with respect to the base 1 by way of ball and socket fittings, and forward parts of the footrests 8 can pivot with respect to the pivot beam 5 by way of additional ball and socket fittings. The pivot beam 5 can pivot with respect to the base 1 by way of a further ball and socket fitting. When the exercising device is in use the person can place his or her feet on the footrests and tilt both the feet and footrests from side to side. The person can also cause forward parts of the footrests 8 to move up and down alternately by way of the pivot beam 5 by alternately pushing his or her feet down against the footrests.
Patent NZ-331323-A (NZ)
Title: Adaptive frequency allocation in a telecommunication system
Inventor: KARLSSON AKE
IPC: H04W16/04
Filed: 1997-02-24
Abstract: In a telecommunications network, a method and apparatus for allocating frequency channels makes uplink and downlink signal quality measurements for channels that are in use or available for use and for channels that may become available for use.  The measured uplink and downlink signal quality is compared for each of the channels. Already selected channels (i.e., channels in use or available for use) that exhibit poor signal quality characteristics because the measured downlink signal quality is less that a first predefined amount and the is also less than the measured uplink signal quality by a second predefined amount, are exchanged with candidate channels (i.e., channels that may become available for use) that exhibit better signal quality characteristics to thereby improve the overall signal quality of the network.
Patent NZ-503980-A (NZ)
Title: 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (= gabapentin analogues), pharmaceuticals thereof, and their use in the treatment of neurological disorders
Inventor: BRYANS JUSTIN STEPHEN
IPC: C07C/
Filed: 1998-11-10
Abstract: Compounds of formula ID or IE, wherein: n is 0 to 2. R is sulfonamide, amide, phosphonic acid, heterocycle, sulfonic acid or hydroxamic acid. X is -O-, -S-, -S(O)-, -S(O)2 or NR'1 wherein R'1 is H, alkyl, benzyl, -C(O)R'2 wherein R'2 is alkyl, benzyl or phenyl or -CO2R'3 wherein R'3 is alkyl, or benzyl wherein the benzyl or phenyl groups can be unsubstituted or substituted by 1 to 3 substituents selected from halogen, trifluroromethyl, and nitro. With the proviso that when X is NR'1 and R'1 is benzyl, R cannot be morpholino or piperidino. Also described is a pharmaceutical composition that comprises the compound of formula ID or IE. The compounds of formulae ID and IE are useful for treating epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders and gastrointestinal damage.
Patent NZ-509606-A (NZ)
Title: Information security analysis system
Inventor: MALONEY MICHAEL P
IPC: G06F9/45
Filed: 1999-07-20
Abstract: A method of detecting virus computer code, analyzing computer source and/or executable code, dynamic monitoring data communication networks and 3-d visualizing and animating data comprises: a) collecting or gathering information on the network such as the types of computer source code and/or executable code or the structure and operation of the network and network users; b) generating a knowledge base of the information gathered; c) parsing the information in the generated knowledge base to generate data in selected categories in readable format and d) analyzing and visualizing data in the selected categories.  If the information gathered relates to the types of computer code then step d) includes analyzing the data in the selected categories to create functional alteration between two or more similar codes for computer programs and visualizing the analyzed data for comparison of two or more similar codes for computer programs to determine the degree of functional alteration. If the information gathered relates to the structure and operation of the network and network users then step d) includes analyzing the data in the selected categories for preparation of visualizing diagrams and displaying the analyzed data for graphical analysis of the gathered information for animation of network traffic and structure. The software used, not including the computer operating systems, is a combination of sensor, analysis, data conversion, and visualization programs. The hardware platforms consist of several different types of interconnected computers, which share the software programs, data files, and visualization programs via a Local Area Network (LAN).  This collection and integration of software and the migration to a single computer platform results in an approach to LAN/WAN monitoring in either a passive and/or active mode. The architecture permits digital data input from external sensors for analysis, display and correlation with data and displays derived from the four major software concept groups.
Patent NZ-511152-A (NZ)
Title: Chelated feed additive and method of preparation
Inventor: CIRIBOLLA ANTONIO
IPC: A23K1/175
Filed: 1999-07-19
Abstract: Additive for agro-zootechnical use and in particular for alimentary use in the zootechnical sector, consisting of a chelate produced by combination of an organic molecule with a metal, characterised in that ti is represented by the formula (CH3SCH2CH2CHOHCO)2M - nH2O, wherein M is a bivalent metal in the form of a carbonate salt.
Patent NZ-517798-A (NZ)
Title: Improved toxicity screening method
Inventor: MCKIM JAMES M
IPC: G01N33/50
Filed: 2000-09-14
Abstract: A method of predicting the in vivo cytotoxicity of a chemical compound comprising: (a) culturing cells in culture medium that comprises a plurality of concentrations of the chemical compound, (b) measuring a first indicator of cell health at four or more concentrations of the chemical compound, (c) measuring a second indicator of cell health at four or more concentrations of the chemical compound, (d) measuring a third indicator of cell health at four or more concentrations of the chemical compound, (e) predicting a toxic concentration (Ctox) of the chemical compound from the measurements of steps (b), (c) and (d) wherein the predicting comprises: (i) performing dose response analyses of measurements from steps (b), (c) and (d); (ii) identifying from the dose response analyses the highest concentration of the chemical compound at which a measurable toxic effect of the chemical compound is not observable (NOEL) in any dose response analyses of step (i); (iii) selecting as Ctox a concentration less than or equal to the concentration identified in step (ii).
Patent NZ-518239-A (NZ)
Title: Device and method for cleaning a filter
Inventor: VAN DER ZEE JAN
IPC: B01D46/04
Filed: 2000-10-19
Abstract: A device for cleaning a filter, comprising a container (1)  in which a gas pressure can be built up. The wall  (17) of  the  container  (1)  includes a first  opening,  through which  a  discharge pipe extends into the  container,  which discharge  pipe is provided with a circular valve seat  (21) at  its end, and a second opening, through which the housing (13) of a valve member (14) extends into the container.  The valve  member  (14) is cylindrical in shape, at  least  near valve  seat  (21).  The  valve seat  (21)  is  connected  to housing (13).
Patent NZ-519806-A (NZ)
Title: Receiving device and repeating device
Inventor: YABE TOSHIYASU
IPC: G06F17/30
Filed: 2001-11-27
Abstract: A terminal that records references to points of communication, contained in an object, and communicates selectively to a point of communication referenced by a recorded reference comprises: a receiver that receives an object which contains at least one reference to a point of communication, the reference is of a type selected from at least a telephone number, an e-mail address or a uniform resource locator; a reference locator that extracts the reference from the received object and stores the extracted reference in a memory; a selector that reads out the reference stored in the memory; multiple communication functionalities selectively activated according to a type of reference in order to communicate to a point of communication referenced by the reference; and a communication control that automatically reconfigures the terminal to communicate to a point of communication referenced by the read-out reference, using at least one of the multiple communication functionalities conforming to the type of the read-out reference.
Patent NZ-522083-A (NZ)
Title: Oxidation process for preparing the intermediate 6.Alpha.,9.Alpha.-difluoro-11.beta.,17.alpha.-dihydroxy-16.alpha.-methyl-androst-1,4-dien-3-one17.beta.-carboxylic acid, used in the preparation of anti-inflammatory steroids
Inventor: COOTE STEVEN JOHN
IPC: C07J31/00
Filed: 2001-07-20
Abstract: Oxidation process for preparing the intermediates of formula (I) such as 6a.,9a.-difluoro-11b.,17a.-dihydroxy-16a.-methyl-androst-1,4-dien-3-one17b.-carboxylic acid, which are useful in the preparation of anti-inflammatory steroids is disclosed, wherein the process comprises the step represented by the reaction shown herein, wherein step (a) comprises oxidation of a solution containing compound of formula (II) wherein the solution is formed in a mixture of water and tetrahydrofuran.
Patent NZ-522659-A (NZ)
Title: Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol or its prodrug in the treatment of symptoms of dementia and dopamine induced psychosis
Inventor: SCHEYER RICHARD
IPC: A61K31/445
Filed: 2001-05-23
Abstract: The use of (+)-alpha -(2,3-dimethoxylphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol or a pharmaceutically acceptable salt thereof; or a prodrug, its stereoisomer or pharmaceutically acceptable salt thereof for the preparation of a pharmaceutical composition useful in the treatment of the behavioural, psychological or motor symptoms of dementia, such as Lewy Body dementia, Alzheimer's Disease or Parkinson's Disease, wherein the prodrug is of Formula II wherein R is C1-C2 alkyl.
Patent NZ-523550-A (NZ)
Title: Lipid-rich plaque inhibitors
Inventor: TERASHITA ZEN-ICHI
IPC: A61K31/5377
Filed: 2001-07-13
Abstract: Lipid-rich plaque inhibitors containing compounds of formula (I) or salts thereof are disclosed, wherein: A is a cyclic hydrocarbon or the like; B is a heterocycle or the like; X and Y are each NR1- (wherein R1 is hydrocarbyl or the like) or the like; D is C1-3 alkylene or the like; E is NH- or the like; G is a free valency or the like; and Ar is aryl or the like, or alternatively D or R4, together with constituent atoms of B, may form a ring. A detailed definition of these variables is given in the specification.
Patent NZ-524924-A (NZ)
Title: Methods for preparing human thrombopoietin polypeptides by mammalian cell cultures
Inventor: CAYOTA GUZICOVSKY ALFONSO
IPC: C12N15/09
Filed: 2001-08-23
Abstract: An expression vector replicable in mammalian cells contains: i) a hTPO transcription portion consisting of: a) a transcription promoter derived from a variable kappa gene of human immunoglobulins; b) a DNA segment encoding the complete hTPO polypeptide including its signal peptide; c) an immunoglobulin transcription enhancer DNA segment of the human kappa gene; d) a transcription terminator; and e) a polyadenylation signal (ii) a gene encoding resistance to the antibiotic neomicyn type drugs (iii) a gene encoding resistance to the antibiotic ampicillin; and (iv) a replication origin for E Coli ColEl ori. The vector allows biologically active human thrombopoietin to be obtained from in vitro cultures of mammalian cells. Preferably the TPO is obtained from a cultured cell line derived from the murine myeloma X-63 (ATCC: P3X63Ag8.6533, CRL 1580).
Patent NZ-527615-A (NZ)
Title: Method of synthesizing camptothecin-relating compounds
Inventor: OGAWA TAKANORI
IPC: C07C205/45
Filed: 2002-02-21
Abstract: The present invention is to prepare efficiently 2'-amino-5'-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis, which is a starting material for irinotecan hydrochloride and various kinds of camptothecin derivatives, and to provide stably CPT and its derivatives.
Patent NZ-529016-A (NZ)
Title: Waterproof building timber
Inventor: YOUNG WAYNE
IPC: E04B1/76
Filed: 2003-10-21
Abstract: A set of at least two building material items of which one item is a timber with grooves and a waterproof membrane surrounding the timber to prevent or manage any water ingress with a self draining capillary action assisting through the grooves.
Patent NZ-539137-A (NZ)
Title: Therapeutic treatment
Inventor: BOYLE FRANCIS THOMAS
IPC: A61K45/06
Filed: 2003-10-07
Abstract: Disclosed is a combination comprising the endothelin receptor antagonist ZD4054, or a pharmaceutically acceptable salt thereof, and an EGFR TKI, or a pharmaceutically acceptable salt thereof.
Patent NZ-539242-A (NZ)
Title: Methods of generating and screening for proteases with altered specificity
Inventor: NGUYEN JACK
IPC: C12N9/64
Filed: 2003-10-02
Abstract: Disclosed is a method of producing candidate therapeutics that cleave a substrate sequence in a target protein that is associated with or that causes a disease or pathology, the method comprising: producing a library of proteases and/or catalytically active portions thereof, wherein each member of the library comprises a mutation or mutations in a scaffold protease or a catalytically active portion thereof; contacting each member of the library with a composition containing the target protein or a portion thereof containing the substrate sequence; measuring the activity of each members of the library in cleaving the substrate sequence in the target protein; and based on the measured activity and/or specificity, identifying and selecting those members of the library that have an increased cleavage activity and/or specificity for the substrate sequence, thereby identifying a modified protease(s) or a catalytically active portion thereof that modulates the activity of a target protein that is involved with or causes a disease or pathology, whereby the identified protease(s) are candidate therapeutics for treatment the disease or pathology.
Patent NZ-542066-A (NZ)
Title: Medical instruction system
Inventor: OOSTHUIZEN GEORGE VALENTINE EA
Filed: 2005-08-29
Abstract: A system for providing instruction or training regarding the conduct of a procedure or use of a device is disclosed. The system comprises a display providing the user with a multimedia presentation including the components: (a) Anatomical information relating to the procedure or relevant to the use of the device; (b) Text instructions relating to the conduct of the procedure or use of the device and (c) A narrated video clip showing the conduct of the procedure or use of the device. The user is able to interact with the presentation to select and manipulate selected instruments with a computer interface device and conduct the procedure or use the device in a virtual environment.
Patent NZ-543273-A (NZ)
Title: Chuck
Inventor: HARRIS DAVID
IPC: B23B31/12
Filed: 2004-03-24
Abstract: A chuck with a central body for including a nose section (6) and a tail section (8) is disclosed. A number of passageways (12) are angled with respect to the axis of rotation of the central body. Jaws (14) may move through the passageways (12) in response to rotation of a rotatable nut (20) which is in threaded engagement with the jaws (14). A bearing member (36) consisting of a resiliently deformable ring sits in a tapered portion between the central body and the nut (20) so that radial displacement of the bearing (36) causes the chuck to be locked against release.
Patent NZ-543316-A (NZ)
Title: Soft handoff with interference cancellation in a wireless frequency hopping communication system
Inventor: AGRAWAL AVNEESH
IPC: H04W72/08
Filed: 2004-05-07
Abstract: A method and apparatus for receiving data transmission in a wireless frequency hopping (FH) communication system are disclosed. The apparatus comprises: means for obtaining received symbols for a plurality of subbands; means for processing the received symbols to obtain decoded data for each of at least one primary terminal, wherein the at least one primary terminal is assigned at least one primary FH sequence to use for data transmission, and wherein the at least one primary FH sequence is orthogonal to at least one other primary FH sequence; means for estimating interference due to the at least one primary terminal; means for cancelling the interference due to the at least one primary terminal from the received symbols to obtain interference-cancelled symbols; and means for processing the interference-cancelled symbols to obtain decoded data for each of at least one secondary terminal, wherein the at least one secondary terminal is assigned at least one secondary FH sequence to use for data transmission, and wherein the at least one secondary FH sequence is not orthogonal to the at least one primary FH sequence.
Patent NZ-543904-A (NZ)
Title: Treatment of wood based on novel formulations of boratranes
Inventor: HAYWARD PETER JAMES
Filed: 2005-12-02
Abstract: Disclosed is a wood preservative composition comprising leach resistant boron in the form of a boratrane, and a synergistic proportion of quaternary ammonium compound. The composition can include triadimefon in synergistic proportions with the boratrane and quaternary ammonium compound. It can be in the form of a stable water dilutable composition and include an insoluble fungicide or an insecticide. The composition has the property of providing decay and insect resistance to wood, reconstituted wood fibers and flake and veneer products.
Patent NZ-545723-A (NZ)
Title: Method for delivering products for human consumption
Inventor: OSTRO MAURICE
IPC: G06Q10/08
Filed: 2001-07-24
Abstract: Products for consumption by aircraft passengers are packed into meal trays at a manufacturing centre and transported in bulk to a distribution centre, where predetermined numbers of the trays are individually stacked into trolleys for distribution to the aircraft in accordance with the number of meals ordered for the flight.
Patent NZ-551004-A (NZ)
Title: Neurologically-active compounds
Inventor: KOK GAIK BENG
IPC: A61P25/16
Filed: 2005-04-01
Abstract: Neurologically-active heterocyclic compounds of formula (I) comprising two fused 6-membered rings with nitrogen atoms at positions 1 and 3, a carboxy group at position 4, and a hydroxy group at position 8, with one ring being aromatic are disclosed. Processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological conditions, and more specifically neurodegenerative conditions such as Alzheimer's disease are also disclosed.
Patent NZ-553209-A (NZ)
Title: Airflow control mechanism for a conduit of a vacuum cleaner involving a series of apertures and a rotatable collar
Inventor: PEARS BARRY
Filed: 2007-02-14
Abstract: An airflow control mechanism comprising a conduit for air having an inlet 110 at the first end and an outlet 112 located at the second end. Several identical apertures 114 arranged in parallel along one side of the conduit provide a secondary air inlet. A rotating collar 120 containing a positional locking lever 22 is located in alignment with the apertures. This allows the collar to cover a selected number of apertures through the use of three preset collar positions and is activated by depressing the locking lever and selecting the desired aperture coverage.