baber/WOPTO huggingface dataset:
Patent PT-2264019-E (PT)
Title: Intermediates for the preparation of taxane derivatives
Inventor: FONTANA GABRIELE
IPC: C07D305/14
Filed: 2003-09-05
Abstract: A process for the preparation of compounds of formula XIV starting from compounds of formula XIII   
wherein 
R 2  is an acyl group or an alcohol-protecting group; 
R 3  is hydrogen, acyl, alkyl or, taken together with R 4 , forms a C=O, C=S, SO, SO 2  group; 
R 4  is hydrogen or, taken together with R 3 , forms a C=O, C=S, SO, SO 2  group; 
R 5  is hydrogen or an alcohol-protecting group; 
R 6  is aryl, substituted aryl, heteroaryl; 
comprising: 
a) selective reduction of the azido group to amino group; 
b) optional treatment with alkylating or acylating agents; 
c) cleavage of the C7 protective group; 
d) opening of the oxazolidine.
Patent PT-2387627-E (PT)
Title: Adaptive immunity profiling and methods for generation of monoclonal antibodies
Inventor: STEVEN R WILEY
IPC: C40B50/06
Filed: 2010-01-15
Abstract: Methods are provided for producing monoclonal antibody candidates using adaptive immunity profiling. In some aspects, the method provides for the use of massively parallel signature sequencing.
Patent PT-623352-E (PT)
Inventor: HOFFMANN DIETER
IPC: A61K47/48
Filed: 1994-04-25
Abstract: Provided herein are carbohydrate complement-modified bifunctional glycoproteins, and their use in tumor-selective therapy. The bifunctional glycoproteins comprise a first component that specifically binds to a tumor-specific antigen and a second component having enzymatic activity by means of which a non-toxic prodrug is cleaved into a cytotoxic drug. The carbohydrate complement comprises at least one exposed carbohydrate residue selected from the group consisting of mannose, galactose, N-acetylglucosamine, N-acetyllactose, glucose and fucose. The modified carbohydrate complement contributes to increased relative concentration of the glycoproteins at the site of the tumor, and enhanced clearance from the general circulation and non-tumor sites.
Patent PT-779943-E (PT)
Inventor: PRAINITO FRANCESCO ATTILIO
IPC: D03D27/08
Filed: 1995-08-29
Abstract: PCT No. PCT/AU95/00548 Sec. 371 Date Mar. 4, 1997 Sec. 102(e) Date Mar. 4, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/07782 PCT Pub. Date Mar. 14, 1996A method is described for manufacturing an item of terry cloth that incorporates a decorative panel. The item of terry cloth is woven with a panel that is loopless and double-sided. At least one face of the panel is formed of a synthetic fusible fiber. The fusible fiber is at least partially fused by applying heat and pressure to the face of the panel, thereby forming a smooth patterned surface on the face of the panel.
Patent PT-865557-E (PT)
Inventor: WURZ GERALD
IPC: E04H3/16
Filed: 1996-12-06
Abstract: PCT No. PCT/AT96/00242 Sec. 371 Date Jul. 17, 1998 Sec. 102(e) Date Jul. 17, 1998 PCT Filed Dec. 6, 1996 PCT Pub. No. WO97/21014 PCT Pub. Date Jun. 12, 1997In the described awning of variable size comprising a canvas (1, 2) which can be wound up on a shaft (3) provided with a drive, the canvas (1, 2) is fastened to the shaft (3), which has only one single drive, at a parting or folding line, and for winding up or unrolling the canvas parts (1, 2) provided by the parting or folding line, at least one tensioning rope (6, 6') is provided which engages at the canvas (1, 2) and which can be coiled up on the shaft (3) on at least one coiling pulley (5, 5') seated on the shaft.
Patent PT-792690-E (PT)
Inventor: VIS JEAN
IPC: B02C13/09
Filed: 1997-02-04
Abstract: The anvil is in the shape of a prism with flat upper and lower surfaces (22,24), a curved surface (16) forming part of a circle, two lateral surfaces (18,20) which come to a point, and two other lateral surfaces (26,28) adjacent to the curved surface. The two lateral surfaces adjacent to the curved surface are inclined at an angle between 3 degrees and 15 degrees to the median plane of the anvil and converge towards the upper or lower flat surface. One end of the anvil has projecting studs (26) to engage with holes in a ring, and the anvils are fitted into the ring with their inclined surfaces facing alternately in opposite directions.
Patent PT-907210-E (PT)
Inventor: SACHAU JURGEN
IPC: H01L31/02
Filed: 1998-09-28
Abstract: The photocell (2) is embedded within a module (1) that fits into a housing (8). The photocell has connections (3) to an energy conversion circuit (4a). The circuit has a connected coil that allows the electrical signal to be inductively transmitted to an adjacent coil in the housing that has an output circuit.
Patent PT-1019583-E (PT)
Inventor: JERNSTROM ROLF
IPC: E01F9/011
Filed: 1998-09-08
Abstract: The invention relates to a post (1), which is especially a hollow, tube-like piece and which is particularly intended for use as posts for traffic lights, street lights, signposts or similar, and which is formed of two layers. The inner layer (3) is of fibre-reinforced thermoset plastic and the outer layer (4) is of polyolefin plastic.
Patent PT-1015432-E (PT)
Inventor: DEMIAN IULIA
IPC: C07D217/20
Filed: 1998-09-02
Abstract: This invention describes a process for the isolation of (-)1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline from a racemic mixture, which involves treating partially resolved mixtures with a formic acid to form a nearly-racemic salt for further resolution.
Patent PT-1140637-E (PT)
Inventor: CARGILE DAVID W
IPC: B29C48/09
Filed: 1999-12-15
Abstract: A blow-molded plastic container (10) providing enhanced top loading capability. The container (10) has an inner peripheral surface (24) on which a plurality of integral, solid, inwardly and longitudinally extending ribs (26) are formed. Preferably, the ribs (26) extend throughout the entire container inner surface (24) from the top edge of the finish (20) to a mold parting line (28) on the base (14). A method and apparatus for making the container (10) is also disclosed.
Patent SG-10891-G (SG)
Title: Spring oil and spring assembly
IPC: A47C23/043
Filed: 1991-02-21
Abstract: A spring coil (11) has an open-ended terminal convolution (11b, 11c) which is connected to the body (11a) of the coil through a gradient arm (20) which can be varied in length in manufacture to alter the spring compression and firmness. Offset portions (12, 13, 14) are formed on each terminal convolution with a major straight part (13a) which is outwardly spaced from minor straight parts (13c) for a three point engagement for the offset portion to a border wire (18). The offset portions (12, 14) have inside (25a) and outside (25b) shoulders adjacent their ends, with the pitch of joing cross-helicals (17) chosen so that a cross-helical simultaneously engages the outside shoulders of a pair of overlapped offset portions (12, 14). The spring rows are further arranged across the width of the mattress, with the columns extending along the length. Cross-helicals (28) can then be used across portions of the width for extra firmness for the entire mattress, or for selected areas, such as the middle third.
Patent SG-54887-G (SG)
Title: Handle for tool with an e.g.retractable blade
IPC: B26B1/08
Filed: 1987-06-24
Abstract: 1. A tool handle (10) for a knife blade (15) which is held in it along a longitudinal axis (13) and is especially guided displaceably, and of which the front region of its handle back (30) adjacent to the knife point has a supporting surface (17) for an index finger (27) or for a thumb (26), and the two side cheeks of which each have on both sides of the supporting surface (17) a gripping recess (18, 19) for the thumb (26) or for a further finger of a working hand (29), each gripping recess (18, 19), starting from a lower central region (22), forming a wall (21) which rises rearwards in the pulling direction (23) of the knife blade (15), characterised in that the supporting surface (17) rises rearwards at an acute angle (alpha) to the longitudinal direction (13), in that each gripping recess (18, 19) has a drop-shaped contour (20) which extends in the longitudinal direction (13) of the tool handle (10) and which points forwards with its tapered region and rearwards with its rounded portion located opposite the tapered region, in that each gripping recess (18, 19) has a form matching the inner surface (25) of the thumb (26) or of the index finger (27), and in that the wall (21) of the gripping recess rises additionally, in the pushing direction (24) of the knife blade (15), in its region (21a) facing away from the supporting surface (17).
Patent SG-80692-G (SG)
Title: Oral compositions
IPC: A61K33/30
Filed: 1992-08-11
Abstract: Oral compositions which exhibit antimicrobial activity containing hexedine and a pharmaceutically acceptable zinc compound.
Patent SG-108991-G (SG)
Title: Lymphokine production and purification
IPC: C07K14/52
Filed: 1991-12-24
Abstract: A method for preparing and isolating a transformation vector containing CSF/cDNA is described. The method comprises:  preparing RNA from a cell that produces CSF;  preparing polyadenylated messenger RNA from said RNA;  preparing single stranded cDNA from said messenger RNA;  converting the single stranded cDNA to double stranded cDNA; inserting the double stranded cDNA into transformation vectors and transforming bacteria with said vector to form colonies; picking pools of 200 to 500 colonies each and isolating plasmid DNA from each pool; transfecting the plasmid DNA into suitable host cells for expressing CSF protein; culturing the transfected cells and assaying the supernatant for CSF activity; and selecting CSF positive pools and screening the colonies used to make the pool to identify a colony having CSF activity. Also described are a cDNA coding for a protein having CSF activity (i.e. CSF/cDNA), a microorganism or cell line transformed with a recombinant vector containing such CSF/cDNA, and a method for producing CSF protein by expressing said CSF/cDNA by culturing a microorganism or cell line. The invention also provides a method of purifying the CSF proteins and the purified proteins so produced.
Patent IE-800069-L (IE)
Title: Control for electric heater
IPC: H01H37/52
Filed: 1980-01-14
Abstract: A thermally-responsive electrical control for an electric heater of a water boiling container includes a switch-on-dry protector switch unit electrically connected with the cold leads of the heater and having a thermally sensitive switch means effective, in use, to interrupt the electrical supply to the heater should the element overheat through being switched-on when the container is dry. A removable steam-sensitive unit is mounted on the protector switch unit and includes an overcenter spring mechanism and a thermally-responsive actuator for the mechanism. The actuator of the said steam sensitive unit is arranged to impinged by vapor or steam issuing from the outlet of a passage leading to the interior of the container, and the electrical parts of the control are shielded from such vapor or steam. A mechanical link is provided between the overcenter spring mechanism and the switch means of the protector switch unit so that tripping of the overcenter spring mechanism by the actuator serves to operate the switch means of the protector switch unit. The steam-sensitive unit is optional and may be deleted to allow the switch-on-dry unit alone to control the heater.
[US4358666A]
Patent IE-850182-L (IE)
Title: Checking credit cards
IPC: G07F7/02
Filed: 1985-01-25
Abstract: 1. A device for the checking and cancellation of a value card (12) insertable in a card reader (1) for terminal equipment, especially card-operated telephones, and containing value units, having the following features : the card reader (1) has a slot (13), through which the value card (12) can be pushed into a card receptacle (3) corresponding to the size of the value card (12) ; the card receptacle (3) is designed so that the value card (12) is guided by it and, at its edge extending perpendicularly relative to the direction of insertion, is touched by a push-out hook (6) ; the card receptacle (3), together with the value card (12) so retained, can, as a result of a pivoting movement, be brought up to a contact element (19) serving for checking and cancellation ; there are means which, as a result of interlocking, allow the pivoting movement only when the value card (12) is inserted far enough into the card receptacle (3) ; after the pivoting movement has been executed, the card receptacle (3) can be stopped, by means of a blocking device (20, 21, 22) actuated by a magnet system, in a position differing from the insertion position and serving for checking and cancellation, up to the completion of cancellation, and can subsequently be returned to the initial position via spring elements, the value card (12) being ejected from the card reader (1) by the push-out hook (6) after cancellation has taken place, characterised in that the push-out hook (6) forms one arm of a transport rocker (2), the other arm of which is formed by two claws (5) engaging round the value card (12) at its edge located opposite the push-out hook (6), and in that the pivoting movement takes place as a result of the interlocking of the transport rocker (2) with a drive device, the value card (12) first being drawn into the card reader (1) completely and the slot (13) being closed by means of a blocking slide (4), and then the pivoting movement taking place.
Patent IE-880322-L (IE)
Title: Antiarrythmic agents
IPC: C07D307/81
Filed: 1988-02-05
Abstract: Title: "Antiarrhythmic Agents" Compounds of the formula: <IMG> ----- (A) and their salts, where R is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; R1 is C1-C4 alkyl; and "Het" is a group of the formula: <IMG> where R2 is H, CH3 or C2H5; R3 is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; and X is 0, S or NR4 where R4 is H or CH3; with the proviso that when one of R and R3 is -NO2, then the other is not -NH2. The compounds of the formula (A) in which both R and R3 are -NHSO2(C1-C4 alkyl) are antiarrhythmic agents. The reamining compounds of the formula (A) are synthetic intermediates. PLC 441
[CA1298840C]
Patent IE-42308-L (IE)
Title: 16,16-disubstituted androstenes
IPC: A61P17/00
Filed: 1976-03-01
Abstract: Pharmaceutically utilisable 3-ketosteroids which are disubstituted in position 16 and have the formula I <IMAGE> in which R3 are alkyl radicals with 1 to 5 carbon atoms, alkenyl or cycloalkyl radicals with 3 to 6 carbon atoms or phenylalkyl radicals with 1 to 3 carbon atoms in the alkyl radical, it being possible for the phenyl radicals to be substituted, R4 is the hydroxyl group or the radical -OR6 where R6 is an acyl radical with 2 to 7 carbon atoms, an alkyl radical with 1 to 4 carbon atoms, or the benzyl group which can be substituted, and R5 is a hydrogen atom or an alkyl radical with 1 to 5 carbon atoms, it also being possible for R4 and R5, together with the carbon atom to which they are bonded, to form the carbonyl group, are obtained by removing the protective group in the compound of the formula I in which the double bond is in the 5,6 position and the 3-carbonyl group is protected by ketal, hemithioketal or thioketal. The double bond rearranges during the elimination and provides the required 4,5 bond in the final product. The prepared compounds are particularly valuable for the treatment of androgen-dependent skin disorders such as acne and seborrhoea and of other androgen-dependent disorders associated with skin and hair glands.
[GB1538227A]
Patent IE-900494-L (IE)
Title: Cross-linked antibodies and processes for their preparation
IPC: A61K47/48
Filed: 1990-02-12
Abstract: Cross-linked antibody conjugates are described which have at least one interchain bridge containing a reporter or effector molecule. The bridge may be the residue of a homo- or hereofunctional cross-linking reagent, and is located away from the antigen binding domains of the antibody. The antibody conjugates have an enhanced binding capacity and in vivo have good blood clearance and, in the presence of a tumour high tumour: blood and tumour: bone ratios. The conjugates are of use in the diagnosis and therapy of e.g. tumours and may be prepared by reaction of a cross-linking reagent with an antibody.
Patent IE-840496-L (IE)
Title: Resolution of trans-3-£4-methoxyphenoxy)-methyl| -1-¹methyl-4-phenylpiperidine
IPC: C07D211/22
Filed: 1984-03-01
Abstract: A mixture of enantiomers of trans-3-[(4-methoxyphenoxy)-methyl]-1-methyl-4-phenylpiperidine is separated into the optically active pure forms by reacting it with an enantiomer of mandelic acid or a derivative thereof to form two diastereomeric compounds and by precipitating one of the diastereomeric compounds formed. The precipitated compound is subsequently separated and is optionally converted into the free base or a pharmaceutically acceptable salt thereof. The yield obtained is substantially higher than the yield obtained by a prior art process employing a tartaric acid derivative as resolving agent.
Patent IE-820532-L (IE)
Title: Firing solid fuels
IPC: F23H15/00
Filed: 1982-03-09
Abstract: This invention relates to a boiler installation for the combustion of solid fuels, for example forest waste material in the form of e.g. bark and or chips, peat pellets, coal etc., which installation comprises a furnace located in connection to a heat medium portion and a grate means located in the furnace, which grate means feeds fuel from a fuel charge opening through the furnace while the fuel is being combusted, from which furnace the flue gases flow to the heat medium portion and continue to a chimney, and at least one intake for controlled supply of combustion air in the form of at least primary and secondary combustion air. In order to improve the efficiency degree of such boiler installations and to render possible efficient and complete combustion of forest waste material and other biologic fuels, which may have a high moisture content, the rear portion of the grate means (4) of the boiler installation, seen in the direction of movement, is located outside of the furnace space (1) proper but connected thereto for forming a zone in connection to the charge opening (5 for a certain drying of the fuel before it is fed into the furnace (1) by the grate, and comprises transverse dogs (9) running on a grate plane for advancing the fuel through the furnace (1), which grate plane is located above means (25,26) for the supply of the primary combustion air from below to the fuel, and below the air intakes (29) for the secondary combustion air.
Patent IE-780547-L (IE)
Title: Tape cassette container
IPC: G11B23/00
Filed: 1978-03-20
Abstract: The container with the exchangeable magnetic tape cassette located therein comprises a rectangular housing (1) and a slide-in unit (2), which can move along a narrow side of the housing and receives the tape cassette, as well as a compression spring (3), which acts between the rear wall (23) of the slide-in unit and the rear side (8) of the housing. After the release of a holding device (31, 35), the compression spring pushes the slide-in unit together with the tape cassette by an amount out of the housing into an open position, in which the tape cassette can be removed unhindered from the container. The push-in unit has the form of a four-sided frame which leaves the bottom (10) of the housing free and which at least partially embraces the tape cassette lying on the bottom. In the open position, at least the frame part protruding out of the container takes up an oblique position with respect to the bottom of the housing, releasing the cassette on all sides, so that one-handed operation for loading and removal is possible. It is also advantageous that the container allows music tape cassettes to be loaded in four different orientations and coincides in its dimensions with conventional cassette boxes. <IMAGE>
[GB1573880A]
Patent IE-34132-L (IE)
Title: Biological slurry treatment
IPC: C02F11/13
Filed: 1970-05-04
Abstract: A method of treating an aqueous biological slurry comprising the steps of feeding the slurry through an evaporator plant where it is subjected to heat treatment and where a part of its water content is removed by evaporation, filtering the slurry which has passed through the evaporation plant and recycling the aqueous filtrate for further treatment with the slurry in the evaporator plant and an installation for performing same.
[US3650403A]
Patent IE-44197-L (IE)
Title: Liquid and solid grain feeder for animals
IPC: A01K5/015
Filed: 1976-03-19
Abstract: The apparatus of this invention more positively controls liquid feed and solid (grain) feed consumption by animals in a simple economical and efficient manner, while minimizing contamination and wastage problems. Basically, the invention comprises in combination (1) a lick wheel rotatably mounted in an enclosed liquid feed container, with a portion of the circumference of the liquid wheel being exposed to the animal to be fed, (2) a means for adjusting the amount of lick wheel surface exposed to the animal to be fed, to thereby control the amount of liquid feed consumed by the animal per tongue lick, (3) means for discharging solid feed to the animal in an amount proportional to the amount of rotation of the lick wheel to obtain thereby a fixed ratio of solid to liquid feed, to be fed to the animal, and (4) means for varying the solid feed discharge independently of the amount of rotation of the lick wheel so as to increase or decrease the fixed ratio of solid to liquid feed fed to the animal.
[US3952705A]
Patent IE-34332-L (IE)
Title: Constructing a lined tunnel.
IPC: F16L9/22
Filed: 1970-06-08
Abstract: A method of constructing a lined tunnel comprises the steps of excavating a short length of tunnel of internal diameter greater than the external diameter of the lining, erecting within the said length of tunnel a ring of three 120 DEG lining segments, repeating the steps of excavating a short length of tunnel and erecting a lining ring within the short length, and pressing each successive ring into endwise engagement with the previously erected ring.
[US3640076A]
Patent IE-800836-L (IE)
Title: Reducing phase noise in transmission system
IPC: H04L25/03
Filed: 1980-04-25
Abstract: Data in the form of multi-value symbols is transmitted at a symbol rate 1/ DELTA T. At the receiver a decision circuit supplies estimates of the transmitted symbols on the basis of the received symbols. The present invention concerns compensating phase noise after equalization, if any, of the received symbols and before application of the received symbols to the decision circuit (38, 39). The received symbols are in complex form with in-phase and quadrature components yk' and yk'' respectively. Phase noise is compensated by complex multiplication in a multiplier (36) of the received symbols by a complex coefficient mk mk+1=[mk- lambda (vk-ak)yk*]exp[-iFk( epsilon j)] where: lambda is a real coefficient; yk* is the complex conjugate of the symbol received at instant k DELTA T+to (where to is the instant taken as the origin of time measurements); vk is the symbol applied to the decision circuit at said instant; ak is the estimated value of the received symbol; epsilon j is an error signal derived from the phase difference between the symbol applied to the decision circuit and the symbol estimated by the decision circuit at instant j DELTA T+to; and Fk( epsilon j) is a linear function of at least the error signals epsilon j. The invention is particularly applicable to quadrature modulation systems, but if only one channel is transmitted the quadrature channel can be simulated using the Hilbert transform of the one channel.
[US4306307A]