Patent SG-194974-A1 (SG)
Title: Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea
Inventor: RUSSO ANDREW F
Filed: 2012-05-21
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT)(19) World Intellectual Property OrganizationInternational Bureau(43) International Publication Date 29 November 2012 (29.11.2012) WIPO I PCT (10) International Publication NumberWO 2012/162253 A2 (51) International Patent Classification:A61K 39/395 (2006.01) A61K 31/7088 (2006.01)A61K 48/00 (2006.01) A61P 1/12 (2006.01)A61K 38/16 (2006.01)International Application Number: PCT/U52012/038869International Filing Date: 21 May 2012 (21.05.2012)Filing Language: EnglishPublication Language: English(30) Priority Data:61/488,660 20 May 2011 (20.05.2011) US61/496,873 14 June 2011 (14.06.2011) USApplicants (fo- all designated States except US): ALDER BIO HOLDINGS LLC [US/US]; 101 Convention Center Dr., Ste. 850, Las Vegas, Nevada 89109 (US). THE UNI VERSITY OF IOWA RESEARCH FOUNDATION [US/US]; 2660 University Capitol Center, Iowa City, Iowa 52242-5500 (US).Inventors; and(75) Inventors/Applicants (fo- US only): RUSSO, Andrew F. [US/US]; 1762 Winston Dr., Iowa City, Iowa 52245 (US). KAISER, Eric A. [US/US]; 4924 E. Court St., Iowa City, Iowa 52245 (US). RECOBER, Ana [US/US]; 15 Cherry Ln. NE, Iowa City, Iowa 52240 (US). KUBURAS, Adisa [US/US]; 1480 Harvest St., North Liberty, Iowa 52317 (US). RADDANT, Ann C. [US/US]; 460 Samoa Dr., Iowa City, Iowa 52246 (US). KOVACEVICH, Brian Robert [US/US]; 13916 233rd St. SE, Snohomish, Washington 98296 (US). LATHAM, John A. [US/US]; 2409 10th Ave. NW, Seattle, Washington 98119 (US). SMITH, Jef frey T.L. [GB/US]; 10270 NE 12th St., Apt. F307, Bel levue, Washington 98004 (US). GARCIA-MARTINEZ, Leon F. [US/US]; 4926 214th St. SE, Woodinville, Wash ington 98072 (US). (74) Agent: TESKIN, Robin L.; Bunton & Williams LLP, 2200 Pennsylvania Ave. NW, Washington, District of Columbia 20037 (US).(81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, Fl, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.(84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, Fl, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).Declarations under Rule 4.17:as to the identity of the inventor (Rule 4.170)as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii))as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii))Published:; title not checked by the International Searching Authoritywith sequence listing part of description (Rule 5.2(a))