baber/WOPTO huggingface dataset:
Patent DE-68929151-D1 (DE)
Inventor: WELLS JAMES A
IPC: C12Q1/68
Filed: 1989-10-30
Granted: 2000-03-09
Abstract: The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting selected amino acid segments of the polypeptide with an analogous polypeptide segment from an analog to the polypeptide. The analog has a different activity with the target substance as compared to the parent polypeptide. The activities of the segment-substituted polypeptides are compared to the same activity for the parent polypeptide for the target. A comparison of such activities provides an indication of the location of the active domain in the parent polypeptide. The invention also provides methods for identifying the active amino acid residues within the active domain of the parent polypeptide. The method comprises substituting a scanning amino acid for one of the amino acid residues within the active domain of the parent polypeptide and assaying the residue-substituted polypeptide so formed with a target substance. The invention further provides polypeptide variants comprising segment-substituted and residue-substituted growth hormones, prolactins and placental lactogens.
Patent DE-69006106-D1 (DE)
Inventor: ERJALA MATTI
IPC: C05F11/00
Filed: 1990-05-30
Granted: 1994-03-03
Abstract: The invention concerns a method for growth regulation the purpose of which is to increase the growth of the root of a plant. In this method fresh bark is dosed to the culture medium. The method is suitable to be used in cultivation of f.ex. root plants.
Patent DE-69006742-D1 (DE)
Inventor: WALTON BRIAN THE WARREN
IPC: G01L5/24
Filed: 1990-11-13
Granted: 1994-03-24
Abstract: PCT No. PCT/GB90/01746 Sec. 371 Date Apr. 16, 1992 Sec. 102(e) Date Apr. 16, 1992 PCT Filed Nov. 13, 1990 PCT Pub. No. WO91/08398 PCT Pub. Date Jun. 13, 1991.A load indicating fastener such as a bolt (10) or stud, has a shank (12) which is subject to tensile loading in use. The shank (12) has an axially extending bore (22) which receives a first gauge pin (30) anchored at its inner end (32) to the shank (12) and protruding outwards beyond an end face (16) of the fastener. An indicating member (40) is rotatable on the protruding portion of the gauge pin (30) between the end face (16) of the fastener and the head (34) of the pin (30), so that the indicating member (40) is free to rotate when the shank (12) of the fastener is unstressed but when the shank (12) is subject to a predetermined tensile loading is held against rotation by contact with the end face (16) of the fastener. A second gauge pin (42) is received within an axially extending bore (36) in the first gauge pin (30) and is anchored at is inner end and protrudes outwards beyond the outer end of the first gauge pin (30). A second indicating member (50) is rotatable on the protruding part of the second gauge pin (42), between the head (46) of the pin (42) and the first indicating member (40). The second indicating member (50) is free to rotate when the shank (12) of the fastener is unstressed or subject to the first predetermined loading, but when the shank (12) is subject to a second predetermined tensile loading greater than the first predetermined loading, the second indicating member (50) is held against rotation by contact with the first indicating member (40). The first indicating member (40) provides an indication when the fastener has been tightened to a desired loading. The second indicating member (50) provides an indication when the fastener has been overloaded.
Patent DE-69009530-D1 (DE)
Inventor: LHOSPICE BERNARD
IPC: G02C5/20
Filed: 1990-02-05
Granted: 1994-07-14
Abstract: Spectacle frame side having an adaptable profile. 
<??>According to the invention, the frame side comprises a side body (12) and a side end-piece (13) mounted so as to rotate on itself at one end of the side body, the said side end-piece comprising two opposed edges (17, 18) having significantly different curvatures. 
<??>Application to a spectacle frame which is better adapted to the practice of a sporting activity. 
<IMAGE>
Patent DE-69016183-D1 (DE)
Inventor: GUACIARO MICHAEL ANTHONY
IPC: C07D233/70
Filed: 1990-11-14
Granted: 1995-03-02
Abstract: 2-(1-Substituted-2-imidazolin-2-yl)benzoic and nicotinic acids, and derivatives thereof, which are effective in the control of undesirable plant species are described. Also described are a method for the herbicidal use of the compounds and a method for their preparation.
Patent DE-69021923-D1 (DE)
Inventor: KALINOWSKI PAUL W
IPC: C04B35/10
Filed: 1990-04-27
Granted: 1995-10-05
Abstract: Resinoid and vitrified bonded abrasive products containing filament shaped sintered alumina based abrasive made up predominantly of fine alpha alumina crystals.
Patent DE-69031928-D1 (DE)
Inventor: AX ROY L
IPC: A61K38/00
Filed: 1990-07-30
Granted: 1998-02-19
Abstract: A method is disclosed relating to the isolation and purification of certain heparin-binding protein compositions in the seminal plasma of male mammals. The isolated proteins are useful in fertility studies and in enhancing the acrosomal reaction, capacitation and subsequent fertility of sperm cells.
Patent DE-69033543-D1 (DE)
Inventor: LOKHOFF GERARDUS CORNELIS PETR
IPC: G10L19/02
Filed: 1990-05-29
Granted: 2000-06-15
Abstract: The audio transmission system samples and digitizes the audio input and separates it into subbands defined for psychoacoustic factors. The signals are pre-amplified (46) and then quantized (48) and combined for transmission. The pre-amplification if performed by using a multiplier having a relationship with 2 k>.g(p). The g(p) function has binary patterns for different values of p=0,1 and 2. The pre-amplifier also generates an n-bit binary scale value identifier of 3k+p.
Patent DE-69105207-D1 (DE)
Inventor: BOWERS CYRIL
IPC: C07K14/60
Filed: 1991-07-23
Granted: 1994-12-22
Abstract: Novel polypeptides which promote the release of growth hormone when administered to animals are described. These polypeptides have the formula: A1-D< beta >Nal-A3-Trp-A5-A6-Z or AW1Q-DPhe-A3-Trp-A5-A6-Z.
Patent DE-69105303-D1 (DE)
Inventor: CAPPELLARI ROBERTO
IPC: B30B9/30
Filed: 1991-03-04
Granted: 1995-01-12
Abstract: The process for compacting waste materials comprises a first step of compression of the waste materials, with squeezing and separation of a first liquid phase, a second step of feeding the compressed materials to self-compaction chambers, in which a second compression of the materials is performed with separation of a second liquid phase, the heating of the compacted materials, and the cooling of the compacted materials. The apparatus for compacting waste materials comprises a pair of compression rollers (4) arranged above a double-scroll feeder (5) which unloads the material inside containers (9) which can slide on a transfer line (10), at the beginning of which there is a compacting press (18). The transfer line (10) comprises, in succession, a heating tunnel (24), a cooling tunnel (26) and finally a station (29) for unloading the compacted elements. <IMAGE>
Patent DE-69106619-D1 (DE)
Inventor: ISMAIL MUHAMMAD ALI
IPC: B30B9/30
Filed: 1991-02-19
Granted: 1995-02-23
Abstract: The present invention relates to a domestic waste processor (1). The processor (1) comprises a housing (2) having a plurality of inlet apertures (6) connected by delivery chutes (8) to a compactor (10) for compacting waste material (24) passing down the chute (8). The processor (1) is provided with removable containers (4) for collection of processed waste material (34). In use of the processor (1) a plurality of different types of waste (24) may be introduced into respective inlet apertures (6), compacted, and then collected in respective containers (4) which may be periodically emptied or disposed of.
Patent DE-69129927-D1 (DE)
Inventor: CAMBLE ROGER
IPC: A61K38/00
Filed: 1991-04-29
Granted: 1998-09-10
Abstract: Derivatives of naturally occurring G-CSF having at least one of the biological properties of naturally occurring G-CSF, and a solution stability of at least 35% at 5 mg/ml are disclosed in which the derivative has at least Cys<1><7> of the native sequence replaced by a Ser<1><7> residue and Asp<2><7> of the native sequence replaced by a Ser<2><7> residue. Nucleotide sequences coding for part or all of the amino acid sequence of the derivatives of the invention may be incorporated into autonomously replicating plasmid or viral vectors employed to transform or transfect suitable procaryotic or eucaryotic host cells such as bacteria, yeast or vertebrate cells in culture.
Patent DE-69133274-D1 (DE)
Inventor: ALBIZZATI ENRICO
IPC: C08F4/658
Filed: 1991-03-28
Granted: 2003-07-10
Abstract: Catalyst components for the polymerization of olefins comprising a titanium halide or alkoxyhalide and an electron-donor compound selected from ethers having two or more ether groups and containing at least one heteroatom selected from the group consisting of N, S, P, Si, non-ether O and halogen atoms or at least one double bond, or both at least one heteroatom and at least one double bond, supported on a magnesium halide in active form. Catalysts obtained from said catalyst components and an Al-alkyl compound.
Patent DE-69204119-D1 (DE)
Inventor: LEFEBVRE LOUIS
IPC: E04G11/02
Filed: 1992-06-10
Granted: 1995-09-21
Abstract: The invention relates to a method for erecting and dismantling the shuttering of walls (1) made from a cast material erected above a reference surface (2) especially with the aid of elements of sheeting (3), each comprising a shuttering face (4) and equipped with casters (31, 32) at their base. This method is characterised in that:     - for the shuttering:   . from the dismantled position of the shuttering, by tilting at least the base (29) of the shuttering face (4) of the sheeting (3) towards the wall (1) to be shuttered, thereby for this purpose revolving about an axis substantially defined by the bearing points (10) of the casters (31) on the reference surface, the lower edge (35) of the shuttering face (4) is brought to bear on the reference surface (2) then, . by continuing the tilting of at least the base (29) of the shuttering face of the sheeting (3) towards the wall (1) to be shuttered, but by revolving, for this purpose, about an axis substantially defined by the lower edge (35) of the shuttering face of the sheeting (3), the casters (31) are lifted off the reference surface and     - for dismantling the shuttering, the operations are reversed.   Application to the building industry and to shuttering equipment. <IMAGE>
Patent DE-69209085-D1 (DE)
Inventor: BROWNING JOHN
IPC: A61F13/32
Filed: 1992-10-29
Granted: 1996-04-18
Abstract: PCT No. PCT/GB92/01980 Sec. 371 Date Jun. 29, 1994 Sec. 102(e) Date Jun. 29, 1994 PCT Filed Oct. 29, 1992 PCT Pub. No. WO93/08779 PCT Pub. Date May 13, 1993The present invention relate to a sanitary tampon comprising a compact applicator and a tampon (3) of compressed absorbent material stored within the applicator, the applicator having an inner tube (1) and an outer tube (2) slidably disposed over the inner tube (1). The outer tube (2) has a distal discharge end (4) for insertion into the body of the user. The tampon (3) is solid and substantially cylindrical in shape and is constructed such that at least a part of the body (11) of the tampon (3) adjacent the proximal end (13) sits at an angle to the longitudinal axis of the applicator so that when the inner tube (1) is withdrawn past the proximal end (13) of the tampon (3) to prime the applicator for use, the proximal end (13) of the tampon will urge itself against the inner surface of the outer tube (2) and when the inner tube (1) is pushed back into the outer tube (2) to expel the tampon, the tampon is hindered from re-entering the distal end (6) of the inner tube (1).
Patent DE-69212204-D1 (DE)
Inventor: BASIN GERARD
IPC: B05D7/24
Filed: 1992-04-10
Granted: 1996-08-22
Abstract: The present invention relates to a method and a device for making a bituminous mixture. 
<??>The method for making bituminous mixtures reinforced with fibrous materials is characterised in that the fibrous materials are introduced directly and in a continuous manner into the liquid bitumen. 
<IMAGE>
Patent DE-69213184-D1 (DE)
Title: Phospholipase a2 inhibitor
Inventor: OHTANI MITSUAKI
IPC: C07C229/36
Filed: 1992-06-24
Granted: 1996-10-02
Abstract: A novel thielocin derivative having a phospholipase A2 inhibitory activity, represented by general formula (I), or a salt thereof, wherein R<1> to R<8> represent each independently hydrogen, lower alkyl, lower alkoxy, hydroxy or halogen; E1 and E2 represent each independently hydrogen or an ester residue; m and n represent each independently an integer of 0 to 4; and -Y- represents a divalent group selected among those represented by the following formulae -CH2CH2-, -CH = CH-, (II), (III), (IV), (V), (VI), (VII). <CHEM>
Patent DE-69216848-D1 (DE)
Inventor: GEERTS JAN
IPC: E01C13/00
Filed: 1992-10-09
Granted: 1997-02-27
Abstract: PCT No. PCT/NL92/00182 Sec. 371 Date Jun. 30, 1994 Sec. 102(e) Date Jun. 30, 1994 PCT Filed Oct. 9, 1992 PCT Pub. No. WO93/08332 PCT Pub. Date Apr. 29, 1993.The invention relates to a device (51) for inserting elongated artificial grass fibres (30) into the ground. The device (51) is provided with a frame (40), which is movable across the ground and which has at least one planting pin (25) being movable up and down in the frame (40), as well as with means for placing an artificial grass fibre (30) to be inserted into the ground under said planting pin (25), in such a manner that the fibre in question can at least partially be pressed into the ground by the planting pin (25) subsequently moving downwards. Preferably the device is provided with a plurality of planting pins (25), which are arranged in a row extending transversely to the intended direction of movement of the device, and which can jointly be moved up and down with respect to the frame by setting means.
Patent DE-69217728-D1 (DE)
Inventor: MANDON MICHEL
IPC: E05C17/30
Filed: 1992-06-05
Granted: 1997-04-10
Abstract: The present invention relates to an actuating device for casements. The device is characterised in that it comprises two telescopic arms (1, 5) forming compasses after they have been extended from their position retracted behind the shutters (2, 6), in such a way that, when a push is exerted in the vicinity of the vertex of the compasses, the two extended arms (1, 5) push the two shutters (2, 6) simultaneously in order to cause them to pivot into their open position. The invention is used particularly for opening and closing shutters of a window. <IMAGE>
Patent DE-69220323-D1 (DE)
Inventor: PIROTTA GIAMPIERO DR
IPC: C08L53/02
Filed: 1992-10-30
Granted: 1997-07-17
Abstract: Disclosed is a thermoplastic coupled multilayer structure comprising:     (A) at least one layer of a blend of (i) a vinylaromatic polymer and (ii) a vinylaromatic monomer-conjugated diene block copolymer;   (B) at least one polyolefin layer, and, optionally,   (C) one or more layers of vinylaromatic polymer. t
Patent DE-69224711-D1 (DE)
Inventor: MORINI GIAMPIERO
IPC: C08F2/44
Filed: 1992-12-11
Granted: 1998-04-16
Abstract: Polyolefins stabilized against oxidation phenomena are obtained by using a process comprising the polymerization of monomers by way of a catalyst prepared by reacting an aluminum alkyl compound, and optionally an electron donor compound, with a solid component comprising a Ti compound and an electron-donor compound supported on magnesium chloride, the polymerization being carried out in the presence of one or more phenolic stabilizers and using, as electron-donor compound in the solid catalyst component, a compound selected from particular classes of ethers.
Patent DE-69231673-D1 (DE)
Inventor: CRYZ J
IPC: A61K47/48
Filed: 1992-08-11
Granted: 2001-03-08
Abstract: The present invention relates to a method of producing an E. coli vaccine and to the vaccine produced thereby. The method involves purifying lipopolysaccharide from E. coli expressing complete O-polysaccharide sidechains;isolating the O-polysaccharide region of the lipopolysaccharide molecule by hydrolysis in dilute acetic acid and purifying it essentially free of lipid A; and covalently coupling lipid A-free O-polysaccharide via at least one hydroxyl or carboxyl group of the polysaccharide to a carrier protein. Polyvalent vaccines are prepared by combining two or more monovalent vaccines for different serotypes prepared according to the present invention. The present also relates to conjugates used in the vaccines. The conjugates of the present invention are the O-polysaccharide region of an E. coli lipoplysaccharide molecule covalently coupled to a carrier protein.
Patent DE-69306094-D1 (DE)
Inventor: UENO HIROAKI
IPC: A61K31/41
Filed: 1993-12-28
Granted: 1997-01-02
Abstract: Naphthalene derivatives represented by the formula (I): <CHEM>  wherein the symbol <CHEM>  represents <CHEM>  -X- represnts -O- or -S-,  =Y- represents =N- or =CR<5>-, R<1>, C<2>, R<3>, R<4> and R<5> represent hydrogen, halogen, alkyl and the like,  R<6> represents hydrogen, alkyl, aryl and the like,  n represents an integer of 0 to 3, --- represents a single bond or a double bond, which are useful for reducing blood sugar and blood lipid levels are provided.
Patent DE-69312743-D1 (DE)
Inventor: SEILER DIETER G
IPC: G07F7/10
Filed: 1993-12-24
Granted: 1997-09-04
Abstract: PCT No. PCT/CA93/00560 Sec. 371 Date Jun. 22, 1995 Sec. 102(e) Date Jun. 22, 1995 PCT Filed Dec. 24, 1993 PCT Pub. No. WO94/16415 PCT Pub. Date Jul. 21, 1994An anti-fraud system for the dispatch of credit cards to customers, rendering the new card useless to anyone other than the intended customer. Validation of the new card is accomplished at any retail outlet by means of a timed sequence at the transaction processing computer which ensures that any first-time sales authorization request under the new card is followed immediately within a prescribed time interval by a reading of the old credit card number and expiry date. The system also operates if the old card is tendered first at a sales outlet after the new card has been issued. This unique sequence of events will then automatically invalidate the old card, validate the new card, and indicate to the card issuing company that the customer has acknowledged receipt of their new card. Since both the old, expiring card, and the new card are required in order to validate the new card, an unauthorized party in illegal possession of the new card only, cannot use it.
Patent DE-69321592-D1 (DE)
Inventor: LIU YING
IPC: G01N33/49
Filed: 1993-07-22
Granted: 1998-11-19
Abstract: PCT No. PCT/GB93/01544 Sec. 371 Date Apr. 7, 1995 Sec. 102(e) Date Apr. 7, 1995 PCT Filed Jul. 22, 1993 PCT Pub. No. WO94/02846 PCT Pub. Date Feb. 3, 1994An apparatus and method for determining a property of a sample, derived from a response obtained from the sample after an electrical pulse has been applied to it. Blood cells are subjected to an electrical pulse, a response is obtained using data retrieval means and a Fourier Transform is applied to the response. As the pulse applied is of very short duration (ideally a Dirac pulse) the Fourier transform yields information across a very broad bandwidth, typically several MHz, and accordingly a wide range of frequency response data is obtained. Certain cellular defects can be deduced from the transformed data. A detector is provided to detect precisely the presence of a cell as it passes through a particular region of an oriface. This is then used to trigger the pulse at a precisely controlled instant. This reduces the effect of random dispersion and can be adapted to ignore noise peaks which inevitably occur. The invention may be operated continuously and provides information across a bandwidth which is wider than was previously possible.
Patent DE-69321779-D1 (DE)
Inventor: GASSELING GERARDUS FRANCISCUS
IPC: G11B17/04
Filed: 1993-07-08
Granted: 1998-12-03
Abstract: A device for the recording and reproduction of signals on a cassette for a medium comprising a sliding cover which in the device can be moved between a closed position and an open position. The device has a receiving space into which the cassette can be inserted, after which by means of a pivotal lever the sliding cover is opened upon further insertion of the cassette, in that the lever moves from the first position to the second position and thereby moves the sliding cover from a closed position to an open position. The lever is arranged on a movable lever support which can be moved between a staring position and an end position. The sliding cover is opened by snap action.
Patent DE-69324726-D1 (DE)
Inventor: BECKWITH STEVEN PAUL
IPC: C09K3/00
Filed: 1993-02-25
Granted: 1999-06-10
Abstract: A soda-lime-silica green glass favoring the yellow side, rather than the bluish side of the spectrum, is produced having high visible transmittance, low infrared energy transmittance, low ultraviolet radiation transmittance, and low total solar energy transmittance by manipulating the reduction of iron (as Fe203) to Fe0 and the percent of these two oxides to achieve these characteristics without the use of Ce02 or other UV absorbing additives and by using conventional glass melting and refining apparatus. <IMAGE>
Patent DE-69326261-D1 (DE)
Inventor: ROWLAND SIMON
IPC: G02B6/48
Filed: 1993-05-07
Granted: 1999-10-07
Abstract: PCT No. PCT/GB93/00947 Sec. 371 Date Oct. 25, 1994 Sec. 102(e) Date Oct. 25, 1994 PCT Filed May 7, 1993 PCT Pub. No. WO93/23779 PCT Pub. Date Nov. 25, 1993.A method of installing an optical cable in an overhead power transmission line by supporting an optical cable, which has an overall protective sheath of electrically insulating material, in long lengths between towers employed to support at least one electric power transmission line which is on load and, after the optical cable has been so installed and while the overhead electric power transmission line is on load, providing on or in the supported optical cable at least one longitudinally continuous path which extends throughout substantially the whole length of the supported optical cable and which is sufficiently electrically conductive to carry along the cable any currents that may be capacitively induced. The method enables a cable that will not be subject to dry-band arcing to be installed without danger to personnel during installation.
Patent DE-69404633-D1 (DE)
Inventor: LAWSON ANTHONY CHARLES
IPC: A47J43/046
Filed: 1994-02-18
Granted: 1997-09-04
Abstract: A mixer having a container (14), an opened topped hollow sleeve (20) adjacent the lower surface of the container, at least one opening (22) into the sleeve adjacent the lower edge thereof, a screw impeller (25) located in the sleeve and driving means for the impeller (11) whereby material to be mixed can enter the sleeve through the opening adjacent the lower end thereof, be mixed by the impeller and delivered through the open top of the sleeve. The invention also provides an impeller (60) which can be formed to act to cut material passing through the sleeve as well as to mix this material.
Patent DE-69410790-D1 (DE)
Inventor: SCHNUR RODNEY
IPC: A61P35/00
Filed: 1994-03-14
Granted: 1998-07-09
Abstract: This invention relates to compounds of the formuladefined below. Such compounds are useful as oncogene inhibitors and antitumor agents.
Patent DE-69413923-D1 (DE)
Inventor: WARANIS ROBERT PAUL
IPC: A61K31/435
Filed: 1994-09-29
Granted: 1998-11-19
Abstract: Disclosed herein is an aqueous, injectable rapamycin solution comprising 40 to 75 volume percent of a concentrate solution of rapamycin in propylene glycol, at concentrations of rapamycin ranging from 0.25 mg/ml to 8 mg/ml, in combination with a diluent solution comprising water, wherein the diluent comprises 60 to 25 volume percent of the combined solution and the concentration of rapamycin in the combined solution ranges from 0.1mg/ml to 4 mg/ml.