baber/WOPTO huggingface dataset:
Patent CA-2400862-A1 (CA)
Title: Thiazepinyl hydroxamic acid derivatives as matrix metalloproteinase inhibitors
Inventor: MUKAI NORIKO
IPC: C07D417/06
Filed: 2001-02-20
Abstract: A compound of formula (I) in which R1 is halo, lower alkoxy, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heterecyclic group or optionally substituted lower alkynyl, R2 is amidated carboxy, R3 is hydrogen or acyl, Ar is aryl or heterocyclic group, X is thia, sulfinyl or sulfonyl, Y and Z are each lower alkylene, m and n are each an integer of 0 to 2, and a salt thereof, useful as inhibitors of matrix metalloproteinases (MMP) or the production of tumor necrosis factor .alpha.  (TNF .alpha.).
Patent CA-2404100-A1 (CA)
Title: Therapeutic peptides having a motif that binds specifically to non-acetylated h3 and h4 histones for cancer therapy
Inventor: GALVEZ ALFREDO F
IPC: C12N15/29
Filed: 2001-03-23
Abstract: The present invention describes a composition of matter comprising a conserved structural motif that allows the targeting and binding of a chromatin binding protein to non-acetylated histone H3 and H4 and prevents their acetylation.  This invention is responsible for the anti-carcinogenic property of a chromatin binding peptide isolated from soybean seed. This structural motif is found in a highly conserved manner in other chromatin-binding proteins from different species. Modifications to this structural motif such as fusions to other proteins with functional motifs and amino acid substitutions have potential therapeutic applications and can be developed as an in vivo gene silencing technology for biological and medical research. In particular, active fragments of the lunasin peptide and active analogs of the lunasin peptide are useful in this invention. Pharmaceutical compositions useful in retarding or stopping or reducing various types of cancers are described.
Patent CA-2404704-A1 (CA)
Title: Traitement de la cellulomyalgie et du syndrome de fatigue chronique
Inventor: ROBERTSON DAVID W
IPC: A61K31/48
Filed: 2001-04-17
Abstract: La présente invention concerne le traitement de troubles neuromusculaires et plus précisément, l'emploi d'apomorphine, de bromocriptine, de pergolide, de ropinirole, d'octahydropyrazolo[3,4-g]quinolines, et de -5,5a,6,7,8,9-,9a,10-octahydropyrimido[4,5g]quinolines trans-(.plusmn.)-substituées, ainsi que des sels pharmaceutiquement acceptables de ces composés pour le traitement, ou la préparation de médicaments, pour le traitement des symptômes de la cellulomyalgie et du syndrome de fatigue chronique.
Patent CA-2407068-A1 (CA)
Title: Antigenic peptide fragments of vapa protein, and uses thereof
Inventor: HEUZENROEDER MICHAEL W
IPC: A61K39/00
Filed: 2001-04-27
Abstract: An isolated peptide fragment of the Vap A protein that binds antibodies specific for Rhodococcus equi and the VapA protein. In a preferred form the peptide contains an amino acid sequence of 5 or more amino acid residues that is identical to or homologous to the amino acid sequence of at least one region of the VapA protein that is responsible for immunological recognition.  Methods of diagnosing a vertebrate for the presence of R. equi using the peptide and methods of vaccinating a vertebrate against R. equi using the peptide are also claimed.
Patent CA-2407844-A1 (CA)
Inventor: REINHARD GERALD JOSEF
IPC: H04N1/191
Filed: 2001-04-30
Abstract: L'invention concerne un dispositif permettant l'inspection (10,11,12), le marquage (9) ou tout autre traitement ou observation d'une feuille d'impression (1) transportée à repérage sur une voie radiale, au moyen d'un dispositif de transport de feuilles (2,3,4,5) rotatif fixe, depuis la face intérieure, c.-à-d. la face concave de la voie de mouvement.
Patent CA-2409501-A1 (CA)
Inventor: MAULT JAMES R
IPC: G16H40/60
Filed: 2001-05-25
Abstract: A wrist-mounted device (50) for assisting a person to maintain a calorie balance goal comprises; a processor (10), a display (12), a barcode reader (20), input mechanisms for active (82) and resting states (00), a blood glucose sensor (20), and a communications network (250).
Patent CA-2411687-A1 (CA)
Title: Device for evaluating authenticity features that have a diffraction structure
Inventor: HOEPPNER HARALD
IPC: G06K19/16
Filed: 2001-05-25
Abstract: An apparatus for evaluating distinguishing authenticity features with diffraction structures on a document, which is placed on an examining surface of a examining device and illuminated by an illumination source, the distinguishing authenticity feature, which is to be examined, diffracting the beam of the illuminating source and projecting it on an evaluating unit in the device. In order to be independent of the nature and location of the diffraction pattern, which is to be evaluated, the diffraction pattern, derived from the document to be examined, is projected onto a projection surface. The projected diffraction image is covered and evaluated by a camera (matrix or cells).
Patent CA-2411892-A1 (CA)
Title: Coating composition
Inventor: SCHAFHEUTLE MARKUS A
IPC: C08G81/00
Filed: 2002-11-15
Abstract: Coating composition especially for preparing automotive surfacers, comprising a condensation product A of a carboxyl-containing resin A1 and a hydroxyl-containing resin A2, a curing agent C which becomes active only at an elevated temperature of at  least 80 °C, and a high molecular mass polyurethane B
Patent CA-2413441-A1 (CA)
Inventor: DIMAGGIO DOMINICK J
IPC: F28F17/00
Filed: 2002-12-03
Abstract: COMPACT HIGH EFFICIENCY      CLAM SHELL HEAT EXCHANGER        ABSTRACT OF THE DISCLOSURE A clamshell heat exchanger comprises upper and lower clamshell plates assembled together and sealed at the peripheral edges thereof, the assembled plates defining at least three internal passageways communicating in a serpentine configuration. The passageways include an inlet passageway having an inlet port for receipt therethrough of combustion gases, an intermediate passageway and an exhaust passageway having an exit port for the discharge of combustion gases, all such passageways lying generally parallel to each other. In one arrangement of the heat exchanger, the upper and lower clamshell plates define an air gap between the inlet passageway and the intermediate passageway, with the intermediate passageway and the exhaust passageway being joined by a secured flattened portion of the upper and lower clamshell plates. In another arrangement, instead of an air gap, the inlet passageway and the intermediate passageway are also joined by secured flattened portions of the upper and lower clamshell plates.Turbulent flow structure is provided by dimpled surfaces projecting inwardly into the intermediate and exhaust passageways and a longitudinally extending rib projecting into the intermediate passageway. A  drain shunt, defined by a generally tubular channel, communicates between the intermediate passageway and the exhaust passageway to allow drainage of condensation from the heat exchanger when the heat exchanger is disposed in any orientation.
Patent CA-2415547-A1 (CA)
Title: Process for preparing benzoxazin-4-one polymer conjugates
Inventor: FOSSUM RENAE DIANNA
IPC: A61K31/787
Filed: 2001-07-11
Abstract: The present invention relates to a process for forming polymer conjugates which are useful as enzyme inhibitors. The process of the present invention comprises the steps of:a) reacting a polymer or copolymer having the formula  (1) wherein R is a hydrocarbyl moiety, a polyalkyleneoxy moiety, or a heteroatom comprising hydrocarbyl moiety, said polymer or copolymer having a  molecular weight of from about 500 daltons, with phosgene to form a chloroformate having the formula (2); b) combining a substituted or unsubstituted anthranilic acid having the formula (3) wherein each R1 unit i s an enzyme interaction attenuating unit; and a base catalyst wherein said bas e catalyst is a supported base catalyst, to form a substrate reactive admixtur e; and c) adding to said chloroformate formed in step (a) said substrate reacti ve admixture formed in step (b) to form a benzoxazin-4-one conjugate having the  formula (4).
Patent CA-2418496-A1 (CA)
Inventor: BANVILLE STEVEN C
IPC: C12N15/12
Filed: 2001-02-01
Abstract: The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM  antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.
Patent CA-2419935-A1 (CA)
Title: Collagen/polysaccharide bilayer matrix
Inventor: LIU LIN SHU
IPC: A61K48/00
Filed: 2001-08-10
Abstract: Disclosed are bilayer matrices of a polysaccharide such as collagen (COL) and another polysaccharide such as hyaluronic acid (HA) with various COL/HA  ratios. Each layer has a porous structure. These materials are useful for tissue regeneration, particularly when used with orthopedic implants and drug delivery.
Patent CA-2420459-A1 (CA)
Inventor: MCCALL CATHERINE A
IPC: A61K31/7052
Filed: 2001-09-14
Abstract: The present invention relates to high molecular weight Dermatophagoides proteins, nucleic acid molecules encoding such proteins, and therapeutic and  diagnostic reagents derived from such proteins.
Patent CA-2420493-A1 (CA)
Title: Use of carnitine for enhancing training-induced bradycardia
Inventor: VERVUERT INGRID
IPC: A23K1/18
Filed: 2001-09-18
Abstract: Use of Carnitine for achieving or enhancing training-induced bradycardia in a mammal, particularly in a horse, most preferably in a trotter horse.
Patent CA-2420774-A1 (CA)
Inventor: PINEDA FERNANDO J
IPC: H01J49/40
Filed: 2001-09-25
Abstract: A method for calibrating time-of-flight mass spectrometers is provided. The method includes at least modeling a time-of-flight mass spectrometer as a composite operator in accordance with a state space approach. The model is used to perform both symbolic and numeric propagation. To perform symbolic propagation, the model is used to derive closed form equations for the time-of-flight, by symbolically propagating the state of one or more ions modeled as state vectors. To perform numeric propagation, the model is used to calculate the time-of-flight by numerically propagating the state vector representation of one or more ions.
Patent CA-2426704-A1 (CA)
Title: Process for producing hydrogen peroxide
Inventor: JONES C ANDREW
IPC: B01J23/52
Filed: 2001-11-13
Abstract: A supporting gold-containing catalyst is effective for producing hydrogen peroxide from the direct liquid-phase reaction of hydrogen and oxygen.
Patent CA-2427248-A1 (CA)
Title: Ensemble de trepans interchangeables
Inventor: NACKERUD ALAN L
IPC: E21B10/34
Filed: 2001-10-24
Abstract: L'invention concerne un ensemble de trépans récupérables dans lequel un tube de forage ou tube de revêtement standard (10) comporte une réduction de tiges (11) vissée dans l'extrémité inférieure dudit tube, ladite réduction de tiges formant un couplage de siège pour des extrémités pivotantes arrondies supérieures d'une paire de trépans (12) montée de manière pivotante entre une paire de plaques de levage (20). Les trépans comportent des lames (16) s'étendant à partir des extrémités pivotantes (14). Lesdites lames présentent des éléments coupants trempés (28, 24) disposés de manière décalée le long ou à côté du bord d'attaque, et un passage fluidique (34, 35) aboutissant dans une série de tuyères (38) dans les lames, lesdites tuyères, la force de rotation du tube de forage, ainsi que la force de friction des lames sur le matériau à forer amenant les lames en position perpendiculaire l'une par rapport à l'autre. Les lames ou éléments coupants peuvent être récupérés au moyen d'un dispositif de récupération (50, 56) de manière à les remplacer par un nouvel ensemble de lames.
Patent CA-2429224-A1 (CA)
Title: Inhalation of nitric oxide
Inventor: CHEN LUNI
IPC: A61K45/06
Filed: 2001-11-15
Abstract: Use of inhalable gaseous nitric oxide (NO) in combination with a cyclooxygenase inhibitor for the manufacture of a medicament for treating pulmonary vasoconstriction or airway constriction in a mammal, including man, in order to counteract a hypo- or non- response to treatment with gaseous nitric oxide or nitric oxide donor only and/or to counteract a rebound response in the case of withdrawal of treatment with gaseous nitric oxide or nitric oxide donor only said combination being use in a therapeutically effective amount to accomplish relaxation of said pulmonary vasoconstriction or airway constriction. A method and a pharmaceutical preparation for the treatment of pulmonary vasoconstriction or airway constriction while using the above-mentioned combination.
Patent CA-2429583-A1 (CA)
Inventor: ROZEN RIMA
IPC: C12Q1/68
Filed: 2001-12-03
Abstract: L'invention concerne des inhibiteurs de la méthylènetétrahydrofolate réductase (MTHFR), utiles dans l'inhibition sélective de la croissance cellulaire cancéreuse, chez un mammifère. Ces inhibiteurs peuvent être une petite molécule, un oligonucléotide antisens, un ribozyme, un oligonucléotide formant une hélice triple, un anticorps dirigé contre la MTHF réductase, ou un fragment de cet anticorps, un mutant ou un fragment de la MTHF réductase. L'invention concerne en outre des acides nucléiques codant pour un inhibiteur de la MTHF réductase, ainsi que des vecteurs comprenant ces acides nucléiques. L'invention porte également sur des procédés d'utilisation des inhibiteurs de la MTHF réductase, aux fins d'inhibition sélective de la croissance cellulaire cancéreuse, de même que sur des compositions pharmaceutiques comprenant ces inhibiteurs.
Patent CA-2431564-A1 (CA)
Inventor: SMITH ROBERT B
IPC: G01C17/38
Filed: 2001-12-04
Abstract: A three-axis physical model is used to numerically compensate for errors in measured magnetic field values in an electronic compass for operation on any orientation. This compensation method generates certain quantities that characterize the magnetic field of the Earth in the vertical plane.  These quantities are used to monitor the accuracy of the electronic compass during normal operation by comparing their current values either with values obtained during the calibration procedure or with values obtained from historical averages.  Significant departure from the calibration values or from the historical averages indicates a probable loss of accuracy of the compass, and the user is so alerted.
Patent CA-2432210-A1 (CA)
Title: Scanning spectrophotometer for high throughput fluorescence detection
Inventor: GOULD GENE
IPC: G01J3/18
Filed: 2001-12-31
Abstract: A fluorescence spectrophotometer system may be implemented in scanning fluorescence polarization detection applications. A wavelength and area scanning fluorescence spectrophotometer system may include a light source, an excitation double monochromator, an excitation/emission light transfer module, an emission double monochromator, a high speed timer-counter circuit board, a precision positioning apparatus for positioning a sample relative to the focal plane of the excitation light, and polarizing filters at the excitation side and the emission side. The system may be operative to analyze more than one fluorescent compound in the sample; additionally or alternatively, the system enables analysis of samples from selected ones of a plurality of samples.
Patent CA-2434472-A1 (CA)
Title: Gelling vegetable protein
Inventor: SINGH NAVPREET
IPC: A23L13/40
Filed: 2002-01-15
Abstract: A process to obtain a highly soluble, low viscosity, salt tolerant gelling vegetable protein product. When introduced into a suitable meat injection brine, the protein product is capable of forming a firm sliceable meat piece with high water retention and no visible signs of the injected brine. When included in gel-based food products such as meat analog formulas, the protei n product is capable of forming the desired gel structure, such as firm, sliceable meat-like pieces.
Patent CA-2438704-A1 (CA)
Inventor: KOEGEL BABETTE-YVONNE
IPC: A61K31/166
Filed: 2002-02-20
Abstract: L'invention concerne des dérivés substitués de propane-1,3-diamine de formule générale (I), des procédés de production de ces dérivés, des médicaments et des compositions pharmaceutiques les contenant, ainsi que leur utilisation dans la préparation de médicaments destinés au traitement thérapeutique et/ou prophylactique de la douleur, de l'incontinence urinaire, de démangeaisons, du tinnitus auriculaire et/ou de la diarrhée.
Patent CA-2439396-A1 (CA)
Inventor: DEMOPULOS GREGORY
IPC: G06Q10/00
Filed: 2001-02-23
Abstract: Results of medical test for sexually transmissible diseases (STDs) or other medical conditions such as drug use are posted to registry site (112) accessible by subscriber and subscriber-authorized guests (120). Medical test results are associated with subscriber identity verification (108), which may be a driver's license number, or other indicia of identification, recorded when a test sample was drawn by a testing lab affiliated with the registry site (104). Results of the test performed by the testing lab are automatically posted to the registry site (112), along with subscriber's pre-assigned customer ID (100) and verification of subscriber's identity (104).  Subsequently, subscriber and authorized guests can access the subscriber's test results (120) and the verification of the subscriber's identity by entering a predefined password or other access code, thereby enabling the guest, who may be a prospective sexual partner, to verify a medical condition asserted by the subscriber (122).
Patent CA-2439583-A1 (CA)
Title: Intravascular filter system
Inventor: SEGUIN JACQUES
IPC: A61B17/22
Filed: 2002-03-04
Abstract: A removable intravascular filter system traps emboli and other solid materials in connection with intravascular medical procedures such as the placement of a stent or a catheter balloon. The system involves a hollow guidewire and an actuating wire movable within the guidewire to actuate the filter membrane.  Embodiments of the filter system include biased closed and biased open filter configurations, and are easily routed through a patient's artery and deployed.  Optionally, the actuating wire can be removed and a substitute wire can be inserted into the hollow guidewire. Control mechanisms can help the operator limit movement of the actuating wire during deployment and/or collapse of the filter membrane. Preferred filter membranes are configured to maximize both blood flow and emboli capture.
Patent CA-2442080-A1 (CA)
Title: A preparation for restenosis prevention
Inventor: SPECK ULRICH
IPC: A61P35/00
Filed: 2001-12-20
Abstract: The invention relates to a preparation for the prophylaxis of restenosis.  Sufficient active ingredient concentration in the relevant areas of the blood vessel walls cannot be achieved with preparations for the prophylaxis of restenosis known in prior art due to the fact that higher doses cause side effects. According to the invention, at least one lipophilic, anti-hyperplastic active ingredient having a distribution coefficient between butanol and water of >= 0.5 is added to a preparation. A sufficient amount of the lipophilic active ingredient is rapidly absorbed in the blood vessel wall.  The preparation can be liquid or distributed by capillarity and can contain a contrast medium so that passage of active ingredients to the blood vessels occurs without further complications as is normally required in contrast images. The preparation can also be applied on a catheter.
Patent CA-2444105-A1 (CA)
Inventor: SCHULZ MICHAEL
IPC: G11B7/244
Filed: 2002-04-09
Abstract: La présente invention concerne des mélanges de phthalocyanines de métallocényle, obtenus par mise en réaction d'un mélange A comprenant deux phthalocyanines (I) et (II) avec un dérivé de métallocène, en présence d'un catalyseur, ainsi que des phthalocyanines de métallocényle oligomériques, des procédés pour les préparer, leur utilisation, entre autres, dans le domaine de l'enregistrement optique et des supports d'enregistrement optique.
Patent CA-2444457-A1 (CA)
Title: Method of improving plant growth
Inventor: BAPTIST JAMES N
IPC: C05F15/00
Filed: 2002-07-15
Abstract: A method of improving plant growth by providing controlled amounts of precursor solutions of either new or used ethylene glycol (antifreeze), an emulsified used motor oil, other biodegradable material to the soil to produce carbon dioxide by the action of soil microorganisms. Also, shredded paper can be added to the soil.
Patent CA-2444662-A1 (CA)
Title: Stable herbal dentifrice
Inventor: XU JIN
IPC: A61K8/55
Filed: 2002-04-19
Abstract: A dentifrice gel or paste comprising from about 40% to 70% by weight baking soda, from about 0.5% to 5% by weight of a blend of natural ingredients, fro m about 0.5% to 5% by weight of a flavoring oil and a sufficient amount of a stabilizing combination of a xanthan gum binder, at least one betaine surfactant and ahumectant comprising glycerin or glycerin and sorbitol in an amount sufficient to render the dentifrice formulation stable to degradation and resistant to syneresis and phase separation.
Patent CA-2448881-A1 (CA)
Title: Sugar and lipid metabolism regulators in plants ii
Inventor: CIRPUS PETRA
IPC: A01H5/00
Filed: 2002-06-04
Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metaboli sm regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. T he nucleic acids and proteins are used in methods of producing transgenic plant s and modulating levels of seed storage compounds. Preferably, the seed storag e compounds are lipids, fatty acids, starches or seed storage proteins.</SDOAB >
Patent CA-2451485-A1 (CA)
Title: Method and apparatus for recordable media content distribution
Inventor: RODRIGUEZ ARTURO A
IPC: H04N21/472
Filed: 2002-06-26
Abstract: A media system (10) which includes logic configured to provide a user interface that provides a user with a plurality of media content selection available at various times, and a portable client media drive (16) configured to receive over a secured transmission medium the media content by the user.
Patent CA-2453354-A1 (CA)
Title: Sports surface reconditioner
Inventor: JOMPHE JULIEN
IPC: E01C23/088
Filed: 2004-01-08
Abstract: A device for reconditioning a damaged sports surface. The device includes at least one rotatably driven shaft with two ends, one of which is connected to a frame, the other end being disposed towards the surface. The driven shaft is disposed orthogonal relative to the surface. A work head is connected to the shaft and is in contact with the surface. The work head is rotated by the shaft relative to the surface and reconditions the surface. A mobile device is disclosed.
Patent CA-2454492-A1 (CA)
Title: Client side rendering of printable documents in a network
Inventor: LAWRENCE MARK A
IPC: G06F3/12
Filed: 2003-12-30
Abstract: In a network facilitating print functions, a means for rendering a print job intended for a remote printer on a client computer using stored administrative settings is provided. Transparently to the client's applications, the client computer keeps the stored remote printer's administrative settings synchronized with those stored on the print server. Using the stored administrative settings, the client renders the print job to a native printer language directly cognizable by the printer before sending this rendered file to the print server for forwarding to the printer. By queuing these remote print jobs, the online status of the respective print server is also transparent to the client's applications, facilitating off-line printing.