baber/WOPTO huggingface dataset:
Patent PT-742250-E (PT)
Inventor: KRUCKE WERNER
IPC: C08J9/14
Filed: 1996-05-03
Abstract: The prodn. of flexible foam comprises reacting di- or poly- isocyanates with cpds. contg. at least two NCO-reactive H atoms in the presence of a blowing agent (II) and opt. other additives. (II) is a mixt. contg. 1,1,1,2-tetrafluoroethane (TFE) and at least one other cpd. selected from 1,1-difluoroethane (DFE) and readily volatile organic cpds. with a b.pt. below 105 (pref. below 80) degrees C, i.e. ketones, acetates, aliphatic and cyclic hydrocarbons, halogenated hydrocarbons or N-contg. hydrocarbons. Also claimed is a blowing agent compsn. (II) for this process, contg. 50-95 wt% TFE and 5-50 wt% DFE and/or other cpds. as above Pref. compsn. (II) contains 50-95 pts. wt. TFE and 5-50 pts. wt. other blowing agents, pref. 50-95 pts. wt. TFE and 5-50 pts. wt. of a mixt. of DFE and other volatile cpds. with a b.pt. below 80 degrees C, or a mixt. of 84-88 wt% TFE and 12-16 wt% DFE.
Patent PT-805803-E (PT)
Inventor: BRIEDEN WALTER
IPC: C07D241/06
Filed: 1996-01-19
Abstract: 1,4,5,6-tetrahydropyrazine-2-carboxamides of formula: wherein R1 is hydrogen, alkyl, cycloalkyl or arylalkyl; R2 is alkyl, aryl, or arylalkyl and R3, R4 and R5 are hydrogen, acyl, aryl or arylalkyl or R2 forms an alicyclic system with R3 or R4 and the adjacent carbon atom(s), R6 being hydrogen or a group of formula R7-C(=O)- wherein R7 is hydrogen or alkyl. These compounds can be used in the production of piperazine carboxamides.
Patent PT-824356-E (PT)
Inventor: BOMPARDELLI EZIO
IPC: A61K31/343
Filed: 1996-05-08
Abstract: PCT No. PCT/EP96/01916 Sec. 371 Date Nov. 10, 1997 Sec. 102(e) Date Nov. 10, 1997 PCT Filed May 8, 1996 PCT Pub. No. WO96/35441 PCT Pub. Date Nov. 14, 1996The invention discloses to methods for preparing and using a lipophilic extract of the roots of Salvia miltiorrhyza Bunge for treating drug addiction. The Tanshinone IIA and Miltirone components of such lipophilic extracts are preferably used individually or in combination to treat drug addictions, and in particular, to treat alcohol addiction.
Patent PT-800166-E (PT)
Inventor: CESHKOVSKY LUDWIG
IPC: G11B7/13
Filed: 1997-03-19
Abstract: An apparatus is disclosed for control of a beam of radiant energy, wherein a detector of the beam has first and second outputs responsive to a position of the beam. A circuit is coupled to the outputs of the detector for producing an error signal representing a displacement of the beam from a predetermined position, wherein the error signal has a periodic characteristic relative to the displacement. A servo responsive to the error signal restores the displaced beam to the predetermined position. A local feedback loop is coupled to the outputs of the detector, and includes first and second periodic function generators, each responsive to the error signal. The second periodic function generator has an output that differs from an output of the first periodic function generator by a phase angle, preferably 90 degrees. A first multiplier multiplies the first output of the detector by the output of the first periodic function generator. A second multiplier multiplies the second output of the detector by the output of the second periodic function generator, wherein the outputs of the first and second multipliers are provided as inputs of the circuit to modify the error signal. <IMAGE>
Patent PT-882704-E (PT)
Inventor: SAITO MAMORU
IPC: C07D295/185
Filed: 1997-02-18
Abstract: 3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives represented by general formula (1) and their pharmacologically acceptable salts having a selective  beta 2-adrenergic receptor stimulating effect with a relieved burden on the heart such as a frequent pulse. In said formula, A represents lower alkylene; B represents amino, di(lower alkyl)amino or 3- to 7-membered alicyclic amino optionally containing oxygen in the ring; n is an integer of 1 or 2; the carbon atom marked with "*" means a carbon atom or the R- or S- configuration or a mixture thereof; and the carbon atom marked with "(S)" means a carbon atom of the S-configuration. These compounds are useful as a preventive for threatened abortion/premature birth, a bronchodilator and a pain-relieving and lithagogue agent in ureterolithiasis. <CHEM>
Patent PT-947513-E (PT)
Inventor: KIMURA KENICHI
IPC: C07D498/04
Filed: 1997-10-23
Abstract: The present invention relates to a compound having a tricyclic amine substituent which may have various substituents, the compound being represented by formula (I), a salt or hydrate thereof, and a hydrate of the salt and a drug containing them as an active ingredient. They exhibit excellent antimicrobial activity against Gram negative bacteria and Gram positive bacteria with a satisfactory fate and safety and are useful in the treatment of infectious diseases. <CHEM>     wherein Q preferably represents the following partial structure which may have various substituents: <CHEM> o
Patent PT-889044-E (PT)
Inventor: REITZ ALLEN B
IPC: A61K31/435
Filed: 1998-06-29
Abstract: A compound of the general formula 1; <CHEM> is disclosed as useful in treating disorders of the central nervous system. Pharmaceutical compositions and methods of treatment are also disclosed.
Patent PT-987323-E (PT)
Inventor: ATHANASIOS NIKOLAOU
IPC: C12C7/04
Filed: 1998-08-21
Abstract: The quality improvement of alcoholic beverages, is achieved by vibrated emission towards the alcoholic beverages (1) of electromagnetic waves (6), produced by electromechanical or electric devices (3), with predetermined programming, covering wider wavelength bands from 1 nm to 10000 Km, with the harmonic frequencies produced by the device, which are emitted simultaneously, either in all wavelengths from 1 nm to 10000 Km, or to one or more parts of specific frequencies, with controlled power, controlled time of application and controlled quality result. The invention belongs to the field of the electronic science, in combination to the science of food and drink technology and can be applied on final or not, alcoholic beverages (1), notwithstanding the kind of their storage or get up material (2), in industries, handicrafts, commercial undertakings, as well as domestically. <IMAGE>
Patent PT-1007006-E (PT)
Inventor: REMON JEAN PAUL LOUIS AUGUSTE
IPC: A61K9/00
Filed: 1998-03-19
Abstract: This invention relates to uncoated direct compression tablets containing cefadroxil monohydrate as the active ingredient, which are capable of oral administration to human beings by swallowing, chewing or disintegrating in water resulting in a drinkable dispersion.
Patent PT-1070015-E (PT)
Inventor: BENSLEY DOUGLAS S
IPC: B67D1/04
Filed: 1999-04-06
Abstract: A liquid dispenser and control system includes a base member having an intake cavity with an axis for orientation in an upward direction, the intake cavity being sealingly mateable with a mouth opening of a replaceable liquid container which, when mated with the intake cavity, is in an inverted position for draining liquid through the mouth opening into the intake cavity. The intake cavity includes a sump into which liquid from the container can drain by gravity. The vent tube assembly has an intake end connectable to atmosphere or a source of gas, the vent tube assembly extending from the base member through the intake cavity, and has a venting end for positioning inside the container. A passageway extends through a portion of the base member, the passageway having an entry end and an exit end, the entry end connected to the sump, through which liquid from the sump can drain into the passageway. A sensor has a fluid path therethrough connected to the exit end of the passageway, the sensor for detecting when liquid flow through the passageway from the container ceases and is followed by gas from the container entering the sensor. A liquid conduit is connected to the fluid path of the sensor, for receiving liquid passing through the sensor.
Patent PT-1102594-E (PT)
Inventor: TOUTAIN HERVE
IPC: A61K33/00
Filed: 1999-08-03
Abstract: Use of sodium chloride for preparing an agent intended to reduce or eliminate the gastrointestinal side effects induced by the administration of camptothecin derivatives, characterized in that the sodium chloride solution is administered orally.
Patent PT-1220817-E (PT)
Inventor: MOFFETT ROBERT HARVEY
IPC: B01J13/00
Filed: 1999-09-13
Abstract: Silica deposits formed during a continuous process for preparing polysilicate microgel are removed and purged form the process by elastically deforming the vessel walls, reducing plugging.
Patent IE-810186-L (IE)
Title: Non-staining antigingivitis composition
IPC: A61P1/02
Filed: 1981-01-30
Abstract: A non-antibacterial oral composition effective to promote oral hygiene containing tranexamic acid as antigingivitis agent and an additive which reduces staining of dental surfaces caused by said agent without substantially diminishing the antigingivitis activity of said agent. The antistain additive is a peroxydiphosphate salt, preferably tetrapotassium peroxydiphosphate (K4P2O8).
[US4309410A]
Patent IE-34075-L (IE)
Title: Antibiotic compositions
IPC: A61K47/00
Filed: 1970-03-12
Abstract: 1,250,304. Stable oxytetracycline compositions. DIAMOND SHAMROCK CORP. 12 March, 1970 [13 March, 1969; 4 Feb., 1970], No. 11937/70. Heading A5B. [Also in Division C2] Stable, injectable antibiotic compositions for parenteral administration comprise (a) 0.1 to 15 parts by weight of oxytetracycline base or an acid addition salt thereof, (b) a watersoluble magnesium salt present in a molar ratio of 0.5 to 2 moles per mole of the antibiotic, (c) 50 to 95 parts by weight of a glycerol formal selected from 4-hydroxymethyl-1,3- dioxolane and/or 5-hydroxy-1,3-dioxane, (d) 0 to 45 parts by weight of water, (e) an antioxidant in an amount sufficient to stabilize the composition, and (f) a buffering agent in an amount sufficient to impart a pH of 6 to 9.5 to the composition. Component (a) may be oxytetracycline hydrochloride, phosphate, sulphate or acetate; component (b) may be magnesium chloride, acetate, sulphate, gluconate, glucoheptonate or phosphate; component (e) may be sodium bisulphite, metabisulphite or formaldehyde-sulphoxylate; and component (f) may be sodium hydroxide, potassium carbonate, ammonia, ethanolamine, diethylamine, ethylamine, triethanolamine, diethanolamine, arginine or glucosamine. The compositions may also contain ethanol.
[GB1250304A]
Patent IE-900686-L (IE)
Title: Process for preparing extruded foam bodies
IPC: B29C48/90
Filed: 1990-02-26
Abstract: A process for preparing an extruded thermoplastic resin elongate foam body comprising an alkenyl-substituted aromatic resin is described. The process comprises the steps of     (A) heat plastifying the thermoplastic resin; (B) adding at least one fluid blowing agent comprising at least one of 1-chloro-1,1-difluoroethane, 1,1,1,2-tetrafluoroethane and 2-chloro-1,1,1,2-tetrafluoroethane; (C) uniformly mixing the blowing agent in the resin under a pressure sufficient to prevent blowing of the resin thereby forming a blowable resin mixture; (D) extruding the mixture into a region of reduced pressure which is less than atmospheric pressure wherein the blowable resin mixture expands into a foam body; and   (E) cooling the foam body. o
Patent IE-39485-L (IE)
Title: Mine roof reinforcing bolt.
IPC: E04C5/12
Filed: 1974-03-29
Abstract: 1425791 Anchoring bolts ACIERIES REUNIES DE BURBACH-EICH-DUDELANGE SA 2 April 1974 [2 April 1973] 14668/74 Heading F2H To reinforce the material of, e.g. a mine roof, a bore formed in the material is partly filled with the reactive components of a bonding agent, a bolt 1 roughened at its leading end 2 and threaded at its rear end 4, with a nut 5 held captive on the threaded portion 4 by a discontinuity 6 in the thread, is inserted in the bore and, to stir and mix the bonding agent components, is rotated in a direction tending to unscrew the nut from the bolt by rotation of the nut so that the nut backs on to the thread discontinuity 6, allowing the bonding agent to harden, rotating the nut 5 in the opposite direction until it bears on the surface of the material being reinforced, and continuing rotation of the nut to prestress the bolt and the surrounding material. As shown, a second nut 7 on the part of the threaded portion 4 to the rear of the discontinuity 6 enables a load to be attached to the bolt. The roughened portion 2 is a coarse screw thread of the same hand as the thread 4. A washer or bearing plate 8 is provided ahead of the nut 5. Preferably the bonding agent components are separately packaged in rupturable cartridges or bags which are pierced by teeth 3 or a point at the tip of the bolt. If the second nut 7 is not required, the discontinuity may be formed at the rear end of of the bolt by hammering.
[GB1425791A]
Patent IE-34292-L (IE)
Title: Cardenolide glycosides
IPC: C07J19/00
Filed: 1970-06-09
Abstract: 1320361 22-Substituted cardenolide glycosides DR KARL THOMAE GmbH 10 June 1970 [10 June 1969] 28196/70 Heading C2U [Also in Division C3] The invention comprises compounds of formula wherein R 1 is H, OH, acyloxy, 2<SP>1</SP>-tetrahydropyranyloxy or trimethylsiloxy; X is F, Cl, C 1-4 alkyl or C 1-4 alkoxy; and A is a group of formula wherein R 2 is H, acyl, 2<SP>1</SP>-tetrahydropyranyl or trimethylsilyl. Preparation thereof is by base-catalysed intramolecular cyclization of compounds of formula wherein R<SP>1</SP> 1 is H or protected hydroxy; X is as defined above; A<SP>1</SP> is a group as defined above for A wherein R 2 is a hydroxyl-protecting group; and R 3 is C 1-4 alkyl. When the resultant product contains a hydroxyl-protecting group other than acyl, 2<SP>1</SP>-tetrahydropyranyl or trimethylsilyl (e.g. benzyl), then said group must be removed to give a compound of Formula I. Removal of protecting groups in general may be effected by acid or base hydrolysis or by hydrogenolysis. A free hydroxyl group (R 1 or OR 2 ) in the product may thereafter be acylated. The starting materials are prepared as described in Specification 1,320,362. The inventive compounds are said to be cardioactive, and may be made up with carriers into pharmaceutical compositions for oral, rectal and parenteral administration.
[GB1320361A]
Patent IE-44929-L (IE)
Title: Fabric permeable to uv radiation
IPC: D01D5/00
Filed: 1977-05-04
Abstract: This invention relates to a fabric made from a polymer or of a miXture of polymers having an absorption curve of radiating energy characterized by a minimum absorption between 3,200 A and 4,000 A and an important filtering below 3,200 A, said polymer being eXtruded at a speed allowing an eXtremely quick cooling such that the formation of large crystallites is inhibited while promoting proliferation of crystallites of very small sizes.
[US4115615A]
Patent IE-39702-L (IE)
Title: Back-flow and odour trap for liquids
IPC: E03C1/298
Filed: 1974-05-06
Abstract: 1444053 Valves A KLENK and H KLENK 10 May 1974 [10 May 1973 25 July 1973] 20867/74 Heading F2V [Also in Division E1] A valve trap includes a vertical inlet pipe 8 closable at its lower end by a valve 14 in the form of a pan 17 pivotal about a horizontal axis 12 and biased by a counterweight 16 to a closed position in which its rim co-operates with a seal 16a disposed around the pipe, the bottom of the pan rising from the pan's deepest point in a straight line to an overflow edge and the pan, pivot axis and counterweight lie substantially in a common plane. The lower end 9 of the pipe terminates above the level of water necessary in the pan to open the valve. The pipe 8 leads to a galley 1<SP>1</SP> having an outlet 30 with a float valve 31 forming an odour seal. The valve 31 may be closed by a screw arrangement 37 which presses a stirrup 35 on to the float. The bottom of the pan is a double wall defining a hollow chamber 22.
[GB1444053A]
Patent IE-45066-L (IE)
Title: Dyeing hair
IPC: A61K8/00
Filed: 1977-05-26
Abstract: Some people want the colour of their hair to change gradually over the course of a few weeks rather than abruptly. To this end, the procedure involves a series of successive dyeings giving an increasingly intense coloration. Oxidation dyes are used, the amount of dye solution being the same for all the dyeings but the amount of oxidising agent, which is limited to the stoichiometric amount for the first dyeing, being gradually increased in the successive dyeings until the desired final hue is obtained, the latter then being maintained by repeating the final treatment as required.
[GB1542034A]
Patent IE-33399-L (IE)
Title: Aliphatic acids; ester separation
IPC: C07C67/58
Filed: 1969-10-07
Abstract: 1282926 Esterification and extraction EL PASO PRODUCTS CO 7 Oct 1969 [10 Oct 1968 19 Aug 1969] 49255/69 Heading C2C In a process for the separation of esterifiable aliphatic carboxylic acids admixed in aqueous solutions, the mixture is (a) contacted with an alkyl alcohol (1-5 C), alkylene glycol, or their ether derivatives at from 25 degrees to B.P. in the presence of an esterification catalyst and (b) simultaneously and countercurrently contacted with a water-immiscible organic solvent to extract the esters as formed, (c) partitioning to an organic phase containing at least a portion of the esters and an aqueous phase containing excess water-miscible solvent, unesterified organic acids and water, (d) layering out and separating the two phases, (e) distilling the organic phase to recover the solvent and the esters and (f) distilling the aqueous phase to recover any excess water-miscible solvent and the residue. The aqueous solution may be mixtures of at least two monocarboxylic, saturated or unsaturated, substituted or unsubstituted acids, a dicarboxylic acid which is saturated or unsaturated substituted or unsubstituted, and tri- or polycarboxylic acids and many are listed, for example, the mixed acids obtained by the nitric acid oxidation of cyclohexanol and cyclohexanone, and of fats and fatty acids; the oxidation of paraffins; the hydration of maleic acid; the fermentation processes yielding lactic, oxalic or citric acids; and carbohydrate degradation processes yielding levulinic acid. The water-immiscible solvents may be aliphatic, cycloaliphatic and aromatic hydrocarbons and halogenated aliphatic or aromatic hydrocarbons. The process is illustrated using apparatus comprising a series of three feed tanks, three extractors and two settlers to provide a continuous system. Examples describe the extraction of dimethyl esters of mixed succinic, glutaric and adipic acids from the nitric acid oxidation of cyclohexanol and cyclohexanone, and the nitric acid oxidation of cyclohexane; esters from oleic and tall oil oxidation acids; mixed maleic and cyanacetic acid esters, esters from mixed oxalic, malonic, succinic, glutaric and alipic acids, esters of mixed acids from the hydration of maleic acid; esters of technical grade aconitic, lactic and levulinic acids and of the acids derived from the hydrolysis of sucrose.
[GB1282926A]
Patent IE-851683-L (IE)
Title: Morphinanesters
IPC: C07D489/08
Filed: 1985-07-04
Abstract: Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans are useful as analgesics or narcotic antagonists and provide enhanced bioavailability of 3-hydroxymorphinans from orally administered doses.
[US4668685A]
Patent IE-902139-L (IE)
Title: Imidazolyl alkenoic acids
IPC: A61P27/02
Filed: 1990-06-13
Abstract: Angiotensin II receptor antagonists having the formula: <CHEM> which are useful in requlating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mamnals.
[EP0403158A2]
Patent IE-892296-L (IE)
Title: SELECTIVE ENZYMATIC DEGRADATION OF ß-LACTOGLOBULIN CONTAINED¹IN COW'S MILK-SERUM PROTEIN
IPC: A23J3/34
Filed: 1989-07-14
Abstract: This invention relates to a method of selectively degrading beta -lactoglobulin contained in cow's milk-serum protein by using a specific enzyme capable of selectively degrading beta -lactoglobulin.
[EP0355399A1]
Patent IE-46052-L (IE)
Title: Preparation of a latex-silica masterbatch
IPC: C08L7/00
Filed: 1977-11-28
Abstract: Silica plastic compositions containing a silicate filler finely dispersed therein are produced by simultaneously adding a mixture of an aqueous solution of an alkali silicate and a coagulable latex emulsion of a plastic polymeric material and a solution of at least one salt of hydrochloric or sulfuric acids and a metal selected from the group consisting of zinc, magnesium, calcium, and maintaining the pH of the reaction medium at a level appropriate for the precipitation of the neutral silicate of the metal, yet at which precipitation of either hydroxy salts of the metal or of alkaline silicates is substantially precluded. (From US4185001 A) [FR2372192A1]
Patent IE-892448-L (IE)
Title: The use of imexon as an immune suppressive and¹pharmaceutical compositions containing imexon
IPC: A61K31/415
Filed: 1989-07-27
Abstract: The present invention relates to the use of 4-imino-1,3-diazabicyclo[3.1.0]hexan-2-one (imexon) as an immunosuppressive agent. Imexon selectively suppresses  beta -lymphocyte activation and can be employed for the treatment of B-cell or plasma-cell leukaemia and neoplasms. Imexon is used in the treatment of those disorders in which polyclonal B-cell proliferation is of pathophysiological, symptomatic or clinical relevance such as, for example, for autoimmune diseases.
Patent IE-40559-L (IE)
Title: Substrate for determining a proteinase.
IPC: C12Q1/37
Filed: 1974-12-20
Abstract: 1496907 Determination of proteinase BEHRINGWERKE AG 23 Dec 1974 [21 Dec 1973] 55521/74 Heading G1B [Also in Division C3] A method of determining proteinase comprises incubating the proteinase with a substrate com- prising a protein covalently bound to a solid carrier and having a reactive dyestuff covalently bonded to the protein [see Division C3], removing any undergraded substrate by filtration or centrifugation, measuring the absorption of the filtrate or centrifugate at a wavelength or wavelengths determined by the absorption characteristics of the reactive dyestuff, and calculating the activity of the enzyme therefrom.
[GB1496907A]
Patent IE-812671-L (IE)
Title: Hypocholesterolemic fermentation products
IPC: C12P7/62
Filed: 1981-11-16
Abstract: Substance isolated after cultivation of a microorganism belonging to the genus Penicillium and particularly in a Pencillium citrinum (ATCC 20606) culture medium comprising compounds which have the structures 
<CHEM>
 
<??>Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesterolemic and hypolipemic medicaments.
Patent IE-822721-L (IE)
Title: Cephalosporin derivatives
IPC: C07D501/36
Filed: 1982-11-15
Abstract: The present invention relates to new cephalosporins of general formula    <IMAGE>  (II)  in which R1=R2=CH3 or R1 and R2 together form a 1,3-propylene group, A is H, a cation, an ester or a hemiacetal, and R3 is a heterocycle comprising five or six atoms including at least one atom in the ring of nitrogen. It also relates to a process for preparing these cephalosporins and to the drugs containing them.