baber/WOPTO huggingface dataset:
Patent WO-2023081109-A1 (WO)
Title: Tailored hypoimmune nanovesicular delivery systems for cancer tumors, hereditary and infectious diseases
Inventor: MALCOLM THOMAS
IPC: A61K9/50
Filed: 2022-10-31
Abstract: Hypoimmunogenic induced pluripotent stem cell (iPSC)-derived biomimetic nanovesicles (Hypo-BioNVs) or Hypo-exosomes including tailored chimeric antigen receptor (CARs) which can recognize target biomarkers. A method of making Hypo-BioNVs. A method of treating an individual with cancer, by administering the Hypo-BioNVs to an individual, targeting cancer cells, and treating the cancer. Hypo-BioNVs including tailored CARs which can recognize target biomarkers through a VERR including viral receptors of an oncolytic virus. A method of treating an individual with cancer, by administering Hypo-BioNVs including CAR receptors to an individual, targeting cancer cells, and treating the cancer. A method of targeting cells in an individual, by administering the Hypo-BioNVs to an individual, and targeting cells to be destroyed or treated for cancer tumors (both liquid and solid), infectious disease, hereditary conditions, autoimmune disease, or metabolic disorders.
Patent WO-2023081330-A1 (WO)
Inventor: NAWANA NAMAL
IPC: A61B5/15
Filed: 2022-11-04
Abstract: L'invention concerne un timbre dermique pour collecter un échantillon physiologique, comprenant un boîtier avec une chambre de collecte, un canal d'échantillon et une broche à l'intérieur d'un réceptacle du boîtier. Le canal d'échantillon est configuré pour diriger un échantillon physiologique tiré d'un sujet vers la chambre de collecte. La broche est positionnée de manière amovible à l'intérieur du réceptacle et est configurée pour se déplacer d'une position non déployée à une position déployée. La broche est configurée pour sceller le réceptacle lorsqu'elle est dans la position non déployée et est en outre configurée pour faciliter la génération de pression négative dans le canal d'échantillon lorsque la broche est déplacée de la position non déployée à la position déployée.
Patent WO-2023107689-A1 (WO)
Title: Methods for treating primary immunodeficiency
Inventor: TAVERAS ART
IPC: A61K31/437
Filed: 2022-12-09
Abstract: The present invention relates to methods of treating patients with primary immunodeficiency diseases and disorders, using a CXCR4 inhibitor.
Patent WO-2022272197-A1 (WO)
Inventor: SAH DEEPAK
IPC: H04L69/22
Filed: 2022-05-03
Abstract: A transmitter device may be configured to perform to robust header compression optimization to improve channel throughput. In some aspects, the transmitter device may establish a first base context between the transmitter device and a receiver device, wherein a first context identifier is assigned to the first base context, establish a replication context between the devices, wherein the replication context is derivable from the first base context and a second context identifier is assigned to the replication context, and identify a new context. Further, the transmitter device may reassign the first context identifier to the new context, disassociate the second context identifier from the first context identifier, establish a second base context between the devices, wherein a third context identifier is assigned to the second base context, and associate, based on the replication context being derivable from the second base context, the second context identifier to the third context identifier.
Patent WO-2022261640-A1 (WO)
Title: Energy conversion device, associated systems and methods
Inventor: WOODWARD JON
IPC: H02K7/18
Filed: 2022-06-08
Abstract: An energy conversion device may include a shaft including a first portion and a second portion wherein the first portion of the shaft is configured to rotate relative to the second portion of the shaft. A rotor may be coupled to the first portion of the shaft and a stator may be coupled to the second portion of the shaft. A first one-way bearing may be coupled to the first portion of the shaft and configured to transfer rotational input to the first portion of the shaft in a first direction. A second one-way bearing may be coupled to the second portion of the shaft and configured to transfer rotational input to the second portion of the shaft in a second direction opposite the first direction.
Patent WO-2023023649-A1 (WO)
Inventor: DINARELLO CHARLES A
IPC: A61P25/28
Filed: 2022-08-19
Abstract: The present invention is directed to a method for treating Parkinson's disease. The method comprises administering to a subject in need thereof dapansutrile, in an effective amount. Dapansutrile minimizes the clinical features of PD such as locomotor impairments through the modulation of the inflammatory response, reduction in α-synuclein levels, and protection of dopaminergic neurons. A preferred route of administration is oral administration.
Patent WO-2023060110-A1 (WO)
Title: Methods of immune cell analysis
Inventor: MCDONNELL WYATT
IPC: C12N15/10
Filed: 2022-10-05
Abstract: Provided herein are methods for identification chimeric antigen receptors in immune cells as well as method for identification and characterization of immune cells expressing those chimeric antigen receptors.
Patent WO-2023076907-A1 (WO)
Title: Malaria vaccine formulations
Inventor: REIMER JENNY M
IPC: C12N15/62
Filed: 2022-10-25
Abstract: Disclosed herein are immunogenic compositions comprising an antigen of a  Plasmodium  parasite. Methods of administering the aforementioned compositions are also disclosed.
Patent WO-2023086901-A1 (WO)
Title: Borrelia burgdorferi peptidoglycan detection methods
Inventor: JUTRAS BRANDON
IPC: G01N33/569
Filed: 2022-11-10
Abstract: Described herein are assays, techniques, methods, and compositions capable of detecting a Borrelia burgdorferi microorganism, the causative agent of Lyme's disease.
Patent WO-2023102319-A1 (WO)
Title: Chariot robotisé
Inventor: BROOKS RODNEY ALLEN
IPC: B62D51/00
Filed: 2022-11-15
Abstract: La demande concerne des systèmes, des dispositifs, des supports lisibles par ordinateur et des procédés pour la fonction et le fonctionnement de chariots robotisés. Un chariot robotisé peut comprendre un composant de base configuré pour la réception d'une charge utile, une unité de batterie et un appareil de mobilité. Le chariot robotisé peut comprendre un composant de guidon couplé au composant de base. L'unité de guidon peut comprendre une unité de capteur configurée pour transmettre un message de détection de main lorsque l'unité de guidon est saisie par une ou plusieurs mains et pour transmettre un message de direction de force indiquant une direction bidimensionnelle associée à une force directionnelle appliquée par une ou plusieurs mains. Le chariot robotisé peut être configuré pour cartographier la zone autour de celui-ci et pour déplacer de manière autonome le chariot robotisé sur un chemin afin d'exécuter une tâche.
Patent WO-2023133279-A1 (WO)
Inventor: KOSHKAROFF IUSTINIA
IPC: A41D27/28
Filed: 2023-01-06
Abstract: Des aspects de la présente invention concernent un textile composite (112) ayant une couche de substrat (114) (par exemple, tricoté, tissé, non-tissé, etc.) et une couche de film (116) qui est fixée ou liée à la couche de substrat (114). Une pluralité de fentes (120, 1618) s'étend à travers la couche de substrat (114) et la couche de film (116). La couche de film (116) est formée d'un matériau qui se transforme en dimension lorsqu'il est exposé à un stimulus externe tel que l'humidité. Lorsqu'elle est exposée à l'humidité, la couche de film (116) gonfle, ce qui amène des rabats (310, 320) formés par la pluralité de fentes (120, 1618) à s'étendre dans une direction z à l'opposé de la couche de film (116). L'ouverture des rabats (310, 320) crée des passages traversants qui s'étendent à travers l'épaisseur de la structure composite (112).
Patent WO-2023177474-A1 (WO)
Title: Cooling structure of a power supply module
Inventor: MUTO TAKAMI
IPC: H05K7/20
Filed: 2023-01-24
Abstract: A power supply module including a substrate, an electronic component provided on an upper surface of the substrate, a lower board electrically connected with the electronic component through the substrate, and an upper board electrically connected another end of the at least one pillar opposing an end of the at least one pillar that is electrically connected with the at least one lower board, the at least one upper board being electrically connected with the substrate. A pillar extends between the lower board and the upper board. The pillar includes a first end electrically connected with the lower board and a second end electrically connected with the upper board. A magnetic material is provided around a periphery of the pillar.
Patent WO-2023150211-A1 (WO)
Inventor: SZTUL SEBASTIAN
IPC: G06F3/01
Filed: 2023-02-02
Abstract: Eye data is captured with one or more sensors of a head mounted device. The one or more sensors are configured to sense an eyebox region. A differential value is generated by comparing the eye data to previous data. A user notification is generated in response to the differential value reaching an outlier threshold value.
Patent WO-2023154486-A1 (WO)
Title: Traitement contre les poux de tête
Inventor: WRIGHT DEIRDRE
IPC: A61P33/14
Filed: 2023-02-10
Abstract: L'invention concerne une composition destinée à être utilisée dans la lutte contre les poux ou leurs ovules sur un sujet animal, comprenant un copolymère réactif formé de deux monomères ou plus et ayant une partie de conditionnement hydrophobe comprenant un groupe siloxane, un groupe de réticulation réactif comprenant un silanol, une partie hydrophile comprenant un ou plusieurs parmi un groupe éthoxylate et un groupe propoxylate et une partie de liaison de surface comprenant un groupe amine ou ammonium quaternaire, le copolymère formant des réticulations in situ lorsqu'il est séché sur les cheveux. L'invention concerne également un procédé de lutte contre les poux ou leurs ovules chez un sujet animal comprenant l'application sur la tête du sujet animal d'une telle composition.
Patent WO-2023196207-A1 (WO)
Inventor: SADILEK ADAM
IPC: E02F9/20
Filed: 2023-04-01
Abstract: Systems and techniques are described for implementing autonomous control of earth-moving vehicles, including to automatically determine and control movement around a site having potential obstacles. For example, the systems/techniques may determine and implement autonomous operations of excavator vehicle(s) (e.g., obtain/integrate data from sensors of multiple types, and use it to determine and control movement of the excavator vehicle around a site), including in some situations to implement coordinated actions of multiple excavator vehicles and/or of an excavator vehicle with one or more other types of earth-moving vehicles. The described techniques may further include determining current location and positioning of the excavator vehicle on the site, determining a target destination location and/or route of the excavator vehicle, identifying and classifying obstacles (if any) along a desired route or otherwise between current and destination locations, and implementing actions to address any such obstacles.
Patent WO-2023205471-A1 (WO)
Title: Method for fabrication of a multiple range accelerometer
Inventor: BOYSEL ROBERT MARK
IPC: G01P15/08
Filed: 2023-04-21
Abstract: The present disclosure relates to a MEMS inertial sensor device having a plurality of accelerometers formed in a semiconductor chip package wherein the accelerometers are formed in a conductive single crystal silicon SOI wafer bonded to a cap wafer having a hermetic seal. Inertial sensor chip packages can include integrated circuits configured to process inertial sensor data.
Patent WO-2023225334-A1 (WO)
Inventor: SWANSON RONALD
IPC: A61K31/192
Filed: 2023-05-19
Abstract: Provided are methods of treating subjects in need of an anti-fibroblast growth factor receptor 4 (anti-FGFR4) therapy. The methods comprise administering to the subjects a therapeutically effective amount of a peroxisome proliferator-activated receptor (PPAR) alpha agonist in combination with the anti-FGFR4 therapy. The methods can comprise administering to the subject a therapeutically effective amount of PPAR alpha agonist and a bile acid sequestrant. Also provided are compositions comprising an FGFR4 inhibitor, a PPAR alpha agonist, and, optionally, a bile acid sequestrant. The methods attenuate the dysregulation of bile acid biosynthesis caused by FGFR4 inhibition with anti-FGFR4 therapies. The methods reduce the severity and/or incidence of adverse events associated with anti-FGFR4 therapies.
Patent WO-2024015479-A1 (WO)
Title: Financial transaction user interface
Inventor: MESCHER MICHAEL
IPC: G06Q40/06
Filed: 2023-07-12
Abstract: A user device is configured to display a user interface including a price chart and a plurality of user interface elements. Each user interface element is associated with an investment product of a plurality of the investment products. Each user interface element of the plurality of user interface elements includes a bar having a gradient and at least one tick mark positioned on the bar. The user interface enables a user to select a first user interface element of the plurality of user interface elements, position the first user interface element on the price chart, and position the at least one tick mark. A server computer receives an identifier of the first user interface, a first position of the first user interface element on a horizontal axis of the price chart, wherein the horizontal axis represents time, and constructs a corresponding proposed financial transaction.
Patent WO-2024019987-A1 (WO)
Title: Modular force/torque sensor system
Inventor: MCNELLY JOHN
IPC: B25J19/02
Filed: 2023-07-17
Abstract: A modular force/torque sensor system is disclosed. In various embodiments, a sensor interface device includes a first communication interface configured to receive an analog output associated with a sensor located remotely from the sensor acquisition device; a processor configured to use the analog output associated with the sensor to generate a sequence of discrete values derived from the analog output associated with the sensor; and a second communication interface coupled to the processor and configured to send at least a subset of the sequence of discrete values derived from the analog output associated with the sensor to a control module.
Patent WO-2023133450-A1 (WO)
Title: Removable odometer for a non-odometer equipped vehicle
Inventor: DICKINSON KENNETH
IPC: G01C22/02
Filed: 2023-01-05
Abstract: An odometer comprises a housing having a vehicle mounting device attached thereto. In an embodiment, the vehicle mounting device configured to be connectable to and removable from the non-odometer equipped vehicle. The housing further comprises a doppler radar module disposed in the housing. A processor is disposed in the housing and operatively connected to the doppler radar module and memory. In turn, the memory comprises executable instructions that, when executed by the processor, cause the processor to receive, from the doppler radar module, velocity-indicative data relative to a surface traveled by the non-odometer equipped vehicle. Thereafter, the processor operates to determine a distance traveled by the non-odometer equipped vehicle based on the velocity-indicative data.
Patent WO-2023212430-A1 (WO)
Title: Distributed software‑defined network
Inventor: KUNC ROBERT
IPC: H04L41/0806
Filed: 2023-01-30
Abstract: This application relates to a distributed software‑defined network ("DSDN") for dynamically configuring and managing a wireless communication network. A plurality of DSDN nodes are connected to each other via a plurality of communication paths. Each communication path directly connects two DSDN nodes. Each DSDN node can provide DSDN configurations across diverse and disparate networks by normalizing its data plane network traffic through translation and packet encapsulation. Furthermore, the DSDN node can provide an architecture tolerant of network interruptions and network system fluctuations. For example, in the case of any one of the DSDN node's network interruptions from other DSDN nodes, the DSDN can provide network reconfiguration using network configuration rules stored in a control plane of each DSDN node. Therefore, various embodiments can increase network reliability by the multiple nodes within a software‑defined network independently managing its control plane in response to changed network conditions.
Patent WO-2023168435-A1 (WO)
Inventor: DOUGLAS RYAN
IPC: G16H20/30
Filed: 2023-03-03
Abstract: Un appareil et des procédés associés concernent un système de génération de paquet d'induction dynamique (DIPGS). Dans un exemple illustratif, le DIPGS peut comprendre au moins un produit thérapeutique numérique validé (DTx), des profils d'utilisateur et des profils multimédias associés à un contenu multimédia sauvage. Le DIPGS, par exemple, peut comprendre un moteur d'évaluation configuré pour générer ou mettre à jour un profil d'utilisateur sur la base d'un journal d'entrée d'utilisateur et d'observation d'un comportement d'utilisateur. Le DIPGS peut comprendre un moteur de génération de paquet multimédia médical (MMPGE) configuré pour générer un paquet multimédia d'induction dynamique (DUMP). Dans un mode d'induction, le DUMP peut lire régulièrement le contenu multimédia sauvage sélectionné par l'utilisateur. Après la transition du mode d'induction à un mode thérapeutique, la MMPGE génère un contenu de surveillance d'intervention (IMC) comprenant un DTx validé pour fournir un traitement thérapeutique à l'utilisateur. Divers modes de réalisation peuvent avantageusement fournir un guidage médical continu et une surveillance de progression à un utilisateur.
Patent WO-2023205769-A1 (WO)
Title: Réaction de bioconjugaison photochimique chimiosélective et ses procédés d'utilisation
Inventor: CHATTERJEE ABHISHEK
IPC: C07K1/107
Filed: 2023-04-21
Abstract: L'invention concerne une réaction de bioconjugaison de protéine oxydative photocatalytique activée par la lumière visible dirigée vers des acides aminés non canoniques (ncAA) incorporant spécifiquement un site.
Patent WO-2024026216-A1 (WO)
Title: Transmit-beam prediction
Inventor: BAI TIANYANG
IPC: H04B7/08
Filed: 2023-07-14
Abstract: Aspect are direction to techniques for predicting future beams (e.g., transmit beams and/or receive beams) for communications between a network node and a user equipment (UE). In some examples, the UE may output, for transmission to a network node, beam information of a receive beam. The UE may obtain, via a beam pair comprising the receive beam and a transmit beam, signaling from the network node. In some examples, the UE may output, for transmission to the network node, a measurement of the signaling from a perspective of the receive beam.
Patent DK-201670748-A1 (DK)
Title: Spreading device with increased lift
Inventor: ANDREASEN PEDER STAUSHOLM
IPC: G01V1/38
Filed: 2016-09-21
Abstract: A spreading device for trawl fishing, seismic survey operations and other water activities where it is desirable to keep distance between two sides of a towed device, said spreading device having at least one section, which at least one section comprises at least one foil, where the foil has a front surface and a rear surface, said surfaces each being defined by two edges and two side limitations, in use being front and rear edges an upper and lower side limitations and a material thickness between said front and rear surfaces, and where at a predetermined distance from the front edge, on the front surface is provided a bulp at least spanning a majority of the distance between the upper and lower side limitations.
Patent PH-12014501268-A1 (PH)
Title: Methods and compositions for treating viral diseases
Inventor: SHIRIT EINAV
IPC: A61K31/517
Filed: 2014-06-05
Abstract: The invention provides a method for treating viral infections and coinfections through the use of inhibitory agents that prevent a unique viral structural protein motifs from binding to host proteins from the clathrin adaptor proteins family and subsequently preventing viral replication.
Patent PH-12018500110-A1 (PH)
Title: Savoury concentrate comprising inorganic salt, fat and carboxymethyl cellulose
Inventor: BLIJDENSTEIN THEODORUS BEREND JAN
IPC: A23P10/20
Filed: 2018-01-15
Abstract: The in invention relates to a savoury concentrate containing: a) 22-85 wt. pcnt inorganic salt; b) 2-60 wt. pcnt fat; c) 1.8-12 wt. pcnt of carboxymethyl cellulose; d) 0-25 wt. pcnt of glutamate component; e) 0-25 w. pcnt starch component; f) 0-20 wt. pcnt of sugar; g) 0-45 wt. pcnt of vegetable matter; h) 0-10 wt. pcnt water; wherein the components a) to e) together constitute at least 55 wt. pcnt of the savoury concentrate and wherein the components a) to h) together constitute at least 75 wt. pcnt of the savoury concentrate. This savoury concentrate can suitably be used in the preparation of bouillon, broth, soup, sauce or gravy, and not only imparts taste and taste enhancement, but additionally improves texture of the final product.
Patent PH-12019000056-A1 (PH)
Title: A train estimated time of arrival (eta) trailing system
Inventor: CHUA Marissa
IPC: G08G1/123
Filed: 2019-01-31
Abstract: The Estimated Arrival Time Railing System gives you awareness with regards to the exact lime of arrival of each train per station via mobile phones connected to the server and through the Raspberry pi microcontroller with GPS Module installed in each train to develop a Train Estimated Time of Arrival (ETA) Trailing System that can accurately calculate the ETA of the train to the next station. This will allows the passengers to plan their travel ahead of time and the management will easily manage the queuing for each passenger through their websites to avoid passenger's congestion for each station. The inventions data report are visible to the mobile application of the passenger and to the web page as well for detecting errors.
Patent PH-12019500383-A1 (PH)
Title: User identity verification method, apparatus and system
Inventor: HE LE
IPC: H04L29/06
Filed: 2019-02-22
Abstract: Disclosed are a user identity verification method, apparatus and system, relating to the technical field of information. The present invention is primarily used for solving the problems of relatively low accuracy and reliability in an existing user identity verification method. The method comprises: firstly receiving a human face image corresponding to an identity verification object and an eyeprint pair image corresponding to the number of eyeprint acquisition steps, which are sent by a client; then comparing the human face image with a pre-set human face image, and comparing the eyeprint pair image with a pre-set eyeprint template; and if comparison results of the human face image and the eyeprint pair image both satisfy a pre-set condition, sending identity verification success information to the client.
Patent PH-12019500687-A1 (PH)
Title: Point of care assays
Inventor: ANDERSON DAVID ANDREW
IPC: G01N33/576
Filed: 2019-03-29
Abstract: An immunoassay suitable for point of care to assess liver disease or function comprising contacting a blood sample from a subject with a specific binding agent that recognizes an epitope of ALT1, that is not recognized by rodent antibodies when the rodent antibodies are in the presence of human plasma, to form an antigen-binding agent complex and detecting the complex using a second or further binding agent linked to or comprising a detectable reporter; and detecting liver disease or liver function in the subject contingent upon the mass concentration of ALT1 in the sample. Kits or devices comprising lagomorph antibodies or binding agents comprising the antigen binding component thereof suitable for measuring the mass concentration of ALT1 in a blood sample from a subject to determine liver function.