baber/WOPTO huggingface dataset:
Patent JP-2003170045-A (JP)
Title: Exhaust gas treatment catalyst and exhaust gas treatment system using the same
Inventor: NAKAMURA MASAKI
IPC: F01N3/28
Filed: 2001-12-05
Abstract: <P>PROBLEM TO BE SOLVED: To provide an exhaust gas treatment catalyst which can exhibit an NOx adsorption function, an NOx desorption function, and an NOx reduction removal function in good balance at a low cost and an exhaust gas treatment method using the catalyst.  <P>SOLUTION: The exhaust gas treatment catalyst is composed of an upstream side catalyst part and a downstream side catalyst part and the upstream side catalyst part and the downstream side catalyst part contain a catalytic noble metal and an NOx adsorption catalyst and the ratio of the total mole amount of the NOx adsorption catalyst on the basis of an oxide to the total mole amount of the catalytic noble metal in the upstream side catalyst part is smaller than that of the downstream side catalyst part. The exhaust gas treatment system use the exhaust gas treatment catalyst and has 350°C or higher inlet temperature of the upstream side catalyst part.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003170778-A (JP)
Title: Mirror device for vehicle
Inventor: HAYAKAWA HIDEKAZU
IPC: B60R1/02
Filed: 2001-12-06
Abstract: <P>PROBLEM TO BE SOLVED: To reduce looseness between a holding member and an attaching member, and to enhance anti-chattering performance of a mirror.  <P>SOLUTION: In this vehicular door mirror device 10, a mirror holder outer member 30 for holding the mirror 32 for viewing a rear side of a vehicle is assembled to a mirror holder inner member 18 connected to a body side. Elastic plates 42B, 42C or the like provided in the mirror holder outer member 30 have elasticity, and the elastic plates 42B, 42C or the like press elastically an abutting part 20 of the mirror holder inner member 18. A favorable assembling condition between the mirror holder outer member 30 and the mirror holder inner member 18 is kept thereby to reduce the looseness between the mirror holder outer member 30 and the mirror holder inner member 18. Vibration of the mirror holder outer member 30 to the mirror holder inner member 18 is thereby restrained to enhance the chattering performance of the mirror 32.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003176044-A (JP)
Title: Rubber member for feeding and conveying paper
Inventor: YAMASHITA TOMONORI
IPC: B65H3/04
Filed: 2001-12-07
Abstract: <P>PROBLEM TO BE SOLVED: To provide a rubber member for feeding and conveying paper for preventing re-transfer.  <P>SOLUTION: The rubber member for feeding and conveying paper is used so as to contact with a recording surface. An endless belt 10 for feeding and conveying paper has a first core body 12 made of stretchable cloth and a second core body 13 made of a yarn-like core body in a belt body 11 made of butyl- based rubber such as butyl rubber.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003109160-A (JP)
Title: Emergency rescue supporting system, portable terminal with emergency rescue function, wireless terminal for receiving emergency rescue information and emergency rescue supporting method
Inventor: AMI JUNKO
IPC: H04W4/90
Filed: 2001-09-29
Abstract: PROBLEM TO BE SOLVED: To provide an emergency rescue supporting system for enabling an effective emergency rescue or the like. SOLUTION: When the occurrence of an abnormality in the body of a user is detected from the measured value of a biological information sensor 2, a portable terminal 1 originates an emergency call to surrounding portable terminals 3. In each of portable terminals 3, a rescue request message is displayed and the user of the portable terminal 3 recognizes abnormality in the user of the portable terminal 1 and can immediately start dealing or the like. Besides, the portable terminal 1 can display a method of first aid or the like on its display screen or display screen of the portable terminal 3. Further, the portable terminal 1 reports an emergency call via a portable telephone network to a cell center server 7 and the call center server 7 displays a dealing method or the like on the portable terminal 1 and can perform emergency communication or the like as needed.
Patent JP-2002261352-A (JP)
Title: Magnetic spin magnetization device and magnetization rotating device having storage function, and writing method using the device
Inventor: REDON OLIVIER
IPC: H01L43/08
Filed: 2001-12-07
Abstract: PROBLEM TO BE SOLVED: To provide a magnetic spin magnetization device and a magnetization rotating device having a storage function and a writing process using the devices. SOLUTION: The device comprises a magnetization means of electronic spins, which comprises a magnetic body layer (20) magnetized in a direction perpendicular to the magnetization planes of a corresponding fixed layer (12) and a free layer (16). The magnetization direction of the free layer (16) rotates in any plane of the layer or in a plane which is perpendicular to this plane. This device can be applied to an electromagnetic storage device.
Patent JP-2003177257-A (JP)
Title: Long periodic grating optical fiber, long periodic grating component and its manufacturing method
Inventor: TSUDA TOSHIAKI
IPC: G02B6/10
Filed: 2001-12-13
Abstract: <P>PROBLEM TO BE SOLVED: To realize improvement of the component reliability and reduction in the component cost as well as its manufacturing cost while highly maintaining the wavelength dependent characteristics of optical transmission loss in a long periodic grating component.  <P>SOLUTION: This long periodic grating optical fiber 2 is composed of a core layer 10, a first clad layer 12 for clad mode propagation covering the core layer 10, and a second clad layer 13 that covers the first clad layer 12 and that keeps, inside the first clad layer 12, the optical signal of the clad mode propagated through the first clad layer 12.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003180942-A (JP)
Title: Game machine, program, and storage medium
Inventor: TAMURA JUNICHI
IPC: A63F5/04
Filed: 2001-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To eliminate unsatisfaction of a player in application of a privilege accompanying a change of a pay-out ratio.  <P>SOLUTION: A privilege application deciding part 43 is constructed of a previous selection table memory 45, a following selection table memory 46, and a determination part 47. A control part 30a writes the type of a table selected before setting of the pay-out ratio in the previous selection table memory 45 and writes the type of a newly set table in the following selection table memory 46. The determination part 47 compares the type of the table written in the previous selection table memory 45 with that written in the following selection table memory 46 for determining whether a change to a table having the same pay-out ratio is carried out or not. When it is determined that the pay-out ratio is the same as that before the change, the control part 30a sets a prize winning probability of an AT lottery to a high probability. Even if the pay-out ratio is changed, it is determined whether the privilege is given or not without attracting any attention of the player.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003185436-A (JP)
Title: Location measuring apparatus
Inventor: OTOMO FUMIO
IPC: G01C15/00
Filed: 2001-12-18
Abstract: <P>PROBLEM TO BE SOLVED: To provide a location measuring apparatus comprised of a rotating part and a fixed part, provided with a reflecting member at the rotating part, and capable of detecting and correcting a rattle in the rotating part.  <P>SOLUTION: The location measuring apparatus irradiates an object to be measured with measuring light and obtains distances, directions, and locations from reflected light. A light source emits the measuring light, and a light receiving part receives the reflected light. A projecting means direction-freely projects the measuring light and guides the reflected light to the light receiving part. An angle detecting means detects the direction of projection of the projecting means. The light source and the light receiving part are provided in such a way as to be fixed, and the light source emits the measuring light toward the projecting means. The light receiving part receives the reflected light from the object to be measured.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003183562-A (JP)
Title: Pigment composition and pigment dispersion using the same
Inventor: ENDO ATSUSHI
IPC: C09B67/46
Filed: 2001-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a pigment composition and a pigment dispersion using the same which have excellent fluidity and dispersion stability when they are used in an printing ink or a paint, and excellent gloss when they are used in a dry film.  <P>SOLUTION: The pigment composition comprises an organic pigment or a carbon black pigment, a specific basic functional group-containing organic coloring derivative, and a phosphate having a polyether and/or a polyester structure of a number-average molecular weight of 500-30,000. The pigment dispersion comprises the pigment composition of 0.1-50 wt.% a resin of 0.01-50 wt.%, and an organic solvent of 50-99 wt.%.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003184212-A (JP)
Title: Exterior wall
Inventor: AMIMOTO KOJI
IPC: E04F13/24
Filed: 2001-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To improve design properties while enhancing accuracy on the execution of works or workability.  <P>SOLUTION: In an exterior wall 1 in which a ceramic exterior-wall material 9 is installed onto the wall surface 8 of a building through a mounting member 10, the exterior-wall material 9 is formed in an approximately C-shaped cross section, the mounting member 10 has an engaging section 12 engaged with the internal surface of the exterior-wall material 9, and opening P in which accuracy on the manufacture of the exterior-wall material 9 is considered is formed between the internal surface of the exterior-wall material 9 and the engaging section 12 of the mounting member 10 and the opening P is filled with an elastic adhesive 14. A hue having a depth, which cannot be produced by the surface treatment of a metal, and a glossy finishing can be displayed by the ceramic exterior-wall material 9, and design properties are improved while the error of accuracy on the manufacture of the exterior-wall material 9 is absorbed by the opening P and the elastic adhesive 14 and accuracy on the execution of works or workability of the exterior wall 1 is enhanced.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003182373-A (JP)
Title: Belt molding
Inventor: NAGASHIMA HIROYUKI
IPC: B60J10/04
Filed: 2001-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To obtain a belt molding which enables a further light weight.  <P>SOLUTION: All reverse side of a stainless core material is backed with a resin material harder than the elastic contact material which constitutes a glass slide contact lip.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003195236-A (JP)
Title: Device and method for outputting modulated laser light, and original board exposing device
Inventor: KAWAI HIDEAKI
IPC: G02F1/01
Filed: 2001-12-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a modulated laser light output device capable of accurately detecting intensity of laser light outputted from light modulating elements, and controlling the laser light intensity more precisely.  <P>SOLUTION: The modulated laser light output device comprises a light source 2 for outputting the laser light, a light modulator 4 for receiving a modulation signal and an intensity instruction signal 40s in a pulse form and modulating the laser light into pulse form laser light of predetermined intensity, a photodetector 7 for receiving the laser light from the light modulator 4 and outputting an electric signal according to the intensity of the laser light, an A-D converter 32 for converting the electric signal from the photodetector 7 into a digital signal according to a sampling signal 32, a logic circuit 36 as a sampling signal generation means for generating a sampling-capable sampling signal 36s from a peak value of the electric signal 7s based on the electric signal 7s outputted from the photodetector 7, and a CPU 37 as a control means for generating an intensity instruction signal 40s based on the digital signal 32s from the A-D converter 32.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003196608-A (JP)
Title: Shape conversion adapter for electronic card and electronic card module
Inventor: YAMADA HIROYUKI
IPC: B42D15/10
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a shape conversion adapter and an electronic card module usable for a device for another electronic card having different shape from an electronic card and eliminating the separation of the adapter from the electronic card in the device.  <P>SOLUTION: An electronic circuit and the electronic card 200 having an interface of the electronic circuit are inserted, so that this shape conversion adapter 300 converts it into a specific electronic card shape having the external shape larger than the electronic card and the electronic card module 100 is constituted by its installation. An adapter body comprising the adapter 300 is provided with a mount surface 304 mounting the electronic card 200 and engagement parts 301 and 302 retainable the electronic card so as not to move in the insertion/drawing direction into/from the device, when mounting the electronic card. The prescribed device capable of inserting drawing the specific electronic card can be thus used with the electronic card 200 mounted on the adapter 300.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003196372-A (JP)
Title: Method and system for supporting utilization of home equity
Inventor: KUBOTA TAKAYUKI
IPC: G06Q40/06
Filed: 2001-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method and a system for supporting utilization of home equity by which purchase of a house such as large scale change of a living space or rent for which utilization of the home equity is enabled can be supported as living in the house for over many generations and simultaneously in accordance with life styles and life stages and consequently, review of such a house as an asset can be supported.  <P>SOLUTION: A server executes an asset utilization type house purchasing method for supporting the utilization of the home equity, executes a reviewing method of utilization of the asset utilization type house in process of execution or after completion of execution of the asset utilization type house purchasing method, executes an asset utilization purchase simulation method in an execution process of the asset utilization type house purchasing method or the reviewing method of utilization of the asset utilization type house, executes an auction method by utilizing an asset utilization type housing space in an execution process of the reviewing method of utilization of the asset utilization type house and executes a housing loan auction method of the asset utilization type house in an execution process of the asset utilization type house purchasing method or the reviewing method of utilization of the asset utilization type house.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003182298-A (JP)
Title: Decorative bag and decorative strip
Inventor: SAIGA SEIJIRO
IPC: B31B50/22
Filed: 2001-12-13
Abstract: <P>PROBLEM TO BE SOLVED: To provide a decorative bag in which a pattern of a recess shape is attached to an outer surface of the bag and which has excellent design properties and to provide the decorative bag having excellent design properties by laying a colored layer such as a gold foil layer or the like in the pattern of the recess shape.  <P>SOLUTION: The decorative bag comprises the pattern 3 of the recess shape attached to the outer surface of the bag, and the color layer 4 such as the fold foil layer or the like laid in the pattern 3 of the recess shape in such a manner that they are conducted by ultrasonic vibration-working.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-2003500632-A (JP)
Title: ディンプルを形成したバイパスチャンネルを備えた熱交換器
IPC: F01M5/00
Filed: 2000-05-19
Abstract: (57)【要約】
【課題】  低温流れを可能にする所望の低温流体抵抗を発生するが、バイパスチャンネルの流体温度が高くなるに従って高温流体抵抗も発生するように所定の高さ、幅、間隔でディンプル（小さな凹み）を形成したバイパスチャネルを熱交換器に配設することによって従来の問題を解決することである。
【解決手段】  複数の積層プレート対または管（１２）からなる熱交換器である。各（１２）は、所定の内部低温流体抵抗をもつ。これら積層構造にバイパス導管（３８）を配設する。バイパス導管中間に離間係合ディンプル（６８、７８、８０，８２）列を設けて、ディンプル両側に長手方向流路（７２、７４）を形成し、低温流れ条件でこのバイパス導管にバイパス流れを流す。長手方向流路（７２，７４）の低温流体抵抗が積層構造（１２）の低温流体抵抗より低くなるように、これら流路の高さおよび幅を決定する。通常の流れまたは高温流れの条件では、ディンプル（６８、７８、８０，８２）がバイパス導管（３８）に流体を流すことによって流れ抵抗を発生し、速度および方向を変更する。これによって、より多くのオイルが積層構造に流れるため、熱交換性能が高くなる。
Patent JP-2003522439-A (JP)
Title: 音声対残留オーディオ（ｖｒａ）相互作用式補聴装置および補助設備
IPC: G10L21/0324
Filed: 2000-06-15
Abstract: (57)【要約】
オーディオ信号を受信する集積形個別の聴取装置およびデコーダ（３０９）は、オーディオ信号を音声信号と背景信号に分離することによるオーディオ信号復号用のデコーダ（３０９）、音声信号に結合され音声信号を増幅する第１のエンドユーザによる調節可能な増幅器（３１１）、背景信号に結合され背景信号を増幅する第２のエンドユーザによる調節可能な増幅器（３１０）、および第１および第２のエンドユーザによる調節可能な増幅器の出力に結合され合計のオーディオ信号を出力する集計増幅器（３１２）であって該合計のオーディオ信号は個別の聴取装置に結合されるもの、を包含する。
Patent JP-2003503342-A (JP)
Title: ＭＴＰ阻害剤とＨＭＧ−ＣｏＡ還元酵素阻害剤との組み合わせ並びに薬剤におけるその使用
IPC: A61P3/04
Filed: 2000-06-13
Abstract: (57)【要約】
本発明は、心臓血管疾病を制圧するための少なくとも１種の選択されたＭＴＰ阻害剤（成分Ａ）と少なくとも１種のＨＭＧ−ＣｏＡ還元酵素阻害剤（成分Ｂ）よりなる組み合わせの使用に関する。本発明はまたこの組み合わせを含有する薬剤およびそれらの製造にも関する。
Patent JP-2003503617-A (JP)
IPC: E21B6/04
Filed: 2000-06-29
Abstract: A rock drill includes a mounting frame to which a hammering apparatus and a rotating apparatus is arranged. The mounting frame is made maneuverable with respect to a feeding beam by means of slide blocks fastened to it, whereby a separate carriage is not needed between the drill and the feeding beam. Owing to the mounting frame, the hammering apparatus and/or the rotating apparatus can be replaceable modules. The invention further relates to a mounting frame which is arranged to transmit the feed and recoil forces directed to the drill to feeding means. The mounting frame comprises a section parallel to the feeding beam, to which slide blocks are fastened, and a transverse axial support thereto, to which the hammering apparatus and the rotating apparatus are mounted.
Patent JP-2003506023-A (JP)
Title: 高親和性血管内皮増殖因子（ｖｅｇｆ）受容体核酸リガンドおよび阻害剤
IPC: G01N33/50
Filed: 2000-07-26
Abstract: (57)【要約】
ＶＥＧＦ受容体への高親和性核酸リガンドの識別および製造の方法を記載する。本発明中に含まれるのは、ＳＥＬＥＸ法によって識別される、ＶＥＧＦ受容体への特異的ＲＮＡリガンドである。更に含まれるのは、ＶＥＧＦとＶＥＧＦ受容体の相互作用を阻害するＲＮＡリガンドである。
Patent JP-2003507514-A (JP)
IPC: A61K31/365
Filed: 2000-08-10
Abstract: A composition capable of forming a micelle in body fluids or in an aqueous medium and that can be injected into the body undiluted or as a diluted solution in an aqueous medium and method of preparation are disclosed. The composition comprises an amphiphilic block copolymer having a hydrophilic poly(alkyleneglycol) component and hydrophobic biodegradable polymer component, suspended in a poly (alkyleneglycol) medium. Such composition is used in the solubilization and administration of a poorly water-soluble drug.
Patent JP-2003507984-A (JP)
IPC: G04G15/00
Filed: 2000-07-17
Abstract: A banner for a communication device that changes according to the current date is provided. The banner is displayed (13) during standby mode of operation of the communication device. The system for dynamically displaying the banner includes a calendar (21) which has a number of dates. Each of the number of dates has a unique message associated with it. The system also includes software (22a) that compares the current date with the number of dates from the calendar (21). The software (22a) then determines whether the current date matches one of the number of dates from the calendar (21). The display screen (23) of the communication device displays the unique message if the current date matches one of the number of dates from the calendar (21). If the current date does not match one of the number of dates from the calendar (21), the display screen (23) of the communication device displays a default message (14). The calendar (21) may be capable of being edited by a user of the communication device such that additional unique messages may be assigned to any date from the calendar (21). A communication service provider for the communication device may pre-determine the unique message to be displayed for each of the number of dates from the calendar (21).
Patent JP-2003521893-A (JP)
IPC: A01K67/027
Filed: 2000-09-05
Abstract: The present invention provides nucleic acid molecules encoding Fibroblast Growth Factor-like (FGF-like) polypeptides. The invention also provides vectors, host cells, and methods for producing FGF-like polypeptides. Also provided for are methods for the diagnosis and treatment of diseases associated with FGF-like polypeptides
Patent JP-2003509110-A (JP)
IPC: A61C1/00
Filed: 2000-09-11
Abstract: A dental device having at least one pneumatically operable handpiece, the rotational speed of which can be influenced by a control element designed as a foot-operated switch, and a further handpiece, which can be driven by means of an electric drive, and the compressed air present at the pneumatic handpiece influences the control of the electric drive. A graduated filter is mounted on a pneumatically actuated hollow body and the graduated filter has regions thereon which can be sensed by a light barrier generating an electric signal in dependence on the properties of the regions.
Patent JP-2003528818-A (JP)
Title: 皮膚経路を介したワクチン接種による粘膜免疫の誘導
IPC: A61K39/02
Filed: 2000-11-09
Abstract: (57)【要約】
粘膜免疫応答を生成するための方法を記載する。粘膜表面での免疫応答を生成するための方法における使用に適切な組成物もまた記載する。さらに、粘膜表面を介する被検体の体内への病原体の侵入によって生じる疾患の処置または予防のための方法を提供する。１つの局面において、本発明は、脊椎動物被検体の粘膜表面での粘膜免疫応答を生成するための粒子状ワクチン組成物の製造における抗原または抗原をコ−ドする核酸の使用であって、該粘膜免疫応答は、該粒子状ワクチン組成物を、経皮送達技術を用いて、該被検体の皮膚中へまたは該皮膚を横切って送達することによる、使用を提供する。
Patent JP-2003515738-A (JP)
Title: 特に不透明液滴といったような実質的に球形の粒子のサイズを回折によって測定するための装置
IPC: G01B11/08
Filed: 2000-11-28
Abstract: (57)【要約】
本発明は、回折によって、特に不透明液滴とされる、実質的に球形の粒子のサイズを測定するための装置に関するものである。この装置は、光ビームによって照射された粒子（１２）により回折された回折光を受領するとともに、この回折光を複数の同心環状領域へと分離させ、さらに、各環状領域に対応した分の各光を、互いに離間した複数のポイント（２４，２６，２８）へと収束させるための、手段（４６，４９，５０，５１）を備えている。各ポイントに対応して照度が検出され、照度の検出結果に基づいて粒子サイズが決定される。複数の同心領域の角度パターンは、液滴寸法どうしの間の識別を最適化する分布に応じて選択される。
Patent JP-2003515415-A (JP)
Title: ランダムでない巨視的三次元特徴を有する孔なしクリーニングシート
IPC: A47L13/20
Filed: 2000-12-08
Abstract: (57)【要約】
ランダムでないへこみ、および起立領域盛り上げ領域を有する織り地または湿式からみ合わせ孔なしクリーニングシートが開示されている。任意であるが、シートは、スクリム材料か、付着性を改善するための添加物を含むことができる。また、ハンドルと上記孔なしクリーニングシートとを含むクリーニング用具も開示されている。シートの使用方法、孔なしクリーニングシートの製品利点に関する使用説明を付けた製造物品、およびシートを製造するプロセスも開示されている。
Patent JP-2003518845-A (JP)
Title: 高位レイヤの組込みｄｃｔコード化によるファイングラニュラーのスケーラブルなビデオ
IPC: H04N7/30
Filed: 2000-12-05
Abstract: (57)【要約】
本発明は、ファイングラニュラーのスケーラブルなビデオを実現するために組込み方式でビデオデータをコード化する方法を目的とする。この方法は、前記ビデオデータを複数のDCT係数に変換することを含む。更に、前記DCT係数をサブグループに配列し、前記DCT係数を前記サブグループに従って走査する。前記サブグループによってDCT係数を走査することは、より高レベルのスケーラビリティを実現することを可能にする。
Patent JP-2003522376-A (JP)
IPC: H01H33/36
Filed: 2001-02-05
Abstract: The invention relates to an electric circuit breaker that includes at least one mobile contact. The contact is connected to operating means that includes an electric motor (6). Movement converting means (16, 17) are provided for converting rotary movement of the motor (6) to translatory movement for linear movment of the mobile contact. The object is to provide an improved movement conversion means. According to the invention, the movement conversion means includes a first body, such as a screw (17), and a second body, such as a nut (16). The threads of the screw (17) and the nut (16) co-act in engagement with each other. The invention also relates to an electric plant that is equipped with such a circuit breaker, to the use of the breaker for breaking electric current, and to a method of breaking electric current with the aid of the inventive circuit breaker.
Patent JP-2003524001-A (JP)
Title: 新規マロン酸誘導体、それらの製造法、第Ｘａ因子活性の抑制剤としてのそれらの使用、およびそれらを含有する医薬組成物
IPC: A61P9/00
Filed: 2001-02-21
Abstract: (57)【要約】
本発明は血液凝固タンパク質を阻害する新規化合物、さらに詳しくは式(Ｉ)（式中、R(1)、R(2)、R(3)、R(4)、R(5)およびR(6)は特許請求の範囲で定義された意味を有する）のマロン酸誘導体に関する。式(Ｉ)の化合物は血液凝固酵素Ｘａ因子の阻害剤である。本発明はまた、式(Ｉ)の化合物の製造法、Ｘａ因子活性を阻害する方法および血液凝固を阻害する方法、血栓塞栓症のようなＸａ因子活性の阻害により治療または予防することができる疾患の治療および予防における式(Ｉ)の化合物の使用、並びにこのような疾患に適用される薬剤の製造における式(I)の化合物の使用に関する。さらに、本発明は式(Ｉ)の化合物を不活性担体と混合または結合して含有する組成物、特に式(Ｉ)の化合物を薬学的に許容しうる担体物質および補助物質と一緒に含有する医薬組成物に関する。
【化１】