baber/WOPTO huggingface dataset:
Patent PT-1956093-E (PT)
Title: Von willebrand factor (vwf)-cleaving protease
Inventor: SOEJIMA KENJI
IPC: A61K38/48
Filed: 2002-04-25
Abstract: This invention is intended to isolate and identify a vWF-specific cleaving protease.  The vWF-specific cleaving protease cleaves a bond between residues Tyr 842 and Met 843 of vWF and comprises a polypeptide chain having Leu-Leu-Val-Ala-Val as a partial sequence, and more preferably comprises a polypeptide chain having the partial N-terminal amino acid sequence of a mature protein, Ala-Ala-Gly-Gly-He-Leu-His-Leu-Glu-Leu-Leu-Val-Ala-Val, and having a molecular weight of 105 to 160 kDa in SDS-PAGE under reducing or non-reducing conditions. Isolation and identification of this vWF-specific cleaving protease have led to the possibility of replacement therapy for patients having diseases resulting from a deficiency of the protease, such as thrombotic thrombocytopenic purpura.
Patent PT-2194218-E (PT)
Title: A hinge for doors, windows or the like
Inventor: VINADIO AIMONE BALBO DI
IPC: E05D7/00
Filed: 2008-12-05
Abstract: A hinge for doors, windows, or the like, comprising: 
- a first hinge element (12) and a second hinge element (14), which have, respectively, a first cylindrical articulation portion (18) and a second cylindrical articulation portion (22), wherein the first articulation portion (18) has an external diameter smaller than the external diameter of the second articulation portion (22); 
- a hingepin (16), which defines a hinge axis (30); 
- an adjustment device (44), which is associated to one of said articulation portions (18, 22) and can be actuated for displacing said hinge elements (12, 14) with respect to one another in a direction substantially transverse to said hinge axis (30); and 
- a covering sleeve (54), provided externally to the first articulation portion (18) and having an external diameter equal to the external diameter of said second articulation portion (22),  
wherein the covering sleeve (54) is mounted so that it can turn with respect to the first articulation portion (18) about an axis that is eccentric with respect to said hinge axis (30) and can be displaced with respect to the first articulation portion (18) in a direction substantially transverse to the hinge axis (30), the covering sleeve (54) and the first hinge element (12) being provided with toothings (60, 62) kept elastically in a condition of mutual engagement.
Patent PT-2299734-E (PT)
Title: A method and encoder for combining digital data sets, a decoding method and decoder for such combined digital data sets and a record carrier for storing such combined digital data set.
Inventor: BERGHE GUIDO VAN DEN
IPC: H04S3/00
Filed: 2007-10-15
Abstract: Described herein is a method for combining first and second audio signals (21, 31) to form a digital data set (40) in which a subset of samples of each audio signal is modified. A seed sample (A 0 ") from the first audio signal (21) is embedded in the digital data set (40).
Patent PT-821641-E (PT)
Inventor: BARRE PAUL LA
IPC: B29C49/48
Filed: 1996-04-16
Abstract: The invention concerns a device for producing thermoplastic containers, in particular bottles, by the blow-molding or stretch blow-molding of a preheated preform. The device comprises at least one mould consisting of two half-molds (2) each supported by a mould carrier, the two mould carriers being movable relative to each other. Each half-mould (2) comprises a shell holder (9), supported by the respective mould carrier, and a shell (7) which is equipped with a half-impression (8) of the container to be obtained and can be rendered integral in a detachable manner with its shell holder (9) by rapid-fastening means (19-23). The shell (7) and the shell holder (9) are of complementary shapes such that they contact each other at least partially for heat conduction purposes whilst the pipes and connections for circulating and/or heating fluids are provided in the shell holder alone.
Patent PT-847273-E (PT)
Inventor: LESLIE STEWART THOMAS
IPC: A61K47/48
Filed: 1996-09-02
Abstract: PCT No. PCT/GB96/02156 Sec. 371 Date May 8, 1998 Sec. 102(e) Date May 8, 1998 PCT Filed Sep. 2, 1996 PCT Pub. No. WO97/09036 PCT Pub. Date Mar. 13, 1997A process is provided for preparing a granular pharmnaceutical ion exchange resin composition that is readily dispersible in water by granulating an ion exchange resin, having a pharmacologically active ingredient bound thereto, with a particulate sugar or sugar alcohol. The process is characterised by the use of an aqueous solution of a sugar or sugar alcohol as a granulating medium.
Patent PT-816377-E (PT)
Inventor: BAUMBACH GEORGE A
IPC: C07K14/745
Filed: 1997-06-16
Abstract: Peptide ligands which bind to thrombin and prothrombin are disclosed. The sequences of these peptides are Gln-Leu-Trp-Gly-Ser-His, Arg-Gln-Leu-Trp-Gly-Ser-His, His-Gln-Leu-Trp-Gly-Ser-His, and Tyr-Phe-Pro-Gly-Pro-Tyr-Leu. The preferred peptides have the sequence Gln-Leu-Trp-Gly-Ser-His or Tyr-Phe-Pro-Gly-Pro-Tyr-Leu. A method of using these peptides in an affinity chromatography process to purify thrombin is described.
Patent IE-34988-L (IE)
Title: Phenol-formaldehyde resins; insulating materials
IPC: C08J9/10
Filed: 1971-03-08
Abstract: 1283113 Phenol-formaldehyde resins FIBREGLASS Ltd P BODEN P J CROOK M E HALL and S P RILEY 19 April 1971 [13 March 1970] 12311/70 Headings C3C and C3R A phenol -HCHO resin comprises the product of reaction of 1 part wt. of a composition produced by reacting a phenol with concentrated H 2 SO 4 in a ratio of 0À8 to 1À5 moles H 2 SO 4 per mole phenol, and then adding per mole of phenol a quantity of HCHO in the range having a lower limit of 0À3 moles and an upper limit of 0À8 moles when using 0À8 moles H 2 SO 4 and decreasing to 0À5 moles when using 1À5 moles H 2 SO 4 ; with from 0À1-8 parts wt. of a phenol-HCHO resole produced by reacting a phenol and HCHO in the ratio of at least 0À9 moles HCHO per mole phenol in the presence of a basic catalyst. The phenol may be a cresol, 3,5-xylenol or hydroquinone or phenol itself. A solid foam may be produced by reacting the composition with the resole in the presence of a surfactant and a foaming agent. Preferred foaming agents are selected from low boiling point aliphatic hydrocarbons and halogenated derivatives thereof such as CCl 4 , CCl 3 F, CCl 2 F 2 , CF 2 ClCFCl 2 , C 2 Cl 2 F 4 , CHCl 2 F, CH 2 Cl 2 , CH 3 Cl, C 5 H 12 , C 6 H 14 , C 7 H 16 , and C 6 H 5 SO 2 -NHNH 2 . The surfactant is preferably a silicone oil, but may be polyoxyethylene sorbitan monopalmitate or monolaurate. Inorganic fillers such as diatomaceous earth and strengthening materials such as glass beads, glass fibres or glass flake may be incorporated in the foam. Uses.-Fire-retardant insulating material.
[GB1283113A]
Patent IE-31821-L (IE)
Title: Bottle closure cap
IPC: B65D41/18
Filed: 1968-03-14
Abstract: 1,188,315. Caps for bottles. TIVOLI WERKE A.G. 21 Aug., 1967 [15 March, 1967], No. 38384/67. Heading B8T. A cap for a bottle 1 comprises an outer crown 3 of relatively hard plastics, having an integral ring 4 used to retain an inner plug 6 of a softer plastics. The retaining ring 4 is passed through the plug 6 on assembly, and then bent radially outwards for welding over a flange 5 in the plug.
[GB1188315A]
Patent IE-39110-L (IE)
Title: Methyl 3-(2-quinoxalinylmethylene) carbazate n', n-dioxide
IPC: A23K20/195
Filed: 1974-03-29
Abstract: 1462424 Methyl 3-(2-quinoxalinylmethylene)- carbazate-N<SP>1</SP>,N<SP>4</SP>-dioxide PFIZER Inc 15 March 1974 [10 April 1973] 11706/74 Heading C2C The title compound is prepared by reacting a nitrone, acetal, oxime, semicarbazone or thiosemicarbazone derivative of 2-formylquinoxaline-1,4-dioxide with NH 2 NHCO 2 Me or a hydrazone derived therefrom, provided that only said hydrazone may be used for reaction with an acetyl. Reference has been directed by the Comptroller to Specification 1,058,047.
[GB1462424A]
Patent IE-860703-L (IE)
Title: Enzymatic liquid detergent compositions.
IPC: C11D3/42
Filed: 1986-03-19
Abstract: A stable soil release promoting enzymatic primarily nonionic liquid detergent composition comprises a synthetic organic nonionic detergent, an anionic sulf(on)ated synthetic organic detergent, a particular type of soil release promoting copolymer of polyethylene terephthalate (PET) and polyoxyethylene terephthalate (POET), a proportion of enzyme(s) sufficient to enzymatically hydrolyze proteinaceous and/or amylaceous soils on fabrics during washing thereof with an aqueous washing solution of the liquid detergent, a fluorescent brightener, a stabilizing proportion of a stabilizer for the enzyme(s), which also acts as a buffer for the liquid detergent composition to maintain the pH in a certain neutral or slightly acidic range to stabilize the PET - POET copolymer and the fluorescent brightener, and an aqueous medium. The described composition is non-separating and is chemically stable on storage. It substantially retains its soil hydrolyzing, fluorescent brightening and soil release promoting characteristics on storage, so that laundry washed with it is effectively cleaned, brightened, and treated. Also within the invention are processes for manufacturing the product and for utilizing it to wash laundry.
[US4661287A]
Patent IE-39209-L (IE)
Title: Pesticidal products
IPC: A01N25/04
Filed: 1974-04-11
Abstract: 1463008 Two-phase pesticidal composition SOC PROCIDA 11 April 1974 [12 April 1973] 16094/74 Heading A5E A pesticidal composition is made up in two parts. Part A is a powder and comprises some or all of the pesticidally active material and an inert carrier. Part B is a liquid phase comprising water, an oily solvent immiscible wth water one or more emulsifiers and optionally some of the pesticidally active material. The two parts are combined just before use. The active pesticides specified are manganese-1, 2-ethylene-bis-dithiocarbamate; zinc-1, 2-ethylene-bis-dithiocarbamate, 1, 2-bis-(3- methoxycarbonyl-2-thioureido)-benzene, 1, 2- bis-(3-ethoxycarbonyl-2-thioureido)-benzene, 2- (3-methoxycarbonyl-2-thioureido)-aniline; copper sulphate plus lime; copper arsenate plus phenol; cuprous oxide; N-(3, 4-dichlorophenyl)- N'-methoxy-N-methylurea; N-(4-chlorophenyl)- N', N'-dimethylurea; 1-naphthyl-N-methylcarbamate; O, O-dimethyl and S-methyl carbamoyl-methyl-dithiophosphate; Malathion (Registered Trade Mark) and gamma-1, 2, 3, 4, 5, 6- hexachlorocyclohexane. These formulations are useful against vine mildew, wheat rust phytophtora infestans and cercospora.
[GB1463008A]
Patent IE-900847-L (IE)
Title: Fire retardant material
IPC: C09D5/18
Filed: 1990-03-09
Abstract: A fire-retardant coating material includes a fluid intumescent material and refractory fibers of various sizes dispersed or suspended therein for particular applications. The fluid intumescent material includes a foaming agent, a blowing agent gas source, a carbonific or charring agent, a film-forming binder, a solvent and, in some cases, a pigment or filler. The refractory fibers consist of aluminum oxide, silicon dioxide, and one or more other metal oxides.
[US4879320A]
Patent FI-830105-L (FI)
Inventor: SCOTT MALCOLM KEITH
IPC: C07D211/14
Filed: 1983-01-12
Abstract: 4-diphenyl-1-[(oxo and oxo-related alkyl)imino]methylpiperidine derivatives are disclosed which are useful for the inhibition of gastric acid secretion.
Patent FI-830979-L (FI)
Inventor: BANHOLZER ROLF
IPC: C07D451/06
Filed: 1983-03-23
Abstract: The invention herein relates to novel quaternary 6,11-dihydro-dibenzo-[b,e]-thiepine-11-N-alkylnorscopine ethers, the preparation thereof, and their use as spasmolytics or bronchospasmolytics.
Patent FI-844717-L (FI)
Inventor: WERDING WINFRIED JEAN
IPC: A24C5/44
Filed: 1984-11-30
Abstract: Inside a casing comprised of a base plate and two side walls and a cover are mounted a plurality of rollers. The one roller is so supported in slots of the side walls as to be slidable crosswise to the lengthwise axis thereof. The rollers are enclosed by a flexible hose which forms a trough which can receive that tobacco to be converted into a cigatette. A tube-like part on the one side wall can receive a cigarette paper tube inside which the tobacco roll which has been formed between the rollers can be fed by means of the push-rod.
Patent FI-850245-L (FI)
Inventor: BUCHHAVE PREBEN
IPC: G01N15/02
Filed: 1985-01-18
Abstract: PCT No. PCT/DK83/00054 Sec. 371 Date Jan. 16, 1985 Sec. 102(e) Date Jan. 16, 1985 PCT Filed May 18, 1983 PCT Pub. No. WO84/04592 PCT Pub. Date Nov. 22, 1984.In a laser-doppler-apparatus, the size of moving spherical particles in a fluid flow is determined by crossing two spatially separated laser beams (15, 16) to intersect each other under a given angle ( theta ) in a measuring volume passed by a part of the fluid flow. By means of two photoelectric measuring detectors (17, 18) arranged in different spatial positions outside the measuring volume, scattered rays from a moving particle are detected in the form of doppler signals having different phase. The particle size is determined by generating a resulting phase difference signal ( phi M) from the signals from the two measuring detectors (17, 18). By combining the signal from one measuring detector (17) with the signal from a reference detector (19) positioned between the two measuring detectors, a phase reference signal ( phi R) is generated to indicate whether the resulting phase difference signal ( phi M) has been caused by a phase difference between the doppler signals exceeding 2 pi .
Patent IE-791686-L (IE)
Title: Phosphine activated photosensitive compositions
IPC: G03F7/027
Filed: 1979-09-05
Abstract: The compsn. comprises (A) a photopolymerisable, ethylenically unsatd. monofunctional, water-soluble monomer opt. with an ethylenically unsatd. polyfunctional monomer; (B) a water soluble polyvinyl acetate contg. both acetyl and OH gps., having a polymerisation degree of 300-2000 and a saponification degree of 65-99 moles %, (C) a photopolymerisation promoter activatable by actinic light and (D) an activator comprising a phosphine deriv. of formula P (X)(Y)(Z) where X, Y and Z are H, halogen, alkyl, alkoxy, aryl, vinyl or allyl, at most one of X, Y and Z being H and pref. one being aryl. Unlike previous prods. the above does not require prelimination or bump exposure. The exposed prod. is developed by simply washing with water to remove the unexposed zones. Used for prodn. of printing plates.
[IT1162393B]
Patent IE-45594-L (IE)
Title: Cyclopropane derivatives
IPC: C07C69/743
Filed: 1977-09-20
Abstract: Novel polyhalogenated cyclopropane carboxylic acid compounds of the formula <IMAGE> I wherein X1 is selected from the group consisting of hydrogen, fluorine, chlorine and bromine, X2 is selected from the group consisting of fluorine, chlorine and bromine, X3 is selected from the group consisting of chlorine, bromine and iodine and R is selected from the group consisting of hydroxy, halogen, alkoxy of 1 to 7 carbon atoms or R represents OM group wherein M is selected from the group consisting of metal, organic base, acyl of an organic carboxylic acid and an acyl of the said acid in any of the possible isomer forms which are useful as intermediates for the production of pesticidal esters thereof and which also possess antifungal and biocidal activity.
[US4179575A]
Patent IE-782196-L (IE)
Title: Sugar-free hard candy.
IPC: A23L27/30
Filed: 1978-11-06
Abstract: A sugarless candy is provided which has improved flavor and sweetness and contains one or more natural sweeteners, namely, a hydrogenated starch hydrolysate, preferably in combination with a sugar alcohol, such as sorbitol, one or more fruit flavors, together with malic acid which serves as a flavor enhancer.
[US4154867A]
Patent IE-852450-L (IE)
Title: Receiving digital data - adaptive rate recovery
IPC: H04B3/06
Filed: 1985-10-07
Abstract: A digital data receiving arrangement, which adapts itself to channel variations of a transmission system, comprises an adaptive receiver stage (11), having an adaptive equalizer and at least one sampler, and producing, at a certain rate, complex samples yk from the input signal x(t), a decision circuit (14) supplying detected complex samples ak and an adaptive timing recovery circuit (12) determining the optimal sampling instant by minimizing a quadratic function J which represents the difference between yk and ak. The adaptive timing recovery circuit comprises a device (121) for shaping a primary clock signal in accordance with a secondary clock signal, whose period is twice the period of the primary clock and whose consecutive ascending edges are spaced in time by T1 and T2, said secondary clock producing alternately two sampling instants tau and tau + DELTA tau . By minimizing the function J, on the basis of the difference determined for two instants tau k and tau k+ DELTA tau , the control of the timing recovery is defined for the consecutive sampling instants tau k and tau k+1.
[US4669092A]
Patent IE-812975-L (IE)
Title: Use of azolylglycols as plant growth regulants
IPC: A01N43/50
Filed: 1981-12-17
Abstract: alpha -Azolylglycols of the formula   <IMAGE>   where R1 is alkyl, R2 is alkyl or unsubstituted or substituted phenyl or biphenyl, R3 is hydrogen, alkyl, alkenyl, alkynyl or unsubstituted or substituted benzyl and X is CH or N, their plant-tolerated salts and metal complexes, their preparation, and their use as plant growth regulators.
Patent IE-893925-L (IE)
Title: Production and use of porphyrins
IPC: A61P31/04
Filed: 1989-12-07
Abstract: Disclosed is a method and a pharmaceutical composition for killing mammalian tumor cells by subjecting said cells to light in the presence of a light-activatable tetrapyrrole, in which the improvement comprises treating said cells with a compound which inhibits the enzymatic conversion of protoporphyrinogen to protoporphyrin IX by protoporphyrinogen oxidase in said cells thereby causing a buildup of protoporphyrin IX in said cells. Also disclosed is a method for the production of protoporphrin IX which comprises growing eukaryotic microalgae in the presence of a protoporphrinogen oxidase inhibitor.
[CA2004979A1]
Patent IE-940371-L (IE)
Title: Pharmaceutical compositions in the form of solutions¹containing nedocromil
IPC: A61K31/47
Filed: 1987-12-22
Abstract: A method of treatment of a condition selected from the group comprising conjunctivitis, keratitis, 'allergic eyes', adenovirus infections, corneal homograft rejection, anterior uveitis, nasal polyps, vasomotor rhinitis, allergic manifestations of the nasopharynx, reversible obstructive airways disease, Crohn's disease, distal colitis and proctitis, which method comprises administration to a patient suffering from such a condition of a therapeutically effective amount of an aqueous solution containing, as active ingredient, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid or a pharmaceutically acceptable salt thereof. Also described are novel pharmaceutical compositions suitable for use in such methods of treatment.
[US5443833A]
Patent NO-830199-L (NO)
Inventor: TETENBORG KONRAD
IPC: B65D88/16
Filed: 1983-01-21
Abstract: A sack comprises an inner container and a double-ply outer container which latter comprises a tubular or essentially tubular section of which the opposed severed edges are interconnected by a seam. Alternatively, the outer container comprises two such sections having their severed edges interconnected by respective seams.
Patent NO-841741-L (NO)
Inventor: BOYER JACH CLYDE
IPC: E05D11/10
Filed: 1984-05-02
Abstract: A self-locking hinge is disclosed for pivotally attaching a door to a frame member. The hinge includes first and second hinge members which are pivotally joined together by a pin. A socket is formed in the first hinge member which is designed to receive a detent mechanism. The detent mechanism has at least one tooth formed on its lower surface which will engage a complimentary notch formed on the upper surface of the second hinge member upon rotation of the first hinge member relative to the second hinge member. The tooth and notch are so configured as to permit rotation of the first hinge member in one direction but will prevent its rotation in an opposite direction once the tooth has engaged the notch. A spring is positioned located within the socket of the first hinge member so as to bias the detent downward towards the second hinge member. The self-locking hinge is unique in that it permits the detent mechanism to be inserted into the socket at various angular positions so that the tooth is offset from the notch various degrees. This feature permits a door to be opened different amounts, depending upon its application, before the tooth engages the notch and forms a stop.
Patent NO-842990-L (NO)
Inventor: MALINOW M RENE
IPC: C07J71/00
Filed: 1984-07-23
Abstract: Tigogenin cellobioside is a potent inhibitor of cholesterol absorption and therefore useful in treating hypercholesterolemia and arteriosclerosis. Tigogenin cellobioside heptaacetate is useful as an intermediate in preparing tigogenin cellobioside. The two compounds are represented by the formula <CHEM> wherein R is hydrogen or -C(O)CH3, either as a mixture of the  alpha - and  beta -anomers or as the individual  alpha - or  beta -anomer.
Patent NO-854906-L (NO)
Inventor: MUSIL INGRID M
IPC: B32B17/10
Filed: 1985-12-05
Abstract: A polyurethane coating layer, with self-repairing properties, for panes made of glass and/or plastic materials, which are exposed to atmospheric agents. The coating layer according to the invention is formed from a reactive mixture of a trifunctional isocyanate component such as the biurets or isocyanurates of 1,6 hexamethylenediisocyanate, having a content of about 15 to 25% by weight of NCO radicals and a polyalcohol component chosen from the plurifunctional polyester polyalcohols having about a 3 to 12% by weight content of OH radicals.
Patent NO-860913-L (NO)
Inventor: MERYMAN HAROLD T
IPC: A61K35/14
Filed: 1986-03-11
Abstract: The present invention discloses a hypotonic suspension medium and a method for prolonged storage of red blood cells at about 4 DEG  C. The suspension medium comprises about 80-150 mM glucose, 30-80 mM mannitol, 6-90 mM potassium citrate, 1-5 mM adenine and 10-200 mM ammonium chloride or acetate in an aqueous solution having a pH of about 6.8 to 7.2 and an osmolarity of about 180-220 milli-osmolar. The suspension medium and the method of the present invention allow viable storage of red blood cells at about 4 DEG  C. up to 125 days or more.
Patent NO-871481-L (NO)
Inventor: SCHWENDER CHARLES F
IPC: A61K31/455
Filed: 1987-04-08
Abstract: Novel substituted thiacycloalkeno [3,2-b] pyridines are described. These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstrictor activity.
Patent NO-880881-L (NO)
Title: Fremgangsmaate og anordning for automatisk kalibrering av magnetiske kompass.
Inventor: HATCH RONALD R
IPC: G06F/
Filed: 1988-02-29
Abstract: Induksjonskompass av trevlkllngstypen montert 1 et vertsvehlkkel med en Jordet vlkllngsutgang koplet med en analog/digital omformer (162). Hvert vlkllngs-utgangeslgnal D, V, V veles og akkumuleres av eh stakk-krets (166) for å tilveiebringe et tldsfUtrert utgangsslgnal. De filtrerte utgangsslgnalene blir avbildet 1 ekvivalente tovlkllngsutgangsslgnaler når vehlkkelet dreies 1 en 360sirkel for å danne følsomhetsverdler fra vlkllngsavlesnlngene og for å anvende disse verdiene for å tilveiebringe målepara-metere som er Inkorporert 1 en minste kvadraters matrise som ert med hensyn til kallbrerlngs-koeffeslentene for å tilveiebringe kallbrerlngs-parameterne, som representerer forvrengninger på grunn av permanent og Indusert magnetisme til vertsvehlkkelet og på grunn av vlkllngsubalan6e mellom de tre viklingene og fellorlenterlng av de tre viklingene. Kall-brerlngsparametrene tilfares utgangsslgnalene til de tre viklingene for å tilveiebringe et ekvivalent tovlkllngsutgangslgnal som er normalisert for å bestemme den korrigerte kompasskursen.