baber/WOPTO huggingface dataset:
Patent MX-2019008335-A (MX)
Title: Bio-degradable composition and/or probiotic biochemicals and methods of use in leather tanning processes.
Inventor: MATTHEW T WOOD
IPC: C12Q1/02
Filed: 2018-01-12
Abstract: Use of probiotic technology to support tanners to reduce waste and increase the value of by-products reducing the need of synthetic chemicals, improving the quality of effluents and reducing the carbon footprint to the environment. Probiotics or beneficial microorganisms are used to obtain biochemicals through a controlled fermentation of natural ingredients. The result of the process is a consortium of metabolites including viable probiotic microorganisms with properties very similar to traditional leather auxiliaries extensively needed during leather production, eliminating or reducing the need for use of toxic chemicals and compositions.
Patent MX-2019008523-A (MX)
Title: Automatic assembly of glueless pocketed spring units.
Inventor: MARTIN WOLFSON
IPC: B23K37/04
Filed: 2018-01-08
Abstract: Methods and systems for no-glue pocketed spring unit construction. Rows of pocketed springs modules, comprising more than two pocketed springs surrounding a central hole, can be automatically loaded onto an assembler; pocketed spring- surrounded openings can be automatically aligned with welding phalanges; and probe/anvil welding pairs can be inserted into modules in different rows of modules, closed around polymer pocket fabric, and activated to weld rows of modules together without glue; without a user manually loading rows of modules onto the assembler.
Patent MX-2019009101-A (MX)
Title: Sunscreen compositions with natural waxes for improved water resistance.
Inventor: ALEXANDER NARANJO
IPC: A61K8/92
Filed: 2018-02-02
Abstract: A sunscreen composition having improved water resistance comprising (i) a sunscreen active agent; (ii) a water resistant agent comprising a natural wax having a Damping Factor of less than 1.0 in a linear viscoelastic range at body temperature; and (iii) an emulsifier or a surfactant capable of stabilizing an emulsion of components (i) to (iii), wherein said sunscreen composition maintains at least 75%, preferably at least 85%, and most preferably at least 99%, of its static SPF after water immersion for 4 hours.
Patent MX-2019009580-A (MX)
Title: Liquid applicator for delivering vaccines.
Inventor: FREDERIC DAVID
IPC: A61J1/06
Filed: 2018-02-13
Abstract: The invention relates to a liquid applicator, for administering liquids, including vaccines, to animals. In particular, the applicator is useful for delivering liquids to mouths of animals.
Patent MX-2019010649-A (MX)
Title: Inhibitors of beta secretase.
Inventor: DANIEL OEHLRICH
IPC: C07D498/04
Filed: 2018-03-06
Abstract: The present invention relates to tricyclic inhibitors of beta-secretase having the structure shown in Formula (I) and (II) and the tautomers and the stereoisomeric forms thereof, wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
Patent MX-2019013701-A (MX)
Title: Methods of enhancing drug delivery and effectiveness of therapeutic agents.
Inventor: NEIL P DESAI
IPC: A61K9/14
Filed: 2012-09-26
Abstract: The present invention in one aspect provides methods of enhancing uptake of a therapeutic agent in a target tissue as well as methods of treating a disease (such as cancer) or enhancing effectiveness of treatment with a therapeutic agent in an individual by co-administering a composition comprising nanoparticles comprising albumin and a poorly water soluble drug such as a taxane with the therapeutic agent. The present invention in another aspect provides a method of treatment or a method of selecting patients for treatment of a disease (such as cancer) with the combination of a therapeutic agent and a composition comprising nanoparticles comprising albumin and a poorly water soluble drug such as a taxane based on one or more characteristics of the target tissue that correlates or indicates the capability of getting enhanced therapeutic agent uptake as a result of the co-administration of the taxane nanoparticle composition in the target tissue (referred to as "the drug uptake capability"). Also provided are pharmaceutical compositions, article of manufacture, and kits useful for methods described herein.
Patent MX-2019013869-A (MX)
Title: Bistable pull-snap hold open mechanism and method.
Inventor: VISHAAL BOEHM VERMA
IPC: B65D33/00
Filed: 2018-05-25
Abstract: Provided is a fitment bistable pull-snap hold open mechanism including flexible first and second flat, strip like members (12, 14) with one or more pivot members (34) integrated into the second flat, strip like member (14). The flat, strip like members are coupled at their respective ends with two or more bonding points (40). The one or more pivot members include a vertical living hinge and a flexure (50), which allows the mechanism to be biased between an open configuration and a closed configuration. The vertical living hinge does not extend to the top edge or the bottom edge of the second flat, strip like member (14) to improve the integrity of the mechanism. The first and second flat, strip like members (12, 14) are applied proximate the opening of a flexible package on the inside walls and allow the package to be maintained in the open position for removing its contents.
Patent MX-2019014356-A (MX)
Title: Medical puncture instrument.
Inventor: HäRLE ANTON
IPC: A61M25/01
Filed: 2018-06-12
Abstract: The invention relates to a puncture instrument for inserting elongated medical accessories in the body. The puncture instrument comprises a puncturing aid having a metallic shaft (1), its distal end terminating in a cannula tip (2) and its proximal end in a cannula holder (3), a handling means (4; 34) for advancing the puncturing aid, and an axially movable elongated medical accessory (11) inserted in the puncture instrument, the components making said instrument up being already assembled. The distal end (12a or 12b) of the accessory is placed at a predetermined position in the puncture instrument, the handling means is shaped as a handle element having a surface design which can be easily gripped by the fingers and is connected to the cannula hub (5), the accessory inserted in a channel formed by the shaft and the handling means has a greater length than the surrounding channel, the medical accessory (11) can be moved relative to the surrounding shaft (1) and the handling means (4; 34) projects proximally from the handling region.
Patent MX-2019015355-A (MX)
Title: GFCI Test Monitor Circuit.
Inventor: STEPHEN SIMONIN
IPC: H02H9/08
Filed: 2015-09-14
Abstract: ABSTRACT OF THE DISCLOSURE A circuit interrupting device having an auto-monitoring circuit for periodically testing various functions and structures of the device. The auto-monitoring circuit initiates an auto-monitoring routine which, among other things, generates a self-test fault condition and determines whether the detection mechanisms within the device properly detect the self-test fault. Processing an early detection signal determines whether the self-test fault was properly detected without interfering with the normal operation of the detection circuitry and without causing a false trip within the device. Additional functionality of the auto-monitoring circuit permits automatic verification that the device is properly wired, that is, not miswired, and determines whether the device has reached the end of its useful life.
Patent MX-2019015649-A (MX)
Title: Surgical anvil arrangements.
Inventor: HARRIS JASON L
IPC: A61B17/00
Filed: 2018-06-14
Abstract: A surgical stapling anvil is disclosed comprising an anvil body comprising a longitudinal slot configured to receive a firing member therethrough and a tissue-facing surface comprising a plurality of staple-forming pockets defined therein. The anvil further comprises an anvil cap and a plurality of welds welding the anvil cap and the anvil body together. The welds comprise a shallow-welded zone comprising a first weld depth and a deep-welded zone comprising a second weld depth which is different than the first weld depth, wherein the shallow-welded zone and the deep-welded zone are configured to increase overall weld depth of the plurality of welds.
Patent MX-2019015885-A (MX)
Title: Antibody molecules to cd73 and uses thereof.
Inventor: DRANOFF GLENN
IPC: C07K16/28
Filed: 2018-06-21
Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.
Patent MX-2020001268-A (MX)
Title: Metallic and concrete prefabricated piles.
Inventor: SOLANA LOZANO FRANCISCO JAVIER
IPC: E04C3/32
Filed: 2020-01-30
Abstract: The present invention relates to pi prefabricated batches built based on steel or concrete, thus facilitating the process of foundations and reinforcement of the support structures due to their specific structural design and the materials that compose them. Said piles characterize by being buildable, disassemblable, transportable, reusable, and faster to assemble at the foundation site.
Patent MX-2020002128-A (MX)
Title: Multiple geometry and multiple material insulated components.
Inventor: REID AARNE H
IPC: F16L9/14
Filed: 2018-08-24
Abstract: The present disclosure provides insulated components that include corrugated regions, which corrugated regions may reside on inner tubes, outer tubes, or both. The present disclosure also provides insulated components that may achieve straight, curved, or other variable geometries.
Patent MX-2020002925-A (MX)
Title: Substituted nucleosides, nucleotides and analogs thereof.
Inventor: BEIGELMAN LEONID
IPC: C07H19/23
Filed: 2018-09-18
Abstract: Disclosed herein are compounds of the Formula (I) and pharmaceutically acceptable salts thereof: (I) where the variables in Formula (I) are described herein. Methods of synthesizing such compounds and methods of using them to treat diseases and/or conditions such as a <i>Picornaviridae, Flaviviridae, Filoviridae, Pneumoviridae</i> and/or <i>Coronaviridae </i>viral infections are also disclosed.
Patent MX-2020003126-A (MX)
Title: Cyclic iminopyrimidine derivatives as kinase inhibitors.
Inventor: CHEN CHEN
IPC: A61K31/517
Filed: 2018-09-20
Abstract: Provided are cyclic iminopyridimdine compounds and their bicyclic derivatives, pharmaceutical compositions comprising such compounds, and methods of using such compounds or compositions, such as methods of treating a proliferation disorder, such as a cancer or a tumor, or in some embodiments disease or disorders related to the dysregulation of kinase such as, but not limited to B-Raf V600E kinase.
Patent MX-2020004800-A (MX)
Inventor: BROWN LESLEE
IPC: G01M13/023
Filed: 2018-11-07
Abstract: Un sistema de monitoreo de impulsor por correa que comprende un impulsor, un impulsado, el impulsor y el impulsado conectados por medio de un miembro sin fin, un primer miembro magnético que tiene un campo magnético unido al impulsor, un segundo miembro magnético que tiene un campo magnético unido al impulsado, un primer sensor dispuesto para detectar un campo magnético causado por pasaje del primer miembro magnético, un segundo sensor dispuesto para detectar un campo magnético cambiante causado por el pasaje del segundo miembro magnético, un primer transmisor configurado para transmitir de manera inalámbrica a un receptor una primera señal de datos del primer sensor y un segundo transmisor configurado para transmitir de manera inalámbrica al receptor una segunda señal de datos del segundo sensor, y el receptor configurado para manipular la señal de datos pro la cual un parámetro de sistema se calcula y proporciona a un usuario.
Patent MX-2020004991-A (MX)
Title: Cancer therapy by degrading dual mek signaling.
Inventor: HERGENROTHER PAUL J
IPC: A61K31/4184
Filed: 2018-11-16
Abstract: The discovery of mutant or fusion kinases that drive oncogenesis, and the subsequent approval of specific inhibitors for these enzymes, has been instrumental in the management of some cancers. However, acquired resistance remains a significant problem in the clinic, limiting the long-term effectiveness of most of these drugs. Herein is demonstrated a strategy to overcome this resistance through drug-induced MEK cleavage (via direct procaspase-3 activation) combined with targeted kinase inhibition. This combination effect is shown to be general across diverse tumor histologies (melanoma, lung cancer, and leukemia) and driver mutations (mutant BRAF or EGFR, fusion kinases EML4-ALK and BCR-ABL). Caspase-3-mediated degradation of MEK kinases results in sustained pathway inhibition and substantially delayed or eliminated resistance in cancer cells in a manner superior to combinations with MEK inhibitors. These data suggest the generality of drug-mediated MEK kinase cleavage as a therapeutic strategy to prevent resistance to targeted anticancer therapies.
Patent MX-2020011442-A (MX)
Title: Galvanized steel sheet and production method therefor.
Inventor: UCHIDA SATOSHI
IPC: C21D9/46
Filed: 2019-04-26
Abstract: This galvanized steel sheet comprises: a steel sheet having a prescribed chemical composition; and a galvanized layer. The steel sheet has a steel composition in a range of 1/8-3/8 thickness, centered on Â¼ thickness from the surface, and contains: 0-10 vol% of ferrite, 0-30 vol% of bainite, at least 50 vol% of tempered martensite, 0-10 vol% fresh martensite, more than 10 vol% and no more than 30 vol% residual austenite, and 0-5 vol% pearlite. The galvanized steel sheet: has, per steel plate mass, no more than 0.40 ppm hydrogen released when the steel plate is heated from room temperature to 200Â°C after the galvanized layer is removed; has a tensile strength of at least 1,470 MPa, and does not crack in a U-bending test during which a stress equivalent to 1,000 MPa is applied for 24 hours.
Patent MX-2020011995-A (MX)
Title: Segmented gel composites and rigid panels manufactured therefrom.
Inventor: EVANS OWEN R
IPC: C04B41/45
Filed: 2015-01-07
Abstract: The present invention describes various methods for manufacturing gel composite sheets using segmented fiber or open-cell foam reinforcements and gel precursors. Additionally, rigid panels manufactured from the resulting gel composites are also described. The gel composites are relatively flexible enough to be wound and when unwound, can be stretched flat and made into rigid panels using adhesives.
Patent MX-2020014188-A (MX)
Title: Formulation and method for preparing a functional cookie-type food with high phenolic content, antioxidant activity, and sensory improvements with grape peel.
Inventor: AGUILAR GONZÁLEZ CRISTÓBAL NOÉ
IPC: A21D13/80
Filed: 2020-12-18
Abstract: The present invention relates to a formulation and preparation method of a biscuit-type functional food with high phenolic content, antioxidant activity, and sensory improvements with grape skin. It relates to a residue derived from the wine industry, whose formulation includes wheat flour, grape skin flour waste from the wine industry with a particle size of <150Ám and in an amount of 10% for wheat flour, sugar, vegetable shortening, egg, and vanilla. Also, it refers to a process for preparing said functional biscuit, consisting of mixing the ingredients to obtain a dough, making forms with a thickness of one centimeter and a diameter of four with cookie cutters, placing them on a buttered plate, and cooking in an oven at 120 °C for 20 minutes.
Patent MX-2021001066-A (MX)
Title: Electrically activated valve actuator for an internal combustion engine.
Inventor: HEDMAN MATS
IPC: H01F7/16
Filed: 2019-07-29
Abstract: The present invention concerns a method and a device for electrically controlling a valve actuator in a two-stroke or four-stroke combustion engine where the actuator comprises a solenoid (A), a plunger (5) and a spring (6), wherein the engine has at least one cylinder (1) with at least one freely controllable engine valve with a valve disc (10) with corresponding valve stem (11) and a valve spring (4), where a distance (7) is provided between the lower end of the plunger and the upper end of the valve stem and where air is supplied, or exhaust gases are evacuated from, a combustion chamber (3) past a lower part of the valve stem with the valve disc via at least one channel (2) in the cylinder, wherein the valve actuator is activatable to open the engine valve. The invention is characterized in that the opening of the engine valve is initiated after activation of the solenoid, wherein the following acceleration of the plunger brings its lower end to strike the upper end of the valve stem for initial opening of the valve.
Patent MX-2021003154-A (MX)
Title: Compositions and methods for treating cellulite.
Inventor: MCLANE MICHAEL
IPC: A61K8/66
Filed: 2019-09-04
Abstract: The present disclosure relates to a method of treating cellulite on a thigh or buttock in a human subject by administering an effective amount of collagenase, and then assessing the reduction in the severity of cellulite by one or more scales.
Patent MX-2021007405-A (MX)
Title: Gas expansion and fluid compression station.
Inventor: ONFROY YANNICK
IPC: F17D1/04
Filed: 2019-12-20
Abstract: Disclosed is a station (100) for expanding a flow of gas having, at the inlet, a temperature Ta and a pressure Pa, that comprises: - an expansion valve (105) for recovering mechanical expansion energy configured to reduce the pressure of the gas flow to a pressure Pb and to a temperature Tb such that Pb < Pa and Tb < Ta, - a compressor (110) for compressing a flow of fluid having, at the inlet, a temperature Tc and a pressure Pc, the expansion valve and the compressor being mechanically combined such that the movement of the expansion valve when the gas expands causes the compressor to be actuated such that the fluid is compressed to a pressure Pd and a temperature Td such that Pd > Pc and Td > Tc and - a heat exchanger (115) for exchanging heat between the gas flow at the outlet or inlet of the expansion valve and the fluid flow at the outlet or inlet of the compressor in order to heat the gas and cool the fluid.
Patent MX-2021008432-A (MX)
Title: Pharmaceutical compositions and uses directed to lysosomal storage disorders.
Inventor: STRUPP MICHAEL
IPC: A61P25/00
Filed: 2019-02-07
Abstract: The present disclosure provides for treating lysosomal storage disorders (LSDs) comprising administering acetyl-leucine or a pharmaceutically acceptable salt thereof.
Patent MX-2021011204-A (MX)
Title: An antiperspirant composition comprising reactive salts.
Inventor: LI XIAOKE
IPC: A61K8/28
Filed: 2020-03-12
Abstract: The present invention is in the field of antiperspirant compositions, in particular, compositions comprising antiperspirant actives. Disclosed is an aqueous antiperspirant composition having pH 2 to 5, comprising: (i) a water-soluble phosphate salt; (ii) a water-soluble non-phosphate salt; and, (iii) a retarding agent; wherein said water-soluble phosphate salt is selected from monosodium phosphate, disodium phosphate, trisodium phosphate, monopotassium phosphate, dipotassium phosphate, tripotassium phosphate, monoammonium phosphate, diammonium phosphate, triammonium phosphate, lithium dihydrogen phosphate, dilithium hydrogen phosphate and lithium phosphate; wherein said water-soluble non-phosphate salt is selected from calcium chloride, calcium gluconate, calcium nitrate, calcium bromide, calcium formate, calcium lactate, calcium propanoate, calcium acetate, calcium dobesilate, magnesium chloride, magnesium nitrate, magnesium sulphate, magnesium citrate, magnesium gluconate, magnesium acetate, magnesium lactate, magnesium malate, ferric chloride, ferric nitrate, ferric sulphate, zinc chloride, zinc nitrate, zinc citrate, zinc sulphate, zinc gluconate, copper chloride, copper sulphate, copper nitrate, copper(II) acetate, copper(II) gluconate, iron(III) citrate, zirconium nitrate, zirconium tetrachloride, zirconium oxychloride, strontium chloride, strontium nitrate, barium chloride, barium nitrate, lanthanum chloride, lanthanum acetate, Tin(II) chloride, Tin (IV) chloride, and silver nitrate; wherein said retarding agent is a compound which comprises at least one functional group selected from -COOH, -COO<sup>-</sup>, -SO<sub>3</sub>H or -SO<sub>3</sub> <sup>-</sup>; wherein said composition is not a dentifrice; wherein said water-soluble phosphate salt, water-soluble non-phosphate salt and retarding agent are present in one phase; wherein the solubility of said salt in water is assessed at 25Â°C and atmospheric pressure.
Patent MX-2021012124-A (MX)
Title: Quinolyl-containing compound and pharmaceutical composition, and use thereof.
Inventor: WU WEI
IPC: A61P1/16
Filed: 2020-03-30
Abstract: Provided is a quinolyl-containing compound as shown in general formula (I) or (II) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotopic label, or an isomer thereof, and further provided are a pharmaceutical composition comprising the compound and use of the compound and the pharmaceutical composition. The provided compound has a dual molecule function, can serve as multi-target inhibitors of novel tyrosine kinase/histone deacetylase, can simultaneously achieve the effect of two inhibitors, has excellent biological activity and pharmacokinetic properties, and has the application potential particularly in the field of treatment of tumors.
Patent MX-2021014542-A (MX)
Title: Active and passive humidification device for mounting in a patient ventilation circuit.
Inventor: CAREY PAURIC
IPC: A61M16/00
Filed: 2020-05-29
Abstract: An active and passive humidification device (1) for mounting in a patient ventilation circuit comprises a housing (2) having a ventilator chamber (3) and an associated patient chamber (4) communicating with the ventilator chamber (3) through a gas permeable filter (5) mounted between the ventilator chamber (3) and the patient chamber (4), This filter (5) forms a passive humidifier which is operable in use to capture and reflect heat and moisture received from a patient back to the patient. The ventilator chamber (3) has a ventilator connector port (9) for connection to a ventilator. The patient chamber (4) has a patient connector port (10) for connection to a patient breathing tube (13). A humidity generating device (15) is integrated in the housing (2) and is operable to control the humidity of air delivered from the patient chamber (4) through the patient connector port (10) to a patient and provides for active humidification of the breathing air. The humidity generating device (15), an air flow sensor (38), a temperature sensor (39) and a ceramic heater plate (40) of the device (1) are all connected to an associated controller which regulates operation of the humidity generating device (15) and heater plate (40) to maintain air at a desired temperature and humidity for delivery from the patient chamber (4) to a patient.
Patent MX-2021015289-A (MX)
Title: Methylthioninium as enhancers of the cognitive function.
Inventor: HARRINGTON CHARLES ROBERT
IPC: A61K31/5415
Filed: 2020-06-29
Abstract: The present invention relates generally to nootropic compositions comprising Leuco-methylthioninium acid salts and their uses for cognitive enhancement in normal (non-demented) individuals.