baber/WOPTO huggingface dataset:
Patent DE-69018361-T2 (DE)
Inventor: BLASI FRANCESCO
IPC: A61P7/02
Filed: 1990-04-11
Granted: 1995-08-31
Abstract: Phosphorylated plasminogen activator, such as phosphorylated pro-urokinase (pro-u-PA), which is substantially free from unphosphorylated plasminogen activator, may be obtained by phosphorylating unphosphorylated plasminogen activator with a phosphorylating enzyme or by separating phosphorylated plasminogen activator from a mixture of phosphorylated plasminogen activator and unphosphorylated plasminogen activator. Phosphorylated pro-u-PA, which is substantially free from unphosphorylated pro-u-PA, is converted by plasmin into phosphorylated u-PA. The phosphorylated plasminogen activators such as phosphorylated pro-u-PA, u-PA and t-PA are useful as thrombolytic agents.
Patent DE-69020723-T2 (DE)
Inventor: FURUHATA HIROSHI
IPC: A61B8/14
Filed: 1990-04-20
Granted: 1996-01-18
Abstract: An ultrasonic diagnostic device is disclosed in which ultrasonic pulses are transmitted for a subject body in changing the position and direction of a probe (11), and a plurality of two-dimensional tomographic image signals obtained by detecting the reflected pulses are synthesized to form a three-dimensional image. A signal for identifying the position in three-dimensional coordinates based on the position and direction of the probe (11) at the time of detection is given to individual picture element signals composing the detected two-dimensional tomographic image. A plurality of two-dimensional tomographic image signals having identified positions in three-dimensional coordinates are obtained by the similar processes to described in the above in changing the position and direction of the probe (11), and a plurality of the picture element signals having the same coordinates are addition-averaged and are stored in the memory area (48) corresponding to the coordinates in the three-dimensional memory. With the arrangement as described in the above, the three-dimensional image can be formed which is not influenced by hardness in the tissue etc. <IMAGE>
Patent DE-69020739-T2 (DE)
Inventor: MCLAIN STEPHAN
IPC: C08J5/18
Filed: 1990-09-05
Granted: 1995-11-23
Abstract: Process for yttrium and rare earth compound catalyzed polymerization of lactones and the living polymer compositions of such polymerizations, novel polyester products of such polymerizations and novel yttrium and rare earth metal compounds useful as catalysts in the polymerization of biodegradable polymers for medical uses and flexible films for packaging.
Patent DE-69025476-T2 (DE)
Inventor: HEALEY PETER
IPC: H04B10/00
Filed: 1990-07-30
Granted: 1996-07-25
Abstract: A monitor unit (1) for detecting physical interference of a communications fibre (4) in a transmission system (2) comprises a monitor circuit (9) coupled to the communications fibre (4). A portion of a signal being transmitted along the communications fibre (4) is coupled out of the fibre (4) and into the monitor unit (1). A filter (8) allows only one of two orthogonal polarisation field components to pass through it to the monitor circuit (9). By detecting fluctuations in the polarisation state of the filtered optical signal, the monitor circuit (9) allows the detection of external influences to be determined.
Patent DE-69026451-T2 (DE)
Inventor: BEALKOWSKI RICHARD
IPC: G06F9/06
Filed: 1990-07-04
Granted: 1996-10-10
Abstract: An apparatus and method for loading BIOS stored on a direct access storage device (62,66) into a personal computer system (10). The personal computer system (10) comprises a system processor (26), a system planar (24), a random access main memory, a read only memory (36), and at least one direct access storage device (62,66). The read only memory (36) includes a first portion of BIOS and data representing the type of system processor (26) and system planar (24) I/O configuration. The first portion of BIOS initializes the system (10) and the direct access storage device (62,66) to read in a master boot record into the system (10) from the direct access storage device (62,66). The master boot record includes a data segment (122-138) and an executable code segment (120). The data segment (122-138) includes data representing system hardware and a system (10) configuration which is supported by the master boot record. The first BIOS portion confirms the master boot record is compatible with the system hardware by verifying that the data from the data segment (122-138) of the master boot record agrees with the system processor (26), system planar (24), and planar I/O configuration. If the master boot record is compatible with the system hardware, the first BIOS portion vectors the system processor (26) to execute the executable code segment (120) of the master boot record. The executable code segment (120) confirms that the system configuration has not changed and loads in the remaining BIOS portion from the direct access storage device (62,66) into random access memory (32). The executable code segment (120) then verifies the authenticity of the remaining BIOS portion and vectors the system processor (26) to begin executing the BIOS now in random access memory (32). BIOS executing in random access memory (32) then boots up the operating system to begin operation of the personal computer system (10).
Patent DE-69103680-T2 (DE)
Inventor: ELIZABE PIERRE
IPC: A62C13/00
Filed: 1991-06-04
Granted: 1995-03-16
Abstract: The cartridge (5) is disposed floating freely in water (1a) which fills a water extinguisher (1, 2), put under pressure for use by perforating the diaphragm of a capsule (13) of liquid carbon dioxide, to be forced through the plunger tube (6) and the nozzle (6a). The cartridge (5) comprises a tubular body (10) made from polyethylene with an opening at the lower end (12) which is closed off by a cap (13) formed from an aluminium foil with a layer of polyethylene on the inner side, thermally welded to the edge of the body. An additive (14) of the floating-film-forming agent type is contained at the lower portion of the body (10) with a free space (15) above it which ensures a positive buoyancy and vertical immersion stability. During the rise in pressure, towards 0.4 MPa, the cap (13) tears and the inrush of water into the body disperses the additive. <IMAGE>
Patent DE-69108879-T2 (DE)
Inventor: NUNS JACQUES
IPC: H05B6/10
Filed: 1991-11-20
Granted: 1995-09-14
Abstract: Molecular distillation apparatus of the type including a conical metal rotor (12) driven in rotation and fed in its centre with a liquid to be distilled, a vacuum bell (10) defining an enclosure sheltering the cone and means for heating the rotor by induction which are situated below and near the rotor. According to the invention the means for heating include at least two concentric inductors (100a, 100b, 100c) providing homologous regions of the rotor with different heating power densities. The invention also relates to a process for the manufacture of a combination of rotor and of inductors for such an apparatus. <IMAGE>
Patent DE-69109913-T2 (DE)
Inventor: KIM YONG ZU
IPC: A61P31/04
Filed: 1991-03-21
Granted: 1995-12-07
Abstract: The present invention provides certain novel cephalosporin derivatives represented by following formula(I), which are especially useful as intermediates for the preparation of cephalosporin compounds possessed with potent and broad antibacterial activities. <CHEM>  wherein: R<1> is a C1-4alkyl, C3-4 alkenyl, C3-4 cycloalkyl, amino optionally substititued with a C1-4 alkyl radical, or phenyl group optionally subsitututed on its 2-, 4-and/or 6-position with a halogen, C1-4 alkyl, C1-3 alkoxy or hydroxy radical;  R<2> is hydrogen or a C1-4 alkyl group; and  n is either 0 or 1. The invention also relates to processes for preparing these intermediates and their pharmacologically active cephalosporin antibiotics.
Patent DE-69114810-T2 (DE)
Inventor: CHABALA LEONARD V
IPC: F16J15/16
Filed: 1991-09-24
Granted: 1996-05-02
Abstract: A sealing arrangement (e.g. 10 or 50) is provided with overpressure relief. In the preferred embodiment, the sealing arrangement (10 or 50) includes a sealing member (22 or 52) that is positioned between two housing portions (12,14) or the like and that is acted upon by the pressure (P) within the housing, A force-responsive retaining arrangement (26 or 60) maintains the sealing member (22 or 52) in a predetermined location. Upon the occurrence of overpressures exceeding a predetermined value (P1), the sealing member (22 or 52) exerts sufficient force on the force-responsive retaining arrangement (26 or 60) so as to cause appropriate displacement of the sealing member (22 or 52) to permit the venting of the housing. <IMAGE>
Patent DE-69120144-T2 (DE)
Inventor: ELLIOT JOHN LANE
IPC: D06C23/00
Filed: 1991-03-05
Granted: 1996-10-24
Abstract: A method and apparatus for treatment of relatively moving substrate materials by preheating the substrate before precise selective application of discrete, high temperature pressurized streams of fluid against the surface of the materials to impart a visual and tactile change thereto. The apparatus includes an elongate manifold for receiving heated pressurized fluid, such as air, disposed across the width of the relatively moving material and having a single slit the full width of the substrate for directing the fluid into the surface of the material. Pressurized cool fluid, such as air, is directed across selected portions of the manifold discharge slit to deflect pressurized heated air away from the substrate. The manifold is provided with cool air outlets which direct the heated air to a position upstream of the path of movement of the substrate for preheating purposes. The apparatus is further arranged and configured to enhance the visibility of faults in the substrate. <IMAGE>
Patent DE-69132863-T2 (DE)
Inventor: WUCHERPFENNING W
IPC: C12Q1/68
Filed: 1991-03-29
Granted: 2002-06-20
Abstract: This invention is directed to therapeutic agents comprising peptides in turn comprising a portion of the T-cell manifested in multiple sclerosis. Embodiments of the invention include peptides, vaccines, receptors and entire (attenuated) T-cells. This invention is also directed to methods using the foregoing agents to suppress immune response against myelin basic protein, and/or to suppress T-cells that recognize an immunodominant epitope of human myelin basic protein. Additionally, this invention is directed to diagnostic methods and kits for diagnosing multiple sclerosis.
Patent DE-69132988-T2 (DE)
Inventor: KOBYLARZ E
IPC: H04B7/26
Filed: 1991-01-22
Granted: 2002-10-17
Abstract: A process to reduce the howl condition in a radiotelephone when the microphone picks up audio from the speaker. The condition is detected by first lowering the speaker volume (103) and measuring the microphone volume for a corresponding decrease (104). The speaker volume is then increased (105) and the microphone volume is again measured for a corresponding increase (106). If the microphone volume follows the speaker volume, a howl condition has been detected. To eliminate the condition without the volume fluctuations being noticed by the parties conversing, the microphone and speaker volume is reduced in small increments (114) until the condition is eliminated.
Patent DE-69206327-T2 (DE)
Inventor: SPONHOLTZ PER
IPC: A23G9/32
Filed: 1992-06-16
Granted: 1996-04-25
Abstract: The disclosure relates to a method of producing and pre-distribution preparing unfrozen, expanded ice cream mix with superior storage and shelf-life properties. Starting ingredients necessary for producing the ice cream mix are mixed together, whereafter the mix is heat-treated or otherwise treated so as to exterminate micro-organisms, in particular pathogenic bacteria, present in the mix. The thus treated mix is expanded and subsequently packed in packages ready for distribution. Ice cream mix produced according to this method has extended shelf-life and can be stored in the unfrozen state for long periods of time with retained pristine freshness qualities, without any requirement of cold storage at extremely low storage temperatures.
Patent DE-69222838-T2 (DE)
Inventor: KATO MOTOKI
IPC: H04N19/90
Filed: 1992-07-16
Granted: 1998-04-02
Abstract: A coding and decoding device for a time-varying picture, by which a high picture quality is obtained from a smaller amount of information than a system using only DCT coding. The efficiency of coding can be increased and the block distortion of a composite image is reduced. An image is divided into several blocks, and each block is coded. At this time discrete cosine transformation coding (DCT) and intrablock predictive composing (NTC) are switched over to each other adequately according to the property of the image pattern. When the intrablock predictive composing is executed, the predictive value and quantization width of a block are transmitted. <IMAGE>
Patent DE-69223602-T2 (DE)
Inventor: DENISSEN ADRIANUS JOHANNES M
IPC: B30B15/02
Filed: 1992-12-23
Granted: 1998-06-10
Abstract: A device for processing digital data comprises a memory, error detection means and control means which selects addresses for the writing of the data in the memory on the basis of errors detected in the data, and which selects further addresses for the reading of data from the memory. Thus, only reliable data is read so that a high picture quality is achieved in a digital video system, despite the presence of errors in the data.
Patent DE-69226703-T2 (DE)
Inventor: WHITTAKER MARK
IPC: C07F7/18
Filed: 1992-07-24
Granted: 1999-02-18
Abstract: PCT No. PCT/GB92/01370 Sec. 371 Date Feb. 28, 1994 Sec. 102(e) Date Feb. 28, 1994 PCT Filed Jul. 24, 1992 PCT Pub. No. WO93/02080 PCT Pub. Date Feb. 4, 1993.Compounds of formula I:     <IMAGE>  I  wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and B are variables. These compounds are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.
Patent DE-69229730-T2 (DE)
Inventor: ROLCHIGO PHILIP
IPC: B01D33/21
Filed: 1992-05-28
Granted: 1999-12-02
Abstract: A rotary disc filtration device having a fluid filtration gap between a filtration surface and a disc is disclosed. The disc and/or filter has one or more spiral grooves in fluid communication with fluid in the gap. The disc and/or filter is rotated and one or both may be axially oscillated and/or vibrated to create the shear at the filter surface that increases permeate flux through the filter. Several discs and filters may be interleaved to increase filtration device capacity and make more efficient use of equipment space. In such a device, the discs can be mounted on a common shaft for rotation in unison and can have spiral grooves on both major faces of each disc. The filters are held stationary in that device and are fluidly connected to facilitate collection of the permeate.
Patent DE-69232479-T2 (DE)
Inventor: TER HUURNE AGNES
IPC: A61K39/002
Filed: 1992-12-18
Granted: 2002-10-31
Abstract: According to the present invention a vaccine can be prepared containing a mutant Serpulina hyodysenteriae which is defective in its production of biologically active hemolysin. The mutation by which Serpulina hyodysenteriae is made defective in its production of hemolytically active hemolysin is established by means of genetical engineering techniques. Such mutations comprise e.g. deletion of part or the entire gene coding for hemolysin and/or nucleotide sequences controling the production of hemolysin, or insertion of an extra nucleotide or polynucleotide into the gene encoding hemolysin and/or the nucleotide sequences controling the production of hemolysin, or a combination of said deletion and insertion. These vaccines are useful in the prevention of Serpulina infections in susceptible animals such as swine.
Patent DE-69309071-T2 (DE)
Inventor: KNEISEL ANDREW
IPC: C03C27/04
Filed: 1993-08-11
Granted: 1997-08-14
Abstract: This invention relates to a process for bonding a vehicle window to a vehicle flange comprising the sequential steps of: a) applying a liquid masking composition to a vehicle flange, b) painting the vehicle, and drying or curing the liquid masking composition sufficiently to form a strippable mask; c) removing the mask from the flange; and d) adhesively bonding the vehicle window to the vehicle flange. Such a masking process advantageously eliminates the need for the use of solvent-based primers normally used to prime a painted vehicle flange, and provides a mask which is more easily applied and removed from the flange than masking means which initially comprise a solid substance.
Patent DE-69309709-T2 (DE)
Inventor: DOS SANTOS EMMANUEL
IPC: B01J23/46
Filed: 1993-12-10
Granted: 1997-10-30
Abstract: PCT No. PCT/FR93/01232 Sec. 371 Date Jul. 23, 1995 Sec. 102(e) Date Jul. 23, 1995 PCT Filed Dec. 10, 1993 PCT Pub. No. WO94/13616 PCT Pub. Date Jun. 23, 1994Process for the treatment of a material comprising a polymer, especially a polyamide. The process consists in subjecting the polyamide to hydrolysis in the presence of a hydrolyzing nitrous grouping and transforming the hydrolyzed compounds into diacids. The treatment of a polyamide 6.6 results in the recovery of adipic acid and other diacids corresponding to the participating acid monomer and to the transformation of at least one part of the diamine monomer into diacids.
Patent DE-69313737-T2 (DE)
Inventor: TUUNANEN JUKKA
IPC: B01L3/02
Filed: 1993-06-22
Granted: 1998-03-26
Abstract: The invention relates to a motor-driven knob pipette, wherein the displacement of a slidably transferable knob (3) controls the movement of a piston (9) by means of an electronic control system. The pipette is light to use, and the user has continuosly a good motory feel with the pipette. <IMAGE>
Patent DE-69322061-T2 (DE)
Inventor: REUTER BRIAN T
IPC: G01L5/28
Filed: 1993-09-22
Granted: 1999-05-20
Abstract: A production functional test for hydraulic brake control and traction control units which utilizes compressed air as a test medium. Compressed air is applied to an external port of a hydraulic brake or traction control unit which includes valves, accumulators and a positive displacement pump driven by an electric motor connected by internal passageways. The air pressure at another external port is monitored while the various components are exercised according to a test sequence. The monitored pressure must be within predetermined limits at various points of the test to demonstrate that the brake control unit is functioning properly. Air flow rates and pump motor current are also measured at specific points in the test. The test method can identify incorrectly sized and installed components.
Patent DE-69325495-T2 (DE)
Inventor: MOONEY MARK T
IPC: A61L15/44
Filed: 1993-11-17
Granted: 2000-05-25
Abstract: An effective and convenient medicament delivery system comprising novel extrudable compositions. The preferred compositions of the invention contain a thermoplastic water-soluble polymer selected from the group consisting of hydroxypropyl cellulose and polyethylene oxide; a water-soluble polymer derived from acrylic acid; medicament; and plasticizer. The compositions provide an effective medicament delivery system and are especially suitable for use with adhesive bandages.
Patent DE-69330784-T2 (DE)
Inventor: MIYAZONO KOHEI
IPC: C07K1/22
Filed: 1993-01-19
Granted: 2002-05-23
Abstract: The invention relates to large latent complexes of TGF- beta 2 and TGF- beta 3, and methods for isolating these. The complex consists of a dimerized form of TGF- beta 2 or TGF- beta 3, the appropriate latency associated peptide, and the latent TGF- beta 1 binding protein, referred to as LTBP. Also described is a protein which binds to all of TGF- beta 1, TGF- beta 2 and TGF- beta 3, but is immunologically distinct from LTBP, referred to as LTBP-2.
Patent DE-69331459-T2 (DE)
Inventor: ESTES K
IPC: A61P31/12
Filed: 1993-07-12
Granted: 2002-06-20
Abstract: The invention relates to an improved rotavirus vaccine for man and animals and methods of using them. The invention comprises a method of immunizing humans, particularly children, and animals against rotavirus infections by parenteral immunization. The immunization may be carried out in a series of injections using live or inactivated vaccines, alone or in combination with each other or in combination with a rotavirus subunit vaccine or oral vaccine.
Patent DE-69332770-T2 (DE)
Inventor: VAZQUEZ MICHAEL L
IPC: C07C317/44
Filed: 1993-10-29
Granted: 2004-02-12
Abstract: Sulfonylalkanoylamino hydroxyethylamino sulfamic acid compounds are effective as retroviral protease inhibitors; and in particular as inhibitors of HIV protease.
Patent DE-69332987-T2 (DE)
Inventor: CHRISTENSEN SIEGFRIED B
IPC: A61K31/425
Filed: 1993-03-05
Granted: 2004-05-19
Abstract: Novel compounds of Formula (I) <CHEM> are described herein. These compounds inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production. The compounds of the present invention are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV and are therefore useful in the treatment of disease states in need of mediation or inhibition thereof.
Patent DE-69333631-T2 (DE)
Inventor: AKAOGI TAKAO
IPC: G11C16/04
Filed: 1993-06-25
Granted: 2005-02-03
Abstract: A semiconductor memory device having electrically erasable nonvolatile memory cells to and from which data is automatically written and erased according to an internal algorithm incorporated in said semiconductor memory device. The allowable value of write or erase operations is determined according to the internal algorithm, which is variable. Thus, a device embodying the present invention can carry out a delivery test with "n" rewrite operations at the most, and taking into account deterioration due to an increase in the number of rewrite operations, can guarantee the maximum number of rewrite operations N (N>n) possible by a user. <IMAGE>
Patent DE-69400981-T2 (DE)
Inventor: ETESSE PATRICK JEAN-FRANCOIS
IPC: B65D30/00
Filed: 1994-04-12
Granted: 1997-05-28
Abstract: A flexible, self-standing pouch (1) and a method for making the same. Said pouch has a top (2) and a base portion (3) comprising a front wall (4), a back wall (5) and a base wall(6). The pouches according to the present invention comprise peripheral edges in said base portion which are oblique. <IMAGE>
Patent DE-69405251-T2 (DE)
Inventor: TAI WAI FEI DAVID
IPC: G01N33/68
Filed: 1994-12-09
Granted: 1998-02-05
Abstract: PCT No. PCT/US94/14282 Sec. 371 Date Feb. 27, 1995 Sec. 102(e) Date Feb. 27, 1995 PCT Filed Dec. 9, 1994 PCT Pub. No. WO95/16203 PCT Pub. Date Jun. 15, 1995Provided are methods for the diagnosis of allergic disease wherein IgE specific for an allergen of interest is detected in a patient serum sample by using the patient serum sample to sensitize in the presence or absence of an IgE antagonist a mast cell or basophil host genetically engineered to display surface expression of a Fc epsilon RI subunit that is capable of mediating the host cells release of a pharmacological mediator upon induction with patient serum and allergen, challenging the sensitized host cells with the allergen of interest, and determining the presence or absence of IgE specific to the allergen of interest in the patient serum sample by comparing the release of the pharmacological mediator produced by host cells sensitized with patient serum in the presence of the IgE antagonist to the release of the pharmacological mediator produced by host cells sensitized with patient serum in the absence of the IgE antagonist.
Patent DE-69415001-T2 (DE)
Inventor: ZHANG LIN-HUA
IPC: C07K14/75
Filed: 1994-03-28
Granted: 1999-05-06
Abstract: This invention provides processes for the synthesis of platelet glycoprotein IIb/IIIa inhibitors and intermediate compounds useful in said processes. The compounds afforded by this invention have the formula:    <IMAGE>  Formula (I)