baber/WOPTO huggingface dataset:
Patent CA-2422774-C (CA)
Title: Remede contre la sclerose laterale amyotrophique
Inventor: FUNAKOSHI HIROSHI
IPC: A61K38/19
Filed: 2001-02-28
Granted: 2013-07-30
Abstract: L'invention concerne des remèdes (inhibiteurs de progression) contre la sclérose latérale amyothrophique (SLA) contenant en tant que principe actif HGF et/ou un gène HGF. Le HGF (facteur de croissance des hétapocytes) présente deux fonctions, c'est-à-dire, une activité de facteur neurotrophique directe sur les motoneurones et un effet indirect de soulagement de la cytotoxicité de l'acide glutamique sur les motoneurones par maintien du niveau de transporteur d'acide glutamique dans les astrocytes, améliorant ainsi la fonction motrice et prolongeant la durée de vie de patients atteints de SLA. Ainsi, le HGF et/ou le gène du HGF peuvent être utilisés efficacement en tant que remèdes efficaces inconnus jusqu'à présent.
Patent CA-2429463-C (CA)
Inventor: BELLAMY ANDREW MARTIN
IPC: C08G63/82
Filed: 2001-11-21
Granted: 2011-01-11
Abstract: A catalyst composition for producing polyesters comprises (a) a compound obtained by reacting a titanium, zirconium or aluminum alkoxide with an alcohol having at least two hydroxyl groups or a 2-hydroxy carboxylic acid in the presence of a base, and (b) at least one compound comprising germanium, tin or antimony. Polyesters obtained by esterification using this catalyst are disclosed, as are textiles, fibers, films, rigid packaging, and other articles made using the polyester.
Patent CA-2431500-C (CA)
Inventor: VAN DER BURG SJOERD HENDRIKUS
IPC: A61K38/095
Filed: 2001-12-07
Granted: 2016-06-07
Abstract: The invention is concerned with epitopes derived from human papilloma virus, and peptides having a size of about 22-45 amino acid residues comprising minimal T cell epitopes. The invention further provides clinically relevant approaches for immunizing subjects against (Myco)bacterially and/or virally infected cells or tumor cells, and in particular against HPV. The invention demonstrates that peptide sequences of 22-35 amino acid residues in length can induce both peptide-specific CD8+ cytolytic cells and CD4+ T-helper cells.  Moreover, the invention demonstrates that vaccination with 22-35 residue long peptides results in a more vigorous CD8+ cytolytic T-cell response than vaccination with peptides of the exact minimal CTL epitope length. The invention further demonstrates that the intrinsic capacity of certain minimal CTL epitopes which instead of activating cytolytic effector cells tolerize these cytolytic cells, can be overcome by use of these 22-35 amino acid long peptides. The invention further provides clinically relevant approaches for vaccination and/or treatment of subjects against HPV. The invention also provides methods and uses suited to treat subjects suffering from progressive lesions and/or cervical cancer.
Patent CA-2435304-C (CA)
Inventor: PARODI JUAN CARLOS
IPC: A61F2/06
Filed: 2002-01-18
Granted: 2010-01-05
Abstract: An introducer for implanting a prosthesis in a junction of a main lumen and a branch lumen. The prosthesis comprises a trunk to be implanted within the main lumen and at least one arm to be implanted within the branch lumen. The introducer comprises an outer sheath, an axial guide wire and at least one peripherical guide wire slideable within the outer sheath, and a nose cone at a distal end of the sheath. The nose cone has an axial conduit for receiving the axial guide wire and at least one peripheral channel for guiding the peripheral guide wire and guiding it into the branch lumen. A unitary branched prosthesis having at least one radial arm may be deployed using this introducer. Methods for deploying a unitary or modular branched prosthesis at a junction in a lumen use the introducer of this invention.
Patent CA-2436314-C (CA)
Inventor: HERBERT DAVID E
IPC: G05D16/20
Filed: 2003-07-31
Granted: 2008-09-30
Abstract: A solenoid operated three port pressure control valve assembly of the exhaust pressure bleed type. The valve for the inlet: pressure supply port includes a pressure responsive diaphragm with the supply port obturator attached. A bleed orifice in the diaphragm provides viscous dampening of the movement of the obturator and minimizes inlet valve flutter. The valve assembly is disclosed in both normally open and normally closed configurations.
Patent CA-2437785-C (CA)
Title: Hiv inhibiting pyrazinone derivatives
Inventor: KOYMANS LUCIEN MARIA HENRICUS
IPC: C07D241/20
Filed: 2002-03-13
Granted: 2009-05-12
Abstract: This invention concerns compounds of formula (I) (see formula I) a N-oxide, a pharmaceutically acceptable addition salt, or a stereochemically isomeric form thereof; their use as a medicine for inhibiting HIV replication, their processes for preparation and pharmaceutical compositions comprising them.
Patent CA-2441726-C (CA)
Inventor: RICHARDSON TIMOTHY M
IPC: G02B21/06
Filed: 1999-02-24
Granted: 2004-10-26
Abstract: A novel illuminator for a field microscope, which takes the place of the condenser and the light source and collimating optics in a traditional microscope, is described. The illuminator is described in several embodiments which cover bright-field transmitted light, bright-field reflected light, dark-field transmitted light and dark-field reflected light as well as uni-directional oblique and slit-ultra illumination techniques. The light sources are modular so that they can be interchanged on the microscope, and they feature ultra-low power and current consumption, integral dimming control, battery power and light weight. Optically the illuminators offer extremely flat field illumination along with excellent colour correction or selectable narrow wavelengths. The illuminators are characterized by high optical efficiency and small size.
Patent CA-2442383-C (CA)
Title: Method and apparatus for header compression in a wireless communication system
Inventor: HSU RAYMOND T
IPC: H04L12/56
Filed: 2002-03-28
Granted: 2012-05-29
Abstract: Method and apparatus for header compression in a wireless communication system supporting broadcast transmissions. The system periodically provides a header decompression message sufficient for a receiver to decompress the header. The decompression message transmission period is determined to avoid delay in accessing a broadcast session.
Patent CA-2445068-C (CA)
Title: Azo compounds for type i phototherapy
Inventor: RAJAGOPALAN RAGHAVAN
IPC: A61P9/10
Filed: 2002-04-18
Granted: 2010-09-21
Abstract: Novel azo compounds of Formula I:    (see formula I) Formula I     and their bioconjugates for phototherapy and/or photodiagnosis of tumors and other lesions. The azo derivatives of the present invention are designed to absorb at the low-energy ultraviolet, visible, or near-infrared (NIR) region of the electromagnetic spectrum. The phototherapeutic effect is caused by direct interaction of free radicals, the reactive intermediate produced upon photoexcitation of the azo compound, with the tissue of interest.
Patent CA-2446916-C (CA)
Inventor: RABINOWITZ JOSHUA D
IPC: F24V30/00
Filed: 2002-05-21
Granted: 2009-12-22
Abstract: The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of an opioid. In a method aspect of the present invention, an opioid is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of an opioid, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering an opioid through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of an opioid; and, b) a device that forms an opioid aerosol from the composition, for inhalation by the mammal.
Patent CA-2456224-C (CA)
Inventor: HEDHLI LOTFI
IPC: H01M8/02
Filed: 2004-01-26
Granted: 2012-01-24
Abstract: A non-perfluoropolymer is described which contains at least one acrylic resin or vinyl resin having at least one ionic or ionizable group and optionally at least one additional polymer. Preferably, the polymers are useful in a variety of applications including in the formation of a membrane which is useful in batteries and fuel cells and the like. Methods of making the polymer blends are also described.
Patent CA-2460513-C (CA)
Inventor: HARDWICKE JAMES JOHN
IPC: H04L12/24
Filed: 2002-09-24
Granted: 2010-09-14
Abstract: Un système de configuration de dispositifs réseau dans un réseau informatique présentant des applications particulières dans un environnement de partage de bureau met à jour, dans une base de données (110), aussi bien l'infrastructure IT du réseau que les relations structurelles et commerciales entre certains dispositifs en réseau, par exemple, l'information stipulant qu'un terminal d'ordinateur particulier (404) se situe physiquement dans le même bureau qu'un téléphone de réseau adjacent (406). Cette information permet au téléphone ou à d'autres dispositifs connexes en réseau d'être automatiquement configurés selon le profil prédéfini de l'utilisateur qui utilise ce poste de travail. Par ailleurs, l'invention permet de transmettre un service IT intégré et facile à mettre à jour quel que soit l'endroit choisi par l'utilisateur pour travailler dans le bureau.
Patent CA-2462186-C (CA)
Inventor: GUZMANN MARCUS
IPC: C11D17/04
Filed: 2002-09-23
Granted: 2010-06-29
Abstract: Process for producing a sealed water-soluble package of improved aesthetic appearance by treating at least part of the outer surfaces of the sealed package with a plasticizer composition and applying heat thereto, a package obtainable thereby and a specified use of such package.
Patent CA-2462205-C (CA)
Inventor: REINBOLD KLAUS
IPC: A46B7/06
Filed: 2002-10-03
Granted: 2008-01-08
Abstract: L'invention concerne une tête de brosse à dents comportant des éléments d'hygiène buccale élastomères se présentant sous la forme de bandes élastomères alignées de façon non perpendiculaire par rapport au sens longitudinal de la tête. De préférence, des paires adjacentes de bandes sont reliées de manière à former une bande de section transversale en V (32A, 32B). Par ailleurs, la tête comporte de préférence des segments reliés de façon flexible (14, 15), et est reliée de façon flexible au manche de la brosse à dents.
Patent CA-2464723-C (CA)
Inventor: PETTERSON TOR H
IPC: B65D83/28
Filed: 2002-10-30
Granted: 2007-03-13
Abstract: A valve assembly (32) is provided that automatically dispenses aerosol conte nt from a can (22) at predetermined intervals. A diaphragm (70) at least partially defines an accumulation chamber (71) that receives aerosol content from the can (22) during an accumulation phase. Once the internal pressure o f the accumulation chamber (71) reaches a predetermined threshold, the diaphra gm (70) flexes to initiate a spray phase, during which the aerosol content is delivered from the accumulation chamber (71) to the ambient environment. A rotatable pawl (78) provides resistive pressure and control of diaphragm movement.
Patent CA-2472145-C (CA)
Title: Dispositif regulateur de pression dans un recipient de distribution comprime
Inventor: FRASER-EASTON GILBERT
IPC: B05B9/047
Filed: 2003-01-30
Granted: 2007-09-25
Abstract: L'invention concerne un dispositif (10) de régulation de la pression destiné à réguler la pression dans un récipient de distribution comprimé (12). Ledit dispositif (10) comprend une cartouche (15) destinée à stocker du liquide comprimé. Ladite cartouche (15) est fermée par un ensemble bouchon (20) présentant une chambre extensible, un passage pour le flux, ainsi que des moyens d'activation dans l'ensemble bouchon (20) servant à ouvrir et fermer le passage du flux, en réponse à l'expansion de la chambre extensible. Ledit dispositif comprend également un clapet de non retour (24) faisant communiquer la chambre extensible avec l'intérieur dudit récipient de distribution (12) par l'intermédiaire d'un orifice (40) dans l'ensemble bouchon (20), ledit clapet (24) présentant un orifice de fermeture amovible de la chambre (35) dans la chambre extensible le long de l'ouverture (40) et il est retenu par la paroi de la chambre de façon à permettre au liquide d'entrer à travers l'orifice (40) et de passer l'orifice de fermeture (35) pour charger la chambre, à une différence de pression prédéterminée en dessous de la pression mesurée dans le récipient de distribution. L'expansion de la chambre se produit lorsque la pression dans le récipient de distribution (12) est plus faible que la pression dans la chambre.
Patent CA-2475904-C (CA)
Inventor: BARRITT WILLIAM D
IPC: F24C15/18
Filed: 2004-07-28
Granted: 2009-12-29
Abstract: A system used to program and coordinate the cooking operations for two or more ovens such that the cooking operations are completed at the same time, independent of particular setting variations. In accordance with a preferred embodiment of the invention, a single controller is utilized to program each of the ovens, with the controller incorporating an auto sequencing feature which causes the different cooking operations to be automatically performed, while terminating at the same time. Preferably, the system enables a second cooking operation to be programmed and initiated after a first cooking operation, while still providing for the auto sequencing of the cooking operation. Furthermore, a system is provided to enable the refrigerating of food items in one or more of the ovens prior to initiating a respective cooking operation.
Patent CA-2480844-C (CA)
Inventor: KITANO HAJIME
IPC: C08L33/00
Filed: 2003-04-21
Granted: 2010-10-19
Abstract: L'invention concerne une composition polymère comprenant (a) un polymère séquencé qui comprend un polymère séquencé (A) essentiellement constitué de .alpha.-méthylstyrène, et un polymère séquencé (B) éventuellement hydrogéné constitué d'un diène conjugué ou d'un isobutylène conjugué et présentant une masse moléculaire moyenne pondérale comprise entre 30 000 et 200 000; (b) une résine acrylique; et (c) un plastifiant dans des proportions (en masse) propres à satisfaire les relations (1) et (2): 0,05 <= Wb/Wa <= 2 (1) et Wc/(Wa + Wb + Wc) <= 0,5 (2); Wa, Wb et Wc représentant les contenus (en masse) des composants (a), (b) et (c), respectivement. La composition décrite dans cette invention présente d'excellentes propriétés, parmi lesquelles, l'aptitude au traitement par moulage, la résistance aux griffures, la résistance à l'usure, la souplesse, les résistances mécaniques, l'élasticité caoutchoutique, et la transparence; elle présente également un équilibre de ces propriétés; de plus, grâce à ses excellentes propriétés, elle peut être avantageusement utilisée dans divers domaines, tels que l'étirement d'un matériau, d'un laminé et d'une mousse.
Patent CA-2483580-C (CA)
Title: Biodegradable polymer for marking tissue and sealing tracts
Inventor: FISHER JOHN S
IPC: A61L24/00
Filed: 2003-04-03
Granted: 2010-09-14
Abstract: A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
Patent CA-2484271-C (CA)
Inventor: FUNDERBURK JEFFERY V
IPC: A61M5/00
Filed: 1998-12-18
Granted: 2007-04-24
Abstract: An insertion device (10) and insertion set (14). The insertion device (10) includes a device housing (28), a carrier body (30) and a driver (36). The carrier body (30) is slidably received within the device housing (28) for movement between an advanced position and a retracted position. The carrier body (30) also includes a receiving structure (32) to support the insertion set (14). The driver (36) urges the carrier body (30) with a controlled force and speed from the retracted position toward the advanced position to place at least a portion of the at least one piercing member (12) of the insertion set (14) through the skin of the patient to install the insertion set (14) to the patient. The receiving structure (32) of the carrier body (30) is removable from the insertion set (14).
Patent CA-2490969-C (CA)
Title: Method for updating singular value decomposition of a transfer matrix
Inventor: WILLINK TRICIA J
IPC: H04B7/04
Filed: 2004-12-22
Granted: 2014-06-17
Abstract: A method is disclosed for adaptively updating full or partial singular value decomposition (SVD) of a transfer matrix. The method employs orthogonal projections of known output and input vectors onto initial estimates of left and right singular vectors to compute corrections to the initial estimates of the singular vectors and singular values and adaptively generate updated estimates thereof. The method can be used for MIMO systems, including system of wireless MIMO communications employing adaptive transmitter and V- BLAST techniques.
Patent CA-2494553-C (CA)
Inventor: FAGO FRANK M
IPC: A61M5/44
Filed: 2003-07-21
Granted: 2011-04-19
Abstract: L'invention concerne un injecteur (20) pouvant être utilisé pour administrer un milieu de contraste radiographique et/ou une solution de perfusion dans le système vasculaire d'un patient à des fins diverses, telles que l'obtention de radiographies diagnostiques améliorées. Cet injecteur comprend les caractéristiques suivantes : (1) une monture de seringue (26) servant à attacher une seringue (28) à l'injecteur (20), (2) un affichage (34) et des commandes du volume et des débits, (3) une limitation automatique de la pression de fonctionnement de l'injecteur (20) telle que déterminée par la sélection d'un débit, (4) un berceau de seringue (48) doté d'une capacité de chauffage, (5) un dispositif de déclenchement de purge/de rétraction (36) permettant de commander la procédure d'injection à direction intuitive (à savoir, avancée pour l'injection, inversée pour le remplissage), une transmission de commande exempte de contact à travers le logement d'un injecteur (20) qui garantit une étanchéité améliorée, un blocage de la vitesse, et/ou la capacité de modifier la concentration et/ou le débit du milieu ou d'un autre fluide pendant l'injection, (6) un commutateur servant à déterminer lorsque le vérin (46) se trouve en position locale, (7) un commutateur de puissance de marche/d'arrêt <= flexible >= séparé de l'injecteur, et (8) une structure servant à empêcher la rotation du vérin (46) autour de son axe de symétrie (76). En outre, le système d'injecteur comporte un logiciel destiné au contrôle de divers composants.
Patent CA-2496201-C (CA)
Title: System and method for adaptive brake application and initial skid detection
Inventor: SALAMAT BIJAN
IPC: B60T8/60
Filed: 2003-07-14
Granted: 2010-05-11
Abstract: The adaptive brake application and initial skid detection system (10) allows rapid brake application and prevents deep initial skids. Brake torque is compared with a predetermined threshold brake torque. Wheel velocity error signals are also generated to indicated the difference between the wheel velocity and a reference velocity signal. A torque bias modulator integrator (20) responsive to brake torque signals adjusts the wheel velocity error signals to provide an anti-skid control signal (28). The torque bias modulator integrator (20) can also be initialized to the value of the measured brake torque when the wheel velocity error signals indicate the beginning of a skid. Brake torque difference signals are generated to indicate the difference between brake torque and a commanded brake torque, and an adjusted brake torque error signal (57) is generated in response to the brake torque difference signals.
Patent CA-2497883-C (CA)
Title: Method for distinguishing ulcerative colitis from crohn's disease by detecting the presence of fecal anti-neutrophil cytoplasmic antibodies (anca)
Inventor: BOONE JAMES HUNTER
IPC: C07K16/42
Filed: 2003-09-05
Granted: 2010-06-22
Abstract: A method and apparatus for the differentiation of ulcerative colitis from Crohn's disease and other gastrointestinal illnesses using the presence of anti-neutrophil cytoplasmic antibodies (ANCA) as a marker of ulcerative colitis is described. The apparatus consists of either a qualitative enzyme-linked immunoassay or other immunoassay that utilizes antibodies specific to human immunoglobulins for the measurement of total endogenous ANCA in a human sample. The method and apparatus can be used by healthcare providers to distinguish ulcerative colitis from Crohn's disease and other gastrointestinal.
Patent CA-2499578-C (CA)
Title: Modular lng process
Inventor: SAWCHUK JEFFREY H
IPC: F01D15/00
Filed: 2003-09-30
Granted: 2012-03-13
Abstract: Disclosed are methods for efficiently and economically designing, constructing, or operating a light hydrocarbon gas liquefaction process for the liquefaction of selected quantities of light hydrocarbon gas. The method includes a light hydrocarbon gas liquefaction launch train (15) to liquefy an initial amount of light hydrocarbon gas (59) and one or more optional subsequent modular expansion phases (115, 215) to said light hydrocarbon gas liquefaction train to liquefy additional selected quantities of light hydrocarbon gas (159, 259) up to a selected maximum quantity of light hydrocarbon gas for the process. The launch train includes facilities, such as light hydrocarbon feed gas prepretreatment facilities, refrigerant compression facilities, cryogenic heat exchange facilities, access services, other liquefaction equipment, and liquefied product storage and shipping facilities, At least a portion of these facilities are employed as shared use facilities.  The use of such shared use facilities allows for subsequent expansion phase or modules to be constructed to increase overall plant capacity, which can modules to be constructed to increase overall plant capacity, which can reduce the capital costs and space needed relative to prior methods for the design, construction, or operation of a light hydrocarbon liquefaction process which call for construction of a complete liquefaction train and all of its associated components and related equipment.
Patent CA-2499824-C (CA)
Inventor: KUWABARA NOBUYUKI
IPC: B41J2/175
Filed: 2003-09-29
Granted: 2009-12-08
Abstract: A liquid (ink) supply system having a closed structure with respect to an inkjet recording head is configured such that a gas hindering a recording operation and a liquid supply operation can be rapidly and smoothly eliminat ed from a liquid supply system without involving any complication in structure. An ink tank (10) and a liquid chamber (50) for leading ink supplied to the recording head (20) are brought into fluid communication via two communicati on channels (53 and 54). Thus, in the state where the gas exists inside the liquid chamber, the ink is moved from the ink tank (10) via one communicatio n channel (53), while the gas is transferred to the ink tank (10) via the othe r communication channel (54).
Patent CA-2503656-C (CA)
Inventor: MAK JOHN
IPC: B01D53/14
Filed: 2003-02-12
Granted: 2010-10-05
Abstract: On traite un gaz (1) comprenant du sulfure d'hydrogène, du dioxyde de carbone et des impuretés hydrocarbure dans une usine (Fig. 2) agencée de sorte que des flux de déchets soient recyclés jusqu'à extinction. Dans un des aspects particulièrement préférés de ces procédés et de ces agencements, le sulfure d'hydrogène et d'autres éléments sulfureux sont transformés en soufre (37), le dioxyde de carbone (44A) est séparé à un niveau de pureté suffisant pour améliorer la récupération ou la vente d'huile, et les impuretés hydrocarbure sont purifiées en un produit hydrocarbure (49) négociable sur le marché.