baber/WOPTO huggingface dataset:
Patent AU-2020217395-A1 (AU)
Title: Methods for enhancing immunosuppressive therapy by multiple administration of alpha beta TCR -binding polypeptide
Inventor: BLANK GREGOR
IPC: A61K39/00
Filed: 2020-08-12
Abstract: The present disclosure is related to improved methods for use of a humanized binding polypeptide specific for 
the alpha beta T cell receptor (a -TCR). In particular, this disclosure relates to improved methods of use of a 
humanized anti-ap-TCR antibody, which is derived from the murine monoclonal antibody BMA031, in 
immunosuppressive therapy. Novel methods using humanized monoclonal antibodies and/or humanized 
monoclonal antibody fragments (e.g., anti-apTCR antibodies and/or fragments thereof) are also provided.  
Novel methods using repetitive administration of humanized monoclonal antibodies and/or humanized 
monoclonal antibody fragments (e.g., anti-apTCR antibodies and/or fragments thereof) to reduce p T cells in 
the subject relative to 76 T cells in the subject are provided.
Patent AU-2020232773-A1 (AU)
Title: Percutaneous anti-microbiota formulations
Inventor: HOFFMAN STEVEN
IPC: A61K47/12
Filed: 2020-03-05
Abstract: The present disclosure is directed to percutaneous compositions containing an antiseptic, an antibiotic, an antifungal agent, an antihelminth agent, an antiviral agent, or an NSAID.
Patent AU-2020250209-A1 (AU)
Title: Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
Inventor: LEE HEEJIN
IPC: A61M31/00
Filed: 2020-10-07
Abstract: of the Disclosure 
Intravesical drug delivery devices are provided which may include an elongated body 
formed of a matrix system of a drug dispersed in a silicone, wherein the elongated body has a 
first end, an opposed second end, and an intermediate portion between the first and second 
ends, and wherein the silicone of the matrix system is cured to bias the elongated body in a 
coiled retention shape, such that the device is elastically deformable between a relatively 
straightened shape suited for insertion of the device through a urethra and into the urinary 
bladder of a patient and the coiled retention shape which is suited to retain the device within 
the urinary bladder.
Patent AU-2020267068-A1 (AU)
Title: Novel pharmaceutical composition
Inventor: ABE Michiaki
IPC: A61P13/12
Filed: 2020-04-24
Abstract: The present invention relates to a pharmaceutical composition that is used for treating or preventing acidosis of chronic kidney disease with anemia and contains citric acid, a pharmaceutically acceptable salt of citric acid, a hydrate thereof, or a mixture thereof, wherein the pharmaceutical composition is in the form of a tablet.
Patent AU-2020316336-A1 (AU)
Title: System and method for selecting a frequency to boost in a repeater
Inventor: LOTTER MICHIEL PETRUS
IPC: H04B7/15
Filed: 2020-07-17
Abstract: A method includes receiving, at a wireless signal booster, wireless signals on two or more frequencies; interrogating, by the wireless signal booster, a mobile device to retrieve a frequency of operation of the mobile device, the mobile device connected to the wireless signal booster using a first wireless communication connection, the mobile device connected to a network using the second wireless communication, wherein the mobile device provides a frequency of the network in response to interrogation by the wireless signal booster; selecting, based on the retrieved frequency, one selected frequency from the two or more frequencies; and selectively boosting, by the wireless signal booster, the wireless signals of the selected frequency, the selectively boosting repeating the wireless signals from the selected frequency in a boosted state for a mobile phone recipient. Related systems, apparatus, articles, and techniques are also described.
Patent AU-2020337333-A1 (AU)
Title: IgM glycovariants
Inventor: KEYT BRUCE
IPC: A61K39/395
Filed: 2020-08-21
Abstract: This disclosure provides an isolated IgM-derived binding molecule,
Patent AU-2020341814-A1 (AU)
Title: Freezing system for electronic mobile device repair
Inventor: HAJIPETROU GEORGIOS CHRISTODOULOY
IPC: F25D11/02
Filed: 2020-09-04
Abstract: A system utilized for freezing parts of electronic mobile devices comprises a freezing machine incorporating internet communication hardware and software, molds and vacuum bags and a central computer server hosting and operating a web-centric and/or mobile app software application which connects to, updates and operates the freezing machine via the Internet. The freezing machine comprises a housing, an engine with cylindrical cooling head, an adjustable cooling head ring fixture and metal plate attached to the adjustable cooling head ring fixture. The freezing machine further comprises an encapsulation chamber, a lid, a power inlet, a LCD/OLED display and a PCB with processor capable of operating the freezing machine.
Patent AU-2020363658-A1 (AU)
Title: Efficient back passivation crystalline silicon solar cell and manufacturing method therefor
Inventor: ZHANG PENG
IPC: H01L31/0216
Filed: 2020-08-13
Abstract: An efficient back passivation crystalline silicon solar cell and a manufacturing method therefor. The cell comprises an Ag gate finger electrode (1), a SiNx passivation antireflection layer (2), an N+ layer (a phosphorus doped layer) (3), P-type silicon (4), a back passivation layer (5), and an Al gate finger electrode (6) which are connected sequentially from top to bottom. The Ag gate finger electrode (1) sequentially penetrates through the SiNx passivation antireflection layer (2) and the N+ layer (3) and is connected to the P-type silicon (4) by means of an N++ layer (a heavily doped silicon layer) (7). The Al gate finger electrode (6) penetrates through the back passivation layer (5) and is connected to the P-type silicon (4) by means of a P+ layer (local contact aluminum doped layer) (8). The back passivation layer (5) is of a passivation antireflection laminated structure, and the passivation antireflection laminated structure (5) comprises a SiO2 passivation layer (51), an AlOx passivation layer (52), a SiNx antireflection layer (53), and a SiOxNy antireflection layer (54) which are sequentially provided from top to bottom. The solar cell has high carrier selectivity, high temperature stability, an excellent interface passivation effect, and excellent PID resistance, thereby achieving high conversion efficiency and high stability.
Patent AU-2020366718-A1 (AU)
Title: Sensor determination
Inventor: GASKELL MATTHEW ALASTAIR
IPC: A61B5/107
Filed: 2020-10-15
Abstract: Disclosed is a method for determining an unworn state of a sensor system comprising a pair of sensors configured for mounting on first and second body parts either side of a joint. The method comprises: obtaining one or more measurements from each sensor; calculating a relative angle between the two sensors using one or more of the obtained one or more measurements; calculating, using one or more of the obtained one or more measurements, a joint angle between the first and second body parts, where the joint angle is defined in a plane of normal bending of the joint; and determining, based on the calculated angles, whether either of the sensors is not mounted and if so, determining that the system is in an unworn state. Also disclosed is a system for providing information about a joint.
Patent AU-2020372832-A1 (AU)
Title: 4-Amino-imidazoquinoline compounds and use thereof
Inventor: CHOU YU-CHENG
IPC: C07D471/14
Filed: 2020-10-20
Abstract: 4-Amino-imidazoquinoline compounds and use thereof are disclosed. The compounds of the invention are Toll-like receptor 7 (TLR7) and TLR8 dual agonists, which exhibit activities in inducing IL-12 and IP-10 expression without over-inducing IL-6. The TLR 7/8 dual agonists are potentially useful medications as immune response modifiers. Use of a compound or salt thereof according to the invention in the manufacture of a medicament for treating a disease or a condition wherein activation of TLR7 and/or TLR8 provides a benefit in a subject in need thereof is disclosed. A compound or a pharmaceutical composition for use in treating a viral infection, cancer, and/or an allergic disease, or for use in activating immune responses that are effective against a viral infection, a tumor, and/or an allergic disease in a subject in need thereof is also disclosed.
Patent AU-2020393188-A1 (AU)
Title: An agricultural adjuvant
Inventor: MONTEIRO SARA ALEXANDRA VALADAS SILVA
IPC: A01N25/04
Filed: 2020-11-26
Abstract: This disclosure relates to an agricultural adjuvant comprising at least one polyphenol containing natural or synthetic oil composition where this oil includes blackcurrant
Patent AU-2020412433-A1 (AU)
Title: A monowheel system
Inventor: CAHAN AMOS
IPC: B60B1/02
Filed: 2020-12-22
Abstract: Coordinated movement transformable monowheel system formation generating electro- magnetic induction power, including an automatic transformable configuration in case of an actual or impending accident in order to minimize impact to a user, or in order to enhance the comfort level of a user.
Patent AU-2020415482-A1 (AU)
Title: Hull structure
Inventor: MARIOTTI MASSIMO
IPC: B63H21/30
Filed: 2020-12-22
Abstract: Hull structure made of composite material that includes a hull with high thickness "single skin" monocoque plating without reinforcements and an internal stiffening structure (1) formed by a deck (2), two opposing transverse bulkheads (3) and more cradle-shaped load-bearing elements (5) to support components or machinery intended to be housed on board said hull structure. Advantageously, the above-mentioned cradle-shaped load-bearing elements (5) are supported at the respective internal portions of said opposite transverse bulkheads (3) only at their opposite head ends (5b).
Patent AU-2020452061-A1 (AU)
Title: Method of controlling propulsion system of marine vehicle and propulsion system
Inventor: NUUTINEN MIKA
IPC: B63H1/10
Filed: 2020-06-11
Abstract: A method of controlling a propulsion system (102) of a marine vehicle (100) by a controller (112), which forms data on a pitch angle (
Patent AU-2020455277-A1 (AU)
Title: Application of methioninase gene therapy in treatment of malignant tumor
Inventor: Zhao Allan Zijian
IPC: A61K35/18
Filed: 2020-07-29
Abstract: Disclosed is an application of methioninase gene therapy in the treatment of a malignant tumor. In the gene therapy, a virus is used as a vector to insert an exogenous methioninase gene to constitute a methioninase expression system inside a tumor, thus providing an endogenous mechanism for further consumption of methionine. In vitro cytology experiments indicate that the methioninase gene therapy significantly reduces the level of intracellular methionine, effectively inhibits the proliferation of tumor cells, and can be used in an application in preparing a drug for the targeted treatment of a malignant tumor.
Patent WO-2021232099-A1 (WO)
Inventor: GANTIER MICHAEL PAUL MARIE
IPC: C12N15/117
Filed: 2021-05-19
Abstract: La présente invention concerne des oligonucléotides qui maintiennent une réponse de récepteur de type Toll 7 (TLR7) et/ou qui potentialisent la détection du récepteur de type Toll 8 (TLR8).
Patent AU-2021200317-A1 (AU)
Title: Bidirectional biomechanical prosthetic full finger configured for abduction and adduction with MCP pivot
Inventor: THOMPSON JR ROBERT
IPC: A61F2/76
Filed: 2021-01-19
Abstract: WO 
NONPROVISIONAL PATENT APPLICATION 
Abstract 
The disclosure provides apparatus and methods of use pertaining to a 
bidirectional biomechanical prosthetic finger assembly. In one embodiment, the 
assembly includes an eccentric metacarpophalangeal (MCP) pivot configured for 
swivelable attachment to a hand of a user, a distal coupler, and an articulation 
assembly rotatively coupled therebetween. A ring configured to receive a user's 
residual finger is disposed upon the articulation assembly, and may be adjusted to 
a target location based on a length of the residual finger. The articulation 
assembly is configured to utilize vertical movements of the residual finger within 
the ring to articulate the distal coupler within a plane parallel to an x-z plane, and 
the MCP pivot is configured to utilize lateral movements of the residual finger 
within the ring to articulate the distal coupler within a plane parallel to an x-y 
plane. Other embodiments are also disclosed.
Patent AU-2021200340-A1 (AU)
Title: Dry pipe rehabilitation spincaster
Inventor: WALKER KEITH
IPC: F16L55/18
Filed: 2021-01-20
Abstract: DRY PIPE REHABILITATION SPINCASTER 
ABSTRACT 
A remotely controllable pipe rehabilitation device having a base, a water opening, a dry 
pipe rehabilitation material opening, a first pipe rotatably attached to the base and coupled to 
the dry pipe rehabilitation material opening, a motor, a drive member coupled to the motor 
and the first pipe, a rotatable delivery pipe located adjacent to a first portion of the base and 
coupled to the first pipe and having a nozzle, a water with a water outlet to rotate with the 
nozzle, a first hose from the first water opening to the second water opening, a second hose 
from the water outlet to the nozzle, and a remote control disposed remotely from the area to 
be rehabilitated, the remote control to allow a user to operably maneuver the motor into a 
desired lateral orientation.  
26
1/8 
C=C 
|- - ---1-
Patent AU-2021204434-A1 (AU)
Title: Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
Inventor: øRUM HENRIK
IPC: A61K48/00
Filed: 2021-06-29
Abstract: The present invention relates to splice switching oligonucleotides or splice switching 
oligomers (SSOs). The preferred SSOs according to the invention target exon 7 of 
TNFR1 (TNFRSF1A) or TNFR2 (TNFRSF1A) pre-mRNA, typically resulting in the 
production of TNFR variants which comprise a deletion in part or the entire exon 7 
respectfully. SSOs targeting exon 7 are found to result in a soluble form of the 
TNFR, which has therapeutic benefit for treatment of inflammatory diseases. The 
SSO's are characterized in that they are substantially incapable or incapable of 
recruiting RNaseH.
Patent AU-2021206644-A1 (AU)
Title: Novel dominant negative Fas polypeptides, cells comprising thereof and uses thereof
Inventor: KLEBANOFF CHRISTOPHER A
IPC: C07K14/705
Filed: 2021-01-06
Abstract: The present disclosure provides novel dominant negative Fas polypeptides comprising a first modification in the cytoplasmic domain and a second modification in the N-terminal region of human Fas. The present disclosure also provides cells comprising such novel dominant negative Fas polypeptides and an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)). Also provided are uses of the cells for treatment, e.g., for treating tumors and pathogen infections.
Patent AU-2021216117-A1 (AU)
Title: Inspection device and inspection unit
Inventor: DANILOV ANDREY
IPC: G01M3/24
Filed: 2021-02-05
Abstract: An inspection device for checking pipelines (8) comprising a sensor carrier (1) which can be rolled through the pipeline (8) during operation, is provided with an at least substantially circular circumference (4) in a section running perpendicularly with respect to a rotational axis (2), and has at least one sensor unit (3), wherein the sensor carrier (1) comprises at least one, preferably a plurality of stabilizing means (6) arranged along the circumference (4), and an inspection unit.
Patent AU-2021234316-A1 (AU)
Title: Method for treatment of COVID-19-associated conditions
Inventor: MASUDA ESTEBAN
IPC: A61K39/395
Filed: 2021-03-11
Abstract: Provided herein are a variety of methods that involve administering fostamatinib, an active component thereof or a pharmaceutically acceptable salt thereof to a patient. In some embodiments, the method may comprise administering fostamatinib, an active component thereof or a pharmaceutically acceptable salt thereof to a patient having or suspected of having a COVID-19 infection. In some embodiments, the method may comprise administering fostamatinib, an active component thereof or a pharmaceutically acceptable salt thereof to a patient having, suspected of having or expected to develop acute respiratory distress syndrome, acute kidney injury, and/or thrombosis. In some embodiments, the method may comprise administering fostamatinib, an active component thereof or a pharmaceutically acceptable salt thereof to a patient having, suspected of having or expected to develop symptoms associated with a cytokine response. Aspects of the methods may further include identifying a patient with kidney malfunction, e.g., acute kidney injury, and/or thrombosis.
Patent AU-2021236655-A1 (AU)
Title: Use of anti-IL-6 antibody, e.g., clazakizumab for treatment/prevention of ARDS associated with coronavirus (COVID-19) infection
Inventor: MONTGOMERY ROBERT
IPC: A61P29/00
Filed: 2021-03-17
Abstract: The present disclosure relates to uses of an anti-IL-6 antibody, e.g., clazakizumab in order to prevent, stabilize, reduce, or otherwise treat acute or chronic respiratory distress syndrome (ARDS or CRDS) and symptoms thereof such as lung damage, and also to treat cytokine storm syndrome, in patients with or suspected of having a bacterial, viral, or fungal infection, such as a coronavirus infection, e.g., COVID-19, SARS, MERS, or another bacterial or viral infection which may cause acute or chronic respiratory distress syndrome or cytokine storm syndrome.
Patent AU-2021239822-A1 (AU)
Title: Combination therapy for acute myeloid leukemia
Inventor: BUCHHOLZ TONIA J
IPC: A61K31/5377
Filed: 2021-03-12
Abstract: Provided herein are methods of treatment of AML comprising administering 2-(4- chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-5-yl)methyl)-2,2- difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, co-crystal, clathrate, or polymorph thereof in a combination therapy.
Patent AU-2021240334-A1 (AU)
Title: Amino acid derivatives and their uses
Inventor: GAMBOGI ROBERT J
IPC: C07C237/06
Filed: 2021-10-05
Abstract: Provided are compounds described by the Formula I: 
R2 
0 ( H 
R1 N N, R3 
H R 
0 
(I) 
wherein: R 1 is a linear or branched, saturated or unsaturated aliphatic group having from 5 to 22 
5 carbon atoms; R2 is selected from the group consisting of the functional groups: 
-NH2; 
-NH 
>-NH 
H2N 
and salts thererof; n is from 0 to 4; and R3 is a linear or branched, saturated or unsaturated 
aliphatic group having from 1 to 6 carbon atoms. Also provided are compositions comprising, 
0 and methods of use of, the compounds of the present invention.
Patent AU-2021258740-A1 (AU)
Title: Electric motors and methods of controlling thereof
Inventor: BUSSIERES NORMAND
IPC: H02K11/21
Filed: 2021-04-26
Abstract: Electric motors and methods of controlling electric motors are described herein. The electric motors include a mobile component having at least one permanent magnet coupled thereto and a stator spaced apart from the mobile component. The stator includes at least one stator pole having a ferromagnetic core and a coil wrapped around the ferromagnetic core. The ferromagnetic core is naturally attracted to the at least one permanent magnet. The motors also include a magnetic position control system configured to monitor a position of the at least one permanent magnet relative to the stator and controllably deliver an electric pulse to the coil of each stator pole to generate a repulsive magnetic flux on the ferromagnetic core to cancel an attraction force between the ferromagnetic core and the at least one permanent magnet to control movement of the mobile component.
Patent AU-2021265124-A1 (AU)
Title: Methods to generate vaccine compositions that prime human leukocyte antigen class I restricted CD8 T-cell responses against viral non-virion-integral derived epitopes
Inventor: JARVIS REAGAN MICHEAL
IPC: A61P31/14
Filed: 2021-04-27
Abstract: Method for providing a vaccine composition capable of effectively inducing a systemic immune response and/or a localised immune response upon administration, wherein the composition comprises human leukocyte antigen class I (HLAI) -restricted epitopes selected from viral pathogen non-virion-integral proteins (non-VIP) and thus prime a CD8 T-cell response specifically directed against virally infected cells.
Patent AU-2021295668-A1 (AU)
Title: Provisioning medical resources triggered by a lifecycle event
Inventor: KETCHEL III PAUL J
IPC: G16H40/20
Filed: 2021-03-31
Abstract: Apparatus and associated methods related to determining medical services appropriate to a patient in response to a patient lifecycle event: presenting the medical services to the patient for selection; optionally scheduling the selected medical services; and automatically presenting the selected services for prepayment. The patient lifecycle event may be, for example, a doctor's order, diagnosis, condition change, payment, admission, or discharge. The services presented to the patient may be determined in response to, and as a function of, the lifecycle event. For example, the services presented may include procedures determined after the lifecycle event, in view of patient medical history. In an illustrative example, the services presented may be based on medical indication, contraindication, provider or facility availability, or patient scheduling preference, advantageously permitting more medically relevant, beneficial, convenient, or cost-effective services. Various examples may advantageously provide a discount for a service bundle provided at a particular time or facility or by an affiliated physician or medical group.
Patent AU-2021299172-A1 (AU)
Title: A front loader for a working vehicle and a working vehicle
Inventor: NILSSON TOMMY
IPC: E02F3/627
Filed: 2021-06-23
Abstract: The invention relates to a front loader (10) comprising: at least one fastening arrangement (12) connectable to a working vehicle (1); at least one loader arm (20) with a first part (21) and a second part (22) connected via a knee section (23), the first part (21) being pivotally connected to the fastening arrangement (12) at a pivot point (P1); a tool attachment (14) device connected to the second part (22) of the at least one loader arm (20); at least one tilting cylinder (16) connected to the tool attachment device (14) and to a knee link (30) arranged at the knee section (23), wherein the knee link (30) comprises a first attachment point (31) for connection with the tilting cylinder (16), a second attachment point (32) for connection with the loader arm (20), and a third attachment point (33) for connection to a mechanical self-levelling device (50), wherein the knee link (30) is arranged at the knee section (23), such that the first attachment point (31) is essentially aligned with or below an upper end (24) of the first part (21) of the loader arm (20).
Patent AU-2021306386-A1 (AU)
Title: Methods, first service request terminals, systems, and electronic devices for information display
Inventor: ZHANG TIHUI
IPC: G06Q50/30
Filed: 2021-07-07
Abstract: An information display method, a first service request terminal, a system and an electronic device. A service request position of a first service requester is acquired when a carpooling request from the first service requester is received (S201); dynamic carpooling information during the carpooling process of a second service requester within a preset distance range of the service request position of the first service requester is determined (S202); the dynamic carpooling information of the second service requester is displayed on a display interface of the first service request terminal (S203). Thus, during the time period when the carpooling request is awaiting a response, the dynamic carpooling information of the second service requester within the preset distance range of the service request position of the first service requester is displayed to the first service requester. Display content on the terminal can be effectively enriched, transparency of related information is enhanced, filling the idle waiting time for the user, and the probability of order cancellation can be reduced.