baber/WOPTO huggingface dataset:
Patent IL-188903-A0 (IL)
Title: N-oxides as prodrugs of piperazine & piperidine derivatives
Filed: 2008-01-21
Abstract: The present invention relates to N-oxides of certain piperazine and piperidine derivatives and to methods for the preparation of these compounds. The invention also relates to the use of compounds disclosed herein for the manufacture of a medicament giving a beneficial effect. A beneficial effect is disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. The invention also relates to the use of a compound of the invention for the manufacture of a medicament for treating or preventing a disease or condition. More particularly, the invention relates to a new use for the treatment of a disease or condition disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. In embodiments of the invention specific compounds disclosed herein are used for the manufacture of a medicament useful in the treatment of CNS-disorders, in particular the treatment of anxiety disorders, including generalized anxiety disorder and panic disorder, obsessive compulsive disorder, aggression, addiction (including craving), depression, autism, vertigo, schizophrenia and other psychotic disorders, Parkinson's disease and disturbances of cognition and memory. The compounds have the general formula (1) wherein the symbols have the meanings given in the specification.
Patent IL-192290-A0 (IL)
Title: Erythropoietin analogs
IPC: C07K19/00
Filed: 1994-08-15
Abstract: The following are new: (1) an analogue of human erythropoietin (hEPO) comprising a sequence including \-1 additional glycosylation site; (2) an analogue of hEPO comprising a sequence with re-arrangement of \-1 glycosylation site; (3) a DNA sequence encoding the hEPOs of (1) and (2); and (4) a eukaryotic host cell transfected with the DNA of (3).
Patent IL-210851-A0 (IL)
Title: Pharmaceutical formulation for contraception and hormone-replacement therapy
IPC: A61K9/00
Filed: 2011-01-25
Abstract: The invention provides a method for effecting simultaneous contraception and hormone replacement therapy in a female mammal comprising administering to said mammal a pharmaceutical formulation comprising particles of 17-²-estradiol and cholesterol in about a 1:1 molar ratio, and particles of progesterone; wherein the weight ratio of 17-²-estradiol to progesterone is about 1:40.
Patent RO-131816-A0 (RO)
Title: Haptic system for virtual palpation of liver and pancreas tumours, with tridimensional computerized reconstruction
Inventor: GHEONEA DAN IONUŢ
IPC: G06F3/00
Filed: 2016-11-28
Abstract: The invention relates to a haptic system for virtual palpation of hepatic and pancreatic tumours, meant to be used in medicine. According to the invention, the system comprises a central unit (1) which communicates with a CT scanner (2) or an ultrasound scanner provided with an elastography probe (3), and is capable to reconstruct in a computerized manner a tridimensional digital deformable tumour model (4) which uses the tumour shape, and to reproduce on the virtual surface created thereby the elasticity data of the tissue which are obtained by elastography, the results being displayed on a display system (5), a manual device (6) capable to interact with the virtual computerized model created by the central unit (1), which is provided with five rods (7) articulated in three points with stressed levers following the fingers anatomy, connected to some servo motors (8) controlled by the central unit, with five inflatable cushions (9) located at the tips of the rods and actuated by a miniaturized air-blowing system (10) located at the base of the user's hand, with a gyroscope (11) and a magnetic sensor (12) for position detection in relation with a fixed magnetic marker (13), where the said system combines space data obtained by computerized tomography with tumour tissue elasticity data obtained by transcutaneous elastography, reconstructing the tridimensional tumour and reproducing on its surface the tissue hardness, thereby establishing the deformability thereof.
Patent RO-134701-A0 (RO)
Title: Sealing device for siphons
Inventor: MESEŞAN DUMITRU
IPC: E03F5/10
Filed: 2020-09-17
Abstract: The invention relates to a simple and versatile sealing device for siphons, which is easy to maintain, by means of which it is possible to ensure the tightness of siphons that control the level of fluids in various enclosures, intended to be used both in individual households and in spaces meant for offices, medical consulting rooms, company offices or any other enclosures. According to the invention, the device consists of a sediments storage space (1) of cylindrical shape, with double wall, placed in the siphon, next to an outer body (3) of the siphon, having at its top a shoulder (4), on which a lid (5) of the siphon rests and being provided with a removable circular sieve (2), which retains impurities from the water.
Patent LU-73397-A1 (LU)
IPC: C07D301/26
Filed: 1975-09-15
Abstract: A novel process for the preparation of substituted trans-epoxy cis-alkenes of the formula OO   PARALLEL  PARALLEL CH3-(CH2)m-CH-CH-CH=CH-CH2-CH2-C-CH2-COAlk I  ANGLE  O  wherein Alk is straight or branched alkyl of 1 to 6 carbon atoms and m is 3,4 or 5 which are intermediates for prostaglandin compounds.
Patent MA-25811-A1 (MA)
Inventor: GREGORY SCOT MIRACLE
IPC: A61K8/00
Filed: 2002-11-29
Abstract: The present invention relates to sustained release fragrance accords wherein the initial fragrance release or bouquet is not distorted by the presence of an unbalanced accord. The systems of the present invention comprise:a) a pro-fragrance component; andb) a free fragrance component.The present invention further relates to compositions comprising the fragrance raw materials systems and processes for preparing said systems.
Patent MA-27959-A1 (MA)
Title: Compositions comprenant un agent complexant de graisse alimentaire et leurs procedes d'utilisation
Inventor: ARTISS JOSEPH D
IPC: A23P30/40
Filed: 2004-09-28
Abstract: La présente invention concerne des produits alimentaires consommables contenant des graisses et comprenant de l'$g(a)-cyclodextrine. Lesdits produits alimentaires présentent des niveaux réduits de graisse biodisponible mais présentent sensiblement la même teneur en graisse, en cholestérol et calorique qu'un aliment semblable sans $g(a)-cyclodextrine. L'invention concerne également des procédés de réduction de la biodisponibilité des graisses dans des produits alimentaires contenant des graisses sans réduction de l'apport calorique tel que déterminé par calorimétrie à l'aide d'une bombe, ainsi que des procèdes d'augmentation des lipoprotéines haute densité chez un sujet et de réduction ou de régulation du poids par administration des produits alimentaires selon ladite invention.
Patent MA-28132-A1 (MA)
Title: FORME CRISTALLINE GAMMAd DU CHLORHYDRATE DE L'IVABRADINE, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT.
Inventor: HORVATH STEPHANE
Filed: 2006-02-13
Abstract: FORME CRISTALLINE (gama) DU CHLORHYDRATE DE L'IVABRADINE, SON PROCEDE DE PREPARATION, ET LES COMPOSITIONS PHARMACEUTIQUES QUI LA CONTIENNENT Forme cristalline (gama)d du chlorhydrate de l'ivabradine de formule (I) : caractérisée par son diagramme de diffraction X sur poudre. Médicaments.
Patent MA-57761-A1 (MA)
Title: Appareils, systèmes et procédés de chauffage avec des ondes électromagnétiques
Inventor: BADAC JEFFREY
IPC: H05B6/80
Filed: 2021-02-04
Abstract: L'invention concerne des appareils, des systèmes et des procédés de chauffage d'un fluide ou d'un autre matériau. Les appareils peuvent comprendre un contenant (par ex., un tube) dans lequel est disposé un matériau suscepteur. Le matériau suscepteur peut convertir l'énergie micro-onde en chaleur, pouvant augmenter la température d'un fluide ou d'un matériau dans ou à proximité du tube.
Patent UY-25790-A1 (UY)
Title: Formas farmaceuticas de eritropoyetina humana recombinante estables a temperatura ambiente y apropiadas para su uso en humanos, formulaciones y procedimientos de liofilizacion para su obtencion.
Inventor: ALEJANDRO VIDAL
IPC: A61K47/02
Filed: 1999-11-05
Abstract: La peresente invención se refiere a formas farmacéuticas de Eritropoyetina (EPO) Humana Recombinante que se caracterizan porque: a) son estables a temperatura ambiente, b) son liofilizadas, c) son apropiadas para su uso en humanos y d) contienen un sacárido, NaCl, NaH2PO4, NaHPO4.12 H2O, albúmina humana, Eritropoyetina Humana Recombinante y agua. La EPO es una proteína que ha demostrado gran eficacia para el tratamiento de anemias. Las formulaciones reivindicadas contienen 1000 UI, 2000 UI, 4000 UI y 10000 UI de EPO con el agregado de excipientes específicos que aseguran la isotonicidad y estabilidad del producto.
Patent UY-27074-A1 (UY)
Title: Derivados de aminotriazolopiridina
Inventor: NETTEKOVEN M H
IPC: A61P11/00
Filed: 2001-12-14
Abstract: La invención describe compuestos de fórmula general: I. Y las sales de adición ácida farmacéuticamente aceptables en donde R1. R2 y X están definidos en la reivindicación I. Los compuestos tienen una buena afinidad por el receptor de adenosina y se pueden usar además en el tratamiento de enfermedades, relacionadas con este receptor.
Patent ZW-19380-A1 (ZW)
Title: Pesticidal compounds compositions and methods
Inventor: PALMER ANTONIN KOZLIK BRYAN HA
IPC: C07F9/06
Filed: 1980-08-18
Abstract: Substituted benzophenone hydrazones of formula I 
<CHEM>
 in which R, Q, R<2> and R<4> have the meaning given in the description. 
<??>The hydrazones have pesticidal activity, especially againct insects and acarids, and pesticidal compositions and methods are described. Methods of making the hydrazones are also described.
Patent AT-515840-A1 (AT)
Title: Verfahren zum Befüllen von fluiddynamischen Lagern mit Lagerfluid
Inventor: FUSS THOMAS
IPC: F16N37/00
Filed: 2014-02-07
Abstract: Die Erfindung betrifft ein Verfahren zum Befüllen eines fluiddynamischen Lagers (6) mit Lagerfluid mittels einer Befüllvorrichtung mit einer Vakuumkammer (1 0, 110, 210), mit den Schritten: Setzen des Lagers (6) unter Vakuum, Befüllen des Lagers (6) unter Vakuum in der Vakuumkammer, Setzen des Lagers (6) unter Atmosphärendruck, erneutes Setzen des Lagers (6) unter Vakuum, Durchlaufen einer Ruhephase im Vakuum, Setzen des Lagers (6) unter Atmosphärendruck.
Patent ES-173771-A1 (ES)
Title: UN MÉTODO PARA FABRICAR PERoXIDO DE HIDRoGENO
Filed: 1946-05-28
Abstract: El método para fabricar peróxido de hidrógeno concentrado y purificado que comprende una serie de etapas de destilación en cada una de las cuales se concentra sucesivamente la solución de peróxido por destilación con separación de las soluciones de residuo impuras y concentradas; siendo condensados y rectificados los vapores que se componen de peróxido de hidrógeno y agua para producir en cada etapa sucesiva soluciones que son simultáneamente de creciente concetración y de una pureza igualmente creciente.
Patent ES-179055-A1 (ES)
Title: SISTEMAS DE EXHIBICIoN
IPC: G08G5/00
Filed: 1947-07-23
Abstract: Sistema de exhibición para exhibir la posición y movimiento de naves con referencia a una posición dada que comprende una pantalla medios para producir una representación óptica de una nave medios para proyectar dicha representación sobre dicha pantalla medios para controlar dichos medios de proyección para mover dicha representación en la pantalla para representar el movimiento de dicha nave.
Patent ES-181324-A1 (ES)
Title: UNAS MEJORAS EN LOS FAROS MoVILES SOLIDARIOS CON LA DIRECCIoN DEL VEHiCULO
Filed: 1947-12-13
Abstract: Unas mejoras en los faros solidarios con la dirección del vehículo, caracterizadas por el hecho de sostener a cada uno de los faros cuya posición interesa variar automáticamente sobre un eje vertical fijo al chasis y capaz de girar sobre si mismo por al acción de una palanca radial articulada con una biela transversal desplazable lateralmente de acuerdo con los desplazamientos de la biela transversal de la dirección que une entre sí las dos ruedas delanteras; el hecho de que esta conexión se consiga gracias a otra palanca articulada con una y otra cuyo punto de apoyo se situa sobre el chasis y entre ambas bielas.
Patent ES-183650-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA CONSTRUCCIoN DE PISOS
Filed: 1948-05-11
Abstract: Un procedimiento par ala construcción de pisos caracterizado por estar formado en su conjunto por una serie de bovedilla formeros,colocadas una acontinuación otras a tope,por medio de unos tacos salientes que lleva en sus laterales, formándose entre ambas un hueco en el cual al forjar el piso, se formará un nervio o viga de unión que descansará entre los dichos tacos salientes que le servirán de solera base y entre cuyos costados de las bovedillas quedarán prisionera en su forjado por medio de unos huecos o canales que lleva en la forma y figura que se desee.
Patent ES-186699-A1 (ES)
Title: Un dispositivo para el cierres del rabillo de un tubo de descarga
Filed: 1949-01-20
Abstract: Un dispositivo para el cierre del rabillo de un tubo de descarga formado por un fondo discoidal en el cual van unidas herméticamente además del rabillo espigas de contacto caracterizado porque el tubo se dispone en un soporte metálico perforado con aberturas para las espigas de contacto y para el paso del rabillo y en esta última abertura desembocan una o más hendiduras radiales cuya anchura es al menos en una parte de la longitud menor que la separación de dos espigas de contacto y cada una de las cuales pasa directamente bajo el fondo del tubo y tiene al menos un tabique intermedio hendiduras a través de las cuales el rabillo es cerrado con ayuda de llamas a una distancia del tubo menor que la longitud de las espigas de contacto pudiendo presentar además este dispositivo las particularidades siguientes tomadas por separado o según las diversas combinaciones posibles. a) un tabique horizontal va dispuesto en una hendidura según la dirección longitudinal de ésta última; b) en el punto en que la hendidura desemboca en la abertura del soporte prevista para el paso del rabillo va colocada una pantalla perforada que a su vez va dispuesta verticalmente.
Patent ES-192388-A1 (ES)
Title: APARATO DE PERCUSIoN ACCIONADO MEDIANTE LA FUERZA CENTRiFUGA PRODUCIDA POR MASAS EXCENTRICAS GIRATORIAS
IPC: B25D11/12
Filed: 1950-12-31
Abstract: Aparato de percusión accionado mediante la fuerza centrífuga producida por masas excéntricas giratorias caracterizado porque el órgano oscilante de percusión sobre el cual se encuentra el asiento o los asientos para las masas giratorias tiene a lo menos un agujero axial del lado opuesto de la superficie de percusión siendo dicho agujero destinado al transporte del lubrificante sobre los asientos mismos.
Patent ES-198468-A1 (ES)
Title: UN PROCEDIMIENTO PARA SEPARAR COSTRAS CRISTALINAS DEPOSITADAS DURANTE EL ENFRIAMIENTO EN PARTES DE CRISTALIZACIoN U OTRO SIMILAR
Filed: 1951-06-23
Abstract: Un procedimiento para separar costras cristalinas que se depositan durante el enfriamiento en partes de un dispositivo de cristalización o similar caracterizado porque el chorro de gas va dirigido periódicamente en dichas partes.
Patent ES-280463-A1 (ES)
Title: Methods of preservation using pharmaceutical compositions comprising iodolium and bromolium cations
IPC: A61K39/00
Filed: 1962-09-01
Abstract: The invention comprises: (i) the hydroxide, (ii) the carbonate, (iii) the propionate, (iv) the butyrate, (v) the cyclopropanecarboxylate, (vi) the tartrate, (vii) the citrate, (viii) the malonate, (ix) the methanesulphonate and (x) the isethionate of the dibenziodolium cation: <PICT:1013571/C2/1> They may be prepared by conventional methods.ALSO:Materials susceptible to damage by contaminating micro-organisms, in particular vaccines, are preserved by adding thereto small quantities (eg. 1 part to 1000-100000 parts by weight) of a salt of the dibenziodolium or dibenzbromolium cation with an acceptable organic or inorganic anion, the said cations having the formulae <FORM:1013571/A5-A6/1> (I) <FORM:1013571/A5-A6/2> (II) Specified vaccines are those containing living bacterial spores eg. those of Bacillus anthracis and killed clostrident vaccines eg. those containing Clostridium botulinum, C. chauvoei, C. oedematiens, C. perfringens (types B, C and D), C. Septicum and C. tetani. The inventions further comprises pharmaceutical bacteriostatic compositions for topical use comprising a carrier and a dibenziodolium or dibenzbromolium salt e.g. in the form of a lotion, cream, jelly, ointment, tincture or eardrops.
Patent ES-290518-A1 (ES)
Title: Preparation of -aminobenzylpenicillin and salts thereof
IPC: C07D499/68
Filed: 1963-08-01
Abstract: a -Aminobenzylpenicillin, or a non-toxic salt thereof, is produced by reacting a -bromobenzylpenicillin, or a non-toxic salt thereof, with hexamethylene tetramine. Specified salts are the sodium, potassium, calcium, aluminium, ammonium and substituted ammonium salts, e.g. salts of triethylamine procaine, dibenzylamine, N-benzyl-beta-phenethylamine, lephenamine, N,N1-dibenzylethylenediamine, dehydroabietylamine and N,N1-bis-dehydroabietylethylenediamine. The a -aminobenzylpenicillin is an antibacterial agent for human and animal use, e.g. mastitis in cattle, and is a nutritional supplement in animal feeds. Specifications 873,049 and 880,042 are referred to
Patent ES-314862-A1 (ES)
Title: Method and apparatus for manufacturing sheet metal central heating radiators
IPC: B21D53/04
Filed: 1965-07-01
Abstract: Sheet metal strips 11, 12 pass through a reciprocating press 24, comprising a punch member 38, a reciprocable member 40 having a die and a punch on its top and bottom faces respectively and a fixed die member 39, to form transverse ducts (13) and conduits (14) in each strip (Fig. 1, not shown). The strips 11, 12 are looped upwards to allow some slack for the intermittent feed. Rolls 21, 22 are intermittently driven by an electric motor M1 which is controlled by a micro-switch S1 to maintain the appropriate slack. A feed mechanism 25 draws the strips through the press 24 and advances the formed strips to a spot welding apparatus 26, which comprises a row of hydraulic cylinders 47 each carrying an electrode 48 to weld the panels at portions (15) (Fig. 1) when the press 24 is closed. The panels pass to severing means 27 comprising two highspeed cutter discs 52 which cut through the conduits (14), and a shear at station 27B, which severs the panel. The severed panel drops on to a conveyer 28 thereby triggering a micro-switch to return a carriage to a rearward position to latch catches 72 against the trailing edge of the panel. The carriage triggers a second micro-switch to start its forward move and the panel thereon pushes the preceding panel through a welder 29, which seam welds the edges (17) (Fig. 1) between welding discs 291. The seam welded panel P passes to conveyer means (75) (Fig. 9, not shown) in which the panel is brought to a vertical position by rams (80) and moved transversely by a ram (83) on to guide rolls (86) which may accommodate a plurality of panels. The panel is advanced to an edge weld station (76) where the edge to be welded is held in an hydraulically operated clamp (87) which prevents distortion as a welding head (91) traverses the edge of the panel. The trailing edge of the panel may be simultaneously welded in a similar clamp. The welder may be of the inert gas shielded short circuiting arc type. Reference has been directed by the Comptroller to Specification 932,324.
Patent ES-320673-A1 (ES)
Title: Method for filling loom shuttles with cut-to-length pieces of weft thread and apparatus for the performance of the aforesaid method
IPC: D03J3/04
Filed: 1965-12-06
Abstract: A continuously moving weft is blown into one end of the hollow body of a shuttle for a loom of the travelling wave shedding type, is held after it emerges from the other end and is cut after a predetermined length has accumulated in the body, weft is delivered by rolls 43 to a feeding device comprising cooperating stationary and rotary heads 26, 25 respectively, mounted above a wheel 40 rotating with head 25 and turning shuttle 42 through 180 at the end of the shed. It blown down channel 20 into one of several channels 28, having a wide aperture at its upper end, in the head 25 and through tube 39 into a shuttle. The end of the weft projecting from the shuttle is clamped by spring arm 8 engaging shuttle flap 16, allowing weft to accumulate. The weft is cut 'between the ends of relatively moving channels 20, 28, the end blown into the shuttle and the moving weft now blown into the following shuttle. When the shuttle leaves the wheel flap 16 closes its end, and arm 8 is re-flexed mechanically or electromagnetically. The amount of thread delivered may be varied by adjusting the roll speed, or displacing the yarn axially of conical rolls.
Patent ES-334354-A1 (ES)
Title: Alcohol-soluble color salts
IPC: C09B45/14
Filed: 1966-12-10
Abstract: The invention comprises alcohol-soluble colour salts comprising a dyestuff anion moiety which is the anion of a Cr or Co complex of an at least tridentate complex-forming azo dyestuff, which contains no groups which dissociate acid in water and do not take part in the complex formation, and an ammonium alkyl-polyalkyl-polyhydrophenanthrene. Preferred anionic Cr or Co compounds for use in the above process are those containing per Cr or Co atom either two tridentate complex-forming azo dyestuff molecules or one molecule of a more than tridentate complex-forming azo dyestuff, e.g. a tetradentate-complexing azo dyestuff, preferably in combination with one bidentate ligand free from chromophoric groups. Preferred amino-alkyl-polyalkyl-polyhydrophenanthrenes are dehydro-, dihydro- and tetrahydro-abietylamine. Examples are given for the production of the salts. Printing inks are formed from the alcohol-soluble colour salts by mixing them with oxygen-containing polar organic solvents such as alcohols, ethers, ketones, esters or halogenated hydrocarbons together with conventional additives such as wetting-agents and polyethylene wax anti-blocking agent. An Example (43) is given in which a colour salt is mixed with shellac, dibutyl phthalate and ethanol.
Patent ES-336689-A1 (ES)
Title: Adsorbent for Treating Fermented or Fermentable Liquids
IPC: C12H1/048
Filed: 1967-02-10
Abstract: An absorbent, prepared from expanded montmorillonite clay (see the C1 Division Abridgment) is used in the treatment of beer as a protein content stabilizing control and to reduce the low temperature turbidity of the beer.
Patent ES-344133-A1 (ES)
Title: Sonic aerosol filtering devices
IPC: B01D49/00
Filed: 1967-08-14
Abstract: A gas filter comprises a plurality of inward flow filter sleeves or bags 20 which are cleaned by a combination of reverse flow and sonic vibration. As shown, clean cas outlet manifolds 30, one above each row of bags, contain steam or gas-opearted horns or whistles 36, 27 which generate standing waves, the steam or gas being directed into bags 20 from the horns or whistles, supplemented if necessary by more gas from valved inlet 21. The wave length is such that antinodes occur opposite the filter sleeves 20, whose lower ends are closed by plates and whose lengths are such that standing waves are established therein. Dust removed from the bags is removed from the filter housing by screw conveyor 26. Sleeves 20 are clamped around spigots 33 and end plates 22. When closed bags are used, these imay have lower end rings for suspending weights. Plate valves 38, 39 facilitate whistle replacement. In Fig. 3 (not shown), the manifolds are all connected through valves to a common sound duct (50) and to a filtered gas outlet duct (60), and the valves are operated in sequence to direct sonic waves into one manifold (A, B, C or D) at a time. The spacing of openings (73 . . 76) into the manifolds and the manifold lengths, up to valves (63. .66) which serve as sound reflectors, are arranged as whole numbers of wavelengths. Both embodiments illustrate two sound sources, at opposite ends of their chambers 30, (50), but a single source at one end could be used. The other end would then ibe closed by a paraboloidal reflector, as may the lower ends of sleeves 20.