baber/WOPTO huggingface dataset:
Patent WO-2023244498-A1 (WO)
Inventor: ESSEGHIR MOHAMED
IPC: B29B7/88
Filed: 2023-06-09
Abstract: L'invention concerne une méthode de fabrication rapide d'une composition de composé réticulable à ultra-haute température, faible échauffement comprenant un mélange homogène d'une polyoléfine thermoplastique, d'un antioxydant et d'additifs curatifs comprenant un ou plusieurs peroxydes organiques et un ou plusieurs co-agents de réticulation multialcényle. La méthode évite des tours de trempage et des temps de trempage longs, tout en rendant une composition de composé homogène entièrement réticulable avec une réticulation prématurée minimale ou nulle de la ou des polyoléfines thermoplastiques.
Patent WO-2023249970-A1 (WO)
Title: Composés bifonctionnels contenant des dérivés de pyrimidine pour dégrader la kinase 2 dépendante des cyclines par l'intermédiaire d'une voie ubiquitine-protéasome
Inventor: LOU YAN
IPC: C07D239/42
Filed: 2023-06-20
Abstract: La présente invention concerne certains composés bifonctionnels contenant des dérivés de pyrimidine qui provoquent la dégradation de la kinase 2 dépendante des cyclines (CDK2) par l'intermédiaire de la voie ubiquitine-protéasome et sont par conséquent utiles pour le traitement de maladies médiées par CDK2. L'invention concerne également des compositions pharmaceutiques contenant de tels composés et des procédés de préparation de tels composés.
Patent WO-2023168136-A1 (WO)
Inventor: BALDE ANSH ABHAY
IPC: H04N7/14
Filed: 2023-01-03
Abstract: L'invention concerne des systèmes, des procédés et des supports lisibles par ordinateur pour les appels vidéo. Un exemple de procédé peut consister à établir un appel vidéo entre un premier dispositif et un second dispositif ; à afficher un aperçu d'un premier flux de caméra et d'un second flux de caméra, le premier flux de caméra comprenant une première image vidéo capturée par un premier dispositif de capture d'image du premier dispositif et une seconde image vidéo capturée par un second dispositif de capture d'image du premier dispositif, la première image vidéo et la seconde image vidéo étant visuellement séparées dans l'aperçu ; à recevoir une sélection d'un ensemble de sujets représentés dans l'aperçu ; et à générer, sur la base du premier flux de caméra et du second flux de caméra, une seule image représentant l'ensemble de sujets.
Patent WO-2023150708-A1 (WO)
Title: Procédé de séparation d'adn génomique pour l'amplification de cibles d'acide nucléique court
Inventor: ZHANG HONGHUA
IPC: C12Q1/6806
Filed: 2023-02-03
Abstract: L'invention concerne des procédés, des compositions et des kits destinés à être utilisés dans la détection d'une séquence d'acide nucléique cible dans un échantillon. L'invention concerne également des compositions acides pour séparer l'ADNdb. Dans certains modes de réalisation, les compositions acides comprennent un sel monovalent et/ou un sel divalent, un ou plusieurs tensioactifs, et un agent acide. Dans certains modes de réalisation, le pH de la composition acide est inférieur à 4. L'invention concerne également des compositions de réactifs comprenant un agent tampon et un ou plusieurs agents d'amplification.
Patent WO-2023230516-A1 (WO)
Title: Attache covalente de la protéine portail dans des nanopores à l'état solide
Inventor: WANUNU MENI
IPC: G01N33/543
Filed: 2023-05-24
Abstract: L'invention concerne des capteurs et des procédés associés de fabrication et d'utilisation de capteurs. Le capteur comprend une protéine portail, telle que G20c dérivée du bactériophage Thermits thermophilus, liée de manière covalente à une surface thiol-silane d'une membrane à l'état solide comportant un ou plusieurs nanopores. Les capteurs peuvent être utilisés pour le séquençage de protéines et/ou de nucléotides ainsi que pour la détection de petites molécules.
Patent WO-2023235763-A1 (WO)
Title: Procédé de réduction de tts associé à un vecteur adénoviral
Inventor: ABBINK PETER
IPC: A61K35/761
Filed: 2023-05-31
Abstract: La présente invention concerne des procédés de réduction du risque de thrombose avec le syndrome de thrombose-thrombocytopénie (TTS) associé à une thérapie par vecteur adénoviral.
Patent WO-2023245146-A1 (WO)
Inventor: SCHUELKE AARON MARK
IPC: G02B27/01
Filed: 2023-06-15
Abstract: La présente invention concerne un dispositif de lunetterie destiné à être porté sur une tête d'un utilisateur pour présenter un contenu virtuel à un utilisateur, lequel dispositif de lunetterie comprend une structure de monture ayant une partie avant de monture, et un ensemble optique ayant une première rigidité. L'ensemble optique a un châssis et une pluralité de composants optiques fixés au châssis. Le dispositif de lunetterie comprend en outre une pluralité de montures couplant mécaniquement le châssis de l'ensemble optique à la partie avant de monture, au moins l'une de la pluralité de montures ayant une seconde rigidité inférieure à la première rigidité, de telle sorte que la ou les montures sont configurées pour empêcher au moins une partie d'une première charge de déformation statique appliquée à la partie avant de monture d'être communiquée mécaniquement à l'ensemble optique.
Patent WO-2024006931-A1 (WO)
Inventor: PERALTA EIGEN
IPC: C12N5/078
Filed: 2023-06-29
Abstract: La présente invention concerne des procédés et des compositions permettant d'obtenir des cellules effectrices dérivées fonctionnellement améliorées, obtenues à partir de la différenciation dirigée de iPSC modifiées par génie génétique. Les cellules dérivées de la présente invention comportent une édition génomique stable et fonctionnelle permettant d'obtenir des effets thérapeutiques améliorés ou accrus. L'invention concerne également des compositions thérapeutiques et leur utilisation faisant appel aux cellules effectrices dérivées fonctionnellement améliorées seules ou avec des anticorps ou des inhibiteurs de points de contrôle dans des polythérapies.
Patent WO-2024026425-A1 (WO)
Title: Polymer coated lead-free projectile and method of making the same
Inventor: GEIST KEVIN
IPC: F42B12/74
Filed: 2023-07-27
Abstract: A method of making a polymer-coated, lead-free projectile. In an embodiment, the method comprises compressing a lead-free metal powder to form a green core, heating the green core to bond the lead-free metal powder to form a metal compact of desired strength and placing the metal compact into fluidized bed of polymer to bond polymer to the metal compact to form a polymer coated compact. A polymer-coated, lead-free projectile made according to the described method, and a loaded round comprising the polymer-coated, lead-free projectile are also disclosed.
Patent WO-2020160568-A1 (WO)
Inventor: LAI NAM HAI
IPC: A61K31/05
Filed: 2019-09-10
Abstract: La présente invention concerne un procédé de production d'une microémulsion de nano-CBD, qui consiste : (I) à préparer une phase de dispersion en dissolvant du CBD dans un solvant à base d'éthanol, le rapport entre la masse de CBD et le volume de solvant à base d'éthanol étant de 8/10, à une vitesse comprise entre 300 et 500 rpm, en chauffant à une température comprise entre 40 et 60 °C, pendant 4 à 8 heures; (ii) à préparer un support en chauffant un PEG (polyéthylène glycol) liquide représentant de 40 à 60 % en masse du mélange de PEG et d'eau, à une température comprise entre 60 et 80 °C, en agitant afin d'obtenir un mélange homogène; (iii) à ajouter le support à la phase de dispersion dans un rapport en masse de 40/60, à continuer à chauffer la phase de dispersion à une température comprise entre 40 et 60 °C, et à mélanger à une vitesse comprise entre 400 et 800 rpm; (iv) à émulsifier de la manière suivante : lorsque la température atteint 100 °C, à ajouter de l'ACRYSOL K-140 au mélange du support et de la phase de dispersion obtenue à l'étape (iii) dans un rapport en masse de 40 / 60, à continuer à mélanger à une vitesse comprise entre 500 et 700 rpm, à une température d'environ 100 °C, sous vide, la température de réaction étant maintenue à 100 °C pendant 3 à 5 heures en contrôlant la qualité des produits résultants jusqu'à transparence, puis la réaction étant stoppée et la température abaissée lentement jusqu'à ce qu'elle se situe dans une plage comprise entre 40 à 60 °C; à émulsionner l'ensemble du mélange pendant 30 minutes, à une vitesse comprise entre 400 et 800 rpm. (v) à filtrer les produits en les injectant à travers des nanofiltres avant le remplissage-conditionnement.
Patent DK-202070680-A1 (DK)
Title: Water mixing detection device, water mixing detection program, water mixing detection method, and water mixing detection system
Inventor: Hidemitsu Harada
IPC: G01N33/30
Filed: 2020-10-07
Abstract: It is an object of the present invention to provide a water mixing detection device capable of determining whether or not the water content in the oil is actually normal under the environmental condition. The above object is solved by a water mixing detection device for detecting water mixed into oil, the water mixing detection device including: a predictive data calculator that calculates, based on a correlation between environmental data of oil and/or data regarding a surrounding environment of the oil and data regarding a water content in the oil, predictive data regarding the water content in the oil from actually measured environmental data of the oil and/or data regarding the surrounding environment of the oil; a measured data acquirer that acquires measured data regarding the water content in the oil; a condition determiner that determines whether or not a relation between the measured data and the predictive data satisfies a prescribed condition by comparing the acquired measured data and the calculated predictive data; and an information out-putter that outputs information indicating that the prescribed condition is satisfied, when it is determined that the relation between the measured data and the predictive data satisfies the prescribed condition.
Patent PH-12013500597-A1 (PH)
Title: Polarizing photochromic devices and methods of making the same
Inventor: ANIL KUMAR
IPC: G02B5/30
Filed: 2013-03-26
Abstract: Various embodiments disclosed herein relate to optical elements comprising an at least partial coating having a first state and a second state connected to at least a portion of a substrate, the at least partial coating being adapted to switch from the first state to the second state in response to at least actinic radiation, to revert back to the first state in response to thermal energy, and to linearly polarize at least transmitted radiation in at least one of the first state and the second state. Other embodiments relate to optical elements comprising a substrate and at least one at least partially aligned photochromic-dichroic compound connected to at least a portion of the substrate and having an average absorption ratio greater than 2.3 in the activated state as determined according to CELL METHOD. Still other embodiments relate to security devices, liquid crystal cells and methods of making the same.
Patent PH-12014501079-A1 (PH)
Title: 4 - pregenen- 11ss - 17 - 21 -triol-3, 20 -dione derivatives for the treatment of ocular conditions
Inventor: EDELMAN JEFFREY L
IPC: A61P27/02
Filed: 2014-05-09
Abstract: The present invention relates to novel 4-pregenen-11-17-21-triol-3,20-dione derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals, as modulators of glucocorticoid or mineralocorticoid receptors. The invention relates specifically to the use of these compounds and their pharmaceutical compositions to treat disorders associated with glucocorticoid or mineralocorticoid receptor modulation.
Patent PH-12015501071-A1 (PH)
Title: Combination therapy of anti-her3 antibodies
Inventor: FRIEDER BAUSS
IPC: C07K16/28
Filed: 2015-05-14
Abstract: The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.
Patent PH-12015502567-A1 (PH)
Title: Fueling apparatus
Inventor: AKIFUMI KANAMORI
IPC: B67D7/22
Filed: 2015-11-12
Abstract: [OBJECT] To provide a fueling apparatus that can improve operability especially for fueling to bikes and prevent injustice fueling by a person who performs fueling. [MEANS OF REALIZING THE OBJECT] A fueling nozzle via a flowmeter 17 from a fueling pump 22, a fueling control device 9 for controlling the fueling mechanism, a plurality of switch means 6, 7 for respectively performing a fuel setting to control the fueling mechanism, an information display portion 10 for displaying a fueling data, a nozzle hook 19 for hanging the fueling nozzle, and a nozzle switch 20 for maintaining an off state when the fueling nozzle is hanged on the nozzle hook and for maintaining an on state when the fueling nozzle is detached from the nozzle hook, wherein after fueling wih the fueling mechanism, turning one of the plurality of switch means on under a condition that the nozzle switch is on returns a display of the fueling date in the information display portion to zero and performs fueling by the fueling mechanism again.
Patent PH-12016000411-A1 (PH)
Title: Custom cremation urn
Inventor: DEL ROSARIO CIPRIANO A
IPC: G03H1/22
Filed: 2016-11-18
Abstract: The present invention relates to a custom cremation urn having an urn body having a configuration that is a replica of the deceased person in which the ashes is contained therein, and information system integrated to said urn which includes a micro-processing unit and a holographic projector.
Patent PH-12016500292-A1 (PH)
Title: Processes for preparing color stable manganese-doped phosphors
Inventor: EDWARD MURPHY JAMES
IPC: H01L33/50
Filed: 2016-02-11
Abstract: Low-HF or HF-free processes for improving color stability of a Mn+4 doped phosphor of formula (I) include contacting the phosphor of formula (I) with a solution that contains hexafluorosilicic acid, and isolating a treated phosphor of formula (I) having improved color stability relative to an untreated phosphor of formula (I): Ax [MFy]:Mn+4 wherein A is Li, Na, K, Rb, Cs, R4 or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; R is H, lower alkyl, or a combination thereof; x is the absolute value of the charge of the [MFy] ion; and y is 5, 6 or 7.
Patent PH-12016500743-A1 (PH)
Title: Treatment using bruton`s tyrosine kinase inhibitors and immunotherapy
Inventor: RONALD LEVY
IPC: A61P35/00
Filed: 2016-04-20
Abstract: Combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., l-((R)-3-(4-amino-3-(4- phenoxyphenyl)- 1 H-pyrazolo [3,4-d]pyrimidin- 1 -yl)piperidin- 1 -yl)prop-2-en- 1 -one, with immunotherapy are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1- ((R)-3-(4-amino-3-(4-phenoxyphenyl)-lH-pyrazolo[3,4-d]pyrimidin-l-yl)piperidin-l-yl)prop-2- en-l-one, and an immune checkpoint inhibitor.
Patent PH-12016502168-A1 (PH)
Title: Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
Inventor: CHRISTOPHE BARLAAM BERNARD
IPC: C07D471/04
Filed: 2016-11-02
Abstract: The specification generally relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, where Q, R1, R2, R3, R4 and R5 have any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent ATM kinase mediated disease, including cancer. The specification further relates to crystalline forms of compounds of imidazo[4,5- c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds and salts; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; intermediates useful in the manufacture of such compounds and salts; and to methods of treating ATM kinase mediated disease, including cancer, using such compounds and salts.
Patent PH-12017500104-A1 (PH)
Title: Washing machine
Inventor: AKAGI TAKAYOSHI
IPC: D06F39/00
Filed: 2017-01-17
Abstract: A washing machine is provided with a water tank for holding washing solution, a rotating drum enclosed in the water tank and holding the clothes, a housing tank equipped with the water tank and the rotating drum, and a suds-generating unit for generating suds and supplying the generated suds to the housing tank. Furthermore, the suds-generating unit is provided with a suds-generating chamber for retaining the washing solution supplied from a circulation pump. The washing solution supplied from the circulation pump collides with the liquid surface of the washing solution retained inside the suds-generating chamber. As a result, a washing machine with a simple configuration and capable of washing clothes efficiently with suds is provided.
Patent PH-12017502140-A1 (PH)
Title: Clothes dryer
Inventor: NAKAI KOUJI
IPC: D06F58/22
Filed: 2017-11-24
Abstract: This clothes dryer comprises: an air inlet path (25) through which air for drying is delivered to a rotating drum from an air inlet (23); and an air outlet path (26) through which air for drying which has dried clothes in the rotating drum is delivered to an air outlet (24). The clothes dryer is provided with a first adjoining surface and a second adjoining surface (38b) which are heat exchanging parts that allow the air for drying passing through the air inlet path (25) and the air outlet path (26) to heat exchange with each other.
Patent PH-12018500998-A1 (PH)
Title: Improvements in or relating to a closure for a container neck
Inventor: MCPHERSON ALEXANDER DONALD MEIKLEM
IPC: B65D55/02
Filed: 2018-05-08
Abstract: A closure (101) for a container neck comprises a first portion (102) comprising a body (104) for fixing to the container neck and a second portion (103) comprising a cap (105) releasably engageable with the body (104). The closure (101) comprises a seal support portion (107) formed from a first plastics material and a seal (106) formed from a second plastics material that is more compliant than the first plastics material, the seal (106) formed integrally with the seal support portion(107). A closure (101) with a bi-injection moulded seal. A method of forming the closure (101) comprising the step of bi-injection moulding the seal support portion (107) and the seal(106). A container comprising a container neck provided with the closure (101).
Patent PH-12018501010-A1 (PH)
Title: Aerosol generating article with ventilation zone
Inventor: BATISTA RUI NUNO
IPC: A24D1/22
Filed: 2018-05-08
Abstract: There is provided an aerosol generating article (100) comprising a combustible heat source(102), an aerosol forming substrate (104) downstream of the combustible heat source, and a wrapper (126) circumscribing at least a rear portion of the combustible heat source and at least a front portion of the aerosol forming substrate. A plurality of weakness formations (150) are provided on a region of the wrapper overlying the combustible heat source. The wrapper is rupturable during use at the plurality of weakness formations to form a ventilation zone comprising a plurality of apertures extending through the wrapper. The weakness formations may be arranged such that the wrapper ruptures at the weakness formations under the pressure generated by combustion gases from the combustible heat source during use.
Patent PH-12018502387-A1 (PH)
Title: Adeno-associated virus variant capsids and methods of use thereof
Inventor: KIRN DAVID H
IPC: C12Q1/70
Filed: 2018-11-12
Abstract: Provided herein are variant adeno-assoeiated virus (AAV) capsid proteins having one or more modifications in amino acid sequence relative to a parental AAV capsid protein, which, when present in an AAV virion, confer increased infectivity of one or more types of retinal cells as compared to the infectivity of the retinal cells by an AA V virion comprising the unmodified parental AAV capsid protein. Also provided are recombinant AAV virions and pharmaceutical compositions thereof comprising a variant AAV capsid protein as described herein, methods of making these rAAV capsid proteins and virions, and methods for using these rAAV capsid proteins and virions in research and in clinical practice, for example in, e.g., the delivery of nucleic acid sequences to one or more cells of the retina for the treatment of retinal disorders and diseases.
Patent PH-12019000048-A1 (PH)
Title: Automated submersible rescue and garbage collecting apparatus
Inventor: ARANDA CHRISTOPER R
IPC: E04H4/16
Filed: 2019-01-31
Abstract: Now a day, we faced a lot of challenges in our daily lives, not only on ourselves but also the marine life too. We knew that one of the challenges is the hazardous materials that the ocean acquired due to lack of human discipline. We are talking about the plastics, tin cans and other hazardous waste that can harm and risk marine ecology. We develop a mechanical marine life prototype robot that can collect rubbish on the ocean and sea bed, it also has a sensor that can detect and recognize anything in its pathway, and a mouth that has the ability to intake rubbish and a body that can grind all rubbish into tiny pieces that it swallows. It also have solar panels in the body to be able to produce its own source of energy, a global positioning system (GPS) to monitor its location and a hands that can lay a device to a person or things etc., to detect when search and rescue operation needed. We want to preserve and save marine life and save the ocean too for our future that is why we made this eco-friendly submersible mechanical apparatus.
Patent PH-12019000116-A1 (PH)
Title: Semi pre-fabricated wall for construction
Inventor: KITTAYAPONG RUNGRITH
IPC: E04C2/00
Filed: 2019-03-05
Abstract: The semi pre-fabricated wall for construction consists of partition wall which is a concrete wall panel, or a mixed concrete wall panel, or autoclaved aerated concrete wall panel, or a wall panel made from preferred material casted into a lengthy flat panel with smooth or rough front or back surfaces. Meanwhile, the surface of the front side of the partition wall panel will be a rack of grate reaching out together along with casting of partition wall formation. It will be assembled with another partition wall panel to make a partition wall panel, or a cornered partition wall panel section, or a U-shape partition wall panel section, or a support beam, or a reinforced column. Meanwhile, the left edge of the partition wall panel will be aligned with a groove connecting the left- hand side or a tongue sticking out for inserting and connecting with the right groove, or the curved-in groove of another partition wall panel, whilst joining the sides of each preferred partition wall panel together.
Patent PH-12019050104-A1 (PH)
Title: Use of edaravone for treating acute ischemic stroke
Inventor: NAVARRO Jose C
IPC: A61K39/00
Filed: 2019-07-12
Abstract: Edaravone for use in treating acute ischemic stroke in human wherein with the dose of about 30 mg/ml dissolved in 100ml normal saline as intravenous infusion for 60 minutes . @X daily for 14 days. For patients: a) 18-70 years old and with acute ischemic stroke within 24 hours demonstrated by CT-Scan, b) Focal deficit measurable by NIH Stroke Scale, c) Patients with a level of conscious between 0 (alert) and 3 (unable to recall the name and date of birth) according to the Japan Coma Scale, d) Patients with motor dysfunction of upper and/or lower.
Patent PH-12019500106-A1 (PH)
Title: Nozzle hook and fueling apparatus
Inventor: KANO SHINGO
IPC: B67D7/12
Filed: 2019-01-15
Abstract: To provide a fueling apparatus nozzle hook, the nozzle switch of which always works accurately. [Solution]  In this fueling apparatus nozzle hook (1) that has a main nozzle hook body (2) in which the spout of a fueling nozzle is held, a receiving section (3) for holding the lever guard of the fueling nozzle, and a switch (4, 4-2, 4-3): the switch has a detected part (5) that emits lines of magnetic force or light, a detecting part (6) for detecting the lines of magnetic force or light emitted from the detected part, and an operation piece (7, 7-2, 7-3); and the operation piece is capable of moving between a position that blocks the lines of magnetic force or light emitted from the detected part from reaching the detecting part and a position that does not block same.