baber/WOPTO huggingface dataset:
Patent JP-4219980-B2 (JP)
IPC: C08B3/04
Filed: 1996-06-28
Granted: 2009-02-04
Abstract: PCT No. PCT/EP96/02827 Sec. 371 Date Mar. 17, 1998 Sec. 102(e) Date Mar. 17, 1998 PCT Filed Jun. 28, 1996 PCT Pub. No. WO97/02292 PCT Pub. Date Jan. 23, 1997Process for preparing a solution of cellulose formate from cellulose plates, in particular high-density plates, without prior mechanical destruction of these plates. The plates are dissolved directly, by means of an impregnating step of the whole plates in a base liquid of formic acid, followed by an operation of kneading of the plates thus impregnated in contact with both formic acid and phosphoric acid. The process is preferably carried out in order to prepare ready-for-spinning solutions with, in particular, if necessary, an intermediate operation of adjustment of the final composition. Solutions prepared using such a process. Preparation of objects made of cellulose, starting with these solutions, in particular fibers or films. Assemblies of such fibers or films. Articles reinforced with such fibers or films or assemblies, these reinforced articles being especially tires.
Patent JP-3839843-B2 (JP)
IPC: A61K48/00
Filed: 1995-07-18
Granted: 2006-11-01
Abstract: The invention provides a method of preventing or reducing the severity of a cancer in a subject by stimulating the subject's immune response against the cancer. The invention provides, for example, a method of stimulating an immune response in a subject by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to reduce or inhibit the expression of one or more immunosuppressive agents. The invention also provides a method of preventing or reducing the severity of cancer in a subject by stimulating the subject's immune response against the cancer by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to prevent the expression of an immunosuppressive agents and, in combination with the genetically modified tumor cells, an immunostimulatory agent. The invention further provides compositions useful for practicing the claimed methods.
Patent JP-3343358-B2 (JP)
IPC: A23L33/12
Filed: 1997-06-06
Granted: 2002-11-11
Abstract: There is provided a process for preparing lipids containing docosahexaenoic acid and/or docosapentaenoic acid, comprising: cultivating in a medium a microorganism of genus  Ulkenia  having the ability to produce lipids containing docosahexaenoic acid and/or docosapentaenoic acid, and recovering said lipids from a culture; wherein globose or oval cells and biflagellate zoospores are observed when the microorganism is cultured in a KMV liquid medium at 20°C in the dark, whereas a network of ectoplasm filaments is not observed.
Patent JP-3415154-B2 (JP)
IPC: A23J3/34
Filed: 1993-11-10
Granted: 2003-06-09
Abstract: PCT No. PCT/EP93/03151 Sec. 371 Date Jul. 19, 1995 Sec. 102(e) Date Jul. 19, 1995 PCT Filed Nov. 10, 1993 PCT Pub. No. WO94/10856 PCT Pub. Date May 26, 1994Described is the chemical hydrolysis of partial hydrolysates obtained by the enzymatic decomposition, in aqueous conditions in the presence of alkaline-earth oxides or hydroxides, of protein-containing raw materials containing chromium. This enables protein hydrolysates with a particularly low chromium content to be obtained which are stable to turbidity during storage. The chemical hydrolysis must be carried out in the presence of compounds selected from the alkaline-earth oxides and hydroxides, and within the critical pH range of 11 to 13.
Patent JP-4064453-B2 (JP)
IPC: A61K9/14
Filed: 1995-10-13
Granted: 2008-03-19
Abstract: A pharmaceutical formulation comprising a growth hormone and valine as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
Patent JP-H0692932-B2 (JP)
IPC: G01N35/04
Filed: 1991-08-16
Abstract: PCT No. PCT/EP91/01564 Sec. 371 Date Aug. 14, 1992 Sec. 102(e) Date Aug. 14, 1992 PCT Filed Aug. 16, 1991 PCT Pub. No. WO92/11527 PCT Pub. Date Jul. 9, 1992.In order to ensure that, in a cuvette for holding substances to be analyzed preferably by optical means, more particularly for the analysis of chromogenic substances, solutions and substrates, having a measuring section that is closed at the bottom for accommodating the substance, that, when providing optimal marginal conditions for the measurement, the handling of the cuvette prior to, during and subsequent to the termination of the measurement operations, can take place with a minimal risk of contamination, it is proposed that, to the measuring section, a section extending the cuvette adjoins, with the aid of which a preferably detachable plug-in connection can be established to the measuring section of a further cuvette.
Patent JP-2665399-B2 (JP)
IPC: A01N1/02
Filed: 1993-03-04
Granted: 1997-10-22
Abstract: An implantable medical device having long lasting resistance to staphylococcal biofilm colonization is provided. Implantable medical devices such as catheters, shunts, prosthesis, pacemakers, etc. are susceptible to colonization by biofilm adherent microorganisms, especially staphylococci. While systemic staphylococcal infections are effectively treated by many antibiotics, vancomycin being the antibiotic of choice, this same bacteria when encased in biofilm adhering to indwelling medical devices is generally resistant to antibiotic treatment. By the present invention, the combination of rifampin and minocycline or the combination of rifampin and novobiocin when coated on the surfaces of implantable medical devices unexpectedly provides superior antibacterial activity against staphylococcal biofilm colonization on the coated surface of indwelling medical devices.
Patent JP-3623801-B2 (JP)
IPC: A23C3/037
Filed: 1995-11-14
Granted: 2005-02-23
Abstract: PCT No. PCT/DK95/00453 Sec. 371 Date May 19, 1997 Sec. 102(e) Date May 19, 1997 PCT Filed Nov. 14, 1995 PCT Pub. No. WO96/15677 PCT Pub. Date May 30, 1996A plant for continuously sterilizing fluids, such as milk and cream comprises a sterilizing device (2) in which the fluid is sterilized while steam is fed thereto, and a vacuum chamber (1) for removal of the water from the fluid and from which the fluid is extracted by means of a pump (8). The vacuum chamber (1) is accommodated before the sterilizing device (2) when seen in the flow direction of the fluid, said vacuum chamber (1) being connection to said sterilizing device (2) through a first heat exchanger (11) for heating the fluid before it enters said sterilizing device (2).
Patent JP-4184436-B2 (JP)
IPC: H04N7/173
Filed: 1997-10-16
Granted: 2008-11-19
Abstract: An interactive television system in which URL representing an Internet web site is encoded in a television signal. The user may link to the web site by selecting an icon (95) displayed on the television screen.
Patent JP-2846961-B2 (JP)
IPC: C12R1/19
Filed: 1995-03-13
Granted: 1999-01-13
Abstract: PCT No. PCT/EP95/00926 Sec. 371 Date Sep. 13, 1996 Sec. 102(e) Date Sep. 13, 1996 PCT Filed Mar. 13, 1995 PCT Pub. No. WO95/25168 PCT Pub. Date Sep. 21, 1995Process for purifying serine proteases from a protein mixture by binding the serine protease to an immobilized polypeptide with the activity of an inhibitor DE-3 from Erythrina caffra, removing unbound components from the protein mixture, detaching the serine protease from the inhibitor and separating the immobilized inhibitor from the soluble serine protease and isolating serine protease which is characterized in that a polypeptide is used as the polypeptide which is the product of a prokaryotic or eukaryotic expression of an exogenous nucleic acid. This inhibitor is distinguished by an improved specific activity and is particularly suitable for the purification of plasminogen activators such as tissue plasminogen activators (t-PA and derivatives).
Patent JP-3578459-B2 (JP)
IPC: A61M25/06
Filed: 1995-04-20
Granted: 2004-10-20
Abstract: This invention includes protective devices for protecting against needle-stick injury by a medical catheter or needle. More particularly, the invention is concerned with guards for use with wingless needle assemblies of the type used by blood banks. However, it is also applicable to winged needle assemblies used for other medical purposes, such as the intravenous (IV) infusion of fluids. The needle or catheter assemblies of the type concerned here, comprise a needle, a needle mount or block, and a flexible tube, which are connected at one end to the needle via the needle mount and at the other end to a blood collection bag or to an IV fluid source. A winged catheter or needle assembly is one having a pair of flexible wing-like protrusions extending laterally from its mount, the wings being taped to the user's skin to keep the needle in place over the long periods of time often needed for IV infusions.
Patent JP-4269076-B2 (JP)
IPC: C10M133/06
Filed: 1997-05-20
Granted: 2009-05-27
Abstract: PCT No. PCT/EP97/02571 Sec. 371 Date Nov. 5, 1998 Sec. 102(e) Date Nov. 5, 1998 PCT Filed May 20, 1997 PCT Pub. No. WO97/44366 PCT Pub. Date Nov. 27, 1997Polyalkeneamines of the formula (I) where R1, R2, R3, R4, R5 and R6 may have different meanings, are prepared by a process in which a polyalkene epoxide is reacted with an amine and the amino alcohol is dehydrated and reduced to give the compound of the formula (I).
Patent JP-4080548-B2 (JP)
IPC: C07B61/00
Filed: 1998-03-26
Granted: 2008-04-23
Abstract: The invention is an improved method for the preparation of tertiary phosphines by way of cross-coupling of aryl, alkenyl, cycloalkenyl or aralkyl halides or aryl, alkenyl, cycloalkenyl or aralkyl sulfonate esters with chlorophosphines in the presence of a catalyst and a reductant. The general reaction scheme is shown below: wherein R1 is aryl, alkenyl, cycloalkenyl or aralkyl, any of which may be substituted by one or more of the following: alkyl, aryl, aralkyl, alkoxy, alkanoyl, chloro, fluoro, alkoxycarbonyl, cyano, trifluoromethyl, cycloalkyl, or CONR4R5 wherein R4 and R5 are independently hydrogen, alkyl, aryl or aralkyl; R2 and R3 are independently aryl, alkyl, aralkyl, any of which may be substituted by one or more of the following: alkyl, aryl, aralkyl, alkoxy, alkanoyl, chloro, fluoro, alkoxycarbonyl, cyano, trifluoromethyl, cycloalkyl or CONR4R5 wherein R4 and R5 are independently hydrogen, alkyl, aryl or aralkyl; and n is 2 where R1 is a difunctional moiety and 1 for any other R1; and X is Cl, Br, I, or OSO2Y; wherein Y is alkyl, trihalomethyl, phenyl, halophenyl, or alkylphenyl.
Patent JP-4865115-B2 (JP)
IPC: C07C303/36
Filed: 1998-05-15
Granted: 2012-02-01
Abstract: The invention concerns a method of sulphonation characterised in that it consists in contacting a nucleophile whose nucleophilic atom is a nitrogen atom with a reagent comprising by successive or simultaneous addition: a heavy sulphonyl halide (i.e. whose atomic number is not less than that of chlorine), advantageously suphonyl chloride; and an organic base both not capable of alkylation and lipid soluble; and the organic part of said sulphonyl is perfluorinated on the carbon carried by the sulphur. The invention is applicable to organic synthesis.
Patent MD-2705-B2 (MD)
Title: Process for obtaining bis(4-hydroxyaryl)alkanes from the adducts of bis(4-hydroxyaryl)alkanes and aromatic hydroxyl compounds
Inventor: KüHLING STEFFEN
IPC: C07C37/00
Filed: 1999-10-05
Abstract: The invention relates to a process for obtaining bis(4-hydroxyaryl)alkanes.The process for obtaining bis(4-hydroxyaryl)alkanes from the adducts of bis(4-hydroxyaryl)alkanes and aromatic hydroxyl compounds provides for the following phases:a) through the melt of an adduct of bis(4-hydroxyaryl)alkane and of an aromatic hydroxyl compound at the temperature of 150…230°C there is passed an inert gas, at the same time the inert gas flow eliminates the aromatic hydroxyl compound from the melt;b) the aromatic hydroxyl compound is removed from the inert gas flow by condensation;c) the inert gas flow is purified, subjected to compression and reintroduced into the phase (a).The bis(4-hydroxyaryl)alkanes, obtained by the claimed process, are characterized by a minimum degree of colouring, as well as by high purity, due to the reduction of content of the aromatic hydroxyl compounds and of the splitting products.
Patent ES-2193895-B2 (ES)
Title: Oligomero aromatico y su utilizacion.
Inventor: SENZAKI TOSHIHIDE
IPC: C08G14/04
Filed: 2001-03-08
Granted: 2004-08-01
Abstract: Esta invención se refiere a un oligómero aromático representado por la siguiente fórmula (1) (A-F)n-A donde A es una unidad que comprende (a) 30-90% en peso de un compuesto aromático bicíclico o tricíclico y (b) 10-70% en peso de un compuesto fenol, F es metileno o una mezcla de metileno y -CH2OCH2- y n es un número de 1 a 100. El oligómero aromático se obtiene por reacción de un compuesto aromático policíclico tal como naftaleno y benzotiofeno, un fenol y compuesto de formaldehido en presencia de un catalizadoar ácido. El oligómero aromático es inodoro y es útil para varias aplicaciones. En particular, cuando se incorpora a caucho o resina, el orligómero aromático puede actuar en forma excelente como substancia adherente en un amplio intervalo de temperaturas o actuar en forma excelente como agente de amortiguamiento de vibraciones.
Patent ES-2214160-B2 (ES)
Title: Articulacion perfeccionada para paneles de puertas y similares.
Inventor: RODRIGUEZ RIVAS VICTORINO
IPC: E06B7/36
Filed: 2004-04-16
Granted: 2005-03-01
Abstract: Articulación perfeccionada para paneles de puertas y similares, para la unión de paneles (3 y 4) formados por una estructura de chapas (5 y 6) con un relleno interior (7) de material ligero, incluyéndose en el interior de los mencionados paneles (3 y 4) un perfil de armadura (13) en forma de "U", el cual se dispone en la zona de sujeción de las bisagras (2) de la articulación, quedando con una de sus alas laterales apoyada contra la chapa estructural (5) del panel (3 ó 4) correspondiente, en donde queda sujeto por el material (7) de relleno.
Patent ES-2264637-B2 (ES)
Title: Maquina para la sujecion de ruedas en vehiculos.
Inventor: LAFFITTE FIGUERAS MARTI
IPC: B62D65/12
Filed: 2005-06-06
Granted: 2009-05-25
Abstract: Máquina para la sujeción de ruedas en
vehículos. 
     Permite llevar a cabo el montaje y sujeción de
las ruedas en los vehículos que acceden por la línea de montaje, de
forma  totalmente automatizada, sin intervención de operarios. 
     Consta de una bancada (1) de alimentación de las
ruedas, donde existe un elemento posicionador (23) que centra la 
rueda y la eleva para ser tomada por un brazo soporte (2) que la
traslada a un plato giratorio (3) vinculado a un  alimentador (4) de
tornillos que los coloca en la llanta con ayuda de un detector
óptico. En el brazo soporte (6) de una  bancada móvil (5) contigua a
I anterior, existe un atornillador múltiple (7) que se sitúa en los
tornillos, basculando después  el conjunto 90º para presentar la
rueda frente al cubo del vehículo e insertar finalmente la
rueda.
Patent ES-2370790-B2 (ES)
Title: Uso de oxalacetato en el tratamiento de isquemia.
Inventor: CASTILLO SANCHEZ JOSE
IPC: A61K9/08
Filed: 2010-05-25
Granted: 2012-10-18
Abstract: Uso de oxalacetato en el tratamiento de isquemia. La presente invención proporciona cantidades terapéuticamente efectivas para el tratamiento de trastornos asociados a elevados niveles de glutamato en el tejido cerebral, como por ejemplo, la isquemia cerebral. Además, las composiciones de la invención son adecuadas para la administración de tipo bolus.
Patent ES-2402457-B2 (ES)
Title: Procedimiento para el diagnóstico de derrame pleural maligno mediante la determinación de la concentración de calprotectina en líquido pleural.
Inventor: RODRIGUEZ BERROCAL FRANCISCO JAVIER
IPC: C07K14/47
Filed: 2011-10-19
Granted: 2014-01-20
Abstract: La presente invención se refiere al desarrollo y puesta a punto de un procedimiento utilizable para el diagnóstico del derrame pleural maligno, que permita distinguir a aquellos pacientes que presentan derrame pleural derivado de patologías de origen oncológico, de aquellos que sufren derrame pleural cuyo origen no es maligno.
Patent IE-S86788-B2 (IE)
Title: Inner receptacle apparatus for cut flowers
Inventor: KAREN ENGLISH
IPC: A47G7/00
Filed: 2016-07-26
Abstract: Provided is an inner receptacle apparatus for locating within a larger open-ended outer container, the inner receptacle apparatus: a receptacle body for receiving cut flowers; and one or more adjustable attachment members for locating the receptacle body within the outer container. <Figure 2>
Patent AU-2001247228-B2 (AU)
Title: Stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
Inventor: HAYDEN MICHAEL R
IPC: C12N5/10
Filed: 2001-02-23
Granted: 2007-01-18
Abstract: The use of screening assays based on the role of human stearoyl-CoA desaturase-1 ("hSCD1") in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
Patent AU-2001252198-B2 (AU)
Title: Device for cleaning teeth
Inventor: HILSCHER ALEXANDER
IPC: A46B5/00
Filed: 2001-03-14
Granted: 2006-10-19
Abstract: Hand piece (1) for an electrical teeth cleaning device comprises a coupling part for coupling a cleaning tool, especially a brush attachment, a drive mechanism (23) driving the cleaning tool, and a control device (27) controlling the drive mechanism. The control device has an operating lock device (100) released by a releasing element provided on the cleaning tool. Independent claims are also included for a cleaning tool and for an electrical teeth cleaning device. Preferred Features: The electronic operating lock device is released by the releasing element when the cleaning tool is coupled to the hand piece. The operating lock device is released on a signal from a coding device of the control element coding the release element.
Patent AU-2002231351-B2 (AU)
Title: Polymerization process
Inventor: SZUL JOHN FRANCIS
IPC: C08F2/01
Filed: 2001-11-07
Granted: 2005-11-10
Abstract: The present invention relates to a method to polymerize monomer comprising contacting one or more monomer(s) with a catalyst system in a gas phase reactor having a recycle system, for removing a recycle gas and unreacted monomer(s) from the reactor and returning the recycle gas and fresh monomer(s) to the reactor, and a plenum, the method comprising the steps of: (a) cooling the recycle gas to form a cooled recycle gas; (b) optionally combining the cooled recycle gas with additional recycle gas; and (c) injecting the cooled recycle gas into the gas phase reactor through the plenum.
Patent AU-2002329496-B2 (AU)
Title: Test strip assay system and method for the detection of specific nucleic acid sequences
Inventor: SOUFLA GIANNOULA
IPC: C12Q1/68
Filed: 2002-10-03
Granted: 2009-10-22
Abstract: Dipping test strip assay system, method for the construction of said test strip system, and method for the detection and/or determination of specific nucleic acid sequences by the use of assay hybridization protocols developed on said test strip system. Colloidal gold particles conjugated to oligonucleotides are dried on the strip, and the protein Streptavidin, as well as an oligonucleotide is immobilized at the membrane area of the strip. A specific nucleic acid sequence is detected when a visible signal indicative of the presence or absence of the analyte is developed at the region of the Streptavidin's immobilization, while the completion of the assay is confirmed by the development of a visible signal at the region of the oligonucleotide's immobilization. The dipping test strip assay system is useful for the rapid detection or determination of specific nucleic acid sequences in a sample, such as specific viral or bacterial nucleic acid sequences, as well as mutated DNA sequences of clinical significance, after the amplification of the specific nucleic sequence in the sample through a PCR reaction.
Patent AU-2003214044-B2 (AU)
Title: Anti-idiotypic antibody inducing HIV-1 neutralizing antibodies
Inventor: KUNERT RENATE
IPC: C07K16/42
Filed: 2003-01-17
Granted: 2008-06-26
Abstract: The invention relates to Ab2-type anti-idiotypic antibodies and fragments thereof which mimic HVI-1 epitopes that are otherwise cryptic to the immune system and which antibodies or fragments thereof are directed against potently neutralizing anti-HIV-1 antibodies. The invention further relates to a hybridoma cell line 3H6 expressing the anti-idiotypic antibody and to pharmaceutical compositions containing the antibody or fragment thereof. The invention also relates to HIV-1 neutralizing Ab3-type antibodies elicited upon administration of the Ab2-type anti-idiotypic antibody or fragment thereof and to pharmaceutical compositions containing them. The invention also relates to the use of the present antibodies or fragments thereof as screening tools or as diagnostic or therapeutic agents.
Patent AU-2003220493-B2 (AU)
Title: Secretion of proteins with multiple disulfide bonds in bacteria and uses thereof
Inventor: MASIP LLUIS
IPC: C12P21/02
Filed: 2003-03-24
Granted: 2008-06-05
Abstract: The invention provides methods for using the Twin Arginine Translocation pathway in bacteria to produce heterologous polypeptides that have multiple disulfide bonds. Methods of screening polypeptide libraries produced by secretion through the TAT pathway are also provided. The invention provides improved methods for production of heterologous polypeptides having at least one disulfide bond.
Patent AU-2003243975-B2 (AU)
Title: Aqueous fluorescent ink, recorded image using same, and judging method
Inventor: KOIKE SHOJI
IPC: B41J2/01
Filed: 2003-06-26
Granted: 2010-04-22
Abstract: The present invention provides a fluorescence ink having a high fluorescence intensity, and an ink jet recording method using the same. The ink contains a first fluorescent coloring material that emits fluorescence at a predetermined fluorescence wavelength to be used for measurement or determination with excitation at a predetermined excitation wavelength, a second fluorescent coloring material that emits fluorescence on excitation at the predetermined excitation wavelength, where the excitation spectrum of the first coloring material in the ink to obtain the fluorescence at the predetermined emission wavelength has a peak wavelength range next to the predetermined fluorescence wavelength, and the emission fluorescence spectrum of the second coloring material has an emission wavelength region substantially including at least the above peak wavelength range.