Patent GB-711710-A (GB)
Title: Germicidal fungicidal and similar compositions
IPC: A01N33/12
Filed: 1951-07-30
Abstract: A composition for use in germicidal detergents comprises (1) a quaternary ammonium germicide of the formula:- <FORM:0711710/III/1> wherein R1 is an alkyl group of 8 to 18 carbon atoms, Ar is an aryl nucleus, R1 is a methyl radical, m is from 0 to 4, Y is a halogen, n is from 0 to 8, R2, R3, and R4 are hydrocarbon substituents containing a total of no more than 12 carbon atoms, and X is a salt-forming anionic radical, and (2) a germicide promoter consisting of pine oil, octylphenylmonoethylene glycol ether, octylphenyldiethylene glycol ether or an alkyl aromatic hydrocarbon of 12 to 24 carbon atoms, the weight of hydrocarbon being from 2 to 8 per cent. of the whole composition, whilst the weight of pine oil, octylphenylmonoethylene glycol ether or octylphenyldiethylene glycol ether is from 10 to 60 per cent. of the whole composition. Quaternary ammonium compounds specified are dodecylbenzyl trimethyl ammonium chloride, chlorinated dodecylbenzyl trimethyl ammonium chloride (containing approximately 5 chlorine atoms), and dodecylmethylbenzyl trimethyl ammonium chloride.  Hydrocarbons specified are nonyl benzene, dodecyl benzene, pentadecyl benzene, octadecyl benzene and the corresponding alkyl toluenes of 12 to 24 carbon atoms. Hydrocarbons having an alkyl radical corresponding in structure to a polypropylene chain are preferred, particularly those containing a radical of from 12 to 15 carbon atoms.ALSO:A composition for the control of microorganisms including bacteria, fungi, algae and protozoa, said also to be applicable for use in germicidal detergents, ointments and cosmetics, comprises a quaternary ammonium germicide of the formula:-  <f/1> wherein R1 is an alkyl group of 8 to 18 carbon atoms, Ar is an aryl hydrocarbon nucleus, R1 is a methyl radical, m is from 0 to 4, Y is a halogen, n is from 0 to 8, R2, R3 and R4 are substituents of hydrocarbon structure containing a total of no more than 12 carbon atoms, and X is a saltforming anionic radical, and a quaternary germicide promoter consisting of pine oil, octylphenylmonoethylene glycol ether, octylphenyldiethylene glycol ether or an alkyl aromatic hydrocarbon oil of 12 to 24 carbon atoms, the weight of hydrocarbon oil being from 2 to 8 per cent of the whole composition, whilst the weight of pine oil, octylphenylmonoethylene glycol ether or octylphenyldiethylene glycol ether is from 10 to 60 per cent of the whole composition. Quaternary ammonium compounds specified are dodecylbenzyl trimethyl ammonium chloride, chlorinated dodecylbenzyl trimethyl ammonium chloride (containing approximately 5 chlorine atoms), and dodecyl methyl benzyl trimethyl ammonium chloride.  In the quaternary ammonium compounds, when the acyclic alkyl radicals are of a straight chain nature, those containing as few as 8 to 10 carbon atoms are found to be very satisfactory.  When branched-chain structures predominate the most satisfactory radicals are those containing from 10 to 18 carbon atoms. Hydrocarbon oils specified solvents e.g. water-soluble alcohols such are nonyl benzene, dodecyl benzene, pentadecyl benzene, octadecyl benzene and the corresponding alkyl toluenes of 12 to 24 carbon atoms. Hydrocarbon oils having an alkyl radical corresponding in structure to a polypropylene chain are preferred, with those containing from 12 to 15 carbon atoms being even more preferred.  With hydrocarbon oil promoters the proportion of promoter preferably ranges from 4 to 6 per cent, whilst for pine oil and the two ethers the preferred proportions are from 20 to 50 per cent by weight of the composition.