baber/WOPTO huggingface dataset:
Patent NZ-621520-A (NZ)
Title: Nuclear transport modulators and uses thereof
Inventor: SANDANAYAKA VINCENT P
IPC: C07D487/10
Filed: 2012-07-26
Abstract: Disclosed herein are nuclear transport modulators, e.g CRM1 inhibitors, represented by formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. Also disclosed is the synthesis and use of a compound of structural formula (I), or a pharmaceutically acceptable salt or composition thereof, in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity. Particular examples are when ring A is a triazole and ring B is di-triflurormethyl phenyl for example: (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3-((dimethylamino)methyl)-3-fluoroazetidin-1-yl)prop-2-en-1-one; (Z)-1-(3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acryloyl)-3-fluoroazetidine-3-carboxylic acid; and (Z)-1-(3-(aminomethyl)-3-fluoroazetidin-1-yl)-3-(3-(3,5-bis(trifluoromethyl) phenyl)-1H-1,2,4-triazol-1-yl)prop-2-en-1-one.
Patent NZ-710978-A (NZ)
Title: Automatic titrator
Inventor: BOLDUC JOHN WILHELM
IPC: G01N31/16
Filed: 2014-03-03
Abstract: A method for determining the amount of a desired component in a solution disclosed herein generally addresses the need to accurately determine the endpoint of a chemical reaction and to perform appropriate titration calculations. The method comprises providing an amount of sample; providing a light source and an optical sensor with the sample disposed there between, the optical sensor comprising a threshold value; adding to the sample at least one reagent so that the sample undergoes a first color change and causes the measurement by the optical sensor to cross the threshold value in first direction; titrating the sample with a titrant to induce a second color change and the measurement by the optical sensor crosses the threshold value in a second direction opposite the first, the titrating the sample comprising adding a flow of titrant to the sample at a plurality of injection points in a continuous flow process, each injection point associated with an optical sensor, and wherein, at each subsequent injection point, the flow rate of the titrant added to the sample is greater than the flow rate of the titrant at the previous injection point; determining the flow rate of the titrant necessary to induce the second color change; and calculating, using the determined flow rate, the amount of the desired component in the solution.
Patent NZ-714269-A (NZ)
Title: A tiltable bracket for a rain gutter of a building
Inventor: PAUL EDMUND GILL
IPC: E04D13/076
Filed: 2015-11-17
Abstract: The invention is a tiltable bracket assembly for a rain gutter of a building, the assembly including an elongate clip configured to engage with an edge of the rain gutter; and a support bracket, wherein the support bracket includes a vertical element and a horizontal element, wherein the horizontal element including a hinged flap for a base of the rain gutter; characterised in that the vertical element of the support bracket includes a track for the elongate clip, and wherein the horizontal element of the support bracket includes a slot for the elongate clip. The elongate clip is configured to slide along the vertical element of the support bracket to engage and disengage with the upper rear edge of the rain gutter. When disengaged, the flap can be articulated to facilitate the pivotal movement of the rain gutter. This allows the gutter to be easily emptied or cleared of leaves or snow of the like as required.
Patent NZ-715967-A (NZ)
Title: Rhizomania-resistant gene
Inventor: TÖRJÈK OTTO
IPC: C12N15/113
Filed: 2014-06-06
Abstract: The invention relates to a novel nucleic acid molecule, which encodes a polypeptide that can give a plant, in particular a plant of the genus Beta, in which the polypeptide is expressed, resistance to a pathogen, in particular to “Beet Necrotic Yellow Vein Virus”, and a preferred nucleic acid molecule that encodes the RZ-3 gene of Beta maritima, derivatives and homologues thereof. The invention further relates to vectors, to transgenic plant cells, to transgenic plants, to methods for the production thereof and to methods for identifying a nucleic acid molecule that provides resistance.
Patent NZ-719963-A (NZ)
Title: Tire tread including serrations in recessed pockets of groove sidewall
Inventor: JACOBS JEREMY
IPC: B60C11/13
Filed: 2014-11-07
Abstract: The present invention relates to improving traction of a vehicle tire. The invention provides a tire comprising: first and second laterally spaced sides; and a tread interposed between the first and second sides. The tread includes a tread surface having at least one groove therein and facing first and second sidewalls separated by a groove bottom surface. A first pocket region of recessed serrations extend over at least a portion of the first sidewall A second pocket region of recessed serrations extend over at least a portion of the second sidewall. The serrations of the first and second pocket regions are staggered in a circumferential direction relative to one another. The invention therefore includes a first and second “pocket region of recessed serrations”. This arrangement provides recessed serrations do not protrude into the tread groove. This benefit relates to maintaining water flow through the groove which has the effect of maximizing resistance to hydroplaning while still providing enhanced snow traction. When serrations protrude into the tread groove, the serrations reduce the volumetric capacity of the tread groove and interfere with water flow through the tread groove, thus reducing the overall hydroplaning resistance of the tread design.
Patent NZ-726932-A (NZ)
Title: Antibodies directed against cd127
Inventor: POIRIER NICOLAS
IPC: A61K39/00
Filed: 2015-06-10
Abstract: The invention relates to antibodies directed against CD127, the alpha chain of the interleukin 7 (IL-7) receptor IL-7R), and which have antagonist properties for IL-7-IL-7R interaction, may present cytotoxic activity against CD127 positive cells but do not increase the maturation of dendritic cells (DCs) induced by TSLP, a cytokine also using CD127 as part of its receptor. Alternatively, or in addition, these antibodies do not induce the internalization of CD127 and/or inhibit the IL7-induced internalization of CD127. According to another aspect of the invention antibodies are provided which recognize a human CD127 epitope comprising sequences from the 2b site of CD127, in particular the epitope comprising comprises the human CD127 sequences of domain D1 and of the 2b site of CD127, in particular the epitope comprises at least one sequence from D1 comprising SEQ ID No: 115 (in particular comprising SEQ ID No: 10) and/or SEQ ID No: 111 and / or a sequence from the 2b site comprising the sequence of SEQ ID No: 116 and optionally also comprises SEQ ID No: 117 (in particular comprises SEQ ID No: 111).The antibodies of the invention are suitable for use inorder to remedy to a condition diagnosed in a human patient which results from pathogenesis related to lymphopoiesis, when IL-7 signalling pathways provide contribution to said pathogenesis, especially when an increase in the maturation, more precisely the upregulation of costimulatory molecules, of dendritic cells is undesirable.
Patent NZ-727856-A (NZ)
Title: Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
Inventor: LEUTHNER BRIAN
IPC: A61M5/00
Filed: 2012-04-05
Abstract: Sterile kits of a medicament formulated for local or direct administration into a cerebral ventricle for treatment of delayed cerebral ischemia due to a brain injury in a human, the pharmaceutical composition comprising a flowable, sustained release microparticulate composition comprising a pharmaceutical carrier and a therapeutic amount of a therapeutic agent selected from: a dihydropyridine L-type voltage dependent calcium channel inhibitor such as nimodipine, an endothelin (ET) receptor antagonist, a transient receptor potential (TRP) channel antagonist; wherein the pharmaceutical carrier comprises one or more of sodium carboxymethylcellulose, sorbitol, hyaluronic acid, or dextran; and each microparticle comprises a polymer matrix such as D,L-lactide-co-glycolide having a therapeutic agent dispersed throughout the microparticle, such that the therapeutic agent is not centrally located in a core surrounded by a coating.
Patent NZ-751449-A (NZ)
Title: Novel compounds and compositions for inhibition of fasn
Inventor: BAIR KENNETH
IPC: A61K31/4965
Filed: 2014-03-11
Abstract: The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
Patent NZ-768192-A (NZ)
Title: Apparatus for generating aerosol from an aerosolisable medium, an article of aerosolisable medium and a method of determining a parameter of an article
Inventor: MOLONEY PATRICK
IPC: A24F40/20
Filed: 2019-03-27
Abstract: An apparatus for generating aerosol from an aerosolisable medium is disclosed. The apparatus comprises: a housing; a chamber for receiving an article comprising aerosolisable medium and including a marker; and a controller. The controller is configured to receive: a first input indicative of a rate of movement of the article, received in use, in the chamber; and a second input indicative of a parameter of said article. At least the second input is determined based on the marker.
Patent NZ-770652-A (NZ)
Title: Health based actuator allocation
Inventor: SAUNDERS CHRISTOPHER
IPC: G05D1/08
Filed: 2019-08-19
Abstract: A set of one or more desired forces or desired moments associated with an aircraft having a plurality of rotor modules is received. A plurality of health metrics associated with the plurality of rotor modules is received. A plurality of commands for the plurality of rotor modules is determined based at least in part on the set of desired forces or desired moments and the plurality of health metrics. The plurality of commands is sent to the plurality of rotor modules where each rotor module in the plurality of rotor modules is configured to perform a corresponding command in the plurality of commands.
Patent PT-103715-A (PT)
Title: Instrumento para pulsação dum escoamento em conduta fechada
Inventor: LOPES JOSE CARLOS BRITO
IPC: F15C1/22
Filed: 2007-04-11
Abstract: A presente invenção consiste num instrumento com capacidade para induzir uma oscilação de caudal e pressão numa corrente de fluido que circula em conduta fechada. A dita corrente é introduzida através duma entrada (2) numa câmara (1) equipada com um ou mais dispositivos de emissão sonora (4), com uma frequência e amplitude de vibração determinadas por uma ou mais fontes (6) de sinal eléctrico, que fazem oscilar um ou mais diafragmas (5) de forma a gerar um escoamento pulsado em uma ou mais saídas da câmara (3), podendo incorporar instrumentos de medição (7) para as características da vibração da corrente de saída (3) . A corrente pulsada pode ser usada como jacto de alimentação a dispositivos, tais como micro reactores, precipitadores, misturadores estáticos, jactos de corte, jactos de erosão ou polimento, injecção em câmaras de combustão ou explosão, e alimentação de emulsionadores.
Patent PT-103791-A (PT)
Title: Teclado baseado em polímero, co-polímero ou compósito com propriedades piezo- e/ou piroeléctricas e respectivas utilizações
Inventor: MENDEZ SENENTXU LANCEROS
IPC: H03K17/96
Filed: 2007-07-17
Abstract: A INVENÇÃO REFERE-SE A UM NOVO TECLADO BASEADO NUM FILME (11) POLIMÉRICO, CO-POLÍMERICO OU COMPÓSITO COM PROPRIEDADES PIEZO- E PIROELÉCTRICAS CAPAZ DE RECEBER UM SINAL TÁCTIL E FORNECER UMA RESPOSTA EM FORMA DE UM SINAL ELÉCTRICO. O SISTEMA DA PRESENTE INVENÇÃO INCLUI UMA OU MAIS TECLAS (10), SENDO CADA UMA CONSTITUÍDA POR UM FILME PIEZOELÉCTRICO (11) COM CONTACTOS CONDUTORES ELÉCTRICOS, TRANSPARENTES OU NÃO, NO TOPO E POR BAIXO DO FILME E POR UMA CAMADA INFERIOR DE ELÉCTRODO DE MASSA (13). A PRESENTE INVENÇÃO PERMITE A UTILIZAÇÃO DE APENAS UM FILME PIEZOELÉCTRICO (11) SEM ALIMENTAÇÃO EXTERNA, A UTILIZAÇÃO DE LIGAÇÕES AOS ELÉCTRODOS QUE FORMAM AS TECLAS (10) QUE CONVERGEM NUM DOS LADOS DO TECLADO E ESTÃO DISPONÍVEIS NOS PONTOS (12) PARA SE EFECTUAR A LIGAÇÃO AO CIRCUITO DE FILTROS ACTIVOS EM VEZ DE AMPLIFICADORES NA ELECTRÓNICA DE LEITURA, BEM COMO A POSSIBILIDADE DE INTRODUÇÃO NESTES TECLADOS, DE NOVAS FUNCIONALIDADES, SEMELHANTES AOS SENSORES DE TACTO, MEDIANTE A DISTINÇÃO ENTRE UM SINAL PIROELÉCTRICO E PIEZOELÉCTRICO DE UMA TECLA EM PARTICULAR, DIFERENCIANDO SINAIS GERADOS POR EFEITO DA PRESSÃO E POR VARIAÇÃO DE TEMPERATURA.
Patent RO-94902-A (RO)
Inventor: BALINT SANDOR
IPC: A01N57/24
Filed: 1985-07-12
Abstract: PCT No. PCT/HU85/00044 Sec. 371 Date Mar. 13, 1986 Sec. 102(e) Date Mar. 13, 1986 PCT Filed Jul. 17, 1985 PCT Pub. No. WO86/00904 PCT Pub. Date Feb. 13, 1986.The present invention refers to new etherified hydroxy-alkyl phosphonic acid derivatives of the general formula (I)   <IMAGE> (I)  wherein R stands for 2,3-dihydro-2,2-dimethyl-benzofuran-7-yl, 4-methyl-coumarin-7-yl, 2,2,4-trimethyl-(2H)-chromen-5-yl or 2,2,4-trimethyl-(2H)-chromen-7,yl, R1 and R2 are the same or different and stand for hydrogen, C1-8 alkyl, C1-4 halogen-alkyl, C1-4 alkoxy-C1-2 alkyl, Me stands for a monovalent cation. The new compounds can be used as active ingredients of plant growth regulating agents.
Patent RU-94021390-A (RU)
Inventor: LOTSMANENKO V V
IPC: B23F5/20
Filed: 1994-06-07
Abstract: FIELD: manufacture and repair of single- thread and multiple-thread worm wheels and reducers. SUBSTANCE: method involves simultaneous rotational motion of cutter about its axis of rotation, circular feed about axis coinciding with axis of working worm and radial feeding in direction of rotational axis of worm wheel, when axial plane of worm cutter coincides with middle plane of worm wheel. Parameters of worm wheel and working worm and center-to-center distances of working and lathe meshes the moment of termination of tooth cutting process are equal. Angular speeds of worm cutter of worm wheel to be cut are related through gear ratio equal to wheel teeth number and worm cutter entry number ratio. The number of worm cutter entries is equal to the number of working worm entries. Cutting depth of worm cutter is equal to wheel tooth height. EFFECT: increased efficiency, wider operational capabilities and improved quality of worm wheels. 2 cl, 2 dwg
Patent RU-94023747-A (RU)
Inventor: PLATONOV E I
IPC: F41C3/14
Filed: 1994-06-23
Abstract: FIELD: sports, hunting and military weapons. SUBSTANCE: drum of evolver is displaced forward relative to handle, firing lever is put on pawl, trigger acts on connecting rod without use of intermediate mechanism, handle is raised to level of barrel and is turned through 135 deg so that axis of elbow bone of shooter coincides with axis of bore. EFFECT: enhanced stability of revolver during shooting.
Patent RU-94025197-A (RU)
Inventor: ZHARIKOV I F
IPC: E21C37/00
Filed: 1994-07-12
Abstract: FIELD: mining industry, intended for blasting at open-cut mining. SUBSTANCE: the known methods of charging and blasting of blast holes do not provide for self-destruction of the explosive charge in case of a failure of detonation. At charging of the hole with explosive and means of its initiation a ring or loop of detonating cord is made in the section of the detonating cord projecting beyond the explosive charge in its height; then a shell of film material is lowered in the hole, filled with an aqueous solution of alkali; and the free end of the detonating cord is connected to the detonating cord line. EFFECT: reliable self-destruction of the explosive charge on the bases of ammonium nitrate.
Patent RU-94030024-A (RU)
Inventor: ERMOSHKIN A G
IPC: A01F15/00
Filed: 1994-08-09
Abstract: FIELD: agriculture. SUBSTANCE: method involves placing delivered hay or straw bales with their sides onto trench bottom and one onto another; completely filling trench with bales and providing placing of additional bales so that bale pile extends 2-3 m above trench. Placing of bales on their sides is preferred because recompaction process is conducted without changing bale length and, consequently, binding material, such as cord or wire, is under the same static stress. Method further involves covering formed bale pile with layer of ground straw (0.5-0.7 m) to isolate from moisture of plant juices; heaping up formed pile with succulent green plant mass of 0.5-0.7 m thickness and moisture content exceeding 80%. As a result hey and straw bales are pressed by green succulent plant mass and further compacted in trench. EFFECT: increased efficiency by reduced volume and increased density of bales.
Patent RU-94042214-A (RU)
Inventor: LEUN E V
IPC: G01B9/02
Filed: 1994-11-24
Abstract: FIELD: measurement technology, fibre optics, interferometry. SUBSTANCE: invention may be used instrument pressure converters. Proposed fiber-interferential system of pressure measurement has radiation source, light guides, sensitive element, directional coupler, recorder. It differs from other known systems by insertion of amplitude-spectral modulator of optic radiation connected to radiation source composed of control unit and modulator of spectrum and amplitude modulator connected in series, output of the latter is output of amplitude-spectral modulator connected to directional coupler. One output of directional coupler is connected to recorder and the other one - through light guide to sensitive element. Sensitive element presents laminated structure of optically transparent materials forming holographic filter. Recorder has photodetector and frequency meter connected in series. Proposed design of fiber-interferential system of pressure measurement makes it possible to increase sensitivity and consequently precision of measurement with relative simplicity of system. Salient features of system are small dimensions and possibility of its usage in places difficult to access. EFFECT: simplified design, increased sensitivity and small dimensions. 1 cl, 5 dwg
Patent RU-94043129-A (RU)
Inventor: SOROKIN L JU
IPC: H02K15/12
Filed: 1994-12-02
Abstract: FIELD: electromechanical engineering. SUBSTANCE: electrical machine shaft seal has fixed member 1 mounted on shaft 3 and moving member 2 pressed to fixed one by spring 7 and fixed in position by pin 8. Machine accommodates disk 10 fixed on spherical pin 11 and pressed by spring 12 through angle smaller than 90 deg. to horizontal axis. EFFECT: improved design. 1 dwg
Patent RU-94046274-A (RU)
Inventor: BRUNO PIRONE
IPC: B01D3/42
Filed: 1993-06-16
Abstract: FIELD: beverage production. SUBSTANCE: beverages such as mineral water (2) are prepared from any water material in the following way. Water material 3 is demineralized by distillation; distillate 23 is sterilized and remineralized by way of its combining with salt additive 35 of specified makeup. Apparatus 1 is also described. EFFECT: enhanced efficiency of process.
Patent RU-95101491-A (RU)
Inventor: BOBROV R V
IPC: B62D7/14
Filed: 1995-02-01
Abstract: FIELD: transport engineering; wheeled vehicles with front and rear steerable wheels. SUBSTANCE: steering system has front and rear steerable wheel drives with power cylinders supplied by hydraulic pumps through hydraulic distributors and coupled by rear wheel control arrangement made in form of mechanical coupling with variable lengths sleeve whose driving link is coupled with front steerable wheel drive and driven link, with hydraulic distributor of rear steerable wheel drive. Driven link has device for automatic reset in neutral position. rear steerable wheel drive has additional hydraulic distributor installed between power cylinder and hydraulic distributor of rear steerable wheel drive. Variable length sleeve has rear steerable wheel position pickup coupled with control drive of additional hydraulic distributor. EFFECT: enhanced stability of vehicle at straight driving.
Patent RU-95101764-A (RU)
Inventor: GUREVICH E JA
IPC: G06K9/68
Filed: 1995-02-06
Abstract: FIELD: optics. SUBSTANCE: in compliance with process image of object is presented in the form of input matrix of numbers. Each element of it corresponds to level of intensity/density of signal generated by object. Dimension of window with which aid input matrix of numbers is examined is chosen depending on analyzed texture of object at least half as large as dimension of input matrix of numbers. Movement spacing of window is set equal to dimension of window. At least one textural indication is selected which characterizes texture of object and value of selected indication for initial position of window is found for it and later for all windows. Interval of values of calculated textural indication is divided into two subintervals and each subinterval is assigned code. Identity of calculated value of textural indication for each window on input matrix of numbers is established to correspond to proper subinterval and this calculated value of textural indication is coded by code of corresponding subinterval. As result output matrix is obtained each element of which corresponds to one window on input matrix of numbers. At least one indication characterizing group of elements of output matrix with same code is chosen and value of selected indication by which image of texture of object is identified is calculated. EFFECT: improved authenticity of analysis.
Patent RU-95102155-A (RU)
Inventor: PRAGER I L
IPC: G01M17/00
Filed: 1995-02-14
Abstract: FIELD: testing and diagnostics. SUBSTANCE: proposed bed makes it possible to diagnose with high degree of accuracy troubles of most important units of motor vehicle (engine, transmission box, clutch and the like) during its running by noises: squeaking, knocking, roar, crackling and so on. Sound recorders recording sounds in the form of digital codes into computer and using these codes for processing in agreement with special programs and algorithms were not used until recently for the specified purposes as there was no such physical capability. It emerged recently together with development of multimedia facilities. Automation of diagnostics process completely excluding personnel is achieved as information to computer is transmitted over radio channel with the aid of transmitter which is installed together with sound sensors (microphones) on motor vehicles. Information from microphone is sent through commutator playing role of information converter (changes duration of information and logic of its transmission) to transmitter which also transmits vehicle plate number generated by microcircuit mounted on it. EFFECT: complete automation of diagnostics process.
Patent RU-95106618-A (RU)
Inventor: KRAVTSOVA T A
IPC: A61K35/78
Filed: 1995-04-25
Abstract: FIELD: medicine. SUBSTANCE: antiinflammatory agent has natural components only and involves essential oils taken at small concentrations, sage concentrate and an aqueous-spirituous liquid at the following ratio of components, kg/g: mint essential oil 0.02-0.06; common worm-wood essential oil 0.4-1.0; rose essential oil 0.02-0.08; anise essential oil 0.025-0.1; sage concentrate 0.5-2.5; rectified ethyl alcohol 20-50, and water - the rest. Agent can be used in stomatology, gynecology, rhinolaryngology as bactericidal, deodorizing, antiinflammatory and analgetic substance. EFFECT: enhanced effectiveness, broadened assortment.