baber/WOPTO huggingface dataset:
Patent AU-2021225952-A1 (AU)
Title: Method for producing natural killer cells from pluripotent stem cells
Inventor: QIAN YU
IPC: A61P35/00
Filed: 2021-02-26
Abstract: The present disclosure provides, among other things, a method for efficiently producing natural killer cells from induced pluripotent cells. The method includes the steps of: (I) culturing pluripotent stem cells in a culture medium to produce CD56+/CD3- immune cells.
Patent AU-2021236575-A1 (AU)
Title: Radiotherapy seeds and applicators
Inventor: KELSON ITZHAK
IPC: G21G4/08
Filed: 2021-09-24
Abstract: A casing holding one or more brachytherapy seeds for implanting in a patient, which in 
5 turn carry atoms of a radioactive element for radiotherapy treatment is filled with a viscous liquid 
in a manner preventing radiation from the one or more brachytherapy seeds from exiting the 
casing. The casing may include a metallic or non-metallic elongated tube configured for insertion 
into tissue or a vial for delivering a seed to a physician for insertion into a needle.
Patent AU-2021242321-A1 (AU)
Title: RNAi agents for inhibiting expression of PNPLA3, pharmaceutical compositions thereof, and methods of use
Inventor: NICHOLAS ANTHONY
IPC: A61K31/713
Filed: 2021-03-26
Abstract: The present disclosure relates to RNAi agents,
Patent AU-2021245131-A1 (AU)
Title: Refrigerator
Inventor: LEE JONGHYUN
IPC: F25D23/02
Filed: 2021-10-06
Abstract: An embodiment of the present disclosure relates to a refrigerator and the refrigerator includes a 
cabinet configured to form a storage space, a door configured to open and close the storage space, 
and a gap adjusting device configured to be provided between the cabinet and the door and to adjust 
a gap between the cabinet and the door, in which the gap adjusting device includes a seating part 
formed on the door; and an adjusting member which is detachably mounted on the seating part and 
is in contact with the cabinet in a state where the door is closed, a plurality of adjusting parts having 
different heights are formed on the adjusting member, and a gap between the cabinet and the door is 
adjusted according to a combination of a contact surface between the seating part and the adjusting 
part selected when the adjusting member is mounted.
Patent AU-2021254287-A1 (AU)
Title: Improved methods for evaluating liver function
Inventor: EVERSON GREGORY THOMAS
IPC: G16H50/30
Filed: 2021-04-09
Abstract: Improved methods and kits are provided for non-invasively evaluating liver function of a patient including rapidly and efficiently processing, detecting, and quantifying distinguishable compounds from patient blood or serum samples. A method is provided for estimating risk of experiencing a clinical event in 1 year for an individual patient having a chronic liver disease. Methods for determining hepatic reserve in a subject are provided.
Patent AU-2021263297-A1 (AU)
Title: Bumpless superconductor device
Inventor: CANTALOUBE CHRISTOPHER A
IPC: H01L27/18
Filed: 2021-03-25
Abstract: An integrated circuit (50) is provided that comprises a plurality of conductive contact pads (60) on a surface of a first substrate (52), and a dielectric layer (54) overlying the first substrate and the conductive contact pads, which may be coupled to respective qubits (62). A second substrate (56) overlies the dielectric layer, and a plurality of superconducting contacts (58) extend through the second substrate and the dielectric layer such that each superconducting contact is aligned with and in contact with a respective conductive contact pad and may be coupled to a respective resonator (64). Corresponding fabrication methods are disclosed as well.
Patent AU-2021268606-A1 (AU)
Title: Imino sulfanone inhibitors of ENPP1
Inventor: COGAN DEREK A
IPC: C07D401/06
Filed: 2021-05-03
Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to sulfoximine- based inhibitors of ENPP1 of Formula (I) and methods of their use for treating disease mediated by ENPP1.
Patent AU-2021286956-A1 (AU)
Title: Process for extracting a hyaluronic acid from a fungus, a hyaluronic acid of plant origin and use thereof
Inventor: CERANA GIORGIO STEFANO
IPC: C12P19/26
Filed: 2021-06-08
Abstract: Process for extracting from a plant starting material, such as a fungus, for the preparation of a hyaluronic acid or a salt thereof (HA) having a weight average molecular weight comprised from 10 kDa to 600 kDa.
Patent AU-2021288734-A1 (AU)
Title: Chimeric antigen receptor cell
Inventor: PULÉ MARTIN
IPC: C12N5/0783
Filed: 2021-06-09
Abstract: The present invention relates to a cell which comprises a chimeric antigen receptor (CAR) comprising a binding domain which binds a first epitope of a tumour antigen; and a polynucleotide which encodes a bi-specific protein which comprises a first binding domain which binds a second epitope of said tumour antigen; and a second binding domain which binds a cell surface antigen. The present invention also provides CAR systems, nucleic acids, vectors, pharmaceutical compositions and pharmaceutical compositions for use in the treatment and/or prevention of disease.
Patent AU-2021306864-A1 (AU)
Title: Apparatus and method for electron irradiation scrubbing
Inventor: RAMSAY WILLIAM JAMIESON
IPC: C23C16/44
Filed: 2021-07-06
Abstract: There is provided a dielectric barrier electrical discharge apparatus, system and method. The apparatus comprises at least two electrodes arranged in use to provide at least one anode and at least one cathode an electric field thereby being establishable therebetween, the at least two electrodes being separated to allow a fluid to be present between the electrodes in use. At least one of the electrodes has a dielectric portion connected to at least part of said electrode, and a sub-macroscopic structure is connected to at least one of the electrodes or dielectric portion.
Patent AU-2021357098-A1 (AU)
Title: Temperature monitoring and control for negative pressure wound therapy systems
Inventor: LAITENBERGER PETER GEORG
IPC: A61M1/00
Filed: 2021-09-22
Abstract: A negative pressure wound therapy can include a negative pressure source configured to provide negative pressure to a wound of a patient covered by a wound dressing, first sensor and second sensors configured to measure temperature of the negative pressure system, electronic control circuitry configured to control operation of the negative pressure source responsive to temperature measured by the first sensor, and a programmable controller configured to control operation of the negative pressure source responsive to temperature measured by the second sensor, the controller configured to control operation of the negative pressure source independently of the electronic control circuitry.
Patent AU-2021360726-A1 (AU)
Title: Catheter assembly with directional port opening
Inventor: MA YIPING
IPC: A61M39/22
Filed: 2021-10-04
Abstract: A vascular access device including a catheter adapter (12), a port opening (28), and an elastomeric valve (24). The catheter adapter extends along a longitudinal axis (20) and includes a proximal end (14), a distal end (16), and a lumen (18) extending therebetween. The port opening is formed in a surface of the catheter adapter in fluid communication with a side port (22) of the catheter adapter and the lumen. A structural geometry of the port opening directs a fluid into the lumen in a proximal direction. The elastomeric port valve is disposed within the lumen and configured to deform in response to a transverse force applied thereto. A proximal gap may result between the inner wall forming the lumen and a proximal side of the elastomeric port valve, thereby opening a fluid path.
Patent AU-2021383318-A1 (AU)
Title: Methods of operating quantum computing systems for amplitude estimation
Inventor: GIURGICA-TIRON TUDOR
IPC: G06N10/00
Filed: 2021-11-22
Abstract: This disclosure relates to enhanced methods of operating quantum computing systems to perform amplitude estimation. More than that, the methods may be tuned to accommodate for specific noise levels (e.g., in given a quantum device). Embodiments also enble quantum computing systems to perform amplitude estimation faster than amplitude estimation algorithms performed using a classical (non-quantum) computer.
Patent AU-2022201100-A1 (AU)
Title: Non-HLA matched humanized NSG mouse model with patient-derived xenograft
Inventor: KECK JAMES
IPC: A01K67/027
Filed: 2022-02-18
Abstract: The invention described herein provides non-HLA matched humanized mouse model 
(e.g., NSG mouse model) with patient-derived xenograft (PDX), as well as methods of 
making and using the same.
Patent AU-2022201742-A1 (AU)
Title: The use of inhibitors of Bruton's tyrosine kinase (Btk)
Inventor: BUGGY JOSEPH J
IPC: A61P35/02
Filed: 2022-03-14
Abstract: Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a 
subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes 
defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from 
one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined 
expression profile.
Patent AU-2022217471-A1 (AU)
Title: Device for discharging mushrooms from a conveyor
Inventor: LEMMEN JACOBUS ALEXANDER JOZEF
IPC: A01G18/60
Filed: 2022-02-07
Abstract: The present invention relates to a device for discharging mushrooms from a conveyor, comprising a mushroom conveyor, in particular a conveyor belt and/or an endless conveyor, for conveying the mushrooms in a direction of conveyance; wherein the mushroom conveyor has a surface for carrying the mushrooms; and the mushroom conveyor being guided along a trajectory from a charging location such as a picking location to a discharging location, such as a filling station for mushroom containers, as well as a twister, located at the discharging location, for at least locally twisting a plane in which the surface of the mushroom conveyor lies.
Patent AU-2022220762-A1 (AU)
Title: Module for use in preparing a prefabricated structure, method for manufacturing same and transport frame
Inventor: SEARLES DARRELL ALBERT
IPC: E04B1/343
Filed: 2022-02-10
Abstract: The present invention provides a reinforced concrete module for use in preparing a prefabricated structure comprising a horizontal slab, four corner columns, perimeter beams extending downwardly from a respective longitudinal and transversal edges of the horizontal slab and extending between and connected to adjacent columns; at least two transverse ribs located on an underside of the horizontal slab and extending between two opposing perimeter beams, wherein the module is fabricated as a unitary body. Also provided is a method for fabricating the module, as well as a transport frame configured to support a module on a transport vehicle.
Patent AU-2022231762-A1 (AU)
Title: A bundle adjustment system
Inventor: COPE SIMON
IPC: G06T7/55
Filed: 2022-09-15
Abstract: A bundle adjustment system is disclosed for determining a solution for orientation 
information associated with a plurality of image frames captured by at least one rolling 
5 shutter camera, wherein the at least one rolling shutter camera is part of a rotating 
camera lens type imaging system having a camera lens that moves in an oscillating 
manner as image frames are captured. The system is arranged to define a plurality of 
pose time domain polynomials for the rolling shutter camera, the pose time domain 
polynomials together defining pose information for the rolling shutter camera for 
10 scanlines of an image frame captured by the rolling shutter camera, and each pose 
time domain polynomial including a plurality of parameters to be adjusted in a bundle 
adjustment process. The system is also arranged to carry out a bundle adjustment 
process using the pose time domain polynomials to produce a bundle adjustment 
solution wherein the pose time domain polynomial parameters are adjusted to reduce 
15 error. The bundle adjustment process is arranged to use a bundle adjustment cost 
function wherein a cost measure of the cost function is a minimum distance error 
between 2 rays projected from 2 different locations of a tie point feature.
Patent AU-2022242863-A1 (AU)
Title: Systems and methods for determining state data for agricultural parameters and providing spatial state maps
Inventor: ALLGAIER RYAN
IPC: A01C21/00
Filed: 2022-01-28
Abstract: Described herein are systems and methods for determining state data for agricultural parameters during agricultural applications and providing spatial state maps. In one embodiment, a computer implemented method comprises obtaining as applied data of an agricultural implement (10) as the agricultural implement (10) passes through a field for an agricultural application. The computer implement method also includes processing the as applied data to calculate data for a parameter of the agricultural application and determining state data (e.g., quality indicator state) for each row unit (200) based on the data for the parameter and at least one of default configuration settings or user configuration settings for the quality indicator state.
Patent AU-2022251301-A1 (AU)
Title: 3d printed monoblock orthopaedic surgical implant with customized patient-specific augment
Inventor: KEEFER RYAN C
IPC: A61F2/30
Filed: 2022-03-30
Abstract: An acetabular shell component includes a solid substrate (12), a porous outer layer (16) coupled to the solid substrate, a porous inner layer (14) coupled to the solid substrate, and an inner bearing (18) coupled to the porous inner layer. One or more adjuncts (40) extend outward from the porous outer layer. Each adjunct includes an outer surface that defines a customized patient-specific negative contour shaped to conform to a positive contour of a patient's bone. A method for manufacturing the acetabular shell component using an additive manufacturing process is also disclosed.
Patent AU-2022252970-A1 (AU)
Title: A heater
Inventor: CRAWFORD KYLE
IPC: H05B3/28
Filed: 2022-04-01
Abstract: A heater coupon is disclosed having a ceramic block with a first surface and a second surface, at least one heater trace formed within the ceramic block and a connector for electrically connecting the at least one heater trace to a PCB (printed circuit board). The connector may connect at one end to the heater coupon and at the other end to the PCB. The connector may provide a direct connection between the heater coupon and the PCB. The connector may comprise a first connecting arm for connecting with respect to the first surface of the ceramic block and a second connecting arm for connecting with respect to the second surface of the ceramic block.
Patent AU-2022259810-A1 (AU)
Title: Systems for and methods of positioning solar panels in an array of solar panels with spectrally adjusted irradiance tracking
Inventor: Ma Yu Dong
IPC: F24S50/40
Filed: 2022-10-27
Abstract: A solar tracking system comprises multiple solar panel modules forming a grid of solar panel 
modules, wherein the multiple solar panel modules are movable relative to a solar source 
independently of each other; and a control system configured to orient each of the multiple 
solar panel modules to the solar source independently of each other based on a performance 
model to optimize an energy output from the grid of solar panel modules, wherein the 
performance model predicts an energy output from the grid of solar panel modules based on a 
topography of the area containing the grid of solar panel modules and weather conditions 
local to each of the solar panel modules.
Patent AU-2022261123-A1 (AU)
Title: Methods and compositions for treating mydriasis, glaucoma, and other ocular conditions
Inventor: PEPOSE JAY STUART
IPC: A61K31/417
Filed: 2022-04-22
Abstract: The invention provides methods, compositions, and kits containing an alpha adrenergic antagonist such as phentolamine, either alone or in combination with a muscarinic acetylcholine receptor agonist such as pilocarpine, for treating conditions of the eye. Specifically, the invention provides methods of treating patients suffering from mydriasis, glaucoma (such as angle-closure glaucomas or narrow angle attack), as well as improving aspects of vision in dim-light such as improved visual performance, reduced pupil diameter and reduced aberrant focus of scattered light.
Patent AU-2022268269-A1 (AU)
Title: Sensors and methods for measuring pH
Inventor: FELDMAN BENJAMIN J
IPC: A61B5/145
Filed: 2022-11-07
Abstract: It can be particularly difficult to measure pH in vivo using current electrochemical sensors due to 
sensor drift and fouling of the sensor surface. Sensors suitable for measuring pH, particularly in 
vivo, may comprise: a sensor tail comprising a first working electrode, a second working electrode, 
and at least one other electrode; a first active portion located upon the first working electrode, the 
first active portion comprising a substance having pH-dependent oxidation-reduction chemistry; 
and a second active portion located upon the second working electrode, the second active portion 
comprising a substance having oxidation-reduction chemistry that is substantially invariant with 
pH. A difference between a first signal from the first active portion and a second signal from the 
second active portion may be correlated to a pH value for a fluid.
Patent AU-2022269811-A1 (AU)
Title: Orexin receptor agonists and uses thereof
Inventor: CHOVATIA PRAFULKUMAR
IPC: C07D498/10
Filed: 2022-05-03
Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salt thereof, wherein n, m, A
Patent AU-2022280090-A1 (AU)
Title: Facile fabrication of multivalent vo x/graphene nanocomposite electrodes for energy storage devices with high energy density
Inventor: HUANG AILUN
IPC: H01G11/24
Filed: 2022-05-27
Abstract: Disclosed herein are vanadium active materials, methods of making the same, and energy storage devices comprising the same. The vanadium active material may be incorporated into an electrode with a graphene scaffold, the graphene scaffold having a three-dimensional network of interconnected pores, a first vanadium oxide in a first oxidation state, and a second vanadium oxide in a second oxidation state.
Patent AU-2022284804-A1 (AU)
Title: Gene editing systems comprising a crispr nuclease and uses thereof
Inventor: SCOTT DAVID
IPC: C12N15/11
Filed: 2022-06-01
Abstract: A gene editing system comprising : (a) a Type V CRISPR nuclease polypeptide or a first nucleic acid encoding the Type V CRISPR nuclease polypeptide; (b) a reverse transcriptase (RT) polypeptide or a second nucleic acid encoding the RT polypeptide; (c) a guide RNA (gRNA) or a third nucleic acid encoding the gRNA, wherein the gRNA comprises one or more binding sites recognizable by the Type V CRISPR nuclease (CRISPR nuclease binding sites) and a spacer sequence specific to a target sequence within a genomic site of interest, the target sequence being adjacent to a protospacer adjacent motif (PAM); and (d) a reverse transcription donor RNA (RT donor RNA) or a fourth nucleic acid encoding the RT donor RNA, wherein the RT donor RNA comprises a primer binding site (PBS) and a template sequence.
Patent AU-2022323712-A1 (AU)
Title: Alarm peripheral
Inventor: PIEDBOIS JULIEN
IPC: G08B19/00
Filed: 2022-08-02
Abstract: The invention relates to an alarm peripheral (10) having a sensor (12), an energy storage device (14), a photovoltaic cell (16) and a control unit (18), the control unit (18) having a fire detection module (20) adapted for generating a fire alarm.
Patent AU-2022355995-A1 (AU)
Title: Method for recovering lithium from lithium-containing solution
Inventor: WANG MINGHAO
IPC: C01D15/08
Filed: 2022-09-29
Abstract: A method for recovering lithium from a lithium-containing solution. The method comprises: mixing a lithium-containing solution having an adjusted or unadjusted pH value with a meta-aluminate solution, and adjusting the pH value until the solution is weakly acidic/neutral so as to separate the lithium element in the lithium-containing solution from a system in the form of a Li
Patent AU-2023200651-A1 (AU)
Title: Pressurizing masks, systems and methods
Inventor: O'DONNELL KEVIN PETER
IPC: A61M16/00
Filed: 2023-02-07
Abstract: A respiratory mask or other sealing interface can be used in combination with a nasal 
cannula or other unsealing interface in providing respiratory therapies for the treatment of 
COPD or OSA. The mask can act as a pressure vessel over the top of a nasal cannula, with the 
5 intention of increasing expiratory pressure whilst allowing the nasal cannula to provide a user 
with breathing gases of a high humidity and temperature. The ability to selectively apply 
increased expiratory pressure may be effective in reducing a user's breathing rate and thus 
beneficial in the treatment of respiratory distress.  
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Patent AU-2023200856-A1 (AU)
Title: Systems and methods for preoperative planning and postoperative analysis of surgical procedures
Inventor: DE SOUZA KEVIN MICHAEL
IPC: A61B34/00
Filed: 2023-02-15
Abstract: A system for determining accuracy of a surgical procedure to implant an implant on a patient bone.  
The system including at least one computing device configured to perform the following steps.  
Receive preoperative patient data including preoperative images of the patient bone and planned 
implant position and orientation data. Receive postoperative patient data including postoperative 
images of the patient bone and an implant implanted on the patient bone. Segment the patient bone 
and the implant from the postoperative images of the patient bone and the implant. Register 
separately the patient bone and the implant from the postoperative images to the patient bone from 
the preoperative images. And compare an implanted position and orientation of the implant from the 
postoperative images relative to the patient bone from the preoperative images to the planned 
implant position and orientation data relative to the patient bone from the preoperative images.
Patent AU-2023202813-A1 (AU)
Title: Methods of treating prostate cancer
Inventor: GOTTARDIS MARCO
IPC: A61K31/454
Filed: 2023-05-05
Abstract: Disclosed are methods of treating prostate cancer by administering niraparib to a 
human in need thereof.
Patent AU-2023203460-A1 (AU)
Title: Increasing representation accuracy of quantum simulations without additional quantum resources
Inventor: JIANG ZHANG
IPC: G06N10/00
Filed: 2023-06-02
Abstract: Methods, systems and apparatus for simulating physical systems. In one aspect, a method 
includes the actions of selecting a first set of basis functions for the simulation, wherein the 
first set of basis functions comprises an active and a virtual set of orbitals; defining a set of 
expansion operators for the simulation, wherein expansion operators in the set of expansion 
operators approximate fermionic excitations in an active space spanned by the active set of 
orbitals and a virtual space spanned by the virtual set of orbitals; performing multiple 
quantum computations to determine a matrix representation of a Hamiltonian characterizing 
the system in a second set of basis functions, computing, using the determined matrix 
representation of the Hamiltonian, eigenvalues and eigenvectors of the Hamiltonian; and 
determining properties of the physical system using the computed eigenvalues and 
eigenvectors.  
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