baber/WOPTO huggingface dataset:
Patent NZ-590784-A (NZ)
Title: Pyrazolopyridine kinase inhibitors
Inventor: JIMENEZ JUAN-MIGUEL
IPC: C07D471/04
Filed: 2009-07-22
Abstract: Disclosed are 6-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-amine derivatives as represented by the general formula (I), or pharmaceutically acceptable salts thereof, wherein: R1 and R2 are each independently H, halogen, -OR', -N(R')2, -C(O)OR', -C(O)N(R')2, -NR'C(O)R', -NR'C(O)OR', -CN, -NO2, aliphatic optionally and independently substituted with one or more Ja, or cycloaliphatic optionally and independently substituted with one or more Jb; Q is N, O or S; ring B is a 6-membered monocyclic heteroaromatic ring optionally fused to an aromatic or non-aromatic ring; and ring B is optionally substituted with one Y and independently further optionally and independently substituted with one or more Jc; R3 is absent, H, or alkyl optionally and independently substituted with one or more Ja; R4 is aliphatic, wherein up to three methylene units of R4 are optionally and independently replaced by G', or R4 is optionally and independently substituted with one ring C and independently further optionally and independently substituted with one or more Ja; or R4 is ring C; and wherein the remaining substituents are as defined herein. Representative compounds include N-((4-aminocyclohexyl)methyl)-6-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-amine, N1-(6-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl)-2-methylpropane-1,2-diamine and N-((4-aminocyciohexyl)methyl)-6-(1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(trifluoromethyl)pyridin-2-amine. Further disclosed is a composition comprising a compound or a pharmaceutically acceptable salt thereof as defined above, and a pharmaceutically acceptable carrier, adjuvant, or vehicle for treating or preventing a protein kinase-mediated condition such as asthma, psoriasis, arthritis, rheumatoid arthritis, joint inflammation, multiple sclerosis, diabetes, inflammatory bowel disease, transplant rejection, T-cell leukaemias, lymphomas, and lupus.
Patent NZ-590876-A (NZ)
Title: A coupling arrangment for guardrails which upon telescopic slinding of the rails causes an increasing clamping force between them
Inventor: JAMES DALLAS REX
IPC: E01F13/00
Filed: 2011-12-23
Abstract: An energy absorbing slider assembly (100) for guardrails (1001, 1002, 1003) is disclosed. The slider assembly includes a front section and a back section. The front section is adapted to conform to the cross sectional profile of rails forming the terminal end of a guardrail, or other barrier, to which the slider will be fitted in use. The front section in combination with the back section creates an internal space between them, the internal space dimensioned, so as to in use, be capable of substantially surrounding both an associated first rail and an associated second rail of the terminal end as well as at least two further rails located downstream of said first and second rail. The slider assembly has first and second opposed portions and is configured so that the first and second opposed portions can move with respect to each other to apply an increasing compressive force to the rails as the slider assembly travels along during an impact causing telescoping of the rails. Two possible embodiments are disclosed, one whose clamping force increases in a steady manor and one whose clamping force increases in a stepped manor.
Patent NZ-591762-A (NZ)
Title: Monitoring and control system for commodity loading
Inventor: MYLET NEIL T
IPC: H04N7/18
Filed: 2009-08-18
Abstract: 591762 Disclosed is a system (50) for in-vehicle monitoring and control of a loading system of a commodity loading facility. A control device is adapted to interface with the loading system of a commodity loading facility and has a switching unit, an imaging device (104), and a communication link. The switching unit is interfaced with the communication link and adapted to selectively operating the loading system to transfer commodity (28) from at least one storage bin (22) of the loading facility and into a transport bin (34) of a vehicle (32) being loaded. The imaging device (104) is interfaced with the communication link and positionable to provide a visual feed of the interior of the transport bin (34) during loading. A user interface device is accessible from within the cab (38) of the vehicle (32) being loaded such that the communication link interfaces the user interface device to the control device. The user interface device has at least one switch operable to control the switching unit to thereby initiate and terminate the loading of commodity (28) into the transport bin (34) of the vehicle (32) being loaded. The user interface device has a display for displaying within the cab (38) of the vehicle (32) being loaded, the visual feed of the interior of the transport bin (34) during loading of commodity.
Patent NZ-594953-A (NZ)
Title: Energy absorbing and displacing structure for athletic protective equipment
Inventor: KAMRADT BRIAN
IPC: A41D13/08
Filed: 2010-02-02
Abstract: An energy absorbing and displacing structure for athletic protective equipment, such as an athletic shin-guard, is provided using a flexible web-shaped body to hold a rigid band-shaped member in place. The inner rigid band-shaped member follows the contour of the desired area to protect. The outer flexible web-shaped body is made of a softer rubber like material and works as a locator and supporter keeping the inner, rigid band-shaped member, in proper location.
Patent NZ-598380-A (NZ)
Title: Photosensitizing compositions
Inventor: KLAVENESS JO
IPC: C12N15/87
Filed: 2010-08-16
Abstract: 598380 Disclosed are salts of amphiphilic photosensitizing agents which is formed from an amino alcohol. The amphiphilic photosensitizing agent may be TPCS2a(Amphinex), TPPS2a, or Porfimer(Photofrin®). The amino alcohol may be selected from monoethanolamine, di-ethanolamine, tri-ethanolamine and 2-amino-2-(hydroxymethyl) propane-1,3-diol; a cyclic amino alcohol, e.g. selected from 4-(2-hydroxyethyl)-morpholine and 1-(2-hydroxyethyl)-pyrrolidine; or an amino sugar, e.g. selected from glucamine and N-methylglucamine (meglumine). The use of the salts in photochemical internalisation(PCI) is also disclosed for introducing a drug molecule into the cytosol of a cell in a patient, said method comprising the following steps: (a) contacting said cell with the pharmaceutically acceptable salt of an amphiphilic photosensitizing agent; (b) contacting said cell with said drug molecule; and (c) irradiating said cell with light of a wavelength effective to activate thephotosensitizing agent. Compositions and kits comprising the salts are also disclosed.
Patent NZ-600041-A (NZ)
Title: Wind turbine with at least two generaors coupled via a differential gear unit
Inventor: KROEGER UWE
IPC: F03D7/02
Filed: 2010-10-20
Abstract: 600041 Disclosed is a wind power installation with at least one wind turbine (1) and a current generator device. The current generator device has at least two generators (2, 3) which are coupled to one another via at least one differential gear unit (4). Rotors (5, 6) of the generators (2, 3) are in each case connected to an axial gear (7, 8) of the differential gear unit (4). The wind turbine (1) is arranged on a balancing gear (9) of the differential gear unit (4), and the stators (10, 11) of the generators (2, 3) are connected to one another to form an abutment on which the differential carrier (13) of the differential gear unit (4) is accommodated such that it can rotate.
Patent NZ-600668-A (NZ)
Title: Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
Inventor: MULLER GEORGE W
IPC: A61K31/4035
Filed: 2008-03-27
Abstract: ABSTRACT - 600668 The disclosure relates to solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione represented by structural formula (I), compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. Particularly disclosed is a solid form comprising the enantiomerically pure compound of formula (I) having an X-ray powder diffraction pattern comprising peaks at about 8.1, 15.2, 17.4, 23.6 and 25.1 degrees 2theta. These solid forms are suitable for treating and/or preventing disorders ameliorated by the reduction of levels of TNF-( or the inhibition of PDE4 and are are used for treating a disease or disorder selected from psoriasis; psoriatic arthritis; rheumatoid arthritis; chronic cutaneous sarcoid; giant cell arteritis; Parkinson's Disease; prurigo nodularis; lichen planus; complex apthosis; Behcet's Disease; lupus; hepatitis; uveitis; Sjogren's Disease; depression; interstitial cystitis; vulvodynia; prostatitis; osteoarthritis; diffuse large B cell lymphoma; polymysoitis; dermatomyositis; inclusiuon body myositis; erosive osteoarthritis; interstitial cystitis; hepatitis; endometriosis; radiculopathy; and pyoderma gangrenosum, and are also used for treating a disease or disorder is selected from HIV; hepatitis; adult respiratory distress syndrome; bone resorption diseases; chronic obstructive pulmonary diseases; chronic pulmonary inflammatory diseases; dermatitis; inflammatory skin disease, atopic dermatitis, cystic fibrosis; septic shock; sepsis; endotoxic shock; hemodynamic shock; sepsis syndrome; post ischemic reperfusion injury; meningitis; psoriasis; fibrotic disease; cachexia; graft rejection including graft versus host disease; auto immune disease; rheumatoid spondylitis; arthritic conditions, such as rheumatoid arthritis and osteoarthritis; osteoporosis; Crohn's disease; ulcerative colitis; inflammatory bowel disease; multiple sclerosis; systemic lupus erythrematosus; erythema nodosum leprosum in leprosy; radiation damage; asthma; hyperoxic alveolar injury; and cancer.
Patent NZ-606771-A (NZ)
Title: Protective holder for a padlock, and assemblies incorporating same
Inventor: DAVID ALAN FLORRIMELL
IPC: E05B67/38
Filed: 2013-02-07
Abstract: Protective holder for a padlock (lockbox). The shank of a padlock is hung over a retainer within the confines of a lock box (1). The padlock can be unlocked with the key from the bottom via access through the open bottom of the lockbox. The hook portion (63) of a catch (60) on the closure (32) to be locked enters the space defined by the shank of the padlock via an aperture in the lockbox when the padlock is open. When the padlock is closed by forcing the body of the padlock onto the shank form below, the hook portion is captured behind the body of the padlock to lock the closure.
Patent NZ-608316-A (NZ)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: G01N33/573
Filed: 2011-10-06
Abstract: Disclosed is a method for evaluating renal status in a subject, comprising: - performing one or more assays configured to detect at least Follistatin in a body fluid sample previously obtained from the subject; and - correlating the assay result(s) to the renal status of the subject.
Patent NZ-609589-A (NZ)
Title: System for operating a lottery
Inventor: PIPER JAMES WILLIAM
IPC: G07C15/00
Filed: 2012-08-15
Abstract: A computer system for recording entries and determining one or more winners of a lottery or a lottery game, in which participants are invited to select at least one symbol from a defined available range of symbols, between one and n, to register their selection with the computer system id disclosed. The computer system is capable of recording at least the symbol or symbols selected in or on entries and the originating lottery organization, country or area for each entry, and optionally the identity or contact details of the participant and the date and time of the entry, including how many times each symbol in the available symbol range was selected in or on each of the entries in the game and to provide a ranking list of the number of times each symbol was selected, the ranking of each symbol in the ranking list being determined by the number of times each symbol is selected in or on entries. The lottery has at least two phases, the first phase running until a defined time has expired whereupon at least one of the n symbols is selected and the selection is made by selecting at least one of the symbols in the ranking list based on selection criteria pre-determined by reference to the rankings of the symbols in the ranking list, to provide a number of entries, at least some of whom have selected one of the n symbols selected, and moving the selected entries to a second phase of the lottery, which second phase comprises an elimination process to determine one or more winners from those entries that were selected to move from the first phase to the second phase. The winner or winners in the second phase is the final entry or entries at the end of a pre-determined elimination process, and optionally where the computer system can also record one or more winners from each originating lottery organization, country or area in the first phase and/or second phase.
Patent NZ-616628-A (NZ)
Title: Apparatus for marking histology embedding cassettes
Inventor: CINTI MARIO
IPC: G01N35/00
Filed: 2012-05-24
Abstract: Disclosed is a marking apparatus (1) for marking histology embedding cassettes (10). The marking apparatus (1) is comprised of a marking device (2) suitable for marking plastic surfaces presented before it; a gripping means (31, 32) able to alternatively grip and release an embedding cassette (10); and a movement organ (5, 6) to rotate the gripping means (31, 32) with respect to at least a first rotation axis (R) and at least a second rotation axis (Q). The first rotation axis (R) is arranged with respect to the gripping means (31, 32) in such a way that, in use, the first rotation axis is situated in an ideal plane that is parallel to and interposed between the ideal planes in which perpendicular surfaces of a cassette (10), gripped by the gripping means (31, 32), are located. Upon rotation of the gripping means (31, 32) with respect to the first axis (R), the first and the second perpendicular surfaces can alternately be located in front of the marking device (2). The second rotation axis (Q) is perpendicular to the first rotation axis (R) and is arranged with respect to the gripping means (31, 32) in such a way that, in use, upon rotation of the gripping means (31, 32), with respect to the second axis (Q), an oblique surface of the gripped cassette (10) can be in front of the marking device (2).
Patent NZ-702224-A (NZ)
Title: Dimensionally stable geopolymer compositions and method
Inventor: DUBEY ASHISH
IPC: C04B111/72
Filed: 2013-04-19
Abstract: A method for making geopolymer cementitious binder compositions for cementitious products such as concrete, precast construction elements and panels, mortar and repair materials, and the like is disclosed. The geopolymer cementitious compositions of some embodiments are made by mixing a synergistic mixture of thermally activated aluminosilicate mineral, calcium aluminate cement, a calcium sulfate and a chemical activator with water
Patent NZ-722031-A (NZ)
Title: Genetic markers and uses therefor
Inventor: MATHEW DOUGLAS LITTLEJOHN
IPC: C12N15/12
Filed: 2013-10-25
Abstract: Disclosed is a method for determining whether it is more likely than not that an animal and/or its offspring will have an increased tolerance to heat, the method comprising determining whether or not an animal, embryo or gamete includes one or more variation in PRLR or the PRLR gene or a genetic marker in linkage disequilibrium therewith, wherein where the variation is associated with resistance to ticks.
Patent NZ-724646-A (NZ)
Title: Apparatus for pari-mutuel racing game with finish order betting
Inventor: ALDERUCCI DEAN P
IPC: G07F17/32
Filed: 2007-10-08
Abstract: An apparatus comprises at least one processor; and at least one tangible memory device having software stored thereon that when executed by the at least one processor directs the at least one processor to: receive via a communications network a plurality of inputs comprising bets that a plurality of participants will win a race; determine, based at least on the plurality of received bets and a weight measurement of each participant, payoff odds for each of the plurality of participants, in which the participant with a lowest payoff odds is a favoured participant to win the race, the participant with a next lowest payoff odds is a next favoured participant to win the race, and the participant with a highest payoff odds is a least favoured participant to win the race; determine, based at least on the payoff odds, a potential order in which all participants in the race might finish the race, in which the potential order includes the favoured participant finishing the race first, the next favoured participant finishing the race second, and the least favoured participant finishing the race last; receive a reverse-order-bet that all participants in the race will finish the race in an order that is a reverse order of the determined potential order, in which the reverse order includes the least favoured participant finishing the race first, the next favoured participant finishing the race second to last, and the favoured participant finishing the race last; based on results of the race received via a communications network, determine an actual order in which the plurality of participants finished the race; based on the actual order in which the plurality of participants finished the race, determine whether the reverse order transpired; and determine a payment amount based on whether the reverse order transpired.
Patent NZ-725617-A (NZ)
Title: Block adaptive color-space conversion coding
Inventor: SOLE ROJALS JOEL
IPC: H04N19/117
Filed: 2015-06-04
Abstract: A video coder decodes a coding unit (CU) of video data. In decoding the video data, the video coder determines that the CU was encoded using the color space conversion. The video coder determines the initial quantization parameter (QP), determines the final QP that is equal to a sum of the initial QP and a QP offset, and inverse quantizes, based on the final QP, a coefficient block, then reconstructs the CU based on the inverse quantized coefficient blocks. The method also determines a boundary strength of a luma edge of the decoded video block, wherein the boundary strength of the luma edge is dependent on the final QP for the luma component; and based on the boundary strength of the luma edge not meeting a first threshold, performing a deblocking filtering process on the luma edge.
Patent NZ-727365-A (NZ)
Title: Methods and system for creating focal planes in virtual and augmented reality
Inventor: CHENG HUI-CHUAN
IPC: G02B15/20
Filed: 2015-05-29
Abstract: Configurations are disclosed for presenting virtual reality and augmented reality experiences to users. The system may comprise a spatial light modulator operatively coupled to an image source for projecting light associated with one or more frames of image data, and a variable focus element (VFE) for varying a focus of the projected light such that a first frame of image data is focused at a first depth plane, and a second frame of image data is focused at a second depth plane, and wherein a distance between the first depth plane and the second depth plane is fixed.
Patent NZ-737945-A (NZ)
Title: Orodispersible dosage unit containing an estetrol component
Inventor: JASPART SÉVERINE FRANCINE ISABELLE
IPC: A61K9/00
Filed: 2016-06-17
Abstract: The invention provides an orodispersible solid pharmaceutical dosage unit having a weight between 30 and 1,000 mg, said dosage unit consisting of: 0.1-25 wt.% of estetrol particles containing at least 80 wt.% of an estetrol component selected from estetrol, estetrol esters and combinations thereof; and 75-99.9 wt.% of one or more pharmaceutically acceptable ingredients; the solid dosage unit comprising at least 100 μg of the estetrol component; and wherein the solid dosage unit can be obtained by a process comprising wet granulation of estetrol particles having a volume weighted average particle size of 2 μm to 50 μm. The solid dosage unit is easy to manufacture and perfectly suited for sublingual, buccal or sublabial administration.
Patent NZ-746608-A (NZ)
Title: Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof
Inventor: CALIENNI JOHN VINCENT
IPC: C07D487/04
Filed: 2011-11-09
Abstract: Disclosed is crystalline ribociclib succinate (N,N-dimethyl-7-cyclopentyl-2-(5-(piperazin-1-yl)-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-carboxamide mono-succinic acid salt) and intermediates for the synthesis of ribociclib. Also disclosed is a pharmaceutical composition comprising: (a) a therapeutically effective amount of the salt and at least one pharmaceutically acceptable carrier, diluent, vehicle or excipient for the treatment of diseases such as cancers which responds to inhibition of cyclin dependent kinase activity.
Patent NZ-750504-A (NZ)
Title: Antimicrobial Compositions and Related Methods of Use
Inventor: GANDHI NIRANJAN
IPC: A01N37/02
Filed: 2014-03-17
Abstract: Articles and antimicrobial compositions comprising propanoic acid and components selected from a C4-C6 acid salt, a C2-C5 acid ester, and a C2-C8 aldehyde, wherein the propanoic acid is present at a ratio of at least 7:2 with respect to each of the other components of the composition, and combinations thereof, and related methods of use to effect antimicrobial activity. Such as agricultural, industrial, building, pharmaceutical, personal care and/or animal care products and applications.
Patent NZ-757796-A (NZ)
Title: Electrical grounding systems
Inventor: LABARGE THOMAS EVAN
IPC: H01R4/66
Filed: 2018-02-22
Abstract: An electrical grounding system can include an electrically conductive column configured for communication with a fault current source and a carbon fiber layer in conductive relationship with at least a portion of the electrically conductive column. The system can also include a salt replenishment tube configured for attachment to a ground member, the salt replenishment tube having a tube wall defining a weep hole. The system can further include electrolytic fill disposed within a column chamber at least partially-defined by the electrically-conductive column, the electrolytic fill comprising a material configured to conduct at least a portion of any fault current received by the ground member radially outwardly from the ground member. The system can further include a bus bar comprising electrically-interconnected bus bar connectors, wherein the bus bar electrically communicates with the electrically conductive column and with the fault current source.
Patent NZ-766841-A (NZ)
Title: Preparation method of 4d chitosan-based thermosensitive hydrogel
Inventor: DONG YANHAN
IPC: A61L31/06
Filed: 2020-08-10
Abstract: The present invention belongs to the technical field of medical material production and preparation, and relates to a preparation method of a 4D chitosan-based thermosensitive hydrogel. First, chitosan is dissolved in acetic acid solution; a chitosan-based thermosensitive hydrogel is printed by a 4D bioprinter and lyophilized after solvent extraction, to obtain lyophilized chitosan; subsequently, aqueous β-sodium glycerophosphate solution is prepared with ultrapure water and β-sodium glycerophosphate, and then aqueous carboxymethyl chitosan solution is prepared with ultrapure water and aqueous β-sodium glycerophosphate solution are charged into and mixed well with aqueous carboxymethyl chitosan solution to prepare a mixture; finally, the lyophilized chitosan is crosslinked with the mixture to obtain the 4D chitosan-based thermosensitive hydrogel. With scientific and reliable principles thereof, the present invention solves a problem that conventional thermosensitive hydrogels have uneven pore sizes, and improves the entrapment efficiency and ability of limbal stem cells; the present invention has important theoretical significance and broad application prospects in the field of corneal wound healing, providing help for patients who require repair of corneal alkali burns in clinical medicine.