baber/WOPTO huggingface dataset:
Patent CA-2457928-A1 (CA)
Inventor: SCHREUDER JAMES D
IPC: H04L12/56
Filed: 2002-09-06
Abstract: A system for discovering a topology of a distributed processing network that includes a first topology Management Information Base discovery agent (308) configured to contact a first set of routers to obtain a first type of information stored in each router in the first set of routers; a second topology Open Shortest Path First discovery agent (312) and/or (316) configured to contact a second set of routers to obtain a second type of information stored in each router in the second set of routers, and a phase controller (304) configured to select between the first (308) and second (312) and/ or (316) topology discovery agents. The first and second sets of routers are different, and the first and second types of information are different. In one configuration, the first type of information is defined by a network management protocol, and the second type of information is defined by a routing protocol.
Patent CA-2458035-A1 (CA)
Title: Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them
Inventor: BIZZARRI CINZIA
IPC: A61P29/00
Filed: 2002-09-25
Abstract: (R)-Enantiomers of quaternary ammonium salts of general formula (I) are described: (I) where R, R1, R2, R3, X and Z are as defined in the descriptio n. The process for their preparation and pharmaceutical preparations thereof ar e also described. The quaternary salts of the invention are useful in the inhibition of chemotaxis of neutrophils and monocytes induced by the fractio n C5a of the complement and are used in the treatment of psoriasis, pemphigus and pemphigoid, rheumatoid arthritis, intestinal chronic inflammatory pathologies including ulcerative colitis, acute respiratory distress syndrom e, idiopathic fibrosis, cystic fibrosis, chronic obstructive pulmonary disease and glomerulonephritis. The compounds of the invention are advantageously us ed in the prevention and the treatment of injury caused by ischemia and reperfusion.
Patent CA-2462879-A1 (CA)
Title: Immunoconjugates for the treatment of tumours
Inventor: CORTI ANGELO
IPC: A61K47/48
Filed: 2003-04-30
Abstract: A pharmaceutical composition comprising a conjugate of a cytokine and a tumor targeting moiety (TTM) and a pharmaceutically acceptable excipient, wherein the cytokine is present in an amount which does not induce a negative feedback mechanism.
Patent CA-2463482-A1 (CA)
Title: Microbes a mutation d'attenuation renfermant un terminateur de transcription
Inventor: TINGE STEVEN A
IPC: C12N15/74
Filed: 2001-10-11
Abstract: L'invention concerne des compositions comprenant un microbe à mutation d'atténuation renfermant un terminateur de transcription recombinant inséré dans un gène chromosomique. Ces compositions peuvent être utilisées comme vaccins ou véhicules destinés à l'administration d'une protéine souhaitée à un individu. L'invention concerne en outre des méthodes d'immunisation d'un individu et des méthodes d'administration d'un produit génétique souhaité à un individu. Ces méthodes se basent sur l'administration de ces compositions.
Patent CA-2463620-A1 (CA)
Title: Auto-relieving pressure modulating valve
Inventor: ROYLE STEPHEN DALE
IPC: F16K31/06
Filed: 2002-10-11
Abstract: An auto-relieving pressure modulating valve (10) includes a spool (42), a solenoid (28) that shifts the spool in an energized direction (36'), and a spring arrangement (50). The spring arrangement functions to shift the spool from a relieving position to a neutral position, in the energized direction, without energizing the solenoid.
Patent CA-2464019-A1 (CA)
Title: Modular freeze branding device
Inventor: ALLARD DAVID P
IPC: A01K11/00
Filed: 2004-04-08
Abstract: A disclosed modular freeze branding device includes a frame and a number of character assemblies that are configured to be supported by the frame. Each assembly includes a substrate and a section of refrigerant conduit that is coupled to the substrate. The section of conduit has one or more thermally conductive segments arranged along a first side of the substrate to form the shape of a character. Variations and methods are also disclosed.
Patent CA-2464281-A1 (CA)
Inventor: INKPEN JOHN THOMAS
IPC: B63B35/00
Filed: 2004-04-14
Abstract: The present invention provides a kayak splash skirt with a transparent and waterproof map viewing pouch. The splash skirt is made of a water-resistant material, and comprises a skirt section with an opening formed therein for receiving a kayaker, dimensions sufficient to cover a cockpit opening of a kayak, an outer perimeter adapted to fit around coaming of the kayak cockpit in a water-tight manner, and which comprises a re-sealable, water-proof pouch on an upper surface thereof. The splash skirt also comprises a tunnel section which is adapted to fit around the torso of the kayaker in a water-tight manner, and which has an end sealingly connected to the opening of the skirt section. The pouch on the upper surface of the skirt section comprises a substantially transparent panel which permits map viewing while kayaking. This allows the kayaker to continue paddling while reading the map, maintains a close reading distance between the kayaker and the map, and provides a space for storage of other items.
Patent CA-2465006-A1 (CA)
Inventor: LOVEROCK DAVID
IPC: A63C19/08
Filed: 2004-04-21
Abstract: An ice painting device is provided for use with a source of paint for painting an ice surface. The source of paint includes a source outlet and a closeable valve for selectively closing a flow of paint from the source outlet. The painting device includes a wand for holding by an operator. The painting device further includes a conduit system associated with the wand for transporting the paint. The conduit system defines a passage having a passage inlet and a passage outlet. The passage inlet is fluidically connectable to the source outlet. The conduit system is configured to provide fluid flow characteristics selected so that when the valve is closed, paint is substantially prevented from flowing through the passage outlet. The conduit system is configured to have fluid flow characteristics that are selected so that when the valve is closed paint is substantially prevented from flowing through the passage outlet. The painting device further includes a pad that is positionable immediately downstream from the passage outlet. The pad is configured to receive paint from the passage outlet. The pad has an ice contact face for distributing paint onto the ice surface.
Patent CA-2466632-A1 (CA)
Inventor: CHEN GUOHUA
IPC: A61K47/38
Filed: 2002-11-14
Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, an aromatic alcohol having miscibility in water of le ss than or equal to 7 wt.% at 25~C, in an amount effective to plasticize the polymer and form a gel therewith, and a beneficial agent. The composition ma y additionally contain an ester of an aromatic acid, or an aromatic ketone. Th e compositions are readily implanted beneath a patient's body surface by injection, as the aromatic alcohol not only facilitates solubilization of th e polymer, but also acts as a thixotropic agent, substantially increasing the shear thinning behavior of the composition.
Patent CA-2467274-A1 (CA)
Title: Segmented foundation installation apparatus and method of installation therefor
Inventor: REINERT GARY
IPC: E02D27/42
Filed: 2002-11-14
Abstract: Novel anchors and foundations in customized lengths and installation method are less expensive, easier to hand and assemble in the field to match any required length. Vertical segmented support and media consolidation plates swingably mounted about pivot points vertical support means incorporate media-facing surfaces swingable outwardly from the into surrounding media. Varying segmented lengths form segmented vertical support means. Novel apparatus and method provide for centering collar (113), an anchor positioning means at level force pivoting plates (194), and pivoting plates (194) positioned 40-50 degrees from vertical. A frusto-cone 197 dx equal to a predetermined distance of one-half inch forms gap (204). The novel method installs a anchor and foundation device in the earth by preparing a hole in the earth, lowering into the hole a segmented anchor or foundation device having swingable media facing plates, and applying force to swing the plates outwardly into the surrounding media.
Patent CA-2468682-A1 (CA)
Inventor: AGLI WILLIAM A
IPC: C23C14/50
Filed: 2004-05-27
Abstract: A fixture locator comprising a fixture base comprising a first receptive chamber extending along a base centerline comprising a first receptive surface; and two base wedge slots extending into the fixture base and intersecting the first receptive surface; a machine tool mount, comprising a first mating member extending along a mount centerline comprising an outer surface adapted to fit within the first receptive chamber such that the mount centerline is congruent with the base centerline, and two mount wedge slots extending into the machine tool mount a dual wedge which comprises a first wedge prong and a second wedge prong each comprising a first and a second end symmetrically disposed about a wedge centerline, a wedge bridge adapted to connect the first ends of the first and second wedge prongs, and a fastening member adapted to removably fasten the second ends of the first and second wedge prongs wherein each of the first and second wedge prongs are adapted to extend in contact with one of the base wedge slots and the mount wedge slots.
Patent CA-2468983-A1 (CA)
Title: Consolidated body fluid testing device and method
Inventor: HAFELLNER REINHARD
IPC: A61B5/15
Filed: 2002-12-06
Abstract: A body fluid testing device (10) includes a body member (12) and a tissue penetrator (50) carried by the body member (12). A test strip holder (94) is carried by the body member (12), and a test strip (98) is carried by the tes t strip holder (104). The test strip (98) is capable of receiving a body fluid thereon and processing the body fluid into a form suitable for yielding test results relating to the content of the body fluid.
Patent CA-2471868-A1 (CA)
Inventor: ROSSI EDMUND
IPC: A61K48/00
Filed: 2002-12-26
Abstract: This invention relates to multi-specific, multivalent binding proteins and methods of generating these agents from VH and VL domains. The binding protein has three or more binding sites where at least one binding site binds with a hapten moiety and at least two sites bind with target antigens. The present invention further relates to bispecific, trivalent heterodimers that have at least one binding site with affinity towards molecules containing a histamine-succinyl-glycyl (HSG) moiety and at least two binding sites with affinity towards carcinoembryonic antigen (CEA), and to trispecific, trivalent heterodimers that have at least one binding site with affinity towards molecules containing a HSG moiety, at least one binding sites with affinity towards CEA, and at least one binding site having affinity towards a metal-chelate complex indium-DTPA. Moreover, this invention relates to recombinant vectors useful for the expression of these functional heterodimers in a suitable host.
Patent CA-2472135-A1 (CA)
Inventor: KRAKOWIAK WALTER
IPC: C09D127/18
Filed: 2002-03-13
Abstract: A dispersion of non-melt-processible fluoropolymer particles having an SSG o f less than about 2.225 in aqueous medium. The fluoropolymer particles compris e a core of high molecular weight polytetrafluoroethylene having an average me lt creep viscosity greater than about 1.5 x 1010 Pa.bullet.s and a shell of low er molecular weight polytetrafluoroethylene or modified polytetrafluoroethylene . The shell has an average melt creep viscosity greater than about 9 x 109 Pa.bullet.s and comprises about 5 to about 30% by weight of the particles. T he fluoropolymer in the dispersion of the invention is fibrillating.
Patent CA-2473224-A1 (CA)
Title: Process for the preparation of urea
Inventor: MEESSEN JOZEF HUBERT
IPC: C07C273/04
Filed: 2002-12-30
Abstract: Process for the preparation of urea from carbon dioxide and ammonia by means of a urea stripping process, comprising a high-pressure stripper and a high- pressure condenser, whereby a urea synthesis solution is formed, and wherein the stream condensate that forms during high-pressure stripping of the urea synthesis solution is utilized for medium-pressure decomposition of the ammonium carbamate in the urea synthesis solution, characterized in that a combination of the steam condensate and steam A, which forms in the high- pressure condenser, is used for medium-pressure decomposition, with the high- pressure condenser being a submerged condenser. The invention also relates to a process for improving a urea plant comprising a thermal stripping process.
Patent CA-2476434-A1 (CA)
Inventor: RICHON VICTORIA M
IPC: A61P21/00
Filed: 2003-02-14
Abstract: L'invention concerne une nouvelle méthode de traitement et/ou de prévention des maladies et d'états pathologiques médiés par la thiorédoxine (TRX), ladite méthode consistant à administrer à un sujet, nécessitant ledit traitement, une quantité thérapeutiquement efficace d'un inhibiteur de l'histone-déacétylase (HDAC) ou un des sels pharmaceutiquement acceptable ou un de ses hydrates. Ledit inhibiteur de HDAC peut transformer l'expression d'une protéine de liaison de la thiorédoxine (par exemple TBP-2), qui à son tour peut conduire à une interaction transformée de la liaison cellulaire de TRX/protéine de liaison de la thiorédoxine, en faisant augmenter ou diminuer le niveau ou l'activité de la TRX cellulaire, par exemple le niveau d'expression ou l'activité de réduction de la TRX. L'invention concerne également l'utilisation des inhibiteurs de HDAC dans une méthode de prévention et/ou de traitement d'une pluralité de maladies et d'états pathologiques médiés par la thiorédoxine (TRX), tels que des maladies inflammatoires, des maladies allergiques, des maladies auto-immunes, des maladies associées à un stress oxydatif ou des maladies caractérisées par une hyperprolifération cellulaire.
Patent CA-2476896-A1 (CA)
Inventor: IVANOVA SVETLANA M
IPC: A61P17/02
Filed: 2003-02-26
Abstract: L'invention concerne des procédés d'inhibition de la libération d'une cytokine pro-inflammatoire ou de l'inflammation chez un vertébré. Ces procédés consistent à activer un récepteur muscarinique cérébral du vertébré, ou à stimuler directement le mécanisme d'action d'un nerf vague dans son cerveau. L'invention concerne par ailleurs des procédés de conditionnement d'un vertébré qui consistent à inhiber la libération d'une cytokine pro-inflammatoire ou réduire l'inflammation chez le vertébré par l'application d'un stimulus sensoriel. Ces méthodes consistent à : (a) activer un récepteur muscarinique cérébral ou stimuler directement le mécanisme d'action du nerf vague dans le cerveau du vertébré, et appliquer un stimulus sensoriel au vertébré dans un laps de temps suffisant pour créer un lien entre le stimulus et l'activation du récepteur muscarinique cérébral; et (b) répéter l'opération (a) à des durées et des intervalles de temps suffisants pour renforcer suffisamment le lien en question et réduire ainsi l'inflammation par la seule application d'un stimulus sensoriel.
Patent CA-2482348-A1 (CA)
Inventor: GRIGORIEFF MELISSA
IPC: A61P25/28
Filed: 2003-05-16
Abstract: La présente invention concerne une méthode de traitement d'un état pathologique ou d'une maladie sélectionnés dans le groupe comprenant l'hypertension, le dysfonctionnement ventriculaire gauche et la cardiomyopathie hypertrophique, la myopathie cardiaque diabétique, les arythmies supraventriculaire et ventriculaire, la fibrillation auriculaire, le flutter auriculaire, le remodelage vasculaire préjudiciable, l'infarctus du myocarde et ses séquelles, l'athérosclérose, l'angine (instable ou stable), l'insuffisance rénale (diabétique et non diabétique), l'insuffisance cardiaque, l'angine de poitrine, le diabète, l'aldostéronisme secondaire, l'hypertension pulmonaire primaire et secondaire, les états d'insuffisance rénale, tels que la néphropathie diabétique, la glomérulonéphrite, la sclérodermie, la sclérose glomérulaire, la protéinurie de la maladie rénale primaire, ainsi que l'hypertension vasculaire rénale, la rétinopathie diabétique, le traitement d'autres troubles vasculaires, tels que la migraine, la maladie vasculaire périphérique, la maladie de Raynaud, l'hyperplasie luminale, le dysfonctionnement endothélial, le dysfonctionnement cognitif (tel que la maladie d'Alzheimer), le glaucome et l'accident vasculaire cérébral. Ladite méthode consiste à administrer, à un mammifère nécessitant un tel traitement, une quantité thérapeutiquement efficace d'une combinaison comprenant (i) un inhibiteur ACE, (ii) un inhibiteur calcique (CCB), et (iii) un diurétique.
Patent CA-2485491-A1 (CA)
Inventor: HUQ ABU
IPC: A61P31/04
Filed: 2003-05-19
Abstract: Cette invention se rapporte à de nouvelles formulations associant un médicament anti-inflammatoire non stéréoïdien (NSAID) tel que flunixine, à un antibiotique dérivé de chloramphéniocol ou de thiamphénicol fluoré, tel que florfénicol. Cette invention concerne également des procédés d'utilisation de ces formulations dans le traitement et la prévention des maladies infectieuses chez le bovin et chez le porc, telles que la grippe bovine et la grippe porcine.
Patent CA-2487799-A1 (CA)
Inventor: SIKLOSI TIBOR
IPC: B60S1/38
Filed: 2003-05-30
Abstract: A wiper assembly (11) having a wiper frame (13) and a wiper boot (17). The wiper boot includes an upper wall (31) integrally connected between two side walls (33). A lower leg (35) is integrally connected to each side wall at an end opposite that of the upper wall. Each lower leg (35) runs transversely a nd inwardly from the side walls (33), the lower legs (35) integrally connecting to a u-shaped wall (36). The upper wall, the side walls, the lower legs, and the u-shaped wall define a cavity (37) that receives the wiper frame. The wiper boot is made from silicone elastomer that preferably includes approximately 30 to 60 weight percent of polyvinylmethylsiloxane, approximately 15 to 40 weight percent of iller, approximately 0.1 to 10 weig ht percent of pigment, and approximately 0.1 to 10 weight percent of catalyst.< /SDOAB>
Patent CA-2488134-A1 (CA)
Title: Emetteur d'ultrasons resistant a la corrosion
Inventor: GUNNERMAN RUDOLF W
IPC: B06B3/00
Filed: 2003-11-26
Abstract: On donne à des émetteurs d'ultrasons (11) en titane une résistance à la corrosion dans des milieux aqueux en les dotant d'une surface terminale (19, 24) en argent (18, 23) constituant une partie ou l'intégralité de ladite surface.
Patent CA-2488629-A1 (CA)
Title: Cancer-linked gene as target for chemotherapy
Inventor: RICK JENNIFER A
IPC: C12Q1/68
Filed: 2003-06-05
Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclose d along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed ar e antibodies that react with the disclosed polypeptides and methods of using t he antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.< /SDOAB>
Patent CA-2491327-A1 (CA)
Inventor: ANDRYS ROMAN
IPC: G09F19/00
Filed: 2004-12-30
Abstract: A miniature sports logo display is disclosed. It allows a miniature sports team uniform, together with the team logo, the team color, a player's name and a player's number to be publicly displayed from a motor vehicle window. The invention is comprised of a miniature sports uniform having the described features and adapted to receive a miniature hanger, a miniature hanger inserted into the uniform for suspension of the uniform, and means, such as a suction cup, for securing the miniature hanger and uniform to a substantially vertical surface, attached to the hook of the miniature hanger. Optionally, the miniature sports uniform may be covered with a transparent cover.
Patent CA-2500121-A1 (CA)
Title: Lightweight cryogenic-compatible pressure vessels for vehicular fuel storage
Inventor: BERRY GENE
IPC: F17C3/08
Filed: 2003-09-11
Abstract: A lightweight, cryogenic-compatible pressure vessel for flexibly storing cryogenic liquid fuels or compressed gas fuels at cryogenic or ambient temperatures. The pressure vessel has an inner pressure container enclosing a fuel storage volume, an outer container surrounding the inner pressure container to form an evacuated space therebetween, and a thermal insulator surrounding the inner pressure container in the evacuated space to inhibit heat transfer. Additionally, vacuum loss from fuel permeation is substantially inhibited in the evacuated space by, for example, lining the container liner with a layer of fuel-impermeable material, capturing the permeated fuel in the evacuated space, or purging the permeated fuel from the evacuated space.
Patent CA-2500927-A1 (CA)
Title: Implantable cross-pin for anterior cruciate ligament repair
Inventor: MAY THOMAS C
IPC: A61B17/58
Filed: 2005-03-15
Abstract: A novel cross-pin for use in ACL reconstructive surgical procedures. The cross-pin has an elongated body having a distal tapered end. A guide wire opening in the distal end is in communication with a tunnel contained in the distal end.  There is a trough extending into the outer surface of the trough for receiving a guide wire. The trough is in communication with the tunnel.
Patent CA-2502640-A1 (CA)
Title: A process for the preparation of tolterodine and intermediates thereof
Inventor: CASTALDI GRAZIANO
IPC: C07D311/20
Filed: 2005-03-29
Abstract: A process for the preparation of 6-methyl-4-(R)-phenyl-chroman-2-one and 6-methyl-4-(S)-phenyl-chroman-2-one, intermediates for the synthesis of tolterodine and its (S) enantiomer, by reaction of 6-methyl-coumarin with phenylboronic acids, esters and derivatives thereof, in the presence of chiral catalysts.
Patent CA-2503871-A1 (CA)
Title: An immunogenic composition for generating an immune response against polio virus
Inventor: MAYERESSE YVES
IPC: A61P31/12
Filed: 2003-10-30
Abstract: The present invention relates to immunogenic compositions comprising a dried solid or highly viscous liquid formulation of inactivated polio virus (IPV) and a stabilising agent wherein the IPV retains its antigenicity and/or immunogenicity. Methods of producing a dried formulation of IPV which retain s its antigenicity/immunogenicity are described.
Patent CA-2505635-A1 (CA)
Title: Celecoxib prodrug
Inventor: EWING GARY D
IPC: C07D231/12
Filed: 2003-11-03
Abstract: N-[[4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-sulfonyl]propanamide and pharmaceutically acceptable salts thereof are useful prodrugs of the selective COX-2 inhibitory drug celecoxib, which can be administrated to a subject by any suitable route.
Patent CA-2506860-A1 (CA)
Inventor: WOODWARD JERRY A
IPC: F16B39/28
Filed: 2005-05-09
Abstract: Cette invention concerne un dispositif de retenue pour un connecteur boulonné fendu qui comprend une paroi continue qui délimite une ouverture et au moins une languette pliable s'étendant vers le haut à partir de la paroi ou d'un élément s'étendant entre les sections de paroi opposées. La paroi est conçue pour s'adapter à l'écrou sur un connecteur boulonné fendu dans l'ouverture et la languette, ou l'élément, est adaptée pour engager la fente dans le boulon fendu après la connexion de l'écrou au boulon fendu.