baber/WOPTO huggingface dataset:
Patent EP-3959230-A1 (EP)
Title: Cancer therapy by modifying neoantigen expression
Inventor: LA THANGUE NICHOLAS
IPC: C12N9/10
Filed: 2020-04-24
Abstract: This invention relates to methods, agents and compositions for regulating the neoantigen landscape of cancer cells, based on the realisation that intro n retention in a cancer cell can be manipulated. Agents that can modify retained intron neoantigen expression in cancer cells are described, and their use in drug discovery and therapy. One aspect provides an agent for use in a method of treating cancer by modifying the neoantigen profile of at least one cancer cell. The agent may typically be a protein arginine N-methyltransferase 5 (PRMT5) inhibitor, and/or may reduce methylation of an E2F protein, for example E2F1.
Patent EP-3952907-A1 (EP)
Inventor: DALLMEIER KAI
IPC: A61K39/12
Filed: 2020-04-10
Abstract: A polynucleotide comprising the sequence of a live, infectious, attenuated Zika - Japanese encephalitis (JEV) chimeric virus wherein the nucleotide sequence encoding the prME protein of said Zika virus is replaced by a nucleotide sequence encoding the prME protein of a Japanese encephalitis virus, so that said prME protein of said Japanese encephalitis virus is expressed.
Patent EP-3927796-A1 (EP)
Inventor: MEYKE RALF
IPC: C10N10/12
Filed: 2020-04-22
Abstract: A lubricating oil composition and method of lubricating an engine equipped with a diesel particulate filter using the lubricating oil composition. The lubricating oil composition may contain greater than 50 wt.% of a base oil of lubricating viscosity, an amount of one or more calcium-containing detergents to provide less than 1700 ppm calcium, an amount of one or more magnesium-containing detergents to provide less than 450 ppm magnesium, an amount of one or more molybdenum-containing compounds to provide less than 450 ppm molybdenum, from about 700 ppm to about 900 ppm of phosphorus, and a total sulfated ash content of no greater than 1.0 wt.%, all as measured by ASTM D874, based on the total weight of the lubricating oil composition; and a ratio, in ppm, of calcium from the one or more calcium-containing detergents to magnesium from the one or more magnesium-containing detergents of 1:1 or more.
Patent EP-3948568-A1 (EP)
Title: Messaging to enforce operation serialization for consistency of a distributed data structure
Inventor: LUCCO STEVEN EDWARD
IPC: G06F16/178
Filed: 2020-04-07
Abstract: Disclosed embodiments provide for collaborative access to a distributed data structure. Operations such as inserting, deleting, and annotating are performed by various clients participating in the collaboration. A serialization service enforcing a single order of these operations and ensures the operations and order are communicated to all of the clients participating in the collaboration. Once all clients have acknowledged particular operations, this information is also communicated to all of the clients, such that the clients may perform maintenance activities on the collaboration data structures. The result is a rolling collaboration window shared by all of the clients of the collaboration, with a bottom of the collaboration window defined by a lowest ordered operation not yet acknowledged by all clients of the collaboration, and a highest ordered operation as assigned by the serialization service.
Patent EP-4031820-A1 (EP)
Inventor: LIU YIJUN
IPC: F25J1/00
Filed: 2020-04-17
Abstract: A method and apparatus for producing liquefied natural gas (LNG) from a natural gas stream. Heavy hydrocarbons are removed from the natural gas stream in a separator to generate a bottom stream and a separated natural gas stream, which is used as a coolant in a heat exchanger to generate a pretreated natural gas stream. The pretreated natural gas stream is compressed and cooled to form a chilled pretreated natural gas stream, part of which forms a recycle stream to exchange heat with the separated natural gas stream in the heat exchanger, thereby generating a cooled recycle stream. The temperature and pressure of the cooled recycle stream are reduced. The cooled recycle stream is then separated into an overhead stream and a reflux stream, which is directed to the separator. The chilled pretreated gas stream is liquefied to form LNG.
Patent EP-4154384-A1 (EP)
Title: Systèmes électroniques de puissance du type optique sans fil hybride
Inventor: LUVISOTTO MICHELE
IPC: H02M1/092
Filed: 2020-05-18
Abstract: L'invention concerne un système électronique de puissance (PES) du type optique sans fil hybride. Le PES comprend un ensemble de N composants électroniques de puissance (PEC). Le PES comprend en outre un ensemble de Q premières unités d'émission-réception sans fil. Les PEC sont connectés fonctionnellement aux premières unités d'émission-réception sans fil sur un premier réseau de communication à fibre optique. Les premières unités d'émission-réception sans fil sont conçues pour se communiquer avec un dispositif de commande du PES sur un réseau de communication sans fil, afin de faciliter la communication de signaux entre le dispositif de commande et les PEC.
Patent EP-3966483-A1 (EP)
Inventor: AL OTAIBI ABDULAZIZ M
IPC: F16L41/02
Filed: 2020-05-07
Abstract: A method for depressurizing a pipe includes forming, by an ejector assembly, a seal between a first pipe and a second pipe fluidically coupled to the tee pipe fitting. The first pipe flows a first fluid at a first pressure, and the second pipe flows a second fluid at a second pressure lower than the first pressure. The ejector assembly includes a nozzle converging along a flow direction of the first fluid flowing in the first pipe, and a mixing chamber at an outlet of the nozzle, the mixing chamber comprising an outlet is in fluid communication with the second pipe. The method also includes flowing the first fluid from the first pipe into the ejector assembly through the nozzle so that the pressure of the first fluid decreases to a third pressure lower than the second pressure to draw the second fluid into the mixing chamber.
Patent EP-3973258-A1 (EP)
Title: Interferometereinrichtung und verfahren zum herstellen einer interferometereinrichtung
Inventor: SCHELLING CHRISTOPH
IPC: G01J3/26
Filed: 2020-05-15
Abstract: Die vorliegende Erfindung schafft eine Interferometereinrichtung (10) umfassend eine Interferometereinheit (1) mit einem Basissubstrat (2), einer Fabry-Perot-Einheit (FPI), und mit einer Detektoreinrichtung (3), und einem Gehäuse (G) welches eine Bodenplatte (BP) und eine Deckelstruktur (4) umfasst, wobei die Deckelstruktur (4) auf der Bodenplatte (BP) angeordnet ist und eine zweite Kavität (K2) zwischen Deckelstruktur (4) und Bodenplatte (BP) einschließt, wobei die Bodenplatte (BP) oder die Deckelstruktur (4) eine Öffnung (5) umfasst, welche von Seitenwänden (5a) umgeben ist, die sich zu einer Oberfläche der Bodenplatte (BP) oder der Deckelstruktur (4) senkrecht erstrecken; und wobei die Interferometereinheit (1) in der zweiten Kavität (K2) und in einer Lichteinfallsrichtung (L) durch die Öffnung (5) angeordnet ist, so dass die Interferometereinheit (1) mit der Fabry-Perot-Einheit (FPI) der Öffnung (5) zugewandt ist.
Patent EP-3981044-A1 (EP)
Inventor: BOUILLET AARON
IPC: H01Q1/38
Filed: 2020-06-05
Abstract: An antenna structure is described that includes a flexible substrate and at least two antenna elements being formed from conductive traces on a layer of the flexible substrate. The antenna structure also includes a plurality of conductive traces formed on the layer of the flexible substrate with a first subset being electrically coupled as a lead in to a first one of the antenna elements and a second subset of the plurality of conductive traces being electrically coupled as a lead in to a second one of the antenna elements, wherein the first subset and the second subset are separately coupled electrically to one connector after insertion of an edge of the flexible substrate into the connector. An apparatus is described that includes a case, an electronic assembly, including a printed circuit board and a support bracket, contained within the case. The apparatus further includes the antenna assembly as described herein.
Patent EP-4018267-A1 (EP)
Title: Refractive index modulation modification in a holographic grating
Inventor: LEIBOVICI MATTHIEU CHARLES RAOUL
IPC: G03H1/02
Filed: 2020-05-14
Abstract: Techniques disclosed herein relate to modifying refractive index modulation in a holographic optical element, such as a holographic grating. According to certain embodiments, a holographic optical element or apodized grating includes a polymer layer comprising a first region characterized by a first refractive index and a second region characterized by a second refractive index. The holographic optical element or apodized grating includes a plurality of nanoparticles dispersed in the polymer layer. The nanoparticles have a higher concentration in either the first region or the second region. In some embodiments, the nanoparticles may be configured to increase the refractive index modulation. In some embodiments, the nanoparticles may be configured to apodize the grating by decreasing the refractive index modulation proximate to sides of the grating. The refractive index may be modulated by applying a monomer reservoir buffer layer to the polymer layer, either before or after hologram fabrication.
Patent EP-4165453-A1 (EP)
Inventor: ASSALE MARCO
IPC: G02B6/42
Filed: 2020-06-10
Abstract: There is provided an interface module (200), comprising: an interface (208) for connection with a signal connector (250); a cage (206) for guiding the signal connector towards the interface; and a heat sink (202). The cage (206) comprises a cage portion (212) that is configured to move from a first position to a second position upon insertion of the signal connector (250) into the cage. In the first position, the cage portion is not in thermal contact with the heat sink; when in the second position, the cage portion is in thermal contact with the heat sink. The cage portion (212) comprises one or more apertures (218).
Patent EP-3980736-A1 (EP)
Title: Microbolometer having reduced pixel pitch
Inventor: BOUDOU NICOLAS
IPC: G01J5/08
Filed: 2020-06-05
Abstract: The present disclosure relates to a microbolometer comprising an array of pixels, each pixel comprising one or more detection cells, each detection cell comprising an absorption layer (530), wherein: the pitch of the detection cells in at least one direction in the plane of pixel array is between 5 and 11 µm; a pixel fill factor FF of the absorption layer (530) of the one or more detection cells in each pixel is in a range 0.10 to 0.50; and a sheet resistance Rs of the absorption layer (530) of each detection cell is between 16 and 189 ohm/sq.
Patent EP-3993654-A1 (EP)
Title: Inductive heater assembly with temperature sensor
Inventor: COURBAT JEROME CHRISTIAN
IPC: A24F40/465
Filed: 2020-07-02
Abstract: An inductive heater assembly (10) for an aerosol-generating device, the inductive heater assembly comprising: at least one inductor coil (12) configured to generate a varying magnetic field when a varying electric current flows through the at least one inductor coil; at least one susceptor (11) arranged to be penetrated by the varying magnetic field generated by the at least one inductor coil to heat the susceptor; at least one temperature sensor (13) arranged to determine a temperature of the at least one susceptor, wherein the at least one temperature sensor comprises a first resistive sensing element (41) and a second resistive sensing element (42), wherein the first resistive sensing element is connected to the second resistive sensing element and wherein the first resistive sensing element is positioned relative to the second resistive sensing element such that a current induced in the first resistive sensing element by the varying magnetic field opposes a current induced in the second resistive sensing element by the varying magnetic field.
Patent EP-3990774-A1 (EP)
Inventor: MESSING RALF
IPC: F03D1/06
Filed: 2020-06-25
Abstract: L'invention concerne un rotor (1, 106') pour une éolienne (100), une éolienne (100) ainsi qu'un procédé (300) pour l'augmentation du rendement d'un rotor (106) d'une éolienne (100). L'invention concerne en particulier un rotor (106) pour une éolienne (100) comprenant au moins une pale de rotor (1, 108), présentant un bord arrière (3) et un bord avant (2) de pale de rotors étendant entre la racine (4) et la pointe (5) sur une longueur (10) de pale de rotor, une profondeur de profilé se réglant entre le bord avant (2) et le bord arrière (3) de la pale de rotors, un angle de pas réglable, la pale de rotor (1, 108) présentant au moins un élément profilé (6) qui est disposé au niveau du bord arrière (3) de la pale de rotor ou dans une zone adjacente au bord arrière (3) de la pale de rotor pour agrandir la profondeur de profilé d'une contribution d'agrandissement (L1, L2, L3). Le rotor est caractérisé par une unité de commande (200) pour déterminer un angle de pas à régler, qui est conçu pour déterminer l'angle de pas qui se règle en fonction de la contribution d'agrandissement (L1, L2, L3).
Patent EP-3997297-A1 (EP)
Inventor: BENDEL THORSTEN
IPC: E05F15/616
Filed: 2020-06-16
Abstract: Gegenstand der Erfindung ist eine Aufstellvorrichtung (2) für ein Kraftfahrzeug (1), insbesondere eine Kraftfahrzeugtür (4), aufweisend einen elektrischen Antrieb (8) und ein Stellmittel (9), wobei das Stellmittel (9) mittels des Antriebs (8) verstellbar ist, und wobei die Kraftfahrzeugtür (4) mittels des Stellmittels (9) aufstellbar ist, wobei das Stellmittel (9) zumindest ein Anzeigemittel (12, 13, 14, 21) aufweist.
Patent EP-3913948-A1 (EP)
Inventor: WU YUMIN
IPC: H04W8/24
Filed: 2020-01-17
Abstract: Provided are a terminal capability negotiation method, a terminal device and a network-side device, the method comprising: when a terminal device has at least two terminal identifiers, reporting capability allocation information of the terminal device to a network-side device; wherein, the capability allocation information being used for indicating capabilities available to at least one of the terminal identifiers, the at least one terminal identifier comprising a terminal identifier of the at least two terminal identifiers.
Patent EP-4004755-A1 (EP)
Inventor: ROCHE OLIVIER
IPC: G06F15/78
Filed: 2020-07-23
Abstract: Système de traitement graphique de données (1), comprenant au moins cœur (C1-C4) de trai tement graphique de données comportant des moyens de mise en forme (2) aptes à interpréter sous forme graphique ou sous forme d'instructions les données échangées via une interface homme-machine, caractérisé en ce que lesdits moyens de mise en forme (2) sont répartis sur un ou plusieurs cœurs (C1-C4).
Patent EP-3986999-A1 (EP)
Inventor: LIU JIA
IPC: C12M1/12
Filed: 2020-06-23
Abstract: The present invention generally relates to nanoscale wires and nanoelectronics, which in some aspects may be embedded in biological structures, such as tissues, organoids, organs, organisms, and the like. For example, one aspect is generally directed to stretchable cell scaffolds, which may be connected to electrical circuits. In some cases, a biological structure may form around the scaffold and deform the cell scaffold as it forms, thereby causing the cell scaffold to become embedded within the biological structure. The scaffold may be connectable in certain embodiments to an external device, e.g., to determine a property of the cell scaffold (e.g., an electrical property), and/or to apply a stimulus (e.g., an electrical stimulus) to the biological structure. Other aspects of the invention are generally directed to methods of making or using such cell scaffolds, kits including such cell scaffolds, biological structures containing such cell scaffolds, or the like.
Patent EP-4168239-A1 (EP)
Inventor: LEE DARREL
IPC: B29K67/00
Filed: 2020-06-19
Abstract: Ways for controlling a level of a product in a container are provided that include engaging an exterior surface of the container containing the product at a first product level. A force is applied to the exterior surface of the container to cause the container to change from a first volume to a second volume. Cessation of the force results in the container containing the product at a second product level. The second product level can provide an accurate and reproducible final product level in the container.
Patent EP-4003249-A1 (EP)
Title: Dispositif et procédé pour le traitement de matière au moyen d'un rayonnement laser
Inventor: GUGGENMOS MARKUS
IPC: B23K26/0622
Filed: 2020-07-20
Abstract: La présente invention concerne un procédé pour le traitement de matière, en particulier pour modifier de la matière et/ou des propriétés de la matière, au moyen d'un rayonnement laser, ledit procédé comprenant les étapes suivantes, à savoir : a) la génération d'une pluralité d'impulsions laser (L) ; b) le guidage du point d'impact des impulsions laser (L) sur une pièce à traiter (100), en particulier la déviation des impulsions laser (L) et/ou le déplacement de la pièce à traiter (100), de telle sorte que les impulsions laser (L) soient guidées le long d'une trajectoire (Z) prédéterminée sur la pièce à traiter (100). Selon l'invention, - un intervalle d'impulsion temporel (t) entre les impulsions laser (L) individuelles générées et/ou - une énergie d'impulsion (Pi) des impulsions laser (L) et/ou - un diamètre de rayonnement (D) des impulsions laser (L) et/ou - la trajectoire (Z) prédéterminée sont spécifiquement soumis à un bruit.
Patent EP-4005057-A1 (EP)
Inventor: NOTARI NICOLA
IPC: H02J9/06
Filed: 2020-07-31
Abstract: A power supply system (10) comprises an AC input (101), an AC output (103), and a DC input (102); a DC intermediate circuit (150); a first converter (210) connected, via a first bistable switching circuit (310), between the AC input (101) and the DC intermediate circuit (150); a second converter (220) connected, via a second bistable switching circuit (320), between the DC intermediate circuit (110) and the AC output (103); a third converter (230) connected, via a third bistable switching circuit (330, 331), between the DC input (102-1, 102-2) and the DC intermediate circuit (150); a bypass circuit (250) connected, via a bypass bistable switching circuit (350), between the AC input (101) and the AC output (103) and configured to provide a bypassing path from the AC input (101) to the AC output (103); and a control unit (500) configured to control an operation mode out of a plurality of operation modes of the power supply system, wherein in each operation mode of the plurality of operation modes, at least one of the bistable switching circuits (310, 320, 330, 331 350) is in a galvanically isolated state.
Patent EP-3924027-A1 (EP)
Inventor: GUNEY MEMDUH
IPC: A61M16/06
Filed: 2020-02-11
Abstract: A patient interface comprises a plenum chamber and a seal-forming structure. The seal-forming structure comprises a support structure arranged to support a sealing portion that is adapted to sealing engage the patient's face in use. The seal-forming structure may also include a seal biasing portion configured to inflate under pressurization within the cavity in the cushion assembly in use to extend the reach of the sealing portion and decouple the sealing portion from external forces.
Patent EP-4179464-A1 (EP)
Inventor: DOERING SVEN
IPC: G06K19/07
Filed: 2020-07-07
Abstract: The present disclosure provides in various aspects for a method of forming a prelam body (100) of a smart card and a prelam body (100) of a smart card. In some illustrative embodiments, a prelam body of a smart card comprises at least one contact terminal patch (1), which comprises a patch base layer (3) and a plurality of conductive pads (5) provided on a surface of the patch base layer, wherein the plurality of conductive pads is arranged on the patch base layer in accordance with a predefined interconnection design, and a prelam sheet (20) with a plurality of openings (22), each opening accommodating a dedicated one of the conductive pads, wherein the at least one contact terminal patch is mounted to the prelam sheet.
Patent EP-3931466-A1 (EP)
Inventor: ARCE ARTURO M
IPC: B64C13/00
Filed: 2020-02-24
Abstract: A rotary actuator has a stop module configured to mechanically link two gear stages travelling at different rotational speeds when an end-of-stroke travel limit is reached, thereby causing the rotary actuator to bind because relative motion between the gear stages is impeded.
Patent EP-3933944-A1 (EP)
Inventor: ITO HIROAKI
IPC: G09F9/00
Filed: 2020-01-15
Abstract: A micro-light-emitting diode (LED) mounting board includes a substrate (1) having a mount surface (1a) receiving multiple micro-LEDs, and at least one pixel unit (15) located on the mount surface (1a) and including the multiple micro-LEDs (74R, 74G, 74B) having different emission colors to operate as a basic element of display. The multiple micro-LEDs (74R, 74G, 74B) include vertical stacks of multiple first electrodes (61R, 61G, 61B), multiple emissive layers (74RL, 74GL, 74BL), and multiple second electrodes (62R, 62G, 62B). The at least one pixel unit (15) includes a power electrode pad (60S) connected to each of the multiple second electrodes (62R, 62G, 62B). The power electrode pad (60S) is spaced from each of the multiple first electrodes (61R, 61G, 61B) by a distance (L1, L2, L3) greater than an interelectrode distance (L4, L5) between adjacent first electrodes of the multiple first electrodes (61R, 61G, 61B).
Patent EP-4021508-A1 (EP)
Inventor: SENECI ANTONIO ENRICO
IPC: A23L33/175
Filed: 2020-08-27
Abstract: The object of the present invention is the use of arginine and/or a salt thereof as a stabilizer of an acid active ingredient having a pKa of between 1 and 5 such as S-Adenosyl-L-methionine, and an edible formulation comprising an acid active ingredient, arginine and/or a pharmaceutically acceptable salt thereof, and at least one physiologically acceptable excipient.
Patent EP-4089403-A1 (EP)
Inventor: RODRIGUEZ ROSAS RAFAEL
IPC: B64D39/00
Filed: 2020-01-13
Abstract: Cameras and lights positioning system for hose inspection during air-to-air refueling, which comprises a substructure that can be attached to a container or capsule or Pod, one or two guidance-substructures (13) that enclose the hose, a toroid volume, to house the cameras (22) and lights (23) and a cameras and lights control subsystem. The system allows for the cameras (22) and lights (23) to maintain a fixed relative position with respect to the hose (1) during moments of imagery acquisition, despite the inclination and the five different movements that the hose has and makes, at the same time allowing protuberances (38) to pass through the system.
Patent EP-3935593-A1 (EP)
Inventor: SIMONS JORDAN
IPC: H04L9/32
Filed: 2020-03-06
Abstract: Systems, methods, and software are disclosed herein to generate a customized view of a blockchain transaction. A blockchain of block entries requested by a plurality of users from user devices is maintained in a distributed network of nodes. The block entries each comprise a plurality of data portions that are each associated with an access level. A request to view one or more data portions of a block entry is received which includes an access code associated with at least one access level. The access code in the request is evaluated with the blockchain of block entries to identify one or more data portions associated with the access level. A customized view of the block entry is generated which includes the one or more data portions associated with the access level. Enhanced operational efficiency and customer convenience is thereby provided in industries including parking, hotels, and autonomous vehicle fleets.