baber/WOPTO huggingface dataset:
Patent MX-2019008802-A (MX)
Title: Sound broadcasting system.
Inventor: CHRISTIAN HEIL
IPC: H04R1/32
Filed: 2018-01-10
Abstract: The invention relates to a sound broadcasting device (1) comprising a high-frequency section (2) including at least one high-frequency acoustic source (SHF), and a medium-frequency section (3, 4) including at least two medium-frequency sources (SMF), the acoustic sources (SHF, SMF) being vertically superposed, where the medium-frequency section (3, 4) comprises a lower sub-section (3), arranged below the high-frequency section (2) and comprising at least one medium-frequency acoustic source (SMF), and an upper sub-section (4), arranged above the high-frequency section (2) and comprising at least one medium-frequency acoustic source (SMF), where the vertical directivity of the high-frequency section (2) has an incline, relative to the horizontal (H), that is substantially equal to the incline (?MF) of the vertical directivity of the medium-frequency section (3, 4) relative to the horizontal (H), so that the overall vertical directivity of the device (1) has a non-zero incline (?Dir) relative to the horizontal (H).
Patent MX-2019009882-A (MX)
Title: Modular furniture system.
Inventor: Jacek STYRC
IPC: F16B12/44
Filed: 2018-02-15
Abstract: A framework for modular furniture comprises a plurality of structural members interconnected by brackets. The brackets include at least one tubular socket to receive a respective one of the structural members. The sockets have at least one planar face, and an array of holes on the planar face of the socket to permit connection of an attachment to the bracket to support ancillary components. The array of holes is arranged as two parallel rows spaced apart to define a grid.
Patent MX-2019010460-A (MX)
Title: Population-based immunogenic peptide identification platform.
Inventor: JULIANNA LISZIEWICZ
IPC: G01N33/50
Filed: 2018-03-02
Abstract: The disclosurerelates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing pharmaceutical compositions comprising such polypeptide fragments, pharmaceutical compositions comprising such polypeptide fragments, and methods of treatment using such compositions. The methods comprise identifying a fragment of the polypeptide that binds to multiple HLA of individual subjects.
Patent MX-2019011910-A (MX)
Title: Bispecific antibodies specifically binding to pd1 and lag3.
Inventor: STEFAN SEEBER
IPC: C07K16/28
Filed: 2018-04-03
Abstract: The invention relates to bispecific antibodies comprising a first antigen binding domain that specifically binds to PD1 and a second antigen binding domain that specifically binds to LAG3. The invention further relates to methods of producing these molecules and to methods of using the same.
Patent MX-2019012007-A (MX)
Title: Processes of making and crystalline forms of a mdm2 inhibitor.
Inventor: LAWRENCE R MCGEE
IPC: A61K31/451
Filed: 2015-12-08
Abstract: The present invention provides processes for making 2-((3R,5R,6S)-5-(3- chlorophenyl)-6-(4-chlorophenyl)-l-((S)-l-(isopropylsulfonyl)-3 -methylbutan-2-yl)-3- methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.
Patent MX-2019013118-A (MX)
Title: Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins.
Inventor: TAKASHI KEI KISHIMOTO
IPC: A61K9/51
Filed: 2013-10-28
Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
Patent MX-2020002867-A (MX)
Title: Glucosylceramide synthase inhibitors.
Inventor: BOURQUE ELYSE
IPC: A61K31/439
Filed: 2013-09-10
Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
Patent MX-2020003171-A (MX)
Title: Load control device having a wide output range.
Inventor: KOBER STEVEN J
IPC: H05B44/00
Filed: 2018-02-23
Abstract: A load control device (e.g., an LED driver) for controlling the intensity of a lighting load (e.g., an LED light source) may provide a wide output range and flicker-free adjustment of the intensity of the lighting load. The load control device may comprise a load regulation circuit, a control circuit, and a filter circuit (e.g., a boxcar filter circuit) that operates in a different manner in dependence upon a target current. When the intensity of the lighting load is near a low-end intensity, the control circuit may adjust an operating frequency of the load regulation circuit in response to the target current, and may control the filter circuit to filter a current feedback signal during a filter window that repeats on periodic basis. When the intensity of the lighting load is near a high-end intensity, the control circuit may control the filter circuit to constantly filter the current feedback signal.
Patent MX-2020007259-A (MX)
Title: Bisulfite-free, base-resolution identification of cytosine modifications.
Inventor: SONG CHUNXIAO
IPC: C12P17/16
Filed: 2019-01-08
Abstract: This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methylcytosine, 5- hydroxymethylcytosine, 5-carboxylcytosine and 5- formylcytosine.
Patent MX-2020008750-A (MX)
Title: Materials and methods for attracting and controlling plant-pathogenic nematodes.
Inventor: FARMER SEAN
IPC: A01N63/00
Filed: 2019-02-20
Abstract: The invention provides materials and method for attracting and controlling plant-pathogenic nematodes. In specific embodiments, compositions are provided comprising Valerian root, which draws the nematodes away from plants, and/or a microbe-based composition comprising nematicidal microorganisms and/or their growth by-products, which control the nematodes upon contact. The compositions can be applied to a plant's environment, including soil, to attract and control nematodes, and to reduce and/or prevent plant damage caused by nematodes.
Patent MX-2020008856-A (MX)
Title: Method for the catalytic conversion of glycerol to propanol.
Inventor: SCHÖFFL PAUL
IPC: B01J23/652
Filed: 2019-02-28
Abstract: The invention relates to a method, device, catalyst and to a method for producing a catalyst for the catalytic conversion of a substance mixture containing glycerol to propanol in a fixed-bed reactor (2), wherein substrates of the catalyst have inorganic materials and/or metal oxides, characterized in that the substrates have a pore diameter at the surface of between 10 and 25 angstroms, preferably between 12 and 20 angstroms, particularly preferably 15 angstroms.
Patent MX-2021000771-A (MX)
Title: Aerosolisable formulation.
Inventor: MATHIE KLAUS
IPC: A24B15/00
Filed: 2019-07-18
Abstract: An aerosolisable formulation is disclosed which comprises (i) one or more aerosol-forming agents; and (ii) a flavouring agent, wherein the flavouring agent is an extract obtained from an alcoholic beverage, and wherein the extract contains less than about 5% v/v ethanol. Also disclosed is a process for forming an aerosol, a contained aerosolisable formulation, an electronic aerosol provision system and the use of an extract obtained from an alcoholic beverage as a flavouring agent in an electronic aerosol provision system, wherein the extract contains less than about 5% v/v ethanol.
Patent MX-2021002027-A (MX)
Title: Pharmaceutical composition for treating cancer comprising metal ion-bound ionic compound.
Inventor: PAI CHUAL MIN
IPC: A61K47/52
Filed: 2019-08-19
Abstract: The present invention relates to a pharmaceutical composition for cancer treatment. More specifically, the pharmaceutical composition for cancer treatment comprises an ionic compound in which two different compounds selected from among ascorbic acid, dichloroacetic acid, and lactate, are bound to calcium ions, wherein as the compounds different from each other are simultaneously taken up by cancer cells, said compounds act on main metabolizing enzymes having different mechanisms from each other, thereby interfering with cancer cell metabolism in a multiplicative and complex manner. Thus, the pharmaceutical composition for cancer treatment exhibits a superior therapeutic effect than that of an anticancer drug focused on a single mutation or on a cancer cell growth signal; and is less vulnerable to the emergence of drug resistance, and thus, can more effectively suppress activities of cancer cells, such as proliferation, invasion, and migration.
Patent MX-2021003566-A (MX)
Title: Therapeutic uses of atomic quantum clusters.
Inventor: BUCETA FERNÁNDEZ DAVID
IPC: A61K33/38
Filed: 2019-09-25
Abstract: There is provided an invention relating to compositions and therapeutic uses of atomic quantum clusters (AQCs), in particular compositions consisting essentially of AQCs comprising 5 zero-valent transition metal atoms for use in the treatment of a cell proliferative disorder.
Patent MX-2021006380-A (MX)
Title: A method of preparing a gelling agent, the gelling agent obtained thereby, and the use of said gelling agent.
Inventor: LARSEN FINN
IPC: A61K47/32
Filed: 2019-11-28
Abstract: A method of preparing a gelling agent, the gelling agent obtained thereby, and the use of said gelling agent. The present invention relates to a method of obtaining a novel gelling agent. Said method comprises adding ethylcellulose, to a mixture of propyleneglycol laurate and propyleneglycol isostearate at a temperature of between 90Â°C and 110Â°C. The method according to the invention provides a simpler, less energy consuming, cheaper and easier way of obtaining a substantially gelling agent which can be used for manufacturing an oleogel and/or a bigel, for cosmetic and/or pharmaceutical use.
Patent MX-2021007215-A (MX)
Title: Cold rolled and heat-treated steel sheet and method of manufacturing the same.
Inventor: ALEXANDRE PATRICE
IPC: C22C38/38
Filed: 2019-12-17
Abstract: The invention deals with a cold rolled and heat-treated steel sheet having a composition comprising, by weight percent: C 0.3 - 0.4 %, Mn 2.0 - 2.6 %, Si: 0.8 - 1.6 %, Al 0.01 - 0.6 %, Mo 0.15 - 0.5 %, Cr 0.3 - 1.0 %, Nb â¤ 0.06 %, Ti â¤ 0.06 %, Ni â¤ 0.8 %, S â¤ 0.010 %, P â¤ 0.020 % and N â¤ 0.008 %, the remainder of the composition being iron and unavoidable impurities resulting from the smelting, and having a microstructure consisting of, in surface fraction: between 15% and 30% of retained austenite, said retained austenite having a carbon content of at least 0.7%, between 70% and 85% of tempered martensite, at most 5% of fresh martensite and at most 5% of bainite. It also deals with a manufacturing method thereof.
Patent MX-2021008012-A (MX)
Title: Flexible schema for language model customization.
Inventor: DUMOULIN BENOIT
IPC: G10L15/30
Filed: 2016-09-20
Abstract: The customization of language modeling components for speech recognition is provided. A list of language modeling components may be made available by a computing device. A hint may then be sent to a recognition service provider for combining the multiple language modeling components from the list. The hint may be based on a number of different domains. A customized combination of the language modeling components based on the hint may then be received from the recognition service provider.
Patent MX-2021010342-A (MX)
Title: Adapter for canister filling system and method for filling a gas canister.
Inventor: SHMUELI EYAL
IPC: F17C13/06
Filed: 2020-11-16
Abstract: An adapter for a canister filling system includes a body having an opening that is shaped to enable insertion of a valve of a gas canister for holding a pressurized or liquefied gas, into an interior space of the body, leaving a sealed gap between at least a portion of a lateral aspect of the valve and an internal surface of the body facing the interior space; and at least one channel that is configured to conduct pressurized or liquified gas from a canister filling system into the sealed gap in the interior space, so as to reach one or more lateral exterior ports of the valve of the gas canister that open laterally to a longitudinal axis of a body of the gas canister, when the valve is inserted in the interior space, to facilitate filling of the gas canister with the pressurized or liquified gas through said one or more lateral exterior ports of the gas canister.
Patent MX-2021010344-A (MX)
Title: Method for selecting subject likely benefiting from pharmaceutical composition for treating or preventing cancer.
Inventor: GOTO MASASHI
IPC: C12Q1/6851
Filed: 2020-02-27
Abstract: Disclosed is a method for selecting a subject likely benefiting from a pharmaceutical composition for treating or preventing cancer, said method comprising: a step for identifying the presence or absence of a mutation in Tumor Protein p53 (TP53) gene and/or BCL6 co-repressor (BCOR) gene with the use of a sample collected from the subject; and a step for, when TP53 wild type and/or BCOR wild type are identified, then providing an indication that this subject likely benefits from the pharmaceutical composition.
Patent MX-2021010648-A (MX)
Title: System and method for a parking system.
Inventor: LA TONY
IPC: G06Q20/32
Filed: 2020-03-05
Abstract: Systems and methods for facilitating parking sessions are provided. The system including at least one server that is configured to: receive through a communication network, from a first remote user equipment (UE) device, information associating a unique identification (UID) encoded on an passive NFC tag with a parking zone identification (ID) that identifies a physical parking zone; update a database to associate the UID with the parking zone ID and parking rate data for the physical parking zone; host or receive a URL that includes the UID; receive, through the communication network, a message including: a license plate number from a second remote user equipment (UE) device that has read the URL from the NFC tag; and record a parking session for the license plate number for the parking zone based on the message from the second remote UE.
Patent MX-2021011237-A (MX)
Title: Composite microcapsules.
Inventor: DARDELLE GREGORY
IPC: B01J13/14
Filed: 2020-07-29
Abstract: The present invention relates to a composite microcapsule slurry comprising at least one microcapsule having: - an oil-based core comprising an hydrophobic material, preferably a perfume, - a composite shell comprising a first material and a second material, wherein: â¢ the first material and the second material are different, â¢ the first material is a coacervate, â¢ the second material is a polymeric material, and â¢ the weight ratio in the slurry between the first material and the second material is comprised between 50:50 and 99.9:0.1.
Patent MX-2021012639-A (MX)
Title: Pyrrolopyrimidines as cftr potentiators.
Inventor: ZAPF CHRISTOPH WOLFGANG
IPC: A61K31/519
Filed: 2017-11-17
Abstract: The present invention relates to compounds of Formula (I), wherein R<sup>1</sup> a, R<sup>1</sup> b, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, W, Y, and Z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiators of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). The invention also discloses pharmaceutical compositions comprising the compound, optionally in combination with additional therapeutic agents, and methods of potentiating, in mammals, including humans, CFTR by administration of the compounds. These compounds are useful for the treatment of cystic fibrosis (CF), asthma, bronchiectasis, chronic obstructive pulmonary disease (COPD), constipation, Diabetes mellitus, dry eye disease, pancreatitis, rhinosinusitis, Sjogren's Syndrome, and other CFTR associated disorders.
Patent MX-2021012640-A (MX)
Title: Method for the diagnosis or prognosis of colorectal cancer or a pre-cancerous stage thereof.
Inventor: DÍAZ LAGARES ÁNGEL
IPC: C12Q1/68
Filed: 2020-04-15
Abstract: The method of the invention implies the determination of the methylation status of the gene <i>LINC00473</i> promoter in a liquid biopsy obtained from the patient.
Patent MX-2022001803-A (MX)
Title: [1,2,4]triazolo[1,5-c]quinazolin-5-amines.
Inventor: SCHMEES NORBERT
IPC: A61P35/00
Filed: 2020-08-10
Abstract: The present invention covers [1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds of general formula (I) in which R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients.
Patent MX-2022001834-A (MX)
Title: Combination therapies of hdac inhibitors pd-1 inhibitors.
Inventor: BISSONNETTE REID P
IPC: A61K31/13
Filed: 2018-11-07
Abstract: Provided herein are combinations that include an HDACi and a PD-1 inhibitor that are useful for treating cancer, including reducing and/or preventing cancer metastasis. The combination is also useful for treating cancer that has been previously treated with a PD-L1 inhibitor.
Patent MX-2022004637-A (MX)
Title: Chagas disease vaccine antigens with improved stability and decreased aggregation.
Inventor: ZHAN BIN
IPC: C07K14/44
Filed: 2020-10-14
Abstract: Provided herein are compositions and methods for the prevention and treatment of Chagas disease and acute and chronic symptoms thereof. The compositions comprise recombinant proteins based on an amino terminal fragment of the TSA-1 protein from <i>Trypanosoma cruzi</i>. In the fragment, one or more Cys residues is mutated to prevent the formation of disulfide bonds and to enhance solubility. The recombinant proteins also include a carboxyl terminal fragment of the TSA-1 protein from <i>Trypanosoma cruzi</i> to provide additional stability and solubility. The resulting recombinant protein remains soluble upon prolonged storage at low temperatures and elicits a robust immune response upon administration, including decreasing the number of inflammatory cells in heart tissue of subjects.
Patent MX-2022005537-A (MX)
Title: Catalysts for pet methanolysis.
Inventor: SHARPE ROBERT JACKS
IPC: C07C67/03
Filed: 2020-12-10
Abstract: Provided is a process for depolymerization of a poly(C2-C4 alkylene terephthalate), which comprises contacting a poly(C2-C4 alkylene terephthalate) with methanol and a catalyst chosen from potassium carbonate, sodium carbonate, magnesium methoxide, 1,8-diazabicyclo[5.4.0]undec-7-ene, and triazabicyclodecene, at a temperature sufficient to effect said depolymerization. The process of the invention can be carried out a substantially lower temperature and requires less methanol than necessary for zinc acetate-catalyzed reactions, and is sufficiently robust to tolerate lower-quality poly(C2-C4 alkylene terephthalate) scrap feeds.
Patent MX-2022009560-A (MX)
Title: Process for making adenoassociated viral vectors.
Inventor: CAWOOD RYAN
IPC: C12N15/86
Filed: 2021-02-03
Abstract: The invention relates to a nucleic acid molecule encoding at least one AAV Rep polypeptide, wherein one or more of the AAV (p5), (p19) and (p40) promoters have been modified to reduce or eliminate expression of one or more of the Rep polypeptides, or the nucleic acid molecule does not encode functional (Rep52) or (Rep40) polypeptides, or the nucleic acid molecule does not encode a functional adenovirus inhibitor sequence. The invention also relates to a process for producing recombinant AAV vectors through the use of a 2-adenovirus system, wherein all of the genes required for AAV replication and packaging (i.e. an AAV rep sequence of the invention, AAV cap and the AAV transfer vector comprising a transgene) may be encoded within two adenoviruses.
Patent MX-2022009783-A (MX)
Title: Proximity assay.
Inventor: LIU JIA
IPC: C12Q1/682
Filed: 2021-02-11
Abstract: The present disclosure provides assay methods for the detection and/or quantification of an analyte in a sample. In some examples, the methods detect and/or quantify an active analyte in a sample.
Patent MX-2022012229-A (MX)
Title: Anti-cd6 antibody compositions and methods for treating and reducing negative effects of a coronavirus including covid-19.
Inventor: NAIR PRADIP
IPC: C07K16/28
Filed: 2021-04-03
Abstract: The present invention provides the use of anti-CD6 antibodies that specifically bind to domain 1 of CD6 for treating effects of a coronavirus or bacterial agent and particularly COVID-19 and variants thereof. The anti-CD6 antibodies of the present invention exhibit therapeutic activity by reducing the overactive immune response, such as the high expression levels of cytokines.
Patent MX-2022015079-A (MX)
Title: Hsd17b13 variants and uses thereof.
Inventor: ABUL-HUSN NOURA S
IPC: A61K31/713
Filed: 2019-07-23
Abstract: Provided are compositions related to <i>HSD17B13 </i>variants, including isolated nucleic acids and proteins related to variants of <i>HSD17B13</i>, and cells comprising those nucleic acids and proteins. Also provided are methods related to <i>HSD17B13 </i>variants. Such methods include methods for modifying a cell through use of any combination of nuclease agents, exogenous donor sequences, transcriptional activators, transcriptional repressors, and expression vectors for expressing a recombinant <i>HSD17B13 </i>gene or a nucleic acid encoding an HSD17B13 protein. Also provided are therapeutic and prophylactic methods for treating a subject having or at risk of developing chronic liver disease.
Patent MX-2023000118-A (MX)
Title: Nozzle and Beverage Preparation Machine.
Inventor: DEES HENDRIK JOHAN
IPC: A47J31/44
Filed: 2021-06-23
Abstract: 16 ABSTRACT Nozzle and Beverage Preparation Machine FIG 2. A nozzle 20 has a fluid flow passage 26 which defines a fluid flow path from an inlet 5 end of said passage towards an outlet end of said passage. A restrictor 29a is movable under the control of an actuation system 27 relative to the passage to vary the minimum cross-sectional area of the fluid flow path through the passage. The restrictor 29 is moved to project into the passage to provide a restricted opening in the passage or removed from the passage to allow an unrestricted flow through the 10 passage. The nozzle 20 is particularly suitable for use in a beverage preparation machine to generate microfoam in a beverage. When the restrictor 29 is retracted from the passage 29, the passage and the restrictor can be cleaned by flushing the nozzle. The restrictor 29 may be a pin-like member aligned with the passage and moveable parallel to the axis of the passage.15.
Patent MX-PA00007535-A (MX)
Inventor: FARINATO RAYMOND SALVATORE
IPC: C08L101/14
Filed: 2000-08-01
Abstract: The invention provides mixtures of high molecular weight, water soluble, cationic, structured polymers, with high molecular weight, water soluble, cationic polymers that are linear or have a lower degree of structure. The mixtures are useful to dehydrate dispersions of suspended solids, reaching good rates of dehydration at relatively low dosage levels.
Patent MX-PA00009255-A (MX)
Title: Coating epdm rubber membranes.
Inventor: THOMAS JAMES ENNIS
IPC: C08J7/043
Filed: 2000-09-21
Abstract: Adhesion between a coating and an EPDM rubber membrane may be improved by pre-treating the surface of the EPDM rubber membrane with an aqueous detergent composition having a pH above 8 and comprising from 1 to 10 % by weight phosphate and from 1 to 10 % by weight silicate, before application of the mastic.