baber/WOPTO huggingface dataset:
Patent CA-3158112-A1 (CA)
Inventor: GREENSTEIN ANDREW
IPC: C07D471/04
Filed: 2020-10-14
Abstract: Methods for treating a cancer patient with a neutrophil-to-lymphocyte ratio (NLR) greater than 3 are disclosed, comprising administering a nonsteroidal glucocorticoid receptor antagonist (GRA) to such a cancer patient, effective to reduce the patient's NLR. The methods include administering a nonsteroidal GRA and a cancer treatment to such a cancer patient, effective to reduce the patient's NLR and enhance the treatment of the cancer patient. The GRA may be orally administered. The nonsteroidal GRA may be a nonsteroidal compound comprising a heteroaryl ketone fused azadecalin structure (e.g., relacorilant) or an octahydro fused azadecalin structure (e.g., exicorilant). The cancer treatment may include chemotherapy, immunotherapy, radiation therapy, administration of an anti-angiogenic agent, administration of a growth factor inhibitor, and surgery. The methods may enhance the cancer treatment, improve the prognosis of the cancer patient, improve the survival of the cancer patient, and provide beneficial clinical effects and advantages to the patient.
Patent CA-3160034-A1 (CA)
Inventor: BIGI MANUELE
IPC: F04D25/06
Filed: 2020-12-10
Abstract: The centrifugal compressor comprises a casing and a rotor arranged in the casing and configured to rotate around a vertical rotation axis. The rotor comprises at least one impeller having an impeller suction side and an impeller delivery side. The compressor includes a gas inlet and a gas outlet, as well as a gas flow path extending from the gas inlet to the gas outlet. An inlet plenum extends from the gas inlet towards the impeller suction side. At least one suction tube having a lower suction end and an upper discharge end is arranged such that the lower suction end thereof is arranged at a bottom of the inlet plenum. The suction tube extends upwardly towards the impeller suction side.
Patent CA-3162041-A1 (CA)
Inventor: OEHRING JARED
IPC: E21B43/26
Filed: 2020-12-30
Abstract: A pump control system includes an additive pump (204), the additive pump (204) being fluidly coupled to a component (202) of a hydraulic fracturing system. The system also includes an additive container (206), the additive container (206) configured to provide an additive to the additive pump (204) via a flow path. The system further includes a diversion system (208), arranged within the flow path between the additive pump (204) and the component (202) of the hydraulic fracturing system, the diversion system (208) configured to redirected at least a portion of additive directed toward the component (202) of the hydraulic fracturing system. The system includes a calibration system configured to receive the redirected portion of the additive, the calibration system adapted to adjust one or more operational parameters of the additive pump (204) responsive to an evaluation of a flow parameter of the redirected portion of the additive.
Patent CA-3162116-A1 (CA)
Inventor: WALDNER PAUL
IPC: E04B1/35
Filed: 2022-06-09
Abstract: A concrete and steel insulated building is constructed by forming excavated holes and inserting into each hole a 3-dimensional reinforcing bar cage having a length so as to define reinforcement for a pile and to stand upwardly of the hole to a height above the hole to provide reinforcement for a column having a height of the building wall. The pile is formed by casting concrete into each hole around the cage and setting the material so as to define an upper surface of the pile at or above the ground. With the pile set, a formwork is defined by a series of stacked openable form components standing upwardly and a further body of concrete is cast into the formwork to form the column which is integrated with the pile by the cage. A roof and insulated walls are applied on the building supported by the columns.
Patent CA-3162425-A1 (CA)
Title: Device abstraction proxy
Inventor: GOLDBURG MARC
IPC: H04L41/044
Filed: 2010-11-02
Abstract: Described are systems and methods for implementing and operating a Device Abstraction Proxy (DAP). In one embodiment, the DAP includes a communications interface to connect the DAP to one or rnore access aggregation devices, each having a plurality of physical ports to provide Digital Subscriber Line (DSL) communication services to a plurality of rernote DSL  terminals via the plurality of physical ports. The DAP may further include a mernory and processor to execute or instantiate a virtual access aggregation device, in which a subset of the plurality of physical ports are allocated and linked to corresponding logical ports. The DA.P may further include a global rule -set module to define operational constraints for the DSL communication services, and a management interface to allow at least one broadband access management system to rnanage the subset of physical ports allocated to the virtual access aggregation device subject to the operational constraints. The DAP may further include a Dynamic Spectrum Management (DSM) module to apply optimization techniques for reducing cross -talk among lines traversing a common binder by reducing transmit power or assigning communication spectrums to lines that are less likely to create interference noise.
Patent CA-3162877-A1 (CA)
Inventor: WANG FUCHANG
IPC: A47C7/62
Filed: 2021-07-07
Abstract: The present disclosure discloses a vibration motor, and a rhythm device, a rhythm mattress, a rhythm sofa and a rhythm deck chair comprising the vibration motor, comprising a housing, a motor provided in the housing, a coupler and a vibration assembly, wherein the vibration assembly comprises a rotating shaft and an eccentric block connected with the rotating shaft and eccentrically provided, the rotating shaft and the power output shaft of the motor are coaxially provided and are in transmission connection through a coupler; a bearing is fixed on the inner wall of the housing, the rotating shaft penetrates into the bearing and is rotatably connected with the bearing, and the motor is fixedly provided with the inner wall of the housing. The present disclosure is simple in structure, stable and efficient in transmission, the rotating shaft and the motor are coaxially provided and can stably transmit vibration, and the whole vibration of the vibration motor is regular and stable. Compared with the prior art, the vibration stability is improved to a certain extent, and the vibration intensity is guaranteed so as to provide effective massage, relieve human fatigue and effectively promote people to quickly enter deep sleep.
Patent CA-3164691-A1 (CA)
Inventor: WALL JONATHAN S
IPC: A61K39/395
Filed: 2021-01-15
Abstract: L'invention concerne des récepteurs chimériques comprenant des régions de liaison aux amyloïdes, ainsi que des cellules comprenant lesdits récepteurs chimériques. L'invention concerne en outre des méthodes de traitement de maladies liées aux amyloïdes par administration d'une cellule comprenant un récepteur chimérique.
Patent CA-3172142-A1 (CA)
Title: Biomass direct reduced iron
Inventor: DRY RODNEY JAMES
IPC: C21B13/00
Filed: 2021-03-19
Abstract: A process and an apparatus for producing direct reduced iron ("DRI") from iron ore and biomass are disclosed. The process includes heating a batch of iron ore and biomass in a batch oven (3) and reducing iron ore and forming a solid DRI product having a metallisation of 80-99% and generating an offgas. The process includes discharging the solid product at the end of the batch cycle and discharging offgas during the course of the batch cycle. The process operates the batch oven in a temperature range of 700-1100?C in a batch cycle time of 10-100 hours.
Patent CA-3172902-A1 (CA)
Title: Methods for ex vivo enrichment and expansion of tumor reactive t cells and related compositions thereof
Inventor: LANGER TIMOTHY J
IPC: A61K35/17
Filed: 2021-03-01
Abstract: Provided herein are methods for manufacturing of tumor reactive T cells that includes ex vivo enrichment of, and expansion of, cells secreting chemokine (C-X-C motif) ligand 13 (CXCL13); cells surface positive for C-X-C chemokine receptor type 5 (CXCR5); and/or one or more of CD39, PD-1 and TIGIT. Also provided are populations of T cells produced by methods described herein and pharmaceutical compositions thereof.
Patent CA-3173650-A1 (CA)
Inventor: PARTSCH GEORGE J
IPC: B65D41/04
Filed: 2021-03-31
Abstract: L'invention concerne un système de capsulage universel destiné à être mis en ?uvre dans n'importe quelle partie de couplage de bouteille pour capsuler de manière étanche des ouvertures de bouteille de diverses tailles. Une telle partie de couplage de bouteille peut être une buse à douche, un bec verseur de liqueur, un bec verseur d'huile d'olive, et simplement une capsule de fermeture de bouteille. Ce système de capsulage universel comporte un sommet de capsule et un joint circulaire élastique qui s'étend vers le bas.
Patent CA-3173737-A1 (CA)
Title: Methods of making chimeric antigen receptor-expressing cells
Inventor: BROGDON JENNIFER
IPC: A61P35/00
Filed: 2021-02-26
Abstract: This disclosure provides methods of making immune effector cells (for example, T cells, NK cells) that comprise (i) a nucleic acid molecule that encodes a controllable chimeric antigen receptor (CCAR) or (ii) a nucleic acid molecule that encodes a CAR and a regulatory molecule, and compositions generated by such methods.
Patent CA-3175617-A1 (CA)
Inventor: PINEL FLORIAN
IPC: G06F30/20
Filed: 2021-04-28
Abstract: Provided are techniques for optimized deployment of analytic models in an edge topology. A description of a multi-tiered edge topology with a plurality of nodes, a multimedia stream analytics composition, and performance objectives are received, where the multimedia stream analytics composition includes tasks that use analytic models. The analytic models are optimized and clustered to form clusters of optimized analytic models. A representative optimized analytic model is selected from each of the clusters. A configuration recommendation is determined that indicates deployment of the tasks and of each selected representative optimized analytic model on the plurality of nodes to meet the performance objectives. One or more workflows are generated from the configuration recommendation and executed on the plurality of nodes to generate output for the multimedia stream analytics composition.
Patent CA-3176168-A1 (CA)
Title: Application of compounds in controlling or killing mites
Inventor: ZHANG YAN
IPC: A61P33/14
Filed: 2021-04-23
Abstract: An application of a series of compounds in controlling or killing mites. It has been found by comparison that the compounds, when compared with a control group, can reduce the survival time of mites; in particular, taraxerol, diosmetin, and taraxasteryl acetate can significantly shorten the survival time of mites, and can be used for miticide and mite control products (such as drugs, cosmetic products, daily products and so on).
Patent CA-3177196-A1 (CA)
Title: Rupture disc assembly
Inventor: GILLIS BROCK
IPC: E21B34/06
Filed: 2021-03-29
Abstract: Disclosed is a rupture disc assembly for use in making a temporary seal in a vessel such as a casing string. The rupture disc assembly may generally include (A) a rupture disc having a side surface having a shallow taper inward towards a bottom surface of the rupture disc (B) an actuating mechanism including (i) an outer sled having an inner supporting surface forming a taper complimentary to the shallow taper of the side surface, (ii) an inner sled disposed within the outer sled and having a support shoulder to support the bottom surface of the rupture disc and (iii) a securing mechanism and (C) a housing to house the rupture disc and actuating mechanism.
Patent CA-3177338-A1 (CA)
Inventor: CHACON MARCO A
IPC: A61K31/202
Filed: 2021-04-29
Abstract: Methods and compositions comprising free fatty acids for the treatment, including prevention, of viral infections, including the treatment of Acute Respiratory Distress Syndrome (ARDS). The compositions comprising free fatty acids, optionally linolenic acid, linolenic acid, and/or palmitic acid, may be used in methods for treating viral infections, optionally, coronavirus infections, for example, SARS-CoV, MERS-CoV, and/or SARS-CoV-2/COVID-19, and influenza virus infections, optionally, H1N1 and/or H5N1.
Patent CA-3177521-A1 (CA)
Inventor: O'SHEA CONOR
IPC: A61B17/00
Filed: 2021-05-06
Abstract: A cutting assembly for a surgical instrument including an outer hub, an outer tube, a cutting implement, and a drive hub. A retention flange of the drive hub is arranged to retain the cutting shaft within the outer tube. The cutting assembly may include a seal, and the retention flange may contact the seal. An irrigation spacer may provide a stop of distal axial movement of the drive hub for permitting fluid to flow through irrigation passageways. The drive assembly may include an irrigation port and a suction port with a proximal end of the irrigation port may positioned axially distal to a proximal portion of the suction port. The irrigation port may be coupled to a handpiece, and the suction port may be coupled to a back cap. A handpiece may include a saddle region, recesses, and/or an apex region to facilitate ergonomic handling of the surgical instrument.
Patent CA-3177601-A1 (CA)
Inventor: PORCO CARLO
IPC: F01D25/28
Filed: 2022-09-28
Abstract: Commissioner of Patents A NORTON ROSE FULBRIGHT Respectfully, NORTON ROSE FULBRIGHT CANADA LLP/S.E.N.C.R.L., s.r.l. tAkfluukµ4 fulkji t Caora4 geS.1-$11.0e,C.,i; t Agents for the Applicant AT/rl 2 Date Regue/Date Received 2022-09-28
Patent CA-3179378-A1 (CA)
Title: Substituted thiazolopyridines, salts thereof and their use as herbicidally active substances
Inventor: BARBER DAVID MICHAEL
IPC: C07D513/04
Filed: 2021-03-30
Abstract: The present invention relates to substituted thiazolopyridines of the general formula (I) or salts thereof, where the radicals in the general formula (I) correspond to the definitions given in the description, and to their use as herbicides, in particular for controlling weed grasses and/or broad-leaved weeds in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants.
Patent CA-3179777-A1 (CA)
Title: Method and device for recovering metal
Inventor: RINNE TERO
IPC: C25B11/043
Filed: 2021-04-27
Abstract: The present application provides a method for recovering metal from metal- containing material by leaching, the method comprising providing aqueous solution containing leaching agent precursor, providing one or more source(s) of external energy comprising a source of electric current connected to one or more non- metallic electrode(s) comprising carbon material(s) selected from graphite, graphene and derivatives thereof, and carbon nanomaterial(s) selected from carbon nanofibers, carbon nanotubes and carbon nanobuds, treating the aqueous solution with the external energy, which is electric current providing electrochemical reactions, to form hydrogen peroxide from oxygen in the aqueous solution, reacting the leaching agent precursor with the formed hydrogen peroxide to form a leaching agent and to obtain a leaching solution, providing metal- containing material, reacting the metal-containing material with the leaching solution to obtain soluble metal complexes, and recovering the soluble metal complexes. The present application also discloses a device for recovering metal from metal-containing material by leaching.
Patent CA-3180837-A1 (CA)
Inventor: BRUNING ELIZABETH
IPC: A61P31/16
Filed: 2021-04-19
Abstract: La présente invention concerne des méthodes et des compositions pour l'inhibition de la transmission de virus de la grippe, qui consiste à appliquer une composition contenant un composé de polyalkylène glycol sur une surface pouvant être infectée ou ingérée qui peut contenir des virus. L'invention concerne en outre des méthodes et des compositions pour l'inhibition de la transmission de la grippe et d'autres virus enveloppés, qui consiste à appliquer une composition contenant un composé de polyalkylène glycol et un polymère modifié hydrophobiquement (HMP) de faible masse moléculaire sur une surface pouvant être infectée ou ingérée qui peut contenir des virus.
Patent CA-3184942-A1 (CA)
Title: Stretched foamless multi-layer substrate polarizer and methods for fabricating same
Inventor: WOOLMAN JASON
Filed: 2022-12-05
Abstract: A radio frequency (RF) polarizer includes a frame having a first side and a second side spaced apart from and opposite the first side, a first polarizer substrate attached to the first side and including a plurality of conductor patterns formed on a surface of the first polarizer substrate, and a second polarizer substrate attached to the second side. The first polarizer substrate and the second polarizer substrate are attached to the first side and the second side, respectively, under tension.
Patent CA-3185235-A1 (CA)
Title: Systeme de perfusion a pression alternative pour perfuser des tissus a l'exterieur du corps
Inventor: JESSOP ISRAEL
IPC: A01N1/02
Filed: 2021-07-08
Abstract: La présente invention comprend un système de perfusion (300) pour la conservation d'un organe ou d'un tissu vasculaire à l'extérieur du corps, et des procédés associés. Le système peut comprendre un premier réservoir de fluide (308), un second réservoir de fluide (307) et un circuit de perfusion. Le circuit de perfusion peut comprendre une première voie de perfusion pour relier le premier réservoir de fluide au tissu (314), et une seconde voie de perfusion pour relier le second réservoir de fluide au tissu. Un premier ensemble de conditions peut amener le fluide contenu dans le premier réservoir de fluide à s'écouler dans une première direction antérograde depuis le premier réservoir de fluide, dans le tissu, jusqu'au second réservoir de fluide. Un second ensemble de conditions peut amener le fluide de perfusion contenu dans le second réservoir de fluide à s'écouler dans une seconde direction antérograde depuis le second réservoir de fluide, dans le tissu, jusqu'au premier réservoir de fluide.
Patent CA-3185495-A1 (CA)
Title: Catheters a entonnoir recuperable, et systemes et methodes associes
Inventor: THRESS JOHN COLEMAN
IPC: A61M1/00
Filed: 2021-06-04
Abstract: L'invention concerne des systèmes et des méthodes pour le traitement intravasculaire d'un caillot dans un vaisseau sanguin d'un patient humain. Dans un mode de réalisation, un ensemble cathéter en entonnoir comprend un corps de cathéter externe et un corps de cathéter interne s'étendant à travers le corps de cathéter externe et de façon coaxiale à celui-ci. Un entonnoir extensible peut être accouplé à une partie distale du corps de cathéter interne. L'ensemble cathéter à entonnoir comprend en outre un ensemble de commande accouplé de manière opérationnelle à la partie proximale du corps de cathéter externe et configuré pour déplacer le corps de cathéter externe entre une première position et une seconde position. Dans la première position, le corps de cathéter externe est positionné au moins partiellement sur l'entonnoir pour contraindre l'entonnoir dans un état comprimé. Dans la deuxième position, le corps de cathéter externe est rétracté de manière proximale par rapport à l'entonnoir de telle sorte que l'entonnoir peut se dilater jusqu'à un état déployé.
Patent CA-3187477-A1 (CA)
Title: Methods for managing pump-lifted wells in hydrocarbon fields
Inventor: AHN CHONG HYUN
IPC: E21B47/009
Filed: 2023-01-23
Abstract: A methodology for integrated pump and well data for managing pump-lifted wells in hydrocarbon fields is provided. Rod pumps are widely applied to various types of wells to provide uplift and may play a dominant role in the flow of hydrocarbon from reservoir to surface. Assess the state of each well and its components (including the associated rod pump) is important for optimal well and reservoir management for fields with artificially lifted wells. As such, a methodology is disclosed that performs machine learning in order to generate a machine-learned model using pump card data and at least one of well data, reservoir data, flowline data, user input data, or data generated from analysis of one or more of the well data, the reservoir data, the flowline data, or the user input data.
Patent CA-3187578-A1 (CA)
Title: Methode de traitement de sous-types de lma a l'aide d'agents de depletion de l'arginine
Inventor: KWOK SUI YI
IPC: C07K14/00
Filed: 2020-06-29
Abstract: Selon l'invention, une méthode de traitement de la leucémie myéloïde aiguë (LMA) chez un sujet qui en a besoin comprend l'administration d'une quantité thérapeutiquement efficace d'un agent de déplétion de l'arginine au sujet, la LMA étant du sous-type M0 (leucémie myéloblastique aigüe sans différenciation), M2 (leucémie myéloblastique aigüe avec maturation), M4 (leucémie myéloblastique aigüe avec maturation), M4 eos (leucémie myélomonocytique aigüe avec éosinophilie), M5 (leucémie monocytique aigüe), M6 (leucémie érythroïde aigüe) ou M7 (leucémie mégakaryoblastique aigüe) du système franco-américano-britannique (FAB). L'invention concerne également un médicament comportant un agent de déplétion de l'arginine pour traiter la LMA chez un sujet qui en a besoin, la LMA étant du sous-type M0 (leucémie myéloblastique aigüe sans différenciation), M2 (leucémie myéloblastique aigüe avec maturation), M4 (leucémie myéloblastique aigüe avec maturation), M4 eos (leucémie myélomonocytique aigüe avec éosinophilie), M5 (leucémie monocytique aigüe), M6 (leucémie érythroïde aigüe) ou M7 (leucémie mégakaryoblastique aigüe) du système franco-américano-britannique (FAB).
Patent CA-3189047-A1 (CA)
Inventor: LEE WHEE SEONG
IPC: C07D471/04
Filed: 2021-08-13
Abstract: La présente invention concerne un composé d'imidazolquinoline ou de benzoindazolone ou un sel, hydrate, solvate, énantiomère, diastéréoisomère, tautomère ou médicament précurseur pharmaceutiquement acceptable de celui-ci ; une utilisation de celui-ci pour la prévention et le traitement d'une maladie inflammatoire ; et un intermédiaire pour sa préparation. Le composé selon la présente invention est utilisé en tant que substrat de NQ01 pour activer la réaction d'oxydoréduction de NQO1, ce qui permet d'empêcher l'expression et l'activité de cytokines inflammatoires, et en tant que tel, peut être utilisé pour prévenir ou traiter des maladies associées à l'activité de NQ01.
Patent CA-3190226-A1 (CA)
Inventor: AMBRUOSI ALESSANDRA
IPC: A61K9/16
Filed: 2021-09-15
Abstract: La présente invention concerne une préparation pharmaceutique solide de 8-(1,3-Diméthyl-1H-pyrazol-4-yl)-1-(Sa)-(3-fluoro-5-méthoxy-pyridin-4-yl)-7-méthoxy-3-méthyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one, son procédé de fabrication, ainsi que ses utilisations médicales.
Patent CA-3190712-A1 (CA)
Title: System and method for delivering a consumable commodity
Inventor: RIVARD PIERRE
IPC: F17C7/00
Filed: 2015-09-30
Abstract: A system is provided for delivering a consumable commodity, the system having at least one guide, a transportation vehicle, a destination site, and a mobile storage tank for storing the commodity, the tank having a low friction device operable to be displaced along the at least one guide, and the at least one guide providing a path between the transportation vehicle and the destination site for displacing the mobile storage tank between the transportation vehicle and destination site along the at least one guide.