baber/WOPTO huggingface dataset:
Patent IL-72417-A0 (IL)
Title: Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them
IPC: C07D233/34
Filed: 1984-07-16
Abstract: Object of the present invention are new pharmacologically active amidine derivatives of 2-substituted 4-phenylimidazole of formula 
<CHEM>
 in which R representa a linear or branched alkyl group, a hydroxy group, a C1-3 alkoxy group, a mercapto group, C1-3 alkylthio group, a halogen atom, a C1-3 alkylsulfinyl or alkylsulfonyl group, a sulfamoyl group, an amino group which may be substituted by one or two alkyl groups having 1 to 3 carbon atoms, an acylamino group or a phenyl group; R1 and R2, which may be the same or different, represent a hydrogen atom or an alkyl group; R3 represents a linear or branched alkyl group containing optionally one heteroatom such as an oxygen, a sulphur or a nitrogen atom, an alkenyl group, an alkynyl group, a cyano group, an aryl or an aralkyl group optionally substituted, a cycloalkyl or cycloaliphatic alkyl group, a substituted or unsubstituted heterocyclilalkyl or heterocyclic group; R4 represents a hydrogen atom, a C1-3 alkyl or alkoxy group, a halogen atom, a cyano or carbamoyl group, tautomeric forms thereof and acid addition salts thereof. 
<??>Processes for the preparation of the compounds of formula (1) and their intermediates as well as the pharmaceutical compositions containing them are also object of this invention. 
<??>The new compounds are H2-receptor blocking agents which inhibit the gastric acid secretion and are useful antiulcer agents.
Patent IL-84407-A0 (IL)
Title: Tetrahydronaphthalene derivatives,their manufacture and pharmaceutical compositions containing them
IPC: A61P9/08
Filed: 1987-11-09
Abstract: Compounds of the formula    <IMAGE>  I  wherein R is lower-alkyl, R1 is halogen, R2 is C1-C12-alkyl, R3 is hydroxy, lower-alkoxy, lower-alkyl-carbonyloxy, lower-alkoxy-lower-alkylcarbonoyloxy, lower-alkylaminocarbonyloxy, arylaminocarbonyloxy or aryl-lower alkylaminocarbonyloxy, X is C1-C18-alkylene which optionally can be interrupted by 1,4-phenylene or interrupted or lengthened by 1,4-cyclohexylene, A is di- or tri-substituted 2-imidazolyl attached via an ethylene group or a substituted or unsubstituted heterocycle selected from the group consisting of benzimidazolyl, benzimidazolonyl, imidazo[4,5-c]pyridinyl, imidazo[4,5-c]pyridinonyl, benzthiazolyl, benzodiazepine-2,5-dion-1-yl and pyrrolo[2,1-c]-[1,4]benzodiazepine-5,11-dion-10-yl and n is the number 0 or 1, in the form of racemates and optical antipodes, as well as N-oxides and pharmaceutically usable acid addition salts thereof. The compounds of formual I have a pronounced calcium-antagonistic and anti-arrhythmic activity and can accordingly be used as medicaments, especially for the control or prevention of angina pectoris, ischaemia, arrhythmias, high blood pressure and cardiac insufficiency.
Patent IL-87230-A0 (IL)
Title: High density tungsten-nickel-iron-cobalt alloys and processes for the preparation thereof
IPC: C22C1/04
Filed: 1988-07-27
Abstract: A process of making high density alloys containing about 85 to 98 weight percent tungsten and the balance of the alloy being substantially a binder of nickel, iron and cobalt, and wherein all cobalt is present in an amount within the range of about 5 to 47.5 weight percent of the binder, which comprises blending powders of the tungsten, nickel, iron and cobalt into a homogenous composition,     compacting the homogenous composition into a shaped article, heating the shaped article to a temperature and for a time sufficient to sinter the article, subjecting the sintered article to a temperature sufficient to enable the intermetallic phase formed at the matrix to tungsten interface to diffuse into the gamma austenitic phase whereby the alpha tungsten/gamma austenite boundaries are substantially free of such intermettalic phase,     quenching the article, and swaging the article to a reduction in area of about 5 to 40 percent,  the article having improved mechanical properties, including improved tensile strength and hardness while maintaining suitable ductility for subsequent working thereof.
Patent IL-89695-A0 (IL)
Title: Controlled release pharmaceutical preparation and its production
IPC: A61K9/50
Filed: 1989-03-21
Abstract: Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a hydrophobic polymeric substance and a hydrophilic polymeric substance, the core being coated with the porous film. Also disclosed is a method for producing the same.
Patent IL-95581-A0 (IL)
Title: Benzoylguanidines,a process for their preparation,their use as medicaments and medicaments containing them
IPC: C07D295/22
Filed: 1990-09-04
Abstract: Benzoylguanidines of the formula I  (* CHEMICAL STRUCTURE *) (I) where R(1) or R(2) is equal to R(6)-S(O)n- or R(7)R(8)N-O2S- and the other substituent R(1) or R(2) is in each case equal to H, F, Cl, Br, I, alkyl, alkoxy or phenoxy, R(6)-S(O)n or R(7)R(8)N- and R(6) is equal to alkyl, cycloalkyl, cyclopentylmethyl, cyclohexylmethyl or phenyl, R(7) and R(8) are equal to alkyl or phenylalkyl or phenyl, and in which R(7) and R(8) may also together be a C4-C7 chain, and in which R(7) and R(8), together with the nitrogen atom to which they are bonded, may be a dihydroindole, tetrahydroquinoline or tetrahydroisoquinoline system, and where R(3), R(4) and R(5) are equal to hydrogen or alkyl, or R(3) and R(4) are together an alkylene chain or R(4) and R(4) are together an alkylene chain, and where n is equal to zero, 1 or 2 and their pharmaceutically tolerable salts are outstanding antiarrhythmics.
Patent AU-PO946297-A0 (AU)
Title: Ion exchange
IPC: B01J39/19
Filed: 1997-09-25
Abstract: An ion exchange material comprising a superabsorbent polyurethane foam having an ion exchange medium contained therein. The ion exchange may be used in a process for the extraction of metal anions and cations from solutions and/or slurries including the steps of: (a) contacting a metal ion-containing solution with an ion exchange material comprising a superabsorbent polyurethane foam having an ion exchange medium contained therein; (b) separating the ion exchange material from the solution and/or slurry; and (c) recovering the sorbed metal ions from the ion exchange medium.
Patent FI-20031206-A0 (FI)
Inventor: OKSANEN PEKKA
IPC: B65G1/04
Filed: 2003-08-27
Abstract: A method for moving loads (P), especially cylindrical objects, such as web product rolls, in a sorted manner into a storage location (5), where the loads are brought and stored and from where the loads are moved out in a horizontal position on a transfer car for further treatment. At least one load (P) or a combination of several loads arranged in succession at a time is moved from a supply location (3, 4) into the storage location (5) and/or from the storage location on a transfer car (2) in such manner that the loads (P) are moved onto the transfer car (1) substantially in their longitudinal direction and correspondingly left in the storage location (5) in longitudinal orientation. <IMAGE>
Patent FI-20090055-A0 (FI)
Inventor: HAWKINS GIOVANNI
IPC: B66B/
Filed: 2009-02-16
Abstract: The invention relates to an arrangement for reducing vibration and noise caused by the hoisting machine of an elevator, said elevator comprising at least a hoisting machine (3) fitted on a mounting base (9,12), a drive sheave (4) connected to the hoisting machine (3), measuring means (7, 7') for the measurement of vibration and at least one functional element (6) for damping vibration. The rigidity of each functional element (6) is adapted to be varied on the basis of the measurement results obtained from the measuring means (7, 7').
Patent FI-20105691-A0 (FI)
Inventor: MAEKIVUOKKO HARRI
IPC: C12M/
Filed: 2010-06-15
Abstract: An in-vitro solution for simulating the growth of microbes in the presence of mammalian cells is disclosed. A layer of mammalian cells is held in a cell culture well (W1)in the presence of growth medium. A circulation unit (U1)is configured to circulate,at least a part of growth medium and microbes discarded via outlet means (O1-1) from the cell culture well (W1), back to the cell culture well (W1) via inlet means (I1-1), such that a part of the discarded growth medium is replaced with fresh growth medium. A control unit (E1)is configured to control the operation of the circulation unit (U1) based on a pH measurement carried out in the growth medium, such that the conditions in the cell culture well (W1) are kept non-toxic to the mammalian cells.
Patent IL-103087-A0 (IL)
Title: Antibiotic ll-e19020 alpha 1
IPC: C07H7/02
Filed: 1992-09-07
Abstract: The invention provides an antibiotic designated LL-E19020 Alpha1 which is derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036.
Patent IL-103962-A0 (IL)
Title: Novel trans cyclopentanyl purine analogs useful as immunosuppressants
IPC: C07D473/32
Filed: 1992-12-03
Abstract: This invention relates to novel trans cyclopentanyl purine analogs of the formula (1) <CHEM>  wherein the substituent in the 3-position on the cyclopentanyl ring is in the Trans configuration relative to the bicyclic substituent, Y3, Y5 Y7, Y8 and Y9 are each independently nitrogen or a CH group,    R is a hydrogen, a C1-C7 alkyl acyl or aryl acyl,     Q is NH2, halogen or hydrogen,     Z is hydrogen, halogen, or NH2; or a pharmaceutically-acceptable salt thereof, and to their use as immunosuppressants.
Patent IL-104818-A0 (IL)
Title: Preparation of intermediates in the synthesis of quinoline antibiotics
IPC: C07D471/04
Filed: 1993-02-22
Abstract: This invention relates to compounds of the formulae  (* CHEMICAL STRUCTURE *) (III) and  (* CHEMICAL STRUCTURE *) (IV) wherein R and X are defined as below. These compounds are useful as intermediates in the syntheses of azabicyclo quinoline carboxylic acids having antibacterial activity.
Patent IL-111615-A0 (IL)
Title: Non-peptide tachykinin receptor antagonists
IPC: A61K31/496
Filed: 1994-11-14
Abstract: This invention provides a novel series of non-peptidyl compounds which are useful in the treatment or prevention of a physiological disorder associated with an excess of tachykinins. This invention also provides methods for the treatment of such physiological disorders as well as pharmaceutical formulations which employ these novel compounds.
Patent IL-115313-A0 (IL)
Title: Low calorie food products
IPC: A23G1/00
Filed: 1995-09-14
Abstract: PCT No. PCT/IB95/00308 Sec. 371 Date Jul. 15, 1997 Sec. 102(e) Date Jul. 15, 1997 PCT Filed Apr. 28, 1995 PCT Pub. No. WO96/08976 PCT Pub. Date Mar. 28, 1996Low calorie food products that contain highly crystalline bulking agents that impart improved texture and mouthfeel to the food products are described. The food products contain 1,4-anhydroglucitol or 1,4-anhydrogalactitol and a food ingredient. A method of preparing 1,4-anhydro-DL-galactitol comprising heating galactitol in a water-immiscible, high-boiling, reaction-inert medium in the presence of a mineral acid is also described.
Patent IL-125048-A0 (IL)
Title: Barbituric acid derivatives processes for their production and pharmaceutical agents containing these compounds
IPC: A61K31/515
Filed: 1996-12-20
Abstract: PCT No. PCT/EP96/05766 Sec. 371 Date Aug. 26, 1998 Sec. 102(e) Date Aug. 26, 1998 PCT Filed Dec. 20, 1996 PCT Pub. No. WO97/23465 PCT Pub. Date Jul. 3, 1997Compounds of formula I, useful as matrix metalloprotease inhibitors, wherein X, Y and Z are each oxygen; R1 is selected from the group consisting of (a) n-octyl, (b) n-decyl, (c) biphenyl and (d) (4-phenoxy)phenyl, wherein the terminal monocycle for moieties (c)-(d) is unsubstituted or substituted by a substituent selected from the group consisting of -NH2, -NO2, -SO2NH2, -SO2CH3, acetyl, hydroxy, methoxy, ethoxy, cyano and halogen; R2 and R3 are each hydrogen; and R4 and R5, together with the nitrogen atom to which they are bound, form a piperazinyl or piperidyl ring, wherein the piperazinyl ring is substituted in the 4-position with a substituent selected from the group consisting of (a) a 6-membered aromatic monocycle having 0, 1 or 2 nitrogen atoms and the remainder of the atoms in the monocycle being carbon and (b) hydroxy-C1-C6 alkyl, wherein the monocycle is unsubstituted or substituted by a substituent selected from the group consisting of halogen, -NH2, -NO2, -SO2NH2, -SO2CH3, acetyl and cyano.
Patent IL-128929-A0 (IL)
Title: Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase
IPC: A61K31/5377
Filed: 1997-09-11
Abstract: Novel compounds of formula (1.0) are disclosed. Compounds of formula (1.0) are represented by the compounds of formulas (1.4) or (1.5) wherein R<1>, R<3> and R<4> are each independently selected from halo. W represents a group selected from (a), (b), (c) or (d). Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.
Patent IL-130358-A0 (IL)
Title: Adaptable frame carrier with triaxial freedom of movement for couches and seats
IPC: A47C9/00
Filed: 1997-11-25
Abstract: An adaptable frame carrier with triaxial freedom of movement for couches and seats, in which the freedom of movement is achieved in the X-, Y- and Z-direction by a system of elements which can be moved relative to one another and are spring loaded, a connecting element making the moveability between the X-, Y- and Z-direction interdependent. The frame carrier having at least one dome-shaped rolling body (3, 8) which rolls along a pressure-resistant rolling plate (2) in the X- and Y-direction, and two cylinders (6, 7) which slide one into the other and are supported against each other in the Z-direction by a compression spring (4). One of the cylinders (7) which slide one into the other being connected in a spring-loaded and hinged manner to the frame (18) of the couch or seat via a frame connection plate (13).
Patent IL-131414-A0 (IL)
Title: Apparatus and method for removing tops or roots from crops
IPC: A01D23/04
Filed: 1999-01-13
Abstract: A machine for removing roots and tops from crops including a pair of counter-rotating rollers spaced apart so as to define a nip therebetween, and means for rotating the rollers characterized in that at least one roller is in the form of a polygonal twisted prism.
Patent IL-139767-A0 (IL)
Title: Method to agglomerate metal particles and metal particles having improved properties
IPC: H01G9/04
Filed: 1999-05-20
Abstract: A method to agglomerate metal particles such as tantalum and niobium powders is described which includes combining a volatilizable or vaporizable liquid with the particles to form wet particles; compacting the wet particles; drying the compacted wet particles to form a cake; and heat treating the cake to form the agglomerated particles. Also described are agglomerated particles obtained by this method and further, particles, preferably tantalum or niobium powder, having a flow rate of at least about 65 mg/sec and/or an improved pore size distribution, and/or a higher Scott Density. Capacitors made from tantalum powder and niobium powder are also described.
Patent IL-147286-A0 (IL)
Title: Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
IPC: C07H21/00
Filed: 2000-07-07
Abstract: Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.
Patent IL-150584-A0 (IL)
Title: Method for producing 2-(1,2,4-triazol-1-yl)-ethanols
IPC: C07D521/00
Filed: 2001-01-29
Abstract: According to a novel process, microbicidally active 2-(1,2,4-triazol-1-yl)-ethanols of the formula  in which A1, A2, R1, R2, R3 and R4 are as defined in the description, can be prepared by reacting hydrazine derivatives of the formula  with N-dihalogenomethyl-formamidinium halide of the formula  in which X represents chlorine or bromine, if appropriate in the presence of a diluent.
Patent IL-150696-A0 (IL)
Title: Pharmaceutical compositions containing benzimidazole derivatives and processes for the manufacture thereof
IPC: A61K9/00
Filed: 2001-01-10
Abstract: The invention provides a solid oral pharmaceutical composition in capsule or powder dosage form comprising: 
a) omeprazole or a single enantiomer thereof, including a salt or other derivative thereof; and 
b) sodium bicarbonate;  
wherein the dosage form is not enteric coated or time-released, and the composition comprises from 7 to 25 mEq sodium bicarbonate per 20 mg omeprazole.
Patent IL-153478-A0 (IL)
Title: System for monitoring health, wellness and fitness
IPC: A61B5/00
Filed: 2001-06-13
Abstract: A detecting, monitoring and reporting system includes a sensor device which generates data indicative of physiological parameters of an individual and data derived therefrom when placed in proximity with the body. A remote central monitoring unit generates analytical status data from the data indicative of physiological parameters, the derived data, and analytical status data that has previously been generated. A data storage device stores the data received and generated by the central monitoring unit. The system includes means for establishing electronic communication between the sensor device and the central monitoring unit, and means for transmitting the data to a recipient. The sensor device may also generate data indicative of contextual parameters of the individual, which may then be used when generating the analytical status data. The system may be used for monitoring and providing feedback relating to the degree to which an individual has followed a suggested routine.
Patent IL-154142-A0 (IL)
Title: Novel amylolytic enzyme extracted from bacillus sp.a 7-7 (dsm 12368) and washing and cleaning agents containing this novel amylolytic
IPC: C12N1/21
Filed: 2001-07-19
Abstract: The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, the aforesaid can be further developed beyond the implemented fields of application for other technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of the amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
Patent IL-156347-A0 (IL)
Title: Medical device and locking mechanism therefor
IPC: A61M25/06
Filed: 2001-01-25
Abstract: A locking mechanism 10 for a medical sharp device such as a syringe assembly 62 includes a retainer part 12 for retaining a hypodermic needle 22 , and a connector part 14 . The retainer part includes lugs 46 for engagement with a recess 82 formed in a neck 70 of the syringe assembly. When a plunger 72 of the syringe assembly is pushed fully forwards, the lugs 56 of the retainer part 12 engage behind a ledge 54 of the connector part 14 and the lugs 46 disengage from the recess 82 . The plunger 72 may then be retracted, pulling the needle 22 into the barrel 64 of the assembly. The neck portion may be eccentrically mounted on the barrel and means 116,118 may be provided for preventing rotation of the plunger 72 in the barrel 64.
Patent IL-161803-A0 (IL)
Title: Multi-mode searchlight
IPC: B64D47/08
Filed: 2002-11-05
Abstract: A multi-mode visible and infrared lighthead ( 100 ) for use as a landing light or searchlight. The multi-mode lighthead incorporates a modular design wherein at least one visible light source ( 200 ) and at least one infrared diode ( 302 ) are mounted into the rear sector ( 128 ) of a housing ( 102 ). Visible or infrared light is emitted out of the front sector ( 122 ) of the housing ( 102 ). Lenses ( 308 ) are installed onto the front sector ( 122 ) of the housing ( 102 ) and sealed to protect the interior of the lighthead ( 100 ) from the elements. Alternatively, and in combination, an imaging module ( 1 ), and infrared laser ( 400 ) and/or a fixed-position searchlight with rangefinder and positioning capability is provided in the multi-mode lighthead( 100 ).
Patent IL-165299-A0 (IL)
Title: Destruction of perchlorate in ferric chloride and hydrochloride acid solution with control of temperature, pressure and chemical reagents
IPC: B01J49/00
Filed: 2003-05-28
Abstract: A method is described to decompose perchlorate in a FeCl3/HCl aqueous solution such as would be used to regenerate an anion exchange resin used to remove perchlorate. The solution is mixed with a reducing agent, preferably an organic alcohol and/or ferrous chloride, and can be heated to accelerate the decomposition of perchlorate. Lower temperatures may be employed if a catalyst is added.
Patent IL-165868-A0 (IL)
Title: Method and apparatus for hybrid decision feedback equalization
IPC: H04B7/005
Filed: 2004-12-19
Abstract: A method and apparatus for a decision feedback equalizer wherein a correction term is used to compensate for slicer errors, thus avoiding error propagation. Filter coefficients for the equalizer are selected so as to minimize a cost function for the equalizer, including a correction term as a function of the energy of the filter coefficients. The equalizer includes a coefficient generator responsive to the correction term. One embodiment estimates a transmitted symbol from a received sample as a function of Signal-to-Interference and Noise Ratio (SINR) of the received sample. The received sample is quantized and mapped to a region of a grid overlaid on the transmitted symbol constellation. The region may correspond to a symbol estimate value or may be processed further to obtain a symbol estimate value.
Patent IL-170685-A0 (IL)
Title: Protein conjugate
IPC: A61K47/48
Filed: 2005-09-06
Abstract: A protein conjugate having a prolonged in vivo half-life of a physiological activity, comprising i) a physiologically active polypeptide, ii) a non-peptidic polymer, and iii) an immunoglobulin, is useful for the development of a polypeptide drug due to the enhanced in vivo stability and prolonged half-life in blood, while reducing the possibility of inducing an immune response.
Patent IL-172442-A0 (IL)
Title: Novel rubisco promoters and uses thereof
IPC: C12N15/82
Filed: 2005-12-07
Abstract: The present invention is related to a family of novel spatiotemporally active Rubisco promoters (SEQ ID NOs: 1, 2 or 3) obtainable from light grown Brassica seedlings and capable of directing expression in cotyledons and to transgene expression in specific plant organs or at specific stages of plant development. The promoters are useful for designing DNA constructs or cassettes, comprising at least one of said promoter sequences functionally fused with genes encoding the desired gene products. Seeds from transformed homologous and heterologous plants and from subsequent generations of the transformed plants are collected and used for efficient production of gene products, particularly in contained conditions.
Patent IL-180440-A0 (IL)
Title: Compact source with very bright x - ray beam
Filed: 2006-12-28
Abstract: The device has two cooling elements (8, 9) fixed to a vacuum pump stator (1b) or a sealed peripheral casing (1f) opposite to one of two main radial faces (2b, 2c) of a rotary anode (2) for absorbing radiated heat energy emitted by the anode during operation. The rotary anode is provided in a vacuum enclosure (7), driven in rotation around a rotation axis and integrated to a rotor (1a) of a vacuum pump (1). The anode receives, on its periphery (2a), electron flow (4) from a cathode (3) to emit X-rays (6) towards an outlet (11).