baber/WOPTO huggingface dataset:
Patent CA-2371391-A1 (CA)
Inventor: NADLER JERRY L
IPC: C07D473/06
Filed: 2000-04-28
Abstract: Pentoxifylline, pioglitazone and metformin have been found to inhibit the nonenzymatic glycation of proteins which often results in formation of advanced glycation endproducts and crosslinks. The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood and in the intracellular environment such as occurs with diabetes. The structural and functional integrity of the affected molecules become perturbed by these modifications and can result in severe consequences. The compounds of the present invention can be used to inhibit this process of nonenzymatic glycation and therefore to inhibit some of the ill effects caused by diabetes or by aging. The compounds are also useful for preventing premature aging, rheumatoid arthritis, Alzheimer's disease, uremia, neurotoxicity, atherosclerosis ans spoilage of proteins in food and can prevent discoloration of teeth.
Patent CA-2371885-A1 (CA)
Title: Electrocoating compositions containing high aspect ratio clays as crater control agents
Inventor: KAYLO ALAN J
IPC: C09D175/04
Filed: 2000-02-22
Abstract: Provided are cationic electrodepositable compositions comprised of an acidified aqueous dispersion of (a) an ungelled cationic resin, (b) a curing agent having at least two functional groups which are reactive with (a), and (c) an exfoliated silicate derived from a layered silicate. These compositions exhibit improved crater control. Also provided is a method of electrocoating conductive substrates using such compositions.
Patent CA-2372864-A1 (CA)
Inventor: STOA PETTER
IPC: G01L5/10
Filed: 2000-04-27
Abstract: System for monitoring high-tension cables (1) in air stretches as well as a use of the same. The system comprises at least one optic fibre (3) fastened to the high-tension cable (1), said optic fibre comprising at least one Bragg grating (4) with known reflection characteristics, a light source (6) for emitting light within a known range of wavelengths into the optic fibre, and measuring devices (7) for detection of light reflected from the Bragg gratings (4) in the fibre (3) and for recognizing light reflected from each Bragg grating (4) based on their known reflection characteristics.
Patent CA-2374183-A1 (CA)
Inventor: ALBIERO FRANCESCO
IPC: E02B7/38
Filed: 2002-03-01
Abstract: The invention relates to a safety edge for horizontally pivoted rolling gates actuated by a motor unit. It consists of a profile (11) made of rubber or other soft flexible material and having a base (14) for its application to a rolling date, and of two electrical conductors (15,16) extending longitudinally into the soft profile, parallel and normally separate from one another. The conductors move closer in the presence of a deforming thrust on said profile, to come into contact and enable an electrical circuit to send a signal for stopping the rolling gate motor unit.
Patent CA-2374329-A1 (CA)
Title: Enterprise contact server with enhanced routing features
Inventor: GOSS RAYMOND G
IPC: H04L29/06
Filed: 2000-05-22
Abstract: The present invention is an Enterprise Contact Server (100) that enables customers to submit call-back requests to agents (13) located at any one of a plurality of call centers (116) via the Internet (32), or virtually any other communications technology available.
Patent CA-2374496-A1 (CA)
Title: Hydrofoil apparatus
Inventor: SHATTOCK BERNARD AUBREY
IPC: B63B21/66
Filed: 2000-06-05
Abstract: Hydrofoil apparatus comprising a first hydrofoil member (1) having chord and span dimensions and positive hydrodynamic pitching moments, a second hydrofoil member (2) having chord and span dimensions and positive hydrodynamic pitching moments, connection means (3) for connecting the first and second hydrofoil members (1, 2) together such that they are able to articulate about the connection means (3), at least first and second bridle members (4, 6) which are for enabling the hydrofoil apparatus to be towed and are such that the first bridle member (4) is articulately attached at one end (5) to an outer end portion of the first hydrofoil member (1) thereby forming a first pitching axis (BC), the second bridle member (6) is articulately attached at one end (7) to an outer end portion of the second hydrofoil member (2) thereby forming a second pitching axis (DE), the first and second pitching axes (BC, DE) forming an angle such that a component of hydrodynamic lift generated by the first hydrofoil member (1) and a component of hydrodynamic lift generated by the second hydrofoil member (2) act in parallel directions away from each other, and regulation means (8, 11) by which the angle formed by the first and second pitching axes is regulated.
Patent CA-2381631-A1 (CA)
Title: Sealing label
Inventor: KAWASHIMA YOICHI
IPC: B65D41/62
Filed: 2000-08-14
Abstract: For sealing a container (2) consisting of a barrel portion (3) and a cap portion (4) threaded and tightened on the barrel portion, the sealing label (1) includes a lower portion (1A) for substantially wrapping the barrel portion and an upper portion (1B) for substantially wrapping the cap portion. The sealing label includes horizontal perforations (10) consisting of cut segments (11) and uncut segments (12; 13) extending along a border between the upper portion (1B) and the lower portion (1A); a knob portion (1a) disposed at an edge of the upper portion; and inclined perforations (20) consisting of cut segments (21) and uncut segments (22) extending obliquely in the upper portion from the knob portion to the horizontal perforations.
Patent CA-2382414-A1 (CA)
Title: Method of surface modifying a medical tubing
Inventor: DING YUAN-PANG S
IPC: C08J7/043
Filed: 2000-08-31
Abstract: The present invention provides a method for fabricating a medical tubing. The method includes the steps of: (1) providing a material selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the ethylene copolymer are obtained by copolymerizing ethylene with a comonomer selected from the group consisting of lower alkyl olefins, lower alkyl olefins, lower alkyl esters of a carboxylic acid and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene each have from 3-18 carbons, or blends thereof; (2) providing an extruder with an extrusion die; (3) extruding the material into a medical tubing; (4) providing a surface modifier solution; (5) preheating the surface modifier solution to a temperature within the range of 50-80 ~C; and (6) applying the preheated solution onto the tubing as it exits the extrusion die when the tubing is in a molten state or a semi-molten state.
Patent CA-2382793-A1 (CA)
Title: Toit de bac de compostage
Inventor: TSCHUDI JEAN-PIERRE
IPC: C05F17/02
Filed: 2001-06-23
Abstract: L'invention concerne un ensemble toit comportant des pans de toit (7, 8), destiné à des bacs de compostage (1, 2) qui sont exploités avec des chargeuses pelleteuses. Cet ensemble assure une meilleure hygiène de l'environnement grâce à un élément d'étanchéité périphérique (9, 10). Le condensat est réacheminé à son lieu d'origine par l'intermédiaire d'un stratifié de recouvrement structuré (20) comportant des parties saillantes de type arête (22, 23) qui forment une structure réticulaire sur le côté inférieur de la bâche semiperméable (21), ce qui permet d'augmenter la teneur en humidité et d'améliorer la qualité du compost.
Patent CA-2384128-A1 (CA)
Inventor: SCHMIDT DALE C
IPC: C08G73/02
Filed: 2000-09-01
Abstract: A solution and a stable aqueous dispersion of an acid salt of a polyetheramine can be prepared by at least partially neutralizing the polyetheramine with an acid. The solution and dispersion are useful as a coating, particularly in applications where it is desirable to have a barrier against small molecules.
Patent CA-2384940-A1 (CA)
Title: Hanger and pin assembly for displaying merchandise
Inventor: SWOPES CLETIS F
IPC: A47F5/00
Filed: 2001-07-31
Abstract: A hanger and pin assembly (15) for displaying merchandise, having a plurality of elements (11a, 11b, 11c, and 11d) has, a generally planar member (16) and a pin member (18) disposed for operative engagement with one end of the planar member (16) for removably connecting the plurality of elements of the merchandise to the hanger and pin assembly (15) to form a modular unit (10a). An annular section (13) at the opposite end of the planar members defines a sized opening (13a) for removably mounting the merchandise at a point of sale, and spaced protuberances (27a and 27b) between the annular section (13) and the pin member (18), engaged to stabilize the merchandise in assembled position. An alternate form of the hangar and pin assembly (215) has an arcuate section (213a) to define a passage in communication with the sized opening (213).      A laterally extending support plate (213) can be provided in lieu of the spaced protuberances to stabilize the merchandise being displayed.
Patent CA-2385283-A1 (CA)
Title: Apparatus and method for determining oil well effluent characteristics for inhomogeneous flow conditions
Inventor: LYNCH FRANK J
IPC: G01N23/06
Filed: 2000-10-04
Abstract: An apparatus and method for determining the phase volume fractions for a multiphase oil well effluent is disclosed. The apparatus measures multiple energy gamma ray attenuations through the effluent mixture, and the method determines the phase volume fractions from these measurements when the mixtu re is under inhomogeneous flow conditions. The apparatus includes a pipe sectio n with a Venturi (100) through which the mixture flows. A source of radiation transmits rays (260) at two or more energy levels through the mixture. A sol id state detector (170) measures the transmitted attenuation count rates. A low  absorption window of a truncated cone shape is preferably incorporated in li eu of the pipe wall in the area of the detector. The method comprises measuring  ray attenuation, in the two-energy example, at one high energy emission line , to differentiate between the gas and liquid components, and at a relatively lower energy emission line, to differentiate between the oil and water phase s within the liquid component.
Patent CA-2385986-A1 (CA)
Title: New use of modafinil and the d/l enantiomers for enhancing sexual function in mammals
Inventor: FU JUNCHANG
IPC: A61P15/08
Filed: 2000-04-12
Abstract: This invention relates to new uses of Modafinil and its D/L enantiomers, particularly the new uses in the pharmaceutical preparation field. This invention provides new uses of Modafinil and its D/L enantiomers in preparing the medicine for increasing and enhancing the quantity and quality of normal spermatozoa in male mammals, the medicine for enhancing the pregnant capacity in female mammals, the medicine for treating infertility, subfertility and sex dysfunction in male and female mammals, and the medicine for enhancing the sexual function in mammals.
Patent CA-2388546-A1 (CA)
Inventor: FORD DAVID F
IPC: A47J31/44
Filed: 2001-06-06
Abstract: An apparatus (22) is used for rinsing or cleaning a pair of reservoirs (24,26) in the apparatus (22). The apparatus (22) includes a housing (68), a fluid reservoir associated therewith, a controller in communication with the fluid reservoir, structure for selectively passing fluid from the fluid reservoir to at least one outlet on the housing, and first and second reservoirs (24,26) mounted in the housing (68). A holder (20) can be mounted on said housing (68). The holder (20) includes a body (28), a drain hole (50) provided therethrough, and a conduit (45) provided therethrough. The conduit (45) is spaced from the drain hole (50). When the holder (20) is mounted on the housing (68), the drain hole (50) is positioned over one of the reservoirs and the conduit (45) is located over the other of the reservoirs. Fluid simultaneously flows from the water reservoir to the holder (20) through the conduit (45) into the other reservoir.
Patent CA-2390800-A1 (CA)
Inventor: EDWARDS STUART D
IPC: A61F2/958
Filed: 2001-01-24
Abstract: A method and system for shrinking dilatations of a body, removing excess, weak or diseased tissues, and strengthening remaining tissues of the lumen walls. A  catheter is disposed near the dilatation and fixed in position by inflatable occlusion balloons. Body fluids present in the occluded dilatation are evacuated and treatment fluid is exuded under pressure into the dilatation.  Pressure is maintained by the treatment fluid while energy is applied by the catheter to heat the treatment fluid, causing the lumen walls to absorb the treatment fluid. Additional energy is then applied so as to preferentially heat the lumen wall tissues which have absorbed the treatment fluid, while at the same time treatment fluid is circulated to cool the inner surface of the lumen walls. The dilatation is occluded, a saline solution is introduced and absorbed into the lumen-wall tissue in the occluded region of the dilatation and then heated by application of radio frequency ("RF") or other energy in order to soften only the lumen-wall tissue of the dilatation, the dilatation is shrunk by application of a chilled saline solution and a vacuum, and additional RF or other energy is emitted to ablate, further shrink, and harden only the lumen-wall tissue of the dilatation, without destroying the inner surface of the lumen or other tissues of the body beyond the lumen walls, thereby promoting the growth of epithelial cells.
Patent CA-2392336-A1 (CA)
Title: Pipe and conduit coupling assembly
Inventor: KIELY KENNETH M
IPC: H02G9/06
Filed: 2002-06-28
Abstract: By providing a single, elongated, hollow, cylindrically shaped housing member and locking rings or washers mounted at the ends of the housing member, a simple, easily used, inexpensive conduit coupling and connector assembly is achieved. in one embodiment, the connector assembly is constructed for receiving the free ends of two separate and independent conduits and securely affixing the two conduits in co-axial, aligned, cooperating relationship with each other, while in an alternate embodiment, a single conduit or tubing member is securely mounted to the connector assembly for positioning the conduit or tubing member in a precisely desired location. In addition, the conduit coupling and connector assembly of the present invention may be implemented using various alternate embodiments for either the locking rings or washers or for the housing member.
Patent CA-2392545-A1 (CA)
Title: Pharmaceutical formulations for thyroid hormones
Inventor: GARAVANI ALBERTO
IPC: A61K9/28
Filed: 2002-06-28
Abstract: The present invention provides for pharmaceutical formulations based on thyroid hormones enabling a safe and stable oral administration in the framework of the strict therapeutic index prescribed in case of thyroid disorders.
Patent CA-2393479-A1 (CA)
Inventor: LANDER RUSSEL J
IPC: C12N15/10
Filed: 2000-12-21
Abstract: La présente invention se rapporte à un procédé non chromatographique d'isolement, à partir de cellules bactériennes, d'ADN plasmidique de qualité propre à un usage clinique. Les procédés décrits dans l'invention se caractérisent par un protocole économiquement avantageux et évolutif pour la purification d'ADN plasmidique de qualité propre à un usage clinique, à partie de E.coli, consistant en une précipitation de l'ADN avec du détergent CTAB, en association à une adsorption des impuretés par du silicate de calcium.
Patent CA-2394573-A1 (CA)
Inventor: SUNDARAMOORTHI RAJESWARI
IPC: A61K31/675
Filed: 2000-12-18
Abstract: This invention relates to compounds of general formula (I) in which RA, RB, RC  and RD are as defined herein, and to their preparation and use.
Patent CA-2397753-A1 (CA)
Title: Transcutaneous device for treating female urinary incontinence by sub-urethral strip
Inventor: SCETBON VICTOR
IPC: A61F2/00
Filed: 2001-01-18
Abstract: A device for treating urinary stress incontinence in women includes a flexible and elongate mechanism including a tape for supporting a urethra and a flat protective sheath enveloping the tape; and a puncturing needle with an active distal end and a proximal end connected to a first end of the flexible and elongate mechanism, wherein the proximal end of the puncturing needle is connected to a first end of the flexible and elongate mechanism by an intermediate traction element, a second end of the flexible and elongate mechanism being free. A method for treating urinary stress incontinence in a woman suffering from urinary stress incontinence is also provided including (a) forming an opening in an anterior vaginal wall; (b) creating, from two small suprapubic incisions formed in the abdominal wall, a right track and a left track from the abdominal skin to the opening formed in the anterior vaginal wall; (c) using a needle and an intermediate traction element to follow one of the tracks and following the other track with at least a needle; (d) verifying by cystoscopy that the paths of the tracks are outside the bladder and the urethra; (e) using a support tape surrounded by a plastic sheath to follow the tracks by passage under an inferior surface of the urethra; (f) adjusting a loop formed by the sheathed tape under the inferior surface of the urethra; (g) removing the sheath by pulling the sheath toward the outside of the woman's body through the small suprapubic incisions; and (h) leaving the tape implanted from the first to the second incision and around the urethra to support the urethra.
Patent CA-2398667-A1 (CA)
Inventor: DAVYDOV VALENTIN GEORGIJEVICH
IPC: C22C21/08
Filed: 2001-12-14
Abstract: The invention relates to chemical compositions of alloys, particularly naturally hard semi-finished product alloys which should be used in said for m as material for semi-finished products. The invention also relates to a naturally hard aluminium alloy for semi-finished product structures which is  made of magnesium, titanium, beryllium, zircon, scandium and cerium and additionally manganese, copper, zinc and an element group containing iron an d silicon, whereby the ratio of iron to the silicon ranges between 1 and 5. Th e composition of the aluminium alloy is (in wt. %): magnesium 5.0-5.6; titaniu m 0.01-0.05; beryllium 0.0001-0.005; zircon 0.05-0.15; scandium 0.18-0.30; cerium 0.001-0.004; manganese 0.05-0.18; iron 0.05-0.18; zinc 0.05-0.15; the  element group containing iron and silicon 0.04-0.24 and the rest being aluminium.
Patent CA-2399123-A1 (CA)
Inventor: HU SHIQING
IPC: A61K9/70
Filed: 2001-01-20
Abstract: A medicine for treating aseptic inflammation is disclosed in the invention, in which ANEMONIN is contained as an effective component, especially the use of  compound ANEMONIN in the treatment of aseptic inflammation is disclosed in t he invention. The effective component ANEMONIN contained in the medicine of the  invention can be extracted and isolated from natural plant which contain ANEMONIN and the precursor thereof. A process for preparing extract of ANEMONIN is disclosed also. The medicine of the invention can be prepared in  the form for oral, injecting and external use, especially in the form of liquid extract, emplastrum, suppository, liniment, varnish etc. which can be  absorbed through skin.
Patent CA-2400081-A1 (CA)
Inventor: OISHI KAZUYUKI
IPC: B01J20/26
Filed: 2001-02-16
Abstract: L'invention concerne des adsorbants de substances hydrophobes, qui sont capables d'adsorber efficacement des substances hydrophobes, notamment des substances agissant comme des hormones, des hydrocarbures aromatiques polycycliques, ou des composés organiques volatiles. Lesdits adsorbants peuvent désorber lesdites substances aisément et ils ne sont pas sensibles à leur élution. L'invention concerne, en particulier, des adsorbants de substances hydrophobes, constitués de polymères réticulés préparés par réticulation par polymérisation de monomères choisis parmi les esters acryliques et les esters méthacryliques.
Patent CA-2400274-A1 (CA)
Inventor: STORER RICHARD
IPC: A61K31/575
Filed: 2001-02-19
Abstract: La présente invention concerne une méthode de traitement ou de prévention d'infections à Flavivirus à l'aide d'analogues nucléosidiques, consistant à administrer une dose thérapeutiquement efficace d'un composé représenté par la formule générale (I) ou un sel pharmaceutiquement acceptable de celui-ci à un hôte.
Patent CA-2404993-A1 (CA)
Inventor: HANSON JOEL
IPC: H04W4/12
Filed: 2001-03-20
Abstract: L'invention porte sur un procédé (Fig. 2) et sur un appareil correspondant de distribution d'un message provenant d'un demandeur se situant au niveau d'une station appelante et destiné à un demandé au niveau d'une station appelée. En réponse à une tentative vaine de communication de la station appelante à la station appelée (étape 22), le système de messagerie enregistre un message provenant de la station appelante (étape 32). Le système de messagerie tente de distribuer le message à la station appelée en déclenchant à partir du système de messagerie une communication destinée à la partie appelée (étape 38). En réponse à une distribution réussie du message, le système de messagerie avise le demandeur que le message a bien été délivré à la station appelée.
Patent CA-2410885-A1 (CA)
Title: Composition for the treatment and/or the prevention of osteoporosis and/or inflammatory joint diseases
Inventor: FROHNE MARCUS
IPC: A61K31/525
Filed: 2001-05-19
Abstract: Compositions and pharmaceutical compositions are described which comprise: a  component A comprising one or more flavonol glycosides, a component B comprising one or more tetrahydrofolic acid compounds, a component C comprising one or more calcium supplements, and a component D comprising one  or more magnesium supplements. Methods of using such compositions and pharmaceutical compositions to treat and/or prevent osteoporosis and/or an inflammatory joint disease are also described.
Patent CA-2411542-A1 (CA)
Title: Encapsulation d'adn plasmidique (lipogenesmc) et d'agents therapeutiques contenant des conjugues peptidiques a signal de localisation nucleaire/fusogenes dans des complexes ciblesde liposomes
Inventor: BOULIKAS TENI
IPC: A61P29/00
Filed: 2001-06-08
Abstract: L'invention concerne un procédé d'encapsulation de plasmides, d'oligonucléotides ou de médicaments négativement chargés dans des liposomes présentant une composition lipidique différente entre leur bicouches membranaires intérieure et extérieure et capables d'atteindre des tumeurs primaires et leurs métastases après une injection intraveineuse administrée à des animaux et à des humains. Le procédé de formulation comprend une formation de complexe entre l'ADN avec des molécules lipidiques cationiques, et des conjugués de peptides fusogènes/NLS composés d'une chaîne hydrophobe d'environ 10-20 acides aminés et contenant également au moins quatre résidus d'histidine ou NLS au niveau de leur unique extrémité. Les molécules encapsulées présentent une efficacité thérapeutique dans l'éradication d'une variété de tumeurs humaines solides comprenant, notamment, le carcinome mammaire et le carcinome prostatique. Une combinaison de plasmides, d'oligonucléotides ou de médicaments chargés négativement, associée à d'autres médicaments antinéoplasiques (le cis-platine chargé positivement, la doxorubicine) encapsulés dans des liposomes, peut présenter une valeur thérapeutique. Les combinaisons de plasmides, oligonucléotides ou médicaments chargés négativement encapsulés avec HSV-tk plus du ganciclovir encapsulé peuvent également présenter une valeur thérapeutique.