baber/WOPTO huggingface dataset:
Patent WO-2019169229-A1 (WO)
Inventor: LIU LINDA
IPC: C07K16/28
Filed: 2019-03-01
Abstract: Compositions that bind to killer cell lectin-like receptor G1 (KLRG1) or its ligands are provided. The compositions can agonize or antagonize signal transduction through KLRG1. For example, some compositions either inhibit or block signal transduction through KLRG1 while other compositions induce or enhance signal transduction through KLRG1. In some embodiments, the compositions are anti-KLRG1 antibodies, KLRG1 fusion proteins, or KLRG1 ligand fusion proteins. One embodiment provides antibodies and antigen binding fragments thereof that immunospecifically bind KLRG1 and block, inhibit or reduce signal transduction through KLRG1. In another embodiment, the antibodies specifically bind to human KLRG1 under physiological conditions. In certain embodiments, the antibodies bind to KLRG1 that is arrayed on the surface of a cell; arrayed on the surface of a cell at an endogenous concentration; arrayed on the surface of a live cell, and inhibits or blocks interaction of KLRG1 and a ligand of KLRG1; or a combination thereof. In a preferred embodiment, the antibody or antigen binding fragment thereof binds to the extracellular domain of KLRG1 expressed on an immune cell including, but not limited to natural killer cells and T cells. Methods of using the compositions are also provided.
Patent WO-2019183241-A1 (WO)
Title: Extension de nombre de canaux logiques dans des technologies d'accès radio cellulaire
Inventor: HAMPEL KARL GEORG
IPC: H04L29/08
Filed: 2019-03-20
Abstract: Selon un aspect, la présente invention concerne des procédés, des systèmes et des supports lisibles par ordinateur permettant d'ajouter un en-tête d'extension à un sous-en-tête de commande d'accès au support (MAC), l'en-tête d'extension comprenant des informations relatives à une extension d'une plage de canaux logiques, d'indiquer l'ajout de l'en-tête d'extension par un indicateur dans le sous-en-tête de MAC, et de transmettre le sous-en-tête de MAC.
Patent WO-2019204025-A1 (WO)
Title: Near-eye display system with air-gap interference fringe mitigation
Inventor: TAMMELA SIMO KAARLO TAPANI
IPC: G02B27/01
Filed: 2019-04-02
Abstract: A near eye display system includes a waveguide display that presents to the eyes of a viewer mixed-reality or virtual-reality images. The waveguide display includes two or more waveguide plates that are stacked over one another with an air gap between them. The waveguide plates are tilted so that they are not parallel to one another. In this way the spacing or air gap between the waveguide plates varies across the area of the plates. Because of this variation in the size of the air gap interference fringes that would appear in the output image because of constructive and destructive interference between transmitted and reflected light beams are reduced in intensity.
Patent WO-2020214152-A1 (WO)
Inventor: FATTAL DAVID A
IPC: G02B30/00
Filed: 2019-04-15
Abstract: A static multiview display and method of static multiview display operation provide a static multiview image using diffractive gratings to diffractively scatter light from guided light beams having different radial directions. The static multiview display includes a light guide configured to guide plurality of guided light beams and a light source configured to provide the guided light beam plurality having the different radial directions. The static multiview display further includes a plurality of diffraction gratings configured to provide from a portion of the guided light beams directional light beams having intensities and principal angular directions corresponding to view pixels of the static multiview image. The static multiview image has an arrangement of views configured to provide diagonal parallax that may facilitate viewing from a diagonal direction relative to the static multiview display.
Patent WO-2019204634-A1 (WO)
Title: Rap1-gtp, rac1-gtp and fms-like tyrosine kinase 3 ligand (flt3-l) as biomarkers for early detection of sepsis
Inventor: WANDINGER-NESS ANGELA
IPC: C12Q1/18
Filed: 2019-04-18
Abstract: The present invention is directed to the discovery that RapI-GTP, Racl-GTP and Flt3-L can be used as Biomarkers for the early detection of sepsis in patients suspected of a bacterial infection which presents as sepsis or is likely to produce sepsis. In particular, the present invention is directed to methods, assays and kits which may be used to distinguish sepsis (infection) from systematic inflammatory response caused by sterile inflammation in trauma patients. The method may he used to diagnose bacteria infection and/or sepsis and monitor therapy of a patient to allow modification of treatment and/or cessation of treatment.
Patent WO-2019213100-A1 (WO)
Title: Power infrastructure security system
Inventor: KOSTAN DEAN A
IPC: G06F21/46
Filed: 2019-04-30
Abstract: A distributed computing architecture is provided that decentralizes consensus with a continuously growing list of records (blocks), which are linked and secured using secure cryptography layered over stored and generated energy system management techniques. Data is stored in a nested contiguous arrangement of these blocks, and once a secure password is recorded, the data in any given block cannot be altered retroactively without the alteration of subsequent blocks, requiring the cooperation of the network majority.
Patent WO-2020222845-A1 (WO)
Title: External module for network connection to programmable logic controller (plc) backplane
Inventor: CLAUSSEN HEIKO
IPC: H04L29/06
Filed: 2019-05-02
Abstract: Examples of techniques for an external module for use in conjunction with a programmable logic controller (PLC) backplane are described herein. An aspect includes a connector configured to connect the external module to a backplane of the PLC. Another aspect includes a PLC monitoring module configured to receive data from the backplane of the PLC. Yet another aspect includes a data port, wherein the external module is configured to send data from the backplane of the PLC to a cloud server via the data port on the external module.
Patent WO-2019217748-A1 (WO)
Title: Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
Inventor: D'AGOSTINO JEFFREY A
IPC: A61L27/00
Filed: 2019-05-09
Abstract: A composite comprising: a barrier, said barrier being configured to selectively pass water, and said barrier being degradable in the presence of water; a matrix material for disposition within said barrier, wherein said matrix material has a flowable state and a set state, and wherein said matrix material is degradable in the presence of water; and at least one reinforcing element for disposition within said barrier and integration with said matrix material, wherein said at least one reinforcing element is degradable in the presence of water, and further wherein, upon the degradation of said at least one reinforcing element in the presence of water, provides an agent for modulating the degradation rate of said matrix material in the presence of water.
Patent WO-2019226432-A1 (WO)
Title: Liquid lenses and methods of manufacturing liquid lenses
Inventor: ANZLOWAR MICHAEL
IPC: G02B26/00
Filed: 2019-05-15
Abstract: A method of fabricating a liquid lens or an array of liquid lenses, and the corresponding liquid lens or array of lenses is disclosed. The method includes patterning an insulative layer (132) by photolithographic techniques to expose a portion of the conductive layer (124) and a portion of the insulative layer (132) having a surface energy below 40 mJ/m 2 . In further embodiments, the liquid lens includes an interface (110) forming a lens between a polar liquid (106) and a non-polar liquid (108) disposed within a cavity (104). The interface intersects a surface of the insulative layer (132) having a surface energy below 40 mJ/m 2 .
Patent WO-2019236894-A1 (WO)
Title: Detecting suitability of machine learning models for datasets
Inventor: GHANTA SINDHU
IPC: G06K9/62
Filed: 2019-06-06
Abstract: Apparatuses, systems, program products, and method are disclosed for detecting suitability of machine learning models for datasets 208, 210. An apparatus includes a training evaluation module 302 configured to calculate a first statistical data signature for a training data set 210 of a machine learning system using one or more predefined statistical algorithms. An apparatus includes an inference evaluation module 304 configured to calculate a second statistical data signature for an inference data set 208 of a machine learning system using one or more predefined statistical algorithms. An apparatus includes a score module 306 configured to calculate a suitability score describing the suitability of a training data set 210 to an inference data set 208 as a function of a first and a second statistical data signature. An apparatus includes an action module 308 configured to perform an action related to a machine learning system in response to a suitability score satisfying an unsuitability threshold.
Patent WO-2020013971-A1 (WO)
Title: Plug retention power outlet wall plate
Inventor: CYZEN KEITH
IPC: H01R13/639
Filed: 2019-06-20
Abstract: Power outlet wall plates having retention components are described herein that are configured to be mounted around power outlets to thereby retain power cords in electrical engagement with sockets of the power outlets. The retention components can be secured to the structure using any suitable mechanism, such as by using fasteners, snap fit, and so forth.
Patent WO-2020005761-A1 (WO)
Title: Luminescent material including hole and electron traps and an apparatus including such material
Inventor: MENGE PETER R
IPC: C09K11/08
Filed: 2019-06-21
Abstract: A luminescent material can include an element or an interstitial site that provides a hole trap in the luminescent material; a first dopant that provides a first electron trap in the luminescent material; and a second dopant that provides a second electron trap in the luminescent material, wherein the second dopant is a relatively shallower electron trap as compared to the first dopant. In an embodiment, a ratio of the first dopant to the second dopant is in a range of 10:1 to 100:1 on an atomic basis. In another embodiment, a ratio of the first dopant to the second dopant is selected so that luminescent material has a lower average value for a departure from perfect linearity in a range of 5 keV to 20 keV that is less to other luminescent materials of the same base compound. The luminescent material may not be a rare earth halide.
Patent WO-2020006289-A1 (WO)
Title: Systems and methods for monitoring patient muscle activity and for tracking patients with motor disorders
Inventor: CARDENAS DAMON
IPC: A61B5/00
Filed: 2019-06-27
Abstract: Systems and methods are described for analyzing patient muscle activity using electromyography. In some embodiments, systems and method may monitor a patient for abnormal muscle activity that may be indicative of one or more motor disorders. For example, an electromyography signal may be collected and automatically partitioned to create a plurality of data sets, each of the plurality of data sets including parts of a duration width. Data sets may further be scaled by calculating a ratio between muscle activity data in individual time windows of a data set and a maximum activity value for the patient. In some embodiments, scaled levels of muscle activity may be generated and compared to determine if levels of scaled muscle activity vary with duration width in a manner that is consistent with one or more motor disorders.
Patent WO-2020009950-A1 (WO)
Inventor: VAKNIN GOLAN
IPC: A61K31/00
Filed: 2019-07-01
Abstract: Des modes de réalisation de l'invention concernent des formulations comprenant du cannabidiol (CBD) et de la glucosamine (Gln). D'autres modes de réalisation de l'invention concernent des méthodes de traitement ou de prévention de l'arthrite, de l'arthrose, de la polyarthrite rhumatoïde, de l'ostéoporose, de l'ostéopénie, d'une douleur aux mâchoires, d'une douleur articulaire, d'une douleur du genou, d'une douleur dorsale, de la sclérose en plaques, de l'ostéomalacie et de la maladie osseuse de Paget, la méthode comprenant l'administration d'une formulation comprenant du cannabidiol (CBD) et de la glucosamine (Gln).
Patent WO-2020060656-A1 (WO)
Inventor: WARREN DANNY
IPC: B05D1/34
Filed: 2019-07-03
Abstract: A distribution system for delivering preheated epoxy material for spray application includes a bundle of lines that terminate on their far end in a manifold. The distribution system is uniquely constructed in a manner such that it delivers the correct materials individually to the manifold while maintaining separate flows of the materials. This separation of the materials until ready for spraying prevents mixing of the two-part epoxy which at the elevated delivery temperatures would result in early curing of the epoxy within the delivery system itself. The bundle of lines contains at least one and preferably two base epoxy delivery lines, at least one catalyst delivery line and at least one heating circuit. The manifold terminates in a static mixer that in turn delivers the mixed epoxy to a spray head for spray application to the substrate.
Patent WO-2020023202-A1 (WO)
Title: History-based affine merge and motion vector prediction
Inventor: LI GUICHUN
IPC: H04N19/176
Filed: 2019-07-08
Abstract: A method for video coding includes encoding or decoding a coding block in a current picture with an affine motion model based inter-picture prediction method in a video coding system, storing affine motion information of the coding block in a history-based motion vector prediction (HMVP) buffer that is configured for storing affine motion information candidates each including affine motion information of a processed affine-coded coding block, and constructing a motion candidate list for a current block that includes at least one candidate selected from the affine motion information candidates stored in the HMVP buffer or derived from one of the affine motion information candidates stored in the HMVP buffer.
Patent WO-2020036823-A1 (WO)
Title: Methods and apparatus for determining a crush strength of an edge
Inventor: EGBOIYI BENEDICT OSOBOMEN
IPC: G01N3/08
Filed: 2019-08-09
Abstract: A test apparatus comprises a probe movably mounted relative to a carrier. The probe comprises an end portion with a surface area of about 5 mm 2  or less. The test apparatus can be used in methods of determining a crush strength of an edge of a substrate. Methods can comprise aligning the probe with a test location of the substrate at a predetermined angle relative to a probe axis. Methods can further comprise applying a mechanical force to the test location with the probe in the direction of the probe axis. Also, methods can comprise increasing the mechanical force applied by the probe until the substrate cracks or a predefined force applied by the probe is reached. Based on the mechanical force applied by the probe, a crush strength of an edge can be determined.
Patent WO-2020036998-A1 (WO)
Title: Use of metal-core printed circuit board (pcb) for generation of ultra-narrow, high-current pulse driver
Inventor: RUBEN ERIC
IPC: H01S5/042
Filed: 2019-08-13
Abstract: A metal-core printed circuit board (MCPCB) and method of generating an ultra-narrow, high-current pulse driver with a MCPCB is provided. The MCPCB includes a rigid, metal heat sink layer and at least one electrically conductive top layer. At least one electrically insulating dielectric layer is positioned between the conductive top layer and rigid, metal heat sink layer, wherein the dielectric layer has a thickness of less than 0.007 inches.
Patent WO-2020046593-A1 (WO)
Inventor: MELNYK TOM
IPC: C09D167/02
Filed: 2019-08-15
Abstract: A process of providing a medium or high molecular weight polyester powder, the resultant polyester polymer powder, and a powder coating composition that includes such powder; wherein the process includes: providing or forming an ester oligomer; converting the oligomer to a polyester polymer by stirring at elevated pressure and elevated temperature a reaction mixture that includes the oligomer and a nonreactive carrier capable of forming an azeotrope with water and xylenes; removing water from the reaction mixture via azeotropic reflux to provide a syrup including a medium or high molecular weight polyester polymer in the nonreactive carrier; and applying a vacuum to remove the xylenes from the syrup and form a solid (which may be in the form of a powder or subsequently formed into a powder) that includes the medium or high molecular weight polyester polymer.
Patent WO-2020037164-A1 (WO)
Title: Salts and crystal forms of omecamtiv mecarbil
Inventor: MORRISON HENRY
IPC: C07C57/145
Filed: 2019-08-16
Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
Patent WO-2021034308-A1 (WO)
Title: Adaptive push streaming with user entity feedback
Inventor: AZGIN AYTAC
IPC: H04N21/845
Filed: 2019-08-16
Abstract: Adaptive push-based multi-streaming on contextualized name streams is provided by an edge server or Producer end host. Contextualized notification and update messages may be provided to carry information based on dynamic bandwidth resource availability. Receiver driven signaling towards the named stream prioritization is provided at the point of access or service point, and server-to-server signaling for dynamic bandwidth adaptation is provided at (or through) end hosts. Stream prioritization is provided at points of access through policies shared through contextualized names. Hierarchical localized edge processing for resource optimization (targeting bandwidth and/or computing resources) is also provided. Feedback is received on a regular basis to more accurately reflect the latest channel conditions (e.g., average bandwidth availability) and may also include notification from the access point to complement the user feedback. The adaptive push-based approach maximizes the decision accuracy at the end hosts given bandwidth/processing/storage constraints at the system components.
Patent WO-2020046756-A1 (WO)
Title: Contrôle d'accès pour registres de processeur basé sur des domaines d'exécution
Inventor: WALLACH STEVEN
IPC: G06F9/50
Filed: 2019-08-23
Abstract: L'invention concerne des systèmes, des appareils et des procédés associés à un processeur ayant des données d'autorisation configurables pour contrôler l'accès à un registre du processeur à partir d'instructions exécutées dans différents domaines. Des instructions peuvent être utilisées dans des domaines d'exécution prédéfinis, tels que l'hyperviseur, le système d'exploitation, l'application, etc. Différents bits d'autorisation peuvent être définis pour les instructions exécutées dans différents domaines. En réponse à une instruction exécutée dans le processeur afin de générer une demande d'accès au registre, le processeur est configuré pour déterminer s'il faut accepter ou rejeter la demande sur la base d'un bit d'autorisation fourni dans les données d'autorisation correspondant à un domaine d'exécution dans lequel l'instruction est exécutée.
Patent WO-2020076884-A1 (WO)
Inventor: DICK ROBERT
IPC: A61B5/103
Filed: 2019-10-09
Abstract: A predictive needle insertion device including a needle having a proximal needle end and a distal needle end is disclosed. A probe is movably coupled to the needle such that the probe is capable of extending beyond the distal needle end. An actuator is operable to actuate the probe to apply a mechanical force to a tissue composition. A force sensor and position sensor are configured to determine a resistive force of the tissue composition and an insertion distance of the probe, respectively. A processor is communicatively coupled to the force sensor and the position sensor, and is configured to receive sensor data indicative of a mechanical response to the mechanical force and the insertion distance of the probe, and to implement a predictive model that, based on the sensor data, predicts a forward distance to a remote position of a remote tissue portion of the tissue composition.
Patent WO-2020082011-A1 (WO)
Title: Use of mucosal transcriptomes for assessing severity of ulcerative colitis and responsiveness to treatment
Inventor: DENSON LEE
IPC: G01N33/50
Filed: 2019-10-18
Abstract: The present disclosure provides methods for assessing responsiveness or non- responsiveness to a therapeutic agent ( e.g. , steroid therapy, anti-TNF therapy or anti-integrin α4β7 therapy) in ulcerative colitis (UC) subjects based on gene signatures. The methods may further comprise identifying suitable treatment for the patient based on the gene signatures.
Patent WO-2020102548-A1 (WO)
Inventor: HOPKINS TIMOTHY P
IPC: A43B13/12
Filed: 2019-11-14
Abstract: A sole structure for an article of footwear is provided and includes a first sole plate formed at least in part from a first material having a first stiffness and including a first ground-engaging portion and a second ground-engaging portion, the first ground-engaging portion defining a first aperture extending around the second ground-engaging portion. The sole structure further including a membrane coupled to the first ground-engaging portion and the second ground-engaging portion and at least partially exposed by the first aperture, the membrane formed at least in part from a second material having a second stiffness that is less than the first stiffness.
Patent WO-2020106916-A1 (WO)
Title: Vecteurs viraux recombinants et acides nucléiques pour leur production
Inventor: THOMAS DARBY
IPC: C12N15/86
Filed: 2019-11-21
Abstract: L'invention concerne des acides nucléiques, des cassettes de transfert d'AAV et des plasmides utilisés dans la production de vecteurs viraux adéno-associés recombinés (rAAV). Les acides nucléiques, les cassettes et les plasmides décrits comprennent des séquences qui expriment un ou plusieurs transgènes ayant une efficacité thérapeutique dans l'amélioration, le traitement et/ou la prévention d'une ou de plusieurs maladies ou troubles.
Patent WO-2020142456-A1 (WO)
Inventor: STIMM DARYL
IPC: G06T3/40
Filed: 2019-12-30
Abstract: Apparatus and methods for optimized stitching of overcapture content. In one embodiment, the optimized stitching of the overcapture content includes capturing the overcapture content; producing overlap bands associated with the captured overcapture content; downsampling the produced overlap bands; generating derivative images from the downsampled overlap bands; generating a cost map associated with the generated derivative images; determining shortest path information for the generated cost map; generating a warp file based on the determined shortest path information, the generated warp file being utilized for the optimized stitching of the overcapture content. Camera apparatus and a non-transitory computer-readable apparatus are also disclosed.
Patent WO-2020146303-A1 (WO)
Title: Wiper system
Inventor: HARTMAN PHILIP
IPC: B60S1/38
Filed: 2020-01-07
Abstract: A wiper including wiper bracket which couples a wiper arm to blade carrier which carries one or more blades and includes an internal flow path which conducts fluid from a wiper bracket inlet through a hollow passage in a wiper blade carrier cover to plurality of outlets aligned with passthroughs in the blade carrier through which fluid egresses from the wiper.