baber/WOPTO huggingface dataset:
Patent CA-2207627-A1 (CA)
Title: 4-[(heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinones useful as hypolipidemic agents
Inventor: BURNETT DUANE A
IPC: A61K31/422
Filed: 1995-12-18
Abstract: 4-[(Heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinone hypocholesterolemic agents of formula (I) or a pharmaceutically acceptable salt thereof, wherein: A is optionally substituted heterocycloalkyl, optionally substituted heteroaryl, optionally substituted benzofused heterocycloalkyl, or optionally substituted benzofused heteroaryl; Ar1 is optionally substituted aryl; Ar2 is optionally substituted aryl; Q is a bond or, with the 3-position ring carbon of the azetidinone, forms the spiro group (a); and R1 is selected from the group consisting of -(CH2)9-, wherein q is 2-6 provided that when Q is a spiro ring, q can also be 0 or 1; -(CH2)e-G-(CH2)r, wherein G is -O-, -C(O)-, phenylene, -NR8- or -S(O)0-2-, e is 0-5 and r is 0-5, provided that the sum of a and r is 1-6; alkenylene; and -(CH2)f-V-(CH2)g-, wherein V is cycloalkylene f is 1-5 and g is 0-5, provided that the sum of f and g is 1-6; R5 is (b), (c), (d), (e), (f), (g) or (h); R6 and R7 are -CH2-, -CH(alkyl)-, -C(dialkyl), -CH=CH- or -C(alkyl)=CH-; or R5 together with an adjacent R6, or R5 together with an adjacent R7, form a -CH=CH- or a -CH=C(alkyl)- group; a and b are independently 0-3, provided both are not zero and when Q is a bond Ri also can be: (i), (j) or (k); M is -O- -S- -S(O)- or -S(O)2-; X, Y and Z are -CH2-, -CH(alkyl)- or -C(dialkyl); R10 and R12 -OR14, -O(CO)R14, -O(CO)OR16 or -O(CO)NR14R15; R11 and R13 are H, alkyl or aryl; or R10 and R11 together are =O, or R12 and R13 together are =O;  d is 1-3; h is 0-4; s is 0 or 1; t is 0 or 1; m, n and p are independently 0-4; provided that at least one of s and t is 1, and the sum of m, n, p, s and t is 1-6; provided that when p is 0 and t is 1, the sum of m, s and n is 1-5; and provided that when p is 0 and s is 1, the sum of m, t and n is 1-5; v is 0 or 1; j and k are independently I-5 provided that the sum of j, k and v is 1-5; Rs is H, alkyl, arylalkyl, -C(O)RI4 or -COOR14; R9 is H, alkyl, alkoxy, -COON, NO2, -NR14R15, OH or halogeno; R14 and R15 are H, alkyl, aryl and arylalkyl; R16 is alkyl or optionally substituted aryl; and R19 is H, OH or alkoxy are disclosed, as well as a method of lowering serum cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a substituted azetidinone and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.
Patent CA-2208681-A1 (CA)
Title: Drilling and pipe laying unit
Inventor: HANDFORD REGINALD R
IPC: E21B19/086
Filed: 1996-01-09
Abstract: A utility power unit (10) for underground drilling and pipe laying operations comprises a stationary frame portion (12), a movable frame portion (14) capable of performing sliding movement relative to the stationary frame portion (12) and hydraulic cylinders (44) between the stationary and the movable frame portions (12, 14) for effecting the relative movement. The movable frame portion (14) includes an attachment (36) for removably attaching a tool connecting member (38) thereto and a further attachment (48) for removably attaching a rotary drive unit (52) thereto. The invention also provides a method of directional boring along an intended underground path (62) comprising the steps of providing a machine pit (60) at a location along the intended path (62) and drilling a bore along the intended path (62) by means of directional drilling apparatus (10) which includes a stem (30) provided with a drill (68) at a forward end thereof. The bore is started from an inside wall (64) of the pit (60) and at a location beneath ground surface.
Patent CA-2211528-A1 (CA)
Title: Pushchairs
Inventor: KALLMEIER PAUL MARTIN
IPC: B62B7/14
Filed: 1996-01-24
Abstract: A pushchair having a frame and a seat moveable relative to the frame, the front end of the seat being arranged to move generally forwardly and upwardly from a sitting-up to a lying back position, with respect to the frame. The mechanism to move the seat may be any of a variety of mechanisms such as sliding mechanism or pivoting mechanisms. Automatic locking means and manually operable release means may be provided.
Patent CA-2211719-A1 (CA)
Inventor: WU TSE-CHONG
IPC: C07C45/68
Filed: 1996-02-08
Abstract: On prépare du 4-isobutylstyrène et d'autres composés oléfiniques de formule C(R¿3?)(R¿4?)=C(R¿2?)A en faisant réagir un composé organique de formule AX avec un composé vinylique substitué ou non de formule C(R¿3?)(R¿4?)=C(R¿2?)H en présence d'un catalyseur comprenant; (a) du palladium ou un sel de palladium; et (b) un liant de formule (I) dans laquelle: A est aryle, aryle substitué, hétéroaryle, hétéroaryle substitué, benzyle, benzyle substitué, vinyle, ou vinyle substitué; R¿2?, R¿3? et R¿4? sont choisis indépendamment parmi hydrogène, alkyle, cycloalkyle, cycloalkyle substitué par un alkyle, aryle, aryle substitué, alkoxy, alkylthio, hétéroaryle, hétéroaryle substitué, alcanoyle, aroyle, aroyle substitué, hétéroarylcarbonyle, hétéroarylcarbonyle substitué, trifluorométhyle et halo; X est chloro, bromo, iodo, ou diazonium; Ar est phényle, phényle substitué, naphtyle ou naphtyle substitué; R' et R'' sont choisis indépendamment parmi hydrogène, alkyle, aryle ou aryle substitué; et n est un entier de 3 à 6. Les composés oléfiniques ainsi préparés peuvent être carbonylés pour donner les composés carboxyliques correspondants.
Patent CA-2213952-A1 (CA)
Inventor: ZAMIR LOLITA
IPC: C07D305/14
Filed: 1997-08-25
Abstract: This invention relates to an improved method for isolating taxanes by using a preparative scale technique amenable to commercial production.  This method provides high yields of known taxanes in addition to new taxanes.
Patent CA-2215108-A1 (CA)
Title: Electrochemical gas sensor
Inventor: PENG WENFENG
IPC: G01N27/49
Filed: 1997-09-11
Abstract: A simple, reliable, and leak-proof electrochemical sensor for detection of toxic gases. The sensor comprises a housing having an electrochemical gas sensor cell with an electrolyte and first and second electrodes bonded to conductive plastic. Each of the first and second electrodes is a membrane formed from a fluoropolymer film having a layer adhered thereto of a catalyst-impregnated fluoropolymer.  The layers of each of said first and second electrodes are bonded to conductive plastic, and are separated by an absorbent material having an electrolyte absorbed therein.  The sensor is particularly intended for detection of carbon monoxide, but may be used to detect other gases.
Patent CA-2217949-A1 (CA)
Title: Metered-dose aerosol valve
Inventor: HISCOCKS PETER GERARD
IPC: B05B9/04
Filed: 1996-04-12
Abstract: A hand-held apparatus and method for creating an aerosolised mist of particles is described. The apparatus comprises a high pressure vessel containing a solution or suspension of the substance to be aerosolised in a high pressure liquefied gas, a manually actuatable valve and a spray nozzle. The high pressure liquefied gas is in a sub-critical state.
Patent CA-2218627-A1 (CA)
Title: High temperature superconducting thick films
Inventor: WU XIN DI
IPC: C23C14/22
Filed: 1996-04-18
Abstract: A superconducting article including a flexible polycrystalline metal substrate, a layer of an adhesion layer material upon the surface of the flexible polycrystalline metal substrate, a layer of a cubic oxide material upon the adhesion layer material, the first layer of cubic oxide material deposited by ion beam assisted deposition, a layer of a buffer material upon the ion beam assisted deposited cubic oxide material layer, and, a layer of YBCO upon the buffer material layer is provided and has demonstrated Jc's of 1.3 X 106 A/cm2, and Ic's of 120 Amperes across a sample 1 cm wide.
Patent CA-2220802-A1 (CA)
Inventor: BURNHILL STEPHEN EDWARD
IPC: H04Q9/00
Filed: 1997-11-12
Abstract: Remote data access method relies on recognition of predetermined calling line identities, by an interface unit 57. Upon recognition, the interface unit sends back data to the calling party from a data source such as a utility meter. Such meter readings are returned to a server 51. The server 51 may poll many different households by telephone. The interface unit 57 is arranged to intercept meter reading calls without the telephone ringing in the household. The system needs no changes to be made to the exchange in the telephone network.
Patent CA-2221591-A1 (CA)
Title: Tissue remodeling proteins
Inventor: KIRKPATRICK ROBERT B
IPC: C12Q1/6883
Filed: 1997-03-20
Abstract: Methods of detecting altered expression of tissue remodeling proteins and diagnosing tissue remodeling disorders are provided. Monoclonal antibodies against tissue remodeling proteins are also provided.
Patent CA-2223220-A1 (CA)
Title: Method and apparatus for blow molding hollow articles
Inventor: MCGLYNN DANIEL F
IPC: B29C49/62
Filed: 1997-11-28
Abstract: A method and apparatus for blow molding plastic articles which utilizes one or more fixed needles and one or more micro vents associated with a blow mold cavity.  Each needle has a first passage associated therewith through which vacuum is supplied to pull the molten plastic about the needle and a second passage therein through which air under pressure is introduced to tear the plastic and blow the article to the confines of the mold which has been closed about the plastic parison.  Micro vents facilitate exhausting air which is about the parison. Preferably the second passage for compressed air is provided by a central bore and the first passage for the vacuum is provided by an annular space about the fixed needle. In a modified form, the fixed needle comprises dual air passages. Provision is made for utilizing plural molds with controls for supplying air and vacuum.
Patent CA-2226551-A1 (CA)
Inventor: MANCINI FLAVIO
IPC: B22D17/02
Filed: 1996-05-24
Abstract: A sealing and guiding device for the injection piston of a hot chamber pump for corrosive alloys made up of a body in which a chamber and an injection cavity therebelow are formed, wherein the piston slides with a vertical reciprocating motion, includes a bush, having an outer diameter smaller than said chamber, interposed between centering members housed in the chamber and made coaxial with the chamber and with the piston by a pair of opposite surfaces of revolution formed on said centering members, the upper surface and the relevant centering member performing a pressure-tight sealing. The outer lateral surface of the bush is in communication with the injection cavity whereas the upper side of the bush is in communication with the crucible and immersed therein at a depth, measured from the lowest level reachable by the molten alloy, which is greater than the maximum travel of the piston. The inner surface of the bush is a surface of revolution with diameter just larger than the piston.
Patent CA-2226983-A1 (CA)
Title: Fuel additive compositions containing aromatic esters of polyalkylphenoxyalkanols and poly(oxyalkylene) amines
Inventor: MORRIS JACK E
IPC: C10L1/22
Filed: 1997-05-12
Abstract: A fuel additive composition comprising: (a) an aromatic ester compound of the formula: (see formula I) or a fuel soluble salt thereof, wherein R is hydroxy, nitro or -(CH2)x-NR5R6, wherein R5 and R6 are independently hydrogen or lower alkyl having 1 to 6 carbon atoms and x is 0 or 1;      R1 is hydrogen, hydroxy, nitro or -NR7R8, wherein R7 and R8 are independently hydrogen or lower alkyl having 1 to 6 carbon atoms;      R2 and R3 are independently hydrogen or lower alkyl having 1 to 6 carbon atoms; and R4 is a polyalkyl group having an average molecular weight in the range of about 450 to 5,000; and (b) a poly(oxyalkylene) amine having at least one basic nitrogen atom and a sufficient number of oxyalkylene units to render the poly(oxyalkylene) amine soluble in hydrocarbons boiling in the gasoline or diesel fuel range.      The fuel additive compositions of this invention are useful as fuel additives for the prevention and control of engine deposits.
Patent CA-2229788-A1 (CA)
Title: Process for the preparation of a disubstituted thiazole
Inventor: COOPER ARTHUR J
IPC: C07D277/28
Filed: 1997-05-19
Abstract: A process is disclosed for the preparation of N-((N-Methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl)-amino acid derivatives.
Patent CA-2230010-A1 (CA)
Inventor: ROUYER PASCAL GERARD
IPC: F02K3/06
Filed: 1998-02-20
Abstract: Un inverseur de poussée de turboréacteur à double flux comporte des portes pivotantes (7a, 7b) intégrées en jet direct dans la paroi extérieure du conduit (15) de flux de soufflante et constituant des obstacles de déviation de flux en procurant une inversion de poussée. Au moins deux vérins (23) de commande des déplacements de porte (7a, 7b) sont associés à un dispositif de synchronisation (19) constitué par un moteur électrique (20) et son système électronique de puissance (21) et un boitier de renvoi (22) relié respectivement par un lien de transmission (26) à chaque vérin (23). La sécurité de fonctionnement est ainsi assurée en cas de non-verrouillage d'une porte.
Patent CA-2233084-A1 (CA)
Title: Inhibiteurs de 5-.alpha.-reductase a 6-aza-steroides a substitution en position 16
Inventor: ASTER SUSAN D
IPC: C07J31/00
Filed: 1996-10-15
Abstract: L'invention concerne des composés représentés par la formule (I). Ces composés sont des inhibiteurs de 5.alpha.-reductase, utiles dans le traitement d'un certain nombre de manifestations de l'hyperandrogénie, à savoir par exemple: acné vulgaire, séborrhée, virilisme pilaire, calvitie hypocratique, carcinome prostatique, prostatite et adénome prostatique.
Patent CA-2233551-A1 (CA)
Title: Oil-free, water-soluble, hydroxyethyl cellulose, liquid, polymer dispersion
Inventor: HOFF MICHAEL H
IPC: C09K23/00
Filed: 1996-10-11
Abstract: The present invention is directed to an oil-free, water-soluble, liquid, polymer dispersion for use in thickening aqueous mediums, particularly completion and workover fluids used in the oil and gas drilling business. The dispersions of the present invention are comprised of hydroxyethyl cellulose and propylene glycol derivatives, preferably both propylene glycol polyether polyols and an aliphatic propylene glycol ether. Optionally these dispersions include water. Because of their low toxicity, these dispersions are particularly useful for drilling in offshore environments. These compositions rapidly disperse in and viscosify a variety of brines, including sea water and other light brines, with minimum shear and without fisheye formation.
Patent CA-2234103-A1 (CA)
Inventor: BASSAM DEAN ANTHONY
IPC: A01N53/08
Filed: 1996-10-10
Abstract: An insecticidal composition in the form of an aerosol water-in-oil emulsion is disclosed which comprises: (a) an amount of an aqueous suspension of microencapsulated insecticide to give an insecticide concentration in the composition of from 0.001 to 5% w/w; (b) one or more solvents in an amount of from 1 to 20% w/w; (c) one or more emulsifiers in an amount of from 0.2 to 10% w/w and selected from the group comprising mono-, di- and tri-sorbitan esters, polyoxyethylene sorbitan esters, mono- and poly-glycerol esters, ethoxylated nonionic emulsifiers, propoxylated nonionic emulsifiers and ethoxylated/propoxylated nonionic emulsifiers; (d) from 2 to 80% w/w of one or more propellants; (e) optionally from 0.001 to 5% w/w of one or more oil phase soluble insecticides; and (f) the balance being water.
Patent CA-2234618-A1 (CA)
Inventor: KLAASSEN WILLEM
IPC: B05B12/00
Filed: 1996-10-11
Abstract: The invention relates to an actuator grip (1) provided with a fixed grip part (3) and a trigger part (4) which is pivotally connected thereto and which is drivingly connectd to a movable member (6) of an apparatus for actuating by the hand-grip. The pivot connection (5) between the grip part (3) and the trigger part (4) is arranged on the side of the hand-grip remote from the member for actuating. An ergonomically sound and well controllable movement of the trigger part relative to the grip part is hereby obtained, whereby the apparatus connected to the hand-grip can be actuated accurately and with relatively little effort. The invention further relates to a caulking gun which is provided with a container for a medium for dispensing having an outlet aperture and a movable member for urging the medium for dispensing from the container through the outlet aperture, and an actuator grip as described above connected to the container and the movable member.
Patent CA-2234826-A1 (CA)
Title: Fluoxetine enteric pellets
Inventor: OREN PETER LLOYD
IPC: A61K9/36
Filed: 1998-04-14
Abstract: A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.
Patent CA-2236382-A1 (CA)
Title: Process for the production of 2h-1-benzopyrans
Inventor: FINNEY FRANCES
IPC: C07D311/58
Filed: 1997-08-13
Abstract: A process for the production of 2H-1-benzopyrans with general formula (I) where R1 is hydrogen, a (C1-C4) alkyl group, R2 is hydrogen, a (C1-C6) alkyl group and R3 is hydrogen, a (C1-C4) alkyl group, a (C1-C4) haloalkyl group, a (C2-C4) alkenyl group, a (C1-C4) alkoxycarbonyl group, a (C1-C4) alkoxymethyl group, a (C1-C4) alkanoyl group, a (C1-C4) alkoxy group, a (C1-C4) alkylsulphonyl group, halogen, amino alkylamino, dialkylamino nitril, nitro or hydroxy, is characterised in that in a first stage an aliphatic aldehyde with general formula (II) where R1 and R2 have the above-mentioned meaning, is converted with an aliphatic alcohol with the formula R4OH or HOR4OH, where R4 is a (C1-C4) alkyl group or a (C2-C4) alkyldiyl group, in the presence of a dehydrating compound with the formula HC(OR5)3, where R5 is a (C1-C4) alkyl group, and an aluminium oxide/silicium oxide catalyst into an aliphatic acetal with general formula (III) where R1 and R2 have the above-mentioned meaning and R4 as stated above is a (C1-C4) alkyl group or the two R4 together are a cyclical (C2-C4) alkyldiyl group, and this is then condensed in a second stage with a phenol with general formula (IV) where R3 has the above-mentioned meaning, in the presence of a base in an inert organic solvent, to the end product with general formula (I).
Patent CA-2241532-A1 (CA)
Title: Electromagnetic piston engine
Inventor: TAKARA MUNEAKI
IPC: F01B29/10
Filed: 1996-12-24
Abstract: The present invention relates to an electromagnetic piston engine capable of producing driving power by a reciprocal movement of a piston in a cylinder by electromagnetic force. The present invention has the objects to provide the electromagnetic piston engine which can do without a variety of resistance inherent in internal combustion piston engines, which reduces the weight corresponding to a rotary assembly portion to a smaller value even if a great output is produced, which can be readily employed together with power transmission mechanisms and so on for use with conventional internal combustion piston engines, and which has a high efficiency in enemy consumption. The electromagnetic piston engine is provided with the cylinder and the piston made each of a magnetic material as well as with as the cylinder electromagnet having the inner wall of the cylinder magnetizable to a one magnetic pole and with the piston magnetization unit for magnetizing a portion of the piston engageable with the cylinder to a single magnetic pole in a fixed manner.      The magnetization of the cylinder electromagnet generates magnetically attracting force between the cylinder and the piston to cause the piston to move in a one direction and thereafter magnetically repellent force to transfer the piston in the opposite direction. This series of the actions are repeated to provide a continual reciprocal movement of the piston.
Patent CA-2241750-A1 (CA)
Inventor: WIESEMANN AMADEUS
IPC: F16J15/10
Filed: 1997-12-15
Abstract: A fuel tank gasket (20) which before use consists essentially of a) 30-90 % by weight porous base material and b) 10-70 % by weight additive having the requirements that it is compatible with said porous material is taught. The porous base material of the gasket (20) is preferably expanded polytetrafluoroethylene and the additive is selected from the group consisting of perfluoropolyethers, polysiloxane, butadiene-acrylonitrile co-polymers, polyesters, polyethers as well as functionalised and fluorinated derivatives thereof. Preferably the additive is perfluoropolyether or a functionalised derivative thereof. A method for manufacture of the said fuel tank gasket comprising the following steps is furthermore described: a) a first step of manufacturing a porous base material (90), b) a second step of preparing an additive (70) in fluid phase, c) a third step of applying said additive (70) to said porous base material (90), d) a fourth step of drying the base fuel tank gasket (90). The fuel tank gasket (20) is used in transportation vehicles, such as an aircraft, for ensuring that fuel (7) does not leak out of the fuel tank (5) and water does not enter the fuel tank (5) and contaminate the fuel (7) therein.
Patent CA-2244113-A1 (CA)
Inventor: FROST GRANT
IPC: A61G1/007
Filed: 1998-08-24
Abstract: An anti chaffing device for the aid of rescuing trapped or injured patients. This device is shaped like a tapered snowboard, it is designed to accept a pull Strap at the front of board and has two counter sunk holes located centre line botttom third of board, it is made of a non-sparking material of sufficient thickness as to allow for two stainless bolts to flush mount skidder to the under side of the Wrap-Evac rescue harness patent application # 2,244,113
Patent CA-2245229-A1 (CA)
Inventor: BIAMONTE TONY DOMINIQUE
IPC: E21B43/12
Filed: 1998-08-17
Abstract: A  method  and  apparatus  for  reducing  water  in  gas producing well.  A first step involves inverting a submersible pump having an electric drive motor forming a pump assembly such that the electric drive motor is positioned above the submersible pump.  A second step involves lowering the pump assembly into a casing of a gas producing well until a selected production zone is reached.  A third step involves operating the submersible pump in an inverted orientation to inject excess water within the casing in the selected production zone into a disposal zone.  The apparatus relates to a pump assembly that includes a submersible pump in an inverted orientation and an electric drive motor above the submersible pump in an upright orientation.
Patent CA-2245278-A1 (CA)
Inventor: CARTY WALTER F
IPC: E04G1/34
Filed: 1998-09-03
Abstract: A work support or sawhorse having a pair of identical but reversed in arrangement brackets at each end of a horizontal rail for supporting legs and each end of the horizontal rail.      Each bracket comprises rotatable leg sections for holding the legs and hinges to enable each pair of legs to collapse against the underside of the horizontal rail. The peg sections are outwardly angled providing increased sawhorse stability. Tabs at the top of the leg sections insert into tab slots on the bottom of a hinged top plate for providing a stable sawhorse.
Patent CA-2248189-A1 (CA)
Title: System for determining analyte concentration
Inventor: CHRISTENSEN DOUGLAS A
IPC: G01N33/543
Filed: 1997-03-19
Abstract: The present invention relates to a system (80) for determining analyte concentration. The system (80) includes an optical detection system (92) that detects fluorescence from fluorescent binding assays in a biosensor (88). A processing system (96) may be used to determine analyte concentration from the fluorescence detected by the optical detection system (92). The optical detection system (92) may include photodetectors with or without in series lenses. Alternatively, a CCD camera (146) may be used.