baber/WOPTO huggingface dataset:
Patent CA-2150372-A1 (CA)
Title: Stable oral ci-981 formulation and process of preparing same
Inventor: MILLS NANCY L
IPC: A61K47/02
Filed: 1993-12-20
Abstract: An oral pharmaceutical composition is provided for treating hypercholesterolemia or hyperlipidemia containing an advantageous formulation for stabilizing the HMG-CoA coenzyme A inhibitor, CI-981 Hemi-Calcium, of formula (IA) with effective amounts of calcium carbonate. A method for preparing a CI-981 stabilizing composition is described.
Patent CA-2150464-A1 (CA)
Title: A pharmaceutical formulation for intraduodenal administration
Inventor: NYSTROEM CHRISTER
IPC: A61K47/38
Filed: 1993-11-29
Abstract: A pharmaceutical formulation for intraduodenal administration comprising at least one pharmacologically active agent, with limited solubility in water and is dispersed in an aqueous carrier. According to the invention, the active agent has a particle size not exceeding 20 µm, and the aqueous carrier has a viscosity of at least 300 mPas, measured at a moderate shear rate.
Patent CA-2154807-A1 (CA)
Title: Method of treating or preventing cardiac arrhythmia employing an n-substituted heterocyclic derivative
Inventor: SPINALE FRANCIS GUY
IPC: A61K45/06
Filed: 1995-07-27
Abstract: The invention relates to the use of an N-substituted heterocyclic derivative and its pharmaceutically acceptable salts for the treatment or prevention of cardiac arrhythmia. These derivatives have the structure I
Patent CA-2155342-A1 (CA)
Inventor: BLAKE ALAN DAVID
IPC: C11D11/04
Filed: 1994-01-28
Abstract: A process for producing high active alkyl sulphate solutions comprising the steps of adding and mixing an alkyl sulfuric acid having a chain length of C12-C18, with an organic amine to produce a neutralized product having substantially no water.
Patent CA-2162418-A1 (CA)
Inventor: VANDERHOOF RUSSELL A
IPC: H01R43/033
Filed: 1995-11-08
Abstract: A termination tool for terminating a plurality of wires to a modular connector, of the type consisting of a housing adapted to mate with a standard connector and contacts having insulation displacement portions disposed outwardly of the housing and further including a fixture for positioning the wires with respect to the insulation displacement portions.  The tool includes a pair of ribs projecting from a first planar contacting section and a second upwardly angled lever section.  The tool further includes a vertically oriented blade extending from the generally rectangular front end to untwist twisted wire pairs.
Patent CA-2162715-A1 (CA)
Title: 3-aminoazepine compound and pharmaceutical use thereof
Inventor: TOMOZANE HIDEO
IPC: C07K5/097
Filed: 1994-05-13
Abstract: 3-Aminoazepine compounds of the formula                 (I) wherein Ar is a phenyl or the like; R1 is a hydrogen, an alkyl or the like; R2 and R3 are the same or different and is a hydrogen, an alkyl, a group of the formula wherein R6 is heteroaryl or the like, a group of the formula wherein R7 is phenyl or the like, or the like; R4 is a hydrogen, an alkyl or the like; and X is an oxygen atom or a sulfur atom, and R4 and X are bonded to each other to form a group of the formula : -C(R10)=N-N= where R10 is hydrogen, alkyl or the like, optically active compounds thereof and pharmaceutically acceptable salts thereof.  The compounds of the present invention have CCK antagonistic action and gastrin antagonistic action, and are useful as a therapeutic agent for central nervous diseases such as anxiety and depression, and an agent for the prophylaxis and treatment of pancreatic disorders and gastrointestinal ulcers.
Patent CA-2164508-A1 (CA)
Inventor: CROSS ELISA M
IPC: C08G18/38
Filed: 1994-04-21
Abstract: L'invention concerne un monomère azoïque optiquement actif non linéaire du second ordre contenant un groupe benzimidazole. De tels monomères peuvent être incorporés aussi bien dans des polymères linéaires que dans des polymères réticulés, qui sont utiles dans les dispositifs électro-optiques.
Patent CA-2166100-A1 (CA)
Title: Sigma receptor ligands and the use thereof
Inventor: GLENNON RICHARD A
IPC: C07D211/52
Filed: 1994-06-23
Abstract: The invention relates to methods for the treatment of central nervous system disorders, neurological disorders, gastrointestinal disorders, drug abuse, angina, migraine, hypertension and depression by administering a pharmaceutical composition comprising an effective amount of certain sigma receptor ligands to a patient in need of such treatment. The invention further relates to novel sigma receptor ligands having high binding to the sigma receptor and pharmaceutical compositions thereof.
Patent CA-2167940-A1 (CA)
Inventor: ASHLEY JAMES PATRICK
IPC: H03H17/00
Filed: 1995-05-26
Abstract: A method and apparatus are provided for echo canceling which includes double-talk immunity. The echo canceller (15) according to the present invention includes a double-talk detector (17) which uses an adaptive double-talk detection threshold (214) and an accurate estimation of reference energy (106) to detect double-talk. The echo canceller further provides for correcting partial echo canceller adaptive filter vector divergence occurring prior to double-talk detection by maintaining and switching to an auxiliary echo canceller filter with known "good" filter coefficients (58, 60, 62).
Patent CA-2169938-A1 (CA)
Title: Grb3-3 gene; variants and uses thereof
Inventor: SCHWEIGHOFFER FABIEN
IPC: A61K48/00
Filed: 1994-05-09
Abstract: Novel gene known as Grb3-3, variants thereof and use especially in anti-cancer gene therapy.
Patent CA-2170215-A1 (CA)
Inventor: CHRISTENSON RONALD E
IPC: B65F3/04
Filed: 1996-02-23
Abstract: The disclosure describes container handlers having a swivel mount pivotally attached to a handler base that pivots between a lowered and a raised position.  A handle engaging flange   secured to the swivel mount engages a container of interest as the swivel mount is raised.  In one  embodiment,  a  corresponding  rim  gripping  flange attached to the base holds the container rim between the flanges in the raised position and active suction cups carried by the swivel mount also engage and hold the container  during  unloading  operations.  In  another embodiment, a second handle engaging flange is pivotally attached to  the  swivel  mount  for  pivoting  between  a retracted and a handle engaging position.   The second flange engages a second spaced parallel handle before the container  is tilted for unloading.   The base of each embodiment may be connected to any lifting device, such as an  articulated  multiple-member  support arm  or  boom connected to a refuse truck.
Patent CA-2174964-A1 (CA)
Title: Method and device for measuring the properties of granular earth materials
Inventor: PAAKKINEN ILMARI
IPC: G01N3/08
Filed: 1994-10-25
Abstract: The invention relates to a method and device for measuring the properties of earth materials subjected to a load, the device comprising a cylinder (10) for a material sample enclosed by a cover and bottom plate (6a, 7a), means for compressing the sample, means for making the central axes of the cover and bottom plate deviate parallel to each other by an angle in relation to the central axis of the cylinder and in the same plane with the central axis of the cylinder, and means for making the central axes of the cover and bottom plate revolve about the central axis of the cylinder (10) with said angular deviation so as to deform the sample. In order to make the measuring more effective the material is measured by means of a device which is provided with means (13 to 16) for measuring the force resisting the deformation of the sample in the direction of the radius of the sample, and for measuring the force resisting the deformation of the sample in the direction of rotation of the angular deviation.
Patent CA-2175634-A1 (CA)
Title: Injection molding valve member with head and neck portions
Inventor: BAUER KLAUS
IPC: B29C45/28
Filed: 1996-05-02
Abstract: An injection molding valve member having a smaller neck portion leading to a short head portion. This facilitates the backflow of melt around the head portion as the valve member is driven forwardly to the closed position. In one embodiment, the neck portion is formed by a number of flutes spaced around the valve member having lands between them.
Patent CA-2176396-A1 (CA)
Title: Magnetic pole shoe dc motor assembly
Inventor: MASON ELMER B
IPC: H02K23/02
Filed: 1994-10-11
Abstract: A direct current motor (10) having an armature (28) axially supported between magnetic pole plates (15-16, 17-18, 19-20) having opposing pairs of pole shoes (50-52; 60-62) extending in interdigital parallel opposition with respect to the periphery of the armature between the pole plates adjacent the armature, is energized by direct current through a pair of coils (24, 25) interposed between and connected with the magnetic pole plates.  The respective ends of selected pole shoes are connected with pole plates of like polarity magnetic flux and similarly the remaining of pole shoes are connected at their respective ends with pole plates of opposite polarity magnetic flux density. Wiring (69) and electrical current controls (68) connect a DC source (B) to the coils and armature for providing a maximum torque and drive shaft speed with a minimum of ampere drain from the DC source.
Patent CA-2176439-A1 (CA)
Inventor: TURFAN FARUK M
IPC: B65B11/02
Filed: 1996-05-13
Abstract: Apparatus for wrapping articles in film material includes a stationary frame supporting a vertically reciprocable frame which in turn supports a rotatable ring member carrying a film carriage assembly by which film is wrapped around a load during rotation of the ring member. The ring member is a cast composite ring of a thermosetting, fiberglass reinforced polyester and comprises a flange by which the ring member is supported for rotation and a body portion on which the film carriage and slip ring members are mounted.
Patent CA-2176725-A1 (CA)
Title: Safety cab arrangement for an underground mobile machine
Inventor: KORTELAINEN ANTTI
IPC: B60R21/11
Filed: 1994-11-16
Abstract: The invention relates to a safety cab arrangement for an underground mobile machine intended, for example, For mining. A safety cab (2) secured to the frame of the machine (1) is equipped with L shaped outside safety bars (3) which receive forces and which are secured to the safety cab (2) and to the machine (1). The safety cab (2) transmits lateral and longitudinal forces to the safety bars and withstands vertical forces independently,
Patent CA-2177599-A1 (CA)
Inventor: PREVOST ISABELLE
IPC: C10L10/14
Filed: 1995-10-03
Abstract: On liquéfie un gaz naturel sous pression comprenant au moins un cycle de réfrigération à l'aide d'un mélange de fluides réfrigérants en procédant au moins aux étapes suivantes: a) on condense au moins en partie ledit mélange réfrigérant en le comprimant (K1) et en le refroidissant (C1), par exemple, à l'aide d'un fluide externe de refroidissement, pour obtenir au moins une fraction vapeur (5) et une fraction liquide (6), b) on détend séparement (T1, V1) au moins en partie chacune des fractions vapeur et liquide pour obtenir un fluide léger M1 composé on majorité d'une phase vapeur et un fluide lourd M2 composé en majorité d'une phase liquide, c) on mélange au moins en partie les fluides M1 et M2 pour obtenir un mélange (10) à basse température, et d) on liquéfie et on sous-refroidit le gaz naturel sous pression (1) par échange thermique avec le mélange à basse température obtenu au cours de l'étape c).
Patent CA-2178902-A1 (CA)
Title: Controlled release of pharmaceutically active substances for immunotherapy
Inventor: PARDOLL DREW
IPC: A61K39/39
Filed: 1994-12-13
Abstract: A method of stimulating a systemic immune response to a tumor cell or antigen associated with a pathogen by administering a mixture of a controlled release vehicle containing an immunopotentiating agent and antigen is described.
Patent CA-2179922-A1 (CA)
Title: Method and apparatus for producing parts by layered subtractive machine tool techniques
Inventor: RICHARDSON KENDRICK EUGENE
IPC: G06F19/00
Filed: 1996-06-25
Abstract: A method of forming a three-dimensional object (38) is provided using a combination of molding and machining. In its most basic form, the method of the present invention is achieved by depositing a first layer of mold material (40) onto a support surface (20), machining a first cavity (42) into the first layer of mold material, depositing a first layer of construction material (52) onto the first layer of mold material such that an overlapping portion (52a) of the first layer of construction material fills the first cavity to form a first three-dimensional section of the object and such that a superposing portion (52b) of the layer of construction material covers the first layer of mold material, and machining the superposing portion (52b) to form a second three-dimensional section of the object. A larger object may be produced by repeating such steps in like sequence to form additional three-dimensional sections. In the apparatus of the present invention, control of deposition of materials through dispensers (14, 16) and subsequent machining operations by sculpting means (12) is achieved automatically by a director (24) controlled by a computer system (30) comprised of a microprocessor (34) and a CAD/CAM system (36).
Patent CA-2184148-A1 (CA)
Inventor: NOONE ROBERT P
IPC: G09F21/04
Filed: 1996-08-26
Abstract: A  kit  to  outfit  a  stock  motor  vehicle  with decorative  features  related  to  a  sports  team. Embodiments of the kit include one to accommodate any motor vehicle make or model, a second tailored to a specific manufacturer's make and model of vehicle, a third to provide an after-market customizing kit. Each of the kit items are coordinated to display the colors,   identifying   features,   mascots,   playing implements, or other indicia related to a sports team or sports figure.  Items include a wide adhesive tape decorated with a plurality of stripes for application to the exterior of a motor vehicle; a decorative hood ornament;  wheel  cover  decals;  stickers  and  signs displaying a team name or logo, for both permanent and temporary application; a string of decorative mini-lights;  sunvisor  decals;  decorative  floor  mats; decorative seat covers; a decorative gear shift lever knob; and a decorative clock.  The sports indicia are applied  to  magnetic  flexible  sheet  materials  for temporary use,  or to plastic  sheet material  with permanent adhesive backings for permanent application. Additional items include an ice chest form-fitted to the interior of the tailgate storage area of a motor vehicle and additional direct current electrical plug outlets  for  retrofit  installation  into  a  motor vehicle.
Patent CA-2189221-A1 (CA)
Inventor: KLEEMANN HEINZ-WERNER
IPC: C07C381/10
Filed: 1996-10-30
Abstract: Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Sulfonimidamides of the formula I (see formula I) in which at least one of the three substituents R(1), R(2) and R(3) is a benzoylguanidine, and in which the other substituents have the meanings indicated in the claims, are outstandingly suitable as medicaments having action on the cardiovascular system; that is as antiarrhythmic pharmaceuticals having a cardioprotective component as well as for treating ischemically induced damage; also in operative interventions, such as organ transplantation.
Patent CA-2189545-A1 (CA)
Title: Safety valve
Inventor: SMART LARRY WESLEY
IPC: F16K17/08
Filed: 1994-11-30
Abstract: A safety pressure relief valve includes a seat bushing (41) defining an inlet flow passage, a valve seat (45) on the inward end of the seat bushing (41), a valve disc (40) having a seat (43) thereon movably mounted in the valve body for opening and closing the valve, and a spring (21) coupled with the disc for biasing the disc (40) toward a closed position.  The disc (40) includes a convex end portion (44) to reduce turbulence during flow into the valve for improved seating of the disc and an external annular recess defining an annular lip (50) on the disc (40) including a seat having a frustoconical seat surface (45), the lip (50) being flexible to improve the disc seat contact with the seat to increase the seat tightness of the valve.
Patent CA-2191907-A1 (CA)
Inventor: APOSTOLOPOULOS JOHN G
IPC: H04N7/30
Filed: 1996-12-03
Abstract: The invention is an image transmitting method and system including receiving encoded images, decoding those images and post-processing the decoded images.  The post-processing reduces visual artifacts, such as blocking artifacts and mosquito noise, through separate detection, mapping and smoothing operations while avoiding many of the complexities associated with existing techniques. In detecting blocking artifacts, the inventive method employs DCT-domain detection rather than edge detection in the pixel domain. Also, the interior of a detected block is updated based on the surrounding blocks without disturbing the surrounding blocks. In reducing mosquito noise, the inventive method smoothes the non-edge pixels within blocks containing edge pixels rather than smoothing the edge pixels. Also, distortion-induced false edge pixels are distinguished from true edge pixels and heavily smoothed. The post-processing method and system is generally applicable to Block DCT based compression systems, either intrinsically or extrinsically.
Patent CA-2192100-A1 (CA)
Title: Detection of a Low Level Marshalling Sequence
Inventor: WELTON PAUL DOUGLAS
IPC: H04J14/08
Filed: 1995-06-21
Abstract: In a TDMA communications system comprising a base station and a number of outstations, a marshalling signal enables a newly connected outstation to determine the timing of its transmission bursts. A detector circuit for recovering the marshalling signal incorporates comparators (21, 41) whose thresholds are adjusted to the high and low levels of the normal data signal.  The marshalling signal is recovered from one or other of the comparators (21, 41) according to whether a high or low normal data signal is received, this condition being determined by a third comparator (31) whose threshold is adjusted midway between the high and low level. This allows the marshalling signal to be recovered continuously without interrupting normal data transmission from the outstation.
Patent CA-2192342-A1 (CA)
Title: A method for large scale plasmid purification
Inventor: LEE ANN L
IPC: A61K48/00
Filed: 1995-07-11
Abstract: A process is disclosed for the large scale isolation and purification of plasmid DNA from large scale microbial fermentations. All three forms of plasmid DNA; supercoil (form I), nicked or relaxed circle (form II), and linearized (form III), are individually isolatable using the disclosed process. Highly purified DNA suitable for inclusion in a pharmaceutical composition is provided by the disclosed process.
Patent CA-2193031-A1 (CA)
Title: Dispersion of post-curable coating compounds
Inventor: KOENIG EBERHARD
IPC: C14C11/00
Filed: 1996-12-16
Abstract: The invention relates to a method for coating textiles and/or leather with an aqueous dispersion comprising (A) a mixture of (i) a urethane-containing blocked NCO prepolymer having a number average molecular weight of 2000 to 10,000, a content of blocked isocyanate groups (calculated as NCO) of 0.5 to 5 wt.%, an ethoxy group content of 2 to 50 wt.%, an ionic group content of 5 to 30 meq per 100g of the prepolymer, and (ii) a polyamine having (cyclo)aliphatically bonded primary and/or secondary amino groups, wherein the equivalent ratio of blocked NCO groups of component (i) to amino groups of component (ii) is 1:0.9 to 1:1.2, and (B) an aqueous phase.
Patent CA-2196200-A1 (CA)
Title: Novel compounds
Inventor: BROWNE MICHAEL JOSEPH
IPC: A61K39/395
Filed: 1995-07-28
Abstract: A soluble protein having IL4 and/or IL13 antagonist or partial antagonist activity comprises an IL4 mutant or variant fused to at least one human immunoglobulin constant domain or fragment thereof.
Patent CA-2199836-A1 (CA)
Title: Integrating accelerometer capable of sensing off-axis inputs
Inventor: MOSS JAMES R
IPC: H01H35/14
Filed: 1995-09-25
Abstract: Compounds of formula (I) wherein R1 and R2 are each independently F, Cl, Br, CH3, CH2CH3 or CF3; R3 is H, CH3 or CH2CH3; and X is a 5-membered heterocyclic group containing up to four nitrogen atoms, attached via a nitrogen atom, the said group being optionally benzofused and/or substituted by C1-C6 alkyl or (CH2)nNR4R5, wherein n is an integer from 1 to 5 and R4 and R5 are each independently H, C1-C6 alkyl, C3-C6 cycloalkyl or C1-C4 alkyl substituted by phenyl or pyridyl, or R4 and R5 are linked to form, together with the nitrogen atom to which they are attached, a pyrrolidine, piperidine, piperazine, N-(C1-C4 alkyl) piperazine, morpholine or azepine group; and their pharmaceutically acceptable salts, are NMDA antagonists of utility in the treatment of acute neurodegenerative disorders, e.g. arising from stroke or traumatic head injury and in chronic neurological disorders, e.g. senile dementia and Alzheimer's disease.
Patent CA-2200907-A1 (CA)
Title: Visible neutral bar
Inventor: RHODES JOHN MICHAEL
IPC: H02B1/056
Filed: 1997-03-25
Abstract: An electric load center having a neutral bar having an elongated body portion with a trapezoidal shaped cross-sectional area with outwardly sloping downwardly extending side walls having apertures for insertion of electrical wires and a base portion having mounting rails being adapted to form a generally T-shaped slot, and a basepan having a surface with an upwardly extending flexible snap hook for engaging the mounting rail of the T-shaped slot.
Patent CA-2202147-A1 (CA)
Title: Compaction roller assembly and grader
Inventor: ROTH SCOTT R
IPC: E01C19/26
Filed: 1995-10-18
Abstract: A compaction roller assembly (10) includes a lobed non-circular impact roller (12) operably mounted on a draw frame (14) and a grader (16) operably mounted behind the impact roller (12) to level the corrugated ground surface produced by the impact roller. The grader (16) includes a pair of diverging frame members (22) with a pair of blades (54) mounted thereon and depending therefrom with the lower edges of the blades lying within a generally horizontal plane. A  plurality of teeth (60) may be mounted to the frame members (22) to scarify the soil, each tooth (60) being removably connected to the frame members to permit ease of conversion between a grader blade and a scarifier. Each tooth (60) is a generally flat plate, the plates oriented parallel to one another and parallel to the line of travel of the grader (16). Each tooth plate forward edge (68) includes a concave arc-shaped lower portion extending from the lower end of the tooth to a point proximal the lower edge of the blade. Removable support skids (86) are provided to the frame member for supporting the grader in fine particulate soil.
Patent CA-2204703-A1 (CA)
Title: Structured packing element with bi-directional surface texture and a mass and heat transfer process using such packing element
Inventor: PILLARELLA MARK ROBERT
IPC: B01J19/30
Filed: 1997-05-07
Abstract: The present invention provides for a structured packing element, the element being corrugated with corrugations which form alternating peaks and troughs across the element, the corrugations having a longitudinal axis, the element having at least one band of first fluting at an angle between 0° and 180° to the longitudinal axis of the corrugations and at least one band of second fluting at an angle between 0° and 180° to the longitudinal axis of the corrugations, the first fluting being at an angle greater than zero to the second fluting. The element preferably has a plurality of holes through the element. The foregoing structured packing is suited for use in processes requiring a contact device foraccomplishing mass and/or heat transfer. The foregoing structured packing is particularly suited for a cryogenic air separation process comprising contacting vapor and liquid countercurrently in at least one distillation column containing at least one mass transfer zone wherein liquid-vapor contact is established by at least one structured packing element.