baber/WOPTO huggingface dataset:
Patent WO-2020097216-A1 (WO)
Title: Macrostructure topology generation with physical simulation for computer aided design and manufacturing
Inventor: BANDARA KONARA MUDIYANSELAGE KOSALA
IPC: G06F113/10
Filed: 2019-11-06
Abstract: Methods, systems, and apparatus, including medium-encoded computer program products, for computer aided design of physical structures using generative design processes, where three dimensional (3D) models of the physical structures can be produced to include lattices, hollows, holes, and combinations thereof, include: obtaining design criteria for an object; and iteratively modifying 3D topology and shape(s) for the object using generative design process(es) that employ a macrostructure representation, e.g., using level-set method(s), in combination with physical simulation(s) that place void(s) in solid region(s) or solid(s) in void region(s) of the generative model of the object; and providing a 3D model of the generative design for the object for use in manufacturing a physical structure corresponding to the object using one or more computer-controlled manufacturing systems. The providing can include generating instructions for manufacturing machine(s), which can employ various manufacturing systems and techniques, including additive, subtractive and casting manufacturing methods.
Patent WO-2020102068-A1 (WO)
Inventor: HAND JOSHUA
IPC: F16D28/00
Filed: 2019-11-11
Abstract: Overrunning coupling and control assembly and control system for use therein are provided. The system includes a control member mounted for controlled shifting movement between the coupling faces of first and second coupling members. An actuator arm includes an output member and a one-way locking member which is pivotally connected to output member which, in turn, is coupled to the control member. The locking member moves between a disengaged position in which the control member is permitted to shift or rotate relative to the second coupling member and an engaged position with a locking member-engaging portion of the second coupling member to lock the control member and the second coupling member together to prevent the control member from inadvertently shifting in a first direction relative to the second coupling member in the absence of an actuator command signal received by a bi-directional actuator assembly of the system.
Patent WO-2020102560-A1 (WO)
Inventor: LUDWIG JOSEPH
IPC: A61P29/00
Filed: 2019-11-14
Abstract: Provided herein are methods for treating small round cell tumor(s) by administering anti-androgen receptor therapy to a subject. The anti-androgen receptor therapy may comprise an AR antisense oligonucleotide and may be administered in combination with an additional anti-cancer agent.
Patent WO-2020123206-A1 (WO)
Inventor: LESLIE DAVID
IPC: E04D13/04
Filed: 2019-12-03
Abstract: La présente invention concerne un appareil de vidange de puisard comprenant une cuve de vidange, une rampe reliée à la cuve de vidange comprenant un plan incliné conçu pour dévier l'eau de drainage vers la cuve de vidange, et une bride de fixation reliée à la rampe et conçue pour coupler l'appareil de drain de puisard à un platelage de toit, la rampe étant conçue pour être positionnée au-dessus du platelage de toit et contenir une isolation de puisard sous la rampe et au-dessus du platelage de toit.
Patent WO-2021029905-A1 (WO)
Inventor: MEI RYAN
IPC: H03K3/356
Filed: 2020-01-02
Abstract: An improved level shifter for use in integrated circuits is disclosed. The level shifter is able to achieve a switching time below 1 ns while still using the core power supply voltages, VDDL and VDDH, used in the prior art. The improved level shifter comprises a coupling stage and a level-switching stage.
Patent WO-2020154175-A1 (WO)
Inventor: RICE JUSTIN
IPC: A61M1/00
Filed: 2020-01-16
Abstract: L'invention concerne un pansement pour traiter un site tissulaire avec une pression négative, des procédés de fabrication du pansement, et des procédés d'utilisation du pansement. Le pansement comprend un collecteur de parage ayant une pluralité de premières régions ayant une première densité, et une pluralité de secondes régions ayant une seconde densité inférieure à la première densité. Le pansement peut comprendre un élément de recouvrement configuré pour être disposé sur le collecteur de parage. L'élément de recouvrement comprend un périmètre s'étendant au-delà du collecteur de parage.
Patent WO-2020154679-A1 (WO)
Inventor: LAEZZA FERNANDA
IPC: C07K5/10
Filed: 2020-01-24
Abstract: The present invention relates to novel small molecules Formula I and pharmaceutically acceptable salts thereof as well as the preparation and the use thereof to inhibit FGFl3-lb.
Patent WO-2020180538-A1 (WO)
Title: Method and system for analyzing electronic communications and customer information to recognize and mitigate message-based attacks
Inventor: KESSLER JOSEPH
IPC: G06Q10/10
Filed: 2020-02-25
Abstract: A method includes receiving a message, enqueueing the message, dequeueing the message by a fraud detection service, analyzing the message using a trained machine learning model, analyzing an isolated domain name, storing the message, and causing a mitigation action. A computing system includes a transceiver, a processor, a memory storing instructions that when executed by the processor cause the system to receive a message, enqueue the message, dequeue the message, analyze the message using a machine learning model, analyze an isolated domain name, store the message, and cause a mitigation action. A non- transitory computer readable medium contains instructions that when executed, cause a computer to receive a message, enqueue the message, dequeue the message by a fraud detection service, analyze the message using a machine learning model, analyze an isolated domain name, store the message, and cause a mitigation action.
Patent WO-2020176847-A1 (WO)
Inventor: CLARKE DAVID
IPC: A61B5/11
Filed: 2020-02-28
Abstract: A wearable haptic device and methods of operating a wearable haptic device to provide haptic stimulation to a user are described. The haptic device comprises a band configured to be worn around a portion of a user's body, circuitry coupled to a flexible substrate, wherein the flexible substrate is coupled to the band, and a plurality of dielectric elastomer actuators electrically connected to the circuitry, each of the plurality of dielectric elastomer actuators including a rolled elastomer structure having electrode elements embedded therein, wherein the plurality of dielectric actuators are coupled to the circuitry to provide haptic stimulation to the portion of the user's body when the wearable haptic device is worn on the portion of the user's body and is actuated.
Patent WO-2020181127-A1 (WO)
Inventor: THONGSUKMAK ATSAWIN
IPC: A61K9/00
Filed: 2020-03-05
Abstract: The present disclosure provides programmable osmotic-controlled oral compositions providing delayed extended release of a therapeutically acceptable amount of methylphenidate hydrochloride. The programmable osmotic-controlled compositions of the disclosure provide a lag time that is independent of the presence or absence of food, type of food, pH, gastric emptying, and volume of gastric fluid. The compositions of the disclosure can be programmed to provide a desired and precise lag time, and release drug, after the lag time, at a rhythm that matches the circadian rhythm of an individual being treated to optimize therapeutic outcome and minimize side effects.
Patent WO-2020263359-A1 (WO)
Title: Computationally efficient mixed precision floating point waveform generation
Inventor: BARILLAS ENDER
IPC: G06F1/03
Filed: 2020-03-09
Abstract: Computationally efficient mixed precision floating point waveform generation takes advantage of the high-speed generation of waveforms with single-precision floating point numbers while reducing the generally unacceptable loss of precision of pure single-precision floating point to generate any waveform that repeats in 2π. This approaches computes a reference phase in double precision as the modulus of the phase with 2π and then computes offsets to that value in single precision. The double precision reference phase is recomputed as needed depending on how quickly the phase grows and how large a machine epsilon is desired.
Patent WO-2020197929-A1 (WO)
Title: Dual fidelity connectivity on-board a vehicle
Inventor: AYOTTE LOREN
IPC: H04L45/125
Filed: 2020-03-19
Abstract: Systems and methods for providing dual fidelity communications to devices on board a vehicle. The systems and method integrate light fidelity (LiFi) communications with traditional vehicle radio frequency (RF) communications and/or wired communications systems. The systems and method may include detecting data packets addressed to devices on-board the vehicle and determining a metric associated with a data packet and or data stream associated with the data packet. Based on the determined metric, the data packet is routed over the LiFi communication system or the traditional RF or wired communication system.
Patent WO-2020205647-A1 (WO)
Inventor: MILLER KYLE
IPC: G06F16/74
Filed: 2020-03-27
Abstract: Systems and associated methods are described for providing content recommendations. The system accesses a plurality of recommendation algorithms and assigns a plurality of weight values to each prediction algorithm. Then, the system generates a set of candidate weight combinations, such that each candidate combination includes a weight value assigned to each prediction algorithm. Then requests for content items are received over a predetermined period of time. For each combination, the system generates a set of recommended content items and an evaluation metric that is based on matches with requests. Afterwards, the system replaces a candidate combination that resulted in a generation of a lowest evaluation metric. The aforementioned steps are repeated until the evaluation metrics stop improving. Then display identifiers are displayed for a set of recommended content items generated for a candidate combination with the highest evaluation metric.
Patent WO-2020210063-A1 (WO)
Title: Boring bit component with hard face wear resistance material with subsequent heat treatment
Inventor: JOHNSON KEITH A
IPC: B23B39/02
Filed: 2020-03-28
Abstract: A boring bit or other component for horizontal directional drilling is provided which includes a hard faced layer that is preferably made by a laser cladding bead. A subsequent or post heat treatment is applied to modify the heat affected zone (HAZ) to eliminate or reduce the hard brittle regions and/or softer regions in the base iron or steel material of the HAZ. Further, the hard faced layer may be applied in combination with carbide insert teeth that are embedded within the steel base of the boring bit body, such as by press fitting.
Patent WO-2020210219-A1 (WO)
Inventor: BRUGGER JAMES
IPC: F16L37/12
Filed: 2020-04-07
Abstract: Fluid couplings prevent or discourage misconnection of fluid lines. In embodiments, a coupling device includes multiple male and female connectors that are joined to a common line. The coupling device is mated to a matching coupling device only when all the multiple male and female connectors are properly joined. If any of the connectors is not properly mated to a corresponding one, the coupling will leak, since the connectors on each side are joined to a furcating channel. In embodiments, the coupling devices are made unique by providing an arrangement of the connectors, number of connectors, shape of connectors or arrangement of interfering connector parts that ensure that any attempt to improperly couple two fluid lines will result in the incomplete mating and thereby cause leakage of the fluid, failure of the coupling to engage, or otherwise cause the attempt to connect to fail.
Patent WO-2020210372-A1 (WO)
Title: Compositions and methods for nucleotide modification-based depletion
Inventor: GOURGUECHON STEPHANE B
IPC: C12N9/14
Filed: 2020-04-08
Abstract: Provided herein are compositions and methods for enriching a sample for nucleic acids of interest relative to nucleic acids targeted for depletion, comprising using differences in nucleotide modification between the nucleic acids of interest and the nucleic acids targeted for depletion.
Patent WO-2020227484-A1 (WO)
Inventor: DYCKMAN ALARIC J
IPC: C07D519/00
Filed: 2020-05-07
Abstract: Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein G, A, R 1 , and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
Patent WO-2020242758-A1 (WO)
Inventor: MATHEJA TIMO
IPC: H04J1/12
Filed: 2020-05-12
Abstract: Gain mismatch and related problems can be solved by a system and method that applies an automatic microphone signal gain equalization without any direct absolute reference or calibration phase. The system and method performs the steps of receiving, by a computing device, a speech signal from a speaking person via a plurality of microphones, determining a speech signal component in the time- frequency domain for each microphone of the plurality of microphones, calculating an instantaneous cross-talk coupling matrix based on the speech signal components across the microphones, estimating gain factors based on calculated cross-talk couplings and a given expected cross-talk attenuation, limiting the gain factors to appropriate maximum and minimum values, and applying the gain factors to the speech signal used in the control path to control further speech enhancement algorithms or used in the signal path for direct influence on the speech enhanced audio output signal.
Patent WO-2020236501-A1 (WO)
Inventor: COON ERIN
IPC: C03C3/097
Filed: 2020-05-14
Abstract: A silicate-based glass composition includes: 40-60 wt.% SiO 2 , 0-10 wt.% B 2 O 3 , 0.01-10 wt.% P 2 O 5 , 0-10 wt.% Al 2 O 3 , 0-5 wt.% Li 2 O, 10-30 wt.% Na 2 O, 0.01-15 wt.% K 2 O, 0.01-5 wt.% MgO, 15-30 wt.% CaO, 15-35 wt.% MO, and 15-30 wt.% R 2 O, such that MO is the sum of MgO, CaO, SrO, BeO, and BaO, and R 2 O is the sum of Na 2 O, K 2 O, Li 2 O, Rb 2 O, and Cs 2 O.
Patent WO-2020251728-A1 (WO)
Title: Knee walker with four-wheel steering
Inventor: JERNIGAN HARRY W
IPC: A61H3/00
Filed: 2020-05-18
Abstract: A knee walker with four-wheel steering. The knee walker includes a frame, at least one front axle assembly, at least one rear axle assembly, a kneeling pad assembly, and a steering system. The steering system is configured to turn the rear axle assembly in the opposite direction from the front axle assembly. The opposing angles of the front and rear wheels enable the knee walker to perform tighter turns by eliminating rear wheel drag.
Patent WO-2020257612-A1 (WO)
Title: Assemblage de séquences d'acide nucléique basé sur des code-barres
Inventor: NUGENT REBECCA
IPC: C40B40/08
Filed: 2020-06-19
Abstract: La présente invention concerne des méthodes, des systèmes et des compositions pour un assemblage d'acide nucléique efficace. L'assemblage d'acide nucléique peut comprendre un assemblage de variants comprenant une homologie appariée.
Patent WO-2021262163-A1 (WO)
Inventor: BARCELO STEVEN
IPC: G01N21/64
Filed: 2020-06-24
Abstract: In example implementations, an apparatus is provided. The apparatus includes a plasmonic sensor that is functionalized to immobilize a target molecule, a first light source, a second light source, and a detection device. The first light source is to provide heat to perform a polymerase chain reaction to create copies of the target molecule on the plasmonic sensor. The second light source is to induce luminescence on the plasmonic sensor. The detection device is to generate a detection signal of the target molecule based on an intensity of the luminescence that is scattered by the plasmonic sensor.
Patent WO-2021003086-A1 (WO)
Title: Tasimelteon use in treating sleep aberrations
Inventor: POLYMEROPOULOS MIHAEL
IPC: A61P43/00
Filed: 2020-06-29
Abstract: The invention relates generally to circadian rhythm disorders and, more particularly, to the treatment or prevention of circadian rhythm disorders based on an individual's HCN1 genotype. One aspect of the invention provides a method of treating an individual for delayed sleep time comprising: determining or having determined from a biological sample of the individual that the individual has a GG genotype at the rs12188518 single nucleotide polymorphism (SNP) locus; and administering to the individual once daily before a target bedtime a dose of tasimelteon effective to advance the sleep time of the individual. Other genotypes related with circadian rhythm disorders are CC at rs11248864 and AA at rs72762058.
Patent WO-2021016284-A1 (WO)
Title: Mud shearing unit, system, and method
Inventor: GROENNVOLD BJOERN
IPC: E21B21/06
Filed: 2020-07-22
Abstract: A mud shearing unit including an inlet, an outlet, a diffusion chamber connected to the outlet, a shearing nozzle connected between the inlet and the diffusion chamber, and a static fan interrupting mud flowing from the shearing nozzle to the outlet. A mud shearing system includes the mud shearing unit, a high-pressure (HP) mud pump, and a tank. The HP mud pump pumps mud to the mud shearing unit inlet at a first pressure. The tank is connected to the mud shearing unit outlet, thereby receiving mud from the mud shearing unit at a second pressure that is less than the first pressure. The mud shearing unit may provide a predetermined pressure drop range between the first and second pressures. The tank may be multiple tanks, and the system may further include a low-pressure manifold connected between the mud shearing unit outlet and each tank.
Patent WO-2021086463-A1 (WO)
Title: Methods and apparatus for processing a substrate
Inventor: PENG QI JIE
IPC: H01L21/687
Filed: 2020-07-28
Abstract: Methods and apparatus for processing a substrate are provided herein. For example, a system for processing a substrate includes a process chamber comprising a first processing volume and a second processing volume; a first heating device configured to heat a substrate to a first temperature; a carrier configured to support the substrate while the substrate is being heated using the first heating device to the first temperature and transfer the substrate to and from each of the first processing volume and the second processing volume; a second heating device configured to maintain the substrate at or near the first temperature; and a chuck configured to receive the substrate from the carrier, and comprising an outer zone and an inner zone having independent variable pressure control to apply a chucking force at the outer zone that is different from a chucking force provided at the inner zone.
Patent WO-2021021877-A1 (WO)
Title: Composés agonistes de gipr
Inventor: ALSINA-FERNANDEZ JORGE
IPC: A61K38/16
Filed: 2020-07-29
Abstract: La présente invention concerne des composés ayant une activité au niveau du récepteur du polypeptide insulinotrope glucose-dépendant (GIP) humain. La présente invention concerne également des composés ayant une durée d'action prolongée au niveau du récepteur de GIP. Lesdits composés peuvent être utiles dans le traitement du diabète, notamment le diabète sucré de type 2 ("T2DM"). Les composés peuvent également être utiles dans le traitement de l'obésité.
Patent WO-2021022155-A1 (WO)
Inventor: DILLMAN ROBERT
IPC: G01N33/68
Filed: 2020-07-31
Abstract: Disclosed herein are methods for selecting cancer patients for autologous cancer vaccine therapy and methods for predicting survival of cancer patients after autologous cancer vaccine therapy comprising, measuring the level of soluble programmed cell death protein-1 (sPD-1) in the blood of the patient.
Patent WO-2021055114-A1 (WO)
Inventor: WANG ZHAO
IPC: H04N19/186
Filed: 2020-08-05
Abstract: La présente invention concerne un procédé et des systèmes de signalisation de décalage table de paramètres de quantification (QP) de chrominance. Selon certains modes de réalisation décrits, les procédés comprennent les étapes consistant à : déterminer si un codage résiduel de CbCr conjoint est activé ; et en réponse à la détermination de l'activation du codage résiduel de CbCr conjoint, signaliser un élément de syntaxe pour ajuster un paramètre de quantification (QP) de chrominance pour le composant de CbCr conjoint au niveau de l'unité de codage (CU).
Patent WO-2021061334-A1 (WO)
Title: Imaging system with air passage for development chamber
Inventor: MORI TADAO
IPC: G03G15/08
Filed: 2020-08-27
Abstract: An imaging system includes a housing, a developer roller that transfers developer to an image carrier at a development region, a developer regulator to limit a thickness of the developer carried on the developer roller, and an air passage that extends outside a development chamber. The air passage has an inlet to draw an airflow, and an outlet located between the developer regulator and the development region. The air passage has a cross section orthogonal to a direction of the airflow from the inlet to the outlet. In the cross section taken at the narrowest position where the air passage is the narrowest, a width in a width direction parallel to a rotational axis of the developer roller is greater than a thickness that is perpendicular to the width direction.
Patent WO-2021041720-A1 (WO)
Inventor: KLEINFELD ALAN
IPC: G01N33/92
Filed: 2020-08-27
Abstract: L'invention concerne l'identification et l'utilisation de protéines qui sont marquées par fluorescence et qui subissent un changement d'indice de fluorescence suite à une liaison à la bilirubine. L'invention concerne aussi des sondes qui sont marquées au niveau d'un résidu de cystéine ou de lysine, ainsi que des sondes marquées au niveau de la cystéine et de la lysine avec deux fluorophores différents. Ces sondes sont utilisées pour déterminer des taux de bilirubine non liée dans un échantillon de liquide.
Patent WO-2021050981-A1 (WO)
Title: Vehicular lighting using passive and/or active optics
Inventor: HONG CHANG
IPC: G02B5/12
Filed: 2020-09-11
Abstract: A reflector unit may behave as a retroreflector to reflect light of a selected color. The reflector unit may comprise a first reflector having a first color, a second reflector having a second color, and a mask that either allows incoming light to reach the first reflector and not the second reflector or allows incoming light to reach the second reflector and not the first reflector. An active light unit may emit light of a particular color in response to receiving light. In this fashion, the active light unit may simulate the operation of a reflector. The reflector unit and the active light unit may operate on a bi-directional vehicle.
Patent WO-2021055737-A1 (WO)
Title: Mems actuator system
Inventor: NG MATTHEW
IPC: G02B7/09
Filed: 2020-09-18
Abstract: A multi-axis MEMS assembly is configured to provide multi-axis movement and includes: a first in-plane MEMS actuator configured to enable movement along at least an X-axis; and a second in-plane MEMS actuator configured to enable movement along at least a Y-axis; wherein the first in-plane MEMS actuator is coupled to the second in-plane MEMS actuator.
Patent WO-2021076293-A1 (WO)
Title: Eyewear with variable compression cushion and improved moisture management
Inventor: MEUNIER BENJAMIN JOHN
IPC: A61F9/02
Filed: 2020-09-24
Abstract: A variable compression cushion for eyewear includes a lattice structure made up of lattice cells defined by lattice elements. The parameters of the lattice structure may be configured to create a desired compressibility in the cushion. Different zones of the cushion may have different compressibility. The variable compressibility enables the cushion to be configured to optimize the face pressure experienced by a user when the eyewear is worn to enhance the comfort of the user. Some embodiments of the cushion also include structures to improve ventilation through the cushion. Some embodiments of the cushion also include structures that channel moisture away from the portion of the cushion that contacts the face of the user to improve user comfort.