baber/WOPTO huggingface dataset:
Patent MX-9705309-A (MX)
Title: Analogues of n-acetylardeemin, method of preparation and uses thereof.
Inventor: DANISHEFSKY SAMUEL
IPC: A61K31/495
Filed: 1997-07-14
Abstract: The present invention provides a compound having structure (I) wherein R1, R6 and R7 are independently hydrogen, OH, NH2, SH, halogen, C1-C9 linear or branched chain alkyl, alkylmercapto, alkylamino, dialkylamino, alkoxy, phenyl, etc; wherein R0 and R2 are independently hydrogen, OH, linear or branched chain alkyl, -CR3R3-CH(O)CH2, -CR3R3-CH2CH3, -CR3R3-CH2CH2OH, -CR3R3-CH(OH)R4 or -CR3R3-CH=CHR4, wherein R3 and R4 are independently hydrogen, halogen, C1-C9 linear or branched chain alkyl, phenyl, etc; wherein R5 is hydrogen, C1-C9 linear or branched chain alkyl, phenyl, etc; an wherein R8 is hydrogen, C1-C9 linear or branched chain acyl, benzoyl, etc; with the proviso that (a) when R2 is -CR3R3-CH(O)CH2, -CR3R3-CH2CH3, -CR3R3-CH2CH2OH, -CR3R3-CH(OH)R4 or -CR3R3-CH=CHR4, then R0 is hydrogen; (b) when R0 is -CR3R3-CH(O)CH2, -CR3R3-CH2CH3, -CR3R3-CH2CH2OH, -CR3R3-CH(OH)R4 or -CR3R3-CH=CHR4, then R2 is OH; and (c) when (i) R0 or R2 is -CR3R3-CH=CHR4, (ii) R3 and R5 are CH3 and (iii) R4 is hydrogen, then R1, R6 and R7 are not all hydrogen. Also provided are related compounds and compositions, and methods of inhibiting the growth of multidrug resistant cells by means of MDR reversal, collateral sensitivity and quantitative synergism.
Patent MX-9709961-A (MX)
Title: Thrombosis risk test.
Inventor: CAMPBELL PAULA A
IPC: G01N33/50
Filed: 1997-12-09
Abstract: The present invention provides a method for determining thrombotic risk in an individual. The method involves determining the activity of Protein C and Protein S in the plasma of the individual thought to be at thrombotic risk by adding to a plasma sample obtained from the individual: (i) a first reagent in an amount sufficient to induce or activate coagulation in the plasma, (ii) a second reagent which activates endogenous protein C in the plasma, and (iii) a third reagent comprising calcium salts, phospholipids or tissue thromboplastin, or a combination thereof. To a second plasma sample from the same subject is added a reagent which induces or activates coagulation, and a buffer or other material which does not activate protein C, and a third reagent as described above. The time, rate or both, necessary for the conversion of endogenous fibrinogen to fibrin in both the first and second samples is measured. The same steps are performed on normal control plasma, and the difference or ratio in the times, rates, or both, obtained above are determined. The difference or ratio is indicative of the thrombotic risk in the subject. A kit adapted to carry out the method also is the subject of the present invention. The methods and kits of the invention in other embodiments may comprise a first reagent comprising a synthetic substrate, a second reagent which in the first sample from the subject activates protein C, and in the second sample, a second reagent which does not activate protein C. In these embodiments, the rates of hydrolysis of the synthetic substrates are measured and compared.
Patent MX-9801189-A (MX)
Title: Use of oxido-squalene cyclase inhibitors to lower blood cholesterol.
Inventor: BROWN GEORGE ROBERT
IPC: A61K31/4433
Filed: 1996-08-14
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein G, T1, T2 and T3 are selected from CH and N; provided that T2 and T3 are not both CH; A is selected from a direct bond and (1-4C)alkylene; X is selected from oxy, thio, sulphinyl, sulphonyl, carbonyl, carbonylamino, N-di-(1-6C)alkylcarbonylamino, sulphonamido, methylene, (1-4C)alkylmethylene and di-(1-6C)alkylmethylene, and when T2 is CH, X may also be selected from aminosulphonyl and oxycarbonyl; and Q is selected from (5-7C)cycloalkyl, a heterocyclic moiety containing up to 4 heteroatoms selected from nitrogen, oxygen and sulphur; phenyl, naphthyl, phenyl(1-4C)alkyl and phenyl(2-6C)alkenyl; for the manufacture of a medicament for treating diseases or medical conditions in which an inhibition of oxido-squalene cyclase is desirable.
Patent MX-9803975-A (MX)
Title: Hydrogen storage materials having a high density of non-conventional useable hydrogen storing sites.
Inventor: OVSHINSKY STANFORD R
IPC: H01M4/38
Filed: 1998-05-19
Abstract: Disordered Multicomponent hydrogen storage material characterized by extraordinarily high storage capacity due to a high density of useable hydrogen storage sites (greater than 1023 defect sites/cc) and/or an extremely small crystallite size, as shown on the graph in the figure. The hydrogen storage material can be employed for electrochemical, fuel cell and gas phase applications. The material may be selected from either of the modified LaNi5 or modified TiNi families formulated to have a crystallite size of less than 200 Angstroms and most preferably less than 100 Angstroms.
Patent MX-9805253-A (MX)
Title: Vitronectin receptor antagonists.
Inventor: ALI FADIA E
IPC: A61P19/00
Filed: 1998-06-26
Abstract: Compounds of formula (I) are disclosed which are vitronectin receptor antagonists useful in the treatment of osteoporosis.
Patent NL-2024454-A (NL)
Title: Substrate Holder for use in a Lithographic Apparatus and a Device Manufacturing Method
Inventor: JOHANNES JOSEPHUS MAASSEN
IPC: G03F7/20
Filed: 2019-12-13
Abstract: A substrate holder comprising: a main body having a main body surface; a plurality of burls projecting from the main body surface and configured for supporting the 5 substrate; and an edge seal projecting from the main body surface; wherein: the edge seal is spaced apart from the plurality of burls so as to deﬁne a gap therebetween, the gap haVing a width greater than or equal to about 75% of a pitch of the plurality of burls; the plurality of burls comprises a first group of burls and a second group of burls 10 surrounding the first group of burls; and wherein the stiffness in the direction perpendicular to the support plane per unit area of the second group of burls is greater than or equal to about 150% of the stiffness in the direction perpendicular to the support plane per unit area of the ﬁrst group of burls. 15 FIG. 4
Patent NL-2026156-A (NL)
Title: A method that adequately protects the authentic identity and personal data of a natural person and remotely confirms the authentic identity of this natural person through a trusted entity to a beneficiary party.
Inventor: HENSLEY FRANCISCO ROACH
Filed: 2020-07-24
Abstract: The proposed TDIS is a method to remotely confirm and protect the authentic identity of a _' natural person through a trusted entity, to a beneficiary party. In order to do this, the natural person sends a request with captured biometric information to the trusted entity . using a preconfigured portable device. ' Ï Before using the TDIS, the natural person must have registered with the trusted entity at A which his/her portable device has been configured for remote access to the information . system. . The complete sequence of events for getting a TDI of a natural person is as follows: . l. A beneficiary party requests authentic identification from the natural person and Ì -' the beneficiary party provides its e-mail address and out-of-band channel, such as a 15 telephone number; ‘ 2. The natural person, uses the preconfigured portable device, captures biometric : information and places a request to the trusted entity; 3. The trusted entity sends an informational message (containing no code, identifier, ~ etc.) to the e-mail address of the beneficiary party; ; 20 4. The beneficiary party visits the secured website (HTTPS) of the trusted entity, Ì creates a browser-session and submits its e-mail address; _ 5. The trusted entity creates an OTP tied to the browser-session and sends this via the ‘ _= out-of—band channel to the beneficiary party; _ 6. The beneficiary party via the same browser—session submits the received OTP to 25 the trusted entity. 7. The trusted entity compares the received OTP with the sent OTP and if they match, will provide the authentic identity information of the natural person via the browser-session to the beneficiary party.
Patent NL-2033300-A (NL)
Title: Roll-up control device for roller shade
Inventor: CHIH-YUNG WANG
IPC: E06B9/68
Filed: 2022-10-13
Abstract: A roll-up control device (4) for a roller shade (2), comprising a turntable assembly (5) comprising a turntable (51), a pull spring (52), an outer turntable (53), a shaft rod (54) and a clutch (55), and a brake assembly (6) comprising a brake shaft cover (61) fastening the shaft rod (54), a brake spring (62) sleeved on a side of the brake shaft cover (61), a compression spring (63) eXpanded and compressed inside the brake shaft cover (61), a brake sleeve (64) sleeved the side of the brake shaft cover (61) and a shaft housing (65) accommodating a damping ring (66) and clamping the brake sleeve (64).
Patent NL-285244-A (NL)
IPC: H01R13/115
Abstract: 993,900. Two-part couplings, F. HARTMANN. Nov. 9, 1962 [Dec. 5, 1961], No. 42487/62. Heading H2E. A socket comprises a flat bottom 7 with two lateral spring arms 8, bent upwardly and inwardly, the bottom having four inwardly directed embossings 7b, serving as contact elements for a flat plug 10. The bottom 7 has an inwardly directed cam-shaped embossing 7c which engages with a corresponding recess 10<SP>1</SP> in the plug.
Patent NL-6906133-A (NL)
IPC: C08J5/22
Filed: 1969-04-21
Abstract: 1,220,776. Cation exchange membranes. RHONE - POULENC S.A. 29 April, 1969 [29 April, 1968], No. 21897/69. Heading C3P. [Also in Division B1] A cation exchange membrane made of a homogeneous mixture of (a) a poly-p-vinylphenol, which is optionally halogenated, and which is cross-linked via the oxygen atoms of its hydroxyl groups and substituted by cation exchange radicals, and (b) an inert polymer may be prepared by forming a layer of a solution in and organic solvent of the inert polymer and the poly-p-vinylphenol and then, either successively or simultaneously, evaporating the solvent, cross-linking the poly-p-vinylphenol by reaction with its hydroxyl groups and introducing the cation exchange radicals. The inert polymer is one which does not interfere with the cross-linking of the poly-p-vinylphenol or the introducton of cation-exchange radicals and in particular is inert to halogenated compounds and sultones. Suitable polymers are polyvinyl chloride and a copolymer of vinyl chloride with vinylidene chloride or vinyl acetate. Cross-linking may be effected by dehydration in an inert medium containing hexamethylphosphotriamide or dioxane or by treatment of the salt of the polymer with a compound containing at least two reactive halogen atoms e.g. o- or p-xylylene dihalide or 3,3 - bis(halogeno - methyl) - oxetane. Crosslinking and radical introduction may be effected by reaction with a polysultone e.g. spirobi-2: 2<SP>1</SP>- propanesultone. Exchange radicals may be introduced by sulphonation with e.g. sulphuric acid, oleum, chlorosulphonic acid or a monosultone e.g. propanesultone. The membrane may also contain a quaternary ammonium salt and a hexaalkyl phosphotriamide. In the examples are also used poly(4 - hydroxy - 3 - chlorostyrene), poly(4 - hydroxy - 3 - bromostyrene), methyltrilaurylammonium chloride and tributyl orthophosphate.
Patent NL-7003181-A (NL)
Title: Polyantibiotic with antimicrobial activity
Filed: 1970-03-05
Abstract: The active component must be the double phosphate of N-morpholinylmethyltetracyclin (I) and oleandomycin (II). The polyantibiotic is pref. prepd. by reacting 2 equivs. of (I) with 1 equiv. of (II) in aqs. medium in the presence of phosphate buffer at pH 8. The double phosphate formed is then sterile filtered and subjected to lyophilic drying. Pref. (I) : (II) is 1.5:1. The polyantibiotic is active against tetracyclin- and oleandomycin-sensitive- as well as -resistant strains of pathogenous micro-organisms. It may be used against septic-conditions and other severe infections e.g. intravenous administration may be used against abcess-forming pneumonia, hospital-, puepural-, gynaecological- and surgical sepsis, gas gangrene and actinomycosis, etc.
Patent NL-7309440-A (NL)
Title: Resin-coated glass fibres - using phenol aldehyde condensate binder
IPC: C03C25/34
Filed: 1973-07-05
Abstract: In the manufacture of a glass fibre product by the technique disclosed in the parent Parent of allowing a large number of streams of molten glass to flow out from a series of nozzles, drawing away the streams to a desired fibre dia. depositing the fibres onto a suitable conveyor and at the same time cooling them to a temp. is not > of 175 degrees C, combining a binder with the fibres before they reach the conveyor, transporting the collected fibres and binder bonded together by hardening the binder in a hardening oven and mutually bonding the fibres and hardened binder at a contacting position, the improvement whereby (a) the resin binder consists of a phenol-aldehyde condensate produced by condensing an aldehyde and phenol in a mol.-ratio of at least 1.5: 1 in the presence of a metal-based condensing agent at pH 7.5 (approx) (b) addition to the phenolaldehyde condensate of (i) an anionic or non-ionic surfactant to the reaction mixt. in an amt. sufficient to form an emulsion and (ii) an acid in amount sufficient to adjust the pH to 7-8 before the condensation has progressed so far that pptn. of the condensate occurs at is not > pH 9.
Patent NL-7403804-A (NL)
Title: Low pressure mercury discharge lamp prodn - has mercury in container in evacuation tube, opened by mercury vapour pressure under heat
IPC: H01J9/395
Filed: 1974-03-21
Abstract: The production of a low pressure mercury vapour discharge lamp is based on a lamp tube provided with an evacuation tube, in which the quantity of mercury, required for operation, is contained in a container in the evacuation tube. The latter is heated after the evacuation, and possible gas filling, to such extent that the container opens under the force of the mercury vapour pressure produced by the heat. The container is mostly flat and so arranged in the evacuating tube that the normal evacuation and filling is not impaired. The container is preferably formed by two metal parts welded together, at least one having a dishing containing the metallic mercury prior to heating.
Patent NL-7513982-A (NL)
IPC: B41F9/00
Filed: 1975-12-01
Abstract: 1528383 Stiffening garments CODAMA HOLDING SA 25 Nov 1975 [2 Dec 1974 23 July 1975] 48428/75 Heading A3V [Also in Divisions B6 and Dl] In a process wherein patterns of cross-linkable synthetic resin are applied to both garment pieces and cured to provide local reinforcement, the resin is applied in a fluid condition by a grooved cylinder so that the resulting lines of resin provide reinforcement effectively in one direction only. For example, a jacket panel 56, Fig. 6 receives lines 57 of reinforcing material parallel to the weft direction 53.
Patent NL-7612362-A (NL)
Title: Cationic hydroxy acryloxy trialkyl ammonium esters - for making (co)polymers, and treatment of paper textiles and leather
IPC: C08F20/36
Filed: 1976-11-08
Abstract: Cationic esters CH2=CR1-COO-CH2-CHOH-CH2-NR3 + X- (I) (where R is alkyl, R1 is H or 1-3c alkyl, and X is Cl or Br), are made by reacting an aq. soln. of a glycidyltrialkylammonium halide X- (II) with an acrylic acid cpd. CH2=C(R1)-COOH (III). (I) are obtd. in higher yield and purity than in prior art processes. (I) may be (co)polymerised to give cationic resins useful for making paper with improved wet and dry strength, for creaseproofing textiles and for treating leather. The monomeric esters have surface active and germicidal properties. In an example, glycidhyltrimethylammonium chloride was reacted with methacrylic acid to give 2-hydroxy 3-methacrylyloxypropyl trimethylammonium chloride.
Patent NL-7810083-A (NL)
Title: Axial piston pneumatic motor - has distribution pipe passing through piston to cylinder head and regulator to control exhaust
IPC: F01B11/00
Filed: 1978-10-06
Abstract: The axial pneumatic motor has a piston working in a cylinder and connected to one or two parts. A distribution pipe passes through part of the piston and transfers air between opposite sides of the latter via passages extending upwards in the cylinder head. On the opposite side of the piston the air is discharged to atmosphere under the control of the governor, passing through the cylinder head and the discharge passage.
Patent NL-8001789-A (NL)
Title: Vacuum cleaner nozzle mounting - has elastic components in top most part bearing against parallel pivot axes
IPC: A47L9/06
Filed: 1980-03-26
Abstract: The vacuum cleaner nozzle has a union and a sliding shoe tilting about an axis at right angles to the reciprocating movement of the nozzle in use, so that within a defined angle it always lies flat on the surface to be cleaned. Inside the topmost part (1) of the nozzle are elastic components (10) which, when it is fitted to the lowermost part, bear against the pivot axis of the shoe (4) and also against a hinge axis (6) parallel to it. The latter axis is one part of two hinging together forming a connector hinging up and down, and for coupling to the suction pipe.
Patent NL-8005571-A (NL)
IPC: B65H54/58
Filed: 1980-10-08
Abstract: An apparatus for coiling flexible elongated materials such as tubes or cables, a composite coiling device is provided, one component (6; 14; 25) of which controls the deposit of the material in radial direction of the reel (4), an other component (5; 15; 25) fulfilling the same function in axial direction of the reel. In one embodiment of the idea of the invention there is a guiding ledge (5), a side face of which keeps the axial control, the main body of the ledge providing the necessary radial force, particularly in that it is backed by a swinging plate which is under spring tension in radial direction. The ledges move over the entire width of the plate, equal to the reel width, and the friction between the two is adjustable. In an other embodiment the composite guiding device comprises one component in form of a radial expandability of parts (14) of the reel core, the other component being a set of pivoting arms (15) movable between a retracted position and one in which they are radial and confine the coil. In a third embodiment the composite guiding device is a guiding eye (25) mounted with three degrees of freedom.
Patent NL-8101674-A (NL)
IPC: A61C8/00
Filed: 1981-04-03
Abstract: The invention relates to a new implant material of ceramic material for use in dentistry and medicine for replacing hard tissue, such as dental elements and bones. In order that the material may have sufficient strength characteristics, in particular tensile and bending strength, there is provided a compression element with which the ceramic material, preferably sintered hydroxylapatite, can be brought under compression.
Patent NL-8103982-A (NL)
Title: EM actuator for motor - has one-piece-permanent magnet with central zone of opposite polarity to that of outer zones
IPC: H04R9/02
Filed: 1981-08-27
Abstract: This electromagnetic actuator consists of a coil (2) wound at right angles to and concentric with a central axis (3), separated by an air gap (6) from an axially magnetised permanent magnet. The permanent magnet consists of a single magnetic body (12), so magnetised that the polarity of the central zone (14) is opposite to that of the outer zones (13A,13B). Contact with the coil winding is made by loose leads with clamping connectors (4,5) at the free ends. This actuator is cheaper to make than ones built up from two or more magnetic bodies, and has more predictable characteristics.
Patent NL-8105533-A (NL)
Title: Thermographic foil with untreated heat-sensitive liquid crystals - between carrier and transparent foil with selected heat conductivities
IPC: G01K11/16
Filed: 1981-12-08
Abstract: The thermographic foil comprises a carrier provided with limited blackened areas, a layer of liquid crystals (particularly esters of cholesterol), which change colour in response to heat, applied to the carrier, and a gas-impermeable transparent cover foil. The layer consists of liquid crystals which are not micro-encapsulated or otherwise pre-treated and without any additives, and is enclosed with the exclusion of oxygen between the carrier and the cover foil applied by cold pressing. The carrier and the cover foil are in materials with pre-determined thermal conductivities. The carrier and cover foil may have high and low thermal conductivity respectively or vice versa, or they may both have high or low conductivity. Thermographic foil usable for temperature measurements of solid components or gas flows, for decorative purposes, e.g. as wall covering (with controllable heating facility), for packing (to change colour when handled) or advertising purposes, etc..
Patent NL-8200870-A (NL)
Title: One-piece plastics band clamp - has two straps each extending from stem and including interengageable and lockable ratchet teeth, straps adapted to surround cable
IPC: F16L3/12
Filed: 1982-03-03
Abstract: The one-piece plastics band clamp includes a stem (1) to be inserted into a hole in a support and two straps (4,5) attached to one end of the stem and extending in spaced relationship. Locking equipment is disposed on the end of strap member (5) remote from the stem. The locking equipment includes an open-ended passage having ratchet teeth (15). The other strap (4) has ratchet teeth (14) complementary to the ratchet teeth (15) for engagement in any one of a number of relative positions to retain cables or conduits. The stem (1) pref. has a core with four longitudinal rows of flexible fins (24) and may be located on a head (6) offset from the side of the clamp.
Patent NL-8203076-A (NL)
Title: Tractor-drawn spinach mowing machine - has endless transporter belts, moving spinach through opening then forming swath
IPC: A01D45/28
Filed: 1982-08-02
Abstract: The mowing beam (3) has two rows (4,5) of cutting knives. The top row (4) is movable back and forwards via a PTO and drive pulleys (6) w.r.t. the bottom row of knives (5). The spinach stalks are cut between the reciprocating knives. After mowing, the spinach is heaped on the mowing beam in front of transporter belts (11,12). The endless transporters are spaced to leave an opening (13) and run counter clockwise. A swath (16) is formed after the spinach passes an opening (13). The transporter belt transmission is via an hydraulic motor (17) and V-belt units. The transporter belts may have an equispaced peripheral mounted spike which improves output.
Patent NL-8204608-A (NL)
Title: Near-spherical cheeses lifted from brine bath - are placed in single row, orientated, and transferred to carriers for moving into store
IPC: A01J25/16
Filed: 1982-11-26
Abstract: Arrangement is claimed for moving approx. spherical cheeses (with flattened polar regions but longer polar axis than equatorial dia., i.e. Edam-type cheeses) from the brine bath on to carriers and then to the maturing store, and passing them through a plastic coating unit if required. They first pass through a buffer store unit comprising a horizontal endless belt with an oppositely moving belt to either side, two belts moving horizontally in vertical planes at the belt entry to return cheeses from the belts to the central belt, and two sets of vertically spaced rollers at the exit to position the cheeses in a single row. After passing through the unit, a slatted belt loads the cheeses on tracks each consisting of two parallel endless transport chains with double-conical rollers between them drivable to orientate the polar axes parallel to the roller axes. The cheeses are then rotated as required to get all labels on the same side, and transferred to the carriers by lateral rotation through 90 deg. Used for transferring near-spherical cheeses from brine bath to carriers for moving into maturing store, plastic coating them on the way and placing them with labels uppermost on the carriers. Arrangement completely mechanises otherwise very labour-intensive manual handling operations.