baber/WOPTO huggingface dataset:
Patent CA-2672805-A1 (CA)
Inventor: KONKEL MICHAEL
IPC: C07D403/14
Filed: 2002-01-31
Abstract: This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier.  This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and apharmaceutically acceptable carrier.  This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist.
Patent CA-2676509-A1 (CA)
Title: Stabilization of thermolysin in aqueous solution
Inventor: HOELKE WERNER
IPC: C12N9/96
Filed: 2009-08-24
Abstract: The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form.
Patent CA-2678648-A1 (CA)
Title: Siting plan systems and methods
Inventor: NICOLUCCI ROBERT
IPC: E04G21/00
Filed: 2009-09-14
Abstract: Systems and methods for siting at least one model on a siting plan.  The system may include: a site plan database and a siting generator operatively coupled to the site plan database. The site plan database may include at least one layout record corresponding to a site plan having a set of at least one lot.  The siting generator is configured to generate a siting plan corresponding to the layout record. The siting generator may be configured to determine a plurality of lot boundaries on the siting plan, with each lot boundary corresponding to at least one lot on the siting plan. The siting generator may further be configured to determine a model/lot siting corresponding to a combination of a model and a lot on the siting plan.
Patent CA-2679053-A1 (CA)
Title: Fastening system for sheathing board
Inventor: HAUBER ROBERT J
IPC: F16B15/08
Filed: 2007-06-15
Abstract: Disclosed is a fastening system that is adapted for securing a sheathing board to an associated framing member. The system includes a feedband for retaining a series of fasteners and a powered drill for sequentially driving the fasteners. The feedband is made from a membrane of a polymeric compound. As the fastener is driven into the sheathing board, a portion of the membrane tears away from the surrounding feedband and becomes seated beneath the fastener. This acts to seal the penetration point and prevent water intrusion and otherwise prevents deterioration of the sheathing board.
Patent CA-2679360-A1 (CA)
Inventor: DEGUET CYRIL
IPC: H04L47/30
Filed: 2008-02-15
Abstract: A method and system is provided for routing data in a system. The method includes determining an initial fixed distribution pattern, determining a queue parameter based on at least a current amount of system use and a maximum potential system use, determining a time parameter based on the time that a message in the application has been waiting for its processing, determining a load parameter based on at least the time parameter and the queue parameter, and modifying the distribution pattern based on at least the load parameter.
Patent CA-2679849-A1 (CA)
Title: Functionally selective alpha2c adrenoreceptor agonists
Inventor: YU YOUNONG
IPC: C07D417/14
Filed: 2008-02-11
Abstract: In its many embodiments, the present invention provides a novel class of indolines as inhibitors of .alpha.2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the .alpha.2C adrenergic receptors using such compounds or pharmaceutical compositions.
Patent CA-2680668-A1 (CA)
Title: Link apparatus, weighing apparatus using link apparatus, packaging apparatus using link apparatus and weighing and packaging system using link apparatus
Inventor: KAWANISHI SHOZO
IPC: B65B9/08
Filed: 2008-03-12
Abstract: Provided are a link apparatus which is capable of supplying objects to be weighed which have been discharged from a weighing machine to package bags being conveyed successively at a high speed, a weighing apparatus using the link apparatus, a packaging apparatus using the link apparatus, and a weighing and packaging system using the link apparatus. A link apparatus of the present invention comprises plural funnel-shaped chutes which are respectively supplied with objects to be weighed through entrances at upper portions thereof and respectively discharge the objects to be weighed through exits at lower portions thereof; and a rotary board which conveys the plural chutes along a revolving path in a state where the exits of the respective chutes are arranged in one line in a direction along the revolving path, the revolving path including a first area under which package bags arranged in one line are conveyed in the direction along the revolving path, the first area being a part of the revolving path; wherein the entrances of the chutes are formed by openings which are elongated in the direction along the revolving path; and wherein the rotary board is configured to convey the chutes such that the exits of the chutes are respectively located above the package bags in the first area.
Patent CA-2681469-A1 (CA)
Inventor: BAKER MYLES L
IPC: F03D11/04
Filed: 2007-09-13
Abstract: A lightweight wind turbine blade formed with a truss support structure assembly of composite truss joints including composite spar and cross members attached to and supporting in spaced relation a spine of lightweight rib panels. The rib panels are oriented in parallel spaced relation from one another and individually molded with perimeters defining individual areas of curvature for the finished blade assembly. The truss support structure is covered with a lightweight fiberglass or hardened fabric skin attached to and fitted on respective rib panel edges forming an airfoil structure.
Patent CA-2685269-A1 (CA)
Title: Carbohydrate-lipid constructs and their use in preventing or treating viral infection
Inventor: HENRY STEPHEN MICHEAL
IPC: A61P31/12
Filed: 2008-04-28
Abstract: The invention relates to selected carbohydrate-lipid constructs and their use as mimics of ligands for receptors expressed by a virus. In particular, the invention relates to the use of selected carbohydrate-lipid constructs in methods of inhibiting virus infection and/or promoting clearance of virus from infected subjects. Carbohydrate-lipid constructs selected for use in these methods where the virus is Human Immunodeficiency Virus (HIV) are provided.
Patent CA-2687163-A1 (CA)
Title: Method and system for automatically keeping travel data consistent between passenger reservation records and corresponding electronic tickets
Inventor: DEFAYET CHRISTOPHE
IPC: G06F17/30
Filed: 2008-05-07
Abstract: A method and a system are described that keep travel data consistent between a database of airline reservations storing passenger name records (PNR's) comprised of travel segments, and a database of electronic tickets (E-tickets) comprised of travel coupons, this latter database being independently controlled from a ticketing server. Whenever a travel segment is updated or added in one of the PNR's an electronic reconciliation service (ERS) receives images of updated PNR's. Corresponding E-ticket images are requested by ERS and received from the database of E-tickets. Then, ERS establishes a matrix of links between orphan PNR travel segments and orphan E-ticket travel coupons so that E-ticket orphan travel coupons are re-associated with matching PNR orphan travel segments. After E-ticket is updated it is revalidated or reissued. Optionally, if applicable, a penalty generator is requested to calculate penalty fees on the basis of changes brought to the revalidated or reissued E-tickets. The penalty fees are then attached to the updated PNR's.
Patent CA-2689591-A1 (CA)
Inventor: GROMPE MARKUS
IPC: C12N15/861
Filed: 2008-06-05
Abstract: Described herein is a method of expanding human hepatocytes in vivo using an immunodeficient mouse which is further deficient in fumarylacetoacetate hydrolase (Fah). The method comprises transplanting human hepatocytes into the immunodeficient and Fah-deficient mice, allowing the hepatocytes to expand and collecting the expanded human hepatocytes. The method also allows serial transplantation of the human hepatocytes into secondary, tertiary, quaternary or additional mice. Also provided are mutant mice comprising homozygous deletions or point mutations in the Fah, Rag2 and 112rg genes.
Patent CA-2691037-A1 (CA)
Inventor: LOBZAKOV YURIY
IPC: H04L27/26
Filed: 2010-01-25
Abstract: A service management platform for processing packet switched communications is provided. The service management platform has a component for handling voice calls. The component for handling voice calls comprises a first input/output for sending and receiving data packets associated with a first leg of a call, a second input/output for sending and receiving data packets associated with a second leg of the call, a monitoring component for monitoring copies of the data packets for commands contained within a payload of the data packets, and a relay component for directly relaying the data packets between the first input/output and the second input/output and for generating and forwarding copies of the data packets to the monitoring component.
Patent CA-2695010-A1 (CA)
Inventor: PELLETIER GHYSLAIN
IPC: H04L47/32
Filed: 2008-07-03
Abstract: Packets are selectively marked or dropped when congestion of the radio resources is experienced, the selective marking/dropping being related to or dependent on the probability that a packet will be marked with the relative efficiency of usage of the radio link by the receiver, e.g., dependent upon radio resource usage costs and fairness. For example, packets are marked or dropped based on a user's associated share of the total (or a subset of the) shared radio resources. This share may be expressed in terms of the costs of the resources in terms the user's level of utilization of the shared resources, or in terms of it's fairness with respect to other users sharing the same resources. Thus, the present technology takes into account the distribution of resources usage between receivers contributing to the congested state of the radio network.
Patent CA-2695411-A1 (CA)
Title: Injection device with locking mechanism for syringe carrier
Inventor: JENNINGS DOUGLAS IVAN
IPC: A61M5/32
Filed: 2008-07-28
Abstract: An injection device comprises a locking mechanism (171-173) between a syringe carrier (127) and an end cap (111) of the injection device. The cap is formed in such a way to inhibit movement of the syringe carrier and syringe towards an exit aperture of the injection device when the drive has not been removed from the injection device. On removal of the cap, the locking mechanism is no longer so engaged and the syringe and syringe carrier can move towards the exit capture. This assists in preventing damage to the syringe prior to actuation of the injection device.
Patent CA-2695934-A1 (CA)
Title: Cowl top panel and front vehicle body structure for automobile
Inventor: ISHII KENJI
IPC: B60S1/34
Filed: 2009-01-27
Abstract: A main bent portion 25 is formed at a center portion of a cowl top outer panel 14 with respect to a vehicle longitudinal direction so as to extend linearly along a vehicle widthwise direction. The main bent portion 25 is formed by a lower flange portion 18, an upright portion 19 and a lower flat portion 20. The lower flange portion 18 and the upright portion 19 are perpendicular to each other, and the upright portion 19 and the lower flat portion 20 are perpendicular to each other. A lower flange portion 18, a lower flat portion 20 and an upper slanted portion 23 are provided to the cowl top outer panel 14 so as to support a front end portion and a rear end portion of a first bracket 27 and a second bracket 28 of a wiper unit 30. The lower flange portion 18, the lower flat portion 20 and the upper slanted portion 23 are arranged in this order along the vehicle longitudinal direction of the main bent portion 25.
Patent CA-2697358-A1 (CA)
Title: Balloon mitral spacer
Inventor: ELIASEN KENNETH ARDEN
IPC: A61F2/24
Filed: 2008-05-14
Abstract: A heart valve implant according to one embodiment may include a shaft and an anchor disposed on one end of the shaft, the anchor configured to engage tissue. The heart valve implant may further include an expandable member disposed over at least part of the shaft, the expandable member comprising a resiliently deformable internal layer and a resiliently deformable external layer disposed over the internal layer, the expandable member defining a chamber and being configured to receive an inflation medium in the chamber to expand the expandable member, the expandable member further configured to deform upon contact with at least a portion of at least one leaflet of a heart valve to at least partially conform to the shape of the leaflet.
Patent CA-2698059-A1 (CA)
Title: Access devices
Inventor: SHELTON FREDERICK E IV
IPC: A61B17/34
Filed: 2010-03-30
Abstract: Various devices and methods are provided with respect to inserting multiple surgical instruments through a single surgical access device. A medical device including a flexible tissue retractor and a releasable insert having multiple instrument openings is disclosed. The insert can be in the form of an insert assembly including multiple components. A method of using the insert is also described.
Patent CA-2698702-A1 (CA)
Inventor: STUDER ROGER
IPC: A61C8/00
Filed: 2008-09-16
Abstract: The present invention relates to a connection arrangement between a dental implant (1) and an abutment (2) comprising an abutment (2) having a first coronal opening (23) and a second apical opening (24), a screw (3), and a ring (4), the ring (4) being suitable for holding a screw (3) inserted in an abutment (2), characterized in that the ring (4) is fixed in the first opening (23) of the abutment (2) with a positive fit or bond.
Patent CA-2703204-A1 (CA)
Inventor: DEUTSCH JONATHAN PETER
IPC: G06F13/00
Filed: 2008-10-24
Abstract: A method, apparatus, and system are described for a central management system to configure remote devices. A device service manager server (DSM) may have an IP redirector module configured to cooperate with two or more device service controllers (DSCs) that are behind a firewall on a wide area network relative to a location of the DSM on the wide area network, where the DSM serves as a central management station for a distribution of initial configuration information to the DSCs, wherein an executable boot up file uploaded via a drive port in that DSC is scripted to gather configuration information for that DSC and network devices on the same network as that DSC and without a prompt by the DSM then sends configuration files to the DSM which makes a master copy of the device configuration file in the DSM's registry for that DSC.
Patent CA-2704149-A1 (CA)
Inventor: HAPSARI WURI ANDARMAWANTI
IPC: H04W92/20
Filed: 2008-10-30
Abstract: A radio base station (T-eNB) according to the present invention is configured to set up a data forwarding tunnel for forwarding user plane data to the radio base station (T-eNB) only for an access bearer for which the user plane data to be forwarded exists, when receiving a notification from a handover-source radio base station (S-eNB) as to whether or not the user plane data to be forwarded exists for each access bearer, the notification being made by using a handover request message for the mobile station (UE), and the access bearer being set up between the radio base station (T-eNB) and a upper level node (SGW); and
Patent CA-2704939-A1 (CA)
Inventor: GALES NICOLAS
IPC: B60T17/04
Filed: 2008-11-12
Abstract: Embodiments of a hydraulic brake system (100,300) are disclosed. In one embodiment, a priority flow control valve (112, 312) for supplying operating pressure has a first orientation in which operating pressure is provided at a controlled flow port (118, 318) and a second orientation in which operating pressure is provided at the controlled flow port and an excess flow port (119, 319). A steering control unit (114, 314) has an inlet port (120, 313) for receiving operating pressure and an outlet port (122, 322) for communicating a steering control load sense signal. A brake control unit (116, 316) has an inlet port (130) for receiving operating pressure and an outlet port (138) for communicating a braking control load sense signal. The inlet port (130) of the brake control unit and the inlet port (120, 313) of the steering control unit are connected to the controlled flow port (118, 318).
Patent CA-2708303-A1 (CA)
Inventor: CLAREMON DAVID A
IPC: C07D413/12
Filed: 2008-12-10
Abstract: This invention relates to novel compounds of the Formula (I), (Ia) and (Ib), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, j which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 .beta.-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell Or the inhibition of the conversion of cortisone to Cortisol in a cell.
Patent CA-2708926-A1 (CA)
Inventor: REIDY KATHLEEN
IPC: A23L33/00
Filed: 2008-12-23
Abstract: The present invention provides a nutritional methodology for optimizing the nutritional needs of a child that includes suggested combinations of food products from a range of foods having an optimal nutrition profile for meeting the nutritional needs of a child wherein two or more food products from the range may be combined to provide an optimal nutrition profile for meeting the nutritional needs of a child. The present invention further provides a kit and a shelf-stable product that employ the nutritional method for optimizing the nutritional needs of a child.
Patent CA-2710388-A1 (CA)
Inventor: BECKER DAVID L
IPC: A61K31/7088
Filed: 2008-12-22
Abstract: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.
Patent CA-2714260-A1 (CA)
Inventor: HWANG CHARLES G
IPC: A61B19/02
Filed: 2010-09-01
Abstract: A shipping container integrates a sharps disposal container with a new product storage container for shipping. The storage container stores new product. A sharps disposal container receives used sharps. One of the storage container and the sharps disposal container is disposed within the other of the storage container and the sharps disposal container for shipping. A lid is adapted to be connected to the outermost container of the sharps disposal container and the storage container for shipping and to a top of the sharps disposal container for receiving used sharps.
Patent CA-2723342-A1 (CA)
Title: Nouvelles compositions depigmentantes anhydre comprenant un derive phenolique solubilise
Inventor: MALLARD CLAIRE
IPC: A61K47/14
Filed: 2009-06-02
Abstract: La présente invention concerne une nouvelle composition dépigmentante anhydre notamment pour une application topique, comprenant, à titre d'actif pharmaceutique, un dérivé phénolique solubilisé dans la phase grasse, à son procédé de préparation et à son utilisation en dermatologie.
Patent CA-2724112-A1 (CA)
Inventor: CARELLA LEONARDO
IPC: A23G9/32
Filed: 2010-12-07
Abstract: The present matter provides a gelato formulation that is low in carbohydrate, high in protein, and fiber enriched having similar taste, body and texture of traditional gelatos, and a method of making the same.
Patent CA-2725987-A1 (CA)
Title: Low index, large mode field diameter optical coupler
Inventor: WEBSTER MARK
IPC: G02B6/26
Filed: 2009-05-28
Abstract: An optical coupler is formed of a low index material and exhibits a mode field diameter suitable to provide effi-cient coupling between a free space optical signal (of large mode field diameter) and a single mode high index waveguide formed on an optical substrate. One embodiment comprises an antiresonant reflecting optical waveguide (ARROW) structure in conjunc-tion with an embedded (high index) nanotaper coupling waveguide.  Another embodiment utilizes a low index waveguide structure disposed in an overlapped arrangement with a high index nanotaper coupling waveguide. The low index waveguide itself includes a tapered region that overlies the nanotaper coupling waveguide to facilitate the transfer of the optical energy from the low index waveguide into an associated single mode high index waveguide.
Patent CA-2727275-A1 (CA)
Inventor: BENVENUTI CRISTOFORO
IPC: F24S10/70
Filed: 2008-06-11
Abstract: Evacuated solar panel (1) comprises a frame (2) carrying spacers (3,4) crossing one another and one or two trans-parent walls (10, 10a) connected to said frame (2) and defining with said frame (2) an evacuated closed chamber (11). The cham-ber (11) contains the longitudinal and transverse spacers (3,4) and an absorber (14) comprising a plurality of absorbing panels (14a, 14b) each connected to a cooling pipe (15) welded to the frame (2) at both extremities. The longitudinal spacers (3) are in contact with the transparent wall (10) to support it against the ambient pressure, while the transverse spacers (4) support the longi-tudinal sides of the frame (2) against the ambient pressure and are not in contact with the transparent wall (10), so allowing the ab-sorbers (14a, 14b) to cover the whole length of the panel (1) without interruptions.
Patent CA-2728011-A1 (CA)
Inventor: LANGFORD LAWRENCE W
IPC: B60S1/54
Filed: 2011-01-17
Abstract: A method for clearing precipitation off a front windshield which includes placing more than one vortex generator forward of the front windshield to re-energize air as it approaches the windshield so that airflow drives precipitation from the windshield. This method has particular application to aircraft windshields.
Patent CA-2729552-A1 (CA)
Inventor: YUAN HAIQING
IPC: C07D471/04
Filed: 2009-06-30
Abstract: The present invention provides compounds having the formula: (I), (II), Wherein n is I or 2; m is 0 or 1; p is 0, 1 or 2; R1 is aryl, heteroaryl or alkyl: R2 is C1-6 hydrocarbyl, alkylacyl or hydroxyalkyl; R3 is aryl, heteroaryl, or alkyl; R4 is H, OH, --O-(C1-6 alkyl), -NH-(C1-6 alkyl), or oxide; R5 is H, halogen, C1-6 alkyl, O-(C1-6 alkyl), aryl, heteroaryl, -C(=O)(C1-6 alkyl), substituted or un-substituted oxazolin-2-yl; X = 0, NH -C(=0)- or -N=CH-; and Each L is independently alkylene and carbonyl. This compounds are SI P antagonists useful for treating a disease selected from: glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wounds, and pain.