baber/WOPTO huggingface dataset:
Patent AT-E352901-T1 (AT)
Inventor: DUEME PHILIPPE
IPC: H03F3/60
Filed: 1999-12-23
Granted: 2007-02-15
Abstract: The device comprises a multiple structure of distributed amplifiers (AD1, AD2) with switching elements (T1,T2), connected between the gate lines (Lgc1, Lgc2) and the drain lines (Ldc1, Ldc2). At least one switching element is active and controlled as a function of the control bit of the cell by the bias controllers (C1,C2). The active switching element between the gate line and the first drain line (Ldc1) is biased in amplifier mode, and that between the gate line and the second drain line (Ldc2) is biased in holding mode, and vice versa. The input (12) is connected to the gate line, and the output to the input of the next distributed amplifier forms the common gate line (10). The outputs (14,16) of distributed amplifiers as terminals of the drain lines (Ldc1, Ldc2) are connected to a summation device (18) with output (19) connected to a load (21) of 50 Ohm, terminating the line of programmable length for 1 bit.  The summation device (18) can be active or passive, and its connection forms an auto-recombining structure. In another embodiment, the device contains two sets of double distributed amplifiers (AD1, AD2) connected in series to form a quadruple distributed amplifier (QAD), an an additional summation device receiving inputs from two summation devices making a line of programmable length for 2 bits. The device comprises a number of simple-structure distributed amplifiers (AD1, AD2, AD3, ...) with the common gate line, connected in series directly or indirectly to form a line of programmable length for several bits. The number of delay states determined by the number of distributed amplifiers determines the number of bits; two for 1 bit, four for 2 bits, etc. The device can contain the gate lines connected via passive delay elements. The active switching element is a transistor (T) of type field-effect, bipolar heterojunction, or analogous. The device can be realised by the monolithic microwave integrated circuit (MMIC) technology, and can operate in a very wide frequency band up to several tens of GHz, e.g. 1-20 GHz.
Patent AT-E209465-T1 (AT)
Inventor: ROBINSON STEPHEN ELLIS
IPC: A61B5/05
Filed: 1999-01-20
Granted: 2001-12-15
Abstract: A method of performing synthetic aperture magnetometery on the signals from a target organ using an array of biomagnetic sensors positioned in a predetermined manner around the target organ, each sensor in the array having a position vector and an orientation vector relative to a common coordinate system encompassing the target organ. The method includes the steps of: simultaneously measuring EM signals from each sensor positioned in the array for a selected time interval; computing a covariance matrix of the measured EM signals over a user-selected time sub-interval within the selected time interval; selecting a set of coordinates for a region of interest to be imaged and a distance between voxels to form a grid of voxels; computing a forward solution for a current element at each of the voxels for each of the sensors in the array sensors; computing an RMS current density estimate for each voxel from the covariance matrix and the forward solution for that voxel; and displaying the voxels estimating RMS current density as a first image. The method is particularly well suited for evaluating brain activity in a human subject.
Patent AT-E329605-T1 (AT)
Inventor: KHARAZMI ARSALAN
IPC: A23L1/30
Filed: 1999-04-16
Granted: 2006-07-15
Abstract: A formulation having a rose hip concentrate is used to treat and/or alleviate the symptoms associated with inflammation including arthritis or to prevent development of arthritis. The rose hip concentrate has a high vitamin content relative to conventionally dried material, and is shown, in vitro, to inhibit the chemotaxis and oxidative burst response of human peripheral blood inflammatory cells, as well as the chemotaxis of monocytes. The formulation, in vivo, was found to inhibit chemotaxis of human peripheral blood inflammatory cells and to reduce the level of C-reactive protein, to alleviate pain and reduce inflammation in patients with arthritis.
Patent AT-E233651-T1 (AT)
Inventor: VAN ERT JACK M
IPC: B29C51/20
Filed: 1999-03-26
Granted: 2003-03-15
Abstract: A method for forming a vehicle headliner comprises providing at least one layer of formable material and a cover member; heating the layer and the cover member; providing a mold having a pair of mold halves and a compressible seal disposed between the mold halves, at least one of the mold halves having an aperture and a channel in communication with the aperture; positioning the layer and the cover member between the mold halves; bringing the mold halves toward each other to effect a sealed relationship; and applying a vacuum pressure to the aperture to sufficiently draw the mold halves together and compress the seal, thereby compressing the at least one layer and the cover member together to form the headliner.
Patent AT-E246655-T1 (AT)
Inventor: DEMMELER ERWIN
IPC: B65H3/62
Filed: 1999-05-11
Granted: 2003-08-15
Abstract: An apparatus for singling sheetlike data carriers is proposed wherein the stack (30) to be singled is located on a rest (5) which is movable relative to a feed device (4) in clocked fashion such that individual data carriers are moved in the direction of a singling gap whose width is variable by a retaining element (13) in synchronism with the clocked motion of the rest (5). This apparatus is able to attain a high throughput even with different sheet qualities while guaranteeing high functional safety.
Patent AT-E293149-T1 (AT)
Inventor: RING JOHN
IPC: C09D5/03
Filed: 1999-07-02
Granted: 2005-04-15
Abstract: A powder coating composition of the invention comprises a film-forming polymeric component having a d(v,50) in the range or from 25 to 50 microns or a d(v,70) in the range of from 25 to 70 microns, which composition incorporates by dry-blending at least one appearance-modifying additive component and a further component comprising wax-coated silica or consisting of alumina together with aluminum hydroxide. The appearance-modifying additive may be a gloss-reducing component, a texturing component, a metallic or mica component, a coloring pigment, or a further film-forming polymeric material comparable with the first film-forming polymeric material and differing in coloration therefrom, and the further additive may be alumina together with aluminum hydroxide, wax-coated silica, or a combination thereof. Preferably, no more than 70% by volume of the particles in the film-forming polymeric material are less than 50 microns. A kit of the invention comprises the individual additive components prior to mixing. The kit allows for the flexible production of a variety of finishes from a gloss powder coating composition, for example, a matte, textured, metallic, or sparkle finish, a matte metallic finish, an antique finish, or a contrast texture or metallic sparkle finish.
Patent AT-E298178-T1 (AT)
Inventor: GILHOUSEN KLEIN S
IPC: H04B1/04
Filed: 1999-02-19
Granted: 2005-07-15
Abstract: A system and method is taught for controlling the power level of transmissions within a communication system having a base station, a mobile station, a communication channel, and a pilot channel. The mobile station determines a signal strength value according to a communication signal received by way of the communication channel. A pilot channel signal is determined according to a pilot signal transmitted by way of the pilot channel. The signal to noise ratio of the communication signal is determined according to the determined signal strength value and the pilot channel signal. The power level of a transmission is controlled according to the signal to noise ratio. The noise level in a communication channel within the communication system is estimated. The pilot channel signal includes pilot energy and pilot noise components. The pilot energy component is removed to provide a remaining pilot signal. Communication system operations are controlled according to the remaining pilot signal. The power levels of transmissions are controlled by determining the signal to noise ratio of a signal within the communication channel and determining a difference signal. The difference signal is formed by determining the difference between determined and desired signal to noise ratios. The difference signal is transmitted between the base station and the mobile station. The pilot channel has at least one frame and the power control signal is inserted into the frame. Thus, information representing the strength of the communication signal is transmitted to the base by way of the pilot channel within the frame. The pilot channel can have two information frames for transmitting the power control signal a plurality of times.
Patent AT-E250481-T1 (AT)
Inventor: GYSI PETER
IPC: B21C37/08
Filed: 1999-08-19
Granted: 2003-10-15
Abstract: A tube welding machine (1) is of modular construction, the individual modules (2, 3, 4, 5) being arranged on a common support rail (6).
Patent AT-E241514-T1 (AT)
Inventor: WORSOEE CHRISTOFFER
IPC: B65D19/12
Filed: 1999-10-04
Granted: 2003-06-15
Abstract: Collapsible container comprising a bottom element ( 11 ) with openings ( 21 ) at the corners for disengagable attachment of two opposite gable walls ( 12, 13 ). The gable walls are connected to or are associated with supporting pillars ( 24 ) which are provided with slit shaped openings ( 31 ) for disengagable mounting of longitudinally arranged sidewall elements ( 14, 15 ) which have projecting hooks ( 28, 29 ) with notches ( 30 ) for engagement with the slit-shaped openings. Openings ( 39-44 ) are arranged in the bottom element ( 11 ) for disengagable attachment of a transversal partition wall ( 36 ). The sidewall elements ( 14, 15 ) each have a height dimension (A) which is one half of the width of the bottom element ( 11 ). The distance (B) between two sidewall elements ( 14, 15 ) is less than the depth of the notch ( 30 ) in the hooks ( 28, 29 ). The corner posts ( 22 ) of the gable walls ( 12, 13 ) are manufactured with a tubular profile with attachment slit openings ( 31 ) facing inwards, for attachment of shelves ( 33 ). The collapsible container also includes supporting pillars or side posts ( 16, 17 ) with a projecting flange in both sideward directions, these flanges being provided with slit-shaped openings ( 42 ) for attachment of shelves ( 33 ).
Patent AT-E298035-T1 (AT)
Inventor: KUMLIN JERRY
IPC: E04B1/68
Filed: 1999-12-10
Granted: 2005-07-15
Abstract: The present invention relates to a process for the manufacture of expandable elements having a determined shape, whereby a mass (1) consisting of organic fibres, which are expandable by the addition of a hydrophilic liquid, is compressed in one or more determined directions to a density of 300 to 1500 kg/m<3>, preferably 600 to 800 kg/m<3>, and that elements having the determined form are shaped from said mass, as well as an expandable element and its use.
Patent AT-E235307-T1 (AT)
Inventor: NOACK ANDREAS
IPC: B01D17/00
Filed: 1999-10-26
Granted: 2003-04-15
Abstract: The invention relates to a method for separating a fluid mixture consisting of at least two components. The inventive method comprises the following steps: contacting the fluid mixture at a first, lower temperature in a first operating zone with a carbon membrane which is arranged adjacent to a surface of a porous transport matrix or which is applied on a surface of the matrix, whereby at least one fluid component is adsorbed and at least one component of the fluid mixture preferably permeates the membrane; heating a surface spatially distant from the membrane and/or a part of the porous transport matrix to a second, higher temperature which facilitates the thermal desorption of adsorbed components in a second operating zone; separately removing the fluid mixture depleted by the at least one permeated component from the first operating zone and the fluid mixture enriched with the at least one permeated component from the second operating zone. The invention also relates to a device for carrying out the inventive method.
Patent DE-1231054-T1 (DE)
Inventor: NISHIZAWA TAKATOSHI
IPC: B32B37/15
Filed: 2002-02-08
Abstract: To provide a stretched film of void-containing thermoplastic resin having an attractive force between sheets is 50 g or less. The stretched film of void-containing thermoplastic resin has no charge therein and can be processed secondarily with lesser electrostatic disturbance even in a low-humidity environment.
Patent DE-603343-T1 (DE)
Inventor: PERSSON JOHNNY
IPC: B26D7/01
Filed: 1992-09-08
Abstract: The invention relates to a method and apparatus for punching register holes in sheets provided with adjustment marks. The apparatus comprises a punching table (1) having punches (27) and sensors (28) on the punching table, a vacuum table (25) being provided in the punching table substantially in the plane thereof, said vaccuum table being adjustable in two mutually perpendicular directions in the plane of the punching table and being rotatable about an axis perpendicular to said plane. Adjustment means for the adjustment of the vacuum table are operatively connected to the sensors to control the operation thereof via a microprocessor in dependence of the adjustment marks being sensed by the sensors. When the method is practised the sheet is attached by suction to the vacuum table, and this table and thus the sheet is positioned by the adjustment of the vacuum table, the positioning being controlled in dependence of the position of the adjustment marks being sensed. After positioning the sheet is punched, the sheet then being released from the vacuum table and removed from the punching table.
Patent ES-2160557-T1 (ES)
Title: Cinta textil adhesiva.
Inventor: LODDE CHRISTOPH
IPC: C09J7/21
Filed: 2000-12-01
Abstract: Cinta textil adhesiva formada por un soporte de cinta adhesiva (1), de un material textil, no tejido, fijado mecánicamente, con por lo menos un recubrimiento en una cara (2), caracterizado por el hecho de que el material no tejido posee un peso por unidad de superficie, menor o igual a 60 g/m2 y está impregnado con una resina termoplástica.
Patent ES-2850173-T1 (ES)
Title: Resistencia a Peronospora en Spinacia oleracea
Inventor: DEN BRABER JAN HUGO
IPC: C12N15/82
Filed: 2012-10-26
Abstract: Planta de espinaca que comprende un único gen dominante que confiere resistencia a Peronospora farinosa f. sp. spinaciae razas Pfs1, Pfs2, Pfs3, Pfs4, Pfs5, Pfs6, Pfs9, Pfs11, Pfs12, Pfs13 y UA4410, en las que el gen se puede obtener por introgresión de una planta cultivada a partir de semillas de las que se depositó una muestra representativa en la NCIMB con el número de registro 41857 en la NCIMB.
Patent ES-2042460-T1 (ES)
Title: Producto para el te\ido oxidativo del cabello y nuevo 5-halogeno-2,4-diamino-alquilbenzol.
Inventor: CLAUSEN THOMAS
IPC: C07C211/52
Filed: 1991-08-17
Abstract: LA INVENCION SE REFIERE A UN AGENTE PARA EL TINTE OXIDATIVO DEL CABELLO QUE CONTIENE AL MENOS UN COMPUESTO DE ACOPLAMIENTO DE LA FORMULA GENERAL (I) EN QUE R ES UN RESIDUO ALQUILO DE C SUB 1 A C SUB 4 DE CADENA RECTA O RAMIFICADA Y X ES FLUOR O BROMO, ASI COMO A NUEVOS 5-HALO-2, 4 -DIAMINOALQUILBENCENOS. LOS COMPUESTOS DE ACOPLAMIENTO DE LA FORMULA (I) SE PUEDEN PREPARAR MEDIANTE UNAS REACCIONES QUIMICAS SENCILLAS, SON FACILMENTE SOLUBLES EN AGUA Y SE PUEDEN ALMACENAR DURANTE LARGOS PERIODOS DE TIEMPO, EN PARTICULAR COMO UN COMPONENTE DEL AGENTE PARA EL TINTE DEL CABELLO DESCRITO. LOS AGENTES PARA EL TINTE DEL CABELLO PROPUESTOS NO SOLO PROPORCIONAN UNA AMPLIA GAMA DE SOMBRAS, SINO QUE ADEMAS, Y EN PARTICULAR, UNOS ROJOS INTENSOS Y UNOS AZULES MUY PUROS.
Patent CY-1106957-T1 (CY)
Title: Ν-σουλφονυλο-4-μεθυλεναμινο-3-υδροξυ-2-πυριδονες ως αντιμικροβιακοι παραγοντες
Inventor: WARSHAKOON NAMAL CHITHRANGA
IPC: A61K31/4412
Filed: 2007-10-25
Abstract: Οι ενώσεις του τύπου (Ι) είναι αποτελεσματικές στη θεραπεία μιας μικροβιακής λοίμωξης.
Patent CY-1110388-T1 (CY)
Title: Χρηση υποκατεστημενων παραγωγων κουινολινης για τη θεραπευτικη αντιμετωπιση μυκοβακτηριακων ασθενειων ανθεκτικων σε φαρμακα
Inventor: ANDRIES KOENRAAD JOZEF LODEWIJK MARCEL
IPC: A61P31/06
Filed: 2008-07-02
Abstract: Η παρούσα εφεύρεση αναφέρεται στη χρήση ενός υποκατεστημένου παραγώγου κουινολίνης για την παρασκευή ενός φαρμάκου για τη θεραπευτική αντιμετώπιση μίας μόλυνσης μ' ένα ανθεκτικό σε φάρμακα στέλεχος Mycobacterium όπου το υποκατεστημένο παράγωγο κουινολίνης είναι μία ένωση σύμφωνα με τον Τύπο (Ia) ή τον Τύπο (Ib) στα φαρμακευτικώς ανεκτά άλατα πρόσθεσης οξέος ή βάσης αυτών, στις στερεοχημικά ισομερείς μορφές αυτών, στις ταυτομερείς μορφές αυτών και στις μορφές N-οξειδίου αυτών. Επίσης αξιώνεται μία σύνθεση που περιλαμβάνει ένα φαρμακευτικώς ανεκτό φορέα και, ως ενεργό συστατικό, μία θεραπευτικώς δραστική ποσότητα των παραπάνω ενώσεων κι έναν ή περισσότερους άλλους αντιμυκοβακτηριακούς παράγοντες.
Patent CY-1108592-T1 (CY)
Title: Διϋδροτετραβεναζινες και φαρμακευτικες συνθεσεις που τις περιεχουν
Inventor: CLARKE IAN
IPC: A61P25/24
Filed: 2008-11-26
Abstract: Η εφεύρεση παρέχει πρωτότυπα ισομερή διϋδροτετραβεναζίνης, επιμέρους εναντιομερή και μείγματα αυτών όπου η διϋδροτετραβεναζίνη είναι 3,11b-cis-διϋδροτετραβεναζίνη. Επίσης παρέχονται μέθοδοι για την παρασκευή των πρωτότυπων ισομερών, φαρμακευτικές συνθέσεις που τα περιέχουν και η χρήση τους στην θεραπευτική αντιμετώπιση διαταραχών υπερκινητικότητας όπως της νόσου του Huntington, ημιβαλλισμού, γεροντικής χορείας, τικ, όψιμης δυσκινησίας, και του συνδρόμου Tourette.
Patent CY-1108905-T1 (CY)
Inventor: OP DEN CAMP HUBERTUS JOHANNES MARIE
IPC: C12P7/18
Filed: 2009-03-23
Abstract: The present invention relates to host cells transformed with a nucleic acid sequence encoding a eukaryotic xylose isomerase obtainable from an anaerobic fungus. When expressed, the sequence encoding the xylose isomerase confers to the host cell the ability to convert xylose to xylulose which may be further metabolized by the host cell. Thus, the host cell is capable of growth on xylose as carbon source. The host cell preferably is a eukaryotic microorganism such as a yeast or a filamentous fungus. The invention further relates to processes for the production of fermentation products such as ethanol, in which a host cell of the invention uses xylose for growth and for the production of the fermentation product. The invention further relates to nucleic acid sequences encoding eukaryotic xylose isomerases and xylulose kinases as obtainable from anaerobic fungi.
Patent CY-1109527-T1 (CY)
Inventor: GROMAN ERNEST V
IPC: A61K49/18
Filed: 2009-12-01
Abstract: Compositions, methods of making the compositions, and methods of using the compositions are provided for an enhanced magnetic resonance imaging agent and a hematinic agent, the agents comprising carboxyalkylated reduced polysaccharides coated ultrasmall superparamagnetic iron oxides. Methods of use of the carboxymethyl reduced dextran as a plasma extender are provided.
Patent CY-1111405-T1 (CY)
Title: Βενζαμιδιο και ετεροαρυλαμιδιο ως ανταγωνιστες υποδοχεα ρ2χ7
Inventor: DUPLANTIER ALLEN JACOB
IPC: C07D409/12
Filed: 2011-04-26
Abstract: Η παρούσα εφεύρεση σχετίζεται με νέους αναστολείς Ρ2Χ7 του τύπου (I) και με μεθόδους παρασκευής τους, με ενδιάμεσες ενώσεις χρήσιμες για την παρασκευή τους, με φαρμακευτικές συνθέσεις που τους περιέχουν, και με τη χρήση τους στη θεραπευτική. Οι δραστικές ενώσεις της παρούσας εφεύρεσης είναι ισχυροί αναστολείς του Ρ2Χ7 κι ως τέτοιες είναι χρήσιμες για τη θεραπεία της φλεγμονής, της οστεοαρθρίτιδας, της ρευματοειδούς αρθρίτιδας, του καρκίνου, της επαναιμάτωσης ή της ισχαιμίας στο εγκεφαλικό επεισόδιο ή την καρδιακή προσβολή, αυτοάνοσων ασθενειών κι άλλων διαταραχών.
Patent CY-1114109-T1 (CY)
Title: Διαταξη και μεθοδος για τη συνδεση σωληνων
Inventor: WHITE JOHN
IPC: E21B41/04
Filed: 2013-07-04
Abstract: Μία διάταξη (40) για τη σύνδεση γειτονικών άκρων ενός πρώτου (42) και ενός δεύτερου (44) σωλήνα περιλαμβάνει: - ένα σύνολο πλαισίου (46), το οποίο συμπεριλαμβάνει ένα σημείο συναρμολόγησης για τη συναρμολόγηση του άκρου του πρώτου σωλήνα (42) σε μία σταθερή θέση, - έναν οδηγό (48), ο οποίος συνδέεται με το σύνολο πλαισίου (46) και ο οποίος συμπεριλαμβάνει πρώτο (50) και δεύτερο (52) οδηγητήριο σχηματισμό για τη λήψη των οδηγητήριων βραχιόνων (60, 62), οι οποίοι είναι προσαρτημένοι στο άκρο του δεύτερου σωλήνα (44)· και - έναν κινητό φορέα (54) συναρμολογημένο επί του πλαισίου (46) και ο οποίος συμπεριλαμβάνει σχισμές για τη σύζευξη των οδηγητήριων βραχιόνων (60, 62). Ο φορέας (54) είναι κινητός μεταξύ μίας πρώτης θέσης, κατά την οποία οι σχισμές ευθυγραμμίζονται με τους οδηγητήριους σχηματισμούς (50, 52), έτσι ώστε οι οδηγητήριοι βραχίονες (60, 62) να είναι δυνατόν να διέλθουν εντός των σχισμών και μία δεύτερη θέση, κατά την οποία το άκρο του δεύτερου σωλήνα (44) συγκρατείται επί του άκρου του πρώτου σωλήνα (42), έτσι ώστε να επιτρέπεται να σχηματίζεται μία σύνδεση, ώστε να στερεωθούν ασφαλώς μεταξύ τους τα άκρα.
Patent CY-1114752-T1 (CY)
Title: Δεφερασιροξη για την αντιμετωπιση της κληρονομικης αιμοχρωματωσης
Inventor: NICK HANSPETER
IPC: A61P43/00
Filed: 2014-01-16
Abstract: Η παρούσα εφεύρεση αναφέρεται στη χρήση της Ένωσης I του ακόλουθου χημικού τύπου στην αντιμετώπιση της υπερφόρτωσης σιδήρου που οφείλεται στην κληρονομική αιμοχρωμάτωση σε ασθενείς που χρήζουν τέτοιας θεραπείας και σε ένα εμπορικό σκεύασμα που περιέχει την Ένωση I μαζί με οδηγίες για την αντιμετώπιση της υπερφόρτωσης σιδήρου στους ασθενείς με κληρονομική αιμοχρωμάτωση.
Patent CY-1116396-T1 (CY)
Title: Νεα συνθεση για τη θεραπευτικη αγωγη ιδιοπαθους θρομβοκυτταραιμιας
Inventor: WIDMANN RUDOLF
IPC: A61K31/517
Filed: 2015-05-29
Abstract: Η παρούσα εφεύρεση αφορά νέα φαρμακευτική σύνθεση απαλλαγμένη από γαστρική επικάλυψη η οποία περιέχει υδροχλωρική αναγρελίδη σε συνδυασμό με ένα μη εξαρτώμενο από το pΗ πολυμερές και φαρμακευτικώς αποδεκτό υδροδιαλυτό πολυμερές και τη χρήση αυτής για τη θεραπευτική αγωγή ιδιοπαθούς θρομβοκυτταραιμίας.
Patent CY-1116797-T1 (CY)
Title: Αναστολεις φωσφοϊνοσιτιδιου 3-κινασης με ενα τμημα δεσμευσης ψευδαργυρου
Inventor: CAI XIONG
IPC: C07D491/04
Filed: 2015-10-13
Abstract: Η τρέχουσα αίτηση αναφέρεται σε απαζαπουρίνες, θειενοπυριμιδίνες και φουροπυριμιδίνες με βασιζόμενα σε τμήμα δέσμευσης ψευδαργύρου παράγωγα και στη χρήση τους στη θεραπευτική αντιμετώπιση σχετιζόμενων με φωσφοϊνοσιτιδίου 3 κινάσης παθήσεων και διαταραχών, όπως του καρκίνου. Η τρέχουσα αίτηση αναφέρεται περαιτέρω στη θεραπευτική αντιμετώπιση σχετιζόμενων με ιστονική απακετυλάση διαταραχών και παθήσεων που σχετίζονται με αμφότερες την ιστονική απακετυλάση και τη φωσφοϊνοσιτιδίου 3 κινάση.
Patent CY-1117728-T1 (CY)
Title: Στερεες μορφες 3-(6-(1-(2,2-διφθοροβενζο[d][1,3]διοξολ-5-υλ) κυκλοπροπανοκαρβοξαμιδο)-3-μεθυλπυριδιν-2-υλ)βενζοϊκου οξεος
Inventor: KESHAVARZ-SHOKRI ALI
IPC: A61K9/28
Filed: 2016-07-05
Abstract: Η παρούσα εφεύρεση αφορά ουσιαστικά μία στερεά μορφή του 3-(6-(1-(2,2-διφθοροβενζο[d][1,3]διοξολ-5-υλ) κυκλοπροπανοκαρβοξάμιδο)-3-μεθυλπυριδιν-2-υλ)βενζοϊκού οξέος (Ενωση 1, διαλύτωμα Μορφή Α και Ένωση 1, HCI Άλας Μορφή Α), μεθόδους για κατασκευή τέτοιων μορφών, φαρμακευτικές συνθέσεις αυτών, και μεθόδους θεραπείας με αυτές.
Patent CY-1117960-T1 (CY)
Title: Φωσφοραμιδικα νουκλεοτιδια ως αντικαρκινικοι παραγοντες
Inventor: MCGUIGAN CHRISTOPHER
IPC: A61K31/7072
Filed: 2016-09-05
Abstract: Περιγράφονται φωσφοραμιδικά παράγωγα νουκλεοτιδίων και η χρήση τους στη θεραπεία του καρκίνου. Τα βασικά τμήματα των π.χ. δεοξυουριδίνης, κυταραβίνης, γεμσιταβίνης και σιτιδίνης μπορεί να φέρουν υποκατάστατες στην 5-θέση. Το φωσφοραμιδικά τμήμα έχει προσκολλημένο στο άτομο Ρ ένα αρυλο-O τμήμα και ένα τμήμα α-αμινοξέος. Το τμήμα α-αμινοξέος μπορεί να αντιστοιχεί ή να προέρχεται από ένα απαντώμενο ή μη στη φύση αμινοξύ.