baber/WOPTO huggingface dataset:
Patent AU-2021223893-A1 (AU)
Title: Calibration of a sensor
Inventor: BARWELL NICHOLAS PAUL
IPC: G01N21/85
Filed: 2021-02-16
Abstract: There is provided a method of calibrating a sensor comprising a luminescent compound having a luminescence that depends on the concentration of an analyte, and a detector configured to detect light emitted by the luminescent compound, the method comprising providing a component comprising the luminescent compound in a package that maintains exposure of the luminescent compound to the analyte at a known first concentration, assembling the component into the sensor and measuring a first value of a characteristic of the luminescence of the luminescent compound while exposed to the analyte at the first concentration, measuring a second value of the characteristic of the luminescence of the luminescent compound while exposed to the analyte at a known second concentration different from the first concentration, and determining parameters representing the dependence of the characteristic of the luminescence on concentration of the analyte using the first value and the second value.
Patent AU-2021228377-A1 (AU)
Title: Apparatus and method for collecting a breath sample using an air circulation system
Inventor: PURVES CHRISTOPHER QUENTIN
IPC: A61B5/08
Filed: 2021-01-28
Abstract: An apparatus and method for collecting a breath sample are provided. The apparatus has a breath input interface configured to receive exhaled breath, a first conduit system connected to the breath input interface, a valve configured to control fluid communication between the first conduit system and at least one breath sample storage device configured to store a breath sample, an air circulation system configured to circulate air through the first conduit system upon completion of a first received exhaled breath, and at least one controller configured to control the valve upon completion of the first received exhaled breath at least partially based on a humidity level in the first conduit system.
Patent AU-2021228763-A1 (AU)
Title: Activity based host cell protein profiling
Inventor: QIU HAIBO
IPC: G01N33/68
Filed: 2021-02-27
Abstract: The present application provides methods and systems for identifying host cell protein impurities which have enzymatic activities in biopharmaceutical products and in samples during manufacturing processes. The present application provides various activity-based probes to characterize different enzyme classes of host cell protein impurities including probes containing functionalized molecules with reporter or affinity-based tags.
Patent AU-2021229373-A1 (AU)
Title: Helical anchor foundation system
Inventor: RUSS KEVIN J
IPC: E02D37/00
Filed: 2021-02-22
Abstract: According to some embodiments, a light pole replacement system is disclosed. The light pole replacement system comprises a foundation plate to support a replacement light pole, a plurality of anchor tubes, threaded rods, and tension bolt adapters. The plurality of anchor tubes is placed into the ground based on a determined placement of the plurality of anchor tubes. Holes are created in the foundation plate based on a location of the plurality of anchor tubes and the foundation plate is placed over the plurality of anchor tubes with the threaded rods and the tension bolt adapters in the plurality of anchor tubes to couple the foundation plate to the plurality of anchor tubes.
Patent AU-2021240162-A1 (AU)
Title: EGFR inhibitor compounds
Inventor: BUNKER KEVIN DUANE
IPC: C07D403/14
Filed: 2021-09-29
Abstract: EGFR INHIBITOR COMPOUNDS 
ABSTRACT OF THE DISCLOSURE 
Disclosed herein are nitrogen-containing bicyclic compounds, together with 
pharmaceutical compositions and methods of ameliorating and/or treating a cancer described 
herein with one or more of the compounds described herein.  
18091812 1 (GHMatter) P109997.AU.1
Patent AU-2021246472-A1 (AU)
Title: Sterilization of self-assembling peptides by irradiation
Inventor: RIOULT MARIKA G
IPC: A61K38/00
Filed: 2021-03-30
Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self- assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
Patent AU-2021269332-A1 (AU)
Title: Connecting joint
Inventor: CAO HUIJIAN
IPC: F16L47/24
Filed: 2021-11-16
Abstract: The present disclosure relates to a connecting joint, including a connecting tube and a first 
compression sleeve. The connecting tube includes a first tube connecting section for connecting 
a first tube and a second tube connecting section for connecting a second tube. The first tube 
connecting section and the second tube connecting section are communicated and an annular 
connecting plate is arranged therebetween. The first compression sleeve is sleeved on the second 
tube connecting section. A first insertion hole with an annular cross-section for the second tube 
to be inserted into is formed between an inner wall of the first compression sleeve and an outer 
wall of the second tube connecting section. A first annular groove is formed in an outer surface 
of one end of the second tube connecting section close to the annular connecting plate. An end 
portion of one end of the first compression sleeve close to the annular connecting plate is bent 
toward the second tube connecting section and inserted into the first annular groove. The 
connecting joint provided by the present disclosure can simplify the connection of the connecting 
joint and the plastic tube and save installation time and is convenient to install.
Patent AU-2021277618-A1 (AU)
Title: Ergonomically designed vaginal speculum
Inventor: NAIGAMWALLA DARIUS
IPC: A61B1/32
Filed: 2021-11-30
Abstract: he present disclosure relates to an ergonomically designed vaginal speculum. The 
peculum includes a body portion comprising a handle configured to be grasped by a 
iser of the speculum, a lower bill, and a transition portion between the handle and the 
power bill. The speculum further includes an upper bill rotatably coupled to the lower 
ill at the transition portion, allowing the upper bill to move relative to the lower bill to 
nove the speculum into an open position, a window frame coupled to the upper bill 
defining a viewing window, and an actuation mechanism coupled to the upper bill to 
:ause separation of the upper bill from the lower bill. The transition portion creates an 
ingle greater than 90 degrees between the handle and the lower bill. The speculum 
nay further include a locking mechanism and an illumination source.
Patent AU-2021282817-A1 (AU)
Title: Bispecific antibody or antigen-binding fragment thereof, and preparation method therefor
Inventor: JUNG SUNG YOUB
IPC: A61P25/28
Filed: 2021-05-28
Abstract: The present invention provides: a protein complex having a high heterodimer formation rate; a preparation method therefor; a pharmaceutical composition for preventing or treating cancer, containing the protein complex; and a method for preventing or treating cancer by using the composition. According to the present invention, a bispecific antibody or an antigen-binding fragment having improved stability, a receptor and a receptor-binding agonist, antagonist, ligand, cytokine, or receptor decoy biconjugate can be easily prepared and used in various fields such as that of disease prevention or treatment and disease diagnosis.
Patent AU-2021292231-A1 (AU)
Title: CD38 antibodies for the treatment of human diseases
Inventor: MAHIUDDIN AHMED
IPC: C07K16/28
Filed: 2021-06-14
Abstract: The present invention relates to antibodies and antigen binding fragment thereof, capable of binding to CD38 antigen. More specifically, the invention relates to antibodies and antigen binding fragments, wherein said antibodies or antigen binding fragments comprises sequences of human origin, and wherein said sequences of human origin reduces immunogenicity compared to a murine antibody. The invention further relates to bispecific antibodies for binding to CD38 and CD3. Further, the invention relates to bispecific antibodies for binding to CD38 and a chelator. The invention further relates to antibodies and antigen binding fragments for the treatment of cancer and autoimmune diseases.
Patent AU-2021305175-A1 (AU)
Title: Multifunctional cement additives and methods of using same
Inventor: AN JUN SU
IPC: C04B24/32
Filed: 2021-07-07
Abstract: A multifunctional cement additive comprising a biochelant; and a solvent; wherein the biochelant comprises a sodium glucarate liquid oxidation product comprising predominantly gluconate and glucarate anions with minor component species of n-keto-acids and C
Patent AU-2021372512-A1 (AU)
Title: Regimens for the treatment of hair loss disorders with deuterated jak inhibitors
Inventor: CASSELLA JAMES
IPC: A61K31/519
Filed: 2021-10-28
Abstract: Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an effective amount of Compound (I): or a pharmaceutically acceptable salt thereof.
Patent AU-2021376310-A1 (AU)
Title: Oral rinse, nasal spray and methods for prevention of covid-19 by lowering viral load of covid-19
Inventor: CRAWFORD KEITH
IPC: A61K31/79
Filed: 2021-11-09
Abstract: Compositions and methods are provided for a nasal spray or mouthwash formulation for prevention and amelioration of disease progression caused by a virus infection, the formulation including: an algae derivative; and a buffer. The method effectively bathes the mouth and throat tissues to decrease COVID-19 concentration and functionality; thereby preventing growth and spread of the virus and lower the viral load present in the lungs and in GI tract.
Patent AU-2021378583-A1 (AU)
Title: Modular augment
Inventor: In yong
IPC: A61F2/30
Filed: 2021-08-27
Abstract: The present invention relates to a modular augment and, more specifically, to a modular augment having an additional unit separably coupled to a center unit, so as to selectively couple the additional unit to the center unit according to the degree of bone loss of a patient, and thus can easily adjust the degree of bone reinforcement, so that costs required for manufacturing can be reduced since a manufacturer can provide an augment capable of covering various types of patients even though the types of units are minimized, the number of products to be prepared for surgery by a user at hospitals and the like are remarkably reduced to prevent unnecessary cost consumption and facilitate stock management, and an optimal augment that is appropriate for the condition of a patient can be provided to the patient.
Patent AU-2021393068-A1 (AU)
Title: Evaporator for a refrigeration installation delimiting two evaporation chambers, one at high pressure and one at low pressure, these being separated by a filtration screen
Inventor: CHARBONNEAU THOMAS
IPC: F25B39/02
Filed: 2021-12-01
Abstract: What is described as an evaporator (10) for a refrigeration installation (100) comprising a high-pressure chamber (14), a low-pressure chamber (17), a filtration screen (24) interposed between the high-pressure chamber (14) and the low-pressure chamber (17) and a communication duct (25) connecting the high-pressure chamber (14) to the low-pressure chamber (17). The filtration screen (24) allows the working fluid in the gaseous phase (15) to pass from the high-pressure chamber (14) to the low-pressure chamber (17) and blocks the passage of the working fluid in the liquid phase (16, 19) from the high-pressure chamber (14) to the low-pressure chamber (17) and vice versa. The communication duct (25) essentially allows the working fluid in the liquid phase (16) to pass from the high-pressure chamber (14) to the low-pressure chamber (17) and opposes the free passage of the working fluid in the gaseous phase (15, 18) from the high-pressure chamber (14) to the low-pressure chamber (17) and vice versa.
Patent AU-2021398814-A1 (AU)
Title: Novel intermediate, preparation method for same, and applications thereof
Inventor: QIN YONG
IPC: C07D489/08
Filed: 2021-10-13
Abstract: The invention relates to the field of medicament synthesis and specifically to a novel intermediate, a preparation method for same, and applications thereof. The structural formula of the novel intermediate of the present application is as represented by formula (I): in which R is a secondary amine protecting group. The present invention, based on possible biogenetic pathways of morphine derivatives, by means of a strategy for biomimetic synthesis, with an asymmetric transfer hydrogenation reaction and an intramolecular oxidative dearomatization Heck reaction in the preparation process of the intermediate serving as key reactions for total synthesis, implements the highly efficient synthesis of the morphine derivatives. The synthesis of the morphine derivatives starting from the novel intermediate provided in the present invention is characterized by significantly reduced synthesis steps, an increased yield, a reduced discharge of gaseous, liquid, and solid wastes, and inexpensive production costs.
Patent AU-2021401310-A1 (AU)
Title: Systems and methods for automatic extraction of classification training data
Inventor: MAZOR IGAL
IPC: G06F40/30
Filed: 2021-12-17
Abstract: A method for training a multi-class classification model includes receiving training data corresponding to a plurality of classes. For each class in the plurality of classes, the method includes training a binary classification model configured to determine whether or not an observation of training data belongs to the class and for each observation of training data identified as belonging to the class, extracting one or more class identification features from the observation of training data based on activations of an intermediate attention layer in the binary classification model. A multi-class classification model is trained using the class identification features extracted for each of the plurality of classes.
Patent AU-2021410771-A1 (AU)
Title: Catheter housing
Inventor: ALBANY RAMY
IPC: A61M25/02
Filed: 2021-12-22
Abstract: A catheter housing device comprising a hub configured for placement at a catheter insertion site on a subject and a cover configured to secure to the hub to enclose the catheter insertion site. In some implementations, the hub includes: a membrane having an opening positioned over the catheter insertion site when the membrane is secured to the subject's skin, a frame connected to the membrane along a perimeter of the opening; and a pair of arms extending from the frame partially across the opening towards one another and configured to secure a catheter hub connected to a catheter to minimize movement of the catheter when inserted in the catheter insertion site.
Patent AU-2021451465-A1 (AU)
Title: Household appliance with improved firmware update
Inventor: FABRICI LUCIO
IPC: G06F8/65
Filed: 2021-06-14
Abstract: A household appliance (100) is proposed. The household appliance (100) comprises a plurality of processing units (PU
Patent WO-2022160015-A1 (WO)
Inventor: VON ITZSTEIN MARK
IPC: A61P31/16
Filed: 2022-01-28
Abstract: La présente invention concerne un composé de formule (I), ou un sel pharmaceutiquement acceptable de celui-ci, et des compositions pharmaceutiques comprenant le composé. Dans la formule (I), les cycles W, X, Y et Z peuvent se rapporter à divers cycles hétérocycliques, hétéroaryle, cycloalkyle, cycloalcényle et/ou aryle. La présente invention concerne également des utilisations des composés dans le traitement d'une maladie, d'un trouble ou d'un état provoqué par une infection virale. (I), R3 est choisi dans le groupe constitué de :
Patent AU-2022204062-A1 (AU)
Title: Implantable scaffolds for treatment of sinusitis
Inventor: YOU CHANGCHENG
IPC: A61F2/82
Filed: 2022-06-10
Abstract: IMPLANTABLE SCAFFOLDS FOR TREATMENT OF SINUSITIS 
ABSTRACT 
This disclosure describes, inter alia, materials, devices, kits and methods that may be 
used to treat chronic sinusitis. An implant X" is configured to fit inside of the middle meatus of 
a human nasal cavity. The implant includes a therapeutic-agent formulation containing a layer of 
over 2000 micrograms of mometasone furoate. The implant releases the mometasone furoate for 
more than 12 weeks. A second implant can also be provided configured to fit inside the middle 
meatus. The second implant also includes a therapeutic-agent formulation containing a layer of 
over 2000 micrograms of mometasone furoate, and releases the mometasone furoate for more 
than 12 weeks.
Patent AU-2022217900-A1 (AU)
Title: Modulating energy usage based on a current tariff in a water provision system
Inventor: KONOWALCZYK PETER
IPC: F24D19/10
Filed: 2022-02-07
Abstract: A heater arrangement system for a water provision system for controlling a water supply provided to a water outlet, the water outlet being arranged to provide heated water to a user, the heater arrangement system comprising: a water heating device disposed remotely from the water outlet; and a control unit communicatively coupled to the water heating device, the control unit being configured to: receive a request from a user to enable a reduced temperature water supply mode, which provides for heated water to be supplied to the water outlet at a first temperature for a fixed period of time and then provides for the temperature to be lowered to a second temperature once the fixed time has elapsed; and for a user for which the request has been received, upon detecting that the user has opened the water outlet, providing heated water at the first temperature for a first period of time, then reducing the temperature of the heated water from the first temperature to a second temperature lower than the first temperature after the first period of time has elapsed.
Patent AU-2022227021-A1 (AU)
Title: Lymphocyte targeted lentiviral vectors
Inventor: PERKINS MOLLY R
IPC: C07K14/145
Filed: 2022-02-25
Abstract: Provided herein are lentiviral vectors comprising a mutated, heterologous envelope protein, a targeting protein, and at least one transgene for delivery to and expression by a cell characterized by the targeting protein. Also provided are methods and materials for producing the lentiviral vectors described herein, methods for transducing target cells, and cells transduced by lentiviral vectors according to the present disclosure.
Patent AU-2022227771-A1 (AU)
Title: Strategies to develop genome editing spherical nucleic acids (snas)
Inventor: MIRKIN CHAD A
IPC: A61K9/127
Filed: 2022-02-25
Abstract: Spherical nucleic acids (SNAs) are an attractive platform for therapeutic delivery due to their chemically tunable structures, biocompatibility, and ability to rapidly enter cells without transfection reagents. The present disclosure provides SNAs and strategies for delivering gene editing proteins into cells. The delivered gene editing proteins remain enzymatically active and rapidly enter mammalian cells.
Patent AU-2022231761-A1 (AU)
Title: Mycoplasma bovis compositions
Inventor: BROWNING GLENN FRANCIS
IPC: A01H1/06
Filed: 2022-09-15
Abstract: Document3-15/09/2022 
Mycoplasma bovis compositions 
ABSTRACT 
5 Disclosed herein are Mycoplasma bovis immunogenic compositions useful in raising 
an immune response in animals against M. bovis. Also disclosed herein are methods for 
generating a protective response against infections in mammals caused by M. bovis.  
9M0 
8.50 _____ 
8.00 
7>50 33C 
U 38C 
7.00 
6.50 
6.00 
3683 wt 3683 Ts N2805-1 
FIG. 1
Patent AU-2022239333-A1 (AU)
Title: Bifunctional molecules for treatment of immune disorders
Inventor: TSURUSHITA NAOYA
IPC: C07K16/28
Filed: 2022-03-14
Abstract: The invention provides bifunctional molecules including an antibody specifically binding to CD122 and an extracellular domain of CTLA-4. The bifunctional molecules specifically bind to CD122 and CTLA-4 ligands, CD80 and CD86 and inhibit their function in immune activation. The bifunctional molecules can inhibit interaction of CD122 with its ligands IL-2 and IL-15 and inhibit interaction of CD80 and CD86 with their counter-receptor, CD28. These bifunctional molecules can suppress Signals 2 and 3 of immune responses as a single therapeutic agent for treatment of immune disorders.
Patent AU-2022242806-A1 (AU)
Title: Laparoscopic anastomosis devices and methods of use thereof
Inventor: SHARMA TUSHAR
IPC: A61B17/11
Filed: 2022-03-22
Abstract: An apparatus includes an interface, and an elongate body coupled to the interface. An end effector is coupled to a distal end the elongate body and includes a first end effector element defining a first receptacle structured to hold a first coupler element of a coupler that receives an axial end of a first vessel, and a second end effector element defining a second receptacle structured to hold a second coupler element of the coupler that receives an axial end of a second vessel. The end effector is configured to move between a first configuration in which the first and second end effector elements are separate, and a second configuration in which first end effector element is proximate to the second end effector element such that the first coupler element is coupled to the second coupler element so as to couple the first vessel to the second vessel.
Patent AU-2022263527-A1 (AU)
Title: System and method for decision support using lifestyle factors
Inventor: DAVIS ANNA LEIGH
IPC: G16H20/30
Filed: 2022-11-03
Abstract: Systems and methods are provided relating to open loop decision-making for 
management of diabetes. People with diabetes face many problems in controlling their glucose 
because of the complex interactions between food, insulin, exercise, stress, activity, and other 
physiological and environmental conditions. Established principles of management of glucose 
sometimes are not adequate because there is a significant amount of variability in how different 
conditions impact different individuals and what actions might be effective for them.  
Accordingly, systems and methods according to present principles minimize the impact of the 
vagaries of diabetes on individuals, i.e., by looking for patterns and tendencies of an individual 
and customizing the management to that individual. Consequently, the same reduces the 
uncertainty that diabetes typically is associated with and improves quality of life.
Patent AU-2022266591-A1 (AU)
Title: Devices and methods for joint repair
Inventor: HOSSEINI ALI
IPC: A61B17/04
Filed: 2022-04-26
Abstract: Methods and devices for tissue fixation. A cortical button with a rib between two slotted openings. The rib increases the cortical button structural rigidity without increasing palpability. An adjustable loop construct with two discrete locking passages that provides manageable loop reduction and improved tissue coupling. The adjustable loop construct may be coupled to tissue via a passing construct. An assembly with a reduction bar, a button and an adjustable loop construct, the assembly provided assembled in a first configuration that disassembles to guide steps of tissue fixation. The reduction bar may be assembled to the reduction bar for reducing the adjustable loop construct.
Patent AU-2022275666-A1 (AU)
Title: Il-21 polypeptides and targeted constructs
Inventor: YEUNG YIK ANDY
IPC: A61K38/20
Filed: 2022-04-27
Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.