baber/WOPTO huggingface dataset:
Patent NZ-507717-A (NZ)
Title: Derivatives of pneumococcal choline binding proteins for vaccines
Inventor: WIZEMANN THERESA M
IPC: A61K39/40
Filed: 1999-04-06
Abstract: A vaccine for treating or protecting against pneumococcal infection comprises a polypeptide in a pharmaceutically acceptable carrier. The polypeptide comprises an alpha helical portion having at least 95% identity to the sequence of SEQ ID NO:1 and does not contain a choline-binding portion. Also described is an antibody raised against the polypeptide when the polypeptide does not comprise an HPS portion. The vaccine or antibody can be used in the manufacture of a medicament for treating or preventing pneumococcal infection. Preferably the an otitis media infection caused by Streptococcus pneumoniae.
Patent NZ-511217-A (NZ)
Title: Method for measuring cellular adhesion
Inventor: DOPHEIDE SACHA MARIE
IPC: G01N33/543
Filed: 1999-10-20
Abstract: A diagnostic method for determining the binding capacity of cells such as platelets or progenitors thereof in a biological sample comprises passing the biological sample over an adhesive substrate immobilised on a solid support under defined flow conditions and for a time sufficient to enable cells from the biological sample to bind to the adhesive substrate, and subsequently detecting cells bound to the adhesive substrate. The method may be used for detection in an individual of the presence of or risk of developing a condition or disorder involving cellular, particularly platelet, abnormalities.
Patent NZ-514200-A (NZ)
Title: A device for cutting adhesive labels from the release liner and fed into two separate offset roller assemblies
Inventor: WESTRAY JOHN ALAN
IPC: B65C9/18
Filed: 2001-09-17
Abstract: Curved and irregularly shaped self-adhesive labels are firstly set onto a master roll in an interlocking pattern. This master roll is fed into a finishing apparatus that includes at least one die cutter (1) and at least two offset roller assemblies (2,3). The master roll is fed into the die cutter which functions to cut the release liner to form two separate symmetrical curved shaped feeds. It is this arrangement that allows for minimum material wastage.
Patent NZ-519403-A (NZ)
Title: Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
Inventor: LANDSCHULZ WILLIAM HARRAS
IPC: A61K9/12
Filed: 2002-06-06
Abstract: Inhaled insulin, relative to subcutaneously and/or transdermally administered, can be used to prevent the rate of weight gain and to lower the levels of fasting glucose in diabetic patients.
Patent NZ-523249-A (NZ)
Title: Method of delivering compositions to substrates
Inventor: MAYNARD NIGEL PAUL
IPC: B05D7/06
Filed: 2002-12-16
Abstract: A method of delivering a composition such as biocidal compositions to a substrate such as lumber, the method comprising at least the steps of: a. heating a target zone of a substrate; and b. applying a composition to a surface of the substrate comprising or immediately adjacent to the target zone; wherein the composition is at a temperature below that of the target zone of the substrate.
Patent NZ-531730-A (NZ)
Title: Method for controlling electronic parcel compartment systems and an interface for carrying out said method
Inventor: MAYER BORIS
IPC: A47G29/14
Filed: 2002-10-07
Abstract: A method for controlling electronic parcel package compartment systems characterised in that: (a) A checking procedure is carried out in the area of the server to see whether changes have been made to the data stored in the server; and, (b) Control commands are transmitted via an interface to the parcel compartment system as soon as a pre-definable number of changes have been made to the data stock.
Patent NZ-536645-A (NZ)
Title: Application of loading ledges
Inventor: DICKNER ALLAN
IPC: B65B13/18
Filed: 2003-04-22
Abstract: A system (10, 100, 110) for applying loading ledges (20) onto a unit load (30) positioned on supporting means (81, 82, 83, 84). The system comprises an application machine (10). The system also comprises means for separating the unit load from the supporting means in the vertical direction. The system also comprises means (50, 51, 52, 130, 140) for applying at least one loading ledge to at least two opposite, lower edges of the unit load when separated from the supporting means.
Patent NZ-550364-A (NZ)
Title: Respirator with an outer mask and an inner oronasal mask, each with a one-way valve and filter
Inventor: SUTTON ROBERT CHARLES
IPC: A62B18/02
Filed: 2005-03-17
Abstract: A respirator comprising an outer mask (2) in which is defined a main volume (16) and an oronasal mask (4) located within the outer mask and defining a secondary volume (17). Air for breathing enters the mask (2) via a one-way valve (9) and filter (10). Exhaled air exits the mask (4) via an exhale conduit (5) fitted with an exhale valve (6). A conduit (11) is provided for the passage of air from the outer mask (2) to the oronasal mask (4). The conduit (11) is fitted with a one-way valve (12) and a filter (13). The filter (13) is such as to filter either particular or vapour challenges, or a mixture of these, as required.
Patent NZ-556641-A (NZ)
Title: Trailer mounted attenuator with breakaway axle assembly
Inventor: REID JOHN D
IPC: B60G9/00
Filed: 2006-01-10
Abstract: A crash attenuation system is disclosed. The crash attenuation system includes an impact head assembly connected to one end of a trailer frame member which has a hitch assembly at an opposing, and a breakaway axle assembly mounted to the frame member by fasteners. The trailer frame member includes a first frame rail assembly generally parallel to and spaced apart from a second frame rail assembly, where the first and second frame rail assemblies are connected to one another at the second end of the frame member by the hitch assembly. The breakaway axle assembly further connects the first and second frame rail assemblies when the impact head assembly is in a non-impacted position, and the fasteners release the breakaway axle assembly from the frame member when the impact head assembly is in an impacted position.
Patent NZ-563864-A (NZ)
Title: Vibration device
Inventor: HUGHES COLIN JONATHAN
IPC: H02K7/06
Filed: 2006-05-05
Abstract: A vibration device is disclosed. The device includes a motor having a stator (20, 30) and a rotor (80, 90), each having one or more magnetic elements. A magnetic element on at least one of the rotor and the stator comprises an electromagnet which can be supplied with an electric current so as to interact with a magnetic element on the other of the rotor and the stator to cause rotation of the rotor with respect to the stator. The one or more magnetic elements of the rotor, considered together, have a centre of mass (100) which is offset from the axis of rotation (40) of the rotor. The rotor and the stator are arranged within or together form, a cavity containing a liquid.
Patent NZ-567433-A (NZ)
Title: Dihydrogen phosphate salt of a prostaglandin d2 receptor antagonist
Inventor: LANGEVIN BEVERLY
IPC: A61K31/505
Filed: 2006-10-12
Abstract: Disclosed is a compound of Formula (III), and its use for treating an allergic disease, systemic mastocytosis, a disorder accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, bronchitis, urticaria, eczema, a disease accompanied by itch, a disease which is generated secondarily as a result of behavior accompanied by itch, inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, or ulcerative colitis.
Patent NZ-570564-A (NZ)
Title: Method of increasing the useful life of a sign or display
Inventor: HAYES RICHARD ALLEN
IPC: G09F1/12
Filed: 2007-03-19
Abstract: A method of increasing the useful life of a sign or other display is disclosed. A sign is displayed. The sign comprises: a first image on view, an intervening opaque layer, and a second image protected by the intervening opaque layer and by an opaque backing or structure. The first image on view is adhered to a first side of the intervening opaque layer. A second side of the intervening opaque layer is adhered to the second image. The second image is adjacent to the opaque backing or structure. This allows environmental degradation of the first image until one or more of the aesthetic characteristics of the first image are unacceptable. When this occurs, the sign or other display is reversed so that the second image is on view and the first image is protected by the intervening opaque layer and the opaque backing or structure. The reversed sign is then displayed.
Patent NZ-571294-A (NZ)
Title: Aeration duct for de-watering of slurries
Inventor: HODGES MICHAEL KENT
IPC: B01D29/05
Filed: 2007-02-16
Abstract: A duct for use in a slurry dewatering apparatus includes an inlet portion 20 for receiving a flow of water with suspended solids (slurry), and which has an inlet flow direction and a maximum inlet width a in the direction normal to the flow direction, and an outlet portion 26 having an outlet flow direction and a maximum outlet width A in a direction normal to the outlet flow direction that is greater than the inlet maximum width. A duct section 19 connects the inlet and outlet portions and a gas feed 34 is provided within the inlet portion or the duct section for allowing gas to be fed into the flow of slurry.
Patent NZ-571622-A (NZ)
Title: Rigid u-shaped packaging container with integral handle
Inventor: O'HARA JEFFREY
IPC: B65D61/00
Filed: 2007-02-23
Abstract: Disclosed is a packaging container (10) which has an integral handle (12). The container is formed from a preformed, rigid unit of generally U-shaped cross-section having a main body portion with a generally flat bottom wall and upstanding, opposing sidewalls. The unit is foldable at at least two regions to form a base channel (32) and opposing side channels (34) of a protective package for an item. Hand openings (24) are formed in the bottom wall of the opposing side channels configured for a user to insert a hand for use as the handle for the packaging container.
Patent NZ-572358-A (NZ)
Title: Lactate and calcium containing pharmaceutical composition and uses thereof
Inventor: LEVERVE XAVIER M
IPC: A61K31/19
Filed: 2006-04-03
Abstract: Disclosed is a pharmaceutical composition containing 500 to 1500 millimoles per liter of lactic acid or lactate, 1.2 to 1.7 millimoles per liter of calcium, and 2.5 to 6 millimoles per liter potassium. Also disclosed is the use of said composition for treating or preventing diseases or conditions selected from the group consisting of hypovolemia, operative treatment of patients, post-operative treatments of patients, cardiovascular diseases, brain disorders, organ failure, obesity, resuscitation, edema and acute hemodynamic distress due to medical treatment and surgery.
Patent NZ-576949-A (NZ)
Title: Prognostic method for determing liver functionality using bile acid derivatives and the MRP2 and MRP3 efflux pathway
Inventor: GRUSS HANS-JURGEN
IPC: C12Q1/25
Filed: 2009-05-13
Abstract: A method for determining liver function in a subject by determining the functional activity of the hepatocyte transport proteins MRP2 (Multidrug Resistance Protein 2) also known as ABCC2, MRP3 (Multidrug resistance Protein 2) also known as ABCC3 or OATP1B3 (organic anion transporting polypeptide) also known as SLCO1B3. The method comprises determining the level of a fluorescent bile acid derivative with the general formula (I) in a sample of blood taken from a subject after a predetermined time. The fluorescent bile acid derivative can be cholyl-lysyl-fluorescein (CLF).
Patent NZ-577991-A (NZ)
Title: Novel therapeutic use for treating myeloid leukaemia
Inventor: BOURRIE BERNARD
IPC: A61K31/433
Filed: 2007-12-27
Abstract: Disclosed herein is the use of N-[2-(2,1,3-benzothiadiazol-5-ylkamino)-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea for preparation of a drug for treating myeloid leukaemia wherein the form of administration is selected from intravenous or oral routes.
Patent NZ-579858-A (NZ)
Title: Macro-control of treatment for sleep disordered breathing
Inventor: BERTHON-JONES MICHAEL
IPC: A61B5/08
Filed: 2004-11-25
Abstract: An apparatus for evaluating changes in heart failure disease in a patient comprises a blower to provide a supply of pressurized breathable gas; a patient interface to deliver the pressurized gas from the blower to the patient; a flow sensor configured to measure an airflow of the patient; a controller for (a) determining one or more occurrences of central apnea based on the measured airflow; (b) calculating a heart failure index from a count of the number of central apneas that have occurred; and (c) comparing the calculated heart failure index to a previously calculated heart failure index to determine how the patient's heart failure disease has changed; and a means to provide an alert for any changes in disease progression.
Patent NZ-583181-A (NZ)
Title: Slide hammer comprising a shaft, plug and a tool portion
Inventor: IRVIN TIMOTHY JAMES
IPC: B25G3/04
Filed: 2011-02-08
Abstract: Disclosed is an implement (1) typically used for digging through tough materials such as hardened clay, stony or root laden grounds. The implement (1) comprises a shaft (2), a plug (13) and a tool portion (5). The shaft (2) includes a hollow receiving portion (3) in at least one end. A first portion of the plug (13) is frictionally engaged to the hollow receiving portion (23) of the shaft (2). The tool portion (5) includes a slot (23). The slot (23) is configured to allow the tool portion (5) to be attached to a second portion (21) of the plug (13) and at least the portion of the outer periphery of the shaft (2).
Patent NZ-588596-A (NZ)
Title: A container closure with an inverted peripheral skirt that fits over the container rim, while a distal end of the skirt will engage a wall formation within the container
Inventor: WOINARSKI DAVID ALEXANDER
IPC: B65D43/06
Filed: 2006-03-31
Abstract: A closure 10 for a container 12 that comprises a base 13 and peripheral wall 15, with a rim 16 forming an upper margin of the wall 15 and surrounding an opening of the container 12. The closure 10 comprises a wall 19 that is adapted to extend across and to overlie the container opening when the closure 10 is mounted to the container 12, the wall 19 extending inwardly from an inside wall 20 of an inverted peripheral channel section 22 of the closure 10 that is adapted to mount to the container rim 16. A peripheral skirt 24 projects at an obtuse angle from the closure wall 19 at or adjacent to its junction with the channel section 22 such that a distal end 28 of the skirt 24 can engage a wall formation 30 within the container 12 when the closure 10 is mounted on the container 12.
Patent NZ-589626-A (NZ)
Title: Wave energy conversion device comprising an s-shaped diaphragm
Inventor: TURNER DONALD MILNE
IPC: F03B13/14
Filed: 2009-05-13
Abstract: 589626 Disclosed is a water wave energy conversion device for generating electricity. The device includes a diaphragm supported by a frame, the frame and diaphragm together defining a cell for fluid. A duct extends from the cell; and a power-take-off device is associated with the duct and arranged to respond to fluctuation of the fluid in the cell and/or duct. The diaphragm is capable of changing shape in response to a change in pressure difference across the diaphragm, the change of shape causing a consequent change in the fluid in the cell, and hence a response in the power-take-off device. At least one edge of the diaphragm being attached to the frame in a S-shaped configuration. At least part of the diaphragm is one edge of the diaphragm, and an opposite edge of the diaphragm is also attached to the support structure along a second line of attachment, which second line of attachment is S-shaped.
Patent NZ-593511-A (NZ)
Title: Peritoneal dialysis methods and apparatus
Inventor: ROBERTS MARTIN
IPC: A61M1/00
Filed: 2007-01-30
Abstract: Disclosed is an ex-vivo method for producing a processed protein rich stream comprising: separating a blood-free fluid stream derived from a peritoneal cavity into a protein-rich stream and an ultrafiltrate, and processing at least some of the protein-rich stream to produce a processed protein rich stream, which includes the use of a sorbent system having an enzyme that is immobilized on a substrate with greater than Van der Waals forces wherein the sorbent removes at least one toxin from at least some of the protein-rich stream; wherein the processed protein rich stream is suitable for introduction into the peritoneal cavity; and wherein at least 80% of the substantially blood-free stream is suitable for introduction into the peritoneal cavity as a processed protein rich stream over a period of 8 hours. The method is useful as part of a peritoneal dialysis system.
Patent NZ-599204-A (NZ)
Title: High affinity human antibodies to human protease-activated receptor-2
Inventor: MACDONALD LYNN
IPC: A61P29/00
Filed: 2010-09-08
Abstract: 599204 Disclosed is an isolated human antibody or antigen-binding fragment thereof that specifically binds to human PAR-2 (SEQ ID NO:851), wherein the antibody or antigen-binding fragment thereof: (a) interacts with Ser-37, Leu-38, Ile-39, Gly-40, Val-42 and Asp-43 of human PAR-2; (b) does not interact with Lys-41 of human PAR-2; (c) blocks trypsin cleavage of human PAR-2 at the activating cleavage site located at the junction of residues Arg-36 and Ser-37 of human PAR-2; (d) does not block trypsin cleavage of human PAR-2 at the non-activating cleavage site located at the junction of residues Arg-31 and Ser-32; and (e) competes for binding to human PAR-2 with a reference antibody comprising heavy chain complimentary determining regions (HCDR1-HCDR2-HCDR3) having the amino acid sequences of SEQ ID NOs:700-702-704; and the light chain CDRs (LCDR1-LCDR2-LCDR3) having the amino acid sequences of SEQ ID NOs:708-710-712.
Patent NZ-599595-A (NZ)
Title: Condensed ring pyridine compounds as subtype-selective modulators of sphingosine-1-phosphate-2 (s1p2) receptors
Inventor: CHOW KEN
IPC: A61K31/136
Filed: 2010-09-28
Abstract: 599595 The disclosure provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds. Compounds disclosed include: N-(3,5-dichlorophenyl)-2-(4-methyl-1,8-naphthyridin-2-yl)hydrazine carboxamide; N-(3,5-dichlorophenyl)-2-(4-isopropyl-1,8-naphthyridin-2-yl)hydrazine carboxamide; N-(3,5-dichlorophenyl)-2-(4-isopropyl-5,8-dimethylquinolin-2-yl)hydrazinecarboxamide; N-(3,5-dichlorophenyl)-2-(4-isopropylquinolin-2-yl)hydrazinecarboxamide; N-(2,6-dichloropyridin-4-yl)-2-(4,8-dimethylquinolin-2-yl)hydrazine carboxamide; N-(3,5-dichlorophenyl)-2-(4,8-dimethylquinolin-2-yl)hydrazinecarboxamide; N-(2,6-dichloropyridin-4-yl)-2-(4-methylquinolin-2-yl)hydrazinecarboxamide; and N-(3,5-dichlorophenyl)-2-(4,5,8-trimethylquinolin-2-yl)hydrazinecarboxamide.
Patent NZ-600974-A (NZ)
Title: Binding members for human cytomegalovirus
Inventor: WINKLER THOMAS
IPC: A61K39/395
Filed: 2010-12-22
Abstract: Disclosed are antibodies that bind to a region of human cytomegalovirus (hCMV) gB protein at a region within residues 121 to 130 and 344 to 438. Also disclosed are compositions comprising of the disclosed antibodies and use of the disclosed antibodies in the manufacture of a medicament for treating a disorder associated with hCMV.
Patent NZ-603780-A (NZ)
Title: Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
Inventor: SCHERER STEFAN
IPC: G01N33/574
Filed: 2011-07-18
Abstract: Disclosed is an in vitro method for the identification of a patient responsive to or sensitive to the addition of bevacizumab treatment to a chemotherapy regimen, said method comprising determining the protein expression level of VEGFA and/or VEGFR2 in a sample from a patient suspected to suffer from or being prone to suffer from breast cancer, whereby an increased expression level of VEGFA and/or VEGFR2 relative to control expression levels determined in patients suffering from breast cancer is indicative of a sensitivity of the patient to the addition of bevacizumab to said chemotherapy regimen. Also disclosed is the use of bevacizumab for the preparation of a medicament for improving the progression free survival effect of a chemotherapy regimen of a patient suffering from breast cancer, wherein the protein expression level of VEGFA and/or VEGFR2 has been determined in a sample from said patient, and wherein the patient has an increased expression level of VEGFA and/or VEGFR2 relative to control expression levels determined in patients diagnosed with breast cancer, wherein the bevacizumab is to be administered to the patient in combination with the chemotherapy regimen.
Patent NZ-606180-A (NZ)
Title: (20r,25s)-2-methylene-19,26-dinor-1α, 25-dihydroxyvitamin d3 in crystalline form
Inventor: DELUCA HECTOR F
IPC: C07C401/00
Filed: 2011-09-28
Abstract: Provided is a method of purifying (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3, depicted in formula (I), to obtain the compound in crystalline form. Further provided is a crystalline form of (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 . The method includes preparing a solvent of methanol and water, dissolving a product containing (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 crystals, and recovering the crystals.
Patent NZ-609165-A (NZ)
Title: Tool for clamping sides of workpieces
Inventor: YANZHAO ZHU
IPC: B23Q3/06
Filed: 2012-05-20
Abstract: An array of elastic bodied clamping seats 2 is fixed on a soleplate 1 opposite clamp elements 9 with V-shaped receiving bays for the boxes 13 to be machined. By tightening the bolts 7 into the threaded holes 5 at the bottom of the seats, the V-shaped pressing blocks 6 are forced into the V-shaped grooves opening upwardly in the seats, so that the sides of the seats are moved outwardly D to clamp against the sides of the boxes 13 and prevent the boxes from moving and lifting whilst being machined.
Patent NZ-616409-A (NZ)
Title: Parasiticidal dihydroisoxazole compounds
Inventor: AN ZENGYUN
IPC: C07D495/04
Filed: 2012-05-08
Abstract: Disclosed are dihydroisoxazole compounds of formula I where the substituents are as defined herein for example 3-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((R)-2- oxopyrrolidin-3-yl)-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxamide. The compounds are intended for use for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. Also provided are compounds and processes useful for making the dihydroisoxazole compounds.