baber/WOPTO huggingface dataset:
Patent RU-2509080-C9 (RU)
Title: Замещенные дигидропиразолоны в качестве ингибиторов hif-пролил-4-гидроксилазы
Inventor: JESKE MARIO
IPC: A61K31/5355
Filed: 2009-04-11
Granted: 2014-08-20
Abstract: Изобретение относится к новым замещенным дигидропиразолонам формулы (I) и его фармацевтически приемлемым солям, обладающим свойствами ингибитора HIF-пролил-4-гидрооксилазы. Соединения могут найти применение для получения лекарственного средства, пригодного для применения в способе лечения и/или профилактики сердечно-сосудистых заболеваний, сердечной недостаточности, анемии, хронических заболеваний почек и почечной недостаточности. В соединении формулы (I) 
     
       
     
     X означает N или CH, R 1  означает водород или циано, R 2  означает насыщенный 4-7-членный остаток гетероциклила, связанный через атом азота, который содержит от 1 до 2 гетероатомов, выбранных из N и O. Причем гетероциклильный остаток может быть замещен одним заместителем, выбранным из группы, состоящей из C 3 -C 6 -циклоалкила, или 1-4 атомами фтора. Изобретение также относится к способу получения соединений и лекарственному средству на их основе. 5 н. и 11 з.п. ф-лы, 1 табл., 29 пр.
Patent RU-2595098-C9 (RU)
Title: Pneumatic tyre
IPC: B60C11/11
Filed: 2012-07-27
Granted: 2017-01-16
Abstract: FIELD: machine building. 
     SUBSTANCE: invention relates to automotive industry. Proposed tire comprises support elements, each being provided with row of ledges arranged in tire lengthwise direction. Ledge has radial outer surface of wall extending from surface of support element, radial inner surface of wall extending from surface of support element, and top surface extending between radial wall inner surface and radial external surface of wall. Radial outer surface of wall begins to rise from surface of support element at certain distance from tread edge so that minimum radial distance Kmin from tread edge to ledges makes from 5 to 15 mm. 
     EFFECT: technical result is improvement of characteristics of movement on snow-covered roads. 
     4 cl, 7 dwg, 2 tbl
Patent RU-2670952-C9 (RU)
Title: Система, генерирующая аэрозоль, для генерирования и управления количеством частиц соли никотина
Inventor: SILVESTRINI Patrik Charlz
IPC: A24F40/30
Filed: 2014-12-12
Granted: 2018-11-26
Abstract: Изобретение относится к системе, генерирующей аэрозоль, для доставки аэрозоля пользователю, включающей устройство, генерирующее аэрозоль, и изделие, генерирующее аэрозоль, и, в частности, к курительному устройству для доставки частиц соли никотина в виде аэрозоля пользователю в количествах, управляемых пользователем, и к устройству, генерирующему аэрозоль, для вмещения изделия, генерирующего аэрозоль. Система, генерирующая аэрозоль, содержит устройство, генерирующее аэрозоль, во взаимодействии с изделием, генерирующим аэрозоль; при этом изделие, генерирующее аэрозоль, содержит первое отделение, содержащее летучую жидкость, и второе отделение, содержащее соединение, улучшающее доставку; при этом устройство, генерирующее аэрозоль, содержит наружный корпус, приспособленный для приема изделия, генерирующего аэрозоль; блок питания; по меньшей мере один нагреватель, выполненный с возможностью получения питания от блока питания и выполненный с возможностью нагрева первого отделения при размещении изделия, генерирующего аэрозоль в наружном корпусе; устройство ввода, выполненное с возможностью приема нескольких дискретных входных данных от пользователя, при этом каждые отдельные входные данные соответствуют соответствующему дискретному количеству летучей жидкости в виде аэрозоля, требуемому пользователем; и контроллер, выполненный с возможностью управления величиной мощности, подаваемой по меньшей мере на один нагреватель, посредством изменения коэффициента заполнения, при этом каждые дискретные входные данные соответствуют соответствующему дискретному коэффициенту заполнения, таким образом, количество летучей жидкости в виде аэрозоля определено данными, введенными пользователем. Техническим результатом изобретения является предоставление пользователю управления генерируемым аэрозолем, доставляемым пользователю. 2 н. и 13 з.п. ф-лы, 3 ил.
Patent DK-62885-D0 (DK)
Inventor: HAKEN PIETER TEN
IPC: A01N37/46
Filed: 1985-02-11
Abstract: The invention provides N-acyl amino acid derivatives of general formula <CHEM> salts and esters thereof, wherein X represents an oxygen or sulphur atom, R<1> is an optionally substituted alkyl, alkenyl, cycloalkyl, aryl or aralkyl group or an optionally substituted alkylamino, cycloalkylamino, arylamino or aralkylamino group, R<2> is an optionally substituted alkyl, cycloalkyl or aryl group and R<3> is a hydrogen atom or an optionally substituted alkyl, cycloalkyl or aryl group; processes for their preparation and their use as fungicides.
Patent DK-83589-D0 (DK)
Inventor: GOELDNER DR WOLFGANG
IPC: C08G18/80
Filed: 1989-02-23
Abstract: Stone chip protection coatings have hitherto been prepared on the basis of solvent-containing basecoats. The novel process should be environmentally friendly through the use of aqueous systems. 
<??>A process for the preparing of a stone chip resistant coating by applying a stone chip protection layer based on from 30 to 60% by weight of carboxyl-containing polyesters or (meth)acrylates and copolymers thereof with vinyl compounds having an average acid number of 30 - 100 mg of KOH/g and an average OH number of 50 - 250 mg of KOH/g, neutralised with nitrogen bases, from 5 to 25% by weight of a water-soluble or water-dispersible blocked isocyanate prepolymer, from 15 to 30% by weight of water, and from 10 to 50% by weight of pigments, fillers and/or auxiliary and additive substances, wet-on-wet coating with an aqueous filler, conjoint baking, and topcoating. 
<??>Use of aqueous materials for the preparation of stone chip resistant coatings.
Patent DK-173587-D0 (DK)
Inventor: GERHARD HELMUT
IPC: B61D5/00
Filed: 1987-04-03
Abstract: PCT No. PCT/DE86/00341 Sec. 371 Date Jun. 23, 1987 Sec. 102(e) Date Jun. 23, 1987 PCT Filed Aug. 25, 1986 PCT Pub. No. WO87/01101 PCT Pub. Date Feb. 26, 1987.When a transport tank for transporting liquids is to be transported with only a partial load, the slosh forces occurring in this case may be reduced by means of slosh guard elements adapted to be built into the already existing tank. The slosh guard elements comprise strips of material bent generally to OMEGA -shape, which are fixed in the region of the opening of the OMEGA -shape to rails having cross profile. The rails and the slosh guard elements are dimensioned such that they can be introduced through the manhole provided in the tank outer wall.
Patent DK-224683-D0 (DK)
Inventor: RENNIE GEORGE KEER
IPC: D06F58/20
Filed: 1983-05-19
Abstract: A device for conditioning fabrics in the tumble-dryer comprises a powdered conditioning agent inside a permeable container, for example a sachet of paper, nonwoven fabric or plastics film, which in turn is inside an outer, substantially form-retaining, apertured container. The outer container is of a shape, for example, spherical, which allows ready movement among the tumbled fabrics. As it moves, the article gives more uniform and efficient conditioning than articles in the form of a sheet substrate impregnated with a solid conditioning agent.
Patent DK-238384-D0 (DK)
Inventor: HERSCHLER ROBERT J
IPC: A61K9/16
Filed: 1984-05-14
Abstract: Methylsulfonylmethane (CH3SO2CH3) administered orally is effective in ameliorating the symptoms of gastrointestinal upset, e.g., produced by the ingestion of aspirin and other pharmaceuticals, and of allergic reactions. Oral compositions containing a mixture of such a pharmaceutical and methylsulfonylmethane are useful in avoiding the gastrointestinal upset which otherwise occurs when ingesting the former.
Patent DK-249485-D0 (DK)
Inventor: ULITZUR SHIMON
IPC: C12R1/46
Filed: 1985-06-03
Abstract: A method for determining the presence of microorganisms in a test sample. Exogenous DNA containing a luminescent system or other genetic marker system derived from a suitable donor source is introduced by genetic means into a host microorganism which lacks or poorly expresses the donor DAN and whose presence it is desired to detect. Expression of the donor gene system allows the detection of the host microorganism. Compositions of bacteriophages and plasmids a well as a method for detection of antibiotics in a test sample are described.
Patent DK-253487-D0 (DK)
Inventor: FISCHER ARTUR
IPC: F16B13/02
Filed: 1987-05-19
Abstract: 1. Expansible fixing plug of plastics material which is slit transversely for a part of its length, the fixing plug having an internal bore tapering towards the front end for receiving a fastening screw, characterised in that, to match a bored hole provided with a V-shaped undercut, the external contour of the expansible fixing plug has a cylindrical portion and, following thereon in the region of the front end, a flared enlargement which is compressible to the diameter of the cylindrical portion by virtue of suitable widths of slit.
Patent DK-305885-D0 (DK)
Inventor: AGGARWAL BHARAT BHUSHAN
IPC: C07K14/525
Filed: 1985-07-04
Abstract: Methods and compositions are provided for the purification of a protein identified as tumor necrosis factor from nonrecombinant and recombinant sources, the preparation of nucleic acid encoding this tumor necrosis factor and for its expression in recombinant hosts. This tumor necrosis factor is used in the therapeutic treatment of malignant tumors, either alone or in synergistic combination with an interferon.
Patent DK-323183-D0 (DK)
Inventor: LABEEUW BERNARD
IPC: C07D501/36
Filed: 1983-07-13
Abstract: The present invention relates to cephalosporins having the formula: <IMAGE>  (1)  in which COOA is an acidic radical, salt or ester, and R1 represents a group:   <IMAGE>  in which RA and RB are H or alkyl or together form a cycloalkyl with the carbon to which they are bonded, R2 and R3 are H, alkyl or alkenyl, R4 and R5 are H, alkyl or alkenyl or together form a ring to the nitrogen atom with which they are bonded. This invention also relates to a process for the preparation of these compounds and to drugs containing them.
Patent DK-327083-D0 (DK)
Inventor: TAUSCHMANN OTTO
IPC: F16L/
Filed: 1983-07-15
Abstract: The piping for liquid and/or gaseous fluids comprises an outer pipe (1) and at least one inner pipe (2) which surrounds a fluid pipe (3) maintained sliding particularly axially by means of slide blocks. The space between the inner pipe (2) and the fluid pipe (3) contains air. The inner pipe (2) is thermally insulated from the outer pipe (1) on its entire length by means of a synthetic elastic foam. The piping is essentially used for remote heating conduits, and for refrigerant conduits, of petrol and natural gas.
Patent DK-345184-D0 (DK)
Inventor: HOLMWOOD GRAHAM
IPC: A01N43/54
Filed: 1984-07-13
Abstract: Combating fungi and/or regulating the growth of plants with novel aroxy-pyrimidinyl-alkanols of the formula   <IMAGE>   in which R is optionally substituted naphthyl, or   <IMAGE>   Y each independently is halogen, alkyl, cycloalkyl, alkoxy, halogenoalkyl, halogenoalkoxy, alkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkoxy or optionally substituted phenylalkyl, or addition products thereof with acids or metal salts.
Patent DK-407887-D0 (DK)
Inventor: KAPER LOURIS
IPC: C07D473/12
Filed: 1987-08-05
Abstract: This invention relates to a process for recovering caffeine from laden activated carbon by treating the laden activated carbon with an organic acid. In order to achieve good extraction efficiencies, on the one hand, and to avoid problems with the flash point, such as with acetic acid, on the other hand, the process according to the invention is characterized by treating the activated carbon with a mixture comprising at least 65% by weight of acetic acid and at least 2% by weight of citric acid.
Patent DK-474087-D0 (DK)
Inventor: FOX RODNEY THOMAS
IPC: A61L9/04
Filed: 1987-09-11
Abstract: A device for dispensing a volatile liquid as a vapour includes a porous support of natural or synthetic woven or non-woven fibre, porous glasses, porous plastics (optionally in film form), parchment, leather or rubber provided with an organopolysiloxane material which serves to close the pores of the support to the passage of liquid but permits the passage of vapour from the liquid. The volatile liquid is a perfume, insecticide, insect repellant, insect attractant, higher animal repellant, corrosion inhibitor, a germicidal agent or a medicament. A space treatment vapour emanating device is thus provided the external surface of which device is dry to the touch.
Patent DK-513789-D0 (DK)
Inventor: BREWSTER ANDREW GEORGE
IPC: A61K31/46
Filed: 1989-10-16
Abstract: The invention concerns novel, pharmaceutically useful 1,3-dioxane alkenoic acid derivatives of the formula I containing a pyridyl moiety at position 4 of the dioxane ring and in which the groups at positions 2, 4 and 5 have cis-relative stereochemistry, X is hydrogen, alkoxy or hydroxy, Y is vinylene, n is 1 or 2, A<1> is alkylene, the substituents R<1> and R<2> at position 2 of the dioxane ring have a variety of values defined hereinafter, and R<4> is hydroxy, a physiologically acceptable alcohol residue or alkanesulphonamido, and the pharmaceutically acceptable salts thereof. The invention also includes processes for the manufacture and use of the acid derivatives as well as pharmaceutical compositions for therapeutic use in one or more of a variety of diseases such as ischaemic heart disease, cerebrovascular disease, asthmatic disease and/or inflammatory disease. <CHEM> l
Patent HU-912994-D0 (HU)
Title: Method for producing morpholine derivatives of doxorubicine and pharmaceutical preparatives containing said compounds
Inventor: BARGIOTTI ALBERTO
IPC: C07C43/174
Filed: 1990-12-18
Abstract: Morpholinyl derivatives of doxorubicin having the general formula A:   <CHEM> wherein X represents a linear or branched C1-c6 alkyl group or a benzyl group -CH2C6H5, and having (S) or (R) configuration at carbon atom C-2" of the morpholino ring, are antitumor agents.
Patent HU-905376-D0 (HU)
Title: Television receiver for selectable processing of bas or bas and separated f signals
Inventor: LAMY CHRISTOPHE
IPC: H04N9/64
Filed: 1990-06-15
Abstract: A television system comprises a first input terminal (20) for providing a composite video (CSCC) signal or a separated luminance (SCC) signal, and a second input terminal (15) for providing a separated chrominance (C) signal. A change-over switch (11) has a first input (a) coupled to the first input terminal (20) through a path including a color sub-carrier filter (9), a second input (b) coupled to the second input terminal (15) through a path not including the color sub-carrier filter (9), and an output (c) coupled to the input (d) of a color decoder (8). The change-over switch couples the input (d) of the color decoder (8) to the first input terminal (20) in a first position (a), and couples the input (d) of the color decoder (8) to the second input terminal (15) in a second position (b). A sub-carrier detector (CK) is coupled to the output (c) of the change-over switch (11) for detecting the presence or absence of a color sub-carrier. A control unit initially causes the change-over switch ( 11) to be in the first position (a) and thereafter causes said change-over switch (11) to remain in the first position (a) if a color sub-carrier is present at the output (c) of the change-over switch (11), but causes the change-over switch (11) to be in the second position (b) if a color sub-carrier is not present. Once the change-over switch (11) is in the second position (b), the control unit (1) causes said change-over switch (11) to be switched back to said first position (a) from said second position (b) if a color sub-carrier is still not present.
Patent NO-874906-D0 (NO)
IPC: D06N3/04
Filed: 1987-11-25
Abstract: PCT No. PCT/DK87/00026 Sec. 371 Date Nov. 25, 1987 Sec. 102(e) Date Nov. 25, 1987 PCT Filed Mar. 26, 1987 PCT Pub. No. WO87/05953 PCT Pub. Date Oct. 8, 1987.By using a hot melt adhesive sheet a fabric is adhered to at least one side of an air cell sheet of polyethylene after radiation with  beta -or  gamma -rays. The material combines great strength and flexibility with good thermal insulating ability and low weight together with great and permanent buoyancy in water.
Patent NO-890587-D0 (NO)
Inventor: OOYEN ALBERT JOHANNES JOSEPH V
IPC: C12N15/64
Filed: 1989-02-10
Abstract: Novel polypeptides having Factor VIII activity are provided as well as compositions and methods for their preparation. The polypeptides comprise derivatives and fragments of Factor VIII and have sequences substantially similar to portions of naturally occuring Pactor VIII. The polypeptides find use in treatment of Hemophilia A.
Patent NO-892880-D0 (NO)
Inventor: GUILHEM CHRISTIAN
IPC: B68G7/05
Filed: 1989-07-12
Abstract: In a process for covering an object by means of at least one flexible piece, a fluidized bed of particles (8) is covered by a flexible cloth (10), the flexible covering piece (12) is placed above said cloth, the object (13, 14) is placed above said cloth, pressure is applied to said object, deforming the flexible sheet and immersing the object in the fluidized bed until a mating imprint is formed in the latter. The covering can be effected by gluing, in particular with a previously applied heat-activated adhesive in which case the fluidized bed is obtained by means of a current of hot air at a temperature above the activation temperature of the adhesive. The process is particularly suitable for assembling and mounting seat covers. Also described is a device for implementing the process.
Patent NO-903737-D0 (NO)
Inventor: KULZER ERNST
IPC: H04M1/00
Filed: 1990-08-24
Abstract: Operating functions, on the basis of which a switching device can be set as required, but which are to some extent mutually exclusive, are assigned individually to the function keys in an input keyboard. Input information is fed to an evaluation logic circuit which, when a combination of mutually exclusive functions is entered, converts this combination into an alternative combination of functions. An alternative combination is selected of the type which, in comparison with the originally entered combination, has the minimum number of function changes. The functions are displayed according to the alternative combination by means of a display device. <IMAGE>
Patent NO-911688-D0 (NO)
Inventor: HOHN ANDREAS
IPC: C12P21/00
Filed: 1991-04-29
Abstract: NT3 is a member of the DBNF gp. It is based in part on the identification of regions of nucleic acid sequence homology shared by BDNF and NGF. The regions of homology may be used to identify new members of the BDNF/NGF gene gp. See US application No. 400,591 filed 30 August, 1989. The purified NT-3 protein and its prodn. by growing a host cell comprising the DNA molecule are claimed. The protein may be glycosylated or unglycosylated. Antibodies to NT-3 are also claimed and are produced by immunising a host animal with a neurotrophin-3 protein or its fragment.
Patent NO-911774-D0 (NO)
Inventor: KVISTEROEY TERJE
IPC: H01L/
Filed: 1991-05-06
Abstract: The invention relates to an arrangement for the encasing of a functional device, e.g., a semiconductor element, a semiconductor-based element, a sensor element, a microactuator, or an electronic circuit consisting of one or more integrated circuits and other electronic components, and a process for preparing an arrangement of this kind. Around the functional device (47) is arranged a casing (43, 45) which forms a closed cavity (51) which completely or partly surrounds the functional device (47). The casing is made of a plastic material or another polymer material. The casing consists of two or more joined components (43, 45). Metal parts which form wire bonds (46) with said functional device (47) in the casing pass through the walls of said casing. At least one of the casing pass through the walls of said casing. At least one of the casing components has filling holes or filling ducts (52, 53) for the introduction of liquid and/or gel material (56) into said cavity, and the filling holes or filling canals are sealed (54, 55) after the volume of the cavity has been filled with said liquid or gel.
Patent NO-923207-D0 (NO)
Inventor: BOURZAT JEAN-DOMINIQUE
IPC: C07K5/00
Filed: 1992-08-17
Abstract: PCT No. PCT/FR91/00119 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Feb. 14, 1991 PCT Pub. No. WO91/12265 PCT Pub. Date Aug. 22, 1991.This invention relates to compounds of formula:    <IMAGE>  (I)  in which R1 represents a hydrogen atom or an alkyl or alkoxycarbonyl radical or an unsubstituted or substituted phenyl radical, R2 represents an alkyl (1-8 C) or polyfluoroalkyl radical or an unsubstituted or substituted cycloalkyl radical, R3 represents an unsubstituted or substituted phenyl radical, a naphthyl, indolyl, quinolyl or phenylamino radical in which the phenyl ring is optionally substituted, or a quinolylamino radical, and m is 0 or 1, the process for preparing them and the medicaments containing them.
Patent NO-932736-D0 (NO)
Inventor: CATANIA JOSEPH S
IPC: A61K9/00
Filed: 1993-07-29
Abstract: A pharmaceutical composition having reduced bitterness consisting of a bitter pharmaceutical agent, a taste-masking component and a pharmaceutically acceptable carrier. The taste-masking component is an alkaline earth oxide, an alkaline earth hydroxide or an alkaline hydroxide and does not interfere with the activity of the pharmaceutical agent.
Patent NO-940915-D0 (NO)
Inventor: ALLSHOUSE GARY W
IPC: D21B1/14
Filed: 1994-03-15
Abstract: A method and apparatus is disclosed for calibrating a gap sensing probe (12) in a refiner having first (76) and second (80) grinding plates facing each other and supported by respective first and second plate holders, each grinding plate having a face (78, 82) defining a grinding gap (86). The gap measuring device, which is secured within one of the plates, includes a sensor probe (12) for measuring gap width data having a substantially cylindrical tip (14) with a flat frontal portion (16), an attached conical portion (18) and a longitudinal axis (20) therebetween. A cable (22) is electrically connected to the conical portion of the probe, for transmitting the gap width data. A protective sleeve (24) can be positioned around and contact the cylindrical tip, wherein the flat frontal portion of the tip is exposed through the sleeve. A substantially crucible-shaped ceramic housing (28) having a closed front (30), an open back (32) is provided, wherein the flat frontal portion of the tip abuts the front of the housing and the cable protrudes from the rear of the housing. A threaded mounting adapter (42) is situated around the housing and an adapter plug (60) is situated within the mounting adapter. The housing, the mounting adapter, and the adapter plug have flanges (38, 48, 68) and shoulders (52) which interact so as to prevent movement of the housing. In the preferred embodiment, the probe is calibrated from the rear of the housing by turning the probe by the threaded mounting adapter. The calibration can be completed without actually measuring the plate gap width by rotating the probe through threads which are of a known and predetermined width. <IMAGE>
Patent NO-941038-D0 (NO)
Inventor: SEINER JEROME ALLAN
IPC: C08J7/048
Filed: 1994-03-22
Abstract: The shelf life of polymeric containers may be economically extended by coating with a barrier material having less than half the permeability of the substrate polymer, the coating being applied to 30 to 75 percent of the container's area, with the proviso that the uncoated area has an average permeability of no more than 15 cc-mm per square meter per day per atmosphere.
Patent NO-943895-D0 (NO)
Inventor: KOSLEY JR RAYMOND WALTER
IPC: C07D223/02
Filed: 1994-10-14
Abstract: This application relates to compounds of the formula <CHEM> wherein R<1>, R<2> and R<3> are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, pharmaceutical compositions containing the compounds and methods for making and using the compounds.