baber/WOPTO huggingface dataset:
Patent NZ-237431-A (NZ)
Title: 1-carboxyalkylquinoxaline-2,3-dione derivatives and medicaments
Inventor: JORGENSEN ANKER STEEN
IPC: A61P25/20
Filed: 1991-03-14
Abstract: 1-carboxyalkylquinoxaline-2,3(1H,4H)-dione compounds or tautomeric forms thereof of the formula   <IMAGE>  wherein R represents hydrogen, C1-6-alkyl, including branched chains, or aralkyl and n represents the number from 0 to 5; R4 represents hydrogen or hydroxy; R5, R6, R7 and R8 independently represent hydrogen, nitro, halogen, alkoxy, aryloxy, aralkoxy, C1-6-alkyl including branched chains, or aryl; R9 represents hydrogen, lower alkyl, or aryl; R10 represents hydrogen, or alkyl. The compounds are useful in the treatment of neurological and psychiatric diseases.
Patent NZ-237557-A (NZ)
Title: Casting metal strip with a pair of parallel rolls; components assembled from remote preheat locations
Inventor: HISAHIKO FUKASE
IPC: B22D11/06
Filed: 1991-03-25
Abstract: Method and apparatus for casting metal strip in which molten metal is introduced between a pair of parallel casting rollers (16) via a tundish (18) and metal delivery nozzle (19). Casting rollers (16) are cooled so that shells solidify on the moving roller surfaces and are brought together at the nip between them to produce a solidified strip product (20) at the roller outlet. The tundish (18), delivery nozzle (19) and a pair of side closure plates (56) to confine the pool of metal on the casting rollers are separately preheated to working temperature and then rapidly brought into an operative assembly and casting is started before detrimental uneven or localized cooling of the preheated components can develop. To this end the casting rollers are mounted on a carriage (13) movable between a first station (14) at which the preheated components are fitted and a second station (15) at which casting is carried out.
Patent NZ-331034-A (NZ)
Title: Gate switch for electrified security system with electrical conductor moved to complete or break internal circuitry of gate switch
Inventor: THOMSON BRADLEY JOHN
IPC: E04H17/00
Filed: 1999-07-13
Abstract: witch 1 is located at an electric fence gate and has probes 2,3 which operate in a known manner to maintain circuit continuity.  When the gate is opened a bolt (not shown) connected to probes 2,3 internally contacts bar 4 and when the gate is shut the probes are retracted against springs (not shown), so in both cases electrical continuity is maintained.  The invention includes bolt 6 which when installed connects bar 4 to ground plate 8, and when removed disconnects bar 4 from ground plate 8.  This facility allows for selective alarm actuation dependent on whether or not bolt 6 is installed.
Patent NZ-332030-A (NZ)
Title: Sulfonamide substituted chromans, processes for their preparation, their use as a medicament and pharmaceutical preparations comprising them
Inventor: BRENDEL JOACHIM
IPC: C07D409/04
Filed: 1998-09-24
Abstract: The compound of formula I blocks the potassium channel opened by cAMP. R1 and R2 are independently H, CF3, C2F5, C3F7, alkyl with 1-6 carbons, or a substituted or unsubstituted phenyl; or R1 and R2 together are an alkylene chain with 2-10 carbon atoms. R3 is R(10)-Cn H2n-NR(11) or R(10)-CnH2n-, (wherein R(10) is H, methyl, cycloalkyl with 3-8 carbons, CF3, C2F5 or C3F7; R(11) is H or an alkyl with 1-6 carbons; and one CH2 group in CnH2n can be replaced by -O-, -CO-, -S- or other group). R4 is R(13)-CrH2r, (wherein R(13) can be H, CF3, C2F5, C3F7, a cycloalkyl with 3-8 carbon atoms or other group; and one CH2 group in CrH2r can be replaced by -O-, -CO-, -S- or other group).  At least one of R5, R6, R7 and R8 is Y-CsH2s-R(18), (wherein R(18) is substituted phenyl, substituted N-containing heterocycle with 1-9 carbons or other group), thienyl, furyl or an N-containing heterocycle with 1-9 carbons. The remaining substituents of R5, R6, R7 and R8 are independently H, F, Cl, Br, I, alkyl with 1-5 carbon atoms, cycloalkyl with 3-8 carbons, CN, NO2, OR(12e) or NR(12e)R(12f), (wherein R(12e) and R(12f) are independently H or an alkyl with 1-4 carbons). R9 is H, OR(12g) or OCOR(12g), wherein R(12g)  is H or alkyl having 1-3 carbons. B is hydrogen, or together with R9 is a bond. The compound or a physiologically tolerable salt thereof is used in a medicament for therapy of cardiovascular disorders, the treatment of ulcers of the gastrointestinal area or the treatment of diarrheal disorders.
Patent NZ-334938-A (NZ)
Title: Pressure reducing valve for LP hot water cylinder, pressure sensitive member varies in size with changes in pressure
Inventor: BRADLEY PETER MICHAEL
IPC: G05D16/06
Filed: 1999-03-31
Abstract: Fluid enters high pressure inlet 9 and via an aligned aperture 22 in tube 20 to outlet 6.  As pressure builds up at outlet 6 (for example where the valve is supplying water to a hot water heater) flexible member 2 moves stretches downwardly taking tube 20 down and closing off inlet 9.  On higher pressure aperture 22 is aligned with relief outlet 10.  Other forms of valve construction are disclosed.
Patent NZ-501415-A (NZ)
Title: Benzimidazole derivatives (optionally with saccharide substituents) useful for the treatment or prophylaxis of viral infections (particularly herpes, cytomegalovirus and Hepatitis B) or for the treatment or prophylaxis of restenosis
Inventor: DRACH JOHN CHARLES
IPC: C07D235/18
Filed: 1998-06-08
Abstract: The benzimidazole derivative of formula (I) or salt or pharmaceutical composition thereof, where in the formula (I):  R1 is halogen, hydroxy, azido, alkyl, alkoxy, alkenyl, alkynyl, arylalkenyl, arylalkynyl, or -NR19R20 (where R19 and R20 may be the same or different and are H, alkyl, cyanoalkyl, hydroxyalkyl, haloalkyl, cycloalkyl, alkylcycloalkyl, alkenyl, cycloalkylalkyl, alkynyl, aryl, arylalkyl, heterocyclealkyl, alkylcarbonyl, arylsulfonyl, or R19R20 together with the N atom to which they are attached from a 3, 4, 5 or 6 membered heterocyclic ring), OR21 (where R21 is H, alkyl, cycloalkyl, or aryl), or SR22 (where R22 is H, alkyl, hydroxyalkyl, cycloalkyl, or aryl). R2 is H or halogen. R3 and R4 may be the same or different and are H, halogen, alkyl, aryl, heterocyclearyl, alkoxy, haloalkyl or -SR24 (where R24 is H, alkyl, aryl, or arylalkyl). Z is a substituent of formula (la) or (Ib), wherein: R5 is H, alkyl, haloalkyl or alkoxy. R6 is H, hydroxy, halogen, alkyl, hydroxyalkyl, haloalkyl or alkoxy. R7 is H, hydroxy, halogen, alkyl, hydroxyalkyl, haloalkyl, alkoxy, or R6 and R7 together form a ketone or alkene. R8 - R11 may be the same or different and are H, hydroxy, halogen, alkyl, hydroxyalkyl, haloalkyl, alkoxy, or any of R8 and R9 or R10 and R11 together form a ketone or alkene. R12 - R14 may be the same or different and are H, hydroxy, alkyl or hydroxyalkyl. With the following provisos: i) The compound of formula (I) cannot be 2,5-dimethyl-1-(2,3,4-tri-O-acetyl-beta-D-xylopyranosyl)-1 H-benzimidazole or 5,6-dimethyl-1-(2,3,4-tri-O-acetyl-beta-D-arabinopyranosyl)-benzimidazole-2-thione. ii) When Z is a substituent of formula (la) R2, R3, and R4 cannot all be H. iii) When Z is a substituent of formula (la) or (Ib) R1 cannot be NR19R20 where R19 and R20 together with the N atom to which they are attached form a 5 membered heterocyclic ring containing S. The compound or salt of formula (I) is used for the treatment or prophylaxis of a viral infection (especially herpes, cytomegalovirus and Hepatitis B) or for the treatment or prophylaxis of restenosis.
Patent NZ-505370-A (NZ)
Title: Indole derivatives and pharmaceuticals thereof for the inhibition of factor Xa
Inventor: DEFOSSA ELISABETH
IPC: A61K31/403
Filed: 1998-12-10
Abstract: Compounds of the formula I, wherein: Two of the residues R1a, R1b, R1c and R1d independent of one another are H, F, Cl, Br, I, alkyl, CF3, phenyl, phenylalkyl-, alkoxy, phenyloxy-, phenylalkoxy-, OH, NO2, -NR5aR5b, -NR5b-SO2-R6a, -S-R6b, -SOn-R6c, -SO2-NR5aR5b, -CN or -CO-R7, and are identical or different, and the other two of the residues R1a, R1b, R1c and R1d are H; One of the residues R2 and R3 is -(CH2)p-CO-R8 and the other is H, F, Cl, Br, alkyl or -(CH2)p-CO-R8; Or R2 and R3 together form a group of the formula -CH2-CH2-N(-CO-R20)-CH2- wherein R20 is optionally substituted phenyl, phenylalkyl-, pyridyl or pyridylalkyl-; A is a direct linkage, a divalent -alkyl- residue which is saturated or which contains a double bond or a triple bond, -CO-, -SOr -, -CO-alkyl-, -alkyl-CO- or -alkyl-CO-NH- wherein the nitrogen is bonded to R4; R4 is phenyl which is substituted by one residue R15c and which can additionally be substituted by one or two substituents from the series consisting of alkyl, F, Cl and Br, or R4 is pyridyl which is unsubstituted or substituted at the nitrogen atom by R14, or R4 is the residue Het which is substituted by R15d; Also described is a pharmaceutical composition, comprising at least one compound of the formula I or their physiologically acceptable salts together with a pharmaceutically acceptable carrier.
Patent NZ-511430-A (NZ)
Title: Controlled release bead of up to four layers where a thick layer of a water-insoluble polymer has been applied to an inert core as a sealcoat
Inventor: GREN TORKEL
IPC: A61P13/10
Filed: 1999-11-11
Abstract: A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.
Patent NZ-513374-A (NZ)
Title: Conditioning tunnel for fabric articles and clothes to be vacuum packed
Inventor: ENBOM SVEN AKE
IPC: B65B25/20
Filed: 1998-03-02
Abstract: Clothes or fabric articles to be vacuum packed for shipping are carried on conveyor 10 through a tunnel 2 to be conditioned.  Conditioning air is extracted at 22 from the ceiling 6 of the tunnel, transported to a dehumidifier, and the dehumidified air is reintroduced to the tunnel via inlets 18 passing through the sidewalls of the tunnel.  The inlets are provided with fans 14 for circulation of the air into the tunnel and heating grills 24 to regulate the temperature of the input air.  This arrangement of air input and output provides for a more even conditioning of the fabrics and a shorter tunnel conditioning time.
Patent NZ-515145-A (NZ)
Title: Broad spectrum antimicrobial mixtures
Inventor: SMITH ROGER ERROL
IPC: A01N43/70
Filed: 2000-04-27
Abstract: An antimicrobial composition comprising; (a) an iodopropynyl compound selected from the group consisting of 3-iodo-2-propynyl propyl carbamate, 3-iodo-2-propynyl butyl carbamate, 3-iodo-2-propynyl hexyl carbamate, 3-iodo-2-propynyl cyclohexyl carbamate and 3-iodo-2-propynyl phenyl carbamate, and (b) 2-(methoxycarbonylamino)benzimidazole. Wherein the iodopropynyl compound and the 2-(methoxy-carbonylamino)benzimidazole are present in a proportion of from about 100 parts 2-(methoxycarbonylamino)benzimidazol to one part of the iodopropynyl compound to greater than two parts 2(methoxycarbonylamino)benzimidazole to about one part of the iodopropynyl compound.
Patent NZ-516249-A (NZ)
Title: Novel naphthylsulfonic acids and related compounds as glucose uptake agonists
Inventor: SPEVAK WAYNE R
IPC: C07C311/46
Filed: 2000-07-28
Abstract: Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds are provided. Compounds of formula (1) where: R1 and R2 are, independently, hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, R3 is a substituent on the B ring; and is -SO2OR6, -C(O)OR6, -SO2NR62-C(O)NR62or tetrazolyl; the linker -WY- between the naphthyl and phenyl intersects the A ring of the naphthyl and is, independently, -C(O)NR7-, - NR7C(O)-, -C(O)O-, -OC(O)-, -CH=CH-, -NR7CH2-, -CH2NR7-, - NR7C(O)NR7- -NR7C(O)O-, -OC(O)NR7-, -NR7SO2O-, -OSO2NR7-, - OC(O)O-, -SO2NR7-, -NR7SO2-, -OSO2-, or -SO2O-; each R6 and R7 is, independently, hydrogen or lower alkyl; optionally in the form of single stereoisomers or mixtures of stereoisomers, or the pharmaceutically acceptable salts thereof; are useful in methods of stimulating the kinase activity of the insulin receptor, enhancing the activation of the insulin receptor by insulin, and stimulating the uptake of glucose into cells. A variety of antidiabetic compounds and pharmaceutical compositions comprising the antidiabetic compounds are also disclosed.
Patent NZ-517664-A (NZ)
Title: Chemically peeling agent comprising a phenol and polyethylene gycol
Inventor: UEDA SETSUKO
IPC: A61K8/90
Filed: 2000-09-06
Abstract: A chemical peeling agent is disclosed, which comprises: (1) a polyethylene glycol, a block polymer of ethylene oxide or propylene oxide, an alkyl alcohol or an alkenyl alcohol of formula: B-[-(CH2CH2O)m(AO)n-H]a wherein B is an alcohol residue; AO is C3-18 alkylene oxide; a is 1 or more; m is 4 or more; and n is 0, 1 or more, provided that a molar amount of m of ethylene oxide to be added is a value that amounts to 40% or more of the entire molecular weight of ethylene oxide chain moiety; and (2) a phenol compound, for example, salicylic acid, phenol or resorcinol formulated in an amount of 10% to 30% by weight.
Patent NZ-519664-A (NZ)
Title: A two way sealable bag
Inventor: FLANAGAN PETER ROSS
IPC: B65D27/14
Filed: 2002-06-20
Abstract: A two-use bag (1) suitable as a courier pouch or envelope is made from plastic film. The bag is made of longitudinally folding plastic film and transversely sealing and severing it at bag defining intervals. Thus the bag has a front cover (6) and a rear cover (5) separated at the bottom by the fold (7) and with side seals (8). The open side forms a primary mouth (9) and a primary closure flap (3) is attached to the rear cover adjacent to the primary mouth. The flap can be folded over the primary mouth and sealed to the front cover to close the bag. To that end a peelable adhesive strip (10) is provided on the free portion of the primary closure flap. A frangible section (5/6), defined by weakened lines (5d, 6d), is provided on the bag bordering the primary mouth. Removal of the frangible section enables access to the bag. A secondary mouth (12) is formed by the removal of the frangible section. A secondary closure section (4) is attached to the rear cover adjacently below the weakened lines and can be folded over the secondary mouth to close it. To that end a peelable adhesive strip (11) is provided on the secondary closure flap. In a modified form a frangible strip (6c) is provided as an extension of the front cover beyond the primary mouth. Identifying markings can be provided on the frangible section, the remainder of the bag and the frangible strip. The frangible strip can be removed prior to closing the primary mouth to provide a dispatch record. The frangible section can be retained as a receipt and second use record.
Patent NZ-520690-A (NZ)
Title: Recombinant production of human histone-1 subtypes and use thereof for therapeutic purposes
Inventor: POHLMEYER KAI
IPC: C07K14/47
Filed: 2001-01-11
Abstract: Recombinant human protein histone 1 produced in E.coli, the preparation thereof, and their use in therapeutic treatment.
Patent NZ-521033-A (NZ)
Title: N-alkylamide substituted hydroxamic acid derivatives useful as antibacterial agents
Inventor: HUNTER MICHAEL GEORGE
IPC: A61K31/16
Filed: 1999-02-05
Abstract: An N-formyl hydroxylamine derivative or a pharmaceutically or veterinarily acceptable salt thereof has formula (I) H-C(=O)-N(OH)-C(H)(R1)-C(H)(R2)-C(=O)-A wherein: R1 is hydrogen, alkyl or haloalkyl; R2 is R10-(ALK)m-; R10 is hydrogen or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or heterocyclic group; ALK is divalent alkylene alkenylene, or alkynylene radical, and may be interrupted by one or more non-adjacent -NH-, -O- or -S- linkages; m and n are independently 0 or 1; A' is a group of formula 1A, 1B, 1C or 1D; For formula 1A, 1B and 1C R3 and R4 when taken together with the nitrogen and carbon atoms to which they are respectively attached form an optionally substituted saturated heterocyclic ring of 5 to 8 atoms which ring is optionally fused to a carbocyclic or second heterocyclic ring; or for formula 1C R3 is hydrogen and R4 is the side chain of a natural or non-natural -a-amino acid; R5 and R6, independently represent hydrogen or optionally substituted alkyl, cycloalkyl, arylalkyl, non-aromatic heterocyclic, or heterocycloalkyl, or R5 and R6 when taken together with the nitrogen atom to which they are attached form an optionally substituted saturated heterocyclic ring of 3 to 8 atoms which ring is optionally fused to a carbocyclic or second heterocyclic ring and R7 is hydrogen, alkyl, or an acyl group provided that when R1 is H and A' is a group of 1D wherein R5 and R6 then R2 is not methyl. The compounds are used for treating bacterial infections.
Patent NZ-522460-A (NZ)
Title: Oligopeptides derived from epimorphin for promoting hair growth
Inventor: HIRAI YOHEI
IPC: A61P17/14
Filed: 2002-11-06
Abstract: An isolated oligopeptide of between about 5 and about 10 amino acid residues in length having hair growth promoting activity comprising the amino acid sequence selected from: X1-X2-X3-X4-X5-X6-X7, X1-X2-X3-X4-X6-X5-X7, X1-X2-X3-X-X6-X4-X5-X7 or X1-X2-X6-X3-X4-X5-X7; wherein X1 is Ser, Ala, Tyr, Pro, Phe, Val, Gly, Leu, Ile or Met or is deleted from the oligopeptide; X2 is Ile, Gly, Asn, Thr, Val, Ser, Phe, Leu, Ala, Pro, Cys or Met or is deleted from the oligopeptide; X3 is Glu, Lys, Gln, Arg, Ala, Val, Trp, Cys or Asp; X4 is Gln, Pro, Glu, Thr, Arg, Ser, His, Cys or Lys; X5 is Ser, trp, Phe, Thr, Cys, Tyr, Pro, Ala, Gly, Val, Leu, Ile or Met X6 is Cys , a reactive substance-bound Cys or a reactive substance-bound Lys; X6 is Asp, Glu, His, Ser, Ala, Gly, Asn, Tyr, Arg or Leu or is deleted from the oligopeptide; with the proviso that the oligopeptide is not identical to SEQ ID NO:1, SEQ ID NO:2, SER-Glu-Gln-Ser-Cys-Asp or Ser-Ile-Glu-Gln-Ser-Cys. A composition comprising the oligopeptide can be used in the manufacture of a medicament for promoting hair growth.
Patent NZ-522754-A (NZ)
Title: Adjustable water-fillable exercise weights
Inventor: BARBER STEPHEN
IPC: A63B21/06
Filed: 2001-04-26
Abstract: A readily portable dumbell or barbell for exercising and weight training is provided in which weight units on an elongated handle comprise front and rear end plates interconnected by a collapsible/expandible fluid receptacle in the form of a resilient bellows. The weight unit is lengthened and expanded when fluid is added and is shortened and decreased in volume when fluid is removed. Calibration means are provided for visually indicating the weight of the unit corresponding to the longitudinal spacing between the front and end plates of the unit. In a preferred embodiment, a visually readable measurement of weight is provided by means for a graduated bar insert which extends slidably within the hollow handle of the dumbell or barbell and moves therealong with expansion or contraction of the water-filled bellows.
Patent NZ-523742-A (NZ)
Title: Method and system for providing traffic and related information for a specific traveler profile
Inventor: TRAYFORD ROS
IPC: H04W4/024
Filed: 2001-06-26
Abstract: A system for providing traffic or related information comprises: a database storing historical traffic data and being operable to receive substantially real time traffic data and associated data; means for deterministically integrating the historical and real time traffic and associated data with respect to at least one traveler profile to produce customized forecasted traffic information with respect to the at least one traveler profile and means for sending the customized forecasted traffic information to an intended recipient wherein the customized forecasted traffic information comprises at least a predicted travel delay for at least one travel route described in at least one traveler profile wherein where there is insufficient traffic data for a link of the travel route, the means for integrating is operable to use available data in respect of a further link in place of the insufficient traffic data on the link of the travel route in order to provide the predicted travel delay.
Patent NZ-527596-A (NZ)
Title: Avermectins substituted in the 4"-position having pesticidal properties
Inventor: PITTERNA THOMAS
IPC: A01N47/12
Filed: 2002-02-26
Abstract: Disclosed herein is a compound of formula (I) in which, R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; R2 is H, unsubstituted or mono- to pentasubstituted C1-C12alkyl or unsubstituted or mono-to pentasubstituted C1-C12alkenyl; R3 is C2-C12alkyl, mono- to pentasubstituted C1-C12alkyl, unsubstituted or mono- to pentasubstituted C1-C6alkoxy-C1-C6alkyl, unsubstituted or mono- to pentasubstituted C3-C12cycloalkyl, C2-C12alkenyl, C2-C12alkynal; or R2 and R3 together are an alkylene or alkenylene bridge; with the provison that R1 is not sec-butyl or isopropyl if R2 is H and R3 is 2-hydroxyethyl, isopropyl, n-octyl or benzyl; or, if appropriate, in E/Z isomer, an E/Z isomer mixture and/or a tautomer thereof; a process for preparing and using these compounds and their tautomers; pecticides whose active compound is selected from these compounds and their tautomers; and a process for preparing these compounds and compositions, and the use of these compounds and compositions.
Patent NZ-532252-A (NZ)
Title: Fast unfolding two-layer temporary flooring structure
Inventor: DESCHAMPS GEORGES-PAUL
IPC: E01C9/08
Filed: 2002-10-10
Abstract: A fast unfolding two-layer temporary flooring structure consisting of preferably rigid plates (1 to 6), made of a suitable material. The temporary flooring structure is characterized in that the plates are arranged mutually parallel and cascade-linked by an articulated linking element (B) so that between two consecutive plates, the linking element is linked to an edge of the other plates, and also preferably in a central zone of the other plate, the linking elements defining hinge lines between parallel planes with longitudinal or transverse axis of the plates.
Patent NZ-534648-A (NZ)
Title: Method and apparatus for delivering server-originated information during a dormant packet data session
Inventor: CHEN AN MEI
IPC: H04B7/26
Filed: 2003-02-19
Abstract: A method and apparatus for delivering information to a dormant target mobile communication device is disclosed. The method provides for sending the information when no dedicated traffic channel is established. In one embodiment, the method provides for sending the information in short data bursts. The methods provide for a significant reduction in the actual total dormancy wakeup time by exchanging group call signalling even when the target mobiles are dormant and no traffic channel is active.
Patent NZ-535714-A (NZ)
Title: Programmable breastpump
Inventor: SILVER BRIAN H
IPC: A61M1/06
Filed: 2000-12-07
Abstract: A breastpump which can be programmed to generate, among other things, a plurality of differing milk expression (extraction) sequences, or curves is disclosed. In one embodiment of the invention, a motorized pump (e.g., compressed air, battery and/or house current) is provided with a microprocessor-based controller. Cards, with microprocessor "chips," containing different suction curves adapted for varying conditions and objectives are included for programming the controller in this embodiment.