baber/WOPTO huggingface dataset:
Patent IL-182093-A0 (IL)
Title: 3,6-substituted 5-arylamino-1h-pyridine-2-one derivatives and related compounds as poly(adp-ribose)polymerase (parp) inhibitors in the treatment of tissue damage or disease caused by necrosis or apoptosis
Filed: 2007-03-21
Abstract: This invention relates to compounds of formula (I), wherein R1 and R3 independently represent fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; R2 represents hydrogen, fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; X represents O, S, NH or N(C1-C3-alkyl); and Ar represents an unsubstituted or at least monosubstituted aryl or heteroaryl. Said compounds are inhibitors of poly(ADP-ribose) polymerase (PARP), and may be used for the treatment of a variety of disorders.
Patent IL-182575-A0 (IL)
Title: On-resin peptide cyclization
Filed: 2007-04-16
Abstract: A novel compound of formula I is devised.
Patent RO-125147-A0 (RO)
Title: Ceramic ring for cookers
Inventor: VASILE MARIN
IPC: A47J36/34
Filed: 2008-09-17
Abstract: The invention relates to a ceramic ring for cooker meant to equip cookers in order to reduce the methane gas consumption, while eliminating heat losses by radiation and reducing the heat losses by convection. According to the invention, the ring is made of glazed ceramic, it has circular shape, the diameter varying depending on the gas-ring size and it comprises a burning chamber (1), a separating wall (2), a support chamber (3) which carries out the sealing to the cooker, four channels (4) for fastening the pots and a circular orifice (5), cut in the upper part of the ceramic ring wall, wherethrough the exhaust gases are eliminated, the thickness of the ceramic ring wall varies depending on the diameter thereof.
Patent RO-125356-A0 (RO)
Title: Retractable () device
Inventor: CORBEANU DAN CONSTANTIN
IPC: B60B30/10
Filed: 2009-11-30
Abstract: The invention relates to a rolling device for displacing by pushing/pulling, preferably pieces of furniture or the like, for instance in a room or a hall. According to the invention, the device consists of a clamping plate (1) provided with some holes, to which there is undismountably mounted a nut (2) having a height of 20 mm, wherein there is threaded a height-adjusting screw (3), provided with a hole delimited by a profiled wall, protected by a profiled cover and wherein there is partially positioned a bolt (5) supporting a fork (6), in connection to which there is rotatably mounted a roll (7), by means of an axle (4), the screw (3) being provided with a channel wherein a safety ring (8) of the bolt (5) penetrates.
Patent RO-128413-A0 (RO)
Title: Power multiplier with pendulums in orbital rotation motion
Inventor: VLAD RAZVAN VICTOR
IPC: F16H25/06
Filed: 2012-11-14
Abstract: The invention relates to a power multiplier with pendulums in orbital rotation motion which efficiently uses the transfer of energy from it to energy-consuming technological equipments it can attend in various industrial fields. According to the invention, the multiplier comprises a shaft (1) which receives the rotational motion from a chain wheel (2) towards a central wheel (3), to some chain wheels (4), towards some toothed wheels (5) actuating some pendulum weights (6) so that the moment of resistance is compensated by the moment generated by the movement of some rods (7) which, by their tendency to permanently return to their initial position when the system is in static balance, cumulate the angular speed of the toothed wheels of the mechanism to the angular speed of an arm (8) by transfer ratios.
Patent AP-2002002557-A0 (AP)
Title: Method to present the threat situation on a display.
Inventor: ROLDAN PRADO ROBERTO
IPC: G06T11/20
Filed: 2000-11-25
Abstract: Method to present on a display at least one threat (tsf, tsf)between at least one pair of objects, (fiobj, seobj); characterlised by that only one threat cirlce, tc, is presented on the screen for all the first objects, fiobj, and all the second objects, seobj. The threats (tsf,tfs)are marked with symbols placed, in relation to the threat circle, in radial direction from the centre of the threat circle, tc, to respective second object, seobj, and /or first object, fiobj. The threat circle marks the boundary between the area nside the threat circle in which the threat does not exist. The radial distance of the threat symbol, to the threat circle, constitute a measure, in suitable threat scale (time, lenghth, etc.), of closeness to this transition.
Patent MC-1585-A1 (MC)
Inventor: SMITH KENDALL
IPC: A61K31/66
Filed: 1982-02-12
Abstract: Combinations of 9-[[2-hydroxy-1-(hydroxymethyl)-ethoxy] methyl]guanine and at least one other antivirally active drug such as phosphonoacetic acid and its salts, phosphonoformic acid and its salts, acycloguanosine, or a 5-(2-halogenovinyl)-2'-deoxyuridine show synergy in their activity against various herpesvirus infections including HSV-1 and HSV-2.
Patent IE-910941-A1 (IE)
Title: Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same
Inventor: DELANEY NORMA G
IPC: A61K31/195
Filed: 1991-03-21
Abstract: In accordance with the present invention, novel neutral endopeptidase inhibitors and methods for their use are disclosed. Compounds of the present invention, useful, for example, as cardio-vascular agents, have the general formula <CHEM>   <CHEM> phenyl substituted with alkyl of 1 to 4 carbons, alkoxy of 1 to 4 carbons, alkylthio of 1 to 4 carbons, hydroxy, halo, nitro or trifluoromethyl, or a heterocyclic group selected from thiazolyl, 4,5-dihydrothiazolyl, pyridyl, oxazolyl, isoxazolyl, imidazolyl, tetrazolyl, benzimidazolyl, benzothiazolyl or benzoxazolyl including substituted heterocyclic groups wherein the substituents are selected from halo, alkyl and phenyl; <IMAGE> and wherein the various groups are as defined herein.p
Patent IT-9000311-A1 (IT)
Inventor: MASSOCCO GIORGIO
IPC: B65G17/08
Filed: 1990-08-02
Abstract: PCT No. PCT/IT91/00069 Sec. 371 Date Apr. 2, 1992 Sec. 102(e) Date Apr. 2, 1992 PCT Filed Aug. 1, 1991 PCT Pub. No. WO92/02440 PCT Pub. Date Feb. 20, 1992.Equipment for continuously moving heavy loads in a generally horizontal plane comprising a support structure, cog-wheels carried on the support structure and base elements linked to one another by hinges carried on the cog-wheels and defining a chain. Support and moving wheels support the chain and slide on a slide surface. The cog-wheels have external teeth or projections which cooperate with slots in the support and moving wheels. The load carried by the top surface of the base elements is transferred to the support and moving wheels and then to the support structure. The equipment allows for movement of heavy loads in a generally horizontal plane.
Patent MA-20219-A1 (MA)
Inventor: ANDERS JUEL
IPC: B65D88/16
Filed: 1984-08-31
Abstract: A flexible container for filling, transport and storage of bulk material is made from at least one piece of base material. The bottom of the container is formed from at least four paired, preferably equally large, flaps which are direct extensions of the container side walls. The bottom flaps are formed by cut lines in the piece of material, and the angles  alpha  and  beta  of alternate flaps converge toward the center of the bottom. The sum of top angles alpha  and  beta  of the flaps is less than 360 DEG , such that the container bottom formed by joints of the flaps is downward slightly cone or funnel shaped when the container is filled. The sum of the angles  alpha  and  beta  of the flaps preferably is between (240 DEG -280 DEG ) and 360 DEG . The container bottom will be substantially square or rectangular, depending on whether  alpha = beta  or  alpha NOTEQUAL  beta . Each of the bottom seams can terminate at a distance from the center of the bottom such that there are no seams in a minor area around the center, and in this area there can be arranged a discharge spout.
Patent MA-22458-A1 (MA)
Inventor: CHOCHOY G
IPC: B29C48/06
Filed: 1992-03-09
Abstract: According to the invention, the writing or colouring pencil is obtained by triple extrusion of three thermoplastic materials forming the "lead" material (1), the expanded "wood" material (3) and an intermediate protective layer (2) which is free of expanding agent, is compatible with the "lead" material (1) and the "wood" material (3) and has a melting point which is equal to or greater than the melting point of the "lead" material and that of the "wood" material.   The three coextruded materials all contain, especially the same base component, for example a polystyrene-methacrylate copolymer. The protective layer (2) can be a different colour from the other two layers. The writing or colouring pencil with protective sheath between the "lead" and the expanded "wood", all three made from thermoplastic material, is particularly a pencil having a soft or extra-soft lead. <IMAGE>
Patent MA-23317-A1 (MA)
Inventor: JAMES R OLIFF
IPC: B65D5/54
Filed: 1994-08-31
Abstract: A package for beverage containers such as cans arranged in two or more axially-stacked tiers includes a carton having interconnected top, bottom and side walls. End closure structure connected to at least some of the walls closes one end of the carton. A dispenser for the containers includes first and second apertures defined in the end closure structure. The first aperture extends from one of the side walls and the bottom wall into the end closure structure, and the second aperture extends from the same side wall and the top wall into the end closure structure. The first and second apertures terminate remote from each other such that a portion of the end closure structure extends between the apertures and is connected to the side wall.
Patent MA-25591-A1 (MA)
Title: Enveloppe d'emballage
Inventor: DEALMANS EDDY
IPC: B65D75/14
Filed: 1999-09-27
Abstract: L'ENVELOPPE EST CONSTITUÉ D'UN FILM SECTIONNALE EN PELLICULES SÉPARÉS DESTINÉES à CONDITIONNER UN ARTICLE,  EN PARTICULIER UN PRODUIT ALIMENTAIRE,  ET à eTRE FERMÉES PAR PLIAGE DE LA PELLICULE AUTOUR DE CETTE ARTICLE.  POUR FACILITER LA CHOIX DU MATÉRIAUDU FILM SANS TENIR COMPTE DE CES PROPRIÉTÉS DE RETENTION DES PLIS,  LE FILM COMPORTE,  SUR CHAQUE PELLICULE,  AU MOINS UNE BANDE D'ENDUIT DE SCELLAGE à FROID à ADHÉRENTE CONTRôLÉE,  ASSURANT LE MAINTIEN DES PLIS ET LA FERMETURE DE L'EMBALLAGE,  APRèS LES PHASES DE PLIAGE DE LA PELLICULE AUTOUR DE L'ARTICLE à EMBALLER.
Patent MA-62717-A1 (MA)
Title: Préparation alimentaire expansée à base de lait, son procédé d'obtention et ses utilisations
Inventor: THOMAZO JEAN-BAPTISTE
IPC: A23C9/152
Filed: 2022-04-15
Abstract: La présente invention se rapporte à un nouveau produit alimentaire sec de type snack de lait expansé; elle se rapporte encore à son procédé de préparation et à ses utilisations.
Patent UY-25116-A1 (UY)
Title: Derivados de 1, 2, 4-triazolo [4, 3-b]-pirido [3, 2-d]- piridazina y composiciones farmacéuticas que los contienen
Filed: 1998-07-29
Abstract: Inhibidores de la fosfodiesterasa 4, consistentes en un principio activo constituído por 3 heterociclos condensados entre sí, que contienen en total 5 átomos de nitrógeno. Se incluyen procedimientos para su preparación.
Patent UY-27973-A1 (UY)
Title: Debencenoxazepinas
Inventor: SCHLEMMER DR KARL-HEINZ
IPC: C07D413/06
Filed: 2003-09-11
Abstract: La presente invención se refiere a compuestos, procedimientos para su preparación, composiciones farmacéuticas que los comprenden así como a su empleo en el tratamiento y/o profilaxis de enfermedades en humanos o animales, en especial de enfermedades cardiocirculatorias, por ejemplo la ateroesclerosis.
Patent UY-29060-A1 (UY)
Title: Solución para infusión de dihidropteridinonas estabilizada para el almacenamiento
Inventor: VEIT CLAUS
IPC: A61K31/395
Filed: 2005-08-12
Abstract: La presente invención se refiere a soluciones acuosas para infusión, o bien, inyección estabilizadas para el almacenamiento que contienen un principio activo de Fórmula general (I) donde los radicales L, R1, R2, R3, R4 y R5 presentan los significados indicados en las reivindicaciones y en la descripción, y una cantidad suficiente de un ácido o una mezcla de ácidos fisiológicamente compatibles para la disolución del principio activo y para la estabilización, así como eventualmente otros adyuvantes de formulación adecuados para uso parenteral, así como un procedimiento para preparar las soluciones para infusión, o bien, inyección según la invención.
Patent UY-30300-A1 (UY)
Title: Compuestos triarílicos y sus derivados
Inventor: HO CHIN YUNG
IPC: A61P25/28
Filed: 2007-04-20
Abstract: La presente invención se relaciona con compuestos que tienen la fórmula general (I) con compuestos que tienen la fórmula general (I) con las definiciones de X, Y, R1, R2, R3, R4, R9, R10 dadas a continuación y sus solvatos, hidratos, ésteres y sales farmacéuticamente aceptables. Más aún, la invención se relaciona con el uso de dichos compuestos para el tratamiento de la enfermedad de Alzheimer y con su uso para la modulación de la actividad y-secretasa-
Patent UY-30875-A1 (UY)
Title: Derivados de pirrolopiridina-2-carboxamidas, su preparacion y su aplicacion en terapéutica
Inventor: ANDRE MALANDA
IPC: A61K31/437
Filed: 2008-01-18
Abstract: La invencion se refiere a compuestos derivados de pirrolopiridina-2-carboxamidas de la formula general (I), en estado de base o de sal de adicion a un ácido, así como en estado de hidrato o de solvato donde los sustituyentes son tales como se han especificado en la memoria descriptiva y en las reivindicaciones. Se divulgan procedimientos de preparacion. Los compuestos presentan una actividad antagonista in vitro e in vivo para los receptores de tipo TRPV1 (o VR1) y son utiles en terapéutica.
Patent ES-177982-A1 (ES)
Title: Un dispositivo para poner fuera de circuito lamparas electricas en serie
Filed: 1947-05-10
Abstract: Dispositivo de puesta fuera de circuito de una lampara montada en serie con otras cuando se rompe o sufre un accidente su filamento; compuesto de un conductor revestido en una parte de su superficie de una delgada capa aisladora resistente a la tensión normal de funcionamiento ~ de la lámpara pero que salta bajo la tensión de servicio en los bornes del conjunto de las lámparas en serie siendo este conductor mantenido por dos pinzas metálicas sujetas por una parte a la porción inferior de los conductores de corriente en íntima vecindad con el pie y por otra parte a dicho conductor dejando una pequeña distancia entre sus sujeciones en dicho conductor.
Patent ES-180435-A1 (ES)
Title: Perfeccionamientos introducidos en el mecanismo de los calendarios de mesa y similares
Filed: 1947-11-10
Abstract: Perfeccionamientos introducidos en el mecanismo de los calendarios de mesa y similares, caracterizados porque los extremos de un sistema de brazos basculantes, suspendidos de un eje acoplado a unos soportes-escuadra, sirven de apoyo a unas chapas rígidas y de menos dimensión que las hojas del block que descargan sobre ella y que son mantenidas constantemente en un mismo nivel, cuando realizan las citadas chapas movimientos ascendentes, al discurrir mediante orificios laterales sobre los vástagos de dos horquillas cuyos extremos en forma de clavija, van alojados en unos taladros situados en el chasis.
Patent ES-180687-A1 (ES)
Title: UNA MáQUINA PARA RAYAR CRISTALES
Filed: 1947-11-27
Abstract: Una máquina para rayar cristales que esencialmente está constituida por una base que soporta dos carriles sobre los que va montado un carro con bastidor en el que se aprisiona en cristal que se ha de trabajar, el cual es rayado al ponerse en contacto con el filo de una piedra de esmeril en movimiento situada bajo dicho cristal a la parte que el carro se desliza sobre los carriles.
Patent ES-183398-A1 (ES)
Title: Un receptor superregenerativo
IPC: H03D11/02
Filed: 1948-04-21
Abstract: Receptor superregenerativo, caracterizado por medios para controlar una o más características operativas del receptor por ajuste de una o más características de la tensión interruptora.
Patent ES-186654-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA FABRICACIoN DE DERIVADOS DE BIGUADINA
IPC: C07C279/26
Filed: 1949-01-17
Abstract: Procedimiento para la fabricación de derivados de biguanida de la fórmula **(ver fórmula)** en la que R representa hidrógeno o un radical alquílico de reducido peso molecular R" representa hidrógeno o un radical alquílico de reducido peso molecular R" representa un radical alquílico de reducido peso molecular A y B representan hidrógeno o radicales alquílicos de reducido peso molecular siempre que ambos no representen radicales alquílicos de reducido peso molecular en uno y mismo producto X representa halógeno y representa hidrógeno halógeno o un radical alquílico de reducido peso molecular o un radical alcóxico de reducido peso molecular y Z representa hidrógeno o halógeno caracterizándose porque en primer lugar se hace reaccionar un halogenuro aminomagnésico de la fórmula **(ver fórmula)** o de la fórmula **(ver fórmula)** con una diciandiamida sustituida respectivamente de la fórmula **(ver fórmula)** o de la fórmula **(ver fórmula)** teniendo en todas estas fórmulas los caracteres A B X Y y Z R R' Y R" el mismo significado anteriormente citado y tratando después el producto de reacción con un ácido.
Patent ES-190607-A1 (ES)
Title: PROCEDIMIENTO PARA LA PREPARACIoN DE LOS ÉSTERES DEL áCIDO ALFA-AMINO-BETA-HIDROXI-FENILPROPIoNICO (FENILSERINA Y SUS DERIVADOS N-ACiLICOS Y N O-ACiLICOS, A PARTIR DEL áCIDO ALFA-AMINO-BETA-HIDROXI-FENILPROPIoNICO
Filed: 1949-11-29
Abstract: Procedimiento para la preparación de los esteres de la fenilserina caracterizado porque la fenilserina se esterifica en el alcohol adecuado mediante acción del ácido clorhídrico gaseoso al punto de ebullición del alcohol.
Patent ES-196379-A1 (ES)
Title: PROCEDIMIENTO PARA LA OBTENCIoN DE OXICETONAS
Filed: 1951-02-02
Abstract: Procedimiento para la obtención de oxicetonas de la serie de pregnano caracterizándose porque se trata un compuesto de pregnano que tenga la agrupación = CH-CH2/X en posición "17" representando en las misma "X" un oxi-grupo libre esterificado o esterizado con un óxido metálico susceptible de ser fijado sobre enlaces dobles de carbono-carbono y con un compuesto de peróxido obteniendo de la mezcla de reacción la 17 20-oxi-cetona así formada
Patent ES-290086-A1 (ES)
Title: Improvements in or relating to detecting apparatus
IPC: B25B11/00
Filed: 1963-07-17
Abstract: Apparatus for detecting the presence or absence of the surface of a toughened glass sheet or windshield comprises inner and outer tubes 1, 2 defining an annular nozzle 3. Fluid under pressure is forced radially into the space between tubes 1, 2 by a pump 15 (Fig. 3, not shown) and the back pressure in tube 1, which varies with the position of the surface, is measured by a pressure sensitive device 16, e.g. a pressure switch, a pressure transducer or a manometer. The apparatus shown in Fig. 5 forms part of an apparatus for testing toughened glass 23 moving on a conveyer 21. The jet nozzle 26 of the device detects the leading and trailing ends of a sheet of glass 23, the change in pressure operating a pressure switch 30 with a central contact arms 31. A control device comprising a uniselector 32 responsive to the pressure switch 30 and connected to pulse generating means comprising an eccentric cam 33 driven at a speed proportional to the conveyer 21 carrying the sheet 23, controls a percussion impact means 25 and causes it to subject the central part of the glass sheet 23 to an impact to test that it has been sufficiently toughened. <PICT:1029826/C1/1> <PICT:1029826/C1/2>
Patent ES-313466-A1 (ES)
Title: Improvements in diesel rotary-piston engines
IPC: F02B3/06
Filed: 1965-05-28
Abstract: A rotary-piston diesel engine of the kind comprising an n-lobed piston 3, Fig. 1, of epicycloidal contour eccentrically revolving in a stator having n + 1 lobes to provide n + 1 working chambers, includes with each working chamber a cylindrical cross-section combustion chamber 9 extending the full axial length of the piston, an air inlet valve 18 and an exhaust valve 19. As the piston 3 rotates in the direction of the arrow 4, the centre of gravity of the volume of each working chamber moves in the direction of the arrows 7 so that during one revolution of the piston this centre of gravity moves in the direction of the arrow 8 opposite to that of piston rotation to create a two-dimensional turbulence throughout the entire length of the working chamber. At the same time air in the combustion chamber rotates in the direction of the arrow 11 opposite to the direction 8 to create further turbulence. The inlet duct 21 controlled by the valve 18 is positioned with its axial plane coincident with the mid transverse plane of the piston at a small angle to the working chamber so that the air is directed into the working chamber perpendicular to the engine axis in a direction opposite to that of piston rotation to create still further turbulence. Fuel injectors, one or two, are mounted for symmetrical injection of fuel into each combustion chamber. A starting glow-plug is fitted in each combustion chamber. To preserve a high operating temperature the combustion chamber may be fitted with a liner which except for a small distance adjacent the mouth of the chamber is free from contact with the surface of the chamber. Bolts connecting the end portions of the stator to the central portion may be regularly spaced around the stator close to its curved contour to provide effective gas-tight seals. The combustion chamber may be located upstream of, downstream of or between the valves 18, 19.
Patent ES-342458-A1 (ES)
Title: Hair drier
IPC: A45D20/22
Filed: 1967-06-30
Abstract: A hair drier comprises a motor and fan unit 20 for supplying air to the hair via a delivery duct 24 and perforations 4 in the inner wall of a double walled hood 1, the motor and fan unit being situated at the back of the hood and comprising a pair of centrifugal fans (22, 23) carried on the opposite ends of the shaft of a single motor, there being a manifold 61 extending substantially the whole way round the periphery of the hood so that it may draw in air after it has impinged on the hair and providing, with suction ducts 60, the sole path for the supply of air to the fan inlets. The hood 1 may be of a transparent thermoplastic material and may be contained with the motor and fan unit 20 within a casing 31 adjustably mounted on a pillar support (14). There may be two separate delivery ducts (24, 25, Figure 3, not shown) or two interconnected ducts (24, 25, Figure 4, not shown). The motor may be provided with a time switch, a heater (26, 27, or 52) in the delivery duct may be provided with an automatic temperature control of exemplified type, and the perforations 4 in the inner wall of the hood may be non-uniformly distributed and may be shaped as nozzles. There may be a valved extractor opening from the delivery ducts to atmosphere so that fresh air is drawn into the drier at the manifolding 61. In an embodiment (Figures 1-3, not shown) the suction ducts for returning air to the motor and fan unit are formed by spaces between the casings 31, the outer wall of the hood, and the delivery ducts.
Patent ES-346125-A1 (ES)
Title: Substituted thiocyano pyrroles,fungicidal preparations containing these compounds as active ingredients and methods of using the same
IPC: C07D207/36
Filed: 1968-10-16
Abstract: Pharmaceuticals, fungicides and antiseptics comprise novel oompaunds of the general formula:- in which R 1 is H, a straight, branched or cyclic hydrocarbon chain with possibly an amino group or a halogen group, an ester "or a hydroxyalkyl group, R 2 and R 5 both or one of the two is a thiocyano group and the other a hydrogen atom or an acyl group and R 3 and R 4 are selected from hydroxy alkyl groups, hydrogen atoms or alkyl groups, their salts, or mixtures alone or with a solid or liquid inert carrier material or excipients and if desired surface active agents and/or dispersing agents or together with a therapeutically acceptable carrier. The compounds are made by reacting substituted pyrroles with thiocyanogen. (see Division C2).