Patent GB-1104367-A (GB)
Title: Control of biological problems in paper-mill systems
IPC: A01N47/48
Filed: 1965-07-19
Abstract: Biocides are tested as follows:  The culture medium comprises dextrose, a protein hydrolysate and water and is sterilized. This is inoculated with a broth culture of A. aerogenes or a spore suspension of A. niger, and placed in each of a series of fermentation tubes with caps, each tube containing the test chemical.  The chemical and inoculated medium are mixed gently.  Two controls are run, chemical being omitted from one, and inoculum from the other.  In the case of A. aerogenes, the tube is inverted to fill the gas-detection vials, incubated for 48 hours at 98 DEG F. and the presence or absence of gas production noted.  In the case of A. niger, the tubes are shaken and incubated for 5 days at 86 DEG F.  The presence or absence of growth in the tubes is noted.  In another test, similarly inoculated media after 1 or 24 hours contact with the chemicals are diluted 1000-fold, introduced into sterile culture tubes, incubated for 48-72 hours at 30 DEG C. and examined for growth.ALSO:Biological problems in the pulp-preparation and recovery and wet-end systems of paper-making operations are prevented or mitigated by treating the systems concurrently with methylene bis-thiocyanate and at least one other bactericide or fungicide. When one part of the system is contaminated predominantly with bacteria, that part is treated with methylene bisthiocyanate and the other part with a halogenated ketone, a halogenated ester, 3,5-dimethyl-tetrahydro-1,3,5,2H-thiadiazine-2 -thione, a halogen or a halogen-releasing compound, e.g. a chlorite or hypochlorite, a halogenated alkene, an amine or polyamine, a quaternary ammonium salt, a thiocarbamate, an aldehyde or a sulphone.  When one part is contaminated predominantly with yeasts, that part is treated with methylene bisthiocyanate and the other part with a halogenated phenol or an alkali-metal salt thereof.  When one part of the system is contaminated predominantly with bacteria and the other with yeasts, they may be treated with methylene bisthiocyanate and a halogenated phenol or alkali-metal salt thereof respectively.  When the system is contaminated with both bacteria and yeast, the treatment may be alternately with methylene bisthiocyanate and with one of the bactericides listed above for bacterial contamination.  The bactericide may be used in conjunction with a dispersant, e.g. a sulphonated lignin, a nonylphenol reacted with ethylene oxide or a fatty alcohol (e.g. lauryl) reacted with ethylene oxide.  Exemplary compositions p  comprise: (A) methyl ethers of mono-, di-and tri-propylene glycol, pentachlorophenol, trichlorophenol, Stoddard solvent, polyoxyethylene ether surface-active agent, water and potassium hydroxide; (B) sodium carbonate, sodium chloride, tetrasodium pyrophosphate, sodium salt of 2,4,5-trichlorophenol, oxidized starch, sodium hydroxide and water; (C) 3,5-dimethyltetrahydro-1,3,5,- 2H-thiadiazine-2-thione, sodium hydroxide, isopropanol, 2-mercaptobenzothiazole, sodium lignosulphonate, glyconic acid and water; and (D) propylene glycol, bromo-acetic acid, toluenesulphonic acid and a polyalkoxylated aliphatic base.ALSO:Biological problems in the pulp-preparation and recovery and wet-end systems of paper-making operations are prevented or mitigated by treating the systems concurrently with methylene bis-thiocyanate and at least one other bactericide or fungicide. When one part of the system is contaminated predominatly with bacteria, that part is treated with methylene bisthiocyanate and the other part with a halogenated ketone, a halogenated ester, 3,5-dimethyl - tetrahydro - 1,3,5,2H - thiadiazine - 2 - thione, a halogen or a halogen-releasing compound, e.g. a chlorite or hypochlorite, a halogenated alkene, an amine or polyamine, a quaternary ammonium salt, a thiocarbamate, an aldehyde or a sulphone.  When one part is contaminated predominantly with yeasts, that part is treated with methylene bisthiocyanate and the other part with a halogenated phenol or an alkali-metal salt thereof.  When one part of the system is contaminated predominantly with bacteria and the other with yeasts, they may be treated with methylene bisthiocyanate and a halogenated phenol or alkali-metal salt thereof respectively.  When the system is contaminated with both bacteria and yeast, the treatment may be alternately with methylene bisthiocyanate and with one of the bactericides listed above for bacterial contamination.  The bactericide may be used in conjunction with a dispersant, e.g. a sulphonated lignin, a nonylphenol reacted with ethylene oxide or a fatty alcohol (e.g. lauryl) reacted with ethylene oxide. Exemplary compositions comprise: (A) methyl ethers of mono-, di- and tri-propylene glycol, pentachlorophenol, tri-chlorophenol, Stoddard solvent, polyoxyethylene ether surface-active agent, water and potassium hydroxide; (B) sodium carbonate, sodium chloride, tetrasodium pyrophosphate, sodium salt of 2,4,5-trichlorophenol, oxidized starch, sodium hydroxide and water; (C) 3,5-dimethyltetrahydro - 1,3,5 - 2H - thiadiazine - 2-thione, sodium hydroxide, isopropanol, 2-mercaptobenzothiazole, sodium lignosulphonate gluconic acid and water; and (D) propylene glycol, bromo-acetic acid, toluenesulphonic acid and a polyalkoxylated aliphatic base.