baber/WOPTO huggingface dataset:
Patent CA-2108144-A1 (CA)
Title: Methods and compositions for the selective inhibition of gene expression
Inventor: ROTH JACK A
IPC: A61K48/00
Filed: 1992-03-06
Abstract: Disclosed are methods and compositions for the selective inhibition gene expression through the application of antisense RNA  technology. Antisense RNA constructs of the present invention employ the use of antisense intron DNA corresponding to distinct intron regions of the gene whose expression is targeted for down-regulation. In an exemplary embodiment, a human lung cancer cell line (NCI-H460a) with a homozygous spontaneous K-ras mutation was transfected with a recombinant plasmid that synthesizes a genomic segment of K-ras in antisense orientation. Translation of the mutated K-ras mRNA was specifically inhibited, whereas expression of H-ras and N-ras was unchanged. A three-fold growth inhibition occurred in H460a cells when expression of the mutated ras p21 protein was down-regulated by antisense RNA and cells remained viable. The growth of H460a tumors in nu/nu mice was substantially reduced by expressed K-ras antisense RNA.
Patent CA-2108373-A1 (CA)
Title: Secondary sewage treatment system
Inventor: STUTH WILLIAM L
IPC: C02F3/22
Filed: 1991-05-29
Abstract: A secondary sewage treatment system is provided with vertically-aligned foam collecting (13), turbulent (12), mixing (11), settling (10), and sludge collecting (9) zones. A grating (7) defines the boundary between the turbulent and mixing zones. Beneath the grating (7), a buoyant media (17), such as hollow plastic spheres, are contained and occupy substantially all of the mixing zone. Air diffusers (18) including elongated draft tubes (8) extend from the turbulent zone (12) down through the mixing zone (11) for introduction of air to aerate waste water liquor and to cause the aerated liquor to recirculate up into the turbulent zone, thereby creating a circulation of waste water liquor from the turbulent zone, down through the mixing zone and around the buoyant media, and up through the draft tubes to the turbulent zone.
Patent CA-2109511-A1 (CA)
Inventor: BASSERES ANNE
IPC: C09D105/04
Filed: 1993-03-09
Abstract: 2109511 9318109 Protection des surfaces solides et particulièrement les zones littorales contre la pollution par hydrocarbures, par application d'une couche protectrice composée de polysaccharides renfermant des groupes carboxyl libres, commes les alginates ou les pectines faiblement méthylées.
Patent CA-2112562-A1 (CA)
Title: Platelet activating factor antagonists
Inventor: SUMMERS JAMES B
IPC: A61P7/06
Filed: 1992-07-14
Abstract: Indole compounds substituted at the 3-position by a 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]thiazole, 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]oxazoline, or 7-carbonyl(pyridin-3-yl)pyrrolo[1,2-c]pyrrole group are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
Patent CA-2114229-A1 (CA)
Title: Electrophoretic Display Panel with Interleaved Local Anode
Inventor: DISANTO FRANK J
IPC: G02F1/167
Filed: 1992-08-17
Abstract: An improvement to an electrophoretic display having a cathode/grid/local anode matrix (18, 20, 28) and a remote anode (26) and to the method for making the display includes forming the local anode lines (28) in the same plane as the grid lines (20) from the same material and in the same fabricating step. The local anode lines (28) are insulated from the grid lines (20) and are interleaved therewith, each being formed on a common layer of photoresist. It is preferred that each grid line be associated with one local anode line, that the grid lines (20) have lines (30) and that the local anode lines (28) be disposed between the tines (30).
Patent CA-2116306-A1 (CA)
Inventor: FRIOT LAURENT
IPC: B61D27/00
Filed: 1994-02-23
Abstract: DISPOSITIF DE REGULATION DE CLIMATISATION L'invention concerne un dispositif de régulation de climatisation d'un local fixe ou en mouvement, le local étant climatisé grâce à une unité de conditionnement commandée par un correcteur recevant sur ses entrées une grandeur de consigne de température (Tc) et une grandeur représentative de la température du local, caractérisé en ce que le dispositif comprend un organe de simulation nonlinéaire et non-stationnaire de l'ensemble constitué par l'unité de conditionnement et par le local et en ce que le correcteur comprend des moyens de gestion (26-28) de la saturation de manière à prendre en compte une limitation de l'amplitude du signal de commande du processus (12) et du modèle (13) du processus. Application notamment à la régulation de climatisation de véhicules ferroviaires. Figure à publier : Fig. 6
Patent CA-2116838-A1 (CA)
Title: Method and Apparatus for Treating and Packaging Raw Meat
Inventor: MORGAN ARTHUR I JR
IPC: A23B4/24
Filed: 1994-03-02
Abstract: A method and apparatus for killing microorganisms on the surface of raw meat.  The microorganisms are killed by exposing the meat to controlled applications of a biocidal treatment gas in a vacuum/pressure regulated environment.  The meat is first exposed to a vacuum, the surface then flushed with an air-free treatment gas, then full treated with the air-free treatment gas, and then reexposed to a vacuum.  The method and apparatus successfully kills microorganisms on the surface and pores of raw meat without causing significant deleterious changes to the meat.
Patent CA-2117538-A1 (CA)
Title: Process for the preparation of clavulanic acid
Inventor: COOK MICHAEL ALLEN
IPC: A61K35/00
Filed: 1993-06-07
Abstract: A process for the preparation of clavulanic acid or its pharmaceutically acceptable salts and esters in which an amine of formula (II) is used as an intermediate to form a salt with clavulanic acid, R1, R2 and R3 being selected from various substituent atoms and groups.
Patent CA-2121038-A1 (CA)
Title: Oral preparation for release in lower digestive tracts
Inventor: YAMADA AKIYA
IPC: A61K9/52
Filed: 1992-08-13
Abstract: An oral pharmaceutical preparation of a type released at infragastrointestinal tract was successfully prepared, wherein a solid organic acid dissolvable, in the form of a solution, of chitosan and a solid pharmaceutical preparation including a principal agent are filled in a hard capsule composed of the base principally comprising chitosan and an enteric coating is formed on the surface of the hard capsule, characterized in that a desirable releasing time can be arranged, with no pH dependency, via water permeability derived from the porosity of chitosan of the capsule preparation.
Patent CA-2122455-A1 (CA)
Inventor: PHILLIPS GERALD W
IPC: A61K31/34
Filed: 1992-11-09
Abstract: Disclosed is a continuous process for the manufacture of 2,5-dihydrofurans by the isomerization of .gamma.,.delta.-epoxyalkenes in the liquid phase in the presence of a catalyst system comprising an onium iodide compound and a Lewis acid and a process solvent comprising a mixture of the 2,5-dihydrofuran product of the process and an oligomer of the .gamma.,.delta.-epoxyalkenes reactant.
Patent CA-2125519-A1 (CA)
Inventor: BERGSTEN VICTOR E
IPC: F17C3/04
Filed: 1994-06-09
Abstract: A low heat-leak cryogenic system comprising a cryogenic fluid, a first lamina having an external side facing toward and exposed directly to, or indirectly to, the cryogenic fluid and an internal side facing away from the cryogenic fluid; a second lamina spaced apart from the first lamina, and at least one block or layer of coherent aerogel extending from the first lamina to the second lamina.  In another version, the aerogel is in a gaseous environment having a pressure not greater than 250,000 micrometers of mercury.  In another version, at least one of the lamina is flexible so as to at least partially transmit an external load, such as that imposed by the atmosphere, to the coherent aerogel, and the coherent+ aerogel is capable of at least partially transmitting a load imposed on it from one lamina to the other.
Patent CA-2126927-A1 (CA)
Inventor: MAITRA SIDHARTHA
IPC: G10L19/04
Filed: 1994-06-28
Abstract: The voice over data component of a personal communications system enables the operator to simultaneously transmit voice and data communication to a remote site.  This voice over data function directly encodes digitized voice samples onto the carrier using quadrature amplitude modulation to transmit multiple bits of the voice sample for every baud.  The system also allocates selected bauds of the carrier to voice and to data so the voice over data may be transmitted using the same allocated bandwidth. The system may also dynamically reallocate the bandwidth over the telephone line depending on the demands of the voice grade digitized signal.
Patent CA-2129168-A1 (CA)
Inventor: VINCI JAMES N
IPC: C10M163/00
Filed: 1994-07-29
Abstract: Abstract of the Disclosure This invention relates to a lubricating composition comprising a major amount of an oil of lubricating viscosity, (A) at least one dithiocarbamate compound, and (B) at least one organic polysulfide. The invention also relates to greases and aqueous compositions which contain this combination. The compositions have good antiwearor extreme pressure properties. The combination also provides improved oxidationresistance and thermal stability to fluids.
Patent CA-2129757-A1 (CA)
Title: High performance acoustical cleaning apparatus for teeth
Inventor: GIULIANI DAVID
IPC: A61C17/22
Filed: 1993-02-05
Abstract: The dental hygiene apparatus includes a body portion (12) from one end of which extends an elongated resonator arm (32). The arm (32) is mounted for oscillating action about a torsion pin (38), by means of an electromagnet (t6) in the body acting in combination with two permanent magnets (34, 35) which are mounted on the rear end (31) of the resonator arm (32). On the forward end (44) of the resonator arm (32) is mounted a set of bristles (47). The arm (32) is driven such that the tips of the bristles operate within ranges of amplitude and frequency to produce a bristle tip velocity greater than 1.5 meters per second, producing a significant cleansing effect beyond the tips of the bristles.
Patent CA-2129959-A1 (CA)
Title: Injectable preparations for curing affected abnormal tissues, method for the preparation thereof, and usage thereof
Inventor: OKAZAKI HIDEO
IPC: A61K33/10
Filed: 1993-09-20
Abstract: An injectable preparation for curing affected abnormal tissues contains a composition having a water-soluble aluminium compound in a concentration ranging from 0.01 mole to 0.5 mole, tannic acid at a rate of 0.5% to 25.0% with respect to said water-soluble aluminium compound, and sodium hydrogen sulfite, and having a pH ranging from pH1.5 to pH3.5. The injectable preparation is extremely stable even during storage for a long period of time and causes neither coloring nor depositing during storage. Further, the injectable preparation is remarkably effective for curing the affected abnormal tissues caused by, for example, brain aneurysm, hemorrhoids, hepatic tumor vessels and so on.
Patent CA-2130858-A1 (CA)
Title: Orbital Shaking Attachment
Inventor: FLETCHER DAVID J
IPC: B01F11/00
Filed: 1994-08-25
Abstract: An orbital shaking attachment can be fitted or removed from a magnetic stirrer thereby giving the stirrer the extra function of orbital shaking in addition to its primary function of magnetic stirring. The principal of he invention could also be used to make a dedicated orbital shaker for other applications such as in an over, incubator or liquid filled tank. The orbital shaking attachment includes a top-plate/platform with a circular magnet attached centrally to its underside and a base-plate with a central circular hole. The two plates are separated by ball bearings which are able to roll around orbitally in bearing cups on both plates. When operated the base-plate is static and the top-plate/platform moves orbitally. The device is constructed mainly from non-ferrous material except for the circular magnet and ball bearings.
Patent CA-2133756-A1 (CA)
Title: Treatment of Urological and Gastric Fluid Reflux Disorders by Injection of Micro Particles
Inventor: ERSEK ROBET A
IPC: A61L27/18
Filed: 1993-03-30
Abstract: Novel principles for treating urological and gastric fluid reflux disorders are disclosed involving the injection of textured micro particles (30) wherein the textured micro particles having a combination of average unidimensional particle size range and average particle texture cooperate substantially to prevent loss of the micro particles from any injection site (31).
Patent CA-2133994-A1 (CA)
Title: Nitric oxide sensor
Inventor: MALINSKI TADEUSZ
IPC: G01N33/00
Filed: 1993-04-16
Abstract: A nitric oxide (NO) microsensor (34) based on catalytic oxidation of NO comprises a thermally-sharpened carbon fiber with a tip diameter of about 0.5-0.7 µm coated with several layers of p-type semiconducting polymeric porphyrin and cationic exchanger deposited thereon. The microsensor (34) which can be operated in either the amperometric voltametric or coulometric mode utilizing a two or three electrode system, is characterized by a liner response up to about 300 µM, a response time better than 10 msec and a detection limit of about 10 nM. The sensor (34) of the present invention also discriminates against nitrite, the most problematic interferant in NO measurements. The amount of NO released from a single cell can thus be selectively measured in situ by a porphyrinic microsensor (34) of the invention. A larger scale sensor (12) utilizing porphyrin and cationic exchanger deposited on larger fibers or wires, platinum mesh or tin indium oxide layered on glass, can also be employed when measurement of NO  concentration in chemical media, tissue or cell culture is desired.
Patent CA-2136365-A1 (CA)
Inventor: ALLEN JONATHAN B
IPC: H04M1/00
Filed: 1994-11-22
Abstract: An automated method for modifying a speech signal communicated over a telephone network by applying a gain factor in a telephone set before any side tone is added thereto. The gain factor is a function of a received signal indicative of the background noise at the location of the telephone set. The gain applied may be a function of both the background noise level and the original speech signal. Either a linear or a non-linear (e.g., compressed) amplification of the original speech signal may be performed, where a compressed amplification results in the higher level portions of the speech signal being amplified by a smaller gain factor than lower level portions. The speech signal may be separated into a plurality of subbands, each resultant subband signal being individually modified in accordance with the present invention. In this case, each subband speech signal is amplified by a gain factor based on a corresponding subband noise signal, generated by separating the background noise signal into a corresponding plurality of subbands. The individual modified subband signals may then be combined to form the resultant modified speech signal.
Patent CA-2139051-A1 (CA)
Inventor: PANTEV GEORGE
IPC: F16B7/04
Filed: 1994-12-23
Abstract: A connector is provided for joining hollow, elongate frame members, such as tubes, to a support structure such as another tube.   The connector has a base portion with inner and outer faces,  the inner face being shaped to conform to the shape of the adjacent surface of the support structure.   The  connector has  at  least  one  spreading mechanism extending outwardly from the base portion and having external transverse dimensions enabling it to be inserted into an end of the elongate frame member.  This mechanism has  parallel  first  and  second  arms  located adjacent each other.  A screw is located in a threaded hole extending transversely through the first arm.  This screw can be used to push against the second arm and thereby spread the arms apart.  The base portion can have a hole formed therein to receive an elongate fastener used to connect  it  to the support  structure.   In a preferred embodiment, the second arm is divided into two parallel prongs separated by a narrow slit.
Patent CA-2141191-A1 (CA)
Inventor: BROCK THOMAS
IPC: C09D131/02
Filed: 1994-05-25
Abstract: Selon un procédé d'application de plusieurs couches de laque sur un substrat, on applique une couche de laque de fond constituée d'un enduit aqueux sur un substrat, le cas échéant, déjà enduit, puis on recouvre la couche de laque de fond d'une laque transparente qui contient: (A) au moins un copolymère contenant des groupes hydroxyles, préparé par réaction de (a) un ou plusieurs esters d'acides monocarboxyliques saturés, aliphatiques, ramifiés en  alpha  et ayant un ou plusieurs groupes époxyde ou liaisons doubles éthyléniques dans la partie alcool, avec (b) un ou plusieurs esters d'alkyle d'acides carboxyliques éthyléniquement  alpha , beta -insaturés, (d), le cas échéant, un ou plusieurs acides carboxyliques éthyléniquement  alpha , beta -insaturés, et (e), le cas échéant, un ou plusieurs monomères de vinyle différents de (a), (b), (c) et (d); (B) un ou plusieurs polyisocyanates présentant en moyenne au moins 1,5 groupes NCO dans la molécule, en une quantité telle que le rapport en équivalents entre les groupes OH du composant (A) et les groupes NCO du composant (B) soit compris entre 1:1,6 et 1:2,2.
Patent CA-2141236-A1 (CA)
Title: Saw guide for cutting truss joist i-beams
Inventor: EKKER SHAWN
IPC: B23Q9/00
Filed: 1995-01-27
Abstract: A guide for cutting a truss joist I-beam with a hand-held power saw such as a worm drive, hypoid drive, or circular saw is disclosed. The guide comprises a base positionable along a top surface and an inner edge of one chord of the I-beam, a mechanism mounted on the base for securely holding the base to the chord, and a cutting guide pivotally mounted on the base for guiding a hand-held power saw at a selected angle in cutting the I-beam. The holding mechanism includes a handle extending from the base and a pivot arm pivotally coupled to the base. The pivot arm has a gripping and for contacting the chord and a pivot handle for pulling upwardly toward the handle for causing the gripping end to pivot into contact with the chord. The cutting guide comprises a face plate having a flat bottom surface for bridging and resting upon the tops of the chords of the I-beam and a flat front surface generally perpendicular to the bottom surface of the face plate for guiding a side support edge of a hand-held power saw when cutting the I-beam, a shoe support mounted on and extending forwardly from the bridge plate having a flat top surface coplanar with the bottom surface of the bridge plate for guiding a lower support edge of the hand-held power saw, and a mechanism for setting the saw guide for cutting the I-beam at a selected angle.
Patent CA-2142056-A1 (CA)
Title: Automatic transmission fluids and additives therefor
Inventor: OHTANI HIROKO
IPC: F16H57/04
Filed: 1995-02-08
Abstract: An effective way is described for overcoming the shudder problem associated with continuous slip torque converter clutches for use in automatic transmissions, especially shudder which occurs with new friction materials before break-in. To do this, an ATF is used in which the friction modifier system consists essentially of (i) an N-aliphatic hydrocarbyl-substituted diethanoiamine in which the N-aliphatic hydrocarbyl-substituent is at least one straight chain aliphatic hydrocarbyl group free of acetylenic unsaturation and having in the range of 14 to 20 carbon atoms, and (ii) an N-aliphatic hydrocarbyl-substituted trimethylenediamine in which the N-aliphatic hydrocarbyl-substituent is at least one straight chain aliphatic hydrocarbyl group free of acetylenic unsaturation and having in the range of about 14 to about 20 carbon atoms. The ATF is devoid of any tertiary amine friction modifier component and any C12-36 aliphatic hydrocarbyl succinimide or succinamide friction modifier. Specified relative proportions and concentrations of (i) to (ii) are used.
Patent CA-2142395-A1 (CA)
Title: Method and device for feeding disc in autochanger
Inventor: CHO CHAN-KYOUNG
IPC: G11B17/22
Filed: 1995-02-13
Abstract: Method and device for feeding disc in an autochanger are disclosed.  The disc feeding method and device feed, using a simple disc feeding mechanism, the compact discs between the disc magazines and the compact disc players of the autochanger through a rolling type feeding motion.  Therefore, the discs are prevented from damage during the disc feeding operation.          In the disc feeding operation, the edge of the disc rolls along the guide rails so that it is possible to minimize the disc damage.  The device of the invention reduces the size and weight of the autochanger and achieves the recent trend of compactness of the autochanger.
Patent CA-2143865-A1 (CA)
Inventor: LEA ROGER W
IPC: B65B39/00
Filed: 1993-08-31
Abstract: A valve for use in a line for transporting slurry comprises a housing (1) defining a valve port through which slurry is to pass. The housing (1) is formed with a concave lower end (2) which forms the valve seat adjacent the valve port and a valve clo-sure member having an outer convex surface (5) complementary in shape to the concave surface of the valve seat is provided to close the valve. A float (7) is connected to the valve closure member (3) and is adapted to float on the surface of the slurry and open and close the valve in response to the slurry surface level. The valve closure member (3) has a sharpened and/or hardened edge to cut through solid matter in the slurry.
Patent CA-2144598-A1 (CA)
Title: Device and method for forming neat ends on frayable rope
Inventor: PARSONS LLEWELLYN BERTRAM
IPC: B25B5/00
Filed: 1995-03-14
Abstract: A generally cylindrical rope slide acts as a grip to hold a rope end while it is being heated to melt the end as a deterrent to fraying. The slide has a longitudinal slot so that it may be squeezed to grip the rope or relaxed to slide on the rope. The slide may cover the rope end during cooling to act as a mold. The slot widens at one end so that the rope may be wedged into the widened portion to force the slot open for insertion of a bight of rope.
Patent CA-2144604-A1 (CA)
Title: Apparatus for processing peripheral selvedges of fabric
Inventor: ETO HIROYUKI
IPC: D05B35/06
Filed: 1995-03-14
Abstract: Apparatus for processing peripheral selvedges of fabric comprises: a sewing machine unit for sewing up fabrics; an air table mechanism incorporating a number of jet apertures through which air is jetted onto upper surface of the table in the obliquely upward direction towards a product guide member; a supplementary roller unit vertically ascending and descending to shift a processable fabric synchronous with feeding amount of the sewing machine unit; a rotating unit having a fabric holding unit which descends only when sewing of fabric corner is executed in order to hold and rotate the objective fabric by a predetermined angle and then ascends after rotating the fabric by a predetermined angle; a flange supply unit for supplying flange to the sewing machine unit; and a controller unit for integrally controlling operation of the above component units, wherein the flange supply unit comprises a feed roller driven by a motor, a rotatable pressing roller perpendicularly rotating via a pneumatic cylinder, a cutter unit, and a pressing unit for pressing both sides of flange fed from the flange supply unit by way of centering around travelling line of the cutter.