baber/WOPTO huggingface dataset:
Patent AU-2003295366-B2 (AU)
Title: Synthetic muscle promoters with activities exceeding naturally occurring regulatory sequences in cardiac cells
Inventor: SCHWARTZ ROBERT J
IPC: C12N15/09
Filed: 2003-10-30
Granted: 2011-11-24
Abstract: Transgenes driven by naturally occurring cardiac promoters have relatively low levels of cardiac transgenic gene expression, and have consequently limited the use of cardiac muscle as a target for plasmid mediated gene supplementation. However, by randomly assembling motifs of E-box, MEF-2, TEF-1 and SRE elements, cardiac-specific synthetic promoter recombinant libraries have been produced. By screening hundreds of resultant clones for transcriptional activity both and , a few cardiac-specific synthetic promoters were discovered comprising a transcriptional potency that greatly exceeds the transcriptional levels obtained from natural myogenic and viral gene promoters. These promoters are used to direct the expression of desirable genes in nucleic acid expression constructs specifically to cardiac cells. Thus, these cardiac specific-synthetic promoters can be utilized for plasmid mediated gene supplementation for serious health conditions, such as ischemic disease, myocardial infarction or heart failure. Thus, one aspect of the current invention is a cardiac specific-synthetic promoter produced by a method that generates a library of randomized synthetic-promoter-recombinant expression constructs. Another aspect of the present invention is directed to a method using the cardiac specific-synthetic expression construct for expression a gene of interest in a cardiac cell.
Patent AU-2004277760-B2 (AU)
Title: System and method for imaging the reflectance of a substrate
Inventor: CAN INCE
IPC: A61B5/00
Filed: 2004-10-01
Granted: 2011-09-29
Abstract: The present application discloses a system and method for the comprehensive monitoring of the microcirculation in order to assess the ultimate efficacy of the cardiovascular system in delivering adequate amounts of oxygen to the organ cells. The system utilizes reflectance avoidance by reflectance filtering, such as OPS imaging or Mainstream Dark Field imaging, or by Sidestream Dark Field imaging, which utilizes external direct light on the tip of the light guide to achieve reflectance avoidance whereby incident and reflected light do not travel down the same pathway. The system can combine reflectance avoidance with other imaging modalities to provide information regarding perfusion, oxygen saturation and oxygen availability, The system can image the reflectance of a substrate and may include a light source, a light transport body configured to project light from the light source to an examination substrate and transmit light reflected by the examination substrate, and an analysis section in optical communication with the light transport body and having a reflectance avoidance imaging module and at least one of a reflectance spectrophotometry module and a fluorescence imaging module. The method may include utilizing the microcirculatory flow information, the oxygen availability information, and the adequacy of oxygenation of tissue cells information, making an early and sensitive determination regarding states of shock, such as septic, hypovolemic, cardiogenic and obstructive septic shock, in patients, and guiding resuscitation therapies aimed at correcting this condition.
Patent AU-2004302422-B2 (AU)
Title: Cell reselection method for receiving packet data in a mobile communication system supporting MBMS
Inventor: JEONG KYEONG-IN
IPC: H04B7/26
Filed: 2004-08-20
Granted: 2008-02-21
Abstract: A method for selecting a cell by a user equipment (UE) to receive a Multimedia Broadcast/Multicast Service (MBMS) service in a mobile communication system which supports the MBMS service with different frequency allocations (FAs) in the same area. In the method, a radio network controller (RNC) transmits information on an MBMS cell to the UE, and the MBMS cell information includes an MBMS offset for guaranteeing priority for cell reselection to the MBMS cell. The UE performs cell reselection using the MBMS cell information and receives the MBMS service from the reselected cell.
Patent AU-2005231223-B2 (AU)
Title: Clamping apparatus, drill string component and rock drilling rig
Inventor: KAMPE ULF
IPC: E21B/
Filed: 2005-02-28
Granted: 2010-02-11
Abstract: The present invention relates to a clamping apparatus for use with a rock drilling rig. The clamping apparatus comprises first and second jaw means for jaw gripping a drill string component, the first and second jaw means comprising first and second gripping means, respectively, for gripping respective corresponding engagement means of a respective end portion of the drill string component. The clamping apparatus further comprises jaw actuating means. The engagement means are arranged so as to allow clamping independently of the rotational position of the drill string component as seen with respect to its axis of symmetry. The invention also relates to a drill string component and a rock drilling rig.
Patent AU-2005231939-B2 (AU)
Title: Antiinflammatory lactones
Inventor: MEINGASSNER JOSEF GOTTFRIED
IPC: C07D309/36
Filed: 2005-03-31
Granted: 2008-05-22
Abstract: Lactones of Formula (I) which are pharmaceutically active in diseases associated with inflammation
Patent AU-2005247146-B2 (AU)
Title: Injection device
Inventor: BRADY MATTHEW
IPC: A61M5/20
Filed: 2005-05-27
Granted: 2010-05-27
Abstract: An injection device (110) is described having a housing (112) and a cap (130). The injection device (110) houses a syringe (114) having a needle (118) which is sealed by a boot (120). The cap (130) is arranged so that the boot (120) can be connected to the cap (130) simply, but cannot be removed from the cap (130). The housing (112) and cap (130) are arranged so that upon rotation of the cap (130), the cap (130) is moved axially away from the housing (112) and the boot (120) is removed from the syringe (114). The injection device is simple to use and manufacture.
Patent AU-2005283297-B2 (AU)
Title: Agent and food for preventing/improving functional digestive disorder
Inventor: TATSURO TANAKA
IPC: A23L27/23
Filed: 2005-09-16
Granted: 2011-12-08
Abstract: It is intended to provide an agent and a food for preventing/improving functional digestive disorder which contains, as the active ingredient, at least one member selected from among glutamic acid, 5’-nucleotides and salts thereof.
Patent AU-2006204396-B2 (AU)
Title: Method of mutagenesis
Inventor: THERESA GROVES MARIA ANASTASIA
IPC: C12Q1/68
Filed: 2006-01-09
Granted: 2011-08-11
Abstract: The present invention relates to a method of mutagenesis for introducing mutations into a molecule and, in particular, to methods that may be applied to populations of molecules for the generation or screening of libraries involving the mutation of multiple molecules.
Patent AU-2006248872-B2 (AU)
Title: Mobile dry feed dispenser for animals
Inventor: PASCAL LESCROART
IPC: A01K15/02
Filed: 2006-04-10
Granted: 2011-07-07
Abstract: The invention relates to a device which dispenses pellets when rolled by an animal. The inventive device consists of a central part (1) comprising two cylinders (2 and 3), one of which is nested inside the other, which are equipped with holes (4) of the same size. According to the invention, all or some of the holes in the two cylinders can be aligned more or less completely by manually rotating the external cylinder around the internal cylinder, such that a given number of pellets are released from the central part each time the device is rotated. The invention also comprises two wheels (7), one of which is equipped with a stopper (13).Said two wheels are fixed to the ends of the internal cylinder by means of screwing or gluing and with the aid of a double bayonet (8), and the cylinders are maintained in the selected relative position by a gear tooth system (11 and 12). The invention is particularly suitable for use as a toy, as a means of exercise and to slow down ingestion.
Patent AU-2006292228-B2 (AU)
Title: Protein kinase C peptide modulators of angiogenesis
Inventor: CHEN LEON E
IPC: C12N9/12
Filed: 2006-09-19
Granted: 2013-02-21
Abstract: The present invention provides peptides for inhibiting various protein kinase isozymes. The peptide can be directed to any region of the protein kinase C isozyme, and in one embodiment, is directed to the V5 domain. The peptide can be conjugated to a carrier, in a releasable or non-releasable manner. The peptides can be used to inhibit angiogenesis and/or vascular permeability. The peptides can be used to treat subjects having, for example, cancer, diabetic blindness, macular degeneration, rheumatoid arthritis, or psoriasis.
Patent AU-2006330706-B2 (AU)
Title: Advanced ultraviolet-resistant silver mirrors for use in solar reflectors
Inventor: GEE RANDY
IPC: F24S23/70
Filed: 2006-12-13
Granted: 2012-06-28
Abstract: A silver mirror construction that maintains a high percentage of hemispherical reflectance throughout the UV and visible spectrum when used in solar reflectors, comprising: a) a pressure sensitive adhesive layer positioned beneath a silver overlay; b) a polymer film disposed on the silver overlay; c) an adhesive layer positioned on the polymer film; and d) a UV screening acrylic film disposed on the adhesive layer.
Patent AU-2007201770-B2 (AU)
Title: Oven control
Inventor: WILLET PAUL EATON
IPC: G05B11/01
Filed: 2007-04-20
Granted: 2012-09-13
Abstract: A monitoring and advisory system for a plurality of ovens, including a means for receiving information from the plurality of ovens on the conditions in each oven and the usage of each oven, processor means for determining and identifying which of the 5 plurality of ovens meets a predetermined condition, based on the information received from the plurality of ovens, and forwarding an indication of the identified oven to an output means for interpretation by an operator. Heating means 12 14 16 18 Oven Chamber 1 Oven Chamber 2 Oven Chamber 3 Oven Chamber 4 20 22 24 26 Control system for Control system for Control system for Control system for chamber 1 chamber 2 chamber 3 chamber 4 Heating means 112 114 116 118 Oven Chamber 1 Oven Chamber 2 Oven Chamber 3 Oven Chamber 4 * ontrol System Communications Processor User interface/ means display
Patent AU-2007207830-B2 (AU)
Title: Eyewear frames with magnetic lens attachments
Inventor: DICHIARA CARMINE S
IPC: G02C1/00
Filed: 2007-01-11
Granted: 2012-03-01
Abstract: The present invention illustrates various methods of attaching a pair of eyeglass lenses or a lens shield to an eyeglass frame using magnets or magnetically attractive material. The magnetic attachment methods are beneficial because they allow the user to have interchangeable lenses or shields for indoor and outdoor use, enhancing their visual acuity during work or play. The lenses may be tinted, prescription, protective eyewear, or piano. The magnetic lenses are convenient and user friendly, allowing intuitive, tool-less interchangeability with no need to twist or stress the frame. These methods of attachment require no specific instructions or tools when the user replaces lenses.
Patent AU-2007216845-B2 (AU)
Title: System and method for return electrode monitoring
Inventor: BLAHA DEREK M
IPC: A61B18/14
Filed: 2007-09-19
Granted: 2013-05-16
Abstract: SYSTEM AND METHOD FOR RETURN ELECTRODE MONITORING A system for monitoring a plurality of return electrodes is disclosed. The system (1) includes a plurality of return electrodes (14, 15, 16) adhered to a patient and adapted to couple to an electrosurgical generator (10) configured to generate an electrosurgical current. The system (1) also includes a current monitor (43, 53, 63) connected in series with each of the plurality of the return electrodes (14, 15, 16) to measure a current signal passing therethrough and a processor (26) coupled to each of the current monitors (43, 53, 63). The processor (26) is configured to determined a desired current ratio and an actual current ratio for each of the plurality of the return electrodes (14, 15, 16) as a function of the current passing through each of the plurality of the return electrodes (14, 15, 16). The processor (26) is further configured to compare the desired current ratio and the actual current ratio. t15 12 GENERATOR FiG. 1
Patent AU-2007258955-B2 (AU)
Title: Industrial process for the synthesis of 17alpha-acetoxy-11beta-[4-(N,N-dimethyl-amino)- phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process
Inventor: VISKY GYORGY
IPC: C07J71/00
Filed: 2007-05-18
Granted: 2012-09-20
Abstract: The present invention relates to a new industrial process for the synthesis of solvate- free 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB -2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process. The process according to the invention is the following: i) 3-(ethylene-dioxy)-estra-5(10),9(11)-diene-17-one of formula (X) is reacted with potassium acetilyde formed in dry tetrahydrofuran by known method, ii) the obtained 3-(ethylene-dioxy)-17α-ethynyl-17β-hydroxy-estra-5(10),9(11)-diene of formula (IX) is reacted with phenylsulfenyl chloride in dichloromethane in the presence of triethylamine and acetic acid, iii) the obtained isomeric mixture of 3-(ethylene-dioxy)-21-(phenyl-sulfinyl)-19-norpregna-5(10),9(11),17(20),20-tetraene of formula (VIII) is reacted first with sodium methoxide in methanol, then with trimethyl phosphite, iv) the obtained 3-(ethylene-dioxy)-17α-hydroxy-20-methoxy-19-norpregna-5(10),9(11),20-triene of formula (VII) is reacted with hydrogen chloride in methanol, then v) the obtained 3-(ethylene-dioxy)-17α-hydroxy-19-norpregna-5(10),9(11l)-diene-20- one of formula (VI) is reacted with ethylene glycol hi dichloromethane in the presence of trimethyl orthoformate and p-toluenesulfonic acid by known method, vi) the obtained 3,3,20,20-bis(ethylene-dioxy)-17α-hydroxy-19-norpregna- 5(10),9(11)-diene of formula (V) is reacted with hydrogen peroxide in a mixture of pyridine and dichloromethane in the presence of hexachloroacetone by known method, vii) the obtained 3,3,20,20-bis(ethylene-dioxy)-17α-hydroxy-5,10-epoxy-19-norpregn-9(11)-ene of formula (IV), containing approximately a 1:1 mixture of 5α,10α- and 5β,10β-epoxides, is isolated from the solution and reacted with a Grignard reagent obtained from 4-bromo-N,N-dimethyl-aniline in tetrahydrofuran in the presence of copper(I) chloride catalyst without separation of the isomers by known method, viii) the obtained 3,3,20,20-bis(ethylene-dioxy)-5α,17α-dihydroxy-11β-[4-(N,N-dimethylamino)-phenyl]-19-norpregn-9(11)-ene of formula (III) is reacted with potassium hydrogensulfate in water by known method, ix) the obtained 11β-[4-(N,N-dimethylamino)-phenyl]-17α-hydroxy-19-norpregn-4,9-diene-3,20-dione of formula (II) is acetylated with acetic anhydride in the presence of perchloric acid by known method, finally x) the solvate-free compound of formula (I) is liberated from the obtained solvate containing compound of formula (I) in a 1 : 1 mixture of ethanol and water at 70° C.
Patent AU-2007278195-B2 (AU)
Title: Macrolide synthesis process
Inventor: BRINK MONIKA
IPC: C07H17/08
Filed: 2007-07-26
Granted: 2012-09-13
Abstract: This invention relates to a method for making macrolides, and, in particular, to a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl- tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, , may be used to make macrolides.
Patent AU-2007321323-B2 (AU)
Title: Method for handling large amounts of standard airline fares data
Inventor: CEDRIC DOURTHE
IPC: G06F17/30
Filed: 2007-11-09
Granted: 2011-09-29
Abstract: A method for handling large amounts of standard data contained in one or more databases conforming to a standard data model is described. When large amounts of standard data are needed to answer requests of end-users of a software application the method of the invention assumes that a significantly reduced amount of metadata useable by the software application are first built out of the large amounts of standard data. The metadata are stored in an intermediate database of metadata and delivered to the software application through a metadata engine in lieu of the large amounts of standard data. The invention allows software application to consider much larger amounts of standard data to better answer end-user requests in an acceptable elapsed time.
Patent AU-2008200246-B2 (AU)
Title: Aggregate for concrete and construction
Inventor: KAYALI OBADA
IPC: C04B18/02
Filed: 2008-01-18
Granted: 2010-06-24
Abstract: The present invention relates generally to a method of forming a lightweight fly ash aggregate together with the resultant fly ash aggregate. The invention further relates to various aspects of the method of forming the lightweight fly ash aggregate including methods of forming fly ash slurry, briquettes, or lightweight fly ash particles. The general steps involved in forming a lightweight fly ash aggregate are as follows:I. blending fly ash together with a plasticiser and a reduced quantity of water;II. compacting or compressing the resultant fly ash slurry or dough;III. cutting or otherwise forming the dough into briquettes;IV. heating the briquettes to effectively cure the dough;V. firing the briquettes to sinter the fly ash;VI. crushing the sintered briquettes and sizing, preferably screening, the resultant fly ash particles to provide the lightweight fly ash aggregate of a predetermined size range.
Patent AU-2008200630-B2 (AU)
Title: A power supply system
Inventor: DESMOND ROWE ANDREW
IPC: F21V21/34
Filed: 2008-02-08
Granted: 2011-08-25
Abstract: A power supply system for use in an exhibition stand arrangement that can be re used while also being easy to install and uninstall. The power supply system having an elongate member forming a transverse member of the frame of a stand arrangement comprising a power inlet connectable to a power supply and a power outlet, and a circuit connecting the power inlet and power outlet. The system further including a power take off unit with a power inlet and at 0 least two power outlets and a plurality of connecting means wherein the power supplied from the system can be provided a another power supply system by using an electrical connection means connected between the power outlet of the power supply system and the power inlet of the power take off unit and a further electrical connection means connected between the power outlet of the power take off unit and 5 the other power supply system of a desired portion of the exhibition stand. -1/4 knr
Patent AU-2008203464-B2 (AU)
Title: Sequential drug delivery systems
Inventor: SIEBERT JOHN M
IPC: A61K31/5415
Filed: 2008-08-01
Granted: 2010-07-01
Abstract: The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired site in a body of the mammal, and, sequentially, at the desired site, promoting dissolution and absorption of the active ingredient. In a preferred embodiment, the ph of the localized environment of the active ingredient is sequentially modified to promote dissolution and absorption.
Patent AU-2008221550-B2 (AU)
Title: Solanum bulbocastanum polyubiquitin Bul409 promoter and uses thereof
Inventor: BELKNAP WILLIAM R
IPC: A01H4/00
Filed: 2008-09-19
Granted: 2015-01-22
Abstract: SOLANUM BULBOCASTANUM POLYUBIQUITIN PROMOTER AND USES The present invention relates to isolated Solanum Bulbocastanum Bul409 promoter sequences and uses thereof czJ cq. (I) C: C)j C\j M) co - (0 LO) t~j M~ N~ 0
Patent AU-2008237166-B2 (AU)
Title: Apparatus and method for sculpting the surface of a joint
Inventor: KOHLER ROBERT E
IPC: A61B17/56
Filed: 2008-04-04
Granted: 2014-06-12
Abstract: Methods and devices for sculpting bones, particularly in preparation for implanting prosthetic devices to replace articulating bone joint surfaces. Improved bone removal devices including burr mills driven by gears and loop drives are provided. Reciprocating cutters and belt cutters are also provided. Some devices have either integral or removable expandable portions to vary the force and bone resection depth. Devices can have irrigation ports and plenums to remove bone fragments. Some cutters are dual cutters, adapted to remove bone in two or more regions, such as the knee joint, simultaneously.
Patent AU-2008253825-B2 (AU)
Title: Gas valve and production tubing with a gas valve
Inventor: JOHANNESEN EILIF H
IPC: F16K17/34
Filed: 2008-05-22
Granted: 2011-10-27
Abstract: A valve (30) for a production liner (12) in connection with the extraction of oil and gas, arranged to automatically shut of the flow of fluid into the production liner (12) in the event of a gas break-through, whereby the valve (30) comprises a valve seating (32) containing at least one central inflow channel (34) and one or more outflow channels (36, 38) from the valve (30). The valve (30) is constructed with a curved design equal to the shape of the outer diameter of the production liner (12), and is placed on the outside of the production liner (12), and in that a rectangular shut off disk (40) with the same curving is arranged in the valve (30), in the flowing path of the liquid flow, to cause a high velocity flow over the shut off disk's surface (40a) against the valve seat (32), wherein the shut off disk (40) is adapted to seal against said valve seat (32) dependant on the differential pressure being produced by the viscosity of the passing flow. The invention also comprises a production liner containing a valve.
Patent AU-2008262164-B2 (AU)
Title: System and method for using vehicle attributes to identify a vehicle under service
Inventor: KRZYSTOFCZYK CARL J
IPC: G06F7/00
Filed: 2008-05-02
Granted: 2011-09-08
Abstract: A system and method directed to determining vehicle attributes associated with a vehicle under service so as to eliminate the need for a user of a vehicle service tool to enter the vehicle attributes or to reduce the quantity of vehicle attributes that the user has to enter in order for the vehicle service tool to identify the vehicle under service and, in turn, to retrieve vehicle reference data associated with the vehicle under service. The vehicle service tool may include vehicle service applications for servicing various systems and/or components of the vehicle under service. A vehicle service application selected by the user may function as a requestor application that queries other applications and/or data storage for the vehicle attributes needed by the requestor application to identify the vehicle under service.
Patent AU-2008293425-B2 (AU)
Title: Solid-state protein formulation
Inventor: GADGIL HIMANSHU
IPC: A61M5/24
Filed: 2008-08-29
Granted: 2014-09-18
Abstract: Provided are systems comprising delivery vehicles for the stable storage of immobilized proteins, e.g., protein therapeutics, in a form amenable to administration, such as by injection or infusion, in combination with an elution fluid. Also provided are proteins adsorbed to chromatography media in a form compatible with a one-step administration of the protein. Exemplary delivery vehicles are pre-filled syringes and pre-filled infusion modules; exemplary proteins are antibodies useful in therapy. Also provided are methods of producing the immobilized proteins and methods of using the immobilized proteins, e.g., protein therapeutics.