baber/WOPTO huggingface dataset:
Patent WO-2023196888-A1 (WO)
Title: Méthodes de traitement du carcinome à cellules squameuses de la tête et du cou
Inventor: BURROWS FRANCIS
IPC: A61K31/4439
Filed: 2023-04-06
Abstract: La présente invention concerne des méthodes de tipifarnib en combinaison avec un inhibiteur de PI3K, tel que l'alpélisib, pour le traitement, la prévention ou la gestion du carcinome à cellules squameuses de la tête et du cou (HNSCC).
Patent WO-2023212563-A1 (WO)
Inventor: ZHAO LIPING
IPC: G16B20/00
Filed: 2023-04-25
Abstract: L'invention concerne des méthodes et des systèmes pour déterminer un état de maladie par l'obtention d'une première pluralité de séquences d'acide nucléique pour l'ADN génomique à partir d'un échantillon provenant de l'intestin d'un sujet. Les méthodes et les systèmes consistent à déterminer, à partir des séquences d'acides nucléiques, une première pluralité de valeurs d'abondance génomique pour une première pluralité de bactéries intestinales et une deuxième pluralité de valeurs d'abondance génomique pour une deuxième pluralité d'au moins 20 espèces de bactéries intestinales. Les méthodes et les systèmes consistent également à appliquer un modèle à au moins la première pluralité de valeurs d'abondance génomique et à la deuxième pluralité de valeurs d'abondance génomique, ou une ou plusieurs combinaisons de celles-ci, ce qui permet de déterminer l'état de maladie du sujet en tant que sortie du modèle.
Patent WO-2018187821-A1 (WO)
Title: Moteur actionné par la force d'archimède
Inventor: VU Huy Toan
IPC: F03B17/04
Filed: 2017-09-15
Abstract: La présente invention concerne un moteur actionné par la force d'archimède. Ce moteur comprend:-une pluralité de flotteurs (3) reliés en communication l'un à l'autre pour former une chaîne flottante complètement fermée, le volume total d'air à l'intérieur de la chaîne étant constant; des espaces définis entre des premiers rails de redirection de flotteur (5.1) et des sections correspondantes de courroies ou de chaînes (4), lesdits espaces ayant tendance à s'agrandir progressivement de telle sorte que chaque fois que les flotteurs en état dégonflé sous les premières roues entraînées (9.1) émergent, lesdits flotteurs seront gonflés par de l'air provenant des flotteurs situés au-dessus, la pression régnant dans la chaîne flottante étant maintenue constante ; des espaces définis entre des premiers rails de redirection de flotteur (5.2) et des sections correspondantes des courroies ou chaînes (4), lesdits espaces ont tendance à se rétrécir progressivement de manière à dégonfler progressivement les flotteurs et à expulser l'air contenus dans les flotteurs vers les flotteurs suivants qui émergent vers le haut ; et des roues motrices (15) avec des bras (14) qui sont poussés par des broches de transmission de force (2.1) fixés à chaque flotteur lorsque les flotteurs (3) sont immergés vers le bas dans le cas des roues motrices (15) fixées coaxialement aux roues entraînées (9.1), ou lorsque les flotteurs (3) émergent vers le haut dans le cas des roues motrices (15) fixées indépendamment aux roues entraînées (9.1), un arbre principal (6) du moteur étant entraîné en rotation.
Patent DK-201500833-A1 (DK)
Title: Minkopdrætsanlæg
Inventor: MADSEN JENS JØRGEN
IPC: A01K7/06
Filed: 2015-12-22
Abstract: Et minkopdrætsanlæg (1) omfatter en række (2b) af med mellemrum (5) anbragte minkbure (3), som hver har en bundvæg (21), gittersidevægge (22,23) og en frontvæg (11), hvortil der er knyttet en redekasses (4) redekassebagvæg (13) med en redekasseåbning (12) Anlægget omfatter yderligere en langs rækken af bure forløbende drikkevandsledning (10) hørende til et drikkevandssystem. I burene er der på en sidevæg (22) anbragt en drikkeventil (16), som har et nedadvendende udløb og i tilknytning hertil en nedadvendende udragende aktiveringsstift, og som er forbundet med drikkevandsledningen (10). Ventilen er konfigureret til ved en let berøring eller påvirkning af aktiveringsstiften at afgive vand, i det mindste i form af en dråbe. Aktiveringsstiften er beliggende 3-5 cm over burrets bundvæg og højst 15 cm fra den nærmestliggende kant af redekasseåbningen.
Patent DK-201771036-A1 (DK)
Title: Hängbeslag för uppbärande av en skivenhet
Inventor: BERNT FELLMAN
IPC: E06B3/54
Filed: 2017-12-29
Abstract: Uppfinningen avser ett hängbeslag (1) för uppbärande av en skivenhet företrädesvis i form av en glasskiva (6) för att kunna hängas utan håltagning och synliga skruvinfästningar från sidan, vilket hängbeslag (1) innefattar minst ett bärelement (2) från vilket sträcker sig två, i huvudsak parallella, på ett förutbestämt avstånd från varandra belägna skänklar (3,4) för bildande av en U-formation (5) för greppande kring ett övre kantparti (7) av den i hängbeslaget (1) monterade skivenheten (6), vilka skänklars avstånd från varandra är reglerbart medelst fästbultar (10) relativt varandra och somsträcker sig genom hål (8) i skänklarnas bottenparti från ett bärelement (2) och ner genom U-formationen och minst en i denna placerad packning (11), vilken packning fungerar såsom en mutter med invändig gänga (12) för samverkan med en gängformation (3) i fästbultarnas (10) fria ändar (13) i och för åstadkommande av en klämverkan mellan skänklarna (3,4) vid iskruvning av fästbultarna (10) i packningen
Patent DK-202000243-A1 (DK)
Title: High Pressure On-Stream Injector
Inventor: Nils Fog Gjersøe
IPC: E21B33/068
Filed: 2020-02-25
Abstract: Injection system for deployment of fluid injection into a flowline such as typically used in onshore or offshore process plant applications, the system being characterized by fitting the system and carrying out injection as well as removing the system again is possible into high pressure flowlines without production stop, this being achieved by a movable injection wing with nozzles which can be inserted and retracted without breaking the main high pressure isolations of the flowline system, the movable parts having no mechanical penetrations only driven for insertion and retraction by the injection pressure, respectively the flowline pressure.
Patent PH-12014501454-A1 (PH)
Title: Methods of treating hematologic cancers using pnp inhibitors such as forodesine in combination with alkylating agents or anti-cd20 agents
Inventor: SHANTA BANTIA
IPC: A61K31/4184
Filed: 2014-06-24
Abstract: The present application relates to treatment of hematologic cancers, which treatments can include, e.g., administration of a purine nucleoside phosphorylase (PNP) inhibitor, an alkylating agent and/or an anti-CD20 agent, and related compositions and kits.
Patent PH-12014501483-A1 (PH)
Title: Sulfide scavengers, methods for making and methods for using them
Inventor: GREGORY KAPLAN
IPC: C10G29/20
Filed: 2014-06-26
Abstract: Methods for making sulfide scavenging compositions are provided. The method comprises reacting at least one secondary amine with at least one aldehyde and solvent in the presence of a catalyst to form a reaction composition, wherein a reaction temperature is less than or equal to 90 �C. Sulfide scavengers using the above method are also disclosed. Methods for removing sulfides from fluid streams are also provided. The methods include adding the above sulfide scavengers to fluid streams.
Patent PH-12014502305-A1 (PH)
Title: Intracorneal lens
Inventor: WERNER BERNER
IPC: A61F2/16
Filed: 2014-10-14
Abstract: The present invention relates to an intracorneal lens (1), comprising a circular main body having a convex front surface and a convex rear surface, characterized in that the convex front surface has a single uniform radius of curvature (Rcv) and the concave rear surface has a radius of curvature (Rcci). The radius of curvature (Rcci) of the concave rear surface is greater than the average radius of the cornea by 0.1 mm to 2 mm, preferably 0.2 to 1.5 mm, in particular preferably 0.5 to 1 mm. The present invention further relates to a kit, comprising a storage unit (15) and a pre-load unit (P) inside the storage unit (15). The storage unit (15) is made of a watertight material and can be closed watertight by means of a plug (16). The pre-load unit (P) is fitted with the intracorneal lens according to the invention.
Patent PH-12014502338-A1 (PH)
Title: Smoking article mouthpiece with cooling agent inclusion complex
Inventor: ALEN KADIRIC
IPC: A24D3/18
Filed: 2014-10-20
Abstract: A smoking article includes a mouthpiece having an outer surface and a cooling agent inclusion complex disposed on the outer surface.
Patent PH-12015501517-A1 (PH)
Title: Pyrimidone derivatives and their use in the treatment, amelioration or prevention of a viral disease
Inventor: WOLKERSTORFER ANDREA
IPC: A61K31/519
Filed: 2015-07-03
Abstract: The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,codrug, cocrystal,prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
Patent PH-12015502469-A1 (PH)
Title: Fcrn-binding abolished anti-igf-ir antibodies and their use in the treatment of vascular eye diseases
Inventor: GUIDO HARTMANN
IPC: C07K16/28
Filed: 2015-10-26
Abstract: The invention provides anti-IGF-1R antibodies with abolished FcRn-binding and methods of using the same for the treatment of vascular eye diseases.
Patent PH-12016500070-A1 (PH)
Title: Humidity activated formulation for volatile compounds
Inventor: ALEXANDER WILLIAMSON
IPC: A01N25/10
Filed: 2016-01-11
Abstract: This invention is related to controlled release formulations of volatile antimicrobial compounds against pathogens affecting meats, plants, or plant parts or dairy products. Provided are delivery systems in the form of coatings or films, where controlled release of their volatile components in vapor form is triggered by high relative humidity. The volatile component may include, for example volatile antimicrobial liquids including low molecular weight alcohols and/or aldehydes, 1 -methylcyclopropene, and/or other volatile fungicides.
Patent PH-12016501520-A1 (PH)
Title: Beverage powder
Inventor: SULEMANJI NAWAZ
IPC: A23F5/36
Filed: 2016-08-01
Abstract: The present invention relates to a method for preparing a foaming beverage powder, the method comprising: providing a porous beverage powder; heating the porous beverage powder to a temperature below its glass transition temperature in a gas-containing atmosphere; increasing the pressure of the gas-containing atmosphere to thereby raise the temperature of the porous beverage powder to a temperature above its glass transition temperature; and then decreasing the pressure of the gas-containing atmosphere to thereby lower the temperature of the porous beverage powder to a temperature below its glass transition temperature.
Patent PH-12016502051-A1 (PH)
Title: Reception device, reception method, transmission device, and transmission method
Inventor: NAOHISA KITAZATO
IPC: H04N21/433
Filed: 2016-10-14
Abstract: Provided are a reception device and a reception method for receiving a file in MMT format. Transmitted from the transmission side are resources constituting an application, information whereby a URL indicating a location in the application is mapped to a location on an MMT transmission channel for broadcast, etc., and information showing the link relationship to a display unit of the application. The range of access to hierarchical file data when a data broadcast application is to be executed, and the location information and size of the file data in the access range are retrieved on the receiver side, and effective advance caching is performed for the application.
Patent PH-12016502071-A1 (PH)
Title: Set of eyeglass-lens semifinished products and method for the design of said set, method and device for producing eyeglass lenses, and use of a set of semifinished products
Inventor: GEORG MICHELS
IPC: G02C7/02
Filed: 2016-10-18
Abstract: The invention relates, among other things, to the provision of a set (68) of eyeglass-lens semifinished products composed of at least three series (66-1, 66-2, 66-3) of eyeglass-lens semifinished products having spherical or rotationally symmetric aspherical front surfaces. The series (66-1, 66-2, 66-3) of eyeglass-lens semifinished products differ in pairs in the base material of said series. The base materials have different average indices of refraction. Each of the series (66-1, 66-2, 66-3) comprises, within an actual surface refractive-power range of the front surface thereof in relation to a standard index of refraction of 1.53 between 3.2 D and 6.7 D, at least three types (No. 7, No. 10, No. 13) of eyeglass-lens semifinished products, which types differ in pairs and the front-surface shapes of which types are designed differently in some way. Within said actual surface refractive-power range of the front surface of the series in relation to a standard index of refraction of 1.53 between 3.2 D and 6.7 D, the front-surface shapes of said at least three types (No. 7, No. 10, No. 13) are identical on a central partial surface (which preferably comprises more than 40 pcnt , more preferably more than 50 pcnt of the total front surface) or the entire front surface of the type for all of the at least three series (66-1, 66-2, 66-3).
Patent PH-12017501007-A1 (PH)
Title: Compositions comprising 2-((1-(2 - (4-fluorophenyl) -2- oxoethyl) piperidin-4-yl) methyl) isoindolin-1-one for treating schizophrenia
Inventor: LUTHRINGER REMY
IPC: C07D401/06
Filed: 2017-05-31
Abstract: The disclosure provides a novel polymorph of Compound (I):, 2-((l-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4- yl)methyl)isoindolin-l-one monohydrochloride dihydrate, i.e., Form (A) of Compound (?)-??-2?2O. Pharmaceutical compositions comprising Form (A) of Compound (?)-??-2?2O and related methods of treatment are also disclosed.
Patent PH-12017502312-A1 (PH)
Title: Washing machine
Inventor: YUHARA SATORU
IPC: D06F39/08
Filed: 2017-12-14
Abstract: A washing machine according to the present disclosure is provided with: a storage tub for storing laundry; a bubble generation unit, provided in the storage tub, for supplying generated bubbles into the storage tub; a water supply channel, provided in the storage tub, for supplying a washing liquid to the bubble generation unit; a circulating water channel, provided in the storage tub, for circulating the washing liquid inside the storage tub in the storage tub; and a circulation pump for supplying the washing liquid inside the storage tub to the bubble generation unit and the circulating water channel. The water supply channel and the circulating water channel are disposed one on top of another in the axial direction of the storage tub. Thus, it is possible to realize a washing machine having high detergency without impairing the aperture area of a laundry input opening.
Patent PH-12017550117-A1 (PH)
Title: Digital assistant extensibility to third party applications
Inventor: SURTI TANVI
IPC: H04L29/08
Filed: 2017-10-17
Abstract: A digital assistant includes an extensibility client that interfaces with application extensions that are built by third-party developers so that various aspects of application user experiences, content, or features may be integrated into the digital assistant and rendered as native digital assistant experiences. Application extensions can use a variety of services provided from cloud-based and/or local sources such as language/vocabulary, user preferences, and context services that add intelligence and contextual relevance while enabling the extensions to plug in and operate seamlessly within the digital assistant context. Application extensions may also access and utilize general digital assistant functions, data structures, and libraries exposed by the services and implement application domain-specific context and behaviors using the programming features captured in the extension. Such extensibility to third party applications can broaden the scope of the database of information that the digital assistant may use to answer questions and perform actions for the user.
Patent PH-12018502716-A1 (PH)
Title: Nicotine particles delivery consumable
Inventor: ZUBER GERARD
IPC: A24F42/60
Filed: 2018-12-21
Abstract: A nicotine particle delivery consumable article includes a receptacle having a body extending from a receptacle first end to an opposing receptacle second end and defining a cavity. A capsule is disposed within the cavity. The capsule contains particles including nicotine. The receptacle includes a membrane sealing the receptacle first end and an air outlet extending through the receptacle second end and into the cavity. An air inlet, close to the receptacle first end, extends through a side wall of the body and into the cavity.
Patent PH-12019000453-A1 (PH)
Title: A gaming machine providing an insurance payout and a playing method thereof
Inventor: INAMURA YUKINORI
IPC: A63F9/24
Filed: 2019-11-25
Abstract: A slot machine 10 as a gaming machine executes a unit game, after accepting a bet, counts the number of times a unit game is executed, and, in a case where the number of times counted is a predetermined number, determines an insurance payout amount on the basis of an average amount of the bet specified in the games counted.
Patent PH-12019050282-A1 (PH)
Title: (OHMy) Board Game
Inventor: YANTO ANTHONY B
IPC: A63F3/02
Filed: 2019-12-04
Abstract: Many board games challenge and develop students' critical and logical thinking skills. Applying these as educational materials is an effective way to employ cooperative learning in the classroom and to master the lesson. One of the problems in teaching electrical subjects is the familiarization of the basic electrical principles. In this view, OHMy board game involves the students to solve and familiarize basic electrical principles specifically the Ohm's Law which is to be played by at least two players comprising of a rectangular game board, a two sets of playing pieces and a process of playing the game. Students will be entertained while learning, hence, this invention is crafted.
Patent PH-12019500152-A1 (PH)
Title: Anti-gprc5d antibodies, bispecific antigen binding molecules that bind gprc5d and cd3, and uses thereof
Inventor: ATTAR RICARDO
IPC: C07K16/28
Filed: 2019-01-21
Abstract: Provided herein are antibodies that specifically bind to GPRC5D. Also described are related polynucleotides capable of encoding the provided GPRC5D-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor GPRC5D-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with GPRC5D-expressing cancer and thus may be amenable to treatment with a GPRC5D-specific anti-cancer therapeutic, such as the multispecific antibodies against GPRC5D and CD3 described herein.
Patent PH-12019500794-A1 (PH)
Title: Method and system for storing and accessing bioinformatics data
Inventor: RENZI DANIELE
Filed: 2019-04-11
Abstract: Method and system for storing and accessing genomic data. Genomic sequencing data are partitioned into access units of different types based on the predictability of the contained data. Access units are classified in different types and the structuring enables selective access and selective processing of genomic data.
Patent PH-12019501927-A1 (PH)
Title: Combustion apparatus
Inventor: MINE TOSHIHIKO
IPC: F23L9/02
Filed: 2019-08-20
Abstract: The purpose of the invention is to inhibit ash and the like floating in a furnace from adhering above and below an opening that discharges after-air into a furnace. A boiler (10A) comprises a furnace (11), a burner that burns a fuel with less than the theoretically required amount of air, and an after-air supply unit that supplies after-air to the furnace (11) for burning the fuel in an unburned state after burning in the burner. The after-air supply unit comprises: a first nozzle (32) that discharges the after-air so as to go straight toward the interior of the furnace (11); a second nozzle that deflects the after-air discharged toward the interior of the furnace (11) in a direction away from the first nozzle (32) to both the left and right sides in the horizontal direction; an expanding diameter face (16) that gradually increases in diameter toward the interior of the furnace (11) and that is continuous with a front wall (15f) or a rear wall (15r) of a furnace wall (15); and a guidance member (40A) by which a portion of the after-air discharged from the interior of a casing (31) to the inside of the furnace (11) flows along the expanding diameter face (16).
Patent PH-12020050173-A1 (PH)
Title: A footing
Inventor: MICHAEL MICHAEL
IPC: E02D27/50
Filed: 2020-06-12
Abstract: A footing member 1 comprising a body portion 3 (defining a substantially-vertical-wall-arrangement 3b surrounding a plate), threaded fastening portions 5 and three or more pile guides 7 (through which piles are driveable). An integral body 3 defines the body portion and the threaded fastening portions.
Patent PH-12020551811-A1 (PH)
Title: Freeze-dried cosmetic composition
Inventor: LIU XING
IPC: A61Q19/00
Filed: 2020-10-28
Abstract: Disclosed is a freeze-dried cosmetic composition comprising 10 to 70 pcnt of water-soluble active by weight of the freeze-dried cosmetic composition, polyhydric alcohol, and galactomannan.
Patent PH-12020551998-A1 (PH)
Title: Stabilized emulsions with acidic agents
Inventor: HUTSON ASHLEY L
IPC: A61Q1/06
Filed: 2020-11-20
Abstract: The combination of polyols with certain active ingredients has been found to mitigate the potential irritating nature of some active ingredients (e.g., hydroxy acids, etc.). When applied to lips, this combination may provide for therapeutic and/or cosmetic benefits including smoother lips, increased moisturization, reduced water loss and combinations thereof. However, formulating stable emulsions with certain active ingredients has proved problematic. The present application also provides new stabilization mechanisms for the emulsions involving alteration of the extensional viscosity of the internal phase.
Patent PH-12021550315-A1 (PH)
Title: Photoprotective compositions containing malassezia-derived compounds and/or chemical analogs thereof
Inventor: EINZIGER MICHAEL
IPC: C07D487/04
Filed: 2021-02-11
Abstract: The present invention relates to compounds, compositions, and methods for modulating skin pigmentation and treating or preventing UV-induced skin damage, erythema, aging of the skin, sunburn, and hyperpigmentation in a subject. The compounds, compositions, and methods of the present invention generally involve Malassezia- derived compounds, including malassezin and indirubin, and/or chemical analogs thereof. Other applications of the compounds and compositions disclosed herein include, but are not limited to, improving hyperpigmentation caused by a hyperpigmentation disorder, inducing melanocyte apoptosis, and modulating atylhydrocarbon receptor (AhR) activity, melanogenesis, melanin production, melanosome biogenesis, melanosome transfer, melanocyte activity, and melanin concentration.