baber/WOPTO huggingface dataset:
Patent ES-492488-A0 (ES)
IPC: A61P3/00
Filed: 1980-06-16
Abstract: The compounds of formula (II); 
<CHEM>
 in which R1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group, R4 is an alkyl group of 1 to 10 carbon atoms substituted by a hydroxyl, lower alkoxyl, oxo, lower acyloxy or OCH2CO2H group or lower alkyl ester thereof; R5 is a hydrogen, chlorine or fluorine atom of a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, ethyl or propyl group; R7 is a hydrogen atom or a methyl, ethyl or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond, have been found to possess anti-obesity and/or anti-hyperglycaemic activity. They are prepared by for analogous compounds usual methods.
Patent ES-508170-A0 (ES)
IPC: C01B11/06
Filed: 1981-12-21
Abstract: Process and plant for the preparation of concentrated aqueous solutions of alkali metal hypochlorite, in which a suspension of crystals of alkali metal chloride in an aqueous solution of alkali metal hypochlorite is circulated from bottom to top in a tubular reaction chamber located in an enclosure, chlorine and an aqueous solution of alkali metal hydroxide are reacted in this suspension in the chamber, a fraction of the resulting suspension leaving the open upper part of the chamber, overflows out of the enclosure and is filtered to separate the crystals, and the remaining fraction of the suspension is kept in the enclosure where it is recycled to the base of the reaction chamber.
Patent ES-509773-A0 (ES)
IPC: F02B33/34
Filed: 1982-02-19
Abstract: 1. A method of reducing fuel consumption in an internal combustion engine of given cylinder capacity, in particular for a motor vehicle, using a Rankine cycle circuit to recover at least part of the heat energy dissipated by the engine, to transform the recovered energy into mechanical energy, and then to deliver the mechanical energy to the engine and/or to its accessories, and in supercharging the engine (M) with air by means of a compressor, characterized in that the Rankine cycle circuit and the engine supercharging compressor (S) are independent from each other, the compressor (S) being driven mechanically by the engine (M) only whenever it is necessary to obtain maximum performance or power corresponding to those of an engine of greater cylinder capacity ; the Rankine cycle having maximum efficiency at low engine output powers lying between about 0% and about 50% of the maximum power from said engine.
Patent ES-518702-A0 (ES)
IPC: B01D39/18
Filed: 1982-12-30
Abstract: A multilayer filter material is described which comprises a coarse and a fine filter layer, while the individual filter layers contain a share of natural fibres and are interconnected with each other on the paper machine, without the use of a bonding agent, whereby the coarse filter layer consists of a mixture of natural and synthetic fibres and at least one part of said synthetic fibres is structured, and synthetic fibres lying on the surface of the coarse filter layer protrude from the plane of the filter material. Moreover a process for the manufacture of the multilayer filter material and its use is described. The inventive multilayer filter material is distinguished against comparable conventional filters by an increased service life and a better degree of separation.
Patent ES-540858-A0 (ES)
IPC: C07D487/10
Filed: 1985-03-01
Abstract: A series of novel spiro-oxindole imidazolidinedione derivatives have been prepared, including their pharmaceutically acceptable salts. These compounds are useful in therapy as aldose reductose inhibitors for the control of certain chronic diabetic complications. Preferred compounds include 6'-amino-spiro- [imidazolidine-4,3'-indoline] -2,2', 5-trione, 5'-chloro -7'-amino-spiro [imidazolidine-4,3'-indofine) -2,2', 5-trione, 1'- (3-pyridylmethyl) -5'-fluoro-spiro [imidazolidine-4,3'-indoline) -2,2',5-trione, 1'- (3-pyridylmethyl) -5',7'-dichloro-spiro- [imidazolidine-4,3'( indoline] -2,2',5-trione and spiro- [imidazolidine-4,3'- (6- azaindoline)1 -2,2',5-trione. Methods for preparing these compounds from known starting materials are provided.
Patent ES-544888-A0 (ES)
IPC: G01N21/07
Filed: 1985-07-05
Abstract: In a process for carrying out an analytical determination by mixing and incubating a sample liquid with at least one dry reagent which is soluble therein to form a reaction mixture liquid and measuring a parameter in the reaction mixture liquid, the sample liquid is first transported along a transport path to the soluble dry reagent and the resulting reaction mixture liquid then further transported along the transport path. The further transporting of the reaction mixture liquid along the transport path is under the influence of a force-change cycle in which centrifugal force and a further force alternately predominate to determine the direction of the further transporting along the transport path. At least one further liquid is transported on another path, part of which is separate from and part of which is common with the transport path, by the force-change cycle in such a manner that at least two of the liquids pass through the common part of the transport path chronologically separated.
Patent ES-551821-A0 (ES)
IPC: C07K7/02
Filed: 1986-02-11
Abstract: The invention relates to peptide derivatives modeled on the basis of pepstatin. These derivatives inhibit renin and acid proteases.
Patent FI-841524-A0 (FI)
Inventor: BARR PHILIP J
IPC: C12N15/81
Filed: 1984-04-16
Abstract: Prodn. of human insulin-like growth factor (IGF) comprises growing host cells contg. a structural gene which comprises a functional DNA construct of the gene encoding IGF joined in proper reading frame with secretory leader and processing signal sequences recognised by the host, and isolating secreted human IGF. The structural gene is downstream from and under transcriptional regulatory control of a transcriptional initiation region in a vector compatible with the host. The host is pref. a yeast. A DNA construct comprising a coding sequence for human IGF under transcriptional regulation of regulatory signals utilised by yeast is new. Also claimed is a construct contg. the IGF gene for expression in a cultured cellular host. Nucleotide sequences are defined with corresp. aminoacid sequence.
Patent FI-861235-A0 (FI)
Inventor: KING MICHAEL JOHN
IPC: B29D30/54
Filed: 1986-03-24
Abstract: A device for use in vulcanizing a premolded, precured tyre tread (13) to a tyre carcass (12) in a tyre retreading operation, for sealing a retreading envelope against the tyre carcass in the bead area of the tyre. The device comprises a pair of rigid circular ring members each sized to fit against the exterior bead portion of the tyre casing, with the envelope interposed between the ring and the tyre casing. A series of interconnecting springs are attached to the rings at circumferentially spaced apart locations to hold them against the tyre in the bead area, and spacers attached to at least some of said springs maintain a uniform distance between the bead portions of the tyre casing. A compression member on an edge of each ring member provides increased sealing pressure against the envelope on the tyre.
Patent FI-872034-A0 (FI)
Inventor: HOWELL BARRY GEORGE
IPC: C08K3/22
Filed: 1987-05-07
Abstract: A flame-retardant cross-linkable polymer composition for extrusion which is capable of producing non-porous products comprises: at least one flame-retardant filler of the class that evolve substantial amounts of bound water on heating at temperatures above a value Td that lies in the range 120 DEG -250 DEG  C.; a compatible ethyelene copolymer base in which the filler is dispersed; a hydrolysable unsaturated silane; and a free-radical grafting initiator having a half-life of less than 10 minutes at a temperature 25 DEG  C. below Td.
Patent FI-874636-A0 (FI)
Inventor: MARCUS ILAN
IPC: D06M15/507
Filed: 1987-10-21
Abstract: Polyester fiberfill having spiral crimp that is randomly-arranged and entangled in the form of fiberballs with binder fibers, preferably with a minimum of hairs extending from the surface of the fiberballs, so as to be air-transportable on account of the low cohesion between the balls. A process for making such fiberballs by repeatedly air-tumbling small tufts of such fiberfill/binder/blend against the wall of a vessel. Improved bonded batts or molded articles or other bonded articles obtained by bonding such fiberballs.
Patent FI-900533-A0 (FI)
Inventor: GROS WILLIAM A
IPC: C09J11/00
Filed: 1990-02-02
Abstract: The invention is a die attach adhesive composition comprising a homogeneous blend of an organopolysiloxane-bridged bisbenzocyclobutene monomer, an organosilane adhesion aid, and a finely divided electrically conductive metal. The composition is easy to apply, exhibits good adhesive strength and thermal stability at high temperatures, and does not require solvents, initiators, or curing agents. Weight loss on cure is minimal.
Patent FI-910106-A0 (FI)
Inventor: WUNDER RAINER
IPC: B01D53/34
Filed: 1991-01-09
Abstract: In a process for the removal of ammonia, and, if required, dust, from waste gases which arise in the production of fertilizers, the waste gases are treated in an absorption zone with a circulated ammonium nitrate solution. The ammonium nitrate solution has a temperature theta  of 20 to 100 DEG C and, at the entry to the absorption zone, a pH of at least a value given by the following formula <IMAGE> in which Y denotes the ammonia concentration of the gas to be treated in mg/m<3)<S.T.P.).
Patent FI-911625-A0 (FI)
Inventor: GAISFORD SCOTT G
IPC: G01R27/04
Filed: 1991-04-04
Abstract: Radio frequency bridge techniques are used to parameterize the complex dielectric properties of solids, liquids, gasses and mixtures thereof. This parameterization is performed in an electrically isolated, physically open structure which allows continuous or batch monitoring of the materials and their mixtures. A method and apparatus are provided for measuring the composition of mutlicomponent process streams flowing in pipes or ducts. The method uses the pipe in which the mixture flows as a waveguide in which propagating radio frequency electromagnetic energy is induced through dielectric loaded apertures. The dielectric measurement is performed in an electrically isolated, flow through test section which induces constructive or destructive interference patterns at characteristics frequencies. The characteristic frequency determines the dielectric constant of the mixture. The dielectric properties are used in turn to determine mixture composition. A density measurement is also provided for three comiponent strams such as oil, water, and gas. Temperature and pressure measurements are made to correct for temperature and pressure induced variations in calibrated component impedance and density values.
Patent FI-913351-A0 (FI)
Inventor: GRETHER PAUL
IPC: E06B3/66
Filed: 1991-07-10
Abstract: In the edge bond for the panes (1, 2) of the multiple glass unit there is provided a spacer profile (3), which preferably consists of a plastic material having poor heat conducting properties. It is stuck between the panes by means of a contact adhesive (4). A strip (5) of a thin, flat metal foil is attached around the spacer profile on the outside as a water vapour barrier. In marginal areas adjacent to the panes, the outer side (3.1) of the spacer profile is designed to be set back from the flat metal strip in such a way that peripheral chambers (6) are produced. These chambers are filled with an adhesive which is impermeable to water vapour, preferably a butyl adhesive. 
<IMAGE>
Patent FI-920971-A0 (FI)
Inventor: HAMMER KLAUS-DIETER
IPC: A22C13/00
Filed: 1992-03-05
Abstract: A tubular foodstuff casing based on cellulose is described, having a coating present on its internal surface for improving the ability to peel off the casing from the filling. The coating contains lecithin and alginate and/or chitosan and/or casein.
Patent FI-922806-A0 (FI)
Inventor: ASK ANNA-LENA
IPC: C07D211/64
Filed: 1992-06-17
Abstract: Compounds of the formula IV for use as local anaesthetica and analgetica, as well as a method for their preparation, their pharmaceutical preparations and their use.    <IMAGE>  IV
Patent FI-941015-A0 (FI)
Inventor: ZARLING DAVID A
IPC: C12Q1/68
Filed: 1994-03-03
Abstract: PCT No. PCT/JP92/01128 Sec. 371 Date Jun. 3, 1994 Sec. 102(e) Date Jun. 3, 1994 PCT Filed Sep. 3, 1992 PCT Pub. No. WO93/05177 PCT Pub. Date Mar. 18, 1993A method of identifying the presence of a known target sequence in nucleic acid contained in a fixed cellular or subcellular biological structure. By adding a stable, reporter-labeled RecA/single-stranded probe complex to the cellular or subcellular structure, the target sequence can be effectively labeled by in situ hybridization, allowing the target sequence to be visualized histologically and microscopically or detected by in situ cytometry or cell sorting flow techniques.
Patent FI-941133-A0 (FI)
Inventor: MUTCHNICK MILTON
IPC: A61K38/16
Filed: 1994-03-10
Abstract: Method comprises administering immune system-potentiating dose of at least one thymosin or an immune system-potentiating thymosin fragment. The thymosin is pref. Thymosin Fraction Five or Thymosin alpha-1.
Patent FI-950759-A0 (FI)
Inventor: CATT MICHAEL
IPC: G01N33/493
Filed: 1995-02-20
Abstract: A method of monitoring the status of a current ovulation cycle of an individual human female subject, involving testing of the body fluid concentration of an analyte of significance in relation to the status of the ovulation cycle, such as urinary E3G, during at least part of the pre-ovulation phase of the current ovulation cycle of the individual subject, and identification from the results of such testing an analyte concentration change indicative of imminent ovulation, relative to an analyte concentration reference value that has been adapted to the individual human subject on the basis of analyte concentration test data obtained from the individual human subject during one or more previous ovulation cycles. Preferably testing for said analyte concentration during the current ovulation cycle is commenced a plurality of days (preferably at least 5) following the onset of menses but at least 2 numerical days in advance of the earliest numerical day on which actual ovulation has occurred in one or more previous ovulation cycles in the same individual subject.
Patent FI-951026-A0 (FI)
Inventor: SCHREMMER ULF
IPC: A62C35/68
Filed: 1995-03-06
Abstract: The radial spray nozzle is built into a pipe conduit of the fire-fighting unit comprises a housing in which is formed a torsion mixt. chamber constituting a flow body. The flow body (3) is located in a flow housing (6) supported by a cover housing (11), which at the lower end has a cylindrical tube (12) with a cylindrical nozzle aperture (10). The flow housing in common with the cover housing forms an outer torsion mixt. chamber (13) and an annular gap (14) at a distance from the lower end of the tube (12). The cover housing is provided with one or more tangential and radially inclined holes (15) which end in the outer torsion mixt. chamber.
Patent FI-964345-A0 (FI)
Inventor: PETERZELL PAUL E
IPC: H04L27/22
Filed: 1996-10-28
Abstract: An automatic gain control (AGC) apparatus for a digital receiver is disclosed herein. The AGC apparatus includes an adjustable gain amplifier having an input port for receiving an input signal, a control port for receiving a gain control signal, and an output port for providing an output signal. The AGC apparatus further includes a measurement circuit for generating a received power signal based on the power of the output signal. A saturating integrator compares the received power signal to a reference signal and generates an gain control signal in response to a result of the comparison. The saturating integrator includes a decision circuit for enabling integration based on values of the received power signal, the reference signal, and the gain control signal. In a preferred implementation the utilization of an input limiter in conjunction with an analog to digital converter enables accommodation of an increased input signal dynamic range. Accordingly, the AGC apparatus is capable of being used in digital demodulation of FM signals. The AGC apparatus may also be employed within a dual mode receiver designed to process both FM and code division multiple access (CDMA) input signals.
Patent FI-970768-A0 (FI)
Inventor: SEDLACEK HANS-HARALD
IPC: A61K47/48
Filed: 1997-02-24
Abstract: PCT No. PCT/EP95/03370 Sec. 371 Date Apr. 18, 1997 Sec. 102(e) Date Apr. 18, 1997 PCT Filed Aug. 25, 1995 PCT Pub. No. WO96/06940 PCT Pub. Date Mar. 7, 1996A DNA sequence for the gene therapy of tumors is described. In its essential elements, the DNA sequence is composed of an activator sequence, a promoter module and a gene for the active substance. The activator sequence is activated, in a cell-specific manner, in proliferating endothelial cells or in cells which are adjacent to these endothelial cells. This activation is regulated by the promoter module in a cell cycle-specific manner. The active substance is an inhibitor of angiogenesis or a cytostatic or cytotoxic molecule. The DNA sequence is inserted into a viral or non-viral vector which is supplemented with a ligand which possesses affinity for the activated endothelial cell.
Patent FI-971380-A0 (FI)
Inventor: BAUMSTARK ROLAND
IPC: C08F6/00
Filed: 1997-04-03
Abstract: PCT No. PCT/EP95/03770 Sec. 371 Date Apr. 3, 1997 Sec. 102(e) Date Apr. 3, 1997 PCT Filed Sep. 23, 1995 PCT Pub. No. WO96/10588 PCT Pub. Date Apr. 11, 1996A process for the preparation of an aqueous polymer emulsion, in which an aqueous emulsion of a polymer which contains at least one chemically bonded monomer having at least one ethylenically unsaturated group is produced in a manner known per se so that the total content of free monomers having at least one ethylenically unsaturated double bond, ie. monomers of this type which are not chemically bonded, in the aqueous polymer emulsion is from >0 to </=1% by weight, based on the polymer content of the aqueous polymer emulsion, and this residual monomer content is then reduced by the action of a free radical redox initiator system comprising at least one oxidizing agent and at least one reducing agent, wherein the redox initiator system comprises, as the reducing agent, one which is present, in aqueous solution, in at least two tautomeric forms in equilibrium with one another (for example aminoiminomethanesulfinic acid and/or the salts thereof).
Patent AP-0202538-A0 (AP)
Title: Inhibitors of interleukin -1b converting enzyme.
Inventor: BATCHELOR MARK J
IPC: A61K38/07
Filed: 1996-12-20
Abstract: The present invention relates to novel classes of compounds which are inhibitors of interleukin -1b converting enzyme. The ice inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compunds. The compounds and pharmaceutical compositions f this invention are particularly well suited for inhibiting ice activity and consequently, may be advantageously used as agents against il-1-, apoptosis-, igif-, and ifn-y-mediated diseases, infamatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ice activity, for treating interleukin-1-, apoptosis-,igif- and ifn-y-mediated diseases and decreasing igif and ifn-y- production using the compounds and compositions of this invention. This invention also relates to methods for preparing n-acylamino compounds
Patent IL-57384-A0 (IL)
Title: Imidazole derivatives process for their preparation and pharmaceutical preparations containing them
IPC: C07D233/84
Filed: 1979-05-23
Abstract: Imidazole derivatives of the formula   <IMAGE>   wherein Ar1 and Ar2 are each phenyl; phenyl substituted by halogen, C1-4 alkyl, C1-4 alkoxy or C2-6 dialkylamino; pyridyl; furyl; or thienyl; with the proviso that Ar1 and Ar2 are not both unsubstituted phenyl; R1 is hydrogen, C1-4 alkyl or C1-4 alkyl substituted by hydroxy, C1-4 alkoxy or C1-6 alkanoyloxy; n is 0, 1 or 2; and Z is a C2-6-alkyl or -alkenyl residue substituted by one or two of hydroxy, C1-4 alkoxy, C2-8 alkylenedioxy, C1-6 alkanoyloxy or benzoyloxy, or by one alkoxycarbonyl group; and the salts thereof with physiologically acceptable acids, possess valuable pharmacological properties.
Patent IL-67198-A0 (IL)
Title: Azolyl-alkenones and-alkenols,their preparation and their use as plant-growth regulators and fungicides
IPC: C07D233/54
Filed: 1982-11-08
Abstract: 1. Azolyl-alkenones and -ols of the formula  see diagramm : EP0079006,P19,F1  in which R**1 represents the grouping  see diagramm : EP0079006,P19,F2  in which Z**1 and Z**2 are identical or different and represent hydrogen, halogen or alkyl with 1 to 4 carbon atoms, and, furthermore, R**1 represents phenyl which can be mono- or polysubstituted by identical or different substituents selected from halogen, alkyl with 1 to 4 carbon atoms, alkoxy and alkylthio each with 1 to 4 carbon atoms, alkyl- and dialkylamino each with 1 to 4 carbon atoms in each alkyl part, and also halogenoalkyl, halogenoalkoxy and halogenoalkylthio each with 1 to 2 carbon atoms and 1 to 5 identical or different halogen atoms, phenyl and/or phenoxy, it being possible for the two last-mentioned radicals in turn to be substituted by halogen and/or alkyl with 1 to 2 carbon atoms, R**2 represents straight-chain or branched alkyl with 1 to 12 carbon atoms, and also phenyl which can be mono- or polysubstituted by identical or different substitutents selected from halogen, alkyl with 1 to 4 carbon atoms, alkoxy and alkylthio each with 1 to 4 carbon atoms, alkyl- and dialkylamino each with 1 to 4 carbon atoms in each alkyl part, and also halogenoalkyl, halogenoalkoxy and halogenoalkylthio each with 1 to 2 carbon atoms and 1 to 5 identical or different halogen atoms, phenyl and/or phenoxy, it being possible for the two last-mentioned radicals in turn to be substituted by halogen and/or alkyl with 1 to 2 carbon atoms, or R**2 represents cycloalkyl which has 3 to 7 carbon atoms and is optionally substituted by halogen and/or alkyl with 1 to 4 carbon atoms or cycloalkylalkyl which has 3 to 7 carbon atoms in the cycloalkyl part and 1 to 2 carbon atoms in the alkyl part and is optionally substituted by halogen and/or alkyl with 1 to 4 carbon atoms, X represents the CO or CH(OH) group and Y represents a nitrogen atom or the CH group, and acid addition salts and metal salt complexes thereof.
Patent IL-69174-A0 (IL)
Title: Antibacterial penem derivatives
IPC: C07D499/897
Filed: 1983-07-06
Abstract: The present invention relates to certain penem derivatives of the general formula Iin which R represents a hydrogen atom or a carboxyl esterifying group, R<sup>1</sup> represents certain unsubstituted and substituted aromatic and heterocyclic groups, and R<sup>2</sup> represents a hydrogen atom, an unsubstituted or substituted alkyl or aryl group.The compound of formula I and salts thereof may be used in the treatment of bacterial infections in man and other animals.