baber/WOPTO huggingface dataset:
Patent CA-2414938-A1 (CA)
Title: Combinations of ssri and estrogenic agents
Inventor: JENKINS SIMON NICHOLAS
IPC: A61K31/445
Filed: 2001-06-29
Abstract: This invention comprises methods of treating depression, anxiety, generalized anxiety disorder (GAD), hot flush, post partum depression, premenstrual syndrome, obesity, obsessive compulsive disorder, post-traumatic stress disorder, social phobia, disruptive behavior disorders, impulse control disorders, borderline personality disorder, chronic fatigue disorder, premature ejaculation, pain, attention deficit disorders, with and without hyperactivity, Gilles de la Tourette syndrome, bulimia nervosa, or Shy Drager Syndrome comprising administration of a selective serotonin reuptake inhibitor and compound of the formula (I) or (II): wherein Z is a moiety selected from the group of: wherein: R¿1? is selected frm H, OH or the C¿1?-C¿12? esters or C¿1?-C¿12? alkyl ehers thereof, benzyloxy, or halogen; or C¿1?-C¿4? halogenated ethers including trifluoromethyl ether and trichloromethyl ether; R¿2?, R¿3?, R¿4?, R¿5?, and R¿6? are H, OH or C¿1?-C¿12? esters or C¿1?-C¿12? alkyl ethers thereof, halogens, or C¿1?-C¿4? halogenated ethers, cyano, C¿1?-C¿6? alkyl, or trifluoromethyl, with the proviso that, when R¿1? is H, R¿2? is not OH; Y is as defined; or a pharmaceutically acceptable salt thereof.
Patent CA-2417959-A1 (CA)
Inventor: KELLER CYRIL N
IPC: B60P1/00
Filed: 2003-01-31
Abstract: A pull-out load platform truck cargo beds. The load platform has a frame with a base, a plurality of outriggers that extend therefrom, and a pair of rails that are aligned with the base. The outriggers and the rails are adjustable and have ends that are configured and arranged to engage surfaces of a truck body in a non-invasive manner, so that when the load platform is installed in a cargo bed of a truck, the base is prevented from moving relative thereto. A deck, onto which cargo may be placed, is operatively connected to the frame and movable relative thereto, preferably in a constrained manner. When the deck is pulled out relative to the frame so that it extends partially beyond the end of the base in a cantilever fashion, the deck is prevented from tipping by the operative connection between the frame and the deck.
Patent CA-2418793-A1 (CA)
Title: Pharmaceutical composition comprising an analgesic peptide
Inventor: PRIMOR NAFTALI
IPC: C07K5/097
Filed: 2001-08-06
Abstract: A pharmaceutical composition for topical administration comprising an analgesic effective amount of a peptide comprising L-amino acids of the formula (I): pGLU-X-Y-Z M (I) and a pharmaceutically acceptable excipient. X  is an amino acid selected from the group consisting of GLY, VAL, GLU, ASP, SER, ALA, ASN, GLN, ILE, LEU, PRO, LYS and ARG, Y is TRP or THR, and Z is an y L-amino acid, or Z is null. When Z is any L-amino acid, one but not both of Y and Z is TRP, and when Z is null, Y = TRP. An alkyl group may be attached to  an amino acid of the peptide. Also disclosed are the peptide, the preparatio n of the pharmaceutical composition and a topical method of treating or preventing pain in a mammal.
Patent CA-2419866-A1 (CA)
Title: Mass spectrometers and methods of mass spectrometry
Inventor: BATEMAN ROBERT HAROLD
IPC: H01J49/42
Filed: 2001-11-29
Abstract: An ion guide 15;15' is disclosed comprising a plurality of electrodes 15a,15b each having apertures which are preferably circular and substantially the same size. The ion guide 15;15' is preferably maintained in a vacuum chamber at a relatively high pressure.
Patent CA-2423532-A1 (CA)
Title: Dispositif de reduction d'un coussin anal dans le traitement d'une maladie hemorroidale mineure
Inventor: LEE SIN HANG
IPC: A61F5/00
Filed: 2001-08-14
Abstract: Cette invention concerne un nouveau dispositif et un procédé de traitement des hémorroïdes. Le dispositif présente une forme sensiblement cylindrique et, au moins sur une partie, un diamètre compris entre environ 5 et 30 mm. Le dispositif s'insère dans un canal anal de manière à se positionner contre au moins un coussin anal déplacé. Il y est ensuite maintenu pendant une durée suffisante pour effectuer la réduction du coussin anal déplacé.
Patent CA-2424660-A1 (CA)
Inventor: CRUTTENDEN GEOFFREY JOSEPH
IPC: B41F17/36
Filed: 1997-03-20
Abstract: This invention relates to an apparatus for producing image bearing filled soft capsules which includes positively driven comprises guide rollers for directing the gelatin ribbons from casting drums to an encapsulation station. Along the path of at least one ribbon is a transfer station at which images are applied to the ribbon. The images are applied in a pattern which corresponds to the pattern of capsules formed from the ribbon at the encapsulation station. Both the rollers at the encapsulation station, and the support roller at or adjacent the transfer station are positively driven and a control system ensures that the peripheral speed of the support roller in the transfer station is the same as the speed of the ribbon into and through the encapsulation station.     The drive motor for the respective support roller at the transfer station is preferably a stepping motor which is adjustable to advance or retard relative to the ribbon speed at the encapsulation station. Sensors are also included to positively monitor the alignment of ribbon within the encapsulation process. Provision is also made monitoring the lateral positioning of images on the ribbon and for shifting the ribbon to accommodate any lateral misalignment.
Patent CA-2426163-A1 (CA)
Title: Identification and characterization of an anthocyanin mutant (ant1) in tomato
Inventor: LIU ALEX
IPC: C12N15/09
Filed: 2001-10-29
Abstract: The present invention is directed to a novel plant phenotype, designated Anthocyanin 1 (ANT1), a nucleic acid sequence expressed in plants demonstrating the ANT1 phenotype and the corresponding amino acid sequence.  Also provided are plant cells that exhibit modified ANT1 expression.
Patent CA-2427188-A1 (CA)
Inventor: HOMMA HOTAKA
IPC: H01M8/02
Filed: 2003-04-29
Abstract: The present invention provides a low-contact-resistance interface structure between a separator and a carbon material for a fuel cell, a carbon material and a separator used in the interface structure, and a production method for a stainless steel separator for a fuel cell. The present invention is a low-contact-resistance interface structure between a separator and a carbon material for a fuel cell, characterized by having a titanium nitride layer 0.1 to 200 µm in thickness between the stainless steel separator and the carbon material contacting therewith. Further, the present invention is a method for producing a stainless steel separator incorporated in the above interface structure for a fuel cell, characterized by forming a titanium nitride layer 0.1 to 200 µm in thickness on one or both surfaces of a stainless steel containing, in mass, C: 0.0005 to 0.03%, Si: 0.01 to 2%, Mn: 0.01 to 2.5%, S: 0.01% or less, P: 0.03% or less, Cr: 13 to 30%, and Ti: 0.05 to 5%, with the balance consisting of Fe and unavoidable impurities, by applying a nitriding treatment to the stainless steel, in an atmosphere gas containing nitrogen, after the stainless steel is formed into a prescribed shape.
Patent CA-2429378-A1 (CA)
Inventor: RENDRI YADAGIRI
IPC: C07D249/08
Filed: 2001-10-18
Abstract: An improved process is provided for preparing water-soluble prodrugs of triazole antifungal compounds containing a secondary or tertiary hydroxyl group. More particularly, the improved process is directed toward preparation of water-soluble triazole antifungal compounds having the general formula (I) wherein A is the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group and R and R1 are as defined in the specification.
Patent CA-2429745-A1 (CA)
Inventor: JACOBS PAUL E
IPC: H04N/
Filed: 1994-11-15
Abstract: System and method for minimizing data bottlenecks in Low Data Rate Networks (LDRNs) that communicate facsimile transmissions. An LDRN is a facsimile network having a transmission data rate less than the data rate of the FAX machines serviced by the network. The system and method can be implemented in any type of LDRN, including analog and digital wired LDRNs, as well as analog and digital wireless (e. g., cellular) LDRNs. The system and method involve processing the facsimile transmissions in order to make the data rates of the LDRN and the FAX machines compatible, thereby minimizing any potential facsimile data bottlenecks that may occur in the LDRN due to its slower data rate.
Patent CA-2431783-A1 (CA)
Title: Desintegrateur d'echantillons biologiques
Inventor: ROGGERO GIANMARCO
IPC: B02C19/08
Filed: 2001-12-05
Abstract: L'invention porte sur un désintégrateur servant en particulier à la désintégration d'échantillons biologiques utilisés pour la détection de l'encéphalopathie bovine spongiforme et comportant: un récipient (2) en forme de coupe recevant les tissus à désintégrer; un arbre (26) tournant dans le récipient (2), monté sur des paliers à billes (30, 34), muni à son extrémité intérieure au récipient d'une lame déchiqueteuse (28), et à son extrémité extérieure au récipient d'un moyen (36) de prise avec un moteur. Ledit désintégrateur est fait pour s'intégrer à un appareil automatique comportant: au moins un support (54) muni de plusieurs logements pour recevoir des récipients; une station de désintégration (50) comprenant au moins un moteur (52) dont l'arbre (55) peut se coupler au moyen (36) de prise de l'arbre (26), ledit moteur pouvant passer d'une position d'accouplement à une position de désaccouplement avec ledit arbre (26); et un convoyeur (66, 68 et 78) de transport du susdit support (54) vers la station de désintégration.
Patent CA-2432120-A1 (CA)
Title: Enhanced directory assistance system
Inventor: BLAKENEY JOHN
IPC: H04W4/029
Filed: 2001-09-17
Abstract: The present invention provides for an enhanced directory assistance system (2) for providing directions information to a plurality of callers (4). The system is comprised of a telephone switch (12) for receiving calls from a plurality of callers (4) desiring to receive directions, an automatic location system configured to provide the location from the callers (4) during a call session to the telephone switch (12); and an enhanced services direction module (21) configured to receive destination and starting location information provided by the caller (4) and further configured to provide directions to the caller (4) based on the provided information.
Patent CA-2432270-A1 (CA)
Title: Injection-molding nozzle system, injection-molding tool and method for producing injection-molded parts
Inventor: RESLHUBER CHRISTIAN
IPC: B29C45/28
Filed: 2003-06-13
Abstract: The present invention relates to an injection-molding nozzle system for injection- molding systems for plastic materials which is equipped with a needle sealing system and is suitable both for different cavities as well as for plastic materials of different viscosities, with the injection-molding nozzle comprising a temperable nozzle body with nozzle tip comprising an outlet opening anal an inlet opening for the plastic mass, as well as a needle which is arranged in the nozzle body and is displaceable in an axially longitudinal manner and with an actuating apparatus for actuating the needle which is axially displaceable in the nozzle body in the longitudinal direction. The opening stroke of the needle which is axially displaceable in the longitudinal direction can be adjusted by way of a stroke limiter, and the needle tip comprises at least one notch for the pass-through of the injection-molding mass in its transitional region to the needle shaft, The needle shaft is thereby in continual contact with a needle guide region of the nozzle tip.
Patent CA-2433972-A1 (CA)
Inventor: YIM RONALD TAK YAN
IPC: G01V3/08
Filed: 2003-06-27
Abstract: A device for locating an object behind a wall lining includes a housing having a front portion adapted to fit substantially in the palm of a users hand. Operating switches are located in juxtaposition the grip portion so as to be operable by the user without substantially altering a grip on the housing. The device also includes a sensor comprising a first capacitor plate and a pair of second capacitor plates. The capacitor plates are arranged vertically, and calibrated by a Pulse Width Modulator and integrator. Operating electronics are incorporated into an Application Specific Integrated Circuit.
Patent CA-2435937-A1 (CA)
Title: Rope game device
Inventor: KOHLER KARL-HEINZ
IPC: A63B9/00
Filed: 2002-01-31
Abstract: Known climbing frames comprising a support frame in which a rope net is rigged up are not very attractive as individual playing devices as there is no considerable 3-dimensional net volume, and the device cannot be combined by modular construction to form larger units. According to the present embodiment, the support frame consists of at least one pentagonal frame element, a separate rope net being fixed inside each frame element. The frame elements can thus be assembled in a modular manner to form complex 3-dimensional structures.
Patent CA-2436696-A1 (CA)
Inventor: RAY KYLE A
IPC: G10K11/162
Filed: 2003-08-08
Abstract: A multiple layer, thermoformable acoustic sheet material useful for manufacturing acoustic absorption, acoustic barrier and/or vibration damping components includes a barrier layer of synthetic fibers having an area weight of from about 40 grams per square foot to about 100 grams per square foot, and an absorber layer of vertically-lapped synthetic fibers, natural fibers or a combination of synthetic and natural fibers. The thermoformable acoustic sheet materials may include additional layers, with certain embodiments including an impermeable polymer film layer disposed between the barrier layer and the absorber layer.
Patent CA-2437150-A1 (CA)
Title: Ph-sensitive mucoadhesive film-forming gels and wax-film composites
Inventor: MUMPER RUSSELL
IPC: A61K9/00
Filed: 2001-12-27
Abstract: The present invention relates to pH-sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules of interest, namely active pharmaceuticals. The gels comprise a pharmaceutically acceptable pH-sensitive polymer that responds to a lowering of pH by precipitating into films when in contact with the skin or mucosal surface. The films also comprise an adhesive polymer that allows the film to remain in contact with the tissue for an extended period of time. The wax-film composites comprise a bi-layer film having both the said pH-sensitive mucoadhesive layer to promote strong adherence to the skin and mucosal surfaces as well as a specially bonded wax layer intended to extend the adherence of the film to tissues for a prolonged period of time. The invention also relates to the use of said pH-sensitive film-forming gels and wax-film composites to deliver molecules of interest, such as small molecules, peptides, proteins, and nucleic acids either locally to act at the site of administration or for the absorption of said molecules of interest across biological membranes into the systemic circulation.
Patent CA-2437423-A1 (CA)
Inventor: WALDER KEN
IPC: A61K48/00
Filed: 2002-02-05
Abstract: L'invention porte sur une molécule d'acide nucléique isolée comprenant une séquence de nucléotides codant ou complémentaire d'une séquence codant une molécule ou son dérivé ou son homologue. La molécule d'acide nucléique étant exprimée de manière plus importante dans un tissu d'hypothalamus et/ou un tissu musculaire chez les animaux obèses par rapport aux animaux minces ou chez les animaux affouragés par rapport aux animaux suivant un régime. L'invention porte également sur des séquences d'acide nucléique et vise à utiliser les produits d'expression desdits acides nucléiques comme modulateurs et/ou comme régulateurs des processus physiologiques associés à l'obésité, à l'anorexie, au maintien du poids, au développement musculaire déséquilibré, au diabète et/ou aux niveaux d'énergie métabolique.
Patent CA-2438339-A1 (CA)
Title: Use of buprenorphine for treatment of urinary incontinence
Inventor: BARTHOLOMAEUS JOHANNES
IPC: A61K31/31
Filed: 2002-02-18
Abstract: The invention relates to the utilization of buprenorphine in the production of a medicament for the treatment of increased urinary urgency, urinary frequency and/or urinary incontinence and to the corresponding medicaments and method for the treatment of urinary urgency, urinary frequency and/or urinary incontinence.
Patent CA-2440854-A1 (CA)
Title: Subcutaneous analyte sensor
Inventor: ESSENPREIS MATTHIAS
IPC: G01N21/41
Filed: 2002-03-18
Abstract: Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is impermeable to background species in the biological matrix. A refractive element is positioned in the cavity. A light source transmits light of a first intensity onto the refractive element, and a light detector receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.
Patent CA-2443261-A1 (CA)
Title: Colorable elastomeric composition
Inventor: WADDELL WALTER H
IPC: B60C1/00
Filed: 2001-10-16
Abstract: Transparent and colorable elastomeric compositions are provided. The transparent elastomeric compositions can be covulcanized with rubbers such as polybutadiene, polyisoprene, styrene-butadiene rubber, styrene-isoprene-butadiene rubber, isoprene-butadiene rubber, or natural rubber and polybutene processing oil. The colorable rubber compositions have sufficient properties to function as a reinforcing member in a shoe sole or automobile tire.  Preferably, both the transparent and colorable elastomeric compositions include at least one copolymer of a C4 to C7 isoolefin and ap-methylstyrene, silica and a high cispolybutadiene rubber._
Patent CA-2444234-A1 (CA)
Title: Adhesif monobloc a faibles emissions
Inventor: RAIDY JOHN EDMUND JR
IPC: C08L23/00
Filed: 2002-04-19
Abstract: Cette invention se rapporte à une composition d'adhésif qui peut être formulée de façon à présenter une faible émission ou pour ainsi dire aucune émission de composés organiques volatils (VOC). De tels adhésifs peuvent être formulés sous la forme d'adhésifs réactifs réticulés, monoblocs et à forte teneur en matières solides. On peut obtenir un tel adhésif en utilisant des réactions amide-ester-acrylate ou des réactions avec d'autres polymères carboxylés. Ces compositions d'adhésifs peuvent contenir des huiles, telles que diverses huiles siccatives et des polymères, copolymères et acides gras à action similaire. Ces adhésifs peuvent également contenir diverses résines d'hydrocarbures, en particulier des hydrocarbures réticulables ayant un point de fusion compris entre 70· C et 140· C. Il est également avantageux d'y inclure des agents de réticulation, tels que des substances ayant des groupes oxazoline pendants. Divers autres ingrédients de mélange, d'écoulement et de manutention peuvent en outre être inclus.
Patent CA-2444802-A1 (CA)
Inventor: STAFFA ALFREDO
IPC: C12P13/00
Filed: 2002-05-21
Abstract: Five protein families cooperate to form the warhead structure that characterizes enediyne compounds, both chromoprotein enediynes and non-chromoprotein enediynes. The protein families include a polyketide synthase and thioesterase protein which form a polyketide synthase catalytic complex involved in warhead formation in enediynes. Genes encoding a member of each of the five protein families are found in all enediyne biosynthetic loci. The genes and proteins may be used in genetic engineering applications to design new enediyne compounds and in methods to identify new enediyne biosynthetic loci.
Patent CA-2446343-A1 (CA)
Title: Method of repairing a stationary shroud of a gas turbine engine using laser cladding
Inventor: MILLER MATTHEW NICKLUS
IPC: B23K26/34
Filed: 2003-10-23
Abstract: A stationary shroud (24) of a gas turbine engine made of a base metal is repaired by removing any damaged material from a flow-path region (40) of the stationary shroud (24) to leave an initially exposed base-metal flow-path surface (70); and applying a base-metal restoration (72) overlying the initially exposed flow-path surface (70).  The base-metal restoration (72) is applied by furnishing a source of a structural material that is compatible with the base metal, in a form such as a powder or a wire, and depositing the source of the structural material overlying the initially exposed base-metal flow-path surface (70) of the stationary shroud (24) by laser cladding to form a repaired base-metal flow-path surface (76). An environmentally resistant rub coating (78) may be applied overlying the base-metal restoration (72).
Patent CA-2447530-A1 (CA)
Title: Method for preparing an optical glass for edge grinding, resulting glass and method for edge grinding such a glass
Inventor: LACAN PASCALE
IPC: G02B1/11
Filed: 2002-05-17
Abstract: A method that allows trimming glass comprising a hydrophobic and/or oil-repellent surface coating, where a temporary protective layer is coated on the surface of said glass and the temporary protective layer imparts to the glass a surface energy of at least 15 mJ/m2.
Patent CA-2447674-A1 (CA)
Inventor: HOISCHEN DOROTHEE
IPC: A01N43/824
Filed: 2002-05-08
Abstract: The invention relates to benzoylpyrazoles of general formula (I), in which Q , R1, R2, R3, R4, R5, Y and Z have the meaning given in the description, metho ds and intermediates in the production thereof and use thereof as herbicides.</ SDOAB>
Patent CA-2447984-A1 (CA)
Inventor: SOWDEN HARRY S
IPC: A61K9/00
Filed: 2002-09-28
Abstract: A dosage form comprises an active ingredient, a core having an outer surface and a first shape and a shell having outer and inner surfaces and a second shape, in which the shell surrounds at least a portion of the core, and the first and second shapes are substantially different. In one embodiment the shell comprises at least about 80% of a flowable material selected from the group consisting of film formers, gelling polymers, thermoplastic materials, low melting hydrophobic materials, non-crystallizable sugars, non- crystallizable sugar-alcohols, and mixtures thereof. In another embodiment t he shell is substantially free of pores having a diameter of 0.5 to 5.0 microns . In another embodiment, the core and shell each having a different number of planes of symmetry with respect to the same reference axis. In another embodiment, the distance from the core outer surface to the shell outer surface is different at two different points located on the core outer surfa ce and the difference is greater than about 125 microns. Either the core, the shell, or a combination thereof may contain at least one active ingredient. The core and shell may each be molded or compressed. The core may also comprise an insert which may contain at least one active ingredient. The sha pe of the core may be chosen so asto permit modified release of active material in the core upon breach of the shell or provides a modified release profile for the active material in the core.
Patent CA-2448917-A1 (CA)
Inventor: STUDER MARTIN
IPC: C07C67/307
Filed: 2002-07-02
Abstract: Cette invention concerne des procédés de synthèse pour la préparation de dérivés de statine, qui font intervenir un intermédiaire clé de formule (I), dans laquelle X est halogène, acyloxy, hydrocarbyloxy activé, hydrocarbylthio activé ou N(CH¿3?)OCH¿3?, R¿a? est un groupe protecteur hydroxy, et R¿b? est un groupe protecteur carboxy. L'invention concerne également, comme pour le composé de formule (I), d'autres intermédiaires ainsi que leur procédés de préparation par acylation Friedel-Crafts.