baber/WOPTO huggingface dataset:
Patent CA-2258243-A1 (CA)
Title: 4,7-dichlororhodamine dyes
Inventor: SPURGEON SANDRA L
IPC: C07H19/14
Filed: 1997-05-21
Abstract: A class of 4,7-dichlororhodamine compounds useful as fluorescent dyes are disclosed having structure formula (I) wherein R1-R6 are hydrogen, fluorine, chlorine, lower alkyl, lower alkene, lower alkyne, sulfonate, sulfone, amino, amido, nitrile, lower alkoxy, linking group, or combinations thereof, or, when taken together, R1 and R6 is benzo, or, when taken together, R4 and R5 is benzo; Y1-Y4 are hydrogen or lower alkyl, or, when taken together, Y1 and R2 is propano and Y2 and R1 is propano, or, when taken together, Y3 and R3 is propano and Y4 and R4 is propano; and X1-X3 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alkyl, carboxylate, sulfonic acid, -CH2OH, and a linking group. In another aspect, the invention includes reagents labeled with the 4,7-dichlororhodamine dye compounds, including deoxynucleotides, dideoxynucleotides, and polynucleotides. In an additional aspect, the invention includes methods utilizing such dye compounds and reagents including dideoxy polynucleotide sequencing and fragment analysis methods.
Patent CA-2260186-A1 (CA)
Inventor: PLANKENHORN WOLFGANG
IPC: B24D15/06
Filed: 1997-07-11
Abstract: A device for sharpening blades has a hard metal cutting plate (7), known per se, secured to an ergonomically shaped handle (1). A bead (6) is provided to reduce the risk of accidents.
Patent CA-2264220-A1 (CA)
Title: Indolinone combinatorial libraries and related products and methods for the treatment of disease
Inventor: MCMAHON GERALD
IPC: A61K31/40
Filed: 1997-08-20
Abstract: The present invention relates to organic molecules capable of modulating, regulating and/or inhibiting protein kinase signal transduction. Such compounds are useful for the treatment of diseases related to unregulated protein kinase signal transduction, including cell proliferative diseases such as cancer, atherosclerosis, arthritis and restenosis and metabolic diseases such as diabetes. The present invention features indolinone compounds that potently inhibit protein kinases and related products and methods. Inhibitors specific to the FLK protein kinase can be obtained by adding chemical substituents to the 3-¢(indole-3-yl)methylene!-2-indolinone, in particular at the 1' position of the indole ring. Indolinone compounds that specifically inhibit the FLK and platelet derived growth factor protein kinases can harbor a tetrahydroindole or cyclopentano-b-pyrrol moiety. Indolinone compounds that are modified with substituents, particularly at the 5 position of the oxindole ring, can effectively activate protein kinases. This invention also features novel hydrosoluble indolinone compounds that are tyrosine kinase inhibitors and related products and methods.
Patent CA-2264787-A1 (CA)
Title: Waterborne lubricant for the cold plastic working of metals
Inventor: KARUBE KENJI
IPC: B21C9/00
Filed: 1997-08-29
Abstract: A waterborne lubricant for the cold plastic working of metals that contains alkali metal salts of dimer(s) and/or trimer(s) of unsaturated fatty acids with from 10 to 24 carbon atoms per molecule has a lubrication performance at least as good as that of prior lubricants, even at generally lower lubricating film weights, has a long bath life, and generates little dust during cold plastic working operations. Even as little as 5 % of these salts of dimer(s) and/or trimer(s) of unsaturated fatty acids, when mixed with conventional alkali metal salts of saturated fatty acids with from 10-24 carbon atoms per molecule, can provide these benefits.
Patent CA-2265635-A1 (CA)
Title: Skin care compositions containing combinations of compounds for mimicking the effect on skin of retinoic acid
Inventor: ZHANG KELLY HUA
IPC: A61Q17/04
Filed: 1997-09-18
Abstract: Compounds which sufficiently inhibit LRAT or ARAT catalyzed esterification of retinol into inactive retinyl esters, have the same effect on keratinocytes as retinoic acid. Thus, effects of retinol or retinyl esters in combination with these compounds are analogous to treatment with retinoic acid.
Patent CA-2267447-A1 (CA)
Title: Apparatus, systems and methods for applying filling compound and water absorbing particles in a stranded conductor
Inventor: BRUYNELL TIMOTHY B
IPC: H01B13/32
Filed: 1999-03-30
Abstract: Apparatus and systems for applying filling compound, such as water blocking compound, and water absorbing powder to a core wire or wires of a stranded conductor or to subsequent layers of a stranded conductor, which are particularly suitable for use with a tubular strander, include a rotatable head, which may be positioned downstream of a wire strander. The core is drawn through a core passage where the filling compound is applied to the core and powder is applied to the filling compound. Strand through passages are provided through the rotatable head, for drawing the strand wires therethrough, without being coated. The strand wires are stranded about the core in a closing die. Preferably, the powder circulation circuit is a closed circuit, enabling recycling of the powder. The powder is preferably fluidized prior to its delivery to the applicator, and is withdrawn from the applicator under a slight vacuum. The rotatable head may include a filling compound applicator section and a powder applicator section, which are connected to each other so that they rotate together. Methods of applying filling compound and water absorbing powder are also described.
Patent CA-2268329-A1 (CA)
Title: Method of determining receiver locations in a common wave network
Inventor: LAUTERBACH THOMAS
IPC: H04H20/67
Filed: 1997-08-27
Abstract: A process for determining receiver locations in a simultaneous broadcasts network is proposed, this serving to significantly improve the positions of the receivers determined by the propagation time differential by analyzing the channel impulse response of the transmission channel.
Patent CA-2271944-A1 (CA)
Title: Formulation for electrically assisted delivery of lidocaine and epinephrine
Inventor: CHIN IVAN W
IPC: A61K33/04
Filed: 1997-11-03
Abstract: The invention relates to formulations for the electrically assisted transdermal delivery of lidocaine and epinephrine. The present invention further provides methods and devices for the electrically assisted delivery of local anesthetics, preferably lidocaine.
Patent CA-2272041-A1 (CA)
Title: Polyisobutanyl succinimides and fuel compositions containing the same
Inventor: CHERPECK RICHARD E
IPC: C10L1/2383
Filed: 1999-05-13
Abstract: A compound of the formula:   (see formula I) wherein R1 is a polyisobutanyl group derived from a highly reactive polyisobutene having an average molecular weight in the range of from about 500 to 5,000;      R2 is an alkylene group having from about 2 to 6 carbon atoms; and x is an integer from about 1 to 4.      The polyisobutanyl succinimides of the present invention are useful as fuel additives for the prevention and control of engine deposits.
Patent CA-2272260-A1 (CA)
Title: Thin, planar heat spreader
Inventor: THOMAS DANIEL LEE
IPC: H01L23/427
Filed: 1997-11-17
Abstract: A heat spreading apparatus (20) includes a first planar body (22) for attachment to a heat generating surface and a second planar body (21) connected to the first planar body (22) defining a void therebetween. The void contains a vaporizing fluid and includes a planar capillary path (50) and a non-capillary path (32).
Patent CA-2273004-A1 (CA)
Inventor: BOUZAT GILBERT
IPC: A62D3/33
Filed: 1997-11-25
Abstract: Procédé d'insolubilisation et de consolidation sous forme de boulettes de brasques usées provenant des cuves d'électrolyse pour la production d'aluminium comportant le broyage desdites brasques ainsi que leur mélange intime avec divers additifs pulvérulents réfractaires avant cuisson caractérisé en ce qu'après introduction: d'un premier additif destiné lors de la cuisson à fixer les métaux alcalins, et choisi dans le groupe des silicoaluminates, puis d'un second additif destiné lors de la cuisson, d'une part, à se combiner avec les composés fluorés d'imprégnation pour former de nouveaux composés stables et insolubles, d'autre part, par sa fraction excédentaire non combinée, à assurer la consolidation du mélange, et choisi dans le groupe des oxydes et sels de calcium et de préférence des ciments et mortiers calcaires, on effectue une mise en forme par agglomération sous forme de boulettes du mélange intime de vieilles brasques broyées avec lesdits premier et second additifs pulvérulents avant cuisson à une température comprise entre 700 ~C et 950 ~C.
Patent CA-2275367-A1 (CA)
Inventor: LEGRAND CHARLES GABRIEL
IPC: A23L29/00
Filed: 1997-12-23
Abstract: Utilisation de bactéries propioniques pour l'obtention d'une composition d'alimentation courante ou d'une composition diététique ou médicamenteuse absorbable susceptible de dégager des quantités physiologiquement significatives de monoxyde d'azote dans le tube digestif humain ou animal.
Patent CA-2276108-A1 (CA)
Title: Novel peptide, novel dna, and novel antibody
Inventor: NABESHIMA YOUICHI
IPC: A01K67/027
Filed: 1997-12-12
Abstract: The present invention relates to a polypeptide having an activity of suppressing aging; DNA encoding the polypeptide; a method for improving livestock, using the DNA; a recombinant DNA prepared by inserting the DNA  into a vector; a transformant harboring the recombinant;  a method for preparing the polypeptide of the present invention, using the transformant; an antibody which recognizes the polypeptide; a ligand for the polypeptide of the present invention; a compound inhibiting specific binding between the polypeptide and ligand of the present invention; a compound enhancing the expression of an aging-suppressing gene encoding the aging--suppressing polypeptide of the present invention; an oligonucleotide comprising a sequence of 10 to 50 nucleotides in the nucleotide sequence of the DNA; and a therapeutic agent for a syndrome resembling premature aging, a therapeutic agent for adult diseases or an aging-suppressing agent, using the same.
Patent CA-2276827-A1 (CA)
Title: Banquet table
Inventor: CHANG MEI-FANG
IPC: A47B3/087
Filed: 1999-07-05
Abstract: A banquet table including a table surface, upper frames fixedly installed on the bottom side of the table surface, and leg frames which are rotatably connected to the upper frames so as to allow the leg frames to be folded inward and toward the bottom side of the table surface. The table surface can also be formed by two sections for folding. The two-section banquet table also includes a pair of hinges for connecting the upper frames on each table section. The hinges are designed to include two facing pressure resisting sections so that when the table is extended, the pressure of the table is applied on the pressure resisting sections, instead of the connecting pin shafts.
Patent CA-2278300-A1 (CA)
Inventor: SMALLCOMB JOSEPH
IPC: H04L29/06
Filed: 1998-02-13
Abstract: Interactive internet (5) activities are a very popular means for gathering information for business, personal, medical, entertainment and other purposes.  Most internet interaction is asymmetrical in nature in that a client's (1) requests for information are much smaller (in data size) than the resulting information delivered by the server (7). Although the client/internet link (2, 11) is inherently asymmetrical, there remains a great deal of interaction and overhead required between the client (1) and the server (7) that increases the bandwidth needs for the client's upstream request channel (2, 3, 4). There are many advantages to reducing this upstream traffic volume and thereby making the internet interaction even more asymmetrical. Such compression (15) of request data could allow more clients (1, CP) to utilize a single upstream data path instead of separate paths.
Patent CA-2278448-A1 (CA)
Title: Information system
Inventor: MANNINGS ROBIN THOMAS
IPC: H04Q7/22
Filed: 1998-02-04
Abstract: An interactive information delivery system server (2), delivering text or other visual data to a display unit (3) is accessed by a user by means of his own telephone (6), through an interface unit (1). The interface unit (1) interprets key pad presses and/or voice commands, and in response to these it controls the server (2). This allows the expensive and vulnerably hardware 3/4 (which may be a conventional PC and modem) to be positioned in a secure location, but still be usable by members of the public. As the location of the display unit (3) (which may be a conventional PC and modem) may make audio output impractical, the interface unit (1) may pass an audio channel from the server (2) to the user's telephone (6). In response to appropriate commands from the telephone (6), it can also divert the call to a predefined call centre. The server (2) application scripts and control programs largely follow normal WWW Internet practice, except that the output from the server is to be transmitted to a destination (display unit 3) other than that from which the instructions arrive (the interface 2). The display unit (3), when in idle mode, displays a page or pages in the idle state, including a telephone number to dial in order to access information. This number will be specific to the display unit, allowing the interface unit (1) to identify which display unit the user wishes to use.
Patent CA-2283429-A1 (CA)
Inventor: ESKILDSEN CHRISTIAN
IPC: H05B6/12
Filed: 1998-03-13
Abstract: L'invention concerne un noyau de forme évasée destiné à un appareil de chauffage par induction présentant un excédent de matériau ferromagnétique disposé de manière à obtenir une augmentation du flux utile, notamment par la réduction de la réluctance près de la pièce polaire centrale et près de la partie de couronne du noyau.
Patent CA-2284259-A1 (CA)
Title: Laser modulation control method and apparatus
Inventor: LINK GARRY N
IPC: H01S5/0683
Filed: 1998-03-17
Abstract: Laser modulation control apparatus and methods which provide direct control of the transmitted optical extinction ratio of a semiconductor laser. A relatively low frequency and low amplitude pilot tone is superimposed on the signal used to drive the laser. Setting the amplitude of the pilot tone to a fixed fraction of the laser modulation current causes the transmitted optical power to vary a fixed fraction of the optical data amplitude at the pilot tone frequency. By using feedback to control the laser modulation current, the amplitude of the variation can be maintained at a desired value, which in turn maintains the transmitted optical data amplitude at a constant value, regardless of variations due to operating temperature or laser aging. A  separate control loop is employed to maintain the average optical power at a fixed value. Since the optical data amplitude and the average optical power remain constant, the optical extinction ratio is also constant. Alternate embodiments are disclosed.
Patent CA-2289095-A1 (CA)
Inventor: HUANG WENZHONG J
IPC: A61P25/28
Filed: 1998-04-28
Abstract: This invention provides a compound having formula (I) wherein R and R1 are each, independently, hydrogen or SO3-X+; X+ is alkali metal, alkaline earth metal, ammonium, alkylammonium containing 1-6 carbon atoms, or dialkylammonium containing 1-6 carbon atoms in each alkyl group, or trialkylammonium containing 1-6 carbon atoms in each alkyl group; with the proviso that R and R1 are not both hydrogen, which is useful as a progestational agent.
Patent CA-2289645-A1 (CA)
Inventor: KIM YOUNG KY
IPC: H04J13/00
Filed: 1999-03-31
Abstract: L'invention concerne un système de télécommunication AMCR émettant/recevant une information de commande pendant un service de communication vocal et/ou de données, par l'intermédiaire d'une voie de commande spécifique. La longueur de trame du message pour l'information de commande varie en fonction de la quantité d'information de commande. Le système de communication AMCR comprend une unité station de base et une unité terminal. L'unité station de base comprend un générateur (105) de voie pilote aller permettant de générer un signal pilote, un générateur (103) spécifique de voie de commande aller permettant de générer un message de commande pour une voie de commande spécifique aller, un générateur fondamental (111) de voie aller permettant de générer un signal vocal, et un générateur (113) complémentaire de voie aller permettant de générer des paquets de données. L'unité terminal comprend un générateur (153) de voie de commande retour spécifique permettant de générer un message de commande pour une voie de commande spécifique de retour, un générateur (155) de voie pilote de retour permettant de générer un signal pilote par addition d'un signal de régulation de puissance au signal pilote, un générateur (159) de voie fondamentale de retour permettant de générer un signal vocal, et un générateur (161) de voie complémentaire de retour permettant de générer des paquets de données.
Patent CA-2291650-A1 (CA)
Inventor: DIAZ PHILIPPE
IPC: A61K8/00
Filed: 1999-03-29
Abstract: L'invention concerne de nouveaux composés hétéroéthynylénés qui présentent comme formule générale (I), ainsi que l'utilisation de ces derniers dans des compositions pharmaceutiques destinées à un usage en médecine humaine ou vétérinaire (affections dermatologiques, rhumatismales, respiratoires, cardiovasculaires et ophtalmologiques notamment), ou bien encore dans des compositions cosmétiques.
Patent CA-2292718-A1 (CA)
Title: High speed analog-to-digital converter and digital-to-analog converter
Inventor: YEAP TET HIN
IPC: H03M1/66
Filed: 1999-12-20
Abstract: An high speed analog-to-digital converter, for converting an analog input signal (u(t)) with a maximum frequency (F max) to a digital output signal (x(n)) with an output sampling rate (F s) at least double the maximum frequency (F max) comprises a plurality of analog narrowband filters (F0-F M-1) for filtering the analog input signal (u(t)) to produce a corresponding plurality of narrowband signals (X0-X M-1). Each narrowband filter has a passband. The sum of the gains of the narrowband filters at any frequency within an operating frequency band of the plurality of narrowband filters is substantially unity. Each of a corresponding plurality of analog-to-digital converter units (AD0-AD M-1) comprises a sample-and-hold device (SH) and a quantizer (Q). The sample-and-hold devices are clocked by a corresponding plurality of clock signals (.PHI.0-.PHI.M-1), respectively, each of the plurality of clock signals having a frequency at least double the bandwidth of the corresponding narrowband filter and an integer division of said predetermined sampling rate. The converter also comprises sampling and summing circuitry for sampling the outputs of the analog-to-digital converter units sequentially at the predetermined sampling rate (Fs) and summing the resulting sampled signals to produce the digital output signal (x(n)). The frequencies of the plurality of clock signals, and their phase-displacements relative to the output sampling clock signal, are such that each sample of the analog-to-digital converter output signal corresponds to a sampling edge of a different one of the sample-and-hold clock signal.
Patent CA-2295689-A1 (CA)
Title: Apparatus and method for object based rate control in a coding system
Inventor: CHIANG TIHAO
IPC: G06T9/00
Filed: 1998-07-09
Abstract: A method and apparatus for selecting a quantizer scale for each object within a frame to optimize the coding rate are disclosed. A quantizer scale is selected for each region or "object" within each frame such that the target bit rate for the frame is achieved while maintaining a uniform visual quality over the entire frame.
Patent CA-2297189-A1 (CA)
Title: Process for the preparation of 1,3-diaza-spiro (4.4) non-1-en-4-one derivatives and 1-cyano-1-acylaminocyclopentane intermediates
Inventor: CSETRINE HARI ZSUZSANNA
IPC: C07D235/02
Filed: 1998-07-22
Abstract: Process for the preparation of compounds of formula (I) wherein R  means hydrogen atom, or C1-6 alkyl group or C7-12 aralkyl group or phenyl group, characterised in that a) the compound of formula (III) is reacted with a compound of formula (IV) wherein X means halogen atom or C1-5 alkoxy group or hydroxyl group, and the resulting compound of formula (II) is transformed, in a reaction medium with pH above 7, into the compound of formula (I) or b) the compound of formula (III) is reacted with an anhydride of general formula (V) and the resulting compound of formula (II) transformed, in a reaction medium with pH above 7, into the compound of formula (I), or c) a compound of formula (II) is transformed, in a reaction medium with pH above 7, into the compound of formula (I), and if desired, the resulting compounds of formula (I), before or after isolation, are transformed into acid addidon salts, or the compounds of formula (I) are liberated from their acid addition salts. Thus a process for the preparation of intermediates useful in synthesis of angiotensin II antagonists is disclosed.
Patent CA-2298547-A1 (CA)
Title: Methods and apparatus for determining instantaneous elastic recoil and assistance pressure during ventilatory support
Inventor: BERTHON-JONES MICHAEL
IPC: A61M16/00
Filed: 1997-09-23
Abstract: The apparatus provides for the determination of the instantaneous phase in the respiratory cycle, subject's average respiration rate and the provision of ventilatory assistance. A microprocessor receives an airflow signal from a pressure transducer coupled to a port at a mask.    The microprocessor controls a servo that in turn controls the fan motor and thus the pressure of air delivered by the blower. The blower is coupled to a subject's mask by a conduit. The invention seeks to address the following goals: while the subject is awake and making substantial efforts the delivered assistance should be closely matched in phase with the subject's efforts; the machine should automatically adjust the degree of assistance to maintain at least a specified minimum ventilation without relying on the integrity of the subject's chemoreflexes; and it should continue to work correctly in the presence of large leaks.
Patent CA-2301599-A1 (CA)
Title: Substituted 4-oxo-napthyridine-3-carboxamides as gaba brain receptor ligands
Inventor: ALBAUGH PAMELA
IPC: A61P25/20
Filed: 1998-08-24
Abstract: The present invention encompasses structures of Formula (I) or the pharmaceutically acceptable non-toxic salts thereof wherein: X is hydrogen, halogen, (un)substituted alkyl, (un)substituted alkoxy or amino; and Y is (un)substituted alkyl, aryl, or heteroaryl, which compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors. These compounds are useful in the diagnosis and treatment of anxiety, Down Syndrome, sleep, cognitive and seizure disorders, and overdose with benzodiazepine drugs and for enhancement of alertness.