baber/WOPTO huggingface dataset:
Patent DO-P2006000133-A (DO)
Title: Derivados de 4,5 diarilpiroxol, su preparación y su aplicación en terapeútica
Inventor: CONGY CHRISTIAN
Filed: 2006-06-12
Abstract: La presente invención tiene como objeto los compuestos de la formula (I): en la que: X representa un grupo - R1 representa un atomo de hidrógeno o un grupo alquilo(C1-C4); R2 representa: alquilo (C1-C12); un radical carbociclico no aromatico (C3-C12) no sustituido o sustituido; metilo sustituido con un radical carbociclico no aromatico (C3-C12) no sustituido o sustituido; un radical fenilo, bencilo o bencidrilo no sustituidos o sustituidos; un radical heterociclico no sustituido o sustituido; metilo sustituido con un radical carbociclico no aromatico (C3-C12) no sustituido o sustituido; - R3 representa alquilo(C1-C5) o cicloalquilo(C3-C7); - R4 representa fenilo no sustituido o sustituido; - R5 representa fenilo no sustituido o sustituido; Proceso de preparacion y aplicacion en terapeutica.
Patent DO-P2010000187-A (DO)
Title: Derivados de oxadiazol activos en 1-fosfato de esfingosina
Inventor: HEER JAG PAUL
IPC: C07D413/14
Filed: 2010-06-18
Abstract: LA PRESENTE SOLICITUD DESCRIBE COMPUESTOS A BASE DE OXADIAZOL DE FORMULA (I) ACTIVOS EN 1-FOSFATO DE ESFINGOSINA (S1P) EN PARTICULAR UTILES PARA TRATAR LUPUS ERITEMATOSO; A ES FENILO O UN ANILLO DE HETEROARILO DE 5 O 6 ESLABONES; B SE SELECCIONA DE UNO DE LOS SIGUIENTES: FORMULAS: (A) (B) (C).
Patent DO-P2019000251-A (DO)
Title: Procedimiento de fabricación de productos alimenticios porosos secos
Inventor: TIMOTHY D DURANCE
IPC: A23L3/54
Filed: 2019-10-02
Abstract: Un procedimiento de fabricación de un tentempié deshidratado, poroso y crujiente, de hortaliza, de carne o de marisco. Se congela una porción de hortaliza, tal como patata, batata, zanahoria, remolacha o chirivía, o una porción de carne o de marisco, formándose cristales de hielo en la porción de alimento. La porción congelada es expuesta a una radiación de microondas en un deshidratador de microondas a una presión de vacío en la cual el punto de ebullición del agua está por encima de 0 ºC, causando que la porción congelada se descongele y que el agua se evapore de la porción descongelada. La evaporación deja poros que fueron formados por los cristales de hielo en la porción de alimento, dando como resultado un tentempié deshidratado, poroso y crujiente.
Patent DO-P2023000161-A (DO)
Title: Compuesto de quinazolina para inducir la degradación de la proteína kras mutante g12d
Inventor: TOMOHIRO YOSHINARI
IPC: A61K31/517
Filed: 2023-08-15
Abstract: [Problema] Proporcionar un compuesto útil como ingrediente activo de una composición farmacéutica para tratar el cáncer de páncreas. [Medio de resolución] Los presentes inventores han estudiado un compuesto que es útil como ingrediente activo de una composición farmacéutica para tratar el cáncer de páncreas y han descubierto que un compuesto de quinazolina tiene una excelente acción inductora de degradación sobre una proteína KRAS mutante G12D y una actividad inhibidora de KRAS mutante G12D, y puede usarse como agente terapéutico para el cáncer de páncreas, con lo cual se completa la presente invención. El compuesto de quinazolina o una sal de este de la presente invención se puede usar como agente terapéutico para el cáncer de páncreas.
Patent EC-SP12012188-A (EC)
Title: Cajón
Inventor: ORGELDINGER WOLFGANG
IPC: B65D85/34
Filed: 2012-09-28
Abstract: Un cajón comprende un fondo y dos paredes laterales y paredes extremas opuestas, en pares, respectivas, donde el fondo está curvado con forma de arco hacia el interior del cajón, de modo que se proporciona un espacio (S) entre una superficie inferior del fondo y un plano (P) definido por un extremo inferior del cajón.
Patent EE-200400069-A (EE)
Inventor: GABOR PAL S
IPC: A61P9/12
Filed: 2003-03-13
Abstract: The invention relates to the use of citalopram or a pharmaceutically acceptable salt thereof for the preparation of pharmaceutical compositions suitable for the treatment of elevated (high) blood pressure, normalization of blood pressure or the decrease of elevated blood pressure and/or prevention of elevated blood pressure.
Patent EG-23374-A (EG)
Title: Chewing gum in powder and a method of preparation.
Inventor: SOZZI GIUSEPPE
IPC: A23G4/00
Filed: 2003-04-02
Granted: 2005-02-28
Abstract: The subject of the invention is a novel chewing gum in tablet form which can be produced by direct compression of a gum formulation in powder form; the chewing gum thus obtained is characterized by a pleasant chewability which remains unchanged throughout the chewing period and is substantially identical to that of conventional chewing gums. The chewing gum in powder form is produced by a method which comprises the following steps:  a) mixing of a soft basic gum with at least one sweetener and, optionally, at least one other typical chewing-gum ingredient, at a temperature of between 35 and 75 DEG C, b) cooling of the mixture thus obtained to a temperature of between 0 and -40 DEG C and preferably between -10 and -40 DEG C, c) grinding and subsequent screening of the mixture thus obtained to a particle size of less than 10 mesh, d) optional mixing of the powder thus obtained with at least one anti-agglutination agent, e) optional compression of the mixture thus obtained.
Patent GB-189702232-A (GB)
Title: Improvements in Apparatus for Operating Switches on Tramways and Railways.
Inventor: HAKEN EDUARD VON
Filed: 1897-01-27
Granted: 1897-03-06
Abstract: 2232. Haken, E. von, and Waldeck, M. Jan. 27. Points and switches, railway and tramway, operating from vehicle. A three-armed lever pivoted. between the rails has cam surfaces i, i<1> on two of its arms adapted to be moved by one or other of two rods d, d' supported on the vehicle by springs. The third arm has pins e embracing the tongue.
Patent GB-189705609-A (GB)
Title: Improvements in or applicable to Pocket or Folding Knives, or other Folding Instruments.
Inventor: CLARKSON JOSEPH
Filed: 1897-03-03
Granted: 1897-06-05
Abstract: 5609. Clarkson, J. March 3. Handles; combination tools.-The tool a is so engaged by the spring c that it cannot be closed unless the spring is left free to turn about a central pivot by turning aside a bearing-block d at the other end of the spring. This block may serve as a screwdriver, or be variously devised.
Patent GB-189705692-A (GB)
Title: Improvements in Sanitary and other Pipes.
Inventor: WAKEFIELD ARTHUR
Filed: 1897-03-03
Granted: 1897-11-13
Abstract: 5692. Wakefield, A. March 3. Spigot-and-socket joints.-In order to secure a true invert in sanitary pipes, the lower part of the socket is corrugated internally as shown at D, the ridges forming a solid bed on which the spigot rests. A groove J extends transversely of the corrugations, and the socket has holes K, L, and M for introducing cement. The spigot may be corrugated instead of the socket if desired.
Patent GB-189707614-A (GB)
Title: Improvements in Street Fire Alarms and the like.
Inventor: SHAW WILLIAM ALBERT
Filed: 1897-03-24
Granted: 1898-02-12
Abstract: 7614. Shaw, W. A., and Shaw, E. A. March 24. Telegraph and telephone calls.-Pillars or boxes for street fire or police alarms are provided with a door a' having a glass or other breakable panel b, behind which a pullhandle c is located. The effect of pulling the handle c is to raise the latch d by the inclined plane c<1> and at the same time to send a signal to the central office. The latch d may be raised independently of the handle c. The box contains an indicator l for showing a call from the central station and a set of telephone apparatus.
Patent GB-189714029-A (GB)
Title: An Improved Safety-lock, chiefly designed for the Doors of Railway Trucks, Vans, and the like.
Inventor: STEFAN COLOMAN
Filed: 1897-06-08
Granted: 1897-08-07
Abstract: 14,029. Stefßn, C. June 8. Locks, key.-A lock for railway trucks, vans, and the like is arranged to destroy a controlling-mark when the lock is opened. The lock catch G is pivoted at v and locked in the fastening position by a lug k, on a spring-returned bolt F, engaging in a recess in the boss of the catch. The bolt F is operated through a lever E by one arm of a follower A which is turned by a key J, Fig. 4. The follower, together with a disc O, Fig. 2, is pivoted on a key pin, and a nose i on the key disengages a locking- spring z from the disc 0 when the key is turned. The second arm of the follower operates a spring- returned lever D through the lever B, the free end of the lever D carrying a spring catch d, which, when the lock is unlocked, engages with a lever f connected to the bolt F and guided in a slot u in the case. The lever D operates a holder S, containing the mark, through a pin r, the holder sliding on the outside of the lock case. When the bolt F has been retracted, the catch G can be turned upwards until the inclined surface l comes opposite the lug k, allowing the bolt to shoot back slightly, the lever f then engaging the catch d and holding the holder in a position accessible for the insertion of a new mark, the original one having been destroyed during opening by a knife blade L on the disc O. The parts shown in Fig. 2 are covered by a plate with a protected sight hole opposite the mark, a door t, connected with the holder, opening or closing the lower portion as the lock is operated.
Patent GB-189716240-A (GB)
Title: Process and Apparatus for the Construction of Seamless Connecting Sockets for Tubes.
Inventor: BERTHOLD RICHARD
Filed: 1897-07-08
Granted: 1897-09-04
Abstract: 16,240. Berthold, R., and Lowenstein, S. July 8. Stamping. - Consists of means for stamping seamless angle-pieces, specially applicable to the joints of cycle frames, from a flat sheet of metal. A circular blank is stamped into the shape of a cylinder with a closed hemispherical end. It is then placed in a support M<4>, and a hole is punched in it at one side near its end by a tool S<4>, after which it is placed on a support M<5> and stamped into the shape shown at 6 by a die S<5>. It is then placed in a box G, G' so that the hole i points towards one end of the channel g, while the shank lies in the channel g<1>. There the hole i is opened out by suitable tools, a second hole is made opposite it, and it is finally made to assume the shape shown at 11. Other forms may be made.
Patent GB-189717249-A (GB)
Title: Improvements in or relating to Drums for Germinating and Drying Malt.
Inventor: RAETZELL HERMANN
Filed: 1897-07-21
Granted: 1897-09-11
Abstract: 17,249. Raetzell, H. July 21. Drying malt.- The Figures show a drum used for drying and germinating malt. It consists of an interior drum 10, made of perforated plates connected by thumb - screws 11 to radial partitions 5 and d secured to a closed outer drum 1. The inner drum is not a complete cylinder, but in one part consists of inclined plates b, c resting on one or more prolonged partitions d. Air enters at A and passes through the hole 14 in the hollow pin 13, through one of the holes 12 into the hood 7, thence through the opening 4 into the space 15 between the end pieces 2, 8, and thence through one of the openings 9, after which it passes into the inner drum through the perforations and out again as shown by the arrows in Fig. 1. The positions of the openings 14 can be adjusted by the handles 16, thereby varying the direction of the air current to suit requirements. When the drum is at rest, the malt is equally distributed in the two troughs formed by the plates c, b. When the drum rotates, the whole of the malt is lifted to one side, and then slowly dropped, so that no solid core can be produced. The interior of the apparatus is accessible by means of manholes 3.
Patent GB-189717819-A (GB)
Title: Improvements connected with Street or Outside Gas Lamps, and in the Arrangement of Unprotected Incandescent Mantles therein.
Inventor: SHELDRAKE JOHN HOLMES
Filed: 1897-07-29
Granted: 1898-05-07
Abstract: 17,819. Sheldrake, J. H. July 29. Incandescent gas lamps.-Relates to lamps for street and outdoor use generally. In the upper part of the lantern is placed an inverted reflector, from the centre of which rises a tube C. The products escape through this tube, downdraughts b e i n g prevented by cones E. The gas pipe F is carried well up into the lantern, and has an enlargement G in which are provided air inlets. The upper end of the mantle is within the tube C or is near thereto. A cone J, which may be transparent, directs air against the exterior of the mantle. A burner, carrying the reflector and other fittings described above, may be screwed into the place of the nipple in any ordinary street or outside lantern.
Patent GB-189722122-A (GB)
Title: Improvements in Brakes for Rubber Tired Wheels.
Inventor: SPIKINS WILLIAM BENJAMIN
Filed: 1897-09-27
Granted: 1898-01-22
Abstract: 22,122. Spikins, W. B., and Mayes, A. H. Sept. 27. Brakes. - Fig. 2 shows a form suitable for a bicycle. A forked bearing c, preferably attached to the sleeve e, supports a centre pin a by means of the adjusting-screws d. The pin a is provided with a central boss a', and the rollers b, b, which come into contact with the sides of the tyre, and are preferably faced with rubber or other suitable material. The brake rod f passes through the sleeve e, and is terminated at its lower end by a collar f<2> and a brake shoe f<1>, which is adapted to bear upon the central boss a<1>. The sleeve e is supported by a bracket provided with an eye g<1>, which is attached to the fork crown. Or the bracket may be dispensed with and replaced by arms pivoted to the fork crown. The brake is operated in the usual manner by means of the handle-bar lever.
Patent GB-189728332-A (GB)
Title: Improvements in Apparatus for Testing Drains and other Pipes.
Inventor: THWAITE BENJAMIN HOWARTH
Filed: 1897-12-01
Granted: 1898-11-26
Abstract: 28,332. Thwaite, B. H., and Allen, H. Dec. 1. Testing pipes and pipe joints. - Calcium carbide mixed with some gelatinous or saccharine substance is sealed up in glass tubes or pressed into bales, tablets, &c., for introduction to the pipe to be tested. The acetylene gas given off upon contact with water reveals any leak which may exist, or the accumulated pressure may be used to test the strength of the pipe &c.
Patent GB-189728617-A (GB)
Title: A New or Improved Sash Fastener.
Inventor: FRY WILLIAM
Filed: 1897-12-03
Granted: 1898-01-08
Abstract: 28,617. Fry, W. Dec. 3. Sash fastenings. -The bar A of the fastener is locked by a catch C pivoted on it and engaging the quadrant plate B. The knob e is on the catch, and the latter is turned against a stop a on the bar to enable the bar to be turned back.
Patent GB-189730600-A (GB)
Title: Improvements in Toys.
Inventor: GEDNEY MEAVE THOMSON
Filed: 1897-12-28
Granted: 1898-02-19
Abstract: 30,600. Gedney, M. T. Dec. 28. Mechanical toys.-A toy is caused to move upon wheels in an upright position for a short distance, but soon falls forwards and runs in that position a further distance. In the form shown, there are two supporting-wheels a, a', and an actuating- wheel a<2> operated by an elastic band B secured at b and wound upon the shaft a<3> by means of an external crank. The toy then moves forward, but in consequence of the portion in front of the shaft a<3> being slightly heavier than that behind, it falls to the position shown in Fig. 4. The head is pivoted at d, and is provided with an extension carrying a weight d<1>, whereby the head is raised away from the ground. When the toy has the form of an animal, such as a dog, the tail is also provided with an extension and a weight. The figure shown has a bellows E provided with a reed F which is sounded by the toy falling down, the bellows striking the ground.
Patent GB-189802300-A (GB)
Title: Improvements in Apparatus for Automatically Stopping Railway Trains in Motion.
Inventor: GRAMONT HONORE
Filed: 1898-01-28
Granted: 1898-12-17
Abstract: 2300. Gramont, H. Jan. 28. Brakes. - Relates to means for automatically stopping railway trains when a signal is at ' danger,' or, otherwise, when and where necessary. A. branch pipe e from the ordinary airbrake pipes is fitted at its outer end with a glass tube g, which is closed at its free end. A bar m is pivoted near the line and connected to the ordinary signal - operating mechanism, so that, when the signal is at ' danger,' the bar is in position, as shown, to break the tube g and so apply the brakes. Supports or carriers for removable bars, such as m, are arranged at intervals along the permanent way, so that a bar can be mounted, independently of the signals, to stop a train when necessary. The pipe e can be closed by the cock h when the glass g is broken.
Patent GB-189809500-A (GB)
Title: Improved Adjustable Pipe Wrench.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1898-04-25
Granted: 1899-01-07
Abstract: 9500. Thompson, W. P., [England, J. E., and Bousfield, C. J.]. April 25. Hooks.-The bent upper jaw 4 of the wrench shown may be turned down upon its pivot and used as a hook for lifting articles.
Patent GB-189809660-A (GB)
Title: Improvements in Air-tight Covers for the Cleaning or Inspection Eyes of Soil Pipes, Drains, Traps, or Sewers.
Inventor: BUCHAN DAVID WADDELL
Filed: 1898-04-27
Granted: 1898-07-09
Abstract: 9660. Buchan, D. W. April 27. Inspection openings, covers for. A socket A, permanently fixed in the faucet of the pipe, is made with an annular groove A<1> in which dips a flange B' on a cover B held down by a bayonet-joint engagement with the socket A. A second cover C is held in position either by a pin C' engaging with a projection B<3>, or by a screw. In one modification, the covers B and C are made in one ; in another, a third cover is used.
Patent GB-189819535-A (GB)
Title: Improvements in and connected with Electric Motors partly applicable to Dynamos.
Inventor: MAQUAY SAMUEL WILLIAM
Filed: 1898-09-14
Granted: 1899-08-12
Abstract: 19,535. Maquay, S. W., and Vanderpump, P. E. Sept. 14. Motors, gearing for; armatures. - The armature a of an electric motor is mounted on a sleeve b running on the central spindle e, to which it transmits motion through speed reducing or increasing gear c, j<1>, j, i. The gear-wheels are enclosed in a casing k, on opening which they can be changed to alter the power. Between the sleeve and the spindle are arranged ball bearings, each consisting of two tapering rings d and f, one of which is adjusta b I e longitudinally to take up wear, the races being of greater width than the balls to permit of this. Brush-holders; terminals, arrangement of; motors, controlling.-The carbon brushes n are carried by arms r on a ring divided into two insulated parts, and they are pressed upon the commutator p by springs q. Current is supplied to them through rings u and v, with which spring plugs t on the arms r make contact. By means of a toothed segment y<4> and pinion y<3> actuated by a lever y, the brushes can be moved over the commutator so as to vary the speed of the motor. The movement of the brush gear may be utilized to reverse the current through the motor, either by a suitable disposition of contacts or by a switch actuated by a pin o<1>. When the motor is run from a primary battery, the lever y may operate means for raising the zincs out of the liquid or for separating the electrodes in the cells.
Patent GB-189821139-A (GB)
Title: Improvements in Brakes for Wheel Carriages.
Inventor: PRICE ROBERT
Filed: 1898-10-07
Granted: 1899-07-01
Abstract: 21,139. Price, R. Oct. 7. Brakes.-Relates to brakes of the type described in Specification No. 19,594, A.D. 1896. The slotted plate e, fixed to the forked end c<2> of the brake lever c by the pin f, has hooks e<2> to which the springs g are connected, the other ends of the springs being passed over the hooks a' in the plate a, which is pivoted on the pin b. When the lever c is actuated, the plate a turns on the pin b so that one of the ends yields until the whole of the brake-block surface is applied to the tyre. In a modification, the brake plate is pivoted to the erd of the brake lever, the slotted plate being fixed to this end by a screw pin.
Patent GB-189903327-A (GB)
Title: An Improved Frame or Sliver-can.
Inventor: COOPER WILLIAM
Filed: 1899-02-14
Granted: 1900-02-10
Abstract: 3327. Cooper, W. Feb. 14. Metal, sheet, seaming and joining; soldering.-In the manufacture of sliver cans for use in spinning mills &c., the edges of the body and bottom are closed down on one another, and then further secured by being dipped in molten metal or solder ; and after the binder or hoop C has been applied to the can, it is again dipped into melted solder above the depth of the bottom ring D, so as to sweat or solder the binder C, bottom B, and body A of the can together.
Patent GB-189915951-A (GB)
Title: Improvements in Seltzogenes or Apparatus for Aerating Liquids.
Inventor: DURAFORT VICTOR ERNEST JULES
Filed: 1899-08-04
Granted: 1900-06-23
Abstract: 15,951. Durafort, V. E. J. Aug. 4 Storing u n d e r pressure. - Relates to seltzogenes of the kind described in Specification No. 2 4 6 4, A.D. 1898, and consists of means for closing the mouth of the gas discharge conduit of the container, capsule, or cartridge for the compressed carbonic acid. A hollow piece b is fitted tightly in the opening at the upper part of the container a. The inner diameter of the upper part of the piece b is larger than that of the lower part. In the upper part is screwed a stopper f, in which is a central longitudinal passage h. In the lower part is an opening k for the escape of carbonic acid, and above this opening is a piston-like piece d, the diameter of which is slightly smaller than that of the lower part of the piece b, so that it can easily slide in the said part, and allow a free passage for the gas between the lower inner wall of the piece b. The upper side of the piece d is covered with a flexible washer e. The pressure of the gas in the container a forces the -piece d up against the lower end of the stopper f, and, when it is desired to cause gas to escape from the container a, slight and abrupt blows are given to the piece d by means of a rod introduced into the passage h.
Patent GB-189921724-A (GB)
Title: Improvements in Separators or a Combined Air Trunk and Expansion Chamber, with Improvements in the Form and Construction thereof.
Inventor: ROSE JOHN
Filed: 1899-10-31
Granted: 1900-04-07
Abstract: 21,724. Rose, J. Oct. 31. Sifting and separating grain.-The grain is fed from the hopper g to the air-trunk a, the lighter grain being carried upwards and conveyed through the semicircular passage a<1> to the expansion chamber b. An automatic discharge valve c is provided for the light grain. The expansion chamber opens at d into side trunks e, which communicate with the fan f. The grain which tails over from the sieve j is again aspirated at k.
Patent GB-189923302-A (GB)
Title: Apparatus for Emptying the Contents of Casks or Barrels containing Plastic Materials.
Inventor: SMULDERS FRANZ
Filed: 1899-11-22
Granted: 1900-05-12
Abstract: 23,302. Smulders, F. Nov. 22. Contents, (solid), removing. - S o l i d or plastic materials, such as fats, margarine, &c., are removed from casks by apparatus such as that shown in F i g s. 1 and 6. The cask l to be emptied is placed, mouth downwards, over the crosshead e of a piston-rod c, which is caused to ascend by fluid pressure operating on the piston b. A lower rod c depending from the piston slides within gearing by which it is rotated. To the crosshead are pivoted at k, Fig. 6, cutters f having rolls g at the ends, and smaller cutters are secured at the centre of the crosshead. Thus, as the rotating crosshead ascends, layers of the fat &c. will be cut off and fall on to a shoot, which is heated. When the crosshead reaches the top of the cask, a tappet o on the lower rod c trips an arm p to cut off the fluid from the piston b.
Patent GB-190009493-A (GB)
Title: An Improved Food Product or Article of Food
Inventor: TRITTON ARTHUR FREDERICK
Filed: 1900-05-24
Granted: 1901-03-30
Abstract: 9493. Tritton, A. F., and Beyer, L. F. E. May 24. Food preparations.-A food is produced by steeping cereals or leguminous substances in an aqueous solution of either potash, lime, phosphoric acid, or soda, and when the liquid is absorbed heating the product by steam, either in closed or open vessels, and finally drying and grinding. The product may be eaten in this state, or may be baked or boiled &c.