baber/WOPTO huggingface dataset:
Patent DE-69433663-D1 (DE)
Inventor: TINDALL J
IPC: C07K14/47
Filed: 1994-06-29
Granted: 2004-05-06
Abstract: The present invention provides an isolated preparation of monoclonal or polyclonal antibodies which react specifically with human prostate-specific glandular kallikrein (hK2), but which do not cross-react with human prostate-specific antigen (PSA), as well as immunogenic hK2 antigens useful to provide such antibodies.
Patent DE-69435328-D1 (DE)
Inventor: OLEFSKY JERROLD
IPC: A61K31/425
Filed: 1994-09-14
Granted: 2011-01-13
Abstract: Treatment of impaired glucose tolerance, in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus comprises admin. of :(a)eg. a cpd. of formulae (I) or (II)(or a salt of these);(b) a cpd. of formula (IV) (or a cationic salt of (IV), or an acid addn. salt of (IV) when it contains a basic N atom);(c) a cpd. of formula (V) (or a cationic salt of (V), or an acid addn. salt of (V) when A or B is N);or (d) eg. a cpd. of formulae (VII) (or a tautomer, salt or solvate): R1, R2 = H or 1-5C alkyl; R3 = H, 1-6C aliphatic acyl,etc.;R4, R5 = H, 1-5C alkyl or 1-5C alkoxy; or R4+R5 = 1-4C alkylenedioxy; m = 1- 3; W = CH2 or CO etc.;Y, Z = O or NH; R11 = opt. substd. alkyl, alkoxy,etc.;L1, L2 = H or lower alkyl; or L1+L2 = alkylene;V = CH=CH, N=CH, CH=N or S; Za = H, 1-7C alkyl, 3-7C cycloalkyl,etc.;Z1 = H or 1-3C alkyl;q = 1- 3; A, B = CH or N, provided that they are not both N; X1 = S, O, SO2,etc.; s = 0-1; Y1 = CHR20 or R21; Z2 = CHR22, CH2CH2, CH=CH,etc.;R1y is not given; X2, X3 = H, Me, CF3, phenyl,etc. A2 = alkyl, opt. substd. aryl or opt. substd. aralkyl; A3 = a benzene ring with \~3 opt. substits.;R24 = H, alkyl, acyl, or opt. substd. aryl or aralkyl; or A2+R24 = 2-3C polymethylene (opt. substd. by alkyl or aryl, adjacent substits. together with the methylene carbon atoms opt. forming an opt. substd. phenylene gp.); R25, R26 = H; or R25+R26 = a bond; X4 = O or S; n = 2-6.
Patent DE-69500492-D1 (DE)
Inventor: DE MERINGO ALAIN
IPC: C03C13/00
Filed: 1995-05-24
Granted: 1997-09-04
Abstract: A biologically degradable glass-fiber composition characterized by the following constituents in percent by weight:SiO<sub>2</sub>45 to 60Al<sub>2</sub>O<sub>3</sub>less than 2CaO + MgO10 to 16Na<sub>2</sub>O + K<sub>2</sub>Omore than 18 to 23B<sub>2</sub>O<sub>3</sub>10 to 18P<sub>2</sub>O<sub>5</sub>0 to 4BaO0 to 1Diverse0 to 2.
Patent DE-69510561-D1 (DE)
Inventor: BOWDEN MARTIN
IPC: C07C67/54
Filed: 1995-11-02
Granted: 1999-08-05
Abstract: PCT No. PCT/GB95/02570 Sec. 371 Date Jan. 31, 1997 Sec. 102(e) Date Jan. 31, 1997 PCT Filed Nov. 2, 1995 PCT Pub. No. WO96/16018 PCT Pub. Date May 30, 1996The invention provides an improved process for the preparation of a lower alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid in which the corresponding lower alkyl ester of a carboxylic acid selected from 6-bromo-6-chloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid and 6,6-dichloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid is treated with an alkali metal lower alkoxylate in the presence of an aromatic hydrocarbon solvent under conditions under which the lower alcohol of the alkoxylate is removed from the reaction mixture by distillation with the aromatic solvent. The products are useful as intermediates in the manufacture of pyrethroid insecticides.
Patent DE-69510825-D1 (DE)
Inventor: DELLA VALLE FRANCESCO
IPC: A61K9/06
Filed: 1995-03-17
Granted: 1999-08-19
Abstract: PCT No. PCT/EP95/01002 Sec. 371 Date Sep. 23, 1996 Sec. 102(e) Date Sep. 23, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25509 PCT Pub. Date Sep. 28, 1995The use of N-acyl derivatives of aminoalcohols with mono- and di-carboxylic acids for the prevention and treatment of diseases connected with hyper and prolonged excitation by excitatory amino acids is described.
Patent DE-69514860-D1 (DE)
Inventor: PIANEZZOLA SERGIO
IPC: H02B1/052
Filed: 1995-04-21
Granted: 2000-03-09
Abstract: A modular electric apparatus with a rail hook-up device (2,3), comprising a slider (2) of a plastics material housed slidably in a seat (10) of the apparatus located on the back thereof and provided with a metal rail hook-up tooth (11), the hook-up tooth being provided with a metal (or doubled wire) tab (3) for sliding movement and protection against wear, bent into a straddler and overlapping the tooth (11), the tab (3) also playing the roles of a bias spring with the slider in the hooked position and of a stop element which ensures a stable open position for the hook-up device to facilitate removal of the apparatus from the rail. <IMAGE>
Patent DE-69521037-D1 (DE)
Inventor: LEONARDI AMEDEO
IPC: C07D401/04
Filed: 1995-03-17
Granted: 2001-06-28
Abstract: PCT No. PCT/EP95/01001 Sec. 371 Date Sep. 17, 1996 Sec. 102(e) Date Sep. 17, 1996 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25726 PCT Pub. Date Sep. 28, 1995New qunazolinyl-amino derivatives useful as  alpha 1-adrenoreceptor blockers are described. These compounds can be used as therapeutic agents for treating afflictions and diseases related to hyperactivity of the  alpha -adrenergic system, such as, for example, arterial hypertension, prostate benign hyperplasia, high intraocular pressure and hpercholesterolemia. Processes for the preparation of the above said compounds are also described.
Patent DE-69523812-D1 (DE)
Inventor: RENWICK CRAIG W
IPC: B29C45/27
Filed: 1995-05-08
Granted: 2001-12-20
Abstract: An injection molding melt distribution manifold (10) and method of making it with a melt passage (12) extending from a single inlet (14) to a plurality of outlets (18). The melt passage (12) has a branching portion (26) formed by machining matching grooves (54,56) in opposing surfaces (48,50) of two steel plates (42,44) and then integrally brazing them together. The manifold has an embedded electrical heating element (30) received in a channel formed by two other matching grooves (70,72) in the opposing surfaces of the two plates. The channel is then integrally filled with nickel by heating under a partial vacuum. The electrical heating element (30) which extends around and is in or near the same plane as the branching portion (26) of the melt passage (12) to ensure rheological and thermal balance of the melt flowing therethrough.
Patent DE-69527401-D1 (DE)
Inventor: VAN GESTEL JACOBUS
IPC: H04N21/43
Filed: 1995-03-14
Granted: 2002-08-22
Abstract: During recording of an MPEG information signal on a record carrier (40), transport packets (Pk) are stored in signal blocks in a track (1) on the record carrier (40). x transport packets of the MPEG information signal are stored in the second block sections (SB) of y signal blocks, where x and y are integers, x≥1 and y>1, more specifically, y>x. Further, third block sections (TB) are present in one or more of the second block sections in the y signal blocks of a group for storing additional information, which additional information relates to the specific application of recording and reproducing the MPEG information signal on/from the record carrier. <IMAGE>
Patent DE-69527847-D1 (DE)
Inventor: CHARNOCK-JONES STEPHEN
IPC: A61K31/57
Filed: 1995-05-26
Granted: 2002-09-26
Abstract: PCT No. PCT/GB95/01212 Sec. 371 Date May 9, 1997 Sec. 102(e) Date May 9, 1997 PCT Filed May 26, 1995 PCT Pub. No. WO96/32708 PCT Pub. Date Dec. 7, 1995Disclosed are: a composition for use in the treatment of endometriosis, comprising an agent capable of interfering with the production and/or activity of VEGF, and a physiologically acceptable carrier substance; a composition for the treatment of endometriosis comprising an agent which inhibits the activation and/or recruitment of peritoneal macrophages, and a physiologically acceptable carrier; and method of making the compositions and their use in the treatment of endometriosis.
Patent DE-69527955-D1 (DE)
Inventor: ENGSTAD ROLF
IPC: A23K1/16
Filed: 1995-04-18
Granted: 2002-10-02
Abstract: β-(1-6)-Glucanese treatment of glucan from yeast cells, pure or feed grade, especially yeast from the family Saccharomyces and particularly Saccharomyces cerevisiae, provides a novel glucan product suitable for use in enhancing the stimulation of host animal immune systems. Solubilization of such yeast cell glucan is further disclosed to extend the usefulness of yeast cell glucan as an adjuvant.
Patent DE-69530098-D1 (DE)
Inventor: MARTINSEN ORJAN G
IPC: A61B5/05
Filed: 1995-10-09
Granted: 2003-04-30
Abstract: PCT No. PCT/NO95/00184 Sec. 371 Date Apr. 10, 1997 Sec. 102(e) Date Apr. 10, 1997 PCT Filed Oct. 9, 1995 PCT Pub. No. WO96/10951 PCT Pub. Date Apr. 18, 1996In order to measure the moisture content in skin, especially in the keratinous layer (stratum corneum), at least two electrodes are employed, at least one of which electrodes is placed on the skin where moisture has to be measured, the electrodes are supplied with a periodic voltage with a frequency of less than 50 kHz, and the susceptance in the keratinous layer is measured beneath the electrode or electrodes. In an apparatus for measuring the moisture content in skin three electrodes are employed, a periodic voltage being applied to two of these. The susceptance is measured below one of the electrodes, uninfluenced by the other electrodes, the measurement thus being truly monopolar.
Patent DE-69533793-D1 (DE)
Inventor: POWELL LLEWELLYN
IPC: A23L5/20
Filed: 1995-03-15
Granted: 2004-12-30
Abstract: A process for extracting a compound or composition of matter from a raw material containing that compound or composition as a constituent part is disclosed. The process comprises the steps of (1) contacting a sample of the raw material with an extraction solvent comprising 1,1,1,2-tetrafluoroethane and a co-solvent selected from an alkane and a hydrocarbon ether, (2) forming a solvent liquor comprising the extraction solvent and an extract from the raw material, and (3) separating the solvent liquor containing the extract from the raw material.
Patent DE-69602083-D1 (DE)
Inventor: HAIRY PATRICK
IPC: B22D17/32
Filed: 1996-01-25
Granted: 1999-05-20
Abstract: PCT No. PCT/FR96/00126 Sec. 371 Date Jul. 25, 1997 Sec. 102(e) Date Jul. 25, 1997 PCT Filed Jan. 25, 1996 PCT Pub. No. WO96/22852 PCT Pub. Date Aug. 1, 1996An installation has a fixed die portion and a moving die portion, ejector rods under the control of an actuator fed with control fluid, and a spray device for spraying a coating substance. A monitoring apparatus comprises a pressure sensor for continuously measuring the pressure of a control fluid, a device for measuring and recording the pressure as a function of time, a device for comparing the recorded measurement with a reference measurement, and a device for modifying the spraying of the coating substance as a function of the comparison.
Patent DE-69603721-D1 (DE)
Inventor: KHAN RIAZ
IPC: A61P31/04
Filed: 1996-05-08
Granted: 1999-09-16
Abstract: Succinic acid hemiester of hyaluronic acid or its partial or total esters, having repeating unit of formula (I), and their salts with heavy metal X, are new. In (I), R1-R3 = H or CO(CH2)2COOY; Y = a negative charge or H; R = OH, O or alcoholic residue; and X has valency between 1 and 6. Also claimed is prepn. of heavy metal salts of (I) comprising: (a) converting hyaluronic acid Na salt into a pyridinium, tetraalkylammonium, tetraalkylphosphonium, tetraarylammonium, or tetraarylphosphonium salt in presence of water and aprotic solvent; (b) treating with succinic anhydride in presence of organic base as catalyst; (c) removing cation by dialysis, providing free (I); (d) opt. freeze-drying to recover solid (I); (e) treating either soln. or solid (I) with aq. soln. of heavy metal salt; and (f) recovering by filtration and vacuum drying.
Patent DE-69604629-D1 (DE)
Inventor: DE JONG MAXIMUS JOHANNA FRANCI
IPC: F16H55/02
Filed: 1996-07-30
Granted: 1999-11-18
Abstract: The invention relates to a divisible sprocket wheel manufactured from synthetic material and having a gear ring (1b) and a hub portion (1a), comprising two wheel halves (1) which are manufactured by means of injection molding and have their axial faces (1f) abutting against each other, and means (3, 4) for enabling fixing the wheel halves together, wherein each wheel half (1) is solid and consists of a first synthetic material forming at least one half of the hub portion of the sprocket wheel; a second synthetic material forming at least one half of the gear ring of the sprocket wheel and the two radial outer faces (1d, 1e) of the wheel half, and a third synthetic material forming the internal portion (1e) of the body of the wheel half. Through the features according to the invention, a sprocket wheel having good transport properties is obtained which is cheap to manufacture and extremely simple to keep clean. <IMAGE>
Patent DE-69608545-D1 (DE)
Inventor: WEATHERUP JAMES
IPC: A01C23/00
Filed: 1996-02-13
Granted: 2000-06-29
Abstract: The disclosure relates to an apparatus for discharging slurry/liquid into the ground in which inclined discs (40) create channels in the ground, slurry is deposited in these channels through injection nozzles (42) and the loose earth disturbed by the inclined discs is restored to close the channels by further inclined rotary discs (54). Slurry is evenly distributed to each injection nozzle by a rotary distribution valve (61). Operating pressure required by the discs to penetrate the ground is controlled by compression springs (50). Ground engagement depth is controlled by wheels (43).
Patent DE-69610416-D1 (DE)
Inventor: GRAY F
IPC: A61F5/44
Filed: 1996-03-25
Granted: 2000-10-26
Abstract: A disposable absorbent article that effectively prevents the leakage of body fluids beyond its confines. The article of the present invention comprises a body having a fluid-impermeable backsheet, an intermediate, fluid-absorbing core, and a fluid-permeable topsheet. A pair of leg cuff assemblies is attached to the body. Each assembly comprises a cuff standing portion and a cuff base portion. The assemblies are composed of two hydrophobic nonwoven layers. A first layer is composed of a spunbonded web and a second layer is composed of a meltblown fiber. The first layer extends from the free, unattached end of the cuff standing portion to the distal edge of the article defining the leg opening. The second layer is provided where needed and in weights as needed to provide maximum assembly hydrophobicity with a minimum use of material. This construction allows the cuff assemblies to form fluid-impermeable dams which prevent passage of body fluid beyond the article along its leg hole sides.
Patent DE-69613705-D1 (DE)
Inventor: SHUE HO-JANE
IPC: A61K31/445
Filed: 1996-08-29
Granted: 2001-08-09
Abstract: The invention relates to compounds of formula (I) wherein Z, Rc, y, m, u, Ar2, n, X, Rc',(I) and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
Patent DE-69614184-D1 (DE)
Inventor: HELAINE CHRISTIAN
IPC: A01J25/15
Filed: 1996-05-13
Granted: 2001-09-06
Abstract: The method for eliminating by pressing the whey contained in curd (3) located in a micro-perforated cheese mould (2) consists of placing the cheese mould in a sealed enclosure (1). Two pressing cycles are made, each comprising a first phase in which a pressure is exerted on the curd contained in the mould, and a depression created in the enclosure. In the second phase the pressure exerted on the curd is ended and a pressure created in the enclosure equal to atmospheric pressure. Each pressing cycle has a duration of about 30 minutes and can be repeated up to ten times according to the nature of the whey. During the second phase the high pressure in the enclosure is less than or equal to 10<4> Pa during the second phase
Patent DE-69623799-D1 (DE)
Inventor: SCHEEL-KRUEGER JOERGEN
IPC: A61P43/00
Filed: 1996-11-04
Granted: 2002-10-24
Abstract: PCT No. PCT/EP96/04793 Sec. 371 Date Jun. 4, 1998 Sec. 102(e) Date Jun. 4, 1998 PCT Filed Nov. 4, 1996 PCT Pub. No. WO97/16451 PCT Pub. Date May 9, 1997The present invention discloses compounds of the formula, or any of its enantiomers or any mixture thereof, a pharmaceutically acceptable addition salt thereof or the N-oxide thereof wherein X and Y together forms =O, =S, =NOR2, =CR3R4, =N-CN, =N-NR7R8, -(CH2)m-, or -W'-(CH2)p-W''-, or one of X and Y is hydrogen and the other is -OR5, -SR5, or -NR5R6 Z is hydrogen, -COOR9; R3 and R4 are independently hydrogen, halogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, aryl, arylalkyl, or -(CH2)q-COOR2; R2, R5 and R6 are independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, aryl, or arylalkyl, -CO-alkyl, or -SO2-alkyl; R7 and R8 are independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, aryl, or arylalkyl; R9 is alkyl, alkenyl or alkynyl; R1 is alkyl, alkenyl, alkynyl, aryl, or arylalkyl; where said aryl groups may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino and nitro; W' and W'' are each independently O or S; n is 1, 2, 3, or 4; m is 2, 3, 4, or 5; p is 1, 2, 3, 4, or 5; and q is 0, 1, 2, 3,or 4. The compounds possess valuable properties as monoamine neurotransmitter, i.e dopamine, and serotonine, reuptake inhibitors.
Patent DE-69626275-D1 (DE)
Inventor: DAVIES M
IPC: B29B15/10
Filed: 1996-03-11
Granted: 2003-03-27
Abstract: A method for producing flexible, low-bulk towpreg which involves powder coating a bundle of unspread fiber tows (35) arranged in a predetermined cross-sectional shape, and the resulting towpreg. During the powder coating process, the resin powder particles (82) do not enter into the fiber bundle, but rather only coat the surface fibers comprising the tows, resulting in dry fibers (80) in the core of the towpreg and outer fibers which are coated with a discontinuous sheath of resin on the surface of the towpreg surrounding the core of dry fibers. The resin layer on the surface of the towpreg is formed by a partial melting of the powder particles. A post treatment process can be used to convert flat ribbon towpreg produced in accordance with the present invention into flexible unidirectional tape.
Patent DE-69627064-D1 (DE)
Inventor: HUBER BERND
IPC: D06M13/224
Filed: 1996-01-29
Granted: 2003-05-08
Abstract: A method of treating a surface of a fibre, e.g. cellulosic fibre, with a finish in which the surface finish is applied as an aqueous emulsion stabilised at a first pH value and at the latest when applied to the fibre the emulsion is caused to destabilise by a change in the first pH value. The invention also relates to cellulosic fibre and threads thereof and to tampons made from cellulosic fibre.
Patent DE-69636893-D1 (DE)
Inventor: MICALI SILVIO DR
IPC: G06Q20/02
Filed: 1996-11-01
Granted: 2007-03-22
Abstract: A method and system for overcoming the problems associated with certificate revocation lists (CRL's), for example, in a public key infrastructure. The invention uses a tree-based scheme to replace the CRL.
Patent DE-69704973-D1 (DE)
Inventor: VISCA MARIO
IPC: C09K3/30
Filed: 1997-03-05
Granted: 2001-07-05
Abstract: Extinguishing compositions comprising a liquid extinguishing agent constituted by hydrofluoropolyethers having general formula HF2CO(CF2O)n(CF2CF2O)mCF2H wherein n and m are integers comprised between 0 and 20, excluding when m and m are contemporaneously 0 and having boiling point between 30 DEG  and 200 DEG C and having an O/C molar ratio between 0.5-1.
Patent DE-69706542-D1 (DE)
Inventor: HEIKKILAE HEIKKI
IPC: C07C31/18
Filed: 1997-06-23
Granted: 2001-10-11
Abstract: The invention relates to a method for producing xylitol. According to the method, a mixture that contains xylose or xylonic acid or that is concentrated with respect to xylonic acid is reduced, and xylitol is recovered.
Patent DE-69707928-D1 (DE)
Inventor: ST GEORGE M
IPC: C07C229/24
Filed: 1997-11-17
Granted: 2001-12-06
Abstract: A process is disclosed for isolating the disodium salt of racemic and meso isomers of ethylenediamine-N,N'-disuccinic acid from alkaline aqueous solutions.
Patent DE-69715395-D1 (DE)
Inventor: MIYAMOTO MISAO
IPC: A61K31/66
Filed: 1997-03-17
Granted: 2002-10-17
Abstract: An amorphous solid dispersion of efonidipine hydrochloride having a high intestinal absorbability can be formed by subjecting a mixture containing efonidipine hydrochloride of the formula (I), hydroxypropylmethylcellulose acetate succinate and optionally a thermostabilizer to a step A of heat treatment at from 85 to 140° C. or mechanochemical treatment at from 0 to 140° C., and then to a step B of dipping treatment into a water-containing solution, impregnation treatment with a water-containing solution or contacting treatment with a water vapor-containing gas; or treating the above-mentioned mixture with a hot steam at from 100 to 140° C. and a high pressure. Further, in the above-mentioned step A, the mixture is subjected to high frequency heating, making it possible to give a solid dispersion of efonidipine hydrochloride having a high intestinal absorbability without using the step B. This process is quite advantageous in the production in that the use of an organic solvent is not required. Formula (I):
Patent DE-69722993-D1 (DE)
Inventor: CLINE JOHN B
IPC: A61F5/445
Filed: 1997-04-10
Granted: 2003-07-31
Abstract: Measurements of the topography of the stomal area of the patient are taken manually, by photographs taken at different angles, computerized touch probing, magnetic resonance imaging, computerized axial tomography, laser scanning or by casting. Information relating to the measurements is recorded on a card, a template or electronically. The recorded information is digitized and stored in a database, along with information concerning patent history and preferences. The electronic information is utilized to select the physical attributes of the wafer and pouch which best suit the needs of the user. The appropriate tools are automatically selected, adjusted and guided to fabricate customized wafers and pouches by computerized fabrication equipment. Parameters which can be varied include the size, shape and location of the stoma receiving opening, the wafer outline and surface contour, the adhesive type, the pouch size and shape, the tail location, the tap type and location, the flange style and the filter location, as well as the accessories which are required. <IMAGE>
Patent DE-69725272-D1 (DE)
Inventor: JOSEF MICHAEL J
IPC: D03D13/00
Filed: 1997-07-09
Granted: 2003-11-06
Abstract: A papermakers fabric (10) for forming, press and dryer sections of a papermaking machine comprises a system of interwoven machine-direction (MD) yarns (12, 14) forming pairs of a first and second (MD) yarns woven as single yarns and of different cross section shape one being rectangular and cross- machine (CD) yarns (16).
Patent DE-69726059-D1 (DE)
Inventor: SAVOUREY GUSTAVE
IPC: A61B5/0205
Filed: 1997-07-10
Granted: 2003-12-18
Abstract: The portable module is intended for recording the cardiac activity of a person with the aid of a device providing an ECG signal. It includes a main energy source (A) connected to a secondary energy source (18) which supplies a temperature sensor (4) via a control circuit. The module further includes a data collection and processing unit (3) receiving the ECG signal which includes a filtering stage (5). This is connected to two integrators (7,8) having different time constants. The outputs of the integrators are connected to a comparator (11) providing a signal (E3) representative of the cardiac cycles. A further circuit then records the duration (T) of the cardiac cycles, with a view to determination of the instantaneous cardiac frequency. The temperature at which the measurement is made is also detected and recorded.