baber/WOPTO huggingface dataset:
Patent WO-2021134045-A1 (WO)
Title: Procédés et compositions d'inhibition de dihydroorotate déshydrogénease en combinaison avec un agent thérapeutique anti-cd38
Inventor: BYRD JOHN C
IPC: C07D215/12
Filed: 2020-12-26
Abstract: La présente invention concerne des combinaisons et des procédés pharmaceutiques de traitement d'un état clinique, par exemple, l'AML, par l'administration à un sujet d'une combinaison pharmaceutique comprenant un inhibiteur DHODH et un agent thérapeutique anti-CD38 tel qu'un anticorps anti-CD38. La combinaison pharmaceutique peut en outre comprendre un ou plusieurs agents thérapeutiques additionnels. Cet abrégé concerne un outil de balayage aux fins de recherche dans ce domaine technique et ne vise pas à être limitant de la présente invention.
Patent WO-2021067990-A1 (WO)
Inventor: FINKELSTEIN EMIL
IPC: A61M5/32
Filed: 2020-09-29
Abstract: A drug delivery device may include a housing having an opening and a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening. A biasing member may initially be retained in an energized state, and may be released to drive a plunger to expel a drug from the drug storage container. The plunger may be configured to selectively rotate from an initial rotational position to a second rotational position under a biasing force exerted by the biasing member, and translate linearly in a distal direction to drive the stopper through the drug storage container after rotating from the initial rotational position to the second rotational position. A releaser member may have an initial position wherein the releaser member retains the biasing member in the energized state, and a second position wherein the releaser member generates an audible end-of-dose signal.
Patent WO-2021142139-A1 (WO)
Title: Reel system and method
Inventor: MATARI NADER N
IPC: B65H75/24
Filed: 2021-01-07
Abstract: A reel system that includes a drum that receives a coil of flexible pipe. A first flange that removably couples to a first side of the drum. A second flange that removably couples to a second side of the drum. The first flange and the second flange secure the coil of flexible pipe to the drum.
Patent WO-2021150614-A1 (WO)
Title: Compounds and methods for selective c-terminal labeling
Inventor: HUANG HAIDONG
IPC: C07K1/107
Filed: 2021-01-20
Abstract: The present disclosure relates to compounds and methods for selective C-terminal functionalization of peptides. In certain embodiments, the compounds have improved water-solubility, and are suitable for use in connection with peptide sequencing methodologies.
Patent WO-2021158721-A1 (WO)
Title: Bicycle belt or chain tensioner and internally geared hub conversion kit
Inventor: STACY RODRIGUEZ PERRIN
IPC: B62M11/14
Filed: 2021-02-04
Abstract: Bicycle belt or chain drive tensioning systems and IGH-thru-axle conversion systems are described that includes first and second anti-rotation keys, a bushing, and first and second fasteners configured to center the IGH laterally within first and second dropouts of the bicycle. The belt or chain tensioning device includes a mounting clamp, a swing arm assembly with a stepped pivot shaft, a swing arm, a first pulley rotatably supported by the pivoted shaft, and a second pulley rotatably attached to the swing arm, the first pulley, and the swing arm rotating about a longitudinal axis of the stepped pivot shaft. Methods for assembly and operation of such systems are also disclosed.
Patent WO-2021178161-A1 (WO)
Inventor: NIELSEN BO
IPC: H02J4/00
Filed: 2021-02-23
Abstract: A power distribution system is provided for an aircraft on the ground, comprising a first electrical load, operably coupled to the aircraft on the ground and configured to receive at least a first portion of a predetermined maximum input power provided by a power supply; at least one second electrical load, electrically coupleable to the aircraft on the ground and configured to receive at least a second portion of said predetermined maximum input power provided by said power supply, and a controller, adapted to monitor at least one parameter of the power consumed by any one of said first electrical load and said at least one second electrical load, and control the power consumption of at least said first electrical load so that the total power consumption of said first electrical load and said at least one second electrical load does not exceed said predetermined maximum input power; wherein said predetermined maximum input power is provided via a single power line between said power supply and an input port of said first electrical load.
Patent WO-2021178257-A1 (WO)
Inventor: FRIETZE KATHRYN
IPC: A61P25/04
Filed: 2021-02-28
Abstract: The present invention is directed to virus-like particles (VLPs) preferably derived from Qbeta bacteriophage which are engineered to conjugate to derivatives of opioid drugs. The opioid drugs are conjugated at high density to the virus-like particles to achieve long- lasting and high titer antibodies to the drugs of interest. Methods of treatment are also described.
Patent WO-2021174203-A1 (WO)
Inventor: NICHOLAS DAVID
IPC: C02F5/00
Filed: 2021-03-01
Abstract: The present disclosure provides an improved scale inhibiting formulation that is effective, environmentally friendly, and does not add any organic compounds or traditional polymeric compounds to treated water. The scale inhibiting composition includes molecular clusters of polyammonium bisulfate (PABS), which can interact physically, chemically, or physio-chemically with one or more ions in the water or water-containing system being treated. That interaction inhibits scale accretion and/or removes previously formed scale.
Patent WO-2021183489-A1 (WO)
Title: High precision syringe with removable pump unit
Inventor: LEE CHAO
IPC: A61M5/31
Filed: 2021-03-09
Abstract: A digital syringe is used with conventional polymer disposable syringe construction to be practical in the medical environment. Errors associated with the larger volumes of the syringes (which exacerbate minor errors in plunger position) and the flexibility and dimensional variations of the polymer plungers are accommodated by direct measurement of the syringe plunger position rather than indirect measurement of motor position and inference of syringe plunger position. This direct measurement eliminates mechanical tolerances ("stack up") in the motor, gear train, and lead screw on plunger movement, an effect exacerbated by flexibility of the plunger and changes in syringe resistance and medicament viscosity, for example, with different medicaments or when the syringe is refrigerated. The digital syringe may be combined with the motor unit to provide additional versatility.
Patent WO-2021183559-A1 (WO)
Title: A spinning top centrifuge
Inventor: MEADOWS VICKI
IPC: B04B9/10
Filed: 2021-03-09
Abstract: This invention concerns a centrifugal device that houses adapters for commercial or scientific samples (or tubes containing such samples) and is manually operated. In preferred embodiments, the adapter is housed in a modern version of a spinning top that is powered by repetitive pumping motion using a helical rod and clutch mechanism.
Patent WO-2021221803-A1 (WO)
Title: Corner segment having protrusions on wear zones
Inventor: CONGDON THOMAS M
IPC: E02F3/815
Filed: 2021-03-15
Abstract: In one aspect, a corner segment (102), configured to be mounted to a work implement (100), may include a body (104) having a plurality of surfaces including a rear surface (148), an upper surface (116), a front surface (118), a bottom surface (136), an outer side surface (122), an inner side surface (150), and a corner surface (120) that is adjacent to each of the front surface, the outer side surface, the upper surface, and the bottom surface. A portion of the bottom surface forms a bottom surface wear zone (160, 162), and a portion of the front surface forms a front surface wear zone (154), The corner segment may also include a plurality of protrusions (154) provided on wear zones, the wear zones including the bottom surface wear zone and the front surface wear zone.
Patent WO-2021195419-A1 (WO)
Inventor: BUGENHAGEN MICHAEL
IPC: H04L29/06
Filed: 2021-03-25
Abstract: Novel tools and techniques in a telecommunication network are provided for implementing a data link layer control plane that may comply with the Ethernet standard and with sub-millisecond transmission control capabilities across multiple dis-similar technologies and bandwidth links. The data link protocol system may be implemented through a cloud system. Setting and resource registries of the nodes in the network may be displayed at a cloud portal for users to adjust the network. The change in the setting may be communicated through an application programming interface of a compute host to change the setting of the network. Each DLP node includes a slow agent and a fast agent. The slow agent is configured to transmit data messages through Ethernet frames. The fast agent is configured to transmit control messages through DLP frames. Each DLP frame includes a header only without a payload and the header carries a control message.
Patent WO-2021202309-A1 (WO)
Title: Method of making coextruded crosslinked polyolefin foam with polyamide cap layers
Inventor: SIERADZKI PAWEL
IPC: B29C44/24
Filed: 2021-03-26
Abstract: Described herein are physically crosslinked, closed cell continuous multilayer foam structures that includes a foam layer comprising polypropylene, polyethylene, or a combination of polypropylene and polyethylene and a polyamide cap layer. The multilayer foam structure can be obtained by coextruding a multilayer structure comprising at least one foam composition layer and at least one cap composition layer, irradiating the coextruded structure with ionizing radiation, and continuously foaming the irradiated structure.
Patent WO-2021207028-A1 (WO)
Inventor: BAUER RALPH
IPC: B01D67/00
Filed: 2021-04-02
Abstract: Un support poreux pour des membranes d'épaisseur d'ordre nanométrique d'une rugosité de surface locale inférieure à 100 nanomètres, approprié pour le support de membranes à couche unique d'environ 1 à 500 nanomètres d'épaisseur, et pour des membranes à couches multiples allant jusqu'à environ 2 000 nanomètres dans une épaisseur agrégée. Le support présente également une taille de pore de surface inférieure à 100 nanomètres et une porosité de surface inférieure à 50 pour cent.
Patent WO-2021252069-A1 (WO)
Title: Bipolar junction transistor optical modulator
Inventor: RAM RAJEEV J
IPC: H01S5/00
Filed: 2021-04-12
Abstract: Semiconductor optical modulators are described that utilize bipolar junction transistor (BIT) structure within the optical modulator. The junctions within the BIT can be designed and biased to increase modulator efficiency and speed. An optical mode may be located in a selected region of the BIT structure to improve modulation efficiency. The BIT structure can be included in optical waveguides of interferometers and resonators to form optical modulators.
Patent WO-2021226379-A1 (WO)
Title: Low-cost, ipd and laminate based antenna array module
Inventor: GORBACHOV OLEKSANDR
IPC: H01L27/02
Filed: 2021-05-06
Abstract: An antenna array module includes two or more antenna elements arranged in an array, each of the two or more antenna elements formed as a respective integrated passive device (IPD), and a multi-layer printed circuit board (PCB) including one or more metal layers forming one or more feed lines of the antenna elements. The antenna array module may include a radio frequency (RF) front end integrated circuit disposed on an opposite side of the multi-layer PCB from the two or more antenna elements. One or more signal output pins of the RF front end integrated circuit may be connected to the one or more feed lines. The antenna array module may include conductive contacts external to the multi-layer PCB for routing input signals through the multi-layer PCB to one or more signal input pins of the RF front end integrated circuit.
Patent WO-2021236967-A1 (WO)
Inventor: FAKOORIAN SEYED ALI AKBAR
IPC: H04W56/00
Filed: 2021-05-20
Abstract: L'invention concerne un procédé de communications sans fil par un équipement utilisateur de liaison latérale, récepteur, consistant à détecter un signal optique de synchronisation de liaison latérale (SL-SS) émis par un UE de liaison latérale, émetteur. Le SL-SS optique peut comporter un motif avec un nombre réduit de symboles de canal de diffusion de liaison latérale physique (PSBCH). Le procédé consiste également à transmettre une demande requérant des SL-SS supplémentaires, à partir de l'UE de liaison latérale de transmission sur des ressources indiquées. Un autre procédé consiste à recevoir une demande de signaux supplémentaires de synchronisation de liaison latérale (SL-SS) à partir d'un UE de liaison latérale, récepteur. Ce procédé consiste en outre à transmettre des SL-SS supplémentaires en réponse à la demande.
Patent WO-2021247498-A1 (WO)
Title: Système de traitement de déformation osseuse, dispositif et procédés associés
Inventor: BOFFELI TROY J
IPC: A61B17/56
Filed: 2021-06-01
Abstract: L'invention concerne des dispositifs de correction de déformation osseuse et des procédés d'utilisation de tels dispositifs pour corriger des déformations osseuses. Le dispositif peut comprendre un corps allongé, un bras de manipulation réglable couplé de façon mobile au corps allongé, le bras de manipulation réglable étant conçu pour se déplacer axialement et latéralement, et un guide de coupe pouvant être fixé de manière amovible au corps allongé de dispositif.
Patent WO-2021252391-A1 (WO)
Title: Methods and vectors for enhancing expression and/or inhibiting degradation of protein
Inventor: WANG TING-FANG
IPC: C07K14/47
Filed: 2021-06-07
Abstract: The present disclosure provides a method for increasing expression and/or inhibiting degradation of an interested polypeptide in a host cell with the steps of constructing an expression vector comprising a polynucleotide coding an intrinsically disordered region (IDR) with high S/T and/or Q content and a polypeptide coding the interested polypeptide, transforming the expression vector to a host cell and culturing the host cell under conditions that allow for expression of the interested polypeptide.
Patent WO-2021262670-A1 (WO)
Inventor: BIVANS MATTHEW
IPC: A61B5/08
Filed: 2021-06-22
Abstract: The invention provides an IV system for monitoring a patient that is positioned on the patient's body. The IV system includes: 1) a catheter that inserts into the patient's venous system; 2) a pressure sensor connected to the catheter that measures physiological signals indicating a pressure in the patient's venous system; 3) a motion sensor that measures motion signals; and 4) a processing system that: i) receives the physiological signals from the pressure sensor; ii) receives the motion signals from the motion sensor; iii) processes the motion signals by comparing them to a pre-determined threshold value to determine when the patient has a relatively low degree of motion; and iv) process the physiological signals to determine a physiological parameter when the processing system determines that the motion signals are below the pre-determined threshold value.
Patent WO-2021263026-A1 (WO)
Inventor: ABBADESSA GIOVANNI
IPC: C07K16/28
Filed: 2021-06-24
Abstract: Disclosed herein are methods for treating a cancer in a subject in need thereof, comprising administering IL-2 conjugates in combination with an anti-EGFR antibody.
Patent WO-2022015739-A1 (WO)
Title: Virus filtered/sterilized airflows directed to passengers in vehicle
Inventor: MESKIMEN SAMUEL COLT
IPC: B64D13/06
Filed: 2021-07-13
Abstract: Directed virus filtered and/or sterilized airflows are provided to individual passenger seats creating virus filtered/sterilized air regions at passenger seats. The directed filtered/sterilized airflows protect passengers from viruses and other contaminates exhaled by passengers seated in adjacent seats and enable greater recycling of cabin air and associated decreased use of outside air pressurized for cabin use and associated decreased flight fuel consumption. A directed airflow assembly includes a virus filter/sterilization chamber with a virus filter and/or sterilization device configured to receive return cabin air through an input duct, to filter and/or sterilize viruses in the return cabin air, and to provide the virus filtered/sterilized air through an output duct. The air return ducts extend from air return vents in a seat surface of each of a plurality of passenger seats to the chamber. The air supply ducts extend from the chamber to air supply vents directing virus filtered/sterilized air toward the passenger seats.
Patent WO-2022031412-A1 (WO)
Title: Techniques for efficient network security for a web server using anomaly detection
Inventor: JOHNSTON JOSHUA MICHAEL
IPC: G06F21/55
Filed: 2021-07-14
Abstract: A method described herein involves various operations directed toward network security. The operations include accessing transaction data describing network traffic associated with a web server during an interval. Based on a count of new transactions involving an online entity during the interval according to the transaction data, a short-term trend is determined for the online entity. The operations further include applying exponential smoothing to a history of transactions of the online entity to compute a long-term trend for the online entity. Based on a comparison between the short-term trend and the long-term trend for the online entity, an anomaly is detected with respect to the online entity in the network traffic associated with the web server. Responsive to detecting the anomaly, an access control is implemented between the online entity and the web server.
Patent WO-2022026367-A1 (WO)
Inventor: SHIFFMAN ROTEM
IPC: G06F3/0481
Filed: 2021-07-26
Abstract: The present disclosure describes a software-based solution for rendering digital crowds in real-time. The system at large is a network of machines that processes and ingests broadcast camera feeds and tracking data and then leverages an augmented reality system for compositing and tracking platforms to render tens of thousands of crowd members on top of live footage.
Patent WO-2022026479-A1 (WO)
Inventor: BAZOBERRY CARLOS
IPC: A62B7/04
Filed: 2021-07-27
Abstract: A system (10) and method for conserving oxygen and other gases supplied to a recipient. A supply conduit (408) supplies gas from a source (406) to a reservoir (404), which retains a volume of gas at ambient pressure. A conduit (422) supplies gas from the reservoir (404) to the recipient. An inflation detection system, such as an electro-mechanical system or a contactless system (456), detects when the reservoir (404) is below a state of inflation and when the reservoir (404) is inflated to the state of inflation. A valve system prevents gas from flowing from the source (406) and into the reservoir (404) when the reservoir (404) is at the predetermined state of inflation, and the valve system permits gas to flow from the source (406) into the reservoir (404) when the reservoir (404) is below the predetermined state of inflation whereby gas within the reservoir (404) can be continually replenished without pressurization above ambient pressure.
Patent WO-2022032030-A1 (WO)
Title: Loss circulation treatment fluid injection into wells
Inventor: AL-MALKI BANDER S
IPC: E21B43/10
Filed: 2021-08-05
Abstract: A protective tubular is run downhole into a wellbore in a subterranean formation. A non-metallic tubular is disposed within the protective tubular. The non-metallic tubular includes an adapter. The adapter includes a spring-loaded latch, a ball seat, a shear pin, and a ball catcher. While intact, the shear pin holds a position of the non-metallic tubular relative to the protective tubular. A ball is used to shear the shear pin of the adapter, thereby allowing the non-metallic tubular to move relative to the protective tubular. Pressure is applied to the ball to move the non-metallic tubular relative to the protective tubular. The non-metallic tubular is coupled to the protective tubular using the spring-loaded latch of the adapter. Pressure is applied to the ball to shear the ball seat of the adapter. A fluid is flowed into the non-metallic tubular through an opening defined by the adapter.
Patent WO-2022046844-A1 (WO)
Title: Dihydroquinazolin-2-one derivatives as selective cytotoxic agents useful in the treatment of hiv
Inventor: CONVERSO ANTONELLA
IPC: C07D403/06
Filed: 2021-08-25
Abstract: The present disclosure is directed to tetrahydroquinazoline derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV naïve cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).
Patent WO-2022060772-A1 (WO)
Title: Environmentally friendly refrigerant compositions
Inventor: COUCHOT DAVID
IPC: C09K5/04
Filed: 2021-09-15
Abstract: A refrigerant composition includes R125 (pentafluoroethane), R134a (1,1,1,2- tetrafluoroethane), R600a (isobutane) and a polyol ester (POE) lubricant. In one exemplary embodiment, the refrigerant includes about 53-57 wt% R125, about 40-44 wt% R134a, about 1- 5 wt% R600a and no more than about 1 wt% POE. In another embodiment, the refrigerant composition includes about 54-56% R125, about 41-43 wt% R134a, about 2-4% R600a and about 0.3-0.7 wt% POE. In yet another embodiment, the refrigerant composition includes about 54.63 wt% R125, about 41.72 wt% R134a, about 2.98 wt% R600a and about 0.67 wt% POE. Manufacturing the refrigerant composition includes charging a vessel with about 53-57 wt% R125, about 44 wt% R134a, about 1-5 wt% R600a to form as 100 wt% charge, and then injecting no more than about 1 wt% POE.
Patent WO-2022072265-A1 (WO)
Title: Systems and methods for account management
Inventor: SEBURN TED
IPC: G06Q50/28
Filed: 2021-09-27
Abstract: The disclosure relates to a method of implementing account management and product distribution techniques. An example method includes providing a supply management platform in communication with a supplier computer system, a distributor computer system, and a retail computer system; receiving a sales objective from the supplier computer system or the distributor computer system, the sales objective being derived using a predictive model in the supplier computer system, the sales objective being approved using the distributor computer system; providing the sales objective to the retail computer system; receiving a status update related to the sales objective; forwarding the status update to at least one of the supplier computer system or the distributor computer system; and based on the status update, facilitating an adjustment of a supply of at least one of the products for the at least one of the retail accounts.
Patent WO-2022086994-A1 (WO)
Title: Automated customer review matching
Inventor: HOFFMAN DAVID
IPC: G06Q30/00
Filed: 2021-10-19
Abstract: The subject disclosure encompasses solutions for matching customer information with customer reviews. A process of the disclosed technology includes steps for aggregating customer data associated with a customer, retrieving a plurality of customer reviews, wherein each of the customer reviews describe customer satisfaction with a service provided by a corresponding service provider, extracting review metadata for each of the plurality of customer reviews, and matching the customer with at least one of the customer reviews based on the customer data and the extracted review metadata. Systems and machine-readable media are also provided.
Patent WO-2022093609-A1 (WO)
Inventor: ROGGOW TIMOTHY A
IPC: C05D9/02
Filed: 2021-10-21
Abstract: A foam control agent and method of controlling foam for agricultural products by use of a foam control agent, wherein the agent comprises at least a branched alcohol.
Patent WO-2022094124-A1 (WO)
Title: Systèmes et procédés de séparation de co2
Inventor: FUGLEVAND WILLIAM A
IPC: F25J3/00
Filed: 2021-10-28
Abstract: Systèmes et procédés de séparation de CO2