baber/WOPTO huggingface dataset:
Patent EP-0458829-B1 (EP)
Inventor: SMITH LARRY J
IPC: C12N15/09
Filed: 1990-01-24
Granted: 1996-09-25
Abstract: The present invention provides methods useful in autologous bone marrow transplantation and cancer therapy. According to one aspect of the invention, bone marrow cells from a patient having cancer are treated with selected antisense oligonucleotides in order to deplete the bone marrow of malignant cells prior to infusion back into the bone marrow donor. In a separate embodiment, selected antisense oligonucleotides are administered systemically for anticancer therapy.
Patent EP-0457824-B1 (EP)
Inventor: DALE JAMES LANGHAM
IPC: C12Q1/6813
Filed: 1990-02-13
Granted: 1999-06-23
Abstract: A method for detecting a specific polynucleotide sequence in a material is disclosed. The method includes exposing said material to an oligonucleotide primer having a sequence complementary to part of said specific polynucleotide sequence wherein said primer binds to part of said polynucleotide sequence when present in said material. Primer bound to the polynucleotide sequence is extended wherein any extended primer includes a detectable element and/or a separation element. Any extended primer is then separated into a fraction wherein said fraction does not have detectable element not included in said extended primer. One then determines whether any extended primer is present in said fraction by assaying said fraction for said extended primer wherein the presence of said extended primer is indicative of the presence of the specific polynucleotide sequence in said material and the absence of said extended primer in said fraction is indicative of the absence of the specific polynucleotide sequence in said material.
Patent EP-0414886-B1 (EP)
Title: Method and apparatus for making electrophotographic prints of photographic negatives
IPC: G03G13/20
Filed: 1990-03-14
Granted: 1993-09-08
Abstract: A selected finish is applied to an electrophotographic print of a photographic negative at a fusing station (90). One of a plurality of finishing rollers (92, 92a, 92b, 92c) is moved into operative engagement with a fusing roller (95) to provide the desired finish.
Patent EP-0422164-B1 (EP)
Title: Immunogene multivalent de grande taille
Inventor: MESCHER MATTHEW F
IPC: A61K31/675
Filed: 1990-03-19
Granted: 1994-11-30
Abstract: L'invention concerne l'immunisation et/ou l'introduction thérapeutique in vivo de ligands liés seuls ou en combinaison avec d'autres molécules, disposés sur des supports solides et ayant un diamètre supérieure à 0,2 ν environ pour provoquer et augmenter les réponses par l'entremise des cellules T in vivo.
Patent EP-0469014-B1 (EP)
Inventor: ULRICH ARMANDO
IPC: B01F23/00
Filed: 1990-04-20
Granted: 1994-08-17
Abstract: Emulgator-free liquid emulsion and method and device for producing the emulsion. The emulsion consists of at least one hydrophobic liquid phase and at least one hydrophilic liquid phase, one of said phases being a disperse phase of the emulsion, which has a stable colloidal state with a particle size of the disperse phase of 1,000 nm or less, preferably a particle size in the range of 100 to 500 nm. In the method for producing the liquid emulsion in absence of an emulgator, the liquid phases are repeatedly recirculated in the form of their mixture through a mixing chamber which has an axially symmetrical shape and in which the mixture is brought into a rotational flow about the axis with a flow component parallel to the axis and in which the flow pressure of the mixture is reduced in flow direction by gradually increasing the flow velocity of the mixture up to the coaxial discharge of the rotating mixture from the mixing chamber to a minimum pressure being near to the vapor pressure of the mixture without reaching or falling below the vapor pressure. In the device the mixing apparatus (1) comprising a mixing chamber of a rotational symmetrical shape in a hollow element (14) with a plurality of tangential inlet openings (15) opening into a first chamber portion connected to a second chamber portion having a tapering section in flow direction and an axial outlet being coaxial with the axis of the mixing chamber, the first chamber portion has a rotational paraboloid form and the second chamber portion has a rotational inverse hyperboloid form, said axial outlet being a cylindrical duct portion (18), the parabolic wall (14) of said first chamber portion defining a focal line falling in the axis of rotation, said inlet openings (15) being arranged at a wide cross-section of the first chamber portion which is connected to the second chamber portion at the widest cross-section thereof, and the sum of the cross-sections of the inlet openings (15) substantially corresponds to the cross-section of said duct portion (18).
Patent EP-0474690-B1 (EP)
Inventor: KERRY JOHN THE GROVE
IPC: G02B6/44
Filed: 1990-06-01
Granted: 1994-04-20
Abstract: A splice organiser comprises a tray having a plurality of formers (14, 15) which control the minimum bend radius of the fibres, a groove for retaining a splice, an enclosure into which coiled fibre loops are introduced and permitted to expand so that they are retained by the resilience of the fibre itself, and a plurality of guide tracks (23, 24, 25) which enable fibres to enter and exit the organiser at any corner of the tray.
Patent EP-0477277-B1 (EP)
Inventor: HEINSOHN HENRY G
IPC: C12N9/00
Filed: 1990-06-13
Granted: 1995-04-19
Abstract: L'invention concerne un procédé pour récupérer et purifier de la chymosine lors d'une fermentation pour la production microbienne de chymosine. Le mélange de fermentation est filtré de manière à réaliser un filtrat contenant ladite chymosine. On prépare d'abord ledit filtrat en l'ajustant à un pH faible, environ 2, et/ou en ajustant la concentration de sel dans ledit filtrat à au moins environ 2M. Le mélange aqueux du filtrat est mis en contact avec une résine phényle-sépharose, qui lie sélectivement ladite chymosine provenant du filtrat. Le filtrat qui reste après le contact avec ladite résine phényle-sépharose est rejeté, la colonne de résine phényle-sépharose étant éluée avec de l'eau ou avec une solution de sel dilué de manière à obtenir de la chymosine essentiellement pure lors d'une seule étape d'élution.
Patent EP-0452426-B1 (EP)
IPC: E03C1/10
Filed: 1990-07-20
Granted: 1992-12-02
Abstract: Les dispositifs antiretour qui sont destinés en particulier à être montés sur des conduites d'eau potable possèdent un carter de circulation (1) comportant une conduite d'amenée et une conduite de sortie (2 et 3) et à l'intérieur duquel sont disposés un clapet d'amenée à ressort (4) et un clapet de sortie à ressort (8) ainsi qu'une chambre centrale (13) disposée entre les deux clapets (4, 8). Lorsque la différence de pression entre cette chambre et la conduite d'amenée (2) devient inférieure à une valeur minimum déterminée, la chambre peut être reliée à l'atmosphère extérieure grâce à l'ouverture d'un clapet de décharge dont le corps (28) est relié, dans ce but, à un élément de commande (18, 18') pouvant être exposé d'un côté à la pression d'amenée et de l'autre à la pression dans la chambre centrale et pouvant aussi être relevé au-dessus de son siège (30) en libérant à la fois une ouverture pour l'écoulement de l'eau et une ouverture d'aération conduisant à la chambre centrale (13). Pour simplifier encore la construction de ce clapet de décharge tout en améliorant les possibilités d'écoulement de l'eau et d'aération de la chambre centrale (13), l'ouverture d'écoulement de l'eau du clapet de décharge et l'ouverture d'aération sont intégrées à une ouverture de liaison unique (14, 32) de section relativement importante disposée entre la chambre centrale (13) et l'atmosphère extérieure et qui est dégagée progressivement par le corps (28) du clapet en fonction de la course d'ouverture de celui-ci.
Patent EP-0489807-B1 (EP)
Inventor: FAULKNER DAVID WYNFORD
IPC: G02B6/28
Filed: 1990-08-14
Granted: 1995-11-02
Abstract: PCT No. PCT/GB90/01282 Sec. 371 Date Feb. 28, 1992 Sec. 102(e) Date Feb. 28, 1992 PCT Filed Aug. 14, 1990 PCT Pub. No. WO91/03753 PCT Pub. Date Mar. 21, 1991.A reflective star coupler for a distributed switch optical network for narrow band and broad band broadcast communication incudes on port terminated in a reflective surface or device, a signal amplifier and/or filter is disposed in the path between the port and the reflective device to reintroduce the light from that port into the coupler in an amplifier state or selectively according to wavelength. The amplifying device may be a semiconductor laser having a reflective coating on one face thereof.
Patent EP-0449339-B1 (EP)
Inventor: TSE SAMUEL W
IPC: B29C48/09
Filed: 1986-05-07
Granted: 1999-07-14
Abstract: A packaging film (10) is characterized by the inclusion of a layer (14) of a vinylidene chloride copolymer, e.g. VDC-methylacrylate copolymer, between at least two other layers (16, 18) which contain ethylene vinyl acetate, and optionally linear low density polyethylene. The film may be unoriented or molecularly oriented, may be heat set, and if oriented, optionally the film may be cross-linked. A process of making the cross-linked film includes the steps of joining the layers in face-to-face contact e.g. by coextrusion and of crosslinking the film after assembly of the vinylidene chloride copolymer layer into the structure. Cross-linking can be achieved by electron beam irradiation at a level of at least 1.5 megarads. The film can have a further layer or layers e.g. for heat sealing and for improving its abuse resistance, and can be made into a heat shrinkable bag suitable for packaging foodstuffs.
Patent EP-0477675-B1 (EP)
Inventor: ALTEN KURT
IPC: A47H23/00
Filed: 1991-09-12
Granted: 1995-02-15
Abstract: The invention relates to a deformable seal for the gap between the edge of an opening in a building and the tail of a vehicle drawn up to said opening, in which a deformable apron having a transverse part arranged at the top and vertical strips situated at both sides of the building opening is provided. To improve the sealing action and to save energy, the invention proposes that there be provided in the region of the lower end of the vertical strips (6) a further transverse part (7) as a component of the flexible apron, said component being connected to a flexible supporting body (10). 
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Patent EP-0476574-B1 (EP)
Inventor: CHMELIR MIROSLAV DR
IPC: C08F2/44
Filed: 1991-09-17
Granted: 2001-05-23
Abstract: Production of an absorption material for water, aqueous solutions or bodily fluids from a water-swellable synthetic (co)polymer (A) and a natural or synthetic polymer (B) which is a flowable powder at normal temperatures and which is insoluble or only difficultly soluble in water comprises adding dry or partly swollen (B) to the production system for (A) at a conversion to (A) of ≥ 30 (especially ≥ 60)%, mixing with polymer (A) gel and then drying the product.
Patent EP-0483683-B1 (EP)
Inventor: NAKA TAKEHIKO
IPC: C07D495/04
Filed: 1991-10-25
Granted: 1996-02-28
Abstract: Benzimidazole derivatives of the formula (I): <CHEM> wherein the ring A is a thiophene ring which may optionally contain substitution in addition to the R<3> group; R<1> is hydrogen or optionally substituted hydrocarbon residue which may be bonded through a hetero atom; R<2> and R<3> are independently a group capable of forming an anion or a group convertible thereinto; X is a direct bond or a spacer having an atomic length of two or less between the phenylene group and the phenyl group; and n is an integer of 1 or 2; or a salt thereof, have potent angiotensin II antagonistic activity and antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc.
Patent EP-0489465-B1 (EP)
Inventor: SHIGEKAWA BRIAN LAYNE
IPC: C07C323/52
Filed: 1991-12-01
Granted: 1996-09-04
Abstract: Gold sol coated with alkanethiols and alkanethiol derivatives, which provide groups on the sol available for the linking of binding moieties such as antibodies, antigens or ligands to the gold sol. Di- and tri-thiol compounds bound to gold sol also facilitate the adsorption of antibodies, antigens or ligands to the sol. The coating process, and test kits incorporating the coated sols are also included.
Patent EP-0491507-B1 (EP)
Inventor: JOHNSON PETER E
IPC: H01M10/04
Filed: 1991-12-05
Granted: 1995-04-26
Abstract: Battery plates from the high speed output conveyor (12) of a pasted plate making machine are deposited onto a lower speed first conveyor (10) in an overlapped fashion to create a shingled stream of plates (18). As plates drop off of the discharge end (19) of the first conveyor (10) they are accumulated in vertical stacks (31) on a second conveyor (24) that is located below the first conveyor (10). Whenever a stack (31) is completed the second conveyor (24) is moved approximately one plate width to remove the stack and the process continues. In order to provide time to move the stack, the flow of plates (18) on the first conveyor (10) is disrupted when the stack (31) is being moved. In the preferred embodiment the disruption is caused by squeezing the plates between the jaws (38, 42) of a clamping mechanism (36) that the plates pass through. A counter (20) is used to count the number of plates in a stack and a controller (22) causes the clamping mechanism (36) to be engaged at the proper time, causes the second conveyor (24) to remove the just-formed stack and then causes the second conveyor (24) to stop and the clamping mechanism to be reopened so that a second stack can be formed. A gate (32) extends across the second conveyor (24) when the stack is being formed to ensure that the stack is straight. The gate (32) is raised upon command from the controller (22) when movement of the second conveyor (24) commences and is lowered again when movement of the second conveyor ceases. <IMAGE>
Patent EP-0457693-B1 (EP)
Inventor: COCCO ROGER
IPC: C08G77/18
Filed: 1991-04-23
Granted: 1994-03-02
Abstract: Process for the preparation of diorganopolysiloxanes with alkoxy end groups in the presence of a catalyst chosen from sodium hydroxide and potassium hydroxide. Use of these diorganopolysiloxanes for the preparation of single-component polysiloxane compositions which are stable in storage in the absence of moisture and which crosslink to elastomer in the presence of moisture.
Patent EP-0453401-B1 (EP)
Inventor: SUTER BRUNO
IPC: A47B85/02
Filed: 1991-04-09
Granted: 1996-01-03
Abstract: A height adjustable frame (1) is provided, with respect to which the inclination of a plate holder (3) may be adjusted around a support axis (H). The plate holder (3) may be pivoted with the plate (4) from its vertical resting position into a horizontal or inclined working position. The plate sections (41) may be brought into the working position with the plate (4) on the front and/or rear edge (31) by means of pivoting (S) the plate holder (33), the said sections also being pivoted about the plate axis (P) into the specifically desired display or working position. Height and inclination adjustment in this manner enables optimum adjustment of the display and work table to suit requirements. <IMAGE>
Patent EP-0526453-B1 (EP)
Inventor: MICKAL HERMANN
IPC: H02M7/48
Filed: 1991-01-24
Granted: 1994-12-28
Abstract: L'invention concerne un procédé pour l'exploitation d'un onduleur comportant n éléments de réglage (2, 4, 6) fonctionnant en parallèle et constitué chacun de m vannes de convertisseur (Tln, ..., Tmn, ces n éléments de réglage (2, 4, 6) étant alimentés, du côté entrée, par une source commune de courant continu (UZ) et reliés entre eux, du côté sortie, au moyen d'un transformateur (10) avec un circuit de condensateurs de filtrage (12) en amont, ainsi qu'un circuit pour la mise en ÷uvre du procédé. Dans l'invention, la totalité des m signaux de commande (UATl, ..., UATm) produits sont amenés ensemble jusqu'à n vannes de convertisseur fonctionnant en parallèle (Tl1, Tl2, ..., Tln ou ... ou Tm1, Tm2, ..., Tmn) des n éléments de réglage (2, 4, 6), un signal de libération (UFSl ou ... ou UFSm) est produit à chaque fois à l'instant précis où chacune des n vannes de convertisseur fonctionnant en parallèle (Tl1, Tl2, ..., Tln ou ... Tm1, Tm2, ..., Tmn) produit un signal de sortie (Uoff11, Ioff12, ..., Uoffln ou ... ou Uoffm1, Uoffln) et chaque signal de libération produit (UFSl ou ... ou UFSm) donne un signal de commande (UATl, ou ... ou UATm) pour n vannes de convertisseur (Tl1, Tl2, ..., Tln ou ... ou Tm1, Tm2, ..., Tmn) fonctionnant en parallèle et établissant un circuit complémentaire. On obtient ainsi un onduleur comportant uniquement un circuit de régulation et de commande (8) pour n éléments de réglage (2, 4, 6), le courant de charge étant symétriquement réparti sur les n éléments de réglage (2, 4, 6).
Patent EP-0525114-B1 (EP)
Inventor: CHENG WEI T
IPC: B41J27/20
Filed: 1991-04-12
Granted: 1995-10-11
Abstract: A printer cartridge including a leak resistant ink reservoir, a wicking mechanism and an inking apparatus. The reservoir is for a predetermined quantity of ink and resists leakage by an arrangement of venting and dispensing apertures arranged and provided with barriers. The wicking mechanism combines compressible capillary tubing with an applicator, so that pressure on the applicator squeezes the capillary tubing to provide both pumping and capillary transfer of ink from the reservoir to the applicator. The inking apparatus intermittently presses against the applicator to pick up a film of ink and to provide the pumping action for the wicking mechanism. The inking apparatus includes two belts that receive ink from the applicator and apply it to upper and lower zones of a printer ribbon. The ink is then allowed to diffuse into the central impact zone of the ribbon.
Patent EP-0544810-B1 (EP)
Inventor: LAUGHNER MICHAEL KENNETH
IPC: C08L73/00
Filed: 1991-08-15
Granted: 1995-01-18
Abstract: Thermoplastic molding composition containing a polycarbonate, a polyester, an olefin/carbon monoxide copolymer, a mono-alkenyl aromatic/diene block copolymer, such as a styrene/butadiene/styrene block copolymer, and a grafted core-shell elastomer, such as a methacrylate/butadiene/styrene copolymer. Compositions containing all five of the aforesaid components possess superior impact strength and solvent resistance as compared to compositions containing polycarbonate, polyester and an olefin/carbon monoxide copolymer, and either a mono-alkenyl aromatic/diene block copolymer or a grafted core-shell elastomer, but not both.
Patent EP-0554292-B1 (EP)
Title: Emulsions d'huile dans l'eau
Inventor: KAWA ROLF
IPC: C09K23/56
Filed: 1991-10-16
Granted: 1994-12-21
Abstract: Des émulsions d'huile dans l'eau contiennent un ou plusieurs corps gras insolubles dans l'eau, de l'eau et un ou plusieurs glucosides d'alkyle qui servent d'émulsifiants, ainsi qu'un glycéride partiel d'acides gras qui sert d'inhibiteur de la cristallisation. Ces émulsions se caractérisent par une bonne stabilité au stockage. On peut en outre composer des concentrés d'émulsifiants à base de glucosides d'alkyle et de glycérides partiels d'acides gras, qui sont utiles pour produire des émulsions d'huile dans l'eau stables au stockage.
Patent EP-0526589-B1 (EP)
Title: Filtre a ondes de surface et a faibles pertes
Inventor: DUFILIE PIERRE
IPC: H03H9/145
Filed: 1991-04-12
Granted: 1994-06-22
Abstract: Filtre hyperfréquences à ondes acoustiques de surface et à faibles pertes, du type comportant des transducteurs d'entrée (2, 3) et de sortie (4, 5), associés acoustiquement à des transducteurs de couplage (6, 7). Les positions relatives des transducteurs (2 à 7) et de leurs réflecteurs en O sont choisies, compte tenu des pondérations des transducteurs de couplage (6, 7) pour obtenir, pour ce filtre, la fonction de transfert souhaitée.
Patent EP-0528238-B1 (EP)
Inventor: BIESEL WOLFGANG DR
IPC: A61M1/36
Filed: 1992-08-01
Granted: 1995-11-08
Abstract: In a device (10) for separating blood the haematocrit value of the blood to be separated plays an important role for sedimentation of cellular blood constituents. Due to the fact that considerable fluctuations of the baseline haematocrit value of the blood may occur, especially in the intraoperative field, during processing of blood, for example as a result of infused volume expanders, irrigation solutions, added anticoagulants and the like, it is expedient to include the predetermined haematocrit value of the blood to be separated in the separation process, in order to maintain the blood separation at constant values, in particular with a constant haematocrit value of the erythrocyte fraction. According to the invention, the amount of blood flowing through the separating device (10) is automatically adjusted as a function of the haematocrit value of the blood supplied. 
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Patent EP-0500360-B1 (EP)
Inventor: BELLEY MICHEL L
IPC: A61P1/16
Filed: 1992-02-20
Granted: 1997-06-25
Abstract: Compounds having the formula I: <CHEM> are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection.
Patent EP-0528647-B1 (EP)
Inventor: PIES JOHN R
IPC: B41J2/14
Filed: 1992-08-13
Granted: 1996-12-11
Abstract: An ink jet printhead (10) for a drop-on-demand type ink jet printing system. The printhead includes a base section (12) having a series of generally parallel spaced projections (30) extending longitudinally therealong, a series of intermediate sections (32) conductively mounted on a top side of a corresponding one of the series of base section projections (30) and a top section (16) conductively mounted to a top side of each of the series of intermediate sections (32). <IMAGE>
Patent EP-0539240-B1 (EP)
Inventor: YUASA HAJIME C O AKISHIMA LAB
IPC: E21B47/13
Filed: 1992-10-26
Granted: 1997-08-06
Abstract: A bottom-hole information collecting equipment to collect data at the bottom part of the shaft in real time by means of the sonde throughout an excavation by the bit for digging. The sonde is provided to be mechanically and electronically connected to or separated from the connecting pipe to which the bite is attached arbitrarily. Data collected by several sensors near the bit is transmitted to the sonde via the electromagnetic coupler. The electricity for the sensors and the sonde can be obtained by respective generators of which one is in the sonde and the other is in the connecting pipe. <IMAGE>
Patent EP-0533573-B1 (EP)
Inventor: KUO ELIZABETH ANNE
IPC: A61P29/00
Filed: 1992-09-17
Granted: 1996-12-04
Abstract: The invention relates to new 3-cycloalkyl-2-propenamide derivatives of formula (I): 
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 in which 
 
  R1 represents H or (C1-C3)alkyl, 
  W represents O or optionally oxidised S, 
  Y and Z represent -CH- or one of Y and Z represents -CH and the other represents N, 
  R2, R3, R4, R5 and R6 represent H, halogen, (C1-C4)alkyl, - OCH3, -SCH3, -WCF3, NO2, CN, -W(CH2)n-CF3, -W(CF2)n-CF3 , -(CH2)n-CX3 or -(CF2)n-CF3, in which n is 1, 2 or 3 and X represents halogen or R3 and R4 together form -O-CH2-O-, 
  R7 and R8 represent H or (C1-C6)alkyl, 
  R9 represents (C3-C6)cycloalkyl, 
 to their tautomeric forms and to their addition salts with bases, as well as to their process of preparation, to their application as medicaments and to the compositions which contain them.