baber/WOPTO huggingface dataset:
Patent UY-33229-A (UY)
Title: Derivados de piridina tricíclicos, medicamentos que contienen tales compuestos, su uso y proceso pa ra su preparación
Inventor: THOMAS TRIESELMANN
IPC: A61K31/4741
Filed: 2011-02-17
Abstract: La presente invención se refiere a compuestos derivados de 1,3,6,7,8,9-hexahidro-furo[3,4-c]quinolina de fórmula I en la que las variables R1-R8 se definen como en la descripción, que poseen actividad farmacológica valiosa. Particularmente, los compuestos son inhibidores de la proteína de transferencia de éster de colesterol (CETP) y, por lo tanto, son adecuados para el tratamiento y prevención de enfermedades que pueden influenciarse por la inhibición de esta enzima.
Patent UY-34199-A (UY)
Inventor: THOMAS HOFFMAN
IPC: C12N15/29
Filed: 2012-07-13
Abstract: NO IMAGE
Patent UY-35906-A (UY)
Title: Novedosos derivados de bencimidazol como ligandos de ep4
Inventor: ULRICH BOTHE
IPC: C07D403/02
Filed: 2014-12-19
Abstract: La presente invención se refiere a novedosos derivados de bencimidazol de la fórmula general (I), a procedimientos para su preparación, así como su uso para la preparación de agentes farmacéuticos para el tratamiento de enfermedades e indicaciones que están relacionadas con el receptor EP4.
Patent UY-39362-A (UY)
Title: Materiales y métodos para la biotransportación multidireccional en viroterapia
Inventor: SINGH SANJAYA
IPC: C12N15/85
Filed: 2021-08-02
Abstract: En el presente documento se proporcionan moléculas multiespecíficas que comprenden un primer dominio de unión que se une específicamente al receptor de inmunoglobulina polimérico (pIgR) y un segundo dominio de unión que se une específicamente al síndrome respiratorio agudo severo coronavirus 2 (SARS-CoV-2) y métodos relacionados para el tratamiento de pacientes. infectado con SARS-CoV-2.
Patent UY-39396-A (UY)
Title: Vacuna basada en aav5 para la inducción de inmunidad específica contra el sarscov-2 y/o la prevención de la infección por coronavirus relacionada con el sarscov-2
Inventor: MOROZOV DMITRY VALENTINOVICH
IPC: C12N15/85
Filed: 2021-08-27
Abstract: Esta invención refiere a un dominio de unión a receptor recombinante aislado de la glicoproteína S (RBD-S) de SARS-CoV-2, a un ácido nucleico que codifica RBD-S de SARS-CoV-2, a un casete de expresión y un vector basado en el mismo, a un virus basado en AAV5 recombinante (virus adenoasociado serotipo 5) para la inducción de inmunidad específica al SARS-CoV-2 y / o la prevención de dicha infección, a un AAV5 -vacuna basada en la inducción de inmunidad específica al SARS-CoV-2 y / o prevención de la infección por coronavirus relacionada con el SARS-CoV-2.
Patent YU-57500-A (YU)
Title: (4-arylsultonylamino)-tetrahydropyran-4-carboxylic acid hydroxamides
Inventor: REITER LAWRENCE ALAN
IPC: A61P17/02
Filed: 1999-03-24
Abstract: A compound of formula (I) wherein Q is as defined, is use in the treatment of a condition selected from the group consisting of arthritis (including osteoarthritis and rheumatoid arthritis), inflammatory bowel disease, Crohn's disease, emphysema, chronic obstructive pulmonary disease, Alzheimer's disease, organ transplant toxicity, cachexia, allergic reactions, allergic contact hypersensitivity, cancer, tissue ulceration, restenosis, periodontal disease, epidermolysis bullosa, osteoporosis, loosening of artificial joint implants, atherosclerosis (including atherosclerotic plaque rupture), aortic aneurysm (including abdominal aortic aneurysm and brain aortic aneurysm), congestive heart failure, myocardial infarction, stroke, cerebral ischemia, head trauma, spinal cord injury, neuro-degenerative disorders (acute and chronic), autoimmune disorders, Huntington's disease, Parkinson's disease, migraine, depression, peripheral neurophaty, pain, cerebral amyloid angiopathy, nootropic or cognition enhancement, amyotrophic lateral sclerosis, multiple sclerosis, ocular angiogenesis, corneal injury, macular degeneration, abnormal wound healing, burns, diabetes, tumor invasion, tumor growth, tumor metastasis, corneal scarring, scleritis, AIDS, sepsis and septic shock. In addition, the compounds of the present invention may be used in combination therapy with standard non-steroidal anti-inflammatory drugs (NSAID'S) and analgesics, and in combination with cytotoxic drugs such as adriamycin, daunomycin, cis-platinum, etoposide, taxol, taxotere and other alkaloids, such as vincristine, in the treatment of cancer.
Patent AT-A165486-A (AT)
IPC: E05D7/00
Filed: 1986-06-18
Abstract: The door hinge has a first hinge part (1) for attachment to a door wing, a second hinge part (2) for attachment to a door frame and an axle bolt (6) forming the axis of rotation. The axle bolt (6) is provided with a threaded part (7), with which it is screwed into a threaded nut (10) in a recess (9) in the hinge part (1) in a height-adjustable manner. Approximately in the centre, the axle bolt (6) has engagement means (13) for an adjustment tool, for example a spanner. Seated on the threaded part (7) is a check nut (14) which rests on the hinge part (1), into which the threaded part (7) is screwed.
Patent BE-894870-A (BE)
Title: Method of underground working - has open trench first dug ahead of face and sealed enclosure later covered over
IPC: E02D29/05
Filed: 1982-10-29
Abstract: The method is for making an underground tunnel, in water bearing ground. An open trench is first dug (5), then, in this, the walls (1) are built and the trench is finally closed in whilst the trench is dug. Downstream, a face is moved up. With this is a prefabricated enclosure (1,2) which is virtually sealed. The procedure is to move the face and dig the trench at the same time. The progress of the digging machine and face (6) is the same as that of trenching operations.
Patent BE-899200-A (BE)
Title: Marteau perforateur electropneumatique.
Inventor: LIPPACHER WOLFGANG
IPC: B25D16/00
Filed: 1984-03-20
Abstract: L'invention concerne un marteau perforateur électropneumatique comportant un cylindre de guidage (8) pour un piston d'actionnement (14) ainsi qu'un piston de percussion (15); un arbre creux (19) entourant le cylindre de guidage (8) et servant à transmettre le mouvement de rotation à un outil est monté sur le cylindre de guidage (8); le cylindre de guidage (8) comporte à son extrémité arrière des paliers (8a, 8b) pour un vilebrequin (9) assurant un mouvement oscillant du piston d'actionnement (14) par l'intermédiare d'une bielle (12).
Patent BE-899278-A (BE)
Title: Agent antimycotique a haute liberation de substance active sous forme d'une creme.
IPC: A61K47/44
Filed: 1984-03-29
Abstract: Des crèmes qui contiennent du Bifonazol comme substance active avec 10-60% d'un agent d'étendage et 20-80% d'un solvant, exercent une bonne activité antimycotique et peuvent etre utilisées comme médicaments.
Patent BE-899921-A (BE)
Title: Huile de laminage a froid de toles d'acier.
Inventor: TOHMATA EISUKE
IPC: C10N40/24
Filed: 1984-06-15
Abstract: Huiles de laminage à froid de toles d'acier caractérisées en ce qu'il est ajouté un composé cationique de haut poids moléculaire et de 0,1 % à 5 % d'un surfactif non ionique ayant une valeur HLB de 12 ou une valeur HLB supérieure à 12 (HLB = balance of the hydrophilic groups and the lipophilic groups 0 équilibre entre les groupes hydrophiles et les groupes lipophiles) pour chaque huile de laminage, en tant qu'agents de mise en émulsion et en dispersion. Ces huiles présentent un excellent pouvoir de lubrification, une excellente stabilité de lubrification et la propriété de constituer des huiles fraiches.
Patent BE-900033-A (BE)
Title: Dispositif a fixer a un vehicule pour en modifier les caracteristiques aerodynamiques et son procede de fabrication.
Inventor: LOREN N
IPC: B62D37/02
Filed: 1984-06-28
Abstract: Aileron pour véhicule constitué de deux moitiés moulées par injection et renfermant un noyau en mousse de matière plastique. Les deux moitiés (22, 24) forment une coque (18) remplie d'une mousse (25) de matière plastique qui accroit la rigidité de la coque et obture les interstices (28) formés entre les bords d'assemblage des deux parties de la coque. Domaine d'application : ailerons aérodynamiques et décoratifs pour véhicules, etc.
Patent BE-900774-A (BE)
Title: Agent d'epreuve pour la detection d'une substance dans un liquide corporel.
Inventor: KAMINAGAYOSHI S
IPC: G01N33/50
Filed: 1984-10-08
Abstract: Agent d'épreuve pour détecter un hydroperoxyde (ou le peroxyde d'hydrogène) ou pour détecter une peroxydase, qui comprend un agent chromogène susceptible d'etre oxydé et de virer de coloration sous l'influence de la réaction du peroxyde ou de la peroxydase, outre une quantité chimiquement efficace d'au moins un antioxydant qui est de formule MIXO, MIXO3, MIXO4 ou MI3H2XO6, (où Mi représente un atome formant un cation monovalent et X représente un atome d'halogène) où qui est un sel tel que le sulfate cuivrique.
Patent BE-901205-A (BE)
Title: Embout pour cigarette et cigarette equipee de cet embout.
Inventor: RIEHL T F
IPC: A24D1/04
Filed: 1984-12-04
Abstract: L'embout (10) comporte un noyau central imperméable à l'air (14) de diamètre inférieur au boudin de tabac (12) sur lequel il est fixé coaxialement et un manchon creux cylindre (20) de meme diamètre que le boudin de tabac, concentrique au noyau et coopérant  avec lui pour définir un canal annulaire (22). L'embout est relié au boudin de tabac par une manchette perméable  à l'air les entourant. Dans une variante, l'embout comporte un tampon filtrant, intercalé entre le boudin et le manchon, pourvu de rainures longitudinales qui débouchent dans le canal annulaire précédent.
Patent BE-904271-A (BE)
Title: Poignee rotative placee sur un dispositif d'ecoulement et de tropplein pour baignoire.
Inventor: EGLI ANTON
IPC: E03C1/232
Filed: 1986-02-24
Abstract: La poignée rotative (20) comprend un entraineur en forme d'assiette (1) qui est fixé sur une tige d'actionnement (10). Sur la paroi latérale de l'entraineur (1) sont prévues des pattes élastiques (3) qui sur leurs faces externes présentent des aretes surélevées (19). Sur l'entraineur (1) est montée une rosette (2) qui comprend sur sa face externe une contre-dépouille (5) dans laquelle les pattes (3) sont engagées de manière amovible. La rosette (2) peut etre retirée sans outil auxiliaire pour le nettoyage et peut etre de nouveau mise en place par un légère pression axiale.
Patent CA-1036304-A (CA)
Inventor: WATANABE SADAYOSHI
IPC: D21C3/00
Filed: 1974-04-30
Granted: 1978-08-15
Abstract: A B S T R A C T There is disclosed a process for producing paper-making pulps form grasses.  The process comprises impregnating a grass in the form of chips with a 0.5 to 6% by weight aqueous solution of alkali at a temperature of 10 to 100°C., compressing the grass to remove an excess aqueous solution so as to provide a wet mass of grass, loosening the wet mass to provide a porous mass of grass, treating the porous mass with an oxygen-containing gas at a temperature of from about 60°C to about 130°C., and then washing the resulting pulp with water and drying it.
Patent CA-1046490-A (CA)
Inventor: REMEIKA JOSEPH P
IPC: B01J23/89
Filed: 1974-05-03
Granted: 1979-01-16
Abstract: Abstract of the Disclosure The specification discloses a catalyst for oxidation and reduction reactions containing a perovskite-like manganite of the formula RE1-xMxMnO3, in which RE is one or more rare earth elements selected from the group La, Pr, and Nd; M is one or more elements selected from the group Na, K, and Rb; and x is from 0.1 to 0.4.  Any of the indicated cations may be reduced by up to about 15 atom percent to accommodate vacancy structures.  The catalysts are particularly useful for the removal of NOx from automobile emissions in order to prevent air pollution.
Patent CA-1053823-A (CA)
Inventor: TRAVER FRANK J
IPC: B05D5/08
Filed: 1974-06-24
Granted: 1979-05-01
Abstract: ABSTRACT OF THE DISCLOSURE           A preformulated inside green tire lubricant and bag release composition comprising a silicone fluid, an alkylene oxide polyol; a particulate solid for providing air bleed channels between the expanding pressure core and the green tire; water; and sufficient suspending and emul-sifying agents to provide a stabilized, non-settling suspension.
Patent CA-1047687-A (CA)
Inventor: KATO YASUO
IPC: C08G63/00
Filed: 1974-09-06
Granted: 1979-01-30
Abstract: Abstract of the Disclosure: A fireproof polyester having a high stability to ultraviolet rays and heat, which is characterized in that the unit of a bromine compound of the formula:                               wherein R1 and R2 are each a substituted or unsubstituted alkylene group having 1 to 5 carbon atoms and n1 and n2 are each an integer of 0 to 4 is contained in the molecular chain.
Patent CA-1055163-A (CA)
Title: Method and circuit for determining voltage and current values associated with given switch-on durations of an x-ray source
Inventor: SMITS WIGLE F
IPC: H05G1/30
Filed: 1974-10-09
Granted: 1979-05-22
Abstract: ABSTRACT OF THE DISCLOSURE:                      Determination of the voltage and current values for an X-ray source by choosing a point of intersection with the lowest voltage value of an operating range limitation function of the X-ray source with a current-voltage function passed through the current-voltage coordinates of a desired current value determined by an exposure measurement.
Patent CA-1049694-A (CA)
Title: Polyesteramines a affinite tinctoriale amelioree et leur procede d'obtention
Inventor: VAGINAY YVES
IPC: D06P3/52
Filed: 1974-10-11
Granted: 1979-02-27
Abstract: La présente invention concerne des polyesteramines de bonne affinité tinctoriale vis-à-vis des colorants anioniques ainsi que leur procédé d'obtention.  Ils sont issus de : au moins un diacide aromatique et éventuellement d'une faible quantité d'un diacide aliphatique, au moins un diol aliphatique, cyclanique, cycloaliphatique, possédant au moins trois atomes de carbone dans la molécule, au moins un composé de formule NR3 dans laquelle les radicaux R, identiques ou différents, représentent des groupes alcoyle, cyclaniques, cycloalcoyle ou arylaliphatiques, un, deux ou trois groupes R portant un, deux ou trois groupements générateurs d'ester, le nombre de groupes générateurs d'ester étant de 1 à 3 inclus, deux des groupes R pouvant former entre eux un cycle mais pas plus de deux radicaux R étant des radicaux arylaliphatiques ou cycloaliphatiques comportant un seul atome de carbone entre le cycle et l'atome d'azote, ou des radicaux cyclaniques et dans laquelle le nombre d'atomes de carbone compris entre le ou les groupes générateurs d'esters et l'atome d'azote est au moins égal à 3, le(s) dit(s) composé(s) étant utilisé(s) en proportion telle que le pourcentage d'azote fixé sur le polymère soit d'au moins 0,03 % en poids par rapport au polymère; et le ou le(s) dit(s) composé(s) sont ajoutés après le moment où au moins 90 % en poids du méthanol théoriquement produit sont éliminés du milieu réactionnel.  Les fils à base de polyesteramine selon l'invention sont avantageusement utilisés dans de nombreux domaines textiles.
Patent CA-1048704-A (CA)
Inventor: EGAN FRANCIS L JR
IPC: A44B99/00
Filed: 1975-02-03
Granted: 1979-02-20
Abstract: A B S T R A C T      A diaper fastener comprises an elongated strip of tape having an adhesive coated surface and a web adhesively secured to said surface in the longitudinally central portion of said strip of tape, the exposed surface of said web having limited affinity for said adhesive.  The adhesive coated sur-face in one end portion of said strip of tape is in contact with said web exposed surface.  The web has an opening therethrough whereby region of adhesive in said end and central portions aligned with said opening re? contact for releasably securing said end portion.
Patent CA-1046393-A (CA)
Inventor: STIGEN MERRITT L
IPC: C09J7/10
Filed: 1975-03-18
Granted: 1979-01-16
Abstract: ABSTRACT             Embossable label tape laminate has a light-embossed and an underlying flexible magnet-particle layer by which labels served from the tape laminate can be magnetically adhered to ferromagnetic objects.  Characters can be embossed in the magnetic tape laminate using an ordinary tape-embossing gun.
Patent CA-1059665-A (CA)
Inventor: VAN DEURSEN THEODORUS H M
IPC: H03J7/18
Filed: 1975-09-30
Granted: 1979-07-31
Abstract: ABSTRACT                The use of group classification in a memory containing tuning data for a receiver and a scanning group selector giving a possibility of performing a selectable search per group of tuning data increases ease of operation.
Patent CA-1075121-A (CA)
Inventor: SPASIANO ANTHONY D
IPC: A61B17/128
Filed: 1975-10-07
Granted: 1980-04-08
Abstract: A B S T R A C T     A surgical instrument for controlling the operation of a three-stage staple-carrying cartridge adapted to ligate, suture and divide organic tubular structures such as blood vessels.  The instrument also operates in three stages to positively control the ligating, suturing and dividing operations of the cartridge. the cartridge actuating mechanism takes the form of three saddles which are, in turn, controlled by the operating mechanism of the instrument.  A two-link mechanical toggle positively controls the operation of two of the three cartridge-actuating saddles.  The third saddle is, in turn, controlled by a shifter dog mechanism.          The instrument is also equipped with a mechanism which ensures the completion of a ligating, suturing and dividing cycle to avoid jamming the staple-carrying cartridge.
Patent CA-1053709-A (CA)
Inventor: GARVIE RONALD C
IPC: C04B35/486
Filed: 1975-10-23
Granted: 1979-05-01
Abstract: ABSTRACT OF THE DISCLOSURE       This specification discloses partially stabilizes zirconia (zirconium oxide, ZrO2) ceramic refractory materials (referred to as PSZ ceramics) and more particularly relates to specific ceramic compositions, within a known range of compositions, which possess markedly improved properties when compared with known ceramic materials.  The specification discloses such an improved calcia-partially-stabilized zirconia ceramic material which contains 3.3 and 4.7 per cent of calcia by weight.  In one aspect, the specifica-tion discloses a touch, refractory ceramic comprising essentially a calcia-partially-stabilized zirconia body, characterized in that the calcia concentration lies within the range 3.3 - 4.7 per cent by weight of the ceramic body, and in that said body has a fine-scale two-phase microstructure substantially consisting of a metastable tetragonal domains of a critical size within cubic matrix grains.  These domains, in regions of high stress, irreversibly transform to normal monoclinic form upon stressing of the body. Uses for the materials of this invention include extrusion dies for metals, particularly for copper, brass and stainless steel; blow-out orifices for continuously operating high-temperature, high-pressure autoclaving processes; high temperature bearings and metal cutting tool bits.
Patent CA-1036934-A (CA)
Inventor: BOND EDWIN J
IPC: A01N37/34
Filed: 1975-11-12
Granted: 1978-08-22
Abstract: ABSTRACT   This invention gives the components of a mixture and provides a method for fumigating space, bulk storage or soil by means of a mixture of methyl bromide and acrylonitrile or other nitrile compounds per se or dissolved in a carrier to control insects and related organisms.  The method is effective over temperatures ranging up to and above 50°C and down to and below -10°C.
Patent CA-1065825-A (CA)
Inventor: BRADBURN RONALD G
IPC: B02C25/00
Filed: 1976-01-19
Granted: 1979-11-06
Abstract: METHOD AND SYSTEM FOR MAINTAINING OPTIMUM THROUGHPUT IN A GRINDING CIRCUIT ABSTRACT OF THE DISCLOSURE:           A method and a system are disclosed for maintaining op-timum throughput in a grinding circuit of the type in which fresh ore is fed to a rod mill and the ground ore from the rod mill, to-gether with the ground ore from a ball mill operated in a reversed circuit, are combined in a pump box and pumped to a cluster of hy-drocyclone classifiers.  The rod mill is operated in open circuit but the ball mill is operated in closed circuit with the cyclone classifiers which serve to classify the mill discharge material, returning the oversize to the ball mill.  The system comprises mo-nitoring devices for sensing the cyclone classifier feed density and any one or combinations of the following conditions of the grinding circuit: 1) rod mill sound, 2) ball mill sound, 3) pump box level, and 4) cyclone overflow particle size and density.  A constraint check and decision memory block is connected to the cy-clone classifier feed density monitor and to at least one of the following overload constraints from the above corresponding moni-tors: 1) rod mill overload sound, 2) ball mill overload sound, 3 pump box high level, and 4) cyclone overflow high particle size and high/low density.  A cascade control means is connected to the output of the cyclone classifier feed density monitor and has a control input activated by the constraint check and decision memo-ry block.  A matrix memory block is connected to a fresh ore feed rate monitor and to the rod mill sound monitor and has a control input activated by the constraint check and decision memory block, such matrix memory block being adapted to develop rod mill feed rate setpoints, as a discontinuous function of both the current rod mill feed rate and the rod mill sound.  Finally, a fresh ore feed controller is connected to the output of the cascade control means and the matrix memory block, and operated by either the cascade control means or the matrix memory block depending on which one of the control inputs of the cascade control means and the matrix me-mory block has been activated by the constraint check and decision block.
Patent CA-1058733-A (CA)
Inventor: BLAZEY RICHARD N
IPC: C09K3/00
Filed: 1976-02-13
Granted: 1979-07-17
Abstract: PLASTIC ACOUSTOOPTIC DEVICE              Abstract of the Disclosure A plastic acoustooptic diffraction cell is disclosed.  The cell comprises an unmodified crystal styrene plastic material having an electromechanical transducer bonded thereto for producing acoustic waves in the material.  A heat sink thermally coupled to the transducer series to dissipate thermal energy from the material during acoustic wave propagation.
Patent CA-1084244-A (CA)
Title: Apparatus for distributing particulate material over a reaction zone
Inventor: UHL GEORGE A
IPC: B01J4/00
Filed: 1976-03-25
Granted: 1980-08-26
Abstract: APPARATUS FOR DISTRIBUTING PARTICULATE               MATERIAL OVER A REACTION ZONE                    ABSTRACT OF DISCLOSURE           An improved apparatus for distributing particulate material, e.g., comprising catalyst particles, over a zone, e.g., chemical reaction zone, wherein the apparatus is not centrally located with respect to the zone, comprising: a supply hopper, having inlet means and outlet means, for holding particulate material; a deflection plate located adjacent to the end of the outlet means away from the supply hopper to deflect the direc-tion of at least a portion of the  particulate material flowing through the outlet means; at least two conduits in fluid communication with at Least one source of gaseous media, each of the conduits being situated such that at least a portion of the gaseous media from the conduits flows in the space between the end of the outlet means away from the supply hopper and the deflection plate to thereby cause at least a portion of the particulate material to be propelled in substantially the same direction as the flow, provided that the gaseous media is expelled from at least two of the conduits at different, predetermined flowrates so that the particulate material is substantially uniformly distributed over the zone.         An improved method for distributing particulate material in a zone has also been discovered.