baber/WOPTO huggingface dataset:
Patent CA-2966714-A1 (CA)
Title: Dexamethasone oral film
Inventor: WESTRIN BENGT ARVID
IPC: A61P1/08
Filed: 2015-11-04
Abstract: The present invention relates to an oral film consisting essentially of dexamethasone and hydroxypropyl methylcellulose, wherein the concentration of dexamethasone is 30% w/w or more and the concentration of hydroxypropyl methylcellulose is between 35 and 70% w/w based on total dry matter.
Patent CA-2969658-A1 (CA)
Title: Fin-based watercraft propulsion system
Inventor: GARTHWAITE MARTIN
IPC: B63H1/36
Filed: 2014-12-04
Abstract: A watercraft comprises a motor, an inertial mass, and a fin. The motor oscillates the inertial mass about an axis, producing a torque reaction on and oscillation of the motor. Oscillation of the motor is communicated to the fin, producing thrust.
Patent CA-2969716-A1 (CA)
Inventor: JARRETT PETER
IPC: A61K9/10
Filed: 2015-12-10
Abstract: Materials and methods for treating a patient, optionally a patient with an eye disease, comprising providing a collection of particles that comprise a first biodegradable material that is a hydrogel or a xerogel and a therapeutic agent, with the first material, before biodegradation, having a rate of release for the therapeutic agent as measured in physiological solution, and forming a second hydrogel ex vivo or in situ on a tissue of the patient at a site of intended use, optionally at or near an eye, that at least partially coats the collection of particles. The agent is released to treat the patient.
Patent CA-2969983-A1 (CA)
Inventor: BLOMME MACLEAN
IPC: A41B13/10
Filed: 2017-06-02
Abstract: A combination comprising a baby bib and at least a pair of suction cups is provided, the combination for releasably affixing to a surface, the bib comprising: a sheet portion, the sheet portion having a proximal end, and a distal end; a pair of sleeves extending from the sheet portion in a vicinity of the proximal end and extending therefrom, the proximal end of the sheet portion defining a neck; a neck closure for providing an opening when closed; and at least two apertures located in a vicinity of the distal end, each suction cup including a cup with a threaded post extending therefrom, a cap with a central opening for accepting the threaded post, and a screw cap threadedly engaging the threaded post, the cup located on an underside of the sheet portion, the threaded post extending through the aperture and the central opening of the cap, the cap sitting on an upper surface of the sheet portion and the screw cap threadedly, releasably retaining the threaded post. A method of protecting a baby from spills is also provided.
Patent CA-2970280-A1 (CA)
Inventor: WANG QIONG J
IPC: A61K35/76
Filed: 2015-04-09
Abstract: The invention provides a chimeric antigen receptor (CAR) having antigenic specificity for CD70, the CAR comprising: an antigen binding - transmembrane domain comprising a CD27 amino acid sequence lacking all or a portion of the CD27 intracellular T cell signaling domain; a 4-1BB intracellular T cell signaling domain; a CD3? intracellular T cell signaling domain; and optionally, a CD28 intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.
Patent CA-2971146-A1 (CA)
Inventor: KOHLIK KAREL
IPC: E21B43/24
Filed: 2015-12-17
Abstract: Method of simultaneous introducing of two or more than two chemical substances and/or water into a subterraneous hydrocarbon formation and/or control of the rate of chemical reactions of these substances, and a device for implementation of this method This invention relates to the method of simultaneous introducing of two or more than two chemical substances and/or water into a subterraneous hydrocarbon formation and/or control of rate of chemical reactions of these substances and/or water by introducing their controlled amount into a subterraneous formation containing liquid and/or gaseous hydrocarbons, particularly crude oil, shale gas or natural, below a dedicated packer for exploration and production of these hydrocarbons and simultaneous inserting of a dedicated data cable (3) for interconnection of the measuring and/or regulating components in the wellbore, where the said chemical substances and/or water are supplied into the wellbore at controlled rate through the free casing (5) by means of at least three mutually separated flexible tubing (2a,b) (flexible injection lines) or the combination of these flexible tubing (flexible injection lines) with the solid wellbore tubing, or by means of at least one flexible multi-channel tubing containing inside at least three fix-attached flexible tubing (channels) of smaller diameter leading into the space in the wellbore and/or pay zone below/behind at least one remotely-adjustable packer connected with the well head that, after reaching the required position, seals off space in the wellbore below the packer and the pay zone (16) against the space above the packer in the wellbore and up to the well head. The invention also includes a device for the implementation of this method.
Patent CA-2971932-A1 (CA)
Title: Methods of producing hydrocarbons from a wellbore utilizing optimized high-pressure water injection
Inventor: DAWSON MATTHEW A
IPC: E21B43/26
Filed: 2015-12-18
Abstract: A method of recovering hydrocarbons from a subterranean formation includes placing a wellbore in the formation, wherein the wellbore is approximately horizontal in the formation; forming one or more fractures in the formation in fluid communication with the wellbore; recovering hydrocarbons from the formation through the wellbore; injecting a volume of fluid comprising greater than 98 mass % water and greater than 0.005 mass % active surfactant into the formation through the wellbore, wherein at least 10 mass% of said volume is injected at a bottom hole pressure at the heel of the wellbore that is less than the minimum horizontal stress in at least a portion of the overburden and at least 5 mass% of said volume is injected at a bottom hole pressure at the heel of the wellbore that is greater than the median minimum horizontal stress in the subterranean formation; and subsequently recovering in situ hydrocarbons from the subterranean formation.
Patent CA-2972324-A1 (CA)
Title: C-19 steroids for inhibiting neovascularization
Inventor: UNTEREGGER GERHARD
IPC: A61P27/02
Filed: 2015-12-21
Abstract: The present invention relates to the field of medicine, particularly to novel uses of C-19 steroid compounds having an androsten-17-(OR4)-3-one structure for inhibiting angiogenesis and particularly the proliferation and/or migration of endothelial cells in the treatment of diseases involving a pathological neovascularization and/or excessive regenerative processes.
Patent CA-2974177-A1 (CA)
Title: Compressed gas energy storage system
Inventor: NARINE SURESH S
IPC: F02C6/16
Filed: 2016-01-19
Abstract: Compressed gas energy storage systems, which include an integrated thermal energy storage component, are provided. The systems include a compression stage, a heat transfer unit, and a gas storage reservoir, serially linked in fluid communication. The system may include one, two, or three compression stages and heat transfer units. Each heat transfer unit may include two or more thermal energy storage stages. Each thermal energy storage stage may include one or more phase change materials. A method of storing compressed gas energy, which includes compressing a gas through a compression stage to produce a compressed gas; passing the compressed gas through a heat transfer unit to produce a heat removed gas; and transferring the heat removed gas to a gas storage reservoir.
Patent CA-2975188-A1 (CA)
Inventor: GOVARI ASSAF
IPC: A61B17/32
Filed: 2017-08-02
Abstract: A surgical apparatus includes a rotatable shaft and a turbine assembly. The rotatable shaft includes a cutter located thereon. The cutter is configured to cut an object when the shaft is rotating about a rotational axis. The turbine assembly includes a turbine and a turbine housing. The turbine housing is configured to receive a fluid that enters the housing parallel to the rotational axis, and to steer the fluid to impinge on the turbine in a direction that is not parallel to the rotational axis. The turbine is configured to rotate the shaft so as to cut the object by the cutter.
Patent CA-2976550-A1 (CA)
Inventor: MENHEERE DAVID
IPC: B64D33/08
Filed: 2017-08-15
Abstract: A cooling system for a gas turbine engine comprises a closed circuit containing a change-phase fluid, at least one heat exchanger configured to receive a first coolant from a first engine system for the change-phase fluid in the closed circuit to absorb heat from the first coolant, whereby the cooling system is configured so that the change-phase fluid at least partially vaporizes when absorbing heat from the at least one heat exchanger. The closed circuit has a cooling exchanger adjacent to an annular wall of a bypass duct, the cooling exchanger configured to be exposed to a flow of cooling air in the bypass duct for the change-phase fluid to release heat to the cooling air and condense at least partially, the cooling exchanger having conduits configured to feed the vaporized change-phase fluid from a heat exchange with the at least one heat exchanger to the cooling exchanger, and to direct condensed change-phase fluid by gravity from the cooling exchanger to the at least one heat exchanger.
Patent CA-2977199-A1 (CA)
Inventor: WARTERSIAN HAROUT
IPC: A46B15/00
Filed: 2016-02-09
Abstract: A self-righting handheld utensil comprises a base having a generally rounded bottom side, and/or a weighted element, which weighted element may be disposed within the base, an elongated region extending outwardly from the base, and a use portion. The weighted element and/or rounded bottom of the base provide for a self-righting function for the disclosed utensil such that, when placed on a flat or substantially flat surface, it counterbalances the utensil to an upright vertical orientation without the need for user intervention or the application of any external force. The base need not become uncoupled from the elongated region and use portion before the user makes use of the disclosed utensil. The base may also have an aesthetic feature on an outer surface thereof, and a portion of the base may comprise one of a flat region and a plurality of spike elements.
Patent CA-2978281-A1 (CA)
Inventor: SABETI MANOUCHEHR
IPC: F16D65/78
Filed: 2016-02-22
Abstract: An arrangement and method for mounting a brake disc to an axle hub of a vehicle is provided. The arrangement includes wedge-shaped holes at an radially inner region of the brake disc, corresponding wedge-shaped key inserts, a retaining device such as a retaining ring, and mounting devices such as bolts or studs and nuts that pass through the retaining ring and keys to bias the keys against the axle hub. The circumferential sides of the wedge shapes are aligned with radial lines extending from the rotation axis of the axle hub. This arrangement and method provides a simple, robust and easily installed brake disc mounting that minimizes heat transfer between the brake disc and the axle hub and accommodates thermal expansion of the brake disc and the axle hub to minimize thermal expansion-induced stresses to the brake disc.
Patent CA-2979414-A1 (CA)
Inventor: FARLEY MARK
IPC: F16K11/085
Filed: 2016-04-06
Abstract: L'invention concerne une soupape pneumatique (300, 710) qui dirige de l'air sous pression vers un instrument chirurgical (104) d'air (730) et qui évacue l'air de cet instrument, tel qu'une sonde vitreuse à double actionnement (750). La soupape pneumatique (300, 710) comprend un corps de soupape symétrique de façon axiale (102, 302), conçu pour tourner d'une première position, dans laquelle la soupape pneumatique (300, 710) place un premier orifice de l'instrument chirurgical (104) en communication fluidique avec l'air sous pression et un second orifice de l'instrument chirurgical (104) en communication fluidique avec l'évacuation d'air (730), vers une seconde position, dans laquelle la soupape pneumatique (300, 710) place le premier orifice en communication fluidique avec l'évacuation d'air (730) et le second orifice en communication fluidique avec l'air sous pression, et pour revenir vers la première position, dans un sens de rotation (320). En tant que tel, le corps de soupape symétrique de façon axiale (302, 304) tourne sans interruption dans un sens de rotation (320) pour alterner l'air sous pression et l'évacuation de l'air (730) entre les deux orifices (322) de l'instrument chirurgical (104) pour commander le fonctionnement à double actionnement (400).
Patent CA-2979482-A1 (CA)
Title: Concentrated natamycin suspension formulations
Inventor: HUANG ZHENGYU
IPC: C12P19/62
Filed: 2016-03-18
Abstract: The present invention generally relates to concentrated natamycin suspension formulations for inhibition of fungal growth. Specifically, the present invention relates to stable suspension concentrate formulations comprising from about 25 % to about 48 % w/w natamycin, from about 0.1 % to about 10 % w/w of an anionic surfactant selected from the group consisting of polyelectrolyte polymers, modified styrene acrylic polymers, dioctyl sodium sulfosuccinates, sodium salts of naphthalene sulfonates, and combinations thereof, and water. The formulations of the present invention contain natamycin as particles which are on average less than 11 microns in diameter and the formulations have a viscosity of less than 1400 centipoise at 21 degrees Celsius.
Patent CA-2982558-A1 (CA)
Inventor: YOON ROE-HOAN
IPC: B01F23/00
Filed: 2016-04-13
Abstract: Hydrophobic particles such as coal and hydrophobized mineral fines can be readily separated from hydrophilic impurities by forming agglomerates in water using a hydrophobic liquids such as oil. The agglomerates of hydrophobic particles usually entrap large amounts of water, causing the moisture of the recovered hydrophobic particles to be excessively high. This problem can be overcome by dispersing the hydrophobic agglomerates in a hydrophobic liquid that can be readily recycled. The dispersion can be achieved using specially designed apparatus and methods that can create a turbulence that can help destabilize the agglomerates in a recyclable hydrophobic liquid and facilitate the dispersion.
Patent CA-2983571-A1 (CA)
Inventor: OSAWA JIRO
IPC: B23C5/12
Filed: 2015-06-15
Abstract: A t-slot cutter (1) that is a tool for cutting a t-groove into a workpiece and that is provided with a body (2A) and an insert part (3). The insert part (3) is affixed to a tip part of the body (2A) by screws (8). The insert part (3) is configured by superimposing inserts (4) and (5). By changing the combination of the inserts that constitute the insert part (3), the groove width and angular shape of the t-groove that is cut into a workpiece can be easily adjusted. At respective mating surfaces of the inserts (4, 5), convexities and concavities of the mating surface of the insert (4) are made to overlap concavities and convexities of the mating surface of the insert (5). As a result, one section of each of the inserts (4, 5) overlaps the other in the thickness direction, and the length to which the insert part (3) protrudes can thereby be shortened.
Patent CA-2985083-A1 (CA)
Title: Nanoparticules extremement petites, et procedes de fabrication et methodes d'utilisation correspondants
Inventor: WIESNER ULRICH B
IPC: A61K47/10
Filed: 2016-05-04
Abstract: L'invention concerne une méthodologie de synthèse aqueuse permettant la préparation de nanoparticules de silice (SNPs, pour "silica nanoparticles"), les SNPs noyau-enveloppe ayant par exemple une taille comprise entre 2 et 15 nm et une dispersion de taille étroite avec un contrôle de la taille en dessous de 1 nm, c'est-à-dire au niveau d'une couche atomique unique. Différents types de marqueurs, y compris des émetteurs dans le proche infrarouge (NIR, pour "near infrared"), peuvent être encapsulés à l'intérieur de manière covalente, et l'intensité de rayonnement peut être améliorée par le biais d'un ajout d'enveloppes de silice supplémentaires. La surface peut être fonctionnalisée avec du polyéthylène glycol (PEG) et, éventuellement, des ligands de surface spécifiques. Cette méthodologie de synthèse aqueuse permet également la synthèse de nanoparticules d'aluminosilicate (ASNPs, pour "aluminosilicate nanoparticles") fluorescentes de type noyau et noyau-enveloppe de taille comprise entre 2 et 15 nm, qui peuvent également être fonctionnalisées en surface. L'efficacité d'encapsulation et l'intensité lumineuse des fluorophores NIR fortement chargés négativement est améliorée par rapport aux SNPs correspondantes sans aluminium.
Patent CA-2985125-A1 (CA)
Title: Agents de liaison bispecifique a l'antigene membranaire specifique de la prostate (psma) et utilisations de ceux-ci
Inventor: ANDERSON GLENN
IPC: C07K16/00
Filed: 2016-05-06
Abstract: L'invention concerne des molécules de liaison à l'antigène bispécifiques de CD3 x PSMA ou un fragment de liaison à l'antigène bispécifique de celles-ci, un domaine FN3 se liant spécifiquement à l'antigène membranaire spécifique de la prostate humaine (PSMA) et un second site de liaison à l'antigène se liant de manière immunospécifique à CD3. L'invention concerne également des protéines de fusion et des polynucléotides apparentés capables de coder pour les protéines de fusion proposées et des cellules exprimant les protéines de fusion proposées. En outre, l'invention concerne des procédés d'utilisation des molécules de liaison à l'antigène bispécifiques de CD3 x PSMA ou un fragment de liaison à l'antigène bispécifique de celles-ci.
Patent CA-2986254-A1 (CA)
Inventor: BAEUERLE PATRICK
IPC: C07K19/00
Filed: 2016-05-18
Abstract: Provided herein are T-cell receptor (TCR) fusion proteins (TFPs), T-cells engineered to express one or more TFPs, and methods of use thereof for the treatment of diseases, including cancer.
Patent CA-2987277-A1 (CA)
Title: Fracturing utilizing an air/fuel mixture
Inventor: WILSON EDWIN E
IPC: C09K8/62
Filed: 2016-06-16
Abstract: A method of producing subterranean fractures in geologic formations for the extraction of hydrocarbons includes flowing an air and fuel mixture into a well hole. The well hole may then be sealed with a packer plug creating a compression chamber with the air and fuel mixture. A liquid, such as water, may be pumped into the well hole to create pressure in the compression chamber. The build-up of pressure eventually causes auto-ignition of the air and fuel mixture which fractures the formation. The water may then rush into the compression chamber which thermally shocks the area causing additional fractures. The water may vaporize to steam and thoroughly disinfect the well hole eliminating the need for added biocides.
Patent CA-2997051-A1 (CA)
Title: Novel pyrazolo[3,4-d]pyrimidine compound or salt thereof
Inventor: KAWAI YUICHI
IPC: A61K31/519
Filed: 2016-08-31
Abstract: Provided is a novel compound having an HER2 inhibitory action and a suppressive effect on cell proliferation. Also provided is a pharmaceutical useful in diseases involving HER2, especially in the prevention and/or treatment of cancer, on the basis of the HER2 inhibitory action. A compound represented by formula (I) [in the formula, X, Y, Z1, Z2, Z3, Z4, W, n, R1, R2, and R3 have meanings as defined in the specification] or a salt thereof.
Patent CA-2997163-A1 (CA)
Inventor: MACDONALD DANIEL N
IPC: C02F1/00
Filed: 2018-03-02
Abstract: An apparatus for filtering water includes a tubular housing defining a housing interior for holding a filter cartridge that radially divides the housing interior into a feed zone and a filtrate zone. The housing interior extends vertically from a bottom end to an upper end defining an upper end opening that is sized to allow the filter cartridge to be inserted into and removed from the housing interior. A lid is removably attached in sealing relationship to the housing top end to prevent water flow out of the housing interior via the housing top end opening. A distributor, attached in sealing relationship to the housing bottom end, has an inflow passage for directing water flow into the feed zone of the housing interior, and an outflow passage for directing water flow out of the filtrate zone of the housing interior, and into a tank storing a granular filtration medium.
Patent CA-2999983-A1 (CA)
Inventor: BAUER LORENZ J
IPC: B01J21/14
Filed: 2016-09-23
Abstract: Biomass is converted into a bio-oil containing stream in a riser reactor having multiple ports for the entry of fresh catalyst. Hard coke formed during pyrolysis may be separated from the riser effluent fraction containing which contains spent catalyst, soft coke and char. The separated hard coke may then be fed back into the riser reactor. The riser reactor may further have a cooling media which quenches the rapid heat transfer to the biomass during pyrolysis of the biomass in the mixing zone of the riser.
Patent CA-3004262-A1 (CA)
Title: Autonomous visual navigation
Inventor: WIERZYNSKI CASIMIR MATTHEW
IPC: G05D1/02
Filed: 2016-10-27
Abstract: A method of visual navigation for a robot includes integrating a depth map with localization information to generate a three-dimensional (3D) map. The method also includes motion planning based on the 3D map, the localization information, and/or a user input. The motion planning overrides the user input when a trajectory and/or a velocity, received via the user input, is predicted to cause a collision.
Patent CA-3005835-A1 (CA)
Title: Compositions contenant des acides amines non naturels et des polypeptides, procedes impliquant ces acides amines non naturels et polypeptides, et utilisations desdits acides amines non naturels et polypeptides
Inventor: MIAO ZHENWEI
IPC: C07C251/86
Filed: 2005-12-21
Abstract: Il est décrit des composés ou des sels de ceux-ci comprenant la Formule (XI) : (voir la Formule XI. Les composés décrits peuvent servir à produire des polypeptides ayant des acides aminés non naturels de la Formule (XI).
Patent CA-3009013-A1 (CA)
Inventor: JALBERT STEVE
IPC: B29C48/92
Filed: 2018-06-20
Abstract: Un procédé et un système permettant de créer des effets de couleur à laide dun matériau extrudable, tel que le plastique et le métal, sont présentés pour une utilisation dans notamment, des kayaks, des planches à pagaie et des meubles de jardin. La description de la circulation dun premier et dun second matériau visqueux de couleurs respectives est fournie. Ils sont ensuite combinés selon un modèle prédéterminé pour former un flux de matériau visqueux combiné. Un mélangeur dynamique est ensuite utilisé pour appliquer un mouvement prédéterminé de division, de renversement et de combinaison au flux de matériau visqueux combiné pour mélanger partiellement les premier et second matériaux visqueux. Le mélangeur dynamique peut être configuré pour obtenir une orientation radiale précise qui peut être modifiée au moins en partie en effectuant des rotations dans le sens des aiguilles dune montre et dans le sens inverse des aiguilles dune montre des éléments du mélangeur dynamique pendant lapplication du mouvement de division, de renversement et de combinaison provoquant des variations du motif de couleur dans le flux de matériau visqueux combiné.