baber/WOPTO huggingface dataset:
Patent EA-003558-B1 (EA)
Title: Purification of carboxaldehyde
Inventor: BERGLUND RICHARD ALAIN
IPC: C07C47/55
Filed: 1999-03-15
Abstract: 1. A method, which comprises reacting 4'-chloro-4- biphenylcarboxaldehyde with sodium bisulfite to obtain the bisulfite adduct, being conducted in an aqueous/acetonitrile solution having an acetonitrile concentration sufficient to cause the bisulfite adduct to precipitate. 2. The method of Claim 1 wherein the ratio of acetonitrile to water is from about 2: 1 to about 13: 1. 3. A process for preparing 4'-chloro-4- biphenylcarboxaldehyde bisulfite adduct which comprises: (1) reacting 4'-chloro-4-biphenylcarboxaldehyde with sodium bisulfite in an aqueous/acetonitrile solution having an acetonitrile concentration sufficient to cause the bisulfite adduct to precipitate, (2) isolating the bisulfite adduct precipitate from the solution, (3) mixing the isolated bisulfite adduct in an aqueous/acetonitrile solution having a water concentration sufficient to cause the regenerated aldehyde to precipitate, and (4) converting the bisulfite adduct to 4'chloro-4-biphenylcarboxaldehyde. 4. The method of Claim 3 wherein the bisulfite adduct is isolated from the solution and mixed in an aqueous/acetonitrile solution having a water concentration sufficient to cause the regenerated aldehyde to precipitate. 5. The method of Claim 3 wherein the ratio of acetonitrile to water is from about 1: 3 to about 1: 5 acetonitrile to water. 6. The method of Claim 3 wherein the pH of the solution on step (3) is from about 12 to about 14. 7. The method of Claim 6 wherein the pH of the solution on step (3) is from about 10 to about 14. 8. A process for preparing 4'-chloro-4-biphenylcarboxaldehyde bisulfite adduct which comprises: (1) reacting 4'-chloro-4-biphenylcarboxaldehyde with sodium bisulfite in an aqueous/acetonitrile solution having an acetonitrile concentration sufficient to cause the bisulfite adduct to precipitate, (2) isolating the bisulfite adduct precipitate from the solution, (3) mixing the isolated bisulfite adduct in an aqueous/acetonitrile solution having a water concentration sufficient to cause the regenerated aldehyde to precipitate, and (4) converting the bisulfite adduct to 4'chloro-4-biphenylcarboxaldehyde. 9. The method of Claim 1 wherein the ratio of acetonitrile to water is from about 2:1 to about 13:1. 10. A compound of the formula:
Patent EA-005662-B1 (EA)
Title: Atrial sensing and multiple site stimulation as intervention for atrial fibrillation
Inventor: MOWER M D MORTON M
IPC: A61N1/36
Filed: 2000-01-11
Abstract: Atrial sensing and stimulation as intervention for atrial fibrillation. The present invention relates to a method of atrial defibrillation. In a variety of protocols varying combinations of conventional and biphasic stimulation are applied at threshold and subthreshold levels. In a preferred embodiment, the implantable electronic stimulation device of the present invention includes multiple electrodes having stimulating and sensing capabilities. The small size of these electrodes allows for intravenous insertion into the patient.
Patent EA-005971-B1 (EA)
Title: Dry powder inhaler
IPC: A61M15/00
Filed: 2002-09-25
Abstract: An inhalation device for the uptake of medicaments that are in the form of dry powder contained in the blisters of specially designed single dose blister strips. The device is comprised of a mouthpiece (A), a strip support surface area (B), and one or more storage areas (C). Furthermore, the single dose blister strip is described. It is comprised of two sheets (17, 20) that are fixed in such a manner so that when they get separated the powder becomes available for inhalation.
Patent EA-014690-B1 (EA)
Title: Process for preparing racemic alkyl-5-halogenopent-4-enecarboxylic acids or alkyl-5-halogenopent-4-enecarboxylic esters
Inventor: POJALIEV PETER
IPC: C07C51/09
Filed: 2006-07-03
Abstract: A process for preparing racemic alkyl-5-halogenopent-4-enecarboxylic acids and esters thereof of the general formula (I)in which R is a C-C-alkyl radical, Ris H or C--alkyl and X is chlorine, bromine or iodine, which comprises a) reacting a dialkyl(alkylmalonate) of the general formula (II)in which R is as defined above and Ris a C-C-alkyl radical, in the presence of a metal alkoxide of the general formula MOR, in which M may be Na, K or Li, and Ris a C-C-alkyl radical, and in an organic solvent, with 1,3-dihalogenopropene to obtain the corresponding allylated malonate, then b) after full conversion, adding an inorganic salt and a C-Calcohol to the reaction mixture, heating the reaction mixture to the boiling temperature, then c) isolating the desired racemic ester of the general formula (I) from the reaction mixture by extraction or direct distillation and d) if the racemic acid is the desired end product, hydrolyzing the ester function.
Patent EA-016720-B1 (EA)
Title: Heterocyclic receptor agonists (variants), pharmaceutical composition based thereon, method for the treatment of diabetes and metabolic disorders, method for stimulating insulin secretion (variants) and methods of lowering glucose and triglyceride level in blood by using said compounds
Inventor: CHEN XIN
IPC: A01N43/40
Filed: 2007-12-27
Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
Patent EA-017101-B1 (EA)
Title: Filtration cell and filtration device using such cell
Inventor: KUROWSKI SERGE
IPC: B01D33/19
Filed: 2008-03-06
Abstract: The invention relates to a filtration cell that comprises a tank with a bottom wall (2) and four side walls extending upwards from the bottom wall as well as an upward opening, the four side walls including two opposite longitudinal walls (3, 5) as well as a front facing wall (4) and a rear facing wall connecting them, a filtration bed (7) supported in the tank, an outlet opening for discharging the filtrate, and a covering flap (24) protruding outwards from the top of one of said longitudinal walls, the longitudinal wall (5) opposed to that fitted with the flap including a lower portion (25) extending upwards from the bottom wall (2) and an upper portion (26) extending slantedly upwards and inside the tank from the top of said lower portion (25), and/or the front facing wall (4) comprises a bottom portion (27) extending upwards from the bottom wall (2) and a top portion (28); extending slantedly upwards and inside the tank from the top of said bottom portion (27).
Patent EA-016682-B1 (EA)
Title: Fermenter for generating biogas from pumpable organic material
Inventor: GANTEFORT WILHELM
IPC: B01J8/02
Filed: 2008-05-16
Abstract: The invention relates to a fermenter for generating biogas from pumpable organic material with a low content of organic dry matter (oTS), comprising at least one inlet for the pumpable organic material, at least one fixed bed reactor for the pumpable organic material with at least one primary and one secondary section and at least one outlet the remaining fermentation residue. Furthermore, the fermenter can optionally comprises at least one sedimentation chamber for the pumpable organic material, arranged between the primary and secondary sections and at least one recycling section connected to the sedimentation chamber and designed such that specific lighter fractions of the pumpable organic material can be recovered and reintroduced to the rising (primary) section of the fixed bed reactor or a preceding or subsequent conventional fermenter.
Patent EA-019285-B1 (EA)
Title: Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
Inventor: ALBERT MARTIN
IPC: C07C205/51
Filed: 2009-05-19
Abstract: The present invention relates to processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid ester and its salts. Also disclosed are processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid salt and a process for the preparation of 3-(aminomethyl)-5-methylhexanoic acid. (S)-5-Methyl-3-nitromethyl-hexanoic acid or (R)-5-methyl-3-nitromethyl-hexanoic acid in enantioenriched form or enantiopure form as well as salts thereof, (S)-5-methyl-3-nitromethyl-hexanoic acid ester or (R)-5-methyl-3-nitromethyl-hexanoic acid ester in enantioenriched form or enantiopure form and a compound, namely Formula (XIII), in racemic form, enantioenriched form or enantiopure form are also disclosed.
Patent EA-018001-B1 (EA)
Title: 3-indazolyl-4-pyridylisothiazoles
Inventor: BRITTON THOMAS CHARLES
IPC: A61K31/4439
Filed: 2009-03-18
Abstract: The present invention provides 3-indazoyl-4-pyridylisotbiazoles of the following formula or pharmaceutically acceptable salts thereof, representing selective receptors (mGluR) antagonists, pharmaceutical compositions based thereon and methods for use thereof in the treatment of anxiety.
Patent EA-022538-B1 (EA)
Title: Coating for a device for shaping glass material
Inventor: BILLIERES DOMINIQUE
IPC: C23C30/00
Filed: 2009-11-30
Abstract: The invention relates to a coating for a device for shaping glass materials, including a first quasicrystalline, approximate, or amorphous metal phase and a second phase consisting of a eutectic alloy having a fusion point of 950 to 1,150°C and a nominal hardness of 30 to 65 HRC; equipment for shaping glass into sheet glass or plate glass provided with said coating; a material consisting of said coating; a premixed or prealloyed powder, or a formed flexible cord or wire, making it possible to obtain said coating; and a thermal projection method for obtaining said coating.
Patent EA-021165-B1 (EA)
Title: Hoisting machine
Inventor: KOVALEV VALERIJ ALEKSANDROVICH
IPC: B66F19/00
Filed: 2012-06-04
Abstract: The invention relates to handling machinery used for lifting/lowering cargoes by different vehicles, at storehouses and industrial rooms. The aim of the invention is to develop a compact structure of a handling mechanism. The technical result is faster mounting and cargo handling. Hoisting machine comprises a foundation with a hollow horizontal rod accommodating a pusher with rollers and pivotally coupled with its drive composed of a hydraulic cylinder. The horizontal hollow rod has an opening to receive a thrust equipped with a working platform for cargo gripping and a link, one end of which is articulated with the pusher while the opposite end is hinged to aforesaid thrust to displace in a vertical plane. Thrust vertical drive is secured under the thrust, at foundation, and composed by a telescopic boom, its top telescoping section being equipped with a thrust support. Thrust is fitted into the foundation to displace horizontally.
Patent EA-026569-B1 (EA)
Title: Processes for preparing certain pyrimidine compounds and intermediates thereof
Inventor: CARDWELL KEVIN STUART
IPC: C07D239/70
Filed: 2011-05-17
Abstract: This invention relates to processes for preparing a compound of formula (I) and intermediates thereof. The compounds of formula (I) are useful for treating cardiovascular and inflammatory diseases such as atherosclerosis.
Patent EA-036213-B1 (EA)
Title: Controlled release peptide formulations
Inventor: TIBERG FREDRIK
IPC: A61K47/14
Filed: 2012-05-25
Abstract: The present invention relates to pre-formulations forming a low viscosity mixture of: (a) 33-60 wt.% of at least one diacyl glycerol and/or a tocopherol; (b) 33-55 wt.% of at least one phosphatidyl choline (PC); (c) 0.1-20 wt.% of at least one biocompatible, organic mono-alcoholic solvent; (d) from 1.2 to 20 wt.% of a polar solvent; (e) at least one peptide active agent different from glucagon-like peptide (GLP-1); wherein the pre-formulation has a viscosity 1-1000 mPas at 20°C; wherein the ratio of components (a):(b) is in the range 40:60 to 54:46; wherein the pre-formulation is capable of forming at least one liquid crystalline phase structure upon contact with excess aqueous fluid. The invention further relates to the manufacture of such formulations, to methods of treatment comprising administration of such formulations, and to pre-filled devices containing such formulations.
Patent EA-027360-B1 (EA)
Title: Schottky diode manufacturing method
Inventor: TURTSEVICH ARKADY STEPANOVICH
IPC: H01L29/872
Filed: 2014-09-23
Abstract: The invention is related to semiconductor devices manufacturing processes, in particular, to a method for manufacturing powerful Schottky diode chips that can be used, e.g., as AC rectifiers in power electronics devices. The objective of the invention is reduction of specific consumption of platinum without an increase in reverse current level. The essence of the invention is that in a Schottky diode manufacturing method comprising formation of a Schottky electrode by application of nickel-platinum-vanadium alloy film to an oxidized heavily doped silicon substrate of a first conductivity type with a lightly doped epitaxial layer of the same conductivity type and a guard ring of a second conductivity type formed in the epitaxial layer, with a contact window opened in silicon oxide, heat treatment in an inert or reducing environment at a temperature of 200 to 450°C during a time interval of 60 to 300 min, heat treatment in an inert or reducing environment at a temperature of 525 to 575°C during a time interval of 15 to 60 min, removal of unreacted residues of nickel-platinum-vanadium alloy, formation of anode metallization by successive application of layers of vanadium, aluminium or aluminium alloys, nickel and silver followed by photolitography, creation of cathode metallization by successive application of layers of titanium, nickel and silver, the nickel-platinum-vanadium alloy film having a thickness of 10 to 20 nm.
Patent EA-025388-B1 (EA)
Title: Infusible beverage ingredient and process for the manufacture thereof
Inventor: BEINDORFF CHRISTIAAN MICHAEL
IPC: A23L27/12
Filed: 2012-08-21
Abstract: The present invention relates to a process for the manufacture of an infusible beverage ingredient comprising dried fruit pieces, the process comprising the steps of: (a) providing fruit pieces and coating particles; (b) mixing the fruit pieces and the coating particles to provide coated fruit pieces; and then (c) drying the coated fruit pieces to a moisture content of less than 30 wt.%, preferably to a moisture content of 0.1 to 10 wt.% wherein the coating particles comprise particles of fruit peel which are less than 1.5 mm in diameter.
Patent EA-027131-B1 (EA)
Title: Pump unit
Inventor: LARSEN ANDREAS BOERRE
IPC: F04B17/03
Filed: 2009-12-08
Abstract: The invention discloses a pump unit (101) comprising two driving devices (103), each of which is separately connected to two pumps (105) or compressors and which are adapted to provide variable pressure in chambers of said pumps (27") (105) or compressors by means of reciprocate motion of a rod (23) in each driving device. The rods (23) are fixed in casings of the driving devices movably to perform reciprocate motion, and each driving device (103) further comprises an electric motor (31) adapted to provide reciprocate motion of the rod (23). The electric motor is a permanent-magnet rotor motor, the rods pass through the rotor (31b) of the respective motor (31), and a rotary-to-linear motion conversion means (33) is functionally connected between the rod and the motor rotor to provide conversion of rotary motion of the rotor to rectilinear motion of the rod. Each rod is linked to a pair of pistons or plungers providing said variable pressure. Said four pumps or compressors are, respectively, pumps or compressors designed for pumping or compressing a fluid when actuated by said variable pressure. Said two rods of said two driving devices are adapted to move with a phase shift of 90° and to perform continuous reciprocate motion.
Patent EA-029643-B1 (EA)
Title: Co-micronisation product comprising a selective progesterone-receptor modulator, method for preparing same and pharmaceutical composition based thereon
Inventor: BATTUNG FLORIAN
IPC: A61P15/18
Filed: 2013-11-07
Abstract: The object of the present invention is a co-micronisation product for preparing a pharmaceutical composition comprising an active principle selected from the group consisting of selective progesterone-receptor modulators of formula (Ia)wherein Rrepresents -OH, a C-Calkoxy group or -C(O)-R; Rrepresents -OH, a C-Calkoxy group, a C-Calkynyl, a C-Calkenyl or -OC(O)-R, where Rand Rare independently selected from a C-Calkyl group and a C-Calkoxy group; Rrepresents -NRR, where Rand Rare independently -H or C-Calkyl; -CH=N-O-R, where Ris -H or -C(O)-X-R, where Ris C-Calkyl, and X represents O, NH or S; or -C(O)R, where Ris C-Calkyl; and an N-vinyl-2-pyrrolidone-based polymer vehicle. The invention also relates to a pharmaceutical composition comprising said co-micronisation product and to the therapeutic use thereof.
Patent EA-028581-B1 (EA)
Title: DIHYDROPYRIDONE P1 AS FACTOR XIa INHIBITORS
Inventor: YANG WU
IPC: C07D487/18
Filed: 2013-08-02
Abstract: The present invention relates to compounds of Formula (V)or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
Patent EA-032354-B1 (EA)
Title: Method for manufacturing a sealing device protected against substitution or forgery, and sealing device with a protective label
Inventor: LIKHACHEV SERGEY VIKTOROVICH
IPC: G09F3/03
Filed: 2016-07-13
Abstract: The invention is related to a method for protection of plastic sealing devices and sealing devices with an outside plastic shell against substitution or forgery, and to a sealing device with a protective label designed to indicate facts of unauthorized access to protected items. The essence of the proposed inventions consists in forming a protective label on the sealing device, in the area allotted for application of identification information. The protective label has preset, distinct boundaries separating the label from the base material (shell) of the sealing device, and differs from it in colour, texture, shape, depth or other properties of polymer material. Any substitution or forgery of the sealing device is detected by the absence or distortion of the preset features including features of marking display on the protective label which are specific to the previously installed (original) sealing device. The technical result is higher reliability of sealing device protection against substitution and forgery, enhanced responsiveness to determine their authenticity (originality) in visual way, without the use of special equipment.
Patent EA-037795-B1 (EA)
Title: Aircraft with vertical takeoff and landing and method of operating same
Inventor: RAZVAN SABIE
IPC: B64C39/00
Filed: 2016-12-16
Abstract: The invention relates to an aircraft of aerodyne type with vertical takeoff and landing and a method of operating the same. The aircraft comprises a circular symmetrical bearing aerodynamic body (1) having an internal stiffening platform (2) located on the chord of the aerodynamic profile, at least four vertical intubated propellers (3a), (3b), (3c), (3d) arranged symmetrically to the central vertical axis of the bearing body (1), to the predetermined flight axis and to the transverse axis of the bearing body (1), the propellers (3a) and (3c) having the same rotation direction opposite to that of the propellers (3b) and (3d), at least two horizontal intubated propellers (4) with opposite rotation directions placed parallel symmetrical to the flight axis and on both sides of it, wherein the horizontal and vertical intubated propellers are bidirectional and may rotate in both directions, vector nozzles (5), a means of power supply (6), an electronic flight control and management module (7) and a landing gear (9), wherein the aircraft may be driven by a pilot on board the aircraft or by a pilot seated on the ground by means of a radio remote control (10).
Patent EA-035636-B1 (EA)
Title: Device for control of geometric parameters of a product surface
Inventor: PESTEREV SERGEY NIKOLAEVICH
IPC: G01B11/24
Filed: 2018-07-24
Abstract: This invention relates to control and measuring equipment, namely, to automated non-contact measuring machines for monitoring of geometrical parameters of surface profile, in particular, threads of pipes, lock couplings and similar articles including thread. The device for monitoring the geometric parameters of the surface of a product contains an optical meter (1) mounted on a carbon fiber console (23), a mechanical movable module, a control unit (5). The mechanical movable module comprises a frame (16), a vertical displacement unit (17), a platform (18) and an eccentricity unit (19) on which a carbon fiber console is installed (23). The latter is equipped with a micromotor assembly (24) of the optical meter (1). The control unit (5) is configured to synchronize the output signals and the spatial position of the optical meter (1), and is able to exchange data with an external computer unit (6). The technical result consists in the compensation of errors arising due to operating conditions when measuring the geometric parameters of the surface of a product and product design features.
Patent EA-036987-B1 (EA)
Title: Systems and methods for device authentication
Inventor: Ellingson John
IPC: H04W12/04
Filed: 2017-09-08
Abstract: Embodiments include methods, and systems and computing devices configured to implement the methods of authenticating a computing device. A processor of a first computing device may obtain a transitory identity and may send the transitory identity to a second computing device and a third computing device. A processor of the second computing device may send the transitory identity to the third computing device with a request to authenticate the first computing device. The processor of the third computing device may authenticate the identity of the first computing device in response to determining that the transitory identity received from the first computing device matches the transitory identity received from the second computing device.
Patent EA-037054-B1 (EA)
Title: Pyrolysis gasifier comprising automatic ash processor
Inventor: LIM YUNG TAEK
IPC: C10J3/84
Filed: 2018-01-02
Abstract: An embodiment of the present invention may provide a pyrolysis gasifier comprising a tubular body configured to receive and pyrolyze a combustible waste; a bottom door disposed below the tubular body to selectively seal the tubular body; a main frame supporting the tubular body; a base frame supporting the bottom door; an automatic ash processor configured to, while traveling in one direction, push and remove ash remaining on the bottom door after pyrolysis of the combustible waste; and a guide frame supporting the automatic ash processor and configured to guide the travel of the automatic ash processor.