baber/WOPTO huggingface dataset:
Patent NZ-705676-A (NZ)
Title: Process for the preparation of 2-amino-5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidine from 4-chloro-2,5-dimethoxypyrimidine
Inventor: ROTH GARY
IPC: C07D487/00
Filed: 2013-09-10
Abstract: 2-Amino-5,8-dialkoxy[1,2,4]-triazolo[1,5-c]pyrimidines are manufactured from 4-chloro-2,5-dialkoxypyrimidines in a process that avoids hydrazine and cyanogen halide.
Patent NZ-709790-A (NZ)
Title: Method for improving the dissolution profile of a biologically active material
Inventor: MEISER FELIX
IPC: B01J2/00
Filed: 2010-04-23
Abstract: The present disclosure relates to a method for producing a composition comprising a biologically active material with an improved dissolution profile, said method comprising the steps of: dry milling a solid biologically active material, a milling aid and a millable grinding matrix in a mill, for a time period sufficient to produce particles of the biologically active material dispersed in an at least partially milled grinding matrix, wherein the particles have an average particle size falling within the range of 1– 200 µm determined on a particle number basis, wherein the average particle size of the biologically active material is reduced by less than 70% during dry milling, wherein the dissolution of the biologically active material is improved such that a dissolution concentration of X is achieved in 10-30 minutes and X is the concentration equal to the dissolution concentration of the biologically active material prior to dry milling after 60 minutes, wherein the particle size of the millable grinding matrix is reduced by the dry milling, wherein the time period sufficient is a range selected between 5 minutes and 8 hours. Also disclosed is the composition and unit dosage made by the method.
Patent NZ-712279-A (NZ)
Title: Hair increasing tool and method for attaching the same
Inventor: TOBA MAYUMI
IPC: A41G5/00
Filed: 2014-03-03
Abstract: In a hair increasing tool, two large-diameter portions 11, 12 are provided on a line-member 10 having a predetermined length with a certain distance. A line member portion between said two large-diameter portions 11, 12 is defined as a plant-area 15. Line-member portions located outside said large-diameter portions are defined as assist-areas 16, 17. First false hairs 20 are fixed to a plurality of positions of said plant-area 15 with predetermined interval(s). Tube-members 18, 19 which can be plastically deformed are fixed to a location near said large-diameter portions 11, 12 on the line-member 10. Assist-areas 16, 17, to which no false hair is fixed, are configured to (i) be grasped by an operator or a user when the hair increasing tool is fixed to a head of the user, and (ii) be cut away after the hair increasing tool is fixed to the head of the user. The tube-members 18, 19 are collapsed with remaining own hairs inserted therein, thereby fixing the tube-members 18, 19 to the own hairs. The line-member portion which defines the plant-area 15 is placed along a surface of the head of the user, and the line-member portion is fixed by knotting the own hairs located at both sides of the line-member portion together to fix said line-member portion at a plurality of positions, thereby pinching said line-member portion by the own hairs. Accordingly, the hair increasing tool can be fixed to the head with sufficient strength and stability without using adhesive agent.
Patent NZ-716717-A (NZ)
Title: An expression construct and process for enhancing the carbon, nitrogen, biomass and yield of plants
Inventor: KAACHRA ANISH
IPC: C12N15/82
Filed: 2012-04-19
Abstract: Disclosed is an expression construct comprising SEQ ID NO. 7 for co-expression of the genes AspAT, GS and PEPCase comprising nucleotide sequences SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3, linked to at least one control sequence and a transcription terminator sequence, useful for enhancing the carbon, nitrogen, biomass and yield of plants as compared to wild type or untransformed plant.
Patent NZ-725487-A (NZ)
Title: Combination of lenalidomide or pomalidomide and cd38 antibody-attenuated interferon-alpha constructs, and the use thereof
Inventor: POGUE SARAH
IPC: C07K16/46
Filed: 2015-05-01
Abstract: Methods for cancer treatment include administering to a cancer patient an anti- CD38 antibody-attenuated human IFN alpha-2b construct and lenalidomide or pomalidomide. Tumors that may be treated according to these methods include tumors which comprise CD-38 expressing tumor cells, including B-cell lymphoma, multiple myeloma, non-Hodgkin’s lymphoma, chronic myelogenous leukemia, chronic lymphocytic leukemia, and acute lymphocytic leukemia.
Patent NZ-727129-A (NZ)
Title: Immuno-modulatory progenitor (imp) cell
Inventor: REGINALD AJAN
IPC: C12N5/078
Filed: 2015-06-09
Abstract: The invention relates to immuno-modulatory progenitor (IMP) cells and their use in therapy. A population of IMP cells derived from bone marrow mononuclear cells that express on their surfaces detectable levels of MIC A/B, CD304, CD178, CD289, CD363, CD99,CD181,EFG-R, CXCR2 and secrete IL-6 and IL-8. Wherein the cells are produced using by (i) culturing mononuclear cells (MCs) for from 15 to 25 days in a medium comprising platelet lysate, at less than 20% oxygen (O2) and under conditions which allow the MCs to adhere to induce the MCs to differentiate into IMP cells and (ii) harvesting and culturing those IMP cells which have an expression pattern as defined in claim 1 and thereby producing a population according to claim 1, wherein the platelet lysate is produced by subjecting a population of human platelets to four freeze-thaw cycles, wherein the freeze portion of each cycle is carried out in liquid nitrogen.
Patent NZ-728018-A (NZ)
Title: Thioureylene liquid compositions
Inventor: REYNOLDS LOUISE
IPC: A61K9/08
Filed: 2015-06-23
Abstract: The present invention relates to novel liquid compositions and formulations containing a thioureylene compound, a polysaccharide and a liquid vehicle. The compositions and formulations of the invention are useful for dealing with diseases and conditions associated with abnormally high thyroid hormone levels in mammals,such as humans and cats.
Patent NZ-730940-A (NZ)
Title: Crystalline forms of 5-chloro-n4-[-2-(dimethylphosphoryl) phenyl]-n2-{ 2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] pyrimidine-2,4-diamine
Inventor: SHARMA PRADEEP
IPC: C07D239/48
Filed: 2015-10-21
Abstract: Crystalline forms of brigatinib, pharmaceutical compositions comprising the same, and methods of their preparation and use of the same are disclosed herein.
Patent NZ-732793-A (NZ)
Title: Formulations of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methycyclohexylamino)-pyrimidine-5-carboxamide
Inventor: ZOU DAOZHONG
IPC: A61K31/505
Filed: 2015-12-15
Abstract: Provided are pharmaceutical compositions and dosage forms of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide, or a pharmaceutically acceptable stereoisomer, tautomer, solid form, polymorph, salt, hydrate, clathrate, or solvate thereof. Also provided are methods of treating, managing, or preventing various disorders, such as diseases or disorders treatable or preventable by inhibition of a JNK pathway in mammals using such pharmaceutical compositions or dosage forms. Further provided are salts of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)- pyrimidine-5-carboxamide and methods of preparation of such salts.
Patent NZ-737298-A (NZ)
Title: Privacy enhanced personal search index
Inventor: LEE HO JOHN
IPC: G06F21/62
Filed: 2016-06-24
Abstract: Examples of the present disclosure describe systems and methods for enhancing the privacy of a personal search index. In some aspects, a personal clear text document may be used to generate an encrypted document digest and an encrypted document on a first device. A second device may decrypt the document digest, build a personal search index based on the decrypted document digest, and store the encrypted document in a data store. The first device may subsequently receive a clear text search query that is used to query the personal search index on the second device for encrypted documents.
Patent NZ-741612-A (NZ)
Title: Natural killer cells and ilc3 cells and uses thereof
Inventor: HARIRI ROBERT
IPC: A61P35/00
Filed: 2016-10-14
Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors, specifically SR-1 and CH223191. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.
Patent NZ-743815-A (NZ)
Title: Tetravalent anti-psgl-1 antibodies and uses thereof
Inventor: LIN SHIH-YAO
IPC: C07K16/18
Filed: 2017-01-06
Abstract: Provided herein are tetravalent antibodies that specifically bind to human PSGL-1. Unlike bivalent antibodies, these tetravalent antibodies contain a dimer of two monomers, with each monomer comprising two light chain variable (VL) domains and two heavy chain variable (VH) domains. This format allows for cross-linker/FcR-expressing cell-independent tetravalent antibodies against PSGL-1 that show enhanced efficacy as compared to bivalent PSGL-1 antibodies. These tetravalent antibodies can be used in a variety of diagnostic and therapeutic methods, including without limitation treating T-cell mediated inflammatory diseases, transplantations, and transfusions.
Patent NZ-754947-A (NZ)
Title: Composition of mannuronic diacid
Inventor: XIAO ZHONGPING
IPC: A61P25/28
Filed: 2017-12-27
Abstract: A mannuronic dicarboxylic acid oligosaccharide composition, which comprises mannuronic dicarboxylic acid of formula (III) or a pharmaceutically acceptable salt thereof, where n is an integer selected from 1-9, M is selected from 0, 1, or 2, m’ is selected from 0 or 1, the total weight of mannuronic dicarboxylic acid for which n = 1-5 accounts for 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic dicarboxylic acid for which n = 1-3 to the total weight of mannuronic dicarboxylic acid for which N = 4-7 is between 1.0 and 3.5.
Patent NZ-772991-A (NZ)
Title: Techniques for search space management
Inventor: LUO TAO
IPC: H04W52/02
Filed: 2019-09-16
Abstract: Methods, systems, and devices for using a common physical downlink control channel (PDCCH) to indicate transmission beams to be used by a base station during a transmission opportunity or a periodicity to monitor search spaces are described. A user equipment (UE) may monitor a search space (in some cases, using a periodicity) for the common PDCCH to determine if transmission beams associated with the UE are to be used during the transmission opportunity. If so, the UE may wake-up during at least a portion of the transmission opportunity to receive additional information. If the common PDCCH indicates that no transmission beams associated with the UE are to be used during the transmission opportunity, the UE may enter or re-enter the sleep state. The UE may switch to a new periodicity for monitoring the search space based on the information transmitted within the common PDCCH.
Patent PT-106746-A (PT)
Title: Painel laminado de material à base de cortiça dotado de um elemento de união em material à base de cortiça e desprovido de camadas de madeira
Inventor: CHAGAS JOSÉ ANTÓNIO MARCH O DAS
IPC: E04F15/00
Filed: 2013-01-22
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM PAINEL (1) LAMINADO DE MATERIAL DE CORTIÇA OU DE MATERIAL À BASE DE CORTIÇA, DESPROVIDO DE QUALQUER MATERIAL DE MADEIRA, COMPREENDENDO O PAINEL (1), PELO MENOS, UMA CAMADA (2) CENTRAL DE MATERIAL DE CORTIÇA OU DE MATERIAL À BASE DE CORTIÇA, POSSUINDO A CAMADA (2) CENTRAL UMA PRIMEIRA FACE E UMA SEGUNDA FACE; PELO MENOS, UMA CAMADA (4) EXTERIOR DE DESGASTE DISPOSTA NA REFERIDA PRIMEIRA FACE DA CAMADA (2) CENTRAL; E UM ELEMENTO (3) DE UNIÃO DISPOSTO EM, PELO MENOS, DOIS LADOS DO PAINEL (1), SENDO O ELEMENTO (3) DE UNIÃO UMA EXTENSÃO DA REFERIDA CAMADA (2) CENTRAL DE MATERIAL DE CORTIÇA OU À BASE DE CORTIÇA NESSES LADOS. O PAINEL PODE COMPREENDER AINDA UMA CAMADA (5) EXTERIOR DE BASE DISPOSTA NA SEGUNDA FACE DA CAMADA (2) CENTRAL. A INVENÇÃO DIRIGE-SE DE UM MODO GERAL À INDÚSTRIA DA CONSTRUÇÃO, EM PARTICULAR APLICA-SE A PAVIMENTOS.
Patent PT-106827-A (PT)
Title: Bioreator de estímulo para caracterização biomecânica de engenharia de tecidos
Inventor: COMPLETO ANTÓNIO MANUEL GODINHO
IPC: C12M1/34
Filed: 2013-03-11
Abstract: BIOREATOR PARA CARACTERIZAÇÃO BIOMECÂNICA DE CONSTRUÇÕES CELULARES BIDIMENSIONAIS E TRIDIMENSIONAIS DE ENGENHARIA DOS TECIDOS SEM INTERRUPÇÃO DO CRESCIMENTO CELULAR, PERMITINDO ESTABELECER UMA CORRELAÇÃO ENTRE PROPRIEDADES MECÂNICAS, NOMEADAMENTE MÓDULO DE ELASTICIDADE À COMPRESSÃO/TRAÇÃO, MÓDULO DE RIGIDEZ AO CORTE, MÓDULO À FLEXÃO E PERMEABILIDADE, E PARÂMETROS QUÍMICOS DO MEIO DE CULTURA, NOMEADAMENTE PH E TENSÃO DE OXIGÉNIO, E DIFERENTES REGIMES E MODOS DE ESTÍMULO MECÂNICO E/OU ESTÍMULO ELÉTRICO E/OU ESTÍMULO MAGNÉTICO, NOMEADAMENTE COMPRESSÃO/TRAÇÃO AXIAL, CORTE POR TORÇÃO, FLEXÃO, PERFUSÃO E COMPRESSÃO HIDROSTÁTICA, POR FORMA A DESENVOLVER UM TECIDO ARTIFICIAL PLENAMENTE FUNCIONAL PARA IMPLANTAÇÃO IN-VIVO. OS MODOS E TIPOS DE ESTIMULAÇÃO SÃO MODIFICADOS AUTONOMAMENTE EM FUNÇÃO DAS PROPRIEDADES BIOMECÂNICAS DAS CONSTRUÇÕES CELULARES E DOS PARÂMETROS QUÍMICOS DO MEIO DE CULTURA ATRAVÉS DE UMA OU MAIS FUNÇÕES OBJETIVO. BIOREATOR COMPREENDE UMA CÂMARA DE CULTURA ESTANQUE DESLIZANTE (3) QUE COMPREENDE GARRAS (34, 35, 22, 21) PARA FIXAÇÃO DAS CONSTRUÇÕES CELULARES (27, 20) LIGADAS À CÉLULA DE CARGA (14) E ATUADOR (4) E UM SISTEMA DE CONTROLO (7).
Patent RO-90956-A (RO)
Inventor: DEMARES HENRY M
IPC: C03B3/00
Filed: 1984-07-16
Abstract: Liquefying of pulverulent batch materials (e.g., glass batch) is carried out in two stages. The first stage (10) utilizes extended gas/solid contact to heat the materials to an intermediate temperature, and may recover waste heat. The second stage (12) rapidly liquefies the material in a cavity lined with the batch material, and may employ substantially nitrogen-free heat sources. Another aspect involves maintaining a wet condition in the first stage to entrap particulates.
Patent RU-94019986-A (RU)
Inventor: POUNUR KAVEKH
IPC: B01D25/133
Filed: 1992-10-03
Abstract: FIELD: microstructural, membranes. SUBSTANCE: microstructural membrane has sheet with two surfaces, matrix with holes running from one of the surfaces inside the sheet. Each hole of the matrix is encircled with flat zone and average typical sizes of holes amount to 0.1-5000.0 mcm. In this case, the hole size spread is less than 10% and their axes are parallel. Area of holes and hole spacing on the matrix are, as a whole, homogeneous on one of the surfaces, and sheet is made from glass, ceramics, metal, polymer or combinations of these materials. The method for manufacture of the microstructural membrane includes formation of the mask and matrix with holes in it. Mask is located in the immediate vicinity or in contact with one of the surfaces of the sheet of formed membrane. Holes are formed over the entire surface by directed action onto the mask of collimated flux of reactive ions or energy beam. Mask is formed in the close contact with the sheet of prepared membrane and the value of surface porosity on one of sheet surfaces amounts to, at least, 40%. EFFECT: higher efficiency. 26 cl, 6 dwg
Patent RU-94021004-A (RU)
Inventor: LOMACHINSKIJ V A
IPC: B01D11/02
Filed: 1994-05-24
Abstract: FIELD: wine making and juice industry. SUBSTANCE: installation has means to feed raw material and extractant, mixer connected to these means, and successively installed thereafter following equipment forming recycle circuit. Extractor made in the form of radio-transparent drum with openings in its side wall in the form of Lavale nozzles. Drum is enclosed by radio-transparent case and mounted on hollow horizontal drive shaft with openings to form annular chamber. The case holds microwave applicator. The drum is succeeded with separator, evaporator, condenser and collector tanks for groats and extract connected with separator and evaporator, respectively. Evaporator through its gas phase zone is additionally connected with annular chamber of extractor, and mixer is connected with the latter through hollow shaft. EFFECT: enhanced efficiency of operation. 3 cl, 3 dwg
Patent RU-94023807-A (RU)
Inventor: KLIMOVA N V
IPC: C07C49/493
Filed: 1994-06-23
Abstract: FIELD: medicine. SUBSTANCE: invention discloses new process for preparing 1-hydroxyadamantan-4- one (immune stimulating drug "kemantane" which is obtained by oxidizing adamantanone in the presence of catalysts with mixture of concentrated sulfuric and nitric acids. Catalysts include oxides of variable valency metals and alkali metal nitrites. Complex compounds formed in the reaction are decomposed by boiling in the presence of inert carriers. The claimed invention makes it possible to make the process more efficient and also increase the yield and improve quality of 1-hydroxyamantan-4-one. EFFECT: improved properties of the title compounds.
Patent RU-94025895-A (RU)
Inventor: VERPETA A S
IPC: H01H33/66
Filed: 1994-07-12
Abstract: FIELD: electrical engineering, in particular, high-voltage electric apparatuses, it is intended for switching and protection of load electric circuits. SUBSTANCE: the switch has a vacuum arc chute with break gap 16, contact spring 15, switching axle 1 with lever 2, which is connected to break gap 16 by means a free trip mechanism. The switch provides for disconnection of the power mechanism from the contact system for the period of disconnection operation, thus the speed of contacts break does not depend on the kinematics of the power mechanism and is determined by the spring characteristics only. EFFECT: enhanced reliability. 1 dwg
Patent RU-94029153-A (RU)
Title: Truck tipper
Inventor: SEMAKIN M S
IPC: B65G67/48
Filed: 1994-08-03
Abstract: FIELD: agricultural machinery; equipment for grain and vegetable stores. SUBSTANCE: truck tipper has two platforms installed on axles for turning in vertical plane. Rod of power cylinder is connected to lower side of one of platforms. Rod and piston spaces of power cylinder are connected by pipeline with control throttle valve. Cantilever portions of both platforms are interconnected by flexible tie which provides lifting of one platform in horizontal position when other platform is lowered. Axles of platforms are displaced from platform edges to side of unloading. Thanks to it one row of wheels can move from platform directly to ground. Second row of wheels moves along ramp and then also gets on ground. EFFECT: enlarged operating capabilities.
Patent RU-94030250-A (RU)
Inventor: IGNAT EV D M
IPC: B61H7/02
Filed: 1994-08-16
Abstract: FIELD: railway transport; brake systems. SUBSTANCE: brake shoe has metal frame and polymeric composite friction member made of two layers of different thermal conductivity. Layer in contact with metal frame is made of polymeric composite material whose conductivity is smaller than that of other layer which is arranged at side shoe working surface. EFFECT: increased service life of brake shoe, enhanced reliability. 1 cl
Patent RU-94042511-A (RU)
Inventor: VAJLER N I
IPC: C03B5/24
Filed: 1994-11-30
Abstract: FIELD: glass melting. SUBSTANCE: method includes measuring glass bath temperature, determining heat conductance and viscosity of bath using original appliance and affecting amount of heat coming into furnace in such a way as to maintain temperature, heat conductance, and viscosity of glass mass in the ranges set according to process requirements. EFFECT: facilitated process. 2 dwg
Patent RU-94046031-A (RU)
Inventor: SHVARTS DZHEFFRI
IPC: B01D53/86
Filed: 1994-11-15
Abstract: FIELD: chemical technology, ecology. SUBSTANCE: chlorine content in chlorinated hydrocarbons is decreased by contact of chlorinated hydrocarbon with dechlorinating reagent which consists of (i) complex of nontoxic metal exhibiting at least two oxidation states and (ii) reducing agent which reduces complex recovering its from the second oxidation state to the first one. Reagent example is a system: bis-(η-cyclopentadienyl)-titanium dichloride/sodium tetrahydroborate. EFFECT: improved method of chlorine content decrease.
Patent RU-95101186-A (RU)
Inventor: KOPYTIN E V
IPC: B67B7/16
Filed: 1995-01-26
Abstract: FIELD: medicine. SUBSTANCE: device has grip with handles. Grip is made in the form of semi-rings hinged to each other and provided with inner circumferential groove intended for gripping metal cap of vessel. Inner diameter of lower wall of groove is less than outer diameter of vessel cap and height of groove is less than height from upper plane of metal cap to lower wall of rubber plug shoulder. EFFECT: simple design, safe operation, possibility of repeated use of caps, convenience of operation. 6 dwg, 2 cl
Patent RU-95108349-A (RU)
Inventor: TOROPOV A S
IPC: B27B7/00
Filed: 1995-05-24
Abstract: FIELD: forest industry, in particular, production and cutting of timber material. SUBSTANCE: apparatus has guides for carriage 1, frame of carriage 2, frame movable in vertical plane over frame of carriage 3, frame for mounting saw 4 pivotally mounted on frame 3 with retainer 5, saw 6, drive 7, receiving device 8, pressure device 9. EFFECT: wider operational capabilities, simplified construction and enhanced reliability in operation. 2 cl, 4 dwg
Patent RU-95111039-A (RU)
Inventor: MEL NIKOV V G
IPC: C10M131/08
Filed: 1995-06-28
Abstract: FIELD: chemistry of polymers. SUBSTANCE: proposed lubricant composition has the following components, wt.-%: surface-active substance of the general formula (I) 0.01-3.0, and hydrocarbon oil - the rest. Proposed lubricant composition can be used in motor, transmission, industrial oils and others. EFFECT: enhanced quality of composition.