baber/WOPTO huggingface dataset:
Patent JP-2006169378-A (JP)
Title: Liquid agent for cleaning
Inventor: KUBOTA YUKITOSHI
IPC: C11D7/14
Filed: 2004-12-15
Abstract: <P>PROBLEM TO BE SOLVED: To provide a new liquid agent for cleaning, requiring entirely no operation for washing away, and thereby suitable for an operation for removing secretion product of a pet, and an operation for removing a dead body of an insect, excrements of a bird, etc., attached to a car body or the like.  <P>SOLUTION: The liquid agent for cleaning contains an ionized alkaline water having pH≥8.0 and ≤13.0, containing silicon, and formed at the cathode side when a raw water containing the silicon-containing material dissolved therein is subjected to electrolysis.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006169676-A (JP)
Title: Glove
Inventor: KISHIHARA HIDETOSHI
IPC: A41D19/00
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a pair of gloves high in anti-slipping effect, coating strength and abrasion resistance through coating with thermoplastic resin containing bubble.  <P>SOLUTION: This pair of gloves comprises bubble layers made from thermoplastic resin and formed in an uneven state by hot pressing on a fibrous glove base material.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006171539-A (JP)
Title: Development device, process cartridge and image forming apparatus
Inventor: SAKAI KIYOTAKA
IPC: G03G15/08
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a development device that ensures high operability, when developer stored in a developer storage section is supplied to a device main section, and to provide a process cartridge and an image forming apparatus.  <P>SOLUTION: The developing device includes the developer storage section 43 prestoring developer G to be supplied to the device main section 23h, and communicating with the device main section 23h at the upper position in the device main section 23h via an opening 43a. The opening 43a is provided with a sealing member for opening the opening 43a, when the developer G stored in the developer storage section 43 is supplied to the device main section 23h. The developer storage section 43 has a window 44 that makes it possible to view the inside of the device main section 23h via the opening 43a.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006170165-A (JP)
Title: Fuel injection control device for cylinder direct injection type internal combustion engine
Inventor: SHIINO SHUNICHI
IPC: F02D41/14
Filed: 2004-12-20
Abstract: <P>PROBLEM TO BE SOLVED: To provide a means capable of fuel injection control with a little learning error even under a stratified combustion operation condition of heavier load than conventional one in a cylinder direct injection type internal combustion engine.  <P>SOLUTION: In a cylinder direct injection type spark ignition internal combustion engine including a mode executing a plurality times of fuel injection during one cycle under stratified combustion, and a learning means S4 regulating fuel injection pulse width while performing feed back control of a target sir fuel ratio according to air fuel ratio detection value and determining learning collection value by learning relation between fuel injection pulse width and fuel injection quantity based on regulation quantity of the fuel injection pulse width, different learning correction values independently learned are reflected to a plurality of times of fuel injection respectively (S4) in the mode executing a plurality of times of fuel injection during one stratified combustion cycle.(S2 while per, S3).  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006180055-A (JP)
Title: Video photographing camera
Inventor: SHICHIJO SHUNICHI
IPC: H04N5/91
Filed: 2004-12-21
Abstract: <P>PROBLEM TO BE SOLVED: To provide a video photographing camera with excellent operability in the case of recording an image on an optical recording medium that can execute recording even when the recording capacity of the optical recording medium becomes insufficient.  <P>SOLUTION: In the video photographing camera 3 where a video recording/reproducing part for carrying out video recording and reproduction of a photographed object image on the optical recording medium at a prescribed compression rate is fitted to the side of its main body, the video recording/reproducing unit 2 includes: an output section for detecting a residual capacity of the recording capacity of the optical recording medium 1 when the residual capacity of the recording capacity of the optical recording medium 1 reaches a prescribed capacity or below during video recording and outputting a signal for informing that the residual capacity of the recording capacity reaches the prescribed capacity or below; and a switching section 5 for switching a compression rate higher than that during the present video recording on the basis of the signal detected by the output section.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006178077-A (JP)
Title: Zoom lens and imaging device
Inventor: OTAKE MOTOYUKI
IPC: G02B13/18
Filed: 2004-12-21
Abstract: <P>PROBLEM TO BE SOLVED: To provide a zoom lens obtaining stable optical quality, and also to provide an imaging device using the zoom lens.  <P>SOLUTION: The zoom lens comprises an array of: a first lens group G1 having positive refractive power; a second lens group G2 having negative refractive power; a third lens group G3 having positive refractive power; and a fourth lens group G4 having positive refractive power in the order from an object side, in which the first lens group and the second lens group are fixed in a specified state in the optical axis direction and the second lens group moves to the image side when the lens position state changes from a wide angle end state to a telephoto end state, and the fluctuation in the image plane position accompanying the movement of the second lens group by the movement of the fourth lens group is compensated. The second lens group comprises a cemented lens L22 of a negative meniscus lens L21 turning its concave surface toward the image side and a positive lens L22 turning its convex surface toward the object side arrayed in the order from the object side, and the image side lens of the negative meniscus lens is aspherical.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006176728-A (JP)
Title: Polycarbonate resin composition and medical equipment composed of the same
Inventor: TAMURA MASAKI
IPC: C08L69/00
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a polycarbonate resin composition readily identifying a liquid surface or color of contents such as a chemical fluid or blood in the interior of a medical part causing small lowering of mechanical strength and suitable as medical equipment subjected to a radiation sterilization treatment without making yellowness of a molded piece inconspicuous even when irradiated with ionizing radiation for sterilization.  <P>SOLUTION: The polycarbonate resin composition is composed of a composition obtained by compounding an aromatic polycarbonate (A) with a colorant (B) and has ≤2 color tone of a molded piece (C) on the 7th day after irradiation expressed in terms of b value according to the Hunter's Lab method when the molded piece (C) having 3 mm thickness of the composition is irradiated with the ionizing radiation. The medical equipment is composed of the polycarbonate resin composition.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006183234-A (JP)
Title: Handle
Inventor: SATO AKIHIRO
IPC: E05B1/06
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a built-in handle suitable for an opening/closing object having a different thickness.  <P>SOLUTION: According to the structure of the handle, a handle main body 42 which is fitted into a hole 44 formed in a front board 38 of a slide door 36, has a flange 46 protruded from an opening peripheral edge thereof, so as to abut on a front surface of the front board 38 when the main body 42 is fitted into the hole 44. Then the handle main body 42 has a plurality of positioning protrusions 52 formed on one side of the peripheral edge thereof, at locations being spaced a required distance away from a rear surface of the flange 46. Further the handle main body 42 has a plurality of engaging protrusions 56 protruded from the other side of the peripheral edge thereof via an elastic member 54 perpendicularly protruding from the flange 46. Furthermore each positioning protrusion 52 and each engaging protrusion 56 have inclined portions 52a, 56a on respective surfaces facing the flange 46, so as to be inclined at 45° in directions that are separated from the flange 46 at locations farther from the handle main body 42 to the outside.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006182056-A (JP)
Title: Steering gear for vehicle
Inventor: KUBOKAWA NORIKI
IPC: B62D113/00
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a steering gear for a vehicle capable of smoothly starting a system without giving a sense of incongruity to a driver on the vehicle furnished with SBW.  <P>SOLUTION: This steering device for the vehicle is furnished with a steering means to which a steering angle of the driver is input, a turning means to turn a turning wheel, a travelling state detecting means to detect a travelling state of the vehicle, a turning quantity control means to control turning quantity of the turning means in accordance with the steering angle input to the steering means and the travelling state detected by the travelling state detecting means, and the turning quantity control means computes first turning quantity in accordance with the steering angle input to the steering means, computes second turning quantity to correct the first turning quantity in accordance with the travelling state detected by the travelling state detecting means and computes final turning quantity in accordance with the first turning quantity and the second turning quantity gradually increased by fade-in control.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006183508-A (JP)
Title: Exhaust gas agitating device of internal combustion engine
Inventor: HIRANUMA SATOSHI
IPC: F01N1/08
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide an exhaust gas agitating device of an internal combustion engine capable of effectively agitating exhaust gas circulating through an exhaust passage and of controlling the increase of pressure loss in the exhaust passage by a vane.  <P>SOLUTION: A cylindrical body 21 is arranged in an exhaust passage 11 of an internal combustion engine 1. A pair of vanes 23 are erected and disposed in the body 21. While exhaust gas is guided by the vanes 23 so as to obtain agitating action through the generation of rotating flow, a communicating part 24 in which no vane 23 exists at the center of the body 21 is formed. Thus, the pressure loss by the vane 23 is reduced.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006181483-A (JP)
Title: Co selective oxidation catalyst and its manufacturing method
Inventor: AKAMA HIROSHI
IPC: B01J23/89
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a means capable of further enhancing catalytic activity under a low temperature condition and/or a high spatial speed condition in a CO selective oxidation catalyst.  <P>SOLUTION: The CO selective oxidation catalyst for selectively oxidizing carbon monoxide in a gas containing carbon monoxide and oxygen contains both of a platinum-containing catalyst powder which is obtained by supporting platinum particles containing a platinum atom and transition metal particles, which contain a transition metal atom selected from the group consisting of cobalt, manganese, nickel, copper and iron, on a first inorganic carrier and a promoter powder, which is obtained by supporting promoter particles containing a promoter atom selected from the group consisting of cobalt, manganese, nickel and copper, on a second inorganic carrier and substantially contains no platinum atom.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006185520-A (JP)
Title: Reproducing apparatus, control method, and program
Inventor: SUNAGA RYOHEI
IPC: G11B27/10
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To appropriately cope with fast forwarding indication or fast running indication from a user in the reproduction of a file to be reproduced of which the reproduction cannot be started in the middle.  <P>SOLUTION: A reproducing means 11 reproduces a file to be reproduced. A fast forwarding or fast running performing means 12 performs fast forwarding or fast running for the file to be reproduced being reproduced at present. An indication detecting means 13 detects the indication of fast forwarding or fast running from a user during the reproduction of the file to be reproduced by the reproducing means 11. A midway reproduction start possibility determination means 14 performs a reproduction start in the midway possibility determination of whether the reproduction of the file to be reproduced being reproduced at present in the reproducing means 11 can be started midway or not. An invalid time control means 16 determines the indication of fast forwarding or fast running from the user to be invalid when the midway reproduction start possibility determination is negative, and continues the reproduction of the file to be reproduced by the reproducing means 11.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006184649-A (JP)
Title: Driving device and method of light emitting display panel
Inventor: ADACHI SHINOBU
IPC: H05B44/00
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To reduce shadowing and luminance slope occurring according to the lighting rates of light emitting elements.  <P>SOLUTION: The driving device includes a passive matrix type light emitting display panel 1 equipped with the light emitting elements E11 to Emn connected to the intersection positions of a plurality of scanning lines and a plurality of data lines intersecting each other, changeover means Sal to Sam on a scanning driver 3 side where each of the scanning lines A1 to Am is set at a scanning selection potential VAH or non-scanning selection potential (grounding potential), and changeover means Sk1 to Skn on a data driver 2 side where each of the data lines K1 to Kn is connected to lighting drive power sources I1 to In or non-lighting drive power source VKH. The lighting drive power sources I1 to In comprise a constant current source of an attraction type to attract the lighting drive current of the light emitting elements from a cathode terminal side of the light emitting elements in a scanning state toward a reference potential point.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006182540-A (JP)
Title: Portable terminal device storage/management method, its device and storage box to be used for the same
Inventor: FUKUDA TAKESHI
IPC: B65G1/137
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a portable terminal device storage/management method, its device and a storage box to be used for the same, for allowing the seizure of the storage condition of a terminal device.  <P>SOLUTION: A power outlet 39 is mounted on a storage rack 40 for charging the terminal device 30 when stored. An electronic lock mechanism 16 is provided for an opening/closing door which is controlled to be locked/unlocked by the storage/management device 10B. The storage box is completely managed because the opening/closing of the storage box is permitted only by a specific man. A storage condition display panel 18 is provided on the front face of a storage box body 12 for reflecting and displaying the storage condition of the terminal device on a display part. The storage condition is easily confirmed from the outside without opening the storage box.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006188772-A (JP)
Title: Wearing article unit, cloth and cloth unit
Inventor: ANDRZEJ BULLER
IPC: A41D27/00
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a wearing article unit enabling a wearer to communicate richer with other persons presenting around the wearer.  <P>SOLUTION: This T-shirt unit 1 is equipped with a cloth 10, a sensor 30 attached with the cloth 10 and detecting the living body information of the user, and a displaying part 20 for displaying information showing the state of the user based on the detected information on the surface of the cloth 10.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005529452-A (JP)
IPC: F21Y101/00
Filed: 2002-06-07
Abstract: A lamp assembly configured to inductively receive power from a primary coil. The lamp assembly includes a lamp circuit including a secondary and a lamp connected in series. In a first aspect, the lamp circuit includes a capacitor connected in series with the lamp and the secondary to tune the circuit to resonance. The capacitor is preferably selected to have a reactance that is substantially equal to or slightly less than the reactance of the secondary and the impedance of the lamp. In a second aspect, the lamp assembly includes a sealed transparent sleeve that entirely encloses the lamp circuit so that the transparent sleeve is fully closed and unpenetrated. The transparent sleeve is preferably the lamp sleeve itself, with the secondary, capacitor and any desired starter mechanism disposed within its interior.
Patent JP-2005524427-A (JP)
Title: 多用途ケース
IPC: A45D33/36
Filed: 2003-04-24
Abstract: 【課題】組立工程が容易であり且つ芯の引き出しが容易である多用途ケースを提供する。 【解決手段】ケースの内部に備えられた化粧用または文具用芯を外部に引き出して使用するための多用途ケースは、所定の長さの筒状の第１管が外嵌された第１支持部と、前記第１支持部の両側に長手方向に垂直に立設される連結部材と、前記連結部材の上端に設けられ、外周には前記第１管より小さい外径の第２管が外嵌される第２支持部とからなるケースと、前記ケースに外嵌した第１管と第２管との間に備えられる第３管の下端に結合し、上端に備えられた芯を出没させるための芯固定具とを含んでなる。
Patent JP-2005530755-A (JP)
IPC: C07D307/33
Filed: 2003-04-25
Abstract: The present invention relates to a process for preparing unsubstituted or C<SUB>1</SUB>-C<SUB>4</SUB>-alkyl-substituted gamma-butyrolactone by catalytic hydrogenation of maleic acid and/or its derivatives in the presence of chromium-free catalyst comprising from 10 to 80% by weight of copper oxide and from 10 to 90% by weight of at least one catalyst support selected from the group consisting of silicon dioxide, titanium dioxide, hafnium dioxide, magnesium silicate, activated carbon, silicon carbide, zirconium dioxide and alpha-aluminum oxide.
Patent JP-2005535592-A (JP)
Title: 置換されたキノロンカルボン酸、その誘導体、作用の部位、およびその使用
IPC: A61P25/02
Filed: 2003-05-12
Abstract: 置換されたキノロンカルボン酸およびその誘導体を記載する。ＧＡＢＡ Ａ 受容体複合体の新規部位を介して、これらの化合物は、γ−アミノ酪酸（ＧＡＢＡ）の効果を、治療上関連性のある様式で変調し、これらの化合物を使用して、ＧＡＢＡ Ａ 受容体複合体の変調に対して受容性のあるＣＮＳ障害を寛解することが可能である。
Patent JP-2005527949-A (JP)
Title: 照明式画像ランプ
IPC: F21Y101/00
Filed: 2003-05-20
Abstract: 【解決手段】  画像ディスプレイ装置（１４０）は、選択可能且つ取り外し可能に取り付けることのできる基部上の光源によって画像を照らす手段を提供している照明式絵画ランプの形態を取っている。望ましくは透明な材料（１４２）で取り囲まれている半透明材料（１４０）の基層を使って、画像を、光源（１１２）で照らされている２つの層の間に滑り込ませる。シートを使ってランプシェードを形成し、シートは、白熱電球の様な光源の周りの所定の位置に、取り付け基部（１０８）にねじ係合されている支持部によって保持されている。取り付け基部は、白熱電球（１７０）の概略下方でランプに取り付けられ、ランプシェード用の安定した支持部を形成している。本発明の画像ディスプレイ装置は、光源と、個人の好みに合わせて装飾されたランプシェードの様な製品によって画像を照らす魅力的且つ選択可能な手段を提供する。
Patent JP-2005527166-A (JP)
IPC: H01L27/092
Filed: 2003-05-23
Abstract: An integrated circuit including a Multi-Threshold CMOS (MTCMOS) latch combining low voltage threshold CMOS circuits with high voltage threshold CMOS circuits. The low voltage threshold circuits including a majority of the circuits in the signal path of the latch to ensure high performance of the latch. The latch further including high voltage threshold circuits to eliminate leakage paths from the low voltage threshold circuits when the latch is in a sleep mode. A single-phase latch and a two-phase latch are provided. Each of the latches is implemented with master and slave registers. Data is held in either the master register or the slave register depending on the phase or phases of the clock signals. A multiplexer may alternatively be implemented prior to the master latch for controlling an input signal path during sleep and active modes of the latch and for providing a second input signal path for test.
Patent JP-2005528491-A (JP)
Title: 連続した広い発光波長を有する光源及びそのために有用なリン光体組成物
IPC: C09K11/08
Filed: 2003-05-06
Abstract: 約４００から約１５００ナノメートル以上の範囲の連続的な発光波長を有するリン光体混合物（３２）は、無機リン光体から製造できる。このようなリン光体混合物（３２）は、光源（３０）又は電子ビーム（４６）発生器とともに光源として使用され、広範囲の発光波長を生成することができる。かかるリン光体は、身体の光透過部分、例えば耳たぶにリン光体光を発光させ、そしてグルコース濃度を測定することにより、ヒトの血糖濃度を決定するために使用することもできる。
Patent JP-2005529054-A (JP)
IPC: B60S1/56
Filed: 2003-06-04
Abstract: The present invention relates to an electrically heatable glazing panel comprising a substantially transparent, electrically conductive coating layer which is adapted to be electrically heatable and is divided into a plurality of zones, some heatable and some non-heatable. The glazing panel according to the invention is preferably a side window which may be used for de-misting or de-icing purposes.
Patent JP-2006501191-A (JP)
Title: キナーゼ阻害剤としてのヘテロ二環式ピラゾール誘導体
IPC: C07D307/68
Filed: 2003-07-11
Abstract: 【課題】キナーゼ阻害剤としてのヘテロ二環式ピラゾール誘導体 【解決手段】本明細書で定義される式（Ｉ）の二環式ピラゾール、及び薬学的に許容されるそれらの塩、それらの調製方法、及び、それらを含有する薬学的粗製物が開示される；本発明の化合物は、制御されないタンパク質キナーゼ活性に関する疾患、例えば癌の治療処置において有用である。   【化１】
Patent JP-2005538979-A (JP)
Title: キナーゼ阻害剤としてのトキソフラビンの３−フェニル類似物
IPC: A61K31/5377
Filed: 2003-07-08
Abstract: 本発明は、式（Ｉ） 【化１】     ［式中、ｎは０、１または２の整数を表し、ｍは０または１の整数を表し、Ｒ １ はＣ １−４ アルキルを表し、Ｒ ２ はＣ １−４ アルキルを表し、Ｒ ３ はＣ １−４ アルキルを表すか、或はＲ ２ とＲ ３ がこれらが結合している炭素原子と一緒になってＣ ３−８ シクロアルキルまたはＨｅｔ １ を形成しており、ここで、前記Ｃ ３−８ シクロアルキルまたはＨｅｔ １ は各々独立して場合によりＣ １−４ アルキルオキシカルボニルで置換されていてもよく、Ｒ ４ はハロまたはＣ １−４ アルキルオキシを表し、Ｒ ５ はＣ １−４ アルキルオキシカルボニル、−Ｏ−（モノ−もしくはジ（Ｃ １−４ アルキル）アミノスルホニル）；Ｈｅｔ ３ またはＮＲ ６ Ｒ ７ から選択される１個または可能ならばそれ以上の置換基で置換されているＣ １−４ アルキル；アミノ、Ｈｅｔ ４ またはＮＲ ８ Ｒ ９ から選択される１個または可能ならばそれ以上の置換基で置換されているＣ １−４ アルキルオキシを表し、Ｒ ６ およびＲ ７ は各々独立して水素、Ｃ １−４ アルキル、Ｃ １−４ アルキルオキシＣ １−４ アルキル、−Ｈｅｔ ５ ；またはヒドロキシまたはＨｅｔ ５ から選択される１個または可能ならばそれ以上の置換基で置換されているＣ １−４ アルキルから選択され、Ｒ ８ およびＲ ９ は各々独立して水素、Ｃ １−４ アルキル、−Ｈｅｔ ７ またはモノ−もしくはジ（Ｃ １−４ アルキル）アミノスルホニルから選択され、Ｈｅｔ ３ はピペリジニルまたはピペラジニルから選択される複素環を表し、ここで、前記単環状複素環は各々が独立して場合により各々がヒドロキシ、アミノスルホニル、アミノ、モノもしくはジ（Ｃ １−４ アルキル）アミノスルホニル、ヒドロキシＣ １−４ アルキルオキシＣ １−４ アルキルまたはＣ １−４ アルキルオキシから独立して選択される１個または可能ならば２または３個の置換基で置換されていてもよく、Ｈｅｔ ４ はモルホリニル、ピペリジニルまたはピペラジニルから選択される複素環を表し、ここで、前記単環状複素環は各々が独立して場合により各々がＣ １−４ アルキル、Ｃ １−４ アルキルオキシカルボニルまたはモノもしくはジ（Ｃ １−４ アルキル）アミノスルホニルから独立して選択される１個または可能ならば２または３個の置換基で置換されていてもよいく、Ｈｅｔ ５ はピリジニルまたはピペリジニルから選択される複素環を表し、ここで、前記単環状複素環は各々が独立して場合により各々がアミノスルホニルまたはモノ−もしくはジ（Ｃ １−４ アルキル）アミノスルホニルから独立して選択される１個または可能ならば２または３個の置換基で置換されていてもよく、Ｈｅｔ ７ はピペリジニルを表す］ で表される化合物、これらのＮ−オキサイド形態、製薬学的に受け入れられる付加塩および立体化学異性体形態に関する。
Patent JP-2005532815-A (JP)
Title: 皮膚疾患の修正のためのスプライセオソームにより媒介されるｒｎａトランススプライシング
IPC: A61K48/00
Filed: 2003-07-17
Abstract: 本発明は、ターゲティングされた、スプライセオソームにより媒介されるRNAトランススプライシングにより新規な核酸分子を作製するための方法および組成物を提供する。本発明の組成物は、標的前駆体メッセンジャーRNA分子（標的プレmRNA）と相互作用し、新規なキメラRNA分子（キメラRNA）の生成をもたらすトランススプライシング反応を媒介するようデザインされたプレトランススプライシング分子(PTM)を含む。特に、本発明のPTMは、皮膚細胞で発現された特定の標的プレmRNAと相互作用し、その結果、種々の異なる皮膚疾患の原因となる遺伝的欠陥の修正をもたらすよう遺伝子操作して、治療上の価値を有し得るレポーター分子またはタンパク質をコードするようにすることができる。本発明の組成物はさらに、本発明のPTMを発現することができる組換えベクター系および該PTMを発現する細胞を含む。本発明の方法は本発明のPTMと、皮膚細胞で発現した特定の標的プレmRNAとを、該PTMの一部が標的プレmRNAの一部にトランススプライシングされてその特定の遺伝子の遺伝的欠陥が修正されたキメラRNA分子を形成する条件下で、接触させることを含む。本発明はコラーゲンXVIIプレmRNAのトランススプライシングが上手くいき、それにより皮膚特異的な遺伝的欠陥の修正のためのトランススプライシングの有用性が確立されることに基づくものである。本発明の方法および組成物は、特定の皮膚疾患、すなわち、上皮脆弱性疾患、角質化疾患、毛髪疾患および色素沈着疾患などの遺伝性皮膚症、ならびに皮膚の癌の治療のための遺伝子療法に使用できる。
Patent JP-2006502752-A (JP)
Title: 粉末状物質の手動操作吸入器
IPC: A61J7/02
Filed: 2003-06-30
Abstract: 【課題】  改善され機能を有する吸入器を提供する。 【解決手段】  本発明は粉末状物質、特に薬剤物質用の手動操作吸入器（１）において、手動操作によってある一定の投与量（２０’）を、排出ダクト（２１）の端部（ｂ）の口金開口部（１４）から空気で搬送するため、物質の貯蔵量（２０）から排出ダクトの手前の計量室（Ｄ）に分離し、排出のための空気流を発生するピストン（８）は、その円筒部（１５）の中空空間（１７）とともに物質の貯蔵室（ＳＶ）および計量室（Ｄ）を形成し、ピストン（８）の戻りストロークによって発生する負圧が、計量室（Ｄ）を物質の貯蔵量（２０）に対して開放し、さらに計量室（Ｄ）の底は空気透過性の膜によって形成させ、粉末状物質を細かく分散して運搬する強力な空気流を発生させるため、ピストンの運動によって発生する空気量が計量室（Ｄ）の容積の１００倍より多く、６００倍より少なくすることを提案している。
Patent JP-2006504409-A (JP)
Title: 鏡像異性のエクオールを含有する組成物および製品、およびその製造方法
IPC: A23L33/00
Filed: 2003-07-24
Abstract: S−エクオール、R−エクオール、またはS−エクオールおよびR−エクオールの非ラセミ体およびラセミ体を含む混合物よりなる市販食品および皮膚用製品の製造に用いられる組成物。当該組成物は、例えば食品サプリメント、医薬品および医薬的組成物等の市販品を製造するために使用できる。当該組成物は、心血管疾患、脂質障害、骨減少症、骨粗鬆症、肝臓疾患、および急性の卵巣エストロゲン不足等のホルモン依存性疾患を含む疾患または関連した状態を防止または治療するために哺乳類にS−エクオールを投与する方法に有用である。当該S−エクオール鏡像異性体は微生物によるイソフラボンの代謝から生合成によって製造することができる。