baber/WOPTO huggingface dataset:
Patent NZ-215259-A (NZ)
Title: Renaturation of somatotropin
Inventor: BENTLE L A
IPC: C07K14/61
Filed: 1986-02-21
Abstract: A method for solubilization and naturation of somatotropin protein from refractile bodies of host cells is disclosed. The method embraces the discovery that an aqueous urea or dimethylsulfone solution can be effectively used to solubilize refractile bodies containing such somatotropin protein. Once solubilized, somatotropin protein can be natured in a urea or dimethylsulfone solution by contacting the solution with a mild oxidizing agent for a time sufficient to result in the formation of the disulfide bonds. Naturation can efficiently occur even at high protein concentration, in an impure preparation and in the absence of reducing agent.
Patent NZ-221046-A (NZ)
Title: Interleukin-3 and interleukin-3 like polypeptides from primates, pharmaceutical compositions and recombinant methods for producing the polypeptides
Inventor: CLARK STEVEN C
IPC: C12N15/27
Filed: 1987-07-13
Abstract: A novel family of primate IL-3-like polypeptides is provided via recombinant techniques.
Patent NZ-225176-A (NZ)
Title: Nucleoside derivatives
Inventor: HARALAMBIDIS JIM
IPC: C07H19/073
Filed: 1988-06-24
Abstract: A nucleoside derivative of formula (1), characterized in that: Y is H or OH or a protected hydroxy group; X is H, a phosphonate group or a phosphoramidite group of formula (II), where R1 and R2 are the same or different, and are selected from alkyl and substituted alkyl, which may be branched or unbranched; and Q is a phosphate protecting group; Z is H, a phosphate or triphosphate group or hydroxy protecting group; X' is a C1-15 alkyl group which may be branched or unbranched; R is an amino protecting group or a fluorophore, or other non-radioactive detectable marker; or the group Y'NHA, where Y' is an alkyl (C1-40) carbonyl group which may be branched or unbranched, and A is an amino protecting group or a fluorophore or other non-radioactive detectable marker. Methods for the synthesis and sequencing of polynucleotides utilizing compounds of formula (I).
Patent NZ-230206-A (NZ)
Title: Dna construct comprising the chlorophyll a/b (cab) binding protein gene from zea mays, for the expression of exogenous dna
Inventor: ELY SUSAN
IPC: A01H5/00
Filed: 1989-08-04
Abstract: The gene promoter which drives expression of the chlorophyll antibody (CAB) protein in the green tissue of plants has been isolated and sequenced enabling use of the promoter, by recombinant DNA techniques, for green tissue specific expression of an exogenous gene by transformation of a plant with the a recombinant DNA in which the CAB promoter is fused to the exogenous gene. Particularly useful applications of the CAB promoter are in the expression of insecticidal toxins, such as a  delta -endotoxin of Bacillus thuringiensis, to provide protection of the plant from predation by insects which attack the green tissue, and in the expression of mRNA which is anti sense to mRNA expressed by an endogenous gene so as to suppress translation of the endogenous mRNA to protein.
Patent NZ-234099-A (NZ)
Title: Solid-liquid contact apparatus with vertical wire filter screen at liquid outlet
Inventor: MOORMAN CHARLES T
IPC: B01J8/20
Filed: 1990-06-18
Abstract: A screen (14) is mounted in an apparatus for contacting particulate solids with a fluid. The apparatus comprises an elongate column (10) for holding a bed of particulate solids for contact with a fluid, the column being designed to be oriented substantially vertically in use and having a fluid inlet (11) near the bottom for admitting a fluid into the column and a fluid outlet (13) near the top for permitting the fluid to exit the column after passing upwardly through a bed of particulate solids in the column. The purpose of the screen (14) is to screen solids from the fluid exiting the column through the fluid outlet (13). The screen (14) comprises a plurality of vertical screen wires (15), and the screen is located within the column such that all of the fluid passing through the column passes through the screen (14) and thence through the fluid outlet (13). Each pair of adjacent vertical screen wires (15) defines a substantially vertical screen slot (20) therebetween. The opening of each vertical screen slot (20) at the surface of the screen (14) which is upstream in the sense of a fluid flowing through the column (10), passing through the screen (14), and exiting through the outlet (13) during operation of the column (10), has a width suitable for screening solids from the exiting fluid and has a length which is substantially greater than its width.
Patent NZ-253668-A (NZ)
Title: Case and method for disinfecting contact lenses with hydrogen peroxide then neutralising peroxide with a catalase tablet
Inventor: NIELSEN TOM BURIS
IPC: A01N59/00
Filed: 1993-06-28
Abstract: PCT No. PCT/DK93/00211 Sec. 371 Date Mar. 29, 1995 Sec. 102(e) Date Mar. 29, 1995 PCT Filed Jun. 28, 1993 PCT Pub. No. WO94/01800 PCT Pub. Date Jan. 20, 1994A method and case for disinfection of contact lenses wherein the contact lenses are placed in a double chamber filled with cleaning fluid, for example, hydrogen peroxide, with the case comprising a third chamber or position connected with the double chamber. The third chamber is adapted to take up and hold a tablet containing a neutralization agent such as catalase, so that the hydrogen peroxide in the double chamber is neutralized suitably slowly by admission of the cleaning fluid to dissolve the tablet. By the dissolution of the tablet, oxygen is generated, and an oxygen bubble is formed around the tablet so that the hydrogen peroxide is alternately kept from the tablet and ultimately is admitted access to the tablet. Rather than provide a double chamber, a holder member may be provided for holding the respective contact lenses, with the tablet being accommodated at a lower end of the holder and being exposed to the cleaning fluid when the holder is inserted into the cleaning fluid.
Patent NZ-263595-A (NZ)
Title: Inhalator; details of a movable shutter providing improved medicament moisture protection
Inventor: DROUGHT NICHOLAS ANDREW MURRAY
IPC: A61M13/00
Filed: 1994-03-31
Abstract: PCT No. PCT/GB94/00712 Sec. 371 Date Jan. 2, 1996 Sec. 102(e) Date Jan. 2, 1996 PCT Filed Mar. 31, 1994 PCT Pub. No. WO94/22515 PCT Pub. Date Oct. 13, 1994A medication inhalation device includes a housing having a through-going pathway connecting an air inlet with an air outlet, a medicament reservoir adapted to receive a compacted body of powdered medicament, and metering means for dispensing a predetermined dose of medicament from the reservoir into the through-going pathway, the metering means including means for abrading the compacted body; the device is provided with a shutter movable between a first position in which the compacted body is isolated from the through-going pathway and a second position in which the compacted body is in communication with the through-going pathway wuch that a dose of medicament can be dispensed from the reservoir into the through-going pathway.
Patent NZ-265278-A (NZ)
Title: Use of polyarylene thioether-based filter material for the removal of ozone from fluids
Inventor: STRUTZ HEINZ
IPC: B01J20/26
Filed: 1994-04-13
Abstract: A filter material based on a polyarylene thioether having repeating units of the formula -[(Ar1)n-X)]m-[(Ar2)i-Y)]j-[(Ar3)k-Z)]l-[(Ar4)o-W)]p-(I) in which Ar1, Ar2, Ar3, Ar4, W, X, Y and Z, independently of each other, are identical or different, the indices n, m, i, j, k, l, o and p, independently of each other, are zero or integers 1, 2, 3 or 4, their sum being at least 2, Ar1, Ar2, Ar3 and Ar4 are arylene systems having 6 to 18 carbon atoms, and W, X, Y and Z are divalent linking groups, selected from -SO2-, -S-, -SO-, -CO-, -O-, -CO2-, or alkylene groups or alkylidene groups having 1 to 6 carbon atoms is suitable for removing ozone from gases or liquids. The removal proceeds quantitatively, no volatile products being formed.
Patent NZ-314657-A (NZ)
Title: Linguistic analysis of document with portions tagged to indicate special translation requirements
Inventor: GALLUP SHARLENE LOU
IPC: G06F17/27
Filed: 1993-08-23
Abstract: The present invention is a system of integrated, computer-based processes for monolingual information development. and multilingual translation. An interactive text editor enforces lexical and grammatical constraints on a natural language subset used by the authors to create their text, which they help disambiguate to ensure translatability. The resulting translatable source language text undergoes machine translation into any one of a set of target languages, without the translated text requiring any postediting.
Patent NZ-335807-A (NZ)
Title: Padded wrap to be placed between a limb and a tourniquet
Inventor: BASKA KANAG
IPC: A61B19/00
Filed: 1999-05-17
Abstract: Protective means 10, for placement under a tourniquet, includes a padded body 11 and a liquid resistant sheet 12 having a first and a second portion extending outwardly from respectively a first and a second side edge of the padded body.  The sheet is designed to extend about the limb of a patient and thereafter to be folded back over a tourniquet positioned on the padded body.
Patent NZ-502963-A (NZ)
Title: Thiourea and benzamide compounds and methods of treating or preventing inflammatory diseases and atherosclerosis
Inventor: SORENSON RODERICK JOSEPH
IPC: C07D277/36
Filed: 1998-11-20
Abstract: Compounds of formula III wherein: Re is pyridyl;, or phenyl that is substitutes with from 1 to 5 substituents selected from halogen, -CF3, -NO2, benzoyl, -SO3 alkali metal, C1-6alkyl -OC1-6alkyl, -CN, -COOH, -SO3H, -OCF3, C(O)C1-6alkyl, C(O)OC1-6alkyl, SO2NH2, N(C1-6alkyl)2 or SONH2; B is OC1-6 alkyl, H, halogen or C1-6alkyl; Y is of the remaining formula provided; Q is phenyl, pyridyl, or phenyl substituted with 1-5 substituents selected from halogen, -OC1-6alkyl, or C1-6alkyl or the pharmaceutically acceptable salts thereof. The compounds are useful in inhibiting the chemotaxis of monocytes.
Patent NZ-503316-A (NZ)
Title: Polypeptide and nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
Inventor: LIM ENG-MONG
IPC: C12N15/31
Filed: 1998-08-14
Abstract: Recombinant screening, cloning and/or expression vector that replicates in mycobacteria, comprising: (i)    A replicon functional in mycobacteria; (ii)   A selectable marker; and (iii)   A reporter cassette comprising: a.    A multiple cloning site (polylinker); b.    Optionally a mycobacterial transcription terminator which is active in mycobacteria, upstream of the polylinker; c.     A coding nucleotide sequence derived from a gene encoding a protein expression, export and/or secretion marker, the coding sequence lacking its initiation codon and its regulatory sequences; and d.    A coding nucleotide sequence derived from a gene encoding maker for the activity if promoters which are contained in the same fragment, the sequence lacking its initiation codon.
Patent NZ-504913-A (NZ)
Title: Vending machine for vertically stacked goods that dispenses the lowest item
Inventor: CLEEVE KEITH FRANCIS
IPC: G07F7/08
Filed: 1998-12-10
Abstract: A vending machine is disclosed that is particularly suited to regular shaped items such as compact disks. Included are input means for selecting the item, payment means, a vending unit, and a control means linking the previous unit and means for determining that correct payment has been made for the item chosen, and allowing that item to be dispensed. In the vending unit, items are stacked vertically in a plurality of storage compartments, associated with a latch that can move to dispense the lowest item whilst preventing the next item from dropping until the latch returns to its original position. The items are stacked in such a way that a portion of the lower surface of an item extends beyond the upper surface of the item below. When the item to be dispensed is released by the latch, it drops into carriage movable in relation to the storage compartments that dispenses the item.
Patent NZ-516785-A (NZ)
Title: Catheter for uniform delivery of medication
Inventor: DENIEGA JOSE CASTILLO
IPC: A61M25/00
Filed: 2000-07-19
Abstract: The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with some embodiments, the catheter includes an elongated tubular member made of a porous membrane. The porous membrane is configured so that a fluid introduced into an open end of the tubular member will flow through side walls of the tubular member at a substantially uniform rate along a length of the tubular member. In accordance with other embodiments, the catheter includes an elongated "weeping" tubular coil spring attached to an end of, or enclosed within, a tube. Fluid within the spring and greater than or equal to a threshold pressure advantageously flows radially outward between the spring coils. Advantageously, the fluid is dispensed substantially uniformly throughout a length of the spring. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region.
Patent NZ-522532-A (NZ)
Title: Hydrogel composition for transdermal drug delivery
Inventor: KIM HO CHIN
IPC: A61P25/04
Filed: 2001-05-15
Abstract: A hydrogel composition for transdermal drug delivery is disclosed, wherein the hydrogel composition comprises a hydrophilic polymer base, a drug, a lipophilic permeation enhancer, water as a solvent and a compatibilizer consisting essentially of an acrylate polymer which compatibilizes said lipophilic enhancer with said hydrophilic polymer base and which renders said composition thermodynamically stable; and wherein the acrylate polymer compatibilizers such as acrylic acid polymer, methacrylic acid polymer, alkyl acrylate polymer, alkyl methacrylate polymer or copolymers thereof enable both hydrophilic and lipophilic permeation enhancers to be applicable in the hydrogel composition in order to effectively control skin penetration of drugs.
Patent NZ-522923-A (NZ)
Title: Feline hepatocyte growth factor
Inventor: MIYAKE MASASHI
IPC: A61P13/12
Filed: 2001-05-30
Abstract: Described is a feline hepatocyte growth factor having the amino acid sequence of SEQ ID NO:2 and 5 amino acid deleted fHGF having the SEQ ID NO:4. Also described are, DNA sequence encoding the protein, vectors, methods of producing the growth factor, and pharmaceutical compositions comprising the growth factor for the treatment of liver diseases, kidney diseases, lung diseases, bone diseases, digestive diseases, cardiocirulatory diseases or cranial nerve diseases.
Patent NZ-524618-A (NZ)
Title: Proline derivatives and use thereof as drugs
Inventor: KITAJIMA HIROSHI
IPC: C07D487/04
Filed: 2001-08-10
Abstract: An L-proline derivative of formula (I) where: - X is -NR1R2 where o R1 and R2 may be the same or different, and each is independently a hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, or may be bonded to each other to form a heterocycle optionally containing 1 or 2 nitrogen atoms or oxygen atoms, the heterocycle optionally being condensed with an aromatic ring optionally having substituents, and the heterocycle optionally being a spiro ring; - -NR3COR4 where R3 and R4 are the same or different and each is independently a hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, arylalkenyl, heteroaryl or heteroarylalkyl; - -NR5CONR6R7 or -NR5CH2CH2NR6R7 where R5, R6 and R7 are the same or different and each is independently hydrogen, alkyl, acyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, arylalkenyl, heteroaryl or heteroarylalkyl, or R6 and R7 may be bonded to each other to form a heterocycle optionally containing 1 or 2 nitrogen atoms or oxygen atoms, the heterocycle optionally being condensed with an aromatic ring optionally having substituents; - -NR8So2R9 where R8 and R9 are the same or different and each is independently a hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl; or - -OR10 or -OCOR11 where R10 and R11 are each a hydrogen atom, alkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl; - Y is CH2, CH-OH, S, S=O or SO2; - Z is a hydrogen or a cyano, and - Each of the above mentioned groups - alkyl, aryl, arylalkyl, arylalkenyl, heteroaryl, heteroarylalkyl, cycloalkyl, cycloalkylalkyl and heterocycle each optionally have substituents. The abovementioned compounds have a DPP-IV inhibitory action, and may be useful in treating or preventing diabetes, obesity, HIV infection, cancer metastasis, dermopathy, prostatic hyperplasia, periodontitis or autoimmune disease.
Patent NZ-524745-A (NZ)
Title: Pyridazinones and triazinones and medicinal use thereof
Inventor: NAGATO SATOSHI
IPC: C07D237/24
Filed: 2001-09-17
Abstract: Disclosed are compounds of formula (I), wherein: A1, A2 and A3 are independently cycloalkyl, cycloalkenyl, non-aromatic heterocycle, aromatic hydrocarbon heterocycle, which may be substituted, Q is O, S or NH, Z is C or N, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for the treatment or prevention of diseases in which an AMPA receptor or kainite receptor is participated.
Patent NZ-526312-A (NZ)
Title: Combinatorial libraries of proteins having the scaffold structure of C-type lectin-like domains
Inventor: ETZERODT MICHAEL
IPC: C07K14/47
Filed: 2001-12-13
Abstract: A family of protein libraries comprising CTLDS (C-type Lectin-Like Domains) in which internal polypeptide loop-regions lining the ligand binding sites in CTLDs have been replaced with ensembles of completely or partially randomised polypeptide segments. Tetranectin CTLDs were chosen as framework for the preferred embodiment; and versatile phagemid vectors useful in the generation and manipulation of human and murine tetranectin CTLD libraries are disclosed. Tetranectin CTLDs in monomeric as well as in trimeric form are efficiently displayed as gene III fusions in fully functional form by the recombinant fd phage display vector. CTLD derivatives with affinity for new ligands may readily be isolated from libraries of vectors displaying CTLDs, in which loop-regions have been randomised, using one or more rounds of enrichment by screening or selection followed by amplification of the enriched subpopulation in each round. The efficiency with which protein products containing CTLDs with new binding properties can be produced, e.g. by bacterial expression in in vitro refolding, in mono-, tri-, or multimeric formats provides important advantages in terms of simplicity, cost and efficiency of generation, production and diagnostic or therapeutic applications in comparison to recombinant antibody derivatives.
Patent NZ-526447-A (NZ)
Title: Decision support system and method implemented using an additive points system
Inventor: OMBLER FRANZ
IPC: G06F19/00
Filed: 2003-06-13
Abstract: A decision support system comprises two or more pre-defined criteria stored in data memory, each criterion capable of being instantiated with one or more pre-defined and ordinally ranked categories, and a processor programmed to perform a comparative assessment of profiles each profile comprising a set of two or more of the criteria, each criterion in the set instantiated with one of the categories for that criterion. The comparative assessment comprises the ordinal pairwise ranking of profile pairs, the ordinal pairwise ranking of profile pairs comprises the steps of generating undominated profile pairs; presenting undominated profile pairs to a decision maker on a display; receiving from the decision maker via an input device an ordinal ranking of the profiles in each profile pair presented on the display, and identifying profile pairs that are implicitly ordinally pairwise ranked as corollaries of ordinal pairwise rankings performed and excluding them from subsequent presentation to the decision maker. The processor is further programmed to solve a system of equalities/inequalities that represents the ordinal pairwise rankings to obtain at least one output. An undominated profile pair can be referred to as an ambiguous profile pair or a dilemma. An undominated profile pair profile pairs are profile pairs where one profile has a higher categorical rating on at least one criterion and a lower rating on at least one other criterion that the other profile.
Patent NZ-527535-A (NZ)
Title: Method of indexing data in a multidimensional database such as an OLAP product
Inventor: SANDERS MICHAEL JOHN
IPC: G06F17/30
Filed: 2003-08-11
Abstract: A method of indexing data in a multidimensional database that comprises:- (a) Creating a multidimensional logical access model; (b) Creating a multidimensional data storage model in which data located in cells is stored and retrieved in blocks; (c) Gathering data access information derived from one or more user queries of the database; and (d) Reorganizing one or more selected cells in the multidimensional data storage model based on the data access information to reduce the cost of access to the one or more selected cells in response to a user query of the database.
Patent NZ-531736-A (NZ)
Title: Defrosting heater, and refrigerator having the defrosting heater
Inventor: ONISHI ICHIRO
IPC: F25D21/08
Filed: 2002-07-03
Abstract: A defrosting heater for heating and removing frost deposits collected and adhered on a cooler of a refrigeration cycle packed with a flammable refrigerant, comprising a glass tube (53), a heater wire (53) of metal resistance element installed in the glass tube, a plug (58) covering both end openings of the glass tube (53), a lead wire (55) penetrating through the plug (58) and connected to the end of the heater wire (53), and a positioning plate disposed at the junction and held by the plug for preventing the junction of the heater wire and lead wire from moving, wherein the size of the gap (58b) formed between the plug (58)and the positioning plate (59) is set depending on the packing amount of the flammable refrigerant and a preset surface temperature of the heater wire (53).
Patent NZ-535580-A (NZ)
Title: A luminaire lamp socket mounting arrangement
Inventor: CRONK PAUL ANDREW
IPC: F21V7/16
Filed: 2003-02-26
Abstract: A lamp socket mounting for a doubly arched reflector luminaire is disclosed. The luminaire has a reflector formed from two leaves that extend from a V-shaped spine. The mounting has a bight-shaped base (121) able to be mounted on the spine, and a pair of arms (124) that extend from the base in a direction away from the bight (122). A housing (133) is located between the arms, and is able to be moved longitudinally along the arms. A fastening means (137) is provided to locate the housing in place.
Patent NZ-541147-A (NZ)
Title: Acylaminothiazole derivatives, preparation method thereof and use of same as beta-amyloid peptide production inhibitors
Inventor: DESPEYROUX PIERRE
IPC: C07D417/12
Filed: 2004-01-22
Abstract: Disclosed is a compound of formula (I), wherein X represents O or S and the remaining substituents are as defined in the specification. The compounds are inhibitors of beta-amyloid peptides including beta-A4 and are useful in the treatment of senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementia and Pick's disease, post-traumatic dementia, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.