baber/WOPTO huggingface dataset:
Patent NZ-711416-A (NZ)
Title: Drug delivery devices and methods for drug delivery
Inventor: LEE HEEJIN
IPC: A61K31/167
Filed: 2014-03-14
Abstract: This disclosure generally relates to implantable devices for controlled drug delivery without a pre-defined orifice. Many current drug delivery devices rely on at least one orifice to permit the release of drugs from the devices. While an orifice may allow for some control over drug release, orifice-containing devices may potentially expel an undesirable amount of drug when compressed after deployment. For example, an orifice-containing device deployed in the bladder may be compressed during bladder contraction, thereby forcing an undesirable amount of drug out of the orifice. The compression of orifice-containing devices may release toxic amounts of drugs, especially when the drugs are potent, such as anti-cancer drugs. This problem can be mitigated, to some degree, by decreasing the size of the orifice of a particular device. As the size of the orifice decreases, however, the likelihood that the orifice will clog after deployment increases. A clogged orifice is undesirable because it often leads to less reproducible drug release, or it may prevent drug release entirely. Aside from possible mechanical difficulties, adding an orifice to a device increases the device’s complexity and cost of the components and/or manufacturing. This is especially true when an orifice of a small and precise diameter, such as one ranging from 75 to 300 microns, is needed to ensure that the device is capable of releasing drug at a desired rate. In other cases, a drug delivery device may not have a release orifice and release of drug is controlled by diffusion from a matrix material and/or through a wall. Such configurations which rely on diffusion, however, may limit the drug release kinetics that can be achieved and/or may limit the range of suitable materials of construction to ones that lack the desired biocompatibility, stability, sterilizability, and mechanical properties, including manufacturability, wall thickness, flexibility, etc. There exists a need for a drug delivery device that overcomes one or more of these disadvantages. An orifice-free drug delivery device is provided. In an embodiment, the device includes a body having at least one water-permeable wall bounding a reservoir defined within the body. A drug formulation is disposed within the reservoir. The body has an elastic portion and at least one restraining plug closing off an opening of the body. The opening is in fluid communication with the reservoir, and the restraining plug contacts the elastic portion of the body and controls release of the drug from the device by the transient formation of one or more microchannels between the elastic portion of the body and the at least one restraining plug. The elastic portion may define an opening having an inner diameter, which is exceeded by the outer diameter of the restraining plug by at least 3 %.
Patent NZ-712210-A (NZ)
Title: Improved thymidine kinase gene
Inventor: LEVY JOHN
IPC: C12N5/16
Filed: 2014-03-14
Abstract: Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases (HSV-TK) are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. In particular, the mutations are located at positions 25, 26, 32, 33, 167 or 168 or a combination thereof. Also provided are gene therapeutic systems, including viral and retroviral particles.
Patent NZ-712340-A (NZ)
Title: Child-resistant zipper assemblies and packages utilizing the same
Inventor: VANLOOCKE CORY
IPC: B65D33/16
Filed: 2014-03-07
Abstract: Zippers provide a convenient way of opening and resealing a package. When the contents of a package may be harmful to children, such as laundry or dishwashing detergent, the convenience of zippers may possibly pose a risk of harm to children. Slider zippers make it even easier to open and reseal a zipped package. For potentially harmful contents, the increased convenience of slider zippers may then translate into increased risk of harm to children. Embodiments disclosed herein can provide slider zipper assemblies and packages utilizing them that may have decreased risk of harm to children, as compared with conventional zippers. In particular, the present invention relates to a zipper assembly configured to be child-resistant to opening, the zipper assembly comprising: first and second zipper tracks operably connected to a slider moveable between the first and second zipper tracks, wherein the inner surfaces of the first and second zipper tracks comprise interlocking members formed in and/or on the surfaces thereof and configured to interlock with each other, and wherein the outer surfaces of the first and second zipper tracks comprise movement resistive elements. The slider comprises a plow configured to engage between the inner surfaces of the first and second zipper tracks and configured to separate the interlocking members from each other when the slider is moved in a forward direction and thereby separate the first and second zipper tracks from each other. The slider further comprises a pair of clip arms configured to engage with the movement resistive elements on the outer surface of the first and second zipper tracks and resist movement of the slider in the forward direction while the clip arms are engaged with the movement resistive elements, wherein the clip arms comprise tabs configured to disengage the clip arms from the movement resistive elements upon applying sufficient pressure on the tabs, wherein disengagement of the clip arms from the movement resistive elements allows forward direction movement of the slider along the first and second zipper tracks.
Patent NZ-724236-A (NZ)
Title: Carbohydrate ligands that bind to igm antibodies against myelin-associated glycoprotein
Inventor: ERNST BEAT
IPC: G01N33/66
Filed: 2015-03-12
Abstract: The invention relates to carbohydrate ligands presenting the minimal Human Natural Killer-1 (HNK-1) epitope that bind to anti-MAG (myelin-associated glycoprotein) IgM antibodies, and their use in diagnosis as well as for the treatment of anti-MAG neuropathy. In particular, the invention relates to disaccharides of formula (I) and (II) wherein Z is optionally substituted phenyl, heteroaryl, arylcarbonyl, or heteroarylmethyl, and to therapeutically acceptable polymers comprising a multitude of substituents of formula (I) and/or formula (II), wherein Z is a bifunctional linker connecting the disaccharides to the polymer backbone.
Patent NZ-733888-A (NZ)
Title: System and method for purifying and preparing high-purity vanadium pentoxide powder
Inventor: ZHU QINGSHAN
IPC: C01G31/04
Filed: 2016-01-28
Abstract: The present invention provides a system and method for purifying and preparing vanadium pentoxide powder. Industrial grade vanadium pentoxide is converted to vanadium oxytrichloride by low temperature fluidizing chlorination, wherein chlorinating gas is preheated via heat exchange between fluidizing gas and chlorination flue gas, and an appropriate amount of air is added to enable a part of carbon powder to combust so as to achieve a balanced heat supply during the chlorination, thereby increasing the efficiency of chlorination and ensuring good selectivity in low temperature chlorination. The vanadium oxytrichloride is purified by rectification, and then subjected to fluidized gas phase ammonification, thereby obtaining ammonium metavanadate, and further obtaining a high-purity vanadium pentoxide powder product through fluidized calcination.
Patent NZ-734552-A (NZ)
Title: Motion vector derivation in video coding
Inventor: KARCZEWICZ MARTA
IPC: H04N19/44
Filed: 2016-03-25
Abstract: A decoder side motion vector derivation method includes determining a candidate motion vector for deriving motion information of a current block of video picture data, where the motion information indicates motion of the current block relative to reference video picture data, determining a derived motion vector for the current block based on the determined candidate motion vector by performing a motion search for a first set of reference data that corresponds to a second set of reference data outside of the current block, wherein the first set of reference data and the second set of reference data represent best match reference data, wherein the best match is based on a matching cost between the first set of reference data of the first reference video picture and the second set of reference data, wherein the matching cost comprises a magnitude of a difference between the derived motion vector and the candidate motion vector.
Patent NZ-735861-A (NZ)
Title: Wind power system
Inventor: BENAZZI RICCARDO
IPC: F03D1/02
Filed: 2015-03-05
Abstract: A wind power system, comprising at least one rotor (2), which controls at least one respective driven utility apparatus, and at least one stator (4), said at least one rotor being provided with a plurality of blades (5) hat have a substantially flat profile, and are arranged radially, said stator, which is arranged upstream of said at least one rotor, being provided with a tubular body (6), which is coaxial to the shaft (7) of said rotor nd coaxial to a substantially cylindrical outer enclosure (8), said tubular body being provided with a tapered end fairing and with respective curved vanes, wherein there is a forced path for air entering the system, aid path being defined by the inner walls of said enclosure, any two adjacent vanes and said tubular body, whereby said vanes have a first portion that is substantially parallel to the axis of said tubular body, and a curved second portion, in which the profile of said vanes arrives at an inclination with respect to the plane of rotation of said rotor which is between 130° and 140° degrees, such that the wind, after bein localized, is inserted between said vanes which force it to progressively change direction by approximately 45° degrees with respect to the axis of said rotor, and said blades of said rotor are in turn inclined, also with respect to the axis of said rotor, by an angle of approximately 45°, but in the opposite direction, such that the wind therefore will impact substantially perpendicular to and uniformly over all said blades, such that air entering said stator is directed toward the outer portion of said rotor onto said blades, thus maximizing the yield of the wind power system. The invention provides a wind power system that offers high yields but can operate with reduced windspeeds in areas having low levels of wind, and that is economic to manufacture, transport, install and maintain.
Patent NZ-740896-A (NZ)
Title: Hourglass pillow with internal baffle
Inventor: HOLBROOK RUSS
IPC: A47G9/10
Filed: 2016-07-11
Abstract: Conventional fiber or filled pillows may take a particular shape by virtue of the shape of the pillow shell. However, the fill in filled pillows will shift and may collect in areas such that the pillow loses the desired shape, such that the pillow may not provide the support or level of comfort desired. Accordingly, there is a need for a filled pillow that has a desired, non-rectangular shape. Desirably, such a pillow is configured such that in use, the fill remains in a desired area or volume of the pillow. The present invention in a preferred embodiment thus provides a pillow cover includes first and second panels joined to one another at front and rear edges to form upper and lower surfaces and side panels joined to the first and second panels at their respective peripheries. The side panels sides each have enlarged end portions with a thinning middle section to define an hourglass shape. The enlarged end portions having a major dimension. A baffle panel is joined to the first and second panels and extends between the side panels. The baffle panel has a height dimension less than the major dimension. The first and second panels, the side panels and the baffle panel define two continuous internal volumes. The baffle panel maintains the pillow in an hourglass shape. The side panels are symmetrical front to back. A filled pillow having an hourglass shape is also disclosed.
Patent NZ-754900-A (NZ)
Title: Systems and methods for removing volatile compounds from water-storage tanks
Inventor: GIGUERE ROBIN
IPC: C02F1/20
Filed: 2017-12-29
Abstract: A system for reducing an amount of volatile organic compounds which includes: a water-storage tank having a tank containing water, a roof positioned over the tank, and a headspace region formed between the roof and a surface of the water contained in the tank; an air exchange system positioned at least partially in the headspace region that is configured to exchange air exterior to the tank with air inside the tank; and a water conveyance device located at least partially in the water of the water-storage tank and which is configured to convey water in a manner that produces a surface flow velocity. A method reducing an amount of volatile organic compounds is also included.
Patent NZ-773792-A (NZ)
Title: Respiratory pressure therapy device
Inventor: SHADIE TIMOTHY NICHOLAS
IPC: A61M16/00
Filed: 2016-03-14
Abstract: A system for generating breathable gas for the treatment of a respiratory disorder, comprising: a respiratory pressure therapy (RPT) device configured to generate a flow of breathable gas at a pressure above ambient, and an external battery comprising a facia and one or more battery cells, wherein the facia is configured to removably connect to the RPT device, wherein the RPT device and the external battery comprise guiding members to facilitate alignment, connection and disconnection, and wherein the facia comprises an air inlet, and/or an air outlet, structured and or arranged such that when the external battery is connected to the RPT device the air inlet and/or air outlet extend an air path of the RPT device.
Patent NZ-777241-A (NZ)
Title: Electronic vapour provision system
Inventor: FRASER RORY
IPC: A24F47/00
Filed: 2016-06-15
Abstract: An electronic vapour provision system comprises a control unit and a cartridge configured to engage with and disengage from one another substantially along said longitudinal axis. The cartridge includes a reservoir of liquid to be vaporised, and the control unit includes a battery and a tube portion disposed along said longitudinal axis. The tube portion comprises an inner wall and an outer wall defining an annular space around the longitudinal axis. The system further comprises an induction heating assembly comprising a drive coil and a heater element. The heater element is located in the cartridge for vaporising the liquid. The cartridge is configured to feed liquid from the reservoir onto the heater element for vaporisation. The drive coil is located in the annular space of the tube portion of the control unit, between the inner wall and the outer wall of the tube portion, and disposed about said longitudinal axis. The cartridge is located at least partly within the inner wall of the tube portion when engaged with the control unit, such that the heater element is within the drive coil.
Patent NZ-790834-A (NZ)
Title: Inhibition of crystal growth of roflumilast
Inventor: OSBORNE DAVID W
IPC: A61K9/00
Filed: 2018-06-04
Abstract: Roflumilast crystals have been shown to increase in size during storage. The size of the roflumilast crystals can affect the bioavailability and efficacy of a pharmaceutical composition. The growth of roflumilast crystals can be inhibited during storage by including hexylene glycol in the composition. The resulting composition has improved bioavailability and efficacy and can be used to inhibit phosphodiesterase 4 in patient in need of such treatment.
Patent PT-100131-A (PT)
IPC: D01G/
Filed: 1992-02-18
Abstract: PCT No. PCT/DE92/00119 Sec. 371 Date Aug. 20, 1993 Sec. 102(e) Date Aug. 20, 1993 PCT Filed Aug. 20, 1993 PCT Pub. No. WO92/14872 PCT Pub. Date Sep. 3, 1992.A device for opening flocculent fibrous materials, including a housing and a supply connection pipe having an end extending into a lower portion of the housing for introducing into the housing a negative pressure transport air current conveying fiber flocks. A hollow cylinder is provided that has one end connected to the end of the supply connection pipe, an open end opposite to the one end, and a diameter larger than a diameter of the end of the supply connection pipe. The hollow cylinder forms an annular chamber within the housing. The device further includes a discharge connection pipe connectable to the housing for discharging the fibrous material. The housing, supply connection pipe, hollow cylinder and discharge connection pipe collectively define a pneumatic conveying path for the fibrous material. Additionally provided is a drivable opening disc disposed within the housing and positioned at a distance from and parallel to the open end of the hollow cylinder to extend across the open end. The disc includes a plurality of pointed spikes each projecting towards the hollow cylinder for processing material as it is conveyed along the pneumatic conveying path.
Patent PT-104126-A (PT)
Title: Equipamento e método para testar resistência dos geossintéticos à termo-oxidação
Inventor: ALMEIDA PAULO JOAQUIM FERREIRA
IPC: G01N3/00
Filed: 2008-07-07
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UM EQUIPAMENTO E UM MÉTODO DESENVOLVIDOS PARA TESTAR A RESISTÊNCIA DOS GEOSSINTÉTICOS À TERMO-OXIDAÇÃO. O EQUIPAMENTO DESENVOLVIDO É CONSTITUÍDO POR UM AUTOCLAVE (16) (ONDE OS GEOSSINTÉTICOS SÃO EXPOSTOS AO ENSAIO DE TERMO-OXIDAÇÃO) E POR UMA UNIDADE DE CONTROLO (17) (QUE ALIMENTA ELECTRICAMENTE O AUTOCLAVE (16) E PERMITE MONITORIZAR E CONTROLAR ALGUNS PARÂMETROS EXPERIMENTAIS DO ENSAIO). NO NOVO MÉTODO, A TERMO-OXIDAÇÃO DOS GEOSSINTÉTICOS OCORRE NUM MEIO LÍQUIDO, A UMA TEMPERATURA E A UMA PRESSÃO ELEVADAS. OS MATERIAIS SÃO IMERSOS NUMA SOLUÇÃO DE PERÓXIDO DE HIDROGÉNIO QUE, POR DECOMPOSIÇÃO, LIBERTA OXIGÉNIO, ORIGINANDO UM AUMENTO DA PRESSÃO NO INTERIOR DO AUTOCLAVE (16) (EQUIPAMENTO ESTANQUE). O NOVO MÉTODO E EQUIPAMENTO SÃO UM COMPLEMENTO E/OU ALTERNATIVA AOS MÉTODOS JÁ EXISTENTES PARA TESTAR A RESISTÊNCIA DOS GEOSSINTÉTICOS À TERMO-OXIDAÇÃO.
Patent RO-85383-A (RO)
Inventor: BALZER DIETER
IPC: E21B43/22
Filed: 1981-09-09
Abstract: A process for recovering extensively emulsion-free oil from a subterranean deposit of medium or high salinity comprises forcing into an injection well a 1-20% strength solution or dispersion in formation water of a carboxymethylated ethoxylate tenside of the formula: R-(OCH2CH2)n-OCH2-COOM wherein R is a linear or branched aliphatic residue of 4-20 carbon atoms or a mono- or dialkylaromatic residue of 1-14 carbon atoms in the alkyl group, n is 3-30, and M is an alkali or alkaline earth metal ion or ammonium, and wherein the degree of carboxymethylation is incomplete, wherein the tenside is selected so that the phase inversion temperature of the system: crude oil/formation water/tenside/optional additives, lies 0 DEG -10 DEG C. above the deposit temperature.
Patent RU-94002713-A (RU)
Inventor: SHKOL NIKOVA M A
IPC: A61K31/525
Filed: 1994-02-04
Abstract: FIELD: medicine. SUBSTANCE: method involves determining sudden death risk level and administering a proper treatment course. EFFECT: enhanced effectiveness of the method.
Patent RU-94014952-A (RU)
Inventor: DANILENKO A I
IPC: G01S5/04
Filed: 1994-04-21
Abstract: FIELD: radar systems and radio navigation; multi-position radar systems consisting of several radio direction finders - passive triangulation systems which may be used in shipboard control systems whose navigational radar systems are used as source of signal for taking bearings. SUBSTANCE: for identification of source of angular information obtained by radio direction finders, use is made of additional information on time of passage of major lobe of directional pattern of revolving radar antennas through points of location of radio direction finders. To this end, system is provided with signal identification unit which is common for all radio direction finders; each position of radio direction finders is provided with reading command forming unit, signal arrival time recording unit and communication channel for transmitting the data on signal arrival time; output of reading command forming unit is connected with radio direction finder and its communication channel and with signal arrival time recording unit and its communication channel; outputs of all communication N-channels for transmitting the data on angular position and outputs of all communication N-channels for transmitting the data on signal arrival time are connected with 2N-inputs of signal identification unit which is common for all positions; N-inputs of identification unit are connected to N-inputs of coordinate determination unit. EFFECT: enhanced reliability of representation of situation.
Patent RU-94024226-A (RU)
Inventor: GRUZDEV V N
IPC: F23R3/34
Filed: 1994-06-29
Abstract: FIELD: manufacture of aircraft engines; heat-power engineering; combustion chambers of gas-turbine engines; various thermal gas generators feeding hot combustion products to working volume; surface gas-turbine engines used in gas-transfer systems or in peak power stations. SUBSTANCE: required amount of combustible gas is fed in small jets distributed over cross-section of combustion chamber. Rate of gas supply always exceeds rate of incoming flow of air and ratio of these rates is preset depending on degree of gas preheating which is determined by coefficient of air excess. Reliable transfer of flame is ensured by proper relationship of rates of gas supply and incoming flow of air, as well as by proper diameter of jets. EFFECT: reduction of flame length, increased degree of complete combustion and reduction of concentration of nitric oxides in combustion products.
Patent RU-94028624-A (RU)
Inventor: POLEVSKIJ V I
IPC: H02K41/06
Filed: 1994-07-28
Abstract: FIELD: electrical engineering. SUBSTANCE: invention can be used in transportation means with translational or rotary- translational movement of element. Motor has inductor 1 with winding 2, flux concentrators 7, mobile platform 6 to move object, rotor 4 with V-shaped bracket 9 put into it, bearing 10, axle 11, magnetic core 8 having shape of segment with friction spacers 12 on edges. Rotor is coupled to side wall of mobile platform which can deviate till friction spacer engages inner surface of rotor manufactured in the form of conductive hollow cylinder. EFFECT: provision for braking when power supply source is disconnected. 1 dwg
Patent RU-94030565-A (RU)
Inventor: KOPKOV G A
IPC: F16K17/04
Filed: 1994-08-17
Abstract: FIELD: automatic control systems of power generating plants; liquid propellant rocket engines; hydraulic automatics. SUBSTANCE: valve has body with spring-loaded plunger closing passage area of body. Under-plunger space communicates with low pressure space through return channel. A channel is made in plunger bottom. Surface of channel is of special shape. Installed in under-plunger space is rod kinematically coupled with control shaft of control system. EFFECT: enlarged operating capabilities.
Patent RU-94033476-A (RU)
Inventor: AL BERTO DEL B JANKO
IPC: C10G1/04
Filed: 1994-09-16
Abstract: FIELD: oil and gas production. SUBSTANCE: composition for dissolving asphaltene deposits occurring in oil wells contains saturated hydrocarbon, alkylbenzenes, and polyaromatics. A method for dissolution is also proposed. EFFECT: facilitated oil extraction. 7 cl, 1 dwg