baber/WOPTO huggingface dataset:
Patent IL-81420-A0 (IL)
Title: Phenolic thioethers and pharmaceutical compositions containing them
IPC: C07C323/52
Filed: 1987-01-29
Abstract: The compounds of the present invention comprise substituted phenolic thioethers represented by the formula:   <IMAGE> (I)  wherein: R1 and R2 are the same or different and independently represent tert-alkyl or phenyl; A represents methylene or methylene substituted by alkyl, dialkyl or hydroxy, provided that when A includes hydroxymethylene, the hydroxymethylene group is not adjacent to a heteroatom; B represents sulfur, sulfoxide, sulfone, oxygen, -NH- or nitrogen substituted by alkyl, phenyl, benzyl, substituted phenyl or substituted benzyl; C represents methylene or methylene substituted by alkyl; R3 represents CO2H, CO2-alkyl or a tetrazole group; m is 0 or 1, n is 2, 3 or 4 and p is 1, 2 or 3; and the pharmaceutically acceptable salts thereof. The compounds of the present invention are specific inhibitors of 5-lipoxygenase and, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.
Patent IL-85388-A0 (IL)
Title: Pharmaceutical compositions containing oxoquinazoline derivatives for the treatment of hyperuricaemia
IPC: C07D487/04
Filed: 1988-02-10
Abstract: Oxoquinazoline derivatives of formulae    <IMAGE>  (I)  and   <IMAGE> (II)  (the symbols are defined in the specification) are well-tolerated drugs for treating hyperuricaemia.
Patent IL-92052-A0 (IL)
Title: 4-substituted anthracyclinones and anthracycline glycosides and the process for preparing them
IPC: B01J31/22
Filed: 1989-10-19
Abstract: 4-substituted anthracyclinones of formula (I): <CHEM> wherein R represents a straight or branched alkyl, alkenyl or alkynyl group of up to 16 carbon atoms optionally substituted by (a) an aryl group which is unsubstituted or substituted by an inert group such as an alkyl, alkoxy or nitro group; (b) an alkoxy group; (c) a trialkylsilyl group, (d) an ester group or (e) an amido group, are intermediates in the preparation of antitumor anthracycline glycosides of formula (IX): <CHEM> wherein R is as defined above and R1 is a hydrogen atom or a hydroxy group, and pharmaceutically acceptable salts thereof.
Patent AU-PN436995-A0 (AU)
Title: Method for the production of thrombin
IPC: C12N9/74
Filed: 1995-07-24
Abstract: A method for the preparation of thrombin from a prothrombin-containing material is characterised in that the prothrombin-containing material is an activated prothrombin complex concentrate ActPCC fraction, which is contacted with divalent cations to convert the prothrombin to thrombin.
Patent AU-PQ582900-A0 (AU)
Title: Printed media production
IPC: G06Q30/02
Filed: 2000-02-24
Abstract: A method of estimating a position of nib of a pen relative to an optical sensor removably mounted on the pen. The optical sensor captures at least two images of a coded surface when the nib contacts the coded surface. The images are captured with the nib at a same position on the coded surface and the pen at different orientations relative to the coded surface. From a perspective distortion of the coded surface in each image, an estimated rotation and viewing distance for each image are estimated, and from the estimated rotations and viewing distances, the position of the nib relative to the optical sensor is estimated.
Patent FI-20040217-A0 (FI)
Inventor: NAATTI ILKKA
IPC: B65H19/22
Filed: 2004-02-12
Abstract: The invention relates to a method and an apparatus in reeling up, in which a paper web or the like (W) is reeled around a center-driven reel spool ( 5 ), which is transferred from the primary reeling to the secondary reeling, in which reeling the reel spool ( 5 ) is transferred in accordance with the growth of the reel by means of a transfer device ( 7 ) at least at some stage of the reeling and the web is brought at said stage from below the reel spool ( 5 ) via a reeling nip (N 1 ) formed by the reel spool ( 5 ) and a loop ( 1 ) of an endless supporting member. According to the invention the web (W) is guided around the reel spool ( 5 ) during the reeling via an auxiliary nip (N 2 ) formed by means of the reel spool ( 5 ) and the roll ( 10, 10' ).
Patent FI-20055170-A0 (FI)
Inventor: AUTIO JUHA
IPC: B27L7/00
Filed: 2005-04-14
Abstract: A machine for splitting wood pieces comprises a splitting space (7) for the placement of a wood piece, a splitting head (3) arranged to move back and forth in the splitting space (7) and connected to an actuator, which is driven by pressurized medium and arranged to produce said movement, and a splitting blade (8) placed on the extension of the motion path of the splitting head (3) for splitting the wood piece (K). The splitting head (3) is connected to two actuators (1, 2) in parallel, and the working pressure of the pressurized medium is arranged to be coupled selectively to the actuators so that in the first coupling position, the actuators (1, 2) provide a higher total thrust force and a lower speed than in the second coupling position.
Patent IL-108067-A0 (IL)
Title: Biphenyl derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
IPC: C07D233/88
Filed: 1993-12-17
Abstract: Compounds of formula (I) : <CHEM>  [wherein: A represents a group (IIa), (IIb) or (IIc) : <CHEM>   <CHEM> R<1> is alkyl, alkenyl, cycloalkyl or a group of formula R<4>-Y-R<5>-, where: R<4> is hydrogen, alkyl, or cycloalkyl, R<5> is a single bond or alkylene, and Y is oxygen, sulphur or imino group; R<2> is hydrogen, halogen, Optionally substituted alkyl, optionally substituted alkenyl, optionally substituted cycloalkyl, hydroxy, amino, alkylamino, dialkylamino, formyl, alkylcarbonyl, alkoxy, alkylthio, cyano or nitro; R<3> is hydrogen, alkyl, carboxy, protected carboxy, carbamoyl or tetrazol-5-yl; X is of formula -CH=, -N= or -C(COOR<6>)=, where R<6> is hydrogen or a carboxy-protecting group; Z is a single bond, alkylene or vinylene; and B is carboxy, protected carboxy or tetrazol-5-yl]; and pharmaceutically acceptable salts and esters thereof have the ability to inhibit the action of angiotensin II and thus can be used for the treatment and prophylaxis of hypertension and cardiac iseases.
Patent IL-112081-A0 (IL)
Title: Tetrahydrofuran antifungals
IPC: C07D405/14
Filed: 1994-12-20
Abstract: A compound represented by formula (I) wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy moieties, an ether or ester (e.g., a polyestherester or phosphate ester) thereof a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.
Patent IL-115499-A0 (IL)
Title: Preparation of 2,6-disubstituted benzenesulfonate and certain derivatives thereof
IPC: C07C319/14
Filed: 1995-10-02
Abstract: A method is provided for making a substituted benzene compound which comprises: reacting a 2-substituted benzenesulfonate, or the 2-substituted benzenesulfonate further substituted in the 3,4 or 5-position, with a lithium compound to form an intermediate; and reacting the intermediate with an electrophile to form a 2,6-disubstituted benzenesulfonate or a 2,6-disubstituted benzenesulfonate further substituted in the 3,4 or 5-position.
Patent IL-127275-A0 (IL)
Title: Process to eliminate hemoglobin errors when analyzing medical samples
IPC: G01N21/31
Filed: 1997-05-30
Abstract: The present invention relates to a process for determining an analyte in a sample containing free haemoglobin by optical bichromatic measurement for a main and a secondary measuring wave length. A secondary measuring wave length of above 475 nm is used containing absorption bands of haemoglobin.
Patent IL-128163-A0 (IL)
Title: Polymer-lipid microencapsulated gases for use as imaging agents
IPC: A61K49/22
Filed: 1997-02-27
Abstract: It has been discovered that the incorporation of gases, especially fluorinated gases such as perfluorocarbons, into microparticles formed from the combination of a natural or synthetic polymer and lipid have significantly enhanced echogenicity as compared with microparticles not including the lipid. Compounds other than lipids which are hydrophobic and limit the penetration and/or uptake of water into the microparticles can also be incorporated into the microparticles to enhance echogenicity. In the preferred embodiment, the polymers are synthetic biodegradable polymers. The microparticles are manufactured with a diameter suitable for the targeted tissue to be imaged, for example, with a diameter of between 0.5 and 8 microns for intravascular administration, and a diameter of between 0.5 and 5 mm for oral administration for imaging of the gastrointestinal tract or other lumens. Preferred polymers are polyhydroxy acids such as polylactic acid-co-glycolic acid, most preferably conjugated to polyethylene glycol or other materials inhibiting uptake by the reticuloendothelial system (RES). The most preferred lipids are phospholipids, preferably dipalmitoylphosphatidylcholine (DPPC), distearoylphosphatidylcholine (DSPC), diarachidoylphosphatidylcholine (DAPC), dibehenoylphosphatidylcholine (DBPC), ditricosanoylphosphatidylcholine, dilignoceroylphatidylcholine (DLPC), incorporated at a ratio of between 0.01-30 (w lipid/w polymer), most preferably between 0.1-10 (w lipid/w polymer). Microparticles for imaging using other detectable agents can be similarly manufactured.
Patent IL-128960-A0 (IL)
Title: Therapy for alpha-galactosidase a deficiency
IPC: A61P35/00
Filed: 1997-09-12
Abstract: The present invention provides a process for purifying human ±-galactosidase A (±-gal A) from a sample, wherein the process comprises a first chromatography step wherein the sample is passed over a hydrophobic interaction resin.
Patent IL-130164-A0 (IL)
Title: Mammalian chemokines
IPC: A61K38/00
Filed: 1997-11-26
Abstract: Novel CC chemokines from human, reagents related thereto including purified proteins, specific antibodies and nucleic acids encoding these chemokines are provided. Also provided are methods of making and using said reagents and diagnostic kits.     00000
Patent IL-130495-A0 (IL)
Title: Condiment shaker
IPC: B65D47/06
Filed: 1999-06-16
Abstract: A condiment shaker (10) includes a wiper unit (14) with multiple wiping blades (34) releasably thread mounted to the upper end of a container (12) and in turn overlaid by a removable perforated sprinkler top (16) which rotates relative to the joined container and wiper unit. The wiping blades (34) extend radially outward from a solid central hub (36) and wipingly engage the perforated top panel (50) of the sprinkler top. <IMAGE>
Patent IL-136453-A0 (IL)
Title: Topical zinc compositions and methods utilizing the same
IPC: A61K31/198
Filed: 2000-05-30
Abstract: Compositions including zinc compounds and select amino acids in a carrier base, and methods of skin treatment with such compositions, are described. The compositions are useful for healing skin and minimizing the irritation incurred from contact with the zinc compound without loss of zinc availability during absorption into the integument.
Patent IL-137891-A0 (IL)
Title: Disinfecting composition
IPC: A61K31/19
Filed: 1999-03-16
Abstract: A disinfecting composition includes about 0.01 to 2% by weight 2,4-dichlorobenzyl alcohol, about 0.1 to 10% by weight of glycerylmonolaurate, and about 95 to 99.5 % by weight vehicle such as a mixture of water and alcohol.
Patent IL-144617-A0 (IL)
Title: Adhesives
IPC: C09J/
Filed: 2000-01-31
Abstract: An adhesive material is suitable as a bioadhesive and comprises an adhesive polymer and a plasticizier thereof, wherein the adhesive is cross-linked, characterized in that the adhesive comprises ketone groups cross-linked by a polyamine cross-linking agent. Such adhesives have good cohesion and low dermal irritation.</PTEXT>
Patent IL-145524-A0 (IL)
Title: Formulation comprising testosterone undecanoate and castor oil
IPC: A61K31/568
Filed: 2000-03-27
Abstract: Disclosed is a pharmaceutical formulation in the form of a capsule for oral administration comprising testosterone undecanoate as an active ingredient dissolved in a pharmaceutically acceptable liquid carrier, characterised in that the liquid carrier comprises at least 50 % by weight of castor oil. The choice of castor oil as the liquid carrier, in conjunction with the choice of testosterone undecanoate as the androgen, makes for a solution which can comprise about 200-250 mg/ml of TU. This is a novel achievement for any orally administerable solution of testosterone. The solution may also contain a lipophilic surfactant such as lauroglycol.
Patent IL-145644-A0 (IL)
Title: Vortex generating means within a beer dispenser
IPC: B67D1/14
Filed: 2000-03-27
Abstract: A beverage dispensing apparatus being formed so as in use to provide a vortex motion in the mass of beverage flowing through the apparatus. In the vortexial flow, a low pressure area is produced at the center of the vortex so that the pressure in that region falls below equilibrium pressure and thus results in gas separating out from the liquid beverage. Since the gas breakout is achieved without the need for a flow restrictor, the pressure drop associated with these devices does not occur. Consequently, the beverage may enter the apparatus at a lower pressure. Moreover it has been found that a high quality head is formed on the draught beverage dispensed from the apparatus of the invention.
Patent IL-152731-A0 (IL)
Title: Adjustable gastroplasty p??g comprising a grip tab
IPC: A61F5/00
Filed: 2001-05-11
Abstract: The invention relates to a gastroplasty ring formed by a flexible band (2) which comprises a first end part (5) and a second end part (6) and which is intended to be closed around the stomach toward its two end parts by a closure system in order to reduce the diameter of the opening of the stoma by forming a loop, the band comprising an adjustable-volume annular compression chamber (3) connected, at the first end part, by an adjusting catheter (7) to a device for adjusting the internal pressure of said chamber, so as to adjust its diametral expansion, the ring comprising at least one grab tab (11, 12, 13) which projects toward the outside of the loop to make it easier for the two end parts to be brought together and parted. Gastric implant for treating obesity.
Patent IL-155201-A0 (IL)
Title: Preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol
IPC: C07C209/48
Filed: 2001-10-18
Abstract: A process for the preparation of 1,4-bis(hydroxymethyl)-2,3,5,6-tetrafluorobenzene comprising fluorinating 2,3,5,6-tetrachloroterephthalonitrile to obtain 2,3,5,6-tetrafluoroterephthalonitrile, hydrogenating 2,3,5,6-tetrafluoroterephthalonitrile to give 1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene and converting 1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene to 1,4-bis(hydroxymethyl)-2,3,5,6-tetrafluorobenzene.
Patent IL-170749-A0 (IL)
Title: Pharmaceutical compositions containing a cholesteryl ester transfer protein inhibitor
IPC: A61K31/16
Filed: 2005-09-08
Abstract: The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CEPT) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor.
Patent IL-183914-A0 (IL)
Title: Method for informing multiple mobile terminals of an emergency event
IPC: H04W4/90
Filed: 2007-06-14
Abstract: A method, devices, a system, and computer programs for informing multiple mobile terminals (UE10-90) of an emergency event are disclosed. The method comprises the steps of receiving (S300) emergency information associated with the emergency event, establishing (S400) an emergency multimedia capable distribution bearer for a delivery of an emergency service associated with the received emergency information, the emergency multimedia capable distribution bearer being associated with an emergency priority indicator indicating a higher priority for the emergency multimedia capable distribution bearer compared to further communication being not associated with the emergency priority indicator, and delivering (S600) the emergency service via the emergency multimedia capable distribution bearer to the multiple mobile terminals (UE10-90).
Patent IL-184338-A0 (IL)
Title: Process for producing (z)-1-phenyl-1-(n,n-diethylaminocarbonyl)-2-phthalimidomethylcyclopropane
Filed: 2007-07-01
Abstract: The present invention provides a process for producing (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-phthalimidometh ylcyclopropane, which includes reacting (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-hydroxymethylcy clopropane with an orthoester and a brønsted acid, and reacting the reaction product with a phthalimidating agent; and a process for producing (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-aminomethylcycl opropane hydrochloride through the above process.
Patent IL-185147-A0 (IL)
Title: Replication-deficient rna viruses as vaccines
Filed: 2007-08-09
Abstract: Recombinant negative-strand RNA virus (I) comprises a viral genome with a mutation in the N, L or P gene that results in loss of replication capability without loss of transcription capability. Independent claims are also included for: (1) nucleocapsid (II) of (I); (2) genome (III) of (I); (3) DNA molecule (IV) coding for the genome or antigenome of (I); (4) cell (V) containing (I), (III) or (IV); (5) producing (I) by providing a cell transfected with a DNA molecule coding for (I) and optionally a heterologous gene product, and culturing the cell under conditions suitable for transcription of the DNA molecule; (6) multiplying (I) by providing a cell infected with (I) and culturing the cell under conditions suitable for multiplication of (I); (7) pharmacuetical composition comprising (I), (II) or (III); (8) use of a cell (VI) that stably expresses the N, L or P protein of a negative-strand RNA virus in a constitutive or inducible manner for producing or multiplying (I) (II) or (III). ACTIVITY : Virucide. MECHANISM OF ACTION : Vaccine; Ribozyme; Antisense oligonucleotide inhibitor; RNAi; RNA interference.
Patent IL-187568-A0 (IL)
Title: Cutting machine to cut rolls or logs of web material and relative method
Filed: 2007-11-22
Abstract: The cutting machine includes pairs of coaxial blades to simultaneously cut two rolls for each cutting cycle.
Patent IL-188652-A0 (IL)
Title: Bistatic radioelectric device for producing an intrusion detecting barrier
Filed: 2008-01-08
Abstract: The barrier has a principal emission unit with directive emission antenna (21) and non directive emission antenna (22) to emit a wave constituting the barrier across the antennae. A reception unit (14) compares the relative level of echo received from wave emitted by the antenna (21) and echo from waves emitted by the antenna (22). The comparison results identify the echo from a wave emitted in the direction of a secondary lobe (18) of the directive emission antenna.
Patent IL-194992-A0 (IL)
Title: The use of anti-histaminics for acute reduction of elevated intracranial pressure
IPC: C07D471/00
Filed: 2008-10-30
Abstract: The invention concerns the use of an H1- and/or H2-histamine receptor antagonist for the reduction of intracranial pressure (ICP), in particular for the prevention and treatment of elevated intracranial pressure and/or secondary ischaemia, in particular caused by brain injury, more in particular caused by traumatic (TBI) and non-traumatic brain injury. In particular, the histamine antagonist is selected from the group of acrivastine, alimemazine, antazoline, astemizole, azatadine, azelastine, brompheniramine, buclizine, carbinoxamine, carebastine, cetirizine, chlorcyclizine, chlorpheniramine, cinnarizine, clemastine, clemizole, clocinizine, clonidine, cyclizine, cyproheptadine, descarboethoxyloratidine, dexchlorpheniramine, dimenhydrinate, dimethindene, dimethothiazine, diphenhydramine, diphenylpyraline, doxylamine, ebastine, efletirizine, epinastine, fexofenadine, hydroxyzine, ketotifen, levocabastine, loratidine, meclizine, mequitazine, methdilazine, mianserin, mizolastine, niaprazine, noberastine, norastemizole, oxatomide, oxomemazine, phenbenzamine, pheniramine, picumast, promethazine, pyrilamine, temelastine, terfenadine, trimeprazine, tripelennamine, triprolidine, ranitidine, cimetidine, famotidine, nizatidine, tiotidine, zolantidine, ritanserine, and derivatives thereof and mixtures of any two or more of the foregoing.
Patent IL-196150-A0 (IL)
Title: Variable control channel for a wireless communication system
IPC: H04W72/06
Filed: 2008-12-23
Abstract: Techniques for sending control information on a variable control channel are described. Different structures for mapping control information to control channel resources may be used depending on various factors such as operating configuration, the available resources for the control channel, the type(s) of control information being sent, the amount of control information being sent for each type, whether or not data is being sent, etc. In one design, at least one type of control information being sent may be determined and may comprise channel quality indicator (CQI) information, acknowledgement (ACK) information, and/or other types of control information. A structure of the control channel may be determined based on operating configuration (e.g., system configuration such as asymmetry of downlink and uplink allocations) and/or other factors. The at least one type of control information may be mapped to the resources for the control channel based on the structure.
Patent IL-211788-A0 (IL)
Title: Wnt-1 induced secreted polypeptides: wisp-1', -2 and -3
IPC: C12N15/09
Filed: 2011-03-17
Abstract: Wnt-l-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
Patent RO-130893-A0 (RO)
Title: Microbial biopreparation with preservative effect upon forage plants, consisting of lactobacillus brevis
Inventor: ABRAHAM BEATA
IPC: C12N1/20
Filed: 2015-05-18
Abstract: The invention relates to a microbial biopreparation with preservative effect upon forage plants. According to the invention, the biopreparation consists of a strain of Lactobacillus brevis KLII.1. deposited under the number NCAIM (P) 8001435, which is a native lactic bacterium isolated from cabbage pickle obtained by spontaneous fermentation, meant to be used for ensilaging plants from mountain meadows, with beneficial effects upon forage preservation.
Patent RO-134065-A0 (RO)
Title: Platform and method for connecting a blockchain engine
Inventor: IFTEMI ALIN-DANIEL
IPC: H04L9/06
Filed: 2019-08-14
Abstract: The invention relates to a platform and to a method for connecting a blockchain engine to a traditional database. According to the invention, the platform is implemented in the form of a network of nodes which is divided into at least two subnets: a security subnet and a data subnet, all nodes in the security subnet containing information relating to user security keys, operating licenses, access policies, as well as other information relating to the mechanism of licensing, authentication and authorization of users accessing the platform, and the nodes in at least one data subnet comprise a software component which uses a computer network, an API communication interface which allows the interaction with the computer network and the taking over the of the information to be stored in a storage system, a GraphQL interface for data query, a data processing engine, a blockchain engine, a connection interface between the data processing engine and the blockchain engine, and a database.