baber/WOPTO huggingface dataset:
Patent DO-P2003000788-A (DO)
Title: Compuestos de indazol y composiciones farmaceuticas para inhibir proteinquinasas, y procedimientos para su uso
Inventor: PALMER CYNTHIA LOUISE
Filed: 2003-12-10
Abstract: Se describen compuestos de indazol que modulan y/o inhiben las enfermedades oftalmicas y la actividad de ciertas proteinquinasas. Estos compuestos y composiciones farmaceuticas que los contienen son capaces de mediar la transducción de la sepal de tirosina quinasa y por lo tanto modular y/o inhibir la proliferacion celular no deseada. La invención tambien se refiere al use terapeutico o profilactico de las composiciones farmaceuticas que contienen dichos compuestos, y a procedimientos de tratamiento de enfermedades oftalmicas y cancer y otros estados de enfermedad asociados con angiogenesis y/o proliferacion celular no deseadas, tales como retinopatia diabetica, glaucoma neovascular, artritis reumatoide y psoriasis, mediante la administracion de cantidades eficaces de dichos compuestos.
Patent DO-P2023000122-A (DO)
Title: Nanosistemas basados en nanocompositos y extractos naturales
Inventor: ALEJANDRO PEREZ LARIOS
IPC: A01N59/16
Filed: 2023-06-14
Abstract: La presente invención se refiere a nanosistemas que comprenden nanocompositos para la adsorción o soporte de extractos naturales, procesos para su preparación y formulaciones que los contienen así como a un nanomaterial que adsorbe uno o más aceites esenciales en su superficie. En especial la invención tiene como uno de sus objetos la encapsulación de extractos naturales, como por ejemplo aceites esenciales y/o compuestos bioactivos puros naturales y opcionalmente compuestos terpeneoides, sesquiterpenoides, diterpenoides, sesterpenoides, triterpenoides, carotenoides, resinoides, ácidos y polisacáridos complementarios, vitaminas y otros compuestos orgánicos en materiales mesoporosos, para su aplicación en diferentes industrias como lo es la alimentaria, agrícola, veterinaria, acuicultura, farmacéutica, cosmética, medicina, limpieza, sanitización, desinfección.
Patent EC-SP10010291-A (EC)
Title: Derivados bicíclicos para usar en el tratamiento de afecciones asociadas con el receptor de andrógeno
Inventor: BRADBURY ROBERT HUGH
IPC: A61K31/4196
Filed: 2010-06-21
Abstract: La invención se refiere a los compuestos bicíclicos de Fórmula (I), donde los números enteros X1, X2, X3, el Anillo A, R4, R5 y m son como los definidos en la descripción. La presente invención también se relaciona con procesos para la preparación de tales compuestos, composiciones farmacéuticas que los contienen y su uso en la fabricación de un medicamento para su uso en la prevención o tratamiento de afecciones asociadas con el receptor de andrógeno.
Patent GB-189700006-A (GB)
Title: An Improvement in Ascension Pipes Used in the Manufacture of Coal Gas.
Inventor: MEEK THOMAS JAMES
Filed: 1897-01-01
Granted: 1897-05-15
Abstract: 6. Meek, T. J., Davison, H., and Southam, J. Jan. 1. Distilling tar.-Ascension pipes such as are used in tar distilleries &c. are provided near their lower ends with an opening and branch pipe A, fitted with a door D, to facilitate cleaning &c. The door D is pivoted on one side in a bracket C, and furnished at the other with a lever I which drops into a catch G.
Patent GB-189701860-A (GB)
Title: Improvements in or connected with Incandescent Gas Light Burners.
Inventor: NAGEL AUGUST
Filed: 1897-01-23
Granted: 1897-04-03
Abstract: 1 8 6 0. Nagel, A. Jan. 23. Incandescent gas burners.-Air under pressure is supplied through the pipe d, and the usual chimney may be dispensed with. The mixing-tube b of the burner is made longer than usual, and is provided with two gauzes g,f to prevent noise and to steady the flame. The pure nickel rod h carrying the mantle may be adjusted by means of the screw i.
Patent GB-189704676-A (GB)
Title: Improvements in Gas-holder and Liquid Reservoirs.
Inventor: KELTING RUDOLF
Filed: 1897-02-20
Granted: 1897-04-17
Abstract: 4676. Kelting, R. Feb. 20. Gas holders.-A sheet - metal water tank a for gas holders &c. is enclosed towards its lower end by a casing b filled with water so as to reduce the necessary thickness of the inner wall. The casing b may be further enclosed in a similar manner.
Patent GB-189708741-A (GB)
Title: Improvements in Hair Brushes.
Inventor: GLOVER GEORGE WILLIAM
Filed: 1897-04-06
Granted: 1897-05-22
Abstract: 8741. Glover, G. W. April 6. Hair brushes. - The stock of military hair brushes is provided with a recess closed by .a sliding lid 7 held in its closed position flush with the back by a catch 11. A comb 4, and if desired a mirror 13, are placed in the recess.
Patent GB-189709056-A (GB)
Title: Improvements in the Method of and Means for "Mercerising" Vegetable Fibres, Fabrics, and the like.
Inventor: CREPY EUGENE
Filed: 1897-04-09
Granted: 1898-02-26
Abstract: 9056. CrÚpy, E. April 9. Yarns, mercerizing. - The material is stretched while being treated with the mercerizing-solution. The Figure shows hanks of yarn stretched over a pair of rotating rollers a, a<1>, of which one is adjustable by means of screws &c. The rollers are mounted in the sides of a tank or trough b, and the mercerizing-solution flows from a tank d on to the material and escapes from the trough b into one side of a double sink f and may be collected. When the mercerizing operation is completed, the rollers, with the material thereon, may be removed from the trough and plunged into the washing-water, or the tension on the material may be removed and washing-water supplied from a second tank d<1>.
Patent GB-189714003-A (GB)
Title: Improvements in Cash Registers and Check Printers and Tills.
Filed: 1897-06-08
Granted: 1897-10-30
Abstract: 14,003. National Cash Register Co., [National Cash Register Co.]. June 8. Paging and numbering apparatus; type-writers and like machines.-Consists of detail improvements on the check till described in Specification No. 13,832, A.D. 1896, which improvements are applicable to other like machines. All the printing-discs E' have duplex type diametrically opposite so as to print a record strip A* and check ticket A<4> simul taneously The printing-discs consist of amount wheels set by striking the keys of the apparatus, numbering-wheels the unit of which is advanced. at each operation of the apparatus by a camactuated pawl G<2>, a fixed disc printing 'No.,' hand-set date wheels, and a hand-set wheel with distinguishing characters A, B, C, &c., to show, for example, the salesman who operated the machine, This disc is held by a pawl till the printing has been effected, and is then released by a cam and is returned to normal position by a spring. The p'atens S<2>, S<2> are carried by arms U<2>, U<2>, drawn towards the type by springs X<2>, X<2> but normally held back by a cam A<3> acting on the arm Z' of the lever Y<2>, Z<2>, W<5>. Twice in each rotation of the shaft W the cam allows the arms to be suddenly thrown forward by their springs and suddenly arrested by stops D<3>, D<3>. The platens S<2> are, however, connected to the blocks B<3> by guidepins and springs so as to continue the movement slightly and strike sharply on the type when printing. The first blow, however, is delivered upon the backs of inking-pads K<3>, L<3> which are carried by levers and thrown forward to the printing-line by a cam on the shaft W. These pads receive ink from the reservoir E<3>, and are caused to ink the type by the first stroke of the platens, the second effecting the printing after the pads have been drawn back. The ticket strip A<4> is fed intermittently by the rollers D<4>, E<4>, the latter preferably carrying type (such as the card of the firm) inked by the roller L<4>, which in turn receives ink at intervals from a reservoir M<4>, raised by the action of a cam Q<4> on a finger R'. A cam on the shaft R<1> engages at each rotation a notch in, and depresses, a bar S' carrying a knife blade G<4> for severing the ticket. A pawl Y<3> on the bar S<4> advances the record strip A*.
Patent GB-189715503-A (GB)
Title: Improvements in Electric Arc Lamps.
Inventor: IMRAY OLIVER
Filed: 1897-06-29
Granted: 1897-08-14
Abstract: 15,503. Imray, O., [General Incandescent Arc Light Co.]. June 29. Globe holders for electric arc lamps. A lamp is provided with outer and inner globes and globe holders. The upper carbon passes through a lid having a flange resting on the inner globe, the dimensions being such as to permit some lateral play of the cover with the carbon. The inner globe B may be held, as shown in Fig. 4, by a ring 22 bearing on a shoulder in it, and screwing on a screw surrounding the lower carbon - holder 14. This is attached to the frame 15 of the lamp by insulated screws. The outer globe 2 is secured in a cup 4, which in the arrangement shown in Fig. 4 is supported by a nut 11 and bolt 6 on a part 9 of the frame. The bolt has a crosshead 7, which may be turned and lowered through slots in the part 9 when the outer globe is to be lowered. When in place the nut 11 serves to raise the outer globe into contact with a cover on the lamp frame. A pin 7<a> and collar 12 limit the motions of the bolt and nut. In another arrangement, Fig. 5, the frame 15 carries a tube 32 in which the lower carbon is clamped, and which is screwed externally to receive a nut 33 supporting a cup 4 and the outer globe 2.
Patent GB-189717211-A (GB)
Title: Improvements in Paper Holding Devices.
Inventor: TRUSSELL EMORY AUDELL
Filed: 1897-07-21
Granted: 1897-09-11
Abstract: 17,211. Trussell, E. A. July 21. Filing papers.- Relates to a paper holder in which the sheets already inserted are firmly held while additional sheets are being put in, and which may be used for holding sheets for binding. The Figures show side views of the holder in two positions. The operating- lever 14 being thrown back, as shown in Fig. 4, papers A are inserted with their ends against the stops 3. The lever 14 is then brought forward, as shown in Fig. 5, when the main bar 6 held by the spring 8 secures the papers A on the board 1, while the secondary clip 11 is elevated by means of a spring. When papers are to be added, the lever 14 is thrown backwards, and the cam 16 raises the main bar 6 and depresses the secondary clip 11 to hold the papers already on the board. A slightlymodified form is described.
Patent GB-189721432-A (GB)
Title: Improvements in Brakes for Cycles.
Inventor: SLOWE CHARLES OWEN
Filed: 1897-09-18
Granted: 1898-04-02
Abstract: 21,432. Slowe, C. O. Sept. 18. Brakes actuated by rotating one of the handles. The handle e, mounted so as to turn on the handle-bar a, actuates through a flexible shaft d' a roller c carried in bearings d as shown in Fig. 2. A detachable plate a', secured over a hole in the handle-bars a, permits access to the roller c. A chain k, secured to the roller c by a screw k<1>, connects it to a rod f pivoted to a lever l, which carries the brake shoe. The lever l is pivoted to a plate g, Figs. 1 and 2, or to a clip l<1>, Fig. 5, secured to the steering-post h. A spring i depresses the rod f and releases the brake when the pressure is removed. When not in use, the handle e may be prevented from rotating by a spring pawl p secured to it, engaging a ratchet-wheel o fixed on the handle-bar a. The roller c may have teeth formed on it to engage the chain. The chain k may be replaced by a band.
Patent GB-189802895-A (GB)
Title: Improvements in or connected with Knitting Machines.
Inventor: WEDERMANN ALBERT
Filed: 1898-02-04
Granted: 1898-04-02
Abstract: 2895. Wedermann, A., and Grosser, G. F. Feb. 4. Parallel knitting- machines.-In order that the thread carrier may be fixed relatively to t h e cams, and still be in a position to supply yarn to the needles at the proper time when the carriage is travelling e i t h e r way, the central or draw-down cam a, a<1> is made to swing. The u pthrow cams d', d<2>, d<3>, d<4> are pivoted, and can be arranged to raise the needles to the full height, or to only half the full height, as in making cardigan work. In Figs. 7 and 7<a>, the cams are arranged for circular work or for work plain at one side. In Fig. 8, for cardigan work, the part a<8> of the central cam is bevelled so as to yield against a spring when the carriage is moving to the left, but deflects the needles to the bottom when the carriage moves to the right. The needle bits pass down guides a', a<3> formed by guard cams a<6>. In a modification, Figs. 13 and 14, two down-throw cams are used. They are bevelled at one side so that the needles press them into the cam plate when moving one way. The lower part a of the swing cam can be adjusted to regulate the length of loop.
Patent GB-189804388-A (GB)
Title: Improvements in Machinery for Shearing or Cutting Metallic Plates or Sheets and for other like Purposes.
Inventor: THOMAS HUBERT SPENCE
Filed: 1898-02-22
Granted: 1899-01-14
Abstract: 4388. Thomas, H. S. Feb. 22. Shearing.-A shearing-machine for cutting rolled black plates or other metallic or other sheets into pieces has fixed and moving blocks a, b with blades a<1>, a<2>, b<1>, b<2>. The pieces may be of polygonal or other shape, with straight or curved sides, provided one pair of edges is parallel. For cutting rectangular pieces, the blades are arranged to form three sides of a rectangle, the lower blades having their cutting-edges on the inner edge to co-act with the upper blades. The front blades a<1>, b<1> are fixed to the blocks, the side blades being adjustable to suit various widths. The front blades are divided, as shown in Fig. 5, so that the length of each may be varied by inserting wedges b<3> of various sizes, or the adjacent ends may be bevelled and overlap. In cutting the sheet, it is first held to trim one edge, and is then advanced till this edge butts against adjustable stops at the back of the machine, so that subsequent operations produce finished pieces. For cutting other shapes, the blades are arranged in a corresponding figure with one open side adjacent to the stops.
Patent GB-189807739-A (GB)
Title: Improvements in Pipe Cleaners
Inventor: SQUIRES ARTHUR CLIFTON
Filed: 1898-03-31
Granted: 1898-06-18
Abstract: 7739. Squires, A. C. March 31. Tobacco-pipe cleaners. - Consists of a rubber bulb for forcing air or liquid through the pipe. The bulb 1 has a dome-shaped top 2 with a thumb-button 3, a bead 4, and a funnel-shaped lower portion 5 with a tapering nozzle 6 for inserting into the pipe bowl.
Patent GB-189808632-A (GB)
Title: Improvements in the Driving Gear of Velocipedes.
Inventor: PATTON ISAAC PHILLIP
Filed: 1898-04-13
Granted: 1898-10-29
Abstract: 8632. Patton, I. P., and Seybold, J. A. April 13. Ball bearings for cycles. A ring H is mounted in ball bearings on a disc G, the bearings comprising balls b<1> carried between a U-shaped groove g formed in the disc G and two collars H<1> screwed into the ring H and having internal bevelled edges to engage the balls as shown. A piece H", carried in a groove in the ring H, is pressed inwards by a screw H<111> to lock the rings H' in position. The crank axle B is mounted in similar bearings in brackets a", in this case discs D being secured outside the bearing-rings to exclude dust &c.
Patent GB-189815499-A (GB)
Title: Improvements in Pantograph Engraving Machines.
Inventor: HOPE JOHN
Filed: 1898-07-14
Granted: 1898-11-12
Abstract: 15,499. Hope, J., and Hope, J. July 14. Engraving.-Pantograph machine for engraving rollers Fig. 1 shows a side elevation looking from the left-hand side of the machine. On the standard A are ways a supporting a table a<1> on which the enlarged pattern is secured. Secured to the standard A are ways a<2> on which runs a lower carriage a<4> having transverse ways a<5> on which the stylus carriage a<6> runs. The stylus a<7>, which is secured in a bracket hinged to the carriage a<6>, is moved over the pattern by the operator. The movement of the carriage a<6> along the ways a<5> is transmitted to the gravers by an arm C pivoted horizontally to a vertical shaft c, and the movement of the carriage a<4> is transmitted as a rotary movement to the cylinder E to be engraved by an arm D pivoted to a vertical shaft similar to the shaft c. On the shaft c is an arm c<1> having a groove in which a post c' is adjustably secured. The post c' engages a groove in an arm c<3> projecting from a carriage c<4>. The carriages c<4>, c<5>, c<6>, c<7>, which support the arms c<18> carrying the gravers, are arranged to reciprocate upon transverse ways adjustably secured at their ends to frames B' mounted on an arched frame or standard B secured to the ends of the standard A. The carriages c<4>, c<5>, and c' are secured to each other so as to move together by an adjustable connecting-bar, and the carriage c' may be similarly connected to the carriage c<5>, so that all four carriages move in the same direction. Or the carriage c' may be moved in the opposite direction by a lever c<11> pivoted at its centre at c<12> and having posts c<13>, c<15> on its ends for engaging grooves in adjustable parts of the carriages c<4>, c'. The roller E is supported at each end on a disc d<1>, and bears at the rear against a roller d' at each end. The rollers d<4> are adjustable for setting the roller E slightly diagonally for tracing the pattern spirally upon it, the carriage tracks being correspondingly set. One of the discs d' is milled on its periphery, and is rotated, to rotate the roller E, from the arm D. Secured to the milled disc is a disc having the ends of bands d<9> secured to its periphery, the other ends of the bands being secured at d<10> to the opposite ends of a carriage d<5> from which projects an arm engaging a post adjustably mounted on an arm of the vertical pivot shaft of the arm D. The gravers are lifted by rods e<3>, e<4>, e<5> connected to a weighted lever e<1> under the control of a treadle e. The arm e<3> may be connected with the upper carriage c<0> by extending the shaft c as indicated in dotted lines.
Patent GB-189815650-A (GB)
Title: Improvements in and relating to Recording Instruments for Musical Improvisations.
Inventor: NOWAKOWSKI TOMASZ
Filed: 1898-07-16
Granted: 1898-08-27
Abstract: 15,650. Nowakowski, T., and Stuckgold, S. July 16. Music recorders.-The actuation of any key a of a pianoforte causes the lever A to rock so as to bring the printing-roller e from the inking-wheel i against an abutment f and cause it to trace a line on a strip of paper driven by clockwork. The lines are thus proportional in length to the time value of the notes. The clockwork drives the roller i so as continually to supply fresh ink. The connection between the key and the lever A may be either electrical, as shown in full lines, or mechanical, as indicated in dotted lines. To transcribe the results into notes, the printed sheet is drawn slowly from a slit q over the roller V and between feed-rollers z, z<1> by turning the handle p. The casing at s is marked with a table of keys, by the help of which the copyist can readily transcribe the notes in the ordinary notation, their time value being indicated by the length of the dashes.
Patent GB-189817960-A (GB)
Title: Improvements in or relating to Swimming and Life-saving Appliances.
Inventor: MOGENSEN JORGEN ANTON PEDER
Filed: 1898-08-20
Granted: 1898-10-29
Abstract: 17,960. M o - gensen, J. A. P. Aug. 20. Body attachments. -A vest consisting of front and back halves a, b, connected by side and shoulder straps, bears long wedge-shaped air bags with the thick part upwards.
Patent GB-189822119-A (GB)
Title: Improvements in Apparatus for Facilitating the Delivery of Milk to Houses.
Inventor: MELTON FREDERICK
Filed: 1898-10-21
Granted: 1899-07-15
Abstract: 22,119. Melton, F. Oct. 21. Milk, delivering to houses.-Relates to apparatus, with - indicator attached, for facilitating the delivery of milk to houses. The apparatus comprires a plate b with hole for the insertion of a neck o on the cover of the can m, and of a funnel p carried by the milkman. The plate b is covered by a hinged flap c with a catch e for engagement with any suitable lock d. The plate b is also formed with a hole behind which works a disc g<1> operated by the handle k. The disc g<1> has printed upon it instruc. tions for the milkman, and a similar disc g is arranged on the handle k on the inside of the door. The can m is supported either on a hinged shelf l or from a bent hook n. A receptacle s, for a coin t to pay for the milk, may be attached to the plate b.
Patent GB-189902598-A (GB)
Title: Improvements in Back Rests for Chairs and other Seats.
Inventor: WEST JENNIE FREW
Filed: 1899-02-06
Granted: 1900-02-06
Abstract: 2598. Frew-West, J. Feb. 6. Chairs; seats; cushions.-Relates to back-rests which can be hung on to the top rails of the backs of chairs or seats. A frame consisting of side bars A, Fig. 2, connected by cross-pieces B, B', is hung on to the chair back. Riveted to the bars A. are springs C connected by a bowed cross-piece D. Wire work or webbing is secured to the springs C, directly, or by means of spiral springs. Figs. 3, 4, and 5 show a modification, in which two pairs of springs C' connected by bars B<2>, B<3> are suspended from the chair &c. back by hooks A'. The crossbar G, corresponding to the bar D, is connected by right and left handed screws I, J and a wing nut K to a cross-piece. By means of the nut the tension of the spring surface can be varied. Fig. 8 shows a simpler modification, and Fig. 7 one in which the suspending-hook can be adjusted in length. The double springs C<1>, Figs. 5 and 7, can rock on the supports.
Patent GB-189904729-A (GB)
Title: Rocking Blotter applicable for Advertizing.
Inventor: RAVENE WILHELM
Filed: 1899-03-03
Granted: 1899-04-08
Abstract: 4729. RavenÚ, W. March 3. Blotting-appliances.-A rocking blotter C is provided with a cardboard backing A and with a handle B of similar material, which is attached by turning down the ends B<1>. The parts can be detached and folded flat for transit. The blotting- device may bear advertisements.
Patent GB-189910227-A (GB)
Title: Improvements in or relating to Window Fasteners for Windows and analogous purposes.
Inventor: EDWARDS JOHN HENRY
Filed: 1899-05-15
Granted: 1899-07-15
Abstract: 10,227. Edwards, J. H. May 15. Sash fastenings.-Relates to improvements in the sash fastener described in Specification No. 21,911, A.D. 1898. The pivoted catch or tumbler a, which is made to fall by the closing of the sashes and is locked by a weight i, is made to engage the part f in such a way as to prevent horizontal separation of the sash bats. The engagement may be made by a projection f<1> on one part and a notch on the other as in Fig. 2, or by a shoulder l as in Fig. 4, or by other similar means.
Patent GB-189911187-A (GB)
Title: An Improved Signalling Apparatus.
Inventor: GROMPE CARL
Filed: 1899-05-29
Granted: 1899-07-08
Abstract: 11.187. Grompe, C. May 29. Signals, whistle.- Relates to signalling-apparatus for use on ships, in factories working without steam, or in remote situations, on railways for the purpose of stopping trains endangered by fog or snow &c., for signalling danger to life or property from fire &c., or for other signalling purposes. The apparatus consists of a steel bottle a, containing compressed carbonic acid and mounted on a portable stand d, and a whistle b connected to the bottle by an iron pipe c. When the valve v is opened, the whistle is sounded by the escaping gas.