baber/WOPTO huggingface dataset:
Patent CA-2199212-A1 (CA)
Title: Production of value-added milk by incorporation of specific dna sequences into mammary epithelial cells
Inventor: GAVORA JAN S
IPC: C12N15/85
Filed: 1997-03-05
Abstract: A method is described to transfer a gene encoding a valuable compound, such as a pharmaceutical, into the secretory cells of the mammary gland to produce a new compound into the milk or to alter the composition of the milk. In this method the packaging cell line producing the viral-derived particles is infused into the mammary gland. The packaging cells will attach and survive for a period of time within the mammary gland. While the cells are viable, they will supply a continuous source of viral-derived particles to trans-infect the maximum number of mammary epithelial cells.      After a period of time in the mammary gland, both the particles and the packaging cells will be destroyed by natural mechanisms while the trans-infected mammary epithelial cells continue to express gene(s) encoding the valuable compound or gene(s) to alter the composition of the milk. One or more genes can be trans-infected including DNA sequences that contribute to the efficient production of an active compound or to its stability. The packaging cells and the viral-derived particles used in this method can be those which trans-infect dividing or non-dividing cells and can be used either singly or together. This method can be used alone or in combination with other novel methods designed to ensure that the viral-derived particles are correctly positioned to trans-infect the mammary epithelial cells. Increasing the trans-infection of the mammary epithelial cells with the viral particles will result in a higher concentration of the valuable compound in the milk.
Patent CA-2200486-A1 (CA)
Inventor: DEVIC MICHEL
IPC: D21C9/16
Filed: 1997-03-19
Abstract: L'invention concerne un procédé de délignification et de blanchiment de pâtes à papier chimiques comprenant une ou plusieurs étape(s) de traitement par le peroxyde d'hydrogène, à une température supérieure à 100~C et sous pression élevée en présence d'un polymère et d'un composé A choisi parmi l'hydroxyde de potassium, l'hydroxyde de sodium et les carbonates d'un métal alcalin ou alcalino-terreux. Ce procédé permet d'obtenir une pâte fortement blanchie ayant conservé un bon degré de polymérisation.
Patent CA-2203671-A1 (CA)
Title: Controlling elements of a telecommunications network
Inventor: SPECTOR ADAM
IPC: H04M3/36
Filed: 1995-11-07
Abstract: A plurality of elements (A1, A2, B1, B2, B3, C1) of a system, such as a telecommunications network N are controlled by generating a generic instruction, in generator (14), selecting the elements for which the instruction is directed, in matcher (16) and interface module (19) and transmitting the instruction to the respective elements. By transmitting a generic instruction applicable to all relevant elements the operator (12) of the system can control all the elements with a single instruction. A generic instruction can be translated in translators (15a, 15b, 15c) into separate instructions applicable to each individual element or defined groups of elements.
Patent CA-2204707-A1 (CA)
Title: Quaternized blue anthraquinone hair dyes in an isatin/amine dye system
Inventor: BROWN KEITH C
IPC: A61K8/35
Filed: 1997-05-07
Abstract: Quaternized blue anthraquinone compounds of Formula I      wherein R1 and R2 are methyl and R3 is propyl, or R1 and R2 are ethyl and R3 is methyl and A- is a cosmetically acceptable anion, when employed in an isatin/amine dye system for the dyeing of hair enable the hair colorist to develop a full range of shades for the isatin/amine dye system. The compound of Formula I wherein R1 and R2 are methyl and R3 is propyl is preferred.      Compositions and a method of use employing same are disclosed.
Patent CA-2205406-A1 (CA)
Title: Novel benzyl pyrimidines
Inventor: JOLIDON SYNESE
IPC: C07C255/37
Filed: 1995-11-13
Abstract: Substituted 5-benzyl-2,4-diaminopyrimidines of general formula (I) in which R1 represents lower alkoxy, R2 represents bromine or lower alkoxy and R3 represents aryl, heteroaryl or a group -Q-R30, wherein Q  signifies ethylene, vinylene or ethynylene and R30 signifies aryl, heteroaryl, lower alkoxy-carbonyl or carbamoyl, as well as readily hydrolyzable esters of carboxylic acids of formula I and pharmaceutically acceptable salts of these compounds can be used in the control or prevention of infectious diseases.
Patent CA-2207006-A1 (CA)
Title: A food packaging unit, a method for manufacturing said food packaging unit and an apparatus for performing said method
Inventor: MARDER UWE MICHAEL
IPC: B26D3/18
Filed: 1997-06-04
Abstract: According to an illustrative example of the invention, a cheese package comprises a carrier tray (10) with a carrier surface (12) and side walls (14). Cubic cheese bodies (22) are loaded on the carrier surface (12) and laterally secured by the side walls (14). The cubic cheese bodies (22) have a height larger than the height of the side walls (14). A bag shaped of film material encapsulates the tray (10) and the cheese bodies (22) and secures the cheese bodies (22) on the carrier surface (12) of the tray (10).
Patent CA-2209039-A1 (CA)
Inventor: MORRISSEY PAUL DOUGLAS
IPC: B63B1/04
Filed: 1997-07-21
Abstract: In a device for floatation in water.  In this invention the lifecraft (capsule) which is so designed as to save lives at sea is fully rounded and has neither bow nor stern.  The roundness allows for greater strength since there are no weak stress points being either at the bow or stern location.  This device has double protection since there is an outer fully rounded wall as well as an inner fully rounded wall.  Both these independent movable spheres can be stopped at a determined position at the entry or exit by way of a locking device.  The lifecraft (capsule) will be gyroscopically fitted so as to allow minimum movement of the inner sphere where passengers are located, while at the same time the outer spherical unit will be allowed free movement, thus conforming to the wind and wave conditions which are often prevalent in the open sea.  The gyroscopic effect of this lifecraft (capsule) is brought about by way of an axis beam attached to the equator band at the centre of the gyrosphere lifecraft (capsule).  Bearings attached to the outside of the equator band allows free movement of both the inner and outer spheres, while keeping the inner spherical unit relatively calm in various sea stages.  A damper effect is also added with the bearing encasement in order to add more friction and thus allow less movement of the inner sphere.  Ballast is added at the centre of the lower portion of the inner sphere in order to allow the full lifecraft (capsule) at least sixty percent water immersion.  This partial underwater submersion lessens the roll and pitch of the lifecraft significantly.  The main purpose of the invention of the S.O.S. Gyrosphere Lifesaving Craft is to save lives at sea and to offer comfort to its passengers, including a reduction of motion sickness, as well as to offer bathroom facilities and other amenities not presently available in today's standard lifeboats.
Patent CA-2209051-A1 (CA)
Title: Optical reproducing method and apparatus for the same
Inventor: MEOUCH IVAN
IPC: G11B20/14
Filed: 1997-07-24
Abstract: A reading beam spot edge optical reproducing method and apparatus for the same for reading recorded information stored in the form of optical marks smaller in size than the size of the spot of a readout beam and reproducing such information data signals created by each individual recorded single optical data mark by scanning the sets of such readable marks of the optical recorded medium with reading impulse intervals adjusted to read one by one each single optical data mark by the reading beam spot edge and retrieving at the current reading impulse the output "0" or "1" data signal by analyzing current marks set data signal and its previous one marks set data signal that has been predetermined or memorized after its reading. The condition of the any one current marks set data signal could be changed or different from its previous one marks set data signal and/or its next one marks set data signal only by one single mark digital data signal "0" or "1", or the condition of the any one current marks set data signal could be unchanged or could be similar to its previous one marks set data signal and/or its next one marks set data signal, that is used in analyzing and reproducing process to output the current data signal equal by digital information meaning, "0" or "1", to the data signal created by a single mark located on the edge at the front end in the spot of the reading beam at the current signal reading impulse, that will be memorized within the current marks set data signal after its reading to be used in a future analyzing and reproducing process, according to the present invention.
Patent CA-2209677-A1 (CA)
Inventor: TANIGUCHI TOSHIHIKO
IPC: G03F7/40
Filed: 1996-11-08
Abstract: A treating fluid for making a waterless lithographic plate produced by applying a photosensitive layer and a silicone rubber layer in order to a support, characterized by containing at least one amine compound having at least two amino groups and at least one hydroxyl group in its molecule. It has excellent applicability and developability.
Patent CA-2213780-A1 (CA)
Title: Pharmaceuticals containing multipotential precursor cells from tissues containing sensory receptors
Inventor: GLOSTER ANDREW
IPC: C12Q1/02
Filed: 1997-08-22
Abstract: Current sources of neural stem and progenitor cells for neural transplantation are essentially inaccessible in living animals. This invention relates to neural precursor cells (stem cells, progenitor cells or a combination of both types of cells) isolated from the olfactory epithelium of mammals that can be passaged and expanded, and that will differentiate into cell types of the central nervous system (CNS), including astrocytes, oligodendrocytes, and tyrosine-hydroxylase-positive neurons. These precursor cells provide an accessible source for autologous transplantation in CNS, PNS, spinal cord and other damaged tissues.
Patent CA-2213877-A1 (CA)
Inventor: PEDAIN JOSEF
IPC: C08G18/40
Filed: 1997-08-19
Abstract: The present invention relates to a solvent-free, low viscosity binder composition which contains, in amounts sufficient to provide an NCO:OH equivalent ratio of 0.5:1 to 2.0:1, A) a polyisocyanate component containing one or more organic polyiso-cyanates and B) a solvent-free polyhydroxy component having a hydroxyl group content of3.0 to 18 wt.% and a viscosity at 23°C of 200 to 10,000 mPa.s, which contains B1) a hydroxy-functional polyacrylate component which is prepared by polymerizing a mixture of olefinically unsaturated monomers in which at least one monomer is hydroxy-functional in the presence of B2) a compound containing ether groups and having one or more hydroxy groups.   The invention also relates to the use of this binder composition in solvent-freetwo-component polyurethane coating compositions for coating metallic or mineral substrates.
Patent CA-2216191-A1 (CA)
Title: The rite form ab bench
Inventor: URBANI GABRIEL
IPC: A63B23/02
Filed: 1997-11-13
Abstract: Disclosed herein is an abdominal exercise bench. It includes a base that consists of an I shaped frame. An adjustable leg support and an adjustable foot support. A pad of a first length and a pad of a second length. The pad of the second length being 1/3 of the length of the first pad.
Patent CA-2216634-A1 (CA)
Title: Synergistic combinations of zidovudine, 1592u89 and 3tc or ftc
Inventor: BARRY DAVID WALTER
IPC: A61P31/12
Filed: 1996-03-28
Abstract: The present invention relates to therapeutic combinations of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol (1592U89), 3'-azido-3'-deoxythymidine (zidovudine) and (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (3TC) (or, alternatively to 3TC, (2R,cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (FTC)) which have anti-HIV activity. The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HIV infections including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors.
Patent CA-2218026-A1 (CA)
Title: Method for amplifying specific nucleic acid sequences
Inventor: TODD ALISON VELYIAN
IPC: C12Q1/6883
Filed: 1996-04-12
Abstract: The present invention provides a method of detecting a genetic polymorphism in an individual. In one form the method comprising the following steps: (1) obtaining a sample containing nucleic acid from the individual; (2) amplifying the nucleic acid sample from step (1) by a process involving thermocycling and primers, the amplification occurring in the presence of a thermostable restriction endonuclease which retains activity during thermocycling, the primers being selected such that they introduce into either the nucleic acid amplified from nucleic acid not including the polymorphism or from nucleic acid including the polymorphism, a sequence recognised by the thermostable restriction endonuclease; and (3) analyzing the product of step (2) to determine the presence or absence of the polymorphism.
Patent CA-2220098-A1 (CA)
Title: Cd6 ligand
Inventor: HAYNES BARTON F
IPC: C12N15/12
Filed: 1996-04-29
Abstract: The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction.
Patent CA-2220548-A1 (CA)
Title: Detection of loop-back conditions on faulty digital trunks
Inventor: NOLAN BRUCE
IPC: H04M3/24
Filed: 1996-05-08
Abstract: A method of detecting loopbacks on trunks in digital networks, comprises the steps of detecting an out-of-service trunk, continually placing a predetermined bit pattern on an outgoing channel of a trunk card, continually monitoring a receive channel of the trunk card to detect said bit pattern, and identifying the presence of a loopback when said bit pattern is persistently detected on the receive channel. This method avoids the need to dedicate a trunk channel for signaling purposes. By detecting the presence of loopbacks, intelligent networks can be prevented from unjustifiably clearing an alarm condition and returning traffic to a fault path.
Patent CA-2220741-A1 (CA)
Title: Optical isolator
Inventor: CHENG YIHAO
IPC: G02F1/09
Filed: 1997-11-12
Abstract: Tuning to maximize the isolation provided by an optical isolator to one of a predetermined plurality of wavelengths is achieved by tilting the isolator with respect to an input beam of light. Further tuning to a peak response for a given wavelength is achieved by rotation of the isolator about its longitudinal axis while or after tilting. In the manufacture of the isolator a test beam is launched into an output port end directed toward the input end. Tilting, or tiling and rotating is initiated and light at the input end is measured while tilting/rotating. When the position is determined where the minimal amount of light is measured, the optical elements are glued or secured in place, thereby providing a way to alter the response of an isolator for a given wavelength of input light.
Patent CA-2221044-A1 (CA)
Inventor: RAMSEY BETH C
IPC: B32B17/06
Filed: 1997-12-03
Abstract: The present invention provides a windshield with a heating arrangement to heat the wiper rest area of the windshield. The windshield includes first and second glass sheets secured together by an interlayer. A single, continuous resistance heating wire is secured between the glass sheets and makes multiple passes through a predetermined portion of the windshield generally corresponding to the wiper rest area such that the wire generates a desired power density within the predetermined portion to heat the wiper rest area. Opposing first and second ends of the wire extend to common connection area along an edge of the windshield and a connector secured to the wire ends provides for external electrical access to the wire. The wire may also extend along a marginal edge portion of the windshield generally corresponding to its A-post area. In one particular embodiment of the invention, an opaque ceramic band is bonded to a major surface of the second glass sheet, which forms the inner ply of the windshield, along its marginal edge portion such that the wire is not visible when the windshield is viewed through the second glass sheet. In addition, the wire may include a coating having a color that generally corresponds to the color of the opaque ceramic band to mask the appearance of the wire when the windshield is viewed through the first glass sheet.
Patent CA-2223704-A1 (CA)
Title: Water treatment with hydrogen peroxide and a polyquaternary ammonium stabilizer
Inventor: LINES MARY L
IPC: A01N59/00
Filed: 1996-05-30
Abstract: A method of treating water by adding hydrogen peroxide and a polyquaternary ammonium compound to the water. The hydrogen peroxide and the polyquaternary ammonium compound are independently added to the water so that the appropriate concentration of each component may be maintained in the water.
Patent CA-2225816-A1 (CA)
Title: Connecteur electrique ameliore
Inventor: TIMSIT ROLAND SION
IPC: H01R4/50
Filed: 1996-06-28
Abstract: L'invention concerne un connecteur électrique pour connecter des fils métalliques conducteurs (26, 27). Le connecteur comporte un élément en forme de C (10) ayant une partie centrale (12) et des parois courbes latérales (14). Les parois latérales (14) forment des canaux (20) pour recevoir les conducteurs. Le connecteur comporte en outre un coin (30) réalisé par moulage sous pression, venant se loger dans l'élément en forme de C (10). Le coin (30) a des canaux (36) pour recevoir des conducteurs, un sur chaque côté. Ces canaux sont concaves et ils ont une surface avec une texture. Le coin (30) vient se loger dans l'élément en forme de C (10) pour tenir ensemble les fils métalliques conducteurs (26, 27). Le fil métallique conducteur (26, 27) vient se loger entre le canal (20) pour recevoir le conducteur de l'élément en forme de C (10) et le canal (36) pour recevoir le conducteur du coin (30).
Patent CA-2225870-A1 (CA)
Inventor: HENDRY JAMES WATSON
IPC: B29C45/00
Filed: 1997-12-24
Abstract: A mold apparatus and method is used to form a solid injection molded plastic part having no internal voids, a Class A finish, a sink-free exterior appearance surface, and unevenly distributed structural detail extending from the opposite surface, the detail including free-standing reinforcement ribs, attachment bosses, and the like, In sequence, a seal groove in the mold cavity is reduced to a pressure below atmospheric (i.e., negative), a charge of hot thermoplastic is introduced into the mold cavity and seal groove whereby to form a gas seal ring, and pressurized gas is injected into the mold cavity, The pressurized gas forces the hot plastic from one mold half against the other mold half, and the gas seal formed by the plastic prevents gas on one side of the thermoplastic from reaching the appearance surface of the part.
Patent CA-2227412-A1 (CA)
Inventor: FREDJ ABDENNACEUR
IPC: C11D3/37
Filed: 1996-07-12
Abstract: A detergent composition inhibiting dye transfer based on vinylpyridine copolymers, wherein the molar ratio of copolymerizing monomer to vinylpyridine is from 1 to 0.01, preferably from 0.5 to 0.05, most preferably from 0.3 to 0.05.
Patent CA-2231632-A1 (CA)
Title: Use of creatine analogues for the treatment of disorders of glucose metabolism
Inventor: TEICHER BEVERLY A
IPC: A61K31/198
Filed: 1996-10-11
Abstract: The present invention relates to the use of creatine compounds including cyclocreatine and creatine phosphate for treating or preventing a metabolic disorder consisting of hyperglycemia, insulin dependent diabetes mellitus, impaired glucose tolerance, hyperinsulinemia, insulin insensitivity, diabetes related diseases in a patient experiencing said disorder. The creatine compounds which can be used in the present method include: (1) analogues of creatine which can act as substrates or substrate analogues for the enzyme creatine kinase; (2) compounds which can act as activators or inhibitors of creatine kinase;  (3) compounds which can modulate the creatine transporter, (4) N-phosphocreatine analogues bearing transferable or non-transferable moieties which mimic the N-phosphoryl group; (5) compounds which modify the association of creatine kinase with other cellular components.
Patent CA-2234066-A1 (CA)
Title: Substituted imidazoles having anti-cancer and cytokine inhibitory activity
Inventor: SELNICK HAROLD G
IPC: A61K31/495
Filed: 1996-10-02
Abstract: Compounds represented by formula (I), are disclosed.      AR represents an aromatic group containing 6-10 atoms; and (a) represents a 4 to membered non-aromatic heterocycle containing at least one N atom, and optionally containing 1-2 additional N atoms and 0-1 O or S atom.      A pharmaceutical composition is also included. Methods of treating cancer and cytokine mediated diseases are also included.
Patent CA-2234998-A1 (CA)
Title: Xylanase, oligonucleotidic sequence encoding it and its uses
Inventor: PEREZ SERGE
IPC: C12N9/24
Filed: 1996-10-15
Abstract: Xylanase stable at 60 ~C and having a sequence comprising 182 aminoacids, and oligonucleotidic sequence encoding it. This oligonucleotidic sequence, comprised in an appropriate vector, allows the production of xylanase.
Patent CA-2235920-A1 (CA)
Inventor: HIRAKODAMA ISAO
IPC: H04W76/02
Filed: 1997-09-18
Abstract: Lorsqu'on met sous tension une station mobile, les informations d'identification de la station mobile sont lues dans la zone de mémoire non volatile du module d'informations de l'abonné, tandis que les informations d'identification du module sont lues dans la zone de mémoire non volatile de la station mobile. Les informations d'identification de la station mobile ainsi lues et les informations d'identification de la station elle-même sont collationnées, tandis que les informations du module d'identification ainsi lues et les informations d'identification de l'abonné du module d'informations de l'abonné introduit dans la fente sont collationnées. Lorsque les informations d'identification du module ne coïncident pas, les informations de traitement des communications sont lues dans le module d'informations de l'abonné introduit dans la fente, le contenu correspondant stocké dans la zone de mémoire non volatile de la station mobile est actualisé par stockage des informations d'identification du module d'informations de l'abonné dans la zone de mémoire non volatile de la station mobile, tandis que les informations correspondantes sont actualisées par stockage des informations d'identification de la station mobile dans la zone de mémoire non volatile du module d'informations de l'abonné. Ensuite, les informations de traitement des communications stockées dans la zone de mémoire non volatile de la station mobile sont lues pour faire passer le mode à l'état de communication. Lorsque les collationnements décrits ci-dessus s'avèrent coïncider, les informations de traitement des communications enregistrées et verrouillées précédemment dans la zone de mémoire non volatile de la station mobile sont lues pour passer à l'état communicable.
Patent CA-2236389-A1 (CA)
Title: Internet-enabled service management system and method
Inventor: LIM CHANG
IPC: H04L12/24
Filed: 1998-04-29
Abstract: A system and method for the management of communication services from a service provider by a customer of the provider. The management system employs an Internet-based architecture that provides access to user's virtual private networks via an end user browser. The customer service management (CSM) system service director (SD) maintains a relational database for storing user specific information retrieved from the network manager.