baber/WOPTO huggingface dataset:
Patent EC-SP003848-A (EC)
Title: Inhibidores de la proteinasa del c del procolageno
Inventor: BAILEY SIMON
IPC: C07D271/06
Filed: 2000-12-21
Abstract: Los compuestos de la fórmula (I): (gráfico), y sus sales, solvatos, profármacos, etc. En los que los sustituyentes tiene los valores mencionados en este documento, son inhibidores de la proteinasa C de procolágeno (PCP) y tiene utilidad en afecciones mediadas por PCP.
Patent EC-SP034595-A (EC)
Title: Agonista del receptor alfa activado del proliferador de peroxisomas
Inventor: JOHNSTON RICHARD DUANE
IPC: A61K31/42
Filed: 2003-05-08
Abstract: (c) R2 es Ho un grupo sustituido o insustituido seleccionado del grupo constituido por alquilo C1-C6, alilo C1-C6, arilalquilo Co-C4, heteroari-alquilo C0-C4, sulfonamida, amida, OR10 y cicloalquilo C3-C6; (d) X es un alquileno C1-C5 de unión opcionalmente sustituido en el que un átomo de carbono del elemento de unión puede estar sustituido con O, NH o S; (e) Y es C, O, S, NH o un enlace sencillo; y (f) E se selecciona del grupo constituido por hidrógeno, C (R3) (R4) A, A, sustituido o insustituido, seleccionado del grupo constituido por hidrógeno, C(R3) (R4) A, A, sustituido o insustituido , seleccionado del grupo constituido por (CH2)n COOR19, alquilo C1-C4, aminoarilo y aminoalquilo C1-C4 y en la que n es 0, 1, 2 o 3, A es un grupo funcional seleccionado del grupo constituido por carboxilo, alquilnitrilo C1-C3, carboxamida, sulfonamida sustituida o insustituida y tetrazol sustituido o insustituido; R3 es H, alquilo C1-C5 saturado o insaturado, alcoxi C1-C5, y R4 es H, halo, un grupo sustituido o insustituido seleccionado entre alquilo C1-C5, alcoxi C1-C5, cicloalquilo C3-C6, arilalquilo C0-C4 y fenilo o R3 y R4 se conbinan para formar un cicloalquilo C3-C4; R19 se selecciona del grupo constituido por hidrógeno, arilmetilo opcionalmente sustituido y alquilo C1-C4 opcionalmente sustituido; R8 se selecciona independientemente del grupo constituido por hidrógeno, alquilo C1-C4, alquilenilo C1-C4 y halo; R9 se selecciona independientemente del grupo constituido por hidrógeno, alquilo C1-C4, alquilenilo C1- C4, halo, arilo sustituido o insustituido, arilalquilo C1-C4 sustituido o insustituido, heteroarilo sustituido o insustituido, slilo V1-C6 y =R10; y R10 se selecciona independientemente del grupo constituido por hidrógeno y alquilo C1-C4.
Patent EC-SP034695-A (EC)
Inventor: DEGADY MARC
IPC: A23G1/00
Filed: 2003-07-18
Abstract: A three-phase center-filled candy product. A candy material for the outer layer or shell is extruded from a first extruder and a second material which could be a chewy material, such as gum or bubble gum, is extruded as an inner layer from a second extruder. A semi-liquid center-fill material is inserted into the inner layer. The three-phase rope of material is formed into individual pieces or tablets of candy in a forming machine. Sticks can be added to form lollipops in one embodiment. The formed products are then cooled, tumbled and prepared for further processing.
Patent EC-SP034932-A (EC)
Title: Derivados de tetrahidroquinolina
Inventor: VAN STRATEN NICOLE CORINE RENEE
IPC: C07D401/12
Filed: 2003-12-30
Abstract: La presente invención se refiere a derivados de tetrahidroquinolina que presentan la fórmula general (I) o a una sal farmacéuticamente aceptable del mismo, en donde R1 es formulo, (1-6C)alquilcarbonilo o (1-6C)alquilsulfonilo; R2 y R3 son H o (1-4C)alquilo; R4 es fenilo; R5 es (1-4C)alquilo; Y-X es (CO)-O, (SO)2-O, NHC(O)-O, NHC(S)-O, OC(O)-O, enlace-O, C(O)-NH, S(O)2-NH, NHC(O)-NH, NHC(S)-NH, OC(O)-NH, enlace-NH, NH-C(O), O-C(O), NH-S(O)2 u O-S(O)2 o Y-X es un enlace; R6 es H, trifluorometilo, (1-6C)alquilo, 1- ó 2-adamantil(1-4C)alquilo, (2-6C)alquenilo, (3-9C)heteroarilo, (3-6C)cicloalquilo, (2-6C)heterocicloalquilo, (1-4C)alquiltio(1-4C)alquilo, (6-10C)aril(1-4C)alquilo, (3-9C)heteroaril(1-4C)alquilo, (3-6C)cicloalquil(1-4C)alquilo,(2-6C)heterocicloalquil(1-4C)alquilo, R8, R9-aminocarbonil(1-4C)alquilo, R8, R9-amino(1-4C)alquilo, R8-oxicarbonil(1-4C)alquilo, R8-oxi(1-4C)alquilo, R8-carbonil(1-4C)alquilo o (6-10C)arilo; R7 es H, (1-4C)alquilo, (1-4C)alcoxi, halógeno, trifluorometilo, ciano, nitro, hidroxilo; y R8 y/o R9 es H, (1-4C)alquilo, (2-4C)alquenilo, (2-4C)alquinilo, (6-10C)arilo, (3-9C)heteroarilo, (6-10C)aril(1-4C)alquilo, (3-9C)heteroaril(1-4C)alquilo, (3-6C)cicloalquil(1-4C)alquilo, (2-6C)heterocicloalquil(1-4C)alquilo, (1-4C)(di)alquilamino(1-4C)alquilo, (1-4C)alcoxi(1-4C)alquilo, (1-4C)alquiltio(1-4C)alquilo, (1-4C)alquilcarbonilamino(1-4C)alquilo, (1-4C)alcoxicarbonil(1-4C)alquilo, (1-4C)alcoxicarbonilamino(1-4C)alquilo, (3-6C)cicloalquilo, (2-6C)heterocicloalquilo o R8 y R9 pueden estar unidos en un anillo (2-6C)heterocicloalquilo. La presente invención también se refiere a composiciones farmacéuticas que comprenden dichos derivados y al uso de estos derivados para el control de la fertilidad
Patent EC-SP045261-A (EC)
Title: Inhibidores de la cisteín-proteasa catepsina
Inventor: BAYLY CHRISTOPHER I
IPC: C07C259/10
Filed: 2004-09-01
Abstract: Esta invención se refiere a una nueva clase de compuestos que son inhibidores de cisteín-proteasa, incluyendo pero sin limitación, inhibidores de catepsinas K, L, S y B. Estos compuestos son útiles para tratar enfermedades en las que está indicada la inhibición de la resorción ósea, tales como la osteoporosis.
Patent EC-SP930954-A (EC)
Title: Mejoras al sistema de encamisado como refuerzo a tuberias
Inventor: SILVA LOPEZ JESUS
IPC: F16L58/10
Filed: 1993-07-26
Abstract: Se refiere a un sistema de encamisado como refuerzo para tuberías, y en especial a tuberías petrolíferas que se caracteriza porque incluye un encamisado, unos elementos de unión entre la camisa y el tubo conductor, una resina alojada en el espacio entre la tubería y la camisa, unos penetradores o coples para la inyección d ela resina y medios de soldadura entre el cuerpo principal del encamisado y el elemento de unión.
Patent FI-20002801-A (FI)
Inventor: BOURKE PETER
IPC: C02F1/24
Filed: 2000-12-20
Abstract: The invention relates to a flotation machine which at least contains a flotation cell having a means for feeding slurry in the flotation cell, a means for feeding air into the slurry and producing froth, a means for removing froth from the flotation cell and a means for removing tailings from the flotation cell. According to the invention the flotation cell ( 1,21 ) is provided with at least one rotating froth removal device ( 8,26 ) immersed at least partly in the froth ( 9,27 ) and so shaped that one end of the froth removal device ( 8,26 ) is extendible over the launder ( 12 ) attached to the flotation cell ( 1 ) in order to recover the froth ( 9,27 ) from the flotation cell ( 1,21 ) using the centrifugal force generated by the froth removal device ( 8,26 ).
Patent FI-20022005-A (FI)
Inventor: SMAHL JARMO
IPC: F16B7/18
Filed: 2002-11-08
Abstract: A first element is connected to a first end of the connecting piece and a second element is connected to a second end of the connecting piece. At least one end of the connecting piece is provided with a thread, whereby the connecting piece is connectable for instance to a pipe or fitting with threaded connection. The connecting piece may be made of plastic, for example, the connecting piece is made substantially completely of thermoplast in such a way that the thermoplastic body is provided with a thread. The outer surface of the connecting piece is provided with a gripping member. The gripping member is formed and dimensioned such that it gives way earlier than the connecting member thread and/or basic structure.
Patent GB-1050841-A (GB)
IPC: C07C409/22
Abstract: 1,050,841. Stabilized ketone peroxide solutions. WALLACE & TIERNAN Inc. April 2, 1964 [April 2, 1963], No. 13652/64. Heading C2C. Stable aqueous solutions of lower ketone peroxides including one or more polymers thereof are prepared by reacting at a pH below 4À5 a lower ketone, i.e. containing up to 8 carbon atoms, with aqueous hydrogen peroxide of at least 30% strength at below 30 C. in the presence of at least one inert organic hydrophilic solvent and then stopping the reaction by raising the pH of the liquid reaction product mixture to give a resultant pH of the mixture of 4À5 to 7. The desired reaction pH may be readily attained by use of a cationic ionexchange resin in its acid form or from aqueous hydrogen peroxide itself and the increase of pH to stop the reaction may be effected by addition of a base, preferably a basic inert organic hydrophilic solvent, and/or by separating the exchange resin, if present, from the reaction mixture. Preferred hydrophilic solvents are cyclic amides, alcohols, glycols, polyols, ethers and esters. The aqueous solutions obtained can be employed as catalysts in the polymerization of unsaturated polyesters. Reference has been directed by the Comptroller to Specification 827,511.
Patent GB-1050945-A (GB)
IPC: D03D43/00
Abstract: 1,050,945. Loom drop box motions; stop motions. RUTI MACHINERY WORKS Ltd. June 18, 1965 [June 18, 1964], No. 25995/65. Heading D1E. A give-way device between a drop box motion 26 and the box lifting rod 41 consists of a sector 29 having indentations 61, in the middle one of which rests a roller 60 carried by a lever 40. If the shuttle jams, an attempt by the rod 26 to move the box causes the roller 60 to ride into one of the other indentations, thereby recoupling the parts in a configuration that will bring a cell of the box exactly in line with the shuttle race; consequently, the worst defect that can occur is that the wrong shuttle will be picked if the loom is not stopped in time to prevent this happening; to stop the loom, a switch 74 is released when the roller 60 rides out of its normal indentation and remains open owing to the other indentation being shallower than the normal one. Instead of the switch 74, the arm 72 may be replaced by a bellcrank lever, the horizontal arm of which is linked to trip the loom starting handle to stop the loom. The sector 29 may be replaced by a straight bar moving parallel with the box lifting rod 41, which carries a spring-loaded plunger engaging notches in the bar.
Patent GB-1053614-A (GB)
IPC: D06P5/06
Abstract: 1,053,614. Dyeing and printing cellulose. SANDOZ PATENTS Ltd. Feb. 7, 1964 [Feb. 8, 1963], No. 5364/64. Heading D1B. Fibres of natural or regenerated cellulose are dyed or printed with dyes, or dye precursors, which contain at least one reactive amino or hydroxyl group and treated with a compound of the formula: wherein Hal is Cl or Br, X is H or -CH 3  and R 1  is an alkyl, cycloalkyl, aryl or aralkyl radical of at least 6 C atoms; when dye precursors are employed they are then converted into the finished dyestuffs. Of the numerous compounds of Formula (I) specified those employed in the examples are N-cyclohexyl and N - cyclooctyl- N,N-bis-(#-chloroethyl)-aminehydrochloride. Said compounds may be applied to the fibres before, after or simultaneously with the dyestuff and fixation may be carried out (a) in the dyebath or in a fresh bath in the presence of acid-binding agents at 20-100‹C., (b) with dry heat at 110-200‹C. under neutral to acid conditions or (c) by steaming at 100-150‹C. under neutral to acid conditions. The presence of a non-ionic dispersant in the fixing bath is sometimes advisable. Examples of dyeing and padding fabrics of cotton and viscose in which a number of direct dyes and some disazo-copper complex dyes are specified are given.
Patent GB-1054167-A (GB)
IPC: C07C45/34
Abstract: 1,054,167. Oxidation catalysts. ALLIED CHEMICAL CORPORATION. May 18, 1965 [May 18, 1964], No. 21066/65. Heading B1E. [Also in Division C2]. Oxidation catalysts e.g. bismuth vanado molybdate, tin boromolybdate, tin arsenomolybdate and tin vanadomolybdate are made by contacting (1) a major amount of a salt of Mo and (2) a minor amount of a salt of vanaduim or arsenic with (3) a solution of a salt of Bi or Sn. In modifications (1) may be a salt of W, and (2) may be a salt of B. The catalysts may be supported e.g. on Al 2 O 3  or SiO 2 .
Patent GB-1225896-A (GB)
IPC: C22C19/00
Filed: 1969-03-12
Abstract: 1,225,896. Alloys. METALLGESELLSCHAFT A, G, and KERN FORSCHUNG m. b. H, GES. FUR. March 12, 1969 [March 14, 1968], No.13086/69. Heading C7A. [Also in Divisions E1, F2, G6] Composite cladding material for a nuclear fuel element comprises an inner layer of a vanadiumbased alloy and a metallic outer layer resistant to corrosion by the coolant. The vanadium alloy may contain one or more of the elements Ti, Nb, Zr, Cr, Mo, Ta, W, Co, Ni, Be, Si, Fe, Y, and rare earths. Particularly suitable are alloys containing 1-20% Ti, 0-20% Nb, balance V. For use with liquid sodium coolant the metal outer layer may be of pure iron, iron alloy, nickel, nickel alloy, or molybdenum or molybdenum alloy, which may contain titanium or zirconium carbide. When the coolant is steam, the outer layer may be nickel, nickel alloy, or high grade steel. For CO 2  coolant, high grade steel or zirconium alloy are suitable. Contents of carbon, nitrogen, and oxygen in the metallic outer layer should each be below 0À01%; contents higher than this may be rendered innocuous by addition of Nb or Ti to form carbides and nitrides or of Al to form oxide. The composite material may be made by extrusion, shrinking tubes together, or roll or explosion cladding. Spacers for fuel rods may be made by placing a sheet of vanadium alloy between two sheets of nickel alloy, enclosing in an oxidation-preventing stainless steel shell, rolling, removing the shell, and forming to shape.
Patent GB-1226643-A (GB)
IPC: A61B5/087
Filed: 1968-03-21
Abstract: 1,226,643. Spirometers. DONTI RESEARCH DEVELOPMENT MFG. March 21, 1968 [March 27, 1967], No. 13627/68. Heading G1N. [Also in Division A5] Apparatus for analysing gas flow rates, particularly breathing rates, comprises a heated resistance transducer in a bridge circuit measuring the gas flow rate by the change in temperature and resistance, and additional circuitry for calculating peak and average flow and to operate an alarm when the gas flow is interrupted. The transducer, comprising a V-shaped platinum resistance wire 43 Fig. 5C, mounted inside a plastic tube assembly between screens 168, 169 Fig. 5B, forms one arm of a bridge circuit 3 Fig. 2 and is heated by the bridge current, the transducer voltage being maintained constant by a voltage regulator 1. When the temperature and resistance of wire 43 is changed by a gas flow past it, a bridge unbalance signal appears at lead 62 indicative of the rate of flow. The signal peak value is developed across capacitor 72 Fig. 3 for selected indication on a meter 71 by operation of switch 78. The signal voltage is also led through a linearizing network 8, potentiometer 85 and integrator 88, to be fed to capacitors 89, 90, 91, the individual charging circuits being opened after 1, 2 or 15 seconds respectively by pulses from generator 99, controlling relays 96, 97, 98. The charges on capacitors 89, 90, 91, representing volume flows during 1, 2 and 15 seconds intervals respectively, are fed via contacts of selector switch 78 to meter 71. The signal from the linearizing circuit 88 may alternatively be fed to capacitor 181 through resistors 179, 180, the time constant being such that the charge on capacitor 181 represents the volumetric flow during one minute.
Patent GB-1228195-A (GB)
IPC: C08K5/521
Filed: 1968-07-11
Abstract: 1,228,195. Alkylpyrophosphate salts. ARGUS CHEMICAL CORP. 11 July, 1968 [17 July, 1967], No. 33087/68. Heading C2C. [Also in Division C3] Alkyl polyphosphate salts are obtained by reacting phosphorus pentoxide with the appropriate aliphatic alcohol and metal oxide or hydroxide in the presence of water. The preparation of the following is described:
Patent GB-1231328-A (GB)
IPC: F25J3/04
Filed: 1969-07-17
Abstract: 1,231,328. Cold separation of air. MESSER GRIESHEIM G.m.b.H. 17 July, 1969 [31 July, 1968], No. 36130/69. Heading F4P. In an air rectification process for the simultaneous production of liquid and gaseous oxygen withdrawn from a column 1 through lines 5, 2 respectively, at least a portion of the gaseous oxygen which has a lower hydrocarbon content than the liquid product in line 5 is compressed at 3, liquefied in a heat exchanger 8, cooled by said withdrawn liquid oxygen and fed to a storage container 13 from which it is subsequently withdrawn, vaporized and used in breathing apparatus. As shown oyxgen gas from the warm end of exchanger 8 is returned through a line 12 to column 1 but in a modification the gas is fed under pressure to storage containers (17, Fig. 2, not shown).
Patent GB-1256728-A (GB)
IPC: A47L9/12
Filed: 1969-07-01
Abstract: 1,256,728. Suction cleaners. RECKITT & COLMAN PRODUCTS Ltd. June 26, 1970 [July 1, 1969], No.33231/69. Heading A4F. A suction cleaner which may be used for removing cleaning liquid from floors and including a suction unit adapted to rest on an open top receptacle 27 for collecting dust or liquid, comprises a motor 9 driving a fan in a housing 8 located in central apertures in dish-shaped members 1, 4 of plastics material, and with their edges in engagement to form a compartment 24 beneath a compartment 20 formed between the member 4 and a cover member 17. Cooling air for the motor 9 is drawn by a further fan therethrough through parts 22 provided by undulations in the member 17 or in a plate 21 covering a central aperture 16 in the latter. The cooling air is discharged from the compartment 20 through parts 18 provided by undulations in either of the members 4, 17. Air exhausted by the suction fan passes into the compartment 24, and leaves the latter through downwardly directed peripheral apertures 25. When the apparatus is used for dust collection the dust laden air is drawn into the receptacle 27 through an inlet pipe 42 having a T-piece outlet to which a dust bag is attached, and is drawn into the fan housing 8 via an annular glass fibre filter 40 and a polyethylene screen 41. When liquid is collected the dust bag is removed, and to prevent liquid being drawn into the fan housing 8 a valve member 36 is actuated by a float 35 to close the inlet to the housing 8 when the liquid in the receptacle 27 reaches a predetermined level.
Patent GB-1258008-A (GB)
IPC: H01L23/049
Filed: 1969-04-09
Abstract: 1,258,008. Making semi-conductor devices; jointing by stamping; spinning. WESTING- HOUSE ELECTRIC CORP. 9 April, 1969 [10 April, 1968], No. 18130/69. Headings B3A, B3J and B3Q. [Also in Division H1] The spring loaded contacts of a semiconductor device are assembled in the jig shown in Fig. 3. The active elements of the device, contacts and springs are stacked within the upstanding peripheral wall 24 of a threaded header and the header seated on recessed member 82. This is then pushed upwards until a flange on hollow plunger 86 engages ledge 92 on the striking plate 94 at which point the lower faces of peripherally spaced striking tools 98 and plunger 86 lie in the same plane. Movement is continued until the requisite loading is applied to the spring at 90 whereupon the staking tools are pneumatically driven through slots in the plunger to punch dimples in wall 24 to retain the spring with the desired loading. If the device is found to be unsatisfactory when tested it can be dismantled using the tool shown in Fig. 8 mounted in a jig as in Fig. 3. In this case as the device is pressed upwards plunger 302 moves downwards relative thereto thus rocking pivoted members 316 so that their lower ends move outwards to flatten the dimples. After re-assembly new dimples may be formed between the original. The staking tools of Fig. 3 can be replaced by a rotatable roll forming tool (Fig. 11, not shown) which is pressed against the wall as the device is rotated on its axis to form a peripheral protrusion on the inner surface of the wall.
Patent GB-1259192-A (GB)
IPC: F16L17/035
Filed: 1969-02-19
Abstract: 1,259,192. Joint-making packing; pipe joints. CELANESE BUILDING COMPONENTS Ltd. 19 Feb., 1969, No. 8922/69. Addition to 1,080,816. Headings F2B and F2G. The seal disclosed in the parent Specification is modified by the provision of a ring 9 at the end of the funnel-like portion 7, for carrying concentric sealing ridges 4 for engaging the wall of the pipe to be sealed. The seal may be manufactured to suit different sizes of pipes by providing a second ring 12 which may be cut off when not required.
Patent GB-1264361-A (GB)
IPC: B29D30/28
Filed: 1969-02-21
Abstract: 1,264,361. Tyre-bead turn-up and stitching device. VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I KONSTRUKTORSKY INSTITUT PO OBORUDOVANIJU DLYA SHINNOI PROMYSHLENNOSTI. 21 Feb., 1969, No. 896/69. Heading B7C. A device for turning-over and stitching plies around a bead core in a tyre-building drum 14 comprises a stitching roller 9 rotatable on an arm 8 pivoted at 7 to a link 6 and connected to the piston-rod of a piston and cylinder device 10 which moves roller 9 around the bead core 13 and applies stitching pressure thereto, the speed of movement being controlled by a dashpot 12, preferably an hydraulic dashpot. All the parts are pivoted to a plate 1 which can be fixed to the tyre-building machine. As the roller passes towards the inside of the bead region, it lifts the region away from the drum end, enabling the roller to apply stitching pressure on the axially inner surface of the region.
Patent GB-1264825-A (GB)
IPC: C08L53/00
Filed: 1969-06-19
Abstract: 1,264,825. Block polymer-polyethylene compositions. FARBWERKE HOECHST A.G. 19 June, 1969 [19 June, 1968], No. 31033/69. Heading C3P. A composition comprises (a) 70 to 99À5% of an ethylene-propylene block copolymer having 1 to 30% ethylene and a melt index i 10  at 190‹ C. of 0À5 to 60 and (b) 0À5 to 30% of a polyethylene having a melt index i 2  at 190‹ C. of 0À4 to 80. The compositions may be obtained by mixing above the softening points of the polymers i.e. 150‹ to 300‹ C.
Patent GB-1265658-A (GB)
IPC: G06F15/02
Filed: 1968-07-19
Abstract: 1,265,658. Digital calculator. BELL PUNCH CO. Ltd. 18 July, 1969 [19 July, 1968], No. 34702/68. Heading G4A. The disclosure is substantially the same as that of Specifications 1,265,657 and 1,261,710 by the same applicant. The claims are directed to the division process.
Patent GB-1265794-A (GB)
IPC: C07D209/56
Filed: 1968-05-21
Abstract: 1,265,794. Adamantano[2,1 -6]tetrahydropyrrol-2-ones. LILLY INDUSTRIES Ltd. 21 May, 1969 [21 May, 1968], No. 24089/68. Heading C2C. Novel adamantano [2,1-6] 6] tetrahydropyrrol- 2-ones of the general formula wherein R and R<SP>1</SP> are each a hydrogen atom or a C 1-4  alkyl group, are prepared (a) by cyclization of a 2-amino - 1 -adamantane-acetic acid of the general formula or (b) when R<SP>1</SP> is a hydrogen atom, by cyclization of an acid azide of the general formula in photolytic conditions. 1 -Aclarnantane-acetic acid hydrazide is prepared by reaction of 1-adamantane-acetic acid with methanol and treatment of the resulting 1-adamantane-acetic acid methyl ester with hydrazine. 2 - Amino - 1 - adamantane - acetic acid is prepared by reductive amination of 2-(2-ketoadamant-1-yl) acetic acid. Pharmaceutical compositions having a depressant effect on the central nervous system comprise, as active ingredient, an adamantano- [2,1-6]tetrahydropyrrol-2-one of the first general formula above, together with a pharmaceutical carrier.