baber/WOPTO huggingface dataset:
Patent PT-1300407-E (PT)
Inventor: BONO IGNACIO-JOSE MIQUEL
IPC: G03B27/16
Filed: 2001-06-25
Abstract: The invention relates to carbamates having general structure (I), wherein: R1, R2 and R3 are H, OH, SH, CN, F, Cl, Br, I, (C1-C4)-alkylthio, (C1-C4)-alkoxyl, (C1-C4)-alkoxyl substituted by one or several F radicals, carbamoylamine, (C1-C4)-alkyl and (C1-C4)-alkyl substituted by one or several F or OH radicals; R4 represents a substituted or non-substituted cycloalkyl or cycloaryl radical (a heteroalkyl radical or not). The amine of the quinuclidine ring can also be forming quaternary ammonium salts or in an oxidized state (N-oxide). Carbamates (I) are antagonists of the M3 muscarinic receptor, and selectively, the M2 receptor. Hence, they can be used in the treatment of urinary incontinence (particularly due to bladder instability), irritable bowel syndrome, diseases of the respiratory tract (particularly chronic obstructive pulmonary disease, chronic bronchitis, asthma, emphysema and rhinitis) and in ophthalmologic operations.
Patent PT-1438961-E (PT)
Title: Bioequivalent composition of itraconazole dispersed in a hydrophilic polymer
Inventor: SETH PAWAN
IPC: A61K31/496
Filed: 2003-01-14
Abstract: The invention provides an itraconazole composition comprising itraconazole dispersed in a hydrophilic polymer, and, optionally, a surfactant, having a dissolution at 30 minutes between 10 and 40%, at 45 minutes between 25 and 80%, at 60 minutes between 60 and 95%, at 90 minutes at least 80%, as measured using the type II paddle method at 100 rpm according to the US Pharmacopoeia, in a dissolution medium comprised of 1000 ml HCl 0.1N. <??>The invention also provides a process for manufacturing this composition.
Patent PT-1508380-E (PT)
Title: Dosing valve and pump for fluid substances
Inventor: NAVARRO MIGUEL ANGEL MIRA
IPC: B05B11/00
Filed: 2003-05-21
Abstract: The valve comprises three parts of generally cylindrical shape, of two or more diameters, fitted into one another, the first of these having a structure of two successive cylinders, being fixed between the cap of the container carrying the substance to be metered and the rim of the neck of the container itself, while the second part is intended to act as main plunger, sliding by its upper portion inside the first part and having a terminal end of smaller diameter guided in the portion of smaller diameter of the first part and having in its intermediate region a likewise intermediate diameter with the main filling and discharge vents for the product, and the third part is formed by a hollow rod rigidly connected to the handle/outlet nozzle and which likewise has a cylindrical structure with two successive different diameters. <IMAGE>
Patent PT-1695991-E (PT)
Title: Coordination complex of diaminocyclohexaneplatinum(ii) with block copolymer containing poly(carboxylic acid) segment and antitumor agent comprising the same
Inventor: KATAOKA KAZUNORI
IPC: A61K9/107
Filed: 2004-12-08
Abstract: A coordinate complex of diaminocyclohexane platinum (II) with a block copolymer comprising a poly(ethylene glycol) segment and a poly(carboxylic acid) segment is provided. The complex can be effectively used in treatments for tumors, in particular malignant tumors.
Patent PT-1923322-E (PT)
Title: Container closure
Inventor: ZIMMERMANN BERND
IPC: B65D47/06
Filed: 2006-11-17
Abstract: The closure has a retaining ring (10) and a closure cap that is screwed onto a plugging spout of a bellows portion (18). The bellows portion bears a sealing ring, where a flange (13) of the retaining ring engages over the sealing ring. The retaining ring bears a clip (24) with a grip plate (25). The grip plate is arranged in a clip (24) via two connecting sections extending in a radial direction such that the grip plate stays in a distance to a closure cap in the radial direction. A casing base (22) of the closure cap is spaced apart from an underside of the grip plate.
Patent PT-1858864-E (PT)
Title: Stabilized compositions of volatile alkylating agents and methods of using thereof
Inventor: CROOKS PETER
IPC: A61K31/13
Filed: 2006-03-14
Abstract: A composition and method for treatment of cancer. The composition for treating a skin disorder, comprising: a Nitrogen Mustard or an HX salt of the Nitrogen Mustard, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or carrier that does not include petrolatum or ethanol, wherein the non-aqueous vehicle or carrier that does not include petrolatum or ethanol does not include petrolatum or ethanol. The method comprises topically applying the composition of a Nitrogen Mustard or a HX salt of the Nitrogen Mustard to the affected skin, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or carrier that does not include petrolatum or ethanol, wherein the non-aqueous vehicle or carrier does not include petrolatum or ethanol.
Patent PT-2007945-E (PT)
Title: Cellulose-solvent-based lignocellulose fractionation with modest reaction conditions and reagent cycling
Inventor: ZHANG PERCIVAL Y H
IPC: C08H7/00
Filed: 2006-03-29
Abstract: Embodiments of the present invention overcome the well-known recalcitrance of lignocellulosic biomass in an economically viable manner. A process and system are provided for the efficient fractionation of lignocellulosic biomass into cellulose, hemicellulose sugars, lignin, and acetic acid. The cellulose thus obtained is highly amorphous and can be readily converted into glucose using known methods. Fermentable hemicellulose sugars, low-molecular-weight lignin, and purified acetic acid are also major products of the process and system. The modest process conditions and low solvent/solid ratios of some embodiments of the invention imply relatively low capital and processing costs.
Patent PT-2021043-E (PT)
Title: Injectable bone void filler
Inventor: BARRY JOHN J
IPC: A61L27/22
Filed: 2007-04-17
Abstract: The present invention relates to a biodegradable fibrin based composition for injection into osseous defects or voids, which can be the result of osteoporosis, surgery, bone cysts, tumor removal or traumatic bone injury.
Patent PT-2007648-E (PT)
Title: Basket
Inventor: PALAU-RIBES BEATRIZ BORRAS
IPC: B65D5/02
Filed: 2007-04-12
Abstract: The basket of the present invention comprises a lateral surface, a bottom and a handle (12), said basket being formed from at least a sheet provided with a plurality of folding lines, and it is characterized in that said handle extends downwardly into a partition (11) which divides the basket into two housings. Said partition (11) is preferably joined to the bottom of the basket. It is obtained a very light basket, and which occupies a reduced space if transported in its unfolded position, with a great strength and suitable to transport heavy products, such as bottles.
Patent PT-2025810-E (PT)
Title: Railway renewing machine with triple separated spoil
Inventor: KONECNY DIETRICH
IPC: E01B27/10
Filed: 2008-08-15
Abstract: The construction has an excavating chain front (10) which provides a first upper layer of the substructure. A rear digging chain (80) is directed to work behind the front digging chain and arranged below the first upper layer. A second transfer body (70) is arranged in the direction of work after the first injection and compression facility is provided and dumps ballast. A digging chain (30) is arranged between the front and rear of the excavating chain to ensure that between the first upper layer and lower layer an intermediate layer is provided.
Patent PT-2178504-E (PT)
Title: Preservative-free prostaglandin-based ophthalmic solution
Inventor: PILOTAZ FREDERIC
IPC: A61K9/08
Filed: 2008-07-17
Abstract: The present invention provides an ophthalmic solution without an antimicrobial preservative. The solution includes as an active substance at least one prostaglandin and as a solubilizing agent, a surfactant, where the solubilizing agent is polyoxyl-15-hydroxystearate.
Patent PT-2257481-E (PT)
Title: Packaging pouch
Inventor: HEMMERLIN DAVID
IPC: B65D75/58
Filed: 2009-02-19
Abstract: The invention relates to a pouch for containing a product. The pouch comprises a first wall and a second wall which are sealed together in sealed regions. The sealed regions substantially surround a compartment portion within which a product can be located. The pouch includes a tear initiating weakness located away from an edge of the pouch, the tear initiating weakness comprising an elongate weakness which extends along a first axis such that a user can fold the pouch across the tear initiating weakness and initiate a tear from the folded edge substantially along the first axis, the pouch further comprises at least one tear guiding weakness, said tear guiding weakness extending along a second axis transverse to the first axis such that a tear extending substantially along the first axis will meet the at least one tear guiding weakness and be guided along the second axis.
Patent PT-2184059-E (PT)
Title: Potassium-binding polymers for use in a therapeutic or prophylactic method for treating hyperkalemia
Inventor: MONG TONY KWOK-KONG
IPC: A61K9/16
Filed: 2005-03-30
Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
Patent PT-2292249-E (PT)
Title: Non-cytotoxic protein conjugates
Inventor: FOSTER KEITH
IPC: C12N15/62
Filed: 2005-12-01
Abstract: A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described.
Patent PT-547816-E (PT)
Inventor: KENNEY MARYANN CULLY
IPC: D21F7/08
Filed: 1992-12-04
Abstract: The present invention relates to an article of paper machine clothing for use in high temperature applications, which article comprises:-   a) a paper contacting surface layer adapted in use to contact a forming paper sheet;   b) a base layer structure; and c) at least one intermediate layer disposed between said surface layer and said base layer structure, characterised in that said surface layer comprises a fibrous or continuous layer constituting a thermal barrier and providing properties of sheet release.   <IMAGE>
Patent PT-589278-E (PT)
Inventor: IVANOV KOLIO
IPC: H04B7/26
Filed: 1993-09-07
Abstract: In the speed-dependent handover method for hierarchical cell structures described here, it is ascertained whether the mobile stations have passed through the radio coverage area of a microcell within a time interval. If the mobile stations are still in the radio coverage area with respect to the microcell after the time interval, a handover is requested for the relevant mobile stations into the microcell. <IMAGE>
Patent PT-817627-E (PT)
Inventor: RUTHER GERD
IPC: C07D401/14
Filed: 1994-12-14
Abstract: The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2. As isozyme selective inhibitors of beta-1 and beta-2, the compounds are therapeutically useful in treating conditions associated with diabetes mellitus and its complications, as well as other disease states associated with an elevation of the beta-1 and beta-2 isozyme.
Patent PT-731230-E (PT)
Inventor: BLANKE WILLFRIED
IPC: F16K47/12
Filed: 1996-03-01
Abstract: The valve plug (3) between the inlet and outlet is opened and shut by a float, dependent on the level in the cistern. Part of the outlet forms a spiral (38) imparting swirl to the water flowing into the cistern. There can be a filler pipe (27) following the spiral and whose bottom end (28) remains immersed in the water when this is at its lowest level, while the spiral can join on to the pipe inside wall. There can be a throttle following the outlet, formed by a portion of the spiral which is of reduced cross-section. The spiral can be formed between a tapering portion (30) and a mating one with internal thread in the housing into which it screws.
Patent PT-767142-E (PT)
Inventor: TANGHE HANS
IPC: C02F1/52
Filed: 1996-09-20
Abstract: New method to prevent the formation of black marks on the sides of sunken basins contg. water contaminated by copper ions comprises treatment with a metal sulphide with a solubility in water at least equal to that of copper sulphide. Pref. the metal sulphide is a sulphide of Cd, Pb, Co, Ni, Zn, Fe or Mn, pref. Zn. The water in the basin is circulated over a bed of particles contg. the metal sulphide in the presence of a flocculating agent (a mixture of aluminium hydroxide and aluminium chloride). The method is used for basins coated with a water-proof membrane, pref. plasticised PVC.
Patent PT-730871-E (PT)
Inventor: PARK KYOUNG-BAE
IPC: G21G1/02
Filed: 1996-03-08
Abstract: The present invention relates to the radioactive chitosan complex formed by labelling a chitosan, a biocompatible and biodegradable natural polymer, with radionuclide, a radioactive chitosan macroaggregate formed by making chitosan complex into particles, and a kit for preparing radioactive chitosan complex, process for preparation thereof and the use thereof for an internal radiation therapeutic agent. The radioactive chitosan complex and its macroaggregate can be used as an internal radiation therapy for rheumatoid arthritis or cystic cancer such as liver cancer, brain cancer, breast cancer, ovary cancer and the like by administering them directly to the lesion.
Patent PT-839154-E (PT)
Inventor: ANDERSEN RAYMOND
IPC: A61P35/00
Filed: 1996-04-22
Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
Patent PT-897325-E (PT)
Inventor: BOGERT HERMANN
IPC: B05C13/02
Filed: 1997-05-01
Abstract: A method of applying a layer onto a glass container (3) involves using a grab (12) of a manipulator (13) to transport a group (10) of the hot containers (3) to above a coating vessel (18), immerse the group in a coating medium, raise the group and transport the group to above a transport belt (22) where the grab (12) is inactivated to release the group (10) onto the belt (22), the empty grab (12) then being returned to a pick-up point (11) for gripping a new group (10) of containers (3). The novelty is that, after being released from the grab (12), each group (10) of coated containers (3) is transported by the belt (22) through a second curing zone (27) for curing the applied layer. An installation for carrying out the above method has (a) a heating unit (7) for heating the containers (3) to the coating temperature; (b) a manipulator (13) with a grab (12) for picking up and transporting a group (10) of the containers (3) from a pick-up point (11); (c) a grab holder (15) which ca n move along a track of the manipulator (13) and which has a gripper (16) for releasably gripping each container (3) of the group (10); (d) a coating vessel (18) for dip coating of the container group (10); and, as the novel feature, (e) a second curing zone (27), through which each container group is transported by a transport belt (22) for complete or partial curing of the applied layer. Preferably, a first curing zone is provided between the coating vessel (18) and the transport belt (22) for curing the layer on the container bases, the second curing zone (27) being used to harden the rest of the layer. Further claimed is a glass container having, on at least part of its exterior surface, a preferably 30-60 mu m thick layer of thermosetting powder lacquer.
Patent PT-946258-E (PT)
Inventor: EIMER KLAUS
IPC: B01D53/26
Filed: 1997-10-29
Abstract: An advantageous configuration of an adsorption medium in a drying plant is described. At least one cartridge containing the adsorption medium for a gas to be dried is removably disposed in a container of the drying plant. A pressure prevails between the adsorption medium and the cartridge such that the adsorption medium remains stationary in the cartridge, in particular even under changing operating and/or environmental conditions. Using the cartridge enables the adsorption medium to be changed rapidly and safely on site. In addition, the invention ensures a high quality of gas drying, in particular without the added risk of the particles being released. Different cartridges can also be used for different adsorption media and can therefore be optimized to suit the most varied of drying plants.
Patent PT-880971-E (PT)
Inventor: COMOGLIO PAOLO
IPC: A61K38/18
Filed: 1998-05-26
Abstract: The present invention refers to the use of Macrophage Stimulating Protein (MSP) for the preparation of a medicament for the treatment of pathologies of the central and peripheral nervous system of traumatic, infectious or inflammatory origin.
Patent PT-985333-E (PT)
Title: Process for modification of surfaces
Inventor: LARSSON KARL-GUNNAR
IPC: H05K3/18
Filed: 1998-01-27
Abstract: In using a photoinitiator and irradiation with UV-light suitable monomers can be selectively inoculated on the surface of a non conducting substrate in a distinct pattern. Metal ions are thereafter absorbed by these monomers and are reduced. To this pattern further conducting materials, e.g., metals, can thereafter be added in a conventional way. The method according to the invention comprises a fully additive method to produce a circuit board with high resolution and the production of functional components directly on a non conducting substrate.
Patent PT-975349-E (PT)
Inventor: GOLUB LORNE M
IPC: A61P29/00
Filed: 1998-02-26
Abstract: A method for inhibiting the activity of serine proteinase in biological systems includes administering to the system a serine proteinase inhibitory amount of a hydrophobic 4-de(dimethylamino)tetracycline. The method reduces tissue destruction during inflammation resulting from the activity of human leukocyte elastase. The method is used for pharmaceutical and cosmetic purposes.
Patent PT-1014934-E (PT)
Inventor: MARTIN RICHARD
IPC: A61K8/96
Filed: 1998-09-14
Abstract: The invention concerns the use in a cosmetic composition or for preparing a pharmaceutical composition of at least a plant extract of the genus Chrysanthemum for stimulating skin and/or hair pigmentation. The invention also concerns a composition containing at least one active principle and an extract of at least a plant of the genus Chrysanthemum.
Patent PT-1045839-E (PT)
Inventor: HORWELL DAVID CHRISTOPHER
IPC: C07D407/06
Filed: 1998-11-10
Abstract: Novel amines of formulas (1A) and (1B) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammatory diseases, and gastrointestinal disorders, especially IBS. Processes for the preparation and intermediates useful in the preparation are also disclosed. <CHEM> R is sulfonamide, amide, sulfonic acid, or phosphonic acid.
Patent PT-1058609-E (PT)
Title: Method and installation for separating all categories of polymer materials
Inventor: FERAUDY HUGUES DE
IPC: B03B9/06
Filed: 1999-01-22
Abstract: The invention concerns a method for separating all categories of polymer materials derived from waste characterised by successive steps and phases, implemented in the following order: sequentially, a grinding step is followed by a cylindrical drum form factor mechanical separation step, which is followed by a first density separation step in parallel steps, followed by energetic cleaning of the polymer materials and ending with a second density separation step in parallel steps. Said polymer materials can, if required, be extruded. The method enables to obtain different categories of polymer materials, and in particular PE, PP, PS, ABS, PP filled at 20 to 40% with PA, PMMA, Xenoy(TM), PVC.
Patent SG-53991-G (SG)
Title: Electrolytic process for manufacturing pure potassium peroxydiphosphate
IPC: C25B1/28
Filed: 1991-07-09
Abstract: The invention provides a process to manufacture fluoride-free potassium peroxydiphosphate on a commercial scale. The process comprises electrolyzing an alkaline anolyte containing potassium, phosphate, nitrate and hydroxyl ions at a platinum or noble metal anode. The catholyte is separated from the anolyte by a separating means permeable to at least one ion contained in the anolyte or catholyte.
Patent IE-35968-L (IE)
Title: s-TRIAZOLO [4, 3-a] [1, 4] BENZODIAZEPINES
IPC: C07D249/16
Filed: 1972-01-11
Abstract: Cpds of formula (I): (where Q is NR2R3;R1 is H or 1-3C alkyl, R2 and R3 are H, 1-6C alkyl, 2-6C hydroxyalkyl or 7-9C aralkyl, or NR2R3 is 5- to 7- membered polymethyleneimino or morpholino, both opt. substd by lower alkyl and contg. =10C; A is 1-3C alkylene, rings B and C are opt substd by F,Cl,Br,CF3,NO2,1-6C alkyl or alkoxy) and their 5-oxides and acid addn salts are CNS depressants. They may be prepd. by reacting a reactive ester of (I;Q=OH) with R2R3NH or its alkali metal deriv; reacting a 2-X-3-R1-5-Ph-3H-1,4-benzodiazepine with R2R3NACONHNH2 (where X=SH lower alkoxy or alkylthio (opt. activated by a substd) or opt. substd amino); hydrolysis of (I;Q=R2R3'N) (where R3'=acyl) to give (I;Q=R2HN); reaction of (I;Q=phthalimido) with N2H4 and/or strong acid to give (I;Q=NH2); redn of (I;Q=N3) to give (I;Q=NH2); or reaction of (IfQ=R2HN) with a 1-6C satd aliphatic oxo cpd and reducing the product.
[CH544764A]
Patent IE-31818-L (IE)
Title: Reducing axial oscillations in shafting.
IPC: F16F15/10
Filed: 1968-02-13
Abstract: 1,205,174. Vibration dampers. BURMEISTER & WAIN'S MASKIN-OG SKIBSBYGGERI. 13 Feb., 1968 [15 Feb., 1967], No. 6966/68. Heading F2S. [Also in Division F1] Longitudinal oscillations, at least in one axial direction, of a shaft 3 of a piston or turbine engine, are effectively reduced by a substantially rigid connection between the free end of the shaft and the engine bedplate 2. Said connection comprises a cylinder 1 secured to the bedplate 2 and filled with pressure oil through a check valve 7, and a piston 8 secured to the end of the crankshaft 3 via a roller bearing 13. The cylinder is provided with an outlet valve (not shown) which opens when the oil pressure exceeds a predetermined value. The natural frequency of the shafting is thus increased so that the risk of resonance is overcome. In a modification the cylinder is contained in an axial bore in the crank-shaft, which serves as a pressure lubricating duct, the piston being secured to the bedplate, Fig. 2 (not shown). Oscillations may be reduced in both directions if desired.
[GB1205174A]