baber/WOPTO huggingface dataset:
Patent CY-1110577-T1 (CY)
Title: Διαγνωση της νοσου alzheimer με αναλυση πολυμορφισμων γονιδιου il-10
Inventor: CLERICI MARIO
IPC: C12Q1/6883
Filed: 2009-12-09
Abstract: Προτείνεται να ενέχεται μία φλεγμονώδης διεργασία στην παθογένεση της νόσου Alzheimer (AD), μιας νευροεκφυλιστικής διαταραχής που χαρακτηρίζεται από την παρουσία νευριτικών πλακών εντός του εγκεφαλικού φλοιού που κυρίως αποτελούνται από μία μικρή αδιάλυτη πρωτεΐνη 40-42 αμινοξέων (αμυλοειδής πρωτεΐνη). Οι βιολογικές σχέσεις αυτής της διεργασίας εντούτοις δεν είναι σαφείς. Η Ιντερλευκίνη-10 (IL-10) είναι μία κυτοκίνη που καταστέλλει Τ λεμφοκύτταρα και προκαλούμενη από κύτταρο ανοσία στους ανθρώπους και τους ποντικούς και έχει ισχυρές αντι-φλεγμονώδεις ιδιότητες. Για να πιστοποιηθεί εάν η παραγωγή IL-10 μπορεί να είναι εξασθενημένη σε ασθενείς με AD διεγείραμε PBMC από 47 ασθενείς και 25 της ίδιας ηλικίας υγιή δείγματα αναφοράς (HC) με ένα μιτογόνο, ένα αντιγόνο ανάκλησης ή με αμυλοειδή πεπτίδια. Μετρήθηκε επίσης παραγωγή IL-2 στις ίδιες συνθήκες καλλιέργειας. Τα αποτελέσματα έδειξαν ότι αμυλοειδούς-ειδική δημιουργία IL-10 εκλεκτικώς και σημαντικώς μειώνεται σε ασθενείς με AD (p = 0,023). Αναλύσεις επί των αλληλίων του IL-10 γονιδίου απεκάλυψαν ότι ο γονότυπος που συνδυάζεται με υψηλή παραγωγή IL-10 είναι εξαιρετικά σπάνιος σε άτομα με AD (2% έναντι 28%). Η παρουσία χαμηλών/ενδιαμέσων γονότυπων παραγωγής IL-10 (GCC/ATA, ΑΤΑ/ΑΤΑ) συνδυάστηκε με εμφάνιση της ασθένειας σε μία προγενέστερη ηλικία και (ACC/ACC, ACC/ATA) με επιταχυνόμενο ρυθμό προόδου ασθένειας. Αυτά τα δεδομένα έριξαν φως στην βιολογία της φλεγμονώδους διεργασίας που ενέχεται στην παθογένεση της AD δείχνοντας ότι η παρουσία χαμηλών-IL-10-αλληλικών ισόμορφων έχει σαν αποτέλεσμα αμυλοειδούς-ειδική εξασθένιση της παραγωγής IL-10 και συνδυάζεται με την κλινική σοβαρότητα της AD. Αυτά τα αποτελέσματα οδήγησαν να υποστηρίζεται η χρήση αντιφλεγμονωδών ενώσεων στην θεραπεία αυτής της
Patent CY-1113113-T1 (CY)
Inventor: OUTREMAN JEAN-TRISTAN
IPC: B67C7/00
Filed: 2010-07-05
Abstract: The method involves providing a container made of a material in accordance with an extrusion/blowing process following a heat resistant treatment. The container is filled with a hot sterilized liquid and the container is closed immediately after it is filled. The container is allowed to cool below a congealing temperature, for deforming the container by a formation of depression in it. The container is heated to bring relaxation of the residual stresses for reduction and generation of internal pressurization of the container to compensate for the deformations caused by the depression effects.
Patent CY-1112075-T1 (CY)
Inventor: BRADFORD WILLIAMSON ZIEGLER ROSS
IPC: A61P11/00
Filed: 2011-11-22
Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
Patent CY-1114113-T1 (CY)
Title: Συνδυασμος ενος αναστολεα του κολπικου ρευματος if και ενος βητα-αναστολεα
Inventor: LEREBOURS GUY
IPC: A61K31/55
Filed: 2013-07-03
Abstract: Συνδυασμός ενός αναστολέα του κολπικού ρεύματος If και ενός β-αναστολέα, καθώς επίσης οι φαρμακευτικές συνθέσεις που τον περιέχουν.
Patent CY-1115437-T1 (CY)
Title: Υδροξυμεθυλοκυκλοεξυλαμινες
Inventor: FRORMANN SVEN
IPC: A61P25/00
Filed: 2014-08-06
Abstract: Η εφεύρεση αφορά σε ενώσεις, οι οποίες παρουσιάζουν μία χημική συγγένεια προς τον υποδοχέα μ-οπιοειδούς και τον υποδοχέα ORL1, σε μεθόδους για την παρασκευή τους, φάρμακα που περιέχουν τις ενώσεις αυτές και στη χρησιμοποίηση των ενώσεων αυτών για την παρασκευή φαρμάκων.
Patent CY-1118685-T1 (CY)
Title: Περιβλημα εγκλεισμου πολλαπλων χρησεων με ενισχυμενο βαθμο αντοχης
Inventor: BURKE EDWARD J
IPC: H02G9/10
Filed: 2017-03-06
Abstract: Ένα περίβλημα εγκλεισμού πολλαπλών χρήσεων με ενισχυμένο βαθμό αντοχής περιλαμβάνει μια δομή κάθετου τοιχώματος που έχει ένα κατακόρυφο πλαίσιο εσωτερικού τοιχώματος (46) που εκτείνεται από μια άνω άκρη έως μια κάτω άκρη της δομής. Το πλαίσιο εσωτερικού τοιχώματος (46) έχει μια εσωτερική επιφάνεια που εκτείνεται στο εσωτερικό του περιβλήματος εγκλεισμού. Μια ή περισσότερες στενές, κάθετα εκτεινόμενες περιοχές με σχισμές (58) κάνουν εσοχές στην εσωτερική επιφάνεια του πλαισίου τοιχώματος. Κατακόρυφες άκαμπτες ράβδοι στήριξης (60), προαιρετικά προσαρμοσμένες για χρήση ως ικριώματα καλωδίων, τοποθετούνται μέσα και στερεώνονται σταθερά σε ξεχωριστές περιοχές με σχισμές στο πλαίσιο τοιχώματος. Οι ράβδοι στήριξης (60) παρέχουν ένα συνεχόμενο μέσο σταθερής κάθετης στήριξης από την άνω άκρη προς τα κάτω έως την κάτω άκρη της δομής τοιχώματος του περιβλήματος εγκλεισμού. Οι ράβδοι στήριξης με εσοχές, σε συνδυασμό με τη δομή κάθετου τοιχώματος, παρέχουν ενισχυμένη αντοχή τοιχώματος που υπερβαίνει αυτήν των βιομηχανικών προτύπων δοκιμών φορτίου κάθετου πλευρικού τοιχώματος και κεντρικού φορτίου.
Patent CY-1120286-T1 (CY)
Title: Πρωτεϊνες δεσμευσης υποδοχεα προλακτινης και χρησεις αυτων
Inventor: ANDERSON MARK
IPC: C07K16/28
Filed: 2018-05-25
Abstract: Η παρούσα εφεύρεση περιλαμβάνει πρωτεΐνες δέσμευσης PRLR. Συγκεκριμένα, η εφεύρεση σχετίζεται με αντισώματα που είναι χιμαιρικά, CDR μεταμοσχευμένα και ανθρωποποιημένα αντισώματα. Τα προτιμώμενα αντισώματα έχουν υψηλή συγγένεια για τον hPRLR και εξουδετερώνουν την δραστικότητα hPRLR in vitro και in vivo. Ένα αντίσωμα της εφεύρεσης μπορεί να είναι ένα πλήρους μήκους αντίσωμα ή ένα τμήμα δέσμευσης αντιγόνου αυτού. Επίσης παρέχονται μέθοδοι παρασκευής και μέθοδοι χρήσης των αντισωμάτων της εφεύρεσης. Τα αντισώματα, ή τμήματα αντισωμάτων, της εφεύρεσης είναι χρήσιμα για την ανίχνευση hPRLR και για την αναστολή της δραστικότητα του hPRLR, π.χ. σε ένα ανθρώπινο υποκείμενο που πάσχει από μια διαταραχή στην οποία η δραστικότητα του hPRLR είναι επιβλαβής. Επίσης στην εφεύρεση περιλαμβάνονται συζεύγματα φαρμάκων αντισωμάτων αντι-PRLR (ADC).
Patent CY-1123320-T1 (CY)
Title: Ενωση πυραζολοθειαζολης και φαρμακο που την περιλαμβανει
Inventor: SHIBA YOSHINOBU
IPC: C07D513/04
Filed: 2020-09-04
Abstract: Η εφεύρεση παρέχει μία ένωση πυραζολοθειαζόλης τύπου [Ι] ή ένα φαρμακευτικά αποδεκτό άλας αυτής: Η ένωση της εφεύρεσης έχει ανασταλτική δραστικότητα JAK1 και, κατά συνέπεια, ανοσοκατασταλτική δράση, αντιφλεγμονώδη δράση και αντιυπερπλαστική δράση και είναι χρήσιμη στην αγωγή νόσων, για παράδειγμα, ρευματοειδούς αρθρίτιδας, φλεγμονώδους νόσου του εντέρου, ψωρίασης και αγγειίτιδας, βρογχικού άσθματος, χρόνιας αποφρακτικής πνευμονοπάθειας και ηωσινοφιλικής κολπίτιδας, ρινικού πολύποδα.
Patent GR-880300089-T1 (GR)
Title: Composition and process for lastingly reshaping the hair
Inventor: PETER HARTMANN
IPC: A61K8/46
Filed: 1988-10-21
Abstract: Agent for permanent setting of hair based on a thioglycolic acid ester containing cysteamine or its salt, as well as a process for permanent setting of hair with said agent. The latter ensures efficient permanent setting which, at the same time, cares for the hair without curling the ends.
Patent SI-2902039-T1 (SI)
Title: IL-17 antagonistic antibodies
Inventor: DI PADOVA FRANCO E
IPC: C07K16/00
Filed: 2005-08-04
Abstract: An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for us in the treatment of an IL-17 mediated disease or disorder, e.g. rheumatoid arthritis.
Patent SI-2622858-T1 (SI)
Title: Intra smoothing filter for video coding
Inventor: VAN DER AUWERA GEERT
IPC: H04N19/593
Filed: 2011-09-30
Abstract: This disclosure relates to techniques for reducing the amount of additional data encoded with a block encoded using intra-predictive coding. Particularly, the techniques provide apparatus and methods of applying a smoothing filter to prediction samples used in intra-predictive coding. For example, in fixed mode-dependent intra-predictive coding, a video encoder may determine the type of smoothing filter applied to prediction samples based on block size and intra-prediction mode combination associated with the current block, where the combination is used to look up a filter in a first filter table. In adaptive mode-dependent intra-predictive coding, the encoder uses two filters, one from the first filter table and another from a second filter table, applies both filters, and determines which yields better results. When the second filter table filter yields better results, the encoder encodes a filtering indication. When a filter from the first filter table is used, no filtering indication is encoded.
Patent SI-2968442-T1 (SI)
Title: New stable pentadecapeptide salts, a process for preparation thereof, a use thereof in the manufacture of pharmaceutical preparations and a use thereof in therapy
Inventor: RUCMAN RUDOLF
IPC: C07K14/00
Filed: 2013-05-09
Abstract: The present invention discloses new stable pentadecapeptide salts of formula (I): (I) SEQ ID NO 1 Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala 1               5                   10            Gly Leu Val · n BAA         15 wherein n means 1, 2 or 3, and BAA means basic amino acid, a process for the preparation thereof, a process for the use thereof for the manufacture of pharmaceutical formulations in liquid and solid form and a use thereof for prevention, protection in treatment of diseases and disease conditions and for the preparation of formulations for use as food supplements.
Patent TR-200502341-T1 (TR)
Inventor: INAN CEMIL
IPC: F25D17/04
Filed: 2003-12-16
Abstract: This invention relates to a refrigerator comprising one or more doors for one or more compartments, and for one or more compartments between doors.
Patent TR-201111375-T1 (TR)
Title: Bir aerosol yangin söndürme aygiti
Inventor: ZHANG WEIPENG
IPC: A62C5/00
Filed: 2010-06-06
Abstract: Bu buluş, muhafazayı, iç keseyi, aerosol üretici maddeyi ve başlatıcıyı, ve bir hücreli yapıda soğutma katmanını veya bir kimyasal madde ve püskürtme delikleri arasında bir küresel veya düzensiz biçimde soğutucu ile akuple bir hücreli yapı tarafından oluşturulan soğutma katmanını içeren bir aerosol yangın söndürme aygıtı ile ilgilidir . Aygıtta kullanılan hücreli yapı, kısa bir sürede çok fazla ısıyı absorbe edebilen geniş bir ısı değiştirme yüzeyine sahiptir, ve böylece iyi soğutma etkisi sağlar; hücreli yapı düzenli biçimdedir, monte etmesi kolaydır, ve monte edilen aerosol yangın söndürme aygıt boyutta kompakttır, yerden kazandırır, ve kurması kolaydır; ayrıca, hücreli yapı, azot oksit ve karbon monoksit gibi aerosolden üretilen toksik gazları uzaklaştırmak için, bir katalizör malzemeyi kolayca destekleyebilir .
Patent DE-3382742-T2 (DE)
Inventor: ALTON NORMAN K
IPC: C07K16/00
Filed: 1983-04-25
Granted: 1994-07-28
Abstract: There is provided a method for the manufacture of linear, double stranded DNA sequences of a length in excess of about 200 base pairs and coding for expression of a predetermined continuous sequence of amino acids with a selected host microorganism transformed by a selected DNA vector including the sequence, a manufactured, linear, double stranded DNA sequence of a length in excess of about 200 base pairs and coding for the expression of a predetermined continuous sequence of amino acids by a selected host microorganism transformed with a selected DNA vector including the sequence, said sequence characterized by having at least one unique palindromic six base recognition site for restriction endonuclease cleavage at an intermediate position therein, a polypeptide product of the expression by an organism of such a manufactured DNA sequence, a biologically functional DNA microorganism transformation vector including such a manufactured DNA sequence and a reagent material comprising a radio labelled manufactured DNA sequence.
Patent DE-3689888-T2 (DE)
Inventor: SHIKATA HIROAKI
IPC: A61F13/15
Filed: 1986-12-01
Granted: 1994-09-08
Abstract: A disposable diaper (10) having front and rear waist portions and comprising a liquid permeable topsheet (50); a liquid impermeable backsheet (30) affixed to the topsheet; an absorbent core (40) interposed between the topsheet (50) and the backsheet (30); a crotch portion located intermediate the front and rear waist portions; a pair of side flaps; and crotch tensioning means (60) associated with each of the side flaps. The absorbent core (40) has oppositely disposed end portions and a pair of longitudinally disposed side edges therebetween. The crotch tensioning means (60) further comprises one or more elasticized members extending from an attachment area in the crotch portion of the diaper, across the respective side flap, to a location longitudinally outside of the crotch portion. The crotch tensioning means (60) thereby tend to impose outward lateral tension on the crotch portion of the diaper (10) when in use. The attachment areas for such crotch tensioning means (60) are preferably oppositely disposed within the crotch portion of the diaper (10) and are laterally spaced from one another at a width of less than approximately 153 mm. The resulting disposable diaper (10) provides improved aesthetic fit on the wearer and improved containment of voided materials.
Patent DE-3852638-T2 (DE)
Inventor: KENDELL LAMAR
IPC: F16K11/085
Filed: 1988-02-19
Granted: 1995-05-18
Abstract: Bagless continuous ambulatory peritoneal dialysis comprising a valve (12) having first, second and third fluid ports (A, B, C). The first and second fluid ports (A, B) are secured to first and second fluid containers (54, 62) respectively, through tubing (48, 56) and connector assemblies (50, 52, and 58, 60). The third fluid port (C) is connected through tubing (64) to a catheter (70) implanted in the abdominal wall of a user, also through a connector assembly (66, 68). The valve (12) includes an actuator (38) moveable at least between four positions, a first position (fig. 6b) which all of the fluid ports (A, B, C) are blocked, a second position (fig. 6c) in which the second and third fluid ports (B, C) are interconnected, a third position (fig. 6d) in which the first and second fluid ports (A, B) are interconnected, and a fourth position (fig. 6e) in which the first and third fluid ports (A, C) are interconnected. The method employs the valve (12) to provide dialysis by reversing the fluid containers (54, 62) and the direction of movement of the valve actuator (38) for alternate cycles.
Patent DE-3878230-T2 (DE)
Inventor: TAYLOR LAURIE
IPC: H02M7/06
Filed: 1988-03-09
Granted: 1993-05-27
Abstract: A rectifier circuit comprises two Zener diodes (3,4) having substantially the same characteristic Zener voltage which are connected to receive a sinusoidal input signal via a low impedance buffer (8). A half-wave rectified signal appearing on line (17) has a DC bias equal to the Zener voltage which is removed by the operational amplifier (15). A low pass filter (20) provides a smoothed DC voltage output on line (21). The circuit may be used as an AC to DC converter or for the detection of signals ranging from several volts down to a few millivolts. Its linear response over a wide dynamic range and at small signal levels is an advantage over conventional silicon diode rectifier circuits which suffer distortion at low signal levels.
Patent DE-3882634-T2 (DE)
Inventor: MODEL MICHAEL JOHN
IPC: H02J9/06
Filed: 1988-09-09
Granted: 1993-11-11
Abstract: A UPS system includes a mechanical backup input line isolation switch (104) to provide mechanical isolation between a primary energy source connected to the input line (101,102) and a secondary energy source (120) upon detection of a failure of an electronic isolation switch (107) normally providing isolation between the input line and the secondary energy source. Detection of such a failure is accomplished by means of a dummy load (150) which is connected across the input line. Its impedance is sized to permit a small low level of current flow, above normal leakage current levels permitted by a functioning semiconductor electronic line switch, if energy is reverse coupled from the reserve energy source via the failed electronic line switch, without draining significant power from the primary energy source when the UPS is normally operative and deriving power from the primary energy source. A power flow direction sensing circuit (151) detects the direction of power flow at the input to which the primary energy source is connected to the UPS, and a control circuit (152) responsive to the power flow direction sensing circuit disconnects the input from the primary energy source, if reverse power flow is detected, by activating the mechanical switch.
Patent TR-199900096-T2 (TR)
Inventor: DODEY PIERRE
IPC: A61P25/04
Filed: 1997-07-23
Abstract: PCT No. PCT/FR97/01377 Sec. 371 Date Jan. 25, 1999 Sec. 102(e) Date Jan. 25, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/03503 PCT Pub. Date Jan. 29, 1998Compounds selected from the group which consists of the compounds of formula (I), wherein each of X1 and X2 which are the same or different, is halogen or a C1-3 alkoxy group, R1 is H, CF3 or a C1-3 alkyl group, R2 is a hydrogen atom or an OH group, A is group (a), (b) or (c), B is a single bond, -CO-, -CO-CH2-, -CO-CH2-O-, -CO-CH=CH or -SO2-, m is 2 or 3, N is 0, 1, 2 or 3, R3 is a hydrogen atom or a methyl group and W is CH or N, the amidine group C(=NR2)NH2 being in the 2, 3 or 4 position on the aromatic ring, and addition salts thereof, are disclosed. A method for preparing said compounds, and the therapeutical use thereof, particularly for treating diseases in which bradykinin is involved, are also disclosed.
Patent TR-199900951-T2 (TR)
Inventor: COHEN FREDRIC J
IPC: C07D333/56
Filed: 1997-10-29
Abstract: Gögüs kanserinin engellenmesi için bir yöntem olup, bu yöntem, ihtiyaç duyan bir insana, yeterli bir süre için, (I)formülüne sahip olan bir bilesigin ya da farmasötik açidan kabul edilebilir tuzlari ve solvatlarinin etkili bir miktarinin tatbik edilmesini içermektedir.
Patent DE-60003103-T2 (DE)
Inventor: LESIEUR DANIEL
IPC: A61P25/22
Filed: 2000-03-24
Granted: 2004-05-19
Abstract: Compounds (I) selected from alkylenedioxybisnaphthalene derivatives and related compounds are new.  Compounds of formula (I) other than diethyl 2-acetylamino-2-(5-(3-(2-acetylamino-3-ethoxy-2-ethoxycarbonyl-3-oxopr opyl)-1H-indol-5-ylmethyl)-1H-indol-3-ylmethyl)malonate and N-(2-(5-(3-(2-acetylaminoethyl)-1H-indol-5-ylmethyl)-1H-indol-3-yl)eth yl)acetamide are new.  A = NR<1>-C(Q)-R<2>, NR<1>-C(Q)-NR<2>R<3> or C(Q)-NR<2>R<3>;  Q = O or S;  R<1> - R<3> = H or R; or  NR<2>R<3> = 1-piperazinyl, piperidino or pyrrolidino;  R = optionally Q'-substituted 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 3-8C cycloalkyl or (3-8C cycloalkyl)-(1-6C alkyl); 1-6C polyhaloalkyl; or optionally Q-substituted aryl, aryl(1-6C alkyl), aryl(2-6C alkenyl), heteroaryl, heteroaryl-(1-6C alkyl) or heteroaryl-(2-6C alkenyl);  B = NR<1>-C(Q)-R<2>, NR<1>-C(Q)-NR<2>R<3>, C(Q)-NR<2>R<3>, C(Q)-OR<1>, NR<1>-C(Q)-OR<2> or NR<2>R<3>;  G1, G3 = 1-4C alkylene optionally substituted by one or more of OH, COOH, CHO, R, OR, C(O)OR or C(O)R; Cy = a group of formula (i) in which G2 is attached to the benzene ring and G1 or G3 is attached to the other ring, or a group of formula (ii) in which G2 is attached to the D ring and G1 or G3 is attached to the other ring:  X, Y' = S, O, C, CH or CH2;  R<4> = H, halogen, CF3, OH, COOH, CHO, NH2, NHR, NRR', NHC(O)R, C(O)NHR, R, OR, C(O)R or COOR;  R' = R;  Z' = S, O, CH, CH2, NH, NSO2-phenyl or NR; D' = a benzene or pyridine ring;  G2 = an optionally substituted W1(CH2)nW2(CH2)mW3 group containing no adjacent heteroatoms;  W1-W3 = bond, O, S, CH2, CHR, NH or NR;  n, m = 0 - 6;  Q' = one or more of OH, 1-6C alkoxy, 1-6C polyhaloalkyl, NH2, 1-6C alkylamino, di(1-6C alkyl)amino and halogen;  aryl = naphthyl, phenyl or biphenylyl; heteroaryl = a saturated or unsaturated mono- or bicyclic group containing 5-10 C atoms and 1-3 heteroatoms selected from N, S and O; and  Q = OH, COOH, 1-6C alkoxy, 1-6C alkyl, 1-6C polyhaloalkyl, CHO, CN, NO2, NH2, 1-6C alkylamino, di(1-6C alkyl)amino and halogen. Independent claims are also included for the following:  (1) a process for preparing (I); and  (2) compounds of formula (II) other than N-(2-(5-(2-hydroxyethoxy)-1H-indol-3-yl)ethyl)acetamide.  W4 = O, S, NH or NR; and  E' = OH or halogen;  provided that W4-(CH2)n-W2-(CH2)m is not oxyalkylene when Cy is naphthylene and G1-A is (CH2)2-NR<1>CQR<2> or (CH2)2-NR<1>CQNR<2>R<3>.
Patent DE-60003737-T2 (DE)
Inventor: MARRITT WILLIAM A
IPC: C09D11/38
Filed: 2000-03-17
Granted: 2004-02-05
Abstract: The present invention is directed to an aqueous ink composition containing polyoxyalkylenated polyfluoro-isopropylidene glycerol compounds as cosolvents and to a printing method using same. The ink composition can be used in ink jet printing processes, gives reliable printing performance and is rapid drying.
Patent DE-60007484-T2 (DE)
Inventor: GALLETTI PAOLO
IPC: B01F15/00
Filed: 2000-05-31
Granted: 2004-11-25
Abstract: The present invention relates to a mixer for concrete and similar mixtures, of the type provided with a rectangular mixing tank (2), on whose lateral walls (4) the ends of two counter-rotating parallel mixing shafts with horizontal axis are fitted, it being provided that each end of each shaft is coupled with a geared motor (5) of standard size and power located externally on the bearing wall (4) of the tank (2). <IMAGE>
Patent DE-60007938-T2 (DE)
Inventor: WERQUIN JEAN-CLAUDE
IPC: B22D13/02
Filed: 2000-11-02
Granted: 2004-11-04
Abstract: A method for the vertical centrifugal casting of a bimetallic rolling mill roll with an envelope of rapid high carbon steel is characterised in that the casting of the nodular iron core metal is only carried out after the complete solidification of all the eutectic phases in the high carbon steel.
Patent DE-60010506-T2 (DE)
Inventor: SPIVEY CHRISTOPHER
IPC: B01J31/02
Filed: 2000-11-30
Granted: 2004-10-14
Abstract: A chiral catalyst comprising a 3, 4-disubstituted pyridine, or a salt, N functionalised derivative, dimer or oligomer thereof, wherein the 3-substituent is substantially hindered from rotation about the bond (sp<SUP>2</SUP>-sp<SUP>2 </SUP>biaryl axis) linking it to pyridine and the 4-substituent is an aliphatic or aromatic amine linked by a single bond to the pyridine, the pyridine nitrogen being functionalised or unfunctionalised, preferably comprising a compound of formula I wherein Z is a group substantially hindered from rotation about its bond; and each of R<SUP>1 </SUP>and R<SUP>2 </SUP>are independently selected from C<SUB>1-30 </SUB>alkyl, C<SUB>3-30 </SUB>cyclo alkyl and/or C<SUB>3-30 </SUB>aryl, or NR<SUP>1 </SUP>R<SUP>2 </SUP>form a cyclic amine; wherein R<SUP>1 </SUP>and/or R<SUP>2 </SUP>may be optionally substituted and/or include one or more heteroatoms; a composition or support comprising the catalyst; process for the preparation and resolution thereof; process for stereoselective reaction of an optically inactive substrate using the catalyst; and the optically active reaction product thereof.