baber/WOPTO huggingface dataset:
Patent JP-5670608-B2 (JP)
IPC: A61K35/12
Filed: 2000-05-30
Granted: 2015-02-18
Abstract: Methods are described for treating demyelinating diseases in mammals, such as multiple sclerosis in humans, and viral diseases of the central nervous system of humans and domestic animals, such as post-infectious encephalomyelitis, or prophylactically inhibiting the initiation or progression of demyelination in these disease states, using human monoclonal autoantibodies characterized by their ability to bind structures and cells within the central nervous system. In particular, the methods utilize human monoclonal antibodies selected from the group of sHIgM22 (LIM 22), sHIgM46 cbvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7 and MSI 19E5, monomers thereof, active fragments thereof and isolated or synthetic human or humanized autoantibodies having the characteristics of the foregoing. Nucleic acids and DNA molecules encoding the human monoclonal antibodies, or portions thereof, are provided. The invention also extends to the preparation and use of human polyclonal and monoclonal autoantibodies, monomers thereof, active fragments, peptide derivatives and fragments, and analogs, cognates, agonists and the like corresponding materials, and their use in diagnostic and therapeutic applications. For example, the autoantibodies, monomers, fragments, haptens, and peptide equivalents, are useful in the promotion of neural regeneration and neuroprotection, and therapeutic compositions and vaccines containing peptides or antibodies are included and presented.
Patent JP-3469230-B2 (JP)
IPC: H01L21/68
Filed: 2002-07-12
Granted: 2003-11-25
Abstract: PROBLEM TO BE SOLVED: To provide a vacuum treating device that suppresses an increase in the manufacturing cost while coping with an increase in diameter of a sample and, in addition, is not deteriorated in maintainability. SOLUTION: This vacuum treating device has one cassette block and a plurality of vacuum treating blocks. The cassette block has a cassette base on which a cassette housing samples is placed and a first sample transport means which transports the samples. Each vacuum treating block has a load-lock chamber, a vacuum treating chamber in which the samples are treated under a vacuum, and a second sample transport means which transports the samples under a vacuum. The cassette base is arranged in the front section of the vacuum treating device and the first sample transport means is commonly used for transporting samples one by one between a plurality of cassettes arranged in the front section of the treating device and the load-lock chamber of each vacuum treating block.
Patent JP-4043355-B2 (JP)
IPC: H04L12/911
Filed: 2002-12-10
Granted: 2008-02-06
Abstract: A server-load-balancing program for establishing a permanent connection to a server in advance, and requesting the server to execute a processing request received from a client, by using the permanent connection. First, history information indicating conditions of use of at least one permanent connection in each of first time intervals into which each of at least one preceding period is divided is stored. Next, an optimum value of the number of at least one permanent connection to be established in each of second time intervals into which a coming period is divided is determined based on the history information. Then, the at least one permanent connection to the server in each of the second time intervals in the coming period is established so that the number of the at least one permanent connection in each of the second time intervals is equal to the optimum value.
Patent JP-4864273-B2 (JP)
IPC: A61P31/00
Filed: 2001-07-03
Granted: 2012-02-01
Abstract: This invention relates to the use of compounds of general formula (I) wherein, R is selected from methyl, ethyl, <i>n</i>-propyl, <i>iso</i>-propyl, <i>c</i>-propyl, <i>n</i>-butyl, <i>sec</i>.-butyl, <i>iso</i>-butyl, <i>tert</i>.-butyl, <i>c</i>-butyl, <i>n</i>-pentyl, <i>sec</i>.-pentyl, <i>iso</i>-pentyl, <i>tert</i>.pentyl, <i>neo</i>-pentyl, <i>c</i>-pentyl, <i>c</i>-hexyl and <i>c</i>-heptyl; RNa and RNb are the same or different and selected from hydrogen, methyl and ethyl; R2, R3, R5 and R6 are independently selected from hydrogen, methyl, methoxy, thiomethyl, hydroxy, fluoro, chloro, bromo, trifluoromethyl, phenyl and benzyl; n is 1, 2 or 3; R' and R'' are the same or different and selected from methyl, ethyl, <i>n</i>-propyl, <i>iso</i>-propyl, <i>n</i>-butyl, <i>sec</i>.-butyl, and <i>iso</i>-butyl or R' and R'' together form a saturated heterocyclic ring of 5-7 atoms is 1, 2, 3; and pharmaceutically acceptable salts, hydrates and solvates thereof; for the preparation of a medicament for stimulation of transcription factor AP (activator protein)-1; compositions comprising the compounds of formula (I). The invention also comprises the compounds of general formula (I) with the exclusion of compounds wherein R, R' and R'' simultaneously are methyl. The compounds are useful for the treatment of cancer, infection and manic-depressive illness.
Patent JP-4037273-B2 (JP)
IPC: C12N7/00
Filed: 2002-03-07
Granted: 2008-01-23
Abstract: The present invention is directed to the use of a live, recombinant leporipox virus comprising exogenous DNA, which is operably linked to at least one expression control element and which is incorporated in a non-essential region of the virus genome, in the manufacture of a vector vaccine for the treatment and/or prophylaxis of infectious diseases in non-lepori species. The invention furthermore relates to a live, recombinant leporipox virus comprising exogenous DNA operably linked to at least one expression control element and incorporated in a non-essential region of the virus genome characterized in that said exogenous DNA encodes at least one antigen of a non-lepori pathogen. Due to its restricted host-range the recombinant leporipox virus is non-pathogenic in non-susceptible hosts such as non-lepori vertebrates. Vaccination with said recombinant leporipox virus induced an antigen or immunogenic response in the vaccinated non-lepori host even though productive replication of the virus was not observed in the host.
Patent JP-3995599-B2 (JP)
IPC: A61K8/44
Filed: 2002-03-19
Granted: 2007-10-24
Abstract: A hair care composition comprising (i) an oxidant (typically hydrogen peroxide) and (ii) a chelant such as ethylene diamine disuccinic acid (EDDS - trisodium salt), DTPMP, DTPA, DEPTA, EDTA, HEDP, HPPDS etc, wherein the chelant is in an amount sufficient to provide a damage benefit equivalent defined herein is found to have excellent hair damage inhibiting properties. This is advantageous during bleaching, dyeing, perming and other oxidative hair care treatments. The compositions also provide excellent colour evenness and colour fastness.
Patent JP-4146239-B2 (JP)
IPC: C07H21/04
Filed: 2002-03-27
Granted: 2008-09-10
Abstract: The present invention relates to a screening methods, compositions, and kits for detecting for the presence or absence of one or more target analytes, e.g. proteins such as antibodies, in a sample. In particular, the present invention relates to a method that utilizes reporter oligonucleotides as biochemical barcodes for detecting multiple protein structures or other target analytes in one solution.
Patent JP-4264475-B2 (JP)
IPC: H05H1/14
Filed: 2002-04-10
Granted: 2009-05-20
Abstract: The preferred embodiments described herein provide a magnetic mirror plasma source. While the traditional magnetic/electrostatic confinement method is ideal for many applications, some processes are not best served with this arrangement. The preferred embodiments described herein present a new technique to confine electrons ( 3 ) to produce a low pressure, dense plasma directly on a substrate surface ( 75 ). With these preferred embodiments, a combination of electrostatic and mirror magnetic confinement is implemented. The result is a novel plasma source that has unique and important advantages enabling advancements in PECVD, etching, and plasma treatment processes.
Patent JP-4354209-B2 (JP)
IPC: B60R19/22
Filed: 2003-04-24
Granted: 2009-10-28
Abstract: A bumper structure useful for attachment to a front of a vehicle, including an elongated bumper beam (2) having a front face (21) provided with at least one rearwardly depressed portion (4) extending lengthwise of the bumper beam, a compressable energy absorbing foam material (3) extending lengthwise of the bumper beam, and a bumper fascia (1) covering the foam material. The material has a first portion received in the depressed portion and a second portion protruded forwardly from the front face of the bumper beam such that the second portion is compressed in the depressed portion upon receipt of a collision impact. <IMAGE>
Patent JP-4135565-B2 (JP)
IPC: H05K3/34
Filed: 2003-06-06
Granted: 2008-08-20
Abstract: It comprises circuit board 10 with circuit pattern 2 formed by conductive resin paste on resin substrate 1 , surface-mounted type electronic components 30, 40 arranged with electrode terminals with respect to the connecting region of circuit pattern 2 , connecting member 3 formed from conductive resin paste for connecting the connecting region to the electrode terminal, and insulating adhesive 6 for bonding the electronic components 30, 40 and circuit board 10 , which is lower in curing temperature than conductive resin paste and disposed in a space between circuit board 10 and electronic components 30, 40 between connecting regions.
Patent JP-3835553-B2 (JP)
IPC: H03K19/0185
Filed: 2003-06-11
Granted: 2006-10-18
Abstract: In a level shifter, first (M1) and second (M2) PMOS transistors are connected in series between first and second power sources for supplying first high level (VDD) and low level (LVSS) voltages, respectively, and a capacitor (C1) is formed between a contact point of the first (M1) and second (M2) transistors and the second transistor's gate. A third PMOS transistor (M3) is diode-connected and connected between the first and second transistors' gates. When a second low level voltage is input to the first transistor's gate, a second high level voltage is output to the contact point according to an on resistance ratio of the first (M1) and second (M2) transistors. When a first high level voltage is input to the first transistor's gate, the second transistor (M2) is bootstrapped according to the voltage charged to the capacitor (C1) so that a first low level voltage is substantially output to the contact point. Since the level shifter outputs voltages substantially corresponding to voltages (VDD,LVSS) which the first and second power sources supply respectively, a range of the output voltage may be extended. <IMAGE>
Patent JP-4566543-B2 (JP)
IPC: G07D7/04
Filed: 2003-10-10
Granted: 2010-10-20
Abstract: An apparatus for discriminating valuable papers is provided wherein a validation control circuit 56 (i) drives conveyer device 8 to inwardly move bill along passageway 9 when inlet sensor 13 detects bill, (ii) ceases driving of conveyer device 8 to keep bill in the standby position in passageway 9 when trigger sensor 50 detects bill, (iii) drives a release device 42 to shift a guide roller 40 from the contact position to the separated position, (iv) activates a centering device 10 to centralize bill along the longitudinal central axis of passageway 9 , (v) drives release device 42 to return guide roller 40 from the separated position to the contact position, and (vi) again drives conveyer device 8 to further inwardly move bill. When bill is inserted into an inlet 7 , inlet sensor 13 detects bill to immediately drive conveyer device 8 and center bill on conveyer device 8 for smooth inserting, transporting and centering of bill with the reduced number of structural components of the apparatus.
Patent JP-4344234-B2 (JP)
IPC: C07C327/56
Filed: 2002-07-10
Granted: 2009-10-14
Abstract: There is provided a compound of formula (I):   
or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1  to R 6  have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.
Patent JP-4181989-B2 (JP)
IPC: H04R1/34
Filed: 2002-07-22
Granted: 2008-11-19
Abstract: The invention concerns a mobile membrane loudspeaker equipped with a partial closure optimising its radiation. The invention is characterised in that the loudspeaker with mobile diaphragm (19) attached to a rigid frame (15) defining an acoustic emission plane (P) comprises a closure (25) for only one central zone of said emission plane.
Patent JP-4913322-B2 (JP)
IPC: H04W52/02
Filed: 2002-08-15
Granted: 2012-04-11
Abstract: A Method and System for Utilization of an Outer Decoder in a Broadcast Services Communication System is described. An outer decoder and an inner decoder encode a block of information to be transmitted, to improve protection by adding redundancy. The redundancy permits decoding of the information from less than a complete encoded block of information. Consequently, the receiving station determines when sufficient amount of information for successful decoding has been received, and utilizes the time remaining before the next block of information arrives to perform other activities, e.g., hard handoff on a broadcast channel, inter-frequency hard handoff, and other activities. Alternatively, the receiving station can cease reception, thus decrease power consumption. Furthermore, part of the information block may be utilized for transmission of signaling information.
Patent JP-4638147-B2 (JP)
IPC: A61L9/03
Filed: 2002-10-04
Granted: 2011-02-23
Abstract: A fragrance disperser (10) in one form includes a single fan (101) that passes air over a wicked single or double fragrance (102). A second form has the fan (11) reversible to provide two different airstreams (29a, 29b; 60a, 60b) that evaporate respective different fragrances one after the other. Where two fragrances are provided, the evaporation may be by respective electrical heaters. A fragrance source may be formed by two sheets (31, 40; 47, 48) joined together to form two chambers each receiving a respective wick (37a, 37b; 56a, 56b) and having respective exposed wick portions. The source may incorporate a source of electrical power (45). An alternative source (81a, 81b) has a reservoir (82a, 82b) for fragrance and a wick (87a, 87b) located in an air passage (83a, 83b) forming part of the source so that an air flow is guided through the passage past the wick to evaporate fragrance. Where two fragrances are provided, the fragrance sources may be located side-by-side and matching fragrances may have, for example, matching indicia (95, 96) on the sources so that the match can be easily determined visually.
Patent JP-4317453-B2 (JP)
IPC: B29C70/76
Filed: 2002-11-07
Granted: 2009-08-19
Abstract: A method for producing a profiled bead made of a plastic, particularly of a polymer, on a piece, particularly on a window pane. In the method at least a partial portion of an edge region or lateral face region of a surface of the piece is brought into contact with a forming face. The plastic is deposited stuck to at least part of the periphery of a surface of the piece untouched by the forming face and the external dimensions of the profiled bead formed are also defined by the forming face. The forming face is pressed against the edge region or lateral face region of the fixed piece using a flat support, the shape of which can vary under the pressure of a fluid. This then gives a better matching of the forming face to the contour and to any dimensional discrepancies of the piece.
Patent JP-4392246-B2 (JP)
IPC: G01C19/56
Filed: 2003-02-06
Granted: 2009-12-24
Abstract: A micromachined sensor with quadrature suppression comprising: 
a quadrature suppression electrode; and 
a resonator mass positioned adjacent to the quadrature suppression electrode, the resonator mass capable of moving substantially parallel to the quadrature suppression electrode, the resonator mass including a notch formed adjacent to a portion of the quadrature suppression electrode such that a length of the resonator mass that is directly adjacent to the quadrature suppression electrode varies as the resonator mass moves relative to the quadrature suppression electrode, wherein the quadrature suppression electrode is capable of producing a lateral force on the resonator mass that varies based on the length of the resonator mass that is directly adjacent to the quadrature suppression electrode.
Patent JP-4321266-B2 (JP)
IPC: H03K17/00
Filed: 2004-01-08
Granted: 2009-08-26
Abstract: <P>PROBLEM TO BE SOLVED: To solve the problem that a potential of an output signal is reduced just for a potential drop caused by a through current when the through current is cased to flow while an input signal IN is at VSS level.  <P>SOLUTION: A boot strap type inverter circuit 10 comprises an MOS transistor Qp14 for resetting a gate potential of an MOS transistor Qp12 to a VDD potential when a level of the input signal IN changes from the VDD potential to a VSS potential, and while the level of the input signal IN is the VSS potential, the MOS transistor Qp12 is completely turned off, so that the through current is not caused to flow. Furthermore, an MOS transistor Qp13 is provided for precharging the gate potential of the MOS transistor Qp12 to the VSS potential and when the level of the input signal IN is changed from a precharge state to the VDD potential, the MOS transistor Qp12 is completely turned on, so that the VSS potential is extracted as a level of an output signal OUT.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-4207791-B2 (JP)
IPC: H01L23/50
Filed: 2004-02-03
Granted: 2009-01-14
Abstract: <P>PROBLEM TO BE SOLVED: To improve the mountability, heat dissipation performance, and wire bonding of the semiconductor device of a semiconductor apparatus that has the package pattern of a LGA (Land Grid Array) structure using lead frames.  <P>SOLUTION: A semiconductor chip 20 is mounted on a heatsink 30 which has a plate thickness larger than that of inner leads 40 and is cross-shaped in a top view, inside a molding material 10. The semiconductor chip 20 has an overhanging part 21 over the heatsink 30, and respective one ends of the inner leads 40 are arranged apart in opposite to each other under the overhanging part 21. The undersurface of the heatsink 30 and the terminals 41 of the inner leads 40 are exposed to the outside from the undersurface of the molding material 10.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-4726430-B2 (JP)
IPC: F16B5/10
Filed: 2004-04-16
Granted: 2011-07-20
Abstract: Apparatus and methods for attaching wall panels to support structures are disclosed. The apparatus includes a first member (112,212,312) and a second member (114,214,314). The first member (112,212,312) is coupled to the support structure and has a first elongated coupling member. The second member (114,214,314) has a head portion (132) and a base portion (130,230). The head portion (132) has at least one slot (134) disposed therein that is adapted to receive an edge portion (116) of the panel (118). The base portion (130,230) includes a second elongated coupling member that is adapted to be coupled to the first elongated coupling member.
Patent JP-4548030-B2 (JP)
IPC: H01L21/52
Filed: 2004-07-29
Granted: 2010-09-22
Abstract: <P>PROBLEM TO BE SOLVED: To provide a fixed amount of liquid ejecting apparatus which can eject fixed amount of liquid with good accuracy and can prevent liquid sagging and stringiness.  <P>SOLUTION: The fixed amount of liquid ejecting apparatus is provided with a housing chamber 11 for housing liquid, an extrusion piston 15 for extruding liquid housed in the housing chamber to an exhaust port by every predetermined volume, a 1st passage 21 having an ejection nozzle 26 for ejecting the liquid at one end and an opening 25 at a flank, a 2nd passage 19 which connects the opening of the 1st passage with the exhaust port of the housing chamber, an ejection piston 22 which reciprocates in the 1st passage with freely sliding to open/close the opening 25 and to eject whole amount of the liquid in the 1st passage 21 from the ejection nozzle 26 and an ultrasonic wave application means 23 which applies ultrasonic vibration to the ejection nozzle 26 to heighten discreteness of the liquid from the ejection nozzle. Since the ejection piston 22 plays a role of a valve for preventing spillover of the liquid in the housing chamber 11, whole amount of the liquid in the 1st passage 21 can be ejected with accuracy without being influenced by residual amount and viscosity change of the liquid in the housing chamber 11.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-4799856-B2 (JP)
IPC: B66F19/00
Filed: 2004-12-13
Granted: 2011-10-26
Abstract: Apparatus for controlling the lift of at least one large structural object so as to be easily moved in horizontal direction while maintaining the bottom plate of the object horizontal, comprising: a plurality of air-casters each of which has a torus bag; piping for feeding compressed air into the air-caster; flow control valve installed in the piping; a pressure gauge installed in each air-caster for measuring an inner pressure of the torus bag; a lift distance measuring gauge installed in each air-caster for measuring the lifted distance of the air-caster; and a data processing unit for receiving pressure data measured by the pressure gauge and lift distance data measured by the lifted distance measuring gauge and sending a valve opening control signal to the flow control valve based on the pressure data and/or lifted distance data. <IMAGE>
Patent JP-4582636-B2 (JP)
IPC: C09D7/12
Filed: 2003-07-25
Granted: 2010-11-17
Abstract: New mono- and bis-rylenedicarbimidyl-anthraquinone dyes (I) are claimed.  New mono- and bis-rylenedicarbimidyl-anthraquinone dyes are of formula (I). R  =  H or (substituted) 1-30 C alkyl, 5-8 C cycloalkyl or (het)aryl;  R'  =  Br, CN, -NR32 or (substituted) (het)aryloxy, (het)arylthio or 3-18 C alk-1-ynyl;  R3  =  H, 1-18 C alkyl or (substituted) (het)aryl; or  NR32  =  a 5-7-membered heterocyclic group;  X, Y  =  H or together a 6-membered ring attached to a rylene ring system (Ia), in which X corresponds to the -NH- group and Y to the other free bond;  n  =  2, 3, 4 or may also be 1 if X and Y are a (Ia) group; and m  =  0-6. The full definitions are given in the DEFINITIONS (Full Definitions) Field.  Independent claims are also included for methods of preparing asymmetric (I; where X, Y = H) and symmetric and asymmetric (I, where X, Y = a 6-membered ring attached to arylene ring system).
Patent JP-4435688-B2 (JP)
IPC: A61L27/00
Filed: 2003-10-08
Granted: 2010-03-24
Abstract: Techniques and systems for distracting a spinal disc space and supporting adjacent vertebrae are provided. Trial instruments are insertable into the disc space to determine a desired disc space height and to select a corresponding implant. Implants can be also self-distracting and the implant providing the desired disc space height can be implanted in the spinal disc space.