baber/WOPTO huggingface dataset:
Patent NZ-549531-A (NZ)
Title: Improvement in or relating to a docking system with a pair of buoyant arms independently movable at ends remove from dock
Inventor: PETER GULIK FRANCIS
Filed: 2006-08-30
Abstract: A docking system for a boat includes a pair of arms with each arm attached at a near end to a dock, and at or adjacent a remote end to a locating device. The arms are supported in a buoyant manner prior to a boat being docked and at the remote ends are independently movable.
Patent NZ-552409-A (NZ)
Title: New disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
Inventor: SONESSON CLAS
IPC: A61K31/495
Filed: 2005-06-08
Abstract: Disclosed is a compound of Formula 1 wherein R1 is selected from the group consisting of -CN, -OCF3, -OCHF2, -SCF3, -SCHF2, -CF3, F, Cl, -CH3 and -OCH3; R2 is selected from the group consisting of F, Cl, Br, and CH3; R3 is selected from the group consisting of C1-C3- alkyls and allyl, provided that when R1 is CN or CF3, R3 can only be C1-C2 alkyls; or a pharmaceutically acceptable salt thereof. Disclosed are intermediates and the use of a compound of Formula 1 in the manufacture of a pharmaceutically active preparation for treating a disorder of the central nervous system.
Patent NZ-554202-A (NZ)
Title: A unit for after-fermentation, storing, transportation and dispensing of beer
Inventor: MATVEEV VLADIMIR GENNADIEVICH
IPC: C12C11/00
Filed: 2005-05-18
Abstract: The disclosure relates to the food industry. In order to ensure the process temperature conditions of a device for finally fermenting and/or storing and/or transporting and/or dispensing beer is provided with a cooling unit which is embodied in such a way that it cools a liquid supplied to a cooling jacket, is arranged inside a protective housing or outside thereof and is rigidly connected thereto.
Patent NZ-567732-A (NZ)
Title: Portable and stackable plastic multipurpose container
Inventor: NGUY CHANWA
IPC: B65D6/28
Filed: 2005-10-26
Abstract: A portable and stackable plastic multipurpose container is disclosed. The container includes: a base; a curved top having at least two slidable panels; a pair of opposing substantially identical side walls extending perpendicularly from the base; and a front wall and a rear wall each extending from the base. The side walls have a lower portion and a curved upper portion. The curved upper portion has a top side and a bottom side. The top of the container, which has at least two slidable panels, is slidably connected to the side walls. The top, which has at least two slidable panels, is slidably connected to the front and rear walls. The top is slidably positioned to open from the front wall, the rear wall and at least one of the opposing side walls.
Patent NZ-568285-A (NZ)
Title: 2,4,5-triphenyl imidazoline derivatives as inhibitors of the interaction between P53 and MDM2 proteins for use as anticancer agents
Inventor: DING QINGJIE
IPC: C07D401/06
Filed: 2006-11-22
Abstract: Disclosed are 2,4,5-triphenyl imidazoline derivatives of formula (I) and the pharmaceutically acceptable salts and esters thereof and a process for the synthesis of a compound of formula (I), wherein the variables X1 , X2, R1 , R2, R3, R4, R5 and R6 are as described in the specification. These compounds exhibit activity as anticancer agents and are suitable for the treatment or control of cancer, in particular solid tumors, more particularly breast, colon, lung and prostate tumors.
Patent NZ-572207-A (NZ)
Title: Stabilized compositions containing alkaline labile drugs
Inventor: CROWLEY MICHAEL M
IPC: A61K9/20
Filed: 2007-03-22
Abstract: Disclosed is a process for preparing a stabilized bioadhesive hot-melt extruded composition comprising the steps of: § wet or dry granulating at least one water swellable or water soluble alkaline matrix-forming material; at least one acidic component; and optionally one or more antioxidants, one or more hydrophobic polymers, one or more hydrophilic polymers, one or more other excipients, or a combination thereof to form an excipient mixture having a solution pH of 7 or less; § mixing the excipient mixture with an alkaline labile drug to form a bioadhesive thermoplastic hydrophilic composition; and § hot-melt extruding the hydrophilic composition to form the bioadhesive hot-melt extruded composition, wherein the matrix-forming material is thermoplastic, bioadhesive, or both.
Patent NZ-579620-A (NZ)
Title: Cooling of an electrical machine by using an internal heat exchanger to isolate the machine from ambient air
Inventor: ERIKSEN UFFE
IPC: H05K7/20
Filed: 2009-09-11
Abstract: Arrangement for cooling of an electrical machine (1) is disclosed. The electrical machine (1) comprises an outer rotor (2) and an inner stator (3) with an air-gap (8) between the rotor (2) and the stator (3). The stator (3) is constructed from a number of stacked laminate plates (9), the plates (9) having a number of slots (10) to carry metal windings of a stator coil, the slots (10) facing the air gap (8). The laminate-plates (9) are positioned and fixed by a means of structural support and by end-plates (12, 13) in relation to a central-part (14) of the stator (3) to achieve the air-gap (8). A cavity is formed by the end-plates (12, 13), the central-part of the stator (14) and an internal surface (16) of the laminate-plates (9). Within the cavity a fan (18) circulates a gaseous medium within the cavity through openings (19, 20) of the end plates (12, 13) to the air-gap (8), passing the winding heads (11) of the stator coil, and to circulate the gaseous medium from the air-gap (8) through openings in the stacked laminate-plates (9)back into the cavity. The cavity also contains a heat-exchanger (21), which is used to cool down the circulated gaseous medium by exchanging heat with cooler air outside the machine.
Patent NZ-586608-A (NZ)
Title: Shape-memory corrective device for toenail
Inventor: KIM JAE YOUNG
IPC: A61F5/11
Filed: 2007-09-28
Abstract: A corrective device for ingrown toenails and incurvated toenails. The corrective device includes a central member (13) made of a shape-memory alloy; and prefabricated toenail side-engaging parts (15), each being attached to both ends of the central member. The corrective device of the present invention has advantages such as provision of strong corrective force over the entire toenail, convenient use, suitability for long-term use, straight growth of a toenail that will grow after a surgical treatment of the ingrown toenail, and straightening of a curved toenail.
Patent NZ-589316-A (NZ)
Title: Drive assembly suitable for use in a drug delivery device with a rotational position indicator
Inventor: JONES MATHEW
IPC: A61M5/31
Filed: 2009-05-09
Abstract: A drive assembly 1 for use in a drug delivery device comprising a housing 2 having a proximal end 3 and a distal end 4, an axis a extending between the proximal end 3 and the distal end, at least one drive member, a piston rod 6 adapted to be driven along the axis by the drive member, an indicator 5 adapted to provide positional information about a position of the piston rod 6 relative to the proximal end 3, wherein the indicator 5 and the piston rod 6 are configured to convert a movement of the piston rod 6 with respect to the housing 2 into a rotational movement of the indicator 5. The indicator 5 comprises a rotation member 7 configured to convert movement of the piston rod 6 into the rotational movement of the indicator 5 with the indicator 5 being coupleable to the piston rod 6 via the rotation member 7 and wherein at least a part of the rotation member 7 is arranged within the piston rod 6.
Patent NZ-590248-A (NZ)
Title: Foldable sterilisation wrap with two sealed margins
Inventor: CHEN BEN
IPC: A61B19/02
Filed: 2009-01-21
Abstract: 590248 A sterilisation wrap 10A formed from a single sheet of sterilisation material folded about a fold line 18A to form two parts, the wrap 10A having a first margin 38A adjacent to the fold line 18A, a second margin 42A opposite the fold line 18A and adjacent to the first margin 38A, and a third margin 40A adjacent to the second margin 42A and the fold line 18A. The two parts of the wrap 10A are bonded at the first margin 38A and at the second margin 42A but not at the third margin 40A
Patent NZ-597179-A (NZ)
Title: Cuff for air delivery conduit
Inventor: ROW NATHAN JOHN
IPC: A61M16/08
Filed: 2009-09-01
Abstract: 597179 A cuff of an air delivery conduit comprises a first end portion provided to a tube, and a second end portion adapted to engage a tubular connector 102. The second end portion includes a radial sealing lip extending along an edge of its entry opening that provides an internal diameter d1 that is smaller than an external diameter of the tubular connector. The sealing lip is structured to resiliently deform upon engagement with the tubular connector 102 so as to provide a gas tight seal against the tubular connector, and provides a flexible protrusion 331 structured to resiliently deflect from a first position and into a second position within a cut-out 335 of the second end portion.
Patent NZ-597258-A (NZ)
Title: An acoustic positioning system
Inventor: RAIF RAN
IPC: G06F3/043
Filed: 2008-03-14
Abstract: An acoustic positioning system is disclosed. The acoustic positioning system comprises: (a) a receiver comprising at least two microphones; (b) an implement that moves relative to the receiver; and (c) a controller. The receiver comprises at least two microphones that generate a signal in response to ultrasound waves that it receives. At least one microphone is mounted on the receiver so that an outer surface of the microphone at a front side of the microphone is substantially flush with a surface of the receiver adjacent to and surrounding the microphone. A maximum discontinuity between the outer surface of the microphone and the adjacent surface is no more than half a wavelength of the lowest frequency used. The implement that moves relative to the receiver moves on a positioning surface on top of which the receiver rests, and comprises at least one ultrasound transmitter that transmits ultrasound waves to the receiver. The controller uses the signal to track a position of the implement on the positioning surface.
Patent NZ-597620-A (NZ)
Title: A process for the synthesis of naratriptan
Inventor: CHIKHALIKAR SANDIP VASANT
IPC: A61K31/404
Filed: 2010-08-18
Abstract: 597620 Disclosed herein is a process for preparing naratriptan or a salt thereof, the process comprising: (a) reacting a compound of formula (3) with a compound of the formula HCCR wherein Z is a protecting group, Y is a leaving group and R is a trialkyl silyl group, a trialkylstannyl group or a zinc (II) halide, to obtain the compound of formula (4); (b) converting the compound of formula (4) to a compound of formula (5) wherein Z' is hydrogen or a benzyl group; (c) converting the compound of formula (5) to naratriptan; and (d) optionally converting naratriptan to a salt thereof. Also disclosed herein are compounds (3) and (4) and processes for their preparation.
Patent NZ-599968-A (NZ)
Title: Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity
Inventor: YIN OPHELIA
IPC: A61K9/00
Filed: 2010-11-17
Abstract: Disclosed is a regimen for the administration of a pyrimidyl-aminobenzamide of formula (I) wherein the radicals as defined herein, or of a pharmaceutically acceptable salt thereof, for the treatment of proliferative disorders, particularly solid and liquid tumours, and other pathological conditions mediated by the Bcr-Abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-Kit, DDR1 (discoidin domain receptor 1), DDR2 (discoidin domain receptor 2) or PDGF-R (platelet derived growth factor receptor) kinase activity, wherein the pyrimidylaminobenzamide of formula I and, optionally, pharmaceutically acceptable carriers, are dispersed in a fruit preparation. The compound of formula (I) is preferably 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1 H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide also known as nilotinib. The fruit preparation is preferably apple sause.
Patent NZ-600123-A (NZ)
Title: Compressible-coated pharmaceutical compositions and tablets and methods of manufacture
Inventor: VENKATESH GOPI M
IPC: A61K9/16
Filed: 2010-11-23
Abstract: Disclosed is a pharmaceutical composition comprising compressible coated microparticles comprising: a. drug particles comprising a drug and/or a pharmaceutically acceptable salt, ester, polymorph, or solvate therof; b. a modified-release membrane layer, which is a taste-masking layer, as a first layer comprising a water-insoluble polymeric material disposed over the drug particles, wherein said modified release layer is applied for a weight gain from about 20% to about 50% based on the total weight of the compressible-coated microparticles; c. a second membrane layer comprising a water-insoluble polymer in combination with a gastrosoluble pore-forming polymer disposed over said taste-masking layer, wherein said second membrane layer is applied for a weight gain of from about 5% to about 50% by weight based on the total weight of the compressible-coated microparticles, and wherein said first and/or second coating(s) substantially masks the taste of drug particles; and c. a compressible coating layer comprising a non-polymeric sweetener disposed over the modified-release membrane layer.
Patent NZ-600932-A (NZ)
Title: An improved heater for an electrically heated aerosol generating system
Inventor: DUBIEF FLAVIEN
IPC: A24F40/46
Filed: 2010-12-22
Abstract: Disclosed is an electric heater with longitudinal fingers for generating an aerosol in an electronic cigarette. There is provided an electrically heated aerosol generating system for receiving an aerosol-forming substrate. The system comprises at least one electric heater for heating the aerosol-forming substrate to form the aerosol. The heater comprises a heating element of a first cross section electrically connected to a plurality of elongate support elements. Each support element has a cross section greater than the first cross section. At least one of the support elements is integrally formed with the heating element. The aerosol forming substrate is a liquid aerosol-forming substrate, and the system further comprises a liquid storage portion for holding the liquid and a capillary wick in communication with the liquid storage portion. The support elements are secured adjacent the capillary wick and the heating element extends between the support elements and around the capillary wick. Each of the support elements comprises an electrically positive connector or an electrically negative connector. The heating element comprises a sheet of flexible electrically resistive material heating element extending between the support elements.
Patent NZ-601769-A (NZ)
Title: Caffeineless coffee
Inventor: FUJIWARA MASARU
IPC: A23F5/20
Filed: 2011-03-03
Abstract: 601769 The present disclosure aims to provide caffeineless (decaffeinated) coffee that is rich in flavor. Ethyl isovalerate is incorporated in caffeineless coffee beans. The ethyl isovalerate is incorporated in such a way that its proportion is at least 1 ppb and less than 100 ppb relative to the total amount of the coffee beans. The coffee beans may be in the form of fermented coffee beans. Also provided is a caffeineless coffe extract
Patent NZ-602691-A (NZ)
Title: Increasing plant growth by modulating omega-amidase expression in plants
Inventor: UNKEFER PAT J
IPC: C12N15/82
Filed: 2011-02-28
Abstract: Disclosed is a transgenic plant comprising an omega-amidase transgene, wherein the omega-amidase transgene is operably linked to a root-preferred promoter. Also disclosed is a method for increasing nitrogen use efficiency of a plant relative to a wild type or untransformed plant of the same species, comprising: (a) introducing an omega-amidase transgene into the plant, wherein the omega-amidase transgene is operably linked to a root-preferred promoter; (b) expressing the omega-amidase transgene in root tissue of the plant or the progeny of the plant; and (c) selecting a plant having an increased leaf-to-root ratio of 2-oxoglutaramate relative to a plant of the same species that does not comprise an omega-amidase transgene, wherein the increased leaf-to-root ratio of 2-oxoglutaramate results in increased nitrogen use efficiency.
Patent NZ-602818-A (NZ)
Title: Respiratory apparatus
Inventor: BRAMBILLA ENRICO
IPC: A61M16/00
Filed: 2009-01-30
Abstract: 602818 A blower assembly 22 configured to generate a flow of pressurized breathable gas, comprises a housing including a first housing portion 24, second housing portion 34 and a stator portion 40 between the first housing portion 24 and the second housing portion 34, an axial air inlet 26 provided in the first housing portion 24, at least two tangential outlets 28, 30 provided in the housing, a motor 44 supported within the housing, the motor 44 having a shaft that extends from opposite sides of the motor 44, the shaft being generally coincident with an axis of the motor 44 and the axial air inlet 26, a first impeller 36 attached to the shaft on a first side of the motor 44, and a second impeller 42 attached to the shaft on the opposite second side of the motor 44. Rotation of the first and second impellers is configured to cause a flow of air into the axial air inlet to and around the first impeller 36. The stator portion 40 is configured to direct an air flow from the first impeller 36 around the stator 40 and through a central aperture to the second impeller 42. The air flow from the second impeller 42 is directed to fold back within the outer periphery of the housing in the direction towards the motor 44 to the at least two outlets 28, 30 between the first and second impellers.
Patent NZ-620208-A (NZ)
Title: Substituted n-[1-cyano-2-(phenyl)ethyl]-2-azabicyclo[2,2,1]heptane-3-carboxamide inhibitors of cathepsin c
Inventor: RIETHER DORIS
IPC: C07D519/00
Filed: 2012-09-18
Abstract: Disclosed are N-1-cyano-2-(phenyl)ethyl)-2-azabicyclo[2,2,1]heptane-3-carboxamides of formula I, wherein the substituents are as defined in the specification. Also disclosed is the use of compounds of formula I as inhibitors of Cathepsin C and pharmaceutical compositions containing the same for the treatment and/or prevention of respiratory diseases. An example of a compound of formula I is: rac-(1S, 3S,4R,5S)-N-((S)-1-cyano-2-(4’-cyano-3’-fluorobiphenyl-4-yl)ethyl)-5-fluoro-2-azabieyclo[2,2,1]heptane-3-carboxamide
Patent NZ-623326-A (NZ)
Title: Fuel cell actuation mechanism for combustion-powered tool
Inventor: PURPURA JAMES A
IPC: B25C1/08
Filed: 2010-08-31
Abstract: A handheld power tool, specifically a combustion nailer tool (10), including a tool housing (12), a combustion source (14) disposed in the housing (12). The tool has a valve sleeve (24) reciprocating relative to a cylinder head along a longitudinal tool axis (A) between a rest position and a pre- firing position, a fuel cell chamber (34) in the housing (12) in operational proximity to the combustion source (14) and dimensioned for accommodating a fuel cell. It also includes at least one pivot point (56) associated with the fuel cell chamber (34) transverse to the tool axis (A) for facilitating movement of the fuel cell between a non-activated position and an activated position, and at least one actuator (50) pivotable about the pivot point (56) and extending from the pivot point (56) at least to the tool axis (A) for engaging the valve sleeve (24). The apparatus requires a reduced actuation force in order to combat user fatigue.
Patent NZ-626985-A (NZ)
Title: Combination therapy (vemurafenib and a mdm2 inhibitor) for the treatment proliferative disorders
Inventor: HIGGINS BRIAN
IPC: A61P35/00
Filed: 2013-03-18
Abstract: Disclosed herein is a product comprising (i) as a first component vemurafenib (N-(3-{ [5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl} -2,4-difluorophenyl)propane-1-sulfonamide), and (ii) as a second component an MDM2 inhibitor selected from compound (II) ((4S, 5R)-1-[[4-[[4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxy-phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]]-carbonyl]-4-[3-(methylsulfonyl)propyl]-piperazine)) or compound (III) (4-{ [(2R,3S,4R,5S)-4-(4-chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino} -3-methoxy-benzoic acid), or a pharmaceutically acceptable salt thereof, for the sequential or concomitant use in the treatment of proliferative diseases, such as cancer, involving b-Raf V600 mutant positive tumor.
Patent NZ-700642-A (NZ)
Title: Method for preparation of medetomidine with chloroacetone
Inventor: ZARAGOZA DOERWALD FLORENCIO
IPC: C07D233/56
Filed: 2012-11-15
Abstract: The technical problem of the invention relates to a method for the preparation of medetomidine starting from 1-bromo-2,3-dimethylbenzene and chloroacetone. Medetomidine is the compound of formula (XX) and is an alpha2 adrenergic agonist, which is currently being used as a veterinary sedative and analgesic and is evaluated as anesthetic. The solution to the problem involves a method for the preparation of a compound of formula (XX); the method comprises four steps, the four steps are a step (Q1), a step (Q2), a step (N) and a step (M1); compound of formula (XX) is prepared in step (M1); step (M1) comprises a reaction (M1-reac); reaction (M1-reac) is a reaction between a compound of formula (XXI); a reagent (M-reag) and a reagent (M-A) in a solvent (M-solv); reagent (M-reag) is selected from the group consisting of p-toluenesulfonylmethyl isocyanide, trifluoromethanesulfonylmethyl isocyanide, methanesulfonylmethyl isocyanide, benzenesulfonylmethyl isocyanide, and 4-acetamidobenzenesulfonylmethyl isocyanide, or mixtures thereof; reagent (M-A) is selected from the group consisting of ammonia, sulfamic acid, p-toluenesulfonamide, benzenesulfonamide, 4-acetamidobenzenesulfonamide, tritylamine, formamide, urea, urotropine, ethyl carbamate, and acetamide, or mixtures thereof; solvent (M-solv) is selected from the group consisting of N,N-dimethylformamide, C1-6 alkanol, formamide, 1,2-dimethoxyethane, NMP, toluene, acetonitrile, propionitrile, ethyl carbamate, N,N-dimethylacetamide, water, and acetamide, or mixtures thereof; compound of formula (XXI) is prepared in step (N); step (N) comprises a reaction (N-reac); reaction (N-reac) is a reaction of a compound of formula (XXII) with a catalyst (N-cat); catalyst (N-cat) is selected from the group consisting of acetic acid, formic acid, trifluoroacetic acid, methanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, camphorsulfonic acid, HCl, HBr, H2SO4, HNO3, H3PO4, HClO4, BCl3, BBr3, BF3OEt2, BF3SMe2, BF3THF, MgCl2, MgBr2, MgI2, AlCl3, Al(O-C1-4 alkyl)3, SnCl4, TiCl4, Ti(O-C1-4 alkyl)4, ZrCl4, Bi2O3, BiCl3, ZnCl2, PbCl2, FeCl3, ScCl3, NiCl2, Yb(OTf)3, Yb(Cl)3, GaCl3, AlBr3, Ce(OTf)3, LiCl, Cu(BF4)2, Cu(OTf)2, NiBr2(PPh3)2, NiBr2, NiCl2, Pd(OAc)2, PdCl2, PtCl2, InCl3, acidic inorganic solid substance, acidic ion exchange resin, and carbon treated with inorganic acid, or mixtures thereof; step (Q1) comprises a reaction (Q1-reac); reaction (Q1-reac) is a reaction of a compound of formula (XXV) with a reagent (Q1-reag) to provide a reaction product of reaction (Q1-reac); R1 is Br, Cl, or I; reagent (Q1-reag) is selected from the group consisting of lithium, magnesium, aluminum, zinc, calcium, propylmagnesium chloride, propylmagnesium bromide, and butyllithium, or mixtures thereof; step (Q2) comprises a reaction (Q2-reac); reaction (Q2-reac) is a reaction of the reaction product of reaction (Q1-reac) with chloroacetone; compound of formula (XXII) is prepared by the reaction (Q2-reac).