baber/WOPTO huggingface dataset:
Patent CA-3045553-A1 (CA)
Inventor: BHATTA PALLAVI
IPC: C07K16/46
Filed: 2017-12-18
Abstract: The present invention provides a multispecific antibody molecule comprising at least two binding domains each with a variable heavy region VH and a variable light region VL, wherein each binding domain is specific for an antigen and comprises 6 CDRs, characterised in that at least one binding domain comprises a variable heavy region, VHA, having a framework comprising valine at position (5), lysine at position (13), alanine at position (24) and threonine at position (96) with the proviso that CDRH3 in VHA is other than RYYSAMPFAY (SEQ ID NO:29) and a variable light region, VLA, having a framework comprising leucine at position (11) and glutamine at position (103).
Patent CA-3045876-A1 (CA)
Inventor: MIGAUD MARIE EUGENIE
IPC: A61K31/455
Filed: 2017-11-10
Abstract: Il est décrit un riboside d'acide nicotinique de forme cristalline I selon une formule (VIII) qui peut être préparé par un procédé comprend la dissolution du composé ayant une formule (VIII), ou un sel ou solvate de cette dernière, dans un volume de méthanol, l'ajout d'un volume d'acétone, d'un volume égal au volume de méthanol, au composé ayant une formule (VIII), ou un sel ou solvate de cette dernière, dans le volume de méthanol, et la précipitation et l'isolation de la forme cristalline I. Il est également décrit un triacétate de riboside d'acide nicotinique de forme cristalline I selon une formule (X) qui peut être préparé par un procédé semblable.
Patent CA-3052624-A1 (CA)
Title: Chemical formulation and method of fouling control using same
Inventor: JAQUESS PERCY
IPC: B01D3/00
Filed: 2018-02-05
Abstract: A chemical formulation which controls fouling in process units, such as alcohol distillation columns, has at least two non-ionic surfactants, at least one anti-foam agent, at least one alcohol, optionally at least one preservative, and water. The chemical formulation is animal food grade. A method of using the chemical formulation to control fouling in a process unit during ongoing continuous operation also is provided.
Patent CA-3053776-A1 (CA)
Title: Mechanical locking mechanism using shape memory material
Inventor: BILEN JUAN MIGUEL
IPC: F16B1/00
Filed: 2018-02-15
Abstract: A fastening apparatus includes a retaining member comprising a shape memory material configured to transform, responsive to application of a stimulus, from a first solid phase to a second solid phase. The retaining member is disposed within a hole in a body and secured within the hole by phase change which creates an interference fit to secure the retaining member against rotational and axial movement. The hole has a second axial cross-sectional shape. The retaining member has a first axial cross-sectional shape that is preferably either circular or rectangular.
Patent CA-3053792-A1 (CA)
Inventor: NICHOLSON JEFFREY ALLEN
IPC: C10L7/00
Filed: 2019-08-29
Abstract: Ce combustible de remplacement comporte des déchets régénérés de consistance solide et particulaire à température ambiante. Le combustible comprend un composite de brai de pétrole et un poudrage. Le poudrage pénètre dans la surface du brai. Le poudrage comporte des cendres recyclées, du charbon pulvérisé ou du coke de pétrole pulvérisé.
Patent CA-3054855-A1 (CA)
Inventor: KLOIBER-MAITZ MONIKA
IPC: A01H1/08
Filed: 2018-02-28
Abstract: The invention relates to Sorghum bicolor plants which, due to modifications to the genome relating to a pollen-specific expression of patatin phospholipase, are capable of inducing haploidy, thereby producing haploid progeny, and within short time inbred lines, i.e. homozygous paternal parent and maternal parent lines can be produced by way of chromosome duplication for hybrid breeding. The invention also relates to methods for producing transgenic and non-transgenic plant haploid inducers and for improving the induction power of plants.
Patent CA-3055605-A1 (CA)
Inventor: ANTONIOLI HILARY C
IPC: G01M3/26
Filed: 2018-03-21
Abstract: A pressure monitoring device is provided for use with a tool such as a medical endoscope. The device includes a housing which is fluidically coupled with an internal volume of the endoscope. A pump is used to change the pressure inside the device housing and endoscope, thereby establishing a pressure differential from the ambient environment. During an endoscopy procedure, the pressure inside the device housing is monitored, and a change in pressure exceeding a predefined limit causes an alarm signal indicating a leak has occurred in the endoscope. The device housing may be directly mounted to the endoscope, located remotely and connected with a coupling tube, or integrated with an accessory device connected to the endoscope. The pump may be integrated internally to the device housing, or it may be a separate external pump which is connected to the housing. The pressure differential may be positive or negative relative to ambient.
Patent CA-3056027-A1 (CA)
Title: Derives d'imidazo [4,5-c] quinoleine substitues cycliques
Inventor: CHAPPIE THOMAS ALLEN
IPC: C07D471/04
Filed: 2018-03-01
Abstract: La présente invention concerne de nouveaux dérivés d'imidazo[4,5- c]quinoléine substitués cycliques de formule I, et des sels pharmaceutiquement acceptables de ceux-ci. Dans la formule R1, R2, R4, R5, R6, X et Z sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques comprenant les composés représentés par la formule I et l'utilisation de ces composés dans le traitement de maladies associées à LRRK2, telles que les maladies neurodégénératives, notamment la maladie de Parkinson ou la maladie d'Alzheimer, le cancer, la maladie de Crohn ou la lèpre.
Patent CA-3059127-A1 (CA)
Title: Method for determining a representative parameter of a porous sample and related assembly
Inventor: FAURISSOUX PIERRE
IPC: G01V3/02
Filed: 2017-04-21
Abstract: The method comprises the following steps: - providing a porous sample (10) containing a first fluid; - establishing a steady state profile of a second fluid content in the porous sample (10) by applying a first mechanical load, to create a plurality of regions (17) having different second fluid contents in the porous sample (10); - measuring, in each of the plurality of regions (17), a local saturation in the first fluid or/and in the second fluid; - measuring, in each of the plurality of regions (17), a corresponding local electrical resistivity and/or conductivity; - determining a value of the representative parameter based on the corresponding values of local saturation and of local electrical conductivity and/or resistivity in each of the plurality of regions (17).
Patent CA-3061068-A1 (CA)
Inventor: ENGEL GORD
IPC: A01C7/08
Filed: 2019-11-07
Abstract: A method, system and an apparatus minimize over-seeding and disruption of previously placed seed in an overlap area, when applying an agricultural product to a field with an agricultural product delivery arrangement having row units, by dispensing a predetermined first product amount equal to one hundred percent of a desired application to the field in a first pass through the entire field including the overlap area, and then dispensing a second product amount in a subsequent pass through the overlap area without raising row units out of the soil during the subsequent pass. The second product amount is determined as a function of a percentage the predetermined first product amount applied to the overlap area during the first pass that is disturbed by operative engagement of the row units with the soil during the subsequent pass over the overlap area.
Patent CA-3061927-A1 (CA)
Inventor: SIROIS YANNICK
IPC: F24H4/00
Filed: 2019-11-19
Abstract: A heat exchanger for thermally conditioning a fluid medium comprises a reservoir defining an outer surface and an opposite inner surface defining a cavity for the fluid medium to circulate therein. Inlet and outlet ports are in fluid communication with the cavity for respectively providing the fluid medium to flow in and out of the cavity. A helicoidal coil conduit is positioned within the cavity about the inner surface, circumscribing an area of the cavity, and providing for thermally conditioning the fluid medium when in contact therewith. An obstacle extends along its length within the area and defines a contiguous obstacle surface that is spaced apart from the reservoir inner surface for providing a distance therebetween that increases along the length of the obstacle. The obstacle provides for fluid medium in the cavity to circulate about its surface and along its length.
Patent CA-3062140-A1 (CA)
Inventor: GOYAL SACHIT
IPC: C09D175/08
Filed: 2018-03-21
Abstract: Cette invention concerne un article revêtu, tel qu'un agent de soutènement, comprenant un substrat de base et un ou plusieurs revêtements à base de polyuréthane sur une surface externe du substrat de base. Le ou les revêtements à base de polyuréthane comprennent le produit de réaction d'un composant isocyanate ayant au moins un isocyanate et d'un composant réactif à l'isocyanate qui a un ou plusieurs polyols simples et un ou plusieurs monols de polyéther à un rapport de 1:18 à 18:1. L'indice d'isocyanate est supérieur à 0,2 et inférieur à 1,0.
Patent CA-3063511-A1 (CA)
Inventor: HURKES NATASCHA
IPC: B29C64/165
Filed: 2018-06-05
Abstract: L'invention concerne un procédé de fabrication de corps façonnés stratifiés en trois dimensions par superposition de couches au moyen d'un composant résine contenant au moins une résine furannique et de 5 % en poids à 50 % en poids d'alcool furfurylique monomère et au moyen d'un acide. Les corps façonnés fabriqués par ce procédé peuvent être utilisés notamment comme moules et noyaux de coulée pour la coulée de métaux.
Patent CA-3063890-A1 (CA)
Title: Electronic braking system for an implement
Inventor: THOMPSON DENNIS GEORGE
IPC: B60T7/20
Filed: 2019-12-05
Abstract: An agricultural implement is provided. The agricultural implement includes a braking system configured to slow or stop the agricultural implement. The agricultural implement also includes a hitch configured to couple the agricultural implement to a towing vehicle. The agricultural implement further includes an electronic sensor disposed on the hitch and configured to sense tension and compression forces.  The agricultural implement further includes a controller configured to automatically actuate or disengage the braking system in response to a signal indicating a presence of compression or tension forces from the electronic sensor.
Patent CA-3064953-A1 (CA)
Title: Compositions stabilisees pour l'administration controlee de probiotiques et leurs procedes de production
Inventor: IVANJESKU MARYANNE MAYA
IPC: A61K35/741
Filed: 2018-05-25
Abstract: Une composition stabilisée pour l'administration contrôlée de probiotiques comprend une solution aqueuse de cristalloïdes et de colloïdes constitués de polymères insolubles dans l'eau ayant la capacité de se dégonfler sous charge électrique. La composition comprend aussi une pluralité de gouttelettes d'huile et une solution de base. La composition comprend également une solution déstabilisatrice comprenant un solvant, de l'azote, un acide naturel suffisant pour produire un pH d'environ 3,0 à environ 4,5, et une quantité suffisante d'un sel pour contribuer à une osmolalité entre environ 190 mOsm/L et environ 900 mOsm/L. La composition comprend en outre une pluralité de billes probiotiques microencapsulées, la pluralité de billes probiotiques microencapsulées comprenant entre environ 0,01 % et environ 20 % de la composition en poids.
Patent CA-3067295-A1 (CA)
Title: Anti-carbamylated protein antibodies and the risk for arthritis
Inventor: TROUW LEENDERT ADRIANUS
IPC: G01N33/564
Filed: 2012-02-01
Abstract: Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. The present invention provides means and methods for determining antibodies against homocitrulline containing proteins or carbamylated proteins/peptides (anti-Car P) for the classification of individuals suffering from or at risk of suffering from arthritis.
Patent CA-3068151-A1 (CA)
Title: Systems and methods for filtering noise and analyzing venous waveform signals
Inventor: HANDLER JONATHAN
IPC: A61B5/0215
Filed: 2018-06-29
Abstract: Devices, systems, and methods for filtering medical device noise artifacts from venous waveform signals are disclosed. A peripheral venous pressure (PVP) is measured and transformed from the time domain to the frequency domain for analysis to determine patient status. To avoid artifacts of the pumping, the time-domain PVP measurements are filtered to generate a filtered time-domain PVP signal by removing active pumping periods. The filtered time-domain PVP signal is transformed into a frequency-domain PVP signal, which is analyzed based upon peaks indicating respiratory rate, heart rate, or harmonics thereof. A metric of patient status is then determined from the peaks or corresponding frequencies. The patient status may be related to blood volume of the patient and may be used to control pump operation.
Patent CA-3072220-A1 (CA)
Title: Temperature control device for fluids
Inventor: TUNG SHANGWEI
IPC: F24F12/00
Filed: 2020-02-12
Abstract: The present application provides a temperature control device for fluids, which comprises a furnace, a fluid pipe, a plurality of regenerative members, a burner, and an air control device. The burner heats the furnace to store heat to the regenerative members inside the furnace and conduct the thermal energy to the fluid pipe. The fluid pipi outputs a heated liquid.  In addition, the regenerative members further produce and transport heated air to the air control device. The air control device converts the heated air to output cooled air.
Patent CA-3077127-A1 (CA)
Title: Mold device and method for manufacturing resin molded article
Inventor: UCHI TOMOYUKI
IPC: B29C45/44
Filed: 2018-09-20
Abstract: This mold device has a rotary core that rotates about a shaft member as a rotation center by being provided with a rotational driving force directly from a rotation driving means. A restriction core is interposed between the rotary core and a mold body to restrict the rotation of the rotary core.  That is, the rotary core becomes rotatable when the restriction core is withdrawn from between the rotary core and the mold body.
Patent CA-3078655-A1 (CA)
Title: Parking space service and management system and method based on parking space state information
Inventor: XU YIJUN
IPC: G06Q10/02
Filed: 2018-08-31
Abstract: A parking space service and management system based on parking space state information, comprising a cloud server (1), as well as an administrator terminal (2), a driver terminal (3), a vehicle detection module (4), a field terminal assembly (5), and a parking law enforcement terminal (6) connected to the cloud server (1). The cloud server (1) is used for receiving, storing, processing and updating parking space state information. The parking space state information comprises a parking space code, a parking space state, and state change time, and is mainly determined by the state of the vehicle detection module (4), the parking space information, parking space reservation information, and check-in/check-out information. The parking space state comprises states of parking space occupancy, an idle parking space, a special parking space and the like. By means of the system, on the basis of timely, complete and accurate parking space state information, when an abnormal parking space state is discovered, a parking lot administrator is prompted to process and correct the state in time so as to avoid misguiding and wrong occupation; by means of an economic, effective and legal reporting and law enforcement programs, illegal parking is processed, and parking service and management demands of reserved parking, instant parking and parking space sharing are satisfied.
Patent CA-3079934-A1 (CA)
Title: Systeme de positionnement, systeme de communication et procede
Inventor: SHARP DAVID
IPC: G01S5/10
Filed: 2018-12-20
Abstract: La présente invention concerne un dispositif pour déterminer sa position dans un système de communication. En particulier, le dispositif fournit une solution évolutive qui permet d'utiliser un certain nombre de dispositifs dans une zone sans nuire à la précision ni à la latence de la détermination de position. En particulier, le dispositif est agencé pour fonctionner dans un système de communication, le système de communication comprenant une première station de base et une seconde station de base. La première station de base est agencée pour transmettre un premier signal à la seconde station de base et la seconde station de base est agencée pour recevoir le premier signal et transmettre un deuxième signal à la première station de base en réponse au premier signal. De plus, la première station de base est agencée pour recevoir le deuxième signal et transmettre un troisième signal à la seconde station de base en réponse au deuxième signal. Le dispositif comprend une unité de réception agencée pour recevoir le premier signal et le troisième signal provenant de la première station de base et du deuxième signal provenant de la seconde station de base. Le dispositif comprend en outre une unité de mesure de temps de retard agencée pour mesurer un premier temps de retard correspondant au temps écoulé entre la réception du premier signal provenant de la première station de base et la réception du deuxième signal provenant de la seconde station de base. Une unité de mesure de temps aller-retour est agencée pour mesurer un premier temps aller-retour correspondant au temps écoulé entre la réception du deuxième signal provenant de la seconde station de base et la réception du troisième signal provenant de la première station de base. Une unité de synchronisation de la station de base est agencée pour déterminer un second temps d'aller-retour et un second temps de retard à partir d'au moins un signal reçu et une unité de calcul est agencée pour calculer une première différence de temps d'arrivée sur la base du premier temps d'aller-retour, un premier temps de retard, un second temps d'aller-retour et un second temps de retard.
Patent CA-3080716-A1 (CA)
Inventor: ANDERSON ROBERT P
IPC: A61P1/00
Filed: 2018-10-30
Abstract: Provided herein are compositions and methods for treating subjects with Celiac disease, e.g., specific dosages and dosage schedules of a composition comprising at least gluten peptide for use in treating subjects with Celiac disease.
Patent CA-3085055-A1 (CA)
Inventor: TUCKER JEREMY
IPC: G06F16/16
Filed: 2018-11-30
Abstract: L'invention concerne un système de gestion de données couplé à un système de fichiers (16) et à au moins une cible de stockage de données (17), le système comprenant : un processeur configuré pour exécuter des instructions ; une mémoire stockant des instructions qui, lorsqu'elles sont exécutées par le processeur, amènent le processeur à : recevoir une pluralité d'instructions d'opération en provenance du système de fichiers (16) ; générer une pluralité d'événements légers, chaque événement léger (LWE) correspondant à une instruction d'opération de la pluralité d'instructions d'opération ; traiter chaque événement léger par accomplissement de l'instruction d'opération qui correspond à l'événement léger afin d'effectuer une opération sur des données stockées par la ou les cibles de stockage de données (17) ; et fournir au moins une notification de réponse au système de fichiers (16), la ou les notifications de réponse indiquant un état de traitement pour un ou plusieurs des événements légers de manière que le système de gestion de données puisse surveiller chaque opération à mesure qu'elle est effectuée sur des données stockées par la ou les cibles de stockage de données (17).
Patent CA-3086882-A1 (CA)
Title: User terminal and radio communication method
Inventor: TAKEDA KAZUKI
IPC: H04W28/04
Filed: 2017-12-27
Abstract: In order to suppress a decrease in communication throughput and the like even when multiplexing of uplink control information with respect to an uplink data channel is supported, a user equipment according to an aspect of the present disclosure comprises: a transmission unit that multiplexes and transmits an acknowledgment signal onto a first uplink shared channel for performing transmission on the basis of downlink control information with a UL transmission instruction from a radio base station, and/or onto a second uplink shared channel for performing transmission independently of the downlink control information with the UL transmission instruction; and a control unit that determines, on the basis of different information, the number of bits of the acknowledgement signal that is to be multiplexed in the first uplink shared channel and the number of bits of the acknowledgement signal that is to be multiplexed in the second uplink shared channel.
Patent CA-3087049-A1 (CA)
Title: Procedes et appareil pour generer un spectre d'emission acoustique par demodulation chirp
Inventor: DAHME BRET ANTHONY
IPC: G01N29/44
Filed: 2018-12-05
Abstract: La présente invention concerne des procédés, un appareil, et des articles manufacturés. Un appareil donné à titre d'exemple comprend un pré-amplificateur pour conditionner un signal d'émission acoustique en fonction d'une source d'émission acoustique, un démodulateur pour générer des données d'émission acoustique démodulées qui combine le signal d'émission acoustique avec un signal chirpé, et un émetteur pour transmettre les données d'émission acoustique démodulées à un système d'acquisition de données.
Patent CA-3087488-A1 (CA)
Inventor: VILLA ALESSANDRA
IPC: A61P35/00
Filed: 2019-02-08
Abstract: The present invention relates to compositions comprising an IL-12 protein having a first and second subunit, an EDB-binding domain, and a linker between the IL-12 protein and the EDB- binding domain.
Patent CA-3087707-A1 (CA)
Inventor: ANDERSON CHARLES
IPC: A61N2/00
Filed: 2019-01-08
Abstract: The present invention provides, inter alia, apparatus and systems for generating multiple H-fields to additively combine and control deep E-field generation resulting in clinically acceptable centralized heating, and methods for inducing locoregional hyperthermia in a subject using the same. The methods, systems and apparatus disclosed herein provide improved hyperthermia treatment to subjects in need thereof, such as, for example, subjects suffering from cancer.
Patent CA-3088062-A1 (CA)
Inventor: PILLARD ROMAIN
IPC: H01R13/64
Filed: 2019-01-11
Abstract: The invention relates to a socket (10) comprising a fixed element (28), a disc (22) having through-holes (22C) for the passage of pins (54) of a plug connector (50), the disc (22) being rotatable about the axial direction (X) with respect to the fixed element (28) between a protecting position and a connecting position, and an open/close element (34) that is rotatable about the axial direction (X) with respect to the fixed element (28) and with respect to the disc (22) between a closing position, in which the open/close element (34) closes at least one hole (22C) in the disc (22) when the disc (22) is in the protecting position, and an opening position, in which the open/close element (34) opens up the at least one hole (22C) when the disc (22) is in the connecting position.
Patent CA-3088492-A1 (CA)
Title: Device and method for breaking up a body stone
Inventor: BIONDA PIERRE-ALAIN
IPC: A61B17/22
Filed: 2019-01-18
Abstract: The invention relates to a device (100) for the fragmentation of a calculus, comprising: a probe (20) and a drive unit (40) for deflecting the probe (20) along the longitudinal extension (LE) thereof, the drive unit (40) comprising a first drive element (41) for periodically deflecting the probe (20) and a second drive element (42) for the pulsed deflection of the probe (20), the drive unit (40) being designed such that periodic deflection and pulsed deflection can be superimposed.