baber/WOPTO huggingface dataset:
Patent AU-2017414703-A1 (AU)
Title: Transgenic macrophages, chimeric antigen receptors, and associated methods
Inventor: O'NEILL KIM
IPC: A61K39/00
Filed: 2017-05-17
Abstract: Described herein are chimeric receptors. Chimeric receptors comprise a cytoplasmic domain; a transmembrane domain; and an extracellular domain. In embodiments, the cytoplasmic domain comprises a cyptoplasmic portion of a receptor that when activated polarizes a macrophage. In further embodiments, a wild-type protein comprising the cytoplasmic portion does not comprise the extracellular domain of the chimeric receptor. In embodiments, the binding of a ligand to the extracellular domain of the chimeric receptor activates the intracellular portion of the chimeric receptor. Activation of the intracellular portion of the chimeric receptor may polarize the macrophage into an M1 or M2 macrophage.
Patent AU-2017423439-A1 (AU)
Title: Improved routing system
Inventor: BECKMANN CLEMENS
IPC: G06Q10/04
Filed: 2017-07-12
Abstract: A method (300; 400) for routing is disclosed, performed by one or more apparatuses (4; 20), the method comprising obtaining (301; 401) information on a plurality of to-be-transported entities (TBTEs) (3) that are each associated with a respective pick-up position and a respective drop-off position; determining (302; 402), for the plurality of TBTEs (3) and based on routing information, a set of one or more transport routes (TRs), each of the TRs of the set of TRs associated with a respective transport entity (TE) (2) and defining a respective sequence of waypoints, wherein the set of TRs is determined to at least fulfil a criterion that, for each of the TBTEs (3) of the plurality of TBTEs (3), the pick-up position and drop-off position are associated with respective waypoints of the same respective TR of the set of TRs or the pick-up position is associated with a respective waypoint of one TR of the set of TRs and the drop-off position is associated with a respective waypoint of another TR of the set of TRs that is directly connected or connected via one or more other TRs of the set of TRs with the one TR; and providing (303; 403) respective representations of at least a part of the TRs of the set of one or more TRs to the respective TEs (2) associated with the TRs of the set of TRs or to respective devices (200c, 20d) associated with the respective TEs (2), in particular to cause that the TEs (2) follow or are operated, by respective operators, to follow the respective TRs of the set of TRs. According apparatuses, systems and computer programs are also disclosed.
Patent AU-2017431122-A1 (AU)
Title: Dendritic cell potency assay
Inventor: SCHENDEL DOLORES
IPC: C12N5/0784
Filed: 2017-09-05
Abstract: The present invention relates to a method for determining the potency of DCs, comprising the steps: stimulating dendritic cells by incubation with soluble CD40L and TLR7/8 agonist, measuring the secretion of the marker proteins IL-10 and IL-12 from the stimulated dendritic cells. Thereby it can be determined whether the dendritic cell have a high capability to activate T-cells and Natural Killer (NK) cells. The invention also encompasses a method for stimulating dendritic cells comprising the step of stimulating the dendritic cells with soluble CD40L and TLR7/8 agonist.
Patent WO-2018157198-A1 (WO)
Title: Boulon d'ancrage
Inventor: HOWELL STEPHEN
IPC: E21D20/00
Filed: 2018-02-23
Abstract: L'invention porte sur un boulon d'ancrage destiné à être utilisé comme boulon de roche ou boulon à friction dans un trou d'alésage formé dans un corps de roche. Le boulon d'ancrage comprend un élément porteur de charge allongé ayant des première et seconde extrémités opposées, un ancrage étant supporté à proximité de la première extrémité. L'ancrage a une partie déviable pouvant être déviée vers l'extérieur à partir de l'élément porteur de charge. Un manchon entoure l'élément porteur de charge entre l'ancrage et la seconde extrémité, le manchon étant espacé de la première extrémité formant un espace axial entre le manchon et l'ancrage. Un agencement de déviation formé sur le manchon est configuré pour dévier la partie déviable de l'ancrage. L'élément porteur de charge est axialement mobile à l'intérieur du manchon de sorte qu'en cours d'utilisation, l'ancrage peut traverser l'espace pour mettre la partie déviable en contact avec l'agencement de déviation pour provoquer la déviation de la partie déviable.
Patent WO-2018161115-A1 (WO)
Title: Système de coffrage
Inventor: DARWELL STEPHEN W
IPC: E04B2/84
Filed: 2018-03-06
Abstract: L'invention porte sur un système de coffrage (100) qui comprend des premier (102a) et second (102b) composants de coffrage de construction qui sont reliés par un connecteur de coffrage de construction (104). Le connecteur (104) comprend une partie mobile (128) qui peut être déplacée d'une position fermée à une position ouverte. Dans la position fermée, une ou plusieurs parois latérales du connecteur (104) définissent une cavité (144) pour la réception d'un matériau cimentaire. La cavité (144) du connecteur (104) est située par rapport aux cavités (110) des premier (102a) et second (102b) éléments de coffrage. Dans la position ouverte, l'accès est fourni à la cavité (144) du connecteur (104).
Patent AU-2018227081-A1 (AU)
Title: Surface reactivation treatment
Inventor: BATEMAN STUART ARTHUR
IPC: C09D1/00
Filed: 2018-02-27
Abstract: The present disclosure relates to a method of reactivating the surface of an organic paint coating, a method of facilitating adhesion of a further coating to the organic paint coating, and a substrate having a reactivated organic paint coating. There is also disclosed a surface reactivation treatment for an organic paint coating. The reactivation method also facilitates adhesion of the organic paint coating to further coating(s) across a broad application window.
Patent AU-2018231082-A1 (AU)
Title: Half-cell electrochemical configurations for self-cleaning electrochlorination devices
Inventor: SHAW MICHAEL J
IPC: H01M10/0568
Filed: 2018-03-06
Abstract: An electrochemical cell including a first chamber having an anode, a second chamber having a cathode, at least one ionic connection between the first chamber and the second chamber, such that liquid electrolyte from the first chamber is prevented from mixing with liquid electrolyte in the second chamber is provided. The first chamber and the second chamber can be arranged in parallel and positioned remotely from each other. An electrochemical system including the electrochemical cell, and first and second sources of saline aqueous solutions is also provided. Water treatment systems are also provided. A method of operating an electrochemical cell including introducing first and second saline aqueous solutions into first and second chambers of the electrochemical cell, and applying a current across the anode and the cathode to generate first and second products, respectively is also provided. A method of facilitating operation of an electrochemical cell is also provided.
Patent AU-2018237198-A1 (AU)
Title: Botulinum neurotoxins for use in therapy
Inventor: ABUSHAKRA SAWSAN
IPC: C07K14/33
Filed: 2018-03-22
Abstract: Disclosed herein are compositions and methods for use in therapeutic procedures. Use of a "fast-acting" botulinum toxin for cosmetic treatment and/or to prevent or reduce scarring. "Fast-acting" refers to a botulinum toxin that produces effects in the patient more rapidly than those produced by, for example, a botulinum neurotoxin type A. The "fast-acting" botulinum toxin, for example, type E.
Patent AU-2018250673-A1 (AU)
Title: Artificial tree assembly
Inventor: SANTA EDWIN
IPC: A01N3/00
Filed: 2018-04-12
Abstract: An improved artificial tree of the present invention is directed to a decorative artificial tree assembly which may be dimensioned and configured to fit on any supporting surface including, but not limited to, an interior floor, outside grounds, etc. The artificial tree may be disposed in an assembled or collapsed state. As such, the artificial tree may include a plurality tree segments and a cap member, vertically interconnected or stacked upon each other via a plurality of connectors. The artificial tree may be constructed from lightweight materials with decorative items attached to its outer surface.
Patent AU-2018256354-A1 (AU)
Title: Endovascular device for sensing and or stimulating tissue
Inventor: OXLEY THOMAS JAMES
IPC: A61F2/06
Filed: 2018-04-17
Abstract: Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.
Patent AU-2018283407-A1 (AU)
Title: Visibly transparent, near-infrared-absorbing and ultraviolet-absorbing photovoltaic devices
Inventor: BARR MILES
IPC: C07D333/60
Filed: 2018-06-15
Abstract: Visibly transparent photovoltaic devices are disclosed, such as those are transparent to visible light but absorb near-infrared light and/or ultraviolet light. The photovoltaic devices make use of transparent electrodes and near-infrared or ultraviolet absorbing visibly transparent photoactive compounds, optical materials, and/or buffer materials.
Patent AU-2018284937-A1 (AU)
Title: Uplink resource scheduling in multiple time instances
Inventor: ANDERSSON HAKAN
IPC: H04W72/12
Filed: 2018-12-24
Abstract: It is disclosed a network node (50; 60; 70), a communication device (80; 90; 100) and methods therein, for scheduling of uplink resources in multiple time instances and transmitting in accordance with the scheduled UL resources. By including (22) an indicator in an UL grant comprising an UL resource allocation, the indicator indicates that, for at least one UL time instance of the multiple time instances, at least one UL resource is excluded from, or added to, the UL resource allocation of the UL grant. Figure 1 INCLUDING AN INDICATOR IN AN UPLINK (UL) GRANT, THE INDICATOR INDICATING THAT AT 22 LEAST ONE UL RESOURCE IS EXCLUDED FROM, OR ADDED TO, RESOURCES OF THE * 24 TRANSMITTING SAID UL GRANT J RECEIVING AN UL TRANSMISSION IN 26 ACCORDANCE WITH THE TRANSMITTED UL Figure 2
Patent AU-2018297313-A1 (AU)
Title: Exosomes and methods of use thereof
Inventor: FREISHTAT ROBERT J
IPC: A61K35/35
Filed: 2018-07-06
Abstract: Exosomes, particularly adipocyte-derived exosomes, and methods of use thereof are provided.
Patent AU-2018299206-A1 (AU)
Title: Assemblies, systems and methods for programming medical devices
Inventor: SLUGGETT ANDREW
IPC: H04L9/32
Filed: 2018-07-12
Abstract: The present invention relates to medical device programming assemblies, systems and methods for programming a medical treatment parameter on a medical device, via a programming key. The programming key may be adapted to mate with the medical device which comprises a programmable, non-transitory, computer readable storage device. The storage device comprises a data connector which is configured to mate with a corresponding data connector on the medical device. The storage device may be affixed to a fastener coupling configured to mate with a corresponding coupling on the medical device when the data connector is brought into proximity with the corresponding data connector on the medical device. The programming key is configured to occupy a space formed within the medical device when the data connector and fastener coupling are mated with the corresponding data connector and fastener coupling of the medical device.
Patent AU-2018305877-A1 (AU)
Title: Method for the preparation of synthesis gas
Inventor: AASBERG-PETERSEN KIM
IPC: C01B3/38
Filed: 2018-07-20
Abstract: Method for the preparation of synthesis gas combining electrolysis of water, tubular steam reforming and autothermal reforming of a hydrocarbon feed stock.
Patent AU-2018308088-A1 (AU)
Title: Treating cancer by blocking the interaction of TIM-3 and its ligand
Inventor: SUN DONGXU
IPC: C07K16/28
Filed: 2018-07-24
Abstract: Provided herein are methods of activating immune response and/or treating cancer in a patient comprising administering to the patient a Gal3:TIM-3 inhibitor that interferes with the interaction between Gal3 and TIM-3, where said inhibitor is administered in an amount sufficient to activate immune response. Also provided are a humanized anti-Gal3 antibodies that can block the interaction between Gal3 and TIM3 and methods of using the anti-Gal3 antibody to treat cancer. Methods for determining if a patient's cancer is suitable for treatment with a Gal3:TIM-3 inhibitor and methods for selecting compounds that can block interaction between Gal3 and TIM-3, activating immune response and/or treating cancer are also provided.
Patent AU-2018308962-A1 (AU)
Title: Method and apparatus for forming a beaded can end
Inventor: TURNER STEPHEN B
IPC: B21D51/38
Filed: 2018-07-19
Abstract: A method and apparatus for forming a can end in a forming press (100) including positioning a sheet of material between an upper punch assembly (102) and 5 a fixed base assembly (104); cutting a can end blank (W) from the sheet of material; clamping a peripheral portion of the can end blank (W); moving the upper punch assembly (102) to clamp a central portion of the can end blank (W) between an upper panel punch (114) and a lower panel punch (118) to define a central panel section positioned below an annular inner bead die (116c) located adjacent to the lower panel 10 punch (118) on the fixed base assembly (104); and extending the upper punch assembly (102) to form an initial annular countersink radius (VI) next to the peripheral portion of the can end blank (W), with a substantially undeformed intermediate area extending between the initial annular countersink radius (VI) and the annular inner bead die (116c). An alternative embodiment of the method 15 described above and an apparatus for carrying out this method are also described. 11047217_1 (GHMatters) P110607.AU
Patent AU-2018336752-A1 (AU)
Title: Adaptive timing synchronization for reception for bursty and continuous signals
Inventor: ROHDE CHRISTIAN
IPC: H04L7/00
Filed: 2018-09-10
Abstract: There are provided examples of receivers, controller units (e.g., for the receivers) and related methods (e.g. for the receivers). One receiver is provided which comprises: an adjustable sample provider (604) configured to provide samples of an input signal using an adjustable sample timing; a feedback path (630) configured to provide a feedback signal to the adjustable sample provider (604) on the basis of a timing error (634), wherein the feedback path (630) comprises a loop filter (636) configured to provide sample timing information (638) to the adjustable sample provider (604); and a replacement value provider (640) configured to provide a replacement sample timing information (642) replacing the sample timing information (638) provided by the feedback path (630) when an input signal does not fulfil a predetermined requirement for a feedback-based sample timing adaptation, wherein the replacement value provider (640) is configured to provide the replacement sample timing information (642) considering a timing error information (634), or a quantity derived from the timing error information (634), over a longer time period when compared to a time period considered by the loop filter (636) for a provision of the sample timing information (638).
Patent AU-2018341370-A1 (AU)
Title: A method and apparatus for configuring resources and transmitting/receiving data in wireless cellular communication system
Inventor: PARK SUNGJIN
IPC: H04W72/12
Filed: 2018-10-01
Abstract: The present invention relates to a communication scheme and system for converging a 5
Patent AU-2018349732-A1 (AU)
Title: Permutation apparatus, permutation method, and program
Inventor: IKARASHI DAI
IPC: G09C1/00
Filed: 2018-10-02
Abstract: The present invention performs a replacement process at high speed. An element count determination unit (22) calculates the number of elements included in each allocation destination. A start position determination (23) calculates a start position that corresponds to each allocation destination. An allocation destination determination unit (24) calculates a row of values that represent allocation destinations in a buffer. A replacement generation unit (25) calculates a row of values that represent replacement destinations within each allocation destination. An initial position setting unit (31) sets the start position of a value indicating the position being processed that corresponds to each allocation destination. A rearrangement unit (32) sets the elements of a vector to each allocation destination of the buffer. A replacement execution unit (33) executes a discretionary reverse replacement algorithm for each allocation destination and thereby generates an output vector.
Patent AU-2018363783-A1 (AU)
Title: Maturation of mucosal defense and gut/lung function in the preterm infant
Inventor: NORKILD PETER
IPC: A61P11/00
Filed: 2018-11-09
Abstract: The present invention relates to methods for maturing the mucosal defense and rebalancing the immune system preventing a cytokine storm; treatment or prevention of neonatal sepsis, necrotizing enterocolitis, acute and prolonged diarrhea, short bowel syndrome, respiratory illness, respiratory infection, respiratory failure, impaired neurodevelopment and extra uterine growth restriction, the method comprising oral and/or intrapulmonary and/or subcutaneous administration of at least one antimicrobial peptide selected from the group consisting of α-defensins, β-defensins, cathelicidins, lactoferrins/lactoferricins and lysozymes and/or GLP-2 or GLP-2 analogs in a preterm infant or a mother about to give birth to a preterm infant.
Patent AU-2018364708-A1 (AU)
Title: Sting modulator compounds, and methods of making and using
Inventor: VYSKOCIL STEPAN
IPC: C07H21/02
Filed: 2018-11-09
Abstract: The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases. The present disclosure relates to a compound represented by the Formula (I): wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
Patent AU-2018425573-A1 (AU)
Title: Permanent-magnet synchronous motor and ventilation blower
Inventor: HOTTA KAZUHIKO
IPC: H02K19/10
Filed: 2018-05-30
Abstract: A permanent-magnet synchronous motor (100) is provided with: a main inverter circuit (3) that converts direct-current power to three-phase alternating-current power by switching a plurality of transistors (31–36); a motor body (20) that comprises a stator (21) and a rotor and is driven by the three-phase alternating-current power; a current detection unit (5) that determines an excitation current value and a torque current value on the basis of the value of two-phase motor current flowing through the stator (21) and an estimated value for the magnetic pole position of the rotor; a magnetic pole position detector (9) that determines the estimated value on the basis of the excitation current value, the torque current value, and impressed voltage information and outputs the estimated value to the current detection unit (5); a voltage computation unit (8) that determines the impressed voltage information by computation using the excitation current value, the torque current value, and an angular velocity determined on the basis of the estimated value so that the torque current value approaches a torque current command value; and an inverter control unit that controls the main inverter circuit (3) on the basis of the impressed voltage information and the estimated value.
Patent WO-2019218026-A1 (WO)
Title: A method and system for executing multi-dimensional data queries
Inventor: LYNCH MARYANNE
IPC: G06F8/35
Filed: 2019-05-17
Abstract: A software object model for use in programming or operating system environment, the object model including: • A multi -dimensional coordinate system, where the coordinates may be object instances rather than numeric axis values. • A method for constructing and handling hierarchical name spaces that allows for advanced key generation functions which can be matched with the processor bus width for improved computing efficiency, with the object model's key storage allowing for lookups to be done via number rather than text. • A multidimensional data rendering system where dimensions are superimposed on axes for viewing, making it easier to create multidimensional audio/visual representations of abstract structures.
Patent AU-2019200027-A1 (AU)
Title: Refractory cooking devices
Inventor: CASE TIMOTHY M
IPC: F24C3/00
Filed: 2019-01-03
Abstract: A cooking device may include a refractory oven and a housing. The refractory oven may define a cooking chamber that may be configured to receive thermal energy from an external heat source. The refractory oven may further define an opening 5 configured to allow foodstuffs to be introduced into the cooking chamber. The refractory oven may be further configured to substantially surround the foodstuffs while the foodstuffs are positioned inside the cooking chamber. The housing may at least partially surround the refractory oven. The housing and the refractory oven may define a heated volume between an external surface of the refractory oven and an internal surface of the 10 housing. The heated volume may be configured to receive thermal energy from the external heat source and to reduce transfer of thermal energy from the cooking chamber through refractory oven.
Patent AU-2019200703-A1 (AU)
Title: Waveform shapes for treating neurological disorders optimized for energy efficiency
Inventor: GRILL WARREN M
IPC: A61N1/36
Filed: 2019-02-01
Abstract: Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency. Waveform Shape 1/frequencyFi.A Amplitude Current 0 Pulse width Waveform Shape A L1/frequency Fig 1B Stimulation Energy (E Power 0 Pulse width t Rising Ramp Square (Rectangular) A time B time Sinusoid IstimFig. 2 stim C time Decreasing Exponential Rising Exponential Dstim D time Etime
Patent AU-2019203619-A1 (AU)
Title: Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
Inventor: SMITH JAMES JEFFERSON
IPC: C12N9/22
Filed: 2019-05-23
Abstract: Abstract: Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition sequence half-sites arejoined into a single polypeptide to form a functional heterodimer with a non-palindromic recognition sequence. The invention also relates to methods of producing such meganucleases, and methods of producing recombinant nucleic acids and organisms using such meganucleases.
Patent AU-2019217528-A1 (AU)
Title: Apparatus and methods for reducing generator frequency variation
Inventor: OLIVO TONY
IPC: H02J3/38
Filed: 2019-02-06
Abstract: A system includes a generator configured to be electrically coupled to a grid, an engine configured to drive the generator, and a solid state generator coupled between the grid and an energy storage device. The system further includes a bias controller configured to detect a frequency of the grid and to responsively provide a bias signal to a speed controller of the engine. The bias controller may include a frequency bias controller configured to generate a frequency bias load sharing signal responsive to the detected frequency of the grid and a load sharing controller that receives the frequency bias load sharing signal and that generates the bias signal responsive to the load sharing signal.