baber/WOPTO huggingface dataset:
Patent EP-3024492-A2 (EP)
Inventor: CAPLAN SHARI L
IPC: A61K47/48
Filed: 2014-07-21
Abstract: The invention provides a bioconjugates comprising a synthetic polypeptide of Formula I': I' or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein and a half-life extending moiety wherein the peptide and the half-life extending moiety are covalently linked or fuse, optionally via a linker. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the bioconjugates of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent EP-2967386-A2 (EP)
Inventor: GU XIANG IAN
IPC: A61B18/18
Filed: 2014-03-17
Abstract: A method and apparatus for measuring an impedance of a tissue region inside a body of a patient. A first guidewire is advanced into a tissue region of a body of a patient, wherein the first guidewire comprises one or more electrodes electrically coupled to the tissue region. A second guidewire is advanced into the body, wherein the second guidewire comprises one or more electrodes electrically coupled to the tissue region of the body of the patient and spaced from the first guidewire. An error correction electrode is electrically coupled to the body. A voltage is applied across the first and the second guidewires. The impedance of the tissue region between the first and the second guidewires is measured while using an electrical pathway created by the error correction electrode.
Patent EP-2981587-A2 (EP)
Inventor: CHEW ANDREW
IPC: C09K8/50
Filed: 2014-04-02
Abstract: Methods for treating a wellbore and compositions used for same are provided that include emplacing a polymer-forming composition in the wellbore, and initiating polymerization of the polymer-forming composition to form a polymerized material in the selected region of the wellbore. In some aspects, polymeric compositions provided may also be useful for isolating pressure differentials downhole.
Patent EP-2948375-A2 (EP)
Inventor: ENDRES STEVEN P
IPC: B64F1/06
Filed: 2014-01-22
Abstract: Systems and methods for ground-based aircraft thrust systems are provided. In particular, some embodiments use an electromechanical thrust assembly to accelerate aircraft using ground-based energy for takeoff. The assembly can include one or more sleds, one or more maglev tracks, and/or one or more linear motors. Airplanes are loaded onto a sled (e.g., a saddle-shaped sled) that supports and balances the airplane instead of the landing gear aboard the aircraft. The sled levitates above the ground using high-density permanent magnet arrays. Magnetic levitation forces are varied along the assembly to account for lift provided by airflow over the wings. An aircraft thrust system includes a magnetically levitated saddle-shaped sled with airbags that support an aircraft during takeoff acceleration coupled with a linear motor that spans the length of the distance needed for takeoff.
Patent EP-3063251-A2 (EP)
Inventor: BALASTRE MARC
IPC: C09D153/00
Filed: 2014-10-30
Abstract: Soil/seed hydrophilization polymers comprising: monomer A b  comprising at least one betaine group or at least one cationic group; and optionally, monomer B a  comprising at least one non-ionic group or at least one anionic group, wherein the polymer is water-soluble or water-dispersible; and provided that if the monomer A b  comprises a cationic group, the monomer Ba must be present and comprise an anionic group. Also disclosed are methods for treating soil comprising contacting the hydrophilization polymer with the soil, with improvements including increase in hydrophilicity of the soil, increase in root characteristics, increase in germination rates, as compared to soil without the hydrophilization polymer.
Patent EP-3060924-A2 (EP)
Inventor: BARNEA EYTAN R
IPC: C07K7/06
Filed: 2014-10-22
Abstract: Cells transfected with DNA sequences encoding for a PreImplantation Factor (PIF) or a PIF and one or more fusion tag(s) are disclosed. Also disclosed are DNA sequences encoding for synthetic PIFs, a PIF fusion peptide made of a PIF and one or more fusion tags, methods of treatment using the transfected cells that express a PIF, an R-I-K-P peptide, compositions containing the R-I-K-P peptide, and methods of identifying a compound that binds to an active site of an WX1WX2X3X4REWFX5X6X7W receptor, wherein each X can be any amino acid.
Patent EP-2974835-A2 (EP)
Title: Längsschneidsystem für bahnförmige materialien und verfahren zum betrieb eines längsschneidsystems
Inventor: BÄUMER JOSEF
IPC: B26D7/26
Filed: 2015-07-17
Abstract: Die Erfindung betrifft ein Längsschneidsystem 10 für bahnförmige Materialien 11 mit wenigstens einem oder mehreren Messern 25 zum Zerschneiden eines bahnförmigen Materials 11 in Längsrichtung. Jedes Messer 25 ist dabei einem Messerhalter 24 zugeordnet. Das Längsschneidsystem 10 zeichnet sich dadurch aus, dass eine gemeinsame Haltevorrichtung 23 zur Aufnahme und lösbaren Befestigung mehrerer Messerhalter 24 vorgesehen ist, so dass alle in die Haltevorrichtung 23 eingebrachten Messer 25 gemeinsam verstellbar sind.
Patent EP-3108216-A2 (EP)
Title: Verfahren und vorrichtung zum erzeugen von multi- oder hyperspektralem licht, zur hyperspektralen bildgebung und/oder zur distanz- und/oder 2-d oder 3-d profilmessung eines objekts mittels spektrometrie
Inventor: KÖRNER KLAUS
IPC: G01J3/10
Filed: 2015-02-17
Abstract: Die vorliegende Erfindung betrifft Verfahren und Vorrichtungen zum Erzeugen von multispektralem Beleuchtungslicht mit adressierbarem Spektrum, zur adaptiven multispektralen Bildgebung sowie zur Erfassung von strukturellen und/oder topographischen Informationen eines Objekts oder der Distanz zu einem Objekt. Die Beleuchtungsvorrichtung umfasst eine multispektrale Lichtquelle und eine Modulationseinrichtung zur zeitlichen Modulation der einzelnen Spektralkomponenten der multispektralen Lichtquelle mit jeweils voneinander unterschiedlichen Modulationsfrequenzen, Modulationsfrequenzbereichen und/oder Modulationssequenzen. Die multispektrale Lichtquelle umfasst (i) zumindest eine Lichtquelle (10) mit einem kontinuierlichen, quasi-kontinuierlichen oder Frequenzkamm-Spektrum und wellenlängendispersiven Mitteln (12) oder (ii) ein Ensemble oder Array von monochromatischen oder quasi- monochromatischen Lichtquellen mit voneinander jeweils verschiedenen Emissions-Wellenlängen oder Emissions-Wellenlängenbändern. Die Modulationseinrichtung umfasst (i) mindestens einen elektrisch steuerbaren, räumlichen Lichtmodulator (14) oder (ii) mehrere, der einzelnen monochromatischen oder quasi- monochromatischen Lichtquellen zugeordnete elektronische Ansteuermodule. Die Beleuchtungsvorrichtung umfasst ferner optische Mittel (18) zum Zusammensetzen der einzelnen modulierten Spektralkomponenten, um das multispektrale Beleuchtungslicht (24) mit adressierbarem Spektrum zu bilden.
Patent EP-3123483-A2 (EP)
Inventor: VAN HATTUM EDGAR JOHANNES
IPC: D01F6/62
Filed: 2015-03-26
Abstract: L'invention concerne une fibre en plastique présentant une conductivité électrique. La matière de la fibre est formée à partir d'une matière première de base en PET. Des éléments sont insérés dans cette matière première de base. Ces éléments présentent un ordre atomique et se chevauchent au moins dans certaines zones au niveau de leur nuage électronique.
Patent EP-3155252-A2 (EP)
Inventor: GONIDEC PATRICK
IPC: F02K1/12
Filed: 2015-06-05
Abstract: The invention relates to a thrust reverser (18) for a nacelle (10) of an aircraft turbofan including at least one movable thrust reverser cover (20), a means for locking the cover (20), a variable-exhaust output nozzle (22) which is arranged forming a downstream extension of said cover (20) and which is movable, and at least one actuator (24) which includes an actuator rod (28) suitable for moving the variable nozzle (22) and the movable cover (20), characterised in that the reverser (18) is provided with a resilient coupler (30) comprising a body (32) which is rigidly connected to the thrust reverser cover (20), resilient return means (48) and abutments which are supported by the body (32) of the coupler (30) and which engage with the actuating rod (28) of the actuator (24) such as to resiliently return the nozzle (22) into the neutral position thereof, said return means (48) being calibrated such that, when the cover (20) is unlocked, the return means (48) oppose the relative movement of the actuating rod (28) relative to the cover (20), such as to enable the movement of the assembly consisting of the cover (20) and the nozzle (22), and when the cover (20) is locked, the actuator (24) drives the actuating rod (28) against the return means (48), such as to enable the movement of the nozzle (22).
Patent EP-3122350-A2 (EP)
Inventor: SHAMLOO MEHRDAD
IPC: A61K31/24
Filed: 2015-02-18
Abstract: La présente invention concerne un composé de promédicament d'agoniste β 1 -ADR qui est hydrolysable in vivo pour libérer un composé d'agoniste β 1 -ADR, ledit composé promédicament contenant un groupe qui confère une meilleure lipophilie et biodisponibilité du système nerveux central pour le composé promédicament par rapport au composé d'agoniste β 1- ADR.
Patent EP-3183336-A2 (EP)
Title: Réinitialisation de cellules souches pluripotentes
Inventor: SMITH AUSTIN
IPC: C12N5/0735
Filed: 2015-08-21
Abstract: Cette invention concerne des procédés et des matériels permettant de réinitialiser ou de maintenir une cellule souche humaine à l'état "naïf" ou "zéro", basés sur l'utilisation de milieux contenant des combinaisons d'inhibiteurs. Un exemple de milieu de culture naïf comprend un inhibiteur de PKC et un inhibiteur de MEK. L'invention concerne également des procédés permettant d'obtenir ou de propager ces cellules, des cellules obtenues à l'aide de ces procédés, et de nouveaux milieux de culture, qui peuvent être utilisés dans ces procédés.
Patent EP-3212496-A2 (EP)
Inventor: CERMELLI CHRISTIAN
IPC: B63B35/44
Filed: 2015-10-27
Abstract: L'invention concerne un connecteur flottant d'un dispositif d'énergie en mer et un procédé permettant de connecter le connecteur flottant. Le connecteur flottant comprend une bouée ayant un flotteur de type espar long, la bouée assurant la flottaison du connecteur flottant. Le connecteur flottant comprend en outre au moins deux câbles destinés à être connectés au dispositif d'énergie en mer. Le connecteur flottant comprend également une boîte de jonction pour le couplage au dispositif d'énergie en mer et pour la fourniture d'une connexion électrique des deux câbles ou plus à un appareillage de commutation du dispositif d'énergie en mer. Lorsque la boîte de jonction est couplée au dispositif d'énergie en mer, un circuit électrique doté des deux câbles ou plus est achevé par le dispositif d'énergie en mer par l'intermédiaire de l'appareillage de commutation.
Patent EP-3150142-A2 (EP)
Inventor: HARRIS JASON L
IPC: A61B17/00
Filed: 2016-09-30
Abstract: A staple cartridge assembly comprising an implantable adjunct or layer assembly is disclosed. The implantable adjunct comprises a plurality of layers, wherein at least one of the layers has been melted to bond with one or more of the other layers of the implantable adjunct.
Patent EP-3268725-A2 (EP)
Inventor: KRIEG GUNTHER
IPC: B29B17/02
Filed: 2016-02-05
Abstract: L'invention concerne un procédé d'identification de matières plastiques et/ou de leurs additifs, au moins une partie de la matière plastique étant exposée à une lumière d'au moins une longueur d'onde, au moins une partie de la lumière renvoyée par la matière plastique étant détectée et analysée, et la matière plastique et/ou ses additifs étant identifiés sur la base du résultat de l'analyse. Le procédé est caractérisé en ce qu'une constante de temps de déclin de fluorescence de la fluorescence intrinsèque de la matière plastique et éventuellement de son (ses) additif(s) est déterminée à partir de la lumière détectée, et la matière plastique et/ou son (ses) additif(s) sont identifiés sur la base de la constante de temps de déclin de fluorescence déterminée.
Patent EP-3303379-A2 (EP)
Inventor: GURNEY AUSTIN
IPC: C07K14/47
Filed: 2016-05-27
Abstract: L'invention concerne des agents qui se lient spécifiquement à TIGIT. Les agents de liaison à TIGIT peuvent comprendre des polypeptides, des anticorps et/ou des agents bispécifiques. L'invention concerne également des procédés d'utilisation de ces agents pour améliorer la réponse immunitaire et/ou pour le traitement de maladies telles que le cancer.
Patent EP-3192415-A2 (EP)
Inventor: NERNBERGER KROY EVERETT
IPC: B02C18/12
Filed: 2014-03-14
Abstract: A container (104) for a food preparation appliance has a closed end, an open end and a tubular sidewall (108) extending from the closed end to the open end. The container (104) is configured to accommodate a blade member (502) within the interior space (114) of the container (104). The sidewall (108) has a rib (202,204,206) projecting inward of the interior space (114) of the container (104) and extending lengthwise along at least a portion of the sidewall (108) intermediate the open end and closed end. The rib (202,204,206) has, in the direction of rotation of the blade member (502), a peak (212,217,218) defined as the shortest transverse dimension measured from the center (c) of the container (104) to the sidewall (108) at a respective height along the portion of the sidewall (108) having the rib (202,204,206), with the rib being asymmetric in transverse cross-section.
Patent EP-3475514-A2 (EP)
Title: Lamelle pour volets roulants et volet roulant obtenu avec celle-ci
Inventor: CIULLI CHIARA
IPC: E06B9/15
Filed: 2017-06-28
Abstract: La présente invention concerne une lamelle pour volets roulants comprenant une feuille allongée plane (100) présentant une direction longitudinale (90) et une direction transversale (40), la feuille (100) présentant un premier bord longitudinal et un second bord longitudinal, le premier bord longitudinal formant une première spirale (50) et le second bord longitudinal formant une seconde spirale (60), la première spirale (50) et la seconde spirale (60) ayant un même sens de rotation (70, 80), les première et seconde spirales ayant un premier et un second axe longitudinal (20, 30) parallèles à la direction longitudinale (90), la feuille (100) et les premier et second axes longitudinaux (20, 30) se trouvant sur un même plan.
Patent EP-3510348-A2 (EP)
Inventor: RAHO GUGLIELMO
IPC: G01B5/004
Filed: 2017-09-01
Abstract: A recess or pocket is formed in at least one leg of a moving bridge assembly of a coordinate measuring machine, and in a particular embodiment in a primary leg of a moving bridge assembly, to permit a quill to move farther in the X direction to an end of a planar base surface of the coordinate measuring machine adjacent the leg without interfering with the leg. The recess formed in the leg of the moving bridge assembly permits coordinate measurements of a part whose width covers the full area of the planar surface of the base, without necessarily adding significant cost or increasing the footprint of the measurement system.
Patent EP-3422388-A2 (EP)
Inventor: TAKAHASHI HIDENORI
IPC: H01J49/00
Filed: 2018-06-26
Abstract: Lipid-derived ions captured within an ion trap are irradiated with hydrogen radicals to induce the reaction of hydrogen extraction (S1, S2). A precursor-ion isolation process is subsequently performed (S3), and the precursor ion is dissociated by low-energy collision-induced dissociation (S4). The thereby generated product ions are subjected to mass spectrometry to create a product-ion spectrum (S5, S6). Since the dissociation achieved by such a procedure does not cause hydrogen rearrangement, a peak pair having a mass difference of +12 Da characteristic of the unsaturated bond site certainly appears on the product-ion spectrum. By searching for this peak pair, the unsaturated bond site can be located (S7, S8). By such a method, a lipid-structure analysis including the determination of the position of the unsaturated bond site in a lipid can be performed in a stable and accurate manner without requiring derivatization or other cumbersome pretreatments.
Patent EP-3522017-A2 (EP)
Inventor: NUGENT CHARLES PATRICK
IPC: G06F9/54
Filed: 2018-12-06
Abstract: A streaming platform reader includes: a plurality of reader threads configured to retrieve messages from a plurality of partitions of a streaming platform, wherein each message in the plurality of partitions is associated with a unique identifier; a plurality of queues coupled to the plurality of reader threads configured to store messages or an end of partition signal from the reader threads, wherein each queue includes a first position that stores the earliest message stored by a queue; a writer thread controlled by gate control logic that: compares the identifiers of all of the messages in the first positions of the queues of the plurality of queues, and forwards, to a memory, the message associated with the earliest identifier; and wherein the gate control logic blocks the writer thread unless each of the queues contains a message or an end of partition signal.
Patent EP-3711251-A2 (EP)
Title: Ue processing time for uci multiplexing
Inventor: SORIAGA JOSEPH BINAMIRA
IPC: H04L5/00
Filed: 2018-11-16
Abstract: Various additional and alternative aspects are described herein. In some aspects, the present disclosure provides techniques for determining timing conditions for uplink control information (UCI) processing by a user equipment (UE).
Patent EP-3576193-A2 (EP)
Inventor: HAN GI BEOM
IPC: C01G53/00
Filed: 2018-09-07
Abstract: The present invention provides a positive electrode active material comprising a lithium-rich lithium manganese-based oxide, 
wherein the lithium-rich lithium manganese-based oxide is represented by the following chemical formula (1), 
 
        Li 1+a Ni x Co y Mn z M v O 2-b A b      (1) 
 
wherein, 0<a≤0.2, 0<x≤0.4, 0<y≤0.4, 0.5<z≤0.9, 0≤v≤0.2, a+x+y+z+v=1, and 0≤b≤0.5; 
M is one or more elements selected from the group consisting of Al, Zr, Zn, Ti, Mg, Ga, In, Ru, Nb, and Sn; and 
A is one or more elements selected from the group consisting of P, N, F, S and Cl; 
wherein (i) lithium tungsten (W) compound, or the (i) lithium tungsten (W) compound and (ii) tungsten (W) compound are contained on a lithium-rich lithium manganese-based oxide, wherein the (i) lithium tungsten (W) compound including a composite of the (ii) tungsten (W) compound and a lithium, and 
wherein the (i) lithium tungsten (W) compound, or the (i) lithium tungsten (W) compound and the (ii) tungsten (W) compound are contained in an amount of 0.1% to 7% by weight based on the total weight of the positive electrode active material, and a method for producing the same.
Patent EP-3720474-A2 (EP)
Title: Products and methods for assessing and increasing klotho protein levels
Inventor: TARSIO JOSEPH F
IPC: A61K38/47
Filed: 2018-12-06
Abstract: Disclosed are products and methods for monitoring Klotho protein levels and for stabilizing Klotho protein in a mammalian blood sample, especially at room temperature or without freezing, for a period of time. Methods of detecting and quantifying Klotho protein levels, particularly endogenous and/or exogenous soluble alpha Klotho protein levels, methods of diagnosing Klotho protein deficiency, and methods of increasing Klotho protein levels or production, particularly endogenous and/or exogenous soluble alpha Klotho protein level(s), expression, or production, in a mammalian subject, and products useful in performing the same, including diagnostic kits and compositions for treating Klotho protein deficiency, are disclosed. Compositions are configured or formulated to augment natural soluble alpha Klotho protein production, attenuate Klotho protein damage or degradation, and/or supplement Klotho protein levels with exogenous, recombinant protein. Treatment methods and uses include administration of the compositions to human or non-human mammalian subjects.
Patent EP-3522200-A2 (EP)
Inventor: HONKALA JORMA
IPC: G01T1/40
Filed: 2019-01-31
Abstract: A photomultiplier tube for use in an imaging plate scanner. In one embodiment, the photomultiplier tube includes a housing having a window; a focusing electrode located in the housing; an electron multiplier dynode located in the housing; an anode; a cathode and a memory storing parameters. Another embodiment provides An imaging plate scanner including a photomultiplier tube having a window, an anode, and a cathode; a light source positioned to radiate light on the anode or cathode; and an electronic processor communicatively coupled to the light source and configured to generate a supply voltage value for the photomultiplier tube, activate the light source and determine an output current of the anode or of the cathode, and generate an error message if the output current deviates from an expected current range. A power supply is electrically connected to the electronic processor and configured to generate the supply voltage.
Patent EP-3543981-A2 (EP)
Inventor: NOBLE ECHEVERRIA JON
IPC: G08B15/02
Filed: 2016-11-04
Abstract: A smoke generator (100) for anti-burglar purposes comprising canister holding means (805, 815) for holding a canister (810) for chemicals to be used to generate smoke wherein the smoke generator further comprises a smoke deflector (103) arranged below the position of the canister for even distribution of generated smoke, and wherein the smoke deflector (103) have a smoke deflector cavity of sector shape. The smoke generator is provided with a cartridge for the canister to ease replacement of used or expired canister. The smoke deflector is provided with a residual collector (120) to prevent residuals and debris from littering the room where the smoke generator is used.
Patent EP-3636104-A2 (EP)
Title: Kopplungsvorrichtung für auszugsführung
Inventor: MEIER BRUNO
IPC: A47B88/427
Filed: 2019-09-24
Abstract: Die Erfindung betrifft eine Vorrichtung zur Kopplung eines Schubkastens an einer Laufschiene einer Auszugsführung enthaltend ein Befestigungsmittel zum Befestigen der Vorrichtung an dem Schubkasten, ein Rastelement zum rastenden Verbinden der Vorrichtung mit der Laufschiene, einem Betätigungselement zum Verbringen des Rastelementes in eine Kopplungsstellung, in der das Rastelement rastend mit der Laufschiene verbunden ist, und in eine Nichtkopplungsstellung, in der das Rastelement nicht mit der Laufschiene verbunden ist, wobei das Befestigungsmittel, das Rastelement und das Betätigungselement einstückig miteinander verbunden sind unter Bildung eines einzigen Kopplungsteils, das Kopplungsteil zwei parallel zueinander verlaufende Längsstreben aufweist, an denen jeweils außenseitig das Rastelement angeformt ist, das die Längsstreben mit einem ersten Ende an einem das Befestigungsmittel aufweisenden Basiselement des Kopplungsteils angeformt sind und dass das Betätigungselement auf einer zueinander gekehrten Seite der beiden Längsstreben von demselben abragt.