Patent SG-11201909997V-A (SG)
Title: Biodegradable bone glue
Inventor: XUE TENG
IPC: C08G63/664
Filed: 2018-04-27
Abstract: ON N -1 00 1-1 O (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 01 November 2018 (01.11.2018) WIPO I PCT omit VIII °nolo Hi 01° mo mo Homo oimIE (10) International Publication Number WO 2018/197706 Al (51) International Patent Classification: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, CO8G 63/664 (2006.01) CO8G 81/02 (2006.01) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, A61L 24/04 (2006.01) KM, ML, MR, NE, SN, TD, TG). (21) International Application Number: (22) International Filing Date: PCT/EP2018/060965 Declarations under Rule 4.17: as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.1 7 (iii)) 27 April 2018 (27.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/491,665 28 April 2017 (28.04.2017) US (71) Applicant: EVONIK ROHM GMBH [DE/DE]; Kirschenallee, 64293 Darmstadt (DE). (72) Inventors: XUE, Teng; 57-1-802, Xi Nan District, Nankai University, TIANJIN, 300071 (CN). LUPPI, Gianlui- gi; 801 Montclair Rd., Apt. 3201, Birmingham, Alaba- ma 35213 (US). SAVIETTO, Natalia Ruggeri; 115 Sun- rise Dr., Whippany, New Jersey 07981 (US). BOWMAN III, Howard K.; 5500 Surrey Lane, Birmingham, Al- abama 35242 (US). SPENCER, Paul Joseph; Mozart- strasse 13B, 61440 Oberursel (DE). KARAU, Andreas; Am Langen Steg 32A, 63571 Gelnhausen (DE). ZHANG, Jian-Feng; 1625 Canterbury Circle, Vestavia, Alabama 35243 (US). LIZIO, Rosario; Beethovenstrasse 15, 64807 Dieburg (DE). JONES, Marshall Scott; 4571 Deer Creek Trail, Bessemer, Alabama 35022 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Published: — with international search report (Art. 2 1 (3)) (54) Title: BIODEGRADABLE BONE GLUE (57) : The present invention is directed to bioresorbable polymers to be used as bone and tissue adhesives. The present invention is also directed to the synthesis of bioresorbable polymeric molecules bearing adhesive moieties and the use of such compounds in methods to glue and stabilize fractured bones and damaged tissues. The present invention is also directed to the use of such compounds as adhesive sealants for applications in wound care. The present invention is also directed to the use of such compounds as biodegradable ink for applications in tissue engineering and 3D printing. The present invention also relates to the use of such compounds as drug delivery platforms.