baber/WOPTO huggingface dataset:
Patent AT-E313803-T1 (AT)
Inventor: PATCHEV VLADIMIR
IPC: G01N33/50
Filed: 2001-11-07
Granted: 2006-01-15
Abstract: A method of an in vitro screening for a ligand using two assay systems i.e. in a first cellular or tissue assay system, selecting the ligand with transcriptional ER-mediated activity measured by an ER-driven reporter gene, whereby in the first assay system the ligand activates the potency with an EC50(ER) (half-maximally effective ligand concentration) lower than to 10 nmol/l, and, in a second enzymatic assay system, selecting the physical-chemical interaction (recruitment) of SRC-1, wherein the ligand activates the ER and induces interaction with the co - present SRC-1 with an EC50(ER+SRC) higher than to 100 nmol/l. The ligands found by the inventive screening can be used for the treatment and prevention of neuro - degeneration in the cerebral cortex and are thus useful for treatment and prevention of age-related cognitive disorders, affective disorders, Alzheimer's diseases and cerebral ischemia / stroke.
Patent AT-E445847-T1 (AT)
Inventor: SAHA MURARI
IPC: G01R31/08
Filed: 2001-12-14
Granted: 2009-10-15
Abstract: The present invention relates to a method for calculating the distance to fault in a section of a power transmission network, which section is arranged with line terminals at both ends, each terminal including impedance relays (AA, BB), including the steps of, at the occurence of a fault; measuring the apparent impedances by each relay, measuring the relaying currents, determining the type of fault, checking whether the fault involves a fault resistance or not, and, if so, solving a quadratic equation for complex numbers, resolving the quadratic equation for the real and imaginary components, obtaining two quadratic equations for a fault distance in which the coefficients are real numbers, combining the two equations and obtaining a distance to fault, or, if not so, solving a quadratic equation for real numbers, obtaining two solutions for the distance to fault d<SUB>1</SUB>, d<SUB>2 </SUB>and comparing the solutions as 0<(D<SUB>1 </SUB>or d<SUB>2</SUB>)<1 pu, where pu is the length of transmission lines between the line terminals.
Patent AT-E273144-T1 (AT)
Inventor: MENNESSON DOMINIQUE MARIE CHRI
IPC: B60G13/00
Filed: 2001-11-23
Granted: 2004-08-15
Abstract: The end of the damper rod (2) or cylinder (1) is connected to the vehicle bodywork (C) by a flexible articulation using an elastomer filtering element (14). The filtering element comprises an annular block which concentrically surrounds the rod and is fixed to the bodywork by a rigid support (15) and connected to the rod end by a bell-shaped component (23) whose side wall (24) surrounds the rod. A rigid circular plate (25) delimits with the collar shaped wall (27) of the bell-shaped part a housing for the annular block.
Patent AT-E301902-T1 (AT)
Inventor: KLOTSCHE RALF
IPC: H04L12/54
Filed: 2001-08-29
Granted: 2005-08-15
Abstract: The router has a buffer memory (3) which intermediately stores pointers for information packets into different buffer memory areas (4,5). An additional memory area (6) is provided to store the selected pointers. The selected pointers are read from the additional memory area before reading the pointers in the other memory areas.
Patent AT-E292646-T1 (AT)
Inventor: CHEN BEINING
IPC: C08G85/00
Filed: 2001-01-25
Granted: 2005-04-15
Abstract: A computer aided rational molecular design method that includes establishing a virtual library of functional monomers each having a portion that is capable of polymerizing and a functional group that is capable of interacting with a template molecule with the aid of a computer, designing a molecular model of a biological template molecule by a computer facilitated molecular mechanical method and screening said virtual library of functional monomers and selecting those monomers which have the highest binding score to the template molecule by their functional group.
Patent AT-E286881-T1 (AT)
Inventor: SAKA YASUHIRO
IPC: C07D205/04
Filed: 2001-02-02
Granted: 2005-01-15
Abstract: The invention provides a process for producing optically active azetidine-2-carboxylic acid with good efficiency, expedience, and commercial advantage, which comprises cyclizing an optically active 4-amino-2-halogenobutyric acid in an optical yield of as high as 90% or more. It is a process for producing optically active azetidine-2-carboxylic acid of the general formula (2), in which * denotes an asymmetric carbon atom, which comprises cyclizing an optically active 4-amino-2-halogenobutyric acid of the general formula (1),in which X represents a halogen atom and * denotes an asymmetric carbon atom, in the presence of an oxide of an alkaline earth metal, a hydroxide of an alkaline earth metal excepting barium, or an organic amine. <CHEM>
Patent AT-E383117-T1 (AT)
Inventor: CRAGG ANDREW
IPC: A61N1/05
Filed: 2001-02-14
Granted: 2008-01-15
Abstract: Methods for correcting a deformity in the spine by forming a trans-sacral axial instrumentation/fusion axial bore through vertebral bodies in general alignment with a visualized, anterior axial instrumentation/fusion line in a minimally invasive, low trauma, manner and providing a therapy to the spine employing the axial bore. Curved or relatively straight anterior axial bores are formed from the anterior starting positions. The therapies performed through the axial bores include discoscopy, full and partial discectomy, vertebroplasty, balloon-assisted vertebroplasty, drug delivery, electrical stimulation and various forms of spinal disc cavity augmentation, spinal disc replacement, fusion of spinal motion segments and implantation of radioactive seeds. Axial spinal implants and bone growth materials can be placed into single or multiple parallel or diverging axial bores to fuse two or more vertebrae, or distract or shock absorb two or more vertebrae.
Patent AT-E360439-T1 (AT)
Inventor: VON KNEBEL DOEBERITZ MAGNUS
IPC: A61K48/00
Filed: 2001-02-07
Granted: 2007-05-15
Abstract: A pharmaceutical preparation, comprising a cell-cycle regulatory protein, and/or a nucleic acid encoding that protein, for immunization against carcinoma and its preliminary stages, is new. - ACTIVITY : Cytostatic. Peripheral blood lymphocytes were isolated from an HLA-A0201 positive sample by density centrifugation and T lymphocytes were separated from monocytes and B lymphocytes using antibodies coupled to magnetic beads (CD11, CD16, CD19, CD36 and CD56) (T cell isolation kit, Milteny, Germany). Peptides of p16 were identified using a software system (NIH bioinformation service) including the following peptides ValMetMetMetGlySerAlaArgVal, ValLeuHisArgAlaGlyAlaArgLeu, TheLeuThrArgProValHisAspAla, LeuLeuHisGlyAlaGluProAsnCys, SerMetGluProSerAlaAspMetLeu, MetMetGlySerAlaArgValAlaGluLeu, LeuLeuLeuHisGlyAlaGluProAsnCys, GlyValMetMetMetGlySerAlaArgVal. The isolated T cells were incubated with T2 cells and a mixture of the 9mer (a) or 10mer (b) peptides. The T cells were re-stimulated weekly over a six week period. In each case 10 7> T-cells were co-cultivated with 2x10 6> peptide-loaded T2 cells in 24 well plates. Reaction against the peptide-loaded T2 cells was determined weekly using an interferon (IFN)-lambda enzyme linked immunosorbent assay (ELISA). On day 28 reaction against mixture (a) was observed with the main reaction being against peptide ValMetMetMetGlySerAlaArgVal (1000 specific cells per million cells), and a weaker reaction against mixture (b) with peptide MetMetGlySerAlaArgValAlaGluLeu being the highest (600 specific cells per million cells). Thus it is clear that CD8 +> T-cells can be stimulated against p16. These activated T-cells were incubated with human leukocyte antigen (HLA) A0201+ Caski cervix carcinoma cells which over-express p16, and with colon carcinoma line SW480 which do not over-express p16. The Caski cells were lysed, whilst the controls were not. - MECHANISM OF ACTION : Vaccine; gene therapy.
Patent AT-E443307-T1 (AT)
Inventor: SHIEH SHIUH-AN
IPC: G01G19/12
Filed: 2001-04-04
Granted: 2009-10-15
Abstract: A passenger detection system is provided. The passenger detection system utilizes an oscillation circuit that causes an antenna electrode to emit an electric field that is disrupted by the electrical characteristics of an object placed on the seat. This disruption alters the current and phase of the signal in the antenna electrode. By comparing the current flowing in the antenna electrode and/or the difference between the phase of the signal in the antenna electrode and the oscillation circuit output signal with predetermined threshold values, it is possible to detect the presence of a passenger in a reliable and inexpensive manner. The determination is made with a two layer electrode arrangement, including smaller and larger electrodes. The two layers allow calculation of an amount of compression on the seat. The amount of compression is used to characterize the passenger.
Patent AT-E340609-T1 (AT)
Inventor: AMBROSEN HELEN
IPC: A61K8/00
Filed: 2001-04-27
Granted: 2006-10-15
Abstract: A cosmetic lotion comprising 16% to 76% by weight cocoa butter and having a solid rather than liquid form. Also a method of manufacturing a cosmetic lotion having an oil based component and a water based component characterised by selecting the oil based component to comprise cocoa butter so that the cocoa butter constitutes 16% to 76% by weight of the final form of the lotion; heating the cocoa butter to a temperature in the range 55° to 70° C.; cooling the cocoa butter to a temperature in the range 35° to 25° C. and at a temperature in that range adding the water based component.
Patent AT-E346380-T1 (AT)
Inventor: HATTA YOSHIHISA
IPC: H01L21/302
Filed: 2001-05-08
Granted: 2006-12-15
Abstract: The invention provides a semiconductor device and a method for forming patterns in which the manufacturing cost is reduced while the step coverage is improved. The ITO film 50 and the MoCr film 100 are dry-etched after having formed the ITO film 50 and the MoCr film 100.
Patent AT-E361613-T1 (AT)
Inventor: WITTIG KARL
IPC: H03H17/00
Filed: 2001-05-21
Granted: 2007-05-15
Abstract: An adaptive channel equalizer with adaptive coefficients for compensating for long delays multipaths and distortions. A training sequence is periodically sent over the channel and the adaptive coefficients of the equalizer are periodically updated from the equalization of the transmitted training sequence. The equalization of the training sequence is performed separately and in parallel to the equalization of the remaining transmitted data by the equalizer.
Patent AT-E298975-T1 (AT)
Inventor: REINCKE MARINUS
IPC: A01B51/02
Filed: 2001-06-28
Granted: 2005-07-15
Abstract: The invention relates to a device for maintaining grass fields, provided with a frame (1) movable along a ground surface, supporting on one or more support wheels (2), a gearbox with power take-offs (5), a steering handle (11), a drive motor (10), and with exchangeable working attachments which can be fixedly connected to the device and another support wheel (7) on one side adjacently of this working attachment which can be connected fixedly, pivotally or for active steering to the frame with a supporting arm (8) which is adjustable in position and lockable.
Patent AT-E304582-T1 (AT)
Inventor: BACHON THOMAS
IPC: C04B26/02
Filed: 2001-07-28
Granted: 2005-09-15
Abstract: An aqueous adhesive system consisting of two separate components, A and B. Component A is an aqueous dispersion of polymer containing at least one olefinically unsaturated double bond and Component B consists of a dispersion of a drying agent in an oil phase liquid. The adhesive produced by this system is useful for bonding material made of wood, cork, metal, plastic, stone and concrete.
Patent AT-E392597-T1 (AT)
Inventor: MALINDRETOS LARS
IPC: F41A9/18
Filed: 2001-08-16
Granted: 2008-05-15
Abstract: The invention relates to a device for feeding cartridges ( 15 ) from magazines to small arms, in particular to rifles with a cartridge feed device ( 3-7, 25-29 ), which transports the cartridges from a tubular magazine ( 11 ) to the barrel ( 1 ) by means of a device, in particular a rocker/spoon ( 3, 25-29 ). Said device comprises a breech, which receives the cartridges from the cartridge feed device, slides them into the barrel and closes the latter. The rocker/spoon of the cartridge feed device can be removed from the intermediate chamber between the tubular magazine and the lock ( 13 ) and an interchangeable cartridge magazine ( 16 ) can be inserted in the empty intermediate chamber ( 21 ). In a first embodiment, the rocker ( 3 ) can be displaced from a front position into a rear position. In a second embodiment, the rocker ( 3 ) can be pivoted from an upper, approximately horizontal position into a lower, approximately perpendicular position. In a third embodiment, the rocker ( 3 ) is surrounded by a box, which together with the rocker can be removed from the weapon, in a similar manner to the interchangeable magazine.
Patent AT-E324795-T1 (AT)
Inventor: LIN PETER YAU TAK
IPC: A23G3/00
Filed: 2001-09-25
Granted: 2006-06-15
Abstract: Described is an improved emulsifier system suitable for use in making dehydrated starch ingredients. Also disclosed are a process for making the dehydrated ingredients using the improved emulsifier systems, doughs made using the dehydrated ingredients and the process for making those doughs, and food products containing the dehydrated ingredients.
Patent AT-E322264-T1 (AT)
Inventor: OZAWA YOICHI
IPC: A61P35/00
Filed: 2001-10-31
Granted: 2006-04-15
Abstract: The present invention provides a medicinal composition having an excellent antitumor activity. That is, it provides a medicinal composition comprising a sulfonamide compound, a sulfonate compound or a salt of them, which is represented by the following formula: <CHEM> (wherein ring A represents an aromatic ring which may have a substituent group; ring B represents a 6-membered unsaturated hydrocarbon ring which may have a substituent group etc.; ring C represents a 5-membered hetero-ring containing one or two nitrogen atoms, and the ring C may have a substituent group; W represents a single bond or -CH=CH-; X represents -NH- etc.; and Y represents a carbon atom or a nitrogen atom; and Z represents -NH- etc.), particularly N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzenesulfonamide or a salt thereof, combined with at least one substance selected from (1) irinotecan hydrochloride trihydrate; (2) mitomycin C; (3) 5-fluorouracil; (4) cisplatin; (5) gemcitabinehydrochloride; (6) doxorubicin; (7) taxol; and (8) a salt of the above-mentioned (1) to (7). <IMAGE>
Patent AT-E321286-T1 (AT)
Inventor: DIETZSCH LEANDER
IPC: G02B21/00
Filed: 2001-10-02
Granted: 2006-04-15
Abstract: A reflector turret for an inverted microscope, having a cover which is water-tight at least at the top and substantially light-tight outside the microscope beam path, wherein a protective glass is fitted into the upper part of the cover in the light path so as to be tight against liquid, and the protective glass is removable and/or exchangeable.
Patent AT-E276533-T1 (AT)
Inventor: OWEN GEOFFREY DONALD
IPC: G02B26/10
Filed: 2001-11-29
Granted: 2004-10-15
Abstract: An optical deflector comprises an aspheric deflecting lens (1, 13) of positive optical power. The deflecting lens (1, 13) has a first relatively short focal length giving rise to a first focal point (3) and a second relatively long focal length giving rise to a second focal point (5). Thus, a divergent beam (7) of light substantially at one of the first and second focal points is focussed by the lens at the other of the first and second focal points. Means (19), such as an electric motor, is provided for rotating the lens about an axis substantially coincident with one of the first and second focal points.
Patent AT-E357872-T1 (AT)
Inventor: ZORZO BRUNO
IPC: A47L13/60
Filed: 2002-01-22
Granted: 2007-04-15
Abstract: This patent is about a wringing tool for mops having a box structure (1) without cover and bottom, without rods and levers inside for the oscillating moving of the pressure roller; its higher and lower openings enable the passing trough of the mops (12) with their supports for the rinsing in a whatever basin below the wringing tool. The oscillatory movement of the pressure roller (6) is carried out by means of a control hand lever (15) placed outwards and integral with an inner toothing gear (17) which meshes with a gear placed (16) inside and fitted on the shaft (8) which is integral with the oscillation levers (7) supporting the pressure roller (6) at its end. The contrast wall (3), which the roller (6) works on, can be bent. <IMAGE>
Patent AT-E346312-T1 (AT)
Inventor: ULLRICH MATTHIAS DR
IPC: G01R31/36
Filed: 2002-08-27
Granted: 2006-12-15
Abstract: The method involves finding two states of charge values by measuring continuous integration of battery current and a no load voltage. The measured no load voltage is compared with the empirical no load voltage characteristics. The highest value of the reliability of the two states is assessed based on the charge through put and amount of charge flown, to select the battery charge state.
Patent AT-E304121-T1 (AT)
Inventor: RICCO MARIO
IPC: F02M47/02
Filed: 2002-10-10
Granted: 2005-09-15
Abstract: The injector (5) has a hollow body (8) housing the body (11) of the metering valve (6), which has a discharge hole (14) for discharging the usual control chamber (33). The hole (14) comes out at a flat surface of the valve body (11), and is engaged by a flat surface (49) of a plate (48), under the control of an armature (25) of an electromagnet (26). The armature (25) is in the form of a disk, has substantially no stem, is connected to the hollow body (8) by a leaf spring hinge (39), and has a surface (54) having a spherical-bowl-shaped recess (56). A ball (50) is located between the recess (56) and another recess (52) carried by a second surface (51) of the plate (48). The valve body (11) is fixed to the hollow body (8) by a ring nut (23) of a given height. And, to cover the distance between the valve body (11) and the armature (25), a spacer member (64) is preferably formed in one piece with the valve body (11). <IMAGE>
Patent AT-E267270-T1 (AT)
Inventor: MANHARDT HARALD
IPC: B22D13/00
Filed: 2002-11-30
Granted: 2004-06-15
Abstract: To produce silver blank, with a silver content of at least 99.99 wt.% and an oxygen content of at most 20 microgram/g, the silver is melted together with 100-500 microgram/g calcium or aluminum under inert or reduction conditions. The calcium or aluminum can be added to the molten silver. The molten silver is poured into a mold and allowed to cool under atmospheric conditions. The system can use centrifugal or stand casting. The inert atmosphere uses carbon dioxide or argon and, during smelting, the silver can be covered by a carbon layer.
Patent AT-E392359-T1 (AT)
Inventor: STINTON ROBERT T
IPC: A41D13/012
Filed: 2002-12-12
Granted: 2008-05-15
Abstract: A diving suit has a suit body (12) made of a waterproof material. The suit body has an upper torso portion (14) configured for enclosing an upper torso of a diver. The upper torso portion includes a pair of sleeves (16) for enclosing the diver's arms and an opening for the diver's neck. The suit body has a trousers portion (21) for enclosing the diver' s legs. The upper torso portion further has an opening (24) sealed by a zipper. An upper segment of the opening extends diagonally across a front panel of the upper torso portion from one shoulder area of the upper torso portion. A lower segment of the opening partially encircles a waist area of the upper torso portion. This increases the effective length of the opening and makes it easier for the diver to put on and take off the diving suit. <IMAGE>
Patent AT-E321147-T1 (AT)
Inventor: JAMES LARRY CARLTON
IPC: C12N15/09
Filed: 2002-07-16
Granted: 2006-04-15
Abstract: The invention features a method of screening for an agent that inhibits intracellular phosphodiesterase 10A activity, comprising administering an agent to striatal medium spiny neurons and submaximally activating adenylate cyclase, administering an agent to striatal medium spiny neurons and submaximally activating guanylate cyclase, measuring cAMP generation and cGMP generation in the cells, and calculating the cAMP EC200 and the cGMP EC200, wherein the agent is identified as a PDE10A inhibitor if the ratio of cAMP EC200/ cGMP EC200 is comparable to the ratio produced by administration of papaverine under the same assay conditions. Also featured are rat PDE10A polynucleotide and polypeptide sequences.
Patent AT-E326036-T1 (AT)
Inventor: WINGEN NEAL T
IPC: G06F11/22
Filed: 2002-05-29
Granted: 2006-06-15
Abstract: An integrated circuit arrangement is reconfigurable in the field to operate in one of a plurality of modes, including a test mode, in response to mode-selecting codes presented via a temporary register in the circuit. In one example embodiment, an arrangement of integrated circuits includes a reconfigurable integrated circuit configured and arranged to operate in one of a plurality of modes. The reconfigurable integrated circuit includes a register adapted to store data for temporary use, with each operating mode of the reconfigurable circuit being selectable in response to mode-selecting data code. An interface circuit is electrically connected to the reconfigurable integrated circuit and is adapted to present the mode-selecting data code to the reconfigurable integrated circuit. A selection circuit is adapted to enable the interface circuit to pass mode-selecting data to the reconfigurable integrated circuit. The selection circuit is also adapted to detect when a series of data writes to the register corresponds to the mode-selecting data code and, in response, to reconfigure the integrated circuit to operate in one of the plurality of modes.
Patent AT-E480307-T1 (AT)
Inventor: JACOBS TERRY
IPC: A63B21/055
Filed: 2002-07-03
Granted: 2010-09-15
Abstract: A mogul skiing simulating device having a floating platform riding bearings on crank pins of two crankshaft assemblies while accommodating the changing distance between the two crankshaft pins during their rotation. The leader crankshaft assembly is about 30 to 35 degrees ahead of the follower. The platform is tethered by springs to its central support to maintain the platform in the correct relation to both pairs of crankshaft assemblies. The springs pull from a plastic bushings on each crankshaft pin toward the center of the platform. The tilt of the entire machine is higher in the rear to simulate downhill skiing. Cams may be attached to the front and rear crank journals which act upon the ends of a leaf spring to store and release energy. The crankshafts are turned by and electrically powered "V" drive. Railing allows the user to vary hand placement and body position.
Patent AT-E468638-T1 (AT)
Inventor: DAIBER ANDREW
IPC: H01S5/0687
Filed: 2002-07-05
Granted: 2010-06-15
Abstract: A laser having a grid generator that is configured such that the grid transmission peaks can be changed or varied during laser operation. The grid generator is tunable between at least two different, selectable grid spacings. The laser may be of various configurations, and may be a tunable external cavity laser having a channel selector in the external cavity. The laser may further comprise a tuner or tuning assembly operatively coupled to the grid generator and configured to adjust the grid generator to the selectable communication grids.
Patent AT-E438602-T1 (AT)
Inventor: VAN BROEKHOVEN EMANUEL
IPC: C07B37/04
Filed: 2002-05-23
Granted: 2009-08-15
Abstract: The present invention relates to a process for the catalytic alkylation of hydrocarbons comprising (i) reacting an alkylatable compound with an alkylation agent over a solid acid alkylation catalyst to form an alkylate, and (ii) regenerating said catalyst under mild regeneration conditions in the presence of hydrogen and hydrocarbon, wherein the hydrocarbon comprises at least a portion of the formed alkylate.