baber/WOPTO huggingface dataset:
Patent EP-3902910-A1 (EP)
Inventor: DUROY PIERRE-OLIVIER
IPC: C12N15/90
Filed: 2019-12-20
Abstract: Type-C endogenous retroviruses (ERVs) embedded in Chinese hamster ovary (CHO) cells were altered to modify the release of retroviral and/or retroviral-like particles in the culture supernatant. Although evidence for the infectivity of these particles is missing, their presence has raised safety concerns. 173 type-C ERV sequences that clustered into functionally conserved groups were identified. Transcripts from one type-C ERV group were identified to be full-length with intact open reading frames, and to have corresponding viral RNA genomes that were loaded into retroviral-like particles. Also, sequence analysis of the genomic RNA from viral particles indicated that they may result from few expressed ERV sequences. Disclosed herein is the disruption/alteration of the gag gene of the expressed ERV group using CRISPR-Cas9 genome editing. Comparison of CRISPR-derived mutations at the DNA and mRNA level led to the identification of a single ERV locus responsible for the release of viral RNA-loaded particles from CHO cells. Clones bearing a Gag loss-of-function mutation in this particular ERV locus showed a reduction of viral RNA-containing particles in the cell supernatant by over 250-fold. Notably, ERV mutagenesis did not compromise cell growth, cell size or recombinant protein production. Provided herein is a new strategy and cells, in particular engineered CHO cells, to mitigate potential contaminations from CHO endogenous retroviruses during biopharmaceutical manufacturing.
Patent EP-3906643-A1 (EP)
Inventor: KINI SHRINIVASA
IPC: H04L45/16
Filed: 2019-12-09
Abstract: A packet forwarding network may include spine and leaf switches that forward network traffic between end hosts that are coupled to the packet forwarding network. A controller may control the switches in the forwarding network to implement desired forwarding paths. The packet forwarding network may additionally include access switches that are directly connected to edge switches to form access switch groups, The access switches may also be controlled by the controller. End hosts may be coupled to access switches as well as leaf switches to extend the reach of the packet forwarding network. Additionally, the access switches may include access-leaf switches and access-edge switches to improve network routing capabilities and network flexibility.
Patent EP-3902757-A1 (EP)
Title: Modular waste management system
Inventor: MONTALBANO ANGELO
IPC: B65F1/10
Filed: 2019-12-26
Abstract: The invention relates to a modular system for managing one or more independent flows of waste, applicable to the selective collection, crushing and storage in segmented manner of waste containing different types of materials, such as glass, paper or cardboard, plastic, steel, and aluminium. The system comprises, for each given flow, separately and independently from the other flows: - an inlet E1 allowing bulk waste to be inserted, provided with closure means T1 that can take a closed position and an open position, allowing the inlet to be respectively closed and opened, - a storage chamber CS1 for crushed waste, - a crushing chamber CB1 arranged between the inlet and the storage chamber, comprising motorized means for mechanical crushing which allow the waste, received via the inlet and intended for the storage chamber, to be crushed. The system also comprises means for activating the crushing means, means for identifying (13) the type of waste, one or more sensors (5, 6, 7, 15, 16) that capture information relating to the environment and/or operation of the system, and electronic automatic control means (10) connected to the identification means, to the information sensors, to the closure means, and to the activation means, the control means being configured to control the passage of the closure means into either the open or closed positions, and to activate or deactivate the activation means, according to at least one piece of information received from the identification means and/or from at least one of the information sensors.
Patent EP-3831689-A1 (EP)
Inventor: KADOKAWA SHOTARO
IPC: B61H7/00
Filed: 2019-07-24
Abstract: An eddy-current rail brake device (1) includes a row of magnets (10), a supporting member (3), a case (4), and a lifting device (5). The row of magnets (10) includes a plurality of permanent magnets (2) that are arranged in a traveling direction of a railroad car. To the supporting member (3), the row of magnets (10) is mounted. The supporting member (3) has magnetism. The case (4) houses the row of magnets (10) and the supporting member (3) and includes a bottom portion (8) that faces the row of magnets (10) and is non-magnetic. The lifting device (5) raises and lowers the supporting member (3) inside the case (4) while the row of magnets (10) is kept facing the bottom portion (8). The eddy-current rail brake device (1) can prevent or reduce adhesion of a foreign object and can be reduced in size in a right-left direction.
Patent EP-3835695-A1 (EP)
Inventor: WEI DONG
IPC: F25D25/02
Filed: 2019-08-02
Abstract: Provided is a drawer assembly (100) for a refrigerator. The drawer assembly comprises: a drawer body (10), wherein the drawer body (10) comprises a bottom wall (11), a front end wall (12) and a rear end wall (13) which are arranged opposite each other in a drawing-in or drawing-out direction, and a first side wall (14) and a second side wall (15) respectively arranged at two sides of the front end wall (12) and the rear end wall (13), such that an accommodation cavity for placing an article is defined; and a slidable partition plate mechanism (20) configured to slide in the left and the right direction of the drawer body (10). The middle parts of top ends of the first side wall (14) and the second side wall (15) are respectively provided with a recess (101) for providing clearance when the slidable partition plate mechanism (20) is controlled to slide to the first side wall (14) or to the second side wall (15), such that the slidable partition plate mechanism (20) is attached to the first side wall (14) or to the second side wall (15) as much as possible. The drawer assembly (100) can provide a storage space in a maximized manner.
Patent EP-3841029-A1 (EP)
Title: Couvercle doté d'un élément de distribution
Inventor: BAIRD KYLE
IPC: A47G19/22
Filed: 2019-08-22
Abstract: L'invention concerne un couvercle destiné à un récipient. Le couvercle peut comprendre une paroi centrale et un élément de distribution comprenant un rabat de distributeur relié de façon pliable à la paroi centrale, une saillie s'étendant à partir du rabat de distributeur, et un rebord. Le rabat de distributeur peut être mobile vers une position de distribution dans laquelle le rabat de distributeur est espacé du rebord de façon à former au moins partiellement une ouverture de distribution. La saillie peut être en prise de verrouillage avec le rebord lorsque le rabat de distributeur se trouve dans la position de distribution.
Patent EP-3849209-A1 (EP)
Inventor: YU BING
IPC: H04R3/00
Filed: 2019-08-13
Abstract: The present invention relates to the technical field of mobile terminals. Disclosed are an audio signal processing method and apparatus, a device, and a storage medium. The method comprises: when detecting that 3.5 mm earphones are connected by means of a type-C plug of a transfer cable, a mobile terminal determines whether states of audio channels of an audio ground GND and a microphone MIC of the type-C plug are correct. When determining that the states of the audio channels of the GND and the MIC of the type-C plug are correct, the mobile terminal decides whether to enter an audio mode. If the mobile terminal decides to enter the audio mode, a low-resistance network for reducing channel impedance is controlled to connect in parallel to the GND.
Patent EP-3779697-A1 (EP)
Inventor: LIN MINGSHU
IPC: G06F9/54
Filed: 2019-08-16
Abstract: The present application provides a data processing method and apparatus, and an electronic device. The method includes: first predetermining a general event correlation configuration architecture, where the event correlation configuration includes a predetermined attribute configuration, a correlation data configuration, and an attribute configuration; processing the to-be-processed original event attribute based on these predetermined configurations, for example, filling data for the to-be-processed original event attribute, and obtaining the predetermined attribute based on the predetermined attribute configuration; obtaining correlation data according to the correlation data configuration; and performing, based on the predetermined attribute configuration, data conversion according to the predetermined correlation data configuration, the original event attribute, and the predetermined attribute, so as to obtain the event attribute corresponding to the current event.
Patent EP-3862286-A1 (EP)
Inventor: KUGE RAIZO
IPC: B65D30/18
Filed: 2019-09-30
Abstract: A square-bottomed packaging bag (1) of the present invention is a square-bottomed packaging bag formed by bending a one-piece soft packaging material and includes a quadrangular bottom surface (10), a front surface (20) and a rear surface (30) standing from two opposite sides of the bottom surface, and a left side surface (40) and a right side surface (50) connecting the front surface and the rear surface, in which each of the left side surface and the right side surface includes a first region (41, 51) positioned on the front surface side, a second region (42, 52) positioned on the rear surface side, and a side-surface-joining portion (43, 53) joining the first region and the second region.
Patent EP-3866803-A1 (EP)
Inventor: JEE JO-ANN
IPC: A61P31/18
Filed: 2019-07-31
Abstract: Pyrrole and pyridine derivatives and methods of synthesizing the derivatives/analogs are provided. In particular, the compounds are useful for the treatment of antiviral infections such as HIV and influenza.
Patent EP-3868074-A1 (EP)
Inventor: MISHRA RAJESH
IPC: H04L29/06
Filed: 2019-10-16
Abstract: Systems and methods for Radio Access Network dynamic functional splits are de-scribed. In one embodiment, a method may be disclosed for Radio Access Network dynamic func-tional splits, comprising: determining, by a user for a RAN, a first split of different functionalities between a central Unit (CU) and a Distributed Unit (DU), the functionalities including a Radio Resource Controller (RRC), a Packet Data Convergence Protocol (PDCP), a Radio Link Control (RLC); a Medium Access control (MAC), a Physical Layer (PHY), and a Radio Frequency Unit (RF); and wherein the system is able to provide different splits of the functionalities based on fac-tors such as user count, fronthaul capacity, fronthaul usage, required baseband processing capacity, and latency.
Patent EP-3866675-A1 (EP)
Inventor: LINDERS DAVID R
IPC: A61B5/00
Filed: 2019-10-15
Abstract: A system has a body with a base having a top surface with a receiving region to receive the bottom of a single foot. Among other things, the base may be in the form of an open or closed platform with a plurality of temperature sensors in communication with the top surface of the receiving region. The plurality of temperature sensors are within the receiving region and configured to activate after receipt of a stimulus applied to one or both the platform and the plurality of temperature sensors. A comparator is configured to form a temperature range as a function of the temperature value distribution and compare a percentage of the range size of the temperature distribution to a threshold value. An output produces ulcer information indicating the emergence of an ulcer or pre-ulcer when the percentage of the range size equals or exceeds the threshold value.
Patent EP-3868755-A1 (EP)
Inventor: WANG YONG
IPC: A61P29/00
Filed: 2019-10-17
Abstract: The present application relates to a compound as a TGF-β R1 inhibitor and application thereof. Specifically, provided are a compound of formula I, or an isomer, pharmaceutically acceptable salt, solvent, crystal, or prodrug thereof, preparation methods therefor, and pharmaceutical compositions comprising these compounds, and applications of these compounds or compositions in treating and/or preventing TGF-β R1-related diseases, such as cancer, tissue proliferation diseases, fibrosis, and inflammatory diseases. The compound represents a significant inhibitory activity for TGF-β R1 kinase, and is promising as a treatment agent for TGF-β R1-related diseases.
Patent EP-3872846-A1 (EP)
Inventor: CHOI JUCHAN
IPC: H01L33/06
Filed: 2019-10-08
Abstract: The present invention provides an apparatus for self-assembling a semiconductor light-emitting device, comprising: a fluid chamber having a space for accommodating a plurality of semiconductor light-emitting devices each having a magnetic body; a magnet for applying magnetic force to the semiconductor light-emitting devices while a substrate is disposed at an assembly position; a power supply unit for inducing electric field formation on the substrate such that the semiconductor light-emitting devices are seated at a predetermined position of the substrate in the process of moving by a position change of the magnet; and a fluid injector for injecting fluid into some of the semiconductor light-emitting devices seated on the substrate such that some of the semiconductor light-emitting devices are separated from the substrate.
Patent EP-3871756-A1 (EP)
Inventor: TANG WANFU
IPC: B01D53/54
Filed: 2019-10-21
Abstract: An exhaust gas treatment system, comprising an ozone purification system. The ozone purification system comprises an ozone amount control apparatus (209), used to control an amount of ozone so as to effectively oxidize gas components to be treated in exhaust gas, the ozone amount control apparatus (209) comprising a control unit (2091). By means of the present exhaust gas treatment system, particulate matter can be effectively removed from exhaust gas, and the system features a better exhaust gas purification treatment effect.
Patent EP-3857908-A1 (EP)
Title: Modular in-ear device
Inventor: RUGOLO JASON
IPC: H04R1/28
Filed: 2019-10-23
Abstract: An in-ear device includes a molding shaped to hold the in-ear device in an ear, and an audio package configured to emit sound. The audio package is structured to removably attach to the molding. An electronics package is structured to removably couple to the audio package and removably attach to the molding. The electronics package includes a controller to control the sound output from the audio package.
Patent EP-3847814-A1 (EP)
Inventor: ZHANG LI
IPC: H04N19/50
Filed: 2019-11-06
Abstract: Devices, systems and methods for digital video coding, which include geometric partitioning, are described. An exemplary method for video processing includes making a decision, based on a priority rule, regarding an order of insertion of motion candidates into a motion candidate list for a conversion between a current block of video and a bitstream representation of the video, wherein the current block is coded using a geometry partition mode; and performing, based on the decision and the motion candidate list, the conversion.
Patent EP-3876718-A1 (EP)
Inventor: MACNAUGHTAN MARISA
IPC: A01N59/00
Filed: 2019-10-29
Abstract: Sanitizing and disinfecting compositions with relatively low levels of free available chlorine, with good effectiveness against microbes. The composition may include less than 0.5% by weight hypochlorite or other free available chlorine level, at least one nonionic or zwitterionic surfactant, with a pH from 8 to 12.5. The composition is characterized by an R value of greater than 0 (e.g., greater than 0.5, or equal to 1), where R is defined as the sum of the concentration of any nonionic, zwitterionic, and cationic surfactants divided by the total surfactant concentration (and total surfactant concentration may include any surfactant aids). The compositions may exhibit at least a 3 -log reduction in M. bovis or C. diff population within 10 minutes (e.g., 4-6 minutes).
Patent EP-3881232-A1 (EP)
Inventor: HU DANYING
IPC: G06F3/0484
Filed: 2019-11-14
Abstract: A deep neural network provides real-time pose estimation by combining two custom deep neural networks, a location classifier and an ID classifier, with a pose estimation algorithm to achieve a 6D0F location of a fiducial marker. The locations may be further refined into subpixel coordinates using another deep neural network. The networks may be trained using a combination of auto-labeled videos of the target marker, synthetic subpixel corner data, and/or extreme data augmentation. The deep neural network provides improved pose estimations particularly in challenging low-light, high- motion, and/or high-blur scenarios.
Patent EP-3887377-A1 (EP)
Inventor: ZHANG YONGLIAN
IPC: C07D487/04
Filed: 2019-11-26
Abstract: In its many embodiments, the present invention provides certain 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives of Formula (I): or a pharmaceutically acceptable salt thereof, wherein ring A, R1, R2, and R4 are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutic agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and their use in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.
Patent EP-3891165-A1 (EP)
Inventor: ALTMAN MICHAEL D
IPC: C07H19/16
Filed: 2019-12-02
Abstract: A class of polycyclic compounds of general formula (I), wherein Base1, Base2, Y, Y a , X a , X a1 , X b , X b1 , X c , X c1 , X d , X d1 , R 1 , R 1a , R 2a , R 3 , R 3a , R 4 , R 5 , R 5a , R 6 , R 6a , R 7 , R 7a , R 8 , R 8a , and R 9  are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds (I).
Patent EP-3893367-A1 (EP)
Inventor: CHOI DAE HO
IPC: H02K1/28
Filed: 2019-11-12
Abstract: An embodiment relates to a motor which comprises: a housing; a cover disposed to cover the housing; a stator disposed in the housing; a rotor disposed inside the stator; a shaft disposed in the center of the rotor; a sensing magnet disposed at the end of the shaft; and a circuit board including a sensor for sensing the sensing magnet, wherein the sensor is disposed inside a hole formed through the cover. Therefore, in the motor, a hole is formed through the cover disposed to cover an opening of the housing and a sensor is disposed inside the hole, so that a size of an axis direction of the motor can be reduced.
Patent EP-3890945-A1 (EP)
Inventor: ROGREN PHILIP EUGENE
IPC: G03G15/16
Filed: 2019-11-22
Abstract: An electrophotographic three dimensional printer system, including at least one electrophotographic (EP) printing module employing multi-material EP printing technology. The printer system may also include one or more additional printer modules employing different patterning and deposition technology, such as powder bed and jetted binder technology. The EP printing module may be used to create a 3D object derived from a composite toner material that may comprise an engineering material treated with a triboelectric material. The composite toner material may be designed to undergo a post printing treatment wherein a triboelectric material may be separated from an engineering material and the engineering material may undergo a change.
Patent EP-3897751-A1 (EP)
Title: <sup2/>?     <sub2/>?18?     ?composés théranostiques à double mode marqués auf et leurs utilisations
Inventor: PERRIN DAVID
IPC: A61K51/10
Filed: 2019-12-18
Abstract: L'invention concerne un composé ou un complexe moléculaire. Le composé ou le complexe moléculaire comprend : un chélateur métallique configuré pour une chélation avec un isotope radioactif ou un isotope non radioactif ; et un fragment contenant du trifluoroborate (BF 3 ) configuré pour un échange  19 F/ 18 F ou un précurseur de celui-ci ; et facultativement un domaine de ciblage cellulaire.
Patent EP-4076943-A1 (EP)
Inventor: STUCZYNSKI RUSSELL P
IPC: B32B37/12
Filed: 2019-12-19
Abstract: Build-up of adhesive on process equipment is reduced or even eliminated by increasing the running temperature of process equipment used to guide substrates as they are conveyed along a system used to apply adhesive and form laminates. Preferably, the process equipment is heated to a temperature of at least about 5°C, preferably at least about 10°C, and most preferably at least about 15°C, above the crossover temperature of the adhesive, and at most about 60°C, preferably at most about 50°C, and most preferably at most about 45°C, above the crossover temperature. This method is particularly beneficial when using hot melt adhesives to form laminates with permeable substrates, such as low basis weight nonwovens, for use in disposable absorbent articles. A system for applying a hot melt adhesive to a substrate comprises a heater for providing heat to the process equipment and, optionally, a chiller for cooling the process equipment.
Patent EP-3904734-A1 (EP)
Inventor: HE YUCHEN
IPC: F16K1/42
Filed: 2019-12-17
Abstract: An electronic expansion valve (1-100) is provided. The electronic expansion valve (1-100) includes: a screw (1-31), a valve needle (1-22), and an elastic member (1-25). One end of the elastic member (1-25) acts on the screw (1-31) and the other end acts on the valve needle (1-22). A bearing (1-23) is arranged between the screw (1-31) and the valve needle (1-22). The bearing (1-23) has an inner ring and an outer ring. One of the screw (1-31) and the valve needle (1-22) is fixed with the inner ring of the bearing (1-23), and the other acts on the outer ring of the bearing (1-23) through the elastic member (1-25). An air conditioning system using the electronic expansion valve (1-100) is provided. In the electronic expansion valve (1-100), the bearing (1-23) is arranged between the valve needle (1-22) and the screw (1-31).
Patent EP-3907846-A1 (EP)
Inventor: HE LONG
IPC: H02J7/00
Filed: 2019-06-21
Abstract: Provided are a power battery pack and an electric vehicle. The power battery pack is fixed on the electric vehicle, and is configured to provide power for the electric vehicle. The power battery pack includes: a pack body; a plurality of cells, disposed in the pack body and disposed in the pack body; the cell having a length Lo, a width Ho, and a thickness Do, where at least one cell meets: L 0 >H 0 ≥D 0 , a length direction of the cell is arranged along a width direction of a vehicle body of the electric vehicle, and in the width direction of the electric vehicle, a sum of the length Lo of the cell and a size W of the vehicle body of the electric vehicle in the width direction meet: 46%≤L/W≤76%; or at least one cell meets: L 0 >H 0 ≥D 0 , a length direction of the cell is arranged along a length direction of a vehicle body of the electric vehicle, and in the length direction of the electric vehicle, the sum of the length Lo of the cell and a size X of the vehicle body of the electric vehicle in the length direction meet: 40%≤L/W≤76%.
Patent EP-3913678-A1 (EP)
Inventor: DO YOUNG RAG
IPC: H01L27/15
Filed: 2019-07-15
Abstract: A light emitting device may include: a plurality of first electrodes and a plurality of second electrodes disposed at positions spaced apart from each other in a first direction; a plurality of light emitting elements electrically coupled between a first electrode and a second electrode adjacent to each other among the first and the second electrodes; and a third electrode disposed at a preset position spaced apart from the first electrodes and the second electrodes. The third electrode may be electrically separated from the first electrodes and the second electrodes.