baber/WOPTO huggingface dataset:
Patent PT-675134-E (PT)
Inventor: PHILIBERT DANIEL
IPC: A61P43/00
Filed: 1995-03-29
Abstract: 20-(aminoalkylamino)-19-norpregna-1,3,5(10)-trien-3-ol cpds. of formula (I) and their acid addn. salts are new: R1, R2 = 1-12C alkyl or 7-15C aralkyl; or NR1R2 = 5- or 6-membered satd. heterocycle opt. contg. a further N, O or S heteroatom; R3 = 1-8C alkyl; n = 2-15; R4 - 1-12C alkyl; R5 = H, up to 12C acyl or 1-12C alkyl; the 17 and 20 asymmetric centres independently have R or S absolute configuration. In an example, 3.03 g (20S) (8 alpha , 9 beta , 13 alpha , 14 beta , 17 beta )-2- dimethylamino-N-(3-hydroxy-19-norpregna-1,3,5,(10)-trien-20-yl)- acetamide was added under inert gas at 20 degrees C. to a mixt. of 1.845g LiAlH4, 5.25g AlCl3 and 131 ml THF. The mixt. was refluxed for 24 hrs., cooled to 0-5 degrees C. and treated with 20 ml EtOAc then 100 ml satd. aq. NaCl. The suspension was filtered then successively taken up in water 16N HCl (80 ml/50 ml), filtered, taken up in 60 ml 60% EtOH/8 ml NEt3 and filtered. The soln. was treated with water for pptn. extd. with CH2Cl2, washed, dried, treated with active carbon and evapd. The dry residue (1.9g) was dissolved in 60 ml EtOHc/4 drops NEt3 for 15 mins. at reflux. The soln. was concd. to 30 ml and cooled at 0-5 degrees C. for 1 hr. The residue was recovered by centrifuge and dried to give 1.03 g (Ia), m.pt. 177 degrees C.. Ä alpha Üp = -80.6 degrees (c = 0.5%, EtOH).
Patent PT-742816-E (PT)
Inventor: TAHVONEN RISTO TAPIO
IPC: A01N63/30
Filed: 1995-01-27
Abstract: PCT No. PCT/FI95/00042 Sec. 371 Date Sep. 23, 1996 Sec. 102(e) Date Sep. 23, 1996 PCT Filed Jan. 27, 1995 PCT Pub. No. WO95/20646 PCT Pub. Date Aug. 3, 1995The present invention relates to biological control of plant diseases and concerns new microorganisms belonging to the genus Nectria, as well as their use for controlling fungal infections in plants. The invention also concerns compositions comprising new strains of the genus Nectria and their use for these purposes. The invention also provides a method of screening effective control organisms from microbial strains isolated from soil.
Patent PT-825943-E (PT)
Inventor: DURCHSCHLAG GERALD
IPC: B61L5/04
Filed: 1996-05-02
Abstract: PCT No. PCT/AT96/00087 Sec. 371 Date Feb. 9, 1998 Sec. 102(e) Date Feb. 9, 1998 PCT Filed May 2, 1996 PCT Pub. No. WO96/34786 PCT Pub. Date Nov. 7, 1996A device for setting railway switches includes a plurality of interlinked hydraulic switching devices (6) connected to a separate reversible hydraulic drive unit in a manner offset in the longitudinal direction of the rails, wherein the working volumes of the hydraulic cylinder piston aggregates (6) are connected to driving movement in same direction. The pistons (20) or plungers (11) include push-open valves (18) for travel limitation.
Patent PT-885358-E (PT)
Inventor: KEIKOV JURI
IPC: F04C3/06
Filed: 1996-12-13
Abstract: PCT No. PCT/EE96/00003 Sec. 371 Date Mar. 1, 1999 Sec. 102(e) Date Mar. 1, 1999 PCT Filed Dec. 13, 1996 PCT Pub. No. WO98/26182 PCT Pub. Date Jun. 18, 1998This invention may find use in applications such as pumps and other machines, it solves the problem of reduction of hydrodynamic resistance multiply and increases the capacity. The offered mechanim comprises of disc-shaped housing (1) with through hole (2), which is overlapped by mobile parts of rotary-piston group. Four chambers (6), formed by rotor (5) and pistons (11, 12), move in a circle inside the housing hole (2) in the plane of axle of the hole and run alternately along two sides of the housing. On running along one side they increase their volume, and along the other they reduce it, pumping over fluid through the said hole (2) in the housing. A rotary-piston group kinematically represents a modified Hooke joint. Shafts (4) are positioned at an angle. Sleeves of forks are changed into single arc-shaped half-sleeves, which are located directly on the shafts (one sleeve on each shaft). Cruciform has a spherical shape with two intersected circular canals and functionally the cruciform represents a rotor of the rotary-piston mechanism. Half-sleeves of shafts, located in the cruciform canals, functionally represent doubled pistons (11, 12). Inner surface of the through hole (2) in the housing and outer surface of members of the rotary-piston group (5, 11, 12) have spherical shape.
Patent PT-821462-E (PT)
Inventor: HORNER ROGER ERIC
IPC: H02K1/27
Filed: 1995-08-02
Abstract: An energy storage and conversion apparatus 1 comprisinga containment 5 defining a vacuum chamber 7,a substantially vertical shaft within the vacuum chamber 7,a stator 11 on the shaft 9, anda cylindrical rotor 13 which, in use, is driven by the stator 11 to store energy as kinetic energy of the rotor 13 and acts with the stator 11 as a generator to release energy,   wherein the rotor 13 is supported by the shaft 9 via an end cap 29, positioned at the upper end of the cylindrical rotor 13, which engages the shaft 9. The rotor 13 is suspended from a pin bearing 31 which is attached to an end cap 29. The pin bearing 31 sits in a bearing cup 37 mounted in a damper 39 at the end of the shaft 9. A magnet bearing 43 is provided at the lower end of the rotor 13 to assist in positioning the rotor 13 relative to the stator 11.
Patent PT-889877-E (PT)
Inventor: RUSSELL MARK ANDREW
IPC: C07C205/45
Filed: 1997-03-26
Abstract: The present invention relates to a class of compounds represented by the Formula I   <IMAGE>   or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the  alpha v beta 3 integrin.
Patent PT-975222-E (PT)
Title: Wettable or water-soluble granular agrochemical composition
Inventor: KOIKE MASAHIKO
IPC: A01N47/44
Filed: 1998-02-09
Abstract: The present invention provides a wettable or water-soluble granular agrochemical composition which comprises a guanidine derivative of the formula:wherein R1 represents a homocyclic or heterocyclic group which may optionally be substituted; n is 0 or 1; R2 represents hydrogen or a hydrocarbon group which may optionally be substituted; R3 represents a primary, secondary, or tertiary amino group; X represents an electron attractive group; or a salt thereof, an alkenylsulfonate and a carrier. The agrochemical composition has excellent disintegrability and dispersibility in water.
Patent PT-991371-E (PT)
Title: A method for treating dentures
Inventor: EDWARDS MARK IEUAN
IPC: A61K6/896
Filed: 1998-01-14
Abstract: The invention relates to a method for treating a denture, comprising passing the denture through the air interface of an aqueous composition comprising a polymeric coating agent, especially a silicone polymer, having a weight average molecular weight of 1,000 or greater. The invention further relates to the use of a denture bath in the method. Passing the denture through the interface in this way enhances the coating of the denture with the polymer, thereby delivering improved plaque prevention.
Patent PT-983246-E (PT)
Inventor: SHARP MATTHEW JUDE
IPC: C07D401/12
Filed: 1998-05-22
Abstract: Synthesis of the MDRI of formula (I) from intermediates of acridone acid of formula (II) and aminophenethyl isoquinoline of formula (III), via steps including coupling and conversion to yield the MDRI of formula (I).
Patent PT-1039905-E (PT)
Title: Pharmaceutical formulation comprising glycine as a stabilizer
Inventor: MCSHANE JAMES
IPC: C07D401/12
Filed: 1998-09-14
Abstract: The present invention provides pharmaceutical formulations suitable for intravenous injection comprising a lyophilized anti-ulcerative agent reconstituted in isotonic solutions suitable for intravenous administration, such as 5 % dextrose or 0.9 % sodium chloride. The solutions are brought to a pH of between about 9 and about 12, preferably between about pH 10 and 11, by a glycine-sodium hydroxide buffer. Such formulations are chemically and physically stable, and do not significantly change color, for at least between about 6 and about 12 hours at room temperature, and are stable to color change for from between about 24 and 48 hours if kept at 5  DEG C.
Patent PT-1051785-E (PT)
Inventor: DELAFORCE STEPHEN ROBERT
IPC: H02G1/08
Filed: 1999-01-19
Abstract: A pipe threading arrangement includes a launch body (13) and a parachute (15) within tube (12). The parachute is launched into pipe (2) via slide valve (1) and brings with it a threading cable (19). At a remote location within the pipe (2) the parachute is stopped by a catch arm (8) with associated catch finger (5). The parachute is deflated and retrieved, together with the threading cable, via the slide valve into the catch body (4).
Patent PT-1071438-E (PT)
Inventor: VARLEY CLAIRE ALISON
IPC: A61P31/04
Filed: 1999-04-26
Abstract: Stabilized dried pharmaceutical compositions dispersible in aqueous liquid or injection comprise (i) virus e.g. for use as a vaccine or vector, preferably a herpesvirus, e.g. attenuated or genetically disabled infectious herpes simplex virus or varicella zoster virus, (ii) polysaccharide, e.g. dextran, and/or a source of mixed aminoacids of vegetable or bacterial origin, (iii) a buffer, and (iv) a mono- or oligo-saccharide or derivative thereof.
Patent PT-1071779-E (PT)
Title: Vertebrate patched-2 protein
Inventor: SAUVAGE FREDERIC J DE
IPC: C12P21/02
Filed: 1999-04-02
Abstract: The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, antibodies, vectors and host cells expressing, immunoadhesins, agonists and antagonists to patched-2.
Patent PT-1131356-E (PT)
Title: Monoclonal anti alpha-d (itgad) antibody for use in the treatment of cns injuries caused by trauma
Inventor: GALLATIN MICHAEL W
IPC: A61K38/00
Filed: 1999-11-16
Abstract: Methods to inhibit inflammation and macrophage infiltration following spinal cord injury are disclosed along with methods to modulate TNFalpha release from cells expressing alphad are disclosed.
Patent PT-1133379-E (PT)
Inventor: TSELESIN NAUM N
IPC: B24D7/06
Filed: 1999-11-23
Abstract: A method for making a sintered article (14) comprising providing a plurality of individual blocks (19) of sinterable matrix material, arranging said blocks in abutting relationship to form an assembly of said blocks in a sinter mold wherein said assembly comprises a plurality of said blocks extending in at least one direction thereof and sintering said assembly under pressure in the mold to form an integrated sintered article. The blocks may contain abrasive particles to provide a sintered abrasive article and individual abrasive segments (15, 16, 17) may be extracted from the article.
Patent IE-41997-L (IE)
Title: Manufacturing plastics pipes
IPC: B29C48/12
Filed: 1976-01-13
Abstract: An apparatus for forming a plastic pipe having a circular cross-section and elongated longitudinal channels in the pipe wall is disclosed. A mass of synthetic plastic material is pressed through an annular space defined by inner and outer annular supports, the annular space having a plurality of spaced pin supports concentrically disposed therein and regulating the quantity of material flow through the annular space, depending on the shape of the pin supports, by selectively moving the walls of the annular supports closer to each other. In a particularly advantageous embodiment, either the wall of the inner annular support or the wall of the outer annular support, or both, are moved closer to each other in the area between adjacent pin supports.
[US4323339A]
Patent IE-44773-L (IE)
Title: Theophylline compositions
IPC: A61M5/31
Filed: 1977-02-14
Abstract: An enzymatic intralenticular cataract treatment for removal of nuclear cortical and subcapsular regions of the cataractous lens through enzymatic digestion thereof which comprises introduction of a concentrated solution of mixed exogenous enzymes into the nuclear and cortical regions of a cataractous lens, and after enzymatic digestion removing the liquefied cataractous material. The procedure allows removal of the nuclear, cortical and subcapsular portions of a cataractous lens through a very tiny incision in the eye and lens capsule, leaving all other structures within the eye intact.
[US4078564A]
Patent IE-34259-L (IE)
Title: Ribbon spool for business machines
IPC: B41J33/00
Filed: 1970-05-28
Abstract: 1,255,721. Ribbon spools. WALTER GRAFTON & SON Ltd. 3 June, 1970 [13 June, 1969], No. 30042/69. Heading B8M. [Also in Division B6] A spool for a business machine e.g. a typewriter, adding machine, computer, is furnished with a prong 6 moulded integrally with the spool hub 1 and extending circumferentially over a portion of the hub to provide a gap between the hub and prong, and with a projection 9 moulded integrally with the hub and extending therefrom in the gap to limit deformation of the prong under the stress of a ribbon wound on the spool, the prong 6 being shaped to permit attachment of the ribbon to be wound on the spool. The prong 6 may be provided on a flat portion 5 formed in the hub surface or may project from a shoulder on the hub and shaped to form a continuation of the hub surface. The prong may also be provided with barbs. In a preferred embodiment, two prongs 6 are provided on the hub, which prongs face in opposite directions. The two prongs may be separate or mounted on a pedestal projecting from the hub surface. The spool is preferably made from thermoplastic material.
[GB1255721A]
Patent IE-41117-L (IE)
Title: Making glass by the float process
IPC: C03B18/16
Filed: 1975-04-23
Abstract: A radiation reflector in the inlet portion of a flat glass forming chamber is used to reflect sufficient heat that is radiated from the glass immediately after delivery onto molten metal in the chamber back to the glass so that the glass loses heat relatively more rapidly through its bottom surface than through its top surface and is maintained sufficiently hot immediately following delivery onto the molten metal to have an average viscosity between 103 and 105 poises during its initial residence on the molten metal and to have an initial rate of temperature decline that is slow relative to its rate of temperature decline thereafter. The glass produced is of improved optical flatness.
[US3928010A]
Patent IE-900955-L (IE)
Title: Pyrrolidines
IPC: C07D409/06
Filed: 1990-03-16
Abstract: Pyrrolidine muscarinic receptor antagonists, particularly useful in the treatment of irritable bowel syndrome, of the formula:- <CHEM> and their pharmaceutically acceptable salts, wherein Y is a direct link, -CH2-, -(CH2)2-, -CH2O- or -CH2S-; R is -CN or -CONH2; and R<1> is a group of the formula:- <CHEM> where X and X<1> are each independently O or CH2; m is 1, 2 or 3; and "Het" is pyridyl, pyrazinyl or thienyl. u
[EP0388054A1]
Patent FI-812171-L (FI)
Inventor: BRIGGS PETER JAMES
IPC: C08J5/08
Filed: 1981-07-09
Abstract: A fibrous composite material of essentially two-dimensional form in the form of individual fibres, sheets or layers comprising combustible fibres and lamellae of a layer mineral of size below 50 microns, a method for the manufacture of the fibrous composite materials by applying lamellae of a layer mineral to the fibres preferably from suspension followed by removal of the liquid phase of the suspension, and use of the fibrous composite materials for the fire-protection of substrates.
Patent FI-844840-L (FI)
Inventor: LING TOMMY
IPC: C02F1/52
Filed: 1984-12-07
Abstract: The present invention relates to a method and apparatus for distributing a water purifying chemical, particularly a flocculating-agent concentrate, throughout a stream of water to be purified. In accordance with the method, the concentrate is introduced into the stream of water transversally to its direction of flow under the action of rotational motion, to achieve a distribution time of at most one second.
Patent FI-850595-L (FI)
Inventor: STOPPELMANN GERSCHON
IPC: D03D13/00
Filed: 1985-02-13
Abstract: 1. Cloth, particularly fabric or felt for draining and drying paper webs in paper-manufacturing machines, comprising at least two lengthwise areas (A, B; C, D, E), characterized in that at least one of said lengthwise areas (A; D) is provided with a first type of binding or weave between the warp threads (7) and the weft threads (10) whereby the part of warp threads (7) passing above the weft threads (10) and facing the paper web forms a first contact surface with said paper web, and at least another lengthwise cloth area (B; C, E) is provided with a type of weave between the warp threads (7) and the weft threads (10) which differs from the first type of weave and whereby the part of warp threads (7) passing above the weft threads (10) and facing the web paper forms a contact surface therewith which differs from said first contact surface.
Patent IE-33304-L (IE)
Title: Adhesive compositions
IPC: C07C67/00
Filed: 1969-08-26
Abstract: 1301645 Stabilized cyanoacrylate adhesive compositions INTERCONTINENTAL CHEMICAL CO Ltd 21 Aug 1970 [26 Aug 1969] 40406/70 Heading C2C [Also in Division C4] An adhesive composition comprises at least one purified monomeric ester of 2-cyanacrylic acid of formula CH 2 = C(CN)-COOR, where R is a C 1-16 alkyl or alkenyl group, a cyclohexyl group or a phenyl group, together with as stabilizer, at least one organic sulphonic acid having a pKa not exceeding 2 8 in a total concentration of from 0 0005 to 0 5% by weight of the composition.
[GB1301645A]
Patent IE-901279-L (IE)
Title: High gloss base paper
IPC: B32B27/10
Filed: 1990-04-09
Abstract: - Papermaking. 
<??>- The base comprises, on at least one face:
 - a first coat of a conventional coating slip deposited at a rate of 3 to 25 g/m<2>,
 - at least one superposed coat deposited at a rate of 1 to 10 g/m<2> and based on conventional pigments, at least one conventional binder and gloss pigments in a proportion of at least 20 % of parts by weight of the traditional pigment charge and corresponding to a particle size of between 0.05 and 1 micrometre and, preferably, close to 0.5 micrometre. 
<??>- Application to the production of a high-gloss paper.
Patent IE-791437-L (IE)
Title: Alkyl derivatives of c-076 compounds
IPC: A61K31/355
Filed: 1979-08-08
Abstract: The invention provides derivatives of C-076, which is a series of macrolides, having certain hydrocarbon substituents. The hydrocarbon substituents in general are alkyl groups which may be straight or branched and may optionally be substituted with phenyl. The substituted C-076 compounds are prepared by various procedures depending upon the position of the reaction site, and the particular C-076 compound being substituted. The compounds thus produced are of formula: 
<CHEM>
 where the broken line indicates that a single or a double bond is present in the 22(23) position; R1 is hydroxy, loweralkanoyloxy or hydrocarbonoxy and is present only when the broken line indicates a single bond; R2 is iso-propyl or sec-butyl; R3 is hydrogen, methyl, loweralkanoyl or a hydrocarbon;
 R is hydrogen, loweralkanoyl, a hydrocarbon, 
<CHEM>
 where R4 is hydrogen, loweralkanoyl or a hydrocarbon, and
 R5 is hydrogen or methyl; and the said hydrocarbonoxy group of R1 is an alkoxy of from 1 to 10 carbon atoms or an alkoxy of from 1 to 10 carbon atoms or an alkoxy of from 1 to 10 carbon atoms substituted by phenyl and the said hydrocarbon groups of R and R4, which are the same or different, are alkyl of from 1 to 10 carbon atoms or alkyl of from 1 to 10 carbon atoms substituted by phenyl; and the said hydrocarbon group of R3 is an alkyl of from 2 to 10 carbon atoms or an alkyl of from 1 to 10 carbon atoms substituted by phenyl; provided that at least one of the R, R1, R3, and R4 groups is or contains a hydrocarbon group or R5 is methyl. They have profound anthelmintic, insecticidal, ectoparasiticidal and acaracidal activity and compositions for such uses are also disclosed.
Patent IE-32839-L (IE)
Title: Urea-antibiotic adducts
IPC: A23K20/195
Filed: 1968-11-27
Abstract: 1,244,019. Macrolide-urea adducts. ELI LILLY & CO. 4 Dec., 1968 [4 Dec., 1967 (2); 15 July, 1968], No. 57629/68. Heading C2A. Novel aldehydic-rnacrolide bis-ureas wherein the aldehyde group of 1 molecule of an appropriate macrolide is combined with 2 molecules of a urea of formula wherein Am is -NH-R, R being phenyl, tolyl, halophenyl or trifluoromethylphenyl; or R<SP>1</SP> and R<SP>11</SP> being independently hydrogen, C 1 to C 4 alkyl or C 3 to C 4 alkenyl and the sum of their carbon atoms not exceeding 4, are prepared by reacting in a neutral solvent, at least 2 moles of the urea with 1 mole of the macrolide. The macrolides may be tylosin, macrosin, desmycosin, lactenocin, carbomycin, carbomycin B, niddamycin, spiramycins A, B, C and D or leucomycins A 1 to A 8 . Ureas may be urea or N-methyl-; N,N-diethyl-; N-n-butyl-; N- allyl-; N-phenyl-; N-(p-chlorophenyl)-; N-(otolyl)-; or N- (p .trifluoromethylphenyl)-urea. The compounds are preferably prepared by adding the macrolide or a salt thereof to a saturated aqueous or alcoholic solution of the urea at room temperature, allowing to stand, diluting with water and bringing to pH 9, and saturating the solution with sodium chloride to precipitate the required product. This is filtered off, dissolved in chloroform, the solution washed with water, and the chloroform evaporated off; the product is finally recrystallized, e.g. from aqueous acetone. Dihydro (ketone reduced) tylosin bis-urea is prepared by reducing tylosin bis-urea in ethanolic solution with sodium borohydride, and is subsequently hydrolysed by treatment with aqueous ethanol at pH 5À0 and 90‹ C. for ¢ hour to give the novel antibiotic dihydro- (ketone reduced) tylosin, this product being extracted from the reaction solution with methyl - ene dichloride at pH 5À0 to 5À5. Alternatively, the dihydro (ketone-reduced) bis-urea is hydrolysed to give the novel antibiotic dihydro/ketone-reduced) desmycosin by aqueous hydrolysis at either pH 2À8 and room temperature for 4 days or pH 3À6 and 100‹ C. for 1¢ hours, the said antibiotic being extracted from the hydrolysate with methylene dichloride at pH 7 to 8. Pharmaceutical compositions comprise one or both of the antibiotics dihydro(ketone-reduced) tylosin and dihydro(ketone-reduced) desmycosin together with a carrier. Veterinary compositions for administering to ruminants comprise an aldehydic-macrolide bis-urea as defined above together with a carrier which may be an animal feedstuff.
[GB1244019A]
Patent IE-39876-L (IE)
Title: Machine for applying labels to bottles
IPC: B65C3/16
Filed: 1974-07-18
Abstract: This disclosure deals with a machine for transferring indicia (such as decalcomanias) from an elongated web or carrier strip to generally cylindrical articles (such as bottles) at a high rate of speed. The articles are moved along a transport path and means is provided to turn the articles as the articles are moved through an indicia transferring portion of the path. The web is moved in the same direction and at substantially the same speed as the articles moving in said transferring portion, and the outer surface of each article is rolled against an indicium by turning the article. Article spacing means is provided at the entrance to said portion to adjust the spacing of the articles. Sensor means is also provided for sensing the indicia and the articles entering said portion, and for actuating said spacing means to adjust the article spacing.
[US3928115A]