baber/WOPTO huggingface dataset:
Patent CA-1311179-C (CA)
Title: Element and method for determination of creatinine or creatine
Inventor: DETWILER RICHARD L
IPC: G01N33/70
Filed: 1987-11-06
Granted: 1992-12-08
Abstract: -i-ELEMENT AND METHOD FOR DETERMINATION      OF CREATININE OR CREATINE Abstract of the Disclosure An analytical element for determining creatinine or creatine is disclosed.  The element reduces the interference of lidocaine metabolites. The element comprises an absorbent carrier material containing 200-1,200 I.U./m2 of the enzyme creatinine amidohydrolase, 35,000-65,000 I.U./m2 of the enzyme creatine amidinohydrolase and 2,000-3,500 I.U./m2 of the enzyme sarcosine oxidase and a leuco dye which is capable of providing a detectable dye in the presence of hydrogen peroxide and a peroxidative substance, said creatine amidinohydrolase being present in a manner such that it is substantially inert to said leuco dye; and said creatinine amido-hydrolase being present in a rate limiting amount and all three of said enzymes are present at a pH of about 6.5 to 6.9.
Patent CA-1337112-C (CA)
Inventor: JONES FRANK R
IPC: G01N33/564
Filed: 1987-11-20
Granted: 1995-09-26
Abstract: Extracorporeal perfusion using an immunoadsor-bent material specific for disease-related antigens is used for therapy of the disease state.  Antibodies to particular antigens, including tumor antigens, viral antigens, and bacterial antigens, are used to prepare the immunoadsorbent material.  Patients suffering from the disease are then treated by removing a flow of blood, separating the blood into plasma cellular components, passing the plasma through the immunoadsor-bent material, recombining the treated plasma and cellular components of the blood, and returning the treated blood to the patient.
Patent CA-1322621-C (CA)
Inventor: PANUSH SOL
IPC: C08K7/00
Filed: 1987-11-17
Granted: 1993-09-28
Abstract: ABSTRACT    Automotive costing compositions are disclosed.  The compositions comprise a metallic or a metallic-like pigment and a metal oxide pigment, wherein the metal oxide pigment has a particle size of about 20 nm to about 30 nm. The coating compositions exhibit high chromaticity with excellent downflop.  The coating compositions also have an opalescent appearance.
Patent CA-1304147-C (CA)
Title: Method for depth imaging multicomponent seismic data
Inventor: WHITMORE NORMAN D JR
IPC: G01V1/28
Filed: 1988-02-24
Granted: 1992-06-23
Abstract: ABSTRACT         The present invention relates generally to a method of geophysical exploration and more particularly to a novel method for imaging multicomponent seismic data to obtain better depth images of the earth's subsurface geo-logical structure as well as better estimates of compres-sional and shear wave interval velocities.  In particular, measures are obtained of imparted seismic wavefield poten-tials incident on reflecting interfaces in the earth's subsurface and of resulting seismic wavefield potentials scattered therefrom.  The incident and scattered seismic wavefield potentials are employed to produce time-depen-dent reflectivity functions representative of the reflect-ing interfaces.  By migrating the time-dependent reflectivity functions, better depth images of the reflecting interfaces can be obtained.  For a dyadic set of multicomponent seismic data, the dyadic set of multi-component seismic data are partioned so as to separate the variously coupled incident and reflected wavefield poten-tials in the recorded multicomponent seismic data.  The incident and reflected wavefield potentials are cross-correlated to form time-dependent reflectivity functions.          The time dependent reflectivity functions are then iter-atively migrated according to a model of wavefield poten-tial velocities of propagation to obtain better estimates of the compressional and shear wave interval velocity.          The migrated reflectivity functions can then be stacked to produce better depth images of the earth's subsurface geo-logical structures.
Patent CA-1311080-C (CA)
Inventor: CUZIN DANIEL
IPC: C08G69/44
Filed: 1988-02-24
Granted: 1992-12-01
Abstract: Polyester amides and polyether thioether ester amides of the formula <IMAGE>   wherein A is a polyamide sequence, R1 and R2 can be the same or different and each represents a linear or branched C2 to C98 alkyl radical, m is an integer between 1 and 50, and n is one or greater; and the process of making such amides by reacting specific diols with a dicarboxylic polyamide having terminal acid functional groups.
Patent CA-1328457-C (CA)
Inventor: GARDNER JOSEPH H
IPC: C07C239/00
Filed: 1988-03-08
Granted: 1994-04-12
Abstract: NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING INFLAMMATION AND PAIN          ABSTRACT OF THE DISCLOSURE The present invention relates to beta-aminoethyl-substituted phenyl compounds, especially beta-aminoethoxy-substituted phenyl compounds, having the general structure:                 wherein: the W-X moiety is selected from -C(O)NH-, -C(S)NH-, -S(O)2NH-, -NHC(O)O-, -NHC(S)O-, -NHC(O)NH-, and -NHC(S)NH- wherein either available bond of the W-X moiety is bonded to the R moiety and the remaining bond is attached to the benzyl carbon atom; Z is selected from hydrogen, hydroxy, and methoxy; R1 is selected from hydrogen, hydroxy, alkyl esters of hydroxy having from about 1 to about 5 carbon atoms, alkyl having from about 1 to about 5 carbon atoms, and alkoxy having from about 1 to about 5 carbon atoms; each R2 is inde-pendently selected from hydrogen, halogen, unsubstituted or substituted alkyl having from about 1 to about 5 carbon atoms, substituted or unsubstituted aryl, and carboxylate, or two R2 moieties are covalently bonded to form a substituted or unsub-stituted alkyl ring having from about 3 to about 7 carbon atoms in the ring; R is a C6-C24 alkyl moiety; and Y is selected from -O-, -S- and -NH-.      The present invention also relates to pharmaceutical compo-sitions comprising a safe and effective amount of a compound of the present invention and a pharmaceutically-acceptable carrier. The present invention further relates to methods for producing analgesia and reducing inflammation, in humans and lower ani-mals, by administering the compounds or compositions of the present invention. In addition, the present invention relates to methods for making compounds of the present invention and intermediates useful in these synthesis methods.
Patent CA-1315775-C (CA)
Title: 4-demethoxy-4-amino-anthracyclines
Inventor: CARUSO MICHELE
IPC: C07C225/34
Filed: 1988-04-20
Granted: 1993-04-06
Abstract: ABSTRACT     Anthracycline glycosides of the general formula (I):            I   wherein R1 represents a hydrogen atom or a hydroxyl group, one of R2 and R3 represents a hydrogen atom and the other of R2 and R3 represents a hydrogen atom or a hydroxyl group; and pharmaceutically acceptabls acid addition salts thereof are antitumor agents.  These glycosides may be prepared from a daunomycinone derivative of formula (II):       in which the 4-amino group is protected.  4-Demethoxy-4-amino-daunomycinone (I) and an earlier intermediate in its preparation, 4-demethoxy-4-amino-7-deoxy-daunomycinone (IX), can be diazotised followed by mild reduction to form 4-demethoxy-daunomycinone or 4-demethoxy-7-deoxy-daunomycinone respectively.  4-Demethoxy-daunomycinone can be converted into another antitumor anthracycline glycoside, 4-demethoxy-daunorubicin.
Patent CA-1332413-C (CA)
Title: Camptothecin derivatives and process for preparing same
Inventor: SAWADA SEIGO
IPC: C07D471/14
Filed: 1988-06-23
Granted: 1994-10-11
Abstract: S P E C I F I C A T I O N            Title:    NEW CAMPTOTHECIN DERIVATIVES AND PROCESS           FOR PREPARING SAME            ABSTRACT OF THE DISCLOSURE      New camptothecin derivatives, useful as antitumor agents or intermediates therefor, of the general formula (I)                (I) wherein X is a lower alkyl group, and R is a hydrogen atom or the grouping -COY  where Y is a linear or branched unsubstituted C1-C18alkyl group; a lower alkyl group substituted by a halogen atom or a lower alkylthio, amino, acylamino, hydroxyl, lower alkoxy, aryloxy or lower alkoxy-carbonyl group; a C3-C19 alkenyl, C3-C19 alkynyl or C3-C8 cycloalkyl group; a C3-C8 cycloalkyl group substituted by an acylamino-lower alkyl group; an N-acylpyrrolidyl group; a phenyl group; a phenyl group substituted by a halogen atom or a trifluoromethyl, nitro, amino, lower alkoxycarbonyl, lower alkyl, phenyl or lower alkoxy; a cinnamyl group; a benzyl group; a naphthyl group; a pyridyl group; a furyl group; or a thienyl group, as well as acid addition salts an?     quaternary ammonium salts thereof, and a process for preparing the new camptothecin derivatives by subjecting 7-ethylcamptothecin to the treatment with an N-di-ethylenediamine followed by acylation.
Patent CA-1324124-C (CA)
Title: Catalyst for olefin polymerization and processes for its production
Inventor: KIOKA MAMORU
IPC: C08F10/00
Filed: 1988-09-01
Granted: 1993-11-09
Abstract: ABSTRACT           The solid catalyst of this invention for olefin polymerization comprises a compound of a transition metal of Group IV of the periodic table and an aluminoxane as catalyst ingredients.  The catalyst is characteristic in that it has a high specific surface area, and shows very high polymerization activity on the homopolymerization or copolymerization of olefins.  Polymers obtained by using the catalyst of the invention have a high bulk density, a uniform particle size, a low fine powder content and a narrow molecular weight distribution, and in the case of copolymers, a narrow composition distribution as well.
Patent CA-1317187-C (CA)
Title: Thixotropic aqueous liquid automatic dishwashing detergent composition
Inventor: AHMED FAHIM U
IPC: C11D3/37
Filed: 1988-10-27
Granted: 1993-05-04
Abstract: PATENT     THIXOTROPIC AQUEOUS LIQUID AUTOMATIC  DISHWASHING DETERGENT COMPOSITION                 ABSTRACT OF THE DISCLOSURE   Thixotropic aqueous liquid automatic dishwashing detergent composition with improved anti-filming and anti-spotting properties and method of using the detergent composition. The detergent composition comprises silica anti-filming agent, polyacrylate polymer builder, inorganic builder salts, chlorine bleach, bleach-stable detergent and a thixotropic thickener. The compositions provide reduced filming and spotting on dishware, glassware, china and the like, particularly in hard water, and remain stable against phase separation.
Patent CA-1311973-C (CA)
Title: Non-dispersible vermiculite products
Inventor: BRUNGARDT CLEMENT L
IPC: C04B30/00
Filed: 1988-11-15
Granted: 1992-12-29
Abstract: NON-DISPERSIBLE VERMICULITE PRODUCTS     Abstract of the Disclosure A process for improving the water resistance of shaped articles formed by removing the water from an aqueous dispersion of vermiculite lamellae containing a cationic polyamine or an anionic polyacrylamide, and the shaped articles so formed, are disclosed.
Patent CA-1339219-C (CA)
Title: Polymeric cationic dyes
Inventor: TANIGUCHI KOICHI
IPC: D21H21/28
Filed: 1988-11-18
Granted: 1997-08-05
Abstract: The invention is concerned with novel cationic dyes having the general formula:      Q-(NH-A-CH=CH-B)n wherein the units of formula -NH-A-CH=CH-B are the same or different; n is 2 or 3; A is a benzene ring optionally substituted by a halogen atom, a C1-C4 alkyl or C1-C4 alkoxy group; B is a radical derived from a N-heterocyclic compound having a 5-and/or 6- membered mono- or bicyclic structure with an active methyl or methylene group, and quaternised by a C1-C4 alkyl, hydroxy (C2-C4) alkyl or benzyl group; and Q is the residue of a cross-linking agent selected from the group consisting of phosgene, halogenated triazines and halogenated pyrimidines. The dyes of the invention are particularly useful for dyeing paper.
Patent CA-1332073-C (CA)
Inventor: BOTELER WILLIAM C
IPC: H02H9/04
Filed: 1988-11-23
Granted: 1994-09-20
Abstract: SURGE SUPPRESSION MODULE            Abstract of the Disclosure A surge suppression module for providing existing wiring devices  with  a  surge  suppressing  element  for  protection against transient surges of voltage in a power circuit.  The surge  module  includes  a  universal  support  member  that accommodates   variously   voltage-rated   surge   suppressing elements and various covers that accommodate different female wiring devices to be mounted therein.  The surge module also includes an alarm for detecting an electrical malfunction in the  surge  suppressing element  and  an  indicator  light  for indicating  proper  electrical  functioning  of  the  surge suppressing element.
Patent CA-1297932-C (CA)
Title: Ground fault current protective device
Inventor: SCHUELLER PIERRE
IPC: H01H83/02
Filed: 1988-12-06
Granted: 1992-03-24
Abstract: ABSTRACT OF THE DISCLOSURE:            A ground fault trip unit of the three-pole type, comprises a fourth  conductor  passing  through  the  differential transformer.  The fourth conductor is connected to terminals located on a different face from that of the terminals of the other three conductors.  The same ground fault trip unit can be associated with a three-pole breaking device,  in which case the fourth conductor is not use, and with a four-pole device whose fourth pole is connected to the fourth conductor of the ground fault trip unit.
Patent CA-1307558-C (CA)
Inventor: DRAKE LAWRENCE V
IPC: F24D3/14
Filed: 1989-01-11
Granted: 1992-09-15
Abstract: ABSTRACT OF THE DISCLOSURE        An electric radiant heating system for heating building interior living and working space.  The system comprises an electric resistance heating cable embedded in a cementitious thermal mass for transferring thermal energy to the thermal mass when an electric current is applied to the cable.  The system utilizes a wall-mountable line voltage thermostat control to detect the temperature of the surrounding air, compare is to a selectable reference temperature, and perform a number of functions automatically depending on the results of the temperature comparison.  High limit sensors, composed of bimetal strips, detect the temperature of the electric heating cable, sending a signal to the control means to interrupt power to the electric heating system when the electric resistance heating cable reaches a predetermined temperature. Cable-retaining hardware secures the electric resistance heating cable at regularly spaced intervals to the subfloor.  The hardware holds portions of the cable above the subfloor to help suspend the cable in the cementitious underlayment layer.  The cable is entirely suspended and surrounded by the underlayment during pouring of the cementitious slurry so that the cable does not contact the subfloor.
Patent CA-1332029-C (CA)
Inventor: ANDOH KAZUTO
IPC: G03C7/413
Filed: 1989-01-17
Granted: 1994-09-20
Abstract: ABSTRACT OF THE DISCLOSURE A method  for  continuously  processing  an  imagewise exposed silver halide color photographic material with a color developer containing at least one aromatic primary amine color developing agent is disclosed, in which said color developer contains at least one compound selected from the group consisting of a compound represented by formula (I):                                            (I) wherein R1, R2, and R3 each represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted  aryl  group,  or  a  substituted  or unsubstituted heterocyclic group; R4 represents a hydrogen atom,  a hydroxyl group,  a substituted or unsubstituted hydrazino  group,  a  substituted  or  unsubstituted  alkyl group,  a  substituted  or  unsubstituted  aryl  group,  a substituted  or  unsubstituted  heterocyclic  group,  a substituted or unsubstituted alkoxy group, a substituted or  unsubstituted  aryloxy  group,  a  substituted  or unsubstituted  carbamoyl  group,  or  a  substituted  or unsubstituted amino group; or R3 and R4 are taken together to form a heterocyclic group;  X1 represents a divalent group; and n represents 0 or 1, provided that when n is 0, R4  represents  an alkyl  group,  an  aryl  group,  or  a heterocyclic group, and a compound represented by formula (II):                                             (II) wherein R5 represents a substituted alkylene group;  and R6, R7, R8, and R9, which may be the same or different, each  represents  a  hydrogen  atom,  a  substituted  or unsubstituted  alkyl  group,  or  a  substituted  or unsubstituted aryl group, and said color developer is replenished at a replenishment rate of  from 20  to 120 m? per m2 of  the photographic material.  The photographic material does not suffer from a variation of photographic characteristics when processed in continuous running even at a low replenishment rate of a color developer.
Patent CA-1337337-C (CA)
Title: Acidic polycyclic ether antibiotic having anticoccidial and growth promotant activity
Inventor: DIRLAM JOHN PHILIP
IPC: A61K31/70
Filed: 1989-02-06
Granted: 1995-10-17
Abstract: An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53708.  This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.
Patent CA-1313960-C (CA)
Title: Flexible contact lens for enhanced movement on the eye
Inventor: AMES KEITH S
IPC: B29L11/00
Filed: 1989-02-15
Granted: 1993-03-02
Abstract: ABSTRACT OF THE DISCLOSURE     A flexible contact lens (20) is disclosed as having a central power portion (24), a peripheral flange portion (27), and an externally concave transition portion (26) joining the central portion and the flange portion, whereby the flange portion extends outwardly from the central portion in the manner of a hat brim.  The inner edge of the peripheral flange is thereby raised from the eye surface to facilitate movement of the lens over the limbal region of the eye.  The extent of the peripheral flange forward from the eye surface promotes eyelid contact to enhance movement of the lens on the eye.  In a second embodiment (40), the lens further includes an externally convex transition portion (45) joining the central power portion (44) and the externally concave transition portion (46) to facilitate lens handling.    The invention also includes a method of producing such a flexible contact lens including the steps of a) forming a plastic mold on a tool which is a positive pattern of one surface of the desired lens, the resulting mold being a negative pattern of that surface, b) placing unpolymerized fluid material in the mold, c) rotating the mold to spread the fluid material at a desired thickness over the inner surface of the mold, d) polymerizing the fluid material by appropriate means such as heat or ultra violet radiation, and e) machining the opposite surface of the polymerized material to the desired lens configuration.
Patent CA-1324180-C (CA)
Inventor: CSEPREGI KAROLY
IPC: A63C5/11
Filed: 1989-02-21
Granted: 1993-11-09
Abstract: ABSTRACT         A sailboard (1) for sailing on snow or ice with a conventional articulated hand held sail means (2,3,15 and 16) mounted on the sailboard has an top side (40) and an underside (41), an upturned bow portion (42), a platform portion (43) and an upturned stern portion (44).  The underside has at least one longitudinal runner (45) and preferrably two such runners located sufficiently within and under the perimeter of the top side to provide balanced gliding and to permit the sailboard to be rolled laterally on the outermost of said runner(s) while maneuveuring.  Each runner glides longitudinally but has low resistance to lateral slippage except towards the rear of each said runner which is shaped to resist lateral slippage.  For ice conditions, a blade is provided.  As the sailboard pitches fore and aft the blade pivots to remain flat on the ice.
Patent CA-1331134-C (CA)
Inventor: TAN LARRY U L
IPC: C07K16/00
Filed: 1989-04-04
Granted: 1994-08-02
Abstract: ABSTRACT OF THE DISCLOSURE Lymphocytosis  promoting  factor  (LPF)   and filamentous hemaglutinin  (FHA)  are  isolated from   e growth medium of the Bordatella pertussis  organism and purified by selecting adsorbing the LPF and FHA on a selective adsorbing medium, such as filter aids or gel filtration media, at low ionic strength and subsequently removing the adsorbed LPF and FHA at using an aqueous medium of high ionic strength, either simultaneously or sequentially.   Prior to desorbtion of the LPF and FHA, the adsorbing medium may be contacted with an aqueous solution of a non-ionic detergent, which enables the LPF and FHA subsequently desorbed to be substantially free from contamination by lipopolysaccharides  (LPS).   The LPF and FHA may by further purified on hydroxyapatite. The  LPF  and  FHA  may  be  detoxified  separately  or together by contacting with a cross-linking agent, such as glutaraldehyde or formaldehyde, in the presence of an anti-aggregation  agent.    The  resulting purified  and detoxified  LPF  and  FHA may be used to  formulate a vaccine against pertussis.
Patent CA-1311730-C (CA)
Title: Scroll apparatus with pressure regulation
Inventor: RIFFE DELMAR R
IPC: F04C18/02
Filed: 1989-05-10
Granted: 1992-12-22
Abstract: PATENT     Title SCROLL APPARATUS WITH PRESSURE REGULATION                 Inventor Delmar R. Riffe Abstract In a scroll compression apparatus having an orbiting scroll, a frame with a pressure regulation chamber adjacent the orbiting scroll wherein the frame includes a spring biased annular seal and a pressure responsive device in a discharge aperture through the frame for maintaining constant pressure in the pressure regulation chamber.  Preferably, the frame includes an annular groove of rectangular cross-section accommodating a relatively smaller annular seal also of rectangular cross-section.  An annular seal spring having a first planar surface and a second planar surface is disposed in the annular channel to bias the annular seal.  The pressure responsive device has a first element exposed to discharge fluid pressure and a second element exposed to fluid at suction pressure such that the pressure differential serves to operate a piston for increasing or decreasing the flow area of the discharge aperture from the pressure regulation chamber.
Patent CA-1322642-C (CA)
Inventor: CURRY HERBERT L
IPC: C08G63/64
Filed: 1989-05-18
Granted: 1993-10-05
Abstract: COEXTRUDED PRODUCTS WITH IMPROVED WEATHERABILITY     ABSTRACT OF THE DISCLOSURE           A coextruded moisture resistant polycarbonate article has a relative thin moisture resistant, polyphthalate-carbonate layer adhered to a relatively thick aromatic polycarbonate corelayer.  The coextruded article has the high degree of transparency of aromatic polycarbonates and the moisture resistance and haze resistance of polyphthalate-carbonate.  Coextruded sheet and film of the present invention may be subsequently thermoformed without losses in the desirable properties thereof.
Patent CA-1332822-C (CA)
Title: Mailer with oversized insert and method of making
Inventor: SCHMIDT ERIC
IPC: B31B41/00
Filed: 1989-05-19
Granted: 1994-11-01
Abstract: Disclosed is a series of connected mailers comprising exterior plies consituting an envelope front and back, a plurality of equally spaced lines of transverse perforation defining a series  of envelopes each having the front and back plies connected along all four sides thereof, a plurality of insert plies within each envelope, at least one of said plies being transversely folded on itself.  Also disclosed is a method of manufacture   for such mailers.