baber/WOPTO huggingface dataset:
Patent NZ-553431-A (NZ)
Title: Neublastin variants with decreased heparin binding
Inventor: ROSSOMANDO ANTHONY
IPC: A61K38/17
Filed: 2005-08-18
Abstract: Disclosed is a polypeptide comprising an amino acid sequence that is at least 80% identical to amino acids SEQ ID NO: 1, wherein the amino acid sequence comprises amino acids other than arginine substituted at the positions corresponding to position 48 and position 49 of SEQ ID NO: 1, wherein the polypeptide, when dimerized, binds to a complex containing GFRalpha3 and RET, and wherein the polypeptide exhibits decreased heparin binding as compared to the wild to type neublastin protein of SEQ ID NO: 1. Further disclosed in the use of the polypeptide as described to form a dimer, conjugate, fusion protein or expression vector.
Patent NZ-553845-A (NZ)
Title: Netting material with reflective or luminescent marker
Inventor: LIN RONEN
IPC: A01F15/00
Filed: 2004-09-07
Abstract: Disclosed is a netting which includes knitted longitudinal franze ribbons and interconnecting transverse schuss ribbons which zigzag laterally between the longitudinal franze ribbons and form a series of triangular openings. At least one reflective or luminescent indicator strip is threaded or knitted into the netting so as to extend over at least a part of the length of the netting adjacent to at least one of the longitudinal franze ribbons, at least one of the interconnecting transverse schuss ribbons, or both.
Patent NZ-554405-A (NZ)
Title: Method for preparing crystalline and crystal-like forms of purified lipopeptides
Inventor: KEITH DENNIS
IPC: A23K20/195
Filed: 2001-12-17
Abstract: Disclosed is a method for preparing daptomycin, comprising the steps of: providing an amorphous form of daptomycin; and crystallizing the daptomycin from a crystallization solution comprising a cation from a salt, a buffer, an organic precipitant, and a low molecular weight alcohol.
Patent NZ-554495-A (NZ)
Title: Bariatric device and method with lumen exerting force on eosophagus or stomach areas
Inventor: BAKER RANDAL S
IPC: A61M29/00
Filed: 2005-10-13
Abstract: A bariatric device and method of causing satiety in a patient includes providing a body having a wall defining a lumen. The wall is sized to conform to the shape and size of the abdominal portion of the esophagus and/or at the esophageal-gastric junction and/or the proximal cardiac portion of the stomach of the patient. The wall is adapted to exert radial pressure on the abdominal portion of the esophagus and/or the esophageal-gastric junction, and/or the proximal stomach, or cardia, of the patient. This influences the neurohormonal feedback mechanism present at the distal esophagus and the cardia to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food.
Patent NZ-560599-A (NZ)
Title: Method for joining multi-layered pipe
Inventor: LILLEY GRAHAM
IPC: B29C65/02
Filed: 2006-02-24
Abstract: A plastic bodied pipe coupling 90 for joining or capping a multi-layered pipe, includes a spigot portion 92b and one or more shroud portions 92a secured on respective ends of the spigot portion by receipt of an annular rim 94 of the shroud portion into an annular groove 93 provided in an annular protrusion 93a on the outer annular surface of the spigot portion. The annular protrusion 93a is provided with a recess 93b of corresponding proportions to a protrusion 94a provided on the annular rim.
Patent NZ-562250-A (NZ)
Title: Producing methane by contacting a gas stream with a hydrogen souce in the presence of a catalyst
Inventor: DIAZ ZAIDA
IPC: C10L3/08
Filed: 2006-04-24
Abstract: Disclosed is a method of producing methane. The method comprises providing formation fluid from a subsurface in situ conversion process; separating the formation fluid to produce a liquid stream and a first gas stream; and contacting the first gas stream with a hydrogen source in the presence of one or more catalysts to produce a second gas mixture. The first gas stream comprises carbon monoxide, olefins, and hydrogen, and the second gas mixture comprises methane. The hydrogen source comprises hydrogen present in the first gas stream.
Patent NZ-563125-A (NZ)
Title: Lipid extract of mussels and method for preparation thereof
Inventor: MACRIDES THEODORE
IPC: A61K35/618
Filed: 2006-06-01
Abstract: A method for the preparation of a lipid extract of mussels is disclosed, which comprises the steps of (i) digesting mussel tissue with a protease enzyme (enzymatic-digestion) for a time and under conditions suitable to release a lipid fraction from the tissue, and (ii) recovering said lipid fraction.
Patent NZ-563758-A (NZ)
Title: 19,26,27-Trinor-1alpha,25-dihydroxyvitamin D3 compounds
Inventor: DELUCA HECTO F
IPC: A61K31/59
Filed: 2006-05-02
Abstract: Disclosed is a compound of formula 1, wherein X1, X2, and X3 are independently H or hydroxy protecting groups, and R1 or R2 are H or alkyl or together form an alkene group as described in the specification. Also disclosed is the use of the compound for treating a biological disorder where a rise in serum calcium is undesirable, selected from renal osteodystrophy, secondary hyperparathyroidism, psoriasis, type I diabetes, lupus, rheumatoid arthritis, or a cancer selected from leukemia, colon cancer, breast cancer, or prostate cancer.
Patent NZ-565990-A (NZ)
Title: Therapies for chronic inflammatory demyelinating polyneuropathy using interferon-beta
Inventor: SANDROCK ALFRED
IPC: A61K/
Filed: 2003-09-26
Abstract: Disclosed is then use of IFN-beta therapeutic in the manufacture of a medicament for the treatment of a chronic demyelinating motor neuropathy in a mammal, wherein said medicament is formulated for administration of said IFN-beta therapeutic via a non-subcutaneous parenteral route.
Patent NZ-567191-A (NZ)
Title: Heterocyclic substituted pyridine derivatives and antifungal agent containing same
Inventor: TANAKA KEIGO
IPC: C07D413/14
Filed: 2006-10-30
Abstract: Disclosed is a pyridine compound of formula (I), or a salt thereof, wherein the substituents are defined in the specification. Also disclosed are pharmaceutical compositions comprising said compound, a medicament comprising said compound, an antifungal agent comprising said compound and the use of said compound for the manufacture of an antifungal agent.
Patent NZ-577744-A (NZ)
Title: Method of diagnosing breast cancer, colon cancer, melanoma and Alzheimer?s disease by detecting changes in the ultrastructure of keratin or collagen from a skin or nail sample by X-ray diffraction
Inventor: JAMES VERONICA
IPC: G01N33/483
Filed: 2008-01-03
Abstract: Disclosed is a method of detecting prostate cancer, melanoma, colon cancer, breast cancer or Alzheimer's disease in a subject, the method comprising exposing a nail sample of the subject to fibre X-ray diffraction, and detecting changes in the ultrastructure of the nail sample.
Patent NZ-580328-A (NZ)
Title: 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators
Inventor: LABRIE FERNAND
IPC: A61P5/28
Filed: 2008-04-11
Abstract: Disclosed are steroid compounds of formula I, salts and N-oxides thereof, and methods for their preparation. The compounds are useful as antiandrogenic compounds and selective androgen receptor modulators. Also disclosed is the use of the compound for treating or reducing the risk of developing prostate cancer, benign prostatic hyperplasia, polycystic ovarian syndrome, acne, seborrhoea, hirsutism, androgenic alopecia, precocious puberty, diseases related to loss of androgenic stimulation, muscle atrophy and weakness, skin atrophy, bone loss, anemia, arteriosclerosis, cardiovascular disease, loss of energy, loss of well-being, type 2 diabetes, or abdominal fat accumulation.
Patent NZ-585293-A (NZ)
Title: Garment having coolant in waffle design tubing matrix
Inventor: DEAKIN GLEN
IPC: A62B17/00
Filed: 2008-11-17
Abstract: A cooling garment (200), comprising at least one tubing matrix (225) in the form of a waffle design (226) for location of a coolant. At least one reactant for forming the coolant is located within the at least one tubing matrix.
Patent NZ-586514-A (NZ)
Title: Conjugates of anti-rg-1 antibodies for cancer treatment
Inventor: KING DAVID J
IPC: A61K47/48
Filed: 2008-11-26
Abstract: Disclosed are Anti-RG-1 antibodies, antibody fragments, or antibody mimetics conjugated to partner molecules, such as drugs, radioisotopes, and cytotoxins, wherein the partner molecule exerts its effect regardless of whether the RG-1 bound conjugate is internalized within a targeted cell, are useful for treating cancers.
Patent NZ-587630-A (NZ)
Title: Novel tetrahydroisoquinoline derivative
Inventor: UTO YOSHIKAZU
IPC: C07D413/12
Filed: 2009-03-24
Abstract: Disclosed are tetrahydroisoquinoline derivatives represented by general formula (I), or pharmacologically acceptable salts thereof. Also disclosed is the use of the compounds of general formula (I) for treating or preventing diseases such as, those whose symptoms are altered by inhibiting acyl-coenzyme A, adiposity, obesity, hyperlipidemia, hypertriglyceridemia, lipidosis, insulin resistance syndrome, impaired glucose tolerance, diabetes, diabetic complications (including diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, and diabetic macroangiopathy), cataract, gestational diabetes mellitus, nonalcoholic steatohepatitis, polycystic ovary syndrome, arteriosclerosis, atherosclerosis, diabetic atherosclerosis, ischemic heart disease, or bulimia.
Patent NZ-594493-A (NZ)
Title: Addition salts of amines containing hydroxyl and/or carboxylic groups with amino nicotinic acid derivatives as dhodh inhibitors
Inventor: PEREZ GARCIA JUAN BAUTISTA
IPC: A61K31/455
Filed: 2010-03-11
Abstract: 594493 Disclosed herein is a pharmaceutically acceptable crystalline addition salt of an amine containing one or more hydroxyl and/or carboxylic groups with an amino nicotinic derivative of formula (I), wherein the variables are defined in the specification; a pharmaceutical composition comprising said salt and one or more therapeutic agents selected selected from anti-TNF-alpha monoclonal antibodies, TNF-alpha Antagonists, calcineurin (PP-2B) Inhibitors / INS expression inhibitors, IL-1 receptor antagonists, anti-CD20 monoclonal antibodies, p38 Inhibitors, NF-kappaB (NFKB) activation inhibitors, dihydrofolate reductase (DHFR) inhibitors, JAK3 Inhibitors, MEK inhibitors, S1 P1 agonists, Interferons, inmunomodulators, and adenosine aminohydrolase inhibitors; and the use of said salt or pharmaceutical composition in the treatment of a pathological condition or disease susceptible to amelioration by inhibition of dihydroorotate dehydrogenase, such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondilytis, multiple sclerosis, Wegener's granulomatosis, systemic lupus erythematosus, psoriasis and sarcoidosis. Embodiments of the amino nicotinic derivative include the following: 2-{ [3'-ethoxy-3-(trifluoromethoxy)-1,1'-biphenyl-4-yl]amino} nicotinic acid, meglumine salt, and 2-[(3,5-difluoro-2-methyl-1,1'-biphenyl-4-yl)amino]nicotinic acid, tromethamine salt.
Patent NZ-594823-A (NZ)
Title: Settable material impregnated claoth comprises two layers of cloth linked by fibres and with the space between filled with a settable powdered material
Inventor: CRAWFORD WILLIAM CAMPBELL
IPC: E04C5/07
Filed: 2010-01-29
Abstract: 594823 A impregnated flexible cloth that can be set to become rigid or semi-rigid, comprises a first face 10, a second face 12 separated from the first face 10 by a space, self-supporting linking fibres 14 extending between the first and second faces that maintain the first and second face in a spaced-apart arrangement, and a powder material allocated in the space between the first and second faces. The material is capable of setting to a rigid or semi rigid solid on the addition of a liquid or on exposure to radiation. At one or more edges of the cloth, the first and second faces are connected by an elastic yarn 26 that is shorter than the self-supporting linking fibres, thereby at least partly closing the space at the edge of the cloth.
Patent NZ-601871-A (NZ)
Title: Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
Inventor: CHUNTHARAPAI ANAN
IPC: C07K16/28
Filed: 2006-11-30
Abstract: Disclosed is an antibody that specifically binds to IL-22, wherein the antibody is: (a) an antibody produced by a hybridoma selected from 3F11.3 (ATCC Accession No. PTA-7312), and hybridoma 8E11.9 (ATCC Accession No. PTA-7319); (b) an affinity matured form of the antibody of (a); (c) an antigen-binding fragment of the antibody of (a) or (b); or (d) a humanised form of the antibody of (a), (b), or (c). Also disclosed is the use of said antibody in the preparation of a pharmaceutical composition for alleviating a disorder characterised by skin inflammation.
Patent NZ-605851-A (NZ)
Title: Method for producing flexographic printing plates using uv-led irradiation
Inventor: SCHADEBRODT JENS
IPC: G03F1/00
Filed: 2011-07-12
Abstract: Disclosed is a method for producing flexographic printing plates, wherein a photopolymerizable flexographic printing element is used as the starting material, said element comprising at least the following, arranged one on top of the other: a dimensionally stable carrier; and at least one photopolymerizable layer forming a relief, which comprises at least an elastomeric binding agent, an ethylenically unsaturated compound, and a photoinitiator; optionally a rough UV-transparent layer, comprising at least a particulate substance; and a layer that can be digitally imaged. The method according to the invention comprises the following steps: (a) generating a mask by imaging the layer that can be digitally imaged; (b) illuminating the photopolymerizable layer forming the relief through the mask, using actinic light, and photopolymerizing the image areas of the layer; and (c) developing the photopolymerizable layer by washing out the non-photopolymerized areas of the layer forming the relief with an organic solvent or by thermal development. Said method is characterized in that step (b) comprises two illumination steps (b-1) and (b-2), wherein in a first step (b-1), illumination is carried out using actinic light having an intensity of more than 100 mW/cm from a plurality of UV LEDs, and subsequently, in a second step (b-2), illumination is carried out using actinic light having an intensity of less than 100 mW/cm from a UV radiation source other than UV LEDs. Also disclosed is an apparatus when used in the method.
Patent NZ-610065-A (NZ)
Title: A centrifugal separator and an outlet element for a centrifugal separator
Inventor: REIFF HENRIK
IPC: B04B1/20
Filed: 2011-11-14
Abstract: A centrifugal separator comprises a rotating body (40) rotating in use around an axis (45). The rotating body comprises a bowl (41), which comprises a base (42) at one longitudinal end of the bowl, the base defining a rear longitudinal area. An outlet passage (47) extends through the base and an outlet housing (55) is provided in the rear longitudinal area. The outlet housing is communicating with the outlet passage to receive liquid therefrom and the outlet housing has an outlet opening (63) discharging in use liquid from the rotating body. The outlet opening comprises a weir edge (65) defining in normal use a level of a surface of a liquid in the bowl. The outlet housing is rotatable around an adjustment axis (59) and the outlet opening is placed in a side wall (57) offset from the adjustment axis.
Patent NZ-611886-A (NZ)
Title: Methods of creating and screening dna-encoded libraries
Inventor: WAGNER RICHARD W
IPC: C40B70/00
Filed: 2010-02-16
Abstract: Disclosed is a method of identifying a compound that binds a biological target, said method comprising (a) contacting one or more compounds with a target under conditions suitable for at least one compound to bind to said target; (b) removal of said one or more compounds that do not bind to said target; and (c) identification of said at least one compound bound to said target; wherein said one or more compounds comprise a bifunctional linker bound to an initiator oligonucleotide at the 5’ end of said initiator oligonucleotide, and at least one identifier oligonucleotide; wherein said bifunctional linker or initiator oligonucleotide is modified to increase solubility of said compound in organic conditions.
Patent NZ-612573-A (NZ)
Title: A composition for detecting biofilms on viable tissues
Inventor: BOWLER PHILLIP GODFREY
IPC: G01N33/68
Filed: 2011-11-30
Abstract: A staining composition for use in making biofilm detectable on viable tissue wherein the composition preferentially stains the biofilm rather than the viable tissue and comprises a preservative and a staining agent in a quantity effective to stain said biofilm and render it detectable, wherein the staining agent is selected from Rose Bengal, Alcian Blue, Rhodamine 123, Rhodamine B, Fast Green, and Erythrosine. Also disclosed is a kit of parts for use in the detection of biofilms.
Patent NZ-708741-A (NZ)
Title: Tablets with improved acceptance and good storage stability
Inventor: HAMANN HANS-JÜRGEN
IPC: A61P33/10
Filed: 2013-12-17
Abstract: The present invention relates to tablets for animals, allowing for high amounts of flavor and good storage stability. Tablets of the invention comprise at least 28% meat flavouring and at least 2% sodium croscarmellose. Tablets of the invention demonstrate a stable disintegration profile following long-term storage.
Patent NZ-709486-A (NZ)
Title: Solid solution compositions and use in chronic inflammation
Inventor: BREW JOHN
IPC: A61K47/44
Filed: 2014-01-14
Abstract: The present specification discloses a solid solution pharmaceutical composition comprising one or more therapeutic compounds in an amount of about 0.1% to about 40% by weight of the pharmaceutical composition; and one or more hydrophobic hard fats in an amount of at least 30% by weight of the pharmaceutical composition, the one or more hydrophobic hard fats being solid at 20°C and comprising glycerolipids having a triglyceride at least one fatty acid with a C12-C24 carbon chain length; wherein when the one or more therapeutic compounds is a therapeutic compound having a free acid or base with a logP of 2.2 to 3.0, one or more stabilizing agents are present, wherein when the one or more therapeutic compounds is a therapeutic compound salt with a logP of 2.2 or less, one or more neutralizing agents are present, wherein the solid solution pharmaceutical composition does not comprise a surfactant; and wherein the solid solution pharmaceutical composition is formulated to be a solid at a temperature of about 15°C or lower and has a melting point of 30°C or higher.
Patent NZ-711441-A (NZ)
Title: Flow generator message system
Inventor: OATES JOHN DAVID
IPC: A61M16/00
Filed: 2006-10-13
Abstract: A flow generator (10) for delivering breathable gas to a patient includes a processor (18) coupled with operation sensors (34) and a user interface (20). The processor (18) is programmed to generate at least one of time-based or event-based messages relating to at least one of flow generator operation, flow generator service, flow generator use, patient health, peripheral devices and services, patient treatment, and reminders. Time-based messages are generated at predetermined time intervals based on either time of use or elapsed time. The event-based messages are generated based on signals from the operation sensors. The user interface (20) is configured to deliver the messages to at least one of a display (22), a flow generator service provider, the patient and a physician. By this system, operation of the flow generator is facilitated and enhanced.
Patent NZ-715246-A (NZ)
Title: Improved process for production of monoclonal antibodies
Inventor: PATEL SANJAY
IPC: C12N5/00
Filed: 2014-07-07
Abstract: The present invention provides for an improved process to obtain substantial amount of monoclonal antibodies with desired profile of charged variants. The process involves initially culturing the mammalian cells at a suitable temperature and subsequently reducing the temperature and optionally by simultaneous addition of suitable amino acid(s) during production of the desired molecule. The present invention provides also provides for an antibody having desired profile of glycans prepared with said with improved process.
Patent NZ-717972-A (NZ)
Title: Method for pretreatment of wastewater and recreational water with nanocomposites and bridging polymers
Inventor: RYTWO GIORA
IPC: B01D21/01
Filed: 2014-08-14
Abstract: A method for pretreatment of wastewater or recreational water with substantial reduction of total suspended solids and turbidity in a very short time is provided comprising treatment with nanocomposites and a bridging agent. The nanocomposite (a) is comprised of an anchoring particle (ai) and a polymer (aii) while the bridging agent is selected from a polyanionic polymer (bi) a polycationic polymer (bii) or a second nanocomposite (biii) comprising (a) and (bi) or (bii).
Patent NZ-722235-A (NZ)
Title: Fluid atomizer, nozzle assembly and methods for assembling and utilizing the same
Inventor: BIGGS JAMES
IPC: B05B1/34
Filed: 2015-02-18
Abstract: A fluid atomizer disclosed herein generally addresses the need to improve known structures for delivering a fluid. The fluid atomizer (12) comprises a proximal portion (18) including: a body (24); an intermediate portion (20) including legs (34) connected to the body (24) of the proximal portion (18); and a distal portion (22) including a shoulder portion (42) connected to the legs (34) of the intermediate portion (20), wherein the shoulder portion (42) includes a distal surface (46), wherein the intermediate portion (20) is between the proximal portion (18) and the distal portion (22), and wherein the distal portion (22) further includes a head portion (54) adjacent to the shoulder portion (42), wherein the head portion (54) includes a distal surface (56) and a side surface (58) between the distal surface (46) of the shoulder portion (42) and the distal surface (56) of the head portion (54), and wherein the side surface (58) of the head portion (54) includes a plurality of radially inwardly projecting recesses (60), each of the recesses (60) extending along an entire height of the head portion (54) from the distal surface (46) of the shoulder portion (42) to the distal surface (56) of the head portion (54).
Patent NZ-722403-A (NZ)
Title: Pharmaceutical compositions for the treatment of inflammatory disorders
Inventor: DE WEER MARC
IPC: A61K31/541
Filed: 2015-02-04
Abstract: The present invention discloses pharmaceutical compositions comprising: a compound according to Formula (I) useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.