baber/WOPTO huggingface dataset:
Patent CA-2957717-A1 (CA)
Title: Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein
Inventor: WITTRUP KARL DANE
IPC: A61K47/64
Filed: 2015-08-12
Abstract: The present invention provides a method of treating cancer with a combination of IL- 2 and an integrin-binding-Fc fusion protein. The methods of the invention can be applied to a broad range of cancer types.
Patent CA-2958615-A1 (CA)
Inventor: KLINT KNUD ERIK
IPC: B09C1/06
Filed: 2015-09-24
Abstract: Disclosed is a method for introducing a liquid, preferably aqueous, into a volume of a porous medium (typically clay or clay-rich soil), which has a matrix hydraulic conductivity below 10-7 m/s, comprising establishing at least one frozen section and at least one non-frozen section of said volume and introducing said liquid into said non-frozen section. Also disclosed is a method for remediation of a volume of such a porous medium as well as a system/assembly suitable for carrying out said method.
Patent CA-2958677-A1 (CA)
Inventor: LI ALFRED
IPC: B32B17/04
Filed: 2015-08-13
Abstract: A durable, moisture-resistant gypsum product is provided with smooth furnish which comprises a laminated glass fiber mat (30) in which glass fibers (12) are compressed and cross-linked with a thermosetting polymeric resin (20). Methods for making these gypsum products and glass fiber mats are provided as well.
Patent CA-2959963-A1 (CA)
Inventor: BLUNK DIRK
IPC: A62D1/02
Filed: 2015-09-02
Abstract: The invention relates to a fire fighting foam concentrate comprising a first surfactant, the first surfactant having an acid group as well as an oligosilane unit and/or oligosiloxane unit. The invention further relates to a method for extinguishing fires, comprising the steps of: providing a fire fighting foam concentrate; adding the fire fighting foam concentrate to water to obtain a mixture and bringing the fire into contact with the mixture; wherein the fire fighting foam concentrate is a fire fighting foam concentrate according to the invention. A further object of the invention is the use of a surfactant as an additive to fire fighting foams and/or fire fighting foam concentrates, the surfactant comprising an acid group as well as an oligosilane unit and/or oligosiloxane unit. An example is the following: (formula)
Patent CA-2961874-A1 (CA)
Inventor: CARON FRANCOIS
IPC: G09B23/30
Filed: 2017-03-24
Abstract: The present disclosure relates to a body cavity simulator. The body cavity simulator is adapted for simulating medical instrument insertion procedures.  The body cavity simulator comprises a duct, a plurality of haptic mechanisms and a plurality of sensors. The duct defines an insertion path adapted for receiving and guiding translation of a simulated medical instrument. Each haptic mechanism is positioned at a haptic point along the insertion path.  Each haptic mechanism is adapted for applying a resistive haptic force to the simulated medical instrument. Each sensor is co-located with one of the haptic mechanisms. Each sensor is adapted for detecting the simulated medical instrument at the haptic point and generating simulated medical instrument positioning data.
Patent CA-2963314-A1 (CA)
Title: Solutions de sels de metal trialcalin d'acides aminocarboxyliques, leur fabrication et leur utilisation
Inventor: REINOSO GARCIA MARTA
IPC: C07C229/24
Filed: 2015-10-07
Abstract: La présente invention concerne une solution aqueuse contenant de 60,5 à 75% en poids de mélange de sels de métal trialkalin d'énantiomères L et D de l'acide méthyl glycine diacétique (MGDA), ledit mélange contenant principalement l'isomère L en un excès énantiomérique (e.e.) compris entre 3 et 97%, lesdits sels de métal trialcalin ayant la formule générale [CH3-CH(COO)-N(CH2-COO)2]K3-xNax (I) où x est compris entre zéro et 2,9.
Patent CA-2966211-A1 (CA)
Inventor: BROWN ERIC
IPC: C07K16/44
Filed: 2015-12-02
Abstract: The invention provides rF1 antibody antibiotic conjugates and methods of using same.
Patent CA-2966567-A1 (CA)
Inventor: SAMBUSSETI ANTONIO
IPC: A61F2/00
Filed: 2015-11-12
Abstract: A device for the reconstruction of the rotator cuff comprises a flat element (2) having at least two opposite ends (2a, 2b) and adapted to be connected to at least one of the damaged tendons of the rotator cuff of a patient at said ends (2a, 2b); said flat element (2) being entirely made of biodegradable and resorbable material.
Patent CA-2967049-A1 (CA)
Inventor: SJOLANDER BO THOMAS
IPC: B24B11/10
Filed: 2015-11-12
Abstract: The present disclosure provides a grinding cup for detachable connection to the output drive shaft of a grinding machine for grinding buttons on drill bits or cutters, said grinding cup having top and bottom surfaces and consisting of a lower grinding section and an upper body section co-axial with said grinding section to form said grinding cup with a centrally disposed recess formed in the bottom surface of the grinding section having the desired profile for the button to be ground; the improvement characterized by said body section having a centrally disposed upright drive section formed on the top surface of the grinding cup, said drive section shaped and sized to both driveably engage within a corresponding recess at end of the output drive shaft of said grinding machine and provide axial and radial support and retaining means for detachably connecting the grinding cup to the output drive shaft of the grinding machine wherein said drive section has a non-circular cross section and is tapered from the top surface of the grinding cup to the free end of the drive section.
Patent CA-2968633-A1 (CA)
Inventor: DING KE
IPC: A61K31/506
Filed: 2015-11-18
Abstract: Disclosed are a 2-aminopyrimidine compound and pharmaceutical composition and use thereof. The structure of the 2-aminopyrimidine compound is as represented by formula I, in the formula, R1, R2, R3, R4, R5, X, Y, Z, W, (i) being as defined in the specification and the claims. Such compounds effectively inhibit the growth of a variety of tumor cells and have inhibitory effects on EGFR and IGF1R protease, and can be used for preparing antineoplastic drugs and overcome the tolerance induced by the existing drugs such as gefitinib, erlotinib and the like. The compound has selectivity for tumors, in particular the wild-type non-small cell lung cancer and have good pharmacokinetic characteristics.
Patent CA-2968891-A1 (CA)
Inventor: MCGUIRE KENNETH STEPHEN
IPC: B65D30/10
Filed: 2015-12-18
Abstract: Non-durable self-supporting flexible containers with easily variable sizing. Line ups of flexible containers have similar sizes, shapes, and constructions, but hold differing amounts of fluent product at unexpected fill heights.
Patent CA-2974713-A1 (CA)
Inventor: DENINA GIOVANNI LAVISTE
IPC: G01N21/00
Filed: 2015-02-26
Abstract: A quality control method or system for determining a lubricant coverage at the inside surface of a syringe barrel is provided. The timing for the quality control is not intuitive, yet crucial for patient's safety. The pre-fill test is for a pre-filled (empty or no drug solution), yet oil lubricated, barrel. This pre-fill test needs to be performed within a certain time window immediately following the lubrication. The post-fill test is for a post-filled oil lubricated syringe barrel filled with a solution. This post-fill test needs to be performed after a certain time window has passed from the filling with the solution. The quality control methods could lead to a reduction of health-risks or avoid life- threatening situations associated with syringes that are either below or above the desired lubrication coverage.
Patent CA-2975124-A1 (CA)
Title: Control of a computer via distortions of facial geometry
Inventor: MOFFAT BRIAN LEE
IPC: G06K9/66
Filed: 2016-02-01
Abstract: A system which, with data provided by one or more sensors, detects a user's alteration of the geometries of parts of his face, head, neck, and/or shoulders. It determines the extent of each alteration and normalizes it with respect to the maximum possible range of each alteration so as to assign to each part-specific alteration a numeric score indicative of its extent. The normalized part-specific scores are combined so as to produce a composite numeric code representative of the complete set of simultaneously-executed geometric alterations. Each composite code is translated, or interpreted, relative to an appropriate context defined by an embodiment, an application executing on an embodiment, or by the user. For example, each composite code might be interpreted as, or assigned to, a specific alphanumeric letter, a color, a musical note, etc.
Patent CA-2979783-A1 (CA)
Inventor: GRIFFITHS ROBERT C
IPC: B64D47/08
Filed: 2017-09-20
Abstract: Une méthode et un appareil pour un système de surveillance daéronefs. Le système de surveillance daéronefs comprend des cibles associées aux ailes de laéronef, un système de caméra et un moniteur. La configuration du système de caméra permet de capter des images des cibles situées sur laile pendant le vol. Le moniteur est configuré de façon quil mesure le mouvement des cibles au moyen des images, ce qui permet de déterminer les mouvements des ailes.
Patent CA-2982775-A1 (CA)
Inventor: FARUKI HAWAZIN
IPC: C12Q1/68
Filed: 2016-04-14
Abstract: Methods and compositions are provided for the molecular subtyping of lung cancer samples. Specifically, a method of assessing whether a patient's adenocarcinoma lung cancer subtype is terminal respiratory unit (TRU), proximal inflammatory (PI), or proximal proliferative (PP) is provided herein. The method entails detecting the levels of the classifier biomarkers of Table 1-Table 6 or a subset thereof at the nucleic acid level, in a lung cancer sample obtained from the patient. Based in part on the levels of the classifier biomarkers, the lung cancer sample is classified as a TRU, PI, or PP sample.
Patent CA-2984503-A1 (CA)
Inventor: WEBER THEODORE E
IPC: H05B39/04
Filed: 2016-04-29
Abstract: This disclosure relates to systems and methods for controlling electrical loads in one or more areas. The system includes a room controller having a microprocessor for accessing data and providing commands, memory for storing information operably connected to the microprocessor, a relay for powering a load based on commands from the microprocessor, and a port for connecting a peripheral device. The system also includes a peripheral device connected to the port and configured to send data to the controller indicating the type of peripheral device; and a load connected to the relay.
Patent CA-2987417-A1 (CA)
Title: Method and apparatus for representing an image with plasmonic pixels
Inventor: JAMES TIMOTHY DENIS
IPC: G02B5/20
Filed: 2016-06-02
Abstract: A plasmonic pixel structure, comprising: a substrate; a plurality of nano-scale structures each comprising conducting and dielectric components, whereby the nano-scale structures are configured to act as nano-antennas. The nano-scale structures 5 have resonant frequencies that depend on the conducting component and sizes of the nano-scale structures. The conducting component and the sizes of the nano-scale structures are selected according to a wavelength component or components of incident light desired to be reflected or transmitted by the nano-scale structures, and the conducting component and the sizes of the nano-scale structures are selected 10 such that the nano-scale structures have respective resonant frequencies corresponding to a colour scheme.
Patent CA-2990061-A1 (CA)
Title: Boron-free glass fiber composition, glass fiber and composite material therefrom
Inventor: ZHANG LIN
IPC: C03C13/02
Filed: 2015-11-12
Abstract: A Boron-free glass fiber composition, and a glass fiber and a composite material therefrom.  The glass fiber composition comprises the following components in percentage by weight: 58%  to 60.4% of SiO2, 14% to 16.5% of A1203, 14.1% to 16.5% of CaO, 6% to 8.2% of MgO, 0.01%  to 0.5% of Li2O, less than 1.15% of Na2O+K20, K20 being higher than 0.5%, less than 1.5% of TiO2, and less than 1% Fe2O3, the ratio in percentage by weight C1=CaO/MgO  being greater than 2 and smaller than or equal to 2.4. The composition can remarkably reduce the surface tension of glass, improve the mechanical strength and the chemical resistance stability of the glass fiber, effectively suppress the crystallization tendency of glass, reduce the liquidus temperature of glass, and is particularly suitable for producing high-performance glass fiber having a low bubble rate.
Patent CA-2990261-A1 (CA)
Inventor: PURNHAGEN HEIKO
IPC: G10L19/08
Filed: 2014-05-23
Abstract: La présente divulgation concerne des procédés, des dispositifs et des produits de programme informatique pour le codage et le décodage dun vecteur de paramètres dans un système de codage audio. La divulgation concerne de plus un procédé et un appareil permettant de reconstruire un objet audio dans un système de décodage audio. Selon la divulgation, une approche utilisant un calcul différentiel modulo pour coder et décoder un vecteur dune quantité non périodique permet daméliorer lefficacité de codage, et dobtenir des codeurs et des décodeurs exigeant moins de mémoire. De plus, la divulgation concerne un procédé efficace de codage et de décodage dune matrice creuse.
Patent CA-2990748-A1 (CA)
Inventor: ASZODI JOSEF
IPC: A61K38/00
Filed: 2016-07-01
Abstract: The invention relates to a new bicyclic lipolantipeptide, representing a new class of lantipeptide, and salts thereof, their preparation from a culture of a Microbacterium arborescens, and their use as antimicrobial agent in the prevention and treatment of infections in humans, animals or plants.
Patent CA-2991326-A1 (CA)
Inventor: GERARD BAUDOUIN
IPC: C07D487/04
Filed: 2016-07-21
Abstract: The invention relates to novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.
Patent CA-2991688-A1 (CA)
Title: Dispositif de regulation de la dose pour dispositifs d'administration de medicament injectable.
Inventor: MARCOZ ALAIN
IPC: G01R33/02
Filed: 2015-07-21
Abstract: La présente invention concerne un dispositif de régulation de la dose conçu pour être monté de manière amovible sur une surface périphérique extérieure d'un dispositif d'administration de médicament injectable, le dispositif d'administration de médicament comprenant un corps d'administration de médicament de forme sensiblement allongée, au moins un médicament injectable maintenu par le corps, le corps ayant une extrémité distale et une extrémité proximale, le dispositif de régulation de la dose comprenant un premier composant conçu de manière à s'adapter et à sensiblement envelopper au moins une partie d'une surface périphérique extérieure du dispositif d'administration de médicament, et situé au niveau d'une extrémité proximale dudit dispositif d'administration de médicament ; un second composant conçu de manière à s'adapter et à sensiblement envelopper une partie non enveloppée restante correspondante de la surface périphérique extérieure dudit dispositif d'administration de médicament, et également situé au niveau d'une extrémité proximale dudit dispositif d'administration de médicament ; ledit premier composant et ledit second composant venant en prise de manière amovible l'un avec l'autre pour former une unité ayant un alésage longitudinal qui s'étend le long d'un axe longitudinal dudit dispositif d'administration de médicament, et dans ledit alésage le dispositif d'administration de médicament étant enveloppé entre ledit premier composant et ledit second composant.
Patent CA-2994089-A1 (CA)
Inventor: CHRISTENSEN SIGNE M
IPC: C12N15/113
Filed: 2003-11-18
Abstract: A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved antisense properties.  The novel oligonucleotides are composed of at least one LNA selected from beta-D-thio/amino-LNA or alpha-L-oxy/thio/amino-LNA. The oligonucleotides comprising LNA may also include DNA and/or RNA nucleotides.
Patent CA-2996572-A1 (CA)
Inventor: LARSON TODD A
IPC: B65G69/18
Filed: 2018-02-27
Abstract: A dust control device for preventing debris from escaping into the atmosphere during loading rail cars with granular products includes a hood that is moveably supported on a pair of stationary elongated support rails via wheels.  The support rails are attached to a delivery spout of an elevator and extend over the path of travel of a rail car to be loaded. An elongated pivotable engagement arm connected to the dust hood extends downwardly into the path of the rail car and is engaged as the car passes beneath the dust hood. The dust hood moves with the rail car from a ready position to an operational position in proximity to the delivery spout to capture the debris. When the rail car disengages from the engagement arm, the dust hood returns to the ready position automatically and without a power source under the force exerted by a spring-biased positioning assembly.
Patent CA-2996969-A1 (CA)
Title: Mobile microscope
Inventor: LUNDIN JOHAN
IPC: G02B21/00
Filed: 2016-08-26
Abstract: The invention relates to a mobile microscopic imaging device comprising a sample stage for holding a sample to be imaged, at least one light source for illumination of the sample, an imaging panel capable of capturing an image of the sample upon transmission illumination of the sample by the light source, and an optical magnification unit between the sample and the imaging panel for guiding light from the illuminated sample to the imaging panel so that a magnified image of at least portion of the sample is formed at the imaging panel. According to the invention, the optical magnification unit comprises a filter integrated polymeric lens assembly in a transmitted light fluorescence configuration which allows for both miniaturization of the device to a truly mobile level and reducing manufacturing costs.
Patent CA-2999538-A1 (CA)
Inventor: MELIGA STEFANO
IPC: A61M37/00
Filed: 2016-09-28
Abstract: An apparatus for delivering an active ingredient into the skin of an animal at a defined depth, the apparatus including: a microprojection array including a plurality of microprojections having a density of at least 2,000 projections per cm2; and an applicator that drives the microprojection array towards the skin in use so that the microprojection array impacts on the skin with a mass-to-velocity ratio of between 0.0005 g/m/s and 0.1 g/m/s per cm2 .
Patent CA-3001152-A1 (CA)
Inventor: HONIGBERG LEE
IPC: A61K31/519
Filed: 2008-03-27
Abstract: Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.
Patent CA-3001203-A1 (CA)
Inventor: DAMMEYER KARL L
IPC: B66F17/00
Filed: 2012-02-13
Abstract: A materials handling vehicle is provided comprising: a support structure including a fixed member; a movable assembly coupled to the support structure; a hydraulic system; and a control system. The support structure further comprises lift apparatus to effect movement of the movable assembly relative to the support structure fixed member. The lift apparatus includes at least one ram/cylinder assembly. The hydraulic system includes a motor, a pump coupled to the motor to supply a pressurized fluid to the at least one ram/cylinder assembly, and at least one electronically controlled valve associated with the at least one ram/cylinder assembly. The control structure may estimate a speed of the movable assembly from a speed of the motor and control the operation of the at least one valve using the estimated movable assembly speed.
Patent CA-3002111-A1 (CA)
Inventor: TOMLINSON PAUL JAMES
IPC: A61Q19/00
Filed: 2016-10-25
Abstract: La technologie selon l'invention concerne une composition comprenant un acide ascorbique O-substitué ou un dérivé de celui-ci; et la gluconolactone, la composition comprenant une phase aqueuse présente jusqu'à 95 % en poids de la composition. L'invention concerne également l'utilisation et un procédé d'amélioration de l'état de la peau
Patent CA-3002624-A1 (CA)
Title: Procede pour augmenter la bioactivite d'extraits d'ashwaganda
Inventor: ANTONY BENNY
IPC: A61K36/81
Filed: 2016-10-18
Abstract: L'invention concerne un extrait d'ashwagandha qui présente une bioactivité et une biodisponibilité renforcées et qui est enrichi en glycosides withanolides et saponines, tout en comprenant une quantité négligeable d'alcaloïdes, d'aglycones withanolides et d'oligosaccharides. L'extrait selon l'invention, préparé à partir de racines, feuilles, tiges et plante entière d'ashwagandha, présente en outre une activité immunomodulatrice, une activité anti-inflammatoire, une activité antistress, une activité antidiabétique et un effet sur la qualité du sommeil améliorés. L'invention concerne également un procédé d'amélioration de la bioactivité de glycosides withanolides, même à des doses inférieures, par l'administration d'une formulation à enrobage gastro-résistant d'extrait d'ashwagandha à des êtres humains. L'enrobage gastro-résistant protège la composition contre l'hydrolyse dans l'environnement acide de l'estomac, pour libérer le glycoside withanolide dans le pH neutre/alcalin du tractus gastro-intestinal, ce qui permet d'améliorer l'absorption. Le procédé de préparation de l'extrait d'ashwagandha enrichi en glycosides withanolides et en saponines est également décrit, conjointement avec diverses formulations.
Patent CA-3002914-A1 (CA)
Title: Acrylic copolymer, which is hydrophobic, cross-linked and based on cinnamic alcohol, for intraocular lenses
Inventor: TERRISSE JEAN
IPC: A61F2/16
Filed: 2016-11-10
Abstract: The material according to the invention is an acrylic copolymer, which is cross-linked, viscoelastic, flexible and deformable at room temperature and hydrophobic, with at least 50 wt % of acrylic or methacrylic monomers and cinnamic alcohol. The mixture of monomers preferably includes: at least one arylalkoxy-acrylate or one arylalkoxy-methacrylate; at least one hydroxylated acrylate and one hydroxylated methacrylate; at least one ethoxylated diol diacrylate and one ethoxylated diol dimethacrylate; and cinnamic alcohol. Said material is obtained in a single step of radical polymerisation and is presented in the form of a three-dimensional macromolecular network including a cinnamic alcohol unit. Said material is used for manufacturing intraocular lenses (1).
Patent CA-3003657-A1 (CA)
Title: Embedded concrete anchor system
Inventor: JABLONSKY DAVID S
IPC: E04B1/41
Filed: 2016-10-28
Abstract: An adjustable location anchor with a greatly increased strength having wide versatility regarding the types of straps or attachments which are usable therewith. The invention includes an extended housing having an interior cavity which includes a main slot and which can include a pair of anterior flanges or wings, wherein the extended housing can be placed into the uncured concrete such that it is rigidly embedded therein upon curing. A sliding insert can then be provided within the interior cavity being configured to slide along a slot formed thereby. The extended housing can also have one or more reinforcement attachment means for connecting to existing concrete reinforcement structures.