baber/WOPTO huggingface dataset:
Patent PT-512260-E (PT)
Inventor: BREY ROBERT NEWTON III
IPC: A61P31/04
Filed: 1992-04-06
Abstract: This invention pertains to a complementation system for the selection and maintenance of expressed genes in bacterial hosts. The invention provides stable vectors which can be selected and maintained by complementation of chromosomal deletion mutations of purA (adenylosuccinate synthetase), obviating the use of antibiotic resistance genes. This system is useful in production organisms during fermentation and in live vaccine bacteria, such as attenuated Salmonella typhi. This system allows for selection of chromosomal integrants and for selection and stable plasmid maintenance in the vaccinated host without application of external selection pressure.
Patent PT-549234-E (PT)
Inventor: CHU SHAW-CHANG
IPC: C08J7/054
Filed: 1992-12-15
Abstract: A thermoplastic film comprising a base layer of a thermoplastic resin which comprises antifogging, heat-sealable polypropylene film wherein the antifog agent is a polyglycerol ester or sorbitan ester of fatty acids. The resultant film, which has good clarity, persistent antifogging characteristics, and excellent heat sealability, is useful for packaging refrigerated foods. The disclosure also provides a process for making the film in which the polypropylene-containing thermoplastic resin is extruded into a sheet, said sheet oriented in the longitudinal direction to form a monoaxially oriented film, said film containing said polyglycerol ester or sorbitan ester of fatty acids and orienting said film in the transverse direction.
Patent PT-649371-E (PT)
Inventor: KING MICHAEL J
IPC: B29C41/04
Filed: 1993-06-21
Abstract: A tire recapping and retreading method and apparatus that includes a rigid, segmented tread mold. The mold is retained in place over the tire carcass and uncured tread material by a resilient elastic tension band or prestressed metal tension springs. Further retaining force is provided by a resilient envelope to complete the formation of the retread when the tire and apparatus is placed in a hot air oven. The use of the rigid segmented mold described eliminates the distortion of the tire carcass by the mold.
Patent PT-711546-E (PT)
Inventor: CABRERA ANTONIO LOPEZ
IPC: A61K9/00
Filed: 1994-09-07
Abstract: The ophtalmic solution comprises (a) the equivalent to 0.001-0,14 % of Diclofenac itself or an isomer, or a derivative or one of the pharmaceuticaly acceptable salts thereof; (b) the equivalent to a value of 0.001-0.45 % of Tobramicine, obtained from Tobramicine itself or from an isomer or a derivative or one of its pharmaceutically acceptable salts thereof; (c) optionally a solubilizer, an isotonizer, a pH damper, a viscosizer, a chelator, a preserving agent, and/or an excipient for pharmaceutical hydrogels. Application to the treatment of ocular and otic inflammations and/or infections.
Patent PT-792268-E (PT)
Inventor: BRIEADDY LAWRENCE EDWARD
IPC: C07F9/6536
Filed: 1995-11-16
Abstract: PCT No. PCT/GB95/02700 Sec. 371 Date May 1, 1997 Sec. 102(e) Date May 1, 1997 PCT Filed Nov. 16, 1995 PCT Pub. No. WO96/16051 PCT Pub. Date May 30, 1996The invention is concerned with novel hypolipidemic compounds of formula (I), with processes and novel intermediates for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, and associated diseases such as atherosclerosis.
Patent PT-934276-E (PT)
Inventor: ASHWORTH PHILIP ANTHONY
IPC: C07D401/12
Filed: 1997-10-17
Abstract: Anthranilic acids of formula (I):wherein each of R to R9 is an organic substituent, n is 0 or 1, m is 0 or an integer of 1 to 6, q is 0 or 1, X is a direct bond, O, S, -S-(CH2)p or -O-(CHO2)p- wherein p is from 1 to 6 and Ar is an unsaturated carbocyclic or heterocyclic group, and the pharmaceutically acceptable salts thereof, have activity as inhibitors of P-glycoprotein and may thus be used, inter alia, as modulators of multidrug resistance in the treatment of multidrug resistant cancers, for example to potentiate the cytotoxicity of a cancer drug.
Patent PT-863155-E (PT)
Inventor: WEINER HOWARD L
IPC: A61K38/095
Filed: 1993-04-09
Abstract: Peptides derived from fragment 84-102 of hMBP by deleting one to four N-terminal amino acids and/or one to eight C-terminal amino acids and containing an alanine residue at position 85,86,87,88,89,90,91,92,93,94,95,96,97,98, or 99.These peptides are useful to suppress autoimmune responses.
Patent PT-998480-E (PT)
Inventor: ROHLOFF JOHN C
IPC: C07D473/34
Filed: 1998-07-23
Abstract: The invention provides a composition comprising bis(POC)PMPA and fumaric acid (1:1). The composition is useful as an intermediate for the preparation of antiviral compounds, or is useful for administration to patients for antiviral therapy or prophylaxis. The composition is particularly useful when administered orally. The invention also provides methods to make PMPA and intermediates in PMPA synthesis. Embodiments include lithium t-butoxide, 9-(2-hydroxypropyl) adenine and diethyl p-toluenesulfonylmethoxy-phosphonate in an organic solvent such as DMF. The reaction results in diethyl PMPA preparations containing an improved by-product profile compared to diethyl PMPA made by prior methods.
Patent PT-983904-E (PT)
Inventor: MARCUS ARMIN
IPC: B62D31/02
Filed: 1999-07-08
Abstract: For the mounting of windows in buses and similar passenger transportation vehicles, a set of profiled strips is provided, the set comprising a uniform base profile (5), a covering profile (6) and a uniform adaptor profile (7) for supporting a cover (20). The base profile (5) is designed in such a manner that it fits against horizontally and vertically aligned struts (1, 2) of a window wall, optionally after prior trimming. The base profile, which has an approximately L-shaped cross section, is provided with a groove (12) which serves as a clip holder and into which a clip web (17) on the covering profile (6) or a clip web (19) on the adaptor profile (7) can be clipped. The profiles (5, 6 and 7) consist in each case of sections of extruded profiled strips which have been cut to size.
Patent PT-1097173-E (PT)
Title: The use of peptides of il-2 and derivatives thereof as therapeutic agents
Inventor: THEZE JACQUES
IPC: C07K16/24
Filed: 1999-07-16
Abstract: The present invention relates to new peptides of IL-2, derivatives thereof, and their use as therapeutic agents.
Patent PT-1123341-E (PT)
Inventor: MOLINA NELSON F
IPC: C08G18/65
Filed: 1999-09-03
Abstract: Mannich polyols having a viscosity of from 300 to 3,500 cps (0.3 to 3.5 Pa*s) at 25° C. are prepared by admixing a phenol, an alkanolamines, and formaldehyde mixed in molar ratios of from 1:1:1 to 1:2.2:2.2 resulting in an initiator which can be alkoxylated using a mixture of ethylene oxide and propylene oxide to prepare polyols that have a nominal functionality of from 3 to 5.4.
Patent CA-2448699-F (CA)
Title: Bag filling apparatus and method
Inventor: DROOG THOMAS W
IPC: B65B43/36
Filed: 1999-02-15
Granted: 2000-08-15
Abstract: Automated apparatus for filling of a bag with a loose commodity comprises a bag filling station for dispensing commodity into a bag; a wicket for feeding a stacked and interconnected array of empty bags; and a conveyor for removing filled bags from the filling station. Reciprocating clamps grip the open mouths of the filled bags, and transfer the filled bags away from the filling station, with a subsequent bag being drawn into appropriate position for filling by means of the connection formed between the contacting bags.
Patent SG-47592-G (SG)
Title: Gel-like emulsion and o/w emulsions obtained from the gel-like emulsion
IPC: A61K9/10
Filed: 1992-04-29
Abstract: A gel-like emulsion is prepared by adding an oil to a surfactant continuous phase formed of a monoalkyl phosphate salt, polyhydric alcohol and water. The gel-like emulsion is scarcely dependent on temperature, and a fine and uniform O/W emulsion prepared from the gel-like emulsion reveals excellent stability at the time of production and at storage. The gel-like emulsion contains only a small amount of alkyl phosphate surface active agent of low irritativeness, so that it is usable for cosmetics, pharmaceuticals, industrial products and the like, which are required to have low irritation and high safety.
Patent IE-880101-L (IE)
Title: Process for flavouring foodstuffs
IPC: C12H1/00
Filed: 1988-01-14
Abstract: A process for the flavouring, by yeast treatment, of foodstuffs especially based on vegetable raw materials having little or no flavour, or of compositions based on such materials, in which the said foodstuffs are treated with a yeast culture or an acellular extract of the said yeasts, these yeasts displaying a low esterase activity. It also relates to foodstuffs obtained via this process. <IMAGE>
Patent IE-38769-L (IE)
Title: Pyridine derivatives
IPC: C07D213/65
Filed: 1974-01-18
Abstract: The novel title cpds. of formula (I) (where A and B together represent a C-C bond or an oxygen bridge; or A is H and B is lower alkyl, lower alkoxy or OH; R and R1 are CH3 or C2H5; R2 is H or >=1 substituent on the pyridine ring; and X is O or NH), control insects at doses as low as 10-6-10-9g, and may be prepd. by reacting (II) with (III) or (IV).
[IT1053529B]
Patent IE-780128-L (IE)
Title: Substituted n-acyl phenylamine compounds
IPC: C07C239/00
Filed: 1978-01-20
Abstract: Compounds having hypolipidaemic activity which are substituted aralkylanilines, their preparation and pharmaceutical compositions containing them.
[US4271188A]
Patent IE-800338-L (IE)
Title: Penem compounds
IPC: C07D205/09
Filed: 1980-02-20
Abstract: There are provided penem- carboxylic acids and esters of the general formula <IMAGE> In the formula, n=0 or 1; R''=H, lower alkyl, CCl3CH2-, p.nitrobenzyl, p.methoxybenzyl, phenyl, p.nitrophenyl or benzhydryl or a residue known to undergo metabolic activation in vivo and having favourable pharmacokinetic properties; Z=H, halogen, OH, NH2, NH2COO, SH or pyridinium or OR1, OCOR1, NHCOR1 or SR1 wherein R1=lower alkyl, aryl or a heterocyclic ring, each of which may be substituted or unsubstituted; R'=H, lower alkyl, lower alkoxy cycloalkyl or hydroxyalkyl (the hydroxy group of which is free or protected). Pharmaceutically acceptable salts of these compounds, which are antibacterial agents and beta -lactamase inhibitors, are included in the invention, as is a process for their preparation from penicillanic acid S-oxide esters.
[GB2043639A]
Patent IE-860411-L (IE)
Title: N, n - disubstituted aminoacidamides
IPC: C07C323/52
Filed: 1986-02-14
Abstract: The present invention relates to anticonvulsant compounds useful in the treatment of epilepsy and other central nervous system disorders. The compounds of this invention have the following general formula: <CHEM>  wherein R and R1, independently, are lower alkyl, aryl lower alkyl or phenyl, unsubstituted or substituted with at least one substituent; R2 and R3, independently, are hydrogen, lower alkyl, aryl lower alkyl or phenyl, unsubstituted or substituted with at least one substituent; and  n is 1 to 4. The present compounds can be employed for preparing compositions to be used as anticonvulsant pharmaceuticals.
Patent IE-33380-L (IE)
Title: Cheese making
IPC: A23C19/082
Filed: 1969-06-30
Abstract: 1,251,654. Cheese UNILEVER Ltd. 3 July, 1969 [4 July, 1968], No. 32013/68. Heading A2B. A process for preparing cheese comprises the steps of incubating milk (e.g. pasteurised cows' or buffaloes' milk) with a bacterial cheese starter culture for at least one hour and with a culture containing yeast Candida lipolytica cells for at least 12 hours and contacting the cultured milk with a milk clotting protease (e.g. rennet) to form a flavoured curd. The cheese starter culture or the Candida lipolytica cells culture may be added first to the milk or the two cultures may be added together. The cheese starter culture may be an Emmental or Cheddar cheese starter, the former e.g. comprising lactobacilli and streptococci cells. The flavoured curd may be mixed with a bland curd and a melting salt composition before or during a melting step in the making of a processed cheese. The melting salt composition may comprise sodium chloride and citrate, monosodium glutamate and citric and sorbic acids.
[GB1251654A]
Patent FI-823227-L (FI)
Inventor: BREWER DONALDEE
IPC: B29C33/02
Filed: 1982-09-20
Abstract: The present invention covers the method and apparatus to retread tire casings using a precured tread system where an envelope or flexible fluid type member is used to cover a retread tire casing assembly and then placed in an autoclave where the autoclave is pressurized and a reduced differential pressure is provided between the envelope member and the precured tread. This invention includes the automatic pressurizing of the system and the monitoring of the system during operation as a total system and/or four individual curing stations.
Patent FI-830454-L (FI)
Inventor: SARJA ASKO
IPC: B28B5/02
Filed: 1983-02-09
Abstract: Method and equipment for compacting of concrete mix when concrete products are being cast by means of a continuous method. The concrete mix is carried from the feeder device (4) forwards by means of an endless transfer unit. The compression required for the compacting of the concrete mix is produced by means of a roll (1) pressed against the transfer face (2). The compression is directed at the concrete mix by the intermediate of rigid plates (2) of a caterpillar band constituting the transfer unit, which plates are pressed against the concrete mix by means of two or more support rolls (1).
Patent IE-811159-L (IE)
Title: Laminating process
IPC: G03F7/16
Filed: 1981-05-25
Abstract: In a process for laminating a supported photosensitive layer to a substrate surface by means of pressure, the improvement comprising the sequential steps of: (a) forming a thin layer of liquid on the substrate surface immediately prior to lamination by contacting the suface at a temperature below the condensation point of the liquid with a vapor or gaseous dispersion of the liquid, which layer forms an interface between the substrate surface and the photosensitive layer upon lamination; and (b) displacing the thin layer of liquid from the substrate surface by absorption into the photosensitive layer during lamination.
Patent IE-801444-L (IE)
Title: Tallysomycin derivatives
IPC: C07H15/26
Filed: 1980-07-11
Abstract: Addition of certain amine precursor compounds to the culture medium during fermentation of a tallysomycin-producing strain of Streptoalloteichus hindustanus results in production of new tallysomycin derivatives having advantageous antimicrobial and antitumor properties.
[US4246400A]
Patent IE-861794-L (IE)
Title: Process for producing concentrated solutions of ammonium¹nitrate
IPC: C01C1/18
Filed: 1986-07-03
Abstract: Process for producing concentrated solutions of ammonium nitrate by neutralization of nitric acid with ammonia in a pipe reactor. When the global flow of reactives corresponds to an output higher than 150 kg/h/cm2 neutralization is performed in the presence of recycled concentrated solutions of ammonium nitrate. When the global flow is higher than 150 kg/h/cm2 recycling is not necessary.
[US4927617A]
Patent IE-881799-L (IE)
Title: Monoclonal antibody specific to hiv antigens
IPC: C12N15/02
Filed: 1988-06-14
Abstract: A hybrid cell line is provided which is capable of producing monoclonal antibodies which bind to HIV core antigen P55, the precursor protein coded for the gag gene, the core protein P24 and partial breakdown products P39 and P33. The monoclonal antibody embodying the invention does not bind the P18 core protein or any HIV envelope antigens. The cell line of the invention was developed by a unique immunization protocol in which BALB/c mice were immunized over a series of multiple infusions using a select group of immunogens and a conventional myeloma cell line for fusion with the murine splenocytes harvested. The monoclonal antibody is identified as the KC-57 antibody. This monoclonal antibody is especially useful for a solid phase immunoassay in which the monoclonal antibody is detected in its binding to HIV antigens found in a serum or plasma sample from a human patient. The cell line which produces the KC-57 monoclonal antibody has been deposited in the American Type Culture Collection, Rockville, Md. and assigned A.T.C.C. No. HB 9585.
[US4888290A]
Patent IE-40243-L (IE)
Title: Imidazolyl derivatives
IPC: C07D521/00
Filed: 1974-10-04
Abstract: 1-(IMIDAZOLYL-1')-2-ARYLOXY-3-HYDROXY-ALKANES OF THE FORMULA OH ¦ R1O-CH-C-R3 (I) ¦¦ CH2R2 ¦ in which R1 is optionally substituted aryl, R2 is hydrogen, alkyl, cycloalkyl, alkenyl, optionally substituted aryl or optionally substituted aralkyl, and R3 is alkyl or cycloalkyl, or can be hydrogen if R2 is not hydrogen, AND THEIR SALTS, WHICH POSSESS FUNGICIDAL PROPERTIES.
[US3940415A]
Patent IE-812306-L (IE)
Title: Tasi system
IPC: H04J3/12
Filed: 1981-10-02
Abstract: One of the transmission facilities of a TASI system is used as an order wire, via which channel signalling information and assignment information are transmitted. Signalling information is transmitted periodically in frames on the order wire for only some of the channels, connected to the system, at any one time. Accordingly, the assignment information consists of both channel-to-facility assignment information, relating to the assignment of channels to the other facilities, and channel signalling assignment information, relating to the assignment of channels to signalling bit time channels in the frames on the order wire. One assignment can be transmitted in each frame, and frames not used for transmitting assignment information can be used for transmitting commands and messages. The system avoids the need to transmit multi-tone signals preceding speech bursts on the transmission facilities and avoids lengthy delays in the transmission of channel signalling information.
[US4627049A]
Patent IE-802318-L (IE)
Title: Surface abrasion treatment
IPC: D06C11/00
Filed: 1980-11-07
Abstract: A process is provided for mechanically surface-finishing a textile fabric which comprises ccontinuously feeding said fabric from a source of supply, such that said fabric lies in a single plane, subjecting successive adjacent sections of the fabric to intermittent mechanical impact with an abrasive means across the width of said fabric thereby avoiding substantial sustained contact between the fabric and the abrasive means, the mechanical impact being at a force and frequency sufficient to cause a substantially uniform modification of the surface characteristics of the fabric. Textile fabrics with modified surface which may be made by the above process are also provided. Apparatus for mechanically surface-finishing a textile fabric according to the aforedescribed process is further provided.
[US4316928A]
Patent IE-42105-L (IE)
Title: Stabilised copolyether-esters
IPC: C08L67/00
Filed: 1975-11-17
Abstract: 1519030 Stabilized copolyetheresters BASF AG 14 Nov 1975 [20 Nov 1974] 47022/75 Heading C3R A composition comprises a copolyetherester (P) and a stabilizer (I) where R is C8-10 alkyl; where (P) comprises (a) ester units derivable from a dicarboxylic acid and a polyether glycol, polyalkaline oxide of MW 400-4000, and (b) ester units derivable from a dicarboxylic acid and a diol of MW <280. In Ex. 3, (P) is made by reacting dimethylterephthalate, butane-1,4-diol, polytetrahydrofuran of MW 2000, and Bu4 orthotitanate. There may be 0À05-10% wt. (I) based on (P). Conventional additives may be present. (From GB1519030 A) [FR2292014A1]
Patent IE-832957-L (IE)
Title: Addition of vitamin k to ingestible compositions or¹toothpastes.
IPC: A23L33/15
Filed: 1983-12-15
Abstract: Foodstuffs, chewing gum, tooth paste and pharmaceutical preparations having anti-caries activity, containing at least one vitamin K (including compounds chemically related with vitamin K) as anti-caries agent. Foodstuffs, chewing gum, tooth paste and pharmaceutical preparations having anti-caries activity, containing a combination of at least one vitamin K (including compounds chemically related with vitamin K) on the one hand, and on or more fluorine compounds on the other hand, as anti-caries agent. Milk or a product derived from one or more milk constituents, such as cheese, as a possible basis of the said foodstuffs. Processes for preparing the said products.
Patent NO-812451-L (NO)
Title: Vindrotor.
Inventor: JOUTSINIEMI RISTO T
IPC: F03D5/00
Filed: 1981-07-16
Abstract: Vindskruen er en vindrotor som utpreger seg ved at den roterer både når rotoraksen står vinkelrett på vinden (fig.1 og 2) og når den ligger i vindretningen (fig.3 og 4). Den fungerer med uendret effekt også i alle stillinger mellom vertikalstillingen (fig. 1 og 2) og horisontalstillingen (fig. 3 og 4) og vender alltid samme flater mot vinden uav-hengig av stillingen for rotoraksen (B). Rotorvingene har en noe kupolformet overflate (fig. 1 og 3). Disse faktorer har løst vanskelighetene med å gjøre en og sammen rotor effektiv både i lave vindhastigheter (fig. 1 og 2) og i storm (fig. 3 og 4). Rotoren består av to vinger som er vridd 180° skrueformet om deres rotasjonsakse (fig. 2) og hvis tverrsnitt utgjøres av to halvsirkler (fig. 4 - XX). Rotoren har ikke endeplater, slik at det er mulig for.luften å passere gjennom den'fra dens ene ende (fig. 4), idet rotoren når den befinner seg i horisontalstilling vender mot vinden med bare en sirkelformet flate (fig. 4).Til rotoren hører også et fundament (C,D) som muliggjør at den roterer vertikalt (fig. 1 og 2), horisontalt (fig. 3. og 4) og i alle stillinger derimellom, samtidig som den følger vindretningen.
Patent NO-822830-L (NO)
Inventor: MAASS GUENTHER
IPC: C08L83/06
Filed: 1982-08-19
Abstract: In a plastic organosiloxane molding composition which in the absence of water is capable of being stored and in the presence of moisture is cross-linked to a rubber, the composition comprising a hydroxypolydiorganosiloxane, a nitrogen base and heavy metal compound as cross-linking catalyst, and a cross-linking agent, the improvement which comprises employing as the cross-linking agent a compound of the formula   <IMAGE>   or a partial hydrolysis product thereof, wherein R is an optionally substituted alkyl, alkenyl or aryl group, R1 is hydrogen or R, R2 is an acyl, carbalkoxy or carbaroxy group or R1, a is 1-3, and n is 0, 1 or 2 and a+n</=3.
Patent NO-830934-L (NO)
Inventor: WIDRA ABE
IPC: C08B37/08
Filed: 1983-03-16
Abstract: Hydrophilic biopolymeric copolyelectrolytes are prepared from (a) a water-soluble linear anionic protein polyelectrolyte component derived from keratin, such as ammonium keratinate, and (b) a water-soluble linear cationic biopolymer polyelectrolyte component derived from a glucosaminoglycan and/or collagen, such as chitosan acetate and/or collagen acetate. Hydrogel membranes formed from the copolyelectrolytes are useful as biodegradable dressings for burn wounds and other denuded tissue wound sites.
Patent NO-832875-L (NO)
Inventor: AGAPIOU AGAPIOS
IPC: C08F10/00
Filed: 1983-08-10
Abstract: A method of producing a polymerization catalyst component suitable for use in the polymerization of alpha-olefins, which method comprises forming an active component by co-comminuting an inorganic Lewis acid, a first organic electron donor, a support base selected from the group consisting of the Group IIA & IIIA salts and the salts of the multivalent metals of the first transition series with the exception of copper, and a polymerization active tri-, tetra-, or pentavalent transition metal compound of a Group IVB-VIB metal, and heating the active component in an inert hydrocarbon solvent to produce the polymerization catalyst component. The active component can be heated in the inert hydrocarbon solvent in the presence of an additional polymerization active tri-, tetra-, or penta- valent transition metal compound of a group IVB-VIB metal. In addition, a second organic electron donor may be incorporated in the active component.