baber/WOPTO huggingface dataset:
Patent MX-2017003476-A (MX)
Title: Cytotoxic and anti-mitotic compounds, and methods of using the same.
Inventor: STUART DANIEL BARNSCHER
IPC: A61K47/50
Filed: 2015-09-17
Abstract: Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
Patent MX-2017004630-A (MX)
Title: Methods for conducting stimulus-response studies with induced pluripotent stem cells derived from perinatal cells or tissues.
Inventor: KEVIN P COYNE
IPC: A01N63/00
Filed: 2015-10-15
Abstract: Methods are provided herein for conducting stimulus-response studies on iPSCs, or cells derived from iPSCs, that have been derived from perinatal cells collected from donors under null-exposome conditions. In some embodiments, multiple donors are involved. In other embodiments, the iPSCs are differentiated. The use of induced pluripotent stem cells (iPSCs) derived from cells that originate from neonates enable a scientist to largely remove the influences of age and environmental exposures, allowing a more targeted analysis of the direct interaction between a stimulus and a test subject. Furthermore, use of iPSCs derived from cells originating from multiple donors enable the scientist to obtain more precise measurements of the role of genetic differences in determining responses to a given stimulus than the use of other test materials, by eliminating the vast majority of the differential influences of age and environment among test subjects.
Patent MX-2017006173-A (MX)
Title: Active vehicle interior trim panel with accordion fold.
Inventor: S M ISKANDER FAROOQ
IPC: B60J5/08
Filed: 2017-05-11
Abstract: An active trim panel is for covering at least a portion of a pillar in a vehicle interior. The panel may include a body for covering the portion of the pillar. The body includes at least one accordion fold for expanding from a first position with the body closer to the pillar to a second position with the body spaced from the pillar as a result of the expansion of the accordion fold.
Patent MX-2017006769-A (MX)
Title: Antiglare touch screen displays and other coated articles and methods of forming them.
Inventor: SONGWEI LU
IPC: C08G77/02
Filed: 2015-11-25
Abstract: Touch screen displays and other coated articles demonstrating antiglare properties are provided. A method of forming an antiglare coating on a substrate is also provided, and may be used to prepare the coated articles. The method comprises: (a) heating the substrate to a temperature of at least 100 F (37.8 C) to form a heated substrate; (b) applying a curable film-forming composition on at least one surface of the heated substrate to form a substrate coated with a sol-gel layer; and (c) subjecting the coated substrate to thermal conditions for a time sufficient to effect cure of the sol-gel layer. The curable film-forming composition comprises: (i) a silane; (ii) a mineral acid; and (iii) a solvent; wherein the weight ratio of mineral acid to silane is greater than 0.008:1 and the curable film-forming composition has a solids content of less than 10 percent by weight.
Patent MX-2017007068-A (MX)
Title: Grabber for a front loader refuse vehicle.
Inventor: HENRY MICHAEL HUND JR
IPC: B65F3/04
Filed: 2017-06-05
Abstract: A grabber assembly has a beam assembly with a bracket. A grabber gear assembly is coupled with the bracket. The grabber gear assembly has a pair of gear mechanisms coupled with the bracket. Each gear mechanism has a shaft and a pair of thrust bearings, one at each end of the shaft. A grabber arm mounting pad is coupled with each shaft. A gear section is coupled with each shaft. The gear sections of each shaft mesh with one another to drive the grabber arm mounting pads. An actuating driver is coupled with one of the shafts to drive the grabber gear assembly and move the arms between an open and grasping position.
Patent MX-2017007122-A (MX)
Title: Low haze polyethylene polymer compositions.
Inventor: MEHMET DEMIRORS
IPC: C08L23/06
Filed: 2015-10-23
Abstract: Embodiments of a polyethylene polymer blend having a melt index (l2) < 2 g/10 min are provided, wherein the polyethylene polymer blend comprises at least about 50% by wt. of at least one high density polyethylene resin (HDPE) having a density > 0.950 g/cm3, a melt index (l2) < 4 g/10 min; a melt flow ratio (I10/I2) = 9, and a molecular weight distribution (MWD) of about 2 to about 5; and further comprises about 1% to about 20% by wt. of at least one low density polyethylene resin (LDPE) having a density < 0.930 g/cm3, a melt index (l2) of about 0.1 to about 10 g/min, and an MWD > 3.
Patent MX-2017008004-A (MX)
Title: Cpvc pipe fitting having improved resistance to environmental stress cracking.
Inventor: MARK D JULIUS
IPC: F16L9/12
Filed: 2015-12-17
Abstract: The disclosed technology relates to a plastic compound suitable for preparing articles, such as pipe fittings and valves, with good physical properties, such as impact strength, and resistance to environmental stress cracking (ESC). In particular, the technology relates to a vinyl chloride resin, which includes chlorinated polyvinyl chloride ("CPVC") homopolymer. Furthermore, the invention relates to vinyl chloride homopolymer compounds containing the vinyl chloride homopolymer resin, and articles made from such compounds, which compounds meet 23447 cell classifications under ASTM D1784.
Patent MX-2017008916-A (MX)
Title: Systems and methods for visualizing structural variation and phasing information.
Inventor: MICHAEL SCHNALL-LEVIN
IPC: G16B45/00
Filed: 2016-01-13
Abstract: A system for providing structural variation or phasing information is provided. The system accesses a nucleic acid sequence dataset corresponding to a target nucleic acid in a sample. The dataset comprises a header, synopsis, and data section. The data section comprises a plurality of sequencing reads. Each sequencing read comprises a first portion corresponding to a subset of the target nucleic acid and a second portion that encodes an identifier for the sequencing read from a plurality of identifiers. One or more programs in the memory of the system use a microprocessor of the system to provide a haplotype visualization tool that receives a request for structural variation or phasing information from the dataset. The request is evaluated against the synopsis thereby identifying portions of the data section. Structural variation or phasing information is formatted for display in the haplotype visualization tool using the identified portions of the data section.
Patent MX-2017010755-A (MX)
Title: Glazing comprising a protective coating.
Inventor: STÉPHANE LAURENT
IPC: C03C17/36
Filed: 2016-02-23
Abstract: The invention relates to a material comprising a transparent substrate coated with a stack of thin layers comprising at least one silver-based functional layer, characterized in that the stack comprises a protective coating deposited on top of at least one portion of the functional layer, the protective coating comprising: - a lower protective layer having a thickness of between 1 and 10 nm, - a central protective layer based on graphite carbon located on top of the lower protective layer, and - an upper protective layer having a thickness of between 1 and 10 nm located on top of the central protective layer.
Patent MX-2017012295-A (MX)
Title: Formylated n-heterocyclic derivatives as fgfr4 inhibitors.
Inventor: PASCAL FURET
IPC: C07D401/14
Filed: 2016-03-23
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.
Patent MX-2017013034-A (MX)
Title: Continuous beamforming while moving: method to reduce spatial aliasing in leak detection.
Inventor: YI YANG ANG
IPC: E21B47/00
Filed: 2016-05-11
Abstract: Tools, systems, and methods may be configured for or include detecting one or more underground acoustic sources and localizing them in depth and radial distance from a wellbore using an array of at least three acoustic sensors disposed in the wellbore in conjunction with array-signal-processing that accounts for movement of the acoustic sensors and spatial aliasing by using adaptive time dependent modelled steering vector weights.
Patent MX-2017013038-A (MX)
Title: Adjustable low gloss powder coating compositions.
Inventor: THOMAS STEVENSON
IPC: C09D5/03
Filed: 2016-04-08
Abstract: Thermosetting powdered coating compositions comprising (a) a high Acid Value carboxylic acid functional polyester resin having an Acid Value of at least 100 mg KOH/g and a functionality of at least 4.5, (b) a low Acid Value carboxylic acid functional polyester resin having an Acid Value of 20 to 50 mg KOH/g and a functionality of about 2.5 or less, and (c) a cross-linking agent. The high Acid Value polyester resin is the reaction product of a polycarboxylic acid or its anhydride reacted with a polyester polyol obtained from reacting 0 mol percent to 100 mol percent of isophthalic acid and/or 0 to 100 mol percent terephthalic acid, or a mixture thereof, with a polyol mixture comprising at least one dial and at least one polyol having at least three hydroxyl groups. The thermosetting powdered coating compositions provide coatings with low gloss levels that can be adjusted from a gloss level of less than 1 to 40 or less, when measured at an angle of 60 degrees.
Patent MX-2017013563-A (MX)
Title: Selective androgen receptor degrader (sard) ligands and methods of use thereof.
Inventor: DUANE D MILLER
IPC: C07C271/02
Filed: 2016-04-21
Abstract: This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.
Patent MX-2017016002-A (MX)
Title: Enhanced engine and battery operation.
Inventor: WILLIAM PAUL PERKINS
IPC: G08G1/0969
Filed: 2017-12-08
Abstract: Information of a plurality of locations on a route for a vehicle is received. A plurality of segments of the route is identified based at least in part on the information. A specified state of charge of a vehicle battery and a specified power output of an engine are determined for each of the segments based at least in part on the information. One or more vehicle subsystems is actuated to navigate each of the segments to change a current state of charge of the vehicle battery to the specified state of charge.
Patent MX-2017017120-A (MX)
Title: Additive for hydraulically setting compositions.
Inventor: HARALD GRASSL
IPC: C04B40/00
Filed: 2016-06-27
Abstract: The present invention relates to an additive for hydraulically setting compositions comprising a colloidally disperse preparation comprising at least one salt of a polyvalent metal cation with at least one organic phosphonate and/or phosphate compound as anion and at least one polymeric dispersant comprising anionic and/or anionogenic groups and polyether side chains. The additive is especially suitable as slump retainer and for improving early strength.
Patent MX-2018000495-A (MX)
Title: Driving plan device, travel support device, and driving plan method.
Inventor: SUSUMU FUJITA
IPC: G08G1/16
Filed: 2015-07-21
Abstract: The present invention comprises a driving plan processor 21 that drafts a driving plan for a vehicle V1 traveling a path. The present invention determines one action for each of a plurality of events that the vehicle V1 encounters chronologically during travel along a first path, uses the details for each action determined for each event, and drafts a series of driving plans for scenes encountered by the vehicle V1.
Patent MX-2018000637-A (MX)
Title: Nanocapsule for delivery of lipophilic compound and process of preparation thereof.
Inventor: Szczepan ZAPOTOCZNY
IPC: A61K9/10
Filed: 2016-07-12
Abstract: The invention relates to biocompatible polysaccharide-based nanocapsule templated on oil core of diameter not exceeding 1 µ, stabilized without low molecular weight surfactants. The nanocapsule shows long-term stability in an aqueous suspension and is able to highly efficient encapsulation of hydrophobic compounds.
Patent MX-2018002668-A (MX)
Title: Wearable in-vehicle eye gaze detection.
Inventor: DEVINDER SINGH KOCHHAR
IPC: B60K28/00
Filed: 2015-09-21
Abstract: A system, including: one or more sensors included in an apparatus wearable by a vehicle operator to measure ocular muscle movement; and a computer that includes a processor and a memory, the memory storing instructions executable by the computer such that the computer is programmed to: receive data indicating ocular muscle movement from the wearable sensor; determine, using the measurement, a gaze direction of the operator; use the gaze direction to determine a level of operator attentiveness; and actuate a vehicle operation if the level of operator attentiveness is below a predetermined threshold.
Patent MX-2018002785-A (MX)
Title: Printed circuit board power cell with isolation and medium voltage multi-cell power supply.
Inventor: EDWARD A NOVACK
IPC: H02M7/483
Filed: 2016-09-09
Abstract: A printed circuit board (PCB) power cell (100) for arranging in a multi-cell power supply (500) includes a housing assembly (102) with a multiple section housing (104, 106), and a PCB assembly (120) positioned within the housing assembly (102), wherein the housing assembly (102) and the PCB assembly (120) are configured to provide an integrated voltage isolation of the power cell (100) which supports an output voltage of the multi-cell power supply (500). Furthermore, a multi-cell power supply (500) including a PCB power cell (100) with isolation is described.
Patent MX-2018004640-A (MX)
Title: Soft tissue grafts, and methods of making and using same.
Inventor: JINGSONG CHEN
IPC: A61F2/02
Filed: 2016-10-14
Abstract: Soft tissue grafts, packaged soft tissue grafts, and methods of making and using soft tissue grafts are disclosed. One soft tissue graft includes processed tissue material having first and second opposed surfaces. The first and second opposed surfaces are bounded by first and second edges. The first edge has a concave shape that curves toward the second edge. The second edge has a convex shape that curves away from the first edge. The first surface comprises a plurality of apertures. At least one of the apertures is formed from a multi-directional separation in the first surface. One method of making a soft tissue graft includes positioning a cutting die on a surface of tissue material, pressing the cutting die into the tissue material to cut the tissue material, and processing the cut tissue material to create processed tissue material.
Patent MX-2018011039-A (MX)
Title: Podocalyxin and tra-related antibody, methods of preparation and uses as an anti-cancer therapeutic agent.
Inventor: William Michael SCHOPPERLE
IPC: C12Q1/68
Filed: 2017-03-13
Abstract: The invention relates to an antibody or an antigen-binding fragment thereof, including a heavy chain and a light chain, with heavy chain complementarity determining regions 1 to 3 having the amino acid sequences of SEQ ID NOS. 1 to 3, respectively, and light chain complementarity determining regions 1 to 3 having the amino acid sequences of SEQ ID NOS. 4 to 6, respectively. In addition, the invention relates to an anti-cancer therapeutic agent including the antibody or the antigen-binding fragment thereof.
Patent MX-2018011536-A (MX)
Title: Compositions and methods for use of eflornithine and derivatives and analogs thereof to treat cancers, including gliomas.
Inventor: VICTOR A LEVIN
IPC: A61K31/195
Filed: 2017-03-16
Abstract: Eflornithine is an agent that can be used to treat glioma, especially glioma of WHO Grade II or Grade III such as anaplastic glioma. Eflornithine can suppress or prevent mutations in glioma which can cause the glioma to progress to a higher grade. Compositions and methods can include eflornithine or a derivative or analog of eflornithine, together with other agents such as conventional anti-neoplastic agents for treatment of glioma, inhibitors of polyamine transport, polyamine analogs, or S- adenosylmethionine decarboxylase inhibitors.
Patent MX-2018011581-A (MX)
Title: Herbicide tolerant protein, encoding gene and use thereof.
Inventor: QING TAO
IPC: C12N9/14
Filed: 2016-12-09
Abstract: A herbicide tolerant protein SUM1, an encoding gene and use thereof. Said herbicide tolerant protein includes: (a) a protein having an amino acid sequence as set forth in SEQ ID NO:1; or (b) a protein derived from (a) by means of substitution and/or deletion and/or addition of one or more amino acid(s) in the amino acid sequence of (a) and having hydrolase activity to thifensulfuron-methyl. The herbicide tolerant protein can exhibit higher tolerance to multiple sulfonylurea herbicides, can have tolerance up to four times the field concentration, and hence has broad application prospects on plants.
Patent MX-2018012163-A (MX)
Title: Liquid formulations of (s)-n-(5-((r)-2-(2,5-difluorophenyl)-pyrro lidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine- 1-carboxamide.
Inventor: MARK REYNOLDS
IPC: A61K31/519
Filed: 2017-04-04
Abstract: A liquid formulation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1 ,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, pharmaceutically acceptable salts thereof, or a combination thereof and the use of the liquid formulation in the treatment of pain, cancer, inflammation, and certain infectious diseases are disclosed.
Patent MX-2018012976-A (MX)
Title: System for nickel-free zinc phosphate pretreatment.
Inventor: MARK W MCMILLEN
IPC: C23C22/12
Filed: 2017-04-25
Abstract: Disclosed is a substrate pretreatment system, comprising (a) an activating rinse for treating at least a portion of a substrate comprising a dispersion of metal phosphate particles having a D90 particle size of no greater than 10 µm, wherein the metal phosphate comprises divalent or trivalent metals or combinations thereof; and (b) a pretreatment composition for treating at least a portion of the substrate treated with the activating rinse, comprising zinc ions and phosphate ions, wherein the pretreatment composition is substantially free of nickel. Methods of treating a substrate with the substrate pretreatment system also are disclosed. Substrates treated with the substrate pretreatment system also are disclosed.
Patent MX-2018013863-A (MX)
Title: Combination therapies using indazolylbenzamide derivatives for the treatment of cancer.
Inventor: EVERARDUS O M ORLEMANS
IPC: A61P35/00
Filed: 2017-05-18
Abstract: The invention relates to combination therapies useful in the treatment and/or prevention of cancer.
Patent MX-2019000012-A (MX)
Title: Manufacturing fibre-reinforced composite structures.
Inventor: IAIN BOMPHRAY
IPC: B29C70/22
Filed: 2017-07-05
Abstract: The invention relates to a method of manufacturing a three dimensional structure having an internal space, the method comprising the following steps: (a) arranging a preform of fibre reinforced material in a first configuration in which the preform is supported by a support structure; (b) selectively curing the preform when laid out on the support structure to produce an intermediate preform, the intermediate preform comprising at least two selectively cured portions interconnected by at least one non-selectively cured portion; and (c) moving the two selectively cured portions with respect to one another to form the three dimensional composite structure in which the two portions at least partially surround the internal space of the structure. A preform of fibre reinforced material for use in a method of manufacturing a three dimensional structure having an internal space also forms part of the invention. The invention also relates to a device and intermediate preforms for the manufacture of a fibre-reinforced composite structure.
Patent MX-2019002641-A (MX)
Title: Systems and methods for defending crops from crop-damaging pests via unmanned vehicles.
Inventor: Donald R High
IPC: G01S13/56
Filed: 2017-08-29
Abstract: In some embodiments, methods and systems of defending a crop-containing area against crop-damaging pests include an unmanned aerial vehicle including a sensor that detects one or more pests in the crop-containing area and an output device configured to eliminate the pest from the crop-containing area. One or more docking stations configured to accommodate the UAV are provided. A computing device configured to communicate with the UAV and the docking station over a network is provided. The UAV is configured to send pest detection data captured by a sensor of the UAV while patrolling the crop-containing area. In return, the computing device is configured to send a signal to the UAV to indicate instructions to the UAV as to how to move or activate the output device in order to eliminate the detected pest from the crop-containing area.
Patent MX-2019003588-A (MX)
Title: Process for converting carbonaceous material into low tar synthesis gas.
Inventor: STEVE KRESNYAK
IPC: C10J3/06
Filed: 2017-09-29
Abstract: A continuous multi-stage vertically sequenced gasification process for conversion of solid carbonaceous fuel material into clean (low tar) syngas. The process involves forming a pyrolysis residue bed having a uniform depth and width to pass raw syngas there through for an endothermic reaction, while controlling the reduction zone pressure drop, resident time and syngas flow space velocity during the endothermic reaction to form substantially tar free syngas, to reduce carbon content in the pyrolysis residue, and to reduce the temperature of raw syngas as compared to the temperature of the partial oxidation zone.
Patent MX-2019003919-A (MX)
Title: Rugged weather resistant power distribution.
Inventor: NORMAN R BYRNE
IPC: H01R25/00
Filed: 2017-10-09
Abstract: An electrical system for group seating arrangements includes a plurality of conduit assemblies and a plurality of branch assemblies, each made up of hollow casings with electrical connectors and seals at their opposite ends, and with electrical conductors providing continuity to the electrical connectors of each branch and conduit assembly. A mechanical latch or lock coupling at each of the ends, combined with a seal at each coupling or junction, provides a secure and contaminant-resistant mechanical connection and at each conduit-to-conduit or conduit-to-branch junction. The hollow casings of the conduit assemblies and branch assemblies may be made of high-strength material so as to resist damage from impacts when installed in high traffic areas such as stadiums, arenas, theaters, and public transit vehicles.
Patent MX-2019007089-A (MX)
Title: Compact mode-locked laser module.
Inventor: Benjamin CIPRIANY
IPC: H01S3/10
Filed: 2017-12-15
Abstract: Apparatus and methods for producing ultrashort optical pulses are described. A high- power, solid-state, passively mode-locked laser can be manufactured in a compact module that can be incorporated into a portable instrument. The mode-locked laser can produce sub- 50-ps optical pulses at a repetition rates between 200 MHz and 50 MHz, rates suitable for massively parallel data-acquisition. The optical pulses can be used to generate a reference clock signal for synchronizing data-acquisition and signal-processing electronics of the portable instrument.