baber/WOPTO huggingface dataset:
Patent DE-69524795-D1 (DE)
Inventor: DE GREGORIO VITO
IPC: B29C45/33
Filed: 1995-01-26
Granted: 2002-02-07
Abstract: The method of moulding and relative mould (1) for the production of gun cartridge wads (10) consisting, at least, of a die (3) and a punch (7), set opposite one another and able to move towards or away from one another, and a pair of cheeks (5) set opposite one another and able to move towards or away from one another in the same plane along an axis which is transversal to the direction of movement of the die (3) and punch (7), which envisage that, upon completion of the injection and moulding stage and during the opening of the mould (1), the moulded wad (10) is stably supported at both ends, at one end by the die (3) and at the opposite end by the punch (7), at least for the time required to move the cheeks (5) away from the moulded wad (10) until it is completely released. <IMAGE>
Patent DE-69525357-D1 (DE)
Inventor: HAYWARD JOHN
IPC: B21D5/08
Filed: 1995-10-10
Granted: 2002-03-21
Abstract: A method of producing articles in continuous succession by forming from strip material (1) includes partially dividing the strip prior to completion of the forming, to leave adjacent strip portions (1A, 1B) joined by a small connecting portion (15) and parting-off a pair of successive formed articles by severing the portion (15). Apparatus for performing the method includes forming means (5) for forming the strip to the desired profile, means (C) for partially dividing the strip to leave the connecting portion (15), and means (9, 10) for parting-off of a pair of successive formed articles by severing the connecting portion.
Patent DE-69525999-D1 (DE)
Inventor: BIGI ERMES
IPC: B28B13/02
Filed: 1995-06-28
Granted: 2002-05-02
Abstract: A horizontal surface (20) is provided, which is substantially equal to the plan projection of the carriage loading compartment (11) and lies above this when the carriage (10) is in its retracted position, and comprises a plurality of apertures (21) for passage of the materials; with the surface (20) there are associated means (40, 44) for opening and respectively closing the apertures (21) in said surface; the apertures (21) in the perforated surface (20) are distributed as at least two separate pluralities (21', 21''), means (22, 24, 25) being provided for conveying material originating from a respective feed container (30', 30'') into each plurality of apertures (21', 21''). <MATH>
Patent DE-69526521-D1 (DE)
Inventor: FEARON THOMAS
IPC: A61K47/48
Filed: 1995-12-06
Granted: 2002-05-29
Abstract: Coupling of C3d molecules or ligands of CD21 or CD19 to an antigen alters the level of immune response to the immunogen upon its administration to an individual. For C3d, the magnitude of the effect is dependent on the number of C3d molecules included in the conjugate. Conveniently, C3d molecules or CD21/CD19 ligands are coupled to an immunogen in fusion polypeptides which may be produced by expression from coding nucleic acid, for instance by culturing host cells containing the nucleic acid. Other means of associating the molecules include chemical cross-linking and co-expression on the surface of a carrier structure. Administration of compositions comprising, in a preferred embodiment, C3d molecules and an immunogen of interest may be used prophylactically (by virtue of the immunological memory induced) or therapeutically. The administration may be for the purpose of raising antibodies to the immunogen. A T-cell response may also be induced.
Patent DE-69530290-D1 (DE)
Inventor: ALOISI ALESSANDRO
IPC: A61B18/02
Filed: 1995-01-27
Granted: 2003-05-15
Abstract: PCT No. PCT/IT95/00010 Sec. 371 Date Aug. 7, 1996 Sec. 102(e) Date Aug. 7, 1996 PCT Filed Jan. 27, 1995 PCT Pub. No. WO96/22810 PCT Pub. Date Aug. 1, 1996The device for physiotherapy according to the present invention includes an electric current generator (4) with variable and in case modulated frequency, supplied between two electrodes that comprise the sick anatomic part to be treated, the first electrode being of a container (2-5) for a medicament solution in distillate water brought to the freezing point, and the other one in an element (6) with a wide surface that may be applied to the skin for closing the electric circuit, through the passage of the current through the anatomic part, consisting of the flow of ions coming from the frozen medicament crystals, so that nearly the whole of said ions penetrate through the anatomic part being treated, directly reaching the activity areas.
Patent DE-69533673-D1 (DE)
Inventor: DOIDGE CHRISTOPHER VINCENT
IPC: A61K39/106
Filed: 1995-06-08
Granted: 2004-11-25
Abstract: An antigenic preparation for use in the treatment or prevention of Helicobacter infection in a mammalian host, comprises the catalase enzyme of Helicobacter bacteria, particularly the catalase enzyme of H. pylori or H. felis, or an immunogenic fragment thereof.
Patent DE-69535541-D1 (DE)
Inventor: AURIK ERIK ARNOLDUS
IPC: A01J5/017
Filed: 1995-02-17
Granted: 2007-08-30
Abstract: A cleaning device for cleaning a teat of an animal, the cleaning device (25) comprising:     a feed conduit (29) for supplying a cleaning medium; a housing (26) having an open top side (27) for receiving the teat and an open bottom side for draining the cleaning medium admitted into the housing via the feed conduit (29); and at least one outlet opening for the cleaning medium arranged in the housing (26) and in flow communication with the feed conduit (29), so obtaining an optimal cleaning treatment and in particular by means of an automatically operated milking arm.   <IMAGE>
Patent DE-69601637-D1 (DE)
Inventor: BARLOW EVE
IPC: G01N33/542
Filed: 1996-06-27
Granted: 1999-04-08
Abstract: The assay described herein is predicated on an observation that when acridinium ester labeled tracers are bound to their corresponding binding conjugate immobilized on a metal oxide solid phase, the measurable chemiluminescent light emission of the labeled tracer bound to the solid phase is quenched as compared to the free fraction tracer that is unattached to the solid phase. According to the invention, a non-separation specific binding assay to detect or quantify the presence of an analyte is provided where the entire reaction mixture is flashed (including unreacted tracer) and modulated signal (because of the quench effect) is associated with a reference, thus determining the amount or presence of said analyte in said sample. Disadvantages inherent in heterogeneous assays employing multiple separations may be avoided using this non-separation method.
Patent DE-69606566-D1 (DE)
Inventor: BRYANT HENRY UHLMAN
IPC: A61P19/10
Filed: 1996-03-06
Granted: 2000-03-16
Abstract: Benzofuran derivs. of formula (I) and their salts are new: R1 = OH, halogen, 2-7C alkanoyloxy, aroyloxy, 4-6C alkylsulphonyloxy, (1-6C alkoxy)carbonyloxy, aryloxycarbonyloxy or mono- or di(1-6C alkyl)carbamoyloxy; R2 = aryl, 3-6C cycloalkyl or 4-hydroxycyclohexyl;l R3 = O(CH2)2 or O(CH2)3; R4, R5 = n-butyryl, n-valeryl or 1-6C alkyl, or NR4R5 = piperidino, morpholino, pyrrolidino, 3-methylpyrrolidino, 3,3-dimethylpyrrolidino, 3,4-dimethylpyrrolidino, azepino or pipecolino; R6 = C=CHR, CHR' or C(OH)R'; R = H or 1-5C alkyl and R' = 1-5C alkyl, 2-5C alkenyl or aryl.
Patent DE-69609382-D1 (DE)
Inventor: YAMASHITA HIROYUKI
IPC: C07D307/52
Filed: 1996-08-30
Granted: 2000-08-24
Abstract: The invention relates to a substituted amidine derivative which has an excellent platelet aggregation inhibiting action on the basis of fibrinogen antagonism and is particularly excellent in effectiveness on oral administration, and the platelet aggregation inhibitor containing the substituted amidine derivative of the invention as an effective ingredient is effective for prevention and remedy of thrombosis, and restenosis or reocclusion after percutaneous transluminal coronary angioplasty or percutaneous transluminal coronary recanalization.
Patent DE-69621435-D1 (DE)
Inventor: MELSKY S
IPC: A61M5/142
Filed: 1996-03-26
Granted: 2002-07-04
Abstract: An implantable infusion device includes a housing having opposite first and second walls and a relatively large blind passage extending into the housing from the first wall toward the second wall. A first self-sealing septum blocks the passage at the first wall and a second self-sealing septum blocks the passage at a location therein spaced from the first septum thereby defining an infusate chamber between the first and second septa and a blind chamber between the second septum and the housing second wall. A fluid pathway containing a normally closed valve extends from the infusate chamber to the exterior of the housing and a lever connected to the valve is located in the blind chamber. That lever may be depressed to open the valve only by a needle inserted through the two septa into the blind chamber which needle has a side opening aligned with the infusate chamber when such depression occurs.
Patent DE-69624508-D1 (DE)
Inventor: COOK E
IPC: C12N5/02
Filed: 1996-08-27
Granted: 2002-11-28
Abstract: The invention relates to a method preserving white blood cells with CLA. <IMAGE>
Patent DE-69625741-D1 (DE)
Inventor: GUAZZO FRANCESCO
IPC: E04B5/23
Filed: 1996-05-10
Granted: 2003-02-20
Abstract: The unit consists of a cylindrical rod (1) of a suitable length, made with an enlarged head (2) on its upper end and a tip of reduced diameter on its lower end which is attached to a central hole in a square fastening plate (3). The fastening plate has a hole (6, 7) on each side of the rod for a fixing such as a screw, and spikes (4) made by folding over the corners of the fastening plate. The unit is fixed to a timber beam by driving in the spikes and fixing screws through the holes, after which a concrete slab can be cast in situ on the beam, holding it reliable in place.
Patent DE-69627983-D1 (DE)
Inventor: SUEZAWA MITSURU
IPC: G03F7/40
Filed: 1996-11-08
Granted: 2003-06-12
Abstract: A treating liquid for making a waterless planographic printing plate with a photosensitive layer and a silicone rubber layer laminated in this order on a substrate, comprising at least one amine compound with two or more amino groups and one or more hydroxyl groups in one molecule. A treating liquid for making a waterless planographic printing plate excellent in plate surface coatability and developability can be obtained.
Patent DE-69636225-D1 (DE)
Inventor: REISS BERND
IPC: C12N15/09
Filed: 1996-08-30
Granted: 2006-07-20
Abstract: The present invention relates to a novel process for the production of transgenic organisms or transgenic cells, to transgenic orgaisms or transgenic cells obtainable by the process of the present invention, to the use of vectors comprising DNA encoding a recombination promoting enzymes for curing impairments caused by environmental influences in plants or plant cells and for gene therapy in mammals or mammalian cells, and to novel vectors.
Patent DE-69637357-D1 (DE)
Inventor: HEMMINGS BRIAN ARTHUR
IPC: C12N1/21
Filed: 1996-11-05
Granted: 2008-01-17
Abstract: There is provided a process for activating a kinase of a signalling pathway comprising treatment thereof with a phosphatase inhibitor. Moreover, we describe methods for screening candidate immunosuppressive and antiproliferative agents using thus activated kinases.
Patent DE-69703549-D1 (DE)
Inventor: KIMIEC L
IPC: C08L23/08
Filed: 1997-06-20
Granted: 2000-12-21
Abstract: A cable comprising one or more communications media or electrical conductors, or a core of two or more communications media or electrical conductors, each communications medium, electrical conductor, or core being surrounded by at least two layers, an inner insulating layer and an outer jacketing layer, is disclosed. The jacketing layer comprises an in situ blend of two copolymers of ethylene and one or more alpha-olefins having 3 to 12 carbon atoms. The blend has an Mw/Mn ratio in the range of about 8 to about 22; a melt index in the range of about 0.2 to about 3.5 grams per 10 minutes; a melt flow ratio in the range of about 55 to about 135; a molecular weight in the range of about 90,000 to about 250,000; and a density of at least 0.915 gram per cubic centimeter.
Patent DE-69714611-D1 (DE)
Inventor: MARCHETTI LUIGI
IPC: A41D27/00
Filed: 1997-04-09
Granted: 2002-09-12
Abstract: The equipment comprises in combination: a twin needle (15, 17) fed with two needle threads (F1, F2); an upper looper (30) fed with a looper thread (F3), and a lower spreader (31); a throat plate (36) with two slots (38, 40) for the needles (15, 17) and the stitch finger (42) on the line of the cut (T) of increased width (D); and a thread-pulling arm (25) for pulling off an increased amount of the thread (F3) for the looper at each angular stroke.
Patent DE-69725739-D1 (DE)
Inventor: GRANOFF DAN
IPC: A61P31/04
Filed: 1997-08-27
Granted: 2003-12-11
Abstract: Novel bactericidal antibodies against Neisseria meningitidis serogroup B ("MenB") are disclosed. The antibodies either do not cross-react or minimally cross-react with host tissue polysialic acid and hence pose minimal risk of autoimmune activity. The antibodies are used to identify molecular mimetics of unique epitopes found on MenB or E. coli K1. Examples of such peptide mimetics are described that elicit serum antibody capable of activating complement-mediated bacteriolysis of MenB. Vaccine compositions containing such mimetics can be used to prevent MenB or E. coli K1 disease without the risk of evoking autoantibody.
Patent DE-69728407-D1 (DE)
Inventor: HAYEK ZAMIR
IPC: A61H31/00
Filed: 1997-07-16
Granted: 2004-05-06
Abstract: A cuirass type ventilator compresses a shell member having a peripheral edge and a sealing device secured to the peripheral edge, the sealing device compressing a scaling member depending from the peripheral edge of the shell, the sealing member having a sealing region for sealing against a patient's body, a securing region whereat the sealing member is secured to the shell and a resilient pleated region intermediate the sealing region and securing region whereby, in use, the resilience of the pleated region urges the sealing region into scaling engagement with a patient's body.
Patent DE-69736837-D1 (DE)
Inventor: TALAMONTI ANTHONY R
IPC: A61M1/00
Filed: 1997-08-12
Granted: 2006-11-30
Abstract: A disposable device for controlling the rate of suction to and from a bodily organ, such as the stomach, during a lavage procedure that involves the use of a movable controller that slides back and forth over an opening in the main body of the device. The interior opening of the device which is placed in a flowline that extends from the stomach upstream to a downstream collection vessel has a tapered flow path that allows for the uninterrupted flow of pill fragments or stomach contents through the flowline. A lateral flow path that extends from an opening in the exterior of the main body to the main flow path enables an operator to vary the suction pressure to or from the patient by varying the size of the exterior opening through the use of the movable controller.
Patent DE-69825433-D1 (DE)
Inventor: MAGVASI GYULA
IPC: A61K35/54
Filed: 1998-03-24
Granted: 2004-09-09
Abstract: The invention relates to an active substance inhibiting tumorous proliferation in ectoderm derived tissues and to a composition containing such substance. A process for producing the above active substance comprises the following steps:fertilized ovum of human beings or sea water fishes or fresh water fishes is subjected to cell wall destruction preferably 24 hours, more preferably 14-16 hours after fertilization, then the material is ultracentrifuged, the supernatant is separated, the sediment is homogenized, then ultracentrifuged several times, and each time the supernatant and the sediment are separated, thereafter all supernatant fractions are combined and centrifuged preferably at 8,000-15,000 rpm, the supernatant obtained is separated and diluted preferably with physiological solution, preferably in 1:2 ratio by weight, then the active substance is separated from contaminants, preferably the obtained material is subjected to a series of gel filtration at least twice, then the filtered substance is lyophilized.
Patent DE-69836986-D1 (DE)
Inventor: CHEN YUGUANG
IPC: A01N51/00
Filed: 1998-12-14
Granted: 2007-03-15
Abstract: The pesticide to be used without causing phytotoxicity to the seed. Insecticidal coating for a corn seed comprises: (1) one or more binders comprising polymers or copolymers of polyvinylacetate, methyl cellulose, polyvinyl alcohol, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidone or polysaccharide; (2) an insecticidal heterocycle of formula (I) or its tautomer or salt, optionally in combination with imidacloprid or its analogues, organophosphate, phenyl pyrazole and/or a pyrethroid: and (3) one or more fillers, where the binder forms a matrix for the insecticide and filler on the corn seed and the filler is present in an amount to prevent or reduce the phytotoxic effect on the corn seed caused by the insecticide. The coated seed is claimed per se. [Image] A : optionally mono- to tetrasubstituted, optionally aromatic, mono- or bicyclic heterocycle, where 1-2 of the substituents are Q aand 1-4 of the substituents are Q b; Q a1-3C haloalkyl, cyclopropyl, halocyclopropyl, 2-3C alkenyl, 2-3C alkynyl, 2-3C haloalkenyl, 2-3C haloalkynyl, 1-3C haloalkoxy, 1-3C alkylthio, 1-3C haloalkylthio, allyloxy, propargyloxy, allylthio, propargylthio, haloallyloxy, haloallylthio, CN or NO 2; Q b1-3C alkyl, 1-3C alkoxy or halogen; R = H, 1-6C alkyl, phenyl-1-4C alkyl, 3-6C cycloalkyl, 2-6C alkenyl or 2-6C alkynyl; and X : N-NO 2or N-CN. Independent claims are included for the following: (1) control of insect pests from damaging a corn plant comprising applying the above coating to a corn seed; (2) preparation of coated corn seeds; and (iii) a method of protecting emerging seedlings of a crop plant form one or more insect organisms in the seed growing soil environment comprising applying the above coating to he seeds. ACTIVITY : Insecticide;.
Patent DE-69840333-D1 (DE)
Inventor: WEINER DAVID B
IPC: C07K14/16
Filed: 1998-10-09
Granted: 2009-01-22
Abstract: The present invention is directed to substantially pure human Vpr Interacting Protein (hVIP), and fragments thereof. Also disclosed are isolated nucleic acid molecules that encode hVIP, or a fragment thereof; nucleic acid probes and primers directed to nucleic acid molecules that encode hVIP, or a fragment thereof; oligonucleotide molecules that consist of a nucleotide sequence complementary to a portion of the nucleotide sequence that encodes hVIP; vectors comprising nucleic acid molecules encoding hVIP; recombinant expression vectors that comprise nucleic acid sequences that encode hVIP; host cells that comprise recombinant expression vectors which include nucleic acid sequences that encode hVIP; genetic therapy vectors comprising nucleic acid molecules encoding hVIP; isolated antibody which binds to an epitope on hVIP; pharmaceutical compositions comprising a pharmaceutically acceptable carrier and nucleic acid molecules complementary to a portion of hVIP; methods of making hVIP; and methods of inhibiting expression of hVIP oligonucleotides complementary to a portion of the nucleotide sequence that encodes hVIP.
Patent DE-69900555-D1 (DE)
Inventor: SORENSEN JORREN
IPC: F16H19/00
Filed: 1999-03-25
Granted: 2002-01-17
Abstract: An elongate spindle member having rigidity and stability against pressure and tensile loads as well as bending and torsional loads is made by winding-up a plurality of mutually interlocking chain links ( 1, 12 ), during axial advancement of the chain links, into a helical winding ( 5, 16 ) by a winding guide ( 14 ). The elongate spindle member, formed by the helical winding, extends between two objects, one of which is connected with the winding guide ( 14 ). The first turn of the helical winding is connected with a coupling member for connection with the other of the two objects. The helical winding is formed by drivingly connecting the chain links to a rotatable driving device in the winding guide and retaining each chain link in engagement with neighboring links in the same turn as well as adjacent chain links in neighboring turns.
Patent DE-69902521-D1 (DE)
Inventor: LENNON CAMPBELL
IPC: C07F9/50
Filed: 1999-04-01
Granted: 2002-09-19
Abstract: A process for the preparation of a compound having the formulawherein Ar is an aryl group bearing the PR3R4 and COX groups in a 1,2-relationship, and optionally bearing also one or more non-interfering groups, R3 and R4 are each a hydrocarbon group optionally substituted by any non-interfering group, and X is OH or a non-interfering group, comprises (i) the reaction of NaPR3R4 with F-Ar-COX, or (ii) when X is an amine group, the reaction of R3R4P-Ar-COOY, OY being OH or a leaving group, with a solution of the amine obtained in situ by adding a base to a salt thereof.Certain ligands prepared by such a process are in a novel, crystalline form.
Patent DE-69904839-D1 (DE)
Inventor: THOMAS DAVID WILLIAM
IPC: B23Q35/00
Filed: 1999-09-07
Granted: 2003-02-13
Abstract: A cutting apparatus comprises a machine bed support (1) having a quarter circle profile as seen from above and carrying a workpiece supporting platform (5). The workpiece may be a steel plate (6). The rear of the apparatus has an upstanding post (2) forming a vertical pivot to which is rigidly connected upper and lower arms (3) and (4) which may thus swing in a horizontal plane. A frame (7) is supported on the arms (3) and (4) by rollers R for free movement towards and away from the post (2). The lower limb of frame (7) carries the workpiece cutting device (16) and the upper limb of this frame caries a template following sensor device (8). The sensor device (8) is arranged to follow the required profile defined by a drawing or template on table (10) and this is effected by control of two drive motors using photo-electric template following means one motor driving a wheel (12) which frictionally engages the template and the other motor controlling the orientation of the wheel (12). The wheel is thus rotated to travel across the surface of the template and controlled directionally so that the template pattern is followed to produce a corresponding tracking movement of the frame (7) and thus the cutting device (16). In this arrangement the wheel (12) directly moves the frame (7) together with the cutting device 16 avoiding complex drives and couplings.
Patent DE-69906436-D1 (DE)
Inventor: CHORNEY HARVEY J
IPC: F16H57/04
Filed: 1999-08-12
Granted: 2003-05-08
Abstract: A splitter gearbox (30) for a four wheel drive, hydrostatically driven tractor integrates both the input drive train and the output drive train into a single gearbox. The splitter gearbox (30) is mounted to the rear axle housing (17) to allow the sharing of a common oil sump. The front and rear axles (12, 17) of the tractor are driven from a single hydrostatic motor (25) associated with a gear drive system that provides a shaft (38) extending forwardly and rearwardly out of the splitter gearbox (30) to drive, respectively, the front and rear axles (12, 17) of the tractor. An auxiliary pump drive (40) is mounted to the side of the splitter gearbox (30) and is driven from an idler gear (43) appropriately positioned within the auxiliary pump drive housing (44). <IMAGE>
Patent DE-69907781-D1 (DE)
Inventor: BRUVRY MICHEL
IPC: F16L33/207
Filed: 1999-02-23
Granted: 2003-06-18
Abstract: The coupling comprises a rigid component (4) with a rigid cylindrical projection (6) which goes inside the flexible tube (2), and a locking sleeve (12) which goes over the outside of the tube and has an indicator (28) with a chamfered inner ring (38). When the flexible tube has been inserted into the coupling and through the ring to make contact with an end seal (16) the indicator is retracted inside the locking sleeve, showing that the tube is correctly placed.