baber/WOPTO huggingface dataset:
Patent AU-2019270404-A1 (AU)
Title: Blood biomarkers of stroke
Inventor: TIMSIT SERGE
IPC: G01N33/68
Filed: 2019-05-16
Abstract: Stroke is a devastating disorder that significantly contributes to death, disability and health care costs. The current challenge is to prevent late cell death, with concomitant therapy to widen the therapeutic window. A potential diagnostic method for stroke is the use of RNA in the blood as a biomarker, which is an emerging field in medicine. Here the inventors explore the expression of genes after the onset of cerebral ischemia in the brain and blood. The study of macaque microarray expression data from brain and blood revealed that ischemic and nonischaemic samples can be distinguished based on their expression profiles, and the majority of highly differentially expressed genes are up- regulated in the ischemic scenario 6 hours after ischemia. A comparison of differentially expressed genes in the brain and the blood revealed a significant overlap of gene expression patterns. The data showed that there is a common signature between the ischemic brain and the blood and support the development of blood transcriptomics as a tool for biopsy transcriptome expression profiling to characterize patients with ischemic stroke to develop a companion biomarker for the assessment of neuroprotection drugs in patients.
Patent AU-2019280080-A1 (AU)
Title: Ion source for an ion mobility spectrometer
Inventor: GARDNER BENJAMIN D
IPC: H01J49/40
Filed: 2019-12-13
Abstract: An ion mobility spectrometer for analyzing a vapor sample including a multi-ring ion 
source for receiving a vapor sample, wherein the multi-ring ion source includes a series of rings, 
wherein each ring of the multi-ring ion source includes an ionizing layer on an inner surface 
5 thereof, for charging at least a portion of the vapor sample and creating an ionized vapor sample.
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Patent AU-2019287491-A1 (AU)
Title: A 19-nor C3,3-disubstituted C21 -N-pyrazolyl steroid and methods of use thereof
Inventor: KANES STEPHEN JAY
IPC: A61K31/58
Filed: 2019-06-12
Abstract: Provided herein are methods for treating depression, such as postpartum depression or major depressive disorder, in a subject in need thereof, comprising administering to the subject an effective amount of Compound 1 or a pharmaceutically acceptable salt thereof: (Compound I).
Patent AU-2019311219-A1 (AU)
Title: Closure
Inventor: DRUITT RODNEY
IPC: B65D47/14
Filed: 2019-07-17
Abstract: A closure ( 1 ) for a liquid container according to the invention comprises a base portion (2) and a top portion (8). The base portion (2) comprises a top deck (3) and an outer skirt (5) extending from an outer end (6) of the top deck (3) in a lower direction away from the top deck (3). The outer skirt (5) comprises a fastening means (7) to interconnect the closure (1) to the container neck. The top deck (3) further has a spout (4) extending in an upper direction away from the top deck (3). The top portion (8) comprises an annular base (9) interconnectable to the base portion (2) and a cover (1 0) having an outer wall (11). At least one tamper element (13) extends from the annular base (9) in the upper direction above the annular base (9) along the outer wall (11) but spaced a distance apart from said outer wall (11). The tamper element (13) is also initially interconnected to the outer wall (11) by a predetermined breaking linkage (14).
Patent AU-2019337584-A1 (AU)
Title: Magnetically-actuated latch mechanism for display module
Inventor: FLOWERS ASHTON
IPC: G09F9/302
Filed: 2019-09-11
Abstract: A display module comprises a support, a plurality of light-emitting elements coupled to the support and a latch mechanism (150) to removeably couple the support to a chassis (154). The latch mechanism includes a movable member (156), a latch member (168), and a linkage mechanism (166). The movable member is moved from a first position to a second position when magnetically engaged by a tool magnet. The latch member moves between a first latch member position and a second latch member position and can engage a chassis mating structure when in the first latch member position. The linkage mechanism mechanically connects the movable member to the latch member so that they move together such that the latch member is in the first latch member position when the movable member is in the first position and is in the second latch member position when the movable member is in the second position.
Patent AU-2019341613-A1 (AU)
Title: Method for manufacturing building element with wooden frame, building element with wooden frame, and building element system
Inventor: HERRANEN PASI
IPC: E04B1/80
Filed: 2019-09-18
Abstract: A method for manufacturing a building element (1 ) with a wooden frame, the method comprising forming the frame of the element of wooden panels (2, 3), filling the space inside the frame with insulation material (10), coating the wooden panels (2, 3) which define the outer surfaces of the frame of the building element (1 ) to be substantially air-tight, filling the space inside the frame with expanded perlite (10), and applying vacuum in the space inside the building element by a vacuum pump (7) connected to the element. The invention also relates to such a building element with a wooden frame, as well as a building element system consisting of a plurality of such building elements with a wooden frame.
Patent AU-2019369820-A1 (AU)
Title: Device, method, program, and system for detecting unidentified water
Inventor: YE JIAXING
IPC: E03F1/00
Filed: 2019-10-31
Abstract: Provided is a technology for realizing detection of unidentified water without using a flowmeter. One embodiment of the present invention pertains to an unidentified water detection device having: a feature quantity extraction unit which extracts, from acoustic data including running water sound, an acoustic feature quantity pattern that indicates temporal changes in an acoustic feature quantity; and an unidentified water prediction unit which, using a machine learning model learned from the acoustic feature quantity pattern extracted from data that contains acoustic data including running water sound during lack of rainfall and/or acoustic data of running water sound under a condition different from during lack of rainfall, predicts the presence/absence of unidentified water from the acoustic feature quantity pattern of acoustic data of a prediction object, wherein the acoustic feature quantity pattern indicates temporal changes in the acoustic feature quantity in terms of time period and day of the week.
Patent AU-2019385699-A1 (AU)
Title: Food products comprising avian stem cells
Inventor: GUEHENNEUX FABIENNE
IPC: A23K10/10
Filed: 2019-11-22
Abstract: A synthetic meat product for human and animal consumption and methods for producing such food product are disclosed. The synthetic food product comprises or essentially consists of a cell biomass of avian cells grown in vitro in a chemically-defined serum free culture medium under controlled conditions and do not contain any hazard contaminations.
Patent AU-2019386830-A1 (AU)
Title: Methods for ex vivo expansion of natural killer cells and use thereof
Inventor: SHPALL ELIZABETH
IPC: A61K35/17
Filed: 2019-11-21
Abstract: Provided herein are ex vivo methods for the expansion of cord blood-derived natural killer cells and methods of their use. Examples of embodiments include stimulating mononuclear cells from cord blood in the presence of antigen presenting cells (APCs) and IL-2 and re-stimulating the cells with APCs to produce expanded NK cells. In specific embodiments, the method does not utilize human leukocyte antigen (HLA) matching.
Patent AU-2019399938-A1 (AU)
Title: Method for the at least partially automated planning of an installation of lift components of a lift system
Inventor: BÜTLER ERICH
IPC: B66B19/00
Filed: 2019-12-02
Abstract: The invention relates to a method for the at least partially automated planning of an installation of lift components (16) in a lift shaft (10) bounded by shaft walls (18a, 18b, 18c, 18d), having the following steps: • - recording profiles of the shaft walls (18a, 18b, 18c, 18d), • - determining positions of door openings (52a, 52b, 52c) in the lift shaft (10), • - defining a setpoint profile of a guide rail (86a, 86b) depending on the determined positions of the door openings (52a, 52b, 52c) and • - automatically defining setpoint positions of the lift components (16) depending on the defined profile of the guide rail (86a, 86b). At least some of the lift components (16) to be installed are in the form of adjustable lift components that have a part (88) attachable to a shaft wall (18a, 18b, 18c, 18d) and a part (90) movable in a defined adjustment range (100) with respect to the attachable part (88). Setpoint positions of the movable parts (90) are defined for adjustable lift components (16). According to the invention, it is automatically checked whether, when positioning the movable part (88) of the lift component (16) at its setpoint position (102, 108), said adjustment range (100) is sufficient to attach the attachable part (88) to the shaft wall (18a, 18b, 18c, 18d). The results of said check are output for further processing.
Patent AU-2019409988-A1 (AU)
Title: A handheld motorised food cutting device
Inventor: ANTKOWIAK MARGARET
IPC: B26D3/26
Filed: 2019-12-16
Abstract: A handheld motorised food cutting device (10) is disclosed herein. The handheld motorised food cutting device (10) comprises a body (12) to be gripped in a user's hand so that the device (10) is supported by the hand, the body (12) having a passage (14) extending inwardly of the body (12) from an inlet opening (16) through which a food item to be processed is inserted for movement along the passage (14) in a processing direction (18); a blade assembly (30) moveably mounted in the body (12) for reciprocating movement along a cutting path that is transverse of said processing direction (18), with the blade assembly (30) being exposed to the passage (14) so as to be engaged by the food item moved in said processing direction (18); and a drive assembly (50) to drive said blade assembly (30) along said cutting path, wherein the body (12) provides a surface to abut a palm of said hand, with fingers of the hand extending at least partly about said body so that the body (12) is gripped, and wherein said processing direction (18) is transverse of said surface.
Patent WO-2021113924-A1 (WO)
Title: Cultures organoïdes
Inventor: CLARKE JORDAN
IPC: C12N5/00
Filed: 2020-12-11
Abstract: La présente invention concerne des procédés et des milieux améliorés pour la culture de cellules souches et la prolifération d'organoïdes. En particulier, les procédés fournissent des procédés améliorés de culture de cellules souches normales et tumorales ou cancéreuses et leur prolifération en organoïdes. L'invention concerne spécifiquement des procédés de suspension ayant une utilité particulière pour une multiplication organoïde évolutive, une biocontamination, une manipulation expérimentale, une miniaturisation et un criblage de médicament à haut rendement basé sur l'imagerie.
Patent AU-2020201338-A1 (AU)
Title: Swimming pool cleaner and associated components
Inventor: HAYES GRAHAM M
IPC: E04H4/16
Filed: 2020-02-24
Abstract: Exemplary embodiments are directed to pool cleaners that remove debris from water using a plurality of cyclonic flows, or that include a removable impeller subassembly, 5 a check valve for a debris canister, a particle separator assembly having a handle that locks to the pool cleaner, a modular roller drive gear box, or a roller latch that secures a roller to the pool cleaner. Exemplary embodiments are also directed to the check valve and the roller latch themselves. Exemplary embodiments are directed to a filter medium for pool cleaners that includes embossments providing flow channels 10 for water, and to roller assemblies for pool cleaners. Exemplary embodiments are directed to pool cleaners including alternative pump motor engagements. Exemplary embodiments are directed to pool cleaners power supplies that include a potted and contoured power board assembly, and to kickstands therefor. Exemplary embodiments are directed to a pool cleaner caddy, and removable wheels therefor. MEl 24818998v.1
Patent AU-2020215551-A1 (AU)
Title: Methods of treating breast cancer with tucatinib
Inventor: WALKER LUKE
IPC: A61K45/06
Filed: 2020-01-24
Abstract: The invention provides tucatinib and its use in methods of treating cancer, such as breast cancer. The invention also provides compositions and kits comprising tucatinib for use in treating cancer, such as breast cancer.
Patent AU-2020223060-A1 (AU)
Title: Compositions and methods for treating hemoglobinopathies
Inventor: SLAYMAKER IAN
IPC: C12N9/78
Filed: 2020-02-13
Abstract: The present invention features compositions and methods for editing deleterious mutations associated with hemoglobinopathies, such as sickle cell disease (SCD). In particular embodiments, the invention provides methods for correcting mutations in a beta globin polynucleotide using modified adenosine base editors termed "ABE8" having unprecedented levels (e.g., >60-70%) of efficiency.
Patent AU-2020224769-A1 (AU)
Title: Reinforced biocompatible scaffold
Inventor: BOUGHTON ELIZABETH ANNE
IPC: A61L27/56
Filed: 2020-02-21
Abstract: A reinforced biocompatible scaffold facilitates integration of biological tissue. The reinforced scaffold comprises a porous biocompatible scaffold and an arrangement of at least one biocompatible filament embedded within and fixed to the biocompatible scaffold, and/or at least one biocompatible conduit embedded within and fixed to the biocompatible scaffold.
Patent AU-2020229714-A1 (AU)
Title: Cancer therapy using 3,5-disubstituted benzene alkynyl compound and pembrolizumab
Inventor: YONEKURA KAZUHIKO
IPC: A61K45/00
Filed: 2020-02-28
Abstract: The present disclosure addresses the problem of providing a new combination therapy that exhibits a superior anti-tumor effect in cancer patients who have a resistance to immune checkpoint inhibitors, said combination therapy involving (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidine-1-yl(pyrrolidine-1-yl)prop-2-en-1-one or a salt thereof. The present disclosure provides an anti-tumor agent for concomitant administration with pembrolizumab to cancer patients who have a resistance to immune checkpoint inhibitors, said anti-tumor agent including (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidine-1-yl(pyrrolidine-1-yl)prop-2-en-1-one or a salt thereof as an active component.
Patent AU-2020244421-A1 (AU)
Title: Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (crc) and other cancers
Inventor: MAHR ANDREA
IPC: A61K39/00
Filed: 2020-09-29
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in 
immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of 
cancer. The present invention furthermore relates to tumour-associated T-cell peptide epitopes, 
alone or in combination with other tumour-associated peptides that can for example serve as active 
pharmaceutical ingredients of vaccine compositions that stimulate anti-tumour immune response, 
or to stimulate T-cells ex vivo and transfer into patients. Peptides bound to molecules of the major 
histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T
cell receptors, and other binding molecules.
Patent AU-2020249190-A1 (AU)
Title: A dispenser
Inventor: CROSER ANGUS
IPC: A01K5/02
Filed: 2020-03-27
Abstract: A bait dispensing station including a cavity for holding a pellet of bait. The cavity can be enclosed preventing external access to the pellet. The statin also includes a compartment for holding a plurality of pellets and a means of dispensing a pellet into the cavity. A new pellet can only be dispensed into the cavity when no pellets are in the cavity. The cavity incudes a sensor to determine if there is a pallet in the cavity. The dispensing station includes a light sensor that controls access to the cavity and wherein access to the cavity is enabled essentially at night.
Patent AU-2020259801-A1 (AU)
Title: Chemical looping process for the production of hydrogen
Inventor: LIM KOK-SENG
IPC: B01J8/18
Filed: 2020-04-15
Abstract: A chemical looping process for the production of hydrogen and the co-production of carbon dioxide comprising: a first redox loop that comprises: feeding of a first solid oxygen carrier to a first reaction zone (R1) in which a first carbonaceous fuel is also fed, which reacts with the first solid oxygen carrier fed at its maximum oxidising state (fully-oxidised form), leading to the formation of the combustion products carbon dioxide and water and the solid oxygen carrier at a lower oxidising state (reduced form); and feeding of the first solid oxygen carrier in reduced form to a second reaction zone (R2) into which air is also fed, obtaining, from the oxidation of the first solid oxygen carrier, heat and the solid oxygen carrier in fully-oxidised form to be recycled to the first reaction zone (R1); and a second redox loop that comprises: feeding of a second solid oxygen carrier to a third reaction zone (R3) in which a second carbonaceous fuel is also fed, which reacts with the second solid oxygen carrier fed at its an intermediate oxidising state (oxidised form), leading to the formation of the combustion products carbon dioxide and water and the solid oxygen carrier at a lower oxidising state (reduced form); and feeding of the second solid oxygen carrier in reduced form to a fourth reaction zone (R4) into which steam is also fed, which reacts with the reduced form of the solid oxygen carrier, producing hydrogen and the solid oxygen carrier at an intermediate oxidising state (oxidised form) to be recycled to the third reaction zone (R3) and/or the first reaction zone (R1), wherein the first reaction zone (R1) and the third reaction zone (R3) are interconnected allowing transfer of at least a portion of the first solid oxygen carrier from the first reaction zone (R1) to the third reaction zone (R3).
Patent AU-2020277298-A1 (AU)
Title: Flexible pitch product metering system
Inventor: BONNAIN JEAN-CHRISTOPHE
IPC: B65G35/06
Filed: 2020-05-15
Abstract: A product management system (100) includes -a continuous first track (104), including a lug queuing section (108), a lug engagement section (110), and a product engagement section (112), each section being configured and adapted to effectuate specific lug movement steps, -a continuous chain (116) partially following the track configured and adapted to actuate lugs (106) about at least a portion of the track, - a series of lugs (106) moveably disposed along the track (104) configured for moving a product along the product engagement section of the track, - a star wheel (120) disposed at the lug engagement section (110) of the track (104) configured for metering lugs (106) to engage the chain (116) from the queuing section (108) of the track (104) and to control a variable pitch between each of the lugs along the transferring chain, - and a magnetism source (122) configured to direct the lugs (106) to the queuing section (108), and to the end of the queuing section (108).
Patent AU-2020282051-A1 (AU)
Title: Composition containing fluoxetine and vitamin D 3 or its derivatives and application thereof
Inventor: SHANG JING
IPC: A61P17/00
Filed: 2020-05-07
Abstract: Disclosed are a composition, a use of the composition in preparation of a medicament for treating and/or alleviating a hypoallergenic disease, and a pharmaceutical preparation containing the composition. The composition contains fluoxetine and VD
Patent AU-2020283752-A1 (AU)
Title: Methods of generating enucleated erythroid cells
Inventor: LIPSITZ JONATHAN
IPC: C12M3/00
Filed: 2020-05-22
Abstract: Provided herein are methods of generating a population of enucleated erythroid cells.
Patent AU-2020289829-A1 (AU)
Title: A tool for severing or assisting in the severing of a conduit
Inventor: OAG JAMIE
IPC: E21B29/02
Filed: 2020-12-17
Abstract: A tool for severing or assisting in the severing of a conduit is described. The 
tool comprises a housing defining a void, the void arranged, in use, to at least 
partially encircle a conduit and an at least one void access, the/each void 
access having an inlet and an outlet, the/each void access inlet being in fluid 
communication with the housing and the/each void access outlet being in fluid 
communication with the housing void. The tool further comprises an at least 
one propellant source located within the housing, an ignition mechanism for 
igniting the/each propellant source and an at least one modifying material.  
Upon ignition, the/each propellant source deflagrates, creating an at least one 
stream of combustion products, the/each stream of combustion products 
flowing out of the tool through the/each void access in to the void, the/each 
void access channelling the/each stream of combustion products towards the 
conduit, the/each stream of combustion products combining with the/each 
modifying material to sever or assist in severing the conduit.
Patent AU-2020289848-A1 (AU)
Title: Video data stream concept
Inventor: SCHIERL THOMAS
IPC: H04L47/43
Filed: 2020-12-18
Abstract: Video Data Stream Concept 
Abstract 
5 
Decoder retrieval timing information, ROI information and tile identification information 
are conveyed within a video data stream at a level which allows for an easy access by 
network entities such as MANEs or decoder. In order to reach such a level, information of 
such types are conveyed within a video data stream by way of packets interspersed into 
10 packets of access units of a video data stream. In accordance with an embodiment, the 
interspersed packets are of a removable packet type, i.e. the removal of these interspersed 
packets maintains the decoder's ability to completely recover the video content conveyed 
via the video data stream.  
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Patent AU-2020296247-A1 (AU)
Title: Method for the generation of a trivalent antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
Inventor: AUER JOHANNES
IPC: C07K16/00
Filed: 2020-06-17
Abstract: Herein is reported a method for producing a trivalent antibody comprising the steps of cultivating a mammalian cell comprising a deoxyribonucleic acid encoding the trivalent antibody, and recovering the trivalent antibody from the cell or the cultivation medium, wherein the deoxyribonucleic acid encoding the trivalent 5 antibody is stably integrated into the genome of the mammalian cell and comprises in 5'- to 3'-direction a first expression cassette encoding the first heavy chain, a second expression cassette encoding the first light chain, a third expression cassette encoding the first light chain, a fourth expression cassette encoding the second heavy chain, a fifth expression cassette encoding the second light chain, and a sixth 10 expression cassette encoding the second light chain, wherein the first heavy chain comprises from N- to C-terminus a first heavy chain variable domain, a CH1 domain, a first light chain variable domain, a CH1 domain, a hinge region, a CH2 domain and a CH3 domain, the second heavy chain comprises from N- to C-terminus the first heavy chain variable domain, a CH1 domain, a hinge region, a CH2 domain and a 15 CH3 domain, the first light chain comprises from N- to C-terminus a second heavy chain variable domain and a CL domain, and the second light chain comprises from N- to C- terminus a second light chain variable domain and a CL domain, wherein the first heavy chain variable domain and the second light chain variable domain form a first binding site and the second heavy chain variable domain and the first 20 light chain variable domain form a second binding site.