baber/WOPTO huggingface dataset:
Patent CZ-302870-B6 (CZ)
Title: Polynucleotide, polypeptide, pharmaceutical composition, vaccine and their use for the treatment and prevention of tuberculosis infection
Inventor: SKEIKY YASIR A W
IPC: A61P31/04
Filed: 1999-04-07
Abstract: The present invention relates to a polynucleotide comprising a first nucleotide sequence, which hybridizes under slightly stringent conditions with a second nucleotide sequence being complementary to a third nucleotide sequence, which encodes an amino acid sequence defined in the Claim No. 1, wherein said first nucleotide sequence encodes a polypeptide that is capable of inducing immunogenic response to TbRa12, TbH9 and TbRa35 in the T cell proliferation test, or in interferon gamma production test, or it hybridizes under slightly stringent conditions with the second nucleotide sequence being complementary to the third nucleotide sequence, which encodes the amino acid sequence defined in the Claim No. 1, wherein said first nucleotide sequence encodes a polypeptide that is capable of inducing immunogenic response to TbRa12, TbH9 and TbRa35 in the T cell proliferation test, or in interferon gamma production test. The invention also relates to a polypeptide encoded by said polynucleotide, as well as to a pharmaceutical composition and a vaccine containing said polynucleotide or polypeptide, and to their use in the treatment and prevention of tuberculosis infection.
Patent CZ-300910-B6 (CZ)
Title: Pharmaceutical formulation
Inventor: MCNAMARA DANIEL PATRICK
IPC: A61K9/00
Filed: 1999-06-08
Abstract: The present invention relates to new pharmaceutical formulation for aerosols with at least two or more active substances for administration by inhalation or by nasal route. Specifically, the invention relates to pharmaceutical preparations for propellant-driven metered dose aerosols using a fluorohydrocarbon as propellant, which contain a combination of active substance of two or more active substances, wherein at least one active substance being selected from the group consisting of ipratropium bromide, fenoterol and its salts, is present in dissolved form together with at least one other active substance in the form of suspended particles being selected from the group consisting of salbutamol or albuterol, cromoglycinic acid ant salt of these compounds.
Patent CZ-299201-B6 (CZ)
Title: Process for preparing N-(4,5-bis-methanesulfonyl-2-methylbenzoyl)guanidine hydrochloride
Inventor: GERICKE ROLF
IPC: C07C315/00
Filed: 2000-10-11
Abstract: N-(4,5-bis-methanesulfonyl-2-methylbenzoyl)guanidine hydrochloride of the general formula I, in which Me represents a methyl group and hydrochloride hydrate thereof is prepared so that first by conversion of the starting compound of the general formula II wherein Me denotes a methyl group and Q is a fluorine or chlorine atom to a nucleophilic substitution on an activated aromatic with a methane sulfinate the 4-methane sulfonyl group is introduced in a single-step reaction, then in the second step the compound of the general formula III is converted to acid chloride and is brought into reaction with guanidine to obtain N-(4,5-bis-methanesulfonyl-2-methylbenzoyl)guanidine and in the third step a hydrochloride of the general formula I is obtained by reacting the compound obtained of the previous step with aqueous hydrochloric acid and/or the compound is converted to hydrochloride hydrate.
Patent CZ-300616-B6 (CZ)
Title: Pharmaceutical composition
Inventor: FOGUET RAFAEL
IPC: C07H19/10
Filed: 2001-03-13
Abstract: The present invention describes the use of CDP-choline or pharmaceutically acceptable salts thereof for the manufacture of a pharmaceutical composition for the prophylactic treatment of cerebral ischemia whereby the CDP-choline or a pharmaceutically acceptable salt thereof is administered to patients who are at high risk of suffering an acute ischemic event prior the beginning of an ischemic episode where the acute ischemic event is represented by stroke due to several known risk factors, such as a history of previous transient ischemic episodes, arterial hypertension, hypercholesterolemia, smoking, auricular fibrillation or other embolic heart disease.
Patent CZ-299708-B6 (CZ)
Title: Mercaptoacetylamide derivatives, process of their preparation, pharmaceutical compositions in which the derivatives are comprised and intended for treating cardiovascular diseases
Inventor: FLYNN GARY A
IPC: A61P43/00
Filed: 2002-04-03
Abstract: The present invention relates to mercaptoacetylamide derivatives of the general formula I, and to pharmaceutical compositions incorporating these compounds and processes for preparing said compounds. Also disclosed is the use of said compounds for inhibition of the enzymes angiotensin converting enzyme and neutral endopeptidase, and for the treatment of cardiovascular diseases such as hypertension and congestive heart failure.
Patent CZ-299631-B6 (CZ)
Title: Feeding mechanism, particularly for feed carriage arranged on a giant machine tool cross rail such as turning and boring lathe
Inventor: MAREK JIRI
IPC: B23Q5/00
Filed: 2004-11-08
Abstract: In the present invention, there is disclosed a feeding mechanism consisting of a driving gear connected to a nut-like bush (8) being rotatably mounted within cylindrical cavity of a slide (3) body (10) and being fixedly coupled with a ball nut (7) arranged on a threaded shaft (6), and a brake for quick stoppage. A brake fixed part (14) is fastened in the cylindrical cavity of a slide (3) body (10) and a brake sliding part (13) encompassing the threaded shaft (6) and intended for stopping the nut-like bush (8) is arranged in said brake fixed part (14). The threaded shaft (6) being stationary mounted longitudinally in a cross rail (2) is supported by at least two sliding supports (16) arranged on the cross rail (2). The driving gear is provided with a failure sensor connected to control elements of the brake sliding part (13). The brake is represented by a hydraulically controlled cone brake the sliding part (13) of which is provided with a conical hole (18). The nut-like bush (8) is provided with a tapered termination (17) turned towards said conical hole (18). The threaded shaft (6) is arranged in said sliding supports (16) within eccentric bushings (25). The sliding supports (16) being mounted on linear guides (22) fastened in the cross rail (2) body are interconnected by pull rods (23).
Patent SK-287340-B6 (SK)
Title: Device for controlling the gas pressure in a coke oven chamber
Inventor: KREBBER FRANK
IPC: C10B27/06
Filed: 2002-03-23
Abstract: In the present invention, there is disclosed a device for controlling gas pressure within coke chamber of a coke furnace comprising an submersible bowl (4) in which water is supplied, and an submersible tube (6) that is connected with a coke chamber (1) gas space and ends in said submersible bowl (4). The submersible bowl (4) has an overflow (8) and a closable outlet (9). The submersible tube (6) has an end portion (10) the free cross section of which for gas discharge is dependent on a level (11) of liquid in the submersible bowl v (4). A water discharge tube (13) serves for controlling the liquid level (11). Said water discharge tube (13) inlet end reaches in the submersible tube (6), and the tube (13) has in its jacket inlet apertures (14) for water supply.; A slide valve (15), being arranged inside the discharge tube (13) and open on its front and rear faces closes, in dependence on its position in longitudinal direction, said discharge tube (13) inlet apertures (14), and forms a vertically adjustable overflow for water flowing in the water discharge tube (13). The discharge tube (13) inlet end is encircled by a siphon pipe (16) closing said discharge tube (13) on upper side, and forming a ring-shaped channel for water supply in the submersible bowl (4) below the submersible tube (6).
Patent BR-PI0317717-B8 (BR)
Title: composto, composição farmacêutica, e uso de um composto
Inventor: ANDREW AUSTEN MORTLOCK
IPC: C07D403/12
Filed: 2003-12-22
Abstract: composto, composição farmacêutica, uso de um composto, método para tratar um humano sofrendo de uma doença, e, processo para a preparação de um composto. derivados de quinazolina de fórmula(i), em que a é hereroarila de 5-membros, contendo um átomo de nitrogênio e um ou dois átomos de nitrogênio adicionais; composições contendo-os, processos para sua preparação e seu uso em terapia.
Patent BR-PI9917718-B8 (BR)
Title: bactéria pertencente ao gênero escherichia e tendo uma capacidade para produzir um l-aminoácido selecionado do grupo que consiste de ácido l-glutâmico, l-histidina, l-prolina e l-treonina, e, processo para produzir um l-aminoácido selecionado do grupo que consiste de ácido l-glutâmico, l-histidina, l-prolina e l-treonina.
Inventor: TOKHMAKOVA IRINA LYVOVNA
IPC: C12N1/21
Filed: 1999-12-28
Abstract: uma bactéria pertencente ao gênero escherichia e que tem uma capacidade para produzir um l-aminoácido, em que a capacidade para produzir o l-aminoácido é aumentada aumentando-se uma quantidade de expressão de pelo menos uma proteína de excreçâo de l-aminoácido e um processo para produzir l-aminoácido usando a bactéria.
Patent AT-504337-B8 (AT)
Inventor: CALLENBERG JONAS
IPC: F21W101/10
Filed: 2006-12-05
Granted: 2008-09-15
Abstract: Holder (HAL) comprises a holding clip (KLA) having two sides (SC1, SC2) elastically connected together and/or having at least one side elastic in sections so that the sides can be moved relative to each other and one each other. The sides slide in first guides (FU1, FU1') on a light source holding element (AUE) in a plane running parallel to a stopping surface (ANF) of the light source (LIQ) and in the longitudinal direction of the sides. Preferred Features: The holding clip is mounted on a receiving element in the direction of the receiving element with tensioning of the two sides. The two sides have a bend directed toward the receiving element in a pressing region (ANP1, ANP2).
Patent EP-1256880-B8 (EP)
Inventor: ROSAY ARNAUD
IPC: G06F13/16
Filed: 2002-05-03
Granted: 2011-03-23
Abstract: Data processing system including a processor (100), data memory (132), program memory (134) and principal bus (110) common to data and program memories and connecting them to the processor. The system includes a distribution interface (120) between the principal bus (110) and the memories to alternatively put then in communication, via the principal bus, in an 'active' access mode and to maintain the other memory in 'passive' access mode authorizing subsequent rapid access. The distribution interface includes a copier (122) for transferring signals between the principal bus (110) and a first secondary bus (140) connecting the interface to the data memory, and a second secondary bus (150) connecting the interface to the program memory. The interface includes a memory (125) to conserve the logic state of a signal applied to a memory at the moment of its passage from an active access mode, when it is communication with the processor, to a passive access mode. The principal bus includes a data bus (112), an address bus (114), a control bus (116) and an access indication bus (118).
Patent EP-1456071-B8 (EP)
Inventor: FRAISSE EMMANUELLE
IPC: B60T17/06
Filed: 2002-10-23
Granted: 2010-06-02
Abstract: A tank according to the invention comprises a casing, a filling port (5) extending, on the outside of said tank, into a filling neck (7), which is provided with a screw thread having a pitch (p) and which cooperates with a cap (9). The inner surface of the cap cooperating with the screw thread, at least one outlet port for the hydraulic-fluid flow towards a hydraulic circuit. Means (43) for the connection of the inner space (3) of the tank with the ambient air and comprising at least one transverse channel (45), more advantageously two channels (45), extending from a first lengthwise end (47) of the filling neck (7) to a second lengthwise end (49) of the filling neck (7), between the filling neck (7) and the cap (9) so as to connect the inside of the tank with the ambient air.
Patent EP-1500491-B8 (EP)
Inventor: DABOUINEAU JOHANN
IPC: B32B27/08
Filed: 2004-07-08
Granted: 2006-06-28
Abstract: The multi-layer pipe consists of at least two layers: an inner layer of a cyclo-olefin and outer layer of polyphenylene sulfide with suitable pressure and temperature resistance. It can also have at least one intermediate layer of a thermoplastic material, that adheres to the inner and outer layers.
Patent EP-1689425-B8 (EP)
Inventor: POULIQUEN GAUTHIER
IPC: A61K47/42
Filed: 2004-11-19
Granted: 2010-02-17
Abstract: A liquid pharmaceutical formulation (I) for prolonged release of active agent(s) (A) comprises a low viscosity aqueous colloidal suspension of submicron particles of water-soluble, biodegradable polymers (II) carrying hydrophobic groups, non-covalently associated with (A), where on parenteral injection (I) forms a gelled depot for prolonging the duration of (A) release to more than 24 hours. A liquid pharmaceutical formulation (I) for prolonged release of active agent(s) (A) comprises a low viscosity aqueous colloidal suspension (with water as dispersion medium) based on submicron particles (SMP's) of water-soluble, biodegradable polymers (II) carrying hydrophobic groups (HG's), non-covalently associated with (A). On parenteral injection, (I) forms a gelled depot in vivo (at least partially due to physiological proteins), controlling and prolonging the duration of (A) release to more than 24 hours. (I) is liquid under the injection conditions; at physiological temperature and/or pH; and/or in presence of physiological electrolytes at physiological concentrations and/or surfactant(s). Independent claims are included for: (1) a variant of (I) as described above, where the duration of release of (A) is not restricted but the concentration of (II) is sufficiently high to form a gelled depot in vivo in presence of protein(s) after parenteral injection; (2) novel derived products (preferably in powder or gel form), consisting of SMP's formed by non-covalent association of (II) and (A) as above and obtained from (I); and (3) methods of preparation of (I).
Patent EP-1725536-B8 (EP)
Inventor: LANGE JOSEPHUS H M
IPC: C07D233/28
Filed: 2005-02-16
Granted: 2009-04-22
Abstract: The present invention relates to 1,2,4-tri-substituted imidazoline derivatives, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazoline derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these imidazoline derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.
Patent EP-2273300-B8 (EP)
Inventor: STELZER ERNST
IPC: G02B21/16
Filed: 2003-06-06
Granted: 2021-03-31
Abstract: Microscope (100) with at least one illumination beam path (2) and at least one detection beam path (5) comprises a focussing arrangement (3) for each illumination beam path for producing an extended planar object illumination region in the direction of and perpendicular to an illumination axis of the illumination beam path. A detection device (10) of the detection beam path is arranged approximately orthogonally to the planar object illumination region. A movement arrangement is provided for producing relative movement between the planar object illumination region and an object (4) to be investigated. Independent claims are also included for alternative microscopes.
Patent BR-PI0711931-B8 (BR)
Inventor: SALZINGER JOSEF
IPC: C01B32/942
Filed: 2007-05-16
Abstract: Disclosed is the use of residual matter and/or waste as useful materials in electric low-shaft furnaces, said residual matter and/or waste being utilized for heating and/or as a carbon source. The low-shaft furnace used generally comprises a cover as well as at least one hollow electrode for introducing the starting materials. The residual matter and/or waste can be trash, industrial residues, or organic residue and refuse that is difficult to dispose of, such as medicaments, electronic scrap, high-calorie materials, and/or materials that pose a health hazard and can be halogenated. Said residual matter and/or waste preferably has a maximum particle diameter of 100 mm and is introduced particularly in a compact or extruded form into the furnace bed via the hollow electrode. Up to 95 percent of the residual matter and/or waste are converted into pyrolysis gases at furnace temperatures ranging from 1700 to 2500<SUP>o</SUP>C, and the obtained carbon is used as a carbon source, thus making it possible to significantly reduce the amount of energy required for producing calcium carbide, ferrosilicon, ferrochromium, etc.
Patent BR-PI0715396-B8 (BR)
Title: método de produção de uma composição para vacina
Inventor: JOHN J MEKALANOS
IPC: A61K39/00
Filed: 2007-08-07
Abstract: composição para vacina de matriz protéica, método de produção da referida composição, e uso da mesma. a presente invenção refere-se a composições para vacina que possuem uma proteína transportadora e um antígeno de interesse capturados em um complexo, a processos de produção de tais vacinas e a processos de administração de vacina.
Patent BR-PI0906298-B8 (BR)
Title: artigo absorvente descartável do vestuário
Inventor: KYOTA SAITO
IPC: A61F13/15
Filed: 2009-02-18
Abstract: artigo absorvente descartável do vestuário. um artigo absorvente descartável do vestuário compreende um chassi absorvente (11) e um almofadado elástico anular de cintura (12) onde um almofadado elástico de cintura (12) consiste de um almofadado frontal de cintura (12a) e um almofadado traseiro de cintura (12b). um almofadado traseiro de cintura (12b) possui uma dimensão na direção longitudinal maior do que aquela do almofadado frontal de cintura (12a) e compreende uma região elástica (45), uma região elástica (46) definindo uma faixa de cintura e uma região elástica (47) localizada à parte em direção à região entrepernas. um tensão elástica da região elástica 47 quando medida na direção transversa é definida para ser inferior àquela das regiões elásticas (45, 46).
Patent BR-PI0921339-B8 (BR)
Title: sistema de bolsa de sangue e cassete
Inventor: MAKOTO HIRABUKI
IPC: A61M1/36
Filed: 2009-11-18
Abstract: sistema de bolsa de sangue e cassete. a presente invenção refere-se a um sistema de bolsa de sangue (10a) que inclui uma bolsa de coleta de bc (54) para centrifugação de uma camada leuco plaquetária, um filtro (56) para remoção de células sanguíneas brancas de um líquido sobrenadante transferido da bolsa de coleta de bc (54), uma bolsa de coleta de plaqueta (58) para coletar o líquido sobrenadante que passou através do filtro (56), um primeiro tubo (60) que se conecta à bolsa de coleta de bc (54) e uma entrada (56a) do filtro (56), um segundo tubo (62) que se conecta à bolsa de coleta de plaqueta (58) e uma saída (56b) do filtro (56) e um cassete (50a) a ser fixado no aparelho de centrifugação e separação. o primeiro tubo (60) e o segundo tubo (62) são dispostos dentro do cassete (50a). o cassete (50a) inclui uma primeira seção de grampo (106) para fechamento e abertura do primeiro tubo (60) e segunda seção de grampo (108) para fechamento e abertura do segundo tubo (62).
Patent BR-112012020225-B8 (BR)
Title: Misturas de corantes reativo a fibras, e métodos para tingimento ou impressão tricromática
Inventor: ATHANASSIOS TZIKAS
IPC: C09B67/22
Filed: 2011-01-13
Abstract: MISTURAS DE CORANTES FIBRA-REATIVOS E SEU USO EM UM MÉTODO PARA TINGIMENTO OU IMPRESSÃO DI- OU TRI-CROMÁTICA. A presente invenção refere-se a misturas de corante compreendendo pelo menos um corante de tingimento vermelho da fórmula: (1) e pelo menos um corante de tingimento azul, amarelo, laranja ou marrom do grupo das fórmulas: (2), (4), (5) e (6), em que: B é um elemento de ligação em ponte alifático, R1, R3 e R8 são, cada um independentemente uns dos outros, hidrogênio ou C1-C4alquila, R2, R4, R5, R9, R11, R12, R13, R14, R15 e R16 são, cada um independentemente uns dos outros, hidrogênio, C1-C4alquila, C1-C4alcóxi ou sulfo, R6 e R10 são, cada um independentemente um do outro, amino ou C1-C4alquila, (R7)j denota substituintes j idênticos ou diferentes selecionados do grupo C2-C4alcanoilamino, ureido, C1-C4alquila e C1-C4alcóxi, (R17)i denota substituintes i idênticos ou diferentes selecionados do grupo C2-C4alcanoilamino, ureido, sulfato, C1-C4alquila e C1-C4 alcóxi, X1, X2, X3, X4, X5 e X6 são, cada um independentemente uns dos outros, halogênio, 3-carbóxipiridin-1-ila ou 3-carbamoilpiridin-1-ila, Z1, Z2 e Z3 são, cada um independentemente uns dos outros, um grupo fibra-reativo da fórmula: -SO2-Y8, (7a) ou -NH-CO-(CH2)2-3-SO2-Y9 (7b), Y1,Y2,Y3,Y4,Y5,Y6,Y7,Y8 e Y9 são, cada um independentemente uns dos outros, vinila ou um radical -CH2-CH2-U e U é um grupo removível sob condições alcalinas, i, j, k e I são, cada um independentemente um do outro, o número 0, 1 ou 2, m é o número 1 ou 2, n e u são, cada um independentemente um do outro, o número 1, 2 ou 3, p e q são, cada um independentemente um do outro, o número 0 ou 1, r e s são, cada um independentemente um do outro, o número 0 ou 1 e t é o número 0, 1 ou 2 e a soma de r, s e t é 2 ou 3 são adequados especialmente para o tingimento ou impressão dicromática ou tricromática de materiais de fibra celulósicos e proporcionam tingimentos ou impressões tendo boa reprodutibilidade e boas propriedades de solidez em geral.
Patent BR-112014027944-B8 (BR)
Title: Método para gerar um feixe de infravermelho para iluminar uma cena a ser imageada e aparelho para iluminar uma cena a ser imageada com radiação infravermelha
Inventor: COLIN JANSSEN
IPC: G08B13/181
Filed: 2013-01-28
Abstract: MÉTODO E APARELHO PARA ILUMINAR UMA CENA A SER IMAGEADA COM RADIAÇÃO INFRAVERMELHA E MÉTODO PARA GERAR UM MAPA DE COMPRIMENTO PERFIL-A-FOCAL DE FEIXE.  A presente invenção refere-se a um método para gerar um feixe de infravermelho (IR) para iluminar uma cena a ser imageada que compreende fornecer pelo menos dois emissores de IR (18(a),(b)), incluindo um primeiro emissor de IR (18(a)) operável para emitir um componente de feixe amplo do feixe de IR, e um segundo emissor de IR (18(b)) operável para emitir um componente de feixe estreito do feixe de IR, em que o componente de feixe amplo tem um perfil linear que tem um desvio padrão mais baixo do que um perfil linear do componente de feixe estreito. O método também compreende selecionar um perfil linear desejado para o feixe de IR, e selecionar uma razão de potência de potência direcionada para o primeiro emissor de IR (18(a)), e a potência direcionada para o segundo emissor de IR (18(b)) que produz o feixe de IR com o perfil linear desejado quando o componente de feixe estreito e o componente de feixe amplo forem combinados; e direcionar a potência para os primeiro e segundo emissores de IR (18(a),(b)) na razão de potência selecionada para gerar os componentes de feixe amplo e feixe estreito, e combinar os componentes de feixe amplo e feixe estreito gerados a fim de produzir o feixe de IR.
Patent BR-112014029701-B8 (BR)
Title: Processo para fabricação de polpa de dissolução, licor, e, polpa
Inventor: BORGARDS ANDREA
IPC: D21C3/02
Filed: 2013-05-28
Abstract: processo para fabricação de polpa de dissolução, licor, polpa, e, uso de uma polpa.  o presente documento se refere a processos para a fabricação de polpa e mais especificamente a processos melhorados para a fabricação de polpa de dissolução. os processos foram desenvolvidos primeiramente para serem usados em conexão com processos kraft de grande escala, isto é, eles foram projetados para serem incorporados dentro de uma instalação. um licor derivável do processo e compreendendo xilano, lignina, álcali e água é também descrito, assim como, uma polpa de dissolução produzida pelo processo.