baber/WOPTO huggingface dataset:
Patent ES-2174277-T3 (ES)
Title: Procedimiento de fabricacion de poliorganosiloxanos (pos) multifuncionales por deshidrogenocondensacion y hidrosililacion.
Inventor: PRIOU CHRISTIAN
IPC: C08G77/38
Filed: 1997-08-06
Granted: 2002-11-01
Abstract: LA PRESENTE INVENCION SE REFIERE A LA FABRICACION, A ESCALA INDUSTRIAL, DE POS MULTIFUNCIONALES. EL OBJETIVO DE LA INVENCION ES PERFECCIONAR EL PROCEDIMIENTO DE MULTIFUNCIONALIZACION DE POS DESCRITO EN LA WO 96/16 125 PARA HACER UN PROCEDIMIENTO INDUSTRIAL DE FABRICACION DE POS MULTIFUNCIONALES. ESTE OBJETIVO SE ALCANZA POR LA INVENCION QUE SE REFIERE A UN PROCEDIMIENTO DE FABRICACION (SEMI)CONTINUO DE POS CON FUNCIONALIDADES SI - ALQUILO Y SIOR (R = ALQUILO), EN EL QUE: 1. SE DELIMITA CONTINUAMENTE UN REACTOR A DE DESHIDROGENOCONDENSACION CON UN POS CON SIH, UN ALCOHOL ROH Y PLATINO; 2. SE EVACUA Y SE RECUPERA CONTINUAMENTE EL GAS FORMADO ELIMINANDO EL H 2 QUE CONTIENE Y RECICLANDO EL ROH POR CONDENSACION; 3. SE TRANSFIERE INMEDIATAMENTE EL POS CON SIH Y CON SIOR DERIVADO DE 1. EN UN REACTOR B DE HIDROSILILACION, PARA RECUPERAR FINALMENTE UN POS CON SI - ALQUILO Y CON SIOR. LA INVENCION SE REFIERE TAMBIEN A UN DISPOSITIVO PARA LA REALIZACION DE ESTE PROCEDIMIENTO. EL REACTOR DE ESTE DISPOSITIVO ES MULTIETAPICO. APLICACION: SINTESIS CONTINUA DE POS MULTIFUNCIONALES.
Patent ES-2189046-T3 (ES)
Title: Grifo de bola.
Inventor: WULLERICH MICHAEL
IPC: F16K35/02
Filed: 1998-07-25
Granted: 2003-07-01
Abstract: LA INVENCION SE REFIERE SE REFIERE A UNA VALVULA DE BOLA CON UNA CARCASA DENTRO DE LA CUAL ESTA DISPUESTO UN ELEMENTO DE CONMUTACION GIRATORIO ENTRE DOS POSICIONES EXTREMAS POR MEDIO DE UN EJE DE MANDO, PUDIENDO ACCIONARSE EL EJE DE MANDO POR MEDIO DE UNA PALANCA MANUAL, Y DONDE ESTA PREVISTO UN PESTILLO DESPLAZABLE A LO LARGO DE LA PALANCA MANUAL VENCIENDO LA FUERZA DE UN MUELLE DE RETENCION, Y QUE SE PUEDE ENCLAVAR EN VARIAS POSICIONES PREDETERMINADAS EN LA CARCASA.
Patent ES-2267160-T3 (ES)
Inventor: FALAVEGNA VALTER
IPC: B01D19/00
Filed: 1998-10-16
Granted: 2007-03-01
Abstract: A pump-breather unit (2) including a pump body (22) having a scroll or casing and a separator container (42) which includes a lower intake port (24) and an outlet port (27) not aligned with said intake port (24) and connected to pump intake, and a vent valve (26) at the top thereof. The scroll or casing (22), the separator container (42) and the vent valve (26) are monolithically integral with one another. A multi-layer grille (43) is provided in the separator container (42) designed to act as a trap for air bubbles that are present in the water fed into the separator container (42).
Patent ES-2174372-T3 (ES)
Title: Sistema de inyeccion de oxigeno caliente en un alto horno.
Inventor: RILEY MICHAEL FRANCIS
IPC: F27D17/00
Filed: 1998-10-27
Granted: 2002-11-01
Abstract: SE DESCRIBE UN PROCEDIMIENTO PARA PROPORCIONAR UNA CORRIENTE EN CHORRO EN UN ALTO HORNO, CARACTERIZADO PORQUE SE PROPORCIONAN AL AIRE DEL CHORRO COMBUSTIBLE Y OXIGENO CALIENTE, ENCONTRANDOSE EL OXIGENO CALIENTE A UNA TEMPERATURA Y VELOCIDAD SUPERIORES AMBAS A LA DEL AIRE DEL HORNO, Y CARACTERIZADO PORQUE EL COMBUSTIBLE Y EL OXIGENO CALIENTE EMPIEZAN LA COMBUSTION ANTES DE SU PASO AL ALTO HORNO A TRAVES DE LA CORRIENTE EN CHORRO.
Patent ES-2210667-T3 (ES)
Title: Acoplamiento ostomico.
Inventor: STEER PETER LESLIE
IPC: A61F5/448
Filed: 1998-01-15
Granted: 2004-07-01
Abstract: UN ACOPLAMIENTO PARA ORIFICIOS, POR EJEMPLO UN ACOPLAMIENTO PARA OSTOMIA, INCLUYE UNA PRIMERA PARTE (10) DE ACOPLAMIENTO FIJADA A UNA SEGUNDA PARTE (20) DE ACOPLAMIENTO MEDIANTE UN ANILLO (30) DE BLOQUEO, PARTIDO, RESILIENTE. EL ANILLO DE BLOQUEO (30) ES MANTENIDO CAUTIVO SOBRE EL PRIMER MIEMBRO (10) DE ACOPLAMIENTO POR UNAS OREJETAS (13) EXTENDIDAS RADIALMENTE DE LA PARTE EXTERNA DEL ANILLO DE BLOQUEO Y QUE PERMITEN AL ANILLO DE BLOQUEO (30) TRABAR AL SEGUNDO MIEMBRO (20) DE ACOPLAMIENTO DE FORMA SUSTANCIALMENTE CONTINUA ALREDEDOR DE LA PERIFERIA DEL SEGUNDO MIEMBRO DE ACOPLAMIENTO. EL ACOPLAMIENTO PODRA SER LIBERADO CUANDO LOS EXTREMOS (26, 27) DEL ANILLO DE BLOQUEO (30) SON MANIPULADOS PARA EXPANDIR EL ANILLO. EL ANILLO DE BLOQUEO (30) PODRA SER MOLDEADO INTEGRALMENTE CON EL PRIMER MIEMBRO DE ACOPLAMIENTO Y DOBLADO EN UNA POSICION OPERATIVA SOBRE EL PRIMER MIEMBRO DE ACOPLAMIENTO.
Patent ES-2238749-T3 (ES)
Inventor: WESTHOFF WILLIAM L
IPC: B32B5/26
Filed: 1998-04-16
Granted: 2005-09-01
Abstract: A belt reinforcing material of at least two layers where one layer is a twined fabric and the other layer is a woven fabric that are attached to each other such as by needle-punching. A toothed power transmission belt with a plurality of teeth spaced along one side of the belt includes the aforementioned fabric disposed at a peripheral surface that includes the belt teeth.
Patent ES-2209095-T3 (ES)
Inventor: SCHMED ARTHUR
IPC: A47J31/057
Filed: 1998-08-21
Granted: 2004-06-16
Abstract: The machine includes a unit for producing steam (B) which comprises a water supply container (10) which can be filled with fresh water. This unit can be independent of the arrangement for producing the brewing water (A) and can be formed as a closed circuit. The water supply container can be formed simultaneously as a steam separator and has a steam outlet (33). The steam producing unit can have a cross-sectional restriction (13) to ensure that when producing steam inside the water supply container an excess pressure prevails.
Patent ES-2246072-T3 (ES)
Inventor: SINACKEVICH NICKOLAI V
IPC: A61P25/28
Filed: 1998-08-06
Granted: 2006-02-01
Abstract: This invention concerns methods for prophylactic and therapeutic treatment of diseases responsive to the opening of potassium channels, peptides having potassium channel opener activities, and pharmaceutical compositions and kits comprising such peptides.
Patent ES-2221221-T3 (ES)
Inventor: JAKKULA JUHA
IPC: F23C10/02
Filed: 1998-11-17
Granted: 2004-12-16
Abstract: The invention relates to a method of separating solids from a gas flow in a fluidized catalytic process and to a cyclone assembly suited for use in a fluidized catalytic process. According to the invention, the gas flow of the process carrying the suspended solids is passed into a separation assembly, wherein the solids are separated from the gaseous phase under the effect of the centrifugal force, whereby a multiport cyclone is used as the separation assembly, into which the gas flow to be treated is passed via an inlet nozzle having an axially annular cross section. The use of the multiport cyclone, e.g., in an FCC process gives significant advantages in flow dynamics and process engineering over conventional arrangements and generally used single-port cyclones.
Patent ES-2210884-T3 (ES)
Title: Compresor de tornillo.
Inventor: HIDA TAKESHI
IPC: F04C29/12
Filed: 1999-04-08
Granted: 2004-07-01
Abstract: SE EFECTUA LA SEPARACION DE ACEITE DEL GAS DE DESCARGA DE UN COMPRESOR DE TORNILLO (6) CON UN SEPARADOR DE PARTICULAS (5) DISPUESTO EN LA CAMARA DE DESCARGA. PARA RESOLVER LA FALTA DE UNIFORMIDAD DE LA VELOCIDAD DE DISTRIBUCION DEL GAS EN LA CAMARA, SE DISPONE AL MENOS UN SEPARADOR DE PARTICULAS AUXILIAR (21) PARA SEPARAR EL ACEITE EN UN POSICION LOCAL INMEDIATAMENTE DETRAS O CERCA DEL LADO A FAVOR DE LA CORRIENTE DE UNA SALIDA DE UN CONDUCTO DE DESCARGA (15) EN UNA CAJA DE DESCARGA (3) PARA QUE QUEDE PERPENDICULAR A LA DIRECCION DEL FLUJO DEL GAS EN LA SALIDA. ADEMAS, SE DISPONE AL MENOS UNA PLACA OBSTACULIZADORA (22) EN EL LADO A FAVOR DE LA CORRIENTE DEL SEPARADOR DE PARTICULAS (5).
Patent ES-2241219-T3 (ES)
Title: Nuevo polisacarido inmunoestimulante procedente de la cepa de la especie phellinus, y su uso.
Inventor: YOO ICK-DONG
IPC: A61P35/00
Filed: 1999-10-18
Granted: 2005-10-16
Abstract: Es un objeto de la presente invención proporcionar una cepa de la especie Phellinus que produce un nuevo polisacárido de actividad inmunoestimulante. Es otro objeto de la presente invención proporcionar un nuevo polisacárido que muestra una potente actividad inmunoestimulante frente a enfermedades relacionadas con el sistema inmunitario. Es un objeto adicional de la presente invención proporcionar el uso del polisacárido como un agente de inmunoterapia o en el estudio del mecanismo básico de las enfermedades. Para lograr estos objetos, primeramente se cultivaron diversas cepas de la especie Phellinus, y se les aisló el ADN total mediante un método de SDS-fenol. Del ADN total, sólo se obtuvo el ADN mitocondrial. El ADN mitocondrial se digirió con enzimas de restricción BamHI, ClaI, EcoRI y PvuII, seguido de la electroforesis en un gel de agarosa. La filogenia de ADN, entre las cepas de Phellinus, se analizó según el método de Nei y Li (1979). A partir de los datos analíticos se encontró unanueva cepa que forma una nueva filogenia con otras cepas. Esta cepa se denominó Phellinus linteus Yoo, y se depositó en la Colección Coreana para Cultivos Tipo, Korean Research Institute of Bioscience and Biotechnology, el 17 de Noviembre de 1997 (número de depósito KCTC 0399BP). Se realizó una investigación de las características microbiológicas de la cepa KCTC 0399BP. Se aisló un nuevo polisacárido, y se purificó a partir de los cuerpos fructíferos y de los micelios de la nueva cepa, y se estudió para determinar la actividad inmunoestimulante. El polisacárido inmunoestimulante se analizó para determinar sus unidades de azúcares y su composición, seguido del análisis estructural del componente de hidratos de carbono. De forma similar, para comparación, se cultivaron otras diversas cepas de la especie Phellinus, y sus cuerpos fructíferos y micelios se sometieron a aislamiento y purificación para dar polisacáridos que también tenían actividad inmunoestimulante.
Patent ES-2187116-T3 (ES)
Inventor: VERMAAS DIRK JAN
IPC: C07H3/04
Filed: 1999-08-09
Granted: 2003-05-16
Abstract: The invention relates to a process for the selective oxidation of primary alcohols of oligosaccharides to form the corresponding carboxylic acid derivatives of the alcohols using catalytic amounts of a di-tertiary-alkyl nitroxyl free radical, characterized in that 1,3-dibromo-5,5-dimethylhydantoin or 1,3-dichloro-5,5-dimethylhydantoin is used as oxidant and the reaction is performed in neutral to basic conditions at a pH < 10. The process of the invention is useful for the production of (partially protected) oligosaccharides comprising carboxylate groups, both intermediates and end products.
Patent ES-2262297-T3 (ES)
Title: Proceso de direccionamiento para almacenamiento en memoria de bloques de imagen.
Inventor: SORIN ALAIN
IPC: G06F12/02
Filed: 1999-12-10
Granted: 2006-11-16
Abstract: Proceso para almacenar los datos de vídeo digital de una imagen, dividiéndose la imagen en primeros bloques de imagen (h, v) (1, 2) consistentes en v líneas de h puntos de imagen, constituyendo una fila el conjunto de bloques sobre una anchura de imagen, siendo almacenado los datos como bloques de imagen sucesivos (3, 13) en páginas sucesivas (4, 5, 6, 8) de una memoria dinámica de acceso aleatorio siguiendo un orden correspondiente a un barrido de tipo televisivo para lectura de segundos bloques de imágenes (H, V) (9, 10, 11) consistentes en V líneas de H puntos de imagen, caracterizado porque considerando la posición de los bloques en la imagen y la de las páginas que los contienen, el desplazamiento horizontal Dl.l+a en términos de número de primeros bloques (h, v) del límite de una página correspondiente a una fila I de la imagen respecto del límite de una página correspondiente a una fila I + a es igual a: Dl, l+aç = a D, siendo ¿a¿ un número entero positivo, menor que RM = INT [(V-2)/v] + 2, H (correspondiendo INT a la parte entera de la división) el valor D, que corresponde al desplazamiento entre dos filas sucesivas se selecciona de forma que: D> (BM-1), siendo BM = INT [(H-2)/h] + 2
Patent ES-2204102-T3 (ES)
Inventor: SAWATZKI HARRY
IPC: B05C11/10
Filed: 1999-01-19
Granted: 2004-04-16
Abstract: Device for coating disks (3), particularly optically readable data carriers, with a holding device (2) for holding a disk to be coated (3), an annular nozzle unit (8) for the application of coating liquid to the disk (3) and a collection zone (7). The coating liquid is applied continuously from the nozzle unit (8) and reaches the collection zone (7) via an annular wetting zone (15), being returned from the collection zone (7) to the nozzle unit (8) via a storage tank (19). The movement unit (6) permits the disk (3) to be brought concentrically into contact with the wetting zone (15) and again removed from it. A ring (16) of coating liquid remains on the disk (3) as a result of adhesive forces. This ring (16) is uniformly distributed over the disk, for example, by means of a centrifuge. The continuous flow of coating liquid permits a constant viscosity of the coating liquid to be achieved. Those problems which can occur with straight-line application are avoided. Moreover, the design of the coating device is simple.
Patent ES-2277436-T3 (ES)
Inventor: DE CLERC J
IPC: F23L15/02
Filed: 1999-05-18
Granted: 2007-07-01
Abstract: Anti-leak two-port and three-port poppet valves for a regenerative thermal oxidizer in which a gas such as contaminated air is first passed through a hot heat-exchange bed and into a communicating high temperature oxidation (combustion) chamber or zone, and then through a relatively cool second heat exchange bed. The alternating of the heat transfer zones to provide matrix regeneration is accomplished via regenerative thermal oxidizer switching valves. In the preferred embodiment of the present invention, the switching valves are horizontal pneumatic poppet type valves in a consolidated housing, the valve's switching frequency or cycle being a function of volumetric flow rate.
Patent ES-2272070-T3 (ES)
Inventor: KOTTWITZ BEATRIX
IPC: C11D3/04
Filed: 1999-05-25
Granted: 2007-04-16
Abstract: Detergent characterized in that it contains  alpha -amylase from Bacillus amyloliquefaciens and an alkaline percarbonate, in addition to other usual ingredients compatible with said constituents.
Patent ES-2217783-T3 (ES)
Inventor: BOSTROM JAN-OVE
IPC: C08L23/04
Filed: 1999-07-01
Granted: 2004-11-01
Abstract: A composition for an insulating layer of an electric cable wherein the composition contains an ethylene plastic as the base resin and further contains up to about 5% by weight of additives including antioxidant, and peroxide cross-linking agent. The composition is characterised in that the antioxidant additive includes a compound of the formula (V): R1(-(C+O)O-)k(CH2)1-S-(CH2)m(-OO(C=O)-)nR2 where R1 and R2, which are the same of different, are C7-C23 alkyl, C7-C23 alkenyl, R3-Ar-, Ar-R3-, or AR-, where R3 is C8-C24 alkyl and Ar is c6-c14 aryl; k and n, which are the same of different, are 0 or 1, l and m, which are the same or different, are integers >=0; with the proviso that the compound is free from phenolic groups; and that the compositions is free from compounds having the formula (VI): R-O-(C=O)-CH2CH2SCH2CH2-(C=O)-O-R where R is a C8-C20 alkyl group.
Patent ES-2204151-T3 (ES)
Inventor: FIELDS BRIAN
IPC: B21D51/30
Filed: 1999-08-19
Granted: 2004-04-16
Abstract: A method and apparatus for seaming a can end to a can body and a can made thereby. The can end has a side wall forming an angle in the range of about 12 DEG  to 15 DEG . A seaming chuck is inserted into the can end adjacent its side wall. The seaming chuck has upper and lower walls. The upper wall is essentially cylindrical or slightly negatively tapered. The lower wall is disposed at an angle very close to that of the can end side wall so that the upper and lower chuck side walls form an obtuse angle in the range of about 162 DEG  to 168 DEG . A can seamed using such a chuck will have a segmented, kinked side wall comprising upper and lower substantially straight sections intersecting at a circumferentially extending crease and forming an obtuse angle.
Patent ES-2260939-T3 (ES)
Title: Proyectiles no letales.
Inventor: SAXBY MICHAEL ERNEST
IPC: F42B12/34
Filed: 1999-10-26
Granted: 2006-11-01
Abstract: Una combinación de una pistola que tiene un cañón y medios de propulsión para lanzar un proyectil del cañón; y un proyectil no letal (14); donde el proyectil no letal (14) consta de una caja exterior esférica hueca (20) formada por un material elásticamente deformable, y un conjunto de bolas sustancialmente esféricas (22) que están dentro de la caja, en uso, la caja exterior esférica (20) se deforma cuando viaja a lo largo del cañón de fusil bajo la presión de los medios de propulsión pero siendo lo suficientemente elástica para moldearse a un estado no deformado tras abandonar el cañón de fusil y caracterizado por el hecho de que las bolas sustancialmente esféricas (22) están formadas por un material que tiene una densidad mayor que el material elásticamente deformable que forma la caja exterior esférica y tiene un diámetro máximo en un intervalo de 2 mm a 10 mm, una densidad mínima equivalente a una gravedad específica de 7.0 y una mínima dureza Rockwell de 90.5 y donde el conjunto de bolas sustancialmente esféricas (22) tienen superficies lisas para permitir que las bolas individuales se deslicen fácilmente sobre las superficies de otras.
Patent ES-2180335-T3 (ES)
Inventor: KNOCHEL PAUL
IPC: C07C69/34
Filed: 1999-11-12
Granted: 2003-02-01
Abstract: A ferroceneylphosphine ligand and complexes prepared therefrom for homogeneous catalytic enantioselective hydrogenation, the ligand having the formula (I):Another aspect of the invention is directed to a ferroceneylphosphine ligand of formula (II),
Patent ES-2323991-T3 (ES)
Inventor: ZHANG SHUYUAN
IPC: A61K35/761
Filed: 1999-11-16
Granted: 2009-07-28
Abstract: The present invention addresses the need to improve the long-term storage stability (i.e. infectivity) of vector formulations. In particular, it has been demonstrated that for adenovirus, the use of bulking agents, cryoprotectants and lyoprotectants imparts desired properties that allow both lyophilized and liquid adenovirus formulations to be stored at 4°C for up to 6 months and retain an infectivity between 60-100% of the starting infectivity.
Patent ES-2339309-T3 (ES)
Inventor: JACQUIOD CATHERINE
IPC: B32B5/18
Filed: 1999-12-16
Granted: 2010-05-18
Abstract: The substrate of the invention is coated with a mesoporous film. It is characterized in that chemical molecules, especially hydrophobic/oleophobic molecules, are bonded to the mesoporous film. The invention also relates to a process for manufacturing this substrate, in which: the substrate is brought into contact with a composition formed from organic assembling groups and from a precursor for the mesoporous material; the precursor precipitates around the assembling groups and polymerizes; and the assembling groups are removed. This process is distinguished by the fact that chemical molecules, such as hydrophobic/oleophobic molecules, are then brought into contact with the mesoporous film. The invention also relates to glazing, for buildings or transportation vehicles, which includes this substrate.
Patent ES-2224753-T3 (ES)
Inventor: LINDVOLD LARS
IPC: G03H1/02
Filed: 1999-11-19
Granted: 2005-03-01
Abstract: The present invention relates in a broad aspect to a method and a device for applying structures to a medium being conveyed on a length. The method and device utilise a moulding process in which micro structures are moulded into/onto the surface of the medium. In a specific embodiment, the present invention relates to a process faciliting the replication of microstructures in a conventional printing machine. The replication method is integrated as a part of the machine, thus making it possible to perform the application of microstructures in-line. As the replication of the microstructure takes place in-line, the application of, e.g., holograms will be in register with the printed material.
Patent PL-1625081-T3 (PL)
Title: Holder for containers containing viscous products
Inventor: OMRCEN ZDRAVKO
IPC: B65D51/24
Filed: 2004-03-25
Abstract: A holder of containers containing viscous matters in two basic embodiments, one with a solid body and one with an at least partially hollow body. Each embodiment holder has an opening of a size to accommodate a neck of a container containing viscous liquids. In use, the neck is inserted within the opening such that the container is positioned upside down. The holder is either seated or affixed, such as by suction, to a base, thereby allowing the holder to hold the container upside down with the neck inserted into the holder opening. In the solid body embodiment, the body's wide lower portion and weight aid in keeping the holder seated relative to the base. In the hollow body embodiment, the holder has a wide opening at its bottom portion and a fitting to which a pneumatic sucker, or suction device, is fitted. The suction device fixes the holder to the base via a suction seal between the suction device and the base.
Patent PL-1767696-T3 (PL)
Title: Railway sleeper
Inventor: KIEFER BRUNO
IPC: E01B3/28
Filed: 2005-09-21
Abstract: Railway sleeper made of concrete comprises an elongated sleeper body (1) having two head parts (2) that have a rectangular horizontal projection with a width (B) corresponding to 13-20% of the length (A) of the sleeper body and a length (C) corresponding to 20-30 of the length of the sleeper body. An independent claim is also included for a railway track comprising railway sleepers separated by a distance corresponding to 130-155% of the width of the head parts. Preferred Features: The width of the head parts corresponds to 17-18 or 15-16 of the length of the sleeper body. The length of the head parts corresponds to 24-26 of the length of the sleeper body.
Patent PL-1880452-T3 (PL)
Title: A device for a remote monitoring the state of at least a single-pole surge protection
Inventor: CERNICKA JOZEF
IPC: H01C7/12
Filed: 2005-10-10
Abstract: The invention relates to a device for a remote monitoring the state of at least a single-pole surge protection which consists of a bracket (1) and at least one slide-in protective member (2) whereas the bracket (1) and also the slide-in protective members (2) are fitted with mechanical devices for detecting the status change of each of the slide-in protective members (2) and the bracket (1) is further fitted with devices for the status change of the switch (4) on the basis of a status change of some of the slide-in protective members (2) whereas the switch (4) is fitted with devices for connecting to the remote conduit of the status change of the switch (4) signal.
Patent PL-2010334-T3 (PL)
Title: Spray dispenser for use with compressed gas container
Inventor: LAWS KAREN
IPC: B67D99/00
Filed: 2007-03-22
Abstract: A dispenser (1) comprising a container (3) for the storage of a liquid, a gas cartridge receiving portion (5) for holding a gas cartridge so that the contents of the container may be pressurized by gas in a gas cartridge and a dispensing arrangement for dispensing the liquid as a spray, the dispensing arrangement comprising an actuator (8), an outlet (30) and a valve (22) operable by the actuator, in use, to control the release of the liquid from the outlet, wherein the dispenser comprises a tamper-evident member (15) indicative to a user of whether a gas cartridge has been moved into a pressurizing position.