baber/WOPTO huggingface dataset:
Patent CA-3104858-A1 (CA)
Title: Compositions and methods for the treatment of anesthesia-induced neurotoxicity
Inventor: MANSELL JOHN
IPC: A61K31/7088
Filed: 2019-06-28
Abstract: A formulation comprising an oligonucleotide selected from the group consisting of an oligonucleotide having one of SEQ ID No.:1 through SEQ ID No.:42 or a variant thereof. Also, a method of treating anesthesia-induced neurotoxicity. The method may comprise administering the formulation. The formulation may be administered prior to, concomitant with, subsequent to, or combinations thereof administration of a general anesthetic comprising a fluorinated compound. The oligonucleotide may be incorporated into a carrier system, for example, a liposome, a biodegradable polymer, a hydrogel, or a cyclodextrin, a nucleic acid complex, a virosome, or combinations thereof. Also, a method of treating anesthesia-induced neurotoxicity.
Patent CA-3106409-A1 (CA)
Title: Mobile ultrawideband radar for monitoring thoracic fluid levels and cardio-respiratory function
Inventor: ERTIN EMRE
IPC: A61B5/07
Filed: 2019-07-17
Abstract: Various examples related to mobile bodily monitoring using ultra-wideband radar are provided. In one example, a method for determining a bodily characteristic includes collecting sets of reflected backscatter data for a sequence of ultra-wideband (UWB) pulses transmitted via an UWB sensor, and a corresponding calibration measurement from a calibration channel; determining reflection coefficients for each tissue interface based on the sets of reflected backscatter data; and determining a fluid level content of the lung tissue based upon the reflection coefficients. The reflection coefficients can be determined from reflection profiles based upon the reflected backscatter data for that sequence of UWB pulses and the corresponding calibration measurement. The UWB sensor can include an array of transmit (TX) and receive (RX) antenna pairs positioned on a body of a user. The reflection profile can be associated with a model of tissue layers in the body between the UWB sensor and lung tissue.
Patent CA-3113657-A1 (CA)
Inventor: LOEIAN SEYED MASOUD
IPC: C12N5/078
Filed: 2019-09-20
Abstract: Methods and devices are provided for the detection and characterization of circulating cells in a blood sample. Such method can include depositing a sample of a bodily fluid on a device comprising carbon nanotubes, wherein the surfaces of the carbon nanotubes are not functionalized; and detecting target cells adhered to the carbon nanotubes.
Patent CA-3114177-A1 (CA)
Title: System and method for non-destructively normalizing loudness of audio signals within portable devices
Inventor: RIEDMILLER JEFFREY C
IPC: H03G7/00
Filed: 2011-02-03
Abstract: Many portable playback devices cannot decode and playback encoded audio content having wide bandwidth and wide dynamic range with consistent loudness and intelligibility unless the encoded audio content has been prepared specially for these devices. This problem can be overcome by including with the encoded content some metadata that specifies a suitable dynamic range compression profile by either absolute values or differential values relative to another known compression profile. A playback device may also adaptively apply gain and limiting to the playback audio. Implementations in encoders, in transcoders and in decoders are disclosed.
Patent CA-3118222-A1 (CA)
Inventor: APCHER SEBASTIEN
IPC: A61P35/04
Filed: 2019-11-15
Abstract: The present invention relates to the fields of medicine and in particular cancer treatment. The invention more specifically relates to new compounds which are typically for use as a medicament. In particular, the invention relates to the use of these new compounds for increasing the presentation, typically the production and presentation, of Pioneer Translation Products (PTPs)-derived antigens by cells, in particular cancer cells, or changing the immunopeptidome, in a subject, and inducing or stimulating an immune response in the subject. The present disclosure also relates to uses of such compounds, in particular to prepare a pharmaceutical composition and/or to allow or improve the efficiency of a therapy in a subject in need thereof. The invention also discloses methods for treating a disease, in particular cancer, for preventing or treating cancer metastasis and/or cancer recurrence, in a subject. The present invention in addition provides kits suitable for preparing a composition according to the present invention and/or for implementing the herein described methods.
Patent CA-3119817-A1 (CA)
Inventor: D'AGOSTINO DINO PAUL
IPC: G06Q20/10
Filed: 2021-05-27
Abstract: A computer-implemented method is disclosed. The method includes: receiving, via a client device, a request to configure a resource transfer of a first type; determining a first set of themes associated with resource transfers of the first type; and providing, for display on the client device, a user interface for configuring the resource transfer with theme data for a theme, wherein providing the user interface includes: displaying at least a subset of the first set of themes; receiving, via the client device, a selection of one of the themes of the displayed subset; obtaining an indication of available multimedia content items associated with the selected theme; and graphically presenting user interface elements corresponding to the multimedia content items via the user interface.
Patent CA-3120157-A1 (CA)
Title: Damping material as intermediate layer for a brake pad and process for making the damping material
Inventor: MUELLER GEORG
IPC: C08J3/20
Filed: 2021-05-14
Abstract: The present invention relates to a damping material 10 for a damping layer or interlayer of a brake lining which has at least one rubber content and one resin content.  A plurality of macroscopic, heterogeneously delimited areas are formed in the damping material 10, said areas comprising rubber areas 1 with a high rubber content of at least 3% to maximally 50% by weight, and resin areas 2 with a high resin content of at least 5% by weight, whereby the rubber areas 1 are free of resin, and the resin areas 2 are free of rubber, or the rubber areas 1 have a resin content <5% by weight.
Patent CA-3120983-A1 (CA)
Title: Fibrous structure products comprising layers each having different levels of cellulose nanoparticle
Inventor: ZIEGENBEIN TOBIAS
IPC: D21H27/30
Filed: 2019-11-26
Abstract: A fibrous structure having at least two layers is disclosed. Each of the at least two layers has a mixture of structural fibers selected from the group consisting of softwood fibers, non-wood fibers, natural non-cellulosic fibers, man-made cellulosic or non-cellulosic fibers, hardwood fibers, recycled fibers, and mixtures thereof. Each of the at least two layers are disposed in a face-to-face relationship. A second layer of the at least two layers has from about 0.05 percent to about 20 percent by weight of the second layer of cellulose nanoparticles.
Patent CA-3121653-A1 (CA)
Title: Computing environment system for monitoring aircraft engines
Inventor: LACAILLE JEROME HENRI NOEL
IPC: G05B23/02
Filed: 2019-12-05
Abstract: The invention relates to a computing environment system for monitoring aircraft engines, said system being connected to a cluster of servers, said system comprising: - an application interface (13) configured so as to receive user codes (19) that are developed independently from a distributed deployment system specifying the calculation of a set of indicators relating to an aircraft engine (3) for deployment on a fleet (12) of aircraft engines; - an extraction module (15) configured so as to extract said indicators by deploying parallel calculations on temporal flight data from the fleet of aircraft engines and stored in a database (9) distributed over said cluster (5) of servers (7); - a learning module (17) configured so as to use said indicators to construct, without supervision, from said indicators, a monitoring model (21) representative of the indicators by implementing predetermined learning functions.
Patent CA-3124257-A1 (CA)
Inventor: PULKIN MAXIM
IPC: C04B28/26
Filed: 2019-09-10
Abstract: The present invention relates to an inorganic binder system comprising blast furnace slag, and at least one solid alkali metal silicate, wherein the inorganic binder system is obtainable by co-grinding a mixture comprising the blast furnace slag and the at least one solid alkali metal silicate.
Patent CA-3126668-A1 (CA)
Title: Louvers, and wind turbines comprising such louvers
Inventor: RODRIGUEZ BAYO ROBERTO
IPC: F01P11/00
Filed: 2021-08-04
Abstract: The present disclosure relates to louvers for enabling an air passage between an outside and an inside. More particularly, the present disclosure relates to louvers enabling said air passage while minimizing rain ingress towards an interior and minimizing noise produced in the interior. The present disclosure further relates to wind turbines including said louvers.
Patent CA-3129999-A1 (CA)
Title: Electric fireplace integrated with a ductless heat pump head
Inventor: STOTT GRANT
IPC: F24D19/00
Filed: 2021-09-07
Abstract: The invention provides an integration of an electric fireplace or electric fireplace insert with a ductless heat pump system as an indoor heat pump head unit. The electric firebox is located in front of a set of heat exchanging fins through which refrigerant flows from an outdoor heat pump unit to provide heating in the summer and cooling in the winter. Air is pulled in from below the firebox, passes through the heat exchanging fins, and is exhausted above the firebox as conditioned air. The unit includes a filter at the air intake, an exhaust fan at the exhaust port for air circulation, and a condensate pump to provide the dehumidification aspects of the heat pump head.
Patent CA-3130785-A1 (CA)
Inventor: YACYSHYN VINCENT
IPC: C12N11/00
Filed: 2020-02-19
Abstract: Chaîne de production d'enzymes ayant une pluralité d'enzymes liées à un support pour exécuter une série de réactions catalysées pour convertir un substrat en un produit final. L'invention porte en outre sur un procédé d'utilisation de la chaîne de production d'enzymes pour former un produit final dans lequel un substrat entre en contact avec une première enzyme liée à un support pour former un intermédiaire et la mise en contact de l'intermédiaire avec une seconde enzyme liée à un support pour former un produit final.
Patent CA-3131013-A1 (CA)
Title: Manchon pour connecteur de cable coaxial avec decoupe
Inventor: WATKINS HAROLD J
IPC: H01R24/42
Filed: 2020-02-24
Abstract: L'invention concerne un manchon de couple comprenant un corps de manchon configuré pour s'étendre le long d'un axe. Le corps de manchon est en outre configuré pour recevoir au moins partiellement un élément de couplage d'un connecteur de câble coaxial. Le corps de manchon a une surface externe configurée pour permettre à un utilisateur de serrer l'élément de couplage sur un orifice d'interface jusqu'à un premier couple, et le corps de manchon comprend une paire de découpes opposées configurées pour recevoir un outil de serrage de façon à permettre à l'outil de serrage de saisir l'élément de couplage et serrer l'élément de couplage sur un orifice d'interface jusqu'à un second couple, le second couple étant supérieur au premier couple.
Patent CA-3131160-A1 (CA)
Inventor: SLAVCHEVA GABRIELA
IPC: G06F30/23
Filed: 2020-02-21
Abstract: This specification describes methods, systems and apparatus for simulating quantum optical systems. According to a first aspect of this disclosure, there is described a computer implemented method of simulating a quantum optical system, the method comprising: receiving properties of the quantum optical system; receiving properties of an electromagnetic pulse; determining a set of pseudospin equations based on the properties of the quantum optical system; determining initial values of electric field components and/or magnetic field components, and pseudospin components on a grid corresponding to a region of space comprising the optical system based on the pseudospin equations and the properties of the electromagnetic pulse; performing temporally shifted updating of the electric field components, the magnetic field components and the pseudospin components on the grid based on Maxwell's curl equations and the pseudospin equation to simulate time evolution of the quantum optical system under the electromagnetic pulse; wherein the grid comprises: a first set of grid points associated with the magnetic field components; a second set of grid points associated with the electric field and pseudospin components, wherein the second set of grid points is spatially offset from the first set of grid points.
Patent CA-3131907-A1 (CA)
Inventor: LIU ZHIPAN
IPC: G06F21/00
Filed: 2019-04-03
Abstract: User input is collected that is received by a client device, where the client device provides access to a remotely hosted application. The client device analyzes the collected user input received by the client device in order to detect collected user input indicative of machine behavior that simulates inputs provided by a user. The client device prevents subsequent access to the hosted application through the client device in response to detection of collected user input received by the client device indicative of machine behavior that simulates inputs provided by a user, in order to protect the remotely hosted application from malicious attacks.
Patent CA-3138401-A1 (CA)
Title: Methods of treating neuropathy
Inventor: BLANCHETOT CHRISTOPHE
IPC: A61P25/28
Filed: 2020-05-21
Abstract: The present invention relates to a method of treating a paraproteinemic neuropathy in a subject by administering to the subject an antagonist of the complement system. The antagonist inhibits the complement system upstream of complement factor C5. More specifically, the antagonist may be an antibody or an antigen-binding fragment thereof that blocks or inhibits the complement system by inhibiting the C2b domain of complement factor C2. The paraproteinemic neuropathies that may be treated include, in particular, multifocal motor neuropathy (MMN), chronic inflammatory demyelinating polyneuropathy (CIDP), and Guillain-Barré syndrome (GBS).
Patent CA-3139647-A1 (CA)
Inventor: SOLL HANS
IPC: A01K85/00
Filed: 2021-11-19
Abstract: The object of the present invention is a wobbler with adjustable gravity centre location having a hollow opening with a threaded sleeve in a casing containing a movable threaded exchangeable additional weight for changing the height of the location of gravity centre of the casing relative to its central axis.
Patent CA-3141824-A1 (CA)
Title: Helically baffled heat exchanger
Inventor: MACEDO ERIC DREW
IPC: F28D7/16
Filed: 2020-05-27
Abstract: A heat exchanger including a shell having a longitudinal axis, a plurality of baffles, such as elliptical sector- shaped baffles, each mounted in the shell at a helix angle HB to guide a fluid flow into a helical pattern through the shell. Each of the plurality of baffles includes an outer circumferential edge, a proximal radial edge, a distal radial edge, a proximal side, a distal side, and a plurality of spaced apart holes that are traversed by a plurality of axially extending tubes. Each of the first plurality of seal strips is disposed from a proximal of the plurality of baffles to a distal of the plurality of baffles.
Patent CA-3145275-A1 (CA)
Inventor: BRUCE JOHN A
IPC: H01S3/00
Filed: 2020-09-22
Abstract: A quantum data buffering system includes a data processor connected to a photon path quantum data buffer, a quantum mechanical elements source, a double slit filter, a non-linear optical crystal, a spontaneous parametric down converter and a Glan-Thompson prism. An output channel includes a data encoding sensor, qubits storage and single photon records storage. An input channel, includes a data decoding sensor and single photon records storage with path information.
Patent CA-3146921-A1 (CA)
Title: Hydraulic cylinder monitoring
Inventor: Smith John Forrest
IPC: F15B20/00
Filed: 2022-01-31
Abstract: A refuse collection vehicle has various hydraulic actuators including at least one cylinder with an internal seal. A sensor is responsive to movement of the piston and sends a signal to a controller to indicate piston movement information during an associated vehicle body component movement. The controller is configured to determine a motion characteristic of the piston during a predetermined body component movement, compare the determined motion characteristic to a stored reference motion characteristic, and in response to determining that a difference between the determined motion characteristic and the reference motion characteristic is greater than a predetermined value, trigger an indication that the refuse collection vehicle is in need of service.
Patent CA-3148726-A1 (CA)
Inventor: PICON RUIZ ARTZAI
IPC: A01M21/00
Filed: 2020-09-03
Abstract: L'invention concerne un procédé mis en uvre par ordinateur, un produit programme d'ordinateur et un système informatique (100) pour identifier des mauvaises herbes dans un champ de culture à l'aide d'un réseau neuronal convolutif à double tâche (120) ayant une topologie avec un module intermédiaire (121) pour exécuter une tâche de classification associée à une première fonction de perte (LF1), et avec un module de segmentation sémantique (122) pour exécuter une tâche de segmentation avec une seconde fonction de perte différente (LF2). Le module intermédiaire et le module de segmentation sont entraînés ensemble en tenant compte des première et seconde fonctions de perte (LF1, LF2). Le système exécute un procédé comprenant la réception d'une entrée d'essai (91) comprenant une image montrant des plantes cultivées d'une espèce de culture dans un champ agricole et montrant des mauvaises herbes d'une ou de plusieurs espèces de mauvaises herbes parmi lesdites plantes cultivées ; la prédiction de la présence d'une ou de plusieurs espèces de mauvaises herbes (11, 12, 13) qui sont présentes dans la tuile respective ; la délivrance en sortie d'une carte de caractéristiques intermédiaires correspondante au module de segmentation en tant que sortie de la tâche de classification ; la génération d'un masque pour chaque classe d'espèces de mauvaises herbes en tant que sortie de segmentation de la seconde tâche par extraction de caractéristiques à échelles multiples et d'informations de contexte à partir de la carte de caractéristiques intermédiaires et la concaténation des informations extraites pour effectuer une segmentation sémantique ; et la génération d'une image finale (92) indiquant pour chaque pixel s'il appartient à une espèce de mauvaises herbes particulière et, si tel est le cas, à quelle espèce de mauvaises herbes il appartient.
Patent CA-3150071-A1 (CA)
Title: Cell-surface receptors responsive to loss of heterozygosity
Inventor: KAMB CARL ALEXANDER
IPC: C12N5/00
Filed: 2020-08-06
Abstract: The disclosure relates to systems of two engineered receptors each having a ligand binding domain, collectively designed to target cells identified by loss of heterozygosity and used to treat a disease or disorder, for example, cancer. The disclosure provides immune cells expressing two engineered receptors, methods of making same, and polynucleotides and vectors encoding same.
Patent CA-3150200-A1 (CA)
Inventor: POTH LEISSNER F
IPC: B23P15/02
Filed: 2022-02-25
Abstract: A turbine blade includes a blade tip defining pressure side cooling apertures. The turbine blade defines a serpentine cooling passage having a first, second, and third legs, and first and second junction portions. The first leg extends radially and is connected to the second leg by the first junction portion proximate the blade tip. The second leg extends radially between the first and second junction portions. The second junction portion connects the second leg to the third leg which extends radially toward the blade tip and is connected to a trailing edge cooling aperture to exhaust the gas to an exterior of the turbine blade. The turbine blade defines a plenum connected to the first junction portion. At least one tip cooling aperture connects to the plenum and is radially outward of the third leg and axially aftward of at least a portion of the third leg.
Patent CA-3150462-A1 (CA)
Title: Anticorps anti-cd19 et leurs utilisations
Inventor: CHEN YAN
IPC: A61K39/00
Filed: 2020-08-19
Abstract: La présente invention concerne des anticorps anti-CD19 à haute affinité et des méthodes d'utilisation de ceux-ci à des fins thérapeutiques et/ou diagnostiques. L'invention concerne également des méthodes de production de tels anticorps anti-CD19. Les anticorps anti-CD19 selon l'invention ont montré une stabilité élevée telle que déterminée par des dosages par déplacement thermique et se lient à différents épitopes CD19 comme FMC63. L'invention concerne également le clone d'anticorps anti-CD19 utilisé pour développer des agents immunothérapeutiques tels que le tisagenlecleucel.
Patent CA-3150745-A1 (CA)
Inventor: KARLSON DALE
IPC: C12N15/63
Filed: 2020-08-14
Abstract: The present invention is directed to methods and compositions for breeding plants with an altered flavor or odor profile. Particularly, next generation plant breeding technologies are utilized for producing plants with target genes edited to reduce pungency in flavor or odor. The breeding method is capable of producing mustard plants in which the mustard bomb reaction is disarmed and/or plants with a reduced pungency and/or bitterness in flavor and/or odor.
Patent CA-3156240-A1 (CA)
Title: Systemes multi-livrables auto-microemulsifiants
Inventor: SHADE CHRISTOPHER W
IPC: A61K47/46
Filed: 2020-10-18
Abstract: Compositions sous la forme de solutions à base d'huile qui forment des microémulsions d'huile dans de l'eau (OIW) dans l'environnement aqueux du tractus gastro-intestinal lorsqu'elles sont administrées par voie orale par l'intermédiaire d'une capsule dure ou molle. Les microémulsions résultantes qui se forment à partir de la solution à base d'huile à l'intérieur su tractus gastro-intestinal peuvent libérer rapidement des espèces solubles dans l'huile et des espèces solubles dans l'alcool (y compris des espèces solubles dans l'alcool assistées par un dérivé de PEG) livrables à la circulation sanguine à travers les tissus formant le tractus gastro-intestinal. Les microémulsions formées in situ résultant de la consommation des solutions à base d'huile encapsulées comprennent des gouttelettes de microémulsion en phase huileuse de particules liées à un tensioactif monocouche en suspension dans la phase continue aqueuse du tractus gastro-intestinal. Les solutions à base d'huile peuvent également former in situ des liposomes à noyau d'eau en suspension dans la phase continue aqueuse du tractus gastro-intestinal.
Patent CA-3158054-A1 (CA)
Inventor: OSBORN KEVIN
IPC: G06Q20/38
Filed: 2020-11-23
Abstract: Un système et un procédé d'authentification basée sur un PIN à double facteur utilisent un cryptogramme fourni par une carte sans contact associée au client en association avec un PIN stocké par la carte sans contact pour authentifier le client. Dans certains modes de réalisation, l'authentification de cryptogramme peut être préconditionnée lors d'une détermination de correspondance de PIN par la carte sans contact. Dans d'autres modes de réalisation, le cryptogramme peut être formé au moins en partie à l'aide du numéro d'identification personnel (PIN) stocké sur la carte sans contact codée à l'aide d'une clé dynamique stockée par la carte sans contact et associée de manière unique au client. L'authentification peut être réalisée en comparant le cryptogramme formé à l'aide du PIN à un cryptogramme attendu généré par un PIN attendu et une clé dynamique attendue.