baber/WOPTO huggingface dataset:
Patent CR-20210222-A (CR)
Title: Métodos de tratamiento de enfermedad renal crónica con dapagliflozina
Inventor: LANGKILDE ANNA MARIA
IPC: A61P31/12
Filed: 2021-04-01
Abstract: La presente divulgación se refiere a métodos de tratamiento de pacientes con enfermedad renal crónica (ERC), con y sin diabetes tipo 2, con un inhibidor de SGLT2, tal como dapagliflozina.
Patent EC-SP044997-A (EC)
Inventor: JAGTAP PRAKASH G
IPC: A61P29/00
Filed: 2004-02-27
Abstract: The invention provides novel classes of substituted indeno[1,2-c]isoquinoline compounds. Pharmaceutical compositions and methods of making and using the compounds are also described.
Patent EC-SP045140-A (EC)
Title: Formulaciones farmacéuticas derivadas del platino
Inventor: LAURIA SARA
IPC: A61K31/555
Filed: 2004-06-04
Abstract: La presente invención está dirigida a nuevas fórmulas estables de oxaliplatino, en las cuales el ácido láctico y/o una sal farmacéuticamente aceptable funciona como un medio novedoso para preparar una unidad de dosis con una estabilidad mejorada. También está dentro del alcance de esta invención un método para elaborar tales formulaciones listas para ser administradas y su uso en una terapia contra tumores.
Patent EC-SP055914-A (EC)
Inventor: MARK MICHAEL
IPC: A61K31/41
Filed: 2005-07-12
Abstract: The use of the angiotensin II receptor antagonist telmisartan (I) (or its salt) and the 3-hydroxy-2-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor simvastatin (II) is claimed in the production of medicaments (A) for the treatment or prophylaxis of cardiovascular, cardiopulmonary or renal diseases. Independent claims are included for corresponding treatment methods and pharmaceutical compositions. ACTIVITY : Cardiant; Vasotropic; Hepatotropic; Hypotensive; Antilipemic; Antiarteriosclerotic; Antiasthmatic; Antiinflammatory; Antidiabetic; Cerebroprotective; Antianginal; Cytostatic; Antibacterial; Immunosuppressive; Vulnerary; Osteopathic; Neuroprotective; Nootropic. MECHANISM OF ACTION : Angiotensin II receptor antagonist; HMG-CoA reductase inhibitor; Peroxisome proliferator activated receptor-gamma (PPAR-gamma ) regulating gene expression inducer; Matrix metalloproteinase MMP-9 expression controller; Cytokine CD40L antagonist.
Patent EC-SP067121-A (EC)
Title: 3-aminociclopentanocarboxamidas como moduladores de receptores de quimioquinas
Inventor: FENG HAO
IPC: A61K31/4433
Filed: 2006-12-27
Abstract: La presente invención se refiere a compuestos de Fórmula (I): los cuales son moduladores de receptores de quimioquinas. Los compuestos de la invención, y composiciones de los mismos, son útiles en el tratamiento de enfermedades relacionadas con expresión y/o actividad de receptores de quimioquinas.
Patent EC-SP982492-A (EC)
Title: Terapia de interferones polietilenglicol, modificados
Inventor: GLUE PAUL
IPC: A61K38/18
Filed: 1998-04-29
Abstract: Se revela un método que comprende la administarción de un PEG12000-IFN alfa conjugado a un individuo que padece una infección viral, preferentemente hepatitis crónica C, susceptible de un tratamiento con interferón alfa.
Patent FI-20205897-A (FI)
Inventor: KALLIONIEMI JUSSI
IPC: H04L9/32
Filed: 2020-09-17
Abstract: Keksinnön kohteena on menetelmä salatun sähköpostiviestin lähettämiseksi lähettäjältä vastaanottajalle, jossa lähettäjä syöttää (1) palveluun vastaanottajan ja oman sähköpostiosoitteensa, vastaajan ja oman puhelinnumeronsa ja viestin sisällön. Lähettämisen jälkeen lähettäjälle tulee kuittaus lähetyksen tilauksesta sähköpostiin. Kun lähettäjä on vahvistanut (2) sähköpostiosoitteensa kuittauksen vastaanottoviestin kautta, järjestelmä toimittaa viestin sekä salasanan vastaanottajalle. Tämän jälkeen lähettäjä saa kuittauksen siitä, että viesti on toimitettu perille vastaanottajalle. Kun vastaanottaja on salasanan avulla noutanut (5) viestin, järjestelmä lähettää tästä kuittauksen (6) viestin lähettäjälle.
Patent GB-1049371-A (GB)
IPC: B28B11/24
Abstract: 1,049,371. Drying ceramic ware. SERVICE (ENGINEERS) Ltd. Nov. 28, 1962 [Aug. 29, 1961], No. 31011/61. Heading F4G. Articles of ceramic ware are dried by passage in moulds 34 carried by the pendant horizontal shelves 20 of a first conveyer 18 through a drying unit 10 heated by air from a heating unit 14 to an exit 30 where the ware is transferred from the moulds and is inverted during transfer to a second coneyer 46 in a second drying unit 12 which is heated by infra-red heaters (not shown). The transfer means comprises suction devices 38, each carried by an arm 40 mounted on a horizontal rotatable shaft 42 and comprising a ribbed plastic pad having a surrounding flexible apron connected to a source of vacuum. The devices 38 are adapted to operate in timed relation with the step-by-step movement of the conveyer 18 so as to overlie the articles thereon, raise and swing the ware to a position in which the devices deposit the ware on to annular supports 44 on the conveyer 46, which supports are partially cutaway to allow each arm 40 to pass therethrough. A cooling chamber 50 may be provided.
Patent GB-1050611-A (GB)
IPC: D06B1/00
Abstract: 1,050,611. Treating textile material. L. DEVYLERRE. Feb. 10, 1964 [Sept. 14, 1963] No. 5404/64. Heading D1L. A machine for continuously treating textile material with fluid and particularly with steam comprises a perforated duct 1, into which e.g. steam may pass from a steam jacket and through which the material is conveyed by an endless chain 2, the material e.g. carded silver, being fed into the duct by rollers, 4a, 4b each of which has a groove therein, for the reception of a block 7 having a bore 9 for the passage of the chain and a tapered portion 8 directed into the duct. The chain 2 which comprises horizontal links 10 connected by vertically arranged flat plates 11 having pins 11a mounted therein, is driveable by a motor 22 at a speed several times less than the peripheral speed of the rollers 4a, 4b thus compressing the material in the duct. The motor 22 and the motor 20 which drives the rollers 4a, 4b are connected to a controller 26 to ensure the maintenance of the desired speed ratio. An end portion 3d of the duct has doors 12, 13 therein which are operable by toothed segments 15 and a rack 16, the rack being attached to a piston 18 inside a cylinder 19. The inside of cylinder 19 is connected via a bore in the piston rod with the interior of jacket 3 so that the tendency of the steam pressure to force the material through the doors is counteracted by the tendency of the steam pressure to hold the doors 12, 13 closed. The rollers 4a, 4b may be moveable apart against spring action.
Patent GB-1050654-A (GB)
IPC: B21D22/20
Abstract: 1,050,654. Stamping. ALLMANNA SVENSKA ELEKTRISKA A.B. March 25, 1964 [March 30, 1963], No. 12565/64. Heading B3Q. An hydraulic stamping press comprises pistons 3, 4 in cylinders 1, 2, means 27, 33 for clamping work 23 and being movable to form the work over a stationary die 24, and a substantially closed pressure circuit connecting the cylinders and including a circulation pump 10, Fig. 1 (not shown), so that pressure - fluid expelled from cylinder 2 during a stamping operation may be supplied to cylinder 1. Coupled throttle valves 14, 15, receiving control impulses from an automatic regulator 19, may increase or decrease the clamping pressure on the work. The valve 15 exhausts into a reservoir 13 from which fluid may be drawn by a further pump 12 for increasing the circuit pressure. The regulator 19 may be fed with impulses at 20 relating to the displacement of the clamping device, and with others giving the pressure in the circuit. These are compared in the regulator with a pre-set value depending on the displacement, and any deviation between desired and actual values converted into control impulses which actuate valves 14, 15 to increase the holding force as the operation proceeds. As depicted, Fig. 2, an extension 26 of piston 3 works in a cylinder 25 closed at the lower end by a rubber membrane 33 which forces the work 23 against the die 24 and a clamping member 27 carried by the lower piston 4. The pistons 3, 4 are raised by auxiliary pistons 29, 30. During the stamping operation, the lower piston 4 moves faster than the piston 3.
Patent GB-1053502-A (GB)
IPC: B23H1/02
Abstract: 1,053,502. Spark erosion. DEUTSCHE EDELSTAHLWERKE A.G., and ALLGEMEINE ELEKTRICIT€TS - GESELLSCHAFT. Jan. 20, 1965 [Jan. 20, 1964], No. 2523/65. Addition to 981,464. Heading B3V. In a modification of the invention of Specification 981,464, the spark gap 6 is supplied from a trigger pulse generator 1 without any intermediate energy storage means. A D.C. reference source 8 charges through resistance 11, a monitoring capacitor 16. When the voltage across this capacitor builds up as the result of deionization of the gap, a device 12 is energized to trigger the pulse generator into applying the next spark pulse through inductor 5 to the spark gap 6. Device 12 may comprise a Schmitt trigger circuit.
Patent GB-1053643-A (GB)
IPC: H02M3/337
Abstract: 1,053,643. Converting. UNITED AIRCRAFT CORPORATION. June 28, 1963 [Sept. 4, 1962], No. 25804/63. Heading H2F. [Also in Division G3] A voltage regulator comprises an autotransformer connected to pass part of the power supplied to a load, means for producing a signal when the voltage across the load falls below a reference value, and switch means which are operated in dependence upon said signal to induce current flow in the transformer in a sense to increase the voltage across the load. As shown, a load 12 is supplied from a D.C. source by way of the halves A and B of an auto-transformer T 1 , diodes D 1 , D 2  and a filter circuit L 1 , C 1 . Switching transistors Q 1 , Q 2 , connected to further tappings on the autotransformer T 1 , can be rendered conducting by pulses applied over transformers T 1  and T 3 . These pulses have a variable width depending on the difference between the actual and desired output voltages, and are derived from a circuit including a comparator 14, a pushpull driver circuit connected to transistors Q 1 , Q 2 , and a sawtooth voltage generator which is itself driven from an oscillator over a diode switch (Fig. 1, not shown). The transistors Q 1  and Q 2  are thus alternately turned on and off at a constant frequency determined by the oscillator, the period that each switch is on being controlled by the width of the pulses. The arrangement is such that the alternate closing of the switching transistors results in increasing total current flow through alternate halves of the transformer winding and the current flow in one half of the winding causes a voltage to be induced in the opposite half of the winding. This induced voltage applied over diode D 1  or D 2  to capacitor C 1  is combined with the source voltage so that the output voltage tends to remain constant. The clamping diode D 3  prevents damage to transistors Q 1  and Q 2  when the supply voltage is turned off.
Patent GB-1084283-A (GB)
IPC: H01R13/422
Abstract: 1,084,283. Two-part couplings. PLESSEY-UK Ltd. June 26, 1964 [May 17, 1963], No. 19706/63. Heading H2E. In an electrical in-line connector, a socket contact 1 and a pin contact 7, each having a generally cylindrical outer surface are each located in a sleeve (19 and 12 respectively) of resiliently insulating material such as nylon or polypropylene by flanges 3a, 8, 8a on the contacts and corresponding grooves 21, 14, 15 in the sleeves. The sleeve 19 has an extension 23 fitting over the sleeve 12, the extension 23 and sleeve 12 being provided with a circumferential ridge 24 and a groove 18 respectively, or vice versa, which snap into mutual engagement to retain the connector halves in a fully engaged position. The connector is assembled by forcing each contact into its associated sleeve, the flanged portions of each contact being provided with lead-in tapers to facilitate this assembly. Wires 5, 11, are connected to end bush portions 3 and 10 of the contacts, for example by crimping or soldering.
Patent GB-1226360-A (GB)
IPC: C09D5/10
Filed: 1968-08-16
Abstract: 1,226,360. Alkali metal silicate paints. HENKEL & CIE G.m.b.H. 16 Aug., 1968 [18 Aug., 1967], No. 39305/68. Heading C4A. A metal-dust/alkali metal silicate paint comprises an organic nitro compound soluble therein and boric acid or a borate. The preferred metal dust is zinc. Sodium or potassium silicates with a molar ratio SiO 2 : alkali metal oxide of 3À8-4À4:1 are preferred, particularly those containing 0À1-2% by wt. of a quaternary ammonium hydroxide RR<SP>1</SP> 3 N<SP>+</SP>OH<SP>-</SP>, where R is C 1 -C 4  alkyl, and R<SP>1</SP> is C 1 -C 12  alkyl or alkanol, e.g. (C 2 H 5 ) 4 N<SP>+</SP>OH<SP>-</SP>. Specified nitro compounds are nitromethane, nitroacetic acid, nitrobenzoic acid, nitrophenol, dinitrophenol, nitroresorcinol, nitropyrocatechol, nitrourea and nitroguanidine, used in an amount 0-1-5% by weight of the solid alkali metal silicate. Boric acid and potassium, sodium or ammonium borates are specified in an amount 0-5-3% by wt. of the silicate. Optional ingredients are alginate, starch or methyl cellulose thickeners, polyethoxy emulsifiers, and kaolin, bentonite, montmorillonite or zinc oxide fillers.
Patent GB-1230727-A (GB)
IPC: B23Q16/10
Filed: 1969-05-30
Abstract: 1,230,727. Indexing; lathe turrets. HARDINGE BROS. Inc. 30 May, 1969, No. 27447/69. Headings B3B and B3T. An indexing mechanism, e.g. for a lathe turret, comprises a base 12 and a top plate 15 having mutually engageable plane surfaces 20, 22 for frictionally locking the base and top plate together when in indexed relation, and a pair of teeth 26 (Figs. 1 and 3) resiliently mounted on diaphragms 28 on the base 12, the teeth being adapted to engage complementary grooves 24 in the top plate to index the latter precisely before the surfaces 20, 22 reach the position of frictional engagement. The top plate 15 is mounted on a hub 32 which is splined to and axially movable with a central shaft 60, axial movement of which is effected by fluid pressure piston 66 while angular movement is effected through gearing 88, 90 from an indexing source not shown. The spline connection 61 is made loose-fitting to allow for any slight transverse positioning movement of the plate 15 caused by the teeth 26 and a preloaded bearing 44 is supported within a support ring having outer and inner ring parts 46, 48 connected by thin radially extending webs 50 which permit the centre shaft 60 to float slightly for the same purpose. The plate 15 is accurately located on the hub 32 by means of conical surfaces 40 and screws 42 in order to facilitate the presetting of tools using a fixture of similar construction and employing a microscope for setting the tool points. As shown, the base 12 is mounted on a lathe carriage 11 slidable on a dovetail slideway 10.
Patent GB-1231273-A (GB)
IPC: C07C1/00
Filed: 1968-04-02
Abstract: 1,231,273. Disproportionating olefins. PHILLIPS PETROLEUM CO. 2 April, 1968 [3 April, 1967], No. 52229/70. Divided out of 1,231,272. Heading C5E. In the catalytic disproportionation of olefins, the feed of one or more olefins is contacted with MgO at a temperature below which any substantial isomerization takes place, prior to contact with the disproportionation catalyst. The MgO is preferably activated prior to contact with the olefin by heating in an oxygencontaining gas stream at 500-1500‹ F. The disproportionation catalyst may be: (1) activated SiO 2  or thoria promoted with an oxide (or precursor thereof) of Mo, W or Re; or by a sulphide of W or Mo; (2) activated Al 2 O 3  promoted by an oxide (or precursor thereof) of Mo, W or Re; or by a sulphide of W or Mo; or by an alkali metal salt, alkaline earth metal salt, NH 4 <SP>+</SP> salt or Bi salt of phosphomolybdic acid; (3) activated phosphates of Al, Zr, Ca, Mg or Ti promoted by an oxide (or precursor thereof) of Mo, W or Re or by a sulphide of W or Mo or by magnesium tungstate or by beryllium phosphotungstate; or (4) activated SiO 2 , Al 2 O 3 , phosphates of Al, Zr, Ca, Mg or Ti promoted by hexacarbonyl of W or Mo. Examples describe the disproportion of pentene-1 and of a mixture of heptene-2 and heptene-3.
Patent GB-1232495-A (GB)
IPC: B21J15/02
Filed: 1968-12-10
Abstract: 1,232,495. Blind riveting tools. SWINGLINE Inc. 10 Dec., 1968 [8 May, 1968], No. 58622/68. Heading B3U. A blind riveting tool comprises a mandrel pulling device driven by a fluid actuated piston member comprising two interconnected piston heads 26, 27 which are positioned in separate cylinder compartments 21, 22 and which are biased into a non-actuating position by springs 28, 38. A stem 30 is connected at one end to a support 24 interconnecting the pistons 26, 27 and at the other end to a puller member 33 operatively connected to three mandrel gripping jaws. After the mandrel 41 of the rivet has been inserted between the jaws of the tool, a trigger 51 is pushed upwardly to cause air under pressure to flow from a chamber 14, through a conduit 47, trigger housing 16, conduit 65 and conduit 19 thereby raising the pistons 26, 27. The rivet is set by the upward movement of the jaws, the broken off mandrel being expelled through an opening 40 in the housing 32. When the trigger 51 is released, it is forced downwards by the air pressure within the housing 16 causing the air within the chambers 21, 22 to be exhausted to atmosphere through conduits 19, 65, trigger housing 16 and conduit 17. The pistons 26, 27 are returned to their initial positions by the springs 28, 38.
Patent GB-1233065-A (GB)
IPC: C09B62/485
Filed: 1968-08-12
Abstract: 1,233,065. Azophthalocyanines. FARBWERKE HOECHST A.G. 12 Aug., 1968 [12 Aug., 1967], No. 38472/68. Heading C4P. The invention comprises azophthalocyanine dyestuffs of the general formula wherein P c  is an optionally metallized (e.g. Cu, Co, Ni) phthalocyanine radical, A is -D-N=N-K- or -K-N=N-D- where in D is a diazo component radical and K a coupling component radical both optionally containing water-solubilizing groups, R 1  and R 2  are H, alkyl, aralkyl or aryl which may be substituted or both together with the N atom form an alkylene-imine ring, R 3  and R 4  are H or C 1 -C 4  alkyl, a, b and c are each 1-4, their sum being at most 6 and Z is a group of the formula or a group of the formula wherein R 5 , R 6  and R 7  are H, Cl, OH, alkyl, alkenyl, alkoxy, phenyl, phenoxy, cyano, nitro, sulphonic acid, carboxylic acid alkyl ester, N- mono- or di-alkyl sulphonic or carboxylic acid amide, alkyl- or phenyl-sulphonyl, or R 5  and R 7  together represent a bond between C<SP>1</SP> and C<SP>4</SP>, X 1  and X 2  are each halogen and n is 0 or 1. D is preferably a radical of the benzene, naphthalene, diphenyl or diphenyl ether or stilbene series and K is a radical of the benzene, naphthalene, acetoacetic acid arylamide or pyrazolone series which contains at least one OH or amino group. They are prepared by (a) diazotizing a phthalocyanine having a group -SO 2 -N(R 3 )-D-NH 2  and coupling with a compound H-K-N(R 4 )-Z, (b) reacting an azophthalocyanine having a group -SO 2 -N(R 3 )-A-N(R 4 )H with an acid chloride Z-Cl or (c) reacting a phthalocyanine sulphonic acid chloride P c (SO 2 Cl) m , where m is 1-4 with an amino azo compound of the formula HN(R 3 )A-N(R 4 )Z and optionally with an amine HN(R 1 )R 2  and then saponifying any residual -SO 2 Cl groups. They are used to dye wool, silk, leather, polyamides, linen, regenerated cellulose and cotton in olive, green, violet and grey shades.
Patent GB-1234598-A (GB)
IPC: A61Q5/10
Filed: 1968-12-16
Abstract: 1,234,598. Dyestuff compositions. L'OREAL. 16 Dec., 1968 [15 Dec., 1967; 23 Aug., 1968], No. 59731/68. Heading D1B. [Also in Division C2] Compositions for dyeing keratinic fibres, e.g. hair, comprise (1) at least one aromatic or heterocyclic oxidation dye containing two amino groups, or an amino group and a hydroxy group, ortho - or para - to each other and (2) at least one coupling agent of formula: wherein R 1  is (a) a radical of formula: wherein A is a hydroxy group, in which case Y is a C 1-6  alkoxy group, or A is a hydrogen atom or an alkoxy group, in which case Y is a hydroxy group or a group -NR 5 R 6  in which each of R 5  and R 6  is a hydrogen atom or a C 1-6  alkyl or aryl group, both of R 5  and R 6  not being aryl groups, and each of M, M' and M" is a hydrogen or halogen atom or a hydroxy, amino, C 1-6  alkyl, C 1-6  alkoxy or aryl group, or (b) a radical of formula: n which each Z is a nitrogen atom or a radical =CH- 2  provided that at least one Z is a nitrogen atom, or (c) a monovalent optionally substituted hydroxynaphthyl or aminonaphthyl group, or (d) a radical of formula: in which A 1  is an aryl group and R 7  is a C 1-6  alkyl or aryl group, or (e) a radical of formula: in which A 2  is a C 1-6  alkyl or aryl group, or (f) a radical of formula: in which R 4  is a methyl or phenyl radical, X is oxygen or sulphur, each of R 2  and R 3  are hydrogen atoms or C 1-6  alkyl, -CH 2 CONH 2  or -CH 2 CON(C 2 H 5 ) 2  groups, and R 2  is a radical as defined for R 1  above or is a hydrogen atom or a C 1-6  alkyl, aryl or other substituted aryl group. The compositions may additionally contain other dyestuffs, e.g. direct dyes, such as azo-, anthraquinone and metalcontaining dyes, or dyes obtained by combining oxidation dyes with other coupling agents, or wetting agents, dispersing agents and penetrating agents. A pHo range of 7 to 11 is preferred, obtainable by addition of ammonia. The compositions may be used in the form of aqueous solutions, creams or gels, and may be applied in conventional manner with an oxidising agent, e.g. hydrogen peroxide, followed by rinsing, shampooing and drying.
Patent GB-1239173-A (GB)
IPC: F02M35/04
Filed: 1969-08-29
Abstract: 1,239,173. I.C. engine intake air filter. FILTERWERK MANN & HUMMEL G.m.b.H. 29 Aug., 1969 [10 Sept., 1968], No. 43063/69. Heading B1T. [Also in Division F1] The intake air filter 5 of an I.C. engine has an induction pipe comprising straight section 7 and elbow section 8, section 8 being pivotable about the axis of section 7 to enable warm air heated by the exhaust pipe to be drawn into the engine in winter, sections 7 and 8 both being made of plastics and a metal extension pipe 9 being moulded into the free end of section 8 (Fig. 3, not shown).
Patent GB-1251471-A (GB)
IPC: F25D17/00
Filed: 1970-04-17
Abstract: 1,251,471. Containers. SOC. FERROVIAIRE INTERNATIONALE DE TRANSPORTS FRIGORIFIQUES INTERFRIGO. 17 April, 1970 [21 April, 1969], No. 18410/70. Heading F4H. A container, which can be mounted on a railway vehicle or a road vehicle, comprises an upper wall 3 which defines with the outer wall a gap which is divided into two passages 5A, 5B by a diagonal partition 7 and a lower wall 21 which is spaced from the lower wall of the container to define therewith a horizontal gap which is divided into two passages 25A, 25B by a diagonal partition 23, extending generally transversely to the partition 7. The walls 3 and 21 abut against opposed side walls 1A and 1B of the container 1, the inner surface of the side walls 1A, 1B having a plurality of vertically extending ribs defining sets of channels 27 and 29 respectively. Air cooled by the conditioner 19 traverses a circuit around the load (shown as arrows f 1 -f 24 ). Valve means may be disposed at the juncture of the end and upper outer wall of the container (f 8 ). If the load is impervious to air, a partition 41 may be disposed on the underside of the upper wall 3, to prevent the air flowing along the paths f 3  and f 9  from intermingling.