baber/WOPTO huggingface dataset:
Patent EP-0327284-B1 (EP)
Inventor: WADE JAMES J
IPC: C07D498/14
Filed: 1989-01-30
Granted: 1994-08-17
Abstract: Substituted 1,2,4-triazolo[1,5-c]pyrimido[1,4]-azines of formula <CHEM> wherein A is methylene or carbonyl; B is methylene, carbonyl or -CHR9-; Q is N-R7 or O; Y is N-R10, O, S, SO or SO2; R2 is hydrogen or alkyl; R5 is alkyl; R7 is hydrogen, alkyl, benzyl or acetyl; R9 is alkyl; R10 is alkyl or benzyl; have been found to have potent bronchodilator activity. Pharmacological methods for inducing bronchodilation using such compounds, pharmaceutical compositions containing such compounds, and synthetic intermediates for preparing such compounds are also described.
Patent EP-0332463-B1 (EP)
Inventor: PENNINGTON DONALD C JR
IPC: C22C29/08
Filed: 1989-03-10
Granted: 1994-07-27
Abstract: A hard, relatively non-brittle, cemented carbide body is made by sintering pressed grade carbide powders in the presence of a boron-containing material such as boron nitride. During sintering, appreciable quantities of boron migrate or diffuse into the body to become incorporated throughout the microstructure of the carbide resulting in the formation of a third quarternary phase comprised of tungsten, cobalt, boron and carbon.
Patent EP-0363151-B1 (EP)
Inventor: NOBLE PHILIP C
IPC: A61F2/00
Filed: 1989-10-03
Granted: 1995-12-20
Abstract: The bone prosthesis of the present invention comprises a first body member (2) or stem for placement into a bone cavity, such as an intramedullary canal. The body member (2) is configured and dimensioned so as to provide a nonuniform interference press-fit. The apparatus further comprises a second body member or broach (80) for placement into and removal from a bone cavity, the broach (80) configured and dimensioned so as to prepare the bone cavity so as to provide a nonuniform interference press-fit with the stem (2). The apparatus further comprises a distal sleeve (32) configured and dimensioned so as to be attached to the stem so as to centralize the stem in the bone cavity. The distal sleeve (32) preferably is provided with an interior conical slope and an exterior conical slope on a portion thereof to aid in insertion into the canal. The stem (2) further comprises at least one groove (27) and preferably a plurality of grooves (27) along its corners. These grooves (27) are nonparallel to the longitudinal axis of the stem (2) and do not extend over any one entire side of the stem (2). The stem (2) can be provided with an area of cancellous texture which comprises substantially randomly patterned array of multiple curved-line surface unevenness, such as indentations or protrusions. The present invention also is directed to a method comprising utilization of the broach (80), the stem (2) and the distal sleeve (32) so as to provide a nonuniform press-fit between the bone prosthesis and the bone cavity while centralizing the stem in the bone cavity.
Patent EP-0372962-B1 (EP)
Inventor: FORBES IAN THOMSON BEECHAM PHA
IPC: C07D209/42
Filed: 1989-12-07
Granted: 1994-07-20
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: <CHEM>  wherein: R1 is hydrogen, C1-6 alkyl, C3-6 cycloalkyl, C3-6 cycloalkyl-C1-4 alkyl, C2-6 alkenyl or C2-6 alkynyl; R2, R3 and R4 are independently selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxycarbonyl, C1-6 alkylthio, hydroxy, C2-7 alkanoyl, chloro, fluoro, trifluoromethyl, nitro, amino optionally substituted by one or two C1-6 alkyl groups or by C2-7 alkanoyl, cyano, carbamoyl and carboxy, and phenyl, phenyl C1-4 alkyl or phenyl C1-4 alkoxy in which any phenyl moiety is optionally substituted by any of these groups; R5 and R6 are independently selected from hydrogen, C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-4 alkyl, C2-6 alkenyl, C1-7 alkanoyl, C1-6 alkylsulphonyl, di-(C1-6 alkyl)amino C1-6 alkyl, 3-oxobutyl, 3-hydroxybutyl, and phenyl, phenyl C1-4 alkyl, benzoyl, phenyl C2-7 alkanoyl or benzenesulphonyl any of which phenyl moieties are optionally substituted by one or two halogen, C1-6 alkyl, C1-6 alkoxy, CF3, amino or carboxy, or R5 and R6 together are C2-6 polymethylene optionally interrupted by oxygen or NR11 wherein R11 is hydrogen or C1-6 alkyl optionally substituted by hydroxy; R7, R8, R9 and R10 are independently selected from hydrogen, C1-8 alkyl optionally substituted by one or two hydroxy, oxo, C1-4 alkoxy, halogen or CF3 groups, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-4 alkyl, C2-7 alkanoyl, C2-6 alkenyl or C2-6 alkynyl either being optionally substituted by one, two or three halogen atoms or C1-4 alkyl, C3-7 cycloalkenyl optionally substituted by one or two halogen or C1-4 alkyl groups, C3-7 cycloalkenyl-C1-4 alkyl in which the cycloalkenyl ring is optionally substituted by one or two halogen or C1-4 alkyl groups, and phenyl optionally substituted by one or two halogen, C1-6 alkyl, C1-6 alkoxy, CF3, amino or carboxy, or R7 and R8 together and/or R9 and R10 together are C3-6 polymethylene optionally substituted by C1-6 alkyl or C2-6 alkenyl; and Z is (CR14R15)n where n is 0, 1 or 2 and R14 and R15 are independently selected from hydrogen, C1-6 alkyl or C2-6 alkenyl.
Patent EP-0375452-B1 (EP)
Inventor: GIRODEAU JEAN-MARC MARIE MAURI
IPC: A61K31/22
Filed: 1989-12-21
Granted: 1994-10-05
Abstract: The invention concerns a cycloalkane derivative of the formula I,   <CHEM>  wherein Ar<1> is optionally substituted phenyl or naphthyl; A<1> is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo-(3-6C)alkylene; Ar<2> is optionally substituted phenylene, or a 6 membered heterocyclene moiety containing up to three nitrogen atoms; R<1> is hydrogen, (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; and R<2> and R<3> together form a (3-6C)alkylene group which defines an optionally substituted ring having 4 to 7 ring atoms;  or a pharmaceutically-acceptable salt thereof. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.
Patent EP-0332552-B1 (EP)
IPC: A01D34/66
Filed: 1989-03-01
Granted: 1992-10-07
Abstract: The present invention relates to an agricultural machine for the harvesting of fodder, comprising a chassis equipped with a drawbar and with carrier wheels, said chassis carrying a cutting device, a conditioning and/or throw-off device and orientable deflectors. 
<??>It is notable in that the cutting device (50) and the conditioning and/or throw-off device (54) can be transferred into a second working position, in which they form an acute angle ( alpha ) with a straight line (D) perpendicular to the direction of advance (A) and acute angles ( beta ) with the axes (38 and 39) of the carrier wheels (36 and 37), said angles ( beta ) having substantially the same value as the abovementioned angle ( alpha ). 
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Patent EP-0360755-B1 (EP)
Inventor: SCHURR MICHAEL
IPC: H01B7/29
Filed: 1989-09-15
Granted: 1994-05-18
Abstract: Electrical conductors having an internal insulating layer of heat resistant polymer or of inorganic material and an outer protective layer, indissolubly connected to the inner layer, of flame-retardant thermoplastic or duroplastic can be wound at low bending radii without the formation of folds in the protective layer. Moreover, they have an improved resistance to liquid media. The outer protective layer is preferably applied using a powder coating process.
Patent EP-0418388-B1 (EP)
Inventor: TORII NOBUTOSHI ROOM
IPC: B25J9/04
Filed: 1989-08-11
Granted: 1994-12-28
Abstract: A light, miniaturized horizontal articulated robot capable of being moved in a large space, and fabricated, assembled, maintained and transported at reduced costs. A ball screw (21) in a direct-acting actuator (100) is supported rotatably at its upper end on an upper plate of a column (10), and connected at its lower end to a driving unit (40) provided on a base plate of the column. A first link (220) is connected pivotably to a connecting member (210) of a manipulator (200) fixed to a slider (30) in the actuator, and a second link (240) to the first link. The ball screw is turned by the driving unit to move the manipulator with the slider along the ball screw, and a servomotor (230, 250) for the manipulator is driven to turn the two links in a horizontal plane, whereby robot work is carried out as wrist of the robot is positioned in a robot-provided space. Since a base on which the actuator is supported pivotably is not required, the robot can be made smaller in dimension and weight at a lower cost, and the space of movement of the robot becomes large owing to the low downward movement limit position of the manipulator.
Patent EP-0408675-B1 (EP)
Inventor: SCANLON KEVIN J
IPC: C07H21/04
Filed: 1989-08-16
Granted: 1997-12-17
Abstract: Changes in tumor cell RNA and DNA are utilized to detect the progression and the temporal changes in resistance to chemotherapy in human tumors.
Patent EP-0410237-B1 (EP)
Title: Knee joint endoprosthesis
Inventor: SCHELHAS KLAUS-DIETER
IPC: A61F2/38
Filed: 1990-07-14
Granted: 1993-11-10
Abstract: The knee joint prosthesis has convex condylar shells (4) at the bottom end of the stem (14) of the femoral half (2), and a plate (24) at the top end of the stem (22) of the tibial half (20), together with an insert on the plate with mating concave surfaces for the condylar shells. A connecting component, hinged on a transverse pin (60) in the femoral half protrudes into the space between the shells. The lug (56) on the connecting component slides freely in the axial direction. The shells are curved about an axis parallel to and above the hinge axis (62). The distance between the two axes can be less than the transverse pin dia.
Patent EP-0412337-B1 (EP)
Title: Method for the production of 1,3-propandiol
IPC: C07C31/20
Filed: 1990-07-20
Granted: 1993-09-01
Abstract: A method for preparing 1,3-propanediol is disclosed which comprises the hydration of acrolein in the presence of an acidic cation exchanger resin and the hydrogenation of the 3-hydroxypropionaldehyde obtained in the first stage. The volume-time yield was able to be increased in the hydration stage by using a cation exchanger resin with phosphonic acid groups, preferably a cation exchanger with chelating aminophosphonic acid groups. The hydrogenation catalyst can be repeatedly reused without appreciable loss of activity.
Patent EP-0411539-B1 (EP)
Title: Lubricating oil compositions and their use for lubricating gasoline-fueled and/or alcohol-fueled, spark-ignited engines.
Inventor: CHAMBERLIN III WILLIAM B
IPC: C10N10/02
Filed: 1990-07-30
Granted: 1994-12-21
Abstract: A lubricating oil composition is described which is useful in spark-ignited engines which may be fueled with gasoline, alcohol, or mixtures of both. More particularly, lubricating oil compositions for spark-ignited engines are described which comprise (A) an oil of lubricating viscosity; (B) at least one detergent selected from the group consisting of a basic magnesium salt of an organic acid or a mixture of at least one basic magnesium salt of an organic acid and another alkaline earth metal salt of an organic acid wherein the metal in the mixture is predominantly magnesium; and (C) at least one metal salt of (C-1) a substituted succinic acid acylated polyamine; or (C-2) a hydrocarbon-substituted aromatic carboxylic acid containing at least one hydroxyl group attached to an aromatic ring, provided that the metal of said metal salt (C) is not calcium or magnesium. Lubricants primarily useful for lubricating alcohol-fueled, spark-ignited engines also are described which comprise (A) a lubricating oil, (B) a detergent as described above, and (D) at least one carboxylic acid derivative composition useful as a dispersant. The oil compositions of the invention also may contain, and generally do contain other desirable additives such as (E) mixtures of metal salts of dihydrocarbyl phosphorodithioic acids; (F) sulfurized olefins; etc. In one embodiment, the oil compositions of the present invention contain the above additives and other additives described in the specification in amounts sufficient to enable the oil to meet all the performance requirements of the API Service Classification identified as "SG".
Patent EP-0412575-B1 (EP)
Inventor: URBANSKY RALPH DIPL-ING
IPC: H04J3/07
Filed: 1990-08-09
Granted: 1996-01-03
Abstract: A stuffing decision circuit is described which is used in an arrangement for the bit rate adaptation of two signals. It is necessary for the application of the stuffing decision circuit according to the invention that the signal with the higher bit rate is structured in accordance with frames and at least one stuffing decision must be made for each frame. To make the so-called waiting time jitter, which becomes noticeable during the recovery of the signal with the lower bit rate at the receiving end, largely removable, means are provided by means of which the time of the stuffing decision is randomly or pseudorandomly shifted by times which are short compared with one frame length. Due to this modulation of the decision time, the low-frequency jitter otherwise occurring is transformed into higher frequencies and can be easily filtered out by means of a phase-locked loop at the receiving end.
Patent EP-0415458-B1 (EP)
Inventor: KLIGMAN ALBERT M
IPC: A61K31/23
Filed: 1990-09-01
Granted: 1994-03-16
Abstract: Striae distensae lesions may be prevented and/or reduced in size by topically applying to the skin affected with the lesions an effective amount of a retinoid, preferably retinoic acid, preferably by daily application in a dermatologically acceptable vehicle, such as a cream base, at a concentration of about 0.025 to 0.1 weight percent retinoic acid. When applied during the striae rubrae stage, the retinoid may be effective to prevent the formation of striae albae lesions, and when applied in either stage, the retinoid may be effective to reduce the width and depth of the lesions, with improved texture and softness.
Patent EP-0476166-B1 (EP)
Inventor: HAME ERICH
IPC: A47G7/04
Filed: 1990-09-18
Granted: 1994-06-01
Abstract: The application relates to a flower tub support, such as is primarily used on terraces and balconies of residential properties, but also on open-air lawns, which is suitable for flower tubs of widely varying sizes and shapes. <IMAGE>
Patent EP-0426101-B1 (EP)
Inventor: KAISER HARTMUT
IPC: B29C48/03
Filed: 1990-10-30
Granted: 1994-09-14
Abstract: Barrel component for a twin-screw extruder for processing thermoplastic material and mixtures of plastics, comprising a barrel material and a wear-inhibiting material. The barrel component has two receiving chambers for the extruder screw shanks, which penetrate octagonally. The wear-inhibiting material is arranged on the receiving chamber side as a hard-phase layer. The barrel component is a one-piece component. It has, both in the barrel material region and in the hard-phase layer region, an isotropic structure of powder-metallurgical origin with HIP texture. The barrel material region and the hard-phase layer region are joined by a diffusion layer. - A method of manufacture is also specified.
Patent EP-0439784-B1 (EP)
Inventor: HAZENBROEK JACOBUS E
IPC: A22C17/04
Filed: 1990-12-19
Granted: 1994-09-21
Abstract: The deboner (10) carries a plurality of modules (11) in a closed path through a series of processing stations. Each module includes a rotary bone holder (30) that supports one end of a poultry bone (85) and a stripper assembly (31) that is moved toward and away from the bone holder. The stripper blades (55, 56) engage the poultry part and stretch the meat, skin, etc., holding it taut while the thigh is moved through a cutting station. The stripper assembly is then moved away from the bone holder and then upwardly again to engage the bone and to strip the meat from the bone. As the blades strip the meat from the bone, the rotary bone holder is rotated by its sprocket engaging the sprocket (36) turning protrusions (45). <IMAGE>
Patent EP-0392634-B1 (EP)
Inventor: BECHEM HERBERT
IPC: F24H9/12
Filed: 1990-04-11
Granted: 1994-06-22
Abstract: A heatable domestic water tank has a cold-water supply pipe (9), which passes through the tank space (1) and opens into its lower region, and a hot-water draw-off pipe (10) which starts from its upper region. In order to prevent the temperature of the hot water which is drawn off, for example in the case of repeated tappings, exceeding a limit value and reaching an inadmissibly high level, there is provided a branch pipe (11) which branches off from the cold-water supply pipe (9) and opens into the upper region of the tank space (1) and in which there is arranged a valve (12) which is thermostatically controlled depending upon the temperature of the water stored in the upper tank region and opens in the event of a temperature limit value being exceeded. <IMAGE>
Patent EP-0382562-B1 (EP)
Inventor: HOLLIS CECIL GEORGE
IPC: C08G73/06
Filed: 1990-02-09
Granted: 1995-09-20
Abstract: Polymeric quaternary ammonium trihalides, preferably triiodides, and use of polymeric quaternary ammonium trihalides to inhibit the growth of microorganisms in aquatic systems, to disinfect or sanitize surfaces and to disinfect the skin of animals, including humans.
Patent EP-0389303-B1 (EP)
Inventor: JENKINS PETER DAVID
IPC: G02B6/46
Filed: 1990-03-23
Granted: 1996-09-25
Abstract: An optical fibre storage system comprising a container in which turns of fibre (4) are wound in a substantially helical formation, the diameter of the turns and container being such the turns of fibre are maintained in position by their natural resilience pressing them outwardly against the inside of the container (5). The inside of the container may be coated to aid location of the turns. In another embodiment an inflatable member located within the turns is inflated to press against them to aid positional stability. A source of gas may be connected to the container to enable propulsion of the fibre out of the container in a duct, or the container itself may be pressurised.
Patent EP-0407076-B1 (EP)
Title: Optical fibre cable
IPC: G02B6/44
Filed: 1990-06-25
Granted: 1993-07-21
Abstract: An optical fibre cable has a channel (2) loosely housing an optical ribbon element (3) and a non-optical ribbon element (3A) which both have an evenly distributed excess length of between 0.5% and 1% and adopt a regular undulating configuration in a thixotropic water blocking gel (28) in the channel.
Patent EP-0384817-B1 (EP)
Title: Plant for making prestressed concrete articles, in particular elongate construction elements
IPC: B28B7/36
Filed: 1990-02-16
Granted: 1992-10-28
Abstract: Plant for making prestressed concrete articles, comprising an elongate production area (10), means (20, 22) for tensioning prestressing armatures (24) and a moulding apparatus comprising a mobile unit (18) supporting a multiplicity of mould elements (34, 36, 38) parallel to the longitudinal direction of the production area. Each mould element comprises, at its rear end, an end-shaping device (42, 44, 46) making it possible to shape to precise dimensions the transverse cross-section of the moulded elements (P1, P2). <IMAGE>
Patent EP-0388269-B1 (EP)
Inventor: MALBEC EDOUARD
IPC: F04C5/00
Filed: 1990-03-12
Granted: 1994-01-26
Abstract: The cartridge (7) is comprised of a housing (8) which comprises, in the vicinity of each of its ends, a cylindrical raceway (16, 17) against which are capable of applying and rolling bevel gears (9) which crush the flexible tube (2) located between both raceways. The bevel gears (9) are tubular and freely mounted inside the housing (8), within the concavity of the flexible tube, this housing comprising, at least on one side, a central opening (13) with a diameter large enough to enable the driving of the bevel gears either directly from a rotary disc (5) provided with planet gears (22) capable of engaging into the tubular bevel gears or from a shaft internally engaged between the tubular bevel gears.
Patent EP-0413622-B1 (EP)
Inventor: BECQUART JEROME
IPC: C12P21/04
Filed: 1990-08-02
Granted: 1998-02-11
Abstract: Utilization of albumin as a stable plasma transporter with a therapeutic function that is derived from a membrane receptor. The present invention is exemplified by the description of new therapeutic agents that can be used in the treatment of Acquired Immunodeficiency Syndrome: hybrid macromolecules composed of albumin derivatives coupled to derivatives of the CD4 receptor having a normal or a higher affinity for the HIV-1 virus.
Patent EP-0385945-B1 (EP)
Title: Ski binding with a sole plate
IPC: A63C9/00
Filed: 1990-02-22
Granted: 1992-05-13
Abstract: Sole plate for a ski binding, mounted pivotably on the ski about a pivot (3) and equipped with guide means retaining the plate against the ski. These guide means comprise a metal plate (20) mounted slideably under a piece fixed to the ski, such as a bridging flange (21). The transverse opposite edges (20a, 20b) of this plate are engaged and slide in grooves of the sole plate (1). The traction force on the bridging flange is independent of the longitudinal position of the plate. Such a mounting is particularly advantageous for a sole plate in two parts (4, 7) which can be displaced relative to each other, one carrying the means (5) for holding the front part of the boot and the other a heelpiece (8). 
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Patent EP-0391884-B1 (EP)
IPC: C09J5/00
Filed: 1990-03-14
Granted: 1992-02-19
Abstract: For filling the edge groove (26) of an insulating glass pane (1) of an arbitrarily designed outer contour with sealing compound, stored geometrical data of the outer contour of the insulating glass pane (1) are utilized for controlling the relative motion between the insulating glass pane (1) and the filling nozzle (4). The relative velocity of the relative motion between the insulating glass pane (1) and the filling nozzle (4) is varied in such a way that the desired extent of filling of the edge groove (26) remains constant even in case of a change in the depth of the edge groove and/or in case of fluctuating feeding rate of a sealing compound. Furthermore, the relative speed between the filling nozzle (4) and the insulating glass pane (1) is selected to be higher in the zone of linear or less strongly curved sections (6) of the edge groove (26) than in the zone of more strongly curved sections (5). The delivery of the sealing compound to the filling nozzle (4) is performed via a conduit (46) guided through a hollow shaft (34) carrying the filling nozzle (4) so that the conduit (46) does not impede the rotatability of the filling nozzle (4).
Patent EP-0424490-B1 (EP)
Title: Verfahren und vorrichtung zur herstellung eines dreibasigen treibladungspulvers
Inventor: MOGENDORF KLAUS-DIETER
IPC: C06D5/00
Filed: 1990-04-17
Granted: 1995-03-08
Abstract: Die Erfindung bezieht sich auf ein Verfahren und eine Vorrichtung zur Herstellung von dreibasigem Treibladungspulver. Um einen betriebssicheren, kontinuierlichen Verfahrensablauf zu ermöglichen, ist erfindungsgemäß vorgesehen, daß in einem Scherwalzenwerk (1) zunächst ohne Lösungsmittel ein zweibasiges fertig gelatiniertes Zwischenprodukt aus Nitrozellulose und Sprengöl hergestellt wird. Das Zwischenprodukt wird granuliert und einem Extruder (4) zugeführt, in welchen der dritte kristalline Energieträger und Lösungsmittel eingebracht werden. Dort wird die Pulvermasse homogenisiert und zu lösungsmittelfeuchten Pulversträngen extrudiert.