Patent EA-003119-B1 (EA)
Title: Process and device for facilitating the implantation of biological material
Inventor: VALDES GONZALEZ RAFAEL
IPC: A61F2/06
Filed: 1999-12-14
Abstract: 1. A device for facilitating the implantation of biological material, wherein comprising a central, preferably tubular body, sealing means in the corresponding ends of said porous body, a plunger and sealing elements for the body of the device. 2. A device for facilitating the implantation of biological material, in accordance with claim 1, wherein the central body is a porous body, preferably based on a grid with a cylindrical shape, with mesh the size of 40 to 150 mesh and a diameter of 5 to 35 millimeters. 3. A device for facilitating the implantation of biological material, in accordance with claim 1, wherein the porous body contains sealing means in its ends which also have threaded connecting means, preferably of the female type for its assembly. 4. A device for facilitating the implantation of biological material, in accordance with claim 1, wherein the plunger consists of a cylindrical element with a diameter preferably of 4 to 25 millimeters. 5. A device for facilitating the implantation of biological material, in accordance with claims 1 to 4, wherein the sealing elements consist of a fastening sequin, a cylindrical joining section with a male type thread; and a concentric fastening section 1 to 5 millimeters in diameter. 6. A device for facilitating the implantation of biological material, in accordance with claims 1, 4 and 5, wherein the plunger is joined to or forms part of at least one of the sealing elements. 7. A device for facilitating the implantation of biological material, in accordance with claims 1 to 6, wherein the promoter device is made of a material that can be sterilized. 8. A device for facilitating the implantation of biological material to favor the implant of biological material, in accordance with claims 1 to 7, wherein the space between the plunger and the porous body varies in accordance with the thickness of the desired fibrocollagen tube from 1 to 15 millimeters. 9. Procedure for facilitating the implantation of biological material, comprising the steps of: implanting in the patient or individual a device to implant biological material; observing the formation or deposit of fibrocollagen around said device until a reservoir of neovascularized fibrocollagen is formed; and implanting, inside the reservoir of neovascularized fibrocollagen, cells and/or reagents producing the biological factor desired. 10. A procedure for facilitating the implantation of biological material, in accordance with claim 9, wherein the substance producing biological factors is a culture of live cells. 11. A procedure for facilitating the implantation of biological material, in accordance with claims 9 and 10, wherein the live cells are preferably islets of Langerhans. 12. A procedure for facilitating the implantation of biological material, in accordance with claims 9 to 11, wherein the substance producing biological factors contains Sertolli cells. 13. A procedure for facilitating the implantation of biological material, in accordance with the preceding claims, wherein comprising implanting in the body of the patient or individual the device for the formation of the tube or reservoir of fibrocollagen, removing the plunger inside the device once said tube or reservoir of neovascularized fibrocollagen has been formed, implanting the substance producing the biological factor desired, closing the tube or reservoir of neovascularized fibrocollagen with an element that will permit the existence of a space within said tube or reservoir of neovascularized fibrocollagen. 14. A procedure for facilitating the implantation of biological material, in accordance with claim 13, wherein the fibrocollagen tube that is formed can be used as a graft, preferably vascular, of the trachea, urethra or esophagus among others.