baber/WOPTO huggingface dataset:
Patent PT-653439-E (PT)
Inventor: HELSBERG MATTHIAS
IPC: C07H21/00
Filed: 1994-11-07
Abstract: Oligonucleotides (I) having at least one non-terminal pyrimidine nucleoside modified and additionally having the 5'- and/or 3'-terminal modified are new, with some specific exclusions. Oligonucleotides (I) having at least one non-terminal pyrimidine nucleoside modified and additionally having the 5'- and/or 3'-terminal modified are new, with the exception of oligonucleotides in which all of the nucleosides are modified and Cys asterisk -Ala-Cys-Cys-Ala asterisk -Ala-Cys-Cys-Thr asterisk -Cys-Thr-Thr-Cys asterisk -Cys-Ala-Cys-Ala-, Cys asterisk -Ala-Cys asterisk -Cys-Ala asterisk -Ala-Cys asterisk -Thr-Thr-Cys-Thr asterisk -Thr-Cys asterisk -Cys-Ala asterisk -Cys-Ala-, Cys-Ala asterisk -Cys-Cys asterisk -Ala-Ala asterisk -Cys-Thr asterisk -Thr-Cys asterisk -Thr-Thr asterisk -Cys-Cys asterisk -Ala-Cys asterisk -Ala- and Cys-Ala-Cys asterisk -Cys asterisk -Ala-Ala-Cys asterisk -Thr asterisk -Thr-Cys-Thr asterisk -Thr asterisk -Thr-Cys-Cys-Ala asterisk -Cys asterisk -Ala. An Independent claim is included for the preparation of (I) by chemical synthesis.
Patent PT-742789-E (PT)
Inventor: JANOFF ANDREW S
IPC: C07C211/45
Filed: 1995-02-02
Abstract: This invention provides a compound having the formula R<1>-Y<1>-CHZ<1>-CH(NY<2>Y<3>)-CH2-Z<2>, wherein: R<1> is a straight-chained alkyl, alkenyl or alkynyl group having from 8 to 19 carbon atoms in the aliphatic chain; Y<1> is -CH=CH-, -C PARALLEL C- or -CH(OH)CH(OH)-; Z<1> is OH or a conversion-inhibiting group; Z<2> is a conversion-inhibiting group; Y<2> is H, phenyl group, an alkylsubstituted phenyl group having from 1 to about 6 carbons in the alkyl chain, or an alkyl chain having from 1 to 6 carbons; Y<3> is H or a group having the formula -C(O)R<2> or -S(O)2R<2>; R<2> is a straight-chained alkyl, alkenyl, alkynyl group having from 1 to 23 carbon atoms in the chain; and when Z<2> is an amino, R<2> is an aliphatic chain having from 1 to 9 or from 19 to 23 carbon atoms in the aliphatic chain.
Patent PT-779082-E (PT)
Inventor: LECLERC OLIVIER
IPC: A62D101/43
Filed: 1996-11-14
Abstract: A treatment process for solid waste containing metals comprises: (i) mixing the waste with solid reducing agent; (ii) heat treating in a furnace at above 1000 degrees C to produce a glassy slag poor in metals and combustion gases rich in vapourised metals; (iii) cooling the gases by mixing them with air; filtering the product to recover the metals in form of salts which are further treated; (iv) and washing the gases before discharging them to the atmosphere.
Patent PT-817572-E (PT)
Inventor: ASHAUER KARIN
IPC: A21D13/08
Filed: 1996-03-04
Abstract: Bakery fat compositions, comprising: 90 - 98 wt.% of liquid oil, 0.5 - 5 wt.% of a hardened vegetable fat, having an IV < 20, 0.5 - 2 wt.% of an emulsifier, 0 - 2 wt.% of lecithin, 0.1 - 2,5 wt.% of a cold gelling thickener are particularly suitable for the preparation of cakes, provided with fruitpieces.
Patent PT-892127-E (PT)
Inventor: FISCHER WILLIBALD
IPC: E04G11/36
Filed: 1998-06-04
Abstract: The device forms predetermined cracking points on concrete components (2), and has an insert (8,8a,8b) which creates a reduction in the component cross section, and which is not permeable to concrete. The insert is arranged on a shuttering wall (3,3a,3b) which extends mainly across the cross section of the component, and which is made from a perforated material. The perforated wall is covered by the insert in a region (A) which corresponds to the required reduction of the cross section. The device may also be in the form of an element for shuttering a boundary surface between two concrete sections which are to be cast one after the other.
Patent PT-1011943-E (PT)
Inventor: PEDRINI LUIGI
IPC: B28D1/06
Filed: 1998-04-21
Abstract: The oscillating frame comprises a blade-holder frame (1) made to oscillate over the block (3) being machined by means of arms suspended on cursors (16) which slide in guides (18) in the columns (8) of the machine, a mechanism (2) to transmit reciprocating motion to the said frame (1), fixed cross-beams (9) to stiffen the columns, it presents a cross-beam (15, 27) joining the said cursors (16, 21, 26) and which is vertically mobile with them. In some versions, moreover, it presents: side members (60, 69, 84) for stiffening and joining the cursors (55, 65) or support structures (64, 67, 82) for the said suspension arms, which move vertically with them.
Patent PT-991330-E (PT)
Inventor: GERARD MCADAM KEVIN
IPC: A24B15/16
Filed: 1998-05-29
Abstract: The invention relates to a reconstituted smoking material which comprises a non-polyol aerosol generator, no tobacco, binder (optional) and inorganic filler. A further polyol aerosol generator may also be contained in the smoking material. There is also provided a smoking article containing such material in a conventional arrangement or with a core axially disposed within an annulus.
Patent PT-1029661-E (PT)
Inventor: WOLFGANG LOHWASSER
IPC: B32B15/08
Filed: 1999-11-24
Abstract: A laminated polymer film contains a metal layer as an adhesion promoter between the polymer film and a ceramic coating layer.  A laminated polymer film (10), optionally having a ceramic material (14) deposited on at least one face by means of a vacuum thin film coating process, has an extrusion coated polymer layer (18) applied to the polymer film or ceramic material (14) whereby the ceramic layer (14) is between the polymer film (12) and the extruded layer (18). A metal layer (16) of chromium, aluminum, nickel, titanium, iron, molybdenum or an alloy of these metals is applied between (12) and (14) as an adhesion promoter.  An Independent claim is included for a process for the production of the film (10) by deposition of the metal layer (16) by means of a vacuum thin film coating process onto the polymer film (12) and/or the ceramic layer (14) prior to extrusion coating.
Patent PT-1069912-E (PT)
Title: Injectable igf-formulations containing succinate as buffering agent
Inventor: SHIRLEY BRET A
IPC: A61K38/22
Filed: 1999-04-02
Abstract: The invention is directed to formulations of a pharmaceutically active agent for in vivo use. The formulations to which the invention is directed are designed to minimize the pain associated with components in injectable formulations, other than the pharmaceutically active agent. The invention is particularly directed to buffers that provide for minimum pain upon injection. Insulin-like growth factor I (IGF-I) is a preferred pharmaceutically active agent.
Patent PT-1127133-E (PT)
Inventor: EBERHARD HILDT
IPC: C07K14/02
Filed: 1999-11-03
Abstract: The present invention relates to a cell-permeable polypeptide that can mediate cell permeability to substances, DNA coding for said polypeptide and a method for the production of said polypeptide. The invention also relates to antibodies directed against the polypeptide and the use of said polypeptide in the mediation of cell permeability to substances.
Patent SG-75092-G (SG)
Title: Nitrogen-free esters of carboxy containing interpolymers
IPC: C08F8/14
Filed: 1992-07-21
Abstract: Nitrogen-free esters of a carboxy-containing interpolymer, wherein the interpolymer has an inherent viscosity ranging from about 0.05 to 1.5 are disclosed. The esters are useful as additives in functional fluids including transmission fluids (both automatic and manual), hydraulic fluids and gear fluids. The transmission, hydraulic and gear fluids containing the esters exhibit improved shear stability while maintaining desired high and low temperature viscosity characteristics.
Patent IE-32623-L (IE)
Title: Nitro-azacycloalkan-2-ones
IPC: C07D223/10
Filed: 1969-01-21
Abstract: 1,223,651. 1 - Formyl - 3 - nitro - azacycloalkan - 2 - ones. AGRIPAT S.A. 21 Jan., 1969 [22 Jan., 1968], No. 3355/69. Heading C2C. Novel 1 - formyl - 3 - nitro - azacycloalkan- 2-ones of Formula (I) in which A represents an alkylene radical, unsubstituted or substituted by one or more C 1-6 alkyl groups, having 4 to 10 carbon atoms in the chain, are prepared by reacting an azacycloalkanone of Formula (II) with a formylating agent consisting of an N-disubstituted formamide and an acid halogenating agent, in the presence of an organic aprotic solvent and/or diluent and nitrating the complex thus obtained at a temperature of from - 10 to + 30 C. and then hydrolysing it at a temperature below + 30 C. 3 - Benzylamino - azacycloheptan - 2 - one is prepared by saponifying 1-formyl-3-nitro-azacycloheptan-2-one to form 3-nitro-azacyclohepta-2-one, hydrogenating this to form 3- aminon - azacycloheptan - 2 - one and reacting this with benzaldehyde in the presence of hydrogen and Raney nickel.
[GB1223651A]
Patent IE-44219-L (IE)
Title: Clarification of water
IPC: C02F1/52
Filed: 1977-01-27
Abstract: 1509481 Clarification of waste water PATERSON CANDY INTERNATIONAL Ltd 16 Dec 1976 [27 Jan 1976] 03045/76 Heading C1C Water is clarified by adding a coagulant to raw water to form a floc, concentrating the floc into a sludge, treating the sludge with a polyelectrolyte to convert the sludge to a fast-settling granular form, and feeding the treated sludge into incoming raw water so that the treated sludge collects a fresh covering of microfloc particles.
[GB1509481A]
Patent IE-32127-L (IE)
Title: Pyridine derivatives
IPC: C07D213/61
Filed: 1968-04-08
Abstract: 1,157,186. Compositions containing pyridine-carboxylic acids. ASTRA A.B. 3 April, 1968 [26 April, 1967], No. 19174/67. Heading A5B. [Also in Division C2] Pharmaceutical compositions for lowering serum lipid concentration comprise a pyridine carboxylic acid 'of formula:- wherein n is 0 or 2 or 3 and R is hydrogen, halogen or -NH 2 , and is fluorine or chlorine when n is 0, or a non-toxic salt thereof, together with a pharmaceutically acceptable diluent or carrier. Suitable salts are those of Na or Ca. The compositions. may be for oral or parenteral adiministration, and may take the form of tablets or dragees, hard or soft gelatine capsules, sustained release tablets, effervescent tablets or powders, or a syrup or suspension. Sustained release tablets are either multi-layered, each layer having a slowly dissolving coating, or are formed by compressing into tablets, coated granules with slowly soluble coats of varying thickness, or consist of the active agent evenly distributed in a slowly soluble wax, fat or inert plastic matrix. Effervescent powders comprise the agent with a carrier of a suitable carbonate or bicarbonate (e.g. Na, Ca or K) and' a solid acid such as tartaric or citric acid, which powder, may be compressed into tablets The compositions may include vitamins and other active ingredients, e.g. Vitamins A, B 1 , B 2 , and B 6 , pantothenol and caffeine. The invention includes the preparation of the compositions by synthesis of the active agent (see Div. C2) followed by admixture with a carrier and' conversion into a pharmaceutical form.
[GB1157186A]
Patent IE-790433-L (IE)
Title: Solid fuel boiler
IPC: F24H1/44
Filed: 1979-05-28
Abstract: In a boiler 1, a lower part 3 of a combustion chamber 2 has vertical side wall portions 5, and an upper part 4 of the chamber has side wall portions 6 inclined inwardly with respect to the vertical side wall portions 5. A second chamber 24 is connected to the combustion chamber 2 by spaced-apart tubes 19, which extend upwardly from the combustion chamber 2 to the second chamber 24. The lower ends of the tubes 19 are located in a tube plate 20 forming the top of the combustion chamber and their upper ends are located in an upper tube plate 21 forming the bottom of the second chamber. The second chamber 24 has inwardly inclined side walls 26 and a top plate connectable to a flue. A water space 7, 22, 25 surrounds the combustion chamber 2, extends between the tube plates 20, 21 to surround each of the tubes 19, and surrounds the second chamber 24 so that heat from combustion is transferable through the side wall portions 5, 6 of the combustion chamber 2, the lower tube plate 20, the tubes 19 and the side walls 26 of the second chamber 24 to a liquid medium in the water space 7, 22, 25. <IMAGE>
[GB2053430A]
Patent IE-820529-L (IE)
Title: Static ram
IPC: G11C11/419
Filed: 1982-03-09
Abstract: PURPOSE:To achieve high speed readout of a high density static RAM, by changing gm of a bit line load according to a readout signal. CONSTITUTION:A sense amplifier SA differential amplifiers consisting of depletion type load transistors (TRs) Q13 and Q14 and enhancement driving TRs Q15 and Q16, and feedback TRs Q17 and Q18. Thus, a potential change on a bit line BL and the like in which a readout signal is transited from L to H level via feedback gate TRs Q11 and Q12 through rapid transition to H and L levels with the change in differential outputs DF and anti-DF' of the sense amplifier SA corresponding to the presence of change in the differential component on potentials DB and anti-DB' in response to the readout signal on a bit line BL and anti-BL', is extended with the charging of the TRQ11, allowing to make it equivalent thar the gm of a load TRQ5 on the bit line BL is tentatively increased, so that high speed readout is achieved.
[JP57150185A]
Patent IE-850829-L (IE)
Title: Tetrapeptide
IPC: A61K38/095
Filed: 1985-04-01
Abstract: The present invention relates to peptides having psychopharmacological properties, of the formula: <IMAGE> I wherein A represents the aminoacid residue Arg, Lys or Leu and R represents <IMAGE> as well as the functional derivatives thereof.
[US4623640A]
Patent IE-840977-L (IE)
Title: Pharmaceutical preparations
IPC: A61K31/455
Filed: 1984-04-19
Abstract: Pharmaceutical preparations comprising (a) co-dergocrine or a pharmaceutically acceptable acid addition salt thereof and (b) a calcium antagonist or a pharmaceutically acceptable salt thereof, as well as the treatment of hypertension/migraine by co-administration of components (a) and (b), e.g. in the form of a composition as defined.
[US4617306A]
Patent FI-850637-L (FI)
Inventor: MOYNE JOSE
IPC: B01J31/04
Filed: 1985-02-15
Abstract: p-Acyloxybenzene sulfonates, well suited for detergency applications, are facilely and rapidly prepared by acylating an alkali or alkaline earth metal, or ammonium p-phenol sulfonate, with an anhydride of a straight or branched chain carboxylic acid having from 7 to 12 carbon atoms, in a polar aprotic solvent and in the presence of a catalytically effective amount of an alkali or alkaline earth metal salt of a straight or branched chain aliphatic carboxylic acid having from 7 to 12 carbon atoms.
Patent IE-821222-L (IE)
Title: Bromosucrose derivatives
IPC: C07H5/02
Filed: 1982-05-21
Abstract: Compounds of the general formula (I) are potent sweeteners, especially 4,1',6'-tribromo-4,1',6'-trideoxygalactosucrose:   <IMAGE> (I)  in which R' represents a chlorine or bromine atom; R2 and R3 respectively represent a hydroxy group and a hydrogen atom or a hydrogen atom and a chlorine or bromine atom; R4 represents a chlorine or bromine atom; at least one of R', R3 and R4 representing a bromine atom.
Patent IE-36744-L (IE)
Title: Cephalosporin compounds as reagents
IPC: C07D501/22
Filed: 1972-10-06
Abstract: 1408391 Microbiological testing GLAXO LABORATORIES Ltd 22 Sept 1972 [7 Oct 1971] 46798/71 Heading C6F [ Also in Divisions C2 and G1] Enterobacter cloacae P99 and its mutant P99(M) cultured on agar are distinguished from one another by addition to each agar plate of a few drops of a solution of the cephalosporin derivative diphenyl methyl (6R, 7R)-3-(2,4 dinitrostyryl)-7-(2-thienyl-acetamido)-ceph-3-em- 4-carboxylate, when the colonies of P99 give a red colour while the colonies of P99(M) do not.
[GB1408391A]
Patent IE-901494-L (IE)
Title: Vascular endothelial cell growth factor
IPC: C12N15/16
Filed: 1990-04-26
Abstract: DNA isolates coding for a vascular endothelial cell growth factor may be used to produce the protein via recombinant expression systems. Such protein is useful therapeutically to treat conditions in which a selective action on the vascular endothelial cells, in the absence of excessive connective tissue proliferation, is desirable.
Patent IE-851501-L (IE)
Title: Electromagnetic screening
IPC: H05K5/03
Filed: 1985-05-24
Abstract: PCT No. PCT/SE85/00219 Sec. 371 Date Jan. 23, 1986 Sec. 102(e) Date Jan. 23, 1986 PCT Filed May 24, 1985 PCT Pub. No. WO86/00491 PCT Pub. Date Jan. 16, 1986.A sealing device in metal cabinets, which are used to screen off electromagnetic fields, for compressing metallic gaskets along the edges of its door. The device includes an elongate element (3,5,18) the length of which conforms with that of the door (1,2) and which is pivotable about an axis (7) parallel to the pivoting axis of the door. At its pivoting axis (7) the element is provided with a first elongate contact surface (10) which presses against the gasket (12) with a leverage effect when the element is turned to one end position. A second elongate contact surface (8) disposed on the element simultaneously engages against an abutment (9,16) to prevent the door from warping due to the pressure applied against the gasket.
Patent IE-801518-L (IE)
Title: Syringe
IPC: A61M5/178
Filed: 1980-07-22
Abstract: A syringe for dispensing medicaments includes a barrel with a discharge end and an open end for receiving a plunger. The plunger has a head with engagement means for receiving a plunger seal. The plunger seal is a tubular member which is severed along a generally longitudinal direction providing a slit which allows the seal to be expanded for fitting onto the plunger head. Preferably the slit has an irregularity at the forward end which provides a locking configuration which prevents the seal from being twisted away from its normally tubular shape. For metered dose application, the shank of the plunger may be threaded for the desired placement of a stop ring threaded on the shank. In one form, the ring and barrel have interlocking means to prevent the ring from moving backward when pressure is applied to the plunger after the ring has reached the barrel.
[US4246898A]
Patent IE-881543-L (IE)
Title: Phosphorus-containing hmg-coa reductase inhibitors and¹intermediates
IPC: C07F9/547
Filed: 1988-05-20
Abstract: Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents have the structure <IMAGE> including salts thereof, wherein R is OH, lower alkoxy or lower alkyl; R<x> is H or alkyl; X is -O- or -NH-; n is 1 or 2 Z is a hydrophobic anchor, such as <IMAGE> wherein the dotted lines represent optional double bonds. New intermediates used in preparing the above compounds, e.g. compounds in which the OH group is silane blocked, pharmaceutical compositions containing such compounds and a method for using such compounds to inhibit cholesterol biosynthesis are also provided.
[DE3817375A1]
Patent IE-41782-L (IE)
Title: Production of wired glass by rolling
IPC: C03B13/12
Filed: 1975-07-15
Abstract: 1513908 Rolled wired glass SOC ITALIANA VETRO SIV SpA 7 July 1975 [15 July 1974, 16 July 1974] 28490/75 Heading C1M Reinforcement wire (e.g. wire mesh) is fed into a glass melt, upstream of the forming rolls, at a rate higher than that of the glass issuing from the rolls until it forms a length of slack enough that it can freely float in the melt, whereby it is entrained without stress into the rolled glass, the feed rate then being adjusted to maintain the slack.
[GB1513908A]
Patent IE-902027-L (IE)
Title: Alkyleneindane derivatives
IPC: A61P11/00
Filed: 1990-06-06
Abstract: The present invention relates to compounds of formula (I), in which formula, n is 0 or 1, m is 0 or an integer from 1-7, R<1> and R<2> (which may be the same or different) stand for hydrogen or C1-C8-hydrocarbyl, or, taken together with the carbon bearing the hydroxyl group (starred in formula I), R<1> and R<2> can form a saturated or unsaturated C3-C8 carbocyclic ring. In addition, R<1> and/or R<2> and/or one of the m carbons designatedby the " DEG " may be optionally substituted with a hydroxyl group or one or more chlorine or fluorine atom(s); and finally one of the carbons designated " DEG " may optionally be substituted by one or two C1-C2 alkyl group(s); and derivatives of the compounds of formula I in which one or more hydroxy have been transformed into -O-acyl or -O-glycosyl or phosphate ester groups; such masked groups being hydrolyzable in vivo. The present compounds find use in both the human and veterinary practice in the treatment and prophylaxis of autoimmune diseases (including diabetes mellitus), hypertension, acne, alopecia, skin ageing, imbalance in the imune system, inflammatory diseases such as rheumatoid arthritis and asthma as well as diseases characterized by abnormal cell differentiation and/or cell proliferation, such as e.g. psoriasis and cancer.
Patent IE-42090-L (IE)
Title: Curable polyurethane-imide composition
IPC: C08G18/83
Filed: 1975-10-17
Abstract: A curable composition is provided which comprises A. an imide group-containing compound which is either A. A BIS-IMIDE OF THE FORMULA <IMAGE> (I) which D represents a radical of the formula <IMAGE> in which Y represents H, CH3 or Cl, m is O or 1, and A represents a divalent organic radical containing 2 to 30 carbon atoms, or B. A MIXTURE COMPRISING A BIS-IMIDE OF FORMULA (I) and a mono-imide of the formula <IMAGE> (II) in which D is as defined above and R represents a hydrogen atom or a monovalent organic radical containing from 1 to 20 carbon atoms; and B. a polyurethane elastomer, in amounts such that the weight ratio <IMAGE> IS FROM 1/5 TO 4/1. Such compositions are useful for preparing moulded articles, adhesives, laminates and coatings.
[US4085164A]
Patent IE-882315-L (IE)
Title: Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof
IPC: C07D207/42
Filed: 1988-07-28
Abstract: ARYLPYRROLE INSECTICIDAL. ACARICIDAL AND NEMATICIDAL AGENTS AND METHODS FOR THE PREPARATION THEREOF This invention is directed to certain novel insecticidal, acaricidal and nematicidal arylpyrrole agents and a method for controlling insects, acarids and nematodes therewith. The invention also is directed to a method for protecting growing plants from insect, acarid and nematode attack by applying to said plants or the soil in which they are growing, an insecticidally, acaricidally or nematicidally effective amount of a novel arylpyrrole compound. The present invention further is directed to a method for the preparation of the arylpyrrole compounds.
[CA1332060C]
Patent IE-852684-L (IE)
Title: Benzimidazole derivatives
IPC: C07D491/056
Filed: 1985-11-01
Abstract: Compounds of structure (I) <CHEM> and pharmaceutically acceptable salts thereof, in which R<5> and R<6> are the same or different and are each hydrogen, C1-6alkyl or C3-6cycloalkyl or together with the nitrogen atom to which they are attached form an acetidino, pyrrolidino, piperidino, piperazino, N-C1-4alkylpiperazino or morpholino group and one of R<7> and R<8> is halogen, and the other is hydrogen, halogen or C1-6alkyl; processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use as inhibitors of gastric acid secretion.
[EP0184322A1]
Patent IE-872985-L (IE)
Title: Contact lens manufacture
IPC: G02B1/04
Filed: 1987-11-05
Abstract: Contact lenses which are optically clear, hydrolytically stable, biologically inert, wettable, flexible, substantially non-swellable in aqueous ocular tear fluid, oxygen permeable of a block copolymer containing polysiloxane and polyoxyalkylene oxide units are disclosed, as well as the preparation thereof and methods of treating vision defects therewith.