baber/WOPTO huggingface dataset:
Patent AU-2017368331-A1 (AU)
Title: Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
Inventor: PORTS MICHAEL
IPC: A61K35/17
Filed: 2017-12-01
Abstract: The present disclosure relates to methods, compositions and uses involving immunotherapies and inhibitors of a target protein tyrosine kinase in which the kinase is not IL-2-inducible T cell kinase (ITK) and/or is selected from Bruton's tyrosine kinase (BTK), tec protein tyrosine kinase (TEC), BMX non-receptor tyrosine kinase (Etk), TXK tyrosine kinase (TXK) and/or receptor tyrosine-protein kinase ErbB4 (ErbB4). The provided methods, compositions and uses include administration of one or more such inhibitor with another agent, such as an immunotherapeutic agent targeting T cells and/or genetically engineered T cells, such as CAR-expressing T cells. Also provided are methods of manufacturing engineered cells, cells, compositions, methods of administration, nucleic acids, articles of manufacture and kits. In some aspects, features of the methods and cells provide for improved activity, efficacy, persistence, expansion and/or proliferation of T cells for adoptive cell therapy or endogenous T cells recruited by immunotherapeutic agents.
Patent WO-2019090392-A1 (WO)
Title: Dispositif, procédé et système d'imagerie optique
Inventor: CHENG SHAOKOON
IPC: G02B23/24
Filed: 2018-11-09
Abstract: L'invention concerne une sonde destinée à l'imagerie optique d'une voie et des procédés associés. La sonde comprend une série d'unités d'imagerie optique qui comprennent un diviseur de faisceau qui tourne autour d'un axe. Le diviseur de faisceau dirige une première partie de lumière de détection traversant un trajet de lumière à l'extérieur de la sonde dans une direction radiale sur une partie de paroi de la voie et fait passer une seconde partie de la lumière de détection vers une unité d'imagerie optique adjacente de la sonde. La lumière renvoyée par la partie de paroi de la voie est reçue et renvoyée le long du trajet de lumière.
Patent AU-2018200518-A1 (AU)
Title: Process for manufacturing glatiramer acetate product
Inventor: COHEN RAKEFET
IPC: A61K38/02
Filed: 2018-01-23
Abstract: Abstract The patent provides a process of preparing a pharmaceutical preparation of glatiramer acetate and mannitol in a suitable container comprising the steps of: (i) obtaining an aqueous pharmaceutical solution of glatiramer acetate and mannitol: (ii) filtering the aqueous pharmaceutical solution at a temperature of from above 0*C up to 17.50C to produce a filtrate; and (iii) filling the suitable container with the filtrate obtained after performing step (ii), so as to thereby prepare the pharmaceutical preparation of glatiramer acetate and mannitol in the suitable container. This patent further provides an aqueous pharmaceutical solution comprising 40mg/ml glatiramer acetate and 40mg/ml mannitol, wherein the aqueous pharmaceutical solution a) has a viscosity in the range of 2.0-3.5 cPa; or b) has an osmolality in the range of 275-325 mosmol/Kg. This patent also provides a prefilled syringe, an automated injector and a method of treatment of a human patient.
Patent AU-2018204157-A1 (AU)
Title: A low flow emitter with echelon shaped teeth
Inventor: DEFRANK MICHAEL PATRICK
IPC: B60L50/10
Filed: 2018-06-12
Abstract: An emitter, comprising: at least three distinct flow-paths, wherein the three distinct flow-paths are a front flow-path, a middle flow-path and a back flow-path; a plurality of holes, running along a first edge and a second edge of the emitter; and an echelon shaped teeth portion, running parallel to the first edge and the second edge, wherein the echelon shaped teeth portion at least partially extends between a first side and a second side, and a gap is provided between two consecutive teeth of the echelon teeth shaped portion to provide increased cross-section to open up the flow path. % 102 Figure 1
Patent AU-2018204454-A1 (AU)
Title: Lone worker fall detection
Inventor: NANJAPPAN EZHIL
IPC: G08B21/00
Filed: 2018-06-20
Abstract: A lone worker system for performing a safety check is provided. The lone worker system includes a mobile device. The mobile device includes a sensor and a memory storing a safety check application thereon and a processor. The processor is coupled to the memory and executes the safety check application under a motion mode including an active tracking of a fall motion event by the sensor. In response to the fall motion event being detected during the active tracking, the processor operates a count utilizing a timer of the safety check application. If the count exceeds a predetermined amount of time, the safety check application enters an emergency mode to execute an emergency alert. 210 Initiating a safety check application on a mobile device with respect to a service call 220 Detecting a location of the mobile device by the safety check application (and communicating location to a server) 230 Executing use-case safety monitoring by the safety check -- application and/or the server 240 Escalating the service call by the safety check application and/or the server
Patent AU-2018207620-A1 (AU)
Title: Method and system for repositioning a service location
Inventor: YU RYAN
IPC: H04W4/02
Filed: 2018-01-12
Abstract: A network computer service can receive a service request associated with a first service location. Additionally, the network computer service can detect a user action to associate the service request with a second service location. In some examples, the user input can be detected on a user device. In other examples, the second service location can be different from the first service location. Moreover, the network computer service can determine the second service location satisfies a predetermined permissibility criterion for permitting change of the first service location to the second service location. In response to determining the second service location satisfies the predetermined permissibility criterion, the network computer service can transmit an instruction to cause a device to associate the service request with the second service location in place of the first service location.
Patent AU-2018226393-A1 (AU)
Title: Edge protection system with intersection module
Inventor: MURDOCH THOMAS JAMES
IPC: E04F15/02
Filed: 2018-09-03
Abstract: ll:\txb\Interwoven\NRPortbl\DCC\TXB\15837159 l.docx-13102017 An edge protection system for use with concrete flooring, including an initial edge unit having a first part and a second part, the first part for coupling to an edge portion of a first concrete flooring panel and the second part for coupling to an opposed edge portion of a second, neighbouring, concrete flooring panel, the system also including an angled edge unit having a first part and a second part, the first part for coupling to another edge portion of the second concrete flooring panel and the second part for coupling to an opposed edge portion of a third, neighbouring, concrete flooring panel, and a modular intersection part at an intersection of the first to third panels, wherein the modular intersection part is adapted to be coupled to the initial edge unit with the initial edge unit extending radially from the modular intersection part in a first direction, and wherein the modular intersection part is adapted to be coupled to the angled edge unit with the angled edge unit extending radially from the modular intersection part in a second direction at an angle to the first direction..
Patent AU-2018226459-A1 (AU)
Title: Surfboard structure with fin assembly
Inventor: YEH TZONG IN
IPC: B63B35/79
Filed: 2018-09-06
Abstract: A fin assembly includes a fin body and a fin holder. The fin holder has an elongated channel, a pair of opposing slots, a pair of front guiding grooves and a pair of rear guiding grooves. The pair of front guiding grooves 5 are defined in the opposing sidewalls of a front section of the elongated channel at a horizontal level, and misaligned with a bottom of the elongated channel. The pair of rear guiding grooves are defined in the opposing sidewalls of a rear section of the elongated channel above the horizontal level, and are flush with the bottom of the elongated channel. Besides, the 10 fin holder defines in its rear wall a horizontal hole with a cross section large enough to cover a space between the pair of rear guiding grooves.
Patent AU-2018226494-A1 (AU)
Title: A Circulation System for Heating and Cooling
Inventor: BAI BING
IPC: F24S10/75
Filed: 2018-09-07
Abstract: Abstract A circulation system for heating and cooling, comprising: a heat exchange module; a first circulation system for heating water having the heat exchange module connected to a hot water storage tank; a second circulation system for heating and cooling having the heat exchange module connected to an energy storage tank; a control valve for switching and activating between the first circulation system and the second circulation system; wherein the energy storage tank comprises a first coiled piping connected to a water main; the hot water storage tank comprises a second coiled piping connect to a hot water system or another hot water terminal device; the first coiled piping is communicable to the second coiled piping; and the heat exchange module comprises a heat conduction panel and heat pipes which are contacting the heat conduction panel.
Patent AU-2018226611-A1 (AU)
Title: Method of scanning and assessing lung and vascular health
Inventor: SAMARAGE CHAMINA RAJEEV
IPC: A61B5/00
Filed: 2018-02-27
Abstract: The invention relates to a method of scanning for vascular ill health using a data set from an in vivo scan, the method including the steps of: (1) extracting blood vessel location data and blood vessel size data from the scan data set; (2) selecting a region in the extracted vessel location data; and (3) comparing the size data in the selected region to size data in a corresponding region of a normative data set to determine vascular health.
Patent AU-2018229408-A1 (AU)
Title: Valve Cusp Sizer
Inventor: OZAKI SHIGEYUKI
IPC: A61F2/76
Filed: 2018-09-10
Abstract: [Problem] To provide a valve cusp sizer which is small and easy to handle. 5 [Solution] The present invention relates to a valve cusp sizer 100 for determining the size of a valve cusp depending on the size of a cardiac valve. The valve cusp sizer 100 includes a front surface 10 formed in an arcuate surface form to be abutted against an organism, a back surface 20 positioned on an opposite surface side of the front 10 surface 10, and a pinching portion 30 protruding from the back surface 20. By removing a grip member and a grip member attachment portion from a conventional valve cusp sizer in this manner, and by forming the pinching portion 30 to be held by a clamp, tweezers, or the like, it is possible to dramatically miniaturize the valve cusp sizer while maintaining necessary functions of the valve cusp sizer.
Patent AU-2018253605-A1 (AU)
Title: Organ measuring tool assembly
Inventor: SRINIVASA MURTHY ARAVALLI AVVLN
IPC: G01B3/38
Filed: 2018-10-26
Abstract: ORGAN MEASURING TOOL ASSEMBLY An organ measuring tool assembly (10) is provided that includes a grasping device (12) and a measuring device (14) including a plurality of measuring components (30, 32) for measuring the size of an internal body organ such as the bowel during an ostomy procedure. The plurality of measuring components (30, 32) have different and can be removably coupled to the grasping device (12). By measuring the bowel prior to performing an ostomy procedure, the appropriate size openings can be formed in the muscle layer of the abdominal wall, i.e., the rectus sheath, to minimize complications associated with ostomy. Ccc cwh3 C.it It " < I 'I
Patent AU-2018254636-A1 (AU)
Title: Rock bolt installation tool
Inventor: BERGHORST ADRIAAN
IPC: E21D20/00
Filed: 2018-03-23
Abstract: A tool to aid in the installation of a rock bolt assembly in a rock hole which includes a drive shaft having a proximal end, which is adapted to engage with a drilling rig, and a distal end which includes a recess which is adapted to receive a trailing end portion of the rock bolt and which has a first seat against which an axially pre-set component of the rock bolt assembly abuts, a tubular sleeve telescopically engaged with the shaft which has a first end, which is adapted to receive an axially moveable component of the rock bolt assembly and which has a second seat against which the axially moveable component abuts, and a second end, wherein the sleeve is reciprocally moveable relatively to the shaft between a biased forward position in which the axially pre-set component and the axially moveable component are spaced, and a retracted second position in which the axially pre-set component engages or connects to the axially moveable component.
Patent AU-2018267608-A1 (AU)
Title: Chisel cut staples for use in surgical staplers and a method for manufacturing surgical staples
Inventor: PENNA CHRISTOPHER P
IPC: A61B17/064
Filed: 2018-11-21
Abstract: CHISEL CUT STAPLES FOR USE IN SURGICAL STAPLERS AND A METHOD FOR MANUFACTURING SURGICAL STAPLES A surgical staple (10) includes first and second legs (20) that are interconnected by a backspan (30). Each of the first and second legs (20) defines a longitudinal leg axis (L) and extends from the backspan (30) along the leg axis (L) to a tip (22). The tip (22) is sharpened such that the tip (22) is symmetrical about a longitudinal leg plane that includes the leg axis (L). In addition, a method of manufacturing a surgical staple (10) includes sharpening a tip (22) of a leg (20) of the surgical staple (10) such that the tip (22) is symmetrical about a longitudinal leg axis (L) that includes a longitudinal leg axis (L) of the leg (20). 29a 20 ( 22 12 2b2 FIG.11 FIG. 12 29b L 28b 29 8 28b >26 22 I 28a 29a 28a 29a FIG. 13 FIG. 14
Patent AU-2018314195-A1 (AU)
Title: System and method for interference reduction in radio communications
Inventor: PEARCE STEPHEN
IPC: H04L27/00
Filed: 2018-07-30
Abstract: This disclosure provides a system and method for separating a first signal from a second signal of a plurality of constituent signals within a composite signal. The method can include receiving a first portion of the composite signal at a first clock rate and exponentiating it to detect the first signal and the second signal within the composite signal and determine modulation estimates of the first and second signals and at least one symbol rate. The method can include resampling the first portion based on the modulation estimates at x-times the symbol rate to determine symbol trajectory, modulation type, and offset information between the first and second signals. The method can include determining a synthesized first signal and a synthesized second signal representing the first signal and the second signal within the first period of time at a second clock rate that is a multiple of the first clock rate.
Patent AU-2018319128-A1 (AU)
Title: Ethane oxidative dehydrogenation
Inventor: CALVO LAURA MARIEL
IPC: C07C11/04
Filed: 2018-08-02
Abstract: The invention relates to a process for oxidative dehydrogenation of ethane, comprising the steps of:(a) subjecting a stream comprising ethane to oxidative dehydrogenation conditions;(b) removing water from at least part of the effluent resulting from step (a);(c) optionally removing unconverted oxygen and/or carbon monoxide and/or ycetylene from at least part of the stream comprising ehtylene, unconverted ethane, carbon dioxide, optionally unconverted oxygen, optionally carbon monoxide and optionally acetylene resulting from step (b);(d) removing ethylene from at least part of the stream comprising ehtylene, unconverted ethane and carbon dioxide resulting from step (b) or (c) by a complexation separation method;(e) partially and selectively removing carbon dioxide from at least part of the stream comprising unconverted ethane and carbon dioxide resulting from step (d);(f) recycling at least part of the stream comprising unconverted ethane and carbon dioxided resulting from step (e) to step (a).
Patent AU-2018320963-A1 (AU)
Title: Adhesive articles permitting damage free removal
Inventor: KRULL BRETT P
IPC: C09J7/00
Filed: 2018-08-24
Abstract: The present disclosure provides adhesive articles that can be removed from surfaces without damage by having reduced or eliminated contribution of a core backing to peel force generated by the adhesive during removal. In some instances, this can be accomplished by a core that loses structural integrity in a direction normal to a plane defined by a major surface. In other instances, the contribution is reduced by compromising the interface between the core and a peelable adhesive layer.
Patent AU-2018345807-A1 (AU)
Title: Methods of detecting transthyretin
Inventor: SALMANS JOSHUA REGINALD
IPC: A61K31/192
Filed: 2018-10-05
Abstract: The invention provides methods of detecting transthyretin (TTR) using a capture antibody and a reporter antibody. The capture antibody binds preferentially to misfolded TTR over native tetrameric form of TTR. The capture antibody binds to an epitope within amino acid residues 89-97 or TTR or to an epitope within amino acid residues 101-109 of TTR. 9D5 and 18C5 are examples of suitable capture antibodies. The methods can be used for diagnosing diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (
Patent AU-2018354785-A1 (AU)
Title: Substituted imidazopyridine amides and use thereof
Inventor: MEIBOM DANIEL
IPC: C07D519/00
Filed: 2018-10-18
Abstract: The application relates to novel substituted imidazopyridine amides of formula (I), to methods for the production thereof, to the use thereof alone or in combination for the treatment and/or prophylaxis of disorders, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of disorders, in particular for the treatment and/or prophylaxis of cardiovascular disorders, neurological and central nervous system and metabolic disorders
Patent AU-2018356527-A1 (AU)
Title: Floating wave energy device
Inventor: TOURNERIE VINCENT
IPC: F03B13/18
Filed: 2018-10-25
Abstract: Floating wave energy device intended to be installed in an aquatic medium comprising a surface S, water E and a bottom F, produced by a cylinder (10) comprising means for generating energy, and connecting means connected to anchors (30-1) and (30-2), characterized in that the connecting means (20) are crossed.
Patent AU-2018373510-A1 (AU)
Title: Method and apparatus for treating diplopia and convergence insufficiency disorder
Inventor: KOZIAK JOSEPH
IPC: A61B3/113
Filed: 2018-11-26
Abstract: A method of assessing a presence and/or severity of at least one of diplopia and convergence insufficiency disorder of a patient; it includes providing a patient with an image pair configured to present a first image to a first eye of the patient and a second image to a second eye of the patient; obtaining performance information of the patient when the patient performs a task requiring the perceiving of the information content of the first image and the information content of the second image; adjusting, based on the performance information, the difference of the at least one image parameter between the first image and the second image; and assessing the degree of at least one of the diplopia and convergence insufficiency disorder of the patient based on performance information of the patient when the patient performs the task following the adjusting.
Patent AU-2018378934-A1 (AU)
Title: Methods and systems for identifying progenies for use in plant breeding
Inventor: CHAVALI SRINIVAS PHANI KUMAR
IPC: G06N99/00
Filed: 2018-12-07
Abstract: Exemplary methods for identifying progenies for use in plant breeding are disclosed. One exemplary computer-implemented method includes accessing a data structure including data representative of a pool of progenies and determining a prediction score for at least a portion of the pool of progenies based on the data included in the data structure. The prediction score indicates a probability of selection of the progeny based on historical data. The method further includes selecting a group of progenies from the pool of progenies based on the prediction score, identifying a set of progenies, from the group of progenies, based on at least one of an expected performance of the group of progenies and at least one factor associated with the set of progenies, the pool of progenies and/or the group of progenies, and directing the set of progenies into a validation phase of a breeding pipeline.
Patent AU-2018392161-A1 (AU)
Title: Method for liquefying a natural gas stream containing nitrogen
Inventor: PARADOWSKI HENRI
IPC: F25J3/02
Filed: 2018-12-17
Abstract: A method for liquefying a natural gas feed stream comprising the following steps: Step a): Cooling the feed gas stream in order to obtain a liquefied natural gas stream at a temperature T1 and a pressure P1b; Step b): Introducing the stream from step a) into a denitrogenation column at a pressure P2 and a temperature T2 lower than T1 in order to produce, at the bottom, a denitrogenated liquefied natural gas stream and, at the head, a nitrogen-enriched vapour stream; Step c): Condensing the nitrogen-enriched vapour stream from step b) in a heat exchanger in order to produce a two-phase stream; Step d): Introducing the two-phase stream from step c) into a phase separator vessel in order to produce a liquid stream and a nitrogen-enriched gas stream; characterised in that at least part of the liquid stream from step b) is used during step c) to cool the vapour stream from step b) in said heat exchanger.
Patent AU-2018400796-A1 (AU)
Title: Keyway tie
Inventor: MATTSON STEVEN R
IPC: E01B9/38
Filed: 2018-12-20
Abstract: A tie having a non-linear keyway under the overlying rail to provide support to restrain lateral and longitudinal movement of the rail. A fastening system to hold rails down on a tie comprises a rail plate that may be fastened to the tie within the keyway. The fasteners are protected to avoid damage in case of a derailment or other adverse conditions. Also disclosed are visual inspection mechanisms to assist with determining whether a fastening system is securely attached to the tie.
Patent AU-2018454271-A1 (AU)
Title: Articles comprising indolenaphthopyrans
Inventor: STAYSHICH RYAN
IPC: C07D491/052
Filed: 2018-12-21
Abstract: Provided is an article which transitions from a first state to a second state in response to actinic radiation. The article includes an indolenaphthopyran, wherein in the first state the article exhibits a percent transmission of greater than 80 percent, and in the second state the article exhibits a percent transmission of between 35 and 75 percent, and a τ
Patent AU-2019200033-A1 (AU)
Title: A pharmaceutical combination and method for regulation of tumor microenvironment and immunotherapy
Inventor: CHEN JIA-SHIONG
IPC: A61K31/19
Filed: 2019-01-03
Abstract: G74330/US8498 A PHARMACEUTICAL COMBINATION AND METHOD FOR REGULATION OF TUMOR MICROENVIRONMENT AND IMMUNOTHERAPY Abstract of the Disclosure The invention relates to a method of removing immune suppression in a tumor microenvironment or stimulating an immune system against cancer cells, comprising administering to a subject a combination of a HDAC inhibitor and an NSAID in combination with an immune checkpoint inhibitor.
Patent AU-2019201628-A1 (AU)
Title: User interface for manipulating user interface objects
Inventor: ZAMBETTI NICHOLAS
IPC: G06F3/0362
Filed: 2019-03-08
Abstract: The present disclosure relates to user interfaces for manipulating user interface objects. A device, including a display and a rotatable input mechanism, is described in relation to manipulating user interface objects. In some examples, the manipulation of the object is a scroll, zoom, or rotate of the object. In other examples, objects are selected in accordance with simulated magnetic properties.