baber/WOPTO huggingface dataset:
Patent DE-60321865-D1 (DE)
Inventor: RIEPING MECHTHILD DR
IPC: C07K14/245
Filed: 2003-07-04
Granted: 2008-08-14
Abstract: The invention relates to a process for the fermentative preparation of L-amino acids, in particular L-threonine, in which the following steps are carried out:  a) fermentation of the microorganisms of the Enterobacteriaceae family which produce the desired L-amino acid and in which the rseB gene or nucleotide sequences which code for it are enhanced, in particular over-expressed, b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and c) isolation of the desired L-amino acid  <IMAGE>
Patent DE-60325910-D1 (DE)
Inventor: OTTO MARCIN JAN
IPC: B60C9/00
Filed: 2003-01-25
Granted: 2009-03-05
Abstract: The invention pertains to an aramid cord with high fatigue resistance comprising multifilament aramid yarn, obtained by the steps comprising: 
a) spinning a solution of an aromatic polyamide into a coagulation bath; 
b) optionally neutralizing and washing the resulting multifilament yarn; 
c) treating the yarn on-line with a curable epoxy compound, optionally together with or followed by treating the yarn with at least one alkaline curing agent; 
d) obtaining the yarn having a free epoxide content of not more than 10 mmoles/kg; 
e) converting the yarn to the cord; 
f) treating the cord with a curable epoxy compound; followed by 
g) treating the cord with a coating which is adhesive to rubber and rubber-like materials and different from the curable epoxy compound.  The invention further relates to fiber reinforced objects, such as tires, comprising said cord.
Patent DE-60326750-D1 (DE)
Inventor: GARBE JOACHIM CHRISTOPH HANS
IPC: G06F21/75
Filed: 2003-11-13
Granted: 2009-04-30
Abstract: In order to further develop a circuit arrangement ( 100 ) for electronic data communication, comprising-at least a non-volatile memory module ( 10 ) for storing data, and-at least an interface logic ( 20 ) associated with the memory module ( 10 )-for addressing the memory module ( 10 ) and-for writing data to the memory module ( 10 ) or-for reading data from the memory module ( 10 ), together with a related method for registering light attacks on the non-volatile memory module ( 10 ), in such a way that, firstly, the light attack is recognized immediately and reliably regardless of whether an access, in particular a read access, to the memory module ( 10 ) is taking place or not and, secondly, the entire address space of the memory module ( 10 ) is covered as uniformly as possible in this regard, it is proposed that at least a monitoring arrangement ( 22 ) provided for monitoring the memory module ( 10 ) is associated with the interface logic ( 20 ), by means of which monitoring arrangement ( 22 ) an irradiation of the memory module ( 10 ) with at least a light source [so-called "light attack"] can be detected and/or registered and/or signaled in a test mode (T) in which no write or read access to the memory module ( 10 ) takes place.
Patent DE-60327082-D1 (DE)
Inventor: NEUBAUER ANTONIE
IPC: C12N5/06
Filed: 2003-07-16
Granted: 2009-05-20
Abstract: The present invention relates to the field of animal health and in particular of Equine Herpes Viruses (EHV) wherein the gene encoding the protein gM is absent, and which is free of heterologous elements. Further aspects of the invention relate to pharmaceutical compositions comprising said viruses, uses thereof, and methods for the prophylaxis and treatment of EHV infections. The invention also relates to pharmaceutical compositions comprising the combination of EHV-1 and EHV-4 viruses wherein the gene encoding the protein gM is absent and which is free of heterologous elements.
Patent DE-60327888-D1 (DE)
Inventor: HUFFMASTER MICHAEL ARTHUR
IPC: F16L55/04
Filed: 2003-12-19
Granted: 2009-07-16
Abstract: The invention relates to a method for reducing vibrations in a conduit through which a gas-liquid mixture flows, the conduit having a certain wetted surface area, in which method the wetted surface area of at least part of the conduit is enlarged at least 2 times, preferably at least 6 times, more preferably at least 12 times, by providing the conduit over at least part of its length with an insert. The invention further relates to a vertical feed supply conduit, debouching into the feed inlet of a gas-liquid contact column, the gas-liquid contact column comprising a gas outlet, a liquid outlet and a feed inlet, wherein the vertical feed conduit comprises a vibration reducing insert, by which insert the wetted surface area of the conduit is enlarged as above described.
Patent DE-60328775-D1 (DE)
Inventor: KORETSKY DMITRY
IPC: B65G69/24
Filed: 2003-05-07
Granted: 2009-09-24
Abstract: A foldable wheelchair ramp is disclosed having a mountable base, a first ramp section and a second ramp section. In an extended configuration, the first and second ramp sections form a single, continuous ramp for facilitating wheelchair access to vehicles. For convenient storage, the first and second ramp sections fold with respect to each other and preferably retract into the vehicle floor such that, in the folded configuration, the top surface of the second ramp section lies substantially in the same plane as the vehicle floor. A linking assembly is provided to facilitate and control the folding of the ramp sections. For safety purposes, the ramp also includes a lid that covers the gaps between the ramp and the vehicle floor when the ramp is in an extended position.
Patent DE-60334711-D1 (DE)
Inventor: SCHAFFNER CARL P
IPC: A61K31/397
Filed: 2003-07-30
Granted: 2010-12-09
Abstract: A method of prevention or treatment of a cholesterol-associated tumor is provided which comprises administering a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe (SCH 58235) and/or its phenolic glucuronide, or at least one ezetimibe analog, e.g., SCH 48461 and SCH 58053, to a patient wherein the patient is either at risk of developing a cholesterol-associated tumor or already exhibits a cholesterol-associated tumor. Formulations of ezetimibe are also provided for the prevention or treatment of a cholesterol-associated tumor further comprising at least one other anticancer agent. An article of manufacture is also provided which comprises a container, instructions, and a composition, wherein the composition comprises a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe or its phenolic glucuronide, and the instructions are for the administration of the composition for the prevention or treatment of a cholesterol-associated tumor.
Patent DE-60336142-D1 (DE)
Inventor: VUKMIROVIC ANDREJA
IPC: A61K47/34
Filed: 2003-07-14
Granted: 2011-04-07
Abstract: The present invention provides a new stable pharmaceutical composition of erythropoietin (EPO) that is stabilized with a combination of a poloxamer polyol and a polyhydric alcohol.
Patent DE-68905613-D1 (DE)
Inventor: NYSTROEM CHRISTER
IPC: A61K47/00
Filed: 1989-01-12
Granted: 1993-05-06
Abstract: The invention relates to an ordered mixture of particles of a water-soluble, pharmaceutical carrier substance and smaller particles of at least one pharmaceutically active substance which adhere to the carrier particles. In accordance with the invention a pharmaceutical disintegrant is incorporated in the carrier particles. The invention also relates to pharmaceutical preparations which include one such ordered mixture, and also to a method of producing such preparations and to the use of the ordered mixtures in such preparations.
Patent DE-68906447-D1 (DE)
Inventor: DAVID MARIE-HENRIETTE L
IPC: C12N11/00
Filed: 1989-02-28
Granted: 1993-06-17
Abstract: 6-C8 to C22 acyl-1-C3 to C12 alkylglucosides are a new group of surface active compounds useful in particular as emulsifiers in cosmetics, pharmaceutical compositions and foodstuffs. They are prepared by reacting a 1-C3 to C12 alkyl glucoside with a C8 to C22 fatty acid in the presence of a lipolytic enzyme and in a reaction medium containing at most 30% and preferably 0.01 to 5% water.
Patent DE-68910922-D1 (DE)
Inventor: OLSSON KNUT GUNNAR
IPC: A61K31/495
Filed: 1989-09-19
Granted: 1994-01-05
Abstract: Heterocycles of formula (I) and their pharmacologically active salts are new, R1 = H, or halo; R2 = halo; X = 0, S or CH2; R3 and R4 = H or lower alkyl; n = 2-3; A = 2-pyrimidyl substd by R5 (gp (a)); 2-pyridyl substd by R6 and R7 (gp (b)); or 3-pyridyl substd by R6 and R7 (gp (c)); R5 = H, lower alkyl or halo; R6 and R7 = H, halo, lower alkyl, electron donor gp eg lower alkoxy or 0H, electron acceptor gp eg CN, N02, CF3, C00R8, C0NR9R10 or C0B; R8 = H or lower alkyl; R9 and R10 = H, lower alkyl or cycloalkyl; B = morpholino substd by R11 (gp (d)), or a gp of formula (e); m = 1-4; R11 = H or lower alkyl, lower = 1-5C.
Patent DE-68916385-D1 (DE)
Inventor: BOONE THOMAS C
IPC: A61K9/00
Filed: 1989-12-18
Granted: 1994-07-28
Abstract: A stable pharmaceutically acceptable formulation containing a pharmaceutically acceptable amount of a protein is disclosed. Also disclosed are associated means and methods for preparing such formulations.
Patent DE-68921389-D1 (DE)
Inventor: POPESCU MIRCEA C
IPC: A61K9/127
Filed: 1989-08-25
Granted: 1995-04-06
Abstract: An influenza immunizing dosage form comprising a liposome and an antigen of Influenza, particularly the hemagglutinin or bromelain fragment, wherein said liposome and antigen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt form of an organic acid derivative of a sterol and an antigen wherein said organic acid derivative of a sterol and antigen are present in an immunization dose, and method of use. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristolyphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an antigen wherein said DMPC/cholesterol and antigen are present in an immunization dose, and method of use.
Patent DE-68924347-D1 (DE)
Inventor: MATSON STEPHEN
IPC: C12N11/02
Filed: 1989-04-06
Granted: 1995-10-26
Abstract: This invention relates to novel compositions of matter and their methods of preparation, which compositions are esters with enhanced water solubility, for use in aqueous enzymatic resolution reactions of racemic mixtures of these esters. The importance of the production of the separate chiral isomers of the racemic mixtures resides in the isolation of the isomers which frequently have different biological activities. Of particular significance regarding the water soluble esters of this invention is that they are derivatized with groups which enhance their aqueous solubility and their reactivity with this invention's novel enzymatic resolving methods which are mediated in an aqueous environment.
Patent DE-68924501-D1 (DE)
Inventor: DUTTON PATRICK FRANCIS
IPC: G06F12/0888
Filed: 1989-04-18
Granted: 1995-11-16
Abstract: A storage subsystem for use in a data processing system having real and extended storage, a vector processor and a store-in cache buffer. Transfers between real and extended storage are performed with a store buffer external to the cache, but comparable in size to the line size of the cache directly associated with the real storage. Hard data errors in the cache are corrected with hardware invert-retry mechanism which operates in response to a machine check ard does the correction as a part of the instruction retry. Vector processor storage operations bypass the cache and transfer data directly from storage to the vector processor.
Patent DE-69003726-D1 (DE)
Inventor: HOLROYD TREVOR JAMES
IPC: G01R31/00
Filed: 1990-03-09
Granted: 1993-11-11
Abstract: The invention relates to a method and apparatus for testing the response of a stress wave sensor (10) to confirm that the transducer (12) and amplifier (20) are functioning satisfactorily. A pulser (24) is connected to the stress wave sensor (10) at a point between the transducer (12) and the amplifier (20). The pulser (24) supplies a first and a second electrical pulse in series to the stress wave sensor (10). The first electrical pulse has a large amplitude such that it causes an operative transducer (12) to oscillate and produce an additional electrical pulse. The first electrical pulse and the additional electrical pulse are supplied to the amplifier (20). An operative amplifier amplifies the first electrical pulse and any additional pulse to give an output signal, the output signal indicates if either the transducer or amplifier are not operating satisfactorily, The lack of an output signal indicates the amplifier is inoperative. The second electrical pulse has a predetermined amplitude and is supplied to the amplifier, and is amplified by an operative amplifier to give a measure of the gain of the amplifier.
Patent DE-69017172-D1 (DE)
Inventor: AUDAIRE LUC
IPC: H04N5/372
Filed: 1990-12-27
Granted: 1995-03-30
Abstract: An image (30) moves over a matrix of detectors (12) whose reading circuits (22) and electronic circuits for scanning the columns and the rows are produced by CTD type structures. Each circuit for scanning columns of a row of detectors includes a part integrated beside the detectors, with a spacing less than or equal to that of the rows of detectors. The movement takes place in a direction perpendicular to the columns of detectors and in two successive and opposite senses. The circuit (64) for scanning rows delivers a signal representing the image for each sense of movement of the image. 
<IMAGE>
Patent DE-69017917-D1 (DE)
Inventor: MADSEN HENNING
IPC: A47F5/01
Filed: 1990-11-13
Granted: 1995-04-20
Abstract: A sales shelf of the type being mountable optionally in a horizontal position, with a high rear wall portion (10) and with a front edge (8) having fixtures (9) for sign plates (12), and in an inverted forwardly and downwardly inclined position, in which the rear wall portion constitutes a high front wall. According to the invention also this wall portion is provided with fixtures (9) for the sign plates, such that the same sign plates can be used in both situations.
Patent DE-69022073-D1 (DE)
Inventor: SESSLER JONATHAN
IPC: C01B13/02
Filed: 1990-12-21
Granted: 1995-10-05
Abstract: The present invention includes a method to produce singlet oxygen from molecular oxygen generated by reaction with a sapphyrin compound excited at an absorbing wavelength to form a triplet species. Specifically, the sapphyrin compound is an alkylated sapphyrin, most preferably diprotonated 3,8,12,13,17,22-hexaethyl-2,7,18,23-tetramethylsapphyrin. Generation of the triplet species may be accomplished in an organic solvent, of which the most preferable solvents are chloroform, methanol or acetonitrile. Also encompassed within the present invention is a method to selectively produce singlet oxygen in an aqueous environment. A sapphyrin compound is incorporated within a membranous vesicle, the vesicle is illuminated with exciting light and the resultant excited triplet state sapphyrin compound reacts with molecular oxygen to produce singlet oxygen. Singlet oxygen was not generated external to the vesicle where the sapphyrin compound is present in an aqueous medium.
Patent DE-69032957-D1 (DE)
Inventor: THORSTEINSON ERLIND MAGNUS
IPC: C07D301/10
Filed: 1990-10-17
Granted: 1999-04-01
Abstract: Catalysts for the epoxidation of alkene, especially ethylene, to the corresponding alkylene oxide, e.g., ethylene oxide, which catalysts contain a high silver content on carriers having a high surface area and a high pore volume are disclosed. Methods for making and using such catalysts are also disclosed.
Patent DE-69033949-D1 (DE)
Inventor: GEFTER L
IPC: C07K14/47
Filed: 1990-11-02
Granted: 2002-05-23
Abstract: A substantially pure, covalently linked human T cell reactive feline protein (TRFP) of approximately 40,000 MW has been isolated from vacuum bag extract obtained by affinity purification of house dust collected from several homes with cats; DNA encoding all or a portion of the TRFP or peptide; compositions containing such a protein or peptide or portions thereof; and antibodies reactive with the TRFP or peptide are disclosed. Also disclosed are recombinant TRFP or peptide; modified or mutated TRFP peptides; their use for diagnostic or therapeutic purposes.
Patent DE-69108913-D1 (DE)
Inventor: CARINI DAVID
IPC: A61P9/12
Filed: 1991-07-15
Granted: 1995-05-18
Abstract: Angiotensin II antagonist antihypertensive compounds such as  <IMAGE> where R2 is -CHO or -COOH and R1 is ethyl have outstanding orally potency.
Patent DE-69109107-D1 (DE)
Inventor: MAYNE ALFRED
IPC: F04B1/04
Filed: 1991-05-22
Granted: 1995-05-24
Abstract: PCT No. PCT/AU91/00224 Sec. 371 Date Nov. 13, 1992 Sec. 102(e) Date Nov. 13, 1992 PCT Filed May 22, 1991 PCT Pub. No. WO91/18188 PCT Pub. Date Nov. 28, 1991.A machine that converts between reciprocating motion of a piston and rotary motion of a shaft. The shaft rotates an integral web that carries a number of lobe wheels spaced evenly about a pitch circle centered on the shaft. The lobe wheels are planetary driven by pinions and a fixed ring gear. The lobe wheels are somewhat star shaped with radially extending lobes which push followers outwardly, then release them inwardly, as the lobe wheels orbit past and below the follower. The follower is connected by a lever and a pair of connecting rods and to the piston.
Patent DE-69115027-D1 (DE)
Inventor: STOLL DONALD
IPC: B65G45/16
Filed: 1991-01-04
Granted: 1996-01-11
Abstract: A belt scraper which has first and second pairs of scraper support arms as well as first and second actuator arms for each of the support arms, and includes a gear adjustment by which the position of the belt scrapers may be adjusted with respect to the belt and with respect to the actuator arms, from a convenient position alongside of the belt.
Patent DE-69118661-D1 (DE)
Inventor: FRANCKE KURT
IPC: A47K13/00
Filed: 1991-11-08
Granted: 1996-05-15
Abstract: An arrangement for detachably holding seats (2) to the bowls of water-flushed toilets and comprising a number of arms (10) which can be adjustably attached to the underside of the seat (2). The free outer ends of the arms (10) are provided with pins (11) which can be locked in positions against the outside of the bowl rim of the toilet when the seat (2) is placed in position on the bowl. The arms (10) are pivotally mounted and can be locked in selected positions. The pins (11) are provided with a sleeve (12) of rubber or plastic material which generates a fricfional force in contact with the toilet bowl. The arms (10) pivot around a screw (19) which is screwed into the underside of the toilet seat (2) and which in one position enables the arm (10) to be adjusted positionally and in another position locks the arm. The head (20) of the screw (19) is preferably covered with a coating (23) of rubber or plastic material and forms a cushion which rests on the toilet bowl when the toilet seat (2) is in its position of use. <IMAGE>
Patent DE-69120035-D1 (DE)
Inventor: ROS ERIC
IPC: B65D90/00
Filed: 1991-12-06
Granted: 1996-07-11
Abstract: The container is characterised in that it has lateral extensions by opening out, corner uprights (7) having a retractable integrated strut (51) for lateral extension, support and lifting, as well as a lower base-frame structure (11) having, on its soffit (under-face) bearing and guiding means enabling it to be moved over a plane or a carrier track of a vehicle intended to transport it. 
<??>The invention is of interest to manufacturers of shelters for special use and of dwellings: worksites, camps, life-supporting bases etc. 
<IMAGE>
Patent DE-69125788-D1 (DE)
Inventor: MORIN JEAN-XAVIER
IPC: B01J8/00
Filed: 1991-11-04
Granted: 1997-05-28
Abstract: Cyclone for separating, by centrifuging, a mixture of gas and solid particles into a particle-enriched fraction and a particle-depleted gas fraction, comprising a cylindrical shell (1) into which there opens tangentially a conduit (4) for introducing the mixture of gas and solid particles, an axial conduit (2) for removing the gas fraction, means (14), situated in the lower part of the cylindrical shell (1), for removing the particle-enriched fraction, means (10, 11) for introducing a gas used to fluidise the fraction enriched in solid particles into a dense bed (12), and means for heat exchange (13) between the dense fluidised bed formed (12) and a fluid to be vaporised and/or heated, and means (15, 16) allowing the level of the dense bed (12) to be regulated. 
<??>Cyclone for separating off solid particles with preliminary cooling of these particles and improved separation. 
<IMAGE>
Patent DE-69127304-D1 (DE)
Inventor: PEARS DAVID ALAN
IPC: C08F8/00
Filed: 1991-02-06
Granted: 1997-09-25
Abstract: Process for making a polymer with desired groups Y comprising reacting a precursor polymer having carbon- or nitrogen-bound -NH2 and/or -NH- groups with at least one compound having a single enolic carbonyl group and at least one group Y. Also the polymer itself and a composition containing it.
Patent DE-69211958-D1 (DE)
Inventor: RUNNELS DAVID J
IPC: B62M9/08
Filed: 1992-11-02
Granted: 1996-08-08
Abstract: A bicycle is disclosed with a rhomboidal (preferably 60<o> - 120<o>) drive sprocket gear (10) and a circular driven sprocket on the rear driven wheel (26). This gear arrangement varies the overall power input from the drive sprocket (10) to the driven gear (32). The shape of the drive sprocket (10) and the location of the drive pedal (27) changes the gear ratio so that a low gear ratio is utilized during the horizontal portion of movement of the cyclist's legs and a high gear ratio is utilized during the vertical movement of the legs. The gear ratio with the rhomboidal gear (10) is relatively constant during horizontal movement and abruptly changes at the approach to and during vertical movement of the cyclist's legs. While the rhomboidal gear is shown primarily for bicycles it may be used in other systems for converting reciprocal to rotary movement with a change in gear ratio. <IMAGE>
Patent DE-69233247-D1 (DE)
Inventor: FORMAN MICHAEL R
IPC: B29C65/14
Filed: 1992-09-04
Granted: 2003-12-11
Abstract: The present invention provides a process for forming a fluid tight seal between a polymeric body (18) and a polymeric dilatation member (20) surrounding the body comprising positioning the dilatation member along and in surrounding relation to the body with the dilatation member and body aligned to place a first surface portion of the dilatation member and a second surface portion of the body in a contiguous and confronting relation, generating substantially monochromatic energy at a wavelength selected to at least approximately match a wavelength of high spectral absorption of at least one of the polymeric materials forming the dilatation member and body, controllably directing the monochromatic energy onto the body and the dilatation member to concentrate the monochromatic energy in a narrow bond site circumscribing the body and running along the interface of the first and second surface portions, thus to melt the polymeric materials along said bond site and the immediate region thereof and allowing the previously melted polymeric material to cool and solidify to form a fusion bond (36) between the body and dilatation member. <IMAGE>
Patent DE-69309929-D1 (DE)
Inventor: CAVALLETTI ENNIO
IPC: A61K31/435
Filed: 1993-06-14
Granted: 1997-05-22
Abstract: PCT No. PCT/EP93/01494 Sec. 371 Date Dec. 22, 1994 Sec. 102(e) Date Dec. 22, 1994 PCT Filed Jun. 14, 1992 PCT Pub. No. WO94/00141 PCT Pub. Date Jan. 6, 1994The use of glutathione (GSH) as chemoprotective agent against neurotoxicity induced by antitumor drugs active on the mitotic fuse is herein described.
Patent DE-69318282-D1 (DE)
Inventor: BOCZAN JANOS DR MED
IPC: A61N7/00
Filed: 1993-01-22
Granted: 1998-06-04
Abstract: According to the invention, an ultrasound fixture is built into the backrest of the driver's seat of the vehicle, and the ultrasound fixture can be connected to an ultrasound transmitter operated at a low frequency.