baber/WOPTO huggingface dataset:
Patent WO-2019183152-A1 (WO)
Inventor: MENDEZ MICHAEL
IPC: C12N15/82
Filed: 2019-03-19
Abstract: The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.
Patent WO-2019183380-A1 (WO)
Inventor: LI CHIH-PING
IPC: H04B7/06
Filed: 2019-03-21
Abstract: Certain aspects of the present disclosure provide techniques for applying precoding patters to shared channel transmission repetitions. In one example, a method of transmitting data from a device in a wireless communication network, includes: determining a number of repetitions to transmit data in the wireless communication network; determining a precoding pattern that specifies a precoder to be applied to each repetition of the number of repetitions; and transmitting the data according to the number of repetitions and according to the precoding pattern.
Patent WO-2019183403-A1 (WO)
Inventor: BUNT ANTONIUS MARTINUS GUSTAVE
IPC: A61K31/451
Filed: 2019-03-21
Abstract: The present invention relates to efflux inhibitor compounds, compositions, and methods of using the same. More specifically, the instant invention comprises deuterated analogs of elacridar with superior pharmacokinetic properties such that it is now possible to facilitate accumulation and distribution of therapeutic agents to effective levels in cells or compartments protected by efflux transporter proteins such as Breast Cancer Resistance Protein (BCRP) and P-Glycoprotein (P-GP). Such transporter protected compartments include brain, spinal cord, nerves, cerebrospinal fluid, testis, eyeballs, retina, inner ear, placenta, mammary gland, liver, biliary tract, kidney, intestines, lung, adrenal cortex, endometrium, hematopoietic cells, stem cells, and solid tumors. In other embodiments, the present invention comprises methods of using the instant deuterated analogs.
Patent WO-2019195375-A1 (WO)
Title: Integrated circuit packages having electrical and optical connectivity and methods of making the same
Inventor: BRUSBERG LARS MARTIN OTFRIED
IPC: G02B6/42
Filed: 2019-04-03
Abstract: Integrated circuit packages (100) having electrical and optical connectivity and methods of making the same are disclosed herein. According to one embodiment, an integrated circuit package includes a structured glass article (120) including a glass substrate (122), an optical channel (132), and redistribution layers. The integrated circuit package (100) further includes an integrated circuit chip (160) positioned on the glass substrate (122) and in optical communication with the optical channel (132) and in electrical continuity with the redistribution layers (136).
Patent WO-2019200175-A1 (WO)
Title: Regressive suspension spring system
Inventor: CARLSON JASON
IPC: A01B33/02
Filed: 2019-04-11
Abstract: A regressive suspension spring system for a farm implement including a spring arm, a rocker arm, a wheel arm rotatably coupled to the farm implement at a first end and rotatably coupled to the rocker arm at a second end at a first pivot, one or more dogbone links rotatably coupled to the spring arm at a first end of the one or more dogbone links at a second pivot and rotatably coupled to the rocker arm at a second end of the one or more dogbone links at a third pivot; and a spring disposed between the rocker arm and the spring arm. An attachable farm implement including a regressive suspension spring system, such as a rotary cutter. A powered machine including a regressive suspension spring system.
Patent WO-2019217330-A1 (WO)
Title: Method and system for in-line optical scatterometry
Inventor: BRUECK STEVEN
IPC: G01N21/55
Filed: 2019-05-06
Abstract: A system for measuring a periodic array of structures on a sample is provided. The system includes an optical source configured to produce an optical beam; an optical system configured to control the polarization of the optical beam and to focus the optical beam with a first  NA 
   1    on a sample surface and to sweep the angle of incidence across a range of angles with an approximately fixed focal position on a sample surface with a second  NA 
   2    wherein  NA 
   2   
   >  NA 
   1   ; additional optical components configured to receive the optical beam reflected from the sample surface and to focus the reflected beam onto a detector; and a recording system to record the reflectivity of the sample surface as a function of the angle of incidence.
Patent WO-2019222743-A1 (WO)
Title: Boiling point detection and heating system
Inventor: VAN LEEUWEN BRETT
IPC: A47J27/00
Filed: 2019-05-20
Abstract: A method and an apparatus for preparing food. In one example the method comprises the steps of: providing a cooking pan; filing the cooking pan with a food item; wherein the food item is at least partially liquid; placing the pan in thermal connection to a heat source; thermally connecting a temperature sensor to the cooking pan at the temperature sensing location; heating the food in the pan via a heat source having a first thermal output until the food reaches the boiling point; electronically detecting the temperature via the temperature sensor as the food is heated; detecting the temperature as the food item boils, resulting in a phase change and corresponding drop in temperature; and reducing the thermal output of the heat source to a second thermal output.
Patent WO-2019232540-A1 (WO)
Title: Optimization across mobile networks
Inventor: DILLS JAY
IPC: H04W36/00
Filed: 2019-06-03
Abstract: Optimization of network selection across a plurality of mobile networks. In an embodiment, first and second parameters, representing a value of incremental capacity as a function of load, are received for a first network and second network, respectively. In addition, load information is received for both networks. Then, it is determined whether or not to hand over mobile devices from a sector of the first network to a sector of the second network based on the first and second parameters and the load information. When it is determined to perform a hand over, the hand over is triggered by modifying hand-over parameters within the first network.
Patent WO-2019241348-A1 (WO)
Title: Amphiphilic aminoglycoside connexin hemichannel inhibitors
Inventor: ALTENBERG GUILLERMO
IPC: A01N1/02
Filed: 2019-06-12
Abstract: The present invention includes novel molecules and methods of using an amphiphilic kanamycin molecule having substitutions at the O-4", 0-6", or O-4" and 0-6" positions having reduced antimicrobial activity for targeting Connexin Hemichannels.
Patent WO-2020006269-A1 (WO)
Title: Proteasome activity enhancing compounds
Inventor: CULLEN MATTHEW
IPC: C07D401/06
Filed: 2019-06-27
Abstract: The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
Patent WO-2020018251-A1 (WO)
Title: Source code file recommendation notification
Inventor: SWIERC STANISLAW WIKTOR
IPC: G06N7/00
Filed: 2019-06-27
Abstract: A computing device is provided, including a non-volatile storage device and a processor configured to execute a distributed version control system. The processor may, via the distributed version control system, receive a pull request to apply a first set of one or more source code files to a project database. In response to receiving the pull request, the processor may identify a second set of one or more source code files based at least in part on a recommendation ruleset including one or more association rules identified for a plurality of training pull requests applied to a training project database. The recommendation ruleset may be determined based at least in part on a respective last iteration of each training pull request. The processor may output a source code file recommendation notification including an indication of each source code file of the second set.
Patent WO-2020023276-A1 (WO)
Title: Method and apparatus for mission critical standby of a portable communication device
Inventor: SACHS DANIEL GROBE
IPC: H04W52/02
Filed: 2019-07-18
Abstract: A method and apparatus for mission critical standby of a portable communication device are disclosed. A portable communication device may include a primary processor for a first operating platform, a secondary processor for a second operating platform and communicatively coupled to the primary processor, and a power state manager that may have a first mode and a second mode. The power state manager may be configured to determine whether the primary processor is in a powered off state and sequence supply of power to the secondary processor. The first mode may allow the primary processor to monitor a power state of the secondary processor based on a determination that the primary processor is not in the powered off state and the second mode may enable the power state manager to monitor the power state based on a determination that the primary processor is in the powered off state.
Patent WO-2020047186-A1 (WO)
Inventor: O'MALLEY BERT W
IPC: A61P9/10
Filed: 2019-08-29
Abstract: Small molecule stimulators of steroid receptor coactivator-3 (SRC-3) and methods of their use as cardioprotective agents are provided. The small molecule stimulators are useful for promoting cardiac protection and repair and vascular regeneration after myocardial infarction. The compounds are also useful in preventing cardiac hypertrophy and collagen deposition and improving cardiac post-infarction function.
Patent WO-2020051200-A1 (WO)
Title: Apparatus and methods for removal of subcutaneous fat using dissolution agent
Inventor: ASADOV VADIM
IPC: A61B34/30
Filed: 2019-09-04
Abstract: A method includes coupling a needle cartridge to a treatment head of a robotic lipolysis treatment device. The cartridge includes a needle array having multiple needles. The treatment head can be positioned at a designated treatment area on a patient with a bottom end in contact with the patient's skin. The treatment head can be actuated to insert at least a portion of the needles through the skin of the patient and into the underlying subcutaneous fat layer of the patient. A dissolution agent can be injected through the needles and into the subcutaneous fat layer. The cartridge can include a top portion having the multiple needles and a bottom portion removably coupleable to the top portion. The dissolution agent can be disposed in a chamber in the bottom portion and can be drawn into the needles or the needles can be prefilled with a dose of dissolution agent.
Patent WO-2021050060-A1 (WO)
Title: Adaptive guard period for beam switching for wireless networks
Inventor: PAJUKOSKI KARI PEKKA
IPC: H04B7/06
Filed: 2019-09-11
Abstract: According to an example embodiment, a method may include determining, by a base station, a beam switching time for the base station; determining, by the base station, a predetermined fraction of a cyclic prefix length of a cyclic prefix to be used by the base station for transmission of one or more symbols; determining that the beam switching time for the base station exceeds the predetermined fraction of the cyclic prefix length; and adding a guard period to at least one of a last symbol, of a first set of one or more symbols, associated with a first beam and/or a first symbol, of a second set of one or more symbols, associated with a second beam, wherein the first symbol associated with the second beam is transmitted after and adjacent to the last symbol associated with the first beam.
Patent WO-2020068612-A1 (WO)
Title: Detecting ransomware
Inventor: MEHTA KUNAL
IPC: G06F21/56
Filed: 2019-09-23
Abstract: There is disclosed in one example a ransomware mitigation engine, including: a processor; a convolutional neural network configured to provide file type identification (FTI) services including: identifying an access operation of a file as a write to the file or newly creating the file; computing a byte correlation factor for the file; classifying the file as belonging to a file type; determining with a screening confidence that the file type is correct for the file; determining that the screening confidence is below a screening confidence threshold; and circuitry and logic to provide heuristic analysis including: receiving notification that the confidence is below the confidence threshold; performing a statistical analysis of the file to determine a difference between an expected value and a computed value; determining from the difference, with a detection confidence, that the file has been compromised; and identifying the file as having been compromised by a ransomware attack.
Patent WO-2020096707-A1 (WO)
Inventor: LEE SUNHYUNG
IPC: G03G7/00
Filed: 2019-09-26
Abstract: A fixing device includes a pressing member including a nip plate, and an electron beam-irradiated fluorinated resin film is to be on an outer surface of the nip plate facing toward the backup member.
Patent WO-2020072397-A1 (WO)
Title: Block size based motion vector coding in affine mode
Inventor: GALPIN Franck
IPC: H04N19/537
Filed: 2019-10-01
Abstract: At least a method and an apparatus are presented for efficiently encoding or decoding video. For example, a plurality of motion vectors are obtained for used in determining motion information for a block using affine modeling, wherein at least one of the plurality of motion vectors is determined based on a block size of the block. The video is then encoded or decoded based on the plurality of motion vectors.
Patent WO-2020077206-A1 (WO)
Inventor: HLA TIMOTHY
IPC: C07K14/775
Filed: 2019-10-11
Abstract: Provided herein are methods of treating lung disease using fusion proteins comprising ApoM (e.g., human or murine ApoM) fused to a constant region (Fc) of a immunoglobulin G (IgG, e.g., human IgG or murine IgG).
Patent WO-2020086643-A1 (WO)
Inventor: PETERSEN CHRISTOPHER
IPC: B26B21/52
Filed: 2019-10-23
Abstract: A fingertip shaver has a generally cylindrical shape and requires no extension or moving parts. The blade or multiple blades of the shaver are provided in a cartridge mounted within in an opening or recess formed in a flattened or truncated portion of the cylinder.
Patent WO-2020086799-A1 (WO)
Title: Biostimulator feedthrough having integrated electrode cup
Inventor: PASPA PAUL
IPC: A61N1/05
Filed: 2019-10-24
Abstract: A biostimulator, such as a leadless cardiac pacemaker, including an electrical feedthrough assembly mounted on a housing, is described. An electronics compartment of the housing can contain an electronics assembly to generate a pacing impulse, and the electrical feedthrough assembly can include an electrode tip to deliver the pacing impulse to a target tissue. A monolithically formed electrode body can have a pin integrated with a cup. The pin can be electrically connected to the electronics assembly, and the cup can be electrically connected to the electrode tip. Accordingly, the biostimulator can transmit the pacing impulse through the monolithic pin and cup to the target tissue. The cup can hold a filler having a therapeutic agent for delivery to the target tissue and may include retention elements for maintaining the filler at a predetermined location within the cup. The retention elements may comprise a coil, spring, or spacer that bias the filler toward a base of the cup and away from the electrode tip.
Patent WO-2020096885-A1 (WO)
Title: Magnetic housing systems
Inventor: GANDIKOTA SRINIVAS
IPC: C23C16/505
Filed: 2019-11-01
Abstract: Embodiments described herein relate to magnetic and electromagnetic systems and a method for controlling the density profile of plasma generated in a process volume of a PECVD chamber to affect deposition profile of a film. In one embodiment, a plurality of retaining brackets is disposed in a rotational magnetic housing of the magnetic housing systems. Each retaining bracket of the plurality of retaining brackets is disposed in the rotational magnetic housing with a distance d between each retaining bracket. The plurality of retaining brackets has a plurality of magnets removably disposed therein. The plurality of magnets is configured to travel in a circular path when the rotational magnetic housing is rotated around the round central opening.
Patent WO-2020097618-A1 (WO)
Title: Deep brain stimulation using artificial neural networks
Inventor: ZYLBERBERG JOEL
IPC: A61N1/00
Filed: 2019-11-12
Abstract: Various embodiments of the present technology generally relate to closed loop deep brain stimulation based on inferred sleep stage from physiological data using machine learning classifiers. Some embodiments, for example, may use subthalamic nucleus (STN) deep brain stimulation (DBS) to treat advanced Parkinsons Disease motor symptoms and improve sleep by identifying sleep stages commensurate with clinician-scored polysomnography (PSG). The DBS may be adapted to include novel artificial neural network (ANN) that triggers targeted stimulation in response to inferred sleep state from STN local field potentials (LFPs) recorded from implanted DBS electrodes. A feedforward neural network can be trained to prospectively identify sleep stage with PSG-level accuracy. In some embodiments, the machine learning model stored within the DBS may also adapt stimulation during specific sleep stages to treat targeted sleep deficits.
Patent WO-2020106506-A1 (WO)
Inventor: THIAGARAJAN PRABU RAJ
IPC: H04L45/122
Filed: 2019-11-13
Abstract: A method for load balancing among multiple endpoint computing systems of a domain includes receiving a request to access the domain; identifying a target endpoint from the multiple endpoint computing systems based on routing logic for the domain; obtaining a load metric for the target endpoint; determining whether the load metric for the target endpoint satisfies an overload condition; and redirecting a fractional portion of traffic of the domain away from the target endpoint and to an alternate endpoint of the multiple endpoint computing systems in response to determining that the load metric for the target endpoint satisfies the overload condition.
Patent WO-2020106687-A1 (WO)
Title: Ribbon bond solution for reducing thermal stress on an intermittently operable chipset controlling rf application for cooking
Inventor: CARCANO MARCO
IPC: H05B6/68
Filed: 2019-11-19
Abstract: Power amplifier electronics for controlling application of radio frequency (RF) energy generated using solid state electronic components may further be configured to control application of RF energy in cycles between high and low powers. The power amplifier electronics may include a semiconductor die on which one or more RF power transistors are fabricated, an output matching network configured to provide impedance matching between the semiconductor die and external components operably coupled to an output tab, and bonding ribbon bonded at terminal ends thereof to operably couple the one or more RF power transistors of the semiconductor die to the output matching network. The bonding ribbon may have a width of greater than about five times a thickness of the bonding ribbon.
Patent WO-2020106699-A1 (WO)
Title: Sensing of a water level in refrigerated cabinets
Inventor: GUPTA ANKIT ANAND
IPC: G01F23/296
Filed: 2019-11-19
Abstract: A system for monitoring a water collecting container includes a first sensor operable to detect if water is present within the water collecting container, a second sensor operable to determine a level of water within the water collecting container, and a processing device operably coupled to the first sensor and the second sensor.
Patent WO-2020163002-A1 (WO)
Inventor: SCHMOGROW RENE
IPC: H04L45/122
Filed: 2019-11-22
Abstract: L'invention concerne des systèmes et des procédés d'attribution de circuits optiques sur des réseaux maillés optiques. Par exemple, les procédés décrits comprennent l'identification d'un nouveau circuit à ajouter à un réseau optique maillé et l'identification d'un ensemble de trajets potentiels pour le nouveau circuit. Pour chaque liaison optique dans chaque trajet de potentiel identifié, des coûts sont déterminés pour une pluralité d'intervalles de fréquence d'attribution du nouveau circuit à un trajet potentiel comprenant la liaison optique. Le coût d'attribution d'une tranche de fréquence donnée sur une liaison optique donnée est déterminé en partie sur la base des longueurs de circuits optiques qui peuvent traverser la liaison optique donnée à l'aide de cette intervalle de fréquence. Des valeurs de coût total sont calculées pour attribuer des intervalles de fréquence disponibles sur chacun des trajets potentiels identifiés, et l'un des trajets potentiels identifiés et une ou plusieurs des intervalles de fréquence disponibles sont attribués pour le nouveau circuit.
Patent WO-2020112745-A1 (WO)
Title: Fenêtre multilatérale et déflecteur combinés et système de jonction
Inventor: HEPBURN NEIL
IPC: E21B29/06
Filed: 2019-11-26
Abstract: Selon un aspect, l'invention concerne un ensemble déflecteur à fenêtre. L'ensemble déflecteur à fenêtre selon l'aspect de l'invention comprend un logement tubulaire, le logement tubulaire ayant une fenêtre à travers celui-ci, une enveloppe recouvrant la fenêtre et un déflecteur couplé au logement tubulaire ou formé d'un seul tenant en tant que partie de celui-ci.
Patent WO-2020118164-A1 (WO)
Title: Eyewear with multi-axis side arms
Inventor: SHANELARIS PETER
IPC: F16C11/06
Filed: 2019-12-06
Abstract: A joint for coupling a side arm to a frame of a pair of glasses. The joint includes a post, a plurality of prongs, and optionally a nut. The post is configured to be secured to one of the side arm or the frame and the plurality of prongs are configured to be secured to the other of the side arm or the frame. The post includes a shaft and an enlarged head at a distal end of the shaft. The plurality of prongs define a socket configured to receive at least a portion of the enlarged head of the post and apply a compressive force against the enlarged head of the post. The nut may be configured to generate a compressive force against the plurality of prongs. The compressive force may be adjusted by threading the nut along the length of the prongs. The nut may threadably engage a base that the prongs extend from and/or the prongs.
Patent WO-2020118192-A1 (WO)
Title: Engineered flagellin-derived compositions and uses
Inventor: METT VADIM
IPC: A61K39/02
Filed: 2019-12-06
Abstract: The present invention provides improved pharmacologically optimized and deimmunized flagellin variants and methods of use that exhibit reduced immunogenicity and reduced inflammasome response while still retaining the ability to activate TLR5 signaling.
Patent WO-2020132179-A1 (WO)
Title: Multilayer filter including a capacitor connected with at least two vias
Inventor: CHOI KWANG
IPC: H03H7/01
Filed: 2019-12-19
Abstract: A multilayer filter may include a plurality of dielectric layers stacked in a Z-direction. A first conductive layer may overlie one of the dielectric layers, and a second conductive layer may overlie another of the dielectric layers and be spaced apart from the first conductive layer in the Z-direction. A first via may be connected with the second conductive layer at a first location. A second via may be connected with the second conductive layer at a second location that is spaced apart in a first direction from the first location. The first conductive layer may overlap the second conductive layer at an overlapping area to form a capacitor. At least a portion of the overlapping area may be located between the first location and the second location in the first direction. The second conductive layer may be free of via connections that intersect the overlapping area.