baber/WOPTO huggingface dataset:
Patent DE-69520947-D1 (DE)
Inventor: PAL BIMAN
IPC: C07C273/18
Filed: 1995-07-05
Granted: 2001-06-21
Abstract: The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. The method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3-substituted-2-propanol chemical intermediate.
Patent DE-69522586-D1 (DE)
Inventor: SLOCUM H
IPC: H01L21/66
Filed: 1995-10-11
Granted: 2001-10-11
Abstract: A manipulator for a test head connected to automatic test equipment through a heavy, inflexible cable. The manipulator includes a telescoping column assembly to which is mounted a vertical member. A cradle holding the test head is mounted to the vertical member. The cable is clamped at the vertical member to reduce the amount of force exerted by the cable on the test head. The cradle includes movable members to allow fine positioning of the test head, while maintaining the test head isolated from cable force. Course motion of the test head may be made by moving portions of the manipulator on the opposite side of the cable clamp from the test head. Precise positioning of the test head relative to a handling device is accomplished through a positioning mechanism at the interface between the test head and the handling device. To allow the positioning mechanism to operate, the manipulator has compliance which allows the test head to be forced into position by the positioning mechanism.
Patent DE-69526450-D1 (DE)
Inventor: LYONS T
IPC: A61K9/107
Filed: 1995-12-01
Granted: 2002-05-23
Abstract: An acidic emulsion comprising a lipoid dispersed in an aqueous phase, a cationic sphingolipid, and a stabilizing amount of non-ionic surfactant and cholesterol is provided, along with the method of administering the emulsion.
Patent DE-69534608-D1 (DE)
Inventor: ISRAEL HENRY M
IPC: A61M5/00
Filed: 1995-07-26
Granted: 2005-12-15
Abstract: The stent (30) is formed of a tube having a patterned shape which has first and second meander patterns having axes extending in first and second directions. The first meander patterns can be formed in even and odd first meander patterns. The even and odd first meander patterns are 180 deg. out of phase with each other, and the odd patterns occur between every two even patterns. The second meander patterns are intertwined with the first meander patterns. The first and second directions can be orthogonal to each other. The second meander patterns can also be formed of even and odd patterns.
Patent DE-69607591-D1 (DE)
Inventor: BRENDENG EINAR
IPC: B01D8/00
Filed: 1996-01-11
Granted: 2000-05-11
Abstract: PCT No. PCT/NO96/00005 Sec. 371 Date Jul. 28, 1997 Sec. 102(e) Date Jul. 28, 1997 PCT Filed Jan. 11, 1996 PCT Pub. No. WO96/22221 PCT Pub. Date Jul. 25, 1996A method for condensation of gaseous hydrocarbons from a mixture of inert gas and gaseous hydrocarbons, particularly as found in storage tanks of an LPG/LEG ship. According to the method, the condensate and the cargo gas composition are heat exchanged with a part of its condensate, and with a cargo gas/inert gas mixture, which is to be released to the atmosphere or burned, in a separate condensation step.
Patent DE-69608711-D1 (DE)
Inventor: LUKER KEITH
IPC: B29C48/455
Filed: 1996-01-19
Granted: 2000-07-13
Abstract: An apparatus is provided for extruding a polymer which is subject to periodic surges. The apparatus includes a barrel with an upstream portion for receiving polymer, a downstream portion and a discharge port (D) near the downstream portion. The apparatus also includes a shaft (S) mounted for rotational movement about a longitudinal axis within the barrel as well as drive (DR) means connected to rotate the shaft. The apparatus has a surge suppressor (SS) for urging polymer upstream toward the discharge port (D) while permitting a portion of polymer to flow downstream into the surge suppressor (SS). A sensor (PS) is positioned within the apparatus to detect surges in the polymer and a controller is connected to the sensor and to the drive means for adjusting shaft rotation in response to polymer surges. <IMAGE>
Patent DE-69616523-D1 (DE)
Inventor: HOPE MICHAEL
IPC: A61K9/127
Filed: 1996-02-27
Granted: 2001-12-06
Abstract: Methods for the preparation of stable liposome formulations of protonatable therapeutic agents. The methods involve loading a therapeutic agent into preformed liposomes having a methylamine concentration gradient across the lipid bilayer of the liposomes. These methods provide liposome formulations which are more stable, more cost effective, and easier to prepare in a clinical environment than those previously available. The present invention also provides the pharmaceutical compositions prepared by the above methods, a kit for the preparation of liposome formulations of therapeutic agents, and methods for their use.
Patent DE-69622116-D1 (DE)
Inventor: PELTOMAEKI TERO
IPC: B65G1/04
Filed: 1996-10-01
Granted: 2002-08-08
Abstract: A robot system comprising a robot (12) movable over a working area in which a plurality of goods units is arranged in vertical stacks. The robot has a vertically movable gripping device (20) for enabling at least one goods unit to be picked from or unloaded onto a stack. The gripping device (20) has a load space which is dimensioned to carry a plurality of goods units stacked one on top of each other. A method of using the robot system is also disclosed. <IMAGE>
Patent DE-69625339-D1 (DE)
Inventor: KUSLICH STEPHEN D
IPC: A61B17/70
Filed: 1996-02-27
Granted: 2003-01-23
Abstract: An spinal fixation device for stabilizing vertebrae. A hollow screw is inserted into a hole saw recess in each adjoining vertebrae. A channel is cut into the vertebrae into which a joining rod is inserted such that no part of the device protrudes above the bone. A locking cap is used to secure the rod to the screws.
Patent DE-69626770-D1 (DE)
Inventor: FRANCESCUTTO GIANNI
IPC: B60L50/15
Filed: 1996-12-18
Granted: 2003-04-24
Abstract: The system includes a generator unit (1) comprising a heat engine which powers the generator which supplies a current (Io) at continuous voltage (Uo) to a two wire supply system (2). The generator unit (1) is controlled by a regulating unit (8) which receives a signal (Sc) from an accelerator (6) and an engine speed signal (Sng). The propulsion unit (3) contains an electric motor which drives a road wheel (4) through a shaft (5) and it is controlled by a regulation unit (9). The regulation unit receives a supply voltage signal (SUo) and compares it to a preset value (SUoc). A correcting signal (Sp) is then sent to the propulsion unit (3).
Patent DE-69627703-D1 (DE)
Inventor: MEADE J
IPC: C12Q1/68
Filed: 1996-06-07
Granted: 2003-05-28
Abstract: The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes.
Patent DE-69630524-D1 (DE)
Inventor: COWGILL CYNTHIA
IPC: C12R1/84
Filed: 1996-06-07
Granted: 2003-12-11
Abstract: Methods for purifying authentic, properly folded IGF polypeptides from yeast transformants are disclosed. The methods include a refolding step and provide for high yields of authentic IGF from a variety of yeast strains.
Patent DE-69633392-D1 (DE)
Inventor: FERGUSON WILLIAM
IPC: C08B37/00
Filed: 1996-07-31
Granted: 2004-10-21
Abstract: PCT No. PCT/GB96/01841 Sec. 371 Date May 14, 1998 Sec. 102(e) Date May 14, 1998 PCT Filed Jul. 31, 1996 PCT Pub. No. WO97/05892 PCT Pub. Date Feb. 20, 1997The present invention concerns soluble betaglycan for use in promoting the healing of wounds or fibrotic disorders with reduced scarring, together with methods for same.
Patent DE-69633630-D1 (DE)
Inventor: SLABAS RYSZARD
IPC: A01H5/00
Filed: 1996-08-06
Granted: 2004-11-18
Abstract: PCT No. PCT/GB96/01894 Sec. 371 Date Jan. 20, 1998 Sec. 102(e) Date Jan. 20, 1998 PCT Filed Aug. 6, 1996 PCT Pub. No. WO97/07222 PCT Pub. Date Feb. 27, 1997The capacity of a plant to produce fatty acids is modulated by controlling the expression of a gene specifying the acetyl CoA carboxylase biotin carboxyl carrier protein. Modulation may comprise increasing the expression of the gene by insertion of additional copies into the genome or inhibiting expression by insertion of an antisense or cosuppression vector directed against the endogenous gene.
Patent DE-69636546-D1 (DE)
Inventor: CHOULIKA ANDRE
IPC: C12N15/09
Filed: 1996-07-25
Granted: 2006-10-26
Abstract: A natural or synthetic retroelement sequence (I), pref. retroviral DNA, comprises an insertion sequence (IS) incorporated into a region that can be transferred to a target cell and integrated into a recombinant provirus during infection of the cell by a retrovirus contg. (I). IS contains a sequence of interest (II), able to integrate into the cell genome, and a recognition sequence (III), pref. a single (III) that can be recognised by a recombinase.
Patent DE-69636579-D1 (DE)
Inventor: KIRLIN S
IPC: G02B6/036
Filed: 1996-06-06
Granted: 2006-11-09
Abstract: A metalorganic complex of the formula:MAyXwherein: M is a y-valent metal; A is a monodentate or multidentate organic ligand coordinated to M which allows complexing of MAy with X; y is an integer having a value of 2, 3 or 4; each of the A ligands may be the same or different; and X is a monodentate or multidentate ligand coordinated to M and containing one or more atoms independently selected from the group consisting of atoms of the elements C, N, H, S, O and F. The metal M may be selected from the group consisting of Cu, Ba, Sr, La, Nd, Ce, Pr, Sm, Eu, Th, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Bi, Tl, Y, Pb, Ni, Pd, Pt, Al, Ga, In, Ag, Au, Co, Rh, Ir, Fe, Ru, Sn, Li, Na, K, Rb, Cs, Ca, Mg, Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, and W. A may be selected from the group consisting of  beta -diketonates and their sulfur and nitrogen analogs,  beta -ketoesters and their sulfur and nitrogen analogs, cyclopentadienyls, alkyls, perfluoroalkyls, alkoxides, perfluoroalkoxides, and Schiff bases. X may for example comprise a ligand such as tetraglyme, tetrahydrofuran, bipyridine, crown ether, or thioether.
Patent DE-69705740-D1 (DE)
Inventor: ANDRE JEAN-LUC
IPC: B60P7/08
Filed: 1997-12-09
Granted: 2001-08-23
Abstract: The flexible link is a securing strap (2) which rests on the tire (5) and is tightened with respect to two fixed points on a carrying structure (7) by which the ends of the strap are retained with fixing pieces. The surface in contact with the running tread comprises successive groups (25) of a plurality of transversal support elements (26) in the form of rollers with a central rod and widened ringed tips (28) and (29) forming contiguous rail wheels by which the strap rests on the tire. This invention is applicable in the field of transport when the load consists of road vehicles.
Patent DE-69706070-D1 (DE)
Inventor: MURAOKA TAKATERU
IPC: A61K47/14
Filed: 1997-05-26
Granted: 2001-09-13
Abstract: The present invention relates to a percutaneous preparation comprising an adhesive layer formed on at least one side of a substrate, the layer containing an acrylic copolymer, 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole or an acid addition salt thereof, and 2-mercaptobenzimidazole. This preparation exhibits superior percutaneous absorption of the benzimidazole compound and long sustention of efficacy, and shows an improved stability of the active ingredient, benzimidazole compound, in the preparation.
Patent DE-69713302-D1 (DE)
Inventor: FOGED CHRISTIAN
IPC: C07D487/04
Filed: 1997-03-18
Granted: 2002-07-18
Abstract: PCT No. PCT/FI97/00177 Sec. 371 Date Sep. 11, 1998 Sec. 102(e) Date Sep. 11, 1998 PCT Filed Mar. 18, 1997 PCT Pub. No. WO97/34898 PCT Pub. Date Sep. 25, 1997A process for producing a carrier free radio halogenated 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine of formula (II) where R1 is a radioactive halogen and R1 may be at 7, 8, 9 or 10 substituent. The above compound is used in a pharmaceutical composition for nuclear medicine examination.
Patent DE-69724601-D1 (DE)
Inventor: GALLETTI PAOLO
IPC: G01G11/00
Filed: 1997-12-23
Granted: 2003-10-09
Abstract: This invention concerns a device which automatically separates and weighs out the metal fibres, loaded into the device as tangled bundle, that are then mixed with cement mixtures; it being provided that the device - thanks to a selector roller - separates the single fibres of the tangled bundle and weighs out the correct measure by means of loading cells co-operating with a control and command unit. <IMAGE>
Patent DE-69725438-D1 (DE)
Inventor: CARCIA FRANCIS
IPC: G03F1/32
Filed: 1997-05-09
Granted: 2003-11-13
Abstract: Attenuating embedded phase shift photomask blanks capable of producing a 180 DEG  phase shift with an optical transmissivity of at least 0.0001 at wavelengths <400 nm comprise alternating layers, either periodic or aperiodic, of an optically transmissive material and an optically absorbing material and are made by depositing alternating layers of optically transmissive material and optically absorbing material on a substrate, preferably by vapor deopsition.
Patent DE-69735345-D1 (DE)
Inventor: CHIARONI DOMINIQUE
IPC: H04B10/29
Filed: 1997-06-09
Granted: 2006-04-27
Abstract: The processor receives an input signal (E) at a first stage (1) and outputs a modulated signal which has a power value between first and second power levels. Power level fluctuations due to variations in the input signal are reduced. The smoothed modulated output (B) is passed to a second stage (2) with an interferometer (7) which splits the incoming signal into auxiliary waves (AM1,AM2) and produces a signal that accentuates the input modulation by generating constructive and destructive interference outputs. The two logic output states are thus more clearly defined.
Patent DE-69738112-D1 (DE)
Inventor: GERRITY DAN
IPC: B07B1/24
Filed: 1997-02-28
Granted: 2007-10-18
Abstract: A coin conditioner is provided for cleaning or otherwise conditioning coins in a coin discriminator apparatus prior to transfer to a coin sensor. Coins enter through a feed tray and move down the length of a perforated tumbler, preferably without the use of gravity, such as under screw force, mechanical or centrifugal force. The spinning tumbler is preferably rotated about its longitudinal axis by a motor. In one embodiment, a blower or vacuum draws or moves air from one area to another, with the air preferably being filtered. As coins move through and down a tumbler, projections such as vanes, fins, ridges, dimples, spines or other raised features cause mechanical agitation and/or abrasion as coins are lifted and dropped while passing longitudinally through the tumbler. The coins are conditioned and non-coin matter is collected as it is separated and/or abraded from the coin surfaces. Tumbler perforations permit non-coin matter to pass through the perforations into a collection tray or other apparatus and/or are collected into filter media as a result of the air flow. In one embodiment, the air pressure system eliminates or reduces the occurrence of low density or light non-coin matter, such as hair or dust, and prevents these materials from settling or being carried through downstream portions of the coin processing system.
Patent DE-69739473-D1 (DE)
Inventor: BERGERON MICHEL G
IPC: C07K14/245
Filed: 1997-11-04
Granted: 2009-08-06
Abstract: DNA-based methods employing amplification primers or probes for detecting, identifying, and quantifying in a test sample DNA from (i) any bacterium, (ii) the species  Streptococcus agalactiae, Staphylococcus saprophyticus, Enterococcus faecium, Neisseria meningitidis, Listeria monocytogenes  and  Candida albicans,  and (iii) any species of the genera  Streptococcus, Staphylococcus, Enterococcus,  Neisseria and  Candida  are disclosed. DNA-based methods employing amplification primers or probes for detecting, identifying, and quantifying in a test sample antibiotic resistance genes selected from the group consisting of  bla tem , bla rob , bla shv , bla oxa , blaZ,  aadB,  aacC1,  aacC2, aacC3,  aacA4,  aac6'-IIa,  ermA, ermB, ermC, mecA, vanA, vanB, vanC, satA, aac(6)-aph(2"),  aad(6'),  vat, vga, msrA, sul  and  int  are also disclosed. The above microbial species, genera and resistance genes arc all clinically relevant and commonly encountered in a variety of clinical specimens. These DNA-based assays are rapid, accurate and can be used in clinical microbiology laboratories for routine diagnosis. These novel diagnostic tools should be useful to improve the speed and accuracy of diagnosis of microbial infections, thereby allowing more effective treatments. Diagnostic kits for (i) the universal detection and quantification of bacteria, and/or (ii) the detection, identification and quantification of the above-mentioned bacterial and fungal species and/or genera, and/or (iii) the detection, identification and quantification of the above-mentioned antibiotic resistance genes arc also claimed.
Patent DE-69802286-D1 (DE)
Inventor: VEYRAT DIDIER
IPC: C08J7/048
Filed: 1998-07-14
Granted: 2001-12-06
Abstract: The invention concerns composite metallized polyester films with good barrier properties relative to gases. More precisely, it concerns a biaxially drawn composite metallized film based on polyester and having improved barrier properties to gases, characterized in that the composite comprises a polyester film base of 5 mum to 50 mum, directly coated on one of its two faces with a layer including a mixture of a polyvinyl alcohol which has an average degree of polymerization in number equal to or in excess of 350 and a water-dispersible copolyester with sulphonyloxy residues, the layer including the polyvinyl alcohol and the water-dispersible copolyester being in turn coated with a metal layer, the composite film exhibiting a permeability to oxygen, measured at 23° C. under 50% relative humidity, equal to or lesser than 0.4 cm3/m2/24 h. The composite metallized polyester films have, besides their barrier properties, excellent resistance to mechanical stresses, such as in particular crumpling.
Patent DE-69810282-D1 (DE)
Inventor: HUYNH LE
IPC: A61F2/24
Filed: 1998-03-25
Granted: 2003-01-30
Abstract: Prosthetic heart valve suture rings having a suturable annulus of a compliant internal member and a cloth covering. Three evenly spaced upwardly opening depressions formed on an internal circumference of the suturable annulus receive downwardly-directed cusps of a stent structure of the heart valve. The suture ring may include a silicone sponge waffle annulus having a walled lip on an inner circumference thereof. The lip is contoured to include the three depressions, and a ring washer mounts on the annulus surrounding the walled lip for added stiffness.
Patent DE-69815831-D1 (DE)
Inventor: VALENTINO JOSEPH A
IPC: B60R1/02
Filed: 1998-02-27
Granted: 2003-07-31
Abstract: An automatic mirror rotation assembly for a vehicle including a tractor and semi-detached trailer is provided. A control wheel is mounted in a structure connecting to a chassis of the tractor, and is raised into engagement with a lower surface of the trailer. As the vehicle turns, the rotation of the trailer with respect to the tractor is measured by counting rotations or partial rotations of the wheel against the underside surface of the trailer. A corresponding degree of passenger-side rear view mirror is calculated, and a motor automatically rotates the mirror.
Patent DE-69816448-D1 (DE)
Inventor: HAMMERICH CHRISTIAN
IPC: F16K31/06
Filed: 1998-05-07
Granted: 2003-08-21
Abstract: A solenoid valve comprising a coil surrounding a guide for an armature, the armature being movable in the guide through magnetising of the coil or by means of a return mechanism, and a valve seat co-operating with a closing member for selective opening or closing of a valve opening through the valve seat controlled by the armature movement. As the closing member is a separate device in relation to the armature, which closing member is activated by the armature movement to a rocking movement around a contact point with the valve seat, an normally open or normally closed solenoid is obtained.
Patent DE-69835299-D1 (DE)
Inventor: VAN GEMEN BOB
IPC: C12Q1/6865
Filed: 1998-11-11
Granted: 2006-08-31
Abstract: The present invention is directed to a transcription based amplification method for the amplification of DNA targets. With the method of the present invention an isothermal transcription based amplification method is provided for the amplification of double stranded DNA. The method of the present invention for the amplification of double stranded DNA comprises the steps of contacting said double stranded DNA with at least one oligonucleotide comprising a sequence complementary to a part of the first of the two DNA strands comprised in the double stranded DNA, said oligonucleotide further comprising the sequence of a promoter recognized by a RNA polymerase; a further olignucleotide comprising a sequence complementary to a part of the second strand comprised in the double stranded DNA; an enzyme having RNA dependent DNA polymerase activity; an enzyme having DNA dependent DNA polymerase activity; an enzyme having RNase H activity; an enzyme having RNA polymerase activity, and maintaining the thus created reaction mixture under the appropriate conditions for a sufficient amount of time for the amplification to take place. The method according to the invention is particularly useful for amplifying small DNA molecules, e.g. plasmid DNA. Surprisingly, transcription based amplification can start from double stranded DNA, without the need to treat the DNA with restriction enzymes or, what is more important, to separate the strands before hand by applying heat. All reagents conventionally used with isothermal transcription based amplification reactions can simply be used on starting material containing double stranded DNA, as if it where single stranded RNA. With the present invention it has now been found that essentially the same protocols can be used for isothermal transcription based amplification of double stranded DNA. The method is particularly useful for the detection of small DNA molecules of pathogenic microorganisms enabling diagnosis. In particular the circular HIV-1 DNA molecules that are formed during the replication of the HIV-1 virus can be detected by this method. Detection of such circular HIV-1 DNA molecules indicates active replication of the virus, which can be correlated with disease progression, i.e. development of AIDS.