baber/WOPTO huggingface dataset:
Patent CA-2497313-A1 (CA)
Title: Biomolecule transfer method using virus envelope and composition and system therefor
Inventor: MORISHITA RYUICHI
IPC: A61K39/00
Filed: 2003-08-22
Abstract: It is intended to provide an efficient transduction method to the brain/central nerve system and a more efficient transduction method with the use of a virus envelope. Namely, a system for transferring a biomolecule into cells which contains: A) the biomolecule; B) a virus envelope; and C) glycosaminoglycan; and a method of transducing a biomolecule into the brain which involves the following steps: A) the step of transiently closing the cephalic or cervical artery; and B) the step of transferring the biomolecule into the brain while closing the cephalic or cervical artery.
Patent CA-2498096-A1 (CA)
Inventor: BENECKE ARNOLD G
IPC: A47L13/256
Filed: 2000-09-26
Abstract: A cleaning implement is provided. The cleaning implement includes a liquid delivery system for providing a cleaning liquid to a surface to be cleaned having a canister for storing a liquid, an electrical motor driving a pump, and a voltage source for energizing the electric motor. A support tread is pivotally attached to the handle for releasably receiving a cleaning sheet. The handle includes a switch and is formed from a plurality of handle sections. Each handle section has at least one electrical connector which is electrically connected with an electrical connector of an adjacent handle section so that the switch can activate the electrical motor. The support head can be configured to allow visual inspection of the cleaning sheet through the support head during use. The canister is provided with a plurality of side walls and vent valve having a cracking pressure of at least about 0.6 Kpa, wherein the canister is substantially in the form of a parallelogram in a plan view cross section and wherein one or more of the side walls has a plurality of grooves.
Patent CA-2504645-A1 (CA)
Title: Warehouse for providing transfer cars
Inventor: WIEDEMANN GEORG
IPC: G07F17/10
Filed: 2003-11-19
Abstract: The invention relates to a warehouse (1) for providing transfer cars (6) whi ch are guided in at least one guiding rail (2) in a successively arranged manne r. The inventive warehouse comprises at least one unlockable transit barrier (3 ) for retaining or releasing the transfer cars (6), and a money cashing device (5) which is used to trigger the transfer cars (6) and is electrically connected to the at least one transit barrier (3). The invention is characterised in that the at least one transit barrier (3) is either exclusively carried by the at least one guiding rail (2) or is at least partially supported on the floor.
Patent CA-2505913-A1 (CA)
Inventor: UBER ROBERT E
IPC: G01N21/17
Filed: 2004-05-12
Abstract: The present invention relates to a photoacoustic gas sensor utilizing diffusion having a sensing volume and an acoustic pressure sensor volume containing an acoustic pressure sensor such that the fluid connection between the sensing volume and the acoustic pressure sensor volume restricts the flow of analyte gas therethrough but does not restrict the transmission of the photoacoustic signal therethrough.
Patent CA-2506460-A1 (CA)
Inventor: DUBAY JERAMY M
IPC: G01L5/16
Filed: 2005-05-06
Abstract: A multi-axis force analyzer and data acquisition system is disclosed. Using non-invasive structure, parts to be tested are analyzed without obstructing user access or defacing the object in any way. Accordingly, the forces required to open and close a container can be accurately and easily measured.
Patent CA-2507698-A1 (CA)
Title: Arrangement and method for production of a three dimensional object
Inventor: LARSSON MORGAN
IPC: B22F10/366
Filed: 2003-12-12
Abstract: Arrangement for producing a three-dimensional product, which arrangement comprises a work table on which said three-dimensional product is to be built up, a powder dispenser which is arranged so as to distribute a thin layer of powder on the work table for forming a powder bed, a radiation gun for delivering energy to the powder, fusing together of the powder then taking place, means for guiding the beam emitted by the radiation gun over said powder bed for forming a cross section of said three-dimensional product by fusing together parts of said powder bed, and a control computer in which information about successive cross sections of the three-dimensional product is stored, which cross sections build up the three-dimensional product, where the control computer is intended to control said means for guiding the radiation gun over the powder bed according to an operating scheme forming a cross section of said three-dimensional body, said three-dimensional product being formed by successive fusing together of successively formed cross sections from by the powder dispenser, and method for producing a three-dimensional product using such an arrangement.
Patent CA-2509470-A1 (CA)
Title: Method and apparatus for removal of non-uniformities in an electrophoresis apparatus
Inventor: HEFFELFINGER DAVID M
IPC: G01N27/447
Filed: 1998-02-26
Abstract: A method and apparatus for correct-ing the non-uniformities in the lens assem-bly of an electrophoresis apparatus is pro-vided. In one aspect, a look-up table is cre-ated based on non-uniformities at different aperture and magnification settings (Figure 5). In another aspect, a calibration standard with a uniform emittance is used to correct non-uniformities. In yet another aspect, a beam splitter or mirror is used to create a correction data file for non-uniformities in the light source.
Patent CA-2509478-A1 (CA)
Title: Process for conversion and size reduction of solid particles
Inventor: BERENDS EDWIN MARK
IPC: C01F7/785
Filed: 2003-12-02
Abstract: A combined process for the conversion of solid starting particles into solid intermediate particles and reducing the median diameter of the intermediate particles to obtain product particles. This process involves flowing a suspension of starting particles through a series of at least two conversion vessels, thereby converting at least part of the starting particles into intermediate particles, adding a supercritical fluid to one or more of the conversion vessels, thereby forming a supercritical suspension, and releasing pressure from the supercritical suspension, thereby expanding the suspension and converting the intermediate particles into product particles.
Patent CA-2511262-A1 (CA)
Inventor: CHESNA JOHN C
IPC: C09K19/38
Filed: 2004-01-21
Abstract: Thermotropic liquid crystalline polymer powders are melt molded under conditions where relatively little flow of the molten LCP occurs. This results in parts with isotropic properties, and which have relatively uniform coefficients of thermal expansion in all directions. These parts are useful, for example, in electrical and electronic applications, and with the addition of certain types of resins and/or fillers for wear parts.
Patent CA-2511986-A1 (CA)
Inventor: KEE SCOTT M
IPC: C07K14/81
Filed: 2003-12-19
Abstract: L'invention concerne un procédé simplifié de purification d'antitrypsine alpha-1 (AAT) à partir d'un mélange protéique contenant de l'AAT, tel qu'un précipité de fraction Cohn IV. Dans le procédé selon l'invention, des protéines contaminantes sont destabilisées par clivage de liaisons disulfure à l'aide d'un réactif réducteur, tel qu'un dithiol, lequel n'affecte pas l'AAT. Les protéines destabilisées sont ensuite de préférence adsorbées sur un matériau adsorbant de protéines solide, sans addition d'un sel en tant que précipitant. La séparation de l'adsorbant solide de la solution donne une solution d'AAT purifiée qui est directement utilisable pour la purification chromatographique, sans nécessiter de dessalage extensif tel que dans les procédés de la technique antérieure. L'invention concerne également un traitement faisant appel audit procédé, lequel donne de l'AAT de qualité pharmaceutique avec un rendement élevé à une échelle commerciale.
Patent CA-2513336-A1 (CA)
Title: Control of gene expression in a non-human eukaryotic cell, tissue or organ
Inventor: RICE ROBERT NORMAN
IPC: C12N15/85
Filed: 1999-03-19
Abstract: The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. Specifically, the invention provides an isolated nucleic acid molecule comprising two or more copies of a ribonucleotide (RNA) sequence which are about 20-100 nucleotides in length and wherein a first copy is at least 80% identical to the nucleotide sequence of a target gene or a region thereof, and at least a second copy is 80% identical to a nucleotide sequence complementary to the target gene or the region thereof, wherein said nucleic acid molecule is capable of reducing expression of the target gene in a mammalian cell when the nucleic acid molecule is introduced into said mammalian cell.
Patent CA-2514640-A1 (CA)
Inventor: ARONSTAM PETER S
IPC: G01V1/133
Filed: 2004-02-11
Abstract: A wellbore system and method for producing seismic waves in an earth formation. The system comprises a cavity containing fluid. The cavity is in a space between a wellbore tubular, which may be casing or production tubing, and the wellbore formation. A device is provided for generating pressure waves in the cavity at resonance frequencies of the cavity. The pressure waves generate seismic waves that radiate into the adjacent earth formation that may be recorded. The recorded seismic waves may be used to determine parameters of interest of the earth formation.
Patent CA-2514898-A1 (CA)
Title: Method for treating the surface of a part made of a heat-structured composite material and use thereof in brazing parts made of a heat-structured composite material
Inventor: THEBAULT JACQUES
IPC: C04B35/571
Filed: 2004-01-29
Abstract: A liquid composition containing a ceramic precursor polymer and a refractory solid charge is applied to the surface of the part to be treated. After cross-linking, the polymer is transformed into a ceramic by heat treatment and a ceramic deposit is then formed by chemical infiltration in a vapor phase. The surface of the part is leveled prior to chemical infiltration in a vapor phase in order to return to the initial geometry of the composite material part to be formed, by chemical infiltration in a vapor phase, a deposit obturating the residual microporosity on the leveled surface of the part.
Patent CA-2519046-A1 (CA)
Inventor: LEWIS-GRAY ALEXANDER HAMILTON
IPC: B04B11/06
Filed: 2004-03-04
Abstract: A centrifuge (1) for continuously separating a fluid stream into fractions of different density comprising: conduit means (17) for radially directing flow of the fluid stream, drive means (19, 22) for rotating the conduit means about an axis (19) whereby to subject the fluid stream to centrifugal force causing it to travel from a location in the conduit means nearer to the axis to a position further away from the axis, and a plurality of conduit outlets (35, 36, 37) from the conduit means arranged at different radial distances from the axis for taking off fractions of different density from the fluid stream.
Patent CA-2519287-A1 (CA)
Inventor: TSUTSUI TATSUO
IPC: A61M13/00
Filed: 2003-03-27
Abstract: An apparatus for applying powder medicine in the nasal cavity comprising a capsule containing/holding section (30) provided with a capsule inserting/drawing part (40), wherein cutters (60A, 60B) for cutting the opposite end parts of a capsule in the axial direction and boring the capsule are disposed on the opposite sides of the capsule draw-out part (40) of the capsule containing/holding section (30). A medicine capturing part (32) and a one-way valve (33) are provided at the lower part (38) of the capsule containing/holding part of the capsule containing/holding section (30) and a pump section (50) having an air intake valve (54) is provided on the air inflow side. A medicine spray section (20) is provided on the air outflow side of the capsule containing/holding section (30) and arranged with a nozzle (22) so that medicine in the capsule can be applied to the nasal cavity of a user by pressing the pump section (50).
Patent CA-2519694-A1 (CA)
Title: Methods for treating lower urinary tract disorders using smooth muscle modulators and alpha-2-delta subunit calcium channel modulators
Inventor: THOR KARL BRUCE
IPC: A61K45/06
Filed: 2004-03-22
Abstract: A method is provided for using .alpha.2.delta. subunit calcium channel modulators or other compounds that interact with the .alpha.2.delta. calcium channel subunit in combination with one or more compounds with smooth muscle modulatory effects to treat and/or alleviate the symptoms associated with painful and non-painful lower urinary tract disorders in normal and spinal cord injured patients. According to the present invention, .alpha.2.delta.  subunit calcium channel modulators include GABA analogs (e.g. gabapentin and pregabalin), fused bicyclic or tricyclic amino acid analogs of gabapentin, and amino acid compounds. Compounds with smooth muscle modulatory effects include antimuscarinics, .szlig.3 adrenergic agonists, spasmolytics, neurokinin receptor antagonists, bradykinin receptor antagonists, and nitric oxide donors.
Patent CA-2522610-A1 (CA)
Title: Method and system for aligning a stationary vehicle with an artificial horizon background
Inventor: HOAGLAN BRIAN S
IPC: B60G17/052
Filed: 2004-04-16
Abstract: A method of positioning a vehicle chassis of a stationary vehicle in approximate alignment with a predetermined datum is provided. The vehicle has an axle and a fluid suspension system. The fluid suspension system includes a control device, a pressurized fluid source and an exhaust passage. The pressurized fluid source and the exhaust passage are in fluid communication with the plurality of fluid suspension members through the control device. The vehicle also includes an electronic control unit operatively associated with the control device. The method including steps of providing an alignment sensor supported on the chassis for outputting a signal indicative of the orientation of the chassis to the electronic control unit and acquiring a signal output by the alignment sensor. Another step includes comparing the signal from the alignment sensor to alignment data stored in the electronic control unit. A further step includes selectively operating the control device to permit fluid communication between one or more of the fluid suspension members and one of the pressurized fluid source and the fluid exhaust until the signal from the alignment sensor approximately corresponds to the alignment data. A system for performing the method is also discussed.
Patent CA-2523081-A1 (CA)
Title: Macrolide-conjugates with anti-inflammatory activity
Inventor: HRVACIC BOSKA
IPC: C07J1/00
Filed: 2004-04-23
Abstract: The present invention relates to new compounds represented by Formula (I);  wherein M represents a macrolide subunit of the substructure II, Formula (II);  L represents the chain of the substructure III, Formula (III); D represents the steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity. The present invention relates also to pharmaceutically acceptable salts and solvates of such prepared compounds, to processe and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals.
Patent CA-2527210-A1 (CA)
Inventor: BLANCHARD ANDREW
IPC: G01S7/282
Filed: 2004-05-27
Abstract: A method of organizing a radar system or a sensor system with multiple levels of hierarchical constructs for all level of the system. These architectural levels incorporate self-similar organizational structure and represent design strategies that implement data transfer and communication interfaces with both intranet and internet communication network connections.
Patent CA-2528896-A1 (CA)
Title: Latching arrangement for a tonneau cover
Inventor: CUMBERLAND SCOTT
IPC: B62D33/04
Filed: 2005-12-06
Abstract: A tonneau cover assembly is provided for a bed of a pickup truck having a pair of spaced apart sidewalls. The tonneau cover assembly includes an elongated rail adapted to be fixedly secured to each of the pair of spaced apart sidewalls.  Each of the elongated rails includes a bottom member having at least one opening extending therethrough. A panel includes opposing ends slidably coupled to the elongated rails for selectively covering the bed. A retention member is fixedly secured to each of the opposing ends of the panel for slidingly engaging the elongated rails. Each of the retention members is receivable within the opening along one of the elongated rails to retain the panel in place along the elongated rails.
Patent CA-2530601-A1 (CA)
Inventor: GYSLING DANIEL L
IPC: G01F1/7082
Filed: 2004-06-24
Abstract: Système constitué d'un ou plusieurs débitmètres configurables, qui permet à une personne d'activer sélectivement, localement ou à distance, une ou plusieurs fonctions des débitmètres. Ladite personne est capable de sélectionner le paramètre du flux que le débitmètre doit mesurer, ce système fournissant ainsi des fonctions latentes qui peuvent être sélectivement activées ou désactivées. Ledit système peut également permettre à une personne d'activer sélectivement, localement ou à distance, un ou plusieurs débitmètres latents du système. Ce système peut être un système de commande réparti qui reçoit des signaux d'entrée de débitmètres et dispositifs classiques situés dans le flux et qui fournit des signaux de commande à un ou plusieurs dispositifs situés dans le flux. Ledit système peut également concerner un procédé de sélection et de facturation de débitmètre.
Patent CA-2530980-A1 (CA)
Inventor: WONG HING C
IPC: C07K16/00
Filed: 2004-06-04
Abstract: Disclosed are methods for preventing or treating sepsis, a sepsis-related condition or an inflammatory disease in a mammal. In one embodiment, the method includes administering to the mammal a therapeutically effective amount of at least one humanized antibody, chimeric antibody, or fragment thereof that binds specifically to tissue factor (TF) to form a complex in which factor X or factor IX binding to the complex is inhibited and the administration is sufficient to prevent or treat the sepsis in the mammal. The invention has a wide spectrum of useful applications including treating sepsis, disorders related to sepsis, and inflammatory diseases such as arthritis.
Patent CA-2533050-A1 (CA)
Title: Pallet-type conveyor system for hot metal-strip coils
Inventor: PESCHKE JUERGEN
IPC: B21B39/00
Filed: 2006-01-17
Abstract: A conveyor having an array of rollers defining a transport plane is used with pallets each having supports forming an upwardly open saddle adapted to hold a coil of metal strip, and a pair of generally parallel and longitudinally extending rails underneath and fixed to the supports. Each rail has a downwardly directed face adapted to ride directly on the rollers and having a generally planar center region and a pair of upwardly angled end regions each forming a small acute angle with the respective center region.
Patent CA-2533751-A1 (CA)
Title: Transparent migration of stateless sessions across servers
Inventor: KALUSKAR SANJAY
IPC: H04L29/06
Filed: 2004-08-13
Abstract: Techniques allow a client to be migrated from a session that has been established for a client on a server to another session on another server in a way that is a transparent to the application for which the initial session was established. The sessions are migrated under conditions in which a copy of session state of the session to migrate from the source node does not have to be captured and restored to a destination session.
Patent CA-2533874-A1 (CA)
Title: Improved transcutaneous power and/or data transceiver system
Inventor: WOODARD JOHN CAMPBELL
IPC: A61F2/48
Filed: 2004-07-30
Abstract: A device for communicating electric signals across the skin layer (1) of a patient, wherein the device includes: an electrically conductive core (2) capable of forming an EMF flux loop; first (3) and second (4) coils, which are in EMF communication with said electrical conductive core (2) and wherein the first coil (3) is positioned externally to the patient and surrounds at least a first portion of the electrically conductive core (2); and the second coil (4) is implanted beneath or in the skin layer and surrounds at least a second portion of the electrically conductive core.
Patent CA-2534648-A1 (CA)
Inventor: STRINGER IAN JAMES
IPC: A61F2/82
Filed: 2004-08-05
Abstract: The invention provides a method for the coating of a surgical device, wherein the coating is carried out by electrostatic Powder deposition. The device may be a device used in a surgical or diagnostic procedure, including interventional devices as well as implantable devices. Because the coating is applied electrostatically, it is attracted to all parts of the device, not just those parts that are in the 'line of sight' of the spray, as is the case with conventional liquid spray coating. The process allows uniform and reproducible amounts to be deposited and thus drug-eluting coatings can be accurately applied to stents and other surgical devices, resulting in good control over drug release. Furthermore, drug-eluting coats can be applied in a single step, although multiple layers can easily be applied if desired to create a specific drug release profile.
Patent CA-2536193-A1 (CA)
Title: Method and apparatus for irradiating fluids
Inventor: KAZEM BIJAN
IPC: A61L2/12
Filed: 2004-08-16
Abstract: A method and an apparatus (11) for treating fluids are provided. The method generally includes cavitating and irradiating a liquid. The irradiation of the liquid may include exposing the liquid to ultraviolet radiation. The apparatus generally includes a housing (12) having a chamber (15) formed therein and defined, at least in part, by a chamber wall that transmits radiation therethrough. The apparatus also includes a cavitator in flow communication with the interior of the chamber and a radiator (10) aligned to direct radiation into the interior of the chamber. Cavitation generated by the apparatus and/or provided in the method tends to refresh the liquid exposed to the radiation, thereby increasing the rate of radiation exposure for the liquid.
Patent CA-2536576-A1 (CA)
Title: Derivatives of hydroxamic acid as metalloproteinase inhibitors
Inventor: DAVIES STEPHEN JOHN
IPC: C07D213/36
Filed: 2004-08-18
Abstract: Compounds of formula (I) are inhibitors of matrix metalloproteinases, and are of use in the treatment of, for example fibrotic disease, multiple sclerosis, emphysemia, bronchitis and asthma: formula (I) wherein Ar represents an optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl or heterocycloakyl group; R represents hydrogen or C1-C6 alkyl, or C3-C6 cycloalkyl; Alk represents a divalent C1-C5 alkylene or C2-C5 alkenylene radical; and R1 and R2 taken together with the nitrogen atom to which they are attached form a first heterocycloalkyl ring which is optionally fused to a second C3-C8 cycloalkyl or heterocycloalkyl ring, the said first and second rings being optionally substituted by at least one group of formula (II): formula (II) wherein m, p and n are independently 0 or 1; Z represents, hydrogen, or an optionally substituted carbocyclic or heterocyclic ring of from 5 to 7 ring atoms which is optionally fused to another optionally substituted carbocyclic or heterocyclic ring of from 5 to 7 ring atoms; Alk1 and Alk2 independently represent optionally substituted divalent C1-C3 alkylene radicals; X  represents -0-, -S-, -S(O)-, -S(O2)-, -C(=O)-, -NH-, -NR3-, -S(O2)NH-, -S(O2)NR3-, -NHS(O2)-, or -NR3S(O2)-, where R3 is C1-C3 alkyl.