baber/WOPTO huggingface dataset:
Patent CA-2478374-C (CA)
Title: Utilisation de derives de benzimidazole alkyles n3 en tant qu'inhibiteurs de mek
Inventor: MARLOW ALLISON L
IPC: C07D403/06
Filed: 2003-03-13
Granted: 2009-01-06
Abstract: L'invention concerne des composés représentés par la formule (I) ainsi que des sels pharmaceutiquement acceptables et des promédicaments de ces derniers, où W, R?1¿, R?2¿, R?7¿, R?8¿, R?9¿ and R?10¿ sont tels que définis dans le descriptif. De tels composés sont des inhibiteurs de MEK et sont utiles au traitement de maladies hyperprolifératives, telles que le cancer et les inflammations, chez les mammifères. L'invention se rapporte également à un procédé d'utilisation de tels composés dans le traitement de maladies hyperprolifératives chez les mammifères, et à des compositions pharmaceutiques contenant de tels composés.
Patent CA-2482702-C (CA)
Inventor: FRANER PAUL T
IPC: A61B17/34
Filed: 2004-09-28
Granted: 2013-02-12
Abstract: A trocar housing for a trocar assembly includes a first housing member selectively coupled to a second housing member, wherein the first and second housing members include aligned apertures shaped and dimensioned for passage of an instrument therethrough.  The trocar housing also includes a rotary latch mechanism selectively coupling the first housing member and the second housing member. The rotary latch mechanism includes a latching member which rotates relative to the first and second housing members about a longitudinal axis of the housing member for selectively coupling the first and second housing members.
Patent CA-2484038-C (CA)
Inventor: DININNO FRANK P
IPC: A61P29/00
Filed: 2003-04-18
Granted: 2011-10-18
Abstract: La présente invention concerne des composés et leurs dérivés, leur synthèse et leur utilisation en tant que modulateurs de récepteurs d'oestrogène. Les composés selon l'invention se présentent sous la forme de ligands de récepteurs d'oestrogène et servent en tant que tels au traitement ou à la prévention de divers troubles impliquant les oestrogènes : perte osseuse, fracture osseuse, ostéoporose, dégénérescence cartilagineuse, endométriose, maladies fibroïdes utérines, bouffées de chaleur, taux élevés de cholestérol LDL, maladies cardiovasculaires, déficience des fonctions cognitives, troubles dégénératifs cérébraux, resténose, gynécomastie, prolifération de cellules des muscles lisses de la paroi vasculaire, obésité, incontinence, et cancer notamment du sein, de l'utérus et de la prostate.
Patent CA-2491705-C (CA)
Title: Method for the production of transgenic plants with increased virus resistance by silencing vegetable dnaj-like proteins
Inventor: HOFIUS DANIEL
IPC: A01H5/00
Filed: 2003-07-21
Granted: 2014-06-17
Abstract: The invention relates to plants and plant cells which have a transient or permanent virus resistance as a result of modulation of the gene expression and/or binding behaviour of vegetable DnaJ-like proteins. The invention also relates to a method for the production of transgenic plants with increased virus resistance, wherein the expression of vegetable DnaJ-like proteins which interact with viral components is substantially prevented by silencing the DnaJ-like proteins. The invention further relates to a method for the production of transgenic plants with increased virus resistance, wherein the interaction of viral components with vegetable DnaJ-like proteins is substantially prevented by expression of dominant-negative mutants of the DnaJ-like proteins, by antibodies against DnaJ-like proteins or by specific inhibitors.
Patent CA-2495670-C (CA)
Title: Remote ordering device
Inventor: PENTEL RANDOLPH M
IPC: G06Q30/00
Filed: 2003-08-15
Granted: 2007-12-04
Abstract: A remote ordering device (10) for placing orders though cell phones or other data entry and wireless transmission devices (12) and a data receiving station (14) to receive the data, process the orders and keep track of accounts, inventory and retain other data as required. The receiving station can be in communication with other receiving stations to forward orders or data. The receiving station can provide instructions to a person or machine to fill orders at any desired location. The instructions may be printed out or displayed on a screen (36). A GPS, WAP or other location finding systems, may be used to identify the user's location. Bioelectronics, Caller I.D., pin numbers or other identification means can be used to verify the user for debiting accounts or credit cards. Users can remotely order tickets, meals, services, or control machines remotely and either arrange for pick up at a desired location or for delivery.
Patent CA-2498634-C (CA)
Title: A process for the preparation of drospirenone
Inventor: CONSTANTINO FRANCESCA
IPC: C12P33/20
Filed: 2005-02-28
Granted: 2012-03-20
Abstract: A process is described for preparing drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for the preparation of pharmaceutical compositions with contraceptive action, starting from 5,6.beta.-epoxy-7.beta.-hydroxy-15.beta.,16.beta.-methylene-3.beta.- pivaloyloxy-5.beta.-androstan-17- one.
Patent CA-2502062-C (CA)
Title: Methode et appareil pour appliquer un materiau particulaire a un substrat
Inventor: FUNG PAUL Y
IPC: A61F13/15
Filed: 2005-03-23
Granted: 2013-07-09
Abstract: Une méthode et un appareil pour appliquer un matériau particulaire sur un substrat comprennent l'application d'un adhésif sur le substrat et le passage du substrat dans une chambre dans laquelle un matériau particulaire est suspendu dans un fluide, pour faire adhérer le matériau particulaire au substrat.
Patent CA-2508959-C (CA)
Inventor: AGARWAL SAMEET H
IPC: G06F17/00
Filed: 2004-07-27
Granted: 2014-07-15
Abstract: The present invention relates to a system and methodology to facilitate security for data items residing within (or associated with) a hierarchical database or storage structure. A database security system is provided having a hierarchical data structure associated with one or more data items. The system includes a security component that applies a security policy to the data items from a global location or region associated with a database. Various components and processes are employed to enable explicit and/or inherited security properties to be received by and propagated to the data items depending on the type of data structure encountered or processed.
Patent CA-2518944-C (CA)
Title: Inhibiteurs de proteines de choc thermique (hsp90) extracellulaires
Inventor: JAY DANIEL G
IPC: A61K31/37
Filed: 2004-03-09
Granted: 2013-07-30
Abstract: La présente invention a trait à des inhibiteurs de protéines de choc thermique 90 (Hsp90) extracellulaires. L'inhibition des Hsp90 entraîne la réduction du caractère envahissant de cellules tumorales. L'invention a également trait à l'utilisation de molécules inhibitrices de la fonction des Hsp90 extracellulaires pour la fabrication d'un médicament pour le traitement ou la prévention d'invasion et/ou de potentiel métastatique de cellules cancéreuses.
Patent CA-2535187-C (CA)
Inventor: MCDANIEL PATRICK
IPC: H04L12/26
Filed: 2006-02-03
Granted: 2010-03-23
Abstract: The current invention relates to a system and method for tracking or locating a target entity on a data network, such as the public Internet, by analyzing network traffic and communication among interacting network nodes. The invention describes a system of creating an information set of data related to the traffic patterns associated with a specific entity over a time period, and comparing the information set to other information related to the traffic patterns associated with a group of entities over the same time period. By excluding information that is common to both the specific entity and the group of entities from the information set, the information set is left with only the information that helps identify the specific entity on the network.
Patent CA-2535770-C (CA)
Inventor: MERUELO DANIEL
IPC: C12N15/63
Filed: 2004-08-17
Granted: 2013-10-01
Abstract: Disclosed herein are methods for identifying cancer cells and monitoring anticancer therapy in the body of a mammal by systemically delivering Sindbis viral vectors. The vector can specifically target and identify tumor cells in mice growing subcutaneously, intraperitoneally, intrapancreatically, or in the lungs. These findings demonstrate the remarkable specificity of the Sindbis vector system that is relatively safe and can specifically target tumor cells throughout the body via the bloodstream.
Patent CA-2541276-C (CA)
Title: Processes and apparatuses for applying a benefit composition to one or more fabric articles during a fabric enhancement operation
Inventor: DUVAL DEAN LARRY
IPC: D06F34/04
Filed: 2004-10-27
Granted: 2010-04-06
Abstract: A process is provided for applying a benefit composition to a fabric article during a fabric enhancement operation. The process may comprise the steps of selecting a desired one of two or more levels of a benefit to be provided by the benefit composition to the fabric article, and selecting one dosage amount for the benefit composition based on the selected benefit level.
Patent CA-2542935-C (CA)
Title: Additive mixture as component of a mineral oil composition
Inventor: HAUBOLD WOLFGANG
IPC: C10L1/22
Filed: 2004-10-15
Granted: 2009-11-10
Abstract: An additive mixture as component of a composition of mineral oil as main component and trace portions of an additive mixture containing the additive components a) ethylene-vinylester copolymers modified by polar groups with molecular mass weight averages from 3000 to 50000 and an ethylene component of 50 to 90 mass %, and b) C2-C6-oxyalkyl-bridged C12-C40-monocarboxylic acids, and/or c) partially and/or completely imidated copolymers of unsaturated C4-C20-dicarboxylic acid anhydrides and vinyl aromatics and/or C2-C36-.alpha.-olefins, whereby the content of the additive mixture in the mineral is 0.005 to 1 mass %.     The compositions are suitable as flowable media to be transported at low temperatures and as mineral oil fuels with high lubricity and flowability.
Patent CA-2543375-C (CA)
Inventor: WOLLENBERG ROBERT H
IPC: G01N33/03
Filed: 2004-10-27
Granted: 2013-05-28
Abstract: A method for determining oxidation stability for a plurality of different lubricating oil composition samples (212) is provided. The methods can advantageously be optimized using combinatorial chemistry, in which a database of combinations of lubricating oil compositions is generated. As market conditions vary and/or product requirements or customer specifications change, conditions suitable for forming desired products can be identified with little or no downtime.
Patent CA-2545789-C (CA)
Title: Spherical pearlescent pigment concentrate comprising a wax and a surfactant
Inventor: WILLARD CHARLES J
IPC: C08F8/06
Filed: 2004-11-24
Granted: 2012-08-07
Abstract: The present invention provides a substantially spherical composition comprising about 60 to 80 percent by weight pearlescent pigment, 14 to about 38 percent by weight wax, and about 2 percent to 6 percent surfactant. This composition is particularly useful for extrusion into any polymer used for masterbatching. The masterbatch is then typically blow or injection molded or extruded into a finished part.
Patent CA-2547055-C (CA)
Inventor: FIDJELAND ARNT HELGE
IPC: C25C3/12
Filed: 2004-11-15
Granted: 2012-01-24
Abstract: The present invention concerns a method and equipment for replacing anodes in an electrolysis cell in which a crane with an anode gripper is used to lift out used anodes and to insert new anodes. The new anode is inserted at a height in accordance with a calculated height based on the height of the anode removed, the height of the anode removed and the height of the new anode being measured against a common reference level. Laser-based measuring equipment is arranged between a point on the crane, which is stationary in terms of height during the operation, and a point on the anode gripper, which moves together with the anode, and measures the heights stated. The measured values are processed by a PLC-based system, which determines a more precise insertion height of the new anode in accordance with a specific algorithm.
Patent CA-2552519-C (CA)
Inventor: CAMERON ALLAN
IPC: A61G15/12
Filed: 2005-01-06
Granted: 2014-05-06
Abstract: A device provides simple positioning of the patient's head and simple positioning of the TMS coil relative to a coordinate system of the patient's head once the head is positioned.  The TMS coil is fixed at a treatment position in the coordinate system of the patient's head and the position in the coordinate system is recorded for use in subsequent clinical sessions. A positioner assembly supports the weight of the TMS coil and allows the operator to freely move the TMS coil to search for the patient's motor threshold position (MTP) and/or the treatment position (TXP). If the TXP is in registration with the MTP, once the MTP is determined, the positioner assembly requires only a single adjustment of the magnet position to locate the TXP where the coil is locked in place for the duration of the TMS therapy.
Patent CA-2555045-C (CA)
Inventor: HELLER PATRICK ALEXANDER
IPC: F16K27/12
Filed: 1999-12-22
Granted: 2009-04-07
Abstract: An air flow control valve including: a valve body having an internal cavity and an inlet and outlet in flow communication with the internal cavity, the axes of the inlet and outlet being aligned at substantially 90° to each other; a valve seat located within the cavity and co-axially aligned with the outlet, the valve seat being located on the distal end of an upstanding tubular pedestal which is formed around the outlet; the internal cavity being configured so as to define an annular space around the pedestal with which the inlet is in flow communication; a flexible generally planar diaphragm mounted above the valve seat, the diaphragm supporting a valve closure member which is adapted to engage the valve seat to close the valve; valve control means for causing the diaphragm to move towards and away from the valve seat to close and open the valve respectively; and the valve being characterized in that, with the valve oriented with the inlet axis horizontal and the outlet facing downwards, the valve seat is located at an elevation at or below the upper most edge of the inlet, and the diaphragm is located at an elevation above the upper most edge of the inlet.
Patent CA-2557552-C (CA)
Title: Concave composition carrier for multiple use fabric conditioning article
Inventor: TRINH TOAN
IPC: D06L1/00
Filed: 2005-02-25
Granted: 2010-11-02
Abstract: A multiple use fabric conditioning article comprising a concave composition carrier to which a fabric conditioning composition is operatively attached is disclosed.  The present invention produces a substantially planar or flat composition carrier after the addition of a fabric conditioning composition, which warps due to shrinkage when cooled, thereby improving the impression of the product and the mating of connecting elements of the fabric conditioning article.
Patent CA-2558959-C (CA)
Title: Device and method for detecting the presence of hemoglobin in a biological sample
Inventor: CHANDLER HOWARD MILNE
IPC: G01N33/72
Filed: 2005-04-29
Granted: 2014-11-04
Abstract: A device and method for detecting the presence of hemoglobin in a biological sample, more particularly, the presence of blood in a fecal sample as an indicator of upper or lower gastrointestinal tract bleeding.
Patent CA-2559546-C (CA)
Title: Methode pour un dimensionnement optimal des cellules d'appareils de chromatographie de partition centrifuge
Inventor: FOUCAULT ALAIN
IPC: G01N30/42
Filed: 2005-03-17
Granted: 2014-06-03
Abstract: Méthode pour dimensionner les cellules d'une « colonne » de chromatographie liquide-liquide centrifuge (colonne CPC) constituée de disques empilés, sur lesquels sont gravés les cellules reliées en cascade (en série) par des petits canaux. La rotation de la pile crée un champ d'accélération centrifuge important qui permet de maintenir immobile une phase liquide, dite stationnaire, tandis qu'une phase mobile circule le long de la colonne CPC. Les cellules sont tridimensionnelles avec deux dimensions (L, 1) des cellules étant orientées dans un plan sensiblement normal à l'axe de rotation (.OMEGA.) du disque et une troisième dimension (e) qui est dirigée selon une direction sensiblement parallèle à l'axe de rotation, et que l'on choisit de façon qu'elle soit au moins égale à l'une des deux autres dimensions (L, 1), ce qui procure une meilleure efficacité. Quand on doit changer l'échelle des appareils, on modifie la taille des cellules en veillant dans tous les cas à privilégier cette troisième dimension (e) qui doit être la plus grande possible. - Applications à la conception d'appareils de chromatographie analytique ou préparative.
Patent CA-2560782-C (CA)
Inventor: FISCHER TIMOTHY J
IPC: G01N33/53
Filed: 2005-03-23
Granted: 2013-05-21
Abstract: Methods and compositions for identifying high-grade cervical disease in a patient sample are provided. The methods of the invention comprise detecting overexpression of at least one biomarker in a body sample, wherein the biomarker is selectively overexpressed in high-grade cervical disease. In particular claims, the body sample is a cervical smear or monolayer of cervical cells. The biomarkers of the invention include genes and proteins that are involved in cell cycle regulation, signal transduction, and DNA  replication and transcription. In particular claims, the biomarker is an S-phase gene. In some aspects of the invention, overexpression of a biomarker of interest is detected at the protein level using biomarker-specific antibodies or at the nucleic acid level using nucleic acid hybridization techniques. Kits for practicing the methods of the invention are further provided.
Patent CA-2561816-C (CA)
Inventor: DUNN MICHAEL H
IPC: G06F3/0484
Filed: 2005-04-01
Granted: 2013-12-24
Abstract: A presentation method and system for presenting information to an audience within a space that mimics a flip chart assembly, the system including a control interface, a communication network and a master presentation unit including a processor and a master display screen, the master screen juxtaposed within the space so as to be viewable by the audience within the space, the processor operable to transmit an image displayed on the master screen over the network upon user command and a slave presentation unit including a slave presenter operable to receive and present an image to the audience within the space that is transmitted by the master unit to the slave unit over the network such that the master unit can be used to create a new image while the first image is simultaneously presented.
Patent CA-2565577-C (CA)
Title: System and method for provisioning a third party mobile device emulator
Inventor: HASSAN MAHMUD-UI
IPC: H04M1/72406
Filed: 2006-10-25
Granted: 2012-02-28
Abstract: A method and apparatus for provisioning a third party mobile device emulator from desktop provisioning software, the method having the steps of: designating a common file space between the third party mobile device emulator and the desktop provisioning software; writing files to the common file space from one of the third party mobile device emulator and the desktop provisioning software; and reading the files from the other of the third party mobile device emulator and the desktop provisioning software.
Patent CA-2572166-C (CA)
Title: Utilisation de composes de polyoxyalkylene en tant qu'ameliorants de la reponse de la fluidite a froid dans du mazout contenant un detergent, composition d'additif convenant a une telle utilisation et mazout contenant ledit additif
Inventor: KRULL MATTHIAS
IPC: C10L1/22
Filed: 2006-12-21
Granted: 2014-01-14
Abstract: L'invention concerne l'utilisation d'au moins un composé polyoxyalkylène soluble dans l'huile. Ce composé polyoxyalkylène étant un ester, un éther ou un éther/ester soluble dans l'huile de polyols alkoxylé comporte au moins trois unités d'alkoxy de répétition dérivées d'oxydes d'alkylène ayant de 2 à 5 atomes de carbone par groupe OH du polyol, qui porte au moins deux radicaux d'hydrocarbures aliphatiques ayant de 12 à 30 atomes de carbone servant à améliorer le comportement de réponse des améliorants du fluage de l'huile minérale, dans des distillats moyens. Ces améliorants comprennent au moins un additif détergent contenant de l'azote, mais pas de cendres, qui est un composé amphiphile soluble dans l'huile comportant au moins un radical alkyle ou alkényle lié à un groupement polaire, le radical alkyle ou alkényle comprenant de 10 à 500 atomes de carbone et le groupement polaire comportant 2 atomes d'azote ou plus.
Patent CA-2574455-C (CA)
Inventor: DEBES MICHAEL H
IPC: B01D39/16
Filed: 2005-07-22
Granted: 2009-12-15
Abstract: In one aspect, the invention provides an article consisting essentially of a paper layer including about 10 Wt% to about 40 Wt% of a thermoplastic polymer and an ePTFE membrane laminated to the paper layer. Preferably, the paper layer includes about 10 Wt% to about 30 Wt% of a thermoplastic polymer. More preferably, the paper layer includes about 18 Wt% to about 25 Wt% of a thermoplastic polymer. A paper layer including about 20 Wt% of a thermoplastic polymer is most preferred. In another aspect, the thermoplastic polymer may comprise poly vinyl acetate. In yet another aspect, the invention provides a filter media consisting essentially of a cellulose paper layer including about 20 Wt% poly vinyl acetate binder; and an ePTFE membrane laminated to said cellulose paper layer. In still another aspect, the invention provides a paper layer in which the paper is cellulose paper. In yet another aspect, the invention provides a method of making a filter media consisting essentially of: providing a cellulose paper layer including about 20 Wt% of poly vinyl acetate, providing an ePTFE membrane to at least one surface of the cellulose paper layer; and laminating the ePTFE membrane to the cellulose paper layer.
Patent CA-2575912-C (CA)
Inventor: WANG ZHI-XIAN
IPC: C07D209/42
Filed: 2004-11-22
Granted: 2011-10-11
Abstract: Processes for: a) separating the enantiomers of indoline-2-carboxylic acid of formula 1 (see formula 1) comprising of: (i) combining the (R, S)-indoline-2-carboxylic acid with (1S)- or (1R)-10-camphorsulfonic acid as the resolving agent in a resolution solvent and crystallizing from the said mixture the diastereomeric salt of (S)- or (R)-indoline-2-carboxylic acid with optically pure (1S)- or (1 R)-10-camphorsulfonic acid; (ii) regenerating the (S)- or (R)-indoline-2-carboxylic acid from the crystallized diastereomeric salt by using a suitable base or basic ion-exchange resin;   and b) for the optical resolution of N-acetyl-indoline-2-carboxylic acid of formula 2 (see formula 2) comprising of: (i) combining the (R, S)-N-acetyl-indoline-2-carboxylic acid with (S)- or (R)-phenylglycinol as the resolving agent in a resolution solvent and crystallizing from the said mixture the diastereomeric salt of (S)- or (R)-N-acetyl-indoline-2-carboxylic acid with optically pure phenylglycinol; (ii) regenerating the (S)- or (R)-N-acetyl-indoline-2-carboxylic acid from the crystallized salt by using a suitable acid or acidic ion-exchange resin.   The non-selected enantiomer may then be racemized and the process (a) or (b) repeated thus to obtain substantial conversion of the material to one enantiomer.