baber/WOPTO huggingface dataset:
Patent KR-20110116209-A (KR)
Inventor: CABASSE GILBERT
IPC: H04L12/56
Filed: 2010-02-01
Abstract: 방문하는 사용자와 방문되는 사용자의 각각의 단말들(TC)이 패킷 네트워크(RP)를 통해 접속된 서버(SC)에 의해 관리되는 가상 환경 내의 각각 상이한 가상 공간들 내에 초기에 존재하는 방문되는 사용자와 방문하는 사용자 간에 멀티미디어 통신을 확립하기 위해, 서버는, 방문되는 사용자가 존재하고 있는 공간에 대한 액세스를 제공하는 가상 공간 내의 방문하는 사용자의 가상 이동 이후, 방문하는 사용자와 방문되는 사용자 간에 비디오 통신을 확립하고, 방문되는 사용자가 존재하고 있는 공간 내의 방문하는 사용자의 가상 이동 이후, 방문되는 사용자와 방문하는 사용자 간에 오디오 통신을 확립한다.
Patent KR-20120037369-A (KR)
Inventor: FUKUMITSU KENSHI
IPC: B23K26/067
Filed: 2010-08-06
Abstract: 개질스폿의 제어성을 향상시킨다. 레이저 가공장치(100)는 제1 펄스레이저광(L1)을 출사하는 제1 레이저광원(101)과, 제2 펄스레이저광(L2)을 출사하는 제2 레이저광원(102)과, 펄스레이저광(L1, L2)의 편광방향을 각각 변화시키는 1/2파장판(104, 105)과, 편광방향이 변화된 펄스레이저광(L1, L2)을 각각 편광분리하는 편광 빔스플리터(106, 107)와, 편광분리된 펄스레이저광(L1, L2)을 가공대상물(1)에 집광시키는 집광렌즈(112)를 구비하고 있다. 레이저 가공장치(100)에서는 광강도제어부(121)에 의해 1/2파장판(104, 105)에서 변화시키는 펄스레이저광(L1, L2)의 편광방향이 가변되면, 편광 빔스플리터(106, 107)에서 편광분리하는 펄스레이저광(L1, L2)의 비율이 가변되고, 그 결과, 펄스레이저광(L1, L2)의 각 강도가 조정된다.
Patent KR-20120016136-A (KR)
Inventor: CUDAK MARK C
IPC: H04W16/02
Filed: 2010-05-11
Abstract: OFDM 통신 시스템(100)에서, 주파수 대역폭은 다수의 물리 리소스 유닛들(PRUs)로 분할되고, 다수의 통신 가능 구역들에서 사용되기 위한 물리 층을 구성하는 주파수 분할 구성 모듈(FPCM)(118)이 제공된다.  FPCM은 PRU들을 주파수 선택 할당을 위한 제1 그룹, 및 주파수 다양성 할당을 위한 제2 그룹으로 분할한다(504).  FPCM은 2 그룹들 각각을 PRU들의 다수의 집합들로 더 분할하며(506), 인접 세그먼트 할당을 위해 할당된 연속 PRU들(CS-PRUs)에 제1 그룹으로부터의 PRU들의 집합들을 매핑하고(510), 분산 세그먼트 할당을 위해 할당된 연속 PRU들(DS-PRUs)에 제2 그룹으로부터의 PRU들의 집합들을 매핑한다(512).  FPCM은 DS-PRU들을 치환하고(514), CS-PRU들 및 치환된 DS-PRU들을 적어도 하나의 주파수 부분에 할당한다(518).
Patent KR-20120046113-A (KR)
Inventor: MCGEE JOHN D
IPC: C09D5/08
Filed: 2010-05-17
Abstract: 본 발명은 금속 기재에 대한 요구 대응 방출형 부식 억제 조성물로서, 비-전기 전도성 막 형성 코폴리머(들); 피리딘, 디하이드로피리딘, 피롤, 이미다졸, 또는 이것들의 혼합물을 포함하는 질소 함유 작용기 X; 및 메탈레이트 음이온으로부터 형성된 조성물에 관한 것이다.  메탈레이트 음이온은 이온 쌍 형성에 의해 작용기 X 중의 질소에 결합한다.  pH의 국소적 상승이 양성자 첨가/양성자 제거 반응을 통해 음이온의 방출을 일으키고, 방출된 음이온이 부식 형성을 억제하는 것으로 생각된다.  상기 코팅 조성물은 전기 전도성 폴리머를 포함하지 않는다.
Patent KR-20120036312-A (KR)
Inventor: WU WEISHI
IPC: H01L51/50
Filed: 2010-05-19
Abstract: 본 발명은 전계발광 용도에 유용한 크라이센 화합물에 관한 것이다.  본 발명은 또한 활성 층에 이러한 크라이센 화합물이 포함되는 전자 소자에 관한 것이다.
Patent KR-20120099179-A (KR)
Inventor: SCROCCHI ROBERTO
IPC: A61P31/12
Filed: 2010-06-24
Abstract: 촉매적 양의 아연 염과 촉매적 양의 바이덴테이트 포스핀을 갖는 팔라듐 복합체의 존재 하에 할로피리딘과 아릴마그네슘 할라이드를 아릴-아릴 크로스-커플링 반응시킴으로써 아릴피리딘의 제조하는 방법에 대한 것이다. 상기 아연 염은 바람직하게는 ZnCl 2 , ZnBr 2  및/또는 Zn(OAc) 2  로부터 선택되고, 상기 바이덴테이트 포스핀을 갖는 팔라듐 복합체는 바람직하게 (1,2-비스(디페닐포스피노)에탄)팔라듐(II) 클로라이드, (1,3-비스(디페닐포스피노)프로판)팔라듐(II) 클로라이드 및 (1,4-비스(디페닐포스피노)부탄)팔라듐(II) 클로라이드로 이루어진 그룹으로부터 선택된다. 가장 바람직한 것은 (1,2-비스(디페닐포스피노)에탄)팔라듐(II) 클로라이드이다. 이에 의해, 상기 아릴마그네슘 할라이드에 대해 계산된 95% 이상의 몰 수율 및 1:1500 이하의 촉매성을 얻는 것이 가능하다. 특히 상기 공정은 효과적으로 N1-(t-부톡시카르보닐)-N2-[4-(2'-피리딜)벤질]히드라진로 전환될 수 있는 4-(2'-피리딜)벤즈알데히드의 제조에 적합하다.
Patent KR-20130081767-A (KR)
Title: Thermo-reduction apparatus for manufacturing magnesium and method for manufacturing magnesium using the same
Inventor: PIAO RILONG
IPC: C22B26/22
Filed: 2012-01-10
Abstract: PURPOSE: A thermal reduction device for manufacturing magnesium and a magnesium manufacturing method using the same are provided to improve the efficiency of producing magnesium, to make a vacuum thermal reduction reaction easy, and to make the inflow of magnesian steam into condensers easy. CONSTITUTION: A thermal reduction device for manufacturing magnesium includes a thermal reduction furnace (400), a thermal reduction reaction pipe (410), condensers (500), and a vacuum pump (600). The thermal reduction furnace heats a green compact briquette in which calcined dolomite, ferrosilicon, and fluorite powder are mixed. The thermal reduction reaction pipe is a cylindrical retort in which a vacuum thermal reduction reaction is performed by being heated by the thermal reduction furnace. The condensers alternately condense the magnesian steam generated in the thermal reduction reaction pipe. The vacuum pump makes the insides of the condensers vacuous.
Patent KR-20120087828-A (KR)
Title: Flow sensors having a flow duct in the cover, and sensor tip as intermediate product
Inventor: MUZIOL MATTHIAS
IPC: G01P5/02
Filed: 2012-01-18
Abstract: PURPOSE: A flow sensor, and a sensor tip as an intermediate product are provided to massively produce anemometers for EGR(exhaust gas recirculation). CONSTITUTION: A heating resistor constitutes a sensor tip(3) as a film resistor(30). The self-supporting electrical conductor(42) is connected to the heating resistor and is fixed to a carrier. A cable(7) is introduced within a housing(6). The self-supporting electrical conductor passes through a cover housing(5). The conductor(71) of the cable is connected to the self-supporting electrical conductor. The housing is closed by a housing cover.
Patent KR-20130084946-A (KR)
Inventor: KANG TOO HWAN
IPC: A63F13/285
Filed: 2012-01-18
Abstract: PURPOSE: A regulator is provided to be connected about the special signal in which for game use active simulator is received from hardware device which is the game system instrument like the computer according to the content of the game besides the forwarding function of wire and wireless system by the specific signal input or the situation of the simple control key or since the player arbitrarily manipulates the regulator the situation fitting for the game characteristic can be directly felt about the regulation result to hand. CONSTITUTION: In order to be rotated on the surface of the rotator described in the above the wheel mounted on the upper body described in the above is equipped.
Patent KR-20130085777-A (KR)
Title: Pot control system using a load cell
Inventor: CHANG PYUNG SOON
IPC: A47J27/21
Filed: 2012-01-20
Abstract: PURPOSE: An electric pot control system using load cell is provided to control the filtered water and power source provided from a flow-power control unit to a port, thereby preventing the waste of resource. CONSTITUTION: An electric pot control system using load cell includes a main body and a flow-power control unit (20). The main body has a storing space in which a port is stored. The flow-power control unit controls the flow rate of the port and the power source that is applied to the port. The flow-power control unit includes a standard setting unit (21), a flow rate controlling unit (22), and a port power controlling unit (23). The standard setting unit sets the standard on the weight information of the port. The flow-power control unit controls the filtered water that is discharged from the main body based on the weight information which is set in the standard setting unit. The port power controlling unit controls the power that is supplied from the main body based on the weight information which is set in the standard setting unit. [Reference numerals] (21) Standard setting unit; (22) Flow rate controlling unit; (23) Port power controlling unit; (24) Storage unit; (AA) Input 1; (BB) Input 2; (CC) Filtered water; (DD) Port power
Patent KR-20130094102-A (KR)
Title: 의료 기기 제어 시스템 및 그 방법
Inventor: CHO JEONG HUN
IPC: G06Q50/22
Filed: 2012-02-15
Abstract: 의료 기기 제어 시스템이 개시된다. 본 시스템은, 대상체의 생체 신호를 센싱하는 센서, 대상체에 대한 특성 정보가 저장된 저장부, 센서로부터 생체 신호를 수신하여 분석하는 신호 처리부, 특성 정보 및 신호 처리부의 분석 결과에 따라 대상체에 대한 처방 내용을 결정하고, 대상체에 대응되는 의료 기기를 처방 내용에 따라 제어하는 제어부를 포함한다. 이에 따라, 환자 관리를 용이하고 신속하게 할 수 있다.
Patent KR-20130104252-A (KR)
Title: Obu compatible with t-money card
Inventor: GO JAE SOO
IPC: G06K19/07
Filed: 2012-03-13
Abstract: PURPOSE: A T-money card interoperation method in a vehicle mount device is provided to improve the user convenience or the system efficiency without modifying an infrastructure of a high way business office. CONSTITUTION: A dedicated short range communication (DSRC) communication unit receives a toll settlement request signal from a road side unit (S101). A control unit judges whether a detected payment unit is a T-money card or a high-pass card (S102,S103). The DSRC communication unit transmits vehicle information or high-pass card information stored in a storage unit to the road side unit when the control unit detects a high-pass card as a payment unit (S104). The DSRC communication unit transmits vehicle information or high-pass card information stored in a storage unit to the road side unit when the control unit detects a T-money card as a payment unit (S107). The control unit receives an authentication result or a settlement result from the road side unit (S105,S108) and approves passage of a corresponding vehicle when the authentication or settlement process is normally performed (S106,S109) (S110). [Reference numerals] (AA) Start; (BB) End; (S101) Receive a settlement request signal; (S102) Detect a payment means; (S103) Is the payment means a Hi-pass card ?; (S107,S104) Transmit information about a vehicle and a card; (S108,S105) Verify the vehicle and a user; (S109,S106) Calculate the amount of a charge and settle it; (S110) Permit the vehicle's entry
Patent KR-20130104865-A (KR)
Title: Communication modem and method of controlling the same, electric apparatus
Inventor: JANG BONG MUN
IPC: H04L47/80
Filed: 2012-03-15
Abstract: PURPOSE: A communication modem, a controlling method thereof, and an electrical appliance are provided to increase a communication possibility by including a plurality of communication units which use different communication methods. CONSTITUTION: A communication modem (140) includes a first communication unit (150) and a second communication unit (160). The first communication unit communicates with a first communication method. The second communication unit communicates with a communication method which is different from the first communication method. The first communication unit and the second communication unit are installed on the different corners of a printed circuit board. A component control unit (100) controls the function of an electrical appliance (10). A manipulating unit (110) inputs the operation instruction of the electrical appliance. [Reference numerals] (100) Component control unit; (110) Manipulating unit; (120) Display unit; (130) Load; (150) First communication unit; (160) Second communication unit
Patent KR-20130106068-A (KR)
Title: Nozzle pack and electrospinning device comprising the same
Inventor: KIM KWAN WOO
IPC: D04H1/728
Filed: 2012-03-19
Abstract: PURPOSE: A nozzle pack for electrospinning is provided to form a stable Taylor cone by maintaining constant pressure and solution flow of a spinning solution and inducing a magnetic field. CONSTITUTION: A nozzle pack for electrospinning comprises: a coil pipe which supplies a spinning solution through a coil-shaped pipe and induces a magnetic field when voltage is applied; and a nozzle connected to the coil pipe for electrospinning. The number of active coils is from 2 to 30. The inner diameter of the coil pipe is greater than or equal to 1mm. The diameter of the nozzle is greater than or equal to 6mm, and the ratio to the diameter of the coil pipe is greater than or equal to 0.2.
Patent KR-20130107660-A (KR)
Title: The method for making a low-salt dried yellow corvina using phellinus linteus
Inventor: PARK CHANG HA
IPC: A23L17/00
Filed: 2012-03-22
Abstract: PURPOSE: A production method of low salinity dried croaker is provided to produce the dried croaker with excellent storage property without fishy smell and decomposing smell. CONSTITUTION: Phellinus linteus, molokhia, ginger, and rice straws are dried into the water content within 5%, and are crushed into 5-10 um. The crushed Phellinus linteus, molokhia, ginger, and rice straws are mixed in a volume ratio of 60:20:10:10. The mixed powder is mixed with purified water in a volume ratio of 50:50. The mixture is fermented at 25-40°C for 3-15 days. The fermented material and purified water are mixed in a weight ratio of 1:2, and the material is extracted for 1-3 hours at a low temperature of 40-55°C. The extract is filtered and cooled at 10-20°C. The cooled extract is mixed with salt to obtain an aging solution with the salinity of 10-15%. Croaker is dipped in the aging solution, and aged for 5-20 hours. The croaker is dried, and tied with the rice straws before drying at 30-35°C into the water content of 32-50% using hot air.
Patent KR-20130110457-A (KR)
Title: Detecting apparatus for taking vehicle information and treadle apparatus for taking vehicle information having the same
Inventor: KIM YUN OCK
IPC: G08G1/02
Filed: 2012-03-29
Abstract: PURPOSE: A sensing device for obtaining vehicle information and a treadle device for obtaining vehicle information including the same reduce maintenance costs by preventing abrasion even after repeated use. CONSTITUTION: A sensing unit is bent down by the pressurization of a vehicle when the vehicle passes. A housing (2) supports one end and the other end of the sensing unit when the sensing unit is bent by the pressurization of the vehicle. A sensor unit (4) senses the downward movement of the sensing unit in a non-contact manner when the sensing unit enters a sensing region by being bent by the pressurization of the vehicle.
Patent KR-20130113034-A (KR)
Title: Can bus system
Inventor: KWON HAE YUN
IPC: H04L29/02
Filed: 2012-04-05
Abstract: PURPOSE: A bus device for a high speed controller area network (CAN) communication is provided to increase the number and length of a branch line by reducing the branch line influence of a high speed CAN bus. CONSTITUTION: A bus device for high speed CAN communication comprises a branch line (20) connecting a gap between a CAN node (30) and the main line (10) of a high speed CAN bus. A filter circuit (40) is attached to an initial end part of a branch line. The filter circuit comprises an input buffer, an output buffer, and a signal line. The input buffer reflects the CAN signal from a main line or transmits the CAN signal to the CAN node. The output buffer outputs the signal from the CAN node.
Patent KR-20120054580-A (KR)
Title: Apparatus for processing substrate and method thereof
Inventor: HYUN JAE IL
IPC: H01L21/302
Filed: 2012-04-17
Abstract: PURPOSE: A substrate processing apparatus and a method thereof are provided to reduce substrate process time by separately operating each part by dividing a unit which has a slope control function among substrate transfer units. CONSTITUTION: A cleaning process is performed with respect to a substrate in a cleaning process section. The cleaning process section is a section for a process performed in a single chamber. A substrate transfer unit(360) transfers the substrate in a first direction within the cleaning process section. The substrate transfer unit is divided in to two or more parts in the first direction. The divided part changes a slope of the substrate.
Patent KR-20130077745-A (KR)
Inventor: SHIN SUN HWA
IPC: G09G3/20
Filed: 2012-04-20
Abstract: 디스플레이 장치가 개시된다. 본 디스플레이 장치는 서로 다른 컨텐츠를 각각 수신하는 복수의 수신부, 복수의 수신부에서 수신된 컨텐츠들을 각각 처리하여 영상 프레임을 구성하는 복수의 신호 처리부, 복수의 신호 처리부에서 구성된 각 컨텐츠의 영상 프레임을 교번적으로 배치하여 디스플레이하는 디스플레이부, 각 컨텐츠의 디스플레이 타이밍에 따라, 각 컨텐츠에 대응되는 안경 장치를 동기화시키는 동기화 신호를 생성하는 동기화 신호 생성부, 안경 장치에 대응되는 동기화 신호를 전송하는 통신 인터페이스부 및, 타 안경 장치에 대응되는 컨텐츠 확인 명령이 입력되면, 타 안경 장치에 대응되는 컨텐츠 정보를 안경 장치에 대응되는 컨텐츠의 디스플레이 타이밍에 표시하는 제어부를 포함한다.
Patent KR-20130120673-A (KR)
Title: Blast furnace operation method
Inventor: KIM TAE MIN
IPC: C21B5/00
Filed: 2012-04-26
Abstract: The present invention relates to a method for operating a shaft furnace. The method for operating the shaft furnace includes steps for converting heat flow ratio expression, which is expressed with a ratio of thermal capacity of an object and the thermal capacity of gas, into the heat flow ratio expression formed with elements of wind supply conditions; deducting the wind supply condition in a management range of the heat flow ratio for controlling a position of a heat conservation band by applying the converted heat flow ratio expression; and performing a shaft furnace work with the deducted wind supply conditions. The present invention enables the shaft furnace work to be efficiently performed as the wind supply condition in the management rate of the heat flow ratio can be controlled. [Reference numerals] (AA) Oxygen enrichment (Nm^3/hr);(BB) Heat flow rate driving range 0.83<HFR<0.88;(CC) Air flow rate (Nm^3/min)
Patent KR-20130127729-A (KR)
Title: Abutment and crown having ion etching coping section, method for manufacturing of the abutment and crown and method for coupling of abutment and crown using the ion etching
Inventor: BAE JIN WOONG
IPC: A61C5/08
Filed: 2012-05-15
Abstract: The invention relates to an abutment having an ion-etched coping section, a crown-integrated abutment having an ion-etched coping section, a method for manufacturing the abutment and method for combining the abutment. More specifically, the present invention relates to a method for combining an abutment having an ion-etched coping section and a crown, characterized by comprising the steps of: manufacturing a first preliminary block body to form a crown which is an artificial tooth and a second preliminary block body to form an abutment; processing the first preliminary block body to manufacture a crown wherein a joint groove is provided in the inside, and processing the second preliminary block body to manufacture an abutment having a core unit capable of being attached the outer surface of the joint groove and a connecting unit which is provided in the lower end capable of being inserted and installed into the upper part of the implant crown; manufacturing a coping section by ion-etching the outer or inner surface of Zirconia; coupling the coping section to the outer surface of the core section; and attaching and combining the crown with the coping section which is coupled to the outer surface of the core section. [Reference numerals] (AA) Start;(BB) End;(S10) Tooth 3D modeling;(S20) Manufacture a first preliminary block, Manufacture a second preliminary block;(S31) Model a crown;(S32) Manufacture the crown;(S33) Model a support section;(S34) Manufacture a core section and manufacture a connection section;(S35) Manufacture a zirconia block;(S36) Perform a sputtering treatment to the zirconia block and manufacture a zirconia coping section;(S37) Combine a coating section with the outer surface of the core section to manufacture an abutment;(S40) Combine the crown with the abutment
Patent KR-20130128080-A (KR)
Title: Method for removing of copper-ion from solutions containing low concentration copper
Inventor: PARK KYUNG HO
IPC: C22B23/00
Filed: 2012-05-16
Abstract: The present invention relates to a method for removing copper ions, wherein the method includes: a step (a) of selectively absorbing and removing the copper ions from a mixed solution, which contains the copper ions and at least one or two metal ions selected from nickel ions, cobalt ions, and iron ions, using an ion exchange resin which is a chelate resin having an iminodiacetic acid functional group; and a step (b) of recovering copper by detaching the copper from the ion exchange resin in which the copper ions are absorbed. The present invention also relates to the copper which is detached and recovered from the ion exchange resin, which the copper ions are absorbed in, by the method using an eluent containing 2 to 12 vol% of sulfuric acid. [Reference numerals] (AA) Solution including nickel, cobalt, iron, and low concentration copper;(BB) Sulfuric acid/sodium hydroxide;(CC) pH adjustment;(DD) Copper attachment;(EE) Resin/solution separation;(FF) Ion exchange resin;(GG) Solution;(HH) Eluant;(II) Detachment;(JJ) Nickel/cobalt recovery process;(KK) Resin/eluant separation;(LL) Ion exchange resin;(MM) Copper-containing solution;(NN) Copper recovery process
Patent KR-20120129829-A (KR)
Title: Method for removing nitrogen in waste water
IPC: C02F3/12
Filed: 2012-05-18
Abstract: PURPOSE: A removal method of nitrogen from sewage and wastewater is provided to optimize a partial nitrification process and to remove nitrogen from wastewater of low nitrogen concentration. CONSTITUTION: A removal method of nitrogen from sewage and wastewater includes the following steps: sewage and wastewater are introduced(S1); a nitrate nitrogen accumulating process is implemented to heterotrophic denitrify and partial nitrify the sewage and the wastewater(S2); a sulfur denitrification process is implemented to autotrophic denitrify the sewage and the wastewater; and nitrogen removed water is drained. [Reference numerals] (AA) Gas analysis; (BB) S^0 particles
Patent KR-20130130515-A (KR)
Title: Echant for silver pattern
Inventor: PARK JIN CHUL
IPC: C09K13/06
Filed: 2012-05-22
Abstract: The present invention relates to an etchant used in wet-etching a metal film in a manufacturing process of a flat panel display (FPD) and, more specifically, to an etchant related to a single film consisting of Ag or an Ag alloy; and a multilayer consisting of an alloy film of Ag and a heterogeneous metal, Ag and a transparent conductive metal such as indium tin oxide (ITO) and indium zinc oxide (IZO), especially to a triple film of transparent electrode/Ag-palladium alloy film/transparent electrode.
Patent KR-20130134165-A (KR)
Title: Photographing apparatus, method for controlling the same, and computer-readable recording medium
Inventor: JUNG JAE HYO
IPC: H04N5/238
Filed: 2012-05-30
Abstract: The present invention provides a method for controlling an imaging system comprising the steps of: comparing the brightness of a preview image and a captured image; and revising the shutter driving properties according to the differences of the preview image and the captured image. [Reference numerals] (610) Brightness comparing unit;(620) Shutter correcting unit;(AA) Preview image;(BB) Captured image
Patent KR-20120138658-A (KR)
Title: Clinical examination analyzing device and cleaning method for the clinical examination analyzing device
Inventor: NAKAYAMA YOSHIYUKI
IPC: G01N35/10
Filed: 2012-06-11
Abstract: PURPOSE: An analysis device for clinical examination and a washing method for the same are provided to effectively wash the washing nozzle of a reactor washing device by including a nozzle washing mode. CONSTITUTION: An analysis device(1) for clinical examination includes a sample turntable(4), a reagent turntable(8), a reaction turntable(12), a sample pipette, a reagent pipette(17), a reactor washing unit(23), and a controlling unit. A sample vessel is arranged on the sample turntable. A reagent vessel(7) is arranged on the reagent turntable. A reactor(11) is arranged on the reaction turntable. The sample pipette discharges a sample to the reactor of the reaction turntable. The reagent pipette absorbs reagent from the reagent vessel and discharges the reagent to the reactor on the reaction turntable. The reactor washing unit includes a plurality of washing nozzles.
Patent KR-20130138608-A (KR)
Title: Site-specific antibody-cytotoxin conjugate and use thereof
Inventor: SONG DAE HAE
IPC: C07K19/00
Filed: 2012-06-11
Abstract: The present invention relates to an antibody-cytotoxin conjugate in which a site-specific cytotoxin is conjugated at an N-terminal amino group with respect to a cancer cell surface antigen and a preparation method thereof. In addition, the present invention relates to a composition for cancer diagnosis or treatment using the antibody-cytotoxin conjugate to diagnose or treat diseases under in vivo and in vitro conditions. Using the composition for cancer treatment including the antibody-cytotoxin conjugate enables specific targeting and relieves increased antibody-dependent cytotoxicity and side effects due to strong cytotoxicity, compared to independent treatments of antibody or cytotoxin. Furthermore, since the conjugate maintains homogeneity, the heterogeneity of the conventional antibody-cytotoxin conjugate can be overcome, and the present invention can be applied for developing a more effective antibody-cytotoxin conjugate since the cytotoxin is combined to the alpha-amine and N-terminal of the antibody using antibody that is not genetically manipulated.