baber/WOPTO huggingface dataset:
Patent CA-2187200-A1 (CA)
Title: Nadh oxidase as a target in diagnosis and therapy
Inventor: MORRE D JAMES
IPC: A61K31/165
Filed: 1995-04-04
Abstract: Plasma membrane NADH oxidase is shown to be a target for a variety of uses in diagnotis and therapy. Particularly, the NADH oxidase associated with neoplastic cells is immunologically and biologically different from NADH oxidase associated with normal cells. Thus, the presence of tumor cells in patients can be monitored by monitoring serum or biopsy samples for the presence of disease associated NADH oxidase. By employing NADH oxidase as a target for inhibitors, tumor cells, virally infected cells and cells having multiple drug resistance may be specifically affected, while not affecting normal cells. Specific inhibitors having increased activity for disease associated NADH oxidase as compared to normal NADH oxidase are provided. The use of the NADH oxidase associated with tumor cells provides opportunities for assays for screening drugs that are specific for neoplastic cells and can serve as anticancer drugs or growth inhibitors.
Patent CA-2189705-A1 (CA)
Title: Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haematopoetic cell system
Inventor: PERGANDE GABRIELA
IPC: A61P7/00
Filed: 1996-11-06
Abstract: The invention relates to the use of flupirtine or its salts as drugs in the prophylaxis and therapy of diseases associated with an impairment of the haematopoetic cell system, for example lymphocytes. Especially important in this respect is the treatment of HIV infected patients/AIDS patients.
Patent CA-2194740-A1 (CA)
Inventor: WOOLSEY MICHAEL E
IPC: F24F13/068
Filed: 1997-01-09
Abstract: An induction diffuser (100), radial flow diffuser (130), linear diffuser (150) and supply or return grille (170) are disclosed which use a fabric face (102, 132, 152, 172) to form the exposed portion thereof.  The fabric face is preferably made of fiberglass or Kevlar coated with teflon.  The use of the fabric face increases reflectivity of incident light, reduces sound levels, provides a durable and easily cleanable surface and provides other significant benefits.
Patent CA-2194854-A1 (CA)
Title: Casing Joint Detector
Inventor: PRICE TIMOTHY M
IPC: E21B47/09
Filed: 1997-01-10
Abstract: A  borehole  instrument  that  detects  the  joints  of successive axial lengths of magnetic material enclosing a borehole while traveling along the inside of the enclosure by detecting anomalous magnetic fields indicative of the enclosure's joints.  One embodiment of the invention is to measure the distance the instrument travels along the inside of the borehole enclosed or cased with a magnetic material by traversing along a borehole while measuring one or more magnetic field parameters interior to the enclosure of the magnetic casing, processing the measured parameters to detect anomalous static magnetic fields that are  indicative of the  joints of  the casing lengths; determining the distance traveled along the borehole at each joint by summing the known lengths of the casing; correlating the discrete distances computed at the casing joints with a primary distance measuring device that is higher resolution but lower in accuracy, and calibrating the primary device using the discrete distances known at the casing joints.  Further embodiments include detecting pre-magnetized enclosures or implanted magnetic markers.
Patent CA-2195288-A1 (CA)
Title: Method for identifying and quantifying polymers utilizing immunoassay techniques
Inventor: KELLER LORRAINE HOLOWACH
IPC: G01N33/18
Filed: 1997-01-16
Abstract: Disclosed is a method for quantitatively identifying polymers in an aqueous system using immunoassay techniques, wherein at least a portion of the polymers contain a detectable terminus. This is particularly useful in water treatment systems. Also disclosed are new hybridoma cell lines which express MAbs which specifically recognize such a detectable terminus.
Patent CA-2198127-A1 (CA)
Inventor: DANIEL SEAN C
IPC: A61B17/00
Filed: 1995-08-07
Abstract: L'invention se rapporte à un système et à un procédé de manipulation d'une structure tissulaire dans une cavité du corps. Selon un mode préféré de réalisation, l'invention concerne un système et un procédé permettant d'écarter des bords de la paroi du coeur et de les maintenir écartés afin de faciliter l'accès au coeur au cours d'une opération du coeur. Ce système comprend un élément (500) de soutien des tissus, que l'on positionne à travers un premier passage intercostal et percutané dans la cage thoracique. Cet élément comporte une surface de contact (502) configurée pour soutenir une partie de la paroi du coeur. Un rétracteur (40a) comprend une tige (400) présentant une extrémité proximale, une extrémité distale configurée pour être introduite par un second passage percutané, dont le diamètre est inférieur à la largeur et à la longueur de ladite surface de contact. Un crochet (428) est accouplé coulissant à l'extrémité distale de la tige afin de retenir de manière libérable l'élément de soutien des tissus de sorte que la surface de contact soit disposée transversalement par rapport à l'axe longitudinal de la tige. Une telle configuration permet d'introduire la tige et l'élément de soutien des tissus à travers deux passages percutanés séparés, après quoi ils sont accouplés à l'intérieur de la cage thoracique afin d'écarter les bords de la paroi du coeur.
Patent CA-2200150-A1 (CA)
Inventor: VENEKAMP JOE
IPC: A41D3/00
Filed: 1997-03-17
Abstract: The modular outer garment for fishing of the present invention has an opposed front and back flexible support members having front and back securement points, the front and back flexible support members releasably securable to the chest and back respectively of the torso of a user, releasable securing means fastened to, and extending between, the front and back support members for snug releasable securement of the support members to the torso, a front compartment fastened to the front support members, the front compartment having a fold-down table foldably storable in the front compartment when in a raised position, and downwardly foldable about a hinge into a lowered generally horizontal position perpendicular to the front compartment.
Patent CA-2203028-A1 (CA)
Inventor: BOURRET GERARD
IPC: H04B10/17
Filed: 1997-04-17
Abstract: Dispositif à deux amplificateurs optiques (13, 14) dont chacun comprend une source de pompage (35, 36), un milieu actif (15, 15 1) tel qu'une fibre optique, et un moyen pour récupérer l'énergie de pompage non utilisée dans le milieu actif afin de la réinjecter dans l'autre amplificateur (14, 13). Le moyen de récupération (20, 20 1, 30, 31) est tel que, dans chaque amplificateur, la réinjection s'effectue en sens contraire du sens d'injection de l'énergie principale de la pompe. Chaque amplificateur comporte, par exemple, une borne (22, 22 1) de récupération qui constitue à la fois une sortie pour l'énergie de pompage non utilisée et une entrée pour la réinjection de l'énergie de pompage récupérée dans l'autre amplificateur. Un simple conducteur (30) effectue une liaison optique entre les bornes (22, 22 1) de récupération des deux amplificateurs (13, 14). Le dispositif est utilisable dans un répéteur pour transmission de signaux optiques à distance, notamment par voie sous-marine.
Patent CA-2207019-A1 (CA)
Title: Dendritic, nitrogen-containing organic compounds containing planar-chiral or axial-chiral end groups, and the preparation and use thereof
Inventor: VOEGTLE FRITZ
IPC: C08G73/02
Filed: 1997-05-23
Abstract: The present invention relates to dendritic, nitrogen-containing organic compounds containing at least 4 planar-chiral or axial-chiral groups, where these planar-chiral or axial-chiral groups are linked as Schiff's bases to the primary amino groups of compounds of the formula (I) (R1R1)N-X-N(R1R1)      (I) where R1  is (R2R2)N-(CH2)2- or (R2R2)N-(CH2)3-, R2  is hydrogen or (R3R3)N-CH2)2- or (R3R3)N-(CH2)3-, R3  is hydrogen or (R4R4)N-(CH2)2- or (R4R4)N-(CH2)3-, R4  is hydrogen or (R5R5)-N-(CH2)2- or (R5R5)N-(CH2)3-, R5  is hydrogen or (R6R6)N-(CH2)2- or (R6R6)N-(CH2)3-and R6  is hydrogen, X   is an aliphatic and/or aromatic group, which may contain heteroatoms, which are suitable as catalysts for asymmetrical homogeneous catalysis.
Patent CA-2209303-A1 (CA)
Title: Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists
Inventor: CHANDRARATNA ROSHANTHA A
IPC: A61K31/19
Filed: 1996-01-31
Abstract: Proliferation of retinal pigment epithelium following surgery or trauma or resulting in ocular diseases associated with choroidal neovascularization, such as age related macular degeneration and histoplasmosis syndrome, is prevented by contacting retinal pigment epithelium cells with a therapeutic amount of a retinoic acid receptor (RAR) agonist, preferably one with specific activity for retinoic acid receptors. Preferably the RAR agonist is also a potent antagonist of AP1-dependent gene expression. Alternatively, the proliferation of retinal pigment epithelium is ameliorated with a therapeutic amount of an AP-1 antagonist, alone or in combination with an RAR agonist. The drug can be administered by bolus injection into the vitreous cavity using a dosage from about 50 to 150 µg, or by slow release from liposomes or an oil tamponade injected into the vitreous cavity. Formulations for preventing proliferation of retinal pigment epithelium are also provided.
Patent CA-2209511-A1 (CA)
Inventor: BOUVIER MICHEL
IPC: G01N33/94
Filed: 1997-06-30
Abstract: This invention is a new method of assaying compounds that modulate the activity of G protein-coupled receptors based on measurement of changes in the relative proportions of monomeric to multimeric receptor polypeptides. More specifically, techniques are described herein which permit the prediction of the pharmacological efficacy of drug candidates based solely on the ability of the candidate compounds to alter the ratio of receptor monomer to homo-oligomeric forms of the receptor. This method provides a novel means of assaying compounds as potential therapeutic drugs at G protein-coupled receptors which is greatly simplified and more generally applicable than existing methods.
Patent CA-2215242-A1 (CA)
IPC: F16K31/08
Filed: 1997-09-11
Abstract: An actuator for opening and closing a valve with less resistance. The actuator includes a rotor, a stator, a valve and a shaft. The shaft having a first and second end, and an axis extending longitudinally therethrough. The stator, having an electromagnet mounted thereon, and circumferentially mounted around the shaft that extends therethrough. The rotor, fixedly mounted circumferentially around the first end, and having a permanent magnet mounted adjacent to the electromagnet and spaced a first distance therefrom. The valve including a rotary valve and valve seat. The rotary valve, mounted circumferentially around and near the second end, having a valve opening therein. The valve seat, mounted adjacent the rotary valve, having a seat valve opening therein, and fixedly attached to the stator. There actuator is designed for axially moving the rotor from the first distance to a second greater distance from the stator and thereby moving the rotary valve further away from the valve seat, and then axially rotate the shaft to a second position that aligned the seat valve opening and the valve opening, and then moving the rotor from the second distance back to the first lesser distance.
Patent CA-2215462-A1 (CA)
Inventor: PICKMAN E STEVEN
IPC: B65D50/00
Filed: 1997-09-15
Abstract: A child resistant container apparatus includes a container for containing a substance and having an opening; a first inner cap member for removably covering the opening; first threads for rotationally engaging the first cap with the opening in a first direction of rotation; a second outer cap member for removably covering the first cap; and second threads for rotationally engaging the second cap with the first cap in a second direction of rotation, wherein the first direction of rotation is opposite to the second direction of rotation.  The first and second direction are selected to provide opening of the container through rotation in an unexpected direction.
Patent CA-2217463-A1 (CA)
Inventor: OLLAT HELENE
IPC: A61P25/16
Filed: 1997-10-02
Abstract: Utilisation de la sulbutiamine pour l'obtention de compositions pharmaceutiques utiles dans le traitement de certains troubles psychomoteurs et psycho-intellectuels observés c hez les malades parkinsoniens, schizophrènes déficitaires, alcooliques, déprimés majeurs et dysthymiques.
Patent CA-2219145-A1 (CA)
Title: A method and apparatus for arteriotomy closure
Inventor: COURY WILLIAM S
IPC: A61F2/06
Filed: 1995-11-28
Abstract: The present invention provides an apparatus (10) and a method for quickly and effectively sealing an arteriotomy site in a patient. In particular, the invention provides an apparatus and method for sealing an arteriotomy site which can be performed by a single operator. The arteriotomy can be sealed by delivery of a suitable sealant (36) such as a patient specific autologous fibrin glue to a debrided, synthesized area (35) adjacent to the extravascular opening (4) of the arteriotomy. Alternatively, synthetically produced fibrin glue or other sealants can be utilized in a method of sealing an arteriotomy site.
Patent CA-2219909-A1 (CA)
Title: Processes and compositions for remineralization and prevention of demineralization of dental enamel
Inventor: WINSTON ANTHONY E
IPC: A61K8/21
Filed: 1996-06-05
Abstract: The present invention relates to the problems of remineralization, without demineralization of dental enamel by applying to the teeth a composition which is present in two phases which do not react with one another until introduced into the oral cavity. One phase contains at least one water-soluble calcium compound and the other contains at least one water-soluble inorganic phosphate and at least one water-soluble fluorine compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent reaction causes rehardening of demineralized areas in the dental enamel.
Patent CA-2220364-A1 (CA)
Inventor: DE HAAS JACOBUS JOHANNES
IPC: G01R31/36
Filed: 1996-05-08
Abstract: The invention relates to a method for sorting batteries (10), with batteries being separated on the basis of a measured electrical property which is characteristic of their composition. The electric property of the battery is according to the invention determined by applying to the battery (10) a varying electrical voltage and measuring the resulting current through the battery. The varying electrical voltage advantageously consists of a first pulse and a second pulse which have opposite polarities, and which may both be generated by the discharge of a capacitor (2). In addition, a second property may be determined, e.g., the shape or colour of the battery. With such method, a very effective separation between, e.g., nickel-cadmium, alkaline, lithium, and other batteries may be obtained. The invention further relates to a device (1) for determining electrical properties of batteries.
Patent CA-2221805-A1 (CA)
Title: Bidirectional steerable catheter with deflectable distal tip
Inventor: KOBLISH JOSEF V
IPC: A61M25/01
Filed: 1996-05-22
Abstract: A bidirectional catheter (10) with a deflectable tip (14) at a distal end includes a handle (12) at a proximal end (15) and a tubular member (11) extending between the tip and the handle. The handle includes a first piston member (16) slidably mounted in a handle base (20) with proximal ends of steering wires (22, 23) secured in the handle. The steering wires extend through the tubular member with respective distal ends thereof secured to circumferentially spaced portions (24, 25) of the distal end tip. Axial displacement of the piston member in a second direction conversely urges deflection of the distal end tip in a second direction by tensioning the other wire relative to the first wire. The piston member can include another piston member (17) slidable in the first piston member with the proximal ends of the steering wires secured in the first memtioned piston member and the handle member, respectively, and with the other piston member supporting a proximal end of the tubular member.
Patent CA-2222011-A1 (CA)
Inventor: HERZ JOSEF PAUL
IPC: A63B67/14
Filed: 1996-05-22
Abstract: Amélioration d'une pierre de curling connue sous le numéro de brevet autrichien 354,921.  Une coquille de support (2), présentant une ou plusieurs ouvertures (6) pour rendre le mécanisme de freinage accessible, est placée en appui entre le manche (1) et le boîtier (3), la coquille présentant dans sa surface supérieure un trou central.  Selon un modèle préféré, la console (9) du mécanisme de freinage s'avère un support essentiellement élastique de section transversale étoilée et pourvu, de préférence, de trois à six bras (11) présentant des fentes radiales décroissantes (18, 19) servant à recevoir les supports de surface de frein (15).
Patent CA-2222152-A1 (CA)
Inventor: NESTEROVA AINAIDA V
IPC: G02F1/01
Filed: 1997-07-01
Abstract: An optical fiber switch in accordance with the present invention includes an optical fiber, a gate signal generating system, and a coupling system. The optical fiber has a birefringence between 10-5 and 10-6 and an effective area of at least 40 square microns. The generating system generates a gating signal having a power level which induces non-linear birefringence in the optical fiber causing an input signal in the optical fiber to switch polarization modes. The coupling system couples the input signal and the gating signal into the optical fiber. The optical fiber in the optical fiber switch is designed to minimize non-linear effects which would degrade an input signal in the optical fiber switch. In particular, the optical fiber switch is designed to reduce the amount of power required by the gating signal to switch the input signal in the optical fiber, thus reducing the possibility of fiber fuse and the generation of higher order solitons through Raman effects.
Patent CA-2223694-A1 (CA)
Title: Isolated nucleic acid molecules, peptides which form complexes with mhc molecule hla-a2 and uses thereof
Inventor: LUCAS SOPHIE
IPC: A61K48/00
Filed: 1996-05-07
Abstract: New tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as NAG tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as NAG coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigen precursor molecules are discribed.
Patent CA-2225722-A1 (CA)
Title: Systeme pour ameliorer la visibilite d'un objet en television, lors de la retransmission d'un evenement sportif
Inventor: GEPNER JERRY NEIL
IPC: H04N5/262
Filed: 1996-06-28
Abstract: Un système pour améliorer la visibilité, à la télévision, d'un objet, lors de la retransmission d'un événement sportif, comprend un détecteur, qui détermine l'emplacement de l'objet. A partir de l'emplacement de l'objet et du champ de vision d'une caméra, un processeur détermine la position de l'objet dans l'image vidéo. Une fois que l'on sait où l'objet est positionné dans l'image, le signal de télévision peut être modifié ou augmenté pour améliorer la visibilité de l'objet.
Patent CA-2226368-A1 (CA)
Title: Silyl terminated sulfopoly(ester-urethane) pavement marking compositions
Inventor: PURGETT MARK D
IPC: E01F9/04
Filed: 1996-06-25
Abstract: A pavement marking composition comprises a sulfopoly(ester-urethane) polymer which comprises in its backbone at least one non-terminal arylene or alkylene group comprising a pendant sulfonic acid group or salt thereof, the polymer of said pavement marking composition being terminated by at least one hydrolysable silyl group. A method of making the composition is disclosed. The pavement marking composition can further comprise at least one of pigments, optical elements, fillers, or other adjuvants. Particularly desirable adjuvants include optical elements, particularly retroreflective elements, skid-resistant particles, and pigments.
Patent CA-2226823-A1 (CA)
Title: Leaf spring stabiliser
Inventor: LAMBERTI ANTONETTE IRENE
IPC: F16F1/22
Filed: 1998-01-09
Abstract: A vehicle spring stabiliser has a leaf spring with a connector pivotally secured to each and eye thereof, the connector in the form of a rigid yoke to embrace a vehicle spring assembly and having anti-friction means in the form of a sleeve on a spacer mounted on a bolt connecting the arms of the yoke.
Patent CA-2227730-A1 (CA)
Inventor: LORCH ERHARD
IPC: G03F3/00
Filed: 1996-06-26
Abstract: A process is proposed for printing an object using chromatic components from a three- or four-colour set of a printing pattern. The neutral parts of the chromatic components of the three-colour set are reduced to produce a neutral component and correspondingly modified chromatic components. The object is printed using the modified chromatic components and a special colour based on the neutral component.
Patent CA-2230908-A1 (CA)
Title: Longitudinal nmr well logging apparatus and method
Inventor: TAICHER GERSH ZVI
IPC: G01V3/32
Filed: 1998-02-26
Abstract: The invention is a nuclear magnetic resonance sensing apparatus comprising a magnet for inducing a static magnetic field in a region containing materials to be analyzed. The static magnetic field is polarized generally along the axis of the apparatus. The static magnetic field has a predetermined maximum longitudinal and maximum radial amplitude gradient. The apparatus includes a transmitter antenna for generating a radio frequency magnetic field in the region for exciting nuclei of the materials to be analyzed by conducting a radio frequency current through the transmitter antenna. The apparatus includes a receiving antenna for detecting a nuclear magnetic resonance signal from the excited nuclei. In a particular embodiment, the transmitter antenna and receiver antenna consist of coil pairs, each coil in a pair separated from the other by 90 degrees, to generate a circularly polarized RF magnetic field and to perform quadrature detection of the NMR signals.
Patent CA-2231009-A1 (CA)
Title: Coaxial connector for switching antennas
Inventor: MIYAKE YUKINORI
IPC: H01R13/703
Filed: 1998-03-04
Abstract: A flexible detecting terminal 6 is provided within an inside connector 1 in the vicinity of the cylindrical outer conductor 5 which surrounds a central conductor 4. An outside connector 52 has a central conductor 52A for connection with the central conductor 4 and a conductive shell 52B fitted over the cylindrical outer conductor 5. A contact section 6B is provided on the detecting terminal 6 such that when the connectors 1 and 52 are not connected to each other, it is spaced from the cylindrical outer conductor 5 but when the connectors 1 and 52 are connected to each other, it is brought into resilient contact with the cylindrical outer conductor 5.