baber/WOPTO huggingface dataset:
Patent AT-E319691-T1 (AT)
Inventor: BLACK LAWRENCE A
IPC: A61K31/50
Filed: 1998-08-20
Granted: 2006-03-15
Abstract: The present invention describes pyridazinone compounds which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important "housekeeping" enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).
Patent AT-E366130-T1 (AT)
Inventor: WAX MICHAEL
IPC: A63B21/008
Filed: 1998-11-05
Granted: 2007-07-15
Abstract: A training device is disclosed for exercising the pubococcygeal or pelvic floor muscles, for example, in the treatment of incontinence. The device includes a cylindrical, deformable probe (50) for insertion into the vagina or rectum of a user. The probe is connected to a pressure transducer (110), which detects the pressure applied to the probe by contraction of the pelvic floor muscles, and displays a pressure indicator (76). The pressure indicator( 76) may take the form of a series of nested figures (146), such as curves or concentric semi-circles, that incrementally converge toward a common point as pressure on the probe increases. The training unit guides the user through an exercise routing. The training unit can include a controller (168) that tracks the timing of exercises performed by the user, guides the user through alternating cycles of muscular contraction, and relaxation.
Patent AT-E258520-T1 (AT)
Inventor: NACE JOHN E
IPC: B60Q1/30
Filed: 1999-07-06
Granted: 2004-02-15
Abstract: A motorcycle tail light (20) is described which comprises a housing (57), a lens (62) mounted to the housing (57) and a light source assembly (52) between the lens (62) and the housing (57). The light source assembly (52) comprises a frame (92) having an aperture, a light source (96) mounted within the aperture, and an elastomer member (94) positioned in the aperture and compressed between the light source (96) and the frame (92). <IMAGE>A motorcycle tail light (20) is described which comprises a housing (57), a lens (62) mounted to the housing (57) and a light source assembly (52) between the lens (62) and the housing (57). The light source assembly (52) comprises a frame (92) having an aperture, a light source (96) mounted within the aperture, and an elastomer member (94) positioned in the aperture and compressed between the light source (96) and the frame (92). <IMAGE>
Patent AT-E282373-T1 (AT)
Inventor: BOUMA-DE VRIJER RICKIE
IPC: A61F2/958
Filed: 1999-07-26
Granted: 2004-12-15
Abstract: The present invention relates to a balloon catheter for positioning a stent, including a tubular basic body with a proximal end and a distal end, and at least one lumen extending in between, a balloon close to the distal end which is connected to the lumen, and a stent crimped around the balloon, wherein a filling body of elastic material is arranged inside the balloon and has a size corresponding to at least the dimensions of the stent in compressed state, where the filling body is compressed by the stent in the compressed state. <IMAGE>
Patent AT-E292797-T1 (AT)
Inventor: HINCHLIFFE MALCOLM GEOFFREY
IPC: D06H3/00
Filed: 1999-08-16
Granted: 2005-04-15
Abstract: An instrument (10) is provided with several sensing elements (14, 15, 16) to enable several parameters of a processed yarn (12) to be measured or determined. In order to minimise the total sensing element/guide contact with the yarn (12) within the complete process threadline, the yarn (12) is guided through the instrument (10) by contact only with the inlet and outlet guiding elements (13, 17) of the instrument (10) and contact operative sensing elements (20). One particular instrument (10) consists, in succession, of an interlace sensing device (14), a tension sensing device (15) and an oil content sensing device (16). The electrical resistance of the yarn (12) is measured between two pins (20, 17) of the oil content sensing device (16) and in this case, the first pin (20) is also a tension sensing pin (20) of the instrument (10), and the second pin (17) of the oil content sensing device (16) is also the outlet guide (17) of the instrument (10). <IMAGE>
Patent AT-E221948-T1 (AT)
Inventor: BRIOSCHI EDOARDO
IPC: E05D3/06
Filed: 1999-04-21
Granted: 2002-08-15
Abstract: The door structure has hinges (1) for applying the door to a wall of a piece of furniture. Each hinge has a support (6) formed in a mutually matching manner so that the former are slidably guided by the latter. Fixing screws fit into threaded holes passing through the respective supports, so that when they are tightened they act against the inner wall of a section and force the supports against it to lock them in the desired position.
Patent AT-E209608-T1 (AT)
Inventor: LANGELIN HENRI RENE
IPC: C01F11/18
Filed: 1999-05-27
Granted: 2001-12-15
Abstract: The invention concerns an aqueous suspension of precipitated calcium carbonate particles, said suspension having a pH stabilised at a value less than 9, said calcium carbonate particles containing an agent for obtaining a positive zeta potential of the calcium carbonate particles, the agent for obtaining a positive zeta potential being a substance causing Ca<++> ions to dissolve.
Patent AT-E247988-T1 (AT)
Inventor: CORDICK RAE ANNE
IPC: A61L9/01
Filed: 1999-07-13
Granted: 2003-09-15
Abstract: The present invention provides in one aspect for a method for controlling odor associated with spills of organic material which can cause odors on carpets. The method comprises applying to the carpet a preparation of dormant bacteria, which when activated are effective to control odors. The dormant bacterial preparation is allowed to become associated with the carpet, such that when the carpet is exposed to organic material which can cause odors, the bacteria are capable of becoming active and digesting the organic material. The formulation may contain other agents such as odor neutralizing or masking agents, enzymes, foaming or anti-foaming agents.
Patent AT-E463571-T1 (AT)
Inventor: KENNEDY GIULIA
IPC: C07K14/47
Filed: 1999-06-22
Granted: 2010-04-15
Abstract: The present invention provides the art with the DNA coding sequences of polynucleotides that are up-or-down-regulated in cancer and dysplasia. These polynucleotides and encoded proteins or polypeptides can be used in the diagnosis or identification of cancer and dysplasia. Inhibitors of the up-regulated polynucleotides and proteins can decrease the abnormality of cancer and dysplasia. Enhancing the expression of down-regulated polynucleotides or introducing down-regulated proteins to cells can decrease the growth and/or abnormal characteristics of cancer and dysplasia.
Patent AT-E227989-T1 (AT)
Inventor: GERMANN PAUL-GEORG
IPC: C07D333/36
Filed: 1999-06-19
Granted: 2002-12-15
Abstract: Novel compositions for the treatment of IRDS and ARDS are indicated which contain a compound of formula (I), in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound and lung surfactant.
Patent AT-E345785-T1 (AT)
Inventor: MUNDY GREGORY R
IPC: A61K45/00
Filed: 1999-07-09
Granted: 2006-12-15
Abstract: This inventions relates to compounds that inhibit the activity of the proteasome and both promotes hair growth and stimulates the production of hair follicles. The compounds provided herein are thus useful in stimulating hair growth, including hair density, in subject where this is desirable.
Patent AT-E279836-T1 (AT)
Inventor: ELLIS MICHAEL D
IPC: H04N21/431
Filed: 1999-07-16
Granted: 2004-10-15
Abstract: An interactive television program guide with remote access is provided. The interactive television program guide is implemented on interactive television program guide equipment. A remote program guide access device is connected to the interactive television program guide equipment by a remote access link to provide a user with remote access to program guide functions.
Patent AT-E453667-T1 (AT)
Inventor: OKU NAOTO
IPC: A61K38/00
Filed: 1999-10-15
Granted: 2010-01-15
Abstract: Angiogenesis-specific peptides which home selectively to neovascular tissues and comprise one of the peptides having the amino acid sequences shown in SEQ ID NOS: 1 to 17 and dendrimers thereof. These peptides are applicable to DDS preparations whereby drugs can be transported selectively to target cancer tissues and are useful as diagnostics for cancer, remedies for cancer, etc. which contribute to the improvement in the therapeutic effects on cancer.
Patent AT-E304702-T1 (AT)
Inventor: AGNER ERIK
IPC: G01N30/16
Filed: 1999-10-20
Granted: 2005-09-15
Abstract: A method of sample displacement chromatography separation which comprises applying a multicomponent sample to one end of a chromatography bed comprising stationary phase material having affinity for components of the sample, causing components of the sample to become distributed along the chromatography bed by passage over the bed of a non-eluting mobile solvent phase, and recovering a desired component of the sample from at lest a portion of the chromatography bed, in which the sample components are applied to the chromatography bed in a non-homogeneous manner such that the concentration of at least one component with relatively low affinity for the stationary phase material is enhanced during an earlier part of sample application and/or the concentration of at least one component with relatively high affinity for the stationary phase material is enhanced during a later part of sample application.
Patent AT-E261087-T1 (AT)
Inventor: LEE ROBERT MICHAEL
IPC: F17C5/06
Filed: 1999-10-25
Granted: 2004-03-15
Abstract: Methods and apparatus for filling containers with a gas or gas mixture under pressure are disclosed. The apparatus comprises a fixed volume vessel for containing the gas at a pressure P1, a line extending from the fixed volume vessel to a buffer volume vessel which has a capacity greater than the volume of the container to be filled, a pressure controller for controlling the pressure of the gas in the line so that the gas reaches the buffer volume vessel at a pressure P2 which is less than P1, a further line extending from the buffer volume vessel to at least one filling nozzle, and a valve located in the further line for controlling the flow of gas from the buffer volume vessel to the gas capsule to be filled.
Patent AT-E254741-T1 (AT)
Inventor: HULLDIN ROLAND
IPC: H05B3/20
Filed: 1999-09-09
Granted: 2003-12-15
Abstract: The invention relates to a heating cable mat (1) comprising a net-shaped supporting element (2) and a heating cable (4) which is arranged on the supporting element. The surface (3) of the supporting element is adhesive, and the heating cable (4) is arranged in abutment against the supporting element (2). To further fix the heating cable (4), a second net-shaped supporting element (10) is arranged adjacent to the heating cable mat so that the heating cable (4) is located between the two supporting elements (2, 10).
Patent DE-03003341-T1 (DE)
Title: Keramisches Abziehbild
Inventor: GEDDES PAMELA A
IPC: C04B41/81
Filed: 2003-02-13
Abstract: Keramische Abziehbildanordnung, welche ein Substrat, eine mit dem genannten Substrat verbundene Klebstoffschicht und ein mit der genannten Klebstoffschicht verbundenes keramisches Abziehbild umfasst, wobei:  a) das genannte Substrat ausgewählt wird aus der Gruppe, welche aus Glassubstrat, Keramiksubstrat und Glas-Keramik-Substrat besteht;  b) die genannte Klebstoffschicht aus druckempfindlichem Klebstoff besteht, eine Stärke von weniger als ungefähr 100 Mikrometer aufweist und zu mindestens etwa 95 Prozent aus kohlenstoffhaltigem Material besteht;  c) das genannte keramische Abziehbild aus einem flexiblen Substrat, einer Ablöseschicht für das Abziehbild, einer übertragbaren Abdeckschicht und einer Bildschicht besteht, wobei:  1. sich die genannte Ablöseschicht für das Abziehbild zwischen dem genannten flexiblen Substrat und der übertragbaren Abdeckschicht befindet,  2. die genannte übertragbare Abdeckschicht zu mindestens 25 Gewichtsprozent aus thermoplastischem Material mit einer Bruchdehnung größer als etwa 2 Prozent besteht,  3. die genannte Bildschicht aus Teilchen besteht, die aus der Gruppe ausgewählt werden, welche aus Trübungsmittelteilchen, Farbgebungsteilchen...
Patent DE-843757-T1 (DE)
Inventor: ROUNSAVILLE JEFFREY
IPC: D21C11/06
Filed: 1996-08-06
Abstract: A method for reprocessing an ozone-containing gas present in a pulp bleaching plant comprising the steps of supplying the ozone-containing gas to a scrubber and reducing the ozone concentration of the gas as the gas flows through the scrubber. The step of reducing comprises the steps of supplying an alkaline medium to the scrubber and flowing the ozone-containing gas in countercurrent relationship with the alkaline medium within the scrubber so as to provide intimate contact between the ozone-containing gas and the alkaline medium, thereby converting the ozone-containing gas into a substantially ozone-free gas. The alkaline medium may comprise one of the following: a sodium hydroxide solution; white liquor; post oxygen stage filtrate; weak black liquor; or filtrate from an Eo stage of the pulp bleaching plant. The method further comprises the step of separately discharging the ozone-containing gas and the alkaline medium from the scrubber. The ozone-containing gas may comprise an off-gas, which has been partially reacted with a pulp within a pulp bleaching stage or alternatively may comprise fresh bleaching gas, having an ozone concentration ranging from about 6 % to about 14 % by weight within a carrier gas, with the fresh bleaching gas being supplied directly from an ozone generator to the scrubber.
Patent DE-97905729-T1 (DE)
Inventor: PARNET PATRICIA
IPC: A61K38/00
Filed: 1997-02-06
Abstract: 2F1 polypeptides are provided, along with DNA sequences, expression vectors and transformed host cells useful in producing the polypeptides. Soluble 2F1 polypeptides find use in inhibiting prostaglandin synthesis and treating inflammation.
Patent ES-2188433-T1 (ES)
Title: Procedimiento para la preparacion de sales calcicas de acidos grasos para gliceridos elevados en contenidos de aceites.
Inventor: LUCHINI NESTOR DANIEL
IPC: A23K1/16
Filed: 2002-05-03
Abstract: Un procedimiento para la preparación de sales cálcicas de ácidos grasos que comprende; (a) suministrar una materia prima de ácido graso que tenga un contenido en glicéridos de aproximadamente entre 30 % y aproximadamente 60 % en peso; (b) añadir a dicha materia prima desde aproximadamente 2 a aproximadamente 3 equivalentes de óxido de calcio en relación con dicha materia prima, de modo que se forma una mezcla reactiva; y (c) añadir a dicha mezcla reactiva desde aproximadamente 2 a aproximadamente 5 equivalentes de agua en relación con dicho óxido de calcio de manera que dicho óxido de calcio hidrata y neutraliza a dichos ácidos grasos para formar sales cálcicas.
Patent ES-2030649-T1 (ES)
Title: Perfeccionamientos en cochecitos plegables para ninos.
IPC: B62B7/00
Filed: 1991-08-23
Abstract: COCHECITO PLEGABLE PARA NIÑO, QUE LLEVA UN CHASIS RODANTE SUSCEPTIBLE DE ESTAR REPLEGADO Y DESPLEGADO PARA SERVIR DE SOPORTE O UNA GONDOLA O HAMACA MONTADO SOBRE EL CHASIS CON INCLINACION AJUSTABLE Y DE MANERA REVERSIBLE, COMPRENDIENDO EL CHASIS DOS CONJUNTOS LATERALES CADA UNO DE LOS CUALES SE COMPONE DE UNA PATA FRONTAL (11) Y UNA PATA TRASERA (12) ASI COMO DE UN BRAZO (10) DIRIGIDO SENSIBLEMENTE PARALELAMENTE A LA PATA FRONTAL Y DESTINADO A DESLIZARSE RESPECTO DE BRAZO MEDIANTE UN MANGUITO (13) QUE LLEVA UNA PARTE DE LOS MEDIOS (M) DE MONTAJE DE LA HAMACA (H) SOBRE EL CHASIS (C), ESTANDO DOTADA LA PATA TRASERA EN SU EXTREMO INFERIOR DE UNA ARTICULACION DE HORQUILLA (18) SOBRE LA QUE ESTA ARTICULADA UNA BIELA (19) TAMBIEN ARTICULADA ALREDEDOR DE UN EJE (20) SOLIDARIA DEL MANGUITO. LA ARTICULACION (18) QUE LLEVA LA PATA TRASERA (12) ESTA MONTADA DESLIZANTE SOBRE DICHA PATA ENTRE UN TOPE BAJO (21) Y UN TOPE ALTO (22), ESTANDO CONSTANTEMENTE SOLICITADA POR UN MUELLE DE RECUPERACION (23).
Patent ES-2038107-T1 (ES)
Title: Cojinete de aros delgados con sitio de separacion y procedimiento para fabricar tal cojinete.
IPC: F16C33/60
Filed: 1992-07-21
Abstract: PARA PODER FABRICAR UN SOPORTE ANULAR DELGADO CON UNA SECCION DEL SOPORTE RECTANGULAR, CON PREFERENCIA CUADRADA DE MODO SENCILLO Y CON POCO COSTE, SIN QUE SE DEBA REDUCIR LA CALIDAD DEL SOPORTE, PRESENTAN LOS ANILLOS DEL SOPORTE (1,2) POR LO MENOS UN PUNTO DE SEPARACION (6), ESTAN FABRICADOS SIN VIRUTAS DE MATERIAL PERFILADO Y LAS PISTAS DE RODADURA (3,4) ESTAN SOMETIDAS A CONTINUACION O SIMULTANEAMENTE A UN MECANIZADO CON O SIN ARRANQUE DE VIRUTAS.
Patent ES-2076909-T1 (ES)
Title: Sellante de un componente intumescente.
Inventor: JOACHIMI ROLAND
IPC: C09K3/10
Filed: 1993-09-15
Abstract: LA INVENCION ES RELATIVA A UN SELLANTE INTUMESCENTE DE UN COMPONENTE BASADO SOBRE POLIURETANO Y QUE CONTIENE UN AGENTE INTUMESCENTE Y UN RELLENADOR VITREO FUNDIBLE. EL AGENTE INTUMESCENTE Y EL RELLENADOR VITREO HAN SIDO PRETRATADOS POR REACCION CON UN ISOCIANATO QUE TIENE UNA FUNCIONALIDAD DE AL MENOS 2. EL SELLANTE ES ESTABLE EN ALMACENAMIENTO Y ES UNA BARRERA EFECTIVA CONTRA EL FUEGO EN EL CASO DE INCENDIO.
Patent ES-2097722-T1 (ES)
Title: Un conjunto de herramientas de corte.
Inventor: SATRAN AMIR
IPC: B23B31/00
Filed: 1996-05-10
Abstract: UN ENSAMBLAJE DE HERRAMIENTA QUE CONSTA DE PRIMERAS Y SEGUNDAS UNIDADES DE ENSAMBLAJE FORMADAS CON ELEMENTOS DE UNION MACHOS (7) Y HEMBRAS (17) INTERCONECTADOS, UNIDOS COAXIALMENTE ENTRE SI PARA TENER UN EJE LONGITUDINAL COMUN, EN DONDE UN MOMENTO TRANSMITIDO A LA PRIMERA UNIDAD SE TRANSMITE A LA SEGUNDA. CADA ELEMENTO DE UNION CONSTA DE UN COMPONENTE DE TRANSMISION DE TORSION (9,19) QUE TIENE UNA PARTE CENTRAL (11,11'') CON UNA DIMENSION RADIAL DEFINIDA POR EL RADIO DE UN CIRCULO INSCRITO EN LA MISMA, Y AL MENOS UN BRAZO QUE SE EXTIENDE DESDE LA PARTE CENTRAL A LA PERIFERIA DEL ELEMENTO DE UNION CORRESPONDIENTE. LOS BRAZOS (12,12'') DE LOS ELEMENTOS DE UNION MACHOS Y HEMBRAS TIENEN PRIMERAS PAREDES LATERALES (26,26'') CON UN ESPACIO ENTRE LAS MISMAS. LAS PRIMERAS PAREDES ESTAN DIRIGIDAS, AL MENOS EN SUS REGIONES DE CONTACTO (35), SUSTANCIALMENTE DE FORMA RADIAL CON RESPECTO AL EJE LONGITUDINAL. LA SEGUNDA PARED LATERAL DE AL MENOS UN BRAZO DE AL MENOS EL ELEMENTO DE UNION MACHO ESTA ORIENTADADE MANERA QUE UN NORMAL CAPTADO DEL EJE LONGITUDINAL NO SEA MAS CORTO QUE EL RADIO DEL CIRCULO INSCRITO EN LA PARTE CENTRAL DEL ELEMENTO DE UNION MACHO.
Patent CY-1108155-T1 (CY)
Title: Βενζοαζωλυλοπιπεραζινικα παραγωγα τα οποια εχουν δραστικοτητα vr1-ανταγωνιστη
Inventor: SUN QUN
IPC: A61P29/00
Filed: 2008-06-24
Abstract: Μια ένωση του τύπου (I) όπου τα Ar1, A, R3, x και m είναι όπως γνωστοποιούνται στο παρόν και το Ar2 είναι μια βενζοθειαζολυλική, βενζοοξαζολυλική, ή βενζοϊμιδαζολυλική ομάδα ή ένα φαρμακευτικώς αποδεκτό άλας αυτής (μια «Βενζοαζωλυλοπιπεραζινική Ένωση»), συνθέσεις οι οποίες περιλαμβάνουν μια Βενζοαζωλυλοπιπεραζινική Ένωση, και μέθοδοι για αντιμετώπιση ή πρόληψη πόνου, UI, ενός έλκους, IBD, IBS, μιας διαταραχής εθισμού, νόσου του Parkinson, παρκινσονισμού, άγχους, επιληψίας, εγκεφαλικού επεισοδίου, μιας κρίσης, μιας κνιδωτικής πάθησης, ψύχωσης, μιας γνωσιακής διαταραχής, ενός ελλείμματος μνήμης, περιορισμένης εγκεφαλικής λειτουργίας, χορείας του Huntington, αμυοτροφικής πλευρικής σκλήρυνσης, άνοιας, αμφιβληστροειδοπάθειας, ενός μυϊκού σπασμού, μιας ημικρανίας, εμετού, δυσκινησίας ή κατάθλιψης σε ένα ζώο οι οποίες περιλαμβάνουν τη χορήγηση σε ένα ζώο το οποίο έχει ανάγκη αυτής μιας αποτελεσματικής ποσότητας Βενζοαζωλυλοπιπεραζινικής Ένωσης γνωστοποιούνται.
Patent CY-1110065-T1 (CY)
Inventor: RUYMEN MARC J
IPC: G01N21/00
Filed: 2010-03-22
Abstract: An apparatus for sorting products moving through a detection zone directs a light beam having a given cross sectional area towards a scanning zone through which the products move and are impinged upon by the light beam. A first detector is disposed to receive reflected light back from the products and has a first field of view larger than the light beam cross sectional area, the first detector being sensitive to substantially all of the direct and diffused reflected light from the products and generating a first signal corresponding thereto. A second detector also receives the reflected light and has a second field of view generally equal to the cross sectional area of the light beam. The second detector is sensitive to substantially only the direct reflected light from the products and generates a second signal corresponding thereto. Control circuitry causes a removal mechanism to remove impurities o products from the stream of products based on the signals from the first and second detectors individually or a difference between the signals.
Patent CY-1111351-T1 (CY)
Title: Παραγωγα κινικλιδινης απο (ετερο) αρυλκυκλοεπτανοκαρβοξυλικο οξυ ως ανταγωνιστες μουσκαρινικου υποδοχεως
Inventor: FORD RHONAN
IPC: C07D453/02
Filed: 2011-03-22
Abstract: Η εφεύρεση παρέχει ενώσεις του τύπου (I) όπου το R4 είναι μία ομάδα του τύπου (II) ή του (IIIa) ή του (IIIb) και τα R1, R2, R3, R5, a, b και Χ είναι όπως ορίζονται στην περιγραφή, μία διαδικασία για την παρασκευή τους, φαρμακευτικές συνθέσεις που τις περιέχουν, μία διαδικασία για την παρασκευή φαρμακευτικών συνθέσεων, τη χρήση του στη θεραπεία και ενδιάμεσες ενώσεις για χρήση στην παρασκευή τους των (I), (II), (IIIa), (IIIb).
Patent CY-1115352-T1 (CY)
Title: Μεθοδος παραγωγης ισοτοπου
Inventor: KARLSON JAN ROGER
IPC: A61K51/12
Filed: 2014-06-18
Abstract: Η παρούσα εφεύρεση σχετίζεται με μία μέθοδο για την παραγωγή 223Ra φαρμακευτικώς ανεκτής καθαρότητας η οποία περιλαμβάνει: i) την παρασκευή ενός μείγματος παραγωγής το οποίο περιλαμβάνει 227Ac, 227Th και 223Ra σε ένα πρώτο υδατικό διάλυμα το οποίο περιλαμβάνει ένα πρώτο ανόργανο οξύ˙ ii) την φόρτωση του εν λόγω μείγματος παραγωγής σε ένα DGA μέσο διαχωρισμού (π.χ., ρητίνη)˙ iii) την έκλουση του εν λόγω 223Ra από το εν λόγω DGA μέσο διαχωρισμού χρησιμοποιώντας ένα δεύτερο ανόργανο οξύ σε ένα δεύτερο υδατικό διάλυμα για να δώσει ένα εκλουόμενο 223Ra διάλυμα˙ και iv) την απογύμνωση του DGA μέσου διαχωρισμού από τα εν λόγω 227Ac και 227Th με ροή ενός τρίτου ανόργανου οξέος σε ένα τρίτο υδατικό διάλυμα μέσω του DGA μέσου διαχωρισμού σε μια αντίστροφη κατεύθυνση. Η εφεύρεση περαιτέρω σχετίζεται με υψηλής-καθαρότητας ράδιο-223 σχηματιζόμενο ή δυνάμενο να σχηματιστεί με μια τέτοια μέθοδο καθώς επίσης φαρμακευτικές συνθέσεις οι οποίες περιλαμβάνουν τέτοιο ράδιο-223 φαρμακευτικής καθαρότητας.
Patent CY-1117236-T1 (CY)
Title: Μονοκλωνικα αντισωματα εναντι γλυπικανης-3
Inventor: TERRETT JONATHAN ALEXANDER
IPC: C07K16/30
Filed: 2016-03-01
Abstract: Η παρούσα αποκάλυψη παρέχει απομονωθέντα μονοκλωνικά αντισώματα, ιδιαιτέρως ανθρώπινα μονοκλωνικά αντισώματα που συνδέονται ειδικώς προς Γλυπικάνη-3 με υψηλή συνάφεια. Επίσης παρέχονται μόρια νουκλεϊνικού οξέος που κωδικοποιούν αντισώματα Γλυπικάνης-3, φορείς έκφρασης, κύτταρα ξενιστές και μέθοδοι για έκφραση των αντισωμάτων Γλυπικάνης-3. Επίσης παρέχονται ανοσο-προϊόντα σύζευξης, διπλά-ειδικά μόρια και φαρμακευτικές συνθέσεις που περιλαμβάνουν τα αντισώματα Γλυπικάνης-3. Αποκαλύπτονται μέθοδοι για ανίχνευση Γλυπικάνης-3, καθώς επίσης μέθοδοι για θεραπεία διαφόρων καταστάσεων σχετικών με Γλυπικάνη-3, συμπεριλαμβανομένου ηπατοκυτταρικού καρκίνου.