baber/WOPTO huggingface dataset:
Patent CA-2878241-A1 (CA)
Inventor: FUNK BENJAMIN E
IPC: G01C22/00
Filed: 2013-06-07
Abstract: A system and method for recognizing features for location correction in Simultaneous Localization And Mapping operations, thus facilitating longer duration navigation, is provided. The system may detect features from magnetic, inertial, GPS, light sensors, and/or other sensors that can be associated with a location and recognized when revisited. Feature detection may be implemented on a generally portable tracking system, which may facilitate the use of higher sample rate data for more precise localization of features, improved tracking when network communications are unavailable, and improved ability of the tracking system to act as a smart standalone positioning system to provide rich input to higher level navigation algorithms/systems. The system may detect a transition from structured (such as indoors, in caves, etc.) to unstructured (such as outdoor) environments and from pedestrian motion to travel in a vehicle. The system may include an integrated self-tracking unit that can localize and self- correct such localizations.
Patent CA-2879084-A1 (CA)
Inventor: SIEBER INGO
IPC: A61F2/16
Filed: 2013-07-18
Abstract: Wide-angle optical unit for ophthalmological implants in the eye. The problem is that of designing the wide-angle optical unit such that it does not restrict sight in a central field of vision and at the same time also ensures peripheral vision of the implant bearer. The problem is solved by a wide-angle optical unit comprising a lens system (2) arranged rotationally symmetrically about an optical axis (5), comprising at least two lenses (8-12) lying areally one on another and composed of materials having different optical refractive indexes, and also a lens (4) which is arranged proximally with respect to the inside of the eye and around which an optical coupling-out structure (6) is placed.
Patent CA-2886097-A1 (CA)
Title: Methods for alleviating symptoms of multiple sclerosis based on apoaequorin-containing compositions
Inventor: UNDERWOOD MARK Y
IPC: A61K38/44
Filed: 2013-09-27
Abstract: Methods for alleviating symptoms related to Multiple Sclerosis by administration of apoaequorin are provided by the present invention. Such symptoms include, for example, sleep quality, energy quality, mood quality, memory quality or pain.
Patent CA-2888135-A1 (CA)
Title: Delivery of small interfering rna and micro rna through membrane-disruptive, responsive nanoscale hydrogels
Inventor: PEPPAS NICHOLAS
IPC: A61K9/06
Filed: 2013-10-14
Abstract: Nanoscale, pH-responsive polycationic networks useful for the delivery of anionic biologic therapeutics and associated methods.
Patent CA-2888877-A1 (CA)
Inventor: MOHILE SWAPNIL SURENDRA
IPC: C07C229/24
Filed: 2013-11-04
Abstract: The present invention provides an improved process for the preparation of a compound of formula (I), which comprises the steps of: formula (I), (a) reacting isovaleraldehyde of formula (II) and alkyl cyanoacetate of formula (III) optionally in presence of salts of weak acid and weak base or weak base in a suitable solvent to get 2-cyano-5- methyl-hex-2-enoic acid alkyl ester of formula (IV); (b) reacting 2-cyano-5-methyl-hex-2-enoic acid alkyl ester of formula (IV) with a suitable cyanide source in water or in an organic solvent or mixture thereof to get 2-isobutylsuccinonitrile of formula (V); (c) obtaining optionally 2-isobutylsuccinonitrile of formula (V) by reacting isovaleraldehyde of formula (II) and alkyl cyanoacetate of formula (III) in presence of suitable cyanide source in water or in an organic solvent or mixture thereof in single step; (d) converting 2-isobutylsuccinonitrile of formula (V) to racemic 3-cyano-5-methyl-hexanoic acid or salt thereof of formula (VI) with a genetically modified nitrilase enzyme (Nit 9N_56_2) in water or optionally with an organic co-solvent at appropriate pH and temperature; (e) converting racemic 3-cyano-5-methyl-hexanoic acid or salt thereof of formula (VI) to racemic alkyl 3-cyano-5-methyl-hexanoate of formula (VII) by treatment with alcohol (R3OH) and acidic catalyst or alkyl halide (R3X) in presence of a base in a suitable solvent or a mixture of solvents thereof;.(f) obtaining (S)-alkyl 3 -cyano-5 -methyl -hexanoate of formula (VIII) and (R)-3-cyano-5-methyl- hexanoic acid or salt thereof of formula (X) by enzymatic enantioselective hydrolysis in water or organic solvent or a mixture thereof from racemic alkyl 3-cyano-5-methyl-hexanoate of formula (VII);.(g) obtaining optionally the compound of formula (VII) by racemizing unwanted (R)-3-cyano-5- methyl-hexanoic acid or salt thereof of formula (X) or substantially enriched (R)-3 -cyano-5 - methyl-hexanoic acid salt thereof of formula (X) in presence of a base in organic solvent or a mixture thereof; (h) converting (S)-alkyl 3-cyano-5-methyl-hexanoate of formula (VIII) to pregabalin of formula (I) by hydrolyzing ester group with suitable alkali or alkaline earth metal base followed by hydrogenation optionally in one pot in a solvent selected from water or other organic solvents or a mixture thereof in presence of a suitable hydrogenation catalyst.
Patent CA-2892207-A1 (CA)
Inventor: SAMPAOLI DAVIDE
IPC: A47J31/36
Filed: 2015-05-20
Abstract: An improved device for wetting a dose of ground coffee in coffee machines, preferably espresso machines, particularly but without limitation professional espresso making machines. The device comprises a source of pressurized water (4), at least one beverage dispenser unit (13), a filter holder (15) removably coupled to said dispenser (13), a water heater (12) placed on the dispenser unit, a water supply system (3, 11) connecting said source of pressurized water (4) with said heater (12), a dispensing conduit (23) connecting the heater (12) with the dispenser unit (13), as well as a dispensing valve device (26) inserted in said dispensing conduit (23) for closing and opening the conduit and for feeding heated water to the filter holder (15) and cause it to spread into the dose of ground coffee contained in the filter holder, as well as an electronic control and programming unit (22) connected at least with said source of pressurized water (4), with said heater (12) and with said dispensing valve device (26). The device further comprises an additional valve device (28) located on said water supply system (3, 11) which connects said source of pressurized water (4) with said heater (12), said additional valve device (28) being connected to said electronic control and programming unit.
Patent CA-2892407-A1 (CA)
Title: Remote hash generation in a system and method for providing code signing services
Inventor: RYBAK MICHAEL A
IPC: H04W12/10
Filed: 2006-09-29
Abstract: A system and method for providing code signing services to software application developers or to other individuals or entities that wish to have applications digitally signed. Signing of the applications may be required in order to enable the applications to access sensitive APIs and associated resources of a computing device when the applications are executed on the computing device. In one embodiment, a hash of an application is generated by a requestor of code signing services. The hash of the application, and not the application itself, may then be received in a code signing request to be digitally signed.
Patent CA-2893419-A1 (CA)
Inventor: STRONG ANTHONY JAMES
IPC: C10M161/00
Filed: 2015-06-02
Abstract: A lubricating oil composition having a sulphated ash content of less than or equal to 1.2 mass % as determined by ASTM D874 and a phosphorous content of less than or equal to 0.12 mass % as determined by ASTM D5185, which lubricating oil composition comprises or is made by admixing: an oil of lubricating viscosity, in a major amount; an oil-soluble or oil-dispersible polymeric friction modifier as an additive in an effective minor amount; and, at least one oil-soluble or oil-dispersible molybdenum compound as an additive in an effective minor amount.
Patent CA-2894685-A1 (CA)
Title: Apparatus and method to reduce a rate of receiving data
Inventor: SMADI MOHAMMED NAWAF
IPC: H04W80/02
Filed: 2015-06-19
Abstract: These teachings provide for transmitting to a wireless access point a sleep status indicator for a wireless transceiver. These teachings then provide for delaying having that wireless transceiver enter a sleep mode of operation until at least a predetermined period of time following transmission of the wireless transceiver sleep status indicator. These teachings also provide for determining a need to slow down a rate of receiving data from the wireless access point via the wireless transceiver. In this case the aforementioned sleep status indicator is transmitted in response to determining that need to slow down the rate of receiving data from the wireless access point.
Patent CA-2899932-A1 (CA)
Inventor: ARAYA SIMON
IPC: H04N5/225
Filed: 2015-08-07
Abstract: A recording system for an emergency response unit includes a first data collection device configured to record a first video, audio or data segment with an incident identifier and transmit a message including the incident identifier. A second data collection device may receive the message and, as appropriate, record at least a second video, audio or data segment with the incident identifier, allowing the first segment and the second segment to be associated using the incident identifier. In other embodiments, a first recording device may begin recording video, audio or legal evidence data with an incident identifier, and a control system may receive a message including the incident identifier from the first recording device, identify one or more additional recording devices located within a certain distance of the first recording device, and obtain recordings from the one or more additional recording devices.
Patent CA-2900380-A1 (CA)
Inventor: KATZ STEVEN C
IPC: C12N15/00
Filed: 2014-02-04
Abstract: The invention features nucleic acid constructs encoding chimeric immunoreceptors (CIRs) that are useful for treating a KIT+ associated disease in patients. In general, the CIRs contain an extracellular domain (e.g., a KIT-ligand (KL) or stem cell factor (SCF)) which interacts with and destroys KIT+ tumor cells, a transmembrane domain, and a cytoplasmic domain for mediating T cell activation (e.g., CD3 zeta and/or the domain of CD28). The invention also features the use of the nucleic acid constructs and/or host cells expressing CIRs in the treatment of a KIT+ associated disease, in particular gastrointestinal stromal tumor (GIST).
Patent CA-2900986-A1 (CA)
Inventor: WINKENS PEDRO E
IPC: B65B51/06
Filed: 2014-02-12
Abstract: A dunnage conversion system includes a machine for converting a stock material (14) into a strip of relatively lower-density dunnage, a coiling mechanism (20) for winding the strip into a coil, a taping mechanism (22) for automatically securing a trailing end of the strip to the coil, and a coil ejecting mechanism (24) for automatically removing the coil from the coiling mechanism.  The taping mechanism includes a guide surface (70) between an outlet of the machine and the coiling mechanism to guide the strip to the coiling mechanism and to guide tape for engagement with a trailing end of the strip and to secure the trailing end of the strip to the coil. The coil ejecting mechanism includes a lever arm (126) that pivots to push the completed coil off the coiling mechanism.
Patent CA-2901543-A1 (CA)
Inventor: HOULDSWORTH JANE C
IPC: C12Q1/68
Filed: 2014-02-14
Abstract: The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly urogenital cancers. The microarray can include a plurality of genomic regions represented thereon, the genomic regions corresponding to regions wherein alterations, such as copy number aberrations, at such locations correlate to specific, identifiable cancers, particularly prostate, renal, or bladder tumors. The invention further provides methods of diagnosing certain types of cancers, particularly urogenital cancers, more particularly renal cortical cancers. The methods can comprise analyzing genetic material from a human individual to determine the presence or presence of certain aberrations and using a decision tree to classify the subtype of renal cortical neoplasm present in the sample.
Patent CA-2903004-A1 (CA)
Inventor: ROS JACQUELINE
IPC: G08B21/02
Filed: 2015-09-04
Abstract: An apparatus for personal security includes a portable accessory 102 formed to receive an alerting device 104. The alerting device 104 fits within a compartment of the portable accessory 102, and the portable accessory 102 includes a communication device 152. The apparatus includes an alerting device 104 with an alerting element. The alerting device 104 is interchangeable with a plurality of portable accessories 102, 112, 122, 142, 152. One or more activation elements 106 are disposed on the portable accessory 102 and formed to activate the alerting device 104 wherein the alerting element sends an alert signal to the communication device 152 in response to receiving an activation signal from the one or more activation elements 106.
Patent CA-2903252-A1 (CA)
Inventor: GEHLSEN KURT R
IPC: C12P21/00
Filed: 2014-03-03
Abstract: The present application relates to modified T cell epitopes derived from fungal ribotoxins, including a-sarcin, clavin, gigantin, mitogillin, and restrictocin, as well as modified ribotoxin molecules comprising one or more of the modified epitopes. The modified ribotoxin molecules inhibit protein synthesis, like the wild type ribotoxins, but exhibit reduced immunogenicity as compared to the corresponding wild type ribotoxin. Another aspect relates to a fusion protein which comprises a modified ribotoxin fused or conjugated or otherwise linked to a targeting molecule that is effective for binding a target of interest. Another aspect relates to the use of the modified ribotoxin or fusion protein for treating or managing a disease or condition.
Patent CA-2903452-A1 (CA)
Inventor: FONSECA BENEDITO J JR
IPC: G10L25/54
Filed: 2014-03-07
Abstract: An apparatus comprising a microphone capable of receiving a local audio signal comprising primary audio and extraneous audio, at least one processor communicatively coupled to a transmitter, and a receiver. The processor is configured to (i) analyze said received local audio signal to identify a presence or absence of corruption in the received local audio signal; (ii) generate an audio signature of the received local audio signal over a temporal interval based on the identified presence or absence of corruption in the received local audio signal; (iii) modify and said processor modifies said audio signature by nullifying those portions of said audio signature corrupted by said extraneous audio; and (iv) communicate said audio signature, via the transmitter, to a server.
Patent CA-2903477-A1 (CA)
Inventor: MEEKS ARTHUR WARREN
IPC: E21B37/00
Filed: 2014-03-13
Abstract: A downhole tool for use in a wellbore having a tool body with a blade assembly slidably mounted thereon and movable between a retracted and an outwardly extended position. The blade assembly is biased towards the retracted position and movable with an actuating force to the extended position. The tool includes an indexer constructed and arranged to facilitate movement of the blade assembly.
Patent CA-2903574-A1 (CA)
Inventor: STEPHEN ANTHONY R
IPC: C08F4/80
Filed: 2014-03-14
Abstract: The present invention relates to in-mold coating of a cyclic olefin polymer. More particularly, the present invention relates to methods and compositions for in-mold coating cyclic olefin polymers prepared by ring opening metathesis polymerization (ROMP) reactions and the manufacture of polymer articles via ROMP. Polymer products produced via the metathesis reactions of the invention may be utilized for a wide range of materials and composite applications. The invention has utility in the fields of polymer and material chemistry and manufacture.
Patent CA-2906033-A1 (CA)
Title: Particle foam component having a textured surface
Inventor: MAIDL JANJA
IPC: C08J9/232
Filed: 2014-03-13
Abstract: An element molded from a particle foam, including for example expanded polypropylene foam, includes at least one visible exterior surface defined by the particle foam. The visible exterior surface is textured having a roughness depth of less than or equal to 1.00mm and a plurality of vent interfaces each having a maximum width of less than or equal to 0.4mm. Methods of molding the element, together with a mold and a method of making the mold, are also provided.
Patent CA-2908406-A1 (CA)
Inventor: TEUFEL DANIEL PAUL
IPC: A61K47/48
Filed: 2014-04-11
Abstract: The invention describes peptide ligands specific for human plasma Kallikrein.
Patent CA-2910947-A1 (CA)
Inventor: KOHLER DALLAS
IPC: G02B5/08
Filed: 2015-11-02
Abstract: Described herein is a mirror apparatus comprising: a reflective substrate; and an anti-fog complex comprising: an adhesive layer atop the substrate; a first polymeric layer atop the pressure sensitive adhesive layer; and a second polymeric layer atop the first polymeric layer. Methods of making the mirror apparatus are also disclosed.
Patent CA-2914033-A1 (CA)
Inventor: TALBOT JOHN
IPC: B42D15/02
Filed: 2015-12-03
Abstract: An interactive greeting card with a multi-panel insert which can be unfurled over a portion of the greeting card. In one embodiment, there is a photo or drawing of a character or animal printed on the front cover. A tab is located to the left of and behind the photo or drawing. When a user grasps and moves the tab, a multi-panel paper construct unfurls around the photo or drawing and appears as a wig atop the head of the character or animal depicted in the photo or drawing. Audio replay may also triggered by moving the tab from its original position. In another embodiment, the panels of the multi-panel paper construct are each shaped like a different item or object which is complementary to the theme of the greeting card. Unfolding the multi-panel construct along an outside edge of the greeting card may initiate audio playback and may also activate a motor module which causes movement to at least one mobile object contained on the greeting card.
Patent CA-2914527-A1 (CA)
Title: Coaxial direct-detection lidar system
Inventor: RODRIGO PETER JOHN
IPC: G01S7/491
Filed: 2014-05-06
Abstract: The invention relates to a coaxial direct-detection LIDAR system for measuring velocity, temperature and/or particulate density. The system comprises a laser source for emitting a laser light beam having a lasing center frequency along an emission path. The system further comprises an optical delivery system arranged in the emission path of the laser source, the optical delivery system being arranged for delivering the laser light beam in a measuring direction, the optical delivery system further being configured for collecting a return signal backscattered along the measuring direction. Finally, the system comprises a detector system arranged to receive the return signal from the optical delivery system, the detector system comprising a narrowband optical filter and a detector, the narrowband optical filter having a filter center frequency of a pass-band, wherein the center lasing frequency and/or the center filter frequency may be scanned. The invention further relates to an aircraft airspeed measurement device, and a wind turbine airspeed measurement device comprising the LIDAR system.
Patent CA-2915627-A1 (CA)
Inventor: BLOCH KENNETH D
IPC: C12N15/113
Filed: 2013-06-14
Abstract: The present invention relates to methods, kits and compositions to treat hypertension and other cardiovascular diseases in a subject, in particular, a method of treating or preventing a cardiovascular disease in a subject comprising administering to a subject at least one anti-miR agent to miRNA-425. In some embodiments, an anti-miR agent is a small molecule or an oligonucleotide complementary to at least part of the miR-425 of SEQ ID NO: 1, or an anti-miR complementary to at least part of the miRNA seed sequence AUGACA (SEQ ID NO: 2). Another aspect of the present invention relates to methods, kits and compositions to treat low blood pressure in a subject comprising administering a composition comprising a miR-425 agent to decrease ANP levels in the subject. Other aspects of the present invention relates to assays, methods and systems to identify a subject at risk of hypertension, or identifying a subject suitable to administration of an anti-miR-425 agent for treatment of hypertension, the assay comprising assessing if a subject is homozygous or heterozygous for the major (A) allele of rs5068 SNP, and/or assaying for levels of miR-425 and/or assaying for levels of NT-proANP and/or levels of ANP in the plasma of a subject.
Patent CA-2915765-A1 (CA)
Inventor: STIGSSON LARS
IPC: C01D5/00
Filed: 2014-06-27
Abstract: The present invention concerns a method for the recovery of solvent in a process for preparation of regenerated cellulosic fibers using sodium hydroxide as solvent for cellulose dissolving in the manufacturing of a cellulose spinning dope wherein sodium hydroxide present in the spinning dope is at least partially recovered and recycled as sodium hydroxide from a cellulose fiber regeneration or cellulose coagulation step and wherein said cellulose fiber regeneration or cellulose coagulation step consists of a bath into which cellulose spinning dope is injected. Recovered sodium hydroxide may be directly or indirectly recycled from a cellulose fiber regeneration or cellulose coagulation step to a cellulose dissolving step.
Patent CA-2916254-A1 (CA)
Inventor: LEPINE KRISTOPHER W
IPC: B01D46/24
Filed: 2014-06-24
Abstract: L'invention concerne un ensemble de filtre et un élément filtrant. L'ensemble de filtre comprend un logement dans lequel est disposé un élément filtrant. L'ensemble de filtre comprend également un tuyau d'entrée indépendant et amovible qui fait saillie d'une partie intérieure du logement à une partie extérieure du logement à travers une ouverture dans un couvercle du logement. L'élément de filtre comprend un anneau de milieu filtrant avec des constructions de coiffes d'extrémités supérieure et inférieure fixées à des extrémités opposées de l'anneau de milieu filtrant. La construction de coiffe d'extrémité supérieure comprend une partie de base et une partie de joint axial s'étendant en sens axial à partir de la partie de base. La construction de coiffe d'extrémité inférieure comprend un anneau de support et une partie élastique.
Patent CA-2916400-A1 (CA)
Title: Process for cracking of liquid hydrocarbon materials by pulsed electrical discharge and device for its implementation
Inventor: NOVOSELOV YURY
IPC: C10G15/08
Filed: 2014-06-20
Abstract: A carrier gas jet is injected into a liquid hydrocarbon material to form a liquid hydrocarbon-gas mixture; flowing the liquid hydrocarbon- gas material through an inter-electrode gap of a discharge chamber, the inter-electrode gap defined by a spaced pair of electrodes, the electrodes being connected to a capacitor; charging the capacitor to a breakdown voltage of the carrier gas; generating a spark discharge in the inter-electrode gap; and recovering a hydrocarbon fraction that includes lower molecular weight hydrocarbons than the liquid hydrocarbon material.
Patent CA-2916678-A1 (CA)
Inventor: VON MALTZAHN GEOFFREY
IPC: A01G7/06
Filed: 2014-06-26
Abstract: La présente invention concerne des procédés et des substances pour procurer un bénéfice à une semence ou un semis de plante agricole (par exemple, une herbe agricole), ou plante agricole dérivée de la semence ou du semis. Par exemple, la présente invention concerne des populations de bactéries purifiées qui comprennent des endophytes bactériens provenant de semences, et des combinaisons synthétiques de semences et/ou de semis (par exemple, des semences et/ou semis de céréales) avec des endophytes bactériens hétérologues dérivés de semences.