baber/WOPTO huggingface dataset:
Patent CA-2851855-A1 (CA)
Inventor: RYDING NICHOLAS J
IPC: C12N15/80
Filed: 2012-10-31
Abstract: The present disclosure is directed to the use of plant promoters to drive recombinant expression in filamentous fungal cells. In certain aspects, the present disclosure provides an expression cassette useful for the expression of polypeptide in filamentous fungal cells. Also provided herein, are vectors and recombinant filamentous fungal cells comprising the expression cassettes of the present disclosure, and methods of making and using the same for recombinant polypeptide expression.
Patent CA-2852303-A1 (CA)
Title: Wear assembly
Inventor: JOHNSTON CHRISTOPHER A
IPC: E02F9/28
Filed: 2012-11-16
Abstract: A wear member for ground-engaging equipment comprising a hole extending from an exterior surface to an interior surface and having a rear wall with a support projecting forwardly into the hole for a lock, which holds or releases the wear member to or from the equipment. The hole having a front wall opposite the rear wall, the front wall having an outer portion extending from the exterior surface toward the interior surface, and an inner portion between the outer portion and the interior surface, the outer portion including a recess formed by a first surface for receiving a latch portion of the lock to retain the lock in a release position, and the inner portion including a pocket formed by a second surface inward of the first surface for receiving a latch portion of the lock to retain the lock in the inwardly swung position.
Patent CA-2852954-A1 (CA)
Inventor: PRINCEN FRED
IPC: G16B40/00
Filed: 2012-10-19
Abstract: Methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more serogenetic-inflammation markers are disclosed. With these methods it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and DC, and to differentiate between CD and DC with increased accuracy.
Patent CA-2854648-A1 (CA)
Inventor: THORLEY CRAIG STEPHEN
IPC: A61M5/32
Filed: 2012-11-09
Abstract: A retractable needle is provided for a syringe comprising a barrel and a plunger that comprises a portion capable of engaging the retractable needle for retraction. The retractable needle comprises a cannula, a needle body having a plunger-engaging member, at least one aperture and an elongate portion which houses the cannula, the cannula comprising an end which is in fluid communication with the at least one aperture, wherein the at least one aperture is located between the plunger-engaging member and the elongate portion. The positioning of the at least one aperture distal to the plunger-engaging member maximizes the efficiency of fluid delivery.
Patent CA-2855394-A1 (CA)
Inventor: WICKELMAIER PETER
IPC: F24H9/00
Filed: 2014-07-02
Abstract: A pressure compensation and mixing device for a fluid heater has a mixing unit and a pressure compensation unit, wherein the mixing unit is used for mixing a fluid guided in the mixing unit and wherein the pressure compensation unit is used for homogenization of the pressure in the fluid. The mixing unit and the pressure compensation unit are integrated in a housing which allows for a compact structure. By the mixing unit a specific homogenization of the temperature of the water heated by the fluid heater is achieved.
Patent CA-2855498-A1 (CA)
Inventor: VISENTIN GIAN PAOLO
IPC: C07K14/755
Filed: 2012-11-09
Abstract: Dans un premier aspect, l'invention concerne un substrat polypeptidique isolé pour une métallopeptidase de type disintégrine ayant un motif de type 1 de la thrombospondine, 13 (ADAMTS13), qui a une longueur de 45 à 70 acides aminés et a une séquence d'acides aminés qui est sensiblement similaire à une partie de la séquence du domaine A2 du facteur de von Willebrand présentée dans SEQ ID NO:2, avec une ou plusieurs des modifications suivantes : (i) l'acide aminé correspondant à la position 1599 de SEQ ID NO: 2 est muté de Q à K ; (ii) l'acide aminé correspondant à la position 1610 de SEQ ID NO: 2 est muté de N à C ; et (iii) les acides aminés correspondant à Q1624 à R1641 de SEQ ID NO:2 sont délétés. Dans un autre aspect, l'invention concerne un substrat polypeptidique ADAMTS13 qui a une longueur de 50 à 75 acides aminés et a une séquence d'acides aminés qui est sensiblement similaire à une partie de la séquence du domaine A2 du facteur de von Willebrand présentée dans SEQ ID NO:2, avec une ou plusieurs des modifications suivantes : (i) l'acide aminé correspondant à la position 1599 de SEQ ID NO:2 est muté de Q à K ; (ii) l'acide aminé correspondant à la position 1610 de SEQ ID NO:2 est muté de N à C ; (iii) l'acide aminé correspondant à la position 1629 de SEQ ID NO:2 est muté de G à E ; et (iv) les acides aminés correspondant à G1631 à R1641 de SEQ ID NO:2 sont délétés.
Patent CA-2855824-A1 (CA)
Inventor: DUNBAR WILLIAM
IPC: H01L49/00
Filed: 2012-11-13
Abstract: Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
Patent CA-2856031-A1 (CA)
Inventor: HOLTMANN LUDGER
IPC: F04C15/00
Filed: 2014-07-08
Abstract: A pump is proposed, having at least one suction region and at least one pressure region, a pressure space which has an outflow region to a consumer, a rotor which is operatively connected to a shaft which rotates about a rotational axis, in which rotor delivery elements are received displaceably, as viewed in the radial direction, the rotor having expelling regions radially within the delivery elements, which expelling regions are connected at least partially to the pressure region by way of a first fluid path, and having a cold starting device which comprises a cold starting element which is prestressed into a first functional position and, in its first functional position, shuts off a second fluid path from the pressure region to the pressure space, the cold starting element opening the second fluid path in a second functional position, the cold starting element being configured and arranged in such a way that it can be displaced counter to the prestress into its second functional position by way of a pump pressure which is generated in the pressure region during operation of the pump. The pump is distinguished by the fact that the cold starting element is arranged in its second functional position at least in regions with a relief face which faces away from the pressure region in a relief receptacle in such a way that the relief face is loaded during operation of the pump with a pressure which is smaller than a system pressure in the outflow region.
Patent CA-2856481-A1 (CA)
Title: Procede et dispositif de dosage controle de compositions de traitement dans des machines a laver
Inventor: MCKENNA SHAUNA
IPC: A47L15/44
Filed: 2012-11-22
Abstract: La présente invention concerne un procédé de distribution d'une pluralité de compositions dans une machine à laver automatique à plusieurs étages, ainsi qu'un dispositif de distribution comprenant un réservoir associé pour la collecte de liqueur de lavage et au moins deux chambres contenant une composition de traitement. Lesdites chambres sont activées en réponse à une entrée d'un capteur.
Patent CA-2858440-A1 (CA)
Title: Method for determining the impact point of a projectile fired at a target above sea surface, and radar system implementing such method
Inventor: VAN OMMEREN MARINUS JOSEPHUS SERVATIUS
IPC: G01S13/72
Filed: 2012-11-30
Abstract: There is disclosed a method for determining the impact point of a projectile fired at a target (15) tracked by use of a radar antenna (11) through a dedicated antenna beam, the method being characterized in that it comprises at least a step of measuring the range and bearing of the projectile based upon the use of said radar antenna (11) and said dedicated antenna beam, a step of Doppler filtering distinguishing the projectile measurements from the tracked target (15) and sea clutter measurements, and a step of determining the projectile trajectory (131) from a plurality of range and bearing measurements performed at successive instants of time (t i), and a step of determining the impact point of the determined projectile based upon the projectile trajectory (131). The current invention can be applied to splash spot location prediction and miss distance indication.
Patent CA-2862590-A1 (CA)
Title: Funnel component and manufacturing method for manufacturing packaging container using funnel component
Inventor: SAITO TAKESHI
IPC: B31B50/64
Filed: 2012-12-28
Abstract: Provided are a funnel part and a method for manufacturing a packaging container in which the funnel part is used. The funnel part is manufactured using: a step for curving a blank to form a tapered first intermediate body; a step for folding back and welding the opening on the narrow-opening side of the first intermediate body to form a second intermediate body; a step for folding back the opening on the wide-opening side of the second intermediate body to the outer side to form a third intermediate body having a side-wall portion; and a step for drawing the third intermediate body and forming a cylindrical exhaust part constituting the narrow-opening side opening, a first tapered taper part connected to the exhaust part, and a second tapered taper part having a taper angle smaller than that of the first taper part. The packaging container is manufactured using: a step for forming a cup-shaped container body having a cylindrical side wall, a bottom, and an open end; and a step for orienting the wide-opening side opening of the funnel part toward the bottom of the container body, inserting the funnel part from through the open end of the container body toward the interior, and joining the outer surface of the side wall to the inner circumferential surface of the funnel part.
Patent CA-2865511-A1 (CA)
Title: 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
Inventor: ASHWORTH ALAN
IPC: A61K31/4725
Filed: 2013-03-07
Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 3-aryl-5-substituted- 2H-isoquinolin-1-one compounds that, inter alia, inhibit PARP (e.g., PARP1, TNKS1, TNKS2, etc.) and/or Wnt signalling. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit PARP (e.g., PARP1, TNKS1, TNKS2, etc.); to inhibit Wnt signalling; to treat disorders that are ameliorated by the inhibition of PARP (e.g., PARP1, TNKS1, TNKS2, etc.); to treat disorders that are ameliorated by the inhibition of Wnt signalling; to treat proliferative conditions such as cancer, etc.
Patent CA-2866592-A1 (CA)
Inventor: TSUDA AKINORI
IPC: G01N27/90
Filed: 2013-02-15
Abstract: An eddy-current inspection method comprises: synchronization steps (S3, S4) of synchronizing the phase of exciting voltage with the phase of driving voltage, the exciting voltage being applied by a coil driving means to an exciting coil for generating eddy current in a body to be inspected, the driving voltage having a higher frequency than the exciting voltage and being applied by an element driving means to a magnetic impedance effect element for detecting a magnetic field change occurring in the exciting coil; and a magnetic field detection step (S5) of detecting, using the magnetic impedance effect element, the magnetic field change occurring in the exciting coil due to eddy current occurring in the body to be inspected.
Patent CA-2867065-A1 (CA)
Inventor: D AMICO PETER
IPC: B09B3/00
Filed: 2013-03-14
Abstract: A method for treating powdered activated carbon (PAC) and/or coal combustion residues (CCRs) by heating at least one of a spent PAC and/or a CCR to separate at least one heavy metal from the at least one of the spent PAC and/or the CCR to create a clean stream and a heavy metal stream, combining the heavy metal stream with a water soluble alkaline-earth metal sulfide to create a combined stream, and removing at least a portion of the at least one heavy metal from the combined stream. The heating may further include heating the at least one of the spent PAC and/or the CCR in an inert atmosphere. Further, the combining may include combining the heavy metal stream with the water soluble alkaline-earth metal sulfide and a catalyst and/or a surfactant or hyperdispersant.
Patent CA-2867714-A1 (CA)
Inventor: MIRACLE GREGORY SCOT
IPC: C11D3/00
Filed: 2013-03-19
Abstract: This application relates to laundry care compositions comprising carboxylate fabric shading dyes and methods of treating a textile comprising such laundry care compositions.
Patent CA-2868770-A1 (CA)
Inventor: SCHUBERT BERND
IPC: H02G1/14
Filed: 2013-03-01
Abstract: The present invention provides a non-return valve for a resin injection system, especially for use in electrical cable joints, comprising: a valve housing which includes an outlet for a fluid flowing through the valve; and a valve body which is held by the valve housing and is freely movable between a closed position, in which the outlet is substantially sealed or closed to fluid flow by the valve body, and an open position, in which the outlet is substantially open to fluid flow. Thus, with the present invention, the valve body can be loosely held by the valve housing and the valve need not include any spring means to bias the valve body to the closed position. The invention also provides a resin injection system for sealing a localised breach in an object, such as an electrical cable joint.
Patent CA-2870814-A1 (CA)
Title: Glazing system and methods
Inventor: TURNER JEREMY
IPC: B60J1/00
Filed: 2013-04-22
Abstract: Disclosed is a glazing system for a passenger service vehicle, as well as a passenger service vehicle comprising such a glazing system. The system generally comprises glazing frames that are attached to a passenger service vehicle, which have glazing mounts extending inwardly along some or all of the frames. The mounts are configured to associate a glazing panel with the frame. Further, there is disclosed a removable retainer configured to engage with the frame, and to retain a glazing panel against the glazing mount. In some examples, the frame comprises a frame retainer and the removable retainer is configured to engage between the frame retainer and a glazing panel in an interference manner in order to retain, or urge and retain, a glazing panel against the glazing mount. During repair, or maintenance, the retainer can be removed to allow for ease of replacement or repair of the glazing panel.
Patent CA-2873930-A1 (CA)
Title: Insulating frame with corner expansion joints for electrolysis cells
Inventor: HOORMANN DIRK
IPC: C25B9/19
Filed: 2013-07-12
Abstract: An insulating frame for electrolysis cells is proposed, which has a geometric form with corners, said insulating frame being of a flat design and having an anode and a cathode side as well as an outer and inner end face, the insulating frame being characterised in that it is has an edge area directly adjoining the inner end face, characterised in that in the area of the corners the edge area has corner expansion joints in the form of cut-outs.
Patent CA-2874311-A1 (CA)
Inventor: PERETOLCHIN MAXIM
IPC: C10G33/04
Filed: 2013-04-30
Abstract: Use of a reaction product of saturated or unsaturated aliphatic mono- or polycarboxylic acids with aliphatic polyamines for improving or boosting the separation of water from fuel oils which comprise additives with detergent action. A Fuel additive concentrate comprising the said reaction product, certain additives with detergent action and optionally dehazers, cetane number improvers and solvents or diluents.
Patent CA-2875019-A1 (CA)
Title: High intensity led illumination device
Inventor: CASPER JOSEPH R
IPC: F21W107/10
Filed: 2014-12-17
Abstract: A lighting device includes a light emitting diode (LED) structure having LEDs, a housing, and a power supply. The housing receives and secures the LED structure, and includes a body portion that comprises a heat sink for the LED structure, and a shroud that at least partially shields the LED structure. The heat sink comprises various fins that extend away from the LED module in a direction that is perpendicular to a width of the LED structure.
Patent CA-2875589-A1 (CA)
Inventor: BOHLIN MARTIN HANS
IPC: A61K31/4439
Filed: 2013-06-20
Abstract: A camsylate salt of (1r,1 'R,4R)- 4-methoxy-5"-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-inden-1'2'-imidazole]-4"-amine, pharmaceutical compositions containing the salt and therapeutic uses of the salt for treating ?ß-related pathologies such as Alzheimer's Disease, Down's syndrome, ß-amyloid angiopathy and conditions such as dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
Patent CA-2878297-A1 (CA)
Inventor: NADON GILLES
IPC: B66F9/00
Filed: 2015-01-20
Abstract: L'invention relève du domaine des véhicules outils destinés aux services de voirie ainsi qu'aux entreprises de construction et d'entretien des routes lors de travaux de réfection de surfaces de pavage ou autres travaux d'entretien du réseau routier. A l'heure actuelle, les opérations de déposition et de ramassage de barils orange, servant à baliser les limites des zones de travail, se font manuellement par des jeunes gens qui risquent leur vie, exposés à la circulation automobile, parfois rapide. La solution proposée permet d'effectuer mécaniquement ces opérations d'une manière sécuritaire, rapide et efficace. Le mécanisme comprend une structure triangulaire à laquelle sont fixés des supports verticaux supportant des cerceaux pour ranger les barils. La déposition et le ramassage des barils sont régis par un ensemble d'opérations mécaniques.
Patent CA-2880773-A1 (CA)
Inventor: PIETRELLA DIEGO
IPC: F21V21/26
Filed: 2013-07-26
Abstract: A lamp (100) comprising a base PCB (1), at least one support PCB (2) connected to the base PCB, a lighting assembly (4) connected to the support PCB (2) and at least one light source and power supply connected to conductive tracks of the base PCB (1).
Patent CA-2882438-A1 (CA)
Inventor: BARUTO ALESSANDRO
IPC: C07D417/12
Filed: 2015-02-19
Abstract: The present invention relates to a process for the synthesis of dasatinib and to intermediates useful for its preparation.
Patent CA-2884746-A1 (CA)
Inventor: YOUNES MAGDY
IPC: G06F19/00
Filed: 2013-09-12
Abstract: Method and software are provided to format a probability index that reflects where an electroencephalogram (EEG) pattern lies within the spectrum of wakefulness to deep sleep, which employs a computer/microprocessor that performs frequency domain analysis of one or more discrete sections (Bins) of the EEG to determine the EEG power at specified frequencies, optionally calculates the total power over specified frequency ranges, assigns a rank to the power at each frequency, or frequency range, assigns a code to the Bin that reflects the ranking of the different frequencies or frequency ranges, and determines an index that reflects where said EEG pattern within said Bin(s) lies within the spectrum of wakefulness to deep sleep by use of a reference source, such as a look-up table or other suitable decoding instrument. The reference source is obtained by calculating the probability of Bins with different codes occurring in epochs scored as awake or asleep in reference files scored by one or more expert technologists or by an automatic scoring software.
Patent CA-2885419-A1 (CA)
Inventor: PETERSON DALE R
IPC: A61K35/44
Filed: 2013-09-17
Abstract: The present invention provides novel compositions comprising multipotent ceils or microvascular tissue, wherein the cells or tissue has been sterilized and/or treated to inactivated virases, and related methods of using these compositions to treat or prevent tissue injury or disease in an allogeneic subject.
Patent CA-2887354-A1 (CA)
Title: Process for preparing an inhibited starch
Inventor: SANTHANAM BALAJI
IPC: A23L5/49
Filed: 2013-10-02
Abstract: The present invention provides a process for preparing an inhibited starch comprising, in order: a) extracting starch from a native source and partially refining to provide a partially refined starch having a residual protein content on a dry starch basis of more than 0.4 % by weight and less than 8.0 % by weight; b) treating said partially refined starch with a bleaching agent to provide an inhibited starch; and c) recovering said inhibited starch.
Patent CA-2890758-A1 (CA)
Inventor: BATEMAN RANDALL
IPC: G01N33/53
Filed: 2013-11-20
Abstract: A method of diagnosing an amyloid pathology in the central nervous system of a patient using measurements of enrichment kinetics of at least one amyloid-ß isoform is provided. In addition, a model to predict enrichment kinetics of at least one amyloid-ß isoform, methods of calibrating the model, and methods of using the model to diagnosing an amyloid pathology in the central nervous system of a patient are provided.
Patent CA-2892728-A1 (CA)
Inventor: LI YAN
IPC: C12Q1/68
Filed: 2013-12-02
Abstract: New mutations were found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutations, methods of prognosis and methods of predicting response to treatment based on the presence of absence of the mutations 2240_2264>CGAAAGA or 2252_2277>GAGAAGCC in SEQ ID NO: 1.
Patent CA-2896267-A1 (CA)
Title: Endoluminal introducer
Inventor: LEEUW CHRISTOPHER
IPC: A61B1/31
Filed: 2013-12-24
Abstract: An introducer for use during endoscopic procedures provides insufflation, washing, and aspiration functions, and provides for the protection of the endoluminal surface during laparoscopic examination of an anastomosis or suture line following low anterior resection of the bowel. The introducer may be designed for the insertion of an endoscope capable of white light and/or near infra-red fluorescence imaging info the rectum for analysis of an anastomosis following low anterior resection of the bowel.
Patent CA-2901007-A1 (CA)
Inventor: WU YILIANG
IPC: H05K3/28
Filed: 2015-08-17
Abstract: A method of digitally printing a solder mask. The method includes providing a solder mask ink composition including: 1) a resin and 2) a solvent in an amount of at least 20 % by weight relative to the total weight of the solder mask ink composition. The composition has a viscosity that is less than 1000 cps at a shear rate of 10 s-1 and a temperature of 25° C. An aerosol stream is generated from the solder mask ink composition with a pneumatic atomizer using an atomization gas. The aerosol stream is directed through a nozzle and focused using a sheath gas onto a substrate while changing the position of the nozzle with respect to the substrate to selectively deposit a solder mask pattern. The solder mask pattern is cured.