baber/WOPTO huggingface dataset:
Patent EP-3813840-A1 (EP)
Inventor: EBETINO FRANK HALLOCK
IPC: A61P31/04
Filed: 2019-06-25
Abstract: Described herein are bisphosphonate oxazolidinone compounds, and conjugates and pharmaceutical formulations thereof, that can include a bisphosphonate and an oxazolidinone (or an oxazolidinone antimicrobial or antibiotic agent, substituent or derivative thereof), where the oxazolidinone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate oxazolidinone compounds, conjugates and pharmaceutical formulations thereof. Also provided herein are methods of use of the compounds, conjugates and formulations for treating a bone disease or for use in preparing a formulation for the treatment a bone disease.
Patent EP-3810132-A1 (EP)
Inventor: GRAY NATHANAEL S
IPC: C07D231/38
Filed: 2019-06-24
Abstract: Provided herein are compounds of Formula (I´) or (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing diseases ( e.g ., proliferative diseases ( e.g. , cancers ( e.g. , carcinoma); lung cancer, breast cancer, liver cancer, pancreatic cancer, gastric cancer, ovarian cancer, colon cancer, colorectal cancer)), metabolic disorders ( e.g. , diabetes), autoimmune diseases, and neurological diseases ( e.g. , Alzheimer's disease, gliosis, spinal cord injury)) in a subject, as well as for male contraception ( e.g. , reducing or inhibiting spermatogenesis, or reducing the rate of male fertility in a healthy fertile male subject). Provided are methods of inhibiting a CDK ( e.g. , CDK14, CDK15, CDK16, CDK17, CDK18) in a subject.
Patent EP-3897587-A1 (EP)
Inventor: NOGUEIRAS NIETO LUIS
IPC: A61P35/00
Filed: 2019-12-20
Abstract: The present invention relates to a tablet composition comprising ibrutinib and one or more pharmaceutically acceptable excipients, characterized in that: • Ibrutinib is form C, having characteristic peaks in the X-ray powder diffraction pattern at the following 2 theta (±0.2) angles: 6.9º, 18.2º, 19.2º, 19.6º and 23.0º, measured using a Cu Kα radiation; and • Ibrutinib form C is present in an amount from 60 to 80% w/w relative to the total weight of the tablet; and • The composition is free of surfactant; and • The composition exhibits a dissolution rate of at least 65% in 20 minutes when tested in 900 ml 0.01 N hydrochloric acid pH 2.0 (+1% Tween 20) at 37ºC, 75 rpm and/or in 900 ml phosphate buffer pH 6.8 (+3% Tween 20) at 37ºC, 75 rpm in a USP apparatus II. The invention further relates to the use of said composition as a medicament, particularly in the treatment of chronic lymphocytic leukaemia (CLL), mantle cell lymphoma (MCL) and Waldenstrӧm's macroglobulinaemia (WM).
Patent EP-3898867-A1 (EP)
Inventor: PILZ DAVID
IPC: C08F220/18
Filed: 2019-12-17
Abstract: Es soll eine gut hautverträgliche, gut haftende, leicht und schmerzarm von der Haut ablösbare und atmungsaktive Klebmasse zur Verfügung gestellt werden. Dies gelingt mit einer Klebmasse zur Verklebung auf der Haut, die a) mindestens ein Copolymer, das sich auf eine Monomerenzusammensetzung, umfassend - mindestens einen (Meth)acrylsäurealkylester, - mindestens ein ethylenisch ungesättigtes Monomer, enthaltend mindestens eine Carboxygruppe, und - mindestens einen Photoinitiator zurückführen lässt; und b) mindestens einen Carbonsäureester, enthaltend mindestens 10 C-Atome, enthält. Gegenstand der Erfindung sind auch eine Auflage zur Verklebung auf der Haut und eine auf der Haut tragbare medizinische Vorrichtung, die jeweils eine erfindungsgemäße Klebmasse umfassen, sowie die Verwendung einer erfindungsgemäßen Klebmasse zur Herstellung von Verklebungen auf der Haut.
Patent EP-3894877-A1 (EP)
Inventor: CROUZEVIALLE BRUNO
IPC: G01R31/396
Filed: 2019-12-12
Abstract: The present description concerns a method for determining the state of health of the cells (Ci) of a battery, comprising: a) during a discharge phase (101) of the battery, measuring the voltage Ui at the terminals of each cell (Ci); b) when a first cell (Ci_lim) reaches a predefined end-of-discharge condition, interrupting (102) the discharge and storing the end-of-discharge voltage Ui of each cell; c) determining (103) a value QCi_lim representative of the capacity of the first cell; d) calculating (104), for each other cell, an interpolation coefficient C_interp_i; and e) determining (105), for each other cell, from the value QCi_lim and the interpolation coefficient C_interp_i calculated for the cell, a value QCi representative of the capacity of the cell.
Patent EP-3833285-A1 (EP)
Title: Tissue treatment with sensitizer and light and/or sound
Inventor: ELLIASON BRADEN
IPC: A61B18/12
Filed: 2019-08-08
Abstract: A catheter is disclosed that may be used in a minimally invasive internal treatment (e.g., sonodynamic therapy). The catheter can include a housing, a portion of which may be positioned in contact with internal tissue of a patient during a minimally invasive sonodynamic or photo- sonodynamic therapy procedure. The catheter may include multiple electrically independent ultrasound transducers. The ultrasound transducers can be configured to emit ultrasound energy into the internal tissue of the patient. The ultrasound energy that is emitted from the catheter may reach a target tissue depth at a relatively low temporal average intensity (e.g., less than 50 W/cm2). Such ultrasound energy may activate the sensitizer.
Patent EP-3794467-A1 (EP)
Inventor: AHER ANKUR ANIL
IPC: G06F16/9538
Filed: 2019-11-27
Abstract: Systems and methods are described for responding to a search query with a contextually relevant voice output. An illustrative method receives a search query, determines an answer to the search query, identifies a media content reference included in the search query, determines, based on the media content reference, a personality associated with the media content reference, identifies a voice profile of the personality, and generates audio output using the voice profile of the personality, the audio output including the answer to the search query.
Patent EP-3850887-A1 (EP)
Inventor: SHEN JIA
IPC: H04W28/20
Filed: 2019-09-12
Abstract: L'invention concerne un procédé et un appareil de transmission d'informations de liaison latérale, ainsi qu'un dispositif terminal et un dispositif réseau. Dans le procédé, un premier UE (équipement utilisateur) reçoit des premières informations de configuration en provenance d'une station de base, les premières informations de configuration servant à configurer le premier UE avec au moins une première partie de bande passante (BWP) pour une réception de liaison latérale ; et l'UE reçoit des informations de liaison latérale en provenance d'un second UE sur la première BWP.
Patent EP-3846366-A1 (EP)
Inventor: CHANG JUNREN
IPC: H04L1/00
Filed: 2019-09-10
Abstract: Embodiments of this application provide a communication method and a device. The communication method includes: when a network device meets an enabling condition, sending, by the network device, configuration information to a terminal, where the configuration information includes at least one of a type of indication information, a form of the indication information, or a receiving location of the indication information; and sending the indication information to the terminal, where the indication information is used to indicate the terminal whether to monitor a physical downlink control channel PDCCH, or indicate the terminal to monitor a PDCCH, or indicate the terminal not to monitor a PDCCH; or the indication information is used to indicate the terminal whether to receive a physical downlink shared channel PDSCH, or indicate the terminal to receive a PDSCH, or indicate the terminal not to receive a PDSCH. This improves flexibility of using the indication information (for example, a UPSS) by the terminal.
Patent EP-3887470-A1 (EP)
Inventor: FEDURCO MILAN
IPC: C09J179/04
Filed: 2019-11-27
Abstract: The invention relates to a multi-composite material (R1, R2) comprising at least one monofilament (10) made of a glass-resin composite which comprises glass filaments (101) embedded into a thermoset polyester resin (102), characterised in that said monofilament is coated with at least one layer (12) of benzoxazine; to the use of such a material as reinforcement in finished articles or semi-finished products made of rubber; and to finished articles or semi-finished products made of rubber such as vehicle tyres which are reinforced with such a material.
Patent EP-3863465-A1 (EP)
Inventor: LAFAUCI MARIAGRAZIA
IPC: A45D8/22
Filed: 2019-10-11
Abstract: A hair clip apparatus includes a tongue, a clasp and a plurality of hair engaging teeth. The clasp cooperates with the tongue to retain the hair in a desired styling effect. The hair engaging teeth are spaced from the clasp and the tongue to engage hair surrounding the clasp and the tongue. The hair clip apparatus is retained in the volume of hair by trapping the hair between the clasp and the tongue, and also via the hair engaging teeth. The hair engaging teeth also are arranged to retain and secure hair between adjacent teeth, and also trap hair between the inner surfaces of the teeth and the base and/or tongue.
Patent EP-3870046-A1 (EP)
Inventor: COLES SCOTT
IPC: A61B3/10
Filed: 2019-10-23
Abstract: Blepharometric data (data describing eyelid position as a function of time) is recorded and processed for the purposes of predicting a future risk and/or current occurrence of neurological events such as seizures. For example, in one embodiment blepharometric data is recorded via infrared reflectance oculography spectacles, and processed in real time thereby to extract a set of blepharometric artefacts. Where those artefacts indicate prolonged spiking in blink calmness (for example based on spiking in negative inter-event duration, or negative IED), an alert is able to be generated thereby to indicate that the subject is at risk of a seizure in a proximal time period. This provides an opportunity to implement mitigation measures, for example to reduce the likelihood of the seizure manifesting, and/or to mitigate harm should the seizure occur.
Patent EP-3873606-A1 (EP)
Inventor: DAVIDSON JAN KENNETH
IPC: A61P31/00
Filed: 2019-10-29
Abstract: The present invention is directed to a method of treating a hematologic malignancy such as acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS), including hematologic malignancies that are refractive to chemotherapeutic and/or hypomethylating agents. The method concerns administering a CD123 x CDS bispecific binding molecule to a patient in an amount effective to stimulate the killing of cells of said hematologic malignancy in said patient. The present invention is additionally directed to the embodiment of such method in which a cellular sample from the patient evidences an expression of one or more target genes that is increased relative to a baseline level of expression of such genes, for example, a baseline level of expression of such genes in a reference population of individuals who are suffering from the hematologic malignancy, or with respect to the level of expression of a reference gene.
Patent EP-3876668-A1 (EP)
Inventor: SHIMAO TSUBASA
IPC: F23Q7/22
Filed: 2019-10-29
Abstract: A heater of the disclosure includes: an insulating base including a rod-shaped portion; a heat generating resistor located inside the insulating base; a fixing member which is a cylindrical member, inside the fixing member the insulating base being inserted; and a spacer which is a belt-shaped member, the spacer being located between the rod-shaped portion and the fixing member and surrounding the rod-shaped portion in a circumferential direction. The spacer includes one end and another end which face each other.
Patent EP-3873505-A1 (EP)
Inventor: WONG PHILIP C
IPC: C07K19/00
Filed: 2019-11-04
Abstract: L'invention concerne un adénovirus ou un vecteur adénoviral qui comprend une séquence nucléotidique non native pouvant exprimer une protéine chimérique comprenant un domaine de liaison de nucléotide N-terminal de la protéine de liaison à l'ADN d'élément de réponse de transactivation (TDP-43), un domaine C-terminal dérivé d'un répresseur d'épissage, et un élément autorégulateur. L'invention concerne également des procédés d'utilisation de l'adénovirus ou du vecteur adénoviral pour traiter des maladies dégénératives telles que la myocytose du corps d'inclusion, la sclérose latérale amyotrophique et la démence frontotemporale.
Patent EP-3828381-A1 (EP)
Inventor: UETAKE MASAAKI
IPC: E21C41/16
Filed: 2019-10-30
Abstract: A mining system (100) includes: a first tunnel that reaches a dump site and includes a first road surface (13); a second tunnel that crosses the first tunnel, reaches a mining site, and includes a second road surface (22) positioned above the first road surface (13); a frame (30) that includes a lower surface (31a) provided above the first road surface (13) of the first tunnel and forming a transport passage (P) between the first road surface (13) and the lower surface (31a) and an upper surface (31b) forming a work road surface (S), on which a loading machine operates, together with the second road surface (22); and a moving vehicle that is capable of traveling on the first road surface (13) and is capable of passing through the transport passage (P).
Patent EP-3702403-A1 (EP)
Inventor: KOO KICHUL
IPC: C08K5/544
Filed: 2019-07-24
Abstract: [Summary]The present invention relates to a crosslinking agent compound in which a terminal crosslinkable functional group is capped with a silane-based protecting group, a photosensitive composition including the same, and a photosensitive material using the same.
Patent EP-3971236-A1 (EP)
Inventor: YOO MYUNG-IK
IPC: C08L27/06
Filed: 2019-10-18
Abstract: Provided are a plasticizer composition having excellent low-temperature characteristics and capable of improving migration of a plasticizer, and a vinyl chloride-based resin composition including the same.
Patent EP-3904285-A1 (EP)
Inventor: FUJIMORI TOSHIHIKO
IPC: C30B29/62
Filed: 2019-12-26
Abstract: A method for manufacturing a carbon nanotube includes: a growing step of growing a carbon nanotube from a catalyst particle by supplying a carbon-containing gas to the catalyst particle in a suspended state; and a drawing step of drawing the carbon nanotube by applying a tensile force to the carbon nanotube in a suspended state.
Patent EP-3918310-A1 (EP)
Inventor: COOPER JEREMY RYAN
IPC: G01N21/64
Filed: 2019-07-17
Abstract: La présente invention porte d'une manière générale sur la détection de multiples biomarqueurs situés sur un échantillon, ou à l'intérieur de celui-ci, mais plus particulièrement, sur la détection de fractions de détection individuelles à l'intérieur d'une pluralité de fractions de détection.
Patent EP-3796266-A1 (EP)
Title: Method and apparatus for reconstructing point cloud model, and system
Inventor: Wang hai feng
IPC: G06T17/00
Filed: 2019-08-01
Abstract: The present invention provides a point cloud model reconstruction method, apparatus, and system. The method includes the following steps: randomly selecting four non-coplanar reconstruction points in the point cloud model; keeping iteratively selecting other reconstruction points successively until a reconstruction condition is met, and reconstructing the point cloud model based on all reconstruction points, where a reduction degree of the reconstructed point cloud model is:      Reward   =   −   k   ⋅     PointNum   −   4     +   g   ⋅   VolRate   ,        where PointNum represents a number of current selected reconstruction points, VolRate represents a volume ratio of a volume of a solid shape formed by all of the current reconstruction points to an original volume of the point cloud model, k represents a proportion of the number of the selected points in the reduction degree, and g represents a proportion of the volume ratio in the reduction degree. The reconstruction method further includes the following step: adjusting a ratio of g to k based on user requirements to adjust the reconstruction condition. The point cloud model reconstruction mechanism provided in the present invention can improve resolution of a reconstructed point cloud model and control quality of points in the reconstructed point cloud model.
Patent EP-3937292-A1 (EP)
Inventor: CHEN SHEBIAO
IPC: H02J7/00
Filed: 2019-03-22
Abstract: The present disclosures a charging and discharging control method, and a device to be charged. The charging and discharging control method can be applied to a device to be charged. Said device comprises: a first battery unit and a second battery unit which are connected in series, and a balance module; the second battery unit supplies power to said device. Said method comprises: when the voltage of a second battery unit is equal to or less than a first preset voltage threshold, transferring power in a first battery unit to the second battery unit by means of a balancing module, such that the voltage of the second battery unit is greater than the first voltage threshold.
Patent EP-3950358-A1 (EP)
Title: Method of driving inkjet head, and inkjet recording device
Inventor: LI XINZE
IPC: B41J2/01
Filed: 2019-03-29
Abstract: Provided are a method of driving an inkjet head, and an inkjet recording device, which make it possible to effectively curb a decrease in image quality. This driving method is for an inkjet head that comprises a nozzle and a pressure generation unit for, in accordance with application of a drive signal, applying a change in pressure to ink in a pressure chamber that communicates with the nozzle so as to cause the ink to be discharged from the nozzle. The inkjet head forms a single pixel by causing a plurality of droplets of ink, discharged from the nozzle in accordance with a series of applications of drive signals, to come into contact with a recording medium. The method involves: applying, to the pressure generation unit, a series of drive signals containing a first drive signal having a first voltage amplitude and a second drive signal having a second voltage amplitude greater than the first voltage amplitude, the final drive signal in the series of drive signals being the second drive signal; and establishing the first voltage amplitude and the second voltage amplitude such that a ratio Va/Vb, where Va is the first voltage amplitude and Vb is the second voltage amplitude, will be a value corresponding to the specific gravity of the ink that is discharged from the nozzle.
Patent EP-3959914-A1 (EP)
Inventor: LONG HONGXIA
IPC: H04W12/08
Filed: 2019-11-08
Abstract: Selon des modes de réalisation, la présente invention concerne des procédés et des appareils pour la découverte de services.
Le procédé consiste à déterminer d'initier une authentification d'un équipement utilisateur (UE) ; et à envoyer un message de requête d'authentification comprenant une identité cryptée ou non cryptée d'un abonné de l'UE, un nom de réseau de desserte et des informations de routage d'un nœud de gestion de données à un serveur d'authentification.
Patent EP-3970135-A1 (EP)
Title: Pixel circuit and pixel control method
Inventor: TAKATORI KENICHI
IPC: G09G3/32
Filed: 2019-05-31
Abstract: Provided are a pixel circuit (5,6) and a pixel control method capable of quickly controlling pixels with a simpler configuration of a combination of a photosensor (502,602) and a pixel unit drive circuit (501,601). The pixel unit drive circuit(501,601) includes: a switching transistor (T52) for switching a data signal to be applied to a data line; a driving transistor (T53) for supplying a drive current to an organic light emitting diode (OLED) according to a charge voltage corresponding to the data signal; a compensation transistor (T55) for compensating for a threshold voltage of the driving transistor (T53); and a photosensor (502,602) having a terminal to which a bias voltage(VPD) is applied, wherein the switching transisto r(T52) is a dual gate transistor having a first gate connected to another terminal of the photosensor(502,602), and a second gate connected to a gate of the compensation transistor (T55).
Patent EP-3995874-A1 (EP)
Inventor: ZHU HU
IPC: G02B6/42
Filed: 2019-12-13
Abstract: An optical-path-displacement-compensation-based emission optical power stabilization assembly, comprising: a laser, a lens, and an optical fiber coupling port disposed on a first substrate and a second substrate according to a preset arrangement scheme, wherein an expansion coefficient of the second substrate is larger than that of the first substrate, and the preset arrangement scheme enables initial distances between the laser and the lens, between the lens and the optical fiber coupling port, and/or between the laser and the optical fiber coupling port to differ from respective optical coupling distances from an optical coupling point by a preset value, thereby ensuring that a coupling loss on an optical path changes along with the temperature, forming a complementary effect with respect to an optical power-temperature curve of the laser, which reduces a temperature-caused fluctuation of the emission optical power of an optical assembly.
Patent EP-3792465-A1 (EP)
Inventor: DUROCHER ERIC
IPC: F02C7/36
Filed: 2017-08-15
Abstract: A multi-spool gas turbine engine (10) comprises a low pressure (LP) spool (20) and a high pressure (HP) spool (40) independently rotatable about a central axis (17) extending through an accessory gear box (AGB) (50). The LP spool (20) has an LP compressor (22), which is axially positioned between the HP compressor (42) of the HP spool (40) and the AGB (50). A tower shaft (51) drivingly connects the HP spool (40) to the AGB (50).
Patent EP-3689160-A1 (EP)
Inventor: ZHOU WEIDONG
IPC: A24F40/40
Filed: 2020-01-21
Abstract: The present invention relates to an electronic atomizing device comprising an atomizing assembly and a puff sensor electrically connected with the atomizing assembly; an air passage fluidly connected to the atomizing assembly and a starting passage fluidly connected between the airflow passage and the puff sensor are defined in the electronic atomizing device; the starting passage defines a receiving groove for receiving a condensed aerosol. The condensed aerosol is received by the receiving groove when flowing into the starting passage, and is prevented from flowing into the main body to cause damage to elements such as the power supply, the puff sensor and a PCB therein, thereby extending the service life of the main body.
Patent EP-3702707-A1 (EP)
Inventor: BERTOLINI NILTON
IPC: F25D23/12
Filed: 2020-01-22
Abstract: A refrigerator including a fresh food compartment; at least one shelf disposed in the fresh food compartment, the at least one shelf being supported by at least one shelf support bracket; and a water dispenser integrated with the at least one support bracket and accessible from the fresh food compartment.
Patent EP-3702595-A1 (EP)
Inventor: SHIRAHASHI NAOTOSHI
IPC: F02D41/00
Filed: 2020-01-23
Abstract: In a compression-ignition engine having a two-stage cavity, the distribution ratio between fuel for an upper cavity and fuel for a lower cavity is maintained even when the operational state of the engine changes. A piston 5 of the compression-ignition engine includes a lower cavity (lower cavity portion 51), an upper cavity (upper cavity portion 52), and a lip portion 53 between the lower cavity and the upper cavity. A control unit (ECU 10) causes a main injection and at least one pilot injection to be executed when the engine 1 operates in a first state and a second state in which the speed is higher than the speed in the first state. The fuel spray is distributed to the lower cavity and the upper cavity. The control unit increases an injection amount per pilot injection when the engine operates in the second state than when the engine operates in the first state.