baber/WOPTO huggingface dataset:
Patent CA-2182581-A1 (CA)
Title: Enantiomerically pure(-)-liarozole
IPC: C07D521/00
Filed: 1995-02-10
Abstract: This invention relates to the novel enantiomer-ically pure laevorotatory isomer of liarozole of for-mula (I) and the pharmaceutically acceptable acid addition salt forms thereof. These compounds are particularly useful in treating disorders which are characterized by an increased proliferation and or abnormal differentiation of normal, preneoplastic or neoplastic epithelial cells. The compounds of for-mula (I) are particularly useful in the field of oncology. Also disclosed are compositions containing said novel compounds, methods of preparing said novel compounds as well as methods of using the mentioned compounds to treat the mentioned disorders.
Patent CA-2182822-A1 (CA)
Inventor: REITERMAN LEE
IPC: B23C5/10
Filed: 1996-08-07
Abstract: An polygonal indexable  insert for use in  periphery milling cutters. The  insert  is  a  positive insert  having  compound clearance  faces comprised of  a curve primary  clearance surface adjacent  the cutting  edge  and  a  planar  secondary  clearance surface adjacent  the clearance edge  of the insert.   The curved primary  clearance  surface  imparts  improved  strength  to  the cutting edge of the insert.
Patent CA-2185093-A1 (CA)
Title: System for performing a cardiac procedure
Inventor: MACHOLD TIMOTHY R
IPC: A61F2/958
Filed: 1995-03-10
Abstract: A system for accessing a patient's cardiac anatomy which includes an occlusion catheter (10) with a first expandable member (11) or balloon on a distal extremity of the catheter which when expanded within the patient's ascending aorta separates the heart and coronary blood vessels from the rest of the patient's arterial system, and a second expandable member (15), distal to the first, which when expanded will be seated within the left ventricle.  A cardiopulmonary bypass system (18) is connected to a major vein, e.g., femoral (20), to withdraw blood, remove carbon dioxide, oxygenate the withdrawn blood, and then return the oxygenated blood to the patient's arterial system through a major artery (22). Preferably, the heart muscle or myocardium is paralyzed by the antegrade and/or retrograde delivery of a liquid containig cardioplegic material to the myocardium through patient's coronary arteries or coronary sinus. The cardiac accessing system is suitable for a wide variety of cardiac procedures including opened and closed chest procedures.
Patent CA-2186838-A1 (CA)
Inventor: WESTERGAARD DAVID JEFFREY
IPC: H04M3/48
Filed: 1996-09-30
Abstract: An apparatus for muting communications subscriber equipment connected to a communications line includes a monitoring circuit for monitoring electrical conditions of the communications line, when the subscriber equipment is connected thereto. A disconnection circuit is provided for disconnecting the subscriber equipment from the communications line and a termination circuit is provided for terminating the communications line with a dummy termination when the subscriber equipment is disconnected, such that, the communications line appears to be terminated by the subscriber equipment. When the subscriber equipment is disconnected from the communications line a power supply circuit provides power to the subscriber equipment with the same electrical conditions as determined by the monitoring circuit prior to disconnecting the subscriber equipment.
Patent CA-2187532-A1 (CA)
Title: Door Having Snap-On Facades
Inventor: LEWIS RICHARD J
IPC: E06B3/48
Filed: 1995-04-21
Abstract: A door (10) whose outer appearance may be readily altered has at least one panel (12) with a back side (22) and a front face (23) including a plurality of horizontal locking slots (32, 34, 36) formed thereacross and interchangeable facades (14, 16) having a decorative front side (50) and a back side (52) with integrally formed, backwardly projecting clips (54, 56) adapted to releasably interlock with the slots.  The panel includes end caps (38) adapted to receive the facades (14, 16) thereunder, with the facades being movable in the slots (32, 34, 36), to accommodate expansion and contraction of the facades and door.
Patent CA-2191534-A1 (CA)
Title: Deicer
Inventor: AMAKO KIYOO
IPC: B64F5/00
Filed: 1996-11-28
Abstract: A deicer includes a water tank storing water and an antifreeze solution tank storing an antifreeze solution. The water tank and the antifreeze solution tank are provided with heat exchangers, respectively.  Pumps are further provided for feeding the water and the antifreeze solution in the respective tanks to a spray nozzle for spraying out a mixture of the water and the antifreeze solution. A gas turbine is provided for driving the foregoing pumps. Exhaust gas of the gas turbine is introduced into the heat exchangers through a control of valve switching so as to hold temperatures of the water and the antifreeze solution in the respective tanks to be constant. Further, bleed air of the gas turbine is fed to an air nozzle so as to be jetted out therefrom.
Patent CA-2192352-A1 (CA)
Title: Medicament distribution system and automatic dispenser for such system
Inventor: SCHAAP CORNELIS WILHELMUS HENR
IPC: G16H20/13
Filed: 1995-06-09
Abstract: The invention relates to a pharmacy system for prescribing and delivering medicaments to a patient. The system comprises at least one input unit with which a doctor is capable of entering inter alia a prescription of a medicament for a patient, together with the patient's identity into the system. The input unit then generates a prescription signal corresponding to the prescription entered. A pharmacy computer coupled to the input unit further processes the prescription signal received from the input unit and generates a control signal corresponding to the prescription. Under the supply of the control signal generated by the pharmacy computer, an automatic dispenser dispenses the described medicament to the patient.
Patent CA-2192658-A1 (CA)
Title: Body mountable carrier
Inventor: FLOWERS DANNY J
IPC: A45F5/02
Filed: 1995-06-16
Abstract: A body mountable carrier (10) for carrying a detachable device such as a portable phone, tool, or appliance. The carrier has a firm mounting panel (12) to which is attached an elastic strap (14). The panel and the strap are joined together with mating interlocking fastening materials (34) and can be mounted on an arm with one hand or on a leg. The panel provides a back plane (24) for attachment of the detachable device.
Patent CA-2195358-A1 (CA)
Title: High Thrust Drive System and Device Employing Same
Inventor: SCHNEIDER MARK C
IPC: B05C17/01
Filed: 1997-01-17
Abstract: A high thrust drive system usable in a variety of devices, e.g.,  fluid dispensing,  article clamping,  article lifting and article jacking, includes a driving rod member, an actuating member movable through a driving stroke and a return stroke, and a gripping plate having a passage therein through which the driving rod extends for gripping the driving rod and moving the rod in a thrust-applying direction during the driving stroke of the actuating member.  The actuating member imposes a high thrust on the driving member through the gripping plate during the driving stroke, and the gripping plate imposes a torque on the driving rod in a first rotational direction as the actuating member is moved through the driving stroke.  A recoil plate is oriented to grip the driving rod during the return stroke of the actuating member and impose a torque on the driving rod in the same first rotational direction as the gripping plate to precule movement of the driving rod in a direction opposite the thrust-applying direction, whereby applying a torque on the driving rod in the same rotational direction during the driving and return strokes of the actuating membrer imparts a smooth, linear motion to the driving rod as the driving rod is moved in the thrust-applying direction.
Patent CA-2198521-A1 (CA)
Title: Ozone storing method and ozone storage system
Inventor: TANIMURA YASUHIRO
IPC: C01B13/10
Filed: 1997-02-26
Abstract: An ozone storage system which allows energy required for producing and storing ozone to be reduced and which supplies ozone as stored to an ozone consumer stably in continuation.  The system includes an ozone generator (1) for generating an ozonized oxygen gas from an oxygen containing gas by using electric energy, an adsorption/desorption tower (4) including an adsorbing means for adsorbing ozone from the ozonized oxygen gas and desorbing means for desorbing ozone from the adsorbent, a circulation pipe (L1) for feeding back the oxygen containing gas to the ozone generator (1) after adsorption of ozone in the adsorption/desorption tower (4), an ozone discharging means (11) for discharging ozone desorbed from the adsorption/desorption means (4), an ozone concentration controlling means (14) for adjusting an amount of ozone extracted through the ozone discharging means (11) to thereby supply an ozone containing gas containing ozone substantially at a predetermined constant concentration to an ozone consumer (15), and a low-temperature processing unit (20) for separating oxygen from air to feed an oxygen gas to the ozone generator (1).
Patent CA-2198615-A1 (CA)
Title: Method of investigating the interaction of biomolecules using surface plasmon resonance
Inventor: HABERMANN BIANCA
IPC: G01N33/547
Filed: 1995-09-21
Abstract: The invention concerns a process, a biosensor unit which can be regenerated and suitable kits for investigating the interaction between biomolecules by means of surface plasmon resonance (SPR). One of the reagents, a (poly)peptide, is coupled to the surface of the biosensor unit by means of a metal chelate. Nitrilotriacetic acid derivatives to which proteins with an affinity peptide containg histadine groups can be bonded are preferably used as chelate formers.
Patent CA-2200141-A1 (CA)
Inventor: HAWKINS ROBERT
IPC: E04D13/04
Filed: 1997-03-17
Abstract: An improved roof drain is provided having a wide flange, a base, and a means to secure attachments such as strainers to the base. The attachment means is characterized by being simple and permanent. In one embodiment, the strainer contains a peripheral flange which is rolled-into the large horizontal flange of the base during fabrication. Other attachments such as gravel stops and the like may be attached in a similar fashion. The base is an integral piece typically made from spun aluminum. An alternative embodiment includes a two-part generally annular clamping ring, the lower portion of which includes integral threaded studs. The lower portion of the clamping ring is permanently attached to the base again by being rolled into the large flange on the base.
Patent CA-2201937-A1 (CA)
Inventor: OHSHIMA IEMITSU
IPC: C04B33/24
Filed: 1996-07-22
Abstract: Clay constitutes the three major elements of pottery and porcelain together with silica stone and feldspar. In recent years, however, a good clay having a high plasticity and a low impurity level is being exhausted. The invention provides a synthetic clay rich in water retention and the amount of watery coating formed and possessing plasticity and properties equal or superior to natural clay and a process for preparing the same. The synthetic clay comprises 30 to 65 % by weight of amorphous silica, 30 to 65 % by weight of alumina trihydrate, and 2 to 20 % by weight of at least one of sepiolite, palygorskite, and bentonite. It may be in the form of a slurry, a hydrous clay prepared by dehydrating a slurried synthetic clay, or a mass or dry powder prepared by dehydrating a slurried synthetic clay and drying the dehydrated clay.
Patent CA-2203060-A1 (CA)
Inventor: SCHIEL CHRISTIAN
IPC: D21F9/00
Filed: 1997-04-18
Abstract: Apparatus and method for laterally sealing a drainage gap of a twin-wire paper machine. This lateral sealing has contact only with the lower wire.  Between the upper wire and the lateral sealing, sealing is preferably effected by sealing water.  Since this lateral sealing is elastic, it can adapt itself to the movements of the lower wire.
Patent CA-2204873-A1 (CA)
Inventor: ERIKSSON HANS OSKAR
IPC: H04M19/00
Filed: 1995-11-08
Abstract: Etage d'attaque (1) destiné à commander les deux étages de sortie (2, 3) d'un amplificateur différentiel du circuit d'interface de lignes d'abonnés, ledit étage d'attaque (1) étant adapté pour générer quatre courants d'attaque en fonction, d'une part, de signaux transversaux et longitudinaux IT et IL, respectivement, rentrant dans l'étage d'attaque et, d'autre part, un circuit de référence IR, et pour transmettre ces courants d'attaque par paires aux deux entrées des étages de sortie (2, 3) d'un amplificateur différentiel, lesdits quatre courants d'attaque étant supérieurs à zéro.
Patent CA-2205419-A1 (CA)
Title: Replaceable consumable erosion detector
Inventor: WILLIAMS MICHAEL R
IPC: E21B47/10
Filed: 1997-05-14
Abstract: Detector means for the detection of abrasive material being carried by fluid passing through a wellhead includes an erosion block having a passage therein and a bore intercepting the passage. A probe is inserted into the bore of the erosion block, this probe having a contact zone exposed to the passage when the probe is inserted in the bore. The probe includes a first bore extension in the probe inboard of the surface of the contact zone. This first bore extension communicates with a first bore. A first pressure transducer means is provided for sensing pressure in the first bore and in the first bore extension connected thereto. The pressure transducer provides an electrical output indicative of a change in pressure in the first bore and is electrically coupled to a means for responding to the electrical output of the first pressure transducer.
Patent CA-2209256-A1 (CA)
Inventor: BELZILE LUC
IPC: B60T13/74
Filed: 1997-07-09
Abstract: The present invention relates to a system that  activate the electric brake on  a towed  vehicle without having  to install  a brake controlling device on the towing vehicle.
Patent CA-2210470-A1 (CA)
Inventor: NOLAN DANIEL A
IPC: C03B37/027
Filed: 1996-12-11
Abstract: A single mode optical fiber (36) suitable for use in an amplified fiber optic system (30) which includes an inner glass core doped with rare earth element and an outer transparent glass cladding. The fiber (36) exhibits a plurality of mode coupling sites formed at regular intervals along the length (L) of the fiber (36) which provides for a reduced DOP (Degree of Polarization). The sites are formed by a twist at regular intervals along the fiber length (L) by applying a torque to the fiber (36). The method of forming the fiber is also disclosed.
Patent CA-2212356-A1 (CA)
Title: Novel 4-substituted-3-peptidyl-azetidin-2-one derivatives useful as cysteine proteinase inhibitor
Inventor: GUO DEQI
IPC: A61K38/00
Filed: 1996-03-29
Abstract: Certain 4-substituted-3-peptidyl-azetidin-2-one compounds exhibit excellent cysteine proteinase inhibitory activity which can be used in the treatment of different diseases such as muscular dystrophy, bone resorption, myocardial infarction and cancer metastasis. These compounds are 4-substituted-3-peptidyl-azetidin-2-ones of formula (I) or pharmaceutically acceptable salts thereof, wherein R1 is hydrogen; C1-C6 alkyl which is unsubstituted or substituted; R2 is selected from the group consisting of hydrogen; C1-C6 alkyl which is unsubstituted or substituted; -XR6 wherein X is O, S, SO, or SO2; R6 is C1-C6 alkyl which is unsubstituted or substituted. Peptidyl group is a 1-2 amino acid residue wherein the free NH2 is unsubstituted or substituted with a protective group selected from the group consisting of aryloxy carbonyl, alkoxy carbonyl, substituted alkanoyl, arylalkanoyl, arylalkenoyl, heterocyclealkanoyl, heterocyclealkenoyl alkylsulphonyl, arylsulphonyl, arylalkanylsulphonyl, arylalkensulphonyl, heterocyclealkanylsulphonyl, heterocyclealkensulphonyl, and heteroarylsulphonyl.
Patent CA-2215845-A1 (CA)
Title: Wood chip screening apparatus with blades having nonlinear top edges
Inventor: MARRS GEVAN R
IPC: B07B1/12
Filed: 1996-03-25
Abstract: A wood chip screening system has an infeed end, outfeed end and elongated thin blades (40, 42) mounted for reciprocating motion extending therebetween. The blades (40, 42) are spaced apart to allow chips with an acceptable thickness dimension to pass therethrough. The improvement includes configuring the top edges of the blades (40, 42) in a nonlinear design.
Patent CA-2216366-A1 (CA)
Title: Arrangement and method at an integrated circuit
Inventor: HINTUKAINEN KARI
IPC: H03K5/13
Filed: 1996-03-27
Abstract: The present invention concerns an arrangement and process for mutually synchroni zing application-specific integrated circuits (ASIC) which are arranged to communicate with one another. The arrangement according to the invention enables an activating pulse edge to be determined in a common clock signal to an edge-triggered integrated circuit whic h communicates with at least one further integrated circuit. Each of the communicating integrated circuits receives the common clock signal. The circuits also receive frequency data in the form of a clock signal which is adapted to the respective circuit and which is used for de termining in the respective circuit the activating pulse edger in the common clock signal.
Patent CA-2219961-A1 (CA)
Title: Vasopermeability enhancing peptide of human interleukin-2 and immunoconjugates thereof
Inventor: KHAWLI LESLIE A
IPC: A61K47/48
Filed: 1998-01-09
Abstract: A novel permeability enhancing peptide (PEP) is a fragment of interleukin-2. When joined to a delivery vehicle that can target a tumor site, the PEP can increase the subsequent uptake of antineoplastic or tumor imaging agents. The PEP can be chemically joined to a monoclonal antibody to form an immunoconjugate.      Alternatively, an expression vector is genetically engineered to express a fusion protein. The fusion protein has an antigen-binding portion joined to the PEP. The PEP is most effective when it takes the form of a dimer, linked by a disulfide bridge. The PEP is substantially free of cytokine activity and produces minimal toxic side effects on normal tissues.
Patent CA-2220379-A1 (CA)
Title: Instrument de marquage
Inventor: NICOLL ROY
IPC: B43K7/10
Filed: 1996-06-27
Abstract: L'invention concerne un instrument de marquage, en particulier un stylo plume à réservoir, pourvu d'un diaphragme (8) qui est défléchi par retrait de la pointe de marquage pour ouvrir un orifice (7) et relier un canal d'alimentation (5) au réservoir (2) contenant le liquide de marquage. Le volume de la cavité (11) communiquant avec l'orifice (7) se réduit lorsque le diaphragme est défléchi pour ouvrir la valve et il s'agrandit lorsque le diaphragme se déplace pour fermer la valve. Le diaphragme dispose d'une jupe (10) intégrée qui s'étend en avant et qui se plaque hermétiquement contre l'élément d'alimentation (4) à l'extrémité antérieure de la jupe. Ces éléments empêchent le liquide de marquage de couler vers la pointe lorsque cela n'est pas nécessaire et les fuites de liquide de marquage entre le diaphragme et l'élément d'alimentation.
Patent CA-2221992-A1 (CA)
Title: N,n-di(arylmethyl)cyclic urea derivatives as anti-coagulants
Inventor: MORRISSEY MICHAEL M
IPC: C07D233/36
Filed: 1996-05-31
Abstract: N,N-di(aryl)cyclic urea derivatives, such as the compounds of formula (III) wherein R1 is -C(NH)NH2, -C(NH)N(H)OR11, -C(NH)N(H)C(O)R9, or C(NH)N(H)C(O)OR11; R2 and R3 are independently hydrogen, halo, lower alkyl, lower haloalkyl, aryl, -OR11, -C(O)OR11, -C(O)N(R11)R12, -N(R11)R12, N(H)C(O)R11, or -N(H)S(O)2R11; R4 is halo, lower haloalkyl, imidazolyl, C(NH)NH2, -C(NH)NHOR11, -C(NH)N(H)C(O)R9, -C(NH)N(H)C(O)OR11, -OR11, -C(O)R13, -(CH2)nC(O)OR11 (where n is 0 to 6), -C(O)N(R11)R12, or -N(R11)R12; R7 and R8 are independently hydrogen, lower alkyl, lower haloalkyl, 4-pyridinyl, C(O)OR11, -C(O)N(R11)R12, or aryl (optionally substituted by one or more substituents selected from the group consisting of halo, hydroxy, lower alkyl, lower haloalkyl, lower alkoxy and -N(R11)R12); R11 and R12 are independently hydrogen, lower alkyl, aryl or lower aralkyl; or R13 is pyrrolidinyl, 4morpholinyl, piperazinyl, N-methylpiperazinyl, or piperidinyl; or a pharmaceutically acceptable salt thereof, are disclosed herein as being inhibitors of factor Xa and thereby being useful as anti-coagulants.
Patent CA-2222233-A1 (CA)
Title: Rectal plug and method of introducing same into a slaughtered animal
Inventor: ANDERBERG STEVEN L
IPC: A22C21/00
Filed: 1996-05-20
Abstract: Fecal leakage and contamination from the vent opening of an animal carcass during slaughtering and processing is eliminated by injecting a highly viscous material comprising a mixture of food grade constituents through the vent opening so as to create a self-adhering plug in the lower colon and rectum of the animal. The plug material preferably comprises a blended mixture of water, gum, modified food starch and a preservative whose viscosity is in the range of from about 220,000 centipoise to 480,000 centipoise. Being formed from food grade constituents, the offal can safely be harvested and used in animal feed as a by-product of the meat processing operation.
Patent CA-2223076-A1 (CA)
Inventor: MARCHITELLI CINZIA
IPC: C07K14/415
Filed: 1997-12-18
Abstract: A description  follows  of  the  isolation  and characterization  of  a  gene which  encodes  a  low molecular weight glutenin strictly correlated with the good qualitative characteristics of durum wheat meal and bran, a recombinant vector comprising said gene, a microorganism transformed with this vector and transgenic plants comprising said gene.
Patent CA-2223825-A1 (CA)
Inventor: LE CONTEL CAROLE
IPC: G01N33/569
Filed: 1996-06-28
Abstract: PCT No. PCT/FR96/01006 Sec. 371 Date Feb. 19, 1997 Sec. 102(e) Date Feb. 19, 1997 PCT Filed Jun. 28, 1996 PCT Pub. No. WO97/02344 PCT Pub. Date Jan. 23, 1997An immunogenic composition for treating and/or preventing infectious diseases where the infectious agent has at least one intracellular phase in the host during its multiplication cycle, is disclosed. The immunogenic composition comprises at least one cryptic epitope of a cellular element that is carried along by an intracellular infectious agent as it leaves the cell, and revealed by said infectious agent. A composition for treating and/or preventing HIV infections, antibodies to a peptide of interest, and a diagnostic method, are also disclosed.
Patent CA-2226166-A1 (CA)
Title: Biocompatible and biodegradable nanoparticles designed for proteinaceous drugs absorption and delivery
Inventor: JEROME ROBERT
IPC: A61K9/51
Filed: 1996-07-02
Abstract: A polymer blend obtainable by a process comprising the steps of intimate mixing a biocompatible polymer able to form nanoparticles and a biocompatible interacting agent for making the polymeric blend susceptible for a drug to be administered which interacting agent is able to preserve the activity of the drug to be administered and which interacting agent is able to control the release of the drug to be administered.
Patent CA-2226511-A1 (CA)
Title: Process for the manufacture of a unit containing a solid active material which can be used for producing cold, unit obtained and refrigerating device comprising this unit
Inventor: BOYE PHILIPPE
IPC: B01J3/04
Filed: 1996-07-05
Abstract: A method for making a unit including a pressure-sealed container (2) with at least one connecting port (3), and an active solid (1) placed in said container (2). The container (2) is formed directly on a preformed body of the active solid (1) and made of a material having a thermal conductivity of more than 18 W/m. K. The resulting units are particularly useful for making portable air-conditioning devices for garments.