baber/WOPTO huggingface dataset:
Patent PT-1242603-E (PT)
Inventor: HOLLENBERG CORNELIS P
IPC: C12N9/16
Filed: 2000-11-23
Abstract: The invention relates to integration vectors for the targeted and stable integration of heterologous DNA into the genome of a host organism, especially a fungus, and to the use thereof. The invention also relates to a method for producing one or more recombinant proteins using the inventive vectors. The aim of the invention is to provide integration vectors which enable foreign DNA to be integrated into the genome of a host organism in a stable manner and with a high copy number and if necessary, to enable different genes to be expressed for a simultaneous coproduction of different proteins. Another aim of the invention is provide stable production strains and a method for producing heterologous proteins. To this end, an integration vector comprising the following is provided: a) at least one rDNA sequence from yeast; b) at least one non-deficient selection marker gene; and c) at least one expression cassette, said expression cassette comprising a promoter element that is functional in the host organism, an area of a heterologous or genuine gene that code for a desired protein and a terminator element that is functional in the host organism. The invention also comprises a host organism containing at least one inventive vector. A preferred organism is the methylotrophic yeast    Hansenula polymorpha    .
Patent PT-1103326-E (PT)
Inventor: HANSE ERIC
IPC: B22D41/22
Filed: 1996-10-25
Abstract: The present invention concerns a plate for a slide gate with indentation. The plate is characterized in that it is asymmetric relative to its axes (XX, YY) so as to cooperate with a complementary form (34) of the indentations in order to define an aligning device that permits it to be mounted only in one position in the upper indentation (14) and in only one position in the lower indentation (18). The combination of both the plate and the slide gate permit efficient and safe recycling of the plates after a step of cleaning, repairing or reconditioning of the plate surface. <IMAGE>
Patent PT-1166562-E (PT)
Title: Digital content delivery system and method
Inventor: SHEN-ORR CHAIM
IPC: H04N/
Filed: 2001-01-04
Abstract: A method for flexible and secure transmission of digital content to an end user device comprises the steps of: (a) providing a control center (240) for controlling access to the digital content by the end user device (310); (b) transmitting scrambled digital content to a first end user device (310) by a second end user device (310), such that said second end user device cannot play back said scrambled digital content; (c) connecting said second end user device (310) to said control center (240); and (d) transmitting a permission message to said second end user device (310) by said control center (240), such that said second end user device is able to unscramble said scrambled digital content to form unscrambled digital content.
Patent PT-1272312-E (PT)
Inventor: POUL LUNDUM
IPC: B24D13/06
Filed: 2001-04-10
Abstract: A sanding strip with a sanding means for a sanding wheel mounted on a rotatable axle is provided. The sanding strip includes brushes placed in spaced brunches in a profile rail, where the sanding means are fastened directly to the front of the brushes outside the profile rail, preferably by means of extended glue which penetrates into the spaces between the brush bunches, whereby there is achieved an effective anchoring of the sanding means, and a sanding strip which is flexible to accommodate outwards bending in the sideways directions.
Patent PT-1299648-E (PT)
Title: Body pulsating apparatus
Inventor: HANSEN CRAIG N
IPC: F04B45/04
Filed: 2001-07-12
Abstract: A vest for a human body has an air core coupled to a pulsator operableto subject the vest to pulses of air which applies and releases high frequency pressure forces to the body. The pulsator has two diaphrams connected to an electric de motor with rotary to reciprocating linear motion transmitting mechanisms operable to generate air pulses in an air pulsing chamber. The diaphragms also increase the pressure in a manifold chamber. A check valve connects the manifold chamber with a pulsing chamber to allow pressurized air to flow from the manifold chamber into the pulsing chamber. An air flow control valve in commmunication with the manifold chamber is used to adjust the pressure of the air in the manifold and pulsing chambers.
Patent PT-1246454-E (PT)
Title: A case for television camera
Inventor: GROTTO ALESSIO
IPC: H04N5/225
Filed: 2002-03-18
Abstract: A case for a television camera is constituted by a wrapper or a container, in the interior of which are located in addition to the television camera which is the relative object, a feeder, a heat dissipator ventilator for cooling, and other components, as well as the necessary electrical connections between the several components and the external connection. The case is characterized by the fact that it is constituted by two parts which are counterposed and approached one to the other. The upper part has essentially a convex configuration while the lower part has essentially a planar configuration. <IMAGE>
Patent PT-1432805-E (PT)
Inventor: FUERTES LAURA LOPEZ
IPC: C07K14/44
Filed: 2002-10-02
Abstract: DNA expression construct for the treatment of infections with leishmania, as well as a corresponding vaccine. This vaccine serves to immunise against leishmaniasis, where in particular the immunogenic p36 LACK antigen is used to elicit an immune response. As a gene shuttle, a linear double stranded, covalently closed expression cassette is employed. The gene expression construct can be attached to an oligopeptide to increase transfection efficacy. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading "Abstract of the Disclosure." The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.
Patent PT-1342763-E (PT)
Title: Acrylic pressure-sensitive adhesive composition and pressure-sensitive adhesive tape
Inventor: ISHIGURO SHIGEKI
IPC: C09J7/22
Filed: 2003-02-25
Abstract: The present invention relates to an acrylic pressure-sensitive adhesive composition containing an acrylic polymer and a tackifier obtained by acid modification of a tackifier resin inherently free of an acid component; a pressure-sensitive adhesive tape including a substrate made of a film comprising an olefin polymer or a thermoplastic resin containing a carbonyl oxygen atom in the molecular skeleton, and the acrylic pressure-sensitive adhesive composition on at least one surface of-the substrate, and the like. The invention provides an acrylic pressure-sensitive adhesive composition having high adhesive strength (particularly initial adhesive strength) to an adherend having lower polarity, such as an olefin polymer heretofore been considered poorly adhesive, wherein degradation of the adhesive strength after heating and preservation has been suppressed, as well as a pressure-sensitive adhesive tape comprising the composition. The pressure-sensitive adhesive tape of the present invention is also useful for binding.
Patent PT-1466638-E (PT)
Title: Prefilled syringe or carpule for medical purposes
Inventor: VETTER UDO J
IPC: A61M5/31
Filed: 2003-12-13
Abstract: The ampoule or capsule (1) has an undercut neck allowing a cap (2) containing a cannula (3) to snap into place. Both ends of the cannula are sharp and the inner end can pierce a membrane which seals the fluid into the ampoule until it is used. The cannula is held in a boss (13). A protective cap (8) covers the outer end of the cannula until it is used. It has a ring or skirt (9) which snaps onto the cannula cap. The interior lining of the protective cap (12) is made of rubber.
Patent PT-1422799-E (PT)
Title: Power distribution device for electrical devices
Inventor: ARAUJO FERNANDO
IPC: H02B1/20
Filed: 2003-11-19
Abstract: The electrical energy distribution bar (100) includes a longitudinal bar (110) with electric connectors (120) along its length. The bar includes an insulating envelope (111) within which there are two parallel rigid bars of electrically conducting material, each having connection terminals for associated equipment.  The electrical energy distribution bar (100) serves electrical equipment arranged in parallel rows situated at different levels on a board. This includes a longitudinal bar (110) provided with electric connectors (120) distributed along its length, the bar lying at right angles to the rows of equipment. The longitudinal bar includes an insulating envelope (111) within which there are two parallel rigid bars of electrically conducting material. Each has a connection terminal (122,122) to be plugged into a corresponding connection terminal in the equipment situated on one of the rows. Each electrical connector on one bar is juxtaposed with an electrical connector on the other bar forming a connection pair.
Patent PT-1587449-E (PT)
Title: Varying-diameter vascular implant and balloon
Inventor: BEN-MUVHAR SHMUEL
IPC: A61F2/958
Filed: 2003-11-25
Abstract: A method for deploying an expandable implant in a body passage of varying diameter includes selecting a balloon having a radial dimension that varies, when the balloon is inflated, in accordance with the varying diameter of the body passage. The balloon is inserted, in a deflated state, into the body passage, with the expandable implant fitted radially around the balloon. The balloon is inflated so as to cause the implant to open, responsively to the varying radial dimension of the balloon, into an expanded shape that approximately matches the varying diameter of the body passage, thus anchoring the implant in the body passage.
Patent PT-1708711-E (PT)
Title: Compositions useful especially for treatment or prevention of metabolic syndrome
Inventor: JALKANEN MARKKU
IPC: A23L33/15
Filed: 2005-01-19
Abstract: This invention concerns the use of an amine oxidase enzyme inhibitor for the manufacture of a pharmaceutical preparation useful in the treatment or prevention of metabolic syndrome and diseases or conditions resulting therefrom. The invention concerns also the use of vitamin B1 or a metabolite thereof for the manufacture of a pharmaceutical preparation useful as an amine oxidase enzyme inhibitor. Furthermore, the invention concerns a food product comprising an amine oxidase enzyme inhibitor in combination with a foodstuff, a food additive comprising an amine oxidase enzyme inhibitor in combination with a liquid, solid or semisolid carrier.
Patent PT-1723047-E (PT)
Title: Prepacked serving for espresso coffee machine, and dispensing unit suitable for use with the said serving
Inventor: BARDAZZI BRUNO
IPC: B65D85/804
Filed: 2005-03-07
Abstract: Prepacked serving of coffee powder, particularly for an espresso coffee making machine, comprising a cartridge (1) enclosing a given portion of coffee powder (40), the said cartridge (1) comprising an essentially cylindrical side wall (101) provided at its two ends with a first wall (201) designed to be acted upon by the pressurized hot-water supply means, and with a second wall (301) designed to be acted upon by the brewed coffee dispensing means, the said cartridge (1) being made of an essentially airtight material, and the said wall (301) being continuous and made of a thermoplastic material.
Patent PT-1747023-E (PT)
Title: Methods and compositions for reducing hcv viral genome amounts in a target cell
Inventor: SARNOW PETER
IPC: A61K48/00
Filed: 2005-05-03
Abstract: Methods and compositions for reducing viral genome amounts in a target cell are provided. In the subject methods, the activity of a miRNA is inhibited in a manner sufficient to reduce the amount of viral genome in the target cell, e.g., by introducing a miRNA inhibitory agent in the target cell. Also provided are pharmaceutical compositions, kits and systems for use in practicing the subject methods. The subject invention finds use in a variety of applications, including the treatment of subjects suffering from a viral mediated disease condition, e.g., an HCV mediated disease condition.
Patent PT-1877559-E (PT)
Title: Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
Inventor: PARR RYAN
IPC: A61P35/00
Filed: 2006-04-18
Abstract: Mitochondrial DNA (mtDNA) deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.
Patent PT-1885690-E (PT)
Title: Process for preparation of alkyl and alcoxyalkyl-alpha -cyanoacrylates by depolymerisation of poly(alkyl-alpha cyanoacrylates) or poly(alcoxyalkyl-alpha -cyanoacrylates) and its usage as technical and/or medical adhesive
Inventor: DENCHEV ZLATAN ZLATEV
IPC: C07C253/32
Filed: 2006-05-05
Abstract: This invention is related to the preparation of alkyl or alkoxyalkyl-alpha-cyanoacrylates in monomeric form by depolymerisation of the corresponding poly(alkyl-alpha-cyanoacrylates) or poly(alkoxyalkyl-alpha-cyanoacrylates) (PCA). The PCA's are obtained preferably by base-catalyzed condensation of a cyanoacetate with formaldehyde (or a polymer of the latter). According to the invention, the poly(alkyl-alpha-cyanoacrylate) or poly(alkoxyalkyl-alpha-cyanoacrylate), the condensation product, is mixed with a depolymerisation system comprising phosphorus pentoxide P2O5, hydroquinone, ortho-phosphoric acid and para-toluenesulfonic acid. This process is realized in a batch reactor fitted with a condenser, heated at a temperature in the range of 100-300° C., under a vacuum of 0.5-50 Torr (7.10-5-7.10-3 MPa) and gives rise to monomeric alkyl-alpha-cyanoacrylates or monomeric alkoxyalkyl-alpha-cyanoacrylates, being stable in both gaseous and liquid phase. After an additional purification by vacuum distillation, these cyanoacrylates can be used as fast setting technical or medical adhesives.
Patent PT-1951692-E (PT)
Title: Oxazole and thiazole ppar modulator
Inventor: EPPLE ROBERT
IPC: A61K31/422
Filed: 2006-11-07
Abstract: The invention provides compounds (I) pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPARδ.
Patent PT-1832390-E (PT)
Title: Nosepiece and shear block assembly for a fastening tool and said fastening tool
Inventor: LAUBACH MARCO
IPC: B25C7/00
Filed: 2003-05-23
Abstract: A tool has an improved nosepiece and shear block assembly (12) that drives a fastener supplied from a plurality of fasteners. The assembly includes a nosepiece (22) that is configured for attachment to the tool and defines a portion of a barrel and a shear block (40) configured to be secured to the nosepiece (22) to compete the barrel. The shear block has a boss (52). The nosepiece has a workpiece contact element (56) having one cap (54) to engage the boss when the workpiece contact element (56) engages a workpiece (16).
Patent PT-2069531-E (PT)
Title: Qtls for mastitis resistance in cattle
Inventor: BENDIXEN CHRISTIAN
IPC: C12Q1/68
Filed: 2007-02-05
Abstract: The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis.
Patent PT-1999401-E (PT)
Title: Bypass device for fluid circuit and circuit comprising same
Inventor: CHEVALIER GILBERT
IPC: F16K43/00
Filed: 2007-03-14
Abstract: The invention concerns a bypass device for a fluid circuit, in particular a gas circuit (4, 8) for circulating fluid comprising two separate sections (4, 8) for circulating fluid provided each with an upstream end and a downstream end, the upstream end of each fluid circulating section (4, 8) being capable of being in fluid communication with a fluid input port (E) of a circuit, the downstream end of each section (4, 8) being capable of being in fluid communication with a fluid output port (S) of a circuit. The invention is characterized in that each circulating section (4, 8) is mounted mobile relative to a fixed base (1, 6) between a first position in which the upstream and downstream ends of said section (4, 8) are in fluid communication with respectively the fluid input port (E) and output port (S), and a second retracted position in which the upstream and downstream ends (4, 8) of said circulating section (4, 8) are not in fluid communication respectively with the fluid input port (E) and output port (S), the two circulating sections (4, 8) being connected by a movement coupling element relative to the base (1, 6) between a first working position in which the upstream and downstream ends of a first section (8) are in fluid communication with respectively the fluid input port (E) and output port (S), and a second bypass position in which the upstream and downstream ends of the second section (4) are in fluid communication with respectively the fluid input port (E) and output port (S), the two sections (4, 8) are arranged relatively to the base (1, 6) such that, between the working position and the bypass position, the two sections (4, 8) pass through at least one intermediate position in which the upstream ends of the two sections (4, 8) are simultaneously in fluid communication with the fluid output port (S), to provide a bypass for the fluid of one section towards the other without interrupting the fluid flow between the input port (E) and the output port (S).
Patent PT-2001891-E (PT)
Title: Buprenorphine derivatives and uses thereof
Inventor: BOURNE CHAPLEO CHRISTOPHER
IPC: A61K31/485
Filed: 2007-03-27
Abstract: Ester derivatives of the phenolic hydroxyl group of buprenorphine can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential.
Patent PT-2048836-E (PT)
Title: Dynamic media authorization in mobile networks
Inventor: RASANEN JUHA A
IPC: H04W28/24
Filed: 2004-02-10
Abstract: The disclosure relates to an apparatus and method for determining if a media stream requiring a highest traffic class within a plurality of media streams is removed from a session, when the session established is modified between two mobile terminals or between a mobile terminal and a server, via a communication link. The existing traffic class is maintained for the remaining media streams for the session, if the media stream requiring the highest traffic class is removed from the session.
Patent PT-629238-E (PT)
Inventor: KRUTZSCH HENRY C
IPC: C07K16/00
Filed: 1993-01-15
Abstract: The present invention relates, in general, to autotaxin. In particular, the present invention relates to a DNA segment encoding autotaxin; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing autotaxin; and antibodies to autotaxin.
Patent PT-783323-E (PT)
Inventor: MOAN JOHAN
IPC: A61K41/00
Filed: 1995-09-04
Abstract: The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.
Patent PT-871645-E (PT)
Title: Modulators of the function of fas/apo1 receptors
Inventor: WALLACH DAVID
IPC: C07K14/715
Filed: 1995-12-14
Abstract: Proteins capable of modulating the function of FAS/APO1 are provided. The proteins may be prepared by culturing a host cell transformed with a vector containing the DNA encoding such a protein under suitable conditions and isolating the protein.
Patent PT-863912-E (PT)
Inventor: TANG JIN-YAN
IPC: C07H21/00
Filed: 1996-11-27
Abstract: The invention provides passivated organic polymer supports, processes for their preparation and processes for their use in oligonucleotide synthesis that allow for highly efficient solid phase synthesis of oligonucleotides.
Patent PT-796718-E (PT)
Inventor: ANDERSSON MIKAEL
IPC: B29C65/74
Filed: 1997-03-18
Abstract: The invention relates to a method and an apparatus for induction sealing of a packaging material (2) which includes a layer of aluminium foil. The apparatus includes an inductor (1) with two parallel slightly spaced apart conductors (3) which are disposed in an electrically insulated carrier portion (4). The conductors are connected to one another and to a high frequency current source by means of two transverse conductors (6, 7). The transverse conductors (6, 7) are placed in the upper surface (8) of the inductor (1) and coincide with the outer defining lines (13) of the flat-laid material tube (2). Hereby, the current is led in a controlled fashion from the one conductor (3) to the other and a power output requirement is obtained for sealing the central zone of the packaging material (2) which is of the same magnitude as for the sealing of the edge zones of the packaging material (2). The inductor (1) of the above-described type is particularly adapted for sealing packaging material (2) which encloses products that are viscous, for example, tomato paste or fibrous products. <IMAGE>
Patent PT-816376-E (PT)
Inventor: KLIMKOWSKI VALENTINE JOSEPH
IPC: C07D217/26
Filed: 1997-06-25
Abstract: This invention relates to a compound of the Formula I X-C(O)-Y-G-R (wherein X, Y, G and R have the values defined in the description), or a pharmaceutically acceptable salt thereof, processes and intermediates for the preparation of such a compound or salt, pharmaceutical compositions comprising such a compound or salt and methods of their use as thrombin inhibitors, coagulation inhibitors and agents for the treatment of thromboembolic disorders.
Patent PT-951287-E (PT)
Inventor: BUSER THOMAS
IPC: A61K47/14
Filed: 1997-08-12
Abstract: A topical spreadable composition comprising 5-aminosalicylic acid (5-ASA) as active and monoolein is provided for treatment ulcers, inflammation and lesions of the oral cavity. The composition is spread over and adheres to the lesion, and is preferably prepared in a water free state. Examples of indications that can be treated are oral Crohn's Disease, apthous ulcers, orofacial granulomatosis, oral ulcers associated with Behet's disease and oral lichen planus.