baber/WOPTO huggingface dataset:
Patent ES-2066744-T1 (ES)
Inventor: DONATO RUSSELL DI
IPC: B41F17/22
Filed: 1991-08-09
Abstract: A continuous motion decorator (Fig. 1) of the type in which cans 16 are supported on freely rotatable mandrels 20 during decorating is provided with a plurality of equally spaced mandrel actuator subassemblies 40 mounted along the periphery of a rotating carrier 18. Each subassembly 40 is mounted for radial movement toward and away from the carrier's rotational axis 19 with the radial position of the subassembly 40 being controlled by a stationary closed loop cam track 52 on which a follower roller 48, 49 of the subassembly 40 is disposed. The subassembly 40 also includes a rotary operator 42-44 having a rotor 43 that supports the mandrel 20 and is on a pivot axis 47 that is parallel to the axis 19 of the carrier as well as being parallel to and laterally offset from the rotational axis 46 of the mandrel 20. Sensors 33 detect unloaded and misloaded mandrels 20, and upon doing so cause the rotary operator 42-44 that is unloaded or misloaded to be actuated to withdraw the rotor 43 from its normal decorating path so that it will not engage the printing blanket 21 of a decorating unit 22. <IMAGE>
Patent ES-2041225-T1 (ES)
Title: Tambor cribador.
IPC: B07B1/24
Filed: 1992-11-19
Abstract: EN UN TAMBOR DE CRIBADO, ESPECIALMENTE PARA BASURAS DOMESTICAS O BASURAS INDUSTRIALES SIMILARES A LAS DOMESTICAS, RESIDUOS FERMENTADOS, CHATARRA DESMENUZADA DE TODO TIPO, ETC., CON ELEMENTOS INCORPORADOS, SE OBTIENE UN SERVICIO PERFECCIONADO, SI SON FIJADOS DEDOS (8,14) EN FORMA DE ALMAS DIRIGIDOS HACIA EL EJE CENTRAL (5) DEL TAMBOR, SOBRE LA SUPERFICIE INTERIOR DEL TAMIZ PERFORADO (6).
Patent CY-1107569-T1 (CY)
Title: Μεθοδος αυτοματης διαχειρισης πληροφοριων εξαρτημενων απο το τepματικο
Inventor: BERGQVIST PER
IPC: H04W4/02
Filed: 2007-02-27
Abstract: Η παρούσα εφεύρεση αφορά σε μια μέθοδο αυτόματης διαχείρισης πληροφοριών εξαρτημένων από το τερματικό σε ασύρματο σύστημα επικοινωνίας. Η μέθοδος περιλαμβάνει τα βήματα: - εντοπισμού της μοναδικής ταυτότητας του τερματικού που ο συνδρομητής χρησιμοποιεί την τρέχουσα περίοδο· - προσαρμογής των πληροφοριών στον τύπο του τερματικού που εντοπίστηκε και - παρουσίασης των προσαρμοσμένων πληροφοριών στο εν λόγω τερματικό.
Patent CY-1106916-T1 (CY)
Inventor: ZARIF LEILA
IPC: A61P31/04
Filed: 2007-10-08
Abstract: A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
Patent CY-1110424-T1 (CY)
Inventor: VALE WYLIE W
IPC: C12N15/64
Filed: 2008-12-17
Abstract: A human urocortin-related peptide with significant sequence homology to the CRF neuropeptide family was identified. A mouse cDNA was isolated from whole brain poly (A+) RNA that encodes a predicted 38 amino acid peptide protein designated herein as urocortin II. Both human URP and mouse Ucn II are structurally related to the other known mammalian family members, CRF and urocortin (Ucn). These peptides are involved in the regulation of the hypothalamic-pituitary-adrenal axis under basal and stress conditions, suggesting a similar role for URP and Ucn IL Synthesized Ucn-II and URP peptide binds with higher affinity to CRF-R2 than to CRF-R1 Ucn II and human URP appear to be involved in the regulation of body temperature and appetite and may play a role in other stress related phenomenon. These findings identify Ucn II and human URP as a new members of the CRF family of neuropeptides, which are expressed centrally and bind to CRF-R2.
Patent CY-1108973-T1 (CY)
Title: Ξηρα κοκκοποιημενη συνθεση η οποια περιλαμβανει εμτρισιταβινη και τενοφοβιρη df
Inventor: DAHL TERRENCE C
IPC: A61K9/16
Filed: 2009-04-03
Abstract: Αυτή η εφεύρεση απευθύνεται σε μια σύνθεση η οποία περιλαμβάνει την ξηρά κοκκοποιημένη τενοφοβίρη DF και την εμτρισιταβίνη, και μια μέθοδο για την κατασκευή της. Η ξηρά κοκκοποίηση βρέθηκε απροσδόκητα να είναι σημαντική στην παρασκευή μιας σύνθεσης που περιέχει τενοφοβίρη DF κατάλληλης για συμπερίληψη σε μια μορφή δοσολογίας συνδυασμού που περιέχει εμτρισιταβίνη, εφαβιρένζ και τενοφοβίρη DF.
Patent CY-1115882-T1 (CY)
Title: Εγκατασταση αιολικης ενεργειας και μεθοδος για τη λειτουργια μιας εγκαταστασης αιολικης ενεργειας
Inventor: WOBBEN ALOYS
IPC: F03D7/02
Filed: 2014-12-29
Abstract: Η παρούσα εφεύρεση αναφέρεται σε μία μέθοδο για τη λειτουργία μίας εγκατάστασης αιολικής ενέργειας, με μία κινούμενη από ένα στροφείο γεννήτρια για την απόδοση ηλεκτρικής ισχύος σε έναν καταναλωτή ηλεκτρικής ενέργειας, κυρίως σε ένα ηλεκτρικό δίκτυο. Για τις ευρύτατα δυνατές αντιδράσεις στις διακυμάνσεις του δικτύου εξελίσσεται περαιτέρω η μέθοδος του αρχικώς αναφερθέντος είδους κατά τέτοιο τρόπο, ώστε η αποδιδόμενη από τη γεννήτρια στον καταναλωτή ισχύς να ρυθμίζεται σε συνάρτηση με το αποδιδόμενο στον καταναλωτή ρεύμα.
Patent CY-1116867-T1 (CY)
Title: Μεμβρανες με ενισχυμενα ακρα και ακμες
Inventor: JÄGER NORBERT
IPC: B32B37/22
Filed: 2015-10-15
Abstract: Η παρούσα εφεύρεση αναφέρεται σε μεμβράνες (Α) με ενισχυμένα άκρα (Β, Β') και ακμές, οι οποίες παρουσιάζουν χαμηλότερο κίνδυνο σχίσης των ακμών κατά την επεξεργασία, σε μία μέθοδο για την παραγωγή τέτοιων μεμβρανών, σε μία διάταξη για την παραγωγή τέτοιων μεμβρανών και στη χρήση τέτοιων μεμβρανών.
Patent CY-1117696-T1 (CY)
Title: ΝΕΑ ΠΑΡΑΓΩΓΑ ΚΥΚΛΟΕΞΥΛΑΜΙΝΗΣ ΜΕ ΔΡΑΣΕΙΣ β2 ΑΔΡΕΝΕΡΓΙΚΟΥ ΑΓΩΝΙΣΤΗ ΚΑΙ Μ3 ΜΟΥΣΚΑΡΙΝΙΚΟΥ ΑΝΤΑΓΩΝΙΣΤΗ
Inventor: AIGUADE BOSCH JOSE
IPC: A61P11/00
Filed: 2016-06-28
Abstract: Η παρούσα εφεύρεση αναφέρεται σε καινοτόμες ενώσεις που έχουν διπλή δράση β2 αδρενεργικού αγωνιστή και Μ3 μουσκαρινικού ανταγωνιστή, σε φαρμακευτικές συνθέσεις που τις περιέχουν, στη διαδικασία παρασκευής τους και στη χρήση τους σε θεραπείες του αναπνευστικού.
Patent CY-1119695-T1 (CY)
Title: Κρυσταλλικη μορφη της (s)-(2-(6-xλωpo-7- μεθυλ-1η-βενζο [d]ιμιδαζολ-2- υλ)-2- μεθυλπυρρολιδιν-1- υλ)(5-μεθοξυ-2-(2η-1,2,3- τριαζολ-2- υλ) φαινυλ) μεθανονης και η χρηση της ως ανταγωνιστης υποδοχεα ορεξινης
Inventor: BOSS CHRISTOPH
IPC: C07D403/14
Filed: 2017-12-12
Abstract: Η εφεύρεση αναφέρεται στην κρυσταλλική μορφή της (S)-(2-(6-χλωρο-7- μεθυλ-1Η- βενζο[d] ιμιδαζολ-2- υλ)-2-μεθυλπυρρολιδιν-1- υλ)(5- μεθοξυ-2-(2Η-1,2,3- τριαζολ-2- υλ) φαινυλ) μεθανόνης, σε διαδικασίες παρασκευής αυτής, σε φαρμακευτικές συνθέσεις που περιέχουν αυτές τις κρυσταλλικές μορφές, στις φαρμακευτικές συνθέσεις που παρασκευάζονται από αυτές τις κρυσταλλικές μορφές και στη χρήση τους ως φάρμακα, ειδικότερα ως ανταγωνιστές του υποδοχέα ορεξίνης.
Patent CY-1119719-T1 (CY)
Title: Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων
Inventor: HASILO CRAIG
IPC: C12N5/071
Filed: 2017-12-13
Abstract: Στο παρόν περιγράφονται λεπτομερώς οι συσκευές και οι μέθοδοι για τη μεταμόσχευση κυττάρων σε ένα σώμα ξενιστή. Το κύτταρο περιλαμβάνει ένα πορώδες ικρίωμα που επιτρέπει την ανάπτυξη των αγγειακών και συνδετικών ιστών, ένα βύσμα ή σύστημα βύσματος που είναι διαμορφωμένο, έτσι ώστε να τοποθετείται εντός του πορώδους ικριώματος και μία σφράγιση που είναι διαμορφωμένη, έτσι ώστε να περικλείει ένα εγγύτερο άνοιγμα στο πορώδες ικρίωμα. Η συσκευή μπορεί να περιλαμβάνει περαιτέρω μια συσκευή διανομής κυττάρων για την παροχή κυττάρων στο πορώδες ικρίωμα. Η μέθοδος της μεταμόσχευσης κυττάρων περιλαμβάνει μια διαδικασία δύο βημάτων. Η συσκευή επωάζεται στο σώμα του ξενιστή για να σχηματίσει μια μήτρα αγγειοποιημένου κολλαγόνου γύρω από ένα βύσμα που είναι τοποθετημένο μέσα στο πορώδες ικρίωμα. Στη συνέχεια, το βύσμα αφαιρείται από το πορώδες ικρίωμα και τα κύτταρα παρέχονται στον αγγειοποιημένο χώρο που δημιουργείται μέσα στο πορώδες ικρίωμα.
Patent CY-1123122-T1 (CY)
Title: Σκευασμα ντοξυλαμινης και πυριδοξινης ή/και μεταβολιτων ή αλατων αυτων
Inventor: VRANDERICK MANON
IPC: A61K9/00
Filed: 2020-07-17
Abstract: Περιγράφεται διπλής απελευθέρωσης από του στόματος σύστημα δοσολογίας/μορφή δοσολογίας περιλαμβάνουσα άμεσης απελευθέρωσης συστατικό/σύνθεση και καθυστερημένης απελευθέρωσης συστατικό/σύνθεση. Εκάστη από το άμεσης απελευθέρωσης συστατικό/σύνθεση και καθυστερημένης απελευθέρωσης συστατικό/σύνθεση περιλαμβάνει ένα ή περισσότερα από ντοξυλαμίνη, ανάλογο αυτής, παράγωγο αυτής, προφάρμακο αυτής, μεταβολίτη αυτής ή/και άλας αυτής, και ένα ή περισσότερα πυριδοξίνη, άλας αυτής, μεταβολίτη αυτής ή/και άλας του μεταβολίτη. Το διπλής απελευθέρωσης από του στόματος σύστημα δοσολογίας/μορφή δοσολογίας δεικνύει βελτιωμένο φαρμακοκινητικό προφίλ σε σχέση προς το τρέχον Diclectin® σκεύασμα και είναι χρήσιμο για παράδειγμα για την ανακούφιση των συμπτωμάτων ναυτίας και εμέτου, για παράδειγμα στην περίπτωση ναυτίας και εμέτου στην εγκυμοσύνη (NVP).
Patent GR-930300103-T1 (GR)
Title: Peat-derived bioactive products and pharmaceutical and cosmetic compositions containing them
Inventor: TOLPA STANISLAW
IPC: A61K8/00
Filed: 1993-10-29
Abstract: The peat-derived bioactive product contains not more than 70%, preferably not more than 60% by weight of inorganic salts, especially of sodium chloride, based on dry solids. It is obtainable by a process wherein a highly concentrated aqueous solution of inorganic salts, especially of sodium chloride containing peat-derived bioactive ingredients is diluted with demineralized water and subjected to reverse osmosis in order to desalinate the solution, inorganic salts being removed, and wherein the resulting solution is concentrated and clarified, and, optionally, in at least one further step, sterilized and/or spray-dried. A pharmaceutical formulation containing a peat-derived bioactive product, in the form of a gel, is prepared by combining a sterile alcoholic herb extract with sterile glycerol, a sterile aqueous solution of previously powdered peat-derived bioactive product and a sterile menthol solution; the resulting mixture is gradually combined with colloidal silica to convert the liquid composition into gel form, the weight ratio of liquid mixture to silica preferably being from 90:10 to 94:6. A cosmetic preparation such as a gel, ointment, balm, shampoo, bath salt lotion etc. contains as active ingredient the instant peat-derived bioactive product in a quantity of 0.01-10% by weight, preferably 0.05-1% by weight, more preferably 0.05-0.1% by weight.
Patent HR-P20130378-T1 (HR)
Title: Method of scavenging hydrogen sulfide from hydrocarbon stream
Inventor: SUBRAMANIYAM MAHESH
IPC: B01D53/14
Filed: 2013-05-02
Abstract: The invention is related to hydrogen sulfide scavenging additive, capable of scavenging hydrogen sulfide in hydrocarbons by forming water soluble scavenged products which are capable of getting separated from hydrocarbon even at acidic pH without causing fouling and decomposition problems, consisting of aldehyde or aldehyde and polyethylene glycol [PEG], and wherein said aldehyde is glyoxylic acid. The invention is also related to a method of scavenging hydrogen sulfide employing present scavenging additive.
Patent SI-1364713-T1 (SI)
Title: Blade mill for grinding plastic material and operating method therefor
Inventor: POLTINGER BRUNO
IPC: B29B17/04
Filed: 2003-05-16
Abstract: A stator roll(7) and rotor roll(3) form a granulating chamber(10) between them into stator knives(8) and rotor knives project. A cooling system(23) for cooling plastic material to be granulated supplies a coolant into the granulating chamber during the granulating cycle.  The coolant is a gas, preferably air, whose temperature is below the plastic solidification temperature of the material. Location of the cooling system is at designated points only, particularly just prior to the stator knives(8) and preferably on a holder for a stator knife. Coolant enters the granulating chamber(10) via small nozzles linked to a relatively large connecting bore and a transverse bore(23). Nozzle bores are radial to the cylindrical granulating chamber and coolant flowing through them lifts the plastic from the inner walls of the stator. Coolant is introduced intermittently, typically two or three times for each cycle with a single burst time of 5-8secs. An Independent claim is included for a method of operating the granulator in which, when a set threshold value of the rotor drive current exceeds a set value, the rotational speed of the rotor is reduced and coolant is introduced via the claimed cooling system into the granulating chamber.
Patent SI-1654286-T1 (SI)
Title: Humanized anti-cd4 antibody with immunosuppressive properties
Inventor: WIJDENES JOHN
IPC: C07K16/00
Filed: 2004-03-19
Abstract: Provided is a humanized anti-CD4 antibody which is capable of activating CD4 +  CD25 +  regulatory T cells, wherein the humanized anti-CD4 antibody comprises a sequence comprising the complementarity-determining regions (CDRs) of the mouse monoclonal anti-CD4 antibody B-F5, optionally with variations in the sequence that do not substantially affect the antibody specificity and/or affinity thereof.
Patent SI-1447604-T1 (SI)
Title: Method for the burying of tubular elements and mortar composition for carrying out this method
Inventor: LAFFITE HELENE
IPC: F16L1/036
Filed: 2004-02-12
Abstract: The procedure, especially for laying plastic gas pipes (2), consists of excavating a trench (1) and holding the pipe down with metal arches (7) while the trench is back-filled with a mortar (6), the arches leaving sufficient room for the pipe to rise and create a gap underneath that if filled with the liquid mortar. The procedure, especially for laying plastic gas pipes (2), consists of excavating a trench (1) and holding the pipe down with metal arches (7) while the trench is back-filled with a mortar (6), the arches leaving sufficient room for the pipe to rise and create a gap underneath that if filled with the liquid mortar. The mortar is designed to be self-compacting, chemically inert relative to the plastic pipes, resistant to frost when set, and able to withstand a pressure of at least 2 MPa; it can contain natural and/or synthetic fibres and is mixed with a water/ cement ration of between 0.8 and 2 : 1.
Patent SI-1753560-T1 (SI)
Title: Reclamation of ester-cured phenolic resin bonded foundry sands
Inventor: BUSBY ANDREW DAVID
IPC: B22C1/00
Filed: 2005-04-19
Abstract: A method of preparing a particulate refractory composition for use in the manufacture of foundry molds and cores from spent foundry molds or cores formed of refractory material and an ester-cured phenolic resin binder, the method comprising the steps of breaking up the spent foundry molds or cores, mixing the resulting broken material with a particulate pozzolan additive and subjecting the mixture to a heat treatment at a temperature in the range 450 to 900°.
Patent SI-2144721-T1 (SI)
Title: Method for the production of a wire strip comprising a plurality of wires arranged parallel to each other and wire strip produced according to said method
Inventor: STAHL KARL-HERMANN
IPC: B21D53/00
Filed: 2008-02-08
Abstract: The method serves for the production of a wire strip (1) comprising a plurality of wires (2) arranged parallel to each other. For this purpose a metal strip is first pre-notched either on one side or both sides for the formation of the wires (2), whereby wires (2) are generated which are still connected to webs (3). To transform the webs (3) subsequently into thin, easy to separate and, when separated, smooth and burr-free separation webs forming separation areas, the wire strip (1) is subjected to a milling process during which each web (3) is subjected to a multiple bending strain along the longitudinal axis thereof in such a way that incipient cracks form, due to fatigue fracture, in the area of the webs (3), and thereby the separation web is created.
Patent SI-2212297-T1 (SI)
Title: Inhibitors of protein kinases
Inventor: ALLGEIER HANS
IPC: A61K31/505
Filed: 2008-10-13
Abstract: Compounds of general Formula I: wherein R1, R2, R3, x, A and Ra are as defined herein are inhibitors of cyclin-dependent kinases and are useful for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.
Patent SI-2893045-T1 (SI)
Title: A method for selection of agents influencing intestinal motility disorders and pain
Inventor: CONNOLLY EAMONN
IPC: C12Q1/00
Filed: 2013-09-03
Abstract: A method is provided for evaluating agents for the treatment of different intestinal motility disorders, using distinct methodological parts related to musculature and nerves of the GI tract which communicate with the brain. In particular, the present invention provides a method for the selection of an agent effective for the treatment of an intestinal motility disorder, wherein said method comprises:
a) a step of spatiotemporal (ST) mapping carried out on a gastrointestinal segment to analyse the effect of said agent on gastrointestinal motility; and
b) a step of ex vivo nerve bundle recording carried out on a gastrointestinal segment to analyse the effect of said agent on mesenteric afferent nerve firing. 
     Bacterial strains selected by the methods of the invention and the use of said bacterial strains in the treatment of intestinal motility disorders are also provided.
Patent TR-200100042-T1 (TR)
Inventor: YASUMURA MASAYUKI
IPC: H02M3/335
Filed: 2000-05-10
Abstract: A switching power supply circuit of the resonance type which can handle high load power and has high power conversion efficiency, small size and light weight is provided. The switching power supply circuit may be formed as a composite resonance converter wherein a voltage resonance converter is provided on a primary side and a parallel resonance circuit is provided on a secondary side. The switching power supply circuit may include an insulating converter transformer having a pair of E-shaped cores each with outer and center legs in which a gap is formed between the middle legs thereof so that a loose coupling condition having a coupling coefficient higher than a predetermined level may be obtained. A half-wave rectifier circuit of an additive mode may be provided on the secondary side. A switching frequency of a switching element for switching a dc input voltage to the insulating converter transformer on and off may be varied to effect constant voltage control.
Patent TR-200703678-T1 (TR)
Title: Bir duvar kaplamasının kusurlarını saptamak için sistem ve böyle bir sistemi imal etmek için usul.
Inventor: VARGA L SZL
IPC: G01M3/04
Filed: 2005-11-29
Abstract: Buluş genellikle sıvı olan malzemelerin depolandığı bir alanı çevrelemeye yönelik, iç tarafında bir kaplama olan bir duvarın, özellikle bir konteyner duvarının kusurlarını ve/veya kaplamadaki kusurları saptamak için bir sisteme ilişkindir. Hayatın birçok alanında kimyasal maddeler, çözücüler, gaz yağı ve petrol fraksiyonları ve bunun gibi her tipten farklı malzemelerin, bu malzemelerin çevreye gitmesi veya çevreden başka malzemelerin depolanan malzemelerle karışması olasılığını dışlayacak bir şekilde depolanması gerekir. Çoğu durumda bu malzemeler farklı malzemelerden, çoğunlukla metalden yapılan konteynerlerde saklanır, bu konteynerlerin duvarlarında aşınma veya başka hasarların bir sonucu olarak delikler oluşabilir ve oluşan bu deliklerden dışarıdan konteynerin içine veya konteynerin içinden çevreye malzemeler akabilir ve böylece depolanan malzeme kullanım için uygun olmayan bir hale gelebilir veya ciddi çevre kirlenmesi söz konusu olabilir. Hasarı önlemek amacıyla, konteyner duvarlarında oluşan delikleri en kısa zamanda saptamak için farklı izleme sistemleri kullanılmaktadır.
Patent TR-200806733-T1 (TR)
Title: Mayalandırılmış fonksiyonel kabarcıklı içecek
Inventor: KWON TAE-GOOK
IPC: A23L19/10
Filed: 2007-03-06
Abstract: Açıklanan, kabarcıklandmlmış köpüklü bir içecektir. Kabarcıklandırılmış köpüklü içecek, çeşitli fonksiyonel gıdalara, özellikle, insanları içererek canlılarda biyolojik savunma ve fiziksel ritim kontrolü ve önleyici ilaçlar ışığında biyo-düzenleyici fonksiyonların harekete geçirilmesini kontrol eden fonksiyonlara sahip çeşitli mayalandırma teknikleri kullanılarak sağlanan mayalandırılmış gıdalara kabarcıklandırma mühendislik teknolojisi uygulayarak elde edilmektedir. Kabarcıklı  içecek,  köpüğün formasyon tepkimelerini yaratıcı  ve  kolay bir şekilde tasarlamak ve idare etmek için, kabarcıklandırma mühendislik teknolojisine dayanarak,  biyolojik   olarak   kullanılabilir   gıda   maddelerine   soğuk   kabarcıklandırma   işlemi uygulayarak üretilir. Kabarcıklı içecek içmeye uygundur; ve köpüklü yapının ortam basıncı ve sıcaklığında kolaylıkla elde edilebilmesi, köpüğün içsel özelliği olan madde akışının  istendik bir şekilde idare edilebilmesi,  ve önemli derecede ek harcama içermedenmodern endüstrinin özelliği olan  birim  işlemlerin  sıralı  otomatik  işlem sırasında çeşitlendirilebilmesiyle karakterize edilmiştir.
Patent DE-3685973-T2 (DE)
Inventor: NICHOLS LARRY
IPC: A61K47/38
Filed: 1986-03-13
Granted: 1992-12-24
Abstract: Gelled cellulose triacetate products are made by mixing with a solution of the cellulose triacetate an amount of miscible liquid nonsolvent agent insufficient to cause gelling, then cooling the mixture or evaporating the solvent to cause gelling. The products may be used as membranes for the transdermal delivery of medication.
Patent DE-3686201-T2 (DE)
Inventor: TAKAGI ATSUSHI
IPC: A61K31/435
Filed: 1986-05-23
Granted: 1993-01-07
Abstract: Benzo[ij]quinolizine-2-carboxylic acid derivatives of the general formula [I] and the salts, and their hydrates are provided:wherein A is a methylene group and B is a carbonyl group when A and B are linked by a single bond, or A and B unite together to form a vinylene group when A and B are linked by a double bond, R<sup>1</sup> is a hydrogen atom, a C<sub>l</sub>-<sub>3</sub> alkyl group or a 2-hydroxyethyl group, R<sup>2</sup> and R<sup>3</sup> are hydrogen atoms, methyl groups or ethyl groups and may be identical to or different from each other, R<sup>3</sup> may be attached to the same carbon atom as R<sup>2</sup>, R<sup>4</sup> is a methyl or ethyl group, and X is a halogen atom. The benzo-[ij]quinolizine-2-carboxylic acid derivatives and the salts, and their hydrates have good absorbability from the digestive tract into the circulating blood and exhibit excellent and long-lasting antibacterial activity.
Patent DE-3785498-T2 (DE)
Inventor: LEE VING JICK
IPC: C07C327/58
Filed: 1987-07-06
Granted: 1993-12-02
Abstract: Intermediates useful for synthesis of cephalosporins are disclosed, which intermediates are concerned with 1,2,3-thiadiazole-4-thiolates and the preparation of such thiolates.
Patent DE-3787332-T2 (DE)
Inventor: SCHUTT ERNEST G
IPC: G01N33/80
Filed: 1987-06-25
Granted: 1994-04-07
Abstract: A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio.