baber/WOPTO huggingface dataset:
Patent FI-121339-B (FI)
Inventor: KUCHERLAPATI RAJU
IPC: A01K67/027
Filed: 1995-01-23
Granted: 2010-10-15
Abstract: The subject invention provides non-human mammalian hosts characterized by inactivated endogenous Ig loci and functional human Ig loci for response to an immunogen to produce human antibodies or analogs thereof. The hosts are produced by multiple genetic modifications of embryonic cells in conjunction with breeding. Different strategies are employed for recombination of the human loci randomly or at analogous host loci. Chimeric and transgenic mammals, particularly mice, are provided, having stably integrated large, xenogeneic DNA segments. The segments are introduced by fusion with yeast spheroplasts comprising yeast artificial chromosomes (YACs) which include the xenogeneic DNA segments and a selective marker such as HPRT, and embryonic stem cells.
Patent FI-110098-B (FI)
Inventor: JOHANSSON INGEGAERD
IPC: A61K8/00
Filed: 1995-09-22
Granted: 2002-11-29
Abstract: PCT No. PCT/SE94/00199 Sec. 371 Date Nov. 14, 1995 Sec. 102(e) Date Nov. 14, 1995 PCT Filed Mar. 10, 1994 PCT Pub. No. WO94/21655 PCT Pub. Date Sep. 29, 1994   <IMAGE>  (I)  In an alkyl glucoside of formula (I) R1 is an alkyl group having 2-5 carbon atoms, preferably 2-4 carbon atom; R2 is an alkyl group having 4-7 carbon atoms, preferably 5 or 6 carbon atoms, the sum of the carbon atoms in R1 and R2 being 7-11, preferably 7-9; G is a monosaccharide residue; and x is 1-4, preferably 1 or 2. The use of the alkyl glucoside as a surfactant in a cleaning composition is also disclosed.
Patent HU-207924-B (HU)
Inventor: LINDSEY MARVIN
IPC: A01H5/10
Filed: 1990-03-12
Abstract: A találmány tárgya DE 0708 fajtajelű beltenyésztett kukoricavonal, amely a 0643 x LH38 vonalak keresztezésből származik, és amelynél a virágzás kezdete közepes, a portok antociános elszíneződése hiányzik vagy nagyon gyenge, zárt antociános gyűrű van a portok tövén, a csomók antociános elszíneződése hiányzik vagy nagyon gyenge, a csomóközök antociános elszíneződése hiányzik vagy nagyon gyenge, a burok antociános elszíneződése közepes, a burok szőrössége közepes, a címer főtengely és oldalsó elágazások szöge nagy, a primer elágazások száma kevés, a legalsó oldalág feletti főtengely hosszú, a cső nyele hosszú, a cső hosszú és hengeres, átmérője közepes, a magsorok száma kevés, a mag lófogú, csúcsa sárga, hátoldala narancssárga, amelynél a bajusz megjelenési ideje korábbi mint az M017 jelű vonalnál, előnyösen a 70-85. nap, a bajusz megjelenése és az érés közötti idő rövidebb mint a M017 jelű vonalnál, előnyösen az 50-65. nap, a növény alacsonyabb, mint a M017 jelű vonal, előnyösen 210-225 cm, a cső illeszkedési magassága alacsonyabb mint az M017 jelű vonalnál, előnyösen 70-85 cm, a levél felálló és hosszabb mint az M017 jelű vonalnál, előnyösen 80-90 cm, a sikér színe fehér, a bajusz antociános elszíneződése gyenge, a csutka antociános elszíneződése erős. HU 207 924 B A leírás terjedelme: 8 oldal (ezen belül 2 lap ábra)
Patent HU-209071-B (HU)
Title: Filtering apparatus
Inventor: BODAS SANDOR
IPC: B01D24/00
Filed: 1990-03-14
Abstract: Inside the main filter is a rotating chamber with filter discs and at least one washing utensil is placed between each filter disc.
Patent HU-202396-B (HU)
Title: Echo-impulse testing set
Inventor: KUUS MATI JUKHANOVICH
IPC: A61B8/00
Filed: 1987-11-20
Abstract: An echo-pulse tester comprises a synchronizer (5), one output of which is connected to one of the inputs of an indicating unit (9) and another input is connected to the input of a pulse generator (1). The output of the pulse generator (1) is connected to the input of an amplifier (4) and to one of the inputs of a filter (2), whose other input is connected to an ultrasonic converter (3) and the output is connected to an electronic switch (6) connected to a controlling input of a power supply unit (8). The output of the power supply unit (8) is connected to the corresponding inputs of the pulse generator (1), of the amplifier (4) and of the indicating unit (9). The tester is provided with a decimal echo-pulse counter (7) and with a pregnancy-determining circuit (10), the input of the amplifier (4) being connected to the corresponding inputs of the pregnancy-determining circuit (10) and of the echo-pulse counter (7), the outputs of which are connected to information inputs of the indicating unit (9). The output of the indicating unit (9) is connected to the other input of the pregnancy-determining circuit (10), the output of which is connected to the other input of the amplifier (4), whereas the other output of the synchronizer (5) is connected to one of the inputs of the echo-pulse counter (7), and the output of the power supply unit (7) is connected to the corresponding inputs of the echo-pulse counter (7) and of the pregnancy-determining circuit (10).
Patent HU-204042-B (HU)
Inventor: SCHNEIDER CLAUS
IPC: C07D277/82
Filed: 1987-06-19
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von Tetrahydro-benzothiazolen. Erfindungsgemaess werden Verbindungen der Formel (I) hergestellt, in der n fuer 1, 2 oder 3 steht, R1 H, F, Cl, Br, CH3, C2H5, OCH3, OC2H5, OH, CF3, R2 H, Cl, CH3, OCH3, OC2H5, OH, R3 H, NH2, R4 H, CH3, C2H5, R5 und R6 H, C1C4-Alkyl, phenylsubstituiertes C1C3-Alkyl, Allyl, Propargyl bedeuten und ihre sAeureadditionssalze, Formel (I)
Patent HU-205141-B (HU)
Title: Process for producing peptide boronic acid derivatives inhibiting trypsin-like protease, as well as pharmaceutical compositions comprising such compounds as active ingredient
Inventor: KETTNER CHARLES ADRIAN
IPC: C07K5/10
Filed: 1988-06-03
Abstract: Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, of the formula
      are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
Patent HU-189118-B (HU)
Inventor: IVANOVSKI PAVLE
IPC: B01J3/02
Filed: 1984-08-02
Abstract: Die Erfindung betrifft eine Einrichtung zum Verschliessen einer Beschickungsoeffnung von druckfesten Behaeltern, insbesondere Autoklaven, mit einem in das Innere des Behaelters absenkbaren Deckel, dessen aeusserer Durchmesser den lichten Durchmesser der Beschickungsoeffnung uebersteigt, und einer Antriebseinrichtung fuer das Oeffnen und Schliessen des Deckels. Waehrend es Ziel der Erfindung ist, die Gebrauchswerteigenschaften derartiger Verschliesseinrichtungen auf kostenguenstige Weise zu erhoehen, besteht die Aufgabe der Erfindung darin, eine robuste und sichere Einrichtung zum Verschliessen einer Beschickungsoeffnung von druckfesten Behaeltern, insbesondere Autoklaven, zu schaffen, die gewaehrleistet, dass die fuer die Fuellung des Behaelters erforderliche Fuellzeit verkuerzt werden kann. Erfindungsgemaess wird die Aufgabe derart geloest, dass der Deckel am Rand der Beschickungsoeffnung nach innen schwenkbar angelegt ist, dass die Antriebseinrichtung an der Aussenseite des Behaelters selbst abgestuetzt ist und durch wenigstens ein Zugelement mit dem Deckel verbunden ist und dass an der Beschickungsschurre oberhalb der Beschickungsoeffnung eine Umlenkeinrichtung fuer das Zugelement abgestuetzt ist. Fig. 1
Patent HU-182823-B (HU)
Inventor: OSVATH PETER
IPC: H02M5/02
Filed: 1981-12-03
Abstract: A találmány szerinti áramváltó vasmagon (vasmagokon) elhelyezett primer tekercset (tekercseket), szekunder tekercset (tekercseket) és indikátor-tekercseket tartalmaz, ahol az i indikátortekercsre a passzív kompenzáló hálózat bemeI nete kapcsolódik, amelynek kimenete DC-erősítő egyik bemenetére van kötve, továbbá a DC-erősítő kimenete közvetve vagy közvetlenül a szekunder tekercsre kap- 1 csolódik, valamint a DC-erősítő kimenete és másik bemenete közé auto-zéro áramkör kapcsolódik.  -1-
Patent HU-214009-B (HU)
Inventor: SCHENK CORNELIS
IPC: C10N40/08
Filed: 1991-12-10
Abstract: (57) KIVONAT A találmány tárgya eljárás őlyan alkenil-szűkcinimid-származékőkelőállítására, amelyeknek alkenilcsőpőrtja egy lényegében az (I)általánős képletnek megfelelő ataktikűs prőpi én őligőmerbőlszármazik, a képletben n értéke 15 és 120 közötti, a vegyület számszerinti átlagős mőlekűlatömege 700–5000, a bőrőstyánkősav egységekaránya az ataktikűs prőpilén őligőmerhez 1 : 1 és 1,5 : 1 közötti, ésa szűkcinimid egy (II) általánős képletű pőliaminból származó – aképletben m értéke 1–9, p értéke 2–4. A találmány szerint egy (I)általánős képletű ataktikűs prőpilén őligő ert maleinsavanhidriddelreagáltatnak, majd a kapőtt szűkcinált prőpilén őligőmert (II)általánős képletű pőliaminnal reagáltatják. A találmány tárgyátképezik még a fenti adalékőkat tartalmazó kenőa yag-készítmények is. ŕ
Patent HU-192950-B (HU)
Inventor: ROGACS JOZSEF
IPC: C08L23/06
Filed: 1982-12-11
Abstract: A találmány szerinti kompozíció 69-99 tömegX polietilént és/vagy polietilén hulladékot, adott esetben legfeljebb 2 tömeg% ultraibolya fénystabilizátort és 0-30 tömeg% töltő-, szivósságnöveló és egyéb segédanyagot tartalmaz. A találmány szerinti kompozíciót az jellemzi, hogy az előbbi komponenseken kívül még 0,1-10 tömeg%, előnyösen 1-3 tömeg% legfeljebb 200 μ szemcseméretü, adott esetben 200 és 500 °C közötti hőfokon víztelenített természetes és/vagy mesterséges zeolitot és 0,1-2 tömeg% elsődleges, vagy elsődleges és másodlagos antioxidánst is tartalmaz. 192950 -1-
Patent HU-206601-B (HU)
Title: Herbicide, insecticide and acaricide composition containing 3-aryl-pyrrolidine-2,4-dion derivatives and process for producing these compounds
Inventor: FISCHER REINER
IPC: A61K31/55
Filed: 1989-08-18
Abstract: New 3-arylpyrrolidine-2,4-diones of the formula (I) …<IMAGE>… are made available… in which… X stands for hydrogen, alkyl, halogen or alkoxy,… Y stands for hydrogen, alkyl, halogen, alkoxy or haloalkyl,… Z stands for alkyl, halogen or alkoxy,… m stands for a number from 1-4,… n stands for a number from 0-3, and… R stands for hydrogen or for the groups… -CO-R<1>, -CO-O-R<2>… where R<1> and R<2> have the meanings indicated in the application text. …<??>The compounds according to the invention have a strongly pronounced herbicidal and acaricidal activity.
Patent HU-203901-B (HU)
Title: Composition for producing soft pvc products of high heat-stability
Inventor: JENEK ATTILA
IPC: C08F114/06
Filed: 1988-12-14
Abstract: A compsn. for the prepn. of plasticised heat-stable PVC articles contains PVC, plasticiser heat stabilisers, epoxidised vegetable oils, known opt. additives pref. foaming agents flow improvers, antioxidants, antistatic agents and/or fillers. - Based on total compsn. wt.it contains 0.2-10 wt% heat stabilising mixt. comprising all inorganic or organic lead cpd. and a calcium salt of a carboxylic acid, in wt. ratio of (20:0.1)-(1:10).
Patent HU-203345-B (HU)
Title: Process for producing ergoline derivatives and pharmaceutical compositions comprising same
Inventor: COHEN MARLENE LOIS
IPC: C07D457/06
Filed: 1989-12-13
Abstract: (8β)-N-heteroalkyl-1- alkyl-6-(substituted) ergoline-8-carboxamides of the formula
      wherein: 
R¹ is C₁-C₄ alkyl; 
R² is allyl or C₁-C₄ straight chain alkyl; 
R³ is hydrogen or C₁-C₄ straight chain alkyl; 
R⁴ is pyridinyl or imidazolyl; 
alk is a divalent organic radical derived from a straight or branched C₁-C₅ alkane; or 
a pharmaceutically acceptable acid addition salt thereof. 
The compounds are useful for blocking 5HT₂ receptors in mammals having an excess of serotonin centrally or peripherally
Patent IT-1242636-B (IT)
Title: Sheet manipulator unit
Inventor: BOSETTI RENZO
IPC: B41M/
Filed: 1990-09-13
Granted: 1994-05-16
Abstract: The subject of this invention is a manipulator unit for sheets on which data have been printed, on the user's request. It consists of two printing machines, 6 and 7, housed in a bearing structure 1 and positioned one opposite the other, operating alternatively to one another piloted by a computer and distributing compiled sheets on the same station 10, of a marking component 41, and of a translator component 33 suitable for overturning and conveying the sheets ordered in a holder 40. <IMAGE>
Patent IT-1242301-B (IT)
Title: Universal distiller of various liquids including sea water
Inventor: CANNEDDU ANTONIO
IPC: B01D/
Filed: 1990-09-24
Granted: 1994-03-04
Abstract: Universal distiller of various liquids including sea water characterized by the fact that, suitably "controlled", it reproduces the natural water cycle (evaporation, condensation, precipitation, etc.) automatically. It has uses in a variety of fields (food, hydroelectric power, agriculture, ecology, chemistry) and, in its apparatus, with the use of various materials and prior calculations for dimensioning and optimal positioning of each component, it essentially comprises a sealed vacuum vessel with corresponding admission and discharge valves, from which a system of lines and a system for condensation of the evaporated liquid departs with ease of collection and therefore use. <IMAGE>
Patent IT-1241948-B (IT)
Title: Device for generating vibrations, particularly suitable for use with a shaking device.
Inventor: VERDEGIGLIO SANTE
IPC: A01D46/00
Filed: 1990-01-19
Granted: 1994-02-01
Abstract: The device for generating vibrations consists of two eccentric masses which rotate about non-coaxial shafts at the same or at different - or at any rate variable - speeds. This makes it possible to produce a broad range of vibrations of various types, forms and frequencies by means of which all the fruits hanging from a tree can oscillate in resonance. The shaking device in which the vibration generator is employed is particularly suitable for use on olive, almond and other similar fruit trees. For references see Fig. 5a.
Patent IT-1226170-B (IT)
Title: Chromium electrode position from trivalent chromium bath
Inventor: TARDY RENE
IPC: C23C/
Filed: 1981-01-27
Granted: 1990-12-20
Abstract: Chromium is electrodeposited from a trivalent chromium bath which is formed by dilution with water of a soln. obtd. by controlled redn. of chromic acid in a sulphuric medium by a large excess of an alcohol reducing agent such as methanol. Electrodeposition is effected, without addn. of other bath components and without using separate anode and cathode compartments, at above 6V and at 10-40A/sq. dm. cathode current density. The bath pref. contains 0.1-1 g-ion/l trivalent Cr and the anode is pref. made of a metal (e.g. Pt or Ni) which inhibits hexavalent Cr formation by anodic oxidn. Bath preparation is simple and inexpensive. The bath gives improved current efficiency (greater than 30%), has a low Cr content so that Cr losses by drag out and bath disposal are reduced and presents reduced toxicity and effluent disposal problems. Complex articles can be plated. The bath can give thick bright deposits and can plate a wide variety of material, esp. Zn. The bath can be prepared from spent hexavalent chromium baths.
Patent LV-14831-B (LV)
Title: Ex vivo diagnostic method of pulmonary cancer by analyzing exhaled air with artificial olfactory sensor
Inventor: BUKOVSKIS MĀRIS
IPC: G01N33/497
Filed: 2014-01-21
Abstract: Invention relates to lung cancer ex vivo diagnostic method using the exhaled gas analysis by electronic olfactory sensor. Proposed process provides for the exhaled gas analysis and analysis of the resulting data by mathematical methods. The process accuracy exceeds 90%.
Patent LV-11884-B (LV)
Title: Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability
Inventor: OLBRICH MATTHIAS
IPC: A61K47/14
Filed: 1997-05-14
Abstract: The invention relates to formulations of cyclosporin with high bioavailability for oral administration, which contain about 1 part by weight of one or more cyclosporin(s), preferably cyclosporin A and/or cyclosporin G, 7.5 to 7.8 parts by weight of one or more polyethylene glycol esters of saturated C10-C22hydroxy fatty acids, 0.7 to 0.85 part by weight of a monohydric alcohol as co-solvent, and 0.7 to 0.8 part by weight of a polyhydric alcohol as co-solvent. The drug form is produced by initially dissolving the cyclosporin in ethanol and, while stirring, adding propylene glycol and SOLUTOL(R) HS 15 until a clear, viscous solution results, bottled as drinkable solution or packed into capsules.
Patent ME-01781-B (ME)
Title: Process for the preparation of rosuvastatin
Inventor: Fischer János 
IPC: C07D405/06
Filed: 2006-05-26
Abstract: The subject of the present invention is a process for the preparation of rosuvastatin by reacting a compound of formula (II), by alkalic hydrolysis to give a compound of formula (III), thereafter reacting with an organic or inorganic base to form a salt, eliminating the acetonide group and reacting with calcium-chloride in a base. A further subject of the present invention is a compound of formula (III) and its salts formed by organic or inorganic base.
Patent MX-170813-B (MX)
Title: Procedimiento y sistema para la produccion de poliester de alto peso molecular
Inventor: SCHULZ VAN ENDERT EIKE
IPC: C08G63/78
Filed: 1987-04-21
Abstract: La presente invención se refiere a procedimiento para la producción de poliester de alto peso molecular en el cual produce una masa que puede bombearse y que está constituida particularmente por ácido terfáltico y diol alquileno, que se esterifica y luego policondensada al vacío en por lo menos un reactor de vacío en conjunto reactor de dos o más fases, caracterizado porque la generación del vacío para por lo menos un reactor de vacío por medio del calor de escape del conjunto reactor.
Patent MX-166923-B (MX)
Title: Metodo mejorado para tratar corrientes que tienen mercaptano o dompuestos a base de mercaptano
Inventor: LE BINH NGOC
IPC: C10G19/02
Filed: 1987-06-16
Abstract: La presente invención se refiere a un método para tratar una primera corriente, que contiene mercaptanos o compuestos a base de mercaptanos, por medio del contacto de esta primera corriente con una segunda corriente, en el cual los mercaptanos o compuestos a base de mercaptanos son o extraídos, u oxidados catalíticamente a compuestos de disulfuro, o ambos, en que la primera corriente es o un destilado de hidrocarburos agrios (sulfurosos) o una solución cáustica gastada; con la condición que si la primera corrientes es un destilado de hidrocarburos agrios, la segunda corriente es una solución cáustica, y si la primera orriente es una solución cáustica gastada, la segunda corriente es un destilado de hidrocarburos, caracterizado porque se ponen en contacto la primera y segunda corrientes en la preencia de alrededor de 1 ppm a unas 50 ppm, en peso, con base en el peso de la coriiente de hidrocarburos, de un promotor a base de nitrógeno, que comprende un compuesto orgánico substancialmente exento de azufre, no electrolítico, que tiene al menos un átomo de nitrógeno, este promotor a base de nitrógeno se selecciona del grupo que consta de: compuestos
Patent NO-147349-B (NO)
Title: Varmegjenvinningsanlegg.
Inventor: ROSENBERG JAN
IPC: F28F/
Filed: 1980-02-12
Abstract: Ved varmegj.envinningsanlegg (1) arbeider man med både fraluft. og tilluft, og her kan det ved lave utetemperaturer oppstå ned-isingsproblemer i selve den varmevekslende delen (5 og 6) av et anlegg (1). For å unngå nedising, oppvarmes tilluften før varmeveksling. For å styre oppvarmingen, finnes organ som føler tilluftens temperatur etter varmeveksling, og på basis av nevnte føling bedømmes temperaturen av den fraluft som kan utsettes for isdannelse. Ifølge foreliggende oppfinnelse derimot, plasseres et organ (17 resp. 18) som føler temperaturen av forbistrømmende luft og som påvirker oppvarmingen på en slik måte at fraluften etter varmeveksling med tilluften påvirker sistnevnte organ (17 resp. 18) på en slik måte at når risiko for nedising av fraluften foreligger, startes oppvarming av tilluften.
Patent NO-160367-B (NO)
Inventor: WINTERS GIORGIO
IPC: A61K31/44
Filed: 1983-12-19
Abstract: The present invention is directed to new 4,7-dihydro-pyrazolo[3,4-b]pyridines. The compounds possess Ca2+-antagonist, antihypertensive, vasodilating and antiangina activity. A process for producing them as well as pharmaceutical compositions containing them are also described.
Patent NO-174522-B (NO)
Title: Broennverktoey
Inventor: AKKERMAN NEIL HOOVER
IPC: E21B23/02
Filed: 1984-04-25
Abstract: Brønnutstyr innbefattende et brønnverktøy (21) beregnet til å senkes ned i og låses til en landingsnippel (20) i en borestreng, sammen med et vaierverktøy (22), som kan forbindes med brønnverktøyet for nedsenking av det til låse-stillingen og låsing i nippelen, hvoretter vaierverktøyet frigjøres fra brønnverktøyet.
Patent NO-163202-B (NO)
Inventor: GOEBEL KONRAD
IPC: F02C6/14
Filed: 1984-05-23
Abstract: Medium-load power generating plant with an integrated coal gasification plant, with a gas-turbine power generating plant part connected to the coal gasification plant, with a steam generating plant part connected to the raw-gas heat exchanger installation of the coal gasification plant, and with a methanol synthesis plant. The methanol synthesis plant has parallel-connected modules and is connected to the gas-turbine power generating plant part via a central purified gas distribution system which includes a purified gas continuous-flow interim storage plant connected parallel to the pure gas supply line and is connected on the gas side to the raw-gas heat exchanger installation.
Patent NO-161227-B (NO)
Inventor: KIEZLING GERHARD
IPC: H01B3/42
Filed: 1984-07-18
Abstract: 1. Impregnation materials consisting of unsaturated polyesters and acryloyl and/or methacryloyl compounds as reactive diluents and optionally conventional additives, characterised in that they contain a) hexanediol diacrylate and/or b) butanediol diacrylate as reactive diluents and in that the viscosity of the impregnation materials is at the most 1500 mPa . s.
Patent NO-159537-B (NO)
Inventor: SELVA ENRICO
IPC: C12P1/06
Filed: 1984-08-30
Abstract: The present invention concerns a new antibiotic substance arbitrarily designated as antibiotic SB 22484, a process for its production by culturing Streptomyces sp. NRRL 15496 or a producing variant or mutant thereof, and the use of the new antibiotic substance in the treatment of infectious diseases involving microorganisms susceptible to this antibiotic substance such as Neisseriae strains.
Patent NO-180786-B (NO)
Inventor: BRAUN PETER BERNHARD
IPC: E05B27/00
Filed: 1989-08-15
Abstract: A locking device comprises a lock cylinder (1) and a reversible flat key (2) having indentations (26) located on opposite broad faces (24) of the key for the arrangement of tumbler pins (17), and having a rib (25) associated with each row of indentations, into the sectional area of which at least one of the pins (17) extends and the crest (25 min ) of which rib (25) projects beyond the broad face (24) of the key. The deepest reached indentation (26) lies nearest to the crest (25 min ) of the rib (25) and several indentations (26) of a row of indentations are integrated into a through groove (N) of variable depth levels (27, 28, 29, 30).
Patent NO-177301-B (NO)
Inventor: STRUPCZEWSKI JOSEPH T
IPC: C07D413/04
Filed: 1990-05-18
Abstract: This invention related to compounds of the formula: <CHEM>  wherein  X is -O-, -S-, - @H, or -@-R<2>;  p is 1 or 2; Y is hydrogen, C1 to C6 alkyl, -OH, Cl, F, Br, I, C1 to C6 alkoxy, -CF3, NO2, or -NH2, when p is 1;  Y is C1 to C6 alkoxy when p is 2 and X is -O-; R<2> is selected from the group consisting of lower alkyl, aryl lower alkyl, aryl, cycloalkyl, aroyl, alkanoyl, and phenyl sulfonyl groups;  Z is -CH- or -N-;  n is 2, 3, 4, or 5; R is hydrogen, alkyl, C1 - C6-alkoxy, hydroxyl, carboxyl, Cl, F, Br, I, amino, C1 - C6-mono or-dialryl amino, -NO2, lower alkyl thiol -OCF3, cyano, acylamino, -CF3, trifluoroacetyl, aminocarbonyl, <CHEM>  where  alkyl is lower alkyl;  aryl is phenyl or <CHEM> R1 is hydrogen, lower alkyl, C1 - C6 alkoxy, hydroxy, Cl, F, Br, I, C1 - C6 alkyl amino, -NO2, -CN, -CF3, -OCF3; and  heteroaryl is <CHEM>  where  Q is -O-, -S-, - @H, -CH=N;  R3 is hydrogen, lower alkyl, or acyl; and  m is 1, 2, or 3;  or a pharmaceutically acceptable acid addition salt thereof. The invention relates further to a process for the preparation of the above compounds and their use as medicaments having antipsychotic and/or analgetic activity.