baber/WOPTO huggingface dataset:
Patent CY-1124890-T1 (CY)
Title: Συστηματα και μεθοδοι χορηγησης φαρμακων για θεραπεια καρκινου της ουροδοχου κυστης που περιλαμβανουν οξαλιπλατινη
Inventor: GIESING DENNIS
IPC: A61K31/555
Filed: 2022-01-05
Abstract: Μέθοδοι, συσκευές και φάρμακα που περιλαμβάνουν οξαλιπλατίνη παρέχονται για χρήση στη θεραπεία του καρκίνου της ουροδόχου κύστης με τοπική χορήγηση οξαλιπλατίνης στην ουροδόχο κύστη ενός ασθενούς για την επίτευξη μιας παρατεταμένης συγκέντρωσης οξαλιπλατίνης στα ούρα στην ουροδόχο κύστη επαρκή για την παραγωγή θεραπευτικής συγκέντρωσης οξαλιπλατίνης στον ιστό της ουροδόχου κύστης. Η οξαλιπλατίνη μπορεί να χορηγηθεί στην ουροδόχο κύστη από μια συσκευή ενδοκυστικής χορήγησης φαρμάκου που έχει εισαχθεί στην ουροδόχο κύστη, όπου η συσκευή απελευθερώνει συνεχώς την οξαλιπλατίνη στα ούρα στην ουροδόχο κύστη για μια εκτεταμένη περίοδο ωρών ή ημερών.
Patent HR-P20120175-T1 (HR)
Inventor: STEVENS SEAN
IPC: C12N15/13
Filed: 2012-02-22
Abstract: Antitijelo ili njegov fragment koji se veže na antigen, koji se specifično veže na humani interleukin-6 receptor (hIL-6R) s konstantom KD od 500 pM ili manjom izmjereno površinskom plazmonskom rezonancijom, naznačeno time, da CDR teškog lanca i CDR lakog lanca sadržavaju: (i)	SEQ ID NO: 21, 23 i 25 kao regije CDR1, CDR2 i CDR3 teškog lanca te SEQ ID NO: 29, 31 i 33 kao regije CDR1, CDR2 i CDR3 lakog lanca; ili (ii)	SEQ ID NO: 149, 151 i 153 kao regije CDR1, CDR2 i CDR3 teškog lanca te SEQ ID NO: 157, 159 i 161 kao regije CDR1, CDR2 i CDR3 lakog lanca. Patent sadrži još 12 patentnih zahtjeva.
Patent SI-1451416-T1 (SI)
Title: Liquid active substance dispenser for w.c. bowl
Inventor: PAGANI FABIO
IPC: E03D9/03
Filed: 2002-10-21
Abstract: The dispenser comprises a bottle ( 11 ) for containing the active substance (R) in the liquid state and provided with an exit mouth ( 12 ) for the active substance (R), and a support means ( 20 ) for supporting said bottle ( 11 ) in an inverted position, in a position subjected to the action of the flushing water flow. The support means ( 20 comprises, for containing the active substance, a reservoir ( 21 ) located in a position subjected to the action of the flushing water flow and arranged to receive the mouth ( 12 ) of the bottle, and a member ( 30 ) positioned in said containing reservoir ( 21 ) to close the mouth ( 12 ) of the bottle ( 11 ); there is also provided for the active substance at least one passageway associated with said closure member ( 30 ) to enable the active substance to pass from the internal chamber of the bottle ( 11 ) to the containing reservoir ( 21 ). The containing reservoir ( 21 ) defines a volume for containing a quantity of active substance which closes said passageway for the active substance.
Patent SI-1388697-T1 (SI)
Title: Safety device with automatic activation
Inventor: DELPRAT CYRILLE
IPC: F16L55/132
Filed: 2003-07-24
Abstract: Safety device includes annular obturator (4) mounted on external periphery of tube (1). Obturator is radially separated from pipe (K) by annular space (EA) which offers to gas a peripheral flowpath. As soon as flowrate in pipe reaches high levels, obturator is radially bulges out, due to important energy loss of gas in movement, and obturator blocks off peripheral flowpath.
Patent SI-1601480-T1 (SI)
Title: Die-casting machine
Inventor: THIBAULT CARL
IPC: B22D17/00
Filed: 2003-02-13
Abstract: An injection unit for a hot-chamber die-casting machine has an injection portion with a gooseneck and a nozzle adaptor. The injector portion has a base portion at an end of the gooseneck adapted to receive a molten medium supply. A nozzle at an end of the nozzle adaptor is adapted to inject the molten medium supply in a die cavity. A channel between the base portion and nozzle is adapted to convey the molten medium supply therethrough. A piston chamber in the base portion is actuatable to draw the molten medium supply therein and to direct the molten medium supply in the channel for injection into the die cavity. An actuation portion is connected to the gooseneck to actuate the piston chamber. Heating cartridges are received in the injection portion adjacent to the channel to control temperature of the molten medium supply in the channel.
Patent SI-1506095-T1 (SI)
Title: Value document and method and device for the production thereof
Inventor: ECKARDT MONIKA
IPC: B42D15/00
Filed: 2003-05-07
Abstract: The invention relates to a paper of value ( 1 ) with at least one security feature ( 3 ), in particular a bank note ( 1 ), as well as a method and an apparatus for producing such a paper of value ( 1 ). By virtue of e.g. bank notes ( 1 ) being produced with at least one rounded corner area ( 4 a-d, 4 a'-d'), the likelihood of the formation of dog-ears and thus of jams during automatic tests in bank note processing machines is reduced.
Patent SI-1694360-T1 (SI)
Title: Use of antagonist anti-cd40 antibodies for treatment of autoimmune and inflammatory diseases and organ transplant rejection
Inventor: LONG LI
IPC: C07K16/18
Filed: 2004-11-04
Abstract: Methods of treating a subject for a cancer comprising neoplastic cells expressing the CD40 cell surface antigen are provided. The methods comprise combination therapy with interleukin-2 (IL-2) or biologically active variant thereof and at least one antagonist anti-CD40 antibody or antigen-binding fragment thereof. In some embodiments, these two therapeutic agents are concurrently administered as two separate pharmaceutical compositions, one containing IL-2 or biologically active variant thereof, which is administered according to a constant IL-2 dosing regimen or a two-level IL-2 dosing regimen, the other containing the antagonist anti-CD40 antibody or suitable antigen binding fragment thereof, which is administered according to a weekly dosing regimen, or alternatively is dosed once every two, three, or four weeks.; Administering of these two agents together potentiates their effectiveness in promoting a positive therapeutic response. The methods find use in treating CD40-expressing cancers, including B-cell related cancers and solid tumors.
Patent SI-1638551-T1 (SI)
Title: Immunosuppressant compounds and compositions
Inventor: MARSILJE THOMAS H
IPC: A61K31/216
Filed: 2004-05-19
Abstract: The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particularly diseases associated with EDG receptor mediated signal transduction.
Patent SI-1733042-T1 (SI)
Title: Chemo-enzymatic process for preparing escitalopram
Inventor: COTTICELLI GIOVANNI
IPC: C12P41/00
Filed: 2005-04-07
Abstract: A process for preparing an intermediate for synthesizing escitalopram and the pharmaceutically acceptable salts thereof from 4-(4-dimethylamino)-1-(4'-fluorophenyl)-1-(hydroxybutyl)-3-(acyloxymethyl)benzonitrile is described. The process involves converting said intermediate into the (S+) enantiomer of citalopram by means of enzymatic enantiomeric resolution.
Patent SI-2018153-T1 (SI)
Title: Liquid oral compositions
Inventor: DRIVER PHILLIP
IPC: A61K9/00
Filed: 2007-04-26
Abstract: Aqueous suspensions for oral administration are disclosed that include simvastatin having a d90 of simvastatin particles of less than about 100 μm as the active agent. The aqueous suspension also includes simvastatin as about 20 mg to about 80 mg per 5 ml of the aqueous suspension, a suspending agent as about 20 mg to about 50 mg of the aqueous suspension, a wetting agent, an antimicrobial preservative, an antifoaming agent, water, and a buffering system providing the aqueous suspension with a pH of about 6.4 to about 7. Methods of making such a suspension and methods of treatments in orally administering the same are also disclosed.
Patent TR-200904939-T1 (TR)
Title: Genellikle kontrollü ortamlarda deri veya benzeri kurutma tesisleri veya işleme tesisleri için bindirme taşıyıcı bantlı taşıyıcı aparatı.
Inventor: MARINO VITO
IPC: C14B17/06
Filed: 2006-12-28
Abstract: Genellikle deri veya benzeri ürünler için kullanılan bir kurutma veya işleme tesisi, ürünlerin bantlann besleme hareketinin mükemmel senkronizasyonu ve bantlann enine germe araçlanyla birleşen transmisyon zincirlerinin birleşmesi sayesinde bir yükleme istasyonuyla bir boşaltma istasyonu arasmda bulunan işleme bölmesinin içinde hareket ettikleri iki bant arasında düz bir konumda tutulduğu bindirme taşıyıcı bantlan olan bir taşıyıcı aparat temin etmesidir. İki bandın transmisyon zincirleri, yükleme ve boşaltma istasyonlanna yaklaştıklannda iki bandı kolayca ayırmaya ve daha sonra bunlan tekrar üst üste bindirmeye olanak sağlayacak şekilde şekillendirilir.
Patent DE-3751142-T2 (DE)
Inventor: BRUNNER ADOLF
IPC: A63B59/12
Filed: 1987-05-18
Granted: 1995-11-30
Abstract: An apparatus for programming and controlling the seizing of a handle of a ball-hitting instrument and the guiding of the instrument by a player during striking of a ball in a ball game, comprising      an apparatus casing (120) a housing therein for a source (5) of electric direct current and  an electronic circuit mounted in said casing having a circuit board (4), on-off-switch means (6), an integrated circuit chip means (20;127), preferably a single-chip microprocessor, switching and control means (7,17,12,22;129,131,135,139,142) adapted to respond to the entire rhytm of the sequence of movements of the ball-hitting instrument, means for programming the motional sequence of the entire rhytmics of the ball-hitting instrument, means for controlling the run-off of the program, and means (9,133) for producing an easily noticeable signal indicating at least one of the correct and incorrect motional sequences of the entire rhytmics of the ball-hitting instrument, whereby the complete sequence of motional phases during forehand play, backhand play and service of a ball with the aid of a bat can be programmed as well as controlled by comparison with a master program produced with the above apparatus, independently of whether the player is right-handed or left-handed.
Patent DE-3751382-T2 (DE)
Inventor: CHAPMAN MICHAEL WILLIAM
IPC: A61F2/32
Filed: 1987-06-18
Granted: 1995-11-09
Abstract: An instrument (27) for use in inserting a surgical implant into a cavity in a patient's bone characterized in that said instrument (27) comprises:an elongated rod (21) having a first end and a second end, said rod (21) having an externally threaded portion (23) adjacent said first end and an externally smooth portion (29) extending from said externally threaded portion (23) towards said second end, and said rod (21) being axially cannulated over at least a portion of its length so as to be capable of fitting over a surgical guide wire;a hollow sleeve (31) receiving said elongated rod (21), said sleeve (31) being capable of sliding movement upon said externally smooth portion (29) of the rod (21); andmeans (35) for advancing the hollow sleeve (31) along the externally smooth portion (29) of the rod (21) towards said externally threaded portion (23),said advancing means (35) positively preventing movement of the sleeve (31) along the rod (21) in a direction away from said externally threaded portion (23) while it is engaged with the sleeve (31), whereby advancement of the sleeve (31) can be stopped without relaxing the force being placed upon it by said advancing means (35).
Patent DE-3751422-T2 (DE)
Inventor: ANDERSON JEFFREY E
IPC: G01N15/00
Filed: 1987-08-12
Granted: 1995-12-14
Abstract: The ability of mononuclear leukocytes to respond to standard stimuli is measured based on the expression of activation antigens on mononuclear cell subclasses. In a preferred embodiment, a sample of mononuclear leukocytes is cultured for up to 24 hours with a standard stimulus known to activate such cells. After culturing, aliquots of the cells are incubated with fluorophore-conjugated monoclonal antibodies to antigenic determinants of a particular mononuclear subclass and different fluorophore-conjugated monoclonal antibodies to particular activation antigens. The incubated aliquots are analyzed on a flow cytofluorometer, whereby each cell is illuminated with a particular light (e.g. argon ion laser), which detects and measures forward light scatter, orthogonal light scatter and two different wavelengths of light emitted from the fluorophores. These parameters are used to identify and enumerate the cells of different subclasses present within the mononuclear leukocyte sample, the cells of said subclasses which have been induced to express a particular activation antigen and the quantity of the activation antigen on said cells. An analysis of these enumerations is shown to correlate with the immunoregulatory status of the mononuclear leukocyte immune system. Data generation and analysis can be performed using a flow cytofluorometric apparatus with data and control signal processing to ensure accuracy and reproducibility of the results of the assay.
Patent DE-3751963-T2 (DE)
Inventor: BEDBROOK JOHN ROBERT
IPC: C12N15/60
Filed: 1987-08-20
Granted: 1997-05-28
Abstract: A nucleic acid fragment encoding a herbicide-resistant plant acetolactate synthase protein is disclosed. This nucleic acid fragment contains at least one nucleotide mutation resulting in one amino acid change in one of seven substantially conserved regions of acetolactate synthase amino acid homology. This mutation results in the production of an acetolactate synthase protein which is resistant to sulfonylurea herbicide compounds compared to the wild-type protein. Transformation of herbicide sensitive plants or plant cells with the fragment results in resistance to the herbicide.
Patent DE-3851532-T2 (DE)
Inventor: HAMRIN KARL-ARVID
IPC: F21V29/505
Filed: 1988-02-16
Granted: 1995-05-11
Abstract: PCT No. PCT/SE88/00060 Sec. 371 Date Aug. 16, 1989 Sec. 102(e) Date Aug. 16, 1989 PCT Filed Feb. 16, 1988 PCT Pub. No. WO88/06254 PCT Pub. Date Aug. 25, 1988.An infra-red radiator comprises a ventilated body structure (10) having a cross-web (12), a central leg (14), two side legs (16) and two intermediate support legs (18). Stretched between the legs (14, 16) are two reflectors (24) made of a flexible metal foil material and located in front of IR-lamps (26). Located between reflectors and body structure are ventilating hollows or cavities (36, 38) and channels (40, 57), for cooling or ventilation air, are incorporated in the legs. Inlet channels (40) have upper openings (44) which project cooling air flow along with the rearwardly located surface of the reflector (24), and lower openings (46) which project cooling air flow (52) along the reflector surface located between the reflector (24) and lamp (26). Turbulent cooling air (58) flows in the hollows (36, 38) behind the reflector (24) and passes from inlet openings (54), via laterally offset channels (46) in the support legs (18), to the outlet channels (57) and is exhausted, via openings (50), in the form of a jet or pilot flow (68) which, as a result of an ejector effect, accelerates and amplifies the cooling air flow (52).
Patent DE-3876434-T2 (DE)
Inventor: SPANKE ANTHONY
IPC: H04B10/27
Filed: 1988-02-29
Granted: 1993-04-01
Abstract: Optical switch networks and the design rules for creating them are disclosed. The networks comprise a plurality of input and output stages of optical switch elements. Each input optical switch stage is comprised of a plurality of 1 by 2 optical switch elements and each output stage is comprised of a plurality of 2 by 1 optical switch elements. Using these stages, optical switch networks are constructed where switch elements are interconnected by optical waveguides diffused in a substrate. Further, the connections between adjacent stages include optical waveguide crossovers (crossthroughs).
Patent DE-3879964-T2 (DE)
Inventor: MENDENHALL GEORGE A
IPC: B26D1/00
Filed: 1988-12-30
Granted: 1993-07-08
Abstract: A cutter blade assembly 100 for producing elongated string cuts of food product using a hydraulic cutting apparatus where the elongated string cuts produced are free from feather cuts and compression cell damage, and further have small cross-sectional areas. The cutter blade assembly 100 is constructed from a front inlet adapter plate 101 having an inner longitudinal passageway therethrough shaped to form a conical converger 102. Pyramidal knife supports 103, 104, 105 and 106, are attached in opposing pairs around conical converger 102 to the back of front inlet adapter plate 101 to form a pyramidal frame. A plurality of strip knives are attached in a staggered perpendicular interlocking arrangement to form a sequential cutting grid.
Patent TR-199800942-T2 (TR)
Inventor: GROSRIEZ CAROL LEFEBVRE DU
IPC: B31F1/07
Filed: 1996-11-29
Abstract: The present invention relates to a tissue paper sheet (1) comprising one or more plies (6, 7), each having a basis weight of approximately 12 to approximately 70g/m and a part of the surface of which is marked. According to the invention, the surface part is marked by an impressed pattern (5, 5') simulating a watermark, the impression being applied to one side of the sheet (1), the opposite side corresponding to said impression being plane, the marked surface being smooth, glossy and translucent, and the marked surface comprising at least one marked unit region wherein the ratio of the thickness thereof to the area thereof is less than 0,027. The present invention applies to the manufacture of tissue paper sheets and of disposable decorative handkerchiefs.
Patent TR-199900021-T2 (TR)
Inventor: FIST ANTHONY JOHN
IPC: A01H6/64
Filed: 1997-07-08
Abstract: The invention relates to a method for producing a stably reproducing poppy plant of Papaver somniferum having thebaine and oripavine constituting about 50% by weight or greater of the alkaloid combination consisting of morphine, codeine, thebaine and oripavine, the method comprising the steps of:a) exposing at least one poppy seed of Papaver somniferum to a mutagenizing agent,b) growing the at least one poppy seed to produce a plant bearing a leaf or an immature poppy capsule, optionally through multiple self-fertilized generations,c) sampling the leaf or poppy capsule for the presence of thebaine, oripavine, morphine and codeine, andd) repeating steps a) to c) until a poppy plant of Papaver somniferum is obtained having thebaine and oripavine constituting about 50% by weight or greater of the alkaloid combination consisting of morphine, codeine, thebaine and oripavine, and to plants obtainable by this method.
Patent TR-199901041-T2 (TR)
Inventor: WEIHBRAUCH GEORGE
IPC: A61C15/00
Filed: 1997-11-11
Abstract: En azindan bir adet, ekstrüde edilmis polimerden üretilmis bir temizlik unsuruna sahip bir dis bakim cihazinda, temizlik unsurunun polimerinin en azindan yüzeye yakin olan bölümünde, su ve/veya tükürük içerisinde çözünebilen, dislere bakim uygulayici ve/veya anti-bakteriyel etkili katki maddelerinin kati, ince dagilmis sekilde uygulanmasi önerilmektedir. Ayrica dis bakim cihazlari için, polimer eriyigine su ve/veya tükürük içerisinde çözünebilen, dise bakim uygulayici ve/veya anti-bakteriyel etkili katki maddelerinin ince dagilmis sekilde eklendigi ve karisimin esktrüde edildigi bir polimerden üretilmis temizlik unsurlarinin üretilmesine yönelik bir yöntem önerilmektedir.
Patent DE-60001414-T2 (DE)
Inventor: BURGEY S
IPC: C07D401/12
Filed: 2000-06-01
Granted: 2003-11-06
Abstract: Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure:A is wherein Y1 and Y2 are independentlyhydrogen,C1-4 alkyl,C1-4 alkoxy,FuHvC(CH2)0-1 O-, wherein u and v are either 1 or 2, provided that when u is 1, v is 2, and when u is 2, v is 1,C3-7 cycloalkyl,thio C1-4 alkyl,C1-4 sulfinylalkyl,C1-4 sulfonylalkyl,halogencyano, ortrifluoromethyl, andwherein b is 0 or 1.
Patent DE-60001491-T2 (DE)
Inventor: BRACHI MAUREEN JACQUELINE
IPC: B60R1/06
Filed: 2000-03-27
Granted: 2004-01-29
Abstract: An attachment (10) for a minor assembly (25) comprises an image reflecting member (12) secured to means (14) for coupling the reflecting member (12) to the minor assembly. The coupling means (14) is a sleeve like member to fit over the minor assembly (25). The arrangement is such that in use, when the attachment (10) is coupled to the minor assembly (25) the image reflecting member (12) is located substantially in register with a minor portion area of the minor assembly.
Patent DE-60002271-T2 (DE)
Inventor: PAXMAN NEIL ERIC
IPC: B67D1/08
Filed: 2000-09-14
Granted: 2003-11-20
Abstract: A beverage line (1) and a water line (2) exit from a Python cooling system (3) and enter a manifold (4). The beverage line (1) runs directly through the H-shaped manifold (4) to a tap (5). The water line (2) enters the manifold (4) and water flows through and exits through pipe (6) which surrounds the beverage pipe (1). Adjacent the tap (5), the water flows out of the coaxial pipe (6) and down return pipe (7) which connects into the manifold (4) at connection point (8). The water flows out of the manifold (4) through pipe (9). A bypass pipe (10) is provided in the manifold (4). This allows narrower gauge pipes to be used in the cooling loop without throttling the flow of water through the Python. A valve (11) is provided in the bypass pipe (10) allowing the flow through the bypass pipe (10) to be reduced or shut off, so that all the flow through inlet pipe (2) is directed through the cooling loop, to remove airlocks.  <IMAGE>
Patent DE-60005170-T2 (DE)
Inventor: THOMSEN WERNER
IPC: E04D3/08
Filed: 2000-04-18
Granted: 2004-07-01
Abstract: In the drainage and sealing system, an external rain shield is designed as a separate flexible sealant strip (38,58,59), and an internal drain trench (44, 64) is provided on a separate drain element (40, 60) extending in parallel to and at a distance from the external sealant strip (38, 58, 59). The drain element (40) and the external sealant strip (38) comprise a flange portion (41, 38b) for releasable securing to a frame member of a panel in the panel system. The separate drain element (40, 60) can be designed as an internal cover strip where the drain trench (44, 64) is provided in an essentially U-shaped portion (43, 63), and where the drain element on the side facing away from the drain trench (44, 64) has a portion (42, 62) for reception of an internal sealant strip (45, 65).
Patent DE-60006320-T2 (DE)
Inventor: TAKIZAWA HIROSHI
IPC: B41J15/04
Filed: 2000-07-04
Granted: 2004-09-16
Abstract: A load buffering device enables smooth roll paper transportation and minimizes the space required for its installation in the printer. The load buffering device has an arm that moves a particular angle around a shaft on which the paper roll (R) turns. A roller (23) extends widthwise to the roll paper from the arm at a point radially outside of the paper roll. Paper pulled off the roll is guided around this roller (23). When a transport roller (14) is driven to advance the paper, tension applied to the paper causes the arm via roller (23) to turn in one direction. An urging means such as a spring urges the roller (23) and arm in the opposite direction, maintaining even tension on both sides of the roller (23) and thereby enabling smooth roll paper transportation.  <IMAGE>