baber/WOPTO huggingface dataset:
Patent IL-123676-A0 (IL)
Title: Cyclosporin-containing soft capsule preparations
Inventor: WOO JONG SOO
IPC: A61K9/48
Filed: 1997-06-19
Abstract: A composition (A) comprises: (a) cyclosporin (I) as active ingredient; (b) polyethylene glycol (PEG) and/or propylene carbonate (PC); (c) an oil component consisting of a mixture of an esterified compound of fatty acid and primary alcohol, and fatty acid monoglyceride; and (d) a surfactant (HLB value 8-17). Also claimed is the preparation of the composition comprising: (i) mixing (b), (c) and (d); (ii) adding (a) with stirring and heating to 60[deg]C; and optionally (iii) encapsulating the concentrate into a gelatin shell soft capsule containing PEG and propylene glycol as the plasticiser, followed by air cooling.
Patent IL-126356-A0 (IL)
Title: Spring-powered dispensing device for medical purposes
IPC: A61M5/31
Filed: 1997-03-21
Abstract: A dispensing device, such as a needleless injector, comprising a spring, which provides an energy store, and a dispensing member movable, to effect a dispensing, under the force of the spring. A latch has a first position in which it restrains movement of the dispensing member and a second position in which it permits such movement. A trigger is operable by the user for moving the latch from the first position to the second position. A safety mechanism, preferably in the form of an appropriately shaped slot in the dispensing member, is effective before the device has been completely assembled to prevent movement of the latch to the second position.
Patent IL-129772-A0 (IL)
Title: Constrained helical peptides and methods of making same
IPC: A61P31/18
Filed: 1997-11-05
Abstract: Provided are cyclized peptides with a constrained region(s) having an alpha -helical conformation. Constrained helical peptides having amino acid sequences from HIV gp41 are provided, as is their use in preparing antibodies that prevent viral membrane fusion. Also provided are methods for making such cyclized peptides.
Patent IL-135602-A0 (IL)
Title: Determination of cellular growth abnormality
IPC: C07K/
Filed: 1998-10-21
Abstract: Methods tor determining cell growth abnormalities, particularly cancerous or pre-cancerous cells, are described in which polypeptides involved in the preinitiation complex of DNA replication are detected. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Typically antibodies detecting these proteins are used in screening assays on tissue sections or smears. The detection of RNA encoding these proteins is also described. The application is particularly concerned with cervical neoplasia's but also describes screening for growth abnormalities of breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract tissue.
Patent IL-141998-A0 (IL)
Title: Novel amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing same
IPC: C07D473/08
Filed: 1999-09-22
Abstract: Amidines (I) are new. <??>Amidines (I) of formula (I') and their salts are new. <??>A = phenyl, benzhydryl or a group of formula A1 - A9; <??>R1-R3 = halo, OH, SR6, 1-6C alkyl, 2-6C alkenyl, 1-6C alkoxy or NR6R7; <??>R4 = H or 1-6C alkyl; <??>R5 = OH, SR6, 1-6C alkyl or 1-6C alkoxy, but may not be SR6 nor alkoxy in A4; <??>R6 = H, 1-6C alkyl or 1-6C alkoxy; <??>R7 and R8 = H, OH, 1-6C alkyl or -CO-R9 but may not be alkyl nor COR9 in A5; <??>R9 = H, OH, 1-6C alkyl or 1-6C alkoxy, but may not be H, OH nor alkoxy in A1; <??>R10 and R11 = H or OH; <??>B' = 1-6C alkyl, 5-6 membered carbocyclic or heterocyclic aryl (heterocycle having 1-4 O, N, or S atoms, aryl optionally substituted by 1-6C alkyl, 1-6C alkoxy or 2-6C alkenyl) or NR13R14; <??>R13 and R14 = H or 1-6C alkyl; or <??>NR13R14 = 5 or 6 membered non-aromatic heterocycle comprising CH2, NH, O or S; <??>X = -(CH2)m-, -O-(CH2)m-, -S-(CH2)m-, -NR15-(CH2)m-, -CO-NR15-, -O-(CH2)m-CO-, -S-(CH2)m-CO-, -NR15-(CH2)m-CO- or -(CH2)m-C(OH)(CH3)-CO-; <??>Y' = -(CH2)n- or -(CH2)r-Q-(CH2)s-; <??>Q = piperazine, homopiperazine, 2-methyl piperazine, 2,5-dimethyl piperazine, piperidine, 1,2,3,6-tetrahydropiperidine, pyrrolidine, azetidine or a saturated 3-7C chain; <??>T = -(CH2)p-O-(CH2)q-, -(CH2)p-S-(CH2)q-, -(CH2)p-NR16-(CH2)q-, -(CH2)p-CO-NR16-(CH2)q-, or -CO-(CH2)p-NR16-(CH2)q-; <??>R12, R13, R14, R15, and R16 = H or 1-6C alkyl; <??>m, n, p, q, r, and s = 0-6;and <??>provided that when A = A6, then Y' is piperidine, and when A = A4, then Y' is -(CH2)r-Q-(CH2)s in which Q is a saturated 3-7 membered ring.
Patent IL-142146-A0 (IL)
Title: Method and means for drying cemented carbide and similar
IPC: C04B35/628
Filed: 1999-09-24
Abstract: The present invention relates to a powder consisting of agglomerates of cemented carbide, cermets, ceramics or similar materials with good abrasive wear resistance. The agglomerates have a distribution of size prior to any subsequent sieving with the ratio of d97/d03 < 4 where d97= the grain size below which 97 % of the agglomerates is found and d03= the grain size below which 3 % of the agglomerates is found.
Patent IL-142952-A0 (IL)
Title: Process for enzyme-catalyzed production of 1,2 diacylated phospholipids
IPC: C12P9/00
Filed: 2001-05-03
Abstract: A new enzymatic process for preparing 1,2-diacylated phospholipids using an enzyme preparation possessing phospholipase activity towards acylation at the sn-1 and sn-2 sites in a microaqueous reaction system. More particularly, the 1,2-diacyl-phospholipids produced according to the esterification/transesterification process are obtainable in high yield and purity and carry identical desired carboxylic acid, preferably fatty acid, acyl groups at the sn-1 and sn-2 positions. The process involves esterification/transesterification (acylation) of a glycerophospholipid, preferably glycerophosphoryl choline (GPC) with a desired carboxylic acid, preferably fatty acid, or their derivatives in the presence of the above mentioned appropriate enzyme preparation. The process of the invention further relates to a process for the production of 1-acyl-2-lyso-glycerophospholipid, preferably 2-lyso-PC by reacting glycerophospholipid, preferably glycerophosphoryl choline (GPC) with a desired carboxylic acid, preferably fatty acid, or their derivatives in the presence of a sn-1 specific phospholipase (PLA<SUB>1 </SUB>or PLA<SUB>1,2</SUB>) and a solvent, in a microaqueous medium.
Patent IL-148277-A0 (IL)
Title: Device for generating a pressure difference in a fluid and installation comprising it
IPC: C02F1/44
Filed: 1999-08-31
Abstract: The lifetime of a double-cone device (21) for creating a pressure difference in a streaming fluid can be greatly increased by moving the inlet gap (5) into the exit cone (4). This results in a short so-called diffuser (22) being obtained between the gap (5) and the orifice (19), where entry cone (3) and exit cone (4) are connected. The increased lifetime permits the double-cone device to cope with much higher flow rates. Thus higher system pressures are created which enhance the use of the double-cone for such applications as the desalination of sea water by reverse osmosis.The important application of the seperation of oil from water using a separating device such as a cyclone (57) working under elevated pressure is now feasible.The increased power of the double-cone permits one to profit more fully from the new concept of reduction of the concentration of the feed supplied to the double-cone device (21).
Patent IL-149954-A0 (IL)
Title: Method and system for telephone control
IPC: G06F13/00
Filed: 2000-11-27
Abstract: A print medium configured to be printed on by a pagewidth printhead in a print direction. The print medium includes: a laminar substrate defining first and second opposite faces; a data track containing first information encoded in accordance with a linear encoding scheme, the data track extending in a linear read direction across a portion of the first face of the print medium, the read direction being oriented at between 45 and 135 degrees with respect to the print direction; and a plurality of contiguous tags tiled across the laminar substrate. Each of the tags identifies second information and a two-dimensional coordinate position on the laminar substrate. Each of the tags is encoded in accordance with a second encoding scheme distinct from the linear encoding scheme. The information is indicative of the second information.
Patent IL-153121-A0 (IL)
Title: Polymer composition
IPC: H01M50/414
Filed: 2001-06-01
Abstract: The invention includes compositions comprising at least first and second polymers and optionally a third polymer wherein acid subunits, basic subunits and elastomeric subunits are contained in the polymers. In one aspect, the composition comprises a ternary polymer blend comprising an acidic polymer comprising acidic subunits, a basic polymer comprising basic subunits and an elastomeric polymer comprising elastomeric subunits. In an alternate aspect, the composition comprises a binary polymer blend which comprises acidic or basic subunits in one polymer and a copolymer comprising the other of the acidic or basic subunit and an elastomeric subunit. Such polymer compositions may be formed into a membrane having electrochemical properties which permit the use of such a membrane in an electrochemical device.
Patent IL-155689-A0 (IL)
Title: A method for decellularizing foreign material to produce bioprostheses
IPC: A61L2/02
Filed: 2001-12-05
Abstract: The invention relates to a method for decellularising allogenic and xenogenic foreign material for the subsequent production of bioprostheses, coated with endogenous body cells, whereby the foreign material is firstly treated in a solution of bile acid and then alcohol, each with an intermediate or subsequent rinsing step, in combination with a mechanical action on the tissue and the cells by the force generated from a flowing treatment medium, at least in the final rinsing step. After said treatment the tissue is completely rid of foreign cell material and viruses and represents an excellent starting material for the coating with cells of the bioprosthesis recipient.
Patent IL-157773-A0 (IL)
Title: 2-amino-propanol derivatives
IPC: A61P37/06
Filed: 2002-03-26
Abstract: Compounds of formula I wherein m, R, R<SUB>1 </SUB>and R<SUB>3 </SUB>to R<SUB>6 </SUB>are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive properties.
Patent IL-158977-A0 (IL)
Title: Runner rail clamping for fixing runner rails for sliding door systems
IPC: F16B5/12
Filed: 2002-08-16
Abstract: A single-piece track clamping holder for mounting a track of a sliding door system on a substrate includes a track receiver formed as a single piece and having a track receiving opening profiled to extend around more than half the circumference of a track, the track receiver having a wall bounding the receiving opening, and at least one clamping opening in the side of the wall facing the substrate. A clamping device received in each clamping opening can be acted on so that the holder is non-positively clamped to both the track and the substrate.
Patent IL-158988-A0 (IL)
Title: Method for consolidating a material web made from wood pulp
IPC: D04H1/732
Filed: 2002-05-24
Abstract: Production of a non-woven tissue from wood pulp on a wet strip is known. The above has a cardboardy, paper-like feel to it. In order to achieve a web with sufficient resilience, the desired wood pulp fibres used to advantage in the hygiene industry for absorbing liquids are thus always mixed with chemical fibres as support fibres. According to the invention, a consolidated tissue with a soft feel and high fluid absorption is obtained by means of needling a non-woven pure wood pulp tissue with water.
Patent IL-162478-A0 (IL)
Title: Phase shifted surface emitting dfb laser structures with gain or absorptive gratings
IPC: H01S5/187
Filed: 2002-12-11
Abstract: A surface emitting semiconductor laser is shown having a semiconductor lasing structure having an active layer, opposed cladding layers contiguous to said active layer, a substrate, and electrodes by which current can be injected into the semiconductor lasing structure. Also included is a distributed diffraction grating having periodically alternating elements, each of the elements being characterized as being either a high gain element or a low gain element. Each of the elements has a length, the length of the high gain element and the length of the low gain element together defining a grating period, where the grating period is in the range required to produce an optical signal in the optical telecommunications signal band. A phase shifting structure is provided in the center of the grating to cause a peak intensity to occur over the center of the cavity by altering a mode profile of the output signal, while spatial hole burning arising from said altered mode profile is ameliorated.
Patent RO-132503-A0 (RO)
Title: Method and device for controlling inaccessible areas
Inventor: IORDACHE DANIELA MONICA
IPC: G01B5/26
Filed: 2017-11-02
Abstract: The invention relates to a device for orienting and fastening blanks, meant to be used in the operations of controlling inaccessible areas, but also in machining and assembling operations. The claimed device comprises a base plate (1) with T-shaped channels on which some intermediary bodies (3) are positioned by means of some guiding wedges (2) fixed by some studs (4) and secured by some nuts (5), said bodies having at the upper part, on a T-shaped vertical channel, some supporting dish-ended pins (38) as a plane flat pre-orientation base and some main supports (15...17) with oscillating plane head defining the plane flat base for main orientation, attached on a support (14) and on an upper semi-hinge (13), blocked in the working position by a nut (12) on a stud (4), which are swung for allowing the access of some measuring instruments through a longitudinal ovalized through-channel, in relation to a bolt (11) articulated on a fixed semi-hinge (10) positioned and fastened by some simple wedges (7), a fastening wedge (8), and clamped with a screw (9) with a spherical collar on the T-shaped channels of the intermediary bodies (3), a main support as a fixed short prism (45), placed on an intermediary body (48), positioned and fastened, by some tangential guiding wedges (44) and a flange (47), onto the base plate (1), and a fixed plane supporting pin (50) placed on a support (49) which is attached onto a body (19) of a support with self-positioning and subsequent blocking of a single-block intermediary body (20) fastened on the base plate (1).
Patent AP-2002002406-A0 (AP)
Title: Prodrug of an ice inhibitor.
Inventor: WANNAMAKER MARION WOODS
IPC: C07D477/02
Filed: 2001-05-18
Abstract: This invention described an ice inhibitor prodrug (i)having good bioavaialability. Compound of formula (i)is useful for treating IL-1 mediated diseases such as rheumatoid arthritis, inflammatory bowel disease, crohn's disease, ulcerative colitis, inflammatory peritonitis, septic shock, pancreatitis, traumatic brain injury, organ trnasplant rejection, osteoarthritis, asthama, psoriasis, alzheimer's disese, mycardial infarction, congestive heart failure, huntington's disease, atherosclerosis, atopic dermatitis, leukemias and related disorders, myelodysplastic syndrome, uveitis or multiple myeloma.
Patent AP-2002002590-A0 (AP)
Title: Pyrimidinyl carboxamides useful as inhibitors of PDE4 isozymes.
Inventor: CHAMBERS ROBERT JAMES
IPC: C07D409/12
Filed: 2001-01-30
Abstract: Compounds of formula (1.0.0) are discribed, as well as the usefulness of a pharmaceutical composition for treating inflammatory, respiratory and allergic diseases and conditions, especially asthma; chronic obstructive pulmonary disease (COPD) including chronic bronchitis, emphysema, and brochiectasis; chronic rhinitis, and chronic sinusitis.
Patent MC-1321-A1 (MC)
Inventor: LUE HING C
IPC: B01D3/00
Filed: 1979-11-05
Abstract: An in-line distillation system for separating volatile components entrained in a liquid includes a distillation device for separating the volatile components from the liquid. A distribution device is connected in fluid communication with the outlet of the distillation and has a first conduit portion for flowing the separated volatile component from the outlet of the distillation device, and a second conduit portion for flowing the liquid from the outlet of the distillation device. A trap device resists the flow of the separated volatile component from entering the second conduit and thus forces the flow of volatile component into the first conduit. The trap device includes a reservoir container device for receiving liquid from the second container. An outlet at the upper portion of the container device spaced by a substantial distance above the exit end of said second conduit permits the flow of liquid therefrom.
Patent MA-38461-A1 (MA)
Title: Inhibiteurs de la voie de la kynurénine
Inventor: BANERJEE MONALI
IPC: C07D307/82
Filed: 2014-03-12
Abstract: La présente invention concerne de nouveaux inhibiteurs de l'indoleamine 2,3-dioxygénase-1 et/ou de l'indoleamine 2,3-dioxygénase-2 et/ou du tryptophane 2,3-dioxygénase, des métabolites de ceux-ci, et des sels ou des promédicaments pharmaceutiquement acceptables de ces derniers. L'invention concerne également des méthodes de préparation de ces composés. Une quantité thérapeutiquement efficace d'un ou de plusieurs des composés de formule (i) est utile dans le traitement de maladies résultant d'un dérèglement de la voie de la kynurénine. Les composés de formule (i) agissent en inhibant l'activité enzymatique ou l'expression de l'indoleamine 2,3-dioxygénase-1 et/ou de l'indoleamine 2,3-dioxygénase-2 et/ou du tryptophane 2,3-dioxygénase.
Patent MA-42005-A1 (MA)
Title: Procédé et appareil de refroidissement d'un gaz contenant du so
Inventor: DAUM KARL-HEINZ
IPC: F28D21/00
Filed: 2016-06-30
Abstract: L'invention susmentionnée concerne un procédé de refroidissement d'un mélange gazeux de so
Patent UY-23978-A1 (UY)
Title: Elemento hinchable para señalizacion
Inventor: FORCINITI DILIO ANTONIO
IPC: E01F9/00
Filed: 1995-06-16
Abstract: La presente invención se compone de un cuerpo hinchable (1) provisto de fondo convexo (2) en el cual se incorpora un compartimiento (3) dispuesto en la faz inferior interna (4) y que se rellena con un aglomerado (5) compuesto por arena u otro material adecuado; el cuerpo hinchable (1) incorporando una válvula destinada a regular la entrada y la salida del aire empleado para hinchar dicho cuerpo hinchable (1), el cual se obtiene en material laminado, siendo sus funciones ejecutadas en acabamiento a través de soldadura electrónica a lo largo de líneas (8a) y (8b); externamente el cuerpo hinchable (1) incorpora un patrón de franjas (9) definidas de colores contrastantes y en patrones de arreglo que pueden ser diagonal, vertical u horizontal, dichas franjas (9) contando con aplicación de material reflectivo (10). (ver Fig. 1 y 2)
Patent UY-25791-A1 (UY)
Title: Combinaciones para la diabetes
Inventor: WHITCOMB RANDALL W
IPC: A61K31/155
Filed: 1999-11-05
Abstract: De acuerdo con esta invención, se usa una glitazona en combinación con una biguanida, o en combinación con una sulfonilurea y una biguanida, para tratar la diabetes y para mejorar el control glucémico en pacientes que necesitan el tratamiento. Los compuestos pueden emplearse individualmente, o combinarse en una formulación única, p. ej. una tableta, cápsula, jarabe, solución, así como formulaciones de liberación controlada. VER REIV.
Patent UY-26952-A1 (UY)
Title: Nuevas composiciones farmacéuticas que contienen epinastina y pseudoefedrina
Inventor: ABELAIRA SARA
Filed: 2001-10-04
Abstract: El presente invento se refiere a nuevas composiciones farmacéuticas orales que comprenden como compuestos farmacéuticamente activos una combinación de una cantidad eficaz como antihistamínica de epinastina o una sal farmacéuticamente aceptable de la misma y de una cantidad eficaz como descongestionante de pseudoefedrina o una sal farmacéuticamente aceptable de la misma, y que comprenden además apropiados vehículos o excipientes farmacéuticamente aceptables. El invento se refiere además a métodos para la preparación de estas composiciones y métodos de usarlos en el tratamiento de enfermedades y/o trastornos alérgicos.
Patent UY-27891-A1 (UY)
Title: Nuevos derivados de glicosido de tiofeno, procedimientos para la preparación de los mismos, medicamentos que contienen estos compuestos, y el uso de los mismos.
Inventor: GLOMBIK DR HEINER
IPC: A61P3/04
Filed: 2003-07-11
Abstract: Nuevos derivados de glucósido de tiofeno, procedimientos para la preparación de los mismos, medicamentos que contienen estos compuestos, y el uso de los mismos. La invención se refiere a nuevos derivados de glucósido de tiofeno de fórmula I en los cuales los radicales tienen los significados que se han indicado, y a las sales fisiológicamente toleradas de los mismos y a procedimientos para su preparación. Los compuestos son adecuados, por ejemplo, como agentes antidiabéticos.
Patent UY-28945-A1 (UY)
Title: Derivados de pirrolopiridina
Inventor: EATHERTON ANDREW JOHN
IPC: C07D401/02
Filed: 2005-06-07
Abstract: La presente invención se refiere a nuevos derivados de pirrolopiridina, a composiciones farmacéuticas que contienen estos compuestos y a su uso en el tratamiento de enfermedades, particularmente dolor, que se produce directa o indirectamente por un aumento o reducción de la actividad del receptor de cannabinoides.
Patent ES-153595-A1 (ES)
Title: BASTIDOR - SOPORTE PARA GENERADORES DE ACETILENO U OTROS, MONTADOS SOBRE VEHiCULOS AUTOMoVILES
Filed: 1941-07-02
Abstract: Bastidor-soporte para generadores de acetileno u otros gasesmontados sobre vehículos automóvilescaracterizado porque está suspendido del eje trasero mediante una unión elásticasencilla o múltipley porque está unido con el chasis mediante dos sistemas pendulares susceptibles de permitirle una ligera oscilación en un plano paralelo al plano mediano del vehículode modo de responder a los movimientos de la suspensión elástica.
Patent ES-178216-A1 (ES)
Title: Un procedimiento para la obtencion de amidas y cuerpos afines a partir de esteres de acidos carboxilicos aromaticos
Filed: 1947-05-20
Abstract: Procedimiento para la obtención de amidas y cuerpos afines a partir de esteres de ácidos carboxílicos aromáticos de la fórmula general ** ( Ver fórmula )** en la cual X puede ser un radical alquílico cualquiera consistiendo dicho procedimiento en provocar la reacción del producto clorado en el grupo sulfónico de la fórmula general antes citada con amoniaco acuoso a 02 centígrados formándose en esta operación la amida hasta el momento en que por análisis sucesivos del líquido acuoso filtrado se encuentre una cantidad de cloruro amonico tal. que corresponda a la de la amida formada con lo cual. se podrá determinar el. momento en que queda terminada la reacción puesto que por cada molécula de amida se habrá formado una molécula de cloruro amonico.
Patent ES-179260-A1 (ES)
Title: MEJORAS INTRODUCIDAS EN LA FABRICACIoN DE CURSORES PARA CONTINUAS DE HILAR O TORCER
IPC: D01H7/60
Filed: 1947-08-07
Abstract: Mejoras introducidas en la fabricación de cursores para continuas de hilar o torcer caracterizadas porque los mismos tienen una superficie de desgaste que comprende polistireno.
Patent ES-179908-A1 (ES)
Title: Mejoras en cables eléctricos coaxiales
IPC: H03H5/00
Filed: 1947-09-27
Abstract: Mejoras en cables eléctricos coaxiales caracterizados por estar cargados inductivamente parte de los mismos con material magnético de tal modo que se aumenta la impedancia longitudinal sin aumentar la transversal.