baber/WOPTO huggingface dataset:
Patent CN-100476266-C (CN)
Inventor: DAISUKE INOUE
IPC: F16D48/02
Filed: 2006-10-23
Granted: 2009-04-08
Abstract: 本发明公开了一种摩擦啮合元件的控制设备及控制方法。如果锁止离合器松开(在S100为“是”)且变矩器的输入轴的转数或速度NE减去变矩器的输出轴的转数或速度NT小于阈值ΔN(1)(在S200为“是”)，则ECT_ECU执行包含禁止锁止离合器啮合的步骤(S500)的程序。
Patent CN-100515790-C (CN)
Inventor: XUEZHOU WANG
IPC: B41K3/00
Filed: 2006-12-19
Granted: 2009-07-22
Abstract: 本发明公开了一种计米印字机，包括机头，设置在机头上的印字轮，设置在印字轮上的计米器，设置在印字轮圆周面上的字模，和设置在机头上用于传动印字轮的传动装置，所述的机头上设置有移印轮和上墨轮，移印轮设置在上墨轮和印字轮之间，移印轮圆周面上设置有一凸起的胶皮块，所述的移印轮通过其上凸起的胶皮块和字模相接触，在上墨轮的下面设置有油墨盒，上墨轮的一侧设置有刮刀，其优点是：该计米印字机取消了色带和加热装置，解决了由于色带和承印物不匹配不能打印的问题，降低了成本，适用范围更宽，且工作性能可靠。
Patent CN-100506040-C (CN)
Inventor: YUNSHENG ZHANG
IPC: A01N61/00
Filed: 2006-12-29
Granted: 2009-07-01
Abstract: 一种抗旱耐盐碱多功能棉花种衣剂，包括活性组分杀虫剂、杀菌剂、植物生长调节剂，非活性组分成膜剂及助剂，其特征在于所述组分的重量比构成为：拌种灵3.4%-4.0%，福美双3.3%-4.0%，乙酰甲胺磷11.0%-12.0%，黄腐酸0.1%-0.8%，羧甲基纤维素钠0.2%-0.3%，黄原胶0.05%-0.15%，消泡剂0.3%-4.0%，乙二醇4.5%-5.5%，警戒色0.5%-2.0%，水余量。本棉花种衣剂具有悬浮率高、成膜性好、包衣均匀、脱落率低、低毒、使用方便、成本低等特点。并具有杀虫灭菌助长、抗盐碱、抗旱保水等功能。与不包衣比较，棉种发芽率可提高12%左右，提高棉花产量12%以上。
Patent CN-100584697-C (CN)
Inventor: LIONEL DIOCHON
IPC: B64C27/18
Filed: 2006-05-22
Granted: 2010-01-27
Abstract: 本发明涉及一种用于航空器的涡轮喷气发动机挂架，该挂架具有包括纵向中央沉箱(22)的刚性结构(10)。根据本发明，刚性结构(10)还包括两个与所述中央沉箱(22)的前部相连接的侧部沉箱(24a，24b)，挂架还包括设计为吸收沿挂架纵向方向(X)上施加的作用力的第一(6a)和第二前发动机附件(6b)，所述第一和第二前发动机附件分别设置在两个侧部沉箱上。
Patent CN-100537705-C (CN)
Title: 一种聚合物分散液晶薄膜的制备方法
Inventor: GUOLIANG ZHANG
IPC: C09K19/00
Filed: 2007-08-15
Granted: 2009-09-09
Abstract: 本发明属于液晶材料应用及相关领域，是一种聚合物分散液晶(PDLC)薄膜的制备方法，将1，2-二正烯丁基苯乙炔化合物，刚性双官能团丙烯酸酯类可聚合单体，甲基丙烯酸甲酯按质量比8∶2∶3～8∶3∶2混合均匀，并将该混合物作为聚合物分散液晶薄膜的聚合单体与列型液晶按质量比2∶8～8∶2混合均匀，在室温下形成各向同性液体。将各向同性液体、光引发剂和纳米微珠均匀混合后夹在两片镀有ITO的透明导电膜中间，用辊压匀，形成膜层，在各向同性液体的清亮点以上0.5～3℃内用365nm的紫外光进行照射得到PDLC薄膜。本发明可改善PDLC材料的驱动电压，增强聚合物网络强度、从而提高PDLC薄膜电光性能的稳定性。
Patent CN-100582035-C (CN)
Title: 一种煅烧石英制备方石英的方法
Inventor: CHUNJIE YAN
IPC: C03B20/00
Filed: 2007-03-05
Granted: 2010-01-20
Abstract: 本发明涉及一种煅烧石英制备方石英的方法。一种煅烧石英制备方石英的方法，其特征在于它包括如下步骤：1)、将石英粉料与相变催化剂混合均匀，得配合料；所述的相变催化剂为Y 2 O 3 、Na 2 CO 3 和BaF 2 所组成的复合催化剂，Y 2 O 3 的加入量为石英粉料重量的1‰-5‰，Na 2 CO 3 的加入量为石英粉料重量的5‰-10‰，BaF 2 的加入量为石英粉料重量的1‰-5‰；2)、将配合料以每分钟2℃-10℃的速度升温至1300℃，在1300℃保温6小时，得方石英相大于94%的产品。该方法能耗低、生产成本低，且转化率高。
Patent CN-100451947-C (CN)
Title: 一种虚拟液晶显示器
Inventor: MANPING ZHU
IPC: G09G5/02
Filed: 2007-05-09
Granted: 2009-01-14
Abstract: 本发明是一种虚拟液晶显示器。使用本发明时，仅需要一块电路板和运行在PC上的软件，即可在PC上虚拟出采用数字扫描接口的各种分辨率的液晶显示器。本发明可在电子实验或电子产品开发时代替较昂贵且不便的液晶显示器，从而降低成本，增加了灵活性。
Patent CN-100595897-C (CN)
Inventor: MINGDA SHAO
IPC: H01L21/58
Filed: 2008-08-20
Granted: 2010-03-24
Abstract: 本申请提供晶圆级封装对象及其形成的方法。在形成晶圆级封装对象的方法中，将小尺寸的单个芯片、含有两个以上芯片的晶圆部件或经过一道以上封装步骤形成的芯片封装半成品重组在一个衬底上；或者用整个晶圆切割而形成的具有至少两个芯片的晶圆部件与粘合用基底进行粘合，用以形成晶圆级封装对象，使得较大尺寸的晶圆可以在较小尺寸的晶圆级封装设备上进行晶圆级封装，延长了晶圆级封装设备的使用寿命，降低了成本，并且能使企业在不进行大量更新设备的情况下，能跟上市场的发展和晶圆不断增大的趋势。
Patent MX-3408-E (MX)
Title: Procedimiento para preparar n,n' '-tio y ditio bis (fenil substituidos) n-metil-formamidinas
Inventor: RIZZO VICTOR LAWRENCE
IPC: C07C67/00
Filed: 1976-04-09
Abstract: La presente invención se refiere a un procedimiento para preparar N,N ' '-tio y ditio bis (fenil substituidos) N-metil-formamidinas, de la fórmula. (VER FIGURA) en donde n es 1 ó 2, R1 y R2 son iguales ó diferentes y se seleccionan del grupo que consiste de un alquilo inferior de 1 a 4 átomos de carbono o, inclusive R3 y R4 son lo mismo y están seleccionados del grupo que consiste de hidrógeno, halógeno, y alquilo inferior de 1 a 4 átomos de carbono, inclusive, que comprende hacer reaccionar 2 moles de un compuesto de la fórmula II (VER FIGURA) con un mol de dicloruro de azufre (S-Cl2) cuando n es 1 ó un mol de monocloruro de azufre (Cl-S-S-Cl) cuando n es 2, en la presencia de un separador de ácido en un disolvente inerte a una temperatura de -30°C a la temperatura de reflujo.
Patent PT-1197207-E (PT)
Title: Stable compositions for parenteral administration
Inventor: STEBER WILLIAM DAVID
IPC: A61P33/10
Filed: 2001-09-28
Abstract: This invention relates to certain stable microsphere compositions containing a fat, a wax or a mixture thereof; and an active ingredient selected from LL-F28249 alpha - lambda , compounds, 23-oxo or 23-imino derivatives of LL-F28249 alpha - lambda compounds, milbemycin compounds and avermectin compounds. The invention also relates to a method for introducing and maintaining levels of the active compound in the blood of warm-blooded animals for extended periods of time and for the prevention or treatment of infections and infestations caused by helminths, nematodes, acarids and endo- and ectoparasitic arthropods in warm-blooded animals by the parenteral administration of compositions of the invention.
Patent PT-1276563-E (PT)
Inventor: KLINKSIEK BERND
IPC: C08G65/26
Filed: 2001-04-17
Abstract: The invention provides an improved process for the preparation of double metal cyanide (DMC) catalysts for the preparation of polyether polyols by polyaddition of alkylene oxides on to starter compounds containing active hydrogen atoms, in which aqueous solutions of a metal salt and a metal cyanide salt are first reacted in the presence of an organic complexing ligand and optionally one or more further complex-forming components to form a DMC catalyst dispersion, this dispersion is then filtered, the filter cake is subsequently washed with one or more aqueous or non-aqueous solutions of the organic complexing ligand and optionally one or more further complex-forming components by a filter cake washing and the washed filter cake is finally dried, after an optional pressing out or mechanical removal of moisture.
Patent PT-1294467-E (PT)
Title: A process for reducing pollutants from the exhaust of a diesel engine
Inventor: BROWN KEVIN F
IPC: C09K23/52
Filed: 2001-06-15
Abstract: This invention relates to a process for reducing the level of pollutants in the exhaust of a diesel engine, comprising: operating said diesel engine using as the fuel a water-diesel fuel emulsion; and contacting the exhaust gas from said diesel engine with an after-treatment such as a filter.
Patent PT-1347736-E (PT)
Title: Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically sulfonated unsaturated monomer with sulphonic group and comprising a hydrophobic part
Inventor: LAGRANGE ALAIN
IPC: A61Q5/00
Filed: 2001-12-19
Abstract: The invention concerns a cosmetic composition for treating keratinous materials comprising in a carrier suitable for keratinous materials: (a) at least an amphiphilic polymer comprising at least an ethylenically unsaturated monomer with sulphonic group, in free form or partly or completely neutralized and further at least a hydrophobic part; (b) at least an oxidizing agent.
Patent PT-1448907-E (PT)
Title: Coupling device, preferably between an actuator and a valve
Inventor: NILSSON CURT
IPC: F16D1/08
Filed: 2002-05-24
Abstract: The present invention relates to a valve (1) between a shaft (2) and a force-transmitting organ (3), comprising a non-play-free form-locking coupling (21, 34, 4) that is arranged between said force-transmitting organ (3) and said shaft (2), which coupling (21, 34, 4) is dimensioned such that a certain maximum first torque (M1) can be transmitted via said coupling, a second coupling, the form of an essentially non-form-locking coupling (6, 7) dimensioned for a certain maximum second torque (M2), being arranged between said shaft (2) and said force-transmitting organ (3), which coupling complements and relieves said form-locking coupling (21, 34, 4), said essentially non-form-locking coupling (6, 7) being play-free.
Patent PT-1370547-E (PT)
Inventor: VACHER BERNARD
IPC: A61P9/10
Filed: 2002-03-20
Abstract: 3-(arylthiopropylamino)-1,5-aryloxathiepine derivatives (I) are new.  3-(arylthiopropylamino)-1,5-aryloxathiepine derivatives of formula (I) and their (hydrated) addition salts with (in)organic acids, tautomers, enantiomers and stereoisomers are new. R1 and R2  = H, fluoro, chloro, hydroxy, 1-3C alkyl, cyclopropyl, cyclopropoxy; or R1 +R2 = 5-membered non-aromatic ring, optionally including an oxygen atom;  R3  = 1-3C alkyl, hydroxy or MeO;  R4  = H or Me; and R5 and R6  = hydrogen, 1-3C alkyl, alkoxy or alkylthio, or alkylamino. Provided that when R4 is Me, the R5 is not alkyl, or OR4 and R5 complete a 5- or 6-membered ring containing at least one oxygen. Independent claims are also included for: (1) Methods for preparing (I);  (2) Intermediate amines of formula (VI);  (3) Method for preparing (I);  (4) Aldehydes of formulae (II) and (V); and  (5) Methods for preparing (II) and (V). R3 = 1-3C alkyl or MeO; and R4 = Me in (II) or methoxymethyl in (V).
Patent PT-1338199-E (PT)
Title: Herbicidal compositions
Inventor: FENDERSON JOHN MELVIN
IPC: A01N37/18
Filed: 1994-02-15
Abstract: A method of controlling undesired plant growth which comprises co-application to the locus of said undesired plants growth dimethenamid and pendimethalin in a herbicidally effective aggregate amount.
Patent PT-1512695-E (PT)
Title: Hypoallergenic polypeptides based on fish parvalbumin
Inventor: VALENTA RUDOLF
IPC: A61K38/00
Filed: 2003-09-04
Abstract: The present invention relates to non-naturally occurring polypeptides derived from fish allergens such as parvalbumin Cyp c 1.01 from carp. The polypeptides display reduced allergenic activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.
Patent PT-1578214-E (PT)
Title: Food composition comprising a satiety enhancing amount of triacylglycerol
Inventor: HERSLOEF BENGT
IPC: A23L29/10
Filed: 2003-12-21
Abstract: In a method of controlling satiety a food product comprising a satiety controlling amount of a food additive, which consists of a triacylglycerol or a mixture of triacylglycerols, and an emulsifier is provided to a person. Acyl is tetradecanoyl to eicosanoyl, optionally mono- or di-unsaturated, optionally alpha-monosubstituted with saturated C<SUB>1</SUB>-C<SUB>4 </SUB>alkyl. More than 15 mole-% of total acyl is comprised by alpha-substituted acyl. The person is directed to consume the food product from 1 h to 8 h prior to a meal. Thereby the amount of food consumed in the meal is reduced in comparison with the amount of food consumed in a corresponding meal following, by a corresponding time difference, the consumption of a food product of equal energy content but lacking the additive. Also disclosed are corresponding additives and compositions comprising them, and their use.
Patent PT-1458073-E (PT)
Title: Kit for distribution cabinet
Inventor: IRMER GUENTER
IPC: H02B1/01
Filed: 2004-03-12
Abstract: The profiled frame members (51,52) may be held together by square corner pieces (61,62) at their ends, on the outsides of the corners. There are triangular corner pieces (71,72) on the insides of the 90 degree corners. The profiled frame members have a modified square cross-section, with reentrant grooves in the center of each side and at each corner. The grooves may accommodate hangers or hooks for holding equipment, filling pieces or electrical cables (69) and corner pieces. They may also accommodate support members (40) and electrical sockets (77).
Patent PT-1616592-E (PT)
Title: Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge for use with this inhaler
Inventor: JOACHIM GOEDE DR
IPC: A61M15/00
Filed: 2005-07-12
Abstract: In order to improve the security and reliability of administration of powdered pharmaceuticals through dry powder inhalers, the invention proposes an inhaler (1) for powdered medicaments, comprising an activating device (4) for manual engagement by the patient for repeatedly metering a dose of medicament to be administered to the patient, and further comprising an advancing mechanism (25) for advancing a counter or indexing means (8) each time the activating device (4) has been engaged by the patient so that a dose of medicament has been released for administration to the patient, wherein the counter or indexing means (8) comprises an index (9), the index (9) being detectable by a detection means (10) of the inhaler, and the detection means (10) being coupled to a locking mechanism (12), the locking mechanism (12) blocking the activating device (4) and/or any transportation mechanism (5) of the inhaler (1) delayed by a predetermined number of metering cycles since detection of the index (9), and a cartridge (3).
Patent PT-1640217-E (PT)
Title: Rear bumper support for motor vehicle
Inventor: LAMOTTE PHILIPPE
IPC: B60R19/24
Filed: 2005-07-25
Abstract: The support has two fixation units (2, 3) for fixing a bumper on a rear part of a chassis (1) of a motor vehicle. A cross-member (4) with two opposite ends is arranged on the fixation units to form a supporting structure between the units. The cross-member is made of a thermosetting material, and has an upper side which constitutes the supporting structure for an upper part of the bumper.
Patent PT-1787793-E (PT)
Title: Apparatus for shaping trays from blank sheets
Inventor: BINI LUCA
IPC: B31B50/46
Filed: 2006-11-13
Abstract: An apparatus for making edged trays (9'') from blank sheets (9,9') , of the type comprising a stationary store (2) for a plurality of these stacked blank sheets (4), a first moving member (6) for at least one (9) of these sheets, one or more tray-forming walls (5a,5b,5c) being arranged substantially at the store outlet section, and being movable between an at least partially closed position and an opened position of said store outlet section, as well as at least one storage station (12) for the tray. Said first moving member is movable according to a rectilinear reciprocating motion between a take-up position of at least one blank sheet, within the store, and a position of releasing the tray at the storage station, and further this first moving member, in the rectilinear reciprocating motion thereof, also acts as a pusher for forcedly inserting the sheet into the forming walls.
Patent PT-1884730-E (PT)
Title: A tunnel kiln for ceramic products
Inventor: PIFFERI GIUSEPPE
IPC: F27B9/36
Filed: 2007-05-18
Abstract: A tunnel kiln (1) for ceramic products comprising two opposite lateral walls (2), a horizontal roller conveyor (5) destined to support and advance a layer of tiles (100) internally of the kiln (1), a first series of burners (51) and a second series of burners (52) arranged aligned along the two lateral walls and facing towards the opposite wall, each burner (51) of the first series (51) being provided exclusively with an axial flame such as to heat a central zone of the tunnel while each burner (52) of the second series is provided with at least a radial-flame nozzle such as to beat a zone which is proximal to the lateral wall of the tunnel, each burner (51, 52) of the first and the second series being connected to a common conduit (60) of combustible gas and respectively to a first (510) and a second (520) conduit of a comburent, comprising: means (523) for detecting a dimensional out-of-size with respect to a design project specification for the products exiting the kiln (1); a control unit (522) for receiving data coming from the means (523) for detecting; means for regulating (521) a flow rate of the comburent to the burners (52) of the second series on the second conduit (520) of the comburent, the means for regulating (521) of the comburent flow rate being controlled by the control unit (522) which is programmed to command the means for regulating (521) according to the data received from the means for detecting (523).
Patent PT-2086354-E (PT)
Title: Method for producing a low sodium salt composition
Inventor: RAO CHIGURUPATI SAMBASIVA
IPC: A23L29/294
Filed: 2007-10-05
Abstract: The present invention relates to a low sodium salt composition and the method used to make it. More particularly, the invention relates to a two step method of making a salt composition. The first step includes contacting a chloride salt with a modifier to form a chloride salt product, mixing the product with a carrier to form a modified chloride salt solution, and drying the modified chloride salt solution. The second step includes contacting the dried modified chloride salt with sodium chloride, and grinding the mixture to form a salt composition. The composition includes a combination of sodium chloride and carrier modified chloride salt.
Patent PT-2217078-E (PT)
Title: Device for receiving and fixing fish within a device for processing fish
Inventor: OSTROWSKY PETER
IPC: A22C25/14
Filed: 2008-09-23
Abstract: The device (10) has a torso clamp (11), and a pectoral fin receiver (14) formed of catches (12, 13). The clamp is brought from a receiving position to a clamping position and vice versa, and an additional unit (19) fixes a fish torso. The unit has clamping straps (20, 21) arranged on opposite sides of a fish. The clamp is formed of a rear support (15) and side webs (16, 17) that stand in effective connection with each other. The straps are connected with the webs such that the straps are positively connected by the webs. The straps are formed of clamping elements made of sheet metal.
Patent PT-2240654-E (PT)
Title: Submerged-surface cleaning apparatus with angled pumping impeller
Inventor: PICHON PHILIPPE
IPC: E04H4/16
Filed: 2008-12-18
Abstract: Detailed is a device for cleaning an immersed surface including a body and members for driving the body over the immersed surface, a filtration chamber which is provided in the body and which has: a liquid inlet located at the base of the body; a liquid outlet arranged opposite the base of the body; a hydraulic circuit for flow of liquid between this liquid inlet and this liquid outlet through a filtering device; a liquid pumping device including a pumping motor which has a rotating drive shaft which is coupled to a pumping propeller which is interposed in the hydraulic circuit, wherein the liquid outlet is longitudinally offset from the liquid inlet and the pumping propeller has an inclined rotation axis which forms, with the longitudinal direction, an angle which is not equal to zero and which is different from 90°.
Patent PT-2133349-E (PT)
Title: Kinase inhibitors
Inventor: STAFFORD JEFFREY A
IPC: A61P35/00
Filed: 2006-10-10
Abstract: The invention provides a compound of formula:   
or a pharmaceutically acceptable salt, biohydrolysable ester, biohydrolysable amide, biohydrolysable carbamate, solvate or hydrate thereof, wherein R 1 , R 2 , R 4 , R 5 , R 6 , R 7 , Y 3  and R 14  have the meanings given in the specification. The compounds are kinase inhibitors and are useful in treating a number of disorders, including cancer, inflammation, dementia related diseases and arthritis.
Patent PT-2385053-E (PT)
Title: Intermediates for the preparation of fused bicyclic mtor inhibitors
Inventor: ARNOLD LEE D
IPC: C07D253/07
Filed: 2006-11-15
Abstract: Compounds represented by Formula (I)   
or a pharmaceutically acceptable salt thereof, are inhibitors of mTOR and useful in the treatment of cancer.
Patent PT-2343829-E (PT)
Title: Method and apparatus for variable accuracy inter-picture timing specification for digital video encoding
Inventor: SINGER DAVID W
IPC: H04N19/94
Filed: 2003-07-11
Abstract: A method and apparatus for variable accuracy inter-picture timing specification for digital video encoding is disclosed. Specifically the present invention discloses a system that allows the relative timing of nearby video pictures to be encoded in a very efficient manner. In one embodiment, the display time difference between a current video picture (105) and a nearby video picture is determined. The display time difference is then encoded (180) into a digital representation of the video picture. In a preferred embodiment, the nearby video picture is the most recently transmitted stored picture. For coding efficiency, the display time difference may be encoded using a variable length coding system or arithmetic coding. In an alternate embodiment, the display time difference is encoded as a power of two to reduce the number of bits transmitted.
Patent PT-682528-E (PT)
Inventor: GIZURARSON SVEINBJORN
IPC: A61K39/145
Filed: 1994-02-14
Abstract: PCT No. PCT/DK94/00062 Sec. 371 Date Oct. 6, 1995 Sec. 102(e) Date Oct. 6, 1995 PCT Filed Feb. 14, 1994 PCT Pub. No. WO94/17827 PCT Pub. Date Aug. 18, 1994A novel type of formulation for the topical administration of antigens and/or vaccines to mammals via mucosal membranes comprising one or more adjuvants/vehicles selected from (a) polyoxyethylene sorbitan monoesters, (b) polyoxyethylene castor oil, (c) caprylic/capric acid glycerides and (d) gangliosides in an amount of 0.01 to 15% (v/v) calculated on the total volume of the preparation. This formulation enhances the immunological response n a mammal following mucosal administration, e.g. nasal, oral, rectal or vaginal application.
Patent PT-702683-E (PT)
Inventor: MCMURRY THOMAS BRIAN
IPC: C07D473/18
Filed: 1994-06-08
Abstract: O &cir& _<6>-hetarylalkyl- or naphthylalkylguanine derivatives of formula (I) wherein Y is H, ribosyl, deoxyribosyl, or R"XCHR"', wherein X is O or S, R'' and R''' are alkyl, or substituted derivatives thereof; R' is H, or alkyl or hydroxyalkyl; R is (i) a cyclic group having at least one 5- or 6-membered heterocyclic ring, optionally with a carbocyclic or heterocyclic ring fused thereto, the or each heterocyclic ring having at least one hereto atom chosen from O, N or S, or a substituted derivative thereof; or (ii) naphthyl or a substituted derivative thereof; and pharmaceutically acceptable salts thereof, exhibit the ability to deplete O &cir& _<6>-alkylguanine-DNA alkyltransferase (ATase) activity. A process for preparation of the compounds is described. The compounds have utility in combination with alkylating agents in the chemotherapeutic treatment of tumour cells.
Patent PT-771198-E (PT)
Inventor: ANDERSON BENJAMIN ALAN
IPC: C07D491/056
Filed: 1995-08-30
Abstract: Compounds having general formula (I) wherein R is hydrogen or C 1  - C 10  alkyl; X is an aromatic moiety selected from phenyl, thienyl, furyl, pyridyl, imidazolyl, benzimidazolyl, benzothiazolyl and phthalazinyl which is unsubstituted or substituted with one or more moieties chosen from the group consisting of halogen, hydroxy, cyano, nitro, C 1  - C 6  alkyl, C 3  - C 6  cycloalkyl, C 1  - C 4  alkoxy, carboxy, C 1  - C 6  alkoxycarbonyl, acetyl, formyl, carboxymethyl, hydroxymethyl, amino, aminomethyl, methylenedioxy and trifluoromethyl; and "Aryl" represents p-nitrophenyl, p-aminophenyl or p-(protected amino) phenyl; or a pharmaceutically acceptable salt thereof, are useful as anticonvulsants.
Patent PT-788554-E (PT)
Inventor: GALLAGHER JOHN THOMAS
IPC: C12Q1/34
Filed: 1995-10-30
Abstract: A method of analyzing and sequencing saccharide material composed of saccharide chains. The saccharide chains are end referenced, e.g., by labeling or tagging at their reducing ends, and the saccharide material is subjected to a controlled partial depolymerisation using a selection scission reagent, for example, low pH nitrous acid, which cleaves internal glycosidic linkages in accordance with known linkage specificity so as to produce a mixed set of saccharide chain fragments having different lengths ranging throughout the full spectrum of possible lengths for the particular glycosidic linkage specificity of the selective scission reagent employed. Samples of the mixed set of saccharide chain fragments are then treated with selected exoenzymes including exoglycosidases that cleave only particular glycosidic linkages at the non-reducing end of saccharide chains. These exoenzymes are applied to the samples either singly or in combination in accordance with a predetermined strategy. The treated samples are then analyzed, to detect the chain fragments present which have a reducing end derived from the reducing end of the corresponding chain in the original saccharide material and the monosaccharide sequence in the saccharide starting material is then deduced.