baber/WOPTO huggingface dataset:
Patent CZ-292174-B6 (CZ)
Title: Process for preparing citalopram
Inventor: PETERSEN HANS
IPC: C07D307/87
Filed: 1999-11-19
Abstract: In the present invention there is disclosed a process for preparing citalopram, which preparation process is characterized by reacting the compound of the general formula IV, in which R represents a chlorine or bromine atom, with a cyanide source in the presence of a nickel-based catalyst and subsequently isolating a corresponding 5-cyano compound, i.e. citalopram of the general formula I in a free form or in the form of a pharmaceutically acceptable salt.
Patent CZ-299384-B6 (CZ)
Title: Extract from amaranth phytomass and process for producing thereof
Inventor: JELINEK MILOUE
IPC: A23L35/00
Filed: 2001-03-05
Abstract: In the present invention, there is disclosed extract from amaranth phytomass comprising dry matter, wherein each 2 to 3 grams thereof contain 0.6 to 0.9 gram of bioflavonoids that are represented particularly by rutin. In addition, the extract can contain dyes based on antocyans, whereby usually in each liter of the extract 0.3 to 0.5 mg of antocyan is comprised. There is also disclosed a process for preparing the above-described amaranth extract wherein the preparation process is characterized in that crushed and dried phytomass of amaranth plant is subjected to extraction in water and acid medium having pH value within 4.0 to 5.5. The phytomass is then mixed with water during extraction, solid and liquid phases are separated from each other wherein the obtained extract has dry matter of 2 to 3 percent by volume. Mixing the phytomass with water is carried out for a period of at least 30 minutes and the obtained extract can be thickened to 10 to 15 percent by volume of dry matter.
Patent CZ-299712-B6 (CZ)
Title: Use of dapoxetine on an as-needed basis for management of sexual dysfunction
Inventor: THOR KARL BRUCE
IPC: A61P15/08
Filed: 2000-08-22
Abstract: In the present invention, there is disclosed the use of dapoxetine, or a pharmaceutically acceptable salt thereof, on an as-needed basis, for the manufacture of a medicament for the prevention, treatment, or management of sexual dysfunction in a mammal, particularly premature ejaculation, by administering to a patient in need of therapy a therapeutically effective amount of the medicament on an as-needed basis shortly before sexual activity.
Patent CZ-305996-B6 (CZ)
Title: Apparatus for continuous production of spun-bond web
Inventor: GEUS HANS GEORG
IPC: D04H3/033
Filed: 2003-02-27
Abstract: In the present invention, there is disclosed an apparatus for the continuous production of a spun-bond web, comprising: a spinneret for producing a multiplicity of descending thermoplastic synthetic resin filaments; a device below said spinneret and receiving said multiplicity of descending thermoplastic synthetic resin filaments for aerodynamically stretching same; a continuously movable collecting foraminous belt (7) displaceable longitudinally in a web-producing direction below said device for receiving said filaments to produce a spun-bond web therefrom; and at least two mutually independently controllable suction zones beneath said belt for drawing air therethrough and in succession in said direction, including a primary suction zone (11) at which a greater part of the filaments are drawn onto said belt and at least one other suction zone. The apparatus is characterized in that three of said suction zones (10, 11, 12) are provided in succession beneath said belt in said direction including a first suction zone upstream of said primary suction zone (11) said primary suction zone (11) and a second suction zone (10, 12) downstream of said primary suction zone, said suction zones having suction speeds which are settable independently of one another. The apparatus further comprises a drawing unit (4) being formed with a drafting channel (5) in which the filaments are pulled downwardly to enter a tiering unit (6) with at lest one diffuser (13, 14).
Patent SK-287876-B6 (SK)
Title: Crystalline polymorph of epothilone analog, method for producing thereof, pharmaceutical composition comprising as active ingredient this polymorph and use of this crystalline polymorph for manufacture of medicament
Inventor: DIMARCO JOHN D
IPC: C07D491/04
Filed: 2001-08-01
Abstract: Described are crystalline polymorphic forms of an epothilone analog of the general formula (I), designated Form A and Form B, and the mixtures thereof, a process for producing thereof, a use of these crystalline polymorphs for the manufacture of a medicament and pharmaceutical dosage forms containing them.
Patent CZ-296021-B6 (CZ)
Title: Preheater for preheating fed charging stock and melting unit
Inventor: FUCHS GERHARD
IPC: F27B3/18
Filed: 1999-02-19
Abstract: In the present invention, there is disclosed a preheater for preheating a fed charging stock (60) into a furnace (1)¿vessel (3), particularly scrap  and comprising a shaft (9) fixed in a frame structure (20). In its upper area the shaft (9) has a closable charging hole (61) for the charging stock (60) and a gas outlet (32) and in its lower area it has a discharge opening for the charging stock (60) and a gas inlet. The shaft walls (34 to 37) delimit a receiving chamber (62) for the charging stock (60) to be heated. According to the invention at least one of the shaft walls (34 to 37) is divided into shaft wall (34 to 37) sections (34/1, 34/2, to 37/1, 37/2), which are independently fixed in the frame structure (20) such that they can be exchanged individually. Disclosed is also a melting unit comprising an electric-arc furnace (1) including a furnace (1) vessel (3) with a vessel (3) cover (4), a cover (4) one first section (7) and a cover (4) one second section (8), from which said first section (7) includes at least one opening (14) for introducing and electrode (12) therein and the second section (8) includes said charging stock (6( preheater (60) the shaft (8) supporting frame structure (20) of which is fastened in a holding-down device (21) wherein said holding-down device (21) and the vessel (3) can slide horizontally relative to each another.
Patent CZ-300384-B6 (CZ)
Title: Shapable prepreg
Inventor: VALLITTU PEKKA
IPC: A61K6/884
Filed: 1999-02-15
Abstract: The present invention relates to a shapable prepreg comprising fibres and a polymeric matrix (see Figure). The polymeric matrix is a multiphase matrix comprising: a first matrix component consisting of a monomer or a dendrimer; and a second matrix component consisting of high molecular weight organic molecules, said second matrix component forming a sticky membrane of the prepreg with an interpenetrating polymer network (IPN) bonding to the first matrix component. Preferably, the prepreg further comprises a third matrix component consisting of high molecular weight organic molecules, said third component being distributed between the fibres.
Patent CZ-299253-B6 (CZ)
Title: Isoindoline derivative, its use for preparing a medicament and pharmaceutical composition containing such derivative
Inventor: MAN HON-WAH
IPC: A61P37/02
Filed: 1999-03-16
Abstract: In the present invention, there is disclosed an isoindoline derivative of the indicated general formula in which Y represents oxygen or Hi2, Re1 and Re2 denote independently on each other a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms and Re3 denotes a hydrogen atom an alkyl group containing 1 to 4 carbon atoms, or a benzyl group, or a substantially chirally pure (S)-isomer, substantially chirally pure (R)-isomer or acid addition salt thereof, as well as the use of the derivative in the preparation of a medicament intended for reduction of undesired concentrations of inflammatory cytokines and treatment of inflammations and autoimmune diseases in a mammal.
Patent CZ-301464-B6 (CZ)
Title: Piperazine and piperidine compounds, process of their preparation and pharmaceutical preparations in which the compounds are comprised
Inventor: FEENSTRA ROELOF W
IPC: A61P43/00
Filed: 2001-05-10
Abstract: The present invention relates to compounds of the general formula I, their salts and prodrugs, further to a process for preparing such compounds by reacting a compound of the general formula Ia with a compound Q-Hal, and to a pharmaceutical composition in which the compounds are comprised. The compounds according to the invention exhibit interesting pharmacological properties due to a combination of (partial) agonism towards the members of the dopamine D2-receptor subfamily and affinity for relevant serotonin and/or noradrenergic receptors. Therefore, the above-described compounds can be used for the treatment of corresponding diseases, particularly central nervous system disorders, anxiety, depression, ParkinsonÆs disease and addiction.
Patent SK-285308-B6 (SK)
Title: Medicament for treating sleeping disorders
Inventor: CHEETHAM SHARON CRAWFORD
IPC: A61K31/00
Filed: 2000-03-17
Abstract: Disclosed is the use of a compound of formula (I) including enantiomers and pharmaceutically acceptable salts thereof in which R1 and R2 are independently H or methyl for the manufacture of a medicament for treating sleeping disorders including sleep apnoea and snoring. A preferred compound of formula (I) is N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride (sibutramine hydrochloride).
Patent SK-285669-B6 (SK)
Title: Ecteinascidin compound, pharmaceutical composition comprising the same and its use
Inventor: RINEHART KENNETH L
IPC: A61K31/00
Filed: 1999-04-05
Abstract: Described are ecteinascidin compounds Et 757 and Iso-Et 743, pharmaceutical compositions comprising them and their use for the preparation of medicaments for the treatment of mammalian leukaemia, mammalian melanoma and mammalian lung carcinoma.
Patent SK-288494-B6 (SK)
Title: Sensor system for detecting the position of a radiation source
Inventor: BALARA MILAN
IPC: G01T1/08
Filed: 2014-07-30
Abstract: Sensor system for detecting the position of the radiation source is formed by a base plate (1), the profile bar (2), the sensors (3) of radiation, transparent cover (4), forming a block (5), multi-channel communications link (6) and signal lines ( 7). The base plate (1) is a fixed profile bar (2), which corners are arranged sensors (3) of radiation mounted on the base plate (1). On it is mounted forming unit (5) and from the emerging multichannel communications link (6). The base plate (1) of the profile bar (2) and sensors (3) of radiation is fitted over and fixed to a transparent cover (4). Sensors (3) to the radiation of signal lines (7) connected to the forming unit (5) by the base plate (1).
Patent JP-7064058-B6 (JP)
Title: 切断刃又はガードの歯を形成する方法
IPC: B21D28/00
Filed: 2020-05-08
Granted: 2022-06-06
Abstract: 本発明は、切断刃又はガードの複数の歯を形成する方法２００に関し、この方法は、ａ）材料のブランクを採取するステップ２１０であって、ブランクは上部外面及び下部外面を持ち、上記下部外面の少なくとも一部は、実質的に平面であり、上記ブランクの平面を形成する、ステップと、ｂ）第１のダイ４０及び第２のダイ５０を含む切断装置を利用するステップであって、第１のダイは複数の第１の要素４２を含み、第２のダイは複数の第２の要素５２を含み、複数の第１の要素の上面に対して第１の平面６０が規定され、複数の第２の要素の下面に対して第２の平面７０が規定され、複数の第１要素の各上面は、第１平面内にある中央部４４と、第１平面の下方にあるエッジ部４６とを持つ、ステップと、ｃ）下部外面の一部が複数の第１の要素の上部表面を向き、上部外面の一部が複数の第２の要素の下部表面を向くように、ブランクを切断装置に配置するステップ２３０と、ｄ）第１の平面が第２の平面に向かって移動し、第２の平面を通過するように、第１のダイ及び第２のダイを互いに対して移動させるステップ２４０であって、複数の第１の要素の各要素が、複数の第２の要素の隣接する要素の間を少なくとも部分的に通過し、複数の第１の要素の位置に対応する切断刃又はガードの歯８０が形成され、上記歯が、上記ブランクの下部外面から形成された下部外面を持つ、ステップと、ｅ）曲げ装置３０を利用して、ステップｄ）の後にブランクの平面の下に延びる切断刃又はガードの歯のエッジ部分８２を、ブランクの平面に向かって曲げるステップ２５０とを有する。
Patent BR-PI0208367-B8 (BR)
Title: composição farmacêutica para o tratamento de infecções oculares, para aplicação local, processo para a preparação de uma composição farmacêutica de colírio, adequada para aplicação local em oftalmologia, e, utilização de azitromicina
Inventor: Frédéric Pilotaz
IPC: A61K31/7052
Filed: 2002-04-11
Abstract: "composição farmacêutica de tratamento de infecções oculares por aplicação local, processo de preparação de uma composição farmacêutica de colírio, e, utilização de azitromicina". a invenção refere-se a uma composição farmacêutica para a prevenção e/ou o tratamento de infecções oculares que deve ser utilizado em aplicação local. ela visa particularmente uma tal composição que se apresenta sob a forma de um colírio distribuível gota a gota em que um agente antibiótico da classe dos macrolídeos, como a azitromicina, está em solução em um veículo oleoso. este veículo é notadamente do tipo de produtos essencialmente constituídos de triglicerídeos com cadeia média em que as funções álcool da glicerila são completamente esterificadas pelos ácidos carboxílicos de hidrocarbonetos saturados cuja molécula comporta de 5 a 12 átomos de carbono. trata-se, preferivelmente, de ácidos graxos de cadeia linear compreendendo de 8 a 10 átomos de carbono, como o ácido caprílico e o ácido cáprico. a composição é com vantagem preparada por uma colocação em solução de agente ativo no veículo oleoso efetuada a uma temperatura não ultrapassando 70<198>c.
Patent EP-1417428-B8 (EP)
Title: Gearing assembly
Inventor: SCHAPIRO BORIS
IPC: F16H35/00
Filed: 2002-08-08
Granted: 2005-06-08
Abstract: The axis of a gear is to follow a trajectory having a salient point. To this end, the gear rolls along two stationary toothed racks. A change-over toothing is provided between these two toothed racks. This change-over toothing extends non-smoothly with respect to the toothed racks. Such change-over toothing permits the gear to roll, without jamming, from one of the toothed racks to the other one, with its axis following a trajectory having a salient point.
Patent EP-1772657-B8 (EP)
Title: Pipe arrangement
Inventor: KANIA GUIDO
IPC: F16L9/00
Filed: 2006-09-25
Granted: 2010-11-24
Abstract: The pipe arrangement (1) for carrying fluids and/or gaseous media, in which the pipe arrangement consists of at least one layer encompassing the lumen, has at least one identification element (3) shown from the lumen. The identification element is located on the surface of the layer pointing into the lumen of the pipe arrangement, or may be located in the layer. The identification element may be formed as a coating, an embossing, a memory element, or a bar code. The identification unit may have a color which differs from the layer of the pipe arrangement.
Patent EP-1015787-B8 (EP)
Title: Dispositif d'isolation contre les microvibrations
Inventor: KEMENY ZOLTAN A
IPC: F16F15/06
Filed: 1998-09-25
Granted: 2006-02-01
Abstract: Cette invention concerne un dispositif d'isolation passif contre les vibrations destiné à effectuer la suppression des vibrations à larges bandes. Le dispositif comprend de préférence soit un filtre à ressort vertical, soit un filtre à ressort horizontal ou bien encore une combinaison des deux. Le filtre à ressort vertical peut comprendre un nombre indéfini de rondelles Belleville ou ZK, empilées en série, en parallèle ou suivant n'importe quelle combinaison de ces dernières. Les rondelles ZK sont des rondelles qui comprennent plusieurs anneaux concentriques intégrés de conicité variable. Le dispositif peut également comprendre de manière facultative une vis, une courroie ou un autre dispositif similaire pour ajuster le rapport de forme du ressort vertical. Le dispositif peut en outre également comprendre de manière facultative une vis ou un dispositif similaire pour ajuster la charge statique placée sur le ressort vertical. Le filtre à ressort horizontal peut comprendre un nombre indéfini de supports retenus à l'intérieur d'un logement conique disposé entre deux plaques cylindriques. Le dispositif d'isolation contre les vibrations peut ensuite être placé sous une machine, ou une plate-forme supportant une machine pour l'isoler des vibrations qui, sans ce dispositif d'isolation, se transmettraient du plancher à la machine ou inversement.
Patent BR-PI0503201-B8 (BR)
Title: stents revestidos com blendas poliméricas hidrofílicas, eluidoras de óxido nítrico e s-nitrosotióis
Inventor: ALEXANDER MARRA MOREIRA
IPC: A61F2/82
Filed: 2005-07-28
Abstract: "stents revestidos com blendas poliméricas hidrofílicas, eluidoras de óxido nítrico e s-nitrosotióis". a presente invenção se refere a um dispositivo para implante intracoronário, introduzindo novos stents eluidores de s-nitrosotióis revestidos com multicamadas de polímeros hidrofílicos, utilizado em procedimentos médicos e se refere aos processos de revestimento de stents com polímeros hidrofílicos contendo s-nitrosotióis incorporados. os stents revestidos com polímeros hidrofílicos contendo s-nitrosotióis são capazes de liberar localmente tanto o óxido nítrico como os próprios s-nitrosotióis, por difusão para aplicações em angioplastia coronária, com o objetivo de inibir a reestenose aguda e crônica. os polímeros hidrofílicos utilizados nos revestimentos são poli (álcool vinílico), poli(vinil pirrolidona) blendas de poli(álcool vinílico)/poli(vinil pirrolidona), poli(álcool vinílico)/poli(etileno glicol), poli(vinil pirrolidona)/poli(etileno glicol) e poli(álcool vinílico)/poli(vinil pirrolidona)/poli(etileno glicol). os processos de revestimento incluem processos de imersão dos stents nas soluções poliméricas contendo os s-nitrosotióis e processos de nebulização das soluções poliméricas contendo os s-nitrosotióis sobre a superfície dos stents.
Patent BR-PI0517909-B8 (BR)
Inventor: HIROYOSHI HIDAKA
IPC: A61P9/10
Filed: 2005-11-29
Abstract: The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.
Patent BR-PI0603332-B8 (BR)
Inventor: LLORET MIGUEL ANGEL TÁRREGA I
IPC: E05D15/06
Filed: 2006-05-31
Abstract: The present invention relates to a mechanism for a sliding-type glass pane (1), of those formed by a top guide profile (2), placed against the wall and provided with a rib (21) on which a rolling element (6) moves; a bottom guide (3); a suspension device (4) and top retaining stops (5), in which said suspension device (4) comprises a larger outer plate (41) and two smaller inner plates (42), which define a space between them in which the rolling element (6) is housed and in which the top retaining stops (5) are provided with respective horizontal flats (51) so as to retain the cylinders (7).
Patent BR-PI0621648-B8 (BR)
Title: envoltório de embalagem
Inventor: CHATRINE STRIDFELDT
IPC: A61F13/551
Filed: 2006-05-04
Abstract: envoltório multifuncional. a invenção se refere a um envoltório de embalagem (2) para um artigo absorvente (1), o envoltório (2) compreendendo uma camada protetora (5). a invenção é caracterizada pelo fato de que o envoltório (2) compreende também uma primeira camada funcional (3) anexada à camada protetora (5) dando ao envoltório (2) uma múltipla funcionalidade.
Patent BR-PI0722363-B8 (BR)
Title: patch de correção de cartilagem laminado implantável
Inventor: MATHIES BURKHARD
IPC: A61L27/20
Filed: 2007-12-21
Abstract: patch de correção de cartilagem laminado implantável. a presente invenção refere-se a um dispositivo e método que proveem uma terapia cirúrgica para o tratamento e correção em posição original de lesões e/ou defeitos da cartilagem intra-articular. o dispositivo é um patch de correção de cartilagem laminado implantável que é biocompatível e fisiologicamente absorvível. o patch de correção de cartilagem tem uma primeira camada oclusiva de célula externa, uma segunda camada externa porosa de célula adaptada para ser disposta próxima a um local de ferida do osso subcondral e uma matriz cartilagênica disposta entre a primeira e a segunda camadas. a matriz cartilagênica é um escoadouro para a difusão das células-tronco autólogas e inclui componentes químicos estimulando a geração de cartilagem semelhante ao hialino na presença de células-tronco autólogas. o método da presente invenção proporciona as composições autólogas, que quando usadas em combinação com o patch de correção provê um sistema terapêutico para regenerar a cartilagem intraarticular semelhante ao hialino de substituição.
Patent BR-PI0816076-B8 (BR)
Title: Filme de barreira de oxigênio ativa multicamada e embalagem
Inventor: SCOTT BECKWITH
IPC: B65D65/40
Filed: 2008-07-23
Abstract: FILME MULTICAMADA TENDO CAMADAS DE BARREIRA DE OXIGÊNIO PASSIVA E ATIVA. A presente invenção refere-se a um filme multicamada tendo um núcleo de multicamada de barreira de oxigênio ativa compreendendo pelo menos um de 1) uma camada de barreira de oxigênio ativa é intercalada entre duas camadas de barreira de oxigênio passiva, ou 2) uma camada de barreira de oxigênio passiva é intercalada entre duas camadas de barreira de oxigênio ativa. Em uma concretização, a camada de barreira ativa compreende uma composição que é uma mistura de uma resina termoplástica (A) tendo ligações duplas carbono-carbono substancialmente em sua cadeia principal, um sal de metal de transição (B), e um polímero de barreira de oxigênio (C). Em algumas concretizações, a camada de barreira ativa pode também incluir um compatibilizador (D). As camadas de barreira de oxigênio passiva ajudam a manter as propriedades de barreira de oxigênio do filme multicamada após a capacidade de absorção de oxigênio da camada de barreira ativa ter sido exaurida. Como um resultado, a vida útil do filme pode ser prolongada.
Patent BR-PI0900953-B8 (BR)
Title: dispositivo para cirurgia de olho a laser-óptica, e, método de controle para o mesmo
Inventor: KLAUS VOGLER
IPC: A61F9/01
Filed: 2009-04-22
Abstract: dispositivo para cirurgia de olho a laser-óptica, e, método de controle para o mesmo. um dispositivo para cirurgia de olho a laser-óptica inclui uma fonte (10) de radiação laser de femtossegundos pulsada e também componentes ópticos (12, 14, 16) para guiar a radiação laser e focar a mesma sobre um local de tratamento sobre ou dentro do olho (28), os componentes ópticos incluindo uma pluralidade de lentes (18, 20) arranjadas em sucessão no percurso de feixe da radiação laser. de acordo com a invenção, pelo menos uma (18) das lentes é arranjada de modo a ser ajustável em relação às outras lentes na direção do percurso de feixe. em particular, a lente ajustável é uma primeira lente divergente dos componentes ópticos de expansão por feixe (12). um arranjo de atuação (24) é associado à lente ajustável para seu ajuste, para cujo controle uma unidade de controle (26) é provida, que é que é preparada para acessar dados medidos concernentes à topografia de uma superfície do olho e controlar o arranjo de atuação em uma maneira na dependência da topografia de superfície medida. o dispositivo a laser permite dispensar que uma lente de contato seja colocada sobre o olho.
Patent AU-2006304906-B8 (AU)
Title: Androsterone derivatives and method of use thereof
Inventor: LI-XI YANG
IPC: A61K31/56
Filed: 2006-10-18
Granted: 2011-11-03
Abstract: The disclosure provides androsterone derivatives. The derivatives of the disclosure are useful in the treatment of androgen- and estrogen-associated diseases and disorders,, including breast cancer.
Patent EP-1144623-B9 (EP)
Inventor: KREUTZER ROLAND
IPC: C12N15/11
Filed: 2000-01-29
Granted: 2003-03-05
Abstract: A new method to inhibit the expression of a predetermined target gene in a cell, comprises introducing an oligoribonucleotide with double stranded structure (dsRNA) or a vector coding for the dsRNA into the cell, where a strand of the dsRNA is at least in part complementary to the target gene. ACTIVITY : Antiviral; cytostatic; anti-prion. MECHANISM OF ACTION : Double stranded RNA inhibitor of gene expression.
Patent BE-1025269-B9 (BE)
Title: Dispositif et methode pour detecter qu’une personne alitee quitte son lit ou a chute.
Inventor: KAPLAN PHILIPPE
IPC: A61B5/11
Filed: 2017-09-29
Granted: 2019-01-09
Abstract: La présente invention concerne un dispositif (10) et une méthode pour déterminer un risque de chute ou une chute d’une personne alitée. L’invention comprend une analyse séquentielle de la distance entre une caméra (20) et les objets présents dans le champ de vision (50) de la caméra. En fonction des variations de distances mesurée, et de leurs localisations au sein de l’espace (60) surveillé, un signal d’alerte peut être généré.