baber/WOPTO huggingface dataset:
Patent NL-960031-I1 (NL)
IPC: A61K38/095
Filed: 1996-12-18
Abstract: A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50  mu g agent/ mu mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Patent DE-122005000043-I1 (DE)
Inventor: LUTHER R
IPC: A61P29/00
Filed: 1996-06-26
Abstract: Disclosed is the use of an omega-conopeptide in the manufacture of a medicament for inhibiting progression of neuropathic pain disorders.
Patent LU-90969-I2 (LU)
IPC: A61K31/335
Filed: 2002-10-02
Abstract: Topical ophthalmic formulations of the invention contain as an active ingredient 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid or a pharmaceutically acceptable salt thereof. The formulations are useful for treating allergic eye diseases such as allergic conjunctivitis, vernal conjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis.
Patent LU-91014-I2 (LU)
IPC: C12Q1/68
Filed: 2003-03-18
Abstract: (1) Protein compsn. (free from other proteins) showing a biological activity of Factor VIIIC and being a complex of an 80 kd and 77 kd protein calcium bridged with a 92.5 kd protein is new. (2) Human protein compsn. comprising 1 or 2 polypeptides of 67-80 kd and having an amino acid sequence of formula (I) in the N-terminal half of the polypeptide and having a biological activity of Factor VIIIC is new. (3) Human protein compsn. comprising a polypeptide of 92.5 kd and having an amino acid sequence of formula (II) in the N-terminal half of the polypeptide and having a biological activity of Factor VIIIC. (4) Monoclonal antibody prepd. with a protein compsn. as defined in paragraphs (1)-(3) is new. (5) Detection of a polynucleotide sequence encoding for at least part of Factor VIIIC comprises hybridising it, in single-stranded form, with a probe (III) and then isolating polynucleotide duplexing with the probe.
Patent ES-2400655-R1 (ES)
Title: Captador solar cilindro-parabolico.
Inventor: MARTINEZ SALCEDO JOSE
IPC: F24S23/74
Filed: 2011-09-23
Abstract: Captador solar cilindro-parabólico. La invención se centra en la estructura soporte del captador, en la que se define un núcleo tubular (7) que presenta una configuración triangular, a base de chapas metálicas (8), unidas entre sí mediante remaches (11), sobre la que se fija la estructura de las costillas, a base de perfiles, tubos y elementos de unión, ensamblados mediante remachado. Se consigue mediante la estructura descrita, un captador de fácil montaje, que asegura una geometría fiable y reproducible, eliminando la necesidad de laboriosos procesos ulteriores de ajuste. Todo ello con una ocupación volumétrica mínima en situación de transporte y almacenaje.
Patent ES-2402642-R1 (ES)
Title: Sistema motriz para bicicletas, triciclos y vehiculos de traccion a pedales
Inventor: BACAICOA CASTELLANOS RODOLFO
IPC: B62M6/55
Filed: 2011-10-26
Abstract: La invención se centra en el hecho de que incorpora un doble eje de accionamiento, en el que participa un eje exterior (10), y un eje interior (11), concéntricos, con sus correspondientes rodamientos, de manera que, las bielas (6) son solidarias al eje interior (11), mientras que el plato o conjunto de platos (5) es solidario al eje exterior (10), mientras que al extremo opuesto (16) de dicho eje exterior (10) se fija solidariamente una corona (17) en la que se define un alojamiento para un buje (18) dotado de un mecanismo de trinquetes que permite que el eje externo (10) gire independientemente del eje interno, pero que, a través de dicho mecanismo de trinquetes, se transmita el movimiento de giro del eje interno al eje externo. La corona (17) está asociada a una segunda cadena (20), que es accionada a través de un piñón (21) que emerge de la carcasa de un grupo moto-reductor (22), asociado al cuadro o chasis del vehículo, grupo moto-reductor alimentado por una batería (25) y controlado por un microprocesador (26) y el correspondiente mando en el manillar.
Patent ES-2418459-R1 (ES)
Title: Relacionando agregacion proteica con supervivencia de levadura
Inventor: VENTURA ZAMORA SALVADOR
IPC: G01N33/542
Filed: 2009-10-09
Abstract: Relacionando agregación proteica con supervivencia de levadura. La invención se refiere a métodos para la identificación de compuestos capaces de prevenir la agregación de polipéptidos propensos a la agregación basados en el uso de proteínas de fusión. Las proteínas de fusión comprenden la proteína de interés y una enzima que es capaz de metabolizar un agente tóxico para la célula. Si el compuesto candidato previene la agregación de la proteína de fusión, el enzima se mantiene soluble y en forma activa, evitando así el efecto tóxico en la célula e incrementando la viabilidad celular respecto a la de células no expuestas al compuesto candidato. La invención también proporciona diferentes polipéptidos que contienen un polipéptido con tendencia a agregar y una enzima, y describe la utilización de los mismos.
Patent ES-2426017-R1 (ES)
Title: Microemulsión que comprende colagenasa y usos
Inventor: MUNOZ MONTANO JUAN RAMON
IPC: A61K9/107
Filed: 2012-03-29
Abstract: Microemulsión que comprenden colagenasa y usos. Microemulsión de colagenasa G recombinante y colagenasa H recombinante, composiciones farmacéuticas y cosméticas, y su uso en el tratamiento de la celulitis.
Patent ES-2427719-R1 (ES)
Title: Cabezal de corte para maquinas de corte.
Inventor: GONZALEZ GARCIA EMILIO
IPC: B23K7/10
Filed: 2012-04-27
Abstract: Cabezal de corte para máquinas de corte.#Especialmente concebido para ser implantado en máquinas de corte, es decir para máquinas destinadas al corte de chapa con bordes achaflanados, la invención permite obtener un cabezal estructuralmente simple, pero a la vez sumamente preciso, evitando posibles desajustes del dispositivo. Para ello, el mismo está constituido a partir de una carcasa, dotada de medios de sujeción articulada del cabezal de corte (6), respecto de un eje perpendicular al eje longitudinal de la carcasa, estando dicho cabezal asociado a una transmisión accionadas mediante un primer motor (9) que se fija en el seno de la carcasa del cabezal.#Perpendicularmente a este primer motor (9) se dispone un segundo motor (12) que acciona una reductora (14), asociada a los medios de fijación (15) del cabezal, definiendo un eje de giro para el cabezal ortogonal al eje de giro del cabezal de corte. En el seno de la carcasa se define una cámara (17) con una ventana inferior (18), con su correspondiente tapa láser (19), cámara en la que está destinado a implantarse un sensor láser (20) de medición, con su correspondiente cilindro láser (21).
Patent ES-2472040-R1 (ES)
Title: Uso de paricalcitol en el tratamiento de la anemia inflamatoria
Inventor: URIOL RIVERA MIGUEL GIOVANNI
IPC: A61K31/593
Filed: 2014-02-11
Abstract: Uso de paricalcitol en el tratamiento de la anemia inflamatoria.#La presente invención describe el uso de paricalcitol, análogo sintético de la vitamina D, en el tratamiento de la anemia inflamatoria, preferentemente en combinación con agentes estimuladores de la eritropoyesis. El uso del paricalcitol para el tratamiento de dicha patología está asociado a un menor requerimiento de agentes estimuladores de la eritropoyesis, a una mejor utilización del hierro y a un incremento en los niveles de eritropoyetina plasmática, por parte de dichos pacientes. La presente invención describe además composiciones farmacéuticas que comprenden paricalcitol en combinación con agentes estimuladores de la eritropoyesis y excipientes farmacéuticamente aceptables, así como el uso de las mismas como medicamentos para el tratamiento de la anemia inflamatoria.
Patent CL-2017000095-S1 (CL)
Title: Bus, cuya fisonomia se conforma por un cuerpo en forma de paralelepipedo recto horizontal de arista frontal superior curvada, el cuerpo en forma de paralelepipedo presenta sus aristas verticales y longitudinales superiores redondeadas.
Inventor: URTEAGA IPARRAGUIRRE PEDRO
Filed: 2017-01-13
Abstract: BUS, CUYA FISONOMÍA SE CONFORMA POR UN CUERPO EN FORMA DE PARALELEPÍPEDO RECTO HORIZONTAL DE ARISTA FRONTAL SUPERIOR CURVADA, EL CUERPO EN FORMA DE PARALELEPÍPEDO PRESENTA SUS ARISTAS VERTICALES Y LONGITUDINALES SUPERIORES REDONDEADAS.
Patent CL-2020002471-S1 (CL)
Title: Medidor eléctrico.
Inventor: DE LUCCHI MICHELE
Filed: 2020-09-24
Abstract: MEDIDOR ELÉCTRICO
Patent SI-0644287-T1 (SI)
Inventor: GROSHENS PIERRE
Filed: 1994-08-31
Abstract: The invention relates to a process for producing a twist directly from fibre material, in that, by means of at least two spinning assemblies (R1, R2) arranged adjacent to one another, individual spun threads (F1, F2) are made and are first brought together in a hollow shaft (11), so as to run through this together in a first thread running direction, and thereafter are guided out of the hollow shaft (11) in a predominantly radial direction, in order then, in accordance with the two-for-one principle, to form and run through, in opposition to the first running direction, a thread balloon rotating about the spinning assemblies and to be fed through a winding assembly through a centring point (37) located in the extension of the hollow shaft, opened fibre material being fed to each spinning assembly through the enveloping surface defined by the thread balloon, and to a device suitable for carrying out this process. <IMAGE>
Patent SI-1589008-T1 (SI)
Title: A crystalline dibenzothiazepine derivative and its use as an antipsychotic agent
Inventor: SNAPE EVAN WILLIAM
IPC: A61K31/554
Filed: 1998-07-28
Abstract: Crystalline 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine may be prepared by crystallising 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine from a non-aromatic solvent such as ethyl acetate, isobutyl acetate, methyl iso-butylketone or methyl tert-butyl ether, preferably in the absence of water. The crystalline material produced may be converted into a pharmaceutically acceptable salt such as a fumarate. The crystalline 11-(4-Ä2-(2-hydroxyethoxy)ethylÜ-1-piperazinyl)-dibenzoÄb,fÜÄ1,4Üthiazepine may be used to treat psychoses.
Patent SI-1140785-T1 (SI)
Title: Method for preparing polyhalogenated paratrifluoromethylanilines
Inventor: ANCEL JEAN-ERICK
IPC: C07B61/00
Filed: 1999-12-10
Abstract: The invention concerns a novel method for preparing polyhalogenated paratrifluormethylanilines particularly useful as reaction intermediates for preparing compositions used as insecticides. The products of the inventive method are obtained by the action of ammonia on polyhalogenated para-trifluoromethylbenzene at a temperature ranging between 150 and 350° C. The inventive reaction can be carried out in the presence of an alkaline halide.
Patent SI-0940995-T1 (SI)
Title: Method and apparatus for extracting chrominance shape information for interlaced scan type image
Inventor: PARK CHEOL SOO
IPC: G06T7/00
Filed: 1999-03-04
Abstract: A method and apparatus for extracting chrominance shape information for an interlaced scan type image, which are used in a video compression coding/decoding system or a video manipulation equipment/system. According to the present invention, in an interlaced scan type image with arbitrary luminance shape information, chrominance shape information is extracted on the basis of four adjacent luminance shape pixels in two lines of the same type field. The present method and apparatus can solve a color bleeding problem in a conventional chrominance shape information extraction method considering no characteristic of the interlaced scan type image. Therefore, the present invention has the effect of significantly improving subjective picture quality. <IMAGE>
Patent TR-199700600-T1 (TR)
Inventor: COLLEN DESIRE JOSE
IPC: C12R1/445
Filed: 1996-01-03
Abstract: A method for producing the derivatives of the invention by preparing a DNA fragment comprising at least the part of the coding sequence of staphylokinase that provides for its biological activity; performing in vitro site-directed mutagenesis on the DNA fragment to replace one or more codons for wild-type amino acids by a codon for another amino acid; cloning the mutated DNA fragment in a suitable vector; transforming or transfecting a suitable host cell with the vector; and culturing the host cell under conditions suitable for expressing the DNA fragment. Preferably the DNA fragment is a 453 bp <u>Eco</u>RI-<u>Hin</u>dIII fragment of the plasmid <u>pMEX602SakB</u>, the in vitro site-directed mutagenesis is performed by an oligonucleotide-directed mutagenesis system using the plasmid <u>pMa/c</u> and the repair deficient E. coli strain WK6MutS, and the mutated DNA fragment is expressed E. coli strain WK6. The invention also relates to pharmaceutical compositions comprising at least one of the staphylokinase derivatives according to the invention together with a suitable excipient, for treatment of arterial thrombosis.
Patent TR-199701572-T1 (TR)
Inventor: EKEROTH MATS
IPC: F16D65/60
Filed: 1996-05-29
Abstract: Içine yerlestirilmis bir gevseklik gerilme ayar kolu olan ve bir fren silindirinden fren gücünü ileten otomatik bir fren kolu (1), frenleme islevini harekete geçiren bir kam mili (2) üzerine monte edilmistir kam miline (2) asinmayi gösteren bir cihaz görevi yapmak üzere, bir kodlanmis disk (10) takilmis olup, diskin mahfazasi (9,11) da fren koluna veya fren kolunda sabit bir noktaya takilmistir. Kodlu diskte daire seklinde bir çok kodlanmis yol ve her bir kodlu yolda da esit uzunlukta manyetik alanlar bulunur. Mahfazanin kapaginda (11) kodlanmis yollarin sayisi kadar yer saglayan elementler (15) olup, her bir bosluk elementi mukabil kodlu yoldaki manyetik alanlari algilayacak sekilde düzenlenmistir. Bu elementlerden gelen sinyaller, disk ile kapak arasindaki göreceli konumu gösterir.
Patent TR-199800120-T1 (TR)
Inventor: KRINNER KLAUS
IPC: E04H12/22
Filed: 1996-07-18
Abstract: PCT No. PCT/EP96/03179 Sec. 371 Date May 20, 1998 Sec. 102(e) Date May 20, 1998 PCT Filed Jul. 18, 1996 PCT Pub. No. WO97/05350 PCT Pub. Date Feb. 13, 1997An anchoring apparatus for securing a pole into ground, which includes a tubular section being retained in the ground for supporting the pole. A support element is disposed on the open end of the tubular member, for supporting the pole proximate to the open end. The support element includes an annular outer member, which is rotatably disposed on the tubular section, and includes a support aperture eccentrically offset with respect to the center of the outer member. An annular inner member is rotatably disposed within the support aperture, and includes a receiving aperture eccentrically offset with respect to the center of the inner member, for supporting the pole. The outer member and inner member are respectively rotatable to vary the positions of the support aperture and the receiving aperture, so as to selectively tilt the poles longitudinal axis to a desired position with respect to the direction of the longitudinal axis of the tubular section.
Patent TR-199800586-T1 (TR)
Inventor: JAEGER JOACHIM
IPC: F04B9/14
Filed: 1996-10-04
Abstract: Isbu bulus, bir akiskan içinde yüksek basinç olusturma islevini yerine getiren minyatür hale getirilmis bir cihaz ile ilgilidir. Bulusa göre cihaz,bir silindir içine yer degistirebilir sekilde bir oyuk piston (57) ve oyuk piston (57) tarafindan yönlendirilen ve oyuk piston (57)'ye nazaran eksensel olarak hareket edebilecek sekilde monte edilmis bir supap elemani (58)'den meydana gelir. Subap elemani (58), oyuk piston (57)'nin bir ucunda, oyuk piston (57)'nin içinde ya da ucunun hemen karsisinda yerlestirilmistir. Cihaz, mekanik olarak çalisan bir yüksek basinçli atomizör içinde kullanilir.
Patent AT-E263928-T1 (AT)
Inventor: KROELL HARALD DIPL-ING
IPC: F15B11/028
Filed: 2000-01-08
Granted: 2004-04-15
Abstract: The system pressure is adjusted by simultaneously operating a pressure limiting valve (2) on the pressure generator side and a press switch on the pressure consumer side. All system pressured detected by a pressure sensor (3) are signalled to a microcontroller (5). The system pressure at the pressure limiting valve is set using a positionable adjustment element (12) having a position switch (10) which signals to the microcontroller the start of the adjustment process.  A check valve in the consumer-side pressure line (8) is simultaneously unblocked to create a uniform pressure between the pressure generator side and the pressure consumer side.
Patent AT-E283178-T1 (AT)
Inventor: NAUMANN MICHAEL
IPC: B60K28/14
Filed: 2000-06-17
Granted: 2004-12-15
Abstract: The battery disconnection device has a switching device (20) for operation of a cut-out switch (19) in response to a signal from a control device (21) upon operation of a control switch, with a current limiting circuit (23), for limiting the current supplied to an electrical load which is independent of the onboard electrical network, e.g. a tachograph, contained within a common housing (2,3).
Patent AT-E486942-T1 (AT)
Inventor: DUNICAN L K
IPC: C12N15/09
Filed: 2000-08-23
Granted: 2010-11-15
Abstract: Isolated polynucleotide containing a polynucleotide sequence selected from the group   a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c), and process for increasing metabolic flux through the pentose phosphate cycle by attenuating the pgi gene. <IMAGE>
Patent AT-E285669-T1 (AT)
Inventor: PANZER SIEGFRIED DR
IPC: A01C1/08
Filed: 2000-08-29
Granted: 2005-01-15
Abstract: The loose materials (5) are passed at atmospheric pressure and in the form of a transparent stream through an electron field (3a) produced by an electron accelerator with a beam window (4). The materials make several passes through the electron field to ensure that all particles receive sufficient dosage. An Independent claim is made for the process equipment which includes a process chamber (1) with several zones (1a,1b,1c) and a transverse electron accelerator (2) extending across all three zones. A material storage hopper (6a,6b,6c) is located above each area together with a vibrator (8a,8b,8c) for forming the transparent falling streams. Collecting sluices (9a,9b,9c) are located below each area and a conveyer removes treated material from the final sluice. The first two sluices have a system for conveying material into the next treatment area.
Patent AT-E256055-T1 (AT)
Inventor: SILHAVY FRANTISEK
IPC: B65F3/02
Filed: 2000-09-29
Granted: 2003-12-15
Abstract: Described is a locking device (18) for side-by-side arranged lifting carriers (12, 15) tipping or lifting devices. For the easy manipulation of the locking device (18), when lifting carriers should be blocked during using the pivot arms (6) as well as during using rack catches, is this blocking element (1), for manipulation blocking element (1), connected via remote variable continuity mechanism (3), which can be secured in two positions (a, b) with the pivot arm (6) of the first lifting carriers (12 or 15).
Patent AT-E265326-T1 (AT)
Inventor: TIGGES MARTIN
IPC: B60C23/00
Filed: 2000-10-16
Granted: 2004-05-15
Abstract: The tire pressure regulation device (1) has a rotary device (2) for transfer of a pressure medium from a stationary part to the rotating wheel (3), provided with at least one chamber (14,15) concentric to the wheel rotation axis, defined by stator and rotor rings (4,5) and sealed by sealing rings between the latter. An axial movement gap is provided between the stator and rotor rings, the stator ring having 2 concentric annular grooves (20,21;21,22)coupled to pressure medium control lines (25,27) used for movement of the sealing rings.
Patent AT-E305716-T1 (AT)
Inventor: STADLER GEORG
IPC: H05B3/06
Filed: 2000-12-15
Granted: 2005-10-15
Abstract: The heater (10) has at least one heater element, which is arranged inside a tube with at least two tube sections (12,16,18), which are connected and sealed from the washing water. The first section may be connected to the other tube sections by a bonding agent. Preferably, the first tube section (12) has a larger outer diameter than the other sections. The second tube element (16) may have a mounting contour for the first tube element. An Independent claim is included for a modular system for the heater.
Patent AT-E529767-T1 (AT)
Inventor: ROMAN GIANFRANCO
IPC: G01W1/14
Filed: 2000-02-18
Granted: 2011-11-15
Abstract: A rain sensor is described comprising a tray (1) for the collection of rain water provided on top with evaporation and overflow side windows (4, 22) covered by a perforated cover (5). A finned float (9) is housed in said tray (1) so as to be able to move vertically as a function of the level of the water present in the tray. A permanent magnet (15) supported by said float (9) cooperates with an electric magneto-sensitive switch (16) that is fixed to the tray (1) in order to switch it between a first and a second electric state as a function of the vertical position of the float (9). <IMAGE>
Patent AT-E302043-T1 (AT)
Inventor: GODO JOSEPH
IPC: A61B17/22
Filed: 2000-03-17
Granted: 2005-09-15
Abstract: The apparatus, using ultrasound for therapeutic purposes, consists of a transducer for emitting the ultrasound waves, located inside a chamber containing a liquid aqueous solution of a hydrophilic polymer as a connecting medium. The hydrophilic polymer has a molecular weight of between 10000 and 100000, and is used at a rate of 10 - 50 g/l. The transducer is connected to an ultrasound generator operating in the frequency range of 1 - 5 MHz, and preferably 2 - 3MHz.
Patent AT-E254837-T1 (AT)
Inventor: OORT DICK MARIUS
IPC: A01J5/007
Filed: 2000-01-05
Granted: 2003-12-15
Abstract: A vacuum control system for controlling vacuum while an animal is being milked. The vacuum control system comprises a vacuum pump which is interconnected to a buffer vessel via a vacuum line. Each teat cup of the milking apparatus has a milk line which interconnects the teat cup to the buffer vessel. The teat cup is also interconnected to the vacuum pump via a pulse line which contains a pulsator. A regulator which includes an rpm governor and an electronic filter unit is connected to the vacuum pump and also by the filter unit to a vacuum sensor which, in turn is connected to the vacuum line. The filter unit is connected both to the rpm governor and to an electronic fast-acting control valve which is activated by the regulator on the basis of signals which it receives from the vacuum sensor. If the vacuum decreases in the vacuum line (and thus the buffer vessel) as result of, for example, a teat cup being disconnected from the teat of an animal being milked, the rpm governor causes the vacuum pump to increase its rpm and therefore capacity whereby the vacuum and vacuum line is maintained in a constant value. On the other hand, if the vacuum and vacuum line increases over its desired level, the electronic fast-acting valve is actuated to admit air to the vacuum line and thereby maintain the vacuum therein at a constant desired level.