baber/WOPTO huggingface dataset:
Patent AU-2019204354-A1 (AU)
Title: Identification of tumor-protective epitopes for the treatment of cancers
Inventor: SRIVASTAVA PRAMOD K
IPC: G01N33/573
Filed: 2019-06-20
Abstract: IDENTIFICATION OF TUMOR-PROTECTIVE EPITOPES FOR THE TREATMENT OF Described herein are methods of identifying tumor-specific epitopes from the cancer tissue DNA of cancer patients using both DNA sequencing and bioinformatics techniques. The identification of tumor-specific epitopes provides pharmaceutical compositions with a limited number of tumor-specific peptides suitable for personalized genomics-driven immunotherapy of human cancer. Specifically disclosed herein is a novel index called the Differential Agretopic Index (DAI) for the epitope which allows prediction of whether immunization with a particular epitope will be protective against the tumor. Pharmaceutical compositions and methods of administration are also included.
Patent AU-2019213337-A1 (AU)
Title: Therapies for hematologic malignancies
Inventor: GALLATIN MICHAEL W
IPC: A61P37/00
Filed: 2019-08-06
Abstract: The invention provides methods that relate to a novel therapeutic strategy for the treatment of hematological malignancies and inflammatory diseases. In particular, the method comprises administration of a compound of formula A, wherein R is H, halo, or Cl-C6 alkyl; R' 5 is Cl-C6 alkyl; or a pharmaceutically acceptable salt thereof; and optionally a pharmaceutically acceptable excipient. N R , '0 R - N R (A)
Patent AU-2019219845-A1 (AU)
Title: Intrasaccular device positioning and deployment system
Inventor: LORENZO JUAN
IPC: A61F2/88
Filed: 2019-08-23
Abstract: Abstract Implant deployment systems can generally can include a braided implant that can be detachably attached to a delivery tube by an expansion ring that can be positioned within a notch on an outer surface of the delivery tube near a distal end of the delivery tube. The implant can be positioned within a lumen of the delivery tube and remain attached to the delivery tube as the assembly is fed through a microcatheter to a treatment site. Once the braided implant is implanted, the expansion ring can move from a collapsed configuration that is engaged with the notch of the delivery tube to a deployed configuration that releases the delivery tube, thereby releasing the braided implant from the delivery tube. "SIt o0 tvtA -- ---- ---- ---- ---
Patent AU-2019226137-A1 (AU)
Title: Rebar ring chair
Inventor: BACK STEPHEN JOHN
IPC: E04C5/20
Filed: 2019-09-03
Abstract: Abstract of the description The invention is a plastic bar chair to be used to hold steel reinforcing bars in position during the pouring of concrete. The design of existing plastic bar chairs means they are unable to withstand temporary increases in weight and have a low unit to volume stacking ratio. The chair is designed with strengthening wedges, arches, crossbars and posts and a protrusion free inside surface of the support legs. Page 1 of 3 Drawings \ Figure1 Figure 2
Patent AU-2019226490-A1 (AU)
Title: Measuring replication-associated DNA methylation loss
Inventor: BERMAN BENJAMIN P
IPC: C12Q1/6827
Filed: 2019-03-02
Abstract: Provided are methods for measuring replication-associated genomic DNA methylation loss, using a Solo-WCGW DNA sequence motif (n
Patent AU-2019236313-A1 (AU)
Title: Device, kit, and method for producing medically-deliverable intravenous saline solution
Inventor: SCALISE MICHAEL B
IPC: A61M5/168
Filed: 2019-03-18
Abstract: A device, kit, and method for producing medically-deliverable intravenous saline solution may include supplying water to a housing, pumping the water through the housing while purifying the water, metering concentrated intravenous saline solution into the water to create a medically-deliverable intravenous saline solution, and dispensing the medically-deliverable intravenous saline solution.
Patent AU-2019240677-A1 (AU)
Title: Irrigation control during ablation
Inventor: GOVARI ASSAF
IPC: A61M5/44
Filed: 2019-10-03
Abstract: In one embodiment, an irrigated ablation system includes a probe to be inserted into a chamber of a heart, the probe including an electrode, a temperature 5 sensor to provide a temperature signal indicative of a temperature of a myocardium, and an irrigation channel through which to irrigate the myocardium, a pump to pump an irrigation fluid into the irrigation channel, an RF signal generator to generate RF power to be applied by the electrode to ablate the myocardium, and a controller to receive the temperature signal, calculate a rate of change of the temperature over 10 time based on the temperature signal, calculate an irrigation rate with which to irrigate the myocardium via the irrigation channel based at least on the calculated rate of change of the temperature, and provide an irrigation signal to the pump to irrigate the myocardium with the irrigation fluid at the calculated irrigation rate. Fig. 1 50 MODULE BANK TRACKING 58 22 44 MODULE 18 16 21 20 IRRIGATION TEMPERATURE MODULE \ 55 ABLATION 2 24 MODULE 54
Patent AU-2019258242-A1 (AU)
Title: Anti-inflammatory compound and preparation and use thereof
Inventor: SHEN WANG
IPC: A61P17/00
Filed: 2019-03-21
Abstract: Provided in the present invention is an anti-inflammatory compound, wherein same is characterized by a compound as shown in the following structure (I): The compound is a target that is important for autoimmune activation, and that has a strong inhibitory effect on PDE4 and penetrates the skin easily, and is a new type anti-inflammatory compound that is easily degraded.
Patent AU-2019262696-A1 (AU)
Title: Food supply tracking, verification, and feedback system
Inventor: HICKS RONALD B
IPC: A01K7/02
Filed: 2019-05-06
Abstract: Food supply may be tracked, authenticated, and evaluated by a variety of systems, processes, and techniques. In certain implementations, computer systems at various animal producers in the food supply chain (e.g., ranch and feedlot) may record and generate data regarding an animal (e.g., breed, age, location, hydration regimen, health history, etc.) and report this to a server system, which may process the data in an authenticated manner. Entities further down the chain (e.g., retailers) may access the server system to retrieve information about meat products and use this in sales efforts. Consumers may also retrieve information about meat products so that they may make informed buying decisions. Additionally, feedback may be provided to animal producers regarding the meat, which may encourage them to continue producing quality animals. Data may also be monetized, and a portion reinvested back to the food producer to assist in labor costs associated with system compliance.
Patent AU-2019267350-A1 (AU)
Title: Methods and compositions for targeted editing of polynucleotides
Inventor: LI JIANG
IPC: C12N15/113
Filed: 2019-04-30
Abstract: The present invention relates to methods and compositions for modifying a target site in a DNA molecule. The present disclosure provides a DNA-targeting RNA duplex which comprises a crRNA molecule and a tracrRNA molecule and methods of using these molecules for modification of a target DNA. Modifications include targeted transgene insertion, targeted allelic replacement, and targeted mutagenesis.
Patent AU-2019271948-A1 (AU)
Title: Active Convection Heat Dissipation Structure
Inventor: CHU YUNG-CHING
IPC: H05K7/20
Filed: 2019-11-27
Abstract: An active convection heat dissipation structure is applicable for a vertical network 5 communication electronic device having a housing and printed circuit boards. Top and bottom portions of the housing are furnished with upper and bottom through holes, respectively. The printed circuit board is vertically mounted inside the housing and furnished with heat generating member. The active convection heat dissipation structure includes a chamber inside the housing is a hollow tube shape structure 10 consisted at least of one lateral wall. The chamber has a bottom as air inlet and a top as an air outlet communicated spatially with the air inlet to form a vertical convection path. The air inlet is communicated spatially with the bottom through holes, and the air outlet is communicated spatially with the upper through holes. An outer surface of the lateral wall is attached to the corresponding heat generating member on the printed circuit 15 board.
Patent AU-2019304198-A1 (AU)
Title: Heterocyclic spiro compounds as MAGL inhibitors
Inventor: BRODNEY MICHAEL AARON
IPC: A61P37/00
Filed: 2019-07-10
Abstract: The present invention provides, in part, a compound selected from the group consisting of: 1,1,1,3,3,3-hexafluoropropan-2-yl (3R)-3-{[(cyclopropylmethyl)sulfonyl]amino}-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1,1,1,3,3,3-hexafluoropropan-2-yl (3R)-3-[(cyclopropylsulfonyl)amino]-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1,1,1,3,3,3-hexafluoropropan-2-yl 3-{[(cyclopropylmethyl)sulfonyl]amino}-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate; 1,1,1,3,3,3-hexafluoropropan-2-yl 3-{[(cyclopropylmethyl)sulfonyl]amino}-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate, ENT-1; and 1,1,1,3,3,3-hexafluoropropan-2-yl 3-{[(cyclopropylmethyl)sulfonyl]amino}-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate, ENT-2, and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating MAGL-mediated diseases and disorders including, e.g., pain, an inflammatory disorder, depression, anxiety, Alzheimer's disease, a metabolic disorder, steatohepatitis [e.g. nonalcoholic Steatohepatitis (NASH)], stroke, or cancer.
Patent AU-2019304484-A1 (AU)
Title: Method for preparing protein-fibre concentrates from plant material
Inventor: WNUKOWSKI PIOTR
IPC: A23J1/14
Filed: 2019-07-16
Abstract: The present invention concerns a process wherein native and functional protein-fibre concentrates can be successfully obtained from plant material such as oilseeds, legumes and lentils. This can be achieved by a proper pre-treatment of the plant material, followed by a method of partial extracting water-soluble proteins under mild and non-destructive conditions using an aqueous solvent, followed by purification of the solid residue using a novel combination of GRAS organic solvents.
Patent AU-2019313456-A1 (AU)
Title: Use of a cationic polysaccharide compound as a fungicide, pesticide, algaecide, dessicant and for extending the shelf life of fruits and vegetables
Inventor: KIJLSTRA JOHAN
IPC: A01N3/00
Filed: 2019-07-30
Abstract: The invention relates to the use of known cationic polysaccharide compounds as fungicides, pesticides, algaecides, dessicants and for extending the shelf life of fruit and vegetables.
Patent AU-2019321208-A1 (AU)
Title: Sequencing algorithm
Inventor: IMELFORT MICHAEL
IPC: C12Q1/6806
Filed: 2019-08-12
Abstract: The invention relates to a method for determining a sequence of at least one target template nucleic acid molecule using non-mutated sequence reads and mutated sequence reads. The invention also relates to a method for determining a sequence of at least one target template nucleic acid molecule in a sample involving controlling or normalising the number of target template nucleic acid molecules in the sample. The invention also relates to a computer programme adapted to perform the method, a computer readable medium comprising the computer programme, and computer implemented methods.
Patent AU-2019339344-A1 (AU)
Title: Compositions for the treatment of disease with immune stimulatory conjugates
Inventor: ODEGARD VALERIE
IPC: A61K47/68
Filed: 2019-09-11
Abstract: Methods and conjugates are disclosed for alleviating toxicity(ies) associated with administration of immune-stimulatory conjugates, and in particular for alleviating toxicity(ies) associated with intravenous administration of such conjugates.
Patent AU-2019347770-A1 (AU)
Title: Methods and compositions for bioprotection of potatoes from Streptomyces scabies
Inventor: MABOOD FAZLI
IPC: A01N43/82
Filed: 2019-09-27
Abstract: The present invention relates to compositions having antimicrobial activity against
Patent AU-2019369845-A1 (AU)
Title: Emulsion preparation and preparation method thereof
Inventor: DOI YUSUKE
IPC: A61P35/00
Filed: 2019-11-01
Abstract: Provided is a water-in-oil (w/o) type emulsion preparation stably containing three types of four-CTL epitope-joined peptides. Also provided is a method for efficiently preparing the w/o emulsion preparation containing three types of four-CTL epitope-joined peptides. The present invention provides a w/o emulsion preparation stably containing three types of four-CTL epitope-joined peptides and also provides a method for efficiently preparing the w/o emulsion preparation. Also provided are an improved method and device for preparing the preparation.
Patent AU-2019391016-A1 (AU)
Title: Small molecule degraders of helios and methods of use
Inventor: VERANO ALYSSA
IPC: A61K31/4545
Filed: 2019-12-03
Abstract: Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that may cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders characterized or mediated by aberrant protein activity.
Patent AU-2019400907-A1 (AU)
Title: Method for attaching a heat-dissipating piece of equipment, spacecraft wall and spacecraft
Inventor: WALKER ANDREW
IPC: B64G1/50
Filed: 2019-12-18
Abstract: Invention relates to a method for attaching a heat-dissipating piece of equipment and a capillary heat pipe to a panel of a wall of a spacecraft, said method comprising the following steps: a) positioning (18) a capillary heat pipe on part of the panel; b) attaching (26) female attachment bodies to the panel, the female attachment bodies projecting with respect to the capillary heat pipe; c) placing (38) a thermally-conducting and self-curing paste over part of the capillary heat pipe or over a heat-dissipating piece of equipment; d) placing (46) a heat-dissipating piece of equipment on the thermally-conducting and self-curing paste and on the female attachment bodies, said heat-dissipating piece of equipment bearing against and being in direct contact with the female attachment bodies, and e) attaching (48) the heat-dissipating piece of equipment and said capillary heat pipe to the panel by attaching male attachment elements to the female attachment elements.
Patent AU-2019404639-A1 (AU)
Title: Modified orthopoxvirus vectors
Inventor: BELL JOHN C
IPC: C12N15/24
Filed: 2019-12-20
Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences, amenability for large scale manufacturing, and safety.
Patent AU-2019428193-A1 (AU)
Title: Aqueous suspension compositions, formulations, and water dispersible dry compositions comprising 16alpha-bromo-3beta-hydroxy-5alpha-androstan-17-ketone and hydrates, derivatives, and analogs thereof
Inventor: GE YU
IPC: A61P5/44
Filed: 2019-12-31
Abstract: Unusual and unexpectedly stable aqueous suspension formulation and water dispersible dry composition of the following formula (I) compounds. It causes little or no injection site irritation and has superior properties over non-aqueous formulations. It stimulates autophagy, enhance innate immunity, down-regulates unproductive inflammation and exerts a The immune bias. It demonstrates better efficacy in both in vitro and in vivo models.
Patent AU-2019454278-A1 (AU)
Title: Estimating the fidelity of quantum logic gates and quantum circuits
Inventor: BOIXO CASTRILLO SERGIO
IPC: G06N10/00
Filed: 2019-10-30
Abstract: Methods, systems and apparatus for estimating the fidelity of quantum logic gates. In one aspect, a method includes defining multiple sets of random quantum circuits; for each set of random quantum circuits: selecting an observable for each element in the set of random quantum circuits, wherein each selected observable corresponds to a respective element of the set of random quantum circuits and is dependent on the element to which it corresponds; estimating a value of a polarization parameter for the set of random quantum circuits, comprising performing a least mean squares minimization based on multiple expectation values, wherein each expectation value comprises an expectation value of a respective selected observable with respect to an output of an experimental implementation of a random quantum circuit corresponding to the respective selected observable; and processing the estimated polarization parameter values to obtain an estimate of the fidelity of the n-qubit quantum logic gate.
Patent AU-2019459210-A1 (AU)
Title: Method and system for real-time automated identification of fraudulent invoices
Inventor: HAYMAN LIRON
IPC: G06N20/00
Filed: 2019-07-31
Abstract: Known fraudulent invoice data, including defined and known fraudulent invoice feature data, is used to train a machine learning-based fraudulent invoice detection model to generate a fraudulent invoice score for invoices indicating a determined probability that a given invoice is fraudulent. The machine learning-based fraudulent invoice detection model is then used to generate a fraudulent invoice score for subsequent invoices before those invoices are paid by, and in some cases before the invoices are provided to, the parties being asked to pay the invoices. The fraudulent invoice score for the subsequent invoice is then used to determine if the subsequent invoice should be passed on to the parties being asked to pay the invoices for payment, or if one or more protective actions should be taken.
Patent AU-2019479110-A1 (AU)
Title: Fiber slack storage within a deployment system handle
Inventor: BEARD MATTHEW S
IPC: A61F2/95
Filed: 2019-12-18
Abstract: According to an example of the present disclosure, an apparatus to store slack in a system line for a medical device is disclosed. The apparatus comprises a plurality of slack pockets arranged in series. The system line is configured to form a slack loop into each slack pocket, the plurality of slack pockets isolating the slack loops from each other. The plurality of slack pockets are configured such that when tension is applied to the system line, slack is dispensed by each slack loop straightening from each slack pocket without tangling with another one of the slack loops.
Patent WO-2021237268-A1 (WO)
Title: Method and system for controlling drill functionality
Inventor: INNES CHRIS
IPC: E21B44/00
Filed: 2020-05-29
Abstract: Disclosed herein are a method and system for controlling a drill rig by utilising a drill control module. A drill control module for controlling functionality of a drill rig comprises: a processor; a storage medium for storing a computer program having instructions that when executed on the processor perform the method steps of: drilling a hole by repeatedly: activating a hammer drilling mode for a predefined interval parameter, said activated hammer drilling mode causing a drill bit of said drill rig to impact a surface using a hammer drilling technique; and activating a pause interval for a predefined interval time, during which said drill bit reduces engagement with said surface.
Patent AU-2020201680-A1 (AU)
Title: Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
Inventor: UNGER EVAN C
IPC: A61K39/395
Filed: 2020-03-06
Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms. See Fig. 1A.
Patent AU-2020203804-A1 (AU)
Title: Locking top for vessel having a neck
Inventor: REY GAËTAN
IPC: A61J1/14
Filed: 2020-06-09
Abstract: The invention relates to a locking top for blocking a 
stopper in the neck of a vessel. The top comprises an outer 
body, and a cage (20) which is configured to fit into and 
lock axially in the outer body. The cage (20) comprises an 
upper ring (21), a plurality n of branches (22) connected 
to the upper ring (21), n/2 median bridges (25) and n/2 
lower bridges (26) arranged in alternation on the periphery 
of the cage (20), each connecting together two adjacent 
branches (22). When the top is in an intermediate holding 
position in which the stopper is partially pushed into the 
neck, the lower bridges (26) surround, at least in part, a 
collar of the neck; the median bridges (25) located, in an 
axial direction, between the upper ring (21) and the lower 
bridges (26) are designed to form an open space between 
them and the collar.
[Fig. la] 
100 
lo30 20 
30 10 
12 
202 
24 
201 
200 
[Fig. 1b] 
20 
100 
3- 
-- 12 1 0 }10 
13 
201 
200
Patent AU-2020204474-A1 (AU)
Title: Method for color maintenance and enhancement of tattoo
Inventor: Wang wan-ting
IPC: A61L15/28
Filed: 2020-07-06
Abstract: Method for color maintenance and enhancement of tattoo 
The present invention is a waterproof and air-permeable moist dressing 
which moisturizes and enhances color for aftercare of fresh tattoo.  
Therefore, the present invention is capable of providing professional and 
medical repair, protection, isolation, and absorbing wound exudates and 
tattoo inks after tattooing to improve the aesthetical beauty of the tattoo.
1/2 
101 @102 
103 
Figure 1 
10 
10132 
Figure 2
Patent AU-2020223681-A1 (AU)
Title: Plant regulatory elements and uses thereof
Inventor: FLASINSKI STANISLAW
IPC: C12N9/10
Filed: 2020-08-26
Abstract: The invention provides DNA molecules and constructs, and their nucleotide 
sequences, useful for modulating gene expression in plants, and for specifying intracellular or 
extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant 
parts, and seeds, comprising the DNA molecules operably linked to a heterologous 
transcribable polynucleotides are also provided.
Patent AU-2020232306-A1 (AU)
Title: Ready-to-use injectable formulations
Inventor: JOSHI VIJAYA BHARTI
IPC: A61K47/14
Filed: 2020-03-05
Abstract: The invention describes a ready-to-use injectable cephalosporin composition with reasonable viscosity, resuspendability, and syringeability attributes for injection as an antibiotic for animals.
Patent AU-2020244384-A1 (AU)
Title: A component for conveying gases
Inventor: GRAHAM PETER KENNETH
IPC: A61M16/08
Filed: 2020-09-28
Abstract: This invention provides for a component forming a part of a breathing tube, or forming the 
breathing tube, for example as a part of a breathing circuit for respiratory therapy. The 
5 component comprising a tubular body having a foamed wall. The foamed wall can be formed 
from extrusion of a single extrudate. The foamed wall is of a sufficient minimum optical 
transparency such that, in use, there is enabled the visual detection of a liquid (or condensate that 
may have formed) within the tubular body.
Patent AU-2020250263-A1 (AU)
Title: Pharmaceutical compositions comprising n-(3,5-dimethoxyphenyl)-n'-(1-methylethyl)-n-[3-(1-methyl-1h-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Inventor: BROGGINI DIEGO FERNANDO DOMENICO
IPC: A61P35/00
Filed: 2020-10-08
Abstract: The invention relates to pharmaceutical compositions comprising N-(3,5-dimethoxyphenyl)
N'-(1-methylethyl)-N-[3(1-methyl-iH-pyrazol-4-yl)quinoxalin-6- yl]ethane-1,2-diamine, or a 
5 pharmaceutically acceptable salt thereof or a solvate thereof; to processes for the preparation 
of said compositions and to the use of said compositions for the manufacture of a medicament 
for the prophylaxis of or the treatment, in particular the treatment, of diseases, e.g. cancer.