baber/WOPTO huggingface dataset:
Patent DK-630586-D0 (DK)
Inventor: KARJALAINEN ARTO JOHANNES
IPC: C07D233/64
Filed: 1986-12-29
Abstract: The invention provides compounds of the formula:   <IMAGE> (I) wherein R1, R2 and R3, which can be the same or different, are each hydrogen, chloro, bromo, fluoro, methyl, ethyl, methoxy, amino, hydroxy or nitro; R4 is hydrogen or alkyl of 1 to 7 carbon atoms; -X- is   <IMAGE>    R5 is hydrogen, hydroxy or -OR6; and R6 is alkyl of 1 to 7 carbon atoms or aryl of 6 to 10 carbon atoms; and their non-toxic pharmaceutically acceptable acid addition salts and mixtures thereof. Processes for the preparation and use of the subject compounds are described, as are novel pharmaceutical compositions comprising at least one of the subject compounds or their salts. The compounds and their non-toxic salts exhibit valuable pharmacological activity and are useful in the treatment of mammals, e.g., as anti-ulcer or anti-hypertensive agents. Furthermore, they are useful as diuretic, sedative, analgesic, anti-inflammatory and tranquilizing agents.
Patent DK-705888-D0 (DK)
Inventor: HERTER ROLF
IPC: C07D403/12
Filed: 1988-12-19
Abstract: 6-Substd. phenyl-pyridazin-3-one derivs. of formula (I) and their salts are new: A=(i)-(iv), R1 = NO2, NH2, OH, CN or halo; R2 = H, Me or CH2OH; R3 = H, 1-6C alkyl (opt. substd. by an OH or NH2 gp.); opt. substd. aryl or heteroaryl; CN; acyl; opt. substd. aroyl; COOH or 1-6C alkoxycarbonyl; m = 1-3; n = 2-4.
Patent HU-911394-D0 (HU)
Title: Apparatus for storing and transporting tubes
Inventor: KOCH ROBERT
IPC: B65D85/00
Filed: 1990-08-23
Abstract: The invention concerns equipment for storing and shipping pipes with several superposed pipe supports. To simplify manufacture and lower its costs and further to achieve versatility, the pipe supports (5) each comprise a long, integrated molding (120) with several cylindrical clearances (122, 124) present on two opposite sides, for several pipes, or several short assembled molded segments (2) with at least one cylindrical clearance (6,8) for the pipes, on opposite sides. The integral molding (120) and the molded parts (2) are provided with a central duct (10) extending between and transverse to the bilateral clearances and passing through the molding or the molded segments. The integral molded segments are plugged in geometrically locking manner onto a strip or a hollow shaped section (4). The intrgral molded segment (120) preferably is attached by injection molding to the hollow shaped section.
Patent HU-913011-D0 (HU)
Title: Method for producing inhibitors of calcium ingestion
Inventor: DINERSTEIN ROBERT JOSEPH
IPC: A61P37/00
Filed: 1991-09-19
Abstract: This invention relates to 1-phenyl-3-phenyl-2-propyne-1-ones, and pharmaceutical compositions containing these compounds as active ingredients useful as calcium uptake inhibitors in leukocytes and thrombocytes, and the process for their preparation.
Patent HU-896017-D0 (HU)
Title: Process for waterproofing of cement products
Inventor: MIKO HANS-JUERGEN
IPC: E04B/
Filed: 1989-11-20
Abstract: A process is proposed for the impregnation of cement products, preferably pressed after forming, especially under the action of heat, in particular fibre-reinforced cement products, before the setting thereof, in which a preferably aqueous plastics dispersion and, subsequently thereto, a preferably aqueous wax dispersion, especially a paraffin dispersion, is applied to the products wet from the mould. Advantageously, the wax dispersion is here applied within about 2 minutes after the application of the plastics dispersion; advantageously, above all the plastics dispersion, and preferably both the plastics dispersion and the wax dispersion, are rolled on.
Patent NO-900270-D0 (NO)
Inventor: MUELLER WALTER
IPC: A61K45/08
Filed: 1990-01-19
Abstract: The invention relates to a surface treatment system consisting of an impermeable backing layer, of an agent-containing matrix and of a protective layer which can be detached again, where the matrix contains:
 a. an antineoplastic agent
 b. a self-adhesive polyacrylate
 c. a water absorber
 and where appropriate
 d. a non-adhesive hydrophilic polyacrylate
 e. an emollient and/or penetration promoter.
Patent NO-900732-D0 (NO)
Inventor: GOTO GIICHI
IPC: A61K31/36
Filed: 1990-02-15
Abstract: An aralkylamine compound of the formula <CHEM> wherein R<1> means a hydrogen atom or a lower alkyl group; R<2> means an aromatic group which may be substituted; R<3> means a hydrogen atom, a lower alkyl group or an aromatic group which may be substituted; n means an integer of 0 to 7; ring A means a five- through eight-membered cyclic group which may be substituted and may contain one or two hetero atom(s) of O and S atoms as the ring-constituents; and ring B means a benzene ring which may be substituted, or a salt thereof, which is useful as an cholinesterase inhibitor and a cerebral function ameliorating agent.
Patent NO-912864-D0 (NO)
Inventor: BREDEHORST REINHARD
IPC: A61K47/48
Filed: 1991-07-22
Abstract: A method for site-specific in-vivo activation of a prodrug in an animal using an activator-targeting moiety conjugate to localize an activator at a predetermined site of use and a prodrug compound that is converted to an active drug in the presence of the activator. In the preferred embodiment, the targeting moiety, the activator, and the prodrug demonstrate little or no immunogenecity in the animal being treated. The targeting moiety is relatively specific for binding to the target tissue than to non-target tissue. The activator is not found or present in only small amounts in circulation or in non-target tissue, does not have a substrate for its activity in circulation or in non-target tissue, can be linked to the targeting moiety, and is capable of converting the prodrug to an active drug. The prodrug is selected for its ability to exert a cytotoxic activity on the target tissue after conversion by the activator.
Patent NO-913757-D0 (NO)
Inventor: DESFORGES MALCOLM
IPC: A23L27/30
Filed: 1991-09-25
Abstract: A non-gelling water-soluble sugar beet fibre having serum cholesterol-lowering properties is obtained from sugar beet or sugar beet pulp by extraction with water at temperatures above 70 DEG C, preferably above 90 DEG C, more preferably 95-100 DEG C. Preferably, the starting material is sugar beet pulp from which the sugar has already been extracted in a conventional sugar extraction process.
Patent NO-914864-D0 (NO)
Inventor: COX MICHAEL GRAHAM CAREY
IPC: C06F3/00
Filed: 1991-12-11
Abstract: A pyrotechnic compsn. is claimed which includes ferrophosphorus. Also claimed is the following: a safety match having a head coated in the compsn. The compsn. contains potassium chlorate, a binder, a thickener, a filler and a foaming agent to the exclusion of sulphur, ZnO or a dichromate. Amt. of potatssium chlorate is 40-60 dry wt.%, and the proportion of ferrophosphorus is in excess of 4 dry wt.%. The ferrophosphorus has a particle size of 5-100 microns. The binder is gelatine, or animal glue and is present as 3-12 dry wt.%. The filler is felspar or another siliceous mineral. The compsn. further contains up to 10 dry wt.% of iron oxide as pigment. The density of the formulation when in the form of a wet compsn. is 1.0-1.4 g/cm3.
Patent NO-915011-D0 (NO)
Inventor: KRAEHLING HERMANN
IPC: A61K31/357
Filed: 1991-12-18
Abstract: Pharmacologically active compounds corresponding to the formula I <IMAGE>  in which n represents 2-5, m represents 2-6, R1 denotes hydrogen or lower alkyl, R2 represents an OR4 group in which R4 denotes lower alkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, or R2 represents a <IMAGE>  group in which R5 and R6 independently of one another each denote hydrogen, lower alkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, or R5 and R6, together with the nitrogen atom to which they are bonded, represent a saturated 5- or 6-membered heterocycle, R3 represents a saturated monocyclic or bicyclic hydrocarbon group which is derived from terpenes and has 10 or 11 carbon atoms, and Z represents oxygen or, if R3 is a dihydronopyl group, Z may also represent sulfur, and salts thereof.
Patent NO-923535-D0 (NO)
Inventor: HEITSCH HOLGER
IPC: C07D519/00
Filed: 1992-09-11
Abstract: Compounds of the formula (I) <IMAGE>  in which the symbols have the following meaning:     X represents a monocyclic radical having 3, 4 or 5 ring atoms, R<1>, R<2>, R<3>, R<4>, R<5>, R<12> and R<13> is, for example, an alkyl radical   q is zero or 1   L is, for example, the methylene group   A is the radical, for example, of a heterocycle are highly effective as antagonists of angiotensin II receptors. They can be used as pharmaceuticals or diagnostics.
Patent NO-924077-D0 (NO)
Inventor: VLIEG KLAES PIET
IPC: H04L9/32
Filed: 1992-10-21
Abstract: Known methods for authenticating communication participants add a code word to a command signal, which code word is a crytographic function of the command signal and a key value which in its turn is a function of a master key value and a change code word. The master key value has a permanently fixed value, in contrast to the change code word which serves to change the key value. The method according to the invention makes use of a key value which is a function of at least one previous key value, the master key value with the permanently fixed value, which, once it has been discovered or leaked, substantially weakens the encryption, no longer being required. <IMAGE>
Patent NO-924921-D0 (NO)
Inventor: KRONE VOLKER
IPC: A61K47/48
Filed: 1992-12-18
Abstract: alpha - or  beta -linked polyaspartamide derivatives of the general formula I <IMAGE> in which R<I>, R<II>, R<III>, R<IV>, r, s, t, u and v have the meanings indicated, are described. They adsorb bile acids and can be used as drugs. <IMAGE>
Patent NO-930200-D0 (NO)
Inventor: UHLMANN EUGEN
IPC: C07H21/04
Filed: 1993-01-21
Abstract: Oligonucleotide analogs (I) and their physiologically tolerable salts. Oligonucleotide analogs and their physiologically tolerable salts of formula (I) are new. R<1> = H, a substituent or -P(=W)ZZ'; R<2> = H, OH, 1-18C alkoxy, halo, azido or amino; B = nucleotide base residue; A = oxy or methylene; d, e, f = 0-50; i = 1-10; r = 0 or 1; W = oxo, selenoxo or thioxo; V = oxy, sulfandiyl or imino; Y = oxy, sulfandiyl, imino or methylene; Y' = oxy, sulfandiyl, imino, (CH2)m or V(CH2)m; m = 1-18; X = OH or SH; U, R<3>, R<4> = substituents; p = 1-100; q = 0-18; R<11> = H or functional group; Sp = a (3',5'-) spacer group of formula (i); g, g' = 0 or 1; h = 0-10; G = 1-12C alkylene (optionally substituted), (6-14C)aryldi-(1-8C)alkylene, 6-18C arylene, (CH2CH2V) alpha CH2CH2, (CH2V) alpha CH2, -(G-Y-P(=W)(U)-Y'-) beta  or a group of formula (ii);  alpha  = 1-11;  beta  = 1-6; Z, Z' = OH, (seleno)thio or a substituent; provided that r is 0 when V is Y' and is 1 if i is greater than 1. Positions of R<2> and the adjacent phosphoryl residue can be reversed; each nucleoside had D- or L-configuration and each B has alpha  or  beta  configuration. Independent claims are also included for: (1) a method for producing (I); (2) the phosphitylation reagent of formula DMTr-X'-G'-Y''-P(U')(NR<5>R<6>); and (3) a pharmaceutical composition containing at least one compound (I) and optionally auxiliary, carrier and/or other active agents. R<5>, R<6> = 1-12C alkyl or together form a 5-6 membered ring; DMTr = dimethoxytrityl; X', Y'' = oxy or sulfandiyl; U' = 1-4C alkyl or protected OH; G' = (CH2CH2O) alpha CH2CH2 or CH2CH(OR')CH2; and R' = 1-18C alkyl, 6-14C aryl or 6-14C aryl(1-8C) alkyl.
Patent NO-930491-D0 (NO)
Inventor: BENIMELI DOMINIQUE
IPC: E21B47/08
Filed: 1993-02-11
Abstract: The invention relates to a logging method and apparatus for investigating the geometrical characteristics of a borehole. The apparatus comprises an array of circumferentially spaced apart azimuthal current electrodes (Aazi) disposed on a sonde (21), and an annular current electrode (A) longitudinally spaced apart from the array of azimuthal electrodes. Currents (Ici) are emitted between the azimuthal electrodes and the annular electrode (A). Monitor electrodes (M, Mazi) are respectively associated with the current electrodes (A, Aazi). The potential differences ( DELTA Vci) between the annular monitor electrode (M) and each of the azimuthal monitor electrodes (Mazi) are detected. In response to the detected potential differences, output signals (Rci) are generated indicative of the distances between the sonde and the wall of the borehole in a plurality of directions around the sonde. The invention also relates to the application of such a technique to azimuthal resistivity measurements of earth formations for correcting said measurements for sonde eccentring and/or for the irregular shape of the section of the borehole. <IMAGE>
Patent NO-940218-D0 (NO)
Inventor: RAYCHAUDHURI SYAMAL
IPC: A61K39/39
Filed: 1994-01-21
Abstract: A compsn. is new, and comprises an antigen (I), except an albumin, mixed with an antigen formulation (II) consisting of: a stabilising detergent; a micelle-forming agent; and a biodegradable and biocompatible oil. (II) is a stable oil-in-water emulsion. Also new is a method for inducing a cytotoxic T-lymphocyte response in a human or animal comprising administering (I) and (II), (II) lacking an immunostimulating peptide component. (I) may be antigenic portions of HIV gp120, malaria antigens, CS protein and Sprorozoite surface protein, influenza antigens, carcinoma P21, etc. (I) also may not include a B-cell lymphoma anitgen.
Patent NO-940306-D0 (NO)
Inventor: BIETTI GIUSEPPE
IPC: A61K31/495
Filed: 1994-01-28
Abstract: Pharmacologically active benzimidazolone derivatives as 5-HT1A and 5-HT2 receptors, useful in the treatment of CNS disorders of formula:   <CHEM>  wherein R1 and R2 may be at the same time or not a hydrogen atom, halogen, trifluoromethyl, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 acyl, carboxyl, C1-6 alkoxy- carbonyl, hydroxy, nitro, amino optionally C1-4 alkyl N-mono or di-substituted, C1-6 acylamino, C1-6 alkoxycarbonylamino, carbamoyl optionally C1-4 alkyl N-mono or di-substituted, cyano, C1-6 alkylsulphinyl, C1-6 alkylsulphonyl, amino sulphonyl optionally C1-4 alkyl N-mono or di-substituted, C1-4 alkyl N-mono or di-substituted aminosulphonylamino, aminosulphonylamino;     R3 is hydrogen, C1-6 alkyl, C2-6 alkenyl or C2-C6 alkynyl;     A is -CO- or -CONH- or it is absent;     B is a straight or branched, saturated or unsaturated C2-6 alkyl;     m and n are both independently an integer from 1 to 3; R4 is an aryl, aralkyl, a heteroaryl or heteroaralkyl group, each group being optionally substituted by one or more substituents selected from halogen, trifluoromethyl, cyano, C1-3 alkoxy, C1-4 alkyland acid addition salts thereof. The process for the preparation of the compounds of formula I as well as pharmaceutical compositions containing them are also described.
Patent NO-944306-D0 (NO)
Inventor: DANELL DAG ERIK
IPC: H05B47/12
Filed: 1994-11-11
Abstract: The invention relates to an arrangement for activating one or more light-generating device (2) belonging to a defined space (1) in a contactless fashion when a first person enters the defined space, and to deactivate the light-generating device (2) when the first person, or a last person, leaves the space. The arrangement includes a sound-wave receiving means (5) which when detecting sound waves that lie within a predetermined first frequency band initiates activation of the light-generating device (2) and which initiates deactivation of the light-generating device (2) when no sound waves that lie within the frequency band are detected. The sound-wave receiving means is constructed to detect sound waves of extremely low frequency within a predetermined narrow frequency band (0-5 Hz) and/or variations in air pressure.
Patent NO-945024-D0 (NO)
Inventor: LINDEBERG JAN-INGE
IPC: C04B41/50
Filed: 1994-12-23
Abstract: PCT No. PCT/SE93/00487 Sec. 371 Date Dec. 14, 1994 Sec. 102(e) Date Dec. 14, 1994 PCT Filed Jun. 2, 1993 PCT Pub. No. WO94/00651 PCT Pub. Date Jan. 6, 1994The present invention relates to a stone product in sheet form suitable for use both outdoors and indoors, e.g. as a facade cladding or a fitting, etc. The stone product in question has undergone impregnation treatment with a view to causing its strength and flexibility to be increased through the presence of an impregnating agent in existing pores, cracks and other cavities in the stone sheet in question. A method for producing said stone product and means for its manufacture are also included in the invention.
Patent NO-952611-D0 (NO)
Inventor: SOMERS LOWELL M
IPC: A61P25/02
Filed: 1995-06-29
Abstract: The present invention relates to a novel class of benzoylecgonine, ecgonine and ecgonidine derivatives which are useful for preventing and treating immunoregulatory disorders, neuromuscular disorders, joint disorders, connective tissue disorders, circulatory disorders and pain. The compounds of this invention are conveniently obtained by chemical synthesis. Accordingly, this invention also relates to methods for preparing the benzoylecgonine, ecgonine and ecgonidine derivatives and to pharmaceutical compositions containing these derivatives.
Patent NO-952835-D0 (NO)
Inventor: WELCH M BRUCE
IPC: C07C51/31
Filed: 1995-07-17
Abstract: A catalyst system comprising a bridged fluorenyl-containing metallocene, an unbridged metallocene, and a suitable cocatalyst and the use of such catalyst systems to produce olefin polymers. Also novel olefin polymers produced by those processes.
Patent NO-953758-D0 (NO)
Inventor: HOLIGHAUS ROLF
IPC: C10B53/07
Filed: 1995-09-22
Abstract: PCT No. PCT/EP94/00954 Sec. 371 Date Dec. 27, 1995 Sec. 102(e) Date Dec. 27, 1995 PCT Filed Mar. 25, 1994 PCT Pub. No. WO94/22979 PCT Pub. Date Oct. 13, 1994A process is disclosed for processing used or waste plastic materials in order to recover chemical raw materials and liquid fuel components by depolymerisation of the used materials, which are transformed into a pumpable and into a volatile phase. The volatile phase is separated into a gaseous phase and a condensate or condensable depolymerisation product, which are refined by standard usual procedures. The pumpable phase remaining once the volatile phase is separated is subjected to liquid phase hydrogenation, gasification, low temperature carbonisation or to a combination of said processes.
Patent NO-960334-D0 (NO)
Inventor: EDENBAUM MARTIN
IPC: D04B21/18
Filed: 1996-01-26
Abstract: A warp-knit casting bandage fabric is provided which comprises a first group of a plurality of individual continuous multifilament fiberglass yarns which form lengthwise extending chains of spaced-apart loops and a second group of a plurality of individual continuous multifilament fiberglass yarns which are separately interspersed with a plurality of individual continuous thermoplastic yarns forming a widthwise extending and lengthwise spaced-apart inlay which is interlaced with the spaced-apart loops forming an open-knit construction wherein the continuous thermoplastic yarns comprise from about 50% to about 100% of the total number of individual yarns forming the inlay. An elongated, resin-impregnated bandage, having a leading edge and a trailing edge, made from the warp-knit casting bandage fabric is also provided as well as a method for forming such resin-impregnated bandages.
Patent NO-972623-D0 (NO)
Inventor: HISKETT SIMON PHILIP
IPC: A61P25/08
Filed: 1997-06-06
Abstract: PCT No. PCT/GB95/02865 Sec. 371 Date Jun. 26, 1997 Sec. 102(e) Date Jun. 26, 1997 PCT Filed Dec. 7, 1995 PCT Pub. No. WO96/17611 PCT Pub. Date Jun. 13, 1996The present invention relates to a pharmaceutical formulation of lamotrigine, pharmaceutically acceptable salts thereof and the preparation of such a formulation.
Patent NO-974502-D0 (NO)
Inventor: CHEEVER MARTIN A
IPC: A61K38/08
Filed: 1997-09-29
Abstract: Compounds and compositions for eliciting or enhancing immune reactivity to HER-2/neu protein are disclosed. The compounds include polypeptides and nucleic acid molecules encoding such peptides. The compounds may be used for the prevention or treatment of malignancies in which the HER-2/neu oncogene is associated.
Patent NO-980858-D0 (NO)
Inventor: GOODMAN MICHAEL
IPC: B65D83/14
Filed: 1998-02-27
Abstract: A device for providing pharmaceutical doses comprising a container, filled with a pharmaceutical composition including glyceryl trinitrate and 1,1,1,2-tetrafluoroethane (HFC-134a) or 1,1,1,2,3,3,3-heptafluoropropane (HFC-227) as a propellant, and valve means arranged for delivering aerosol doses of said pharmaceutical composition to the exterior of the container, wherein at least a portion of the device is formed from a polyester. Compositions for use in such devices are also described.
Patent NO-981042-D0 (NO)
Inventor: BROWN STEPHEN
IPC: A61K31/53
Filed: 1998-03-10
Abstract: Disclosed are anticancer tumor soft gelatin capsules comprising a 1,2,4-benzotriazine oxide and an oily excipient selected from the group consisting of soybean oil and fractionated coconut oil.
Patent NO-981352-D0 (NO)
Inventor: ERDELMEIER CLEMENS
IPC: A61K36/18
Filed: 1998-03-25
Abstract: Disclosed is an improved extract of Hypericum perforatum L. (St. John's wort) containing Hyperforin, in which the Hyperforin is stabilized against decomposition or degradation by means of a stabilizer.
Patent NO-994925-D0 (NO)
Inventor: KNUTZON DEBORAH
IPC: A23K1/16
Filed: 1999-10-08
Abstract: The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to γ-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
Patent GB-0110731-D0 (GB)
Title: Apparatus and method
IPC: E21B21/01
Filed: 2001-05-02
Abstract: Apparatus and method for treating contaminated waste products, such as drill cuttings. The waste products are heated in a reactor vessel so that liquid contaminants evaporate, leaving solids that are safe for disposal.
Patent GB-0122258-D0 (GB)
Title: Vibratory gyroscopic rate sensor
IPC: G01C19/5684
Filed: 2001-09-14
Abstract: A single axis rate sensor including a substantially planar vibratory resonator (1) having a substantially ring or hoop-like structure with inner and outer peripheries (1a, 1b) extending around a common axis (z) drive means (6) for causing the resonator (1) to vibrate in a Cos 2theta vibration mode, carrier mode pick-off means (7) for sensing movement of the resonator (1) in response to said drive means pick-off means (9) for detecting Sin 2theta vibration mode motion induced by rotation around the Z-axis, Sin 2theta vibration mode drive means (8) for nulling said motion and support means (2) for flexibly supporting the resonator (1) and for allowing the resonator (1) to vibrate relative to the support means (2) in response to the drive means, or to applied rotation wherein the support means comprises only L support beams, where L<>2<K>, and K=0, 1,2 or 3.