baber/WOPTO huggingface dataset:
Patent AU-2022336160-B2 (AU)
Title: Potency assay for therapeutic potential of coding nucleic acid
Inventor: HAAS HEINRICH
IPC: C12N15/67
Filed: 2022-09-01
Granted: 2023-10-19
Abstract: The invention provides potency assays for measuring, determining, identifying, quantifying, confirming, and/or validating the therapeutic potential of nucleic acid such as RNA encoding a pharmaceutically active peptide or polypeptide. The potency assays may be performed with nucleic acid such as RNA encoding various types of peptides or polypeptides, including pharmaceutically active peptides or polypeptides comprising one or more antigens or one or more epitopes. Nucleic acid such as RNA having therapeutic potential may be useful in downstream clinical applications, e.g., for eliciting an immune response against one or more antigens or one or more epitopes encoded by the nucleic acid in a subject which immune response may be therapeutic or partially or fully protective. Thus, the nucleic having therapeutic potential may be useful for vaccination.
Patent JP-4106581-B2 (JP)
IPC: E21D11/08
Filed: 1998-11-26
Granted: 2008-06-25
Abstract: A device for supporting two constructional elements against each other consisting of at least one upset tube arranged between pressure transmitting plates located at the ends of the tube for the purpose of limiting inward and outward bulging. The upset tube is coaxially arranged between two supporting tubes having a smaller length than the upset tube of which the external supporting tube encloses the upset tube at a radial distance.
Patent JP-3694652-B2 (JP)
IPC: B41J2/055
Filed: 1999-03-10
Granted: 2005-09-14
Abstract: A method of polarizing a portion of a monolithic piezoelectric actuator element for use in droplet deposition apparatus where the element has first and second portions, includes the steps of placing the first portion of the element at an equipotential and generating a polarizing electric field across the second portion between said first portion and a further conducting layer.
Patent JP-3997055-B2 (JP)
IPC: B30B3/04
Filed: 1999-07-19
Granted: 2007-10-24
Abstract: The present invention concerns a compacting machine, in which the compacting elements can be removed from the compactor housing transversely to the direction of the drive shafts.
Patent JP-4779203-B2 (JP)
IPC: A23L13/20
Filed: 1999-08-27
Granted: 2011-09-28
Abstract: This invention provides a method for separating and extracting biological products of avian origin. The method allows for the production of avian cartilages and of active ingredients which can be extracted from the cartilages thus obtained.
Patent JP-4463421-B2 (JP)
IPC: G10L21/00
Filed: 1999-09-23
Granted: 2010-05-19
Abstract: The invention concerns a music generating method which consists in: an operation defining musical moments during which at least four notes are capable of being played, for example, bars or half-bars; an operation defining two families of note pitches, for each musical moment, the second family of note pitches having at least one note pitch which does not belong to the first family; an operation forming at least a succession of notes having at least two notes, each succession of notes being called a musical phrase, succession wherein, for each moment, each note whereof the pitch belongs exclusively to the second family is exclusively surrounded with notes of the first family; and an operation producing the output of a signal representing each pitch of each succession of notes.
Patent JP-4294874-B2 (JP)
IPC: C07C303/16
Filed: 1999-11-22
Granted: 2009-07-15
Abstract: The invention relates to a process for the prepartaion of alkanesulfonic acids, comprising the following steps:(a) oxidation of alkylmercaptans and/or dialkyl disulfides and/or dialkyl polysulfides having from three to nine sulfur atoms with nitric acid to form alkanesulfonic acids, water, nitrogen oxides and other byproducts,(b) regeneration of the nitrogen oxides obtained from step (a) with oxygen to give nitric acid and recycling of the nitric acid to step (a),where steps (a) and (b) are carried out in reaction chambers separate from one another.
Patent JP-5198695-B2 (JP)
IPC: H04N7/173
Filed: 2000-01-14
Granted: 2013-05-15
Abstract: Disclosed are a method, apparatus and system for providing action selections to an image referencing a product in a video production and a content reference architecture beneficially used therewith. According to the disclosure a method for providing action selections to an image referencing a product in a video production includes (1) communicating a video production to a reproducing apparatus, the video production comprising a placement zone and a trigger zone at least partially coincident with the placement zone, wherein the trigger zone comprises a trigger resource identifier, and wherein the placement zone comprises an image referencing a product; (2) communicating to the reproducing apparatus an indication that an action selection interface associated with the product is available in response to a request corresponding to the trigger; and (3) communicating to the reproducing apparatus a characterization of the action selection interface, wherein the action selection interface comprises a selectable action. A disclosed method includes receiving a first request (URI) from a reproducing apparatus, for example a set-top box, the first request having been extracted from a video production communicated to the reproducing apparatus; determining a second resource identifier (URL) responsive to the first request and redirecting the first request wherein a response is provided to the reproducing apparatus.
Patent JP-5209832-B2 (JP)
IPC: A61K31/341
Filed: 2000-04-05
Granted: 2013-06-12
Abstract: Derivatives of aryl and heterocyclic ureido and aryl and heterocyclic carboxamido phenoxy isobutyric acids have been found to inhibit the nonenzymatic glycation of proteins which often results in formation of advanced glycation endproducts and crosslinks. Many other phenoxyisobutyric acid derivatives as well as certain other compounds as set out in this disclosure also have been found to inhibit the nonenzymatic glycation of proteins. The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood and in the intracellular environment such as occurs with diabetes. The structural and functional integrity of the affected molecules become perturbed by these modifications and can result in severe consequences. The compounds of the present invention can be used to inhibit this process of nonenzymatic glycation and therefore to inhibit some of the ill effects caused by diabetes or by aging. The compounds are also useful for preventing premature aging, spoilage of proteins in food and can prevent discoloration of teeth.
Patent JP-4488146-B2 (JP)
IPC: B60S1/40
Filed: 2000-05-05
Granted: 2010-06-23
Abstract: A wiper apparatus for motor vehicle windshields is proposed, said apparatus being provided with a driven wiper arm located on the motor vehicle body and movable between reversing positions, on whose free end is fixed one side of a joint pin whose axis extends transverse to the longitudinal axis of the wiper arm and essentially in the direction of movement of the wiper arm. On the joint pin is lodged a wiper blade capable of swinging about the joint axis, the wiper apparatus having means for securing the wiper blade on the joint pin. A particularly cost-effective wiper apparatus is obtained when the securing means for the wiper blade are disposed on the wiper arm and on the side of the wiper blade facing away from said arm cooperate with a stop located on the wiper blade side.
Patent JP-3653006-B2 (JP)
IPC: C01B21/083
Filed: 2001-05-08
Granted: 2005-05-25
Abstract: The process recovers NF3 from a multicomponent fluid containing NF3, one or more components less volatile than NF3, and one or more components more volatile than NF3. The process uses a first distillation column and a second distillation column, each distillation column having a top and a bottom. The process includes the following steps: feeding the multicomponent fluid to the first distillation column at a first feed location below the top of the first distillation column; feeding a cryogenic liquid to the first or second distillation column adjacent the top of the first or second distillation column; withdrawing a mixture containing NF3 from the first distillation column; feeding the mixture to the second distillation column at a second feed location; separating NF3 from the mixture in the second distillation column; and removing a stream of NF3 from the second distillation column.
Patent JP-3645196-B2 (JP)
IPC: G06T19/00
Filed: 2001-06-08
Granted: 2005-05-11
Abstract: There is disclosed a picture synthesizing apparatus for superimposing an auxiliary image upon an image converted as if the image were photographed with a virtual viewpoint, displaying the image in a monitor, and providing the image such that an approach to a surrounding solid object can easily be predicted from the monitor image. The picture synthesizing apparatus includes: an image pickup unit 101 disposed in a car; a viewpoint change image synthesizing unit 102 for changing a viewpoint of the image obtained by the image pickup unit 101 and synthesizing the image; a car straight locus line generation unit 103 for generating a locus line at an arbitrary height of the car, when the car linearly advances; and a car locus line drawing unit 104 for drawing the locus line generated by the car straight locus line generation unit 103 on the image synthesized by the viewpoint change image synthesizing unit 102. <IMAGE>
Patent JP-4006198-B2 (JP)
IPC: G06K15/10
Filed: 2001-06-25
Granted: 2007-11-14
Abstract: An ink jet recording apparatus for effecting recording on a recording material by ejecting a plurality of inks with relative scanning movement between a recording head and the recording material, the ink jet recording apparatus, includes obtaining means for obtaining relative information indicative of a relative relation between the amounts of inks to be ejected for each of unit areas provided by dividing an area in the neighborhood of a boundary between adjacent bands of scanning recording of the recording head on the recording material; determining means for determining, for each of the inks, a reduction rate at which the amount of the ink to be ejected to the neighborhood of the boundary in the unit area on the basis of the relative information for each of the unit areas obtained by the obtaining means and on the basis of quantity information indicative of an amount of each ink to be ejected in the unit area; and reducing means for reducing the amount of each ink to be ejected to the neighborhood of the boundary on the basis of the reduction rate for each ink determined by the determining means. <IMAGE>
Patent JP-3699992-B2 (JP)
IPC: C04B35/565
Filed: 2001-08-20
Granted: 2005-09-28
Abstract: The present invention provides a silicon carbide-based heat-resistant, ultra-lightweight, porous structural material having the same shape as that of a spongy porous body and also provides a process for readily producing the material. <??>In the process of the present invention, slurry containing silicon powder and a resin is applied to the framework of the spongy porous body by an impregnation method in such a manner that interconnected pores of the porous body are not plugged with the slurry; the resulting porous body is carbonized at a temperature of 900 DEG C to 1320 DEG C in vacuum or in an inert atmosphere; the resulting porous body is subjected to reactive sintering at a temperature of 1320 DEG C or more in vacuum or in an inert atmosphere, whereby silicon carbide having high wettability to molten silicon is produced and open pores due to a volume reduction reaction are formed in one step; and molten silicon is infiltrated into the resulting porous body at a temperature of 1300 DEG C to 1800 DEG C in vacuum or in an inert atmosphere, whereby the silicon carbide-based heat-resistant, ultra-lightweight, porous structural material is produced.
Patent JP-3703432-B2 (JP)
IPC: F16L21/06
Filed: 1999-12-14
Granted: 2005-10-05
Abstract: A band clamp for pipe joints is disclosed comprising a band with confronting sidewalls when wrapped around pipes to be coupled. The clamping mechanism includes a pair of force bars outboard of the sidewalls and a spline with concave surfaces on opposite sides, the spline being disposed between the end flanges. A bolt extends through bolt holes and draws the flanges against the spline to stretch the band around the pipes when the bolt is tightened against the force bars. The sidewalls have lateral flanges which overhang the spline to arrest movement of the sidewalls relative to the spline to obtain alignment of the bolt holes when the clamp is tightened. In some embodiments, the band is folded back on itself to form a double thickness which extends from the upper end of each sidewall to a point beyond the lower end of the sidewall and provides an inverted flap sandwiched between the clamp band and the pipe. The inverted flap may be secured to the band by mechanical interlock between the layers.
Patent JP-4643095-B2 (JP)
IPC: C09J175/06
Filed: 2000-06-20
Granted: 2011-03-02
Abstract: This invention relates to binders for aqueous coatings, to a process for the production thereof and to the use thereof for lacquers and coatings.
Patent JP-5102925-B2 (JP)
IPC: C07D491/18
Filed: 2001-02-09
Granted: 2012-12-19
Abstract: An efficient process is described for the synthesis of 5, a key intermediate for the synthesis of the potent antitumor agents ecteinascidin 743 (1) and phthalascidin (2) from the readily available building blocks 3b and 4.
Patent JP-4799794-B2 (JP)
IPC: C07C231/12
Filed: 2001-03-21
Granted: 2011-10-26
Abstract: The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide delivery agent compounds for the delivery of active agents. Methods of administration are provided as well.
Patent JP-4865976-B2 (JP)
IPC: C21C5/28
Filed: 2001-05-22
Granted: 2012-02-01
Abstract: A treatment method includes injecting oxygen into the liquid steel works slag, adding and dissolving in the slag alumina and lime sources, and optionally silica and iron sources and cooling the slag until solidification, the additions being carried out in such amounts and the cooling being performed at such speed that the resulting slag has a mineralogical composition having one of the following constituting element: (a) an amorphous glassy phase; (b) a first group of phases (1) consisting, in weight percentages, of 10-40 CA, 20-50 C2AS, 30-50 C6AF2 and 10-30 C2S; (c) a second group of phases (2) consisting, in weight percentages, of 20-40 C2F, 10-30 C2AS, 20-50 C6AF2 and 10-40 C2S, and (d) a mixture of amorphous glassy phase and of the first or second group of phases. The invention is applicable to hydraulic binders.
Patent JP-4032758-B2 (JP)
IPC: G08C13/00
Filed: 2002-01-24
Granted: 2008-01-16
Abstract: <P>PROBLEM TO BE SOLVED: To implement highly accurate trimming on sensor output by a simple constitution in a sensor apparatus.  <P>SOLUTION: The sensor apparatus is provide with a sensor signal processing IC 26, and the sensor signal processing IC 26 is provided with sensor elements 22 and 24 for outputting analog voltages corresponding to physical quantities, a temperature change detecting circuit 32 for outputting a voltage corresponding to a change in temperature, and secondary ΔΣ modulators 44-48 for ΔΣ- converting analog output of the sensor elements 22 and 24 and analog output of the temperature change detecting circuit 32 each into over-sampling 1-bit digital signals. The sensor apparatus is provided with a microcomputer 70 for performing digital filter processing on each output of the ΔΣ modulators 44-48 and then trimming each output of the sensor elements 22 and 24 according to output data of the sensor elements 22 and 24, output data of the temperature change detecting circuit 32, and data stored in a compensation amount data memory 84 and indicating the temperature characteristics of the sensor elements 22 and 24.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-4001009-B2 (JP)
IPC: G02F1/1333
Filed: 2002-12-20
Granted: 2007-10-31
Abstract: <P>PROBLEM TO BE SOLVED: To provide a transflective liquid crystal display capable of obtaining light and high-contract display having a wide viewing angle.  <P>SOLUTION: This liquid crystal display employs a vertical alignment mode using a liquid crystal layer 50 that is vertically aligned in the initial alignment state, wherein a transparent display area T is disposed to surround the periphery of a reflective display area R in one dot. An insulating film 21 is provided in the area that corresponds to the reflective display area R in the center of the dot, the insulating film 21 making the thickness of the liquid crystal layer 50 in the reflective display area R smaller than the thickness of the liquid crystal display area 50 in the transparent display area T.  <P>COPYRIGHT: (C)2004,JPO
Patent JP-5341292-B2 (JP)
IPC: B22D7/00
Filed: 2001-05-21
Granted: 2013-11-13
Abstract: High purity niobium metals and alloys containing the same are described. The niobium metal preferably has a purity of at least 99.99% and more preferably at least 99.999%. In addition, niobium metal and alloys thereof are described, which either have a grain size of about 150 microns or less, or a texture in which a (100) intensity within any 5% increment of thickness is less than about 30 random, or an incremental log ratio of (111):(100) intensity of greater than about -4.0, or any combination of these properties. Also described are articles and components made from the niobium metal which include, but are not limited to, sputtering targets, capacitor cans, resistive film layers, wire, and the like. Also disclosed is a process for making the high purity niobium metal which includes the step of reacting a salt-containing niobium and a metal salt along with at least one compound capable of reducing the salt-containing niobium to niobium and in a reaction container. The reaction container or liner in the reaction container and the agitator or liner on the agitator are made from a metal material having the same or higher vapor pressure of melted niobium. The high purity niobium product preferably has a fine and uniform microstructure.
Patent JP-4949601-B2 (JP)
IPC: A61C13/30
Filed: 2001-09-14
Granted: 2012-06-13
Abstract: The taper (2) where the threaded section of the implant (1) begins and the position of the straight cutting edge of the apical end (3) can be adjusted, thus making the thread more effective and improving the initial implant position. The holder casing (7) incorporates a hexagonal abutment (8, 9) and the shaft incorporates an O-ring seal (14). <IMAGE>
Patent JP-3943495-B2 (JP)
IPC: H04W88/18
Filed: 2001-11-16
Granted: 2007-07-11
Abstract: A method of transmitting messages in a telecommunication system includes a first network offering circuit-switched services, a second network offering packet-switched services, and at least one mobile station supporting the first and the second network. When the need arises to transmit at least one message, a check is made to see if the mobile station is attached to the second network. The message is transmitted to the second network if the mobile station is attached to the second network. The message is transmitted to the first network in case of a failure to transmit the message via the second network.
Patent JP-4317364-B2 (JP)
IPC: A01N25/10
Filed: 2001-12-11
Granted: 2009-08-19
Abstract: An improved termite bait composition comprises a powdered cellulosic attractant having a particle size in the range of approximately 1 to 100 micrometers and a termite killing agent. Also disclosed are a method for controlling termites by applying the termite bait composition to a termite infested area and a termite bait composition package for use in a termite bait station comprising the termite bait composition contained within a termite attractive package.
Patent JP-4487548-B2 (JP)
IPC: H05B41/14
Filed: 2003-12-08
Granted: 2010-06-23
Abstract: <P>PROBLEM TO BE SOLVED: To surely carry out checkout even in a place where an instantaneous power fault tends to take place or in a place allowing a checking switch to be easily pushed, in a lighting system for lighting a lamp by a secondary battery in a power fault.  <P>SOLUTION: This lighting system comprises: a lighting means for lighting the lamp 2 by power supply from the secondary battery 1 in a power fault; a checking means for forcibly lighting the lamp 2 over a predetermined checking time by the lighting means to check the secondary battery 1; a monitoring means for always monitoring a plurality of operation states including a charge state of the secondary battery 1; and a counting means for counting at least one of a charge time and a discharge time of the secondary battery 1. The lighting system is so structured that, when a power fault occurs while the counting means is counting the charge time, the counting means continues the charge time count after the recovery of power from the state immediately before the power fault occurrence without initializing the count value if the power fault is ended in a short time.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-4317007-B2 (JP)
IPC: C07C323/20
Filed: 2002-03-06
Granted: 2009-08-19
Abstract: An organoaluminum reaction product of A.) a ligand of the formula I, wherein R1 represents an alkyl, aryl, arylalkyl, or alkylaryl group, a C3-24 silyl group, or hydrogen, R2, R3, R4, R5, R6, R7, R12, and R13 are the same or different and represent an alkyl, aryl, arylalkyl, or alkylaryl group, a C3-24 silyl group, halide, or hydrogen, with the proviso that at least one of the groups R4 and R13 represents hydrogen, R8 represents an alkoxy, alkyl, aryl, arylalkyl, or alkylaryl group, a C3-24 silyl group, halide, hydroxyl radical, or hydrogen, E represents O, S, Se, or Te, and n is an integer from 1 to 4, and B.) an aluminum compound of formula A1R9R10R11, wherein R9 and R10 are the same or different and represent C1-20 alkyl, aryl, arylalkyl, or alkylaryl group, or hydrogen, and R11 is a C1-20 alkyl, aryl, arylalkyl, alkylaryl or alkoxy group, hydrogen, or halogen is useful as a polymerization catalyst, particularly for the homopolymerization or copolymerization of an alkylene oxide.
Patent JP-4136935-B2 (JP)
IPC: F02M31/20
Filed: 2002-10-22
Granted: 2008-08-20
Abstract: The invention relates to a fuel injection system for a diesel engine cooled by a cooling water circuit comprising a storage tank, a distribution system, an injection harness and a draining circuit. The distribution system comprises a pump and a device for the selective heating of the fresh fuel flow before admission into the pump, and the injection harness injects part of the fuel into the engine. The draining circuit comprises a device for cooling the flow of non-injected fuel, and is used for the selective return of the flow toward the storage tank. The selective heating device comprises a recycle line and a direction setting element which can be used selectively to recycle the flow of non-injected fuel upstream of the pump.
Patent JP-4554241-B2 (JP)
IPC: G06F9/44
Filed: 2004-03-16
Granted: 2010-09-29
Abstract: A method of performing cache coloring includes the steps of generating function strength information in response to a dynamic function flow representing a sequence in which a plurality of functions are called at a time of executing a program comprised of the plurality of functions, the function strength information including information about runtime relationships between any given one of a plurality of functions and all the other ones of the plurality of functions in terms of a way the plurality of functions are called, and allocating the plurality of functions to memory space in response to the function strength information such as to reduce instruction cache conflict.