baber/WOPTO huggingface dataset:
Patent EP-1450605-A2 (EP)
Inventor: DRAGHIA-AKLI RUXANDRA
IPC: C07K14/60
Filed: 2002-10-25
Abstract: Cette invention concerne une méthode permettant de réduire le taux d'adiposité, d'augmenter la masse maigre, d'augmenter la densité osseuse ou d'accroître la vitesse de guérison osseuse d'un sujet. D'une manière générale, les modes de réalisation de cette invention peuvent être mis en oeuvre selon une méthode consistant à introduire une séquence d'acide nucléique hétérologue codant la GHRH (hormone de libération de l'hormone de croissance) ou un équivalent biologique fonctionnel de cette hormone dans les cellules du sujet, puis à permettre à l'expression du gène codé de se produire alors que les cellules modifiées se trouvent dans le sujet. Par exemple, lorsqu'une séquence d'acide nucléique de ce type est introduite dans les cellules spécifiques des tissus du sujet, on obtient une expression constitutive spécifique. En outre, une régulation externe du gène de la GHRH ou de son équivalent biologique fonctionnel peut être effectuée au moyen de promoteurs inductibles régulés par des molécules à séquence activatrice administrées au sujet. La méthode préférée de la présente invention consiste à introduire les séquences de codage d'acide nucléique inductibles ou constitutives de la GHRH ou de ses équivalents biologiques fonctionnels directement dans les cellules du sujet selon un procédé d'électroporation in vivo. Une réduction du taux d'adiposité et une augmentation de la masse maigre chez un sujet peuvent être obtenues au moyen de l'introduction chez le sujet de GHRH ou de son équivalent biologique fonctionnel selon le procédé ci-décrit comme protéines de recombinaison. Cette invention permet également d'obtenir une augmentation de la densité osseuse et un accroissement de la vitesse de guérison osseuse.
Patent EP-1418985-A2 (EP)
Inventor: MCDONALD THOMAS K
IPC: A42B3/22
Filed: 2002-05-31
Abstract: L'invention concerne un casque radio multiphase (50) destiné aux membres de l'équipage d'un aéronef. Ce casque radio comprend un masque à gaz gonflable (54) et une visière (56) venant se fixer sur la tête d'un utilisateur (60) au moyen d'une structure de montage (52). Le casque (50), dans son ensemble, comprend également une structure de commande (60) mobile pouvant être utilisée de façon sélective et/ou automatique. La structure de montage (52) comprend avantageusement une paire de cache-oreilles (62, 64) et une sangle (66) permettant de positionner le casque (50) sur la tête de l'utilisateur, le masque et la visière (54, 56) étant situés à proximité du sommet de la tête de l'utilisateur. En cas de danger, le masque (54) est abaissé et le corps du masque (124) est gonflé pour fournir un gaz respirable à l'utilisateur (60). La visière (56) peut également être abaissée pour être placée sur le masque (54). La structure de commande (60) mobile pouvant être activée par voie pneumatique ou électrique permet de faire passer le masque et la visière (54, 56) d'une position rétractée à une position déployée. Pour éviter que la fumée ne pénètre dans le masque, des joints physiques ou des rideaux d'air (144, 286) peuvent être disposés le long des bords supérieurs et inférieurs de la visière et du masque (56, 54).
Patent EP-1461070-A2 (EP)
Inventor: KNUDSEN LOTTE BJERRE
IPC: A61P43/00
Filed: 2002-12-20
Abstract: Methods and uses for treatment of diabetic late complications comprising administration of a GLP-1 compound and a modulator of diabetic complications.
Patent EP-1458889-A2 (EP)
Inventor: VAN EIJK MICHAEL JOSEPHUS THER
IPC: C12Q1/68
Filed: 2002-12-30
Abstract: A method for determining the presence or absence of at least one target sequence in a nucleic acid sample, comprising the steps of performing an oligonucleotide ligation assay, digesting the resulting amplified probes with a restriction enzyme isolating detectable fragments and the determining the presence of detectable fragments by mass spectrometry.
Patent EP-1436762-A2 (EP)
Inventor: BLOOMBERG BENTLEY
IPC: B42D15/10
Filed: 2002-10-02
Abstract: A security material for documents comprises a first layer of material, such as a polymeric film or laminate, having first and second sides. A pearlescent material is applied to at least one of the first and second sides. The pearlescent material defines a pattern comprising at least two different colors that are at least partially interlocked in the pattern, and the pattern permits printed information that is overlaid by the pattern to be effectively perceived.
Patent EP-1430305-A2 (EP)
Inventor: HAVRANOVA MARIE
IPC: G01N33/577
Filed: 2002-09-10
Abstract: Procédé de mesure de l'activation des basophiles consécutive à une stimulation par un allergène en vue de déterminer une hypersensibilité à certaines substances. Le procédé comporte les étapes consistant à : incuber un échantillon de sang auquel a été ajouté de l'interleukine-3 à raison de 0,05 à 50 ng/ml sur la base du volume de l'échantillon, et un allergène dilué de façon appropriée à raison de 0,5 à 100 unités/ml, à une température correspondant au milieu physiologique, pendant 15 à 45 minutes ; ajouter ensuite aux basophiles un anticorps anti-CD63 de coloration, à raison de 3 à 30 νl/100 νl de sang, et un anticorps dirigé contre un récepteur de surface des basophiles à raison de 3 à 30 νl/100 νl de sang, à une température comprise entre 0 et +10 °C ; incuber l'échantillon dans un bain de glace pendant 15 à 30 minutes après l'avoir soumis à un écoulement tourbillonnaire ; lyser ensuite l'échantillon et le soumettre à une cytométrie de flux.
Patent EP-1429746-A2 (EP)
Inventor: BUNICK FRANK J
IPC: A61K9/20
Filed: 2002-09-28
Abstract: A dosage form comprises: (a) at least one active ingredient: (b) a core having a first surface portion upon which resides a first coating and a second surface portion which is substantially free of the first coating; and (c) a shell which resides upon at least a portion of the second surface portion, wherein the shell comprises a different material from the first coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core comprising a center portion having an exterior surface and an annular portion having an exterior surface and an interior surface, wherein the annular portion interior surface is in contact with at least a portion of the center portion exterior surface, and a coating resides on at least a portion of the annular portion exterior surface; and (c) a shell which resides upon at least a portion of the exterior surface of the center portion, wherein the shell comprises a different material than the impermeable coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface and a cavity which extends at least partially through the core such that the core outer surface has at least a first opening therein; (c) a first coating which resides on at least a portion of the core outer surface, wherein the first shell portion comprises a different material from the first coating; and (d) a first shell portion which is adjacent to the first opening and covers at least the first opening.
Patent EP-1442022-A2 (EP)
Inventor: PHILLION DENNIS P
IPC: A61K48/00
Filed: 2002-11-07
Abstract: La présente invention concerne des procédés et des compositions pour réguler l'expression génique de la COX2 dans une cellule. Les procédés consistent à sélectionner une composition polyamide comprenant du N-méthyl pyrrole (Py) et du N-méthyl imidazole (Im), afin de fournir une liaison spécifique à un ADN au niveau d'un site cible du gène de la COX2 dans une cellule. Le polyamide est ensuite combiné avec la cellule contenant le gène de la COX2, il se lie alors au niveau du site promoteur cible du gène de la COX2 et régule la transcription du gène de la COX2.
Patent EP-1532520-A2 (EP)
Title: Fast path for performing data operations
Inventor: TESTARDI RICHARD
IPC: G06F12/1027
Filed: 2002-12-09
Abstract: Described are techniques used in a computer system for handling data operations to storage devices. A switching fabric includes one or more fast path for handling lightweigth, common data operations and at least one control path for handling other data operations. A control path manages one or more fast path. The fast path and the control path are utilized in mapping virtual to physical addesses using mapping table. The mapping tables include an extent table of one or more entries corresponding to varying address ranges. The size of an extent may be changed dynamically in accordance with a corresponding state change of physical storage. The fast path may cache only portions of the extent table as needed in accordance with a caching technique. The fast path may cache a subset of the extent table stored within the control path. A set of primitives may be used in performing data operations. A locking mechanism is described for controlling access to data shared by the control path.
Patent EP-1329539-A2 (EP)
Inventor: WATANABE HIROYUKI
IPC: C03B20/00
Filed: 2003-01-15
Abstract: An object of the invention is to provide a quartz glass crucible for pulling up silicon single
crystal and a method for producing the same, suitable for improving the productivity of the
crucible and the quality of the silicon single crystal, which, by forming a crystalline layer on
the inner surface of the quartz glass crucible during pulling up silicon single crystal, prevents
degradation from occurring on the inner surface of the crucible and increases the ratio of
single crystal while preventing the dislocation from forming on the single crystals. 
     The objects above have been accomplished by a quartz glass crucible, having a double layered
structure comprising a naturally occurring quartz glass outer layer (3) and a synthetic
quartz glass inner layer (4), said synthetic quartz glass inner layer (4) contains at least one
type of an alkali metal ion selected from the group consisting of Na ion, K ion, and Li ion,
which is diffused or moved from said naturally occurring quartz glass outer layer (3) into said
synthetic quartz glass inner layer (4).
Patent EP-1331463-A2 (EP)
Inventor: IWASAKI MITSURU
IPC: B21D53/08
Filed: 2003-01-24
Abstract: In a fin forming step, fins (24,34) of heat exchangers (20,30) are
formed into a connected state where the fins are connected
to each other via a parting portion (50). In a fin attaching
step, the fins (24,34) in the connected state are temporarily
attached to the respective heat exchangers (20,30). In a fin
fixing step, an integrated heat exchanger in which the
fins (24,34) are temporarily attached is passed through a heating
oven to braze the fins (24,34) to the respective heat exchangers (20,30).
In a fin separating step W4, the fins (24,34) in the connected
state of the respective heat exchangers are separated from
each other in the parting portion (50). Therefore, each of the
heat exchangers (20,30) can independently perform a heat
exchanging operation without being affected by heat
conduction from the other heat exchanger via the fins (24,34).
Patent EP-1339074-A2 (EP)
Inventor: TAKEDA TAKAYUKI
IPC: H01B17/32
Filed: 2003-02-24
Abstract: A method for joining a core member and grippers in a polymer insulator
including a core member, an outer sheath comprised of a body and caps, which are
provided around the core member, and the grippers provided on both ends of the core
member, comprising (a) providing the core member with a filler on the outer
circumferential surface thereof or the grippers with a filler on the inner circumferential
surface thereof, (b) inserting the core member into the grippers, and (c) clinching the
grippers to fasten the grippers and the core member.
Patent EP-1323386-A2 (EP)
Inventor: VENDRELY TIM
IPC: A61B17/56
Filed: 1996-02-15
Abstract: A cutting guide for resecting a patient's proximal tibia to receive a tibial prosthesis is
disclosed. The cutting guide comprises an instrument body (76) and mounting means
for attaching the cutting guide to a rod (21) that tracks the patient's intramedullary
canal (12) which enables the surgeon to reference surgical cuts with respect to the
patient's intramedullary canal. The cutting guide also comprises a cutting element
(78) for being driven longitudinally into the proximal tibia during use, and at least
one cutting guide surface (90, 91) for guiding a saw instrument of the surgeon.
Patent EP-1346777-A2 (EP)
Inventor: DUERR THOMAS
IPC: B05B15/555
Filed: 2003-03-14
Abstract: Device for measuring the quantity of a coating material dispensed by an application device comprises a container (1) into which the application device is introduced and for holding the coating material to be dispensed, and a weighing device connected to the container for weighing the coating material held in the container. The container is provided with a cleaning device for removing any coating material adhering to the application device.  An Independent claim is also included for a process for measuring the quantity of a coating material dispensed by an application device. Preferred Features: The container has on its under side an opening (2) which is closed by a flap (3). The application device is a spray.
Patent EP-1321275-A2 (EP)
Inventor: SETA KUNIHITO
IPC: B29K101/12
Filed: 1999-12-20
Abstract: A thermoplastic resin injection molding machine comprises a plasticating unit (B')
for plasticating a thermoplastic resin, an injecting unit (A) connected to the
plasticating unit (B') through a connecting passage (12) to inject the plasticated
resin into a mold, and a buffering unit having a buffering chamber (21) and
receiving the resin plasticated in the plasticating unit (B'). The buffering unit is
contained in the plasticating unit (B') and is located in a longitudinal direction of the
plasticating unit (B').
Patent EP-1349036-A2 (EP)
Inventor: UCHIDA KAORU
IPC: G06F21/12
Filed: 2003-03-25
Abstract: A source program conversion tool 511 substitutes for
an initialization part of constant data to be included in
a source code S1 an initialization part of alternative
constant data converted to be in a situation in which
decryption is difficult by a reversible conversion process,
and generates a source code S2 having a source of an
inversion process for restoring original constant data
from said alternative constant data inserted into a
location before said constant data to which a reference is
made (Fig.1).
Patent EP-1359043-A2 (EP)
Inventor: KRISHNAMOORTHY PK HARIDASS
IPC: B60K15/04
Filed: 2003-04-08
Abstract: A check valve (10) for connection in a fuel tank filler tube. The
valve has a tubular body (12) with a plurality of radially inwardly
extending vanes or ribs (20) in the inlet end about a portion of the
circumference. The ribs are tapered in the flow direction to deflect the
end of a siphoning hose to an offset opening. A valve seat (24) and
poppet (26) with a tapered surface (36) are disposed downstream of the
ribs, clearance apertures (18) are formed in the side of the tubular
body downstream of the valve seat. The tapered surface of the poppet,
upon being opened by insertion of the end of a siphoning hose deflects
the hose outwardly through the clearance apertures to facilitate further
insertion into the tank. The poppet is biased normally closed by a
spring (28).
Patent EP-1359054-A2 (EP)
Inventor: SCHLECHT WERNER P
IPC: B60R5/04
Filed: 2003-04-10
Abstract: The trunk space cover has an access opening which is at least partially closed by a relatively pivoted cover element (8) having a lesser surface area than that of the access opening (9), which is defined by a frame housing (7) in a stiff contour element (6) attached to the end of the flexible roller web providing the trunk space cover. The cover element can pivot to either side of the access opening plane about a horizontal pivot axis (10), with resetting springs biasing it into a neutral position in the access opening plane.
Patent EP-1363208-A2 (EP)
Inventor: FARAHAT AYMAN O
IPC: G06F17/30
Filed: 2003-05-16
Abstract: Systems and methods for determining the authoritativeness of a document
based on textual, non-topical cues. The authoritativeness of a document is determined
by evaluating a set of document content features contained within each document to
determine a set of document content feature values, processing the set of document
content feature values through a trained document textual authority model, and
determining a textual authoritativeness value and/or textual authority class for each
document evaluated using the predictive models included in the trained document
textual authority model. Estimates of a document's textual authoritativeness value
and/or textual authority class can be used to re-rank documents previously retrieved
by a search, to expand and improve document query searches, to provide a more
complete and robust determination of a document's authoritativeness, and to improve
the aggregation of rank-ordered lists with numerically-ordered lists.
Patent EP-1367787-A2 (EP)
Inventor: MIURA HIROYASU
IPC: H04B7/15
Filed: 2003-05-27
Abstract: A network apparatus having a first converting
section (19) which receives first packet signals (YC1,
YC2) of a plurality of channels in a wired network
communication, and respectively converts the first
packet signals into second packet signals (MC1, MC2)
of a plurality of channels in a wireless network
communication, and a second converting section 18 which
receives third packet signals (MC1, MC2) of a plurality
of channels in the wireless network communication from
an external network apparatus, and respectively
converts other packet signals into third packet signals
(YC1, YC2) of a plurality of channels in the wired
network communication to output the same.
Patent EP-1385160-A2 (EP)
Inventor: HIBINO EIKO
IPC: G11B7/243
Filed: 2003-07-21
Abstract: A phase change optical recording medium having a wide recording
power margin and excellent durability to repetitive recording is
disclosed. The medium includes a first protective layer, a recording
layer, an interface layer, a second protective layer, and a reflective
layer, the layers disposed on a transparent substrate, wherein the
interface layer includes a mixture of ZrO 2  and at least one oxide
of an element, excluding zirconium, selected from a group consisting of
elements of period numbers 3 to 6 and group numbers 2 to 14 of the
periodic table of elements. Preferably, the medium further includes
a second interface layer including the mixture of ZrO 2 
between the first protective layer and the recording layer. In another
preferable aspect, the mixture of ZrO 2  is represented by the following
formula:
 [(ZrO 2 ) 100-α  (X) α ] β  (Z) γ  (ZnS) δ   
   wherein "X" represents an oxide selected from MgO, CaO,
Sc 2 O 3 , Y 2 O 3 , and CeO 2 ; "Z" represents an oxide selected from TiO 2 ,
SiO 2 , Al 2 O 3 , MgO, Ta 2 O 5 , and ZnO; "α" is 2-15 mol%; "β" is 40-100
mol%; "γ" is 0-60 mol%; "δ" is 0-60 mol %; and β + γ + δ = 100 mol%.
Patent EP-1386650-A2 (EP)
Inventor: MIDDELHAUFE AXEL
IPC: B01D17/028
Filed: 2003-07-28
Abstract: The sewage separation system, to give a light phase and/or heavy components, has a sewage feed (12) into a coarse separation stage (100). A major portion of the light phase is gathered into a collection vessel (7) using density differences and/or the heavy components are separated in a sludge trap zone (1). The partially-cleaned sewage passes through a fine feed (17) to a fine separation stage (101), where the remaining light phase is coalesced after mechanical dispersion, and then separated out for return to the collection vessel. The collection vessel has a bulb storage shape, open at the bottom. The fine separation stage is wholly encapsulated, and separated from the coarse separation system.
Patent EP-1401068-A2 (EP)
Inventor: STEPHENS EDWARD F IV
IPC: H01S5/024
Filed: 2003-09-17
Abstract: A laser diode package (10) according to the present invention is tolerant of short-circuit
and open-circuit failures. The laser diode package (10) includes a laser diode bar
(12), a forward-biased diode (14), a heat sink (18), and a lid (16) which may have fusible
links (86). The laser diode bar (12) and the forward-biased diode (14) are electrically
connected in parallel between the heat sink (18) and the lid (16). The emitting region of
the laser diode bar (12) is aligned to emit radiation away from the forward-biased diode
(14). Several packages can be stacked together to form a laser diode array (42). The
forward-biased diode (14) allows current to pass through it when an open-circuit failure
has occurred in the corresponding laser diode bar (12), thus preventing an open-circuit
failure from completely disabling the array (42). The fusible links (86), if used on the lid
(16), prevent damaged active regions (90) in a laser diode bar (12) from short-circuiting
and drawing more electrical current than the other active regions (90).
Patent EP-1394722-A2 (EP)
Inventor: DVORKIS PAUL
IPC: G06K7/10
Filed: 1995-10-27
Abstract: A scanner determines whether a target is a bar code symbol and, if so, whether that
symbol is one-dimensional. For two-dimensional symbols, the scanner aligns a
scanning pattern with the symbol and expands the scanning pattern to reach only to
the top and bottom edge of the symbol, not beyond. The scanner also has a
microprocessor-control scanning engine that uses a coil to drive a scanning element
and pick up feed back signals from the scanning element. A pulse-width-modulated
regulator also provides fast and efficient operation for driving the coil. The scanning
engine can also be designed to generate a pattern that precesses across the target,
and a powerful interface to the scanning engine allows decoding and control logic to
work efficiently with and independently of the scan engine.
Patent EP-1362554-A2 (EP)
Inventor: BONUTTI PETER M
IPC: A61B19/00
Filed: 2003-03-18
Abstract: An improved apparatus and method of securing body tissue may be performed
with a robotic mechanism. The robotic mechanism may be utilized to
tension a suture with a predetermined force and urge a suture retainer toward
body tissue with a predetermined force. Ultrasonic vibratory energy may be
transmitted to the suture retainer to effect a gripping of the suture by the suture
retainer. The body tissue may be secured with a staple. Legs of the staple may
be bonded together to secure the staple. The legs of the staple may be bonded
together by transmitting ultrasonic vibratory energy to the legs of the staple. A
tissue positioning assembly may be used to hold the body tissue in a desired
position. Images of the body tissue being secured may be obtained using various
known devices including one or more endoscopes, a fluoroscope, a magnetic
resonance imaging device, and/or other known imaging devices.
Patent EP-1346752-A2 (EP)
Inventor: PELLEGRINO RICHARD C
IPC: A61B18/18
Filed: 2003-03-20
Abstract: A device for therapeutically treating back or leg pain, comprises a probe having a proximal
portion and a distal portion, and first and second treatment sources located in the distal
portion of the probe. The first treatment source is adapted to therapeutically treat a first
tissue site, and the second treatment source is adapted to therapeutically treat a second
different tissue site. The first and second different tissue sites are selected from the group
consisting of a first intervertebral disc, a first vertebra, a first spinal ligament, a first spinal
facet joint capsule, a second intervertebral disc, a second vertebra, a second spinal
ligament, and a second spinal facet joint capsule.