baber/WOPTO huggingface dataset:
Patent NZ-337056-A (NZ)
Title: A 24 kD protein specific for binding to HCV epitotes which can be used for diagnosis and treatment of HCV related diseases
Inventor: ABRIGNANI SERGIO
IPC: A61K39/29
Filed: 1999-08-04
Abstract: A use of a protein having a molecular weight of 24kD and capable of specifically binding to a protein of hepatitis C virus for treating HCV infection. The method of preparing the protein is characterised by: 1. Culturing plasma cells exhibiting binding to a HCV protein and purifying the protein from the preparation of the cells; 2. The cells are selected and cloned to provide for overexpression of the protein; 3. Subjecting the preparation to ammonium sulphate precipitation to ammonium sulphate at less than 33% saturation and retaining the supernatant; 4. Subjecting the supernatant to an ammonium sulphate precipitation (33 and 50%) purification step and retaining the precipitate; 5. Resuspending the precipitate and subjecting it to hydrophobic interaction chromatography. Figure 1 is a schematic diagram describing an assay in which HCV receptor-binding ligands bind to receptors on HCV receptor target cells and are measured by first binding a labeled anti-rabbit IgG-FITC F(ab') fragment prior to cell separation by FACScan analysis.
Patent NZ-501117-A (NZ)
Title: Air cushion for use in sportswear such as shoes
Inventor: HUANG ING-JING
IPC: A43B7/32
Filed: 1997-06-04
Abstract: Provided is a three-dimensional air cushion (1) having a sealed outer peripheral edge of a geometric shape.  The projected area of the hollow interior (10) sealed by the outer peripheral edge is smaller than the upper surface area of the air cushion.  Air chambers (10) are provided in an upper surface and a lower surface of the cushion, giving excellent buffering function.  Two opposite sides of the cushion have a level higher than an intermediate portion to force an object in protect, or a shock source, to move to the center, with the shock energy converted into side support energy, thus obtaining great stability.  The two opposed lateral sides project above a plane occupied by the base portion to form elevated sidewalls of the air cushion, forming a U-shape with the base portion for distributing shock forces delivered to the sidewalls.
Patent NZ-503829-A (NZ)
Title: 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
Inventor: MARABOUT BENOIT
IPC: A61K31/36
Filed: 1998-10-07
Abstract: Compounds of general formula (I) in which: U represents a group of general formula (A) or (B) in which V represents a hydrogen or halogen atom, a (C1-C3) alkyl group or one or two (C1-C3) alkoxy groups, W and X each represent, respectively, either two oxygen atoms, or an oxygen atom and a CH2 group, or a CH2 group and an oxygen atom, or an oxygen atom and a CO group, n represents the number 0 or 1, and R represents either a propyl group when U represents a 2,3-dihydro-1H-inden-2-yl group of general formula (A), or a hydrogen atom or a (C1-C3) alkyl group when U represents a group of general formula (B), and  Y represents one or more atoms or groups chosen from the following: hydrogen, halogen, (C1-C3) alkyl and (C1-C3) alkoxy, Z represents two hydrogen atoms or an oxygen atom.
Patent NZ-505099-A (NZ)
Title: Nutritive media and manufactured seeds comprising same
Inventor: CARLSON WILLIAM C
IPC: A01H4/00
Filed: 1998-11-20
Abstract: Manufactured seeds are disclosed that comprise a unit of totipotent plant tissue and a nutritive medium. The nutritive medium can contain a number of different components selected from a gel solute, charcoal, a carbon source, urea, KNO3, NH4NO3, CuCl2, CuSO4, KI, KH2PO4, CaCl2, MgSO4, Na2EDTA, FeSO4, ferric citrate, MnSO4, MnCl2, H3BO3, ZnSO4, CoCl2, Na2MoO4, (NH4)2MoO4, thiamine, riboflavin, pyridoxine.HCl, Ca-pantothenate, nicotinic acid, biotin, folic acid, and myo-inositol. The nutritive medium can also include any of various amino acids, polyamines, oxygen-absorbing compounds, and/or a smoke suspension.
Patent NZ-505123-A (NZ)
Title: Process for manufacturing bite-dispersion tablets by compressing medicaments and other ingredients into granulates then compressing the granulates and other ingredients into tablets, and the tablets thereof
Inventor: VENKATESH GOPADI M
IPC: A61K47/10
Filed: 1998-12-17
Abstract: A method for the manufacture of Bite-dispersion tablets which disperse easily and quickly in the oral cavity, after a gentle bite, without the aid of water, and if necessary includes masking the bitter taste of medicaments is disclosed, wherein the process comprises preparing a dry granulation of one or more of medicaments blended with suitable excipients, flavors and a combination of a waxy material and phospholipid (BMI-60) or an intense sweetener derived from fruit flavonoids (Neohesperidine) for taste-masking and compressing into tablets which can be packaged in bottles or blisters using conventional equipment.
Patent NZ-509766-A (NZ)
Title: Method for separating and characterising functions potentially present in a biological sample containing nucleic acids
Inventor: DUPRET DANIEL
IPC: C12Q1/68
Filed: 1999-08-11
Abstract: Process for the separation and characterization of the functions potentially present in a biological sample containing nucleic acids, characterized in that it comprises the steps of preparation of nucleic acid fragments starting from said sample, association of each one of said fragments with a vector molecule, isolation of each fragment associated with a vector molecule or with a part of each construction composed of a fragment associated with a vector molecule, in vitro treatment of each fragment associated with a vector molecule or of a part of each construction composed of a fragment associated with a vector molecule to obtain transcripts, and testing of the function of the transcripts or of the proteins encoded thereby after translation of said transcripts.
Patent NZ-516766-A (NZ)
Title: Method of cancer treatment
Inventor: CAMDEN JAMES BERGER
IPC: A61K31/4184
Filed: 2000-08-04
Abstract: Use of a pharmaceutical composition in preparation of a medicament for preventing cancer in a patient at risk. The pharmaceutical composition comprises a therapeutically effective amount of a compound of benzimidazole, as described in the specification.
Patent NZ-517308-A (NZ)
Title: Method to form a hydrophobic material to enhance surface hydrophobicity
Inventor: JONES ASHLEY WARD
IPC: C09D185/00
Filed: 2000-08-21
Abstract: A material capable of being applied to a surface is formed by: a) Providing precursors capable of reacting to form a gel. The precursors provided include at least water, a solvent and a metal alkoxide b) Reacting the precursors together to form a gel c) Adding a particulate material that is capable of chemically bonding with the gel to the gel to form a mixture. d) The mixture is treated so that a modified gel is formed in which the particulate material is bound to the gel. The modified gel is capable of forming a surface that is chemically hydrophobic and has a surface roughness. The surface roughness physically enhances the surface hydrophobicity so that water has a contact angle on the surface of at least 150o. A further step prior to step (d) can be included comprising mixing a polymer component and/or a surface modifier into the gel. The polymer component can bond with the gel and particulate material during step (d) and the surface modifier increases the intrinsic chemical hydrophobicity of a hydrophobic surface formed with the modified gel.
Patent NZ-523366-A (NZ)
Title: Secure transaction protocol
Inventor: VILJOEN ANDRE
IPC: G06F21/33
Filed: 2001-05-25
Abstract: A system for engaging in secure transactions over an internetwork, involving a Consumer, a Merchant and a Transaction Authority as parties to a transaction. To initiate the transaction the consumer makes an inquiry with the merchant who then returns a signed offer. The consumer then accepts the offer by also signing the offer. The doubly signed offer is then forwarded to the Transaction Authority. The Transaction Authority validates the transaction by checking both the authority and identity of the merchant and the consumer. The Transaction Authority then signs the offer to create a triply signed offer. The Transaction Authority returns the triply signed offer to the merchant. Once the merchant has a validated offer they are then able to request settlement of the transaction from the Transaction Authority, either immediately, or at some future date by sending a settlement request to the Transaction Authority.
Patent NZ-531194-A (NZ)
Title: Combination motif immune stimulatory oligonucleotides with improved activity
Inventor: KRIEG ARTHUR M
IPC: C12Q1/68
Filed: 2002-08-19
Abstract: A class of immunostimulatory nucleic acids having a CG-rich palindrome or CG-rich neutralizing motif. This class of combination motif immunostimulatory nucleic acids activates an immune response and is useful for treating a variety of immune related disorders such as cancer, infectious disease, and allergic disorders. The nucleic acids also stimulate activation of natural killer cells and production of type 1 interferon.
Patent NZ-532589-A (NZ)
Title: Tamsulosin tablets
Inventor: PLATTEEUW JOHANNES J
IPC: A61K9/28
Filed: 2002-11-01
Abstract: A pharmaceutical tablet obtained by a process without the use of a liquid, wherein said tablet comprises 0.1 to 1.5% tamsulosin active material and at least one pharmaceutically acceptable excipient.
Patent NZ-537872-A (NZ)
Title: Device and method for the reinforcing of support structures
Inventor: SCHWEGLER GREGOR
IPC: E04C5/12
Filed: 2003-06-25
Abstract: A device comprising a carbon-fibre sheet (4) for reinforcing support structures (1) is disclosed, said carbon-fibre sheet (4) terminating in an end fitting (3, 3'), whereby the ends of the carbon-fibre sheet (4) are provided with means for coupling (7) or with a bonding layer. The carbon-fibre sheet (4) lies pressed in the end fitting (3, 3') by means of at least one wedge (6, 6'). Coupling means (7) can take the form of glue, friction material with a particle size of 0.1 1.0 mm, a film provided with friction material, a powder coating or a plasma coating. Methods for reinforcement of support structures with said device, with or without pre-stressing are disclosed. The device is characterised in having a high flexibility on arrangement of the support structure for reinforcement and the methods is characterized by a rapid and very economical assembly.
Patent NZ-538376-A (NZ)
Title: Construction element for forming reinforced concrete slab
Inventor: HOUBEN EWALD
IPC: B65D1/24
Filed: 2003-09-15
Abstract: A construction element for forming a reinforced concrete slab, consisting of the combination of at least a hardened concrete layer (3), a number of reinforcement elements, and elements (5) extending at least partially from the concrete layer (3) and defining cavities is disclosed. The elements (5) are designed to be covered with concrete at a later stage. The elements (5) can be mutually nested.
Patent NZ-541667-A (NZ)
Title: The detection and identification of saxiphilins using saxitoxin-biotin conjugates
Inventor: ROBILLOT CEDRIC
IPC: C07D487/20
Filed: 2004-02-12
Abstract: Disclosed is a method of binding a saxiphilin protein obtainable from a source organism and a paralytic shellfish toxin moiety, including the steps of: (1) exposing a paralytic shellfish toxin conjugate comprising the paralytic shellfish toxin moiety bound via a linker comprising 5 atoms or more through a site other than the binding site for saxiphilin to a biotin moiety to a sample putatively comprising said saxiphilin and to (strept)avidin; and (2) allowing binding through the paralytic shellfish toxin moiety to the saxiphilin and through the biotin moiety to (strept)avidin; wherein the paralytic shellfish toxin conjugate comprising said linker comprising 5 atoms or more is characterised by a greater binding affinity for the saxiphilin compared with a paralytic shellfish toxin conjugate comprising a linker of 4 atoms or less. Also disclosed is a paralytic shellfish toxin conjugate for use in the method.
Patent NZ-541874-A (NZ)
Title: Thermostable and corrosion-resistant cast nickel-chromium alloy
Inventor: KIRCHHEINER ROLF
IPC: C22C19/05
Filed: 2004-01-22
Abstract: Disclosed is a nickel-chromium alloy for the production of castings comprising 0.26-0.8% carbon, up to 1.0% silicon, up to 0.2% manganese, 15-40% chromium, 0.5-13% iron, 1.5-7% aluminium, up to 2.5% niobium, up to 1.5% titanium, 0.01-0.4% zirconium, up to 0.06% nitrogen, up to 12% cobalt, up to 5% molybdenum, up to 6% tungsten, 0.019 to 0.089% yttrium, and the remainder nickel. The nickel-chromium alloy is highly carbonation-resistant and oxidation-resistant and highly thermostable, particularly resistant to creeping, in a carbonating and oxidising atmosphere even at temperatures exceeding 1130 DEG C.
Patent NZ-549175-A (NZ)
Title: Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
Inventor: ZELDIS JEROME B
IPC: A61K31/4035
Filed: 2003-05-16
Abstract: Disclosed herein is a use of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, or a pharmaceutically acceptable salt, solvate or stereoisomer thereof, for the manufacture of a pharmaceutical composition for the treatment of a cancer of the blood, non-HodgkinÆs lymphoma, ovarian cancer, pancreatic cancer, renal cancer, amyloidosis, cutaneous T-cell lymphoma, cutaneous B-cell lymphoma, diffuse large B-cell lymphoma and lung cancer.
Patent NZ-551265-A (NZ)
Title: Wood drying in the presence of supercritical carbon dioxide
Inventor: FRANICH ROBERT ARTHUR
IPC: F26B3/02
Filed: 2006-11-10
Abstract: Water and solutes are removed from the lumens of green wood by subjecting the green wood to supercritical carbon dioxide and removing water and solutes from the lumens of the wood whilst leaving the cell walls throughout the wood uniformly fully swollen. After the wood is dried down to about fibre saturation point (30 to 80% moisture content) by this method, further treatments can be applied to the wood and/or the wood can be dried by conventional methods to 12% moisture content.
Patent NZ-553531-A (NZ)
Title: Method for coating powders using supercritical or subcritical fluid
Inventor: CALDERONE MARILYN
IPC: A23L33/15
Filed: 2005-09-08
Abstract: Disclosed is a process for coating pulverulent solid active substances, characterized in that it comprises the following stages: a) providing a mixture comprising at least one coating agent in which is dissolved, up to saturation, a supercritical or subcritical fluid under temperature and pressure conditions which make it possible to maintain the said fluid under supercritical or subcritical conditions; b) providing separate moving particles of at least one pulverulent solid active substance; c) bringing the mixture and the separate moving particles of active substance into contact under temperature and pressure conditions which simultaneously ensure the reduction in pressure of the supercritical or subcritical fluid and its return to the gaseous state, the spraying of the coating agent and its solidification around the separate moving particles of active substance; (d) separating and recovering the coated particles.
Patent NZ-561391-A (NZ)
Title: Systems and methods for reducing upling resources to provide channel performance feedback for adjustment of downlink mimo channel data rates
Inventor: KIM BYOUNG-HOON
IPC: H04J99/00
Filed: 2006-03-13
Abstract: A method implemented in a multiple-input, multiple-output (MIMO) wireless communication system is disclosed. The method comprises transmitting each of a plurality of data streams from a first station to a second station in a permuted fashion over a plurality of MIMO channels; inversely permuting the data streams at the second station; determining a quality metric for each of the data streams at the second station; determining a condensed quality metric at the second station based on the quality metrics for each of the data streams; and transmitting the condensed quality metric from the second station to the first station. The transmitting the data streams in a permuted fashion comprises mixing the data streams on the MIMO channels in a pseudorandom pattern that comprises a full permutation of possible combinations of the data streams and the MIMO channels. Also disclosed is a method for multiple-input, multiple-output (MIMO) wireless communication. This method comprises encoding each of a plurality of data streams according to corresponding data rates; transmitting the data streams in a permuted fashion over a plurality of MIMO channels from a first station to a second station as described above; receiving a condensed quality metric; and adjusting the data rates at which the data streams are encoded based on the condensed quality metric. Further disclosed is a method for multiple-input, multiple-output (MIMO) wireless communication. The method comprises receiving a plurality of permuted data streams over a plurality of MIMO channels, inversely permuting the data streams; determining a quality metric for each of the data streams; determining a condensed quality metric based on the quality metrics for each of the data streams; and transmitting the condensed quality metric to a base station. The data streams are permuted by mixing the data streams on the MIMO channels in a pseudorandom pattern that comprises a full permutation of possible combinations of the data streams and the MIMO channels. A base station, mobile station and the multiple-input, multiple-output (MIMO) wireless communication system are also disclosed.
Patent NZ-565966-A (NZ)
Title: Chemical process for the preparation of benzoxazole derivatives
Inventor: FAROOQ SALEEM
IPC: C07D275/03
Filed: 2006-08-18
Abstract: Disclosed is a process for the preparation of a compound of formula (I), wherein Ra is C1-3alkyl, Rb is halogen, and wherein the other substituents are as described in the specification, comprising reacting a compound of formula (II) with a compound of formula (III) and an oxidising agent. Also claimed are intermediates used in the process.
Patent NZ-571496-A (NZ)
Title: Methods treating a crop kernel prior to milling to improve crop kernal millability, said method including the step of exposing the crop kernal to one or more plant hormones selected from an auxin and an abscisic acid
Inventor: SOUTHAN MICHAEL DAVID
IPC: A23L7/104
Filed: 2007-03-21
Abstract: Disclosed is a method of treating a crop kernel prior to milling to improve crop kernel millability, said method including the step of exposing the crop kernel to one or more plant hormones selected from the group consisting of an auxin and an abscisic acid which improves millability of the crop kernel.
Patent NZ-572583-A (NZ)
Title: Heat sealable inflator for heat sealing to an inflatable article
Inventor: FAWCETT LYMAN W
IPC: B67D99/00
Filed: 2007-04-27
Abstract: A heat sealable inflator 10 for heat sealing to an inflatable article, comprises a housing 12 having an integral peripheral flange 14 and a longitudinal bore 56, a sleeve 52 moulded in-situ with the housing 12, and a pierce pin assembly 54 reciprocatably positioned within the longitudinal bore 56. The sleeve 52 includes an exposed upper portion adapted to receive the neck of a gas cartridge and an embedded lower portion moulded in situ within the housing 12 about the longitudinal bore 56 to provide strength to it. The pierce pin assembly 54 is supported by the lower portion of the sleeve 52 to pierce a frangible seal of the gas cartridge whereupon release of the gas therefrom, the gas may flow through the inflator 10 and then out through an exhaust port of the inflator 10 into the inflatable article without contacting the embedded lower portion of the sleeve 52.
Patent NZ-574565-A (NZ)
Title: Hay and silage feeder with centre aligned pusher device to move rows of bales
Inventor: KENNA GERARD FRANCIS
IPC: A01D90/10
Filed: 2007-07-27
Abstract: Disclosed is a feeding device (10) for dispensing bales of material from a vehicle. The feeding device includes a body (12) having a surface for receiving a plurality of the bales. The surface has a first end (12a) and a second end (12b) and is configured such that the plurality of bales are arranged in a first (14) and a second row, each row extending between the first and second ends. A pusher (18) is slidably mounted to the surface between the first and second row, and is moveable between a first position proximal the first end and a second position proximal the second end. A controllable driving mechanism is provided to move the pusher between the first and second positions. Such movement of the pusher from the first position to the second position applies a pushing force to the bales arranged in one of the rows such that the bales in that row are progressively dispensed from the second end of the surface.
Patent NZ-577458-A (NZ)
Title: Acetylene derivatives and their use for binding and imaging amyloid plaques
Inventor: KUNG HANK F
IPC: A61P25/28
Filed: 2007-12-07
Abstract: Disclosed is a phenyl or pyridine acetylene compound of formula (I) where the substituents are as disclosed in the description. The compound must contain a halogen or halogen isotope. Also disclosed is a composition comprising a compound of formula (I); a diagnostic composition for imaging amyloid deposits comprising a radio labelled compound of formula (I) and the use of a compound of formula (I) for manufacturing a diagnostic composition. Amyloid detection is often used as a diagnosis for Alzheimer's disease.
Patent NZ-577689-A (NZ)
Title: Method of diagnosing Treponema palladium infection with lipid linked antigen
Inventor: HENRY STEPHEN MICHEAL
IPC: C07K7/08
Filed: 2010-09-10
Abstract: Disclosed is a method for determining the likelihood of infection of a subject with Treponema palladium comprising the steps of: Contacting a sample of the plasma or serum of the subject with a suspension of cells modified to incorporate a water soluble peptide-lipid construct of the structure F-S-L or L-S-F to provide a mixture; Incubating the mixture for a time and at a temperature sufficient to allow agglutination; and Determining the degree of agglutination of the cells in the mixture; where: F is a peptide comprising the sequence: AlaSerGlyAlaLysGluGluAlaGluLysLysAlaAlaGluGlnArgAlaLeuLeu (SEQID NO: 3); S is a spacer covalently linking F to L; L is a lipid selected from the group consisting of diacyl- and dialkyl-glycerophospholipids; and the degree of agglutination indicates the likelihood of infection of the subject.
Patent NZ-580602-A (NZ)
Title: Crenellated banded cigarette paper with merlons of the leading edge transversely aligned with crenels of the trailing edge
Inventor: ROSE MARC W
IPC: A24D1/02
Filed: 2008-05-29
Abstract: A wrapper 1 for a smoking article comprises a base web having a nominal permeability, and a banded region comprising sufficient add-on material such that the wrapper 1 has permeability at the banded region less than the nominal permeability of the base web. The banded region comprises a substantially continuous band that is about 4mm or less wide and a leading edge and a trailing edge of the banded region are crenelated. The merlons 20 of the leading edge are transversely aligned with crenels 16 of the trailing edge and crenels 14 of the leading edge are transversely aligned with merlons 24 of the trailing edge.
Patent NZ-581698-A (NZ)
Title: Polycyclic indazole derivatives and their use as erk inhibitors for the treatment of cancer
Inventor: PATEL MEHUL
IPC: A61K31/4245
Filed: 2008-06-04
Abstract: Disclosed are a selection of polycyclic indazole derivative compounds. Examples of such compounds include 1-(2-{ 4-[4-(5-Ethylamino-[1,3,4]oxadiazol-2-yl)-2-fluoro-phenyl]-3,6-dihydro-2H-pyridin-1-yl} -2-oxo-ethyl)-3-methoxy-pyrrolidine-3-carboxylic acid [3-(4-fluoro-phenyl)-1H-indazol-5-yl]-amide; and 1-(2-{ 4-[3-Fluoro-4-(5-fluoro-pyrimidin-2-yl)-phenyl]-3,6-dihydro-2Hpyridin-1-yl} -2-oxo-ethyl)-3-methoxymethyl-pyrrolidine-3-carboxylic acid [3-(2-cyclopropyl-pyridin-4-yl)-1H-indazol-5-yl]-amide. Further disclosed is the use of said compounds for the manufacture of a medicament for treating cancer.