baber/WOPTO huggingface dataset:
Patent GE-P20146181-B (GE)
Title: Anti cxcr4 antibodies for treatment of hiv
Inventor: KLINGUER-HAMOUR CHRISTINE
IPC: C07K16/28
Filed: 2010-04-29
Abstract: Present invention relates to novel isolated antibodies or derivatives thereof or functional fragments capable not only be bind with CXCR4, but also induce conformational changes of CXCR4 ho¬modimers and inhibition of HIV-1 primary isolate replication in PBMC. Particularly, present invention relates to 515H7 and 301aE5 monoclonal antibodies specific to CXCR4 protein, pharmaceutical compo¬sitions containing such antibodies, and their usage at HIV infection treatment, as well.  	16	dependent
Patent GE-P20156347-B (GE)
Title: Benzodioxane inhibitors of leukotriene production
Inventor: ABEYWARDANE ASITHA
IPC: C07D487/10
Filed: 2012-03-13
Abstract: There are represented benzodioxanes of common formula (I), pharmaceutical compositions containing them, which are inhibitors LTA4H and are applied for the treatment of various diseases stipulated with leukotrienes activity.
Patent CA-1317982-C (CA)
Title: Seal
Inventor: ADANG FRANCOIS M J
IPC: F16J15/32
Filed: 1985-01-22
Granted: 1993-05-18
Abstract: ABSTRACT            The invention is a seal for the gap between two parts which may or may not rotate with respect to each other which seal comprises a body of flexible material placed in a groove of one part and having a lip pressed against the surface of  the other part,  said  lip having a reinforcement of a more rigid material which towards the surface engaged by the lip has ridges of a smaller surface area than the areas turned away from said surface, said reinforcement eventually extending through some or all other parts of the seal to prevent extrusion into the gap.
Patent CA-1290364-C (CA)
Inventor: PLAQUIN BERNARD
IPC: E21B17/042
Filed: 1985-10-09
Granted: 1991-10-08
Abstract: The invention concerns a steel tube threaded joint particularly useful in the petroleum industry of the type in which the male element (3) and female element (1) are combined by threading (2, 4) wherein a portion of the surface of each thread is forcefully applied to the status of screwing to the thread of the outer element. A first element (1) of the joint has a composite structure and has on at least a certain length of its thread a lining of synthetic material whose volume and shape correspond exactly to the volume and shape of the existing clearance of the screwing status between the metal part and composite element (1) and the second element (3) having dimensions at the limit of the machining tolerances which allow the greatest possible clearance in the assembled state of the joint.
Patent CA-1279901-C (CA)
Title: Catheter for laser angiosurgery
Inventor: KITTRELL CARTER
IPC: A61B10/00
Filed: 1986-03-21
Granted: 1991-02-05
Abstract: CATHETER FOR LASER ANGIOSURGERY                         Abstract A laser catheter is disclosed wherein optical fibers carrying laser light are mounted in a catheter for insertion into an artery to provide controlled delivery   of   a   laser   beam   for   percutaneous intravascular  laser  treatment  of  atherosclerotic disease.  A transparent protective shield is provided at the distal end of the catheter for mechanically diplacing  intravascular  blood  and  protecting  the fibers from the intravascular contents,  as well as protecting the patient in the event of failure of the fiber optics.  Multiple optical fibers allow the selection of  tissue that  is  to be removed.   A computer  controlled  system  automatically  aligns fibers with the laser and controls exposure time. Spectroscopic diagnostics determine what tissue is to be removed.
Patent CA-1302416-C (CA)
Title: Platinum triamine antitumor agents
Inventor: HOLLIS LESLIE S
IPC: A61P35/00
Filed: 1986-04-15
Granted: 1992-06-02
Abstract: ABSTRACT OF THE DISCLOSURE         Charged triamine platinum (II) complexes containing a N-containing heterocyclic ligand such a pyridine or substituted derivative thereof have high solubility and aqueous stability and display antitumor activity.
Patent CA-1284979-C (CA)
Title: Metering valve
Inventor: SIMONELLI JAMES K
IPC: F16K1/04
Filed: 1986-04-30
Granted: 1991-06-18
Abstract: METERING VALVE                 Abstract of the Disclosure A metering valve having a one-piece bonnet for reducing problems resulting from tolerance stack up.  A guide portion is included on the nose of the bonnet for cooperation with a valve body bore to ensure concentric alignment between the metering pin and its associated orifice.  A pair of O-rings on the valve stem cooperate with the bonnet bore to absorb forces and substantially reduce the potential for galling and breakage of the metering pin.  One of the O-rings is compressed to a substantially greater extent than the other to aid in achieving better alignment between the stem and bonnet, and to obtain a firmer feel.  A handle is included at the outer end of the valve stem and receives an upper portion of the valve bonnet.  A packing is interposed between the handle and valve bonnet upper portion for limiting lateral movement between the handle and valve stem. The packing may be selectively adjusted without altering a preset deadstop position of the valve.
Patent CA-1339819-C (CA)
Title: 2-(pyrid-2-yl) methylthio (or methylsulfinyl)- benzimidazole derivativestheir production and use
Inventor: NOHARA AKIRA
IPC: A61K31/44
Filed: 1986-06-30
Granted: 1998-04-14
Abstract: The compound of the formula   wherein R1 is hydrogen, fluorine, methoxy or trifluoromethyl, R2 is a C1-8 alkyl, R3 is a C1-8 alkyl which may be fluorinated, and n is 0 or 1, or a pharmacologically acceptable salt thereof is useful for prevention and treatment of digestive ulcers (e.g. gastric ulcer, duodenal ulcer) and gastritis.
Patent CA-1284282-C (CA)
Title: Wavelength filter integrated into an optical waveguide
Inventor: LACROIX SUZANNE
IPC: G02B5/20
Filed: 1986-09-10
Granted: 1991-05-21
Abstract: ABSTRACT     The present invention relates to a wavelength filter integrated into an optical waveguide and to a method for manufacturing same.   The optical waveguide is  constituted  of  a  fiber  of  light  transmitting material on which is formed a plurality of biconical tapered  portions  which  constitute  the  wavelength filter.  The characteristics of the filter are governed by the number of biconical tapers and their respective profiles.  The tapers  are preferably formed by heating locally and stretching a conventional monomode optical fiber or by adding tapers in a monomode optical fiber, such as by splicing.
Patent CA-1288238-C (CA)
Title: Thick film conductor composition
Inventor: CRAIG WILLIAM A
IPC: C03C3/062
Filed: 1986-10-21
Granted: 1991-09-03
Abstract: TITLE THICK FILM CONDUCTOR COMPOSITION    ABSTRACT Thick film conductor compositions comprising an admixture of finely divided particles of A.  noble  metal,   noble  metal  alloy  or mixtures thereof, and B.  inorganic  binder  comprising  a  glass corresponding     to     the     formula Bi4Si3-xGex012,         having        ZnO dissolved therein, and C.  A  glass  bleed-out  inhibitor  selected from  pyrochlore-related  oxides,  metal resinates and mixtures thereof, all of A through C being dispersed in. D.  organic medium.
Patent CA-1279179-C (CA)
Title: Non-clay cat box filler
Inventor: LOWE HENRY E
IPC: A01K1/015
Filed: 1987-02-24
Granted: 1991-01-22
Abstract: NONCLAY CAT BOX FILLER                 Abstract Of The Disclosure A clay-like filler material formed from treated paper sludge or other fibrous slurries and a method of treating the sludge to form the filler which includes the physical properties of clay fillers.  The method involves adding materials to the shredded slurry to control color, basteria, fungi, absorbency, pests, and fragrance.  The slurry is then formed into granules and dried prior to being packaged.
Patent CA-1282200-C (CA)
Title: Batchwise preparation of crosslinked, finely divided polymers
Inventor: NOWAKOWSKY BERNHARD H
IPC: A61L15/00
Filed: 1987-03-17
Granted: 1991-03-26
Abstract: Abstract of the Disclosure:  Crosslinked, finely divided, water-absorbing polymers are prepared in a batchwise pro-cess by copolymerization of 100 parts by weight of a monomer mixture of acrylic acid or methacrylic acid, each of which is neutralized with from 0 to 100 mol% of an alkali metal or ammonium base, or acrylamide, methacryl-amide or N-vinylpyrrolidone with, as a crosslinking agent, from 0.01 to 5 parts by weight of a monomer con-taining two or more ethylenically unsaturated double bonds in 20-80% by weight aqueous solution in the pre-sence of an initiator in a multistage procedure in a batchwise mixing apparatus with constant thorough mixing in all stages, in the first stage the aqueous monomer solution being copolymerized at from 45 to 95°C and under from 0.1 to 0.8 bar with removal of some of the water by distillation, in the second stage the copolymerization being completed at from 100 to 170°C under a pressure of up to 8 bar, and in the third stage the water content of the resulting finely divided copolymer being decreased to 0.5-10% by weight under reduced pressure.
Patent CA-1285097-C (CA)
Title: Amorphous polyalphaolefin process
Inventor: OETTING STEVEN L
IPC: C08F6/28
Filed: 1987-05-25
Granted: 1991-06-18
Abstract: AMORPHOUS POLYALPHAOLEFIN PROCESS     ABSTRACT    A circulation loop is provided between a point next to the outlet of an amorphous polyalphaolefin polymerization zone and a flash zone, carrying a stream of molten devaporized polymer product.
Patent CA-1277644-C (CA)
Title: Bag-filling machine
Inventor: SPIESS JOACHIM
IPC: B65B1/18
Filed: 1987-06-02
Granted: 1990-12-11
Abstract: ABSTRACT OF THE DISCLOSURE           A bag-filling machine having an electronic weighing device which has a force receiver acting upon a bag support column.   The machine also has a bag support guide which comprises two upper parallel guides and two lower parallel guides which are disposed in each instance on both sides of the bay support column and whose bearings are constructed as articulated heads.  A possible lateral tilting of the bag support column is effectively prevented, without impairment of the vertical movement of this bag support column.   The two upper parallel guides and the two lower parallel guides are rigidly connected to one another by a respective coupling rod.
Patent CA-1338800-C (CA)
Inventor: HOUGHTON MICHAEL
IPC: C07K16/00
Filed: 1987-06-17
Granted: 1996-12-17
Abstract: The entire genome of the hepatitis D virus has been shown to be a circular single-stranded RNA of 1679 bases. Several open reading frames in both the genomic and complementary strands indicate possible protein products The products encoded in one open reading frame, ORF5, are identified as viral polypeptides p24? and p27?, of which the nuclear ? antigens in HDV infected liver is comprised. These products, as well as others encoded in ORFs 1, 2, 6, and 7 are produced in recombinant expression systems. The ORF5 products. in particular, are useful for HDV diagnosis and vaccines.
Patent CA-1283032-C (CA)
Title: Adaptor to endotracheal tube
Inventor: GREUNWALD THEODOR
IPC: A61M16/04
Filed: 1987-07-27
Granted: 1991-04-16
Abstract: ABSTRACT OF THE DISCLOSURE       The present invention relates to a simple device for ensuring the correct placement of endotracheal intubation.          According to the invention, there is a transparent adaptor suitable to be attached at one end to an endotracheal tube and at the other end to a mechanical respirator.  Into the adaptor there is a solid support impregnated with a solution of at least two chemical compounds:  organic amine and an indicator with a pK in the range of 2.0 to 10.5 of a concentration of at least: 0.05% (wt. by volume) of the impregnation solution.  The simplest form of solid support is a porous paper, such c-s filter paper, fiber or fabric.  The correct insertion of the endotracheal intubation. is noticed by the change in colour of the impregnated solution onto the solid support.  Optionally, the solution contains an inorganic alkali hydroxide, such as sodium hydroxide or potassium hydroxide, a humidifier and an organic solvent.  It is universal and can be attached to any existent endotracheal tube.
Patent CA-1335341-C (CA)
Title: Thermosetting high solids coating composition of hydroxy-functional epoxies and anhydrides
Inventor: BLACKBURN WILLIAM P
IPC: C09D163/00
Filed: 1987-08-14
Granted: 1995-04-25
Abstract: Disclosed herein is an improved process of preparing color-plus-clear coatings, the improvement comprising high solids thermosetting coating compositions comprising hydroxy-functional polyepoxides and anhydrides as effective curing agents therefor. Films of these coating compositions are of remarkable appearance and are attended by remarkably low volatile organic content (VOC).
Patent CA-1308351-C (CA)
Title: Aerosol for use in the reduction of tobacco smoking
Inventor: ROSE JED E
IPC: A24F47/00
Filed: 1987-08-19
Granted: 1992-10-06
Abstract: ABSTRACT OF THE DISCLOSURE     A  method  and  an  apparatus  and composition  used in the reduction   of   the  incidence  of  tobacco  smoking  and  which comprises  an  aerosol  for  application  to  the oral cavity and respiratory  tract of an individual.  The aerosol contains a food acid,  such as citric acid, which is present in non-toxic amounts and  capable of being inhaled.  The aerosol may be in the form of a  liquid  spray  or  a  finely  divided  solid.  The droplets or particles    contained in the aerosol are of proper size and have the  food  acid  sufficient in content to simulate the sensations in  the upper respiratory tract caused by tobacco smoke.  In this way,  the  oral  cavity  sensations  and  the  respiratory  tract sensations  simulate  those  created  by tobacco smoke to replace the  need  for  tobacco  smoke.    In  another  embodiment of the invention  the food acid aerosol contains tobacco smoke of proper particle  size  so  that  the  food acid particles migrate to the respiratory  tract  and  the  tobacco  smoke  remains in the oral cavity.    In  still  a  further embodiment of the invention, the aerosol   contains  small  particles  of  a  carrier  such  as  a saccharide with tobacco smoke adsorbed thereon.
Patent CA-1287436-C (CA)
Title: Colloidal stable vinyl halide polymerizations with mercaptan chain transfer agents
Inventor: SHARABY ZAEV
IPC: C08F14/00
Filed: 1987-08-27
Granted: 1991-08-06
Abstract: ABSTRACT OF THE DISCLOSURE Polymers of vinyl halides having low molecular weights, good particle characteristics, and improved melt flow are made by aqueous polymerization utilizing an effective amount of a mercaptan as a chain transfer agent, wherein the mercaptan chain transfer agent is mixed with at least one material which is non-polymerizable with vinyl chloride and wherein said non-polymerizable material is substantially insoluble in water and is miscible with said mercaptan to form a chain transfer composition, and said chain transfer composition is added before the start of the polymerization while maintaining colloidal stability.
Patent CA-1277781-C (CA)
Inventor: JIN SUNGHO
IPC: H01R13/24
Filed: 1987-08-27
Granted: 1990-12-11
Abstract: Abstract:          Electrical interconnection is established by means of an anisotropically conductive, composite layer medium comprising electrically conductive particles in a nonconductive matrix material.  Enhanced uniformity of conductivity across the medium, and minimized incidence of lateral shorting are achieved as a result of essentially uniform distribution of electrically conductive particles which are also magnetic, such distribution resulting upon application of a magnetic field essentially perpendicular to a layer before or during hardening of the matrix material.
Patent CA-1292993-C (CA)
Inventor: PERREGAARD JENS K
IPC: A61K31/445
Filed: 1987-09-11
Granted: 1991-12-10
Abstract: THE ACETIC ACID ESTER OF HALOPERIDOL     A B S T R A C T  O F  T H E  D I S C L O S U R E   The present invention relates to the novel acetic acid ester of 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone, as well aspharmaceutically acceptable acid addition salts thereof, a method of pre-paration, pharmaceutical compositions and a method of treating psychoses by administering said ester to an animal or human body.
Patent CA-1334783-C (CA)
Inventor: ZIEBOLD STEVEN A
IPC: C01B/
Filed: 1987-09-18
Granted: 1995-03-21
Abstract: A method and apparatus for the recovery of heat from a sulfuric acid process are provided. Sulfur trioxide is absorbed into hot concentrated sulfuric acid, acid having a concentration greater than 98% and less than 101% and a temperature greater than 120C, in a heat recovery tower and the heat created by the exothermic reaction is recovered in a useful form in a heat exchanger.  Gas leaving the primary heat recovery absorption zone is cooled by contact with sulfuric acid in a secondary absorption and cooling zone located above the primary absorption zone in the tower.
Patent CA-1290088-C (CA)
Title: Process for catalysing cationic paint binders
Inventor: SCHIPFER RUDOLF
IPC: C09D5/02
Filed: 1987-10-16
Granted: 1991-10-01
Abstract: ABSTRACT OF THE DISCLOSURE     Cationic paint binders, particularly binders of the type used in cathodic electrodeposition coatings which crosslink through transesterification, transamidation, transurethanization, or through the reaction of chain end double bonds catalyzed with a reaction product of lead(II) oxide with compounds carrying .beta.-hydroxyamino structure are described.  The catalysts of the invention provide very good stability and good compatibility in aqueous cationic paint materials.
Patent CA-1339263-C (CA)
Title: Fusion proteins and particles
Inventor: KINGSMAN ALAN J
IPC: C07K16/00
Filed: 1987-10-30
Granted: 1997-08-12
Abstract: Fusion proteins comprise a first amino acid sequence and a second amino acid sequence.  The first amino acid sequence is derived from a retrotransposon or an RNA retrovirus and confers on the fusion protein the ability to assemble into particles; an example is the product of the TYA gene of the yeast retrotransposon Ty.  the second amino acid sequence is biologically active;  for example it may be antigenic.   So particles  formed of the  fusion proteins may be useful in vaccines or in diagnostic or purification applications.
Patent CA-1322165-C (CA)
Title: Method for treating iron overload
Inventor: ADAMSON JOHN W
IPC: A61K38/22
Filed: 1987-11-18
Granted: 1993-09-14
Abstract: ABSTRACT         A method for reducing stored iron and serum iron in mammals is disclosed.  In particular, a mammal having an iron overload disorder is administered a therapeutically effective amount of erythropoietin to increase red blood cell production and the mammal is subsequently phlebotomized to remove the excess red blood cells produced.
Patent CA-1282819-C (CA)
Title: Line scanner to reduce banding
Inventor: LEE DENNY L Y
IPC: G06K15/12
Filed: 1987-11-19
Granted: 1991-04-09
Abstract: IMPROVED LINE SCANNER TO REDUCE BANDING                 ABSTRACT OF THE DISCLOSURE A control system for an electrophotographic exposure apparatus is characterized by a film sheet transport which carries a film sheet past a first and a second spaced position whereat the same portion of the film sheet is exposed to an imaging beam each having the same image information.
Patent CA-1294102-C (CA)
Inventor: HARTMAN STEVEN
IPC: B29C44/60
Filed: 1988-04-18
Granted: 1992-01-14
Abstract: ABSTRACT OF THE DISCLOSURE        The synthetic plastic foam products are extruded in a manner to cause a controlled increase in the area of the product after being extruded through a die orifice. This controlled increase in cross sectional area is limited by a shaping horn which engages the product as it is foaming and limits the cross section of the final product.  A lubricant is introduced to reduce friction and avoid adhesion of the product to the shaping horn.
Patent CA-1298768-C (CA)
Inventor: RAUTENBERG LEONARD J
IPC: B32B5/04
Filed: 1988-05-17
Granted: 1992-04-14
Abstract: ABSTRACT          The invention relates to a laminated elastic fabric comprising:  a layer of stretch material having substantial elastic qualities; a polymer film layer having a thickness less than 1.0 mil, said film layer being breathable and water-resistant and having elastic qualities comparable to said stretch material; and an adhesive bonding said film layer to said layer of stretch material, said adhesive being present in substantially discontin-ous segments and a method for producing the fabric.  Such fabrics are water-proof or water-resistant but have the ability to pass moisture vapour therethrough.
Patent CA-1300796-C (CA)
Title: Ladder polysilanes
Inventor: NAGAI YOICHIRO
IPC: C07F7/08
Filed: 1988-06-01
Granted: 1992-05-12
Abstract: ABSTRACT OF THE DISCLOSURE      There is here disclosed a ladder polysilane represented by the general formula   (I):                        (I) wherein n is a positive integer, and R is a halogen atom, a hydrogen atom, a hydroxyl group, an alkyl group, an alkenyl group, an aryl group or an alkoxy group having 20 or less carbon atoms, and the alkyl, alkenyl, aryl or alkoxy group may contain a functional group such as -COOH, -SO3H, -NH2, -NO2, -NCO, -F, -Cl, -Br, -I or -OH.  In addition, a method for preparing the aforesaid ladder polysilane is also disclosed here.
Patent CA-1302934-C (CA)
Title: Process for preparing pitches
Inventor: TSUCHITANI MASATOSHI
IPC: C10C3/00
Filed: 1988-06-08
Granted: 1992-06-09
Abstract: ABSTRACT OF THE DISCLOSURE        Commercially attractive continuous processes for the preparation  of  mesophase  pitches  for  manufacturing high-performance carbon fibers are disclosed.  One feature resides in  that  conversion  of  a pitch  into  a mesophase pitch  is conducted continuously by using a unique continuous dispersion-heat-treating apparatus.   The other feature resides in that the  raw  material  for  hydrogenation  treatment  which  is  a pretreatment preceeding to the final heat treatment for the production of a mesophase pitch, is prepared by using a heavy oil or pitch having substantially no BTX-insoluble material as the starting raw material, subjecting the raw material to a simple four-step treatment of (1) a continuous heat treatment in a tubular heater,  (2) a distillation operation,  (3) a BTX-solvent extraction and  (4) a distillation operation; while recycling a soluble component obtained in the step (4) to the heat  treatment  of  step  (1)  and  recovering  a  BTX-solvent insoluble component formed in step (3) as the material for the hydrogenation  treatment.    This  feature  can  provide  a significant  increase  in  the  yield of  a  mesophase  pitch. Furthermore,   unexpectedly,   the  recycle  of  the  soluble component into the heat treatment of step  (1)  is helpful to improve the characteristics of the ultimate products,  i.e., carbon fibers or graphite fibers.  Combination of the first and the second  features,  of course,  can provide a better commercial  success.   In  fact,  the process of the present invention can provide a carbon fiber having a tensile strength of more than 300 kg/mm2 and a graphite fiber having a tensile strength of more than 400 kg/mm2 and a modulus of elasticity of more than 60 ton/mm2.  Processes with minor modifications to the above are also disclosed.