baber/WOPTO huggingface dataset:
Patent CA-2446872-A1 (CA)
Title: Immune-modulating peptide
Inventor: RYU SUNG-HO
IPC: A61P11/06
Filed: 2003-01-28
Abstract: Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood monocytes or neutrophils; binds to formyl peptide receptor or formyl peptide receptor-like 1; that induce chemotactic migration of human monocytes or neutrophils in vitro; that induce degranulation in formyl peptide receptor expressing cells or formyl peptide receptor-like 1 expressing cells; that stimulate extracellular signal regulated protein kinase phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1; or that stimulate Akt phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1.
Patent CA-2449475-A1 (CA)
Title: Method and system for design selection by interactive visualization
Inventor: MCCONAGHY TRENT LORNE
IPC: G06F17/50
Filed: 2002-06-17
Abstract: A method and system for electronic circuit design selection by interactive visualization. The present invention is particularly appropriate for learning the performance and behaviour of analog circuits, and for selecting a preferred design from a dataset of candidate designs derived from a multi-objective optimization. The method consists of providing a multidimensional dataset from a multiobjective optimization, or otherwise. The multidimensional dataset is then displayed as a plurality of plots. The plots can be one-dimensional, or multi-dimensional, and can include parallel coordinate plots.  By modifying at least one of the plots, the user can interactively select an evaluation dataset for further evaluation or testing. The modification can take the form of interactive filtering to reduce the dataset in a desired manner. Typically, this is done through a graphical interface, by visual selection, brushing, etc. It can also include defining or constructing constraints of one or more variables in the multidimensional dataset. The constraints can include linear and non-linear. This modification and selection process can be repeated as necessary to further restrict the dataset to a manageable number of candidate designs.
Patent CA-2450029-A1 (CA)
Title: Vessels and covers
Inventor: COSTA ALVIN
IPC: C02F1/50
Filed: 2002-05-17
Abstract: Vessels (10), or housings, and covers therefor are detailed herein. Loads and load-bearing surfaces exist principally at the periphery of the covers (22), by contrast with centralized loadiing utilized in other designs. In some versions of the vessels (10), a cover (22) is sandwiched, at its periphery (P2), between a cap assembly (26) formed of both a jack ring (42) and an upper component or cap (38) and thus carried on and off the associated vessel (10) when the cap (38) is placed onto or removed from the vessel (10), respectively.
Patent CA-2451584-A1 (CA)
Inventor: PHILIPPS MARTIN
IPC: A61K48/00
Filed: 2003-11-28
Abstract: Modified human factor VIII cDNA wherein mutations are inserted either in the wild-type factor VIII cDNA or in a factor VIII cDNA in which the B-domain is partially or completely deleted and may be replaced by a DNA linker segment and A) one or several codons of the human factor VIII cDNA which are not identical with the corresponding codon in the same position of the porcine factor VIII cDNA are substituted by a different codon in such a way that .cndot. when the human sequence contains a codon for a neutral amino acid whereas the porcine sequence contains a codon for a charged amino acid then a codon for an amino acid with the same charge as found in the porcine sequence is introduced into the human sequence;   .cndot. when the human sequence contains a codon for a charged amino acid whereas the porcine sequence contains a codon for a neutral amino acid then a codon for a neutral amino acid or a codon for an amino acid of t he opposite charge is introduced into the human sequence, .cndot. when the human sequence contains a codon for a charged amino acid whereas the porcine sequence contains a codon for an amino acid with the opposite charge then a codon for an amino acid with the opposite charge is introduced into the human sequence or B) one or several codons for a charged amino acid which are found in the FVIII cDNA of a hemophilic patient are replaced by a codon for an amino acid of the opposite charge.
Patent CA-2451811-A1 (CA)
Title: Method and apparatus for applying a threaded cap to a threaded neck of a container
Inventor: MAVIN GERRY
IPC: B67B3/20
Filed: 2003-12-02
Abstract: There is described a method of applying a threaded cap to a threaded neck of a container. The method comprises the steps of placing the cap on the neck of the container, rotating the cap relative to the neck in an opening direction whilst supporting the cap with respect to the neck; and applying the cap to the neck so as to achieve substantial thread engagement.      There is also described an applicator for applying a threaded cap to a threaded neck of a container and reverse drive mechanism for use with an applicator.
Patent CA-2451962-A1 (CA)
Title: Ecl labels having improved non-specific binding properties, methods of using and kits containing the same
Inventor: TJIONG HOWIE
IPC: G01N27/416
Filed: 2002-06-21
Abstract: Bipyridine or phenanthroline ligands presenting functional groups that prevent non-specific binding (in particular, negatively charged functional groups that are unaffected by standard conditions for conjugating biological reagents through amide bonds) are described as are luminescent metal complexes comprising these ligands. The use of luminescent ruthenium and osmium complexes comprising these ligands in electrochemiluminescence assays shows that the use of these labels can significantly reduce the amount of non-specific binding observed relative to assays carried out using reagents labeled with analogous labels that don't present functional groups that decrease non-specific binding.
Patent CA-2454158-A1 (CA)
Inventor: GEMMELL RENIA
IPC: C12P7/56
Filed: 2002-07-18
Abstract: Cette invention se rapporte à une bactérie capable de convertir des sucres en acide lactique ou en un sel de cet acide. Cette invention concerne également un procédé servant à produire de l'acide lactique ou un sel de cet acide et consistant à cet effet à cultiver ladite bactérie. Cette invention concerne en particulier une bactérie thermophile capable de convertir au moins 70 % (en poids) d'un sucre monosaccharide et d'un sucre disaccharide en acide lactique ou en un sel de cet acide.
Patent CA-2454244-A1 (CA)
Inventor: REIME GERDE
IPC: G06F3/0346
Filed: 2002-07-09
Abstract: The invention relates to an optoelectronic device which comprises several transmitters (A-D) and at least one receiver (E) for detecting the position and movement of an object. Various light paths are created between the transmitters and the receiver, the transmitters being driven by a timing circuit with an oscillator (10). An evaluation device detects the movement of the object on a surface two-dimensionally. For the three-dimensional detection of the position and/or the movement of the object, the timing circuit switches the transmitter and receiver to another cycle so that the space into which the transmitter radiates is evenly illuminated, as far as possible. Based on the rays reflected by the object during the other cycle, the evaluation device establishes a value for determining the distance (d) of the object (O) from the surface (figure 7) by taking a value into account, said value being detected shortly before the object came into contact with the surface.
Patent CA-2457111-A1 (CA)
Title: Vaccin
Inventor: VINALS Y DE BASSOLS CARLOTA
IPC: C07K19/00
Filed: 2001-10-24
Abstract: L'invention concerne de nouveaux médicaments destinés au traitement, à la prévention ou à l'atténuation des allergies. Ces nouveaux médicaments sont notamment des épitopes ou des mimotopes dérivés d'IgE. Les nouvelles régions concernées peuvent servir de cible à l'immunoprophylaxie ou à l'immunothérapie, active ou passive. L'invention concerne également des procédés de préparation de médicaments, des compositions pharmaceutiques les contenant et leur utilisation en médecine. L'un des aspects de la présente invention couvre des ligands, notamment des anticorps monoclonaux, qui sont capables de lier les régions IgE selon la présente invention, et leur utilisation en médecine en immunoprophylaxie passive ou en immunothérapie passive.
Patent CA-2457823-A1 (CA)
Title: Methods for diagnosing and treating neoplasias using nf-at transcription factors
Inventor: SERFLING EDGAR
IPC: C12Q1/6886
Filed: 2002-08-12
Abstract: Described is a method for diagnosing a neoplasia by determining whether the level of one or more NF-AT transcription factor(s) is reduced. Moreover, methods for screening compounds which activate an NF-AT or which mimic the function of NF-AT are disclosed. Also disclosed are methods for the prevention or treatment of neoplasias by increasing the activity of an NF-AT.
Patent CA-2458312-A1 (CA)
Title: Method and apparatus for blow-molding an article having a solid radially outwardly projecting flange
Inventor: CLOUGHERTY KENAN J
IPC: B65D1/40
Filed: 2004-02-20
Abstract: A solid outwardly projecting flange is formed on the side wall of a blow- molded article by providing a blow mold having a circumferential groove that is filled by flowable thermoplastic during a blow cycle. The mold includes a heating system locally disposed adjacent the groove for heating the walls of the groove so as to heat the thermoplastic in this region, thereby reducing the viscosity of the thermoplastic so that it more-readily flows into and completely fills the groove. The mold can also include a cooling system disposed locally adjacent the groove for cooling the flange of the blow-molded article prior to ejection of the article from the mold.
Patent CA-2460024-A1 (CA)
Title: Conveyor belt
Inventor: MEEKER WILLIAM A
IPC: B65G17/06
Filed: 1996-05-22
Abstract: A conveyor belt (20), particularly suited to the food processing industry, includes a tension-bearing framework of transversely extending rods (36-38,141,168,172,177) connected to tension bearing interconnected links (45) into which is attached a series of loose-fitting modular product support members (23-25,134,138).  The product support modules include forwardly and rearwardly extending link ends (27,30) such that successive modules are interfitted with one another. Each of the forwardly and rearwardly extending link ends are provided with slotted longitudinal openings (76,77,82) through which the transverse rods extend. The distance between a front wall portion defining the slot in a forwardly extending link end and a rear wall portion defining the slot in an associated rearwardly extending link end is greater than the fixed longitudinal spacing spanned by adjacent transverse rods so as to permit some relative longitudinal movement between the conveyor modules and the rods. In addition, at least one of the modules and the rods are provided with standoff elements (84,136,143,170,174,179) which define a minimum contact area between the modules and the rods. This limited contact area creates larger openings between the conveyor modules and the rods such that when the conveyor belt is passed through a washing unit (15), washing sprays can effectively reach all surfaces. In addition, since the conveyor modules are permitted to shift longitudinally relative to the rods, this further enhances the elimination of debris trapping zones such that a highly sanitary conveyor belt arrangement is obtained. In addition, unique end cap members (47) are provided to prevent relative rotation between drive links associated with the conveyor belt and the transverse rods.
Patent CA-2461836-A1 (CA)
Title: Detection and treatment of intravascular lesions
Inventor: WEISSKOFF ROBERT M
IPC: A61K38/08
Filed: 2002-10-16
Abstract: Optical agents that contain a fibrin binding moiety covalently linked to an optical dye are described, as well as methods of treating intravascular lesions in a patient using such optical agents.
Patent CA-2462321-A1 (CA)
Title: Methods and computer program products for converting an initial object of an initial type to a final object of a final type
Inventor: PURDY DOUGLAS M
IPC: G06F9/45
Filed: 2004-03-25
Abstract: Methods, systems, and computer program products for converting an object of one type to an object of another type that allow for the runtime operation of the conversion process to be altered or customized. The conversion may occur within an extensible serialization engine that serializes, deserializes, and transforms objects of various types. The runtime operation of the serialization engine is altered by one or more extension routines that implement the desired customizations or extensions, without requiring replacement of other existing routines. Based on type information, identified for an initial object, the object is converted to an intermediate representation which permits runtime modification, including modification of object names, object types, and object data. The intermediate representation of the initial object is modified in accordance with extension routines that alter the runtime operation of the serialization engine, and the intermediate representation is converted to a final object and type.
Patent CA-2462482-A1 (CA)
Title: Oral dosage form for propiverine or its pharmaceutically acceptable salts with an extended release of the active ingredient
Inventor: GRUBER PETER
IPC: A61K31/445
Filed: 2002-10-08
Abstract: By suitable retardation oral pharmaceutical compositions containing propiverine or one or several pharmaceutically acceptable salts thereof in an amount of 4 mg to 60 mg propiverine and having a prolonged release of the active agent are produced.  Preferably a blend of active agent and optionally one or more acidic substances having a pK a value of less than 6.65 are provided with a retarding coating or are embedded in a matrix which is then optionally coated with further retarding layers.
Patent CA-2462979-A1 (CA)
Title: Hair treatment process and use of the process for smoothing the hair
Inventor: DEVIN-BAUDOIN PRISCILLE
IPC: A45D7/06
Filed: 2004-04-07
Abstract: Hair treatment comprises applying a ceramide composition, heating the hair above 60[deg]C with a flat or round iron, and optionally rinsing the hair before or after heating.
Patent CA-2467735-A1 (CA)
Title: System and method for interpreting sales data through the use of natural language questions
Inventor: FOURNIER CHRISTOPHER D
IPC: G06Q30/00
Filed: 2002-10-01
Abstract: A sales management data analysis system and method for interpreting raw sale s management data are provided. A plurality of natural language questions are provided, wherein each of the natural language questions correspond to at least one database query. An at least one database is queried in accordance with a selected one of the plurality of natural language questions. A particular data set is created responsive to the querying of the at least on e database in accordance with the one of the plurality of natural language questions from the at least one database. And the particular data set is sen t to a destination, the particular data set configured to be able to provide a particular visual interpretation thereof, wherein the particular visual interpretation is of a particular type.
Patent CA-2468232-A1 (CA)
Inventor: TANG JOHN
IPC: G06F7/14
Filed: 2002-05-09
Abstract: L'invention concerne une mémoire FIFO (100) recevant des demandes de transfert de données avant que les données ne soient stockées dans une mémoire FIFO. Plusieurs transferts de données simultanés exécutés vers la mémoire FIFO, en tant qu'opérations simultanées entrelacées, peuvent être adaptées par la mémoire FIFO (c'est-à-dire, par multiplexage entre différentes sources qui transmettent les données par rafales réparties). Les exigences quant à la durée du transfert (130, 132, 134) associée aux transferts de données en cours sont recherchées, y compris l'espace disponible total dans la mémoire FIFO. Une zone de mémoire tampon programmable peut également être incorporée dans la mémoire FIFO afin d'assurer une protection supplémentaire contre le débordement et/ou un étalonnage dynamique de la profondeur de la mémoire FIFO.
Patent CA-2468444-A1 (CA)
Title: Eye speculum
Inventor: SINDING PAUL
IPC: A61B17/02
Filed: 2002-12-10
Abstract: An eye speculum comprising a moulded flexible shell (2,5) configured for insertion into an eye socket so as to contact and envelop part of an eyeball , the shell (2,5) having an opening (3) therein to provide access to the eyeba ll for ocular surgery or examination.
Patent CA-2469116-A1 (CA)
Title: Three-piece motion control truck system
Inventor: SCHORR RALPH
IPC: B61F5/14
Filed: 2004-05-28
Abstract: An improved three-piece truck system for railroad cars provides long travel side bearings for improved stability, a "wide" friction shoe design or equivalent to improve sideframe and bolster squareness, a resilient pedestal pad for improved curving performance and enhanced wear resistance, and a suspension system tuned and optimized for rail cars to have a minimum reserve capacity of less than 1.5 to improve motion control and ride quality, increase resistance to suspension bottoming, and increase hunting threshold speed. Such a motion control truck system is able to meet recent more stringent American Association of Railroads standards, such as M-976, for railcars having a 286,000 lb. gross rail load rating.
Patent CA-2470027-A1 (CA)
Inventor: LOTT JOHN S
IPC: G16H40/20
Filed: 2004-06-04
Abstract: A management system is used for management of patients on waiting lists in such fields as elective surgery, diagnostic services, clinic services and endoscopies. The system also administers administrative entities based on aggregate data provided by the system. The system has data entry, list management, audit and reporting functions. It acquires and creates its data. It calculates much data dynamically (in real time). For example, it stores data on when a patient entered onto a waiting list, and a patient's urgency score. Based on the urgency score, it calculates a target date for the patent. It dynamically (in real time) calculates the number of days a patient is from the target date, and ranks the patients accordingly. It filters a list of patients awaiting procedures according to various resource criteria. It provides for and manages referrals between systems, and lists, in different fields, and it allows calendar booking.
Patent CA-2474153-A1 (CA)
Inventor: SABI YUICHI
IPC: G11B20/00
Filed: 2003-01-22
Abstract: Sans modifier considérablement les spécifications d'informations enregistrées sur un support d'enregistrement optique sous forme de disque ayant été traité de façon conventionnelle à l'aide d'un lecteur spécialisé, le support d'enregistrement optique sous forme de disque de cette invention permet de limiter la reproduction par un lecteur de disque appartenant à un ordinateur et d'empêcher la copie non autorisée. Une chaîne de creux déformée contenant une oscillation et un décalage spéciaux d'une chaîne de creux d'une piste d'informations est formée en tant que zone limite de lecture. Dans cette zone limite de lecture, durant une rotation à faible vitesse du support d'enregistrement optique en forme de disque, le suivi est possible à l'aide d'une commande de poursuite de captage optique et une reproduction correcte est possible. Cependant, durant une rotation à grande vitesse du support d'enregistrement optique en forme de disque, il est impossible d'effectuer un suivi par commande de poursuite de captage optique pour effectuer la reproduction.
Patent CA-2474659-A1 (CA)
Title: Fragments d'acides nucleiques pour l'identification de bacteries de dechloration
Inventor: EBERSOLE RICHARD
IPC: C12Q1/68
Filed: 2002-01-30
Abstract: Un profil d'ARNr 16S unique dérivé de Dehalococcoides ethenogenes a été identifié et isolé. Le profil contient plusieurs fragments d'acide nucléique lesquels sont liés à une activité de déchloration. Ces séquences sont présentées dans SEQ ID NO:1, SEQ ID NO:8, SEQ ID NO:30 et SEQ ID NO:34.
Patent CA-2474753-A1 (CA)
Inventor: CAREY VINCENT MARK
IPC: F02C7/00
Filed: 2003-02-07
Abstract: A device and a method for real time optimizing engine lubricating oil properties in response to actual engine operating conditions. The present invention is a method that comprises measuring, directly or indirectly, a system parameter of interest near a location of interest, calculating from said parameter(s) or input(s) the amount of a secondary fluid selected from performance enhancer(s), additional base lubricant, alternatively formulated lubricant or diluent that need be added to the base lubricant; and supplementing said base lubricant with said secondary fluid before introducing the combination into said monitored location.
Patent CA-2475366-A1 (CA)
Title: Interacting with software applications displayed in a web page
Inventor: BEHRAKIS ELIAS C
IPC: G06F9/50
Filed: 2003-02-06
Abstract: The invention enables the display of application-output data within application-output windows (326) embedded in a web browser window (320). The application-output windows (326) can be dynamically moved, resized and otherwise manipulated within the web browser window (320) even when the application program providing the source of the application-output data is non-web enabled (e.g., legacy applications). The invention receives window attribute information associated with the application-output windows (326) via a first virtual channel (660) and displays application-output data received via a second channel (670) within the application-output windows (326), which are formed and/or modified using the window attribute information.
Patent CA-2477053-A1 (CA)
Inventor: SCHAUB ANDREAS F
IPC: A61K9/08
Filed: 2003-01-21
Abstract: L'invention concerne l'utilisation d'une substance organique physiologiquement neutre pour produire une composition exempte de sels de métaux alcalins de métaphosphates, servant de lubrifiant lors d'accouchements par voie vaginale chez la femme. Cette composition facilite et accélère l'accouchement. Mélangée à des principes actifs pharmaceutiques, elle permet en outre de prévenir les infections et d'atténuer la douleur.
Patent CA-2477218-A1 (CA)
Title: Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective mao inhibitors
Inventor: HERZIG YAACOV
IPC: A61K31/22
Filed: 2003-02-27
Abstract: The subject invention provides derivatives of propargylamino indan (PAI) and propargylamino tetralin that selectively inhibit monoamine oxidase (MAO) in the brain, having the structure:, wherein R1 is OC (O) R9 and R2 is H, wherein R9 i s branched or unbranched C1 to C6 alkyl, aryl, or aralkyl, or R1 is OC  (O) R4 and R2 is OC (O) R4, wherein R4 is branched or unbranched C1 to C6 alkyl, aryl, aralkyl or NR5R6, wherein R5 and R6 are each independently H, C1 to C8 alkyl, C6 to C12 aryl, C6 to C12 aralkyl or C6 to C12 cycloalkyl, each optionally substituted; wherein R3 is H or C1 to C6 alkyl; wherein n is 0 or 1; and wherein m is 1 or 2, or a pharmaceutically acceptable salt thereof.  Additionally, the subject invention provides methods of treating neurological disorders using these compounds, uses of these compounds for the manufacture of medicaments for treating neurological disorders and processes for synthesis of these compounds.
Patent CA-2478547-A1 (CA)
Title: Identification of high affinity molecules by limited dilution screening
Inventor: ZHANG LI
IPC: G01N33/68
Filed: 2002-12-02
Abstract: Methods are disclosed for determining the relative binding affinities of molecules for their binding partner. One type of molecule is an antibody, which has an antigen binding partner. Antibodies are tested for binding against limited dilutions of antigen. Antibodies that bind to the most dilut e antigen concentrations are determined to have a higher relative binding affinity for the antigen than antibodies that only bind to more concentrated antigen preparations.