baber/WOPTO huggingface dataset:
Patent PT-959132-E (PT)
Title: Nucleic acid encoding receptor type protein kinase
Inventor: YOKOTA SHOHEI
IPC: C07K14/705
Filed: 1997-10-13
Abstract: To provide a nucleic acid encoding a receptor protein kinase, wherein the nucleic acid has tandem duplication in a nucleotide sequence of a juxtamembrane and is useful for diagnosis of leukemia; a polypeptide encoded by the nucleic acid; an antibody capable of specifically binding to a region encoded by the nucleic acid having tandem duplication occurring in a nucleotide sequence of a juxtamembrane; a nucleic acid capable of specifically binding to the nucleic acid having tandem duplication occurring in a nucleotide sequence of a juxtamembrane; a method for detection of the nucleic acid encoding a receptor protein kinase; and a kit therefor. A nucleic acid encoding a receptor protein kinase, wherein the nucleic acid has tandem duplication in a nucleotide sequence of a juxtamembrane; a polypeptide encoded by the nucleic acid; an antibody capable of specifically binding to the portion of the polypeptide; a nucleic acid capable of specifically binding to the nucleic acid; a method for detection of the nucleic acid; and a kit for detection.
Patent PT-944645-E (PT)
Inventor: GOLEC JULIAN M C
IPC: A61P31/04
Filed: 1997-12-05
Abstract: The present invention relates to novel classes of compounds which are inhibitors of interleukin-1beta converting enzyme ("ICE"). This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against interleukin-1-("IL-1"), apoptosis-, interferon-gamma inducing factor-(IGIF), interferon-gamma-("IFN-gamma") mediated diseases, excess dietary alcohol intake diseases, or viral diseases, including inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, and degenerative diseases. This invention also relates to methods for inhibiting ICE activity and decreasing IGIF production and IFN-gamma production and methods for treating interleukin-1, apoptosis- and interferon-gamma-mediated diseases using the compounds and compositions of this invention. This invention also relates to methods of preparing the compounds of this invention.
Patent PT-1038001-E (PT)
Inventor: BENJAMIN ROVINSKI
IPC: C12N15/49
Filed: 1998-12-14
Abstract: Non-infectious, non-replicating immunogenic HIV-like particles are produced by stable long-term constitutive expression in mammalian cells by eliminating elements toxic to the mammalian cells. An expression vector contains a nucleic acid molecule comprising a modified HIV genome devoid of long terminal repeats and wherein Tat and vpr sequences are functionally disabled and a constitutive promoter operatively connected to the modified HIV genome for constitutive expression of the modified genome to produce the HIV-like particles.
Patent PT-970711-E (PT)
Inventor: LLANOS GERARD H
IPC: A61F2/82
Filed: 1999-06-29
Abstract: A process is provided for coating stents having a first and second surface with passages there between to avoid blockage and bridging of the passages. The process comprises contacting the stent with a liquid coating solution containing a film forming biocompatible polymer under conditions suitable to allow the film forming biocompatible polymer to coat at least one surface of the stent while maintaining a fluid flow through said passages sufficient prevent the film forming biocompatible polymer from substantially blocking said passages. Also described are stents coated by this process.
Patent PT-1018662-E (PT)
Inventor: NOTHOFER KLAUS DIPL ING
IPC: G02B6/44
Filed: 1999-12-09
Abstract: Optical cable (1), with core strands (2) of sheathed loose bundles (5) comprising tightly sheathed parallel non-stranded fibers (6). Optical cable (1) has core strands (2), comprising bundles (5) loosely arranged in a first sheath (4). Each bundle comprises parallel non-stranded fibers (6) tightly enclosed by a thin wall second sheath (7).  An Independent claim is also included for production of the optical cable.
Patent PT-1071349-E (PT)
Inventor: PAUL MORRIS
IPC: D03D15/56
Filed: 1999-04-14
Abstract: A method of making a fabric composite capable to assuming a desired shape including the steps of forming an interlining fabric (10) containing elastic yarn (15) running longitudinally of the fabric, varying the density of yarn across the width of the interlining to control the longitudinal extensibility across the width, and attaching the interlining to a fabric backing material (12).
Patent PT-1082300-E (PT)
Inventor: RUNGE THOMAS A
IPC: A61P31/04
Filed: 1999-05-27
Abstract: This invention provides a novel and useful purification step in the manufacture of a diamine pyrrolidine side chain intermediate for a quinolone antibiotic that allows production of the antibiotic in significantly greater yields and at lower costs than was previously possible. Salts, procedures and processes for preparing them, including the salt disclosed in Formula A-1, below, are also disclosed.
Patent PT-1119279-E (PT)
Inventor: PLANCA RINALDO
IPC: A47J43/07
Filed: 1999-10-02
Abstract: The invention is related to an electrical appliance from the type blender of food processor, comprising a base including an electric motor, a container able to be removably secured on said base, said container having a cylindrical open top, a food processing tool mounted in the bottom of said container and able to be driven by said motor, a lid able to close said container, means for limiting axial movement of the lid, means for limiting rotational movement of the lid, a safety device including a pin mounted on the container and a switch mounted on the base, the lid including means for actuating the pin to operate the switch in order to enable motor operation when the lid occupies a closed operating position on the container, wherein a locking button is provided on the container, said button being able to actuate a lock able to bear against an abutment or to enter a notch, said notch or said abutment being provide on the lid, to lock the lid on the container in the closed operating position.
Patent SG-86490-G (SG)
Title: Single lens having one aspherical surface
IPC: G02B3/04
Filed: 1990-10-24
Abstract: A single lens is described for the formation of a scanning spot on an information surface of a transparent record-carrier substrate. The lens has one aspherical surface and one spherical or plane surface. The curvatures of the lens surfaces and the thickness of the lens are such that a compensation is obtained for aberrations caused by the substrate.
Patent IE-850008-L (IE)
Title: Crop processor
IPC: A01D34/42
Filed: 1985-01-02
Abstract: An auger cutter, windrower, and conditioner for standing crops such as hay, including a cutting auger with cutting teeth on the peripheral edge of the auger flight and a conveyor auger to move cut crop to a central area to be discharged as a double windrow.
[US4550554A]
Patent IE-38802-L (IE)
Title: Catalase determination in a liquid
IPC: G01N33/50
Filed: 1974-01-29
Abstract: PURPOSE: To provide a biaxially oriented polyethylene 2,6-naphthalate film excellent in modulus of elasticity and tear strength which is useful for magnetic recording and electrical insulation. CONSTITUTION: The objective polyethylene 2,6-naphthalate film contains main recurring units of ethylene 2,6-naphthalate blended with compd. having at least 3 ester-forming functional groups per molecule[JPS5025293A]
Patent IE-40578-L (IE)
Title: New x-ray contrast agents
IPC: C07C231/00
Filed: 1975-02-04
Abstract: The radiopaque substance is 3,6,9-trioxaundecane-1,11-diolyl bis(3-carboxy-2,4,6-triiodoanilide) or its salts with physiologically tolerated bases. The X-ray contrast medium is prepared by reacting 3-amino-2,4,6-triiodobenzoic acid with a reactive derivative of 3,6,9-trioxaundecane-1,11-dioic acid and converting the reaction product where appropriate with salt formation, into a form suitable for intravenous administration. The medium can be used in particular for radiological diagnosis of seriously injured patients with impaired liver function.
[GB1501507A]
Patent IE-880224-L (IE)
Title: Process producing activated killer cells.
IPC: C12N5/02
Filed: 1988-01-28
Abstract: There is disclosed an improved process for preparing lymphokine activated killer cells or tumor-infiltrating lymphocytes, the improvement comprising culturing precursor cells in a closed container made form copolymeric film material having a specified O2 permeability, selected from specified materials, and having a thickness of from about 0.04 mm to about 0.23 mm.
Patent IE-800362-L (IE)
Title: Therapeutic compositions
IPC: A61K31/53
Filed: 1980-02-22
Abstract: A therapeutic composition with cytostatic action comprising an isocyanurate having the formula I   <IMAGE> in which R, R', and R'' which may be the same or different represent hydrogen or alkyl having from 1 to 4 carbon atoms, preferably hydrogen or methyl in an inert pharmaceutically acceptable diluent, carrier or vehicle. The compositions may also contain other alkylating substances such as derivatives of nitrogen mustard or fluoruracil.
Patent IE-840733-L (IE)
Title: Protective sleeve for an information carrier
IPC: G11B23/033
Filed: 1984-03-26
Abstract: 1. An abrasion-resistant sleeve for an information carrier, in particular for a magnetic data carrier, comprising an antistatic nonwoven fabric which has been consolidated without a binder by pointlike thermal welding only, which has a surface resistance of less than 10**9 ohms at up to temperatures above 100 degrees C, and contains electro-conductive polypropylene, polyester, viscose and/or polyamide fibres which contain from 20 to 40% by weight, based on the total weight, of finely divided carbon black incorporated during spinning.
Patent IE-870793-L (IE)
Title: 1-styrenesulphony1-2-oxo-5-hydroxy pyrrolidine
IPC: C07D207/48
Filed: 1987-03-27
Abstract: The therapeutic compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures or old age and excessive intellectual fatigue having the formula (I): <IMAGE> (I) in which R1 represents an alkyl radical, linear or branched, containing up to 8 carbons atoms, an acyl radical containing from 1 to 6 carbon atoms or a cycloalkyl radical containing from 3 to 6 carbon atoms and R represents an aryl radical containing up to 14 carbon atoms, unsubstituted or substituted, or a mono- or polycyclic heterocyclic radical, unsubstituted or substituted. Also, therapeutic compositions containing the compound, method of preparing the compound and method of use.
[US4810722A]
Patent IE-900846-L (IE)
Title: Combination therapy for the treatment of estrogen sensitive¹diseases
IPC: A61K31/047
Filed: 1990-03-09
Abstract: A method of treatment of breast and endometrial cancer in susceptible warm-blooded animals may include inhibition of ovarian hormonal secretion by surgical (ovariectomy) or chemical (use of an LHRH agonist, e.g. [D-Trp6, des-Gly-NH210]LHRH ethylamide or antagonist) as part of a combination therapy comprising administering an antiestrogen together with at least one compound selected from the group consisting of an androgen, a progestin, at least one inhibitor of sex steroid formation, especially 17 beta -hydroxysteroid dehydrogenase and aromatase activity, at least one inhibitor of prolactin secretion, one inhibitor of growth hormone secretion and one inhibitor of ACTH secretion. Pharmaceutical compositions useful for such treatment and pharmaceutical kits containing such composition are disclosed.
Patent IE-850966-L (IE)
Title: Organic compounds.
IPC: A61K31/66
Filed: 1985-04-16
Abstract: Compounds of the general formula <CHEM> wherein X is C1-C6, straight chain saturated or unsaturated hydrocarbyl group, the group R<4> and the group Y are situated in any position in this chain and wherein at least one of the hydrogen atoms in X can be a heavy isotope of hydrogen; R<4> is hydrogen or an alkyl, alkoxy, hydroxy, aryl, aryloxy, aralkyl, aralkoxy, aralkylamino, or morpholino group wherein the alkyl or aryl part of any one of said groups may be substituted by one or more halogeno groups; or R<4>, together with at least one carbon atom of the group X, forms a carbocyclic or heterocyclic ring of 5 to 6 ring atoms; Y is an acidic or related group giving rise to one or more electronegative sites in the group; or R<4>-X-Y represents a carboxylic acyl group; R<1> is hydrogen or an alkyl, haloalkyl, aryl, haloaryl, aralkyl or haloaralkyl; R is hydrogen or an alkyl, haloalkyl, aryl, haloaryl, aralkyl or haloaralkyl group; R<2>, R<3> and R<5> which may be the same or different is each hydrogen or an alkyl, hydroxy, alkoxy, carboxy, alkyloxycarbonyl, halo, aryl, haloaryl or aryloxycarbonyl group; or R<2> and R<3> together with the carbon atoms to which they are attached form a ring system or R<3> and R<4> together and/or R<3> and X together form one or more than one ring system, and physiologically acceptable salts thereof have activity in the central nervous system.
[EP0159889A2]
Patent IE-32318-L (IE)
Title: Benzenesulphonyl ureas
IPC: C07C311/59
Filed: 1968-08-08
Abstract: Benzenesulphonylureas and their suitable salts. (I) R1 = 4, 7-endomethyleneperhydroindan-5-yl opt. 6-Cl, 4, 7-endomethyleneperhydroindan-2-yl, 2, 6-endomethylenecycloheptyl, 4, 4-Me2-DELTA2-cyclohexenyl, DELTA2-cyclopentenyl/heptenyl/octenyl, norcaran-7-yl, bicyclo (5.1.0) octyl (8)/(6.1.0) nonyl (9)/(4.2.0) octyl (7), 2, 5-endocyclobutylene (1, 2) cyclohexyl, Me/3, 3-Me2/3-Et/3-t-Bu/2-Cl-cyclopentyl, DELTA2-cyclopentenylmethyl, bicyclo-(2.1.1) pentyl (2), spiro (2-cyclopropane/butane/pentanepentyl), cyclopropryl/butyl, 5-Me-DELTA2-cyclohexenyl, bicyclo (3.1.0) hexyl; X = Ph, opt. substd. by Z and Z' where Z = H, halogen, alkyl, alkoxy, alkenoxy, alkoxyalkoxy, phenalkoxy, acyl, PhCH2, CF3, OH and Z' = CN, NO2, H, halogen, alkyl, alkoxy, alkoxyalkoxy, OH; thienyl opt. mono/disubstd. by alkyl, alkoxy, alkoxyalkoxy, alkenoxy, phenalkoxy, halogen; Y = CH2CH2, CH2CHMe or CHMe. CH2.
[CH545774A]
Patent FI-823831-L (FI)
Inventor: APPELT HORST GUSTAV
IPC: A44B11/14
Filed: 1982-11-09
Abstract: A clamping buckle for straps, particularly shoulder straps on articles of clothing, with two buckle sections which are swingable with respect to each other around a transverse buckle axis, the buckle sections having a clamping position for clamping the strap. The buckle sections lie one on top of the other approximately parallel to each other with the formation of a gap therebetween. The buckle sections have respective gap sides which face the gap and respective outsides which face away from the gap, and they have slots and bars for diverting the straps including a bar in one buckle section opposite a slot in the other buckle section. The bar of the first buckle section is aligned on its gap side with a plane of the first buckle section and is of at least the same width as the slot of the other buckle section. A loop of the strap wraps around the bar and includes loop end portions passing through the slot that extend by the outside of the second buckle section.
Patent FI-845004-L (FI)
Inventor: TIKKANEN MATTI HAAKON AUGUST
IPC: A61K8/40
Filed: 1984-12-18
Abstract: Tartar formation on teeth is prevented with compositions of a sodium salt ethylenediaminetetraacetic acid having a pH between about 5.5 and 9.0 in a carrier which permits application to the teeth. Aqueous solution may be used for this purpose as well as toothpaste compositions.
Patent IE-791056-L (IE)
Title: Pharmaceutical package
IPC: A61J1/03
Filed: 1979-08-08
Abstract: A packaging element is provided for mounting blister strips containing a course of medication for a patient. The element comprises a lamina foldable along a straight line dividing the lamina into a supporting member and backing member so that when the lamina is folded the one faces of the member lie adjacent. The element is characterized in that the supporting member is provided with a plurality of apertures for receiving the blisters of a plurality of blister strips when the blister strips are mounted on the one face of the supporting member so that the blisters project through the member and form a matrix in which the blister strips are aligned with the columns of the matrix, and the backing member is provided with a plurality of apertures arranged so that when blister strips are mounted on the supporting member and the lamina is folded the contents of the blisters may be removed through the backing member, the one faces of the members bearing a compatible pressure-sensitive adhesive capable of securing blister strips to the two members and of bonding together the one faces of the two members, the other face of the supporting member bearing or being adapted to receive in relation to each row of the matrix directions as to the day on which the contents of the blisters in the row are to be administered and further being adapted to receive directions in relation to each column of the matrix as to the time of administration of the contents of blisters in the column, the element further characterized in that it comprises one or more protective release sheets strippably adhered to the pressure-sensitive adhesive. (From US4254871 A) [FR2427273A1]
Patent IE-811337-L (IE)
Title: Semiconductor device
IPC: H01L23/31
Filed: 1981-06-16
Abstract: A semiconductor device comprising memory circuits coated with a resinous film for shielding these circuits from the radioactive rays formed in substrate material. The resinous film is divided into a plurality of portions which are separated from one another and further coats at least memory cells and sense amplifiers. In one of the embodiments a part of the resinous film is removed at the portion of the chip other than said memory cells and sense amplifiers.
[US4481526A]
Patent IE-35854-L (IE)
Title: Microbiological production of proteins
IPC: A23J1/00
Filed: 1971-11-29
Abstract: Growth of bacteria belonging to new species of genera Pseudomonas, Microcyclus and Hyphomicrobium upon culture media comprising sources of assimilable carbon, for example oxygenated hydrocarbons, and inorganic nutrients to produce protein compositions and/or other fermentation products, for example amino acids. The protein compositions produced are suitable for use as protein supplements in human and animal foods.
[US4317843A]
Patent IE-35855-L (IE)
Title: Copolymer suture
IPC: D01F4/00
Filed: 1971-11-29
Abstract: 1375008 Filaments of lactide/glycollide copolymers ETHICON Inc 16 Dec 1971 [18 Dec 1970 16 Nov 1971] 58564/71 Heading B5B [Also in Divisions C3 and D1] A packaged suture comprises a sterile absorbable surgical suture in an internally sterile package, the suture being a braided multifilament thread consisting of filaments made by extruding a copolymer obtained by copolymerizing glycollide and L(-)lactide and containing 10-15 mole per cent of lactide and having an inherent viscosity of at least 1�4, as determined on a 0�1 per cent solution in hexafluoroisopropanol at 25� C. The filaments are extruded, stretched, annealed, braided, optionally further stretched and annealed, and sterilized by exposure to a wet atmosphere of a fluorochloralkane and ethylene oxide. The filaments may be dyed by addition of a non- toxic dye to the polymer mixture. The copolymerization reaction between the L(-)lactide and glycollide is carried out in a dry container under a blanket of dry nitrogen and is catalysed using stannous octoate. Several examples of reaction conditions are given in the Specification. The copolymer melt is extruded using a screw feed hopper, a metering pump, and a die with the appropriate number of orifices. Several examples of extrusion conditions are given in the Specification. The suture material is cut to suitable length and sterilely packaged with a surgical needle.
[GB1375008A]
Patent IE-821608-L (IE)
Title: Thin-wall sleeves forming apparatus
IPC: B21D15/02
Filed: 1982-07-01
Abstract: Apparatus (22,22') for forming thin-wall sleeves (24) is disclosed as including a spring biaser (52) for tools (48) of the apparatus. A mandrel (36) and a tool housing (42) cooperate to mount the sleeve (24) for forming under the impetus of an actuator (54) that moves the tools (48) against the force of the spring biaser (52). Upon such tool movement, forming ends : (50) of the tools form the sleeve (24) into circumferentially spaced recesses (40) of the mandrel to provide sleeve splines or teeth (56). The spring biaser (52) preferably includes a plurality of springs (92) mounted within associated spring openings (98) in the tool housing between tool slots (46) in which the tools (48) are supported for movement. in one embodiment, the forming is performed inwardly with the sleeve mounted about an internal mandrel. In another embodiment, the forming is performed outwardly with the sleeve mounted within an external mandrel.
Patent IE-831954-L (IE)
Title: Diagnostic device
IPC: G01N33/52
Filed: 1983-08-22
Abstract: A diagnostic device for the detection of an increased concentration of dehydrogenases and/or oxidases in the fluids of humans, animals or plants, which consists of a carrier which bonds a redox dyestuff, and a substance mixture, adjusted to a pH value in the acid range, of the substrate corresponding to the particular dehydrogenase, a hydrogen donor compound and at least one redox dyestuff is described. The device has the peculiarity that the carrier contains polar groups and the substance mixture for detecting exclusively pathologically increased concentrations of the particular dehydrogenase and/or oxidase is adjusted to a pH value of below 5.0. The device is suitable for diagnosing malignant growths in very different organs, for example in the female genital area.
Patent IE-45788-L (IE)
Title: Piperidine and pyrrolidine aminoglycosides
IPC: C07H15/236
Filed: 1977-10-06
Abstract: PURPOSE:Aminoglycoside antibiotics derivatives of formula I[A and B are the residual saccharide parts of the aminoglycosides;X is II(R is H or lower alkyl) or III] having 2-deoxystreptamine skeleton, and their nontoxic salt, e.g. 1-N-(4-hydroxypiperidine-4-carbonyl) kanamycin A.
[JP53056661A]
Patent IE-38516-L (IE)
Title: Propylamine-substituted pyridines.
IPC: C07D213/38
Filed: 1973-11-15
Abstract: 1429068 3-Mono- or di - bromophenyl - 3- (3 - pyridyl) - 1 - (dimethylamino) - propanes HASSLE AB 15 Nov 1973 [16 Nov 1972] 53096/73 Heading C2C Novel compounds of Formula VII wherein R<SP>1</SP> is H or Br and salts thereof are prepared by reaction of dimethylamine with a compound of Formula IX: which is obtained by hydrogenation of a compound of Formula VIII: Pharmaceutical compositions in conventional forms for oral, rectal or parenteral administration and having anti-depressant activity comprise an above novel compound and a carrier or diluent.
[GB1429068A]
Patent IE-42219-L (IE)
Title: Production of wood pulp
IPC: D21C3/26
Filed: 1975-09-24
Abstract: Chemical cellulose is produced by treatment in a digester. In the first step, wood in the form of chips is treated for a period of about from 15 to 90 minutes with a cooking acid of a calculated amount of below 5% by weight and at least 2.5% by weight of SO2 and a mole ratio of SO2 to MgO or CaO of from about 2 : 1 to 3.5 : 1 at a temperature of from about 45 to 90 DEG C. The liquid SO2 is fed into the digester until the total SO2 content of the cooking acid is from about 6 to 10 percent by weight, and completing the digestion in a second step to obtain a pulp by cooking at a temperature of above 110 DEG C., and working up the pulp in a manner known per se to obtain chemical cellulose.
[US4141787A]