baber/WOPTO huggingface dataset:
Patent CA-3105999-A1 (CA)
Title: Nut for joining conduits
Inventor: BRIARS BRADLEY JAMES
IPC: F16B37/00
Filed: 2021-01-19
Abstract: Abstract NUT FOR JOINING CONDUITS       A nut for joining conduits includes a body having a generally cylindrical shape and defining a central opening. A plurality of lugs can extend outwardly from an outer surface of the body and provide one or more strike surfaces. The central opening can include a threaded portion proximate a first end of the nut and a tapered portion extending from the threaded portion. The tapered portion defines a frustoconical surface that expands the central opening beyond the threaded portion. The tapered portion may terminate at an undercut or flange proximate the second end of the nut. Date Recue/Date Received 2021-01-19
Patent CA-3107417-A1 (CA)
Inventor: YAMAGUCHI TATSUYA
IPC: C07K16/32
Filed: 2019-07-24
Abstract: The present invention is: a method for manufacturing an antibody-drug conjugate in which a drug linker represented by formula (1) (A in the formula representing an antibody binding site) and an antibody are bonded by a thioether bond, the manufacturing method characterized by including (i) a step for reducing an antibody with a reducing agent, (ii) a step for reacting a drug linker intermediate with the antibody reduced in step (i), (iii) a step for adding a reagent having a thiol group and reacting with the drug linker intermediate remaining from step (ii), and (iv) a step for then removing a byproduct derived from the drug linker intermediate by ultrafiltration using a buffer solution containing a salt comprising a strong acid and a strong base; and a method for manufacturing a pharmaceutical composition including the aforementioned antibody-drug conjugate.
Patent CA-3108807-A1 (CA)
Title: Procedes pour evaluer le risque de developper une leucoencephalopathie multifocale progressive provoquee par le virus de john cunningham par des procedes de test genetique pour ev aluer le risque de developper une leucoencephalopathie multifocale progressive provoquee par le virus de john cunningham par test genetique
Inventor: HATCHWELL ELI
IPC: C12Q1/6883
Filed: 2019-08-08
Abstract: L'invention concerne des méthodes et des matériels liés au traitement d'une maladie. Par exemple, l'invention concerne des procédés de traitement d'une maladie d'un sujet sur la base de l'identification du risque de leucoencéphalopathie multifocale progressive, PML, à l'aide d'un test génétique.
Patent CA-3108904-A1 (CA)
Title: System and method for retail price optimization
Inventor: SAARENVIRTA KARI
IPC: G06Q10/04
Filed: 2021-02-10
Abstract: A computer system and computer-implemented method for retail merchandise planning, including promotional product selection, price optimization and planning. According to one or more embodiments, the computer system for generating an electronic retail plan for a retailer comprises, a data staging module configured to input retail sensory data from one or more computer systems associated with the retailer; a data processing module configured to pre-process the inputted retail sensory data; a data warehouse module configured to store the inputted retail sensory data and the pre-processed retail sensory data; a state model module configured to generate a retailer state model for modeling operation of the retailer based on the retail sensory data; a calibration module configured to calibrate the state model module according to one or more control parameters; and an output module for generating an electronic retail plan for the retailer based on the retailer state model.
Patent CA-3112800-A1 (CA)
Inventor: WILLEMSEN PETRUS THEODORUS JOHANNES
IPC: A61P31/20
Filed: 2019-09-18
Abstract: The invention is directed to a recombinant nucleic acid molecule comprising an expression cassette encoding a polyepitope comprising T-cell antigens from proteins of African Swine Fever Virus. The invention further relates to a viral particle, comprising said recombinant nucleic acid molecule, and to a viral particle comprising B-cell antigens of African Swine Fever Virus. The invention further relates to methods of stimulating an immune response in a pig comprising administering the recombinant molecule of the invention, and/or the viral particle of the invention, to the pig in an amount effective to induce an immune response.
Patent CA-3113025-A1 (CA)
Inventor: HENNESSY EDWARD J
IPC: A61K9/14
Filed: 2019-09-19
Abstract: The present disclosure in part provides compounds (i.e., PEG lipids) which are useful in pharmaceutical compositions, cosmetic compositions, and drug delivery systems, e.g, for use in lipid nanoparticle (LNP) formulations. The present disclosure also provides LNP formulations comprising PEG lipids described herein, and methods of using the same. For example, the LNPs provided herein are useful for the delivery of an agent (e.g, therapeutic agent) to a subject. The PEG lipids and LNPs provided herein, in certain embodiments, exhibit increased PEG shedding compared to existing PEG lipids and LNP formulations.
Patent CA-3116749-A1 (CA)
Title: Hla-a3-restricted t cell receptors against mutated ras
Inventor: HANADA KENICHI
IPC: C07K14/725
Filed: 2019-10-24
Abstract: Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated RAS amino acid sequence presented by a HLA-A3 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Patent CA-3118952-A1 (CA)
Inventor: MACK RANDALL J
IPC: A61K9/14
Filed: 2019-11-07
Abstract: The disclosure provides methods of treating pain in a first subject in need thereof, comprising administering meloxicam to the first subject, wherein the first subject has a platelet dysfunction. In some embodiments, a closure time of platelets isolated from the first subject before administration of meloxicam is more prolonged than a closure time of platelets isolated from an otherwise similar subject without platelet dysfunction. In some embodiments, the closure time of platelets isolated from the first subject after administration of meloxicam is comparable to a closure time of platelets isolated from the first subject before administration of meloxicam.
Patent CA-3122750-A1 (CA)
Title: Fourier transform device and fourier transform method
Inventor: TAKAHASHI KATSUMI
IPC: G06F17/14
Filed: 2019-01-24
Abstract: According to the present invention, pieces of ((k-1) M+1)-th (k=1, ···, K) data in an alignment order with each piece of first data taken as a start point are respective pieces of forefront data in K data columns(1k) among K×M data (where K is an integer of 3 or greater, and M is an integer of 2 or greater), and the K data columns (1k) include respective M pieces of data at M intervals in an alignment order with each piece of the forefront data taken as a start point among K×M data. According to the present invention, a Fourier transform device is configured to be provided with: an adder (2) which calculates a total sum of K pieces of data that are pieces of m-th (m=1, , M) data in an alignment order with the forefront data as the start point among M pieces of data respectively included in the K data columns (1k); and a transformer (3) which performs an M-point Fourier transform for each of the total sums calculated by the adder (2) and performs an inverse M-point Fourier transform for each of the total sums.
Patent CA-3123154-A1 (CA)
Title: Fuel cell unit having flanged perimeter features and fuel cell stack
Inventor: REES LEE DAVID
IPC: H01M8/1286
Filed: 2019-12-03
Abstract: A metal-supported, SOEC or SOFC fuel cell unit (10) comprising a separator plate (12) and metal support plate (14) with chemistry layers (50) overlie one another to form a repeat unit, at least one plate having flanged perimeter features (18) formed by pressing the plate, the plates being directly adjoined at the flanged perimeter features to form a fluid volume (20) between them and each having at least one fluid port (22), wherein the ports are aligned and communicate with the fluid volume, and at least one of the plates has pressed shaped port features (24) formed around its port extending towards the other plate and including elements spaced from one another to define fluid pathways to enable passage of fluid from the port to the fluid volume. Raised members (120) may receive a gasket (34), act as a hard stop or act as a seal bearing surface.
Patent CA-3129357-A1 (CA)
Title: Liquid pharmaceutical formulations of pth conjugates
Inventor: SKANDS ANJA R H
IPC: A61K9/00
Filed: 2020-02-10
Abstract: A liquid pharmaceutical formulation, wherein the pharmaceutical formulation comprises a PTH conjugate, a buffering agent, an isotonicity agent, a preservative and optionally an antioxidant and wherein the PTH conjugate comprises a PTH moiety that is covalently and reversibly conjugated to a water-soluble carrier moiety.
Patent CA-3129899-A1 (CA)
Title: Intelligent event tracking system
Inventor: LIU YIMIN
IPC: G06F17/00
Filed: 2020-12-16
Abstract: A first computing system may determine that a first event is represented in first data received from a second computing system. Based at least in part on the first event being represented in the first data, the first computing system may generate a time-ordered schedule of events that includes an indication of the first event, and may send, to a client device, second data representing the time-ordered schedule of events.
Patent CA-3129908-A1 (CA)
Title: Method and system for detection and/or quantification of delta-9-tetrahydrocannabinol in exhaled breath
Inventor: DWEIK BADAWI M
IPC: G01N27/26
Filed: 2020-02-11
Abstract: Method and system for detecting and/or quantifying ?9-tetrahydroeannibinoi (THC) in exhaled breath. In one embodiment, the method involves providing an electrochemical sensing element, the electrochemical sensing element including a working electrode, and also providing a filter that traps THC in exhaled breath. Next, a subject exhales onto the filter, whereby at least some of the THC, if present, is trapped in the filter. Next, the filter is washed with an eluent, whereby at least some of the THC trapped in the filter is eluted in an eluate. Next, the eluate is deposited onto the working electrode of the electrochemical sensing element, and the eluate is dried, whereby any THC present is immobilized on the working electrode. Next, an electrolytic solution is delivered to the electrochemical sensing element, and the THC immobilized on the working electrode is directly electrochemically detected and/or quantified using a pulse voltammetry technique, such as square-wave voltammetry.
Patent CA-3130644-A1 (CA)
Title: Wheel arrangement for a rail vehicle
Inventor: BIEKER GUIDO
IPC: B61F3/04
Filed: 2020-02-19
Abstract: The present invention relates to a wheel arrangement for a rail vehicle, in particular, a light rail vehicle, comprising a wheel unit (107) and an axle unit (108). The axle unit (108) is configured to be connected to a running gear structure of the rail vehicle, wherein the axle unit (108) rotatably supports the wheel unit (107). The axle unit (108) comprises a wheel bearing unit (108.1), wherein the wheel bearing unit (108.1) forms a bearing for the wheel unit (107) and defines a wheel axis of rotation (107.1) of the wheel unit (107) during operation of the rail vehicle. The axle unit (108) comprises a wheel support unit (108.3) and a primary suspension unit (105), wherein the primary suspension unit (105) is located kinematically in series between the wheel support unit (108.3) and the wheel bearing unit (108.1), such that the wheel support unit (108.3) supports the wheel bearing unit (108.1) via the primary suspension unit (105) in a manner resilient in at least two mutually transverse translational degrees of freedom.
Patent CA-3133030-A1 (CA)
Title: Pseudo-particules de norovirus a stabilite amelioree
Inventor: JARCZOWSKI FRANZISKA
IPC: C07K14/08
Filed: 2020-03-11
Abstract: L'invention concerne une protéine de capside VP1 de génogroupe I de norovirus ayant une séquence d'acides aminés dans laquelle la longueur de séquence d'acides aminés dans le domaine P Ala-Ala-Leu-Leu/Val-His-Tyr est modifiée en Ala-Ala-Leu-LeuNal-Arg/Lys-Tyr.
Patent CA-3133056-A1 (CA)
Inventor: GALLAGHER ERIC
IPC: A61G3/00
Filed: 2020-03-26
Abstract: The present disclosure relates to a method and system for monitoring the status of a person in the vicinity of a vehicle, including capturing an image of an area in the vehicle or in the vicinity of the vehicle, analysing the captured image, detecting if the captured image contains a person, determining at a first time a characteristic associated with the person in the captured image, comparing the characteristic with a predefined threshold value; and in response to the determined parameter surpassing the predefined threshold value, actuating a change of state of the vehicle. The characteristic may comprise temperature.
Patent CA-3135367-A1 (CA)
Inventor: GAO GUANGPING
IPC: C07K14/47
Filed: 2020-04-09
Abstract: Aspects of the disclosure relate to compositions and methods for expressing a Factor H protein (or a variant thereof) in a cell or subject. In some embodiments, the disclosure provides isolated nucleic acids and rAAVs comprising a transgene encoding a Factor H protein variant and one or more regulatory sequences. In some embodiments, compositions described herein are useful for treating subjects having diseases associated with Factor H deficiency.
Patent CA-3137795-A1 (CA)
Title: Efficient production of a containerboard to be used as fluting
Inventor: NORDSTROM FREDRIK
IPC: D21H11/00
Filed: 2020-05-14
Abstract: There is provided a method of producing a containerboard having a geometric SCT index of 37.0-42.0 Nm/g when measured according to ISO 9895:2008, comprising the steps of: - providing a pulp having a Schopper-Riegler (SR) value of 15-19 when measured according to ISO 5267-1:1999, wherein at least 70% by dry weight of the pulp is NSSC pulp; - forming a web from the pulp; - pressing the web in a press section comprising a shoe press, wherein the shoe press comprises a shoe press belt having discontinuous grooves and the line load in the shoe press is in the range of 1400-2000 kN/m; - drying the web from the press section in a drying section to obtain said containerboard.
Patent CA-3139701-A1 (CA)
Inventor: GARZA RAMON
IPC: E21B33/12
Filed: 2020-05-05
Abstract: Un procédé de fonctionnement dans un puits de forage comprend la mise en contact d'un article de fond de trou comprenant un composite d'ester de cyanate avec un fluide de traitement comprenant du carbonate de propylène à une température d'environ 25 °C à environ 300 °C ; et la désintégration de l'article de fond de trou.
Patent CA-3139924-A1 (CA)
Inventor: ZHU XIAOHUA
IPC: A24F40/46
Filed: 2020-05-14
Abstract: Il est décrit un dispositif de chauffage sans contact comprenant un élément céramique chauffant, un composant de support de produit de formation de fumée et un manchon d'étanchéité. Le manchon d'étanchéité enveloppe l'élément céramique chauffant et le composant de support de produit de formation de fumée séparément à l'intérieur. L'élément céramique chauffant comprend un corps chauffant cylindrique et un circuit chauffant pourvu intérieurement d'un canal poreux. Le circuit chauffant est disposé sur le corps chauffant de manière à chauffer l'air passant dans le canal poreux. Le composant de support de produit de formation de fumée comprend un tube céramique pour placer un produit de formation de fumée et une pièce de blocage reliée au tube céramique et adjacente à l'élément céramique chauffant pour limiter la position du produit de formation de fumée. Le dispositif de chauffage sans contact chauffe l'air passant dans l'élément céramique chauffant de façon que le produit de formation de fumée soit chauffé uniformément.
Patent CA-3142959-A1 (CA)
Title: Ramp assembly with raised ramp position
Inventor: SMITH ADAM
IPC: B60P1/43
Filed: 2020-07-01
Abstract: A ramp assembly to accommodate a wheel-chaired passenger to enter or exit a motorized vehicle includes a frame, a ramp movable relative to the frame, a drive block configured to move the ramp relative to the frame, a linkage arm having a first end pivotably coupled to the drive block, a linkage panel pivotably coupled to the linkage arm and a rear end of the ramp, and an upper roller pivotably coupled to the linkage panel for rotation about a pivot axis of the linkage panel to facilitate rotation of the ramp relative to the frame.
Patent CA-3143999-A1 (CA)
Title: Moveable seal point packing system
Inventor: SHUCK CHARLES BENJAMIN
IPC: F16J15/18
Filed: 2020-06-18
Abstract: A packing assembly providing a seal point configurable at multiple locations. The packing assembly includes a soft bed having at least one energizing ring and at least one seal ring. The assembly includes a spacer ring sealable with the at least one energizing ring. The assembly further includes at 1=least one adapter ring abutting either end of the soft bed to provide two seal locations relative to the spacer ring.
Patent CA-3146029-A1 (CA)
Title: Food compositions for weight management
Inventor: SAMUEL TINU MARY
IPC: A23L33/15
Filed: 2020-07-08
Abstract: The present invention concerns a food composition comprising at least one of fiber, beta-carotene, folate, magnesium, zinc, vitamin C, and thiamin, for use in assisting in post-partum weight management.
Patent CA-3149790-A1 (CA)
Title: Systems and methods for coordination of asset procurement transactions
Inventor: DAVIDSON RYAN P
IPC: G06Q30/06
Filed: 2020-09-08
Abstract: Systems and methods for automated coordination of asset procurement transactions are disclosed. Systems and methods include receiving transaction information for the asset procurement transaction. The transaction information identifies a type of asset procurement transaction, an asset being procured, and parties to the transaction. The method further includes determining, based on status information received while the asset procurement is pending, a current step of the transaction, a next step of the transaction, and an action required to advance the transaction to the next step. The method further includes providing a user interface to a party to the transaction via a computing device of the party and providing, via the user interface, a prompt enabling the party to perform the action using the user interface.
Patent CA-3151770-A1 (CA)
Title: Schemas posologiques pour le traitement de patients presentant un carcinome localement avance des cellules squameuses
Inventor: BRIENZA SILVANO
IPC: A61K31/282
Filed: 2020-09-25
Abstract: La présente invention concerne des procédés d'administration d'inhibiteurs de protéine d'apoptose ("IAP"), ou leurs sels pharmaceutiquement acceptables, pour le traitement d'un patient humain présentant un carcinome localement avancé des cellules squameuses.
Patent CA-3157299-A1 (CA)
Title: Anti-vermin apparatus for protecting suspended lines
Inventor: CROWLE WILLIAM E
IPC: A01M29/30
Filed: 2022-05-03
Abstract: An anti-vermin apparatus for protecting suspended, overhead lines. The apparatus includes a line cover with an elongate junction. Two panels are connected to the junction and depending downwards from it. The panels are angled away from each other.  The junction has a line mounting wall disposed towards a line. The wall is in moveable contact with the line and permits side-to-side rocking of the line cover. A ridge is connected to the junction and extends along its length. The ridge is located on the opposite side of the line mounting wall. The panels and the ridge are sized and shaped to balance the line cover on the line so that if a vermin applies force to one or both of the panels, it causes rotation of the line cover on the line a sufficient amount so that the vermin falls.
Patent CA-3157864-A1 (CA)
Inventor: CRYSTAL RONALD G
IPC: A61P25/28
Filed: 2020-10-16
Abstract: L'invention concerne des compositions et des procédés pour prévenir, inhiber ou traiter une maladie ou un trouble associé à l'expression de APOE4 chez un mammifère.
Patent CA-3158030-A1 (CA)
Inventor: WU DI
IPC: G01C25/00
Filed: 2022-05-09
Abstract: A view-based method for controlling the driving of agricultural machinery includes collecting ground information from images; identifying a target operation area according to the ground image information; determining a navigation route for the agricultural machinery within the target operation area; and determining whether the navigation route is reliable; detecting manual driving signal of the user and allowing manual driving of the agricultural machinery according to the manual driving signal if the navigation route is not reliable; and determining driving adjustment parameters for the navigation route and current driving attitude if the navigation route is found reliable. A system for driving agricultural machinery, a device applying the method, and a non-volatile storage medium are also disclosed.
Patent CA-3158560-A1 (CA)
Title: Measuring fluid flow associated with a dialysis machine
Inventor: PLAHEY KULWINDER S
IPC: A61M1/28
Filed: 2020-11-02
Abstract: A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a control unit configured to monitor an amount of fluid withdrawn from a heater bag line during a PD treatment. A processor in the control unit is configured to operate a first pump to draw fluid into a first pump chamber and measure a first fluid volume in the first pump chamber. The processor is further configured to operate the first pump and a second pump to transfer fluid from the first pump chamber to a second pump chamber, measure a second fluid volume in the second pump chamber, and determine a measured fluid volume for a single pump cycle based on the first fluid volume and the second fluid volume. The first fluid volume is correlated to the second fluid volume and, therefore, the multiple independent measurements increase an accuracy of the fluid volume measurement.
Patent CA-3159556-A1 (CA)
Inventor: SCHMIDT JORDAN
IPC: A47G21/14
Filed: 2020-10-28
Abstract: Un support de couteaux verrouillable (100, 300) utilise des systèmes de verrouillage mécaniques ou électroniques pour fixer les couteaux dans le support. Le système de verrouillage électronique comprend la mise en oeuvre d'un ou de plusieurs électroaimants (208, 308) dans le support. L'utilisateur peut ensuite verrouiller ou déverrouiller sélectivement les couteaux dans le support par activation ou désactivation de l'électroaimant, respectivement. Dans d'autres modes de réalisation, le système de verrouillage mécanique peut utiliser des clés magnétiques pour déverrouiller le système de verrouillage mécanique.
Patent CA-3162793-A1 (CA)
Title: Co-agonistes d'olefine agrafes des recepteurs du glucagon et du glp-1
Inventor: BIANCHI ELISABETTA
IPC: C07K14/605
Filed: 2020-12-18
Abstract: Les peptides agrafés selon la présente invention, et des sels pharmaceutiquement acceptables de ceux-ci, sont des co-agonistes des récepteurs du glucagon et du GLP-1, et peuvent être utiles dans le traitement, la prévention et la suppression de maladies médiées par le récepteur du glucagon et le récepteur du GLP-1, comportant, entre autres, des troubles métaboliques tels que le diabète, la stéatose hépatique non alcoolique (NAFLD), la stéatohépatite non alcoolique (NASH) et l'obésité.