Patent SG-11201907402S-A (SG)
Title: Population-based immunogenic peptide identification platform
Inventor: LISZIEWICZ JULIANNA
IPC: G01N33/50
Filed: 2018-03-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 07 September 2018 (07.09.2018) WIPO I PCT oimitia OH oI0IIIOH011101OIH010mmo oimIE (10) International Publication Number WO 2018/158457 Al (51) International Patent Classification: EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, G01N 33/50 (2006.01) A61K 39/00 (2006.01) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, G01N 33/569 (2006.01) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, (21) International Application Number: KM, ML, MR, NE, SN, TD, TG). (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 17159243.9 17159242.1 1703809.2 PCT/EP2018/055232 02 March 2018 (02.03.2018) English English 03 March 2017 (03.03.2017) EP 03 March 2017 (03.03.2017) EP 09 March 2017 (09.03.2017) GB Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) (71) Applicant: TREOS BIO ZRT [HU/HU]; Viola utca 2, 8200 Veszprem (HU). (72) Inventors: LISZIEWICZ, Julianna; Szorosi ut 13, 8220 Balatonalmadi (HU). MOLNAR, Levente; Kossuth Lajos u. 20., 2363 Felsopakony (HU). TOKE, Eniko, R.; Kos- suth Lajos u. 20., 2363 Felsopakony (HU). TOTH, Jozsef; Ujkut u. 72, 9012 Gyor (HU). LORINCZ, Orsolya; At- tila u. 27, fszt/13, 1047 Budapest (HU). CSISZOVSZKI, Zsolt; Bikszadi u. 12/A, 4/9, 1119 Budapest (HU). SOM- OGYI, Eszter; Borgazda u. 3, 8220 Balatonalmadi (HU). PANTYA, Katalin; Ulloi ut 16/b 2.em. 9/b, 1085 Budapest (HU). MEGYESI, Monika; Tancsics Mihaly u. 63, 3441 Mezokeresztes (HU). (74) Agent: KIMBLIN, Nicola; 14 South Square, Gray's Inn, London Greater London WC1R 5JJ (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (54) Title: POPULATION-BASED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM (57) : The disclosurerelates to methods of identifying fragments of a polypeptide that are immunogenic for a specific hu- man subject, methods of preparing pharmaceutical compositions comprising such polypeptide fragments, pharmaceutical compositions comprising such polypeptide fragments, and methods of treatment using such compositions. The methods comprise identifying a frag- ment of the polypeptide that binds to multiple HLA of individual subjects.