baber/WOPTO huggingface dataset:
Patent CA-2432624-A1 (CA)
Title: Sensor with integrated lancet
Inventor: CHARLTON STEVEN C
IPC: A61B5/00
Filed: 2003-06-17
Abstract: A fluid collection apparatus adapted to test a concentration of an analyte in a fluid, in-cluding a lid and a base. Further included is a spacer disposed between the lid and the base. The spacer forms a capillary channel, which has an opening and is designed to collect the fluid. The capillary channel includes a reagent that reacts with the fluid to produce a measur-able reaction. The reaction will provide a measurable indication of the concentration of the analyte in the fluid. Coupled to the lid is a lance that is moveable to the base and is moveable to a position adjacent the opening of the capillary channel.
Patent CA-2435888-A1 (CA)
Title: Method of preparing biological materials and preparation produced using same
Inventor: KO SAI-YING THOMAS
IPC: A61K35/74
Filed: 2002-01-24
Abstract: Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a coating liquid comprising at least one active, a sugar polymer and a water soluble/miscible solvent; (ii) providing a quantity of microparticles comprising at least water soluble gel forming solid particles; (iii) fluidizing said quantity of microparticles within a processing chamber of a of a suitable apparatus to form a fluidized bed of said microparticles; (iv) spraying said coating liquid onto said fluidized bed from beneath the fluidized bed to coat said microparticles therewith under saturated moisture conditions; and (vi) allowing coated microparticles to dry, are described. Also described are compositions and uses.
Patent CA-2437534-A1 (CA)
Title: Use of a silicone surfactant in polishing compositions
Inventor: BARAN JIMMIE R JR
IPC: C09G1/16
Filed: 2002-02-05
Abstract: An aqueous polishing composition comprising a film forming polymer and an ionic silicone surfactant is described. The polish can be applied to a variety of substrates, particularly to floor surfaces. The coatings are smooth and soil resistant. The polish composition performs as well as state-of-the-art formulations containing a fluorocarbon surfactant.
Patent CA-2441151-A1 (CA)
Inventor: SENOO YASUMASA
IPC: B29C44/12
Filed: 2003-01-06
Abstract: A cushion body of a seat cushion easily reinforced at a low cost, a method of manufacturing the cushion body, and a foam molding device used for the manufacturing method, the cushion body (10) having the front surface and both side surfaces formed in a shape generally matching the shape of the seat cushion ranging from the front surface to both side surfaces thereof comprising a foam body (11) formed of cold urethane foam formed in a shape generally matching the profile of the cushion body (10), permeable materials (12) fixed to the foam body (11) integrally with each other, and impregnated layers (13) fixing the permeable materials (12) to the foam material (11) integrally with each other to reinforce the portions of the cushion body (10) where the permeable materials (12) are fixed to the foam body (11) integrally with each other, wherein the thicknesses of the impregnated layers (13) are such that can provide a specified reinforcement strength to the portions of the cushion body (10) where the permeable materials (12) are fixed to the foam body (11) integrally with each other.
Patent CA-2447812-A1 (CA)
Inventor: HUEBNER KENNETH L
IPC: B21D39/04
Filed: 2002-06-20
Abstract: L'invention concerne un appareil portable (10) permettant de sertir un raccord de tuyau (95) à l'extrémité d'un tuyau (97). Ledit appareil comprend un logement unitaire (20) servant à fixer et à retenir les composants utilisés au cours du sertissage, le logement (20) comprenant un axe longitudinal et quatre côtés entourant une section centrale ouverte (25). Un des côtés constitue une base (21) située à une extrémité de la section centrale ouverte (25) et il est perpendiculaire à l'axe longitudinal, une ouverture de réception (29) s'y étendant pour loger les composants. Un autre des côtés constitue une portion supérieure (22), il est également perpendiculaire à l'axe longitudinal et il est situé sur l'extrémité opposée de la section centrale ouverte (25) provenant de la base (21), ce qui permet de fixer un cylindre (40), un piston (45) et un dispositif pousseur (50). Les deux côtés restants (23, 24) sont parallèles à l'axe longitudinal et sont situés sur des côtés opposés de la section centrale ouverte (25), la surface externe de chacun de ces deux côtés (23, 24) présentant des trous de fixation (34).
Patent CA-2449754-A1 (CA)
Inventor: MITRA SUMITA B
IPC: A61K31/4743
Filed: 2002-06-14
Abstract: The disclosure provides methods for the treatment and prevention of periodontal disease. In preferred embodiments, the invention provides for local treatment of periodontal tissues with a pharmaceutical composition including an immune response modifier (IRM) selected from the group of immun e response modifiers comprising imidazoquinoline amines, imidazopyridine amine s, 6,7-fused cycloalkylimidazopyridine amines, imidazonaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines and 1,2-bridged imidazoquinoline amines.
Patent CA-2450108-A1 (CA)
Title: Self-contained integrated welder/generator and compressor
Inventor: SILVESTRO NINO
IPC: B23K9/10
Filed: 2003-11-17
Abstract: An integrated welder, generator and compressor unit that includes a housing that at least partially contains components of a welder, generator and compressor. An engine, an electric current generator, and an air compressor are at least partially mounted in the housing. The electric current generator is at least partially connected to the engine to he at least partially driven thereby. A drive connector at least partially connects the air compressor to the engine and/or electric current generator. The drive connector includes a gear box that has at least one gear.
Patent CA-2451509-A1 (CA)
Inventor: VALENTINE PETER L
IPC: F01P7/16
Filed: 2002-05-16
Abstract: L'invention concerne un appareil de refroidissement (10) et un procédé conçus pour un moteur thermique turbocompressé (12). L'air de combustion s'échappant d'un turbocompresseur (18) passe au-dessus d'un refroidisseur intermédiaire air-eau (40), puis au-dessus d'un refroidisseur intermédiaire air-air (42) aux fins d'un échange thermique avec le liquide de refroidissement et l'air ambiant 32 respectivement. Lors des périodes de basse température de l'air ambiant, l'air de combustion peut être dirigé à travers un tuyau de dérivation (80) entourant le refroidisseur intermédiaire air-air, puis réchauffé par le liquide de refroidissement dans le refroidisseur intermédiaire air-eau. Un ventilateur (44) à plusieurs vitesses et/ou des volets amovibles (48) peuvent être utilisés pour commander le débit d'air ambiant traversant le refroidisseur intermédiaire air-air. Un tuyau de refroidissement (68) alimente en air ambiant le moteur (46) du ventilateur pendant les périodes de fonctionnement lorsque le débit d'air ambiant au-dessus de l'échangeur thermique air-air est limité par lesdits volets. Le liquide de refroidissement s'échappant d'un sous-refroidisseur (28) a la température la plus basse dans le système; il est alors dirigé vers un refroidisseur d'huile de graisse (34) destiné au refroidissement du lubrifiant du moteur.
Patent CA-2451577-A1 (CA)
Title: Gene delivery vectors with cell type specificity for mesenchymal stem cells
Inventor: VOGELS RONALD
IPC: A01N63/00
Filed: 2002-07-05
Abstract: The present invention provides novel methods and means for delivering a heterologous nucleic acid of interest to mesenchymal stem cells by providing recombinant adenoviral vectors provided with, or having a natural tropism fo r mesenchymal stem cells, typically in combination with a reduced tropism for other kinds of cells, in particular liver cells. The invention also provides mesenchymal stem cells provided with a heterologous nucleic acid through the use of a recombinant adenoviral vector according to the invention, and the u se of such mesenchymal stem cells for the preparation of medicaments for the treatment of multiple sclerosis, rheumatoid arthritis, angiogenesis and bone related disorders, for instance in treatments that involve bone (re)generati on.
Patent CA-2454517-A1 (CA)
Title: Nouveaux composes
Inventor: THONNARD JOELLE
IPC: C07K14/285
Filed: 2002-07-18
Abstract: L'invention concerne des polypeptides BASB230 et des polynucléotides codant les polypeptides BASB230 ainsi que des procédés de production de ces polypeptides par des techniques recombinantes. Font également l'objet de cette invention leurs utilisations diagnostique, prophylactique et thérapeutique.
Patent CA-2455447-A1 (CA)
Title: Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
Inventor: MCSWIGGEN JAMES
IPC: C07H21/02
Filed: 2003-02-20
Abstract: The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications.  Specifically, the invention relates to small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against target nucleic acid sequences. The small nucleic acid molecules are useful in the treatment of any disease or condition that responds to modulation of gene expression or activity in a cell, tissue, or organism.
Patent CA-2455542-A1 (CA)
Inventor: GIBELIN NATHALIE
IPC: C07K14/435
Filed: 2002-07-12
Abstract: The invention concerns mutated photoproteins derived from isolated jellyfish photoproteins, said mutated photoproteins being characterised in that they exhibit a thermostability higher than that of the photoproteins from which they are derived, and are called thermostable mutated photoproteins, and/or a luminescence duration longer than that of the photoproteins from which they are derived, and are called persistent mutated photoproteins. The invention also concerns the use of said mutated photoproteins in methods for detecting in vitro molecules in a biological sample, methods for detecting compounds with enzymatic activity in a biological sample, or methods for detecting intracellular calcium variations.
Patent CA-2455893-A1 (CA)
Inventor: SANFORD MELANIE S
IPC: B01J31/18
Filed: 2002-06-14
Abstract: The present invention relates to novel hexacoordinated metathesis catalysts and to methods for making and using the same. The inventive catalysts are of the formula wherein: M is ruthenium or osmium; X and XI are the same or different and are each independently an anionic ligand; L, L 1' and L 2 are the same or different and are each independently a neutral electron donor ligand; and, R and R 1 are each independently hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, aryl, C1-C20carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthio, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl and silyl. Optionally, each of the R or R 1 substituent group may be substituted with one or more moieties selected from the group consisting of C1-C10 alkyl, C1-C10 alkoxy, and aryl which in turn may each be further substituted with one or more groups selected from a halogen, a C1-C5 alkyl, C1-C5 alkoxy, and phenyl. Moreover, any of the catalyst ligands may further include one or more functional groups. Examples of suitable functional groups include but are not limited to: hydroxyl, thio l, thioether, ketone, aldehyde, ester, ether, amine, imine, amide, nitro, carboxylic acid, disulfide, carbonate, isocyanate, carbodiimide, carboalkoxy , carbamate, halogen, alcohol, sulfonic acid, phosphine, imide, acetal, ketal, boronate, cyano, cyanohydrin, hydrazine, enamine, sulfone, sulfide, and sulfenyl. In certain embodiments, at least one of L, L l' and L 2 is an N- heterocyclic carbene ligand.
Patent CA-2455983-A1 (CA)
Title: Preservative systems and their use in cosmetic preparations
Inventor: SEGUER BONAVENTURA JOAN
IPC: A01N43/80
Filed: 2001-08-09
Abstract: The invention relates to preservative systems which are particularly suitable in cosmetic and dermatological preparations. The preservative system which comprises a cationic surfactant, derived from the condensation of fatty acids and esterified dibasic amino acids, having the formula (I) where: X-is Br-, C1-, or HSO 4 R1: is a straight alkyl chain from an acid or saturated fatty hydroxy acid from 8 to 14 atoms of carbon bonded to the .alpha.-amino acid group through amidic bond. R2: is a straight or branched alkyl chain from 1 to 18 carbon atoms or aromatic. R3: is: (II) where n can be from 0 to 4, is combined with at least one other ionic or non-ionic preservative agent, whereby the combination displays a synergetic activity. A preservative system, wherein the cationic surfactant preservative derived from the condensation of fatty acids and esterified dibasic amino acid is LAE is particularly preferred. The other ionic or non ionic preservative agent is preferably at least one component selected from the group consisting of 2-bromo-2-nitro-1,3-propanediol (bronopol), parbens, imidazolidinyl urea, phenoxyethanol, DMDM  hydantoin, 2-methyl-5-chloro-3,4-isothiazolinone/2-methyl-3,4-isothiazolinone and quaternium-15.
Patent CA-2458692-A1 (CA)
Title: Protecting an inert anode from thermal shock
Inventor: BURG JAMES T
IPC: C25C3/10
Filed: 2004-02-25
Abstract: A method for protecting anode assemblies in an electrolytic cell from thermal shock is disclosed. The method generally involves applying a thermal insulating layer (8, 16) to the anode (2) prior to preheating the anode assembly in a furnace, where the layer (8, 16) protects the anode (2) from thermal shock during transfer from the preheat furnace to the electrolytic cell. In a preferred embodiment the anode (2) is attached to a castable plate (4) that is also protected from thermal shock by an insulating layer.
Patent CA-2459892-A1 (CA)
Title: Redundant prime mover system
Inventor: POTEET DARRELL
IPC: B60L50/10
Filed: 2002-09-05
Abstract: The present invention provides a redundant prime mover system to drive a machine having an engine coupled to the machine, and a motor/generator coupled to the machine and an electrical network connection. The engine and the motor/generator have three or four operating modes. The first operating mode drives the machine with the engine.  The second operating mode drives the machine with the motor/generator. The third operating mode drives the machine and the motor/generator with the engine such that the motor/generator generates electricity for delivery to the electrical network connection.  Alternatively, the third operating mode drives the machine with both the engine and the motor/generator. This alternate operating mode can also be included as a fourth operating mode.
Patent CA-2460286-A1 (CA)
Inventor: BUNGARTEN JOERG
IPC: C09D7/80
Filed: 2004-03-08
Abstract: Novel paint formulations are described containing hectorite and phosphonate additives. The paint formulations are useful for a wide variety of paints and coatings particularly those are applied by spraying and are particularly useful for metallic coating formulations applied to automobiles.
Patent CA-2463819-A1 (CA)
Title: Device and process for generating carbon dioxide snow
Inventor: HO YEU-CHAUN SIMON
IPC: C01B32/55
Filed: 2002-10-09
Abstract: A device useful for delivering carbon dioxide snow comprises a supply conduit (1) for providing a flow of pressurized carbon dioxide, a plurality of tubes (3) disposed side by side, each tube (3) having a constant cross-sectional configuration and area throughout its length, each tube (3) having a first end (4) the peripheral edges of which are sealed to the outside of the conduit wall and a second end (5) which is open to the ambient atmosphere, and a plurality of apertures (7) for carbon dioxide to flow through the conduit wall and expand to solids and vapor, there being at least one aperture (7) communicating with the interior of each of said plurality of tubes (3).
Patent CA-2463876-A1 (CA)
Title: Implosion resistant containers
Inventor: BEZEK EDWARD ANTHONY
IPC: B65D90/02
Filed: 2002-10-25
Abstract: The present invention overcomes many of the shortcomings inherent in previous containers for packaging potato chips, corn based chips, cookies or the like.  The improved implosion-resistant container of the present invention utilizes a collection of stress dissipating mechanisms (10) that counteract the forces causing thermo-plastic container deformation, implosion and loss of seal integrity. This collection of stress dissipating mechanisms, employed collectively or separately, allows a container for storing fragile food products to be fashioned as a relatively lightweight, thin-walled blow molded thermo-plastic container that is capable of adapting to changing environmental conditions while maintaining its visual aesthetic appearance.
Patent CA-2463963-A1 (CA)
Title: Procede de fabrication de fils supraconducteurs a base de mgb2 comprenant un traitement thermique
Inventor: MALAGOLI ANDREA
IPC: H01B12/10
Filed: 2002-10-16
Abstract: L'invention concerne un procédé de fabrication de fils supraconducteurs à base de MgB¿2?. Ce procédé comprend les étapes consistant à produire un fil cylindrique comprenant une âme de MgB¿2? entourée d'un revêtement métallique, cette âme possédant une structure du réseau cristallin formée de grains du composé MgB¿2?, à laminer ce fil afin de produire un conducteur en forme de bande, puis à traiter thermiquement ce conducteur en le chauffant à une température comprise entre 800 et 870 ·C. Cette dernière étape permet d'augmenter la liaison entre les grains de MgB¿2? tout en retenant les défauts structurels produits lors de l'étape de laminage, ce qui permet de produire un fil supraconducteur possédant une plus grande capacité de transmission de courant.
Patent CA-2466162-A1 (CA)
Title: Dual input ac/dc/battery operated power supply
Inventor: MACDONALD GILBERT
IPC: H02M7/12
Filed: 2002-10-30
Abstract: A dual input battery assisted power converter (10) which provides a continuous, regulated DC voltage output to a user-connected mobile device, such as, a laptop computer or a cell phone, for example. The power converter (10) comprises a power supply circuit (12) and a separate, detachable power storage circuit comprising a battery pack (14) having a re-chargeable battery (36). The power supply (12) is adapted to deliver a pair of regulated DC  output voltages, of opposite voltage potentials, to a pair of respective output terminals. Preferably these output voltages are derived from two external input voltages: an AC input voltage and a DC input voltage.  Advantageously, if both of the external input voltages are temporarily removed, the battery pack (14) will advantageously serve as a substitute DC  input power source, thereby allowing the power supply (12) to deliver the same regulated DC output voltage to the user-connected mobile device without interruption. Moreover, once either of the external input voltages are again re-established, the battery pack (14) automatically taps the output terminal of the power supply (12) at a node to recharge the battery pack (14).
Patent CA-2466360-A1 (CA)
Inventor: YAMAGUCHI TAKASHI
IPC: B60N2/68
Filed: 2002-09-18
Abstract: A tension structure for forming the seat back of a car seat, comprising coiled springs (3a), (3b), (4a), and (4b) as tension members across the upper parts and intermediate parts of the side frame parts (11) and (12) of a seat back frame (1) and the vertical rail bars (20) and (21) of a tension assembly (2), wherein straight wires (5a) and (5b) having one wire ends fixed around the axes of the vertical rail bars (20) and (21) and the other wire ends fixedly inserted into the retaining rings (14) and (15) of the side frame parts (11) and (12) are installed on the lower parts of the side frame parts (11) and (12), whereby a seating posture can be stabilized by increasing the support pressure of a waste part supported by the tension assembly (2) with the straight wires (5a) and (5b).
Patent CA-2466616-A1 (CA)
Title: Aqueous dye solutions
Inventor: HENEGHAN MICHAEL
IPC: C09B67/44
Filed: 2003-01-21
Abstract: The present invention relates storage stable aqueous dye solutions comprisin g a) 5 to 30% by weight of a dye of the Formula (1) in which K is a residue of a coupling component of the acetoacetanilide, pyridone, pyrazolone or pyrimidi ne series and M is hydrogen, an alkali metal or alkaline earth metal, ammonium or alkyl ammonium, b) 0.05 to 5% by weight of one or more compounds of the Formula (2) in which A represents -NR1R2, -NHCOR1,-CN, halogen, -NO2-OH, -OR 1, hydrogen, C1,-C4alkyl, C2- C4alkenyl, C2-C4alkynil, -CO2M, - CO2R1 or -CONR1 R2, wherein R1 and R2 each, independently of one another, represent hydrogen or C1-C4alkyl and M is as previously defined, or a residue of the Formula (3 ); X represents O, S or NR1, R1, being as previously defined; Y represents N or CR1, R1 being as previously defined and P, Q and R each, independently of on e another, represent hydrogen, C1-C4alkyl,- SO3M, -PO3M, -CO2M, -OH, -NO2 or COR1, M and R'1 being as previously defined, c) an organic or an inorganic base or mixtures thereof, d) if desired, further additives and e) water, a process for their preparation and the use thereof for the dyeing, in particular of paper.
Patent CA-2467890-A1 (CA)
Title: Process for the preparation of ethylene copolymers using meso- and rac-stereoisomeric mixtures of metallocenes
Inventor: PROVERA ROBERTO
IPC: C08F210/16
Filed: 2002-11-18
Abstract: A process is described for the preparation of ethylene copolymers having a wide molecular weight distribution, characterized in that it is carried out in the presence of meso- and rac- stereoisomeric mixtures of metallocene compounds having general formula (I), wherein A' and A'', the same or different, are a radical of the .eta.5-tetrahydroindenyl type (Ia).
Patent CA-2471787-A1 (CA)
Inventor: CASTELLANO THOMAS
IPC: A61M1/36
Filed: 2004-06-22
Abstract: A system for facilitating the insertion of a medical device into a patient, comprises a flexible sheath and an air trap chamber coupled thereto. The air trap chamber includes a device insertion opening and an exit opening which allow the distal end of a medical device to pass through the chamber before it enters the sheath. The chamber also includes a gas removal port opening for preventing air from entering the sheath by removing air from the chamber.
Patent CA-2472186-A1 (CA)
Inventor: MILAN SANDRA
IPC: C07K16/32
Filed: 2003-01-18
Abstract: La présente invention concerne des méthodes de traitement d'un individu atteint d'un cancer qui se caractérise par la surexpression de la protéine réceptrice HER2, lesdites méthodes comprenant l'utilisation d'une combinaison d'interleukine 2 (IL-2) ou d'un variant biologiquement actif de cette dernière et d'au moins un anticorps anti-HER2 ou d'un fragment de liaison à l'antigène de ce dernier. Ces agents thérapeutiques sont administrés sous forme de deux compositions pharmaceutiques séparées, une première composition qui contient IL-2 (ou un variant de cette dernière) et qui est administrée suivant un schéma posologique d'IL-2 constant ou suivant un schéma posologique d'IL-2 à deux niveaux, et une deuxième composition qui contient au moins un anticorps anti-HER2 (ou un fragment de ce dernier) et qui est administrée suivant un schéma posologique hebdomadaire ou bien une semaine sur deux, sur trois ou sur quatre. L'administration de ces deux agents potentialise l'efficacité de l'anticorps anti-HER2 utilisé seul, ce qui produit une réponse thérapeutique positive qui est meilleure que celle qu'on observe lorsqu'on utilise cet agent thérapeutique seul.