baber/WOPTO huggingface dataset:
Patent NZ-749214-A (NZ)
Title: Multisubstituted aromatic compounds as serine protease inhibitors
Inventor: SHORT KEVIN
IPC: A61K31/4412
Filed: 2014-03-17
Abstract: There are provided uses of compounds having a structure according to Formula (V) or pharmaceutically acceptable salt, ester, or solvate thereof, or a pharmaceutical composition comprising said compound, for the manufacture of a medicament for the treatment of a thrombotic disorder, a kallikrein-related disorder, or a disease or disorder responsive to inhibition of thrombin and/or kallikrein in a subject, wherein the kallikrein-related disorder comprises at least one of an ophthalmic disease, a thrombotic disease, a fibrinolytic disease, a type of cancer, an inflammatory condition, or a dermatological condition. Representative compounds of formula (V) include compounds such as 3-(5-{ [(5-chlorothiophen-2-yl)methyl]amino} -1-[(furan-3-yl)carbonyl]-1H-pyrazol-3-yl)-1,2-dihydropyridin-2-one, 3-(5-{ [(5-chlorothiophen-2-yl)methyl]amino} -1-[(furan-3-yl)carbonyl]-1H-pyrazol-3-yl)-1-methyl-1,2-dihydropyridin-2-one, 3-(5-{ [(5-chlorothiophen-2-yl)methyl]amino} -1-[(furan-3-yl)carbonyl]-1H-pyrazol-3-yl)-1-(pyridin-2-ylmethyl)-1,2-dihydropyridin-2-one, 3-(5-{ [(5-chlorothiophen-2-yl)methyl]amino} -1-[(furan-3-yl)carbonyl]-1H-pyrazol-3-yl)-1-(furan-2-ylmethyl)-1,2-dihydropyridin-2-one, 3-(5-{ [(5-chlorothiophen-2-yl)methyl]amino} -1-[(2-methoxyphenyl)carbonyl]-1H-pyrazol-3-yl)-1,2-dihydropyridin-2-one and the like.
Patent NZ-795105-A (NZ)
Title: Oil-in-water type emulsion composition, and method for producing said oil-in-water type emulsion composition
Inventor: HANASAKI MINAKO
IPC: A23D7/005
Filed: 2017-12-08
Abstract: The object of the present invention is to provide an emulsion composition that maintains emulsion stability even after high temperature process such as sterilization (heat resistance), shows a small change in particle size distribution between before and after heating, and maintains emulsion stability even under conditions where transformation of an oil phase component (for example, solidification or crystallization of the oil phase component due to temperature drop, or melting of the oil phase component due to temperature rise) occurs (temperature drop resistance), wherein the composition is easily handled during the production process. The object is solved by an oil-in-water emulsion composition containing solid particles, a predefined surfactant, an oil phase component, and an aqueous phase component, wherein the oil phase component includes a predefined oil component and the solid particles are distributed along the interface between the oil phase component and the aqueous phase component.
Patent PT-100460-A (PT)
Inventor: MCLAUCHLAN JOHN
IPC: C07D405/08
Filed: 1992-05-06
Abstract: In addition to virions, herpesvirus-infected cells produce non-infectious particles, termed L-particles, which consist of tegument surrounded by envelope but lack the nucleocapsid. L-particles of a herpesvirus can be prepared substantially free of infectious virions, e.g. by allowing an appropriate temperature-sensitive mutant to replicate at its non-permissive temperature, and such L-particles are useful as a component of a vaccine against the herpesvirus. They can also be prepared to contain a foreign protein or peptide, by use of a recombinant herpesvirus.
Patent PT-103973-A (PT)
Title: Sistema termo-regulatório com multi-controlo de um maqnequim higro-térmico com transpiração natural através de material poroso.
Inventor: CONCEICAO EUSEBIO ZEFERINO ENC
IPC: G09B23/06
Filed: 2008-02-21
Abstract: A PRESENTE INVENÇÃO TRATA DE UM SISTEMA TERMO - REGULATÓRIO DE UM MANEQUIM CONSTRUÍDO A PARTIR DE OITO SISTEMAS INDEPENDENTES DE CIRCULAÇÃO, AQUECIMENTO, CONTROLO E TRANSPIRAÇÃO. O MANEQUIM É DESENVOLVIDO ATRAVÉS DE UMA CASCA DE MATERIAL POROSO (TERRACOTA) COM ALGUNS CENTÍMETROS DE ESPESSURA, DIVIDIDO EM OITO SECÇÕES CHEIAS DE ÁGUA QUENTE TRATADA (A CABEÇA, O TRONCO, OS BRAÇOS, AS COXAS E AS PERNAS/PÉS), E PODE SER UTILIZADO NA AVALIAÇÃO DAS CONDIÇÕES DE BEM-ESTAR HUMANO.A CIRCULAÇÃO NO CORPO É EFECTUADA A PARTIR DE OITO BOMBAS CIRCULADORAS E OITO SISTEMAS DE CONDUTAS PERFURADAS, SIMILAR AO DO SISTEMA CIRCULATÓRIO HUMANO, O AQUECIMENTO É GARANTIDO ATRAVÉS DE OIRO RESISTÊNCIAS ELÉCTRICAS, O CONTROLO É EFECTUADO A PARTIR DE OITO TERMÓSTATOS DIGITAIS E A TRANSPIRAÇÃO UNIFORME É EFECTUADA NATURALMENTE ATRAVÉS DE UM MATERIAL POROSO. O MANEQUIM É IGUALMENTE EQUIPADO COM UM SISTEMA DE RESPIRAÇÃO E UM SISTEMA DE AUDIÇÃO.
Patent PT-104430-A (PT)
Title: Processo e dispositivo de separação electrostática de partículas de idêntica condutividade eléctrica, aplicado à purificação de café em grão
Inventor: DUARTE ANTONIO PAULO CERQUEIRA
IPC: B03C7/00
Filed: 2009-03-10
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM PROCESSO QUE PERMITE A SEPARAÇÃO DOS GRÃOS DE CAFÉ TORREFACCIONADO DOS SEUS PAUS DE MADEIRA CONTAMINANTES ATRAVÉS DA UTILIZAÇÃO DE UM SEPARADOR ELECTROSTÁTICO ROTATIVO. ESTE PROCESSO DE SEPARAÇÃO NÃO ERA ATÉ AQUI EXEQUÍVEL POR MEIOS ELECTROSTÁTICOS, DEVIDO AO FACTO DE AMBAS AS PARTÍCULAS A SEPARAR SEREM NÃO CONDUTORAS E POSSUÍREM ELEVADA GRANULOMETRIA. A PRESENTE INVENÇÃO PERMITE REMOVER OS PAUS CONTAMINANTES ATRAVÉS DO AUMENTO DO TEMPO DE EXPOSIÇÃO DAS PARTÍCULAS AO CAMPO ELECTROSTÁTICO ANTES DA SUA DEPOSIÇÃO NO RÓTOR SEPARADOR (102), GARANTINDO ASSIM A SUA MAIOR ADERÊNCIA À SUPERFÍCIE (103) DO REFERIDO RÓTOR. ESTE EFEITO RESULTA DA ACÇÃO CONJUGADA DA COLOCAÇÃO DE UM ELÉCTRODO IONIZADOR (118) POSICIONADO SOBRE A CALHA TRANSPORTADORA (116), DA POSTERIOR ACÇÃO EXERCIDA SOBRE AS PARTÍCULAS POR UM ELÉCTRODO ESTÁTICO (101) E DO ALINHAMENTO PERPENDICULAR DOS PAUS CONTAMINANTES COM O EIXO DE ROTAÇÃO DO RÓTOR SEPARADOR (102) NO MOMENTO DA SUA DEPOSIÇÃO SOBRE ESTE.
Patent PT-110496-A (PT)
Title: Processo para a obtenção de um corante natural a partir das pétalas de hibiscus sabdariffa l.: extratos para aplicação na indústria.
Inventor: LILLIAN BARROS
IPC: C09B67/00
Filed: 2018-01-08
Abstract: A PRESENTE INVENÇÃO DESCREVE O PROCESSO DE OBTENÇÃO DE UM EXTRATO CORANTE OBTIDO A PARTIR DAS PÉTALAS DE HIBISCUS SABDARIFFA L. COMO UMA ALTERNATIVA COMPETITIVA AOS CORANTES ARTIFICIAIS JÁ EXISTENTES. ESTE PROCESSO É DETENTOR DE INÚMERAS VANTAGENS, COMO: O FACTO DE SER UM MÉTODO DE EXTRAÇÃO SIMPLES COM O USO MODERADO DE SOLVENTES ORGÂNICOS; A OBTENÇÃO DE UM EXTRATO COM ÓTIMA CAPACIDADE CORANTE TORNANDO-O MUITO COMPETITIVO EM RELAÇÃO AOS CORANTES ARTIFICIAIS JÁ EXISTENTES NO MERCADO; E A UTILIZAÇÃO DE UMA MATRIZ ONDE SÃO ABUNDANTES COMPOSTOS QUE, PARA ALÉM DE MANIFESTAREM O SEU PODER CORANTE, TÊM UM POTENCIAL BIOATIVO, VISTO SER UMA MATRIZ RICA EM ANTOCIANINAS (FIG. 1). A OBTENÇÃO DE CORANTES NATURAIS VAI DE ENCONTRO ÀS PREOCUPAÇÕES E NECESSIDADES DE VÁRIOS SECTORES INDUSTRIAIS, NOMEADAMENTE A SUBSTITUIÇÃO DOS CORANTES ARTIFICIAIS EXISTENTES COM DIVERSOS PROBLEMAS ASSOCIADOS. O CORANTE OBTIDO DETÉM UM ENORME POTENCIAL DE APLICAÇÃO EM VÁRIAS VERTENTES DO SECTOR INDUSTRIAL.
Patent RU-94011631-A (RU)
Inventor: KLAUS DEBBELING
IPC: F23R3/58
Filed: 1994-04-07
Abstract: FIELD: thermal engineering. SUBSTANCE: double-cone premixing burner has two hollow conical, relatively offset central shafts one inserted in other in direction of medium flow. Adjacent walls of both media form longitudinal tangential slits to pass air for burning. Walls are provided with gas vents spaced longitudinally. Air is conveyed through tangential slits by means of swirlers some of which are placed close to each other along slit. Fuel is supplied to slits directly around swirlers. Novel static mixer in the form of three-dimensional swirlers provides for creating longitudinal swirls within inlet slit without recirculation regions. EFFECT: provision for producing extremely short mixing sections at burner inlet with low head loss.
Patent RU-94029135-A (RU)
Inventor: SERENKOV N K
IPC: A23B9/08
Filed: 1994-08-03
Abstract: FIELD: agricultural engineering. SUBSTANCE: heating up of ecologically pure air is carried out at its compression in high-pressure centrifugal compressor. New feature of the construction of grain dryer chamber is in mounting the upper cover with perforation, and in installing the perforated members in upper part of lateral walls of chamber in front of which regulated gate is set up. It shuts off air escape upward during grain pneumatic discharge. Reversible system guiding the regulated part of hot air to the input of compressor in the form of ejecting device is mounted in forcing air duct. EFFECT: simpler design, smaller dimensions and more mobility of grain dryer operating in ecologically pure air.
Patent RU-94030603-A (RU)
Inventor: RASKURATOV JU V
IPC: A61P15/04
Filed: 1994-08-17
Abstract: FIELD: medicine. SUBSTANCE: method involves substituting Platyphyllinum for Amitriptyline with Ethymysol in glucose to be additionally intravenously administered, having concurrently spasmolytic properties and sedative, thymoleptic, psychoenergetic activity. Amitriptyline in the amount of 25 mg and potassium orotate 1000 mg are administered per os, 2% Promedol solution 1.0 ml (20 mg) is administered subcutaneously and 1.5% Ethymysol solution (3 ml) in 5% glucose solution - 200 ml is administered intravenously at the rate of 40 drops per min. The cervix of the uterine being insufficiently mature to the time the labor begins, the treatment complex is to be complemented with intramuscular administration of estrogens at a dose of 300 units per 1 kg of body mass of a woman in childbirth. EFFECT: improved delivery control; stimulated fetoplacental complex; stimulated fetus adaptation capacity.
Patent RU-94031910-A (RU)
Inventor: USTJUZHANINA I JU
IPC: C12P1/00
Filed: 1994-08-31
Abstract: FIELD: medicine, antibiotics. SUBSTANCE: the end product is isolated by dissolving the technical phenoxymethylpenicillin-acid with organic solvent mixing with water followed by crystallization of phenoxymethylpenicillin-acid from an aqueous-organic medium. Method eliminates stages causing antibiotic loss (double suspending technical phenoxymethylpenicillin-acid in butyl acetate, reextraction of antibiotic with potassium acetate aqueous solution and antibiotic potassium salt desalting). EFFECT: increased yield, enhanced quality, improved ecology, decreased net cost.
Patent RU-94039483-A (RU)
Inventor: EGOROV G A
IPC: F01B1/06
Filed: 1994-10-10
Abstract: FIELD: mechanical engineering. SUBSTANCE: motor is operated by compressed air which is sucked away from the crankcase of an engine by a compressor mounted on the engine shaft. The air is then compressed and again fed to cylinders of the air-operated motor. The air operated motor comprises cylinder, piston, rod, rotor, and crank. The link between the rod of the piston and crank is in pulse forward-rotation motion and sets the crank in rotation. EFFECT: enhanced efficiency.
Patent RU-94039492-A (RU)
Inventor: IGNASHKOV E I
IPC: F16K3/08
Filed: 1994-10-18
Abstract: FIELD: mechanical engineering; valves and pipe fittings. SUBSTANCE: proposed device is of one-chamber design. It has housing with branch pipes with rotary spool valve installed between seats with through holes with slot clearance. Spool valve has bypass holes and extensible sealing disk with bypass holes and cylindrical projections with channels to deliver medium into cylindrical cavity, and seats made in spool to receive sealing disk members. Disks are moved apart by springs installed in spool seats providing axial movability of spool and sealing disk. Spool has control member and microvalve to let medium out of spool space and its slot clearance through channels. It has also channel in housing at outlet of pipeline to release pressure from sealing disk in position CLOSED to PARTLY OPEN which is ensured by standard thrust bearing-limiter of axial travel of spool providing metered delivery of pressure medium into device of seat installed in ring cavity over spool periphery and exposed to full pressure differential only for a short time, i.e. beginning of opening of device, and in process of operation, i.e. at pressure drop, it is not exposed to load. Sliding bearing can be used as limiter being made in form of cylindrical projection with medium feed groove and rigidly secured in center of seat and arranged with other end of spherical shape, in spool central seat made through sealing disk. Support release antifriction bearing is installed between sealing disk and seat. Bearing is made with variable axial size owing to flexing of springs installed on seats for balls with device in CLOSED position. Path is made on seats at level of common horizontal path and working race of bearing secured in seat cavity, other race being secured in sealing disk cavity. Bearing is installed to form thinnest slot clearance between disks in OPEN positions to provide its release from load by medium in this position and provide sealing in CLOSED position. This principle can be used for designing through-way gates with straight paths with four solids of revolution (balls) of release bearing. EFFECT: simplified design, increased service life.
Patent RU-94042719-A (RU)
Inventor: KHING CHEUNG TSE
IPC: A23L29/238
Filed: 1993-02-24
Abstract: FIELD: food industry. SUBSTANCE: invention relates to drinking mixtures containing Psyllium (psylla, plant aphid) involving food acid (for example, citric acid) and granulated less soluble food base (for example, calcium carbonate agglomerated with maltodextrin). EFFECT: enhanced quality of the end product.
Patent RU-94043800-A (RU)
Inventor: VIL FRID GUTKNEKHT
IPC: C01B13/14
Filed: 1994-12-13
Abstract: FIELD: chemical industry. SUBSTANCE: claimed process for preparing difficultly soluble metal hydroxides of general formula: M(OH), wherein M is cobalt, zinc, nickel and/or copper, and x is metal valency, comprises reacting compound of initial metal or initial metals with complexing agent and with salt, reacting the resulting metal caustic lye complex and separating the difficultly soluble metal hydroxide. The compound of initial metal or initial metals is reactive metal hydroxide, and the salt is alkali metal salt. The resulting metal-caustic lye complex salt is reacted at pH of greater than 7. EFFECT: more efficient preparation process.
Patent RU-94045601-A (RU)
Inventor: STUDENOV V V
IPC: F01B1/08
Filed: 1994-12-30
Abstract: FIELD: mechanical engineering; piston displacement machines; internal combustion engines, compressors and other machines. SUBSTANCE: power no-connecting rod mechanism of known design has additional spool type distributing device whose shaft is coupled with crank pin by means of carrier. Piston machine operates as follows: working medium is pressure-fed through open slot of hollow shaft of spool along pipeline into working space between cylinder wall and piston, making the piston move to center. Slider, coupled with pistons, acts onto pin which is already set into motion under action of pistons of other pair of cylinders. These motions, being added up, cause rotation of disk and output shaft. During piston stroke, pin turns spool shaft through 180 degrees by means of carrier, pipeline gets overlapped. Other pipeline opens and piston is exposed to pressure of working medium passing along pipeline making slider move backwards following continuous movement of pin over circumference. Other pair of cylinders operates in the similar manner, but with 90 degrees shift to provide passing over dead centers. EFFECT: reduced loads, improved operating conditions of mechanism when used on multicylinder engine owing to synchronization of cylinder operation.
Patent RU-95101515-A (RU)
Inventor: MOVCHANJUK V M
IPC: E04B1/02
Filed: 1995-02-01
Abstract: FIELD: civil engineering. SUBSTANCE: according to method, number of storeys in building is increased by adding 1 m width to both sides of building with retaining structural layout of existing building. Increasing number of storeys and width of building is effected on independent load-bearing structures which embrace existing building. Due to that, all loads caused by increased number of storeys are transmitted to new foundations not actually connected with existing ones. This substantially cuts cost for reconstruction of five- storey residential buildings and improves quality of new apartments. EFFECT: high efficiency.
Patent RU-95101726-A (RU)
Inventor: GORODINSKAJA V S
IPC: A61K36/899
Filed: 1995-02-17
Abstract: FIELD: medicine. SUBSTANCE: method involves combination of psychotherapy and oral administration of balsam "Violetta-original" at daily dose 100-200 g for 30-40 days, medicinal herb species and applying cream "Bioton-Violetta" on skin. During treatment verbal suggestion of positive sensations is carried out. In the process of treatment course 5-6 cleansing enemas were carried out that contain balsam "Violetta". Method ensures to treat diseases of gastroenteric tract, liver, kidney, lung, diabetes mellitus, atherosclerosis, hypertension and many others and results of ionizing radiation small doses. EFFECT: enhanced effectiveness.
Patent RU-95103225-A (RU)
Title: Space-saving nondirectional linearly or elliptically polarized antenna
Inventor: GOL JANOV JU V
IPC: H01Q21/24
Filed: 1995-03-07
Abstract: FIELD: communication lines; aeronautical communication; linear telemechanic systems; telemetry, etc. SUBSTANCE: antenna has strip of half-wave dipoles joined together by means of two parallel bracing rods through insulating washers; half-wave dipoles are made in the form of cylinders shortened due to end capacitors and provided with two coaxial holes one of greater diameter and other of smaller one to receive bracing rods; each next dipole of antenna strip is turned through 180 deg relative to plane passing through axes of dipole holes; bracing rods contacting dipole body in smaller-diameter holes of same diameter as holes function as external conductor of linearly polarizing circuit. Bracing rods in larger-diameter holes of the same diameter as linearly polarizing circuit being used function as internal conductors of linearly polarizing circuit; capacitive coupling of integral and external conductors of linearly polarizing circuit is provided through insulating washers between dipoles. For shaping nondirectional elliptically polarized directivity patterns, insulating washer between dipoles is replaced by round dipole antenna arrays assembled on printed-circuit boards and placed in center of wave cylindrical dipoles. EFFECT: provision for shaping nondirectional linearly or elliptically polarized directivity pattern; simplified design and improved operating reliability of antenna.
Patent RU-95105833-A (RU)
Inventor: POPKOV I I
IPC: F02B75/32
Filed: 1995-04-14
Abstract: FIELD: valve timing gears of internal combustion engines. SUBSTANCE: valve timing gear gas two cam plates secured on shaft of engine of rotary type, for example. Cams are engageable with rollers of respective rods which perform reciprocating motion and act on one arm of double-arm levers; second arm of each double-arm lever acts on respective intake and exhaust valves of engine piston cylinders; rotor of engine is mounted on common shaft with cam plates. EFFECT: enhanced reliability.
Patent RU-95106942-A (RU)
Inventor: ZHESKO T E
IPC: B01J31/20
Filed: 1995-05-03
Abstract: FIELD: catalytic processes in chemistry. SUBSTANCE: invention relates to methods of preparing catalysts for carbonylation of organic halides under mild conditions (up to 5 atm pressure of carbon monoxide). Cobalt salts are treated with carbon monoxide and hydrogen mixture at (4:10):1 ratio in a C-C-aliphatic alcohol medium at 110-130 C and 30-50 atm pressure in presence of cobalt octacarbonyl catalyst or alcohol solution of cobalt octacarbonyl catalyst containing 5-20% of catalytically active cobalt based on total amount of loaded cobalt. Reaction having been finished, obtained solution is cooled and treated with CO under 5-15 atm pressure for 5-60 min. When catalyst was used for 1- chloronaphthalene carbonylation, conversion was 90-94% and yield of target product 83.4-83.9%. EFFECT: increased activity and selectivity of catalyst.
Patent RU-95108838-A (RU)
Inventor: TIMASHEV A T
IPC: E21B43/00
Filed: 1995-05-30
Abstract: FIELD: oil production industry. SUBSTANCE: increased flow rate capacity of subsurface pumping units and reduced oil production cost can be achieved as follows. Well product received from bed directly enters lifting pump-compressor tubes lowered down to perforated holes or when pad of lifting tube string is located at given height from well bottom-hole with retention of pressure at pad opening. In certain cases (when bed pressure is high or when string lowering depth is limited due to technical or economical reasons) it can be located at preset height above bottom-hole. Well product lifting through pump-compressor tubes (through tail-piece) above zone of starting degassing passes through evaporation-ejector regulator in which due to sharp widening of cross-sectional area take place is separation of lighter fractions from heavier fractions, additional evaporation and ejection which intensify degassing which allows for considerable reduction of density of gas-liquid mixture in tail-piece. Further, this mixture enters subsurface pumping unit which is located at optimal preset height determined proceeding from need to ensure pumping of optimal amount of liquid at minimal specific cost per one ton of product obtained from well. For this purpose, excluded from subsurface pumping unit is suction valve and use is made of double-chamber subsurface pumping unit with two plungers which are separated from each other by dividing partition. At reciprocating motion of these plungers, created in chambers is rarefaction space promoting additional separation of gas from product delivered from well. This action is enhanced by suction operation of plungers and ejector located in hollow rod of lower plunger, thus creating conditions for continuous flow of gas-liquid mixture through this device. Gas-liquid mixture is pumped out continuously both at downward and upward strokes of plungers, with utilizing for lifting that energy which is produced due to liberation of gas from well liquid into free space. EFFECT: high efficiency.
Patent RU-95110561-A (RU)
Inventor: ZHILIN A N
IPC: A01D34/01
Filed: 1995-06-27
Abstract: FIELD: agriculture, mechanical engineering, in particular, cutting of different materials, including constructional materials. SUBSTANCE: method involves providing flowing of high-pressure medium stream from nozzle device of hydraulic cutting equipment; directing stream to object moving relative to it; selecting object feeding value S, calculated by formula:, where d is diameter of cutting stream, m; V is stream flow rate, m/sec; ρ is density of cutting stream, kg/cub m; n is proposed number of passes; t(sh) is shear-through- thickness strength of material of object under cutting process; H is thickness of object, m; K - 1-1.9 is experimental coefficient depending on n value. EFFECT: increased speed and efficient working of strong and high-strength materials, wider operational capabilities.
Patent RU-95110593-A (RU)
Inventor: MINASJAN M A
IPC: F16F15/08
Filed: 1995-06-23
Abstract: FIELD: mechanical engineering; suppression of harmful vibrations. SUBSTANCE: support has special device which provides compression of resilient member irrespective of direction of extending or compressing load. Device consists of upper and power pressure plates placed between resilient member and support plates and intercoupled by bolt connections in special manner. Pressure plates can be made of metal, or nonmetallic or composite materials, either with or without perforation. EFFECT: increased reliability and longevity of support resilient member; improved efficiency of vibration isolating support at different-direction static and dynamic loads; possibility of adjustment of support. 1 cl, 10 dwg