baber/WOPTO huggingface dataset:
Patent CA-3103371-A1 (CA)
Title: Treatment using oncolytic virus
Inventor: COFFIN ROBERT STUART
IPC: A61K39/39
Filed: 2019-06-21
Abstract: An oncolytic virus for use in a method of treating or preventing cutaneous squamous cell carcinoma (CSCC), renal cell carcinoma (RCC), non-small cell lung cancer (NSCLC), triple negative breast cancer (TNBC), small cell lung cancer (SCLC), advanced recurrent head and neck cancer, squamous cell carcinoma of the head and neck (SCCHN), nasopharyngeal carcinoma (NPC), hepatocellular carcinoma (HCC), anal cancer, colorectal cancer (CRC), basal cell carcinoma (BCC), Merkel cell carcinoma, appendiceal carcinoma, sarcoma of the skin, recurrent melanoma after surgery, advanced or metastatic urothelial carcinoma, liver metastases, microsatellite instability high cancer (MSI-H), mixed advanced solid tumors, virally caused cancer, locoregionally advanced cancer, pediatric cancer, cancer in patients with no or minimal pre-existing anti-cancer immunity, cancer as first line therapy, cancer in previously treated patients, cancer in patients who have not received checkpoint blockade therapy, and/or cancer in patients who have received checkpoint blockade therapy, wherein the oncolytic virus: is, or is derived from, a clinical isolate which has been selected by comparing the abilities of a panel of three or more clinical isolates of the same viral species to kill tumor cells of two or more tumor cell lines in vitro and selecting a clinical isolate which is capable of killing cells of two or more tumor cell lines more rapidly and/or at a lower dose in vitro than one or more of the other clinical isolates in the panel; comprises (i) a fusogenic protein-encoding gene; and (ii) an immune stimulatory molecule or an immune stimulatory molecule-encoding gene; comprises (i) a GM-CSF-encoding gene; and (ii) an immune co-stimulatory pathway activating molecule or an immune co-stimulatory pathway activating molecule-encoding gene; and/or comprises a gene encoding a CTLA-4 inhibitor.
Patent CA-3105208-A1 (CA)
Inventor: LANFREY PIERRE-YVES
IPC: C10G5/06
Filed: 2021-01-08
Abstract: 41 Abrégé La présente invention concerne un dégazolinage d'un gaz G, avec (a) une étape de dégazolinage du gaz à traiter comprenant du méthanol GM issu de l'étape (d), (b) une étape de séparation dudit fluide partiellement condensé GL1 à l'étape (a) , produisant - une première phase liquide aqueuse Al, - une première phase liquide H1 d'hydrocarbure(s) - une phase gazeuse G1 issue du gaz G ; __ (c) une étape de contactage d'une partie du gaz G à traiter avec ladite première phase liquide aqueuse Al , produisant - une deuxième phase liquide aqueuse A2 - une phase gazeuse de gaz à traiter comprenant du méthanol GM' ; (d) une étape de mélange de ladite phase gazeuse de gaz à traiter comprenant du méthanol GM' avec le reste du gaz G à traiter, produisant un gaz à traiter comprenant du méthanol GM (e) une étape de stabilisation de ladite première phase liquide H1 d'hydrocarbure(s). Figure 1 à publier. Date Reçue/Date Received 2021-01-08
Patent CA-3105845-A1 (CA)
Inventor: RIOU KELLY
IPC: A63B69/00
Filed: 2021-01-14
Abstract: A removeable off-ice training blade for use in a convertible ice skate on a non-ice training surface. The blade has an upper retention surface shaped to engage the interior of a blade-holding groove and retention mechanism of the skate and has a lower training surface to engage the non-ice training surface having two side surfaces extending substantially perpendicularly from the upper retention edge to meet the lower training edge in reflective non-cutting axial edges. The non-cutting axial edges of the training blade are rounded, to negate any destruction of the non-ice training surface during use of the skate by the wearer thereon and the training blade can be removed from the skate for replacement with a removeable skating blade having cutting edges for use on ice as required. A skate incorporating the blade is also disclosed.
Patent CA-3106556-A1 (CA)
Title: Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication
Inventor: JACOBSON IRINA C
IPC: A61P31/16
Filed: 2019-07-26
Abstract: Provided herein are compounds of Formula A, B or C that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.
Patent CA-3106955-A1 (CA)
Inventor: FETVEDT JEREMY ERON
IPC: F02C3/34
Filed: 2019-07-23
Abstract: The present disclosure provides systems and methods wherein power production can be achieved with combustion of a fuel utilizing flameless combustion. A fuel may be combusted in a combustor/turbine in a substantially flameless operation to produce a combustion product stream that can be expanded for power generation. After expansion, the output stream can be treated to generate a recycle CO2 stream into which an oxidant can be input. The recycle CO2 stream including the oxidant can be injected into the combustor/turbine to effect combustion in a substantially flameless state. Various control schemes can be implemented to automatically control the concentration of oxygen present in the recycle CO2 stream that is injected into the combustor/turbine in order to achieve and/or maintain substantially flameless combustion.
Patent CA-3108838-A1 (CA)
Title: Composition comprising isomers of inositol and its use
Inventor: SILVA ZOLEZZI IRMA
IPC: A61P3/10
Filed: 2019-08-22
Abstract: A combination of scyllo-inositol and myo-inositol, wherein, the scyllo-inositol and myo-inositol are nutritional ingredients for use in the prevention or treatment of a condition selected from the group consisting of prediabetes, type II diabetes, gestational diabetes mellitus and a condition associated with any of the forgoing in a subject, and a composition comprising scyllo-inositol and myo-inositol.
Patent CA-3109345-A1 (CA)
Title: Feed compositions and feed additive compositions for aquaculture species
Inventor: KOPPIEN-FOX JESSICA ELIZABETH
IPC: A23K50/80
Filed: 2019-08-28
Abstract: Embodiments of the present disclosure describe feed compositions and feed additive compositions for aquaculture species comprising one or more essential oils, one or more extracts, one or more emulsifiers, one or more carriers, and optionally one or more lactate compounds. Embodiments of the present disclosure further describe methods of administering said compositions, methods of preparing compositions, and the like.
Patent CA-3110013-A1 (CA)
Inventor: RAATS JOZEF MARIA HENDRIK
IPC: C07K16/18
Filed: 2019-08-20
Abstract: The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated pathologies.
Patent CA-3110712-A1 (CA)
Title: Monovalent selective cation exchange membrane
Inventor: GU GEORGE
IPC: B01J47/12
Filed: 2019-09-25
Abstract: A monovalent selective ion exchange membrane is disclosed. The membrane includes a polymeric microporous substrate, a cross-linked ion-transferring polymeric layer on a surface of the substrate, and a charged functionalizing layer covalently bound to the ion-transferring layer. A method of producing a monovalent selective cation exchange membrane is also disclosed. The method may include chemically adsorbing a styrene intermediate layer to a cross-linked ion-transferring polymeric layer on a surface of a polymeric microporous substrate, chlorosulfonating the styrene intermediate layer to attach a sulfonyl chloride group layer, aminating the sulfonyl group layer to attach an amine group layer, and functionalizing the amine group layer with a charged compound layer to produce the cation exchange membrane. Water treatment systems including the monovalent selective cation exchange membrane and methods of facilitating water treatment including providing the monovalent selective cation exchange membrane are also disclosed.
Patent CA-3110952-A1 (CA)
Inventor: RANA JATINDER
IPC: A23L33/105
Filed: 2019-07-12
Abstract: A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the genus Anacardium.
Patent CA-3111481-A1 (CA)
Title: A paint booth assembly and a scrubber unit
Inventor: DE BORCHGRAVE ADRIEN
IPC: B05B14/468
Filed: 2019-10-01
Abstract: A paint booth assembly (20) includes a paint booth (22) having a pair of side walls (26) and a flood sheet (36) extending between the pair of side walls to separate the paint booth between a spray portion disposed above the flood sheet and a paint recovery portion disposed below the flood sheet. The flood sheet defines at least one flood sheet opening (48), and a scrubber unit (24) extends down from the flood sheet opening to establish a shared path of fluid communication of a flow of water from the flood sheet and a downdraft of process air from the spray portion to the paint recovery portion. A scrubber pod (70) is disposed within the scrubber unit and defines a plurality of perforations (72) to induce an initial mixing of the paint particles entrained in the downdraft of process air into the flow of water.
Patent CA-3113115-A1 (CA)
Inventor: KOUSARIDAS APOSTOLOS
IPC: H04L12/24
Filed: 2018-09-17
Abstract: The present invention relates to providing a quality of service function for the communication services in the communication networks. The invention specifically presents a device for providing a quality of service (QoS) function, for at least one communication service of at least one application entity in a communication network comprising a plurality of network entities. The device is configured to transmit a monitoring request to one or more of: the at least one application entity, at least one network entity, and at least one user equipment, obtain a monitoring response from one or more of: the at least one application entity, the at least one network entity, and the at least one user equipment, determine a change in QoS of the at least one communication service of the at least one application entity, based on the obtained monitoring response, and transmit the determined change in the QoS to the at least one application entity and/or at least one of the network entities in the communication network.
Patent CA-3113732-A1 (CA)
Inventor: JIANG LEI
IPC: C07D471/04
Filed: 2019-09-23
Abstract: Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for preparing pharmaceutical compositions for treating cancers and other diseases associated with JAK activity.
Patent CA-3114569-A1 (CA)
Title: Terminal utilisateur, et station de base
Inventor: TAKAHASHI HIDEAKI
IPC: H04W72/04
Filed: 2018-09-28
Abstract: Un terminal d'utilisateur selon un aspect de la présente divulgation comprend une section de réception recevant des informations de commande de liaison descendante comprenant un domaine donné indiquant une ressource de domaine fréquence attribuée à un canal partagé de liaison descendante, et une section de commande qui commande la réception du canal partagé de liaison descendante selon si une ressource de commande établie pour un espace de recherche commun est configurée d'après un bloc d'informations primaires.
Patent CA-3115236-A1 (CA)
Inventor: BLAIR WILLIAM ALAN
IPC: B01L9/06
Filed: 2019-10-04
Abstract: A container includes a vial, cap, and one or more wireless transponders secured to the cap, the vial or a jacket to store and identify samples of biological material at cryogenic temperatures (e.g., vitrified biological samples), for instance held by cryopreservation storage devices. A specimen holder may be extend from the cap. The vial and/or cap includes ports or vents. A carrier includes a box, thermal shunt, thermal insulation to store and identify arrays of containers that hold cryopreservation storage devices with samples of biological material at cryogenic temperatures. Various apparatus include wireless transponders positioned and oriented to enhance range, and allow interrogation while retained in a carrier. Various apparatus can maintain the biological material at or close to cryogenic temperatures for prolonged period of times after being removed from a cryogenic cooler, and can allow wireless inventorying while maintaining the biological samples at suitably cold temperatures.
Patent CA-3115283-A1 (CA)
Inventor: WESTARP CHRISTIAN
IPC: B65B1/48
Filed: 2019-09-24
Abstract: The invention relates to a filling unit (1) for a packaging machine (100) for filling containers (60) with bulk material (50) and to a packaging machine comprising a filling unit (1), comprising a conveyor device (2), by means of which bulk material (50) can be conveyed into a container (60), and a controller (3), which is suitable for and designed to control a filling flow (4) into a container (60). A fill level sensor device (5) is provided with a sensor device (6), which is suitable for and designed to detect a first fill level (7) and a second fill level (8) of bulk material (50) in a container (60), wherein the first fill level (7) corresponds to a lower fill level than the second fill level (8). The controller (3) regulates the filling flow (4) using the fill levels ascertained by the sensor device (6). In a method according to the invention, the container is filled until the second fill level is detected. The filling flow is then reduced until the first fill level is detected, and the filling flow is then increased.
Patent CA-3115546-A1 (CA)
Inventor: SCULLIN MATT
IPC: C12N1/14
Filed: 2019-10-25
Abstract: An abrasion resistant finish for a fungal material, the finishing comprising an optimum quantity biodegradable polylactic acid plastic (PEA) dispersed in water to produce a PEA mixture. When the PEA mixture is applied to the fungal material, water carries the PEA deeply into the matrix of the fungal hyphae to a depth at least 2 N/10 mm or 1% of the thickness of the fungal material, whichever is greater. The finish fortifies the hyphal structure as the water evaporates and creates a PEA coating on the fungal material with improved abrasion resistance and water resistance.
Patent CA-3117870-A1 (CA)
Title: 7-phenoxy-n-(3-azabicyclo[3.2.1]octan-8-yl)-6,7-dihydro-5h-pyrrolo[1,2-b][1,2,4]triazol-2-amine derivatives and related compounds as gamma-secretase modulators for the treatment of alzheimer's disease
Inventor: FREI BEAT
IPC: A61P25/28
Filed: 2019-12-11
Abstract: The invention provides 7-phenoxy-N-(3-azabicyclo[3.2.1]octan-8-yl) -6,7-dihydro-5H-pyrrolo[l,2-b][l,2,4]triazol-2-amine derivatives and related compounds of the general formula (I) wherein R1, Ar, n and m are as described herein, compositions including the compounds, processes of manufacturing the compounds and the compounds for use in methods of medical treatment. The present compounds are as gamma-secretase modulators for the treatment of diseases associated with the deposition of ß-amyloid in the brain, such as Alzheimer's disease, cerebral amyloid angiopathy, cochlear synaptopathy, hearing loss, hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome. The present description discloses the preparation of exemplary compounds as well as pharmacological data thereof (e.g. pages 54 to 74; examples 1 to 64; table). An exemplary compound is e.g. (R)-7-(3,5-difluorophenoxy)-N- ((lR,5S,8s)-3-(6-methoxypyridazin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl) -6,7-dihydro-5H-pyrrolo[l,2-b][l,2,4]triazol-2-amine (example 1).
Patent CA-3122506-A1 (CA)
Title: Emm-41 composition, methods of making and uses thereof
Inventor: MABON ROSS
IPC: B01D15/00
Filed: 2019-11-12
Abstract: This disclosure relates to EMM-41 materials, methods for making it, and processes for its use. This disclosure also relates to the structure directing agents used in the methods for making the EMM-41 material as well as the synthesis method used to prepare such structure directing agents.
Patent CA-3124087-A1 (CA)
Inventor: PEIKOFF MICHAEL
IPC: A61F6/04
Filed: 2019-03-07
Abstract: A condom and/or prophylactic device including an enclosed end configured to collect and securedly maintain bodily fluids and/or semen therein during intercourse; an open end that is spaced apart from the enclosed end that is further configured to receive a penis therethrough; and a main body positioned between and connected to the enclosed end and open end thereby forming a partial enclosure configured to receive and surround the penis therein and having an opening positioned mid-span along a length of the main body that is configured to allow skin on skin contact between the condom wearer and companion while in use.
Patent CA-3124687-A1 (CA)
Inventor: MAKITA YOSHIMICHI
IPC: A61K31/198
Filed: 2020-04-02
Abstract: L'invention concerne une composition pharmaceutique qui contient de l'acide 3-{[(2S)-2-amino-2-carboxyéthyl]carbamoylamino}-5-chloro-4-méthylbenzène sulfonique, un sel pharmaceutiquement acceptable de celui-ci, ou un solvate de celui-ci, qui présente un pH de 8,0 maximum, et une stabilité de composition pharmaceutique favorable.
Patent CA-3127486-A1 (CA)
Title: Systems and methods for modulating crispr activity
Inventor: KELSO REED
IPC: C12P19/30
Filed: 2020-01-25
Abstract: Provided herein are polynucleotides comprising sequence configured to bind to a CRISPR effector protein. Modulation of one or more modifications of the polynucleotides can be used to tune the activity of CRISPR effector proteins complexed with the polynucleotides.
Patent CA-3128127-A1 (CA)
Title: Preparation pour la prevention de maladies acquises par l'intermediaire de la cavite buccale et du pharynx
Inventor: MONTES JOSEPH G
IPC: A61K8/19
Filed: 2020-03-16
Abstract: L'invention comprend une pâte dentifrice ou un autre produit appliqué par voie orale à utiliser au moins une fois par jour pour aider à prévenir ou à inhiber l'acquisition d'un certain nombre d'infections par des tissus oraux ou pharyngiens, comprenant particulièrement le rhume "banal". Ces compositions possèdent une combinaison d'ingrédients qui ne se trouvent pas dans d'autres pâtes dentifrices ou d'autres produits appliqués par voie orale et ces ingrédients fonctionnent ensemble pour interférer de manière synergique avec l'acquisition d'un certain nombre d'agents pathogènes. Les pâtes dentifrice ont les ingrédients de dentifrice classiques connus pour empêcher une carie ainsi que ceux qui réduisent l'halitose (c'est-à-dire la mauvaise haleine) et empêchent la gingivite. De plus, les pâtes dentifrice comprennent un élément ou plus parmi les suivants : 1) du GALALCOOL ® en tant que composé individuel et non en tant que constituant d'un extrait ; 2) du protoporphyrine zinc IX ; et 3) un ou plusieurs autres tanins incolores ou à faible couleur, chacun en tant que composé individuel et non en tant que constituant d'extrait.
Patent CA-3130989-A1 (CA)
Title: Cookware liner
Inventor: RICHARDSON KENDRA
IPC: A47J36/16
Filed: 2021-09-16
Abstract: A cookware liner that is configured to be disposed within the interior volume of a cooking appliance such as but not limited to a crockpot so as to inhibit food from contacting the interior surfaces of the cookware. The cookware liner of the present invention is manufactured from silicone so as to facilitate multiple re-uses thereof. The present invention includes a body having a bottom and a wall integrally formed to create an interior volume. The body is formed of a size and shape so as to be mateably inserted into the interior volume of the cookware. The body includes a perimeter lip member proximate the upper end thereof. The perimeter lip member extends outward from the wall of the body and is configured to be biased in between the top of the cookware and a lid thereof so as to inhibit the body from collapsing into the cookware.
Patent CA-3132166-A1 (CA)
Title: Removable roller with rotation indicator
Inventor: HARMON ANDREW
IPC: A01C7/06
Filed: 2021-09-28
Abstract: One or more techniques and/or systems are disclosed for metering assembly for an agricultural seeder. The metering assembly can be configured for quick and easy removal and replacement, where merely the assembly is removed without disassembling other parts of the seeder system. An improved coupler, in conjunction with a threaded knob device, allows for quick and easy access to the assembly, for removal and replacement in a metering tube. A visual indicator can be disposed on the end of a rotating shaft to provide a user with a quick confirmation that the assembly is properly rotating during operation.
Patent CA-3133449-A1 (CA)
Title: Systemes et procedes d'imagerie et d'evaluation arterielle et flux de travaux bases sur une interface utilisateur associes
Inventor: GOPINATH AJAY
IPC: A61B5/00
Filed: 2020-03-17
Abstract: En partie, l'invention concerne un procédé permettant d'afficher une représentation d'une artère. Le procédé peut consister à : stocker un ensemble de données d'image intravasculaire dans un dispositif mémoire d'un système d'imagerie de diagnostic, l'ensemble de données d'image intravasculaire étant généré en réponse à une imagerie intravasculaire d'un segment d'une artère ; détecter automatiquement une limite de lumière du segment sur une base par trame ; détecter automatiquement une EEL et afficher un flux de travaux de dimensionnement de stent. En partie, l'invention consiste également à : détecter automatiquement une ou de plusieurs zones de calcium par rapport à la limite de lumière du segment ; calculer une mesure angulaire ou circonférentielle du calcium détecté pour une ou plusieurs trames ; calculer une épaisseur du calcium détecté pour une ou plusieurs trames ; et afficher l'épaisseur de calcium et la mesure angulaire ou circonférentielle du calcium détecté pour une première trame parmi les trames.
Patent CA-3133498-A1 (CA)
Inventor: HAO JINPING
IPC: H04W4/02
Filed: 2020-03-12
Abstract: Provided in the present application is a method for positioning a user equipment (UE), the method comprising: a first base station receiving first measurement information, the first measurement information being obtained by a UE measuring a signal sent by the first base station; the first base station determining first intermediate information according to the first measurement information and first auxiliary information of the first base station, the first intermediate information being used to determine location information of the UE; and the first base station sending the first intermediate information to a first network device. Thus, a UE is positioned when the position of the UE cannot be determined by means of measurement information reported by the UE.
Patent CA-3137714-A1 (CA)
Title: Methods and compositions for next generation sequencing (ngs) library preparation
Inventor: MONTGOMERY JESSE L
IPC: C12P19/34
Filed: 2020-04-24
Abstract: Disclosed herein are primer/adapter sequences, wherein each of the primer/adapter sequences comprise a region that hybridizes with a target nucleic acid sequence, as well as an adapter sequence that does not hybridize with the target nucleic acid sequence. Also disclosed are methods of using these primer/adapter sequences to amplify and sequence target nucleic acid sequences in a sample.