baber/WOPTO huggingface dataset:
Patent NZ-280325-A (NZ)
Title: 19-norsteroid derivatives having a 17-spiromethylene lactone group
Inventor: HAMERSMA JOHANNES ANTONIUS MAR
IPC: C07J31/00
Filed: 1995-10-25
Abstract: A steroid with a 17-spiromethylene lactone group having formula I   <CHEM> wherein R1 is O, (H,H), (H,OR), or NOR, R being selected from H, (1-6C) alkyl and (1-6C) acyl; R2 is H, (1-6C) alkyl optionally substituted by a halogen, (2-6C) alkenyl optionally substituted by a halogen, (2-6C) alkynyl optionally substituted by a halogen, or halogen; R2' is H; or R2' together with R2 is a (1-6C) alkylidene group or a (2-6C) alkenylidene group; or R2' together with R3 is a bond; R3 is H if not together with R2' a bond; R4 is (1-6C) alkyl; one of R5 and R6 is hydrogen and the other is hydrogen or (1-6C) alkyl; X is (CH2)n or (CnH2n-2) wherein n is 2 or 3, which is optionally substituted with hydroxy, halogen, (1-6C) alkyl, (1-6C) acyl, (7-9C) phenylalkyl, the phenyl group of which may be substituted with (1-6C) alkyl, (1-6C) alkoxy, hydroxy or halogen; Y is O or (H,OH); and the dotted lines indicate optional bonds, at least one of bonds 4-5, 5-10, and 9-10 being a double bond. The steroids of the invention have progestational activity and can be used as contraceptives.
Patent NZ-280989-A (NZ)
Title: Clock frequency assignment for space division multiple access radio system
Inventor: TANGEMANN MICHAEL
IPC: H04Q7/36
Filed: 1996-02-14
Abstract: The carrier frequency assigning system only allows the same carrier frequency to be assigned to different mobile stations (MS1,..MS3) when the directions of the mobile stations relative to the fixed station (BTS) differ from one another by a given min. angle and the received radio signal levels lie within defined a defined reception level range. Pref. the required difference angle between the mobile stations is varied in dependence on the distance of the mobile stations from the fixed station and the reception level is matched to the dynamic parameters of the radio device.
Patent NZ-284422-A (NZ)
Title: Filter sleeve for a draining element of a press has an elastically deformable part with a ring shaped bead fixed to one end
Inventor: HARTMANN EDUARD
IPC: B30B9/26
Filed: 1995-05-09
Abstract: PCT No. PCT/CH95/00107 Sec. 371 Date Jan. 19, 1996 Sec. 102(e) Date Jan. 19, 1996 PCT Filed May 9, 1995 PCT Pub. No. WO95/32090 PCT Pub. Date Nov. 30, 1995A filter sleeve (26) surrounds a rod-shaped, flexible drain core with flow paths for removing a pressed-out liquid from the pressing chamber of a press. For mounting one or both ends of the filter sleeve (26) and the drain core on the press, a rubber or elastically deformable shaped element (29) with a ring-like bead (22) is firmly connected with the filter sleeve (26) at its end. The shaped element (29) inseparably penetrates the fabric of the filter sleeve (26) because of an elastomer coating, and the bead (22) is automatically positioned in a groove (24) of a support body (23) because of its previous stretching.
Patent NZ-298960-A (NZ)
Title: A multi-layered heat-shrinkable film
Inventor: BAX SERGE
IPC: C08J5/18
Filed: 1995-12-15
Abstract: This heat-shrinkable film comprising a core layer comprises an ethylene-vinyl alcohol copolymer, two outer layers of blends comprising ethylene-vinyl acetate and ethylene-a-olefin copolymers, and two adhesive layers, characterized in that the film has a free shrink of at least 40 %, preferably at least 45 % and most preferably at least 50 %, in both dimensions at 120 C and a maximum shrink force in the transversal direction, throughout its range of shrink temperatures, not exceeding 0.5 N/cm.  The film is suitable to package deformable articles such as trays to give a tight package without causing deformation.
Patent NZ-319644-A (NZ)
Title: Gambling chip containing microcircuit comprises two plastic half discs separated by spacing rings
Inventor: GASSIES CHRISTOPHE
IPC: A44C21/00
Filed: 1996-10-07
Abstract: PCT No. PCT/FR96/01558 Sec. 371 Date Dec. 20, 1996 Sec. 102(e) Date Dec. 20, 1996 PCT Filed Oct. 7, 1996 PCT Pub. No. WO97/13424 PCT Pub. Date Apr. 17, 1997The gambling chip 10, having the general shape of a disc, includes two identical half-discs 11 and 12 in contact via axial spacing rings 21 and 22 respectively located on their internal faces. The half-discs 11 and 12 made of rigid plastic are fastened together by injection of a plastic seal 14 on the edge 35 of the chip into a peripheral annular region 16 lying between the two half-discs 11 and 12. The half-discs 11 and 12 have a central recess 26, 27 forming an internal central region 28 taking an electronic identification device 30 embedded in a wafer based on epoxy resin.
Patent NZ-331298-A (NZ)
Title: Recombinant (humanised) ribonuclease proteins derived from a native ribonuclease found in the oocytes of Rana pipiens and uses therefor
Inventor: RYBAK SUSANNA M
IPC: C12N15/55
Filed: 1997-02-19
Abstract: The invention relates to ribonucleases derived from a native ribonuclease found in the oocytes of Rana pipiens. Various humanized and recombinant forms of these molecules are described as well as uses for them. The inventors had constructed recombinant ribonucleases that are highly cytotoxic after modification of the native ribonuclease. The inclusion of portions of mammalian or human-derived ribonucleases such as angiogenin or human eosinophil derived neurotoxin seems to be useful in the treatment of tumours sensitive to cytotoxic reagents.
Patent NZ-333196-A (NZ)
Title: Process for preparing microparticles from risperidone and a solvent and use
Inventor: RICKEY MICHAEL E
IPC: B01J13/04
Filed: 1997-05-06
Abstract: The invention provides a process for the preparation of biodegradable biocompatible microparticles, said process comprising: contacting microparticles comprising a biodegradable biocompatible polymer matrix containing an active (e.g. pharmaceutical or diagnostic) agent selected from risperidone, 9-hydroxyrisperidone and an organic solvent selected from an ester and a second solvent from benzyl alcohol with an aqueous solvent system comprising water and a C1-4 alcohol whereby the content of said organic solvent in said particles is reduced to 2 % or less of the weight of said particles, said solvent system being such as to satisfy at least one of the conditions (a) that it is at an elevated temperature (e.g. from 25 to 40 °C) during at least part of the time that it is in contact with said particles, and (b) that it comprises water and water-miscible solvent for said organic solvent; and recovering said particles from said aqueous solvent system.
Patent NZ-333232-A (NZ)
Title: Use of p-aminophenol derivatives (paracetamol) to treat neurodegenerative disease
Inventor: PINZA MARIO
IPC: A61K31/167
Filed: 1997-05-15
Abstract: The specification describes the use of p-aminophenol derivatives such as paracetemol or phenacetin or their prodrugs to treat neurodegenerative diseases and in particular Alzheimer disease.
Patent NZ-337621-A (NZ)
Title: Electrically controlled actuator comprising a plurality of blades each provided with piezo-electric ceramic material over part of its length
Inventor: POWELL SIMON
IPC: H01L41/09
Filed: 1998-03-06
Abstract: An electrically controlled actuator comprises a plurality of blades 10 each of which extends from a bight portion 35 to form a substantially U-shaped planar substrate 5 having opposed major surfaces.  Each blade is provided with a piezo-electric ceramic material over part of its length with the ceramic material of one blade being on one major surface of the substrate and the ceramic material of the other blade being on the other major surface of the substrate.  The free end of one of the blades is arranged to form a mounting 60 for the actuator.  The free end of the other blade forms the activation portion 85 of the actuator.  The blades may each comprise a flexing portion 10 and a rigid portion 15, the ceramic material being adhered to the flexing portion.
Patent NZ-501624-A (NZ)
Title: Preferential heating of materials by use of non-ionising electromagnetic radiation
Inventor: CAREW DAVID LEE
IPC: A61L2/12
Filed: 1998-06-11
Abstract: A method and apparatus for preferential heating of materials, such as pharmaceuticals and food products, by exposing the material to high intensity, pulsed, non-ionising electromagnetic radiation. The micro-organisms are exposed to pulsed microwave radiation that has a pulse duration of less than 1 second, a pulse frequency of less than 100 pulses per second, an average power of at least 1 kW, and a peak power of at least 3kW which destroys the micro-organisms without the substantial heating of the surrounding environment that is exposed to the radiation.
Patent NZ-502803-A (NZ)
Title: Selective factor Xa inhibitors for treating diseases such as angina, myocardial infarction, transient ischemic attacks or diseases associated with undesired thrombosis
Inventor: SCARBOROUGH ROBERT M
IPC: A61P7/02
Filed: 1998-08-11
Abstract: A class of fused aryl diazepinone compounds selected from general Formula (I) which are potent and specific inhibitors of Xa, their pharmaceutically acceptable compositions thereof, and the methods of using them as therapeutic agents for disease states characterised by abnormal thrombosis. Wherein: A is selected from the group consisting of R8, -NR8R9, or from Formula (II); wherein R8, R9, R10 and R11 are independently selected from the group consisting of H, -OH, C1-6alkyl, aryl and C1-4alkylaryl; R12 is selected from the group consisting of H, C1-6alkyl, aryl and C1-4alkylaryl, or can be taken together with R10 or R11 to form a 5-6 membered ring; and R13 is selected from the group consisting of H, C1-6alkyl, aryl and C1-4alkylaryl, or can be taken together with R11 to form a 5-6 membered ring; D is selected from the group consisting of a direct link, C3-8cycloalkyl, C1-6alkenyl, C1-6alkenylaryl, aryl and a 5 to 10 membered heterocyclic ring system containing 1-4 heteroatoms selected from the group consisting of N, O and S; E is selected from the group consisting of a direct link, -CO-, -SO2-, -O-CO-, -NR14-SO2- and -NR14-CO-, where R14 is selected from the group consisting of H, -OH, C1-6alkyl, aryl and C1-4alkylaryl; K', K", K"' and K"" are independently selected from the group consisting of -CH-, -CR4-, -CR5- and -N-; R4 and R5 are independently selected from the group consisting of H, C1-6alkyl, aryl, C1-6alkylaryl, C1-4alkyloxy, halogen, -NO2, -NR6R7, -NR6COR7, -OR6, -OCOR6, -COOR6, -CONR6R7, -CN, -CF3, -SO2NR6R7 and C1-6alkyl-OR6; where R6 and R7 are independently selected from the group consisting of H, C1-6alkyl, C1-3alkylaryl and aryl; L is selected from the group consisting of R33, -NR33R34 or Formula (III), where R33, R34, R35 and R36 are independently selected from the group consisting of H, -OH, C1-6alkyl, aryl and C1-4alkylaryl; R37 is selected from the group consisting of H, C1-6alkyl, aryl and C1-4alkylaryl, or can be taken together with R35 or R36 to form a 5-6 membered ring; and R38 is selected from the group consisting of H, C1-6alkyl, aryl and C1-4alkylaryl, or can be taken together with R36 to form a 5-6 membered ring; M is selected from the group consisting of a direct link, C1-6alkyl, C3-8cycloalkyl, C1-6alkenyl, C1-6alkenylaryl, aryl, and a 5-10 membered heterocyclic ring system containing 1-4 heteroatoms selected from the group consisting of N, O and S; Q is selected from the group consisting of H or Formula (IV), where R21 and R22 are independently selected from the group consisting of H, C1-3alkyl and aryl;
Patent NZ-503403-A (NZ)
Title: Device for dosing animals with sleeve on syringe extendable and retractable to protect against needle stabs
Inventor: SIMMONDS WAYNE
IPC: A61M5/32
Filed: 2000-03-15
Abstract: An apparatus for attachment to the neck of a syringe for the purpose of orally administering medicament to animals.  The apparatus comprises a piercing means (122) adapted to be attached to the neck of a syringe and a cover means (140).  The cover means is adapted to be adjustably attached directly or indirectly to the piercing means, and can be used in at least two configurations.  The first configuration is with the cover means in a retracted position with the piercing means substantially exposed and a second configuration with the piercing means substantially shrouded by the cover means.  The apparatus is adapted so that in use medicament may be dispensed through the piercing means in the first and second configurations.
Patent NZ-510536-A (NZ)
Title: Increasing intestinal absorption of fats by increasing the amount of lysophosphatidylcholine in the intestine through therapeutic oral administration
Inventor: YESAIR DAVID W
IPC: A61K47/14
Filed: 1999-09-07
Abstract: Described are methods for increasing fat absorption from the intestine by increasing the amount of lysophosphatidylcholine in the intestine.  Any agent which increases intestinal lysophosphatidylcholine can be used, preferably those which are administered orally to the subject.
Patent NZ-518814-A (NZ)
Title: Methods for the treatment and prevention of neurodegenerative conditions
Inventor: ABOU-GHARBIA MAGID ABDEL-MEGID
IPC: A61P21/00
Filed: 2000-11-10
Abstract: Use of adatanserin or a pharmaceutical salt thereof in the preparation of a medicament for the treatment of neurodegenerative disorders.
Patent NZ-522136-A (NZ)
Title: Vaso-active intestinal peptide (VIP) dye conjugates used as contrast agents for optical diagnostics
Inventor: LICHA KAI
IPC: C09B23/08
Filed: 2000-03-28
Abstract: A peptide-polymethine-dye conjugate of formula (I) A1 - (X)M - A2 is described wherein: X stands an a-, b-, g-amino acid with D- or L-configuration M is a number form 5 to 30 Whereby the resulting amino acid sequence (X)m can be cyclized in a straight-chain nature or via a disulfide bridge between two cysteines or homocysteines or amidically between the N- and C-terminus and stands for the amino acid sequence of the vaso-active intestinal peptide (VIP) A1 is H, acetyl radical or an alkyl radical with up to 10 C-atoms, which optionally can be substituted with 1 to 3 carboxy groups and/or 1 to 6 hydroxy groups, or a poly(oxyethylene) radical with 2 to 30 -CH2CH2O units, or a dye molecule from the class of the polymethine dyes which has at least one absorption maximum in the range of 380 to 1200 nm A2 is OH, an amino group or a dye molecule from the class of polymethine, which has at least one absorption maximum in the range of 380 to 1200 nm Provided that at least one of the radicals A1 or A2 represents a dye molecule from the class of polymethine dyes, which has at least one absorption maximum in the range of 380 to 1200 nm Whereby for the case of polymethine dyes which has at lest one absorption maximum in the range of 380 to 1200 nm, A1 is linked to the N terminal amino group and A2 is linked to an amino group of the amino acid lysine or to a hydroxy group of the amino acid serine in any position within the amino acid sequence (X)m and their physiologically salts. Preferably the dye molecule is a cyanine, squarilium, croconium, merocyanine or oxonol dye. The compounds can be used as an optical diagnostic agent for in vivo diagnosis of tumors or adeomas, in vivo fluorescence diagnosis of tumors, tumor cells and inflammatory tissues in the gastrointestinal tract, esophagus, bronchial tract, bladder or cervix and for in vivo fluorescence and/or absorption diagnosis of breast tumors Divided out of 514533
Patent NZ-523619-A (NZ)
Title: A system for automatic collection and transport of readings from water, gas and electricity meters
Inventor: COMAS ROMERO JOSE MARIO
IPC: H04Q9/02
Filed: 2001-06-21
Abstract: A system for the automatic collection and transport of readings from water, gas and electricity meters (4) includes at least one element to transmit the reading from the meter and at least one receiver element (1) of that reading. The at least one element to transmit includes an interface subsystem (3) that adapts the signal from the meter (4) to be processed by a microcontroller subsystem (5), which executes software application and prepares the meter (4) reading to be sent from an radio transmitter subsystem (6) to the at least one receiver element. The at least one receiver element (1) and one element to transmit defines an ad-hoc wireless network, self organizing in an area (A). The readings are transmitted to the next element using multihop techniques according to a routing algorithm: - a value t is assigned to the receiver elements (1), with maximum value T. - if the direct neighbours of a given network node have as a maximum an assigned value t, a value t-k is assigned to this node; - every node will transmit a message to a node with t value larger than its own and - if there is more than one with the same maximum value, it will transmit to one of them.
Patent NZ-531430-A (NZ)
Title: Ascorbic acid derivatives, methods of synthesis and pharmaceutical use thereof
Inventor: RATH MATTHIAS
IPC: C07D405/06
Filed: 2002-08-23
Abstract: Disclosed is a process for producing L-ascorbic acid derivatives, comprising: treating L-ascorbic acid with lysine, wherein the L-ascorbic acid is covalently bound to the lysine; and isolating said L-ascorbic acid derivatives; wherein the L-ascorbic acid is: covalently bound to one lysine or polylysine in the C-6 position of the L ascorbic acid; or covalently bound to the lysine in the C-6 position of the L-ascorbic acid; or covalently bound to one lysine or polylysine in the C-2 position of the L ascorbic acid; or covalently bound to the lysine in the C-2 position of the L-ascorbic acid. Further disclosed is the use of an ascorbyl-lysine derivative of produced by the above process for the preparation of a medicament for the treatment of damage to skin; or for the prevention or retardation of the effects of aging; or for the stabilization of connective tissue; or for the prevention of the degradation of the extracellular matrix in a subject in need thereof.
Patent NZ-534935-A (NZ)
Title: Modified pituitary gland development in offspring from expectant mother animals treated with gene therapy involving growth hormone releasing hormone therapy
Inventor: DRAGHIA-AKLI RUXANDRA
IPC: A61K38/00
Filed: 2003-02-06
Abstract: Disclosed is a method of changing the pituitary lineage or elevating prolactin levels in an offspring from a non-human female subject comprising: delivering a nucleic acid expression construct into cells of the female subject; wherein, the delivering is completed prior to or during a gestation period of the offspring; the nucleic acid expression construct comprises a promoter; a nucleotide sequence; and a 3' untranslated region; wherein the nucleotide sequence encodes a GHRH or a functional biological equivalent thereof; and delivering is completed under conditions wherein expression of the nucleotide sequence results in the changing the pituitary lineage in the offspring.
Patent NZ-537319-A (NZ)
Title: Systems and methods for collecting and distributing gray water
Inventor: AYLWARD PETER G
IPC: E03B1/04
Filed: 2003-07-09
Abstract: A gray water collection and distribution system includes a main drain line, one or more black water sources connected to the main drain line, one or more gray water sources connected to the main drain line and a collection valve located down stream from at least one of the one or more black water sources. The collection valve includes an inlet connected to the main drain line, and an outlet connectable which can be switched to either a black water drain line or a gray water drain line, depending upon which type of water flow is detected.
Patent NZ-538151-A (NZ)
Title: Folding utility knife
Inventor: PING QIU JIAN
IPC: B26B1/02
Filed: 2005-02-09
Abstract: A utility knife comprising a handle and a blade holder. The blade holder is pivotally mounted on the handle for movement from an unfolded position to a folded position. The handle has a space adapted to receive the blade holder when the blade holder is in its folded position. The blade holder includes a main wall and a guard wall mounted together and adapted to receive a blade therebetween and a locking pivotally mounted on the blade holder to lock the blade in place.
Patent NZ-538572-A (NZ)
Title: Non-covalent inhibitors of urokinase and blood vessel formation
Inventor: LEVY ODILE ESTHER
IPC: A61P31/04
Filed: 2001-08-10
Abstract: Disclosed are selected compounds from general formula (I), such as the compound of formula (II). The compounds are used in the manufacture of medicaments for the treatment of conditions ameliorated by inhibiting or decreasing urokinase activity, angiogenesis in a mammal.
Patent NZ-539914-A (NZ)
Title: Novel heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
Inventor: KANOJIA RAMESH M
IPC: C07D493/04
Filed: 2003-11-21
Abstract: Disclosed are heteroatom containing tetracyclic derivatives. The compounds are useful in the treatment and/or prevention of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
Patent NZ-540604-A (NZ)
Title: Safety device with trigger mechanism
Inventor: COCKER ROBIN CRAIG
IPC: A61M5/32
Filed: 2003-11-19
Abstract: A safety device (10), usable in particular with hypodermic needles, and incorporating a trigger mechanism (13) which when activated primes the device to initiate the unsheathing of the needle in use by flexing needle-surrounding legs (16, 17) away from the needle axis; the initial priming and leg-flexing movement being caused by the interaction of an operative portion of the trigger with the legs; characterised by the feature that, when such movement occurs, the operative portion interacts with the legs in a manner which positively latches and retains the operative portion and the legs in engagement.
Patent NZ-542625-A (NZ)
Title: Nanoporous ultrafine alpha-alumina powders and sol-gel process of preparing the same
Inventor: WANG YUHU
IPC: C01F7/442
Filed: 2004-03-31
Abstract: An alpha-alumina powder comprising alpha-alumina particles wherein about 99% of the alpha-alumina particles have a size from about 10 nm to about 100 nm and about 99% of the alpha-alumina particles are within a size distribution of about 10 nm.
Patent NZ-545231-A (NZ)
Title: Antioxidant sensor, methods and compositions
Inventor: MCANALLEY BILL H
IPC: A23L33/00
Filed: 2004-08-25
Abstract: The disclosure relates to an apparatus and method for detecting directly the antioxidant activity of both lipophobic anti-oxidants that uses an oxygen radical sensitive molecule in fluid communication with a sample in a solvent/water/surfactant mixture; wherein the oxygen sensor concurrently detects the effect of both lipophilic and lipophobic anti-oxidants in the solvent/water/surfactant mixture on the oxygen sensor.
Patent NZ-547668-A (NZ)
Title: Taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives
Inventor: DE LUCA GILDA
IPC: A61P35/00
Filed: 2003-10-10
Abstract: Disclosed are taxanes, in particular paclitaxel and docetaxel, covalently bounded to hyaluronic acid or hyaluronic acid derivatives, the process for their preparation and to their use in the field of oncology, in the treatment of autoimmune disorders and restenosis. (62) Divided Out of 540034
Patent NZ-547936-A (NZ)
Title: Cannulated fastener system with screwdriver shank passing through cannulation of bone screw and to rotate screw and having blade on end to commence cutting
Inventor: CICCONE PAUL
IPC: A61B17/56
Filed: 2004-11-24
Abstract: A cannulated fastener system is provided for orthopedic applications that include attaching bone plates to bone. The bone fastener has a cannulation with an inner shape. One or more screwdrivers is provided with a shaft having a shape that matches the cannulation of the fastener to rotationally fix the fastener to the screwdriver. In addition, the screwdrivers have a cutting blade that begins the drilling of a hole for the bone fastener. The screwdrivers may either be for use with a single fastener or have multiple fasteners loaded within a retaining sleeve for automatic or controlled dispensing.