baber/WOPTO huggingface dataset:
Patent DE-69309324-T2 (DE)
Inventor: DE SANTANA GILDETE VITORIA
IPC: B65D41/34
Filed: 1993-01-21
Granted: 1997-07-10
Abstract: A closure cap, for a bottle or similar container having a treaded neck and especially for containing a carbonated beverage, which cap has internal screw threads (5) and at its lower edge a retaining band (8) which is interconnected to the bottom of the skirt (6) of the cap by a rupturable linear portion (11), said retaining band (11) having an annular inwardly directed projection (9), the lower face of which is substantially angled inwardly so as to allow the annular projection (9) to be forced over an annular collar on the neck of the bottle; and wherein the rupturable portion (11) of the skirt (6) has (a) a horizontal interrupted annular rupturable line (11), the interruptions (12) whereof which attach the band to the skirt being substantially smaller than the cut-through segments thereof apart from one interruption (12') which is at least twice preferably two to three times the length of the adjacent segments and (b) a vertically extending rupturable line (13,14) which extends from the lower edge of the band (11) and across said annular projection (9) and terminates adjacent to said longer interrupted segment (12') of the horizontal line; whereby upon turning of the closed cap the band (11) become detached from the cap except at said longer segment (12') and the detached band (7) extends downwardly from the open cap. The threads (5) can have gaps (16) for escape of Co2. The detached band (7) indicates if the container has been opened.
Patent DE-69315186-T2 (DE)
Inventor: DAVIS THOMAS G
IPC: G02B7/04
Filed: 1993-12-20
Granted: 1998-03-19
Abstract: An apparatus for carrying an ophthalmic lens, particularly while the lens is being inspected, including a base member and a well connected to the base member. The well is substantially transparent, and includes a frusto-conical sidewall having a constant slope, and a hemi-spherically shaped bottom portion connected to an extending downward from the sidewall. The bottom portion of the well has curvature that is about 10% larger than the radius of curvature of the ophthalmic lens. <IMAGE>
Patent DE-69321545-T2 (DE)
Inventor: FABRE JEAN-CLAUDE
IPC: C08L95/00
Filed: 1993-08-31
Granted: 1999-06-17
Abstract: Storable dense coated mixes and emulsion-gravels are produced by coating with a mixed emulsion of hard bitumen and soft bitumen. Unexpectedly, these coated mixes have a storability which makes them resemble coated mixes produced with a soft bitumen, but they assume the cohesion which corresponds to the viscosity of the bitumen consisting of the homogeneous mixture of bitumens. The mixed emulsion, preferably cationic, is produced very simply, for example by mixing an emulsion of hard bitumen and an emulsion of soft bitumen. <IMAGE>
Patent DE-69322508-T2 (DE)
Inventor: ALBREKTSSON BJOERN
IPC: A61F2/38
Filed: 1993-05-19
Granted: 1999-07-08
Abstract: PCT No. PCT/SE93/00451 Sec. 371 Date Dec. 14, 1994 Sec. 102(e) Date Dec. 14, 1994 PCT Filed May 19, 1993 PCT Pub. No. WO93/24079 PCT Pub. Date Dec. 9, 1993The invention relates to a joint prosthesis for permanent anchorage in the bone tissue of one of the articulatory parts of a joint in a human body, in particular the femur side of a knee joint, primarily intended to be fitted in one operation only. The prosthesis comprises an attachment part (1), intended to be anchored in the human bone tissue by means of a fixture (8), and an articulation element (2) adapted to fit the attachment part (1). The articulation element is attached to the attachment part by a combination of complementary shapes (27, 28, 33, 34) and snap-action locking means (31).
Patent DE-69323212-T2 (DE)
Inventor: FARACI WILLIAM
IPC: C07D403/04
Filed: 1993-11-03
Granted: 1999-05-27
Abstract: PCT No. PCT/US93/10359 Sec. 371 Date Jun. 14, 1995 Sec. 102(e) Date Jun. 14, 1995 PCT Filed Nov. 3, 1993 PCT Pub. No. WO94/13643 PCT Pub. Date Jun. 23, 1994The pyrazoles and pyzazolopyrimidines of the formula    <IMAGE>  I  wherein R1, R2, R3, R4 and A are as defined herein, have corticotropin releasing factor (CRF) antagonist activity. As such, they are effective in the treatment of a wide range of diseases including stress-related illnesses.
Patent DE-69323497-T2 (DE)
Inventor: KLUGER RONALD
IPC: A61K47/48
Filed: 1993-11-12
Granted: 1999-09-16
Abstract: Hemoglobin is site-specifically crosslinked into its tetrameric form by reaction with a trifunctional reagent which combines electrostatic effects, steric effects and the presence of functional groups so that two of the functional groups react with specific sites on the hemoglobin whilst the third site is left free for reaction with endogenous nucleophilic compounds. A specific example of such a crosslinking reagent is trimesoyl tris(3,5-dibromosalicylate), TTDS, which effects specific crosslinking between the amino groups of lysine-82 on each respective  beta  sub-unit. While the crosslinking reagent TTDS has three available carboxyl groups for the crosslinking reaction, only two so react, leaving one free carboxyl for reaction with exogenous nucleophiles, e.g. to render the hemoglobin product useful as a carrier for nucleophilic compounds through the body's circulatory system.
Patent DE-69326145-T2 (DE)
Inventor: SELA MICHAEL
IPC: A61P37/00
Filed: 1993-06-18
Granted: 2000-04-27
Abstract: Peptides having at least nine amino acid residues each including an amino acid sequence which corresponds to position p200-208 or p262-266 of the human acetylcholine receptor (alpha)-subunit, but differing therefrom by one or more amino acid substitutions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.
Patent DE-69328085-T2 (DE)
Inventor: ANDRIC DRAGISA
IPC: B32B/
Filed: 1993-10-29
Granted: 2000-11-16
Abstract: Security paper comprising a central resinous substrate sheet carrying indicia on one face, with paper sheets permanently laminated to both faces such that the indicia are substantially undetectable when viewed in reflected light and are apparent through the paper sheets when viewed by transmitted light within the visible spectrum.
Patent DE-69328549-T2 (DE)
Inventor: BARD JONATHAN A
IPC: C07H21/04
Filed: 1993-10-29
Granted: 2000-08-24
Abstract: PCT No. PCT/US93/10553 Sec. 371 Date Jun. 15, 1995 Sec. 102(e) Date Jun. 15, 1995 PCT Filed Oct. 29, 1993 PCT Pub. No. WO94/09828 PCT Pub. Date May 11, 1994The invention provides for processes for identifying chemical compounds which specifically bind to a human 5-HT4B having the amino acid sequence of SEQ ID NO: 2.
Patent DE-69329114-T2 (DE)
Inventor: WARD DANIEL
IPC: B01D24/30
Filed: 1993-05-04
Granted: 2001-03-15
Abstract: A deep bed upflow filter (10) for removing suspended solids from an influent stream to provide a clean filtrate, comprising an upright vessel (12) having a vertical axis (14), top and bottom ends (16,18) and contiguous upper (20), lower (22), and intermediate (24) regions between the ends. The upper region contains filtrate (26) up to a first elevation (28) and an outlet (30) for drawing the filtrate out of the vessel. The intermediate region contains particulate filter media (32) for removing the suspended solids from influent moving upwardly through the media as the media, dirtied with solids, moves downwardly into the lower region. The lower region is generally tapered (36) inwardly toward the vessel bottom and contains dirty media (34) that has moved downwardly from the intermediate region. Influent is introduced (44) between the intermediate and lower regions, and the dirty media is collected (46) at the bottom and transported (50) to a regenerative washing compartment (52). A portion of the reject flow (64 ) from the wash compartment is delivered (72,74) to the dirty media in the lower region of the vessel and another portion (72,78) is delivered to the area (46,48,50) where the dirty media is collected and transported. This latter portion is preferably introduced into a collection conduit (46) through a pipe (130) having a concentric inner tube (140) by which air is injected to fluidize and move the mixture of air, dirty media, and reject water in the conduit (46) toward an airlift (48,148).
Patent DE-69404678-T2 (DE)
Inventor: GRENNES TORBJORN
IPC: C08J3/09
Filed: 1994-06-16
Granted: 1998-03-05
Abstract: A thin-walled rubber article with a high tear resistance prepared by dip forming, comprising a polymer blend which comprises 10-75 % by weight styrene-isoprene-styrene (S-I-S) triblock copolymer, 1-90 % styrene-butadiene-styren (S-B-S) triblock copolymer, and 0-25 % by weight styrene-olefin-styrene (S-O-S) triblock copolymer.
Patent DE-69407061-T2 (DE)
Inventor: MYERS ROBERT M
IPC: A61N1/30
Filed: 1994-03-18
Granted: 1998-06-04
Abstract: An iontophoretic agent delivery device having a simplified structure and ease of manufacture. The device utilizes an electrical pathway comprising a source of electrical energy and an output means. The electrical pathway is disposed upon one of the two sides of a flexible, non-conductive substrate (e.g., a film). The output means of the pathway are connected directly or indirectly, e.g., by means of an electrically conductive adhesive tape, to the remaining components of the device such as current distribution members, lead wires, or electrodes. In this arrangement, the circuit is inverted from that of conventional devices. Economical, reel-to-reel methods of manufacturing a one-sided iontophoretic circuit apparatus of the invention are disclosed.
Patent DE-69407592-T2 (DE)
Inventor: WHITEHEAD LORNE
IPC: G01H11/06
Filed: 1994-07-12
Granted: 1998-08-20
Abstract: An electrostatic transducer in which two sheets are separated by a gas-filled gap. The sheets have conductive surfaces for imposing electric fields within the gap when an electrical potential is applied across the sheets. A flexible positioning mechanism between the sheets maintains the gap at a desired time-averaged thickness. The gap is made up of a plurality of thick regions and a plurality of thin regions. Both regions have a total projected area which is a substantial portion of the total area of one of the sheets. The average thickness of the gap in the thick regions is at least ten times greater than the gap's average thickness in the thin regions. The electrostatic field energy of the electric fields is concentrated in the thin regions.
Patent DE-69424056-T2 (DE)
Inventor: SCHMITZ CHRISTOPH JOHANN
IPC: A61F13/514
Filed: 1994-12-29
Granted: 2000-10-26
Abstract: An absorbent article (20) comprises two hook-type fastening members (62) and a loop-type landing member (68) for mechanically engaging with the hook-type members (62). The landing member (64) comprises a section of the backsheet (30) such that a landing member (64) of low bulk is obtained which is easily manufactured and which can be elastically contracted and extended. <IMAGE>
Patent DE-69425577-T2 (DE)
Inventor: HUBBELL A
IPC: A61L31/06
Filed: 1994-10-05
Granted: 2001-04-26
Abstract: Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of the polymeric material adsorbs well to cells or tissue, and the other component of the polymeric material does not adsorb well to tissues. A water-soluble polymer that does not bear charge (polynonion) is used as the non-binding component, and a water soluble polymer that is positively charged at physiological pH (polycation) is used as the tissue binding component. When the bi-functional polymeric material contacts a tissue, the tissue-binding component binds and thus immobilizes the attached non-binding component, which will then extend generally away from the tissue surface and sterically block the attachment of other tissues. The method and compositions are useful in inhibiting formation of post-surgical adhesions, protecting damaged blood vessels from thrombosis and restenosis, and decreasing the extent of metastasis of attachment-dependent tumor cells.
Patent DE-69428952-T2 (DE)
Inventor: FURUYA SHUICHI
IPC: A61K31/505
Filed: 1994-08-24
Granted: 2002-06-27
Abstract: A thienopyrimidie derivative of the formula: <CHEM> wherein each of R<1> and R<2> is hydrogen or an optionally-substituted hydrocarbon residue; R<3> is hydrogen or a group which is bonded through a carbon atom or nitrogen atom; R<4> is an optionally-substituted hydrocarbon residue; W is a chemical bond or a connecting group and n is an integer of 1-3, or a salt thereof has potent endothelin antagonist activity, thus being used for treating or preventing acute renal insufficiency, myocardial infarction, liver insufficiency, angina pectoris, cerebral infarction, sub-arachnoid haemorrhage (SAH), hypertension, renal insufficiency, asthma, variant form of angina, Raynaud's syndrome, pulmonary hypertension, surgery shock, chronic cardiac insufficiency, cardiac hypertrophy, arteriosclerosis, migraine and the like, furthermore, for treating or preventing a hypofunction of an organ (e.g. liver, etc.) caused by its surgery or transplant, insufficient microcirculation, still fruthermore, for preventing restenosis after PTCA.
Patent DE-69430947-T2 (DE)
Inventor: TONDRE L
IPC: C08K3/22
Filed: 1994-01-13
Granted: 2003-03-13
Abstract: A polyester composition, primarily for use as insulation on wires, having improved heat aging properties. The novel compositions comprise a polymeric component comprising: (A) 60 to 95 % of at least one aromatic polyester; (B) 3 to 20 % of at least one aliphatic polyester; and (C) 3 to 20 % of at least one thermoplastic elastomer, the percentages being by weight based on the weight of the polymeric component.
Patent DE-69434328-T2 (DE)
Inventor: MEHTALI MAJID
IPC: A61K39/00
Filed: 1994-01-03
Granted: 2006-03-09
Abstract: New variants (I) of the TAT protein of HIV, or their fragments, contain at least one mutation involving a change in the natural amino acid at positions 38, 40, 41, 45, 47 or 59-72, provided always that amino acids 41 and 47 are not Ala. Also new are (1) DNA fragments (II) encoding (I); (2) expression cassettes contg. (II) under control of expression elements; (3) prokaryotic or eukaryotic cells contg. these cassettes and (4) variant TAT proteins expressed by (II).
Patent DE-69500617-T2 (DE)
Inventor: HAEMMERLIN BERNARD
IPC: B62B5/02
Filed: 1995-12-20
Granted: 1998-03-26
Abstract: The two wheeled hand cart comprises a tubular chassis formed by two longitudinal side members (1,2) connected by two transverse struts (3,7). The side members carry at their front lower ends a loading plate (4). Above these lower ends are a pair of vertical webs (5,6) which support wheels. A main horizontal axle passes through the lower strut (7) on the ends of which are mounted , outside the webs, horizontal parallelogram shaped finned pivots (11,12). The sides parallel to these pivots (13,14) act, during their rotation, as axles (15,16) for the wheels (17,18). At rest, or in the absence of obstacles, the wheel axles are located in the plane vertical with and above the principal axle. When in contact with an obstacle , under the effect of the rearwards pull caused by the cart, the fins tip frontwards around the principal axle, in the direction of the loading plate. The wheels are thus driven frontwards and downwards and can then roll easily upwards along the obstacle. The cart can easily roll up and over obstacles in its path.
Patent DE-69511830-T2 (DE)
Inventor: POOT TEUNIS
IPC: H04N5/44
Filed: 1995-06-22
Granted: 2000-04-13
Abstract: In a method of decoding a letterbox television signal which comprises a wide aspect ratio center part (CP) and upper (BB1) and lower (BB2) black bars located at the respective upper and lower sides of the wide aspect ratio center part (CP), the wide aspect ratio center part (CP) and the black bars (BB1, BB2) together constituting a standard aspect ratio television signal, the black bars (BB1, BB2) conveying additional signals for increasing a vertical resolution of the wide aspect ratio center part, additional signals from the upper black bar (BB1) and a lower half (CP2) of the center part (CP) are stored in a first memory (FM1), and an upper half (CP1) of the center part (CP) and additional signals from the lower black bar (BB2) are stored in a second memory (FM2). Subsequently, the upper black bar additional signals (BB1) and the upper half (CP1) of the center part (CP) are combined (CF) to form an upper half (OP1) of a wide aspect ratio output picture (OP), and the lower black bar additional signals (BB2) and the lower half (CP2) of the center part (CP) are combined (CF) to form a lower half (OP2) of the wide aspect ratio output picture (OP).
Patent DE-69519876-T2 (DE)
Inventor: JONKKA ARVO
IPC: B27L11/00
Filed: 1995-03-15
Granted: 2001-07-26
Abstract: PCT No. PCT/FI95/00139 Sec. 371 Date Aug. 27, 1997 Sec. 102(e) Date Aug. 27, 1997 PCT Filed Mar. 15, 1995 PCT Pub. No. WO96/28287 PCT Pub. Date Sep. 19, 1996A method of increasing the durability of the cutting point (8) of a blade, and a blade. A compression stress (P10) is formed in at least one surface (10 or 6) joining the point (8) of the blade (1) by cold working the blade.
Patent DE-69528385-T2 (DE)
Inventor: SEGAL JEROME
IPC: A61F2/00
Filed: 1995-12-11
Granted: 2003-05-22
Abstract: A vascular dilatation device for enlarging a flow passage in an obstruction in a vessel carrying flowing blood. A flexible cylindrical dilatation member is provided for placement in the obstruction and has first and second ends and an intermediate portion between the first and second ends with an interior flow passage extending therethrough having a diameter and a longitudinally extending central axis. The diameter of the flow passage is variable with movement of the first and second ends relative to each other along the longitudinally extending central axis from a contracted position to an expanded condition. The flexible cylindrical dilatation member is comprised of a plurality of flexible elongate elements each of which extends helically about the longitudinally extending central axis. First and second collars respectively engage the first and second ends of the flexible cylindrical dilatation member to retain the first and second ends in contracted positions. A mechanism is provided for causing relative axial movement of the first and second ends towards each other to cause an intermediate portion of the flexible cylindrical dilatation member to expand to form a rigid cylinder and thereby enlarge the obstruction spaces between the flexible elongate elements at the first and second ends so that blood in the vessel can continue to flow through said first and second ends and through the interior flow passage.
Patent DE-69528982-T2 (DE)
Inventor: NAGASHIMA KAZUFUMI
IPC: C23C16/27
Filed: 1995-08-09
Granted: 2003-08-28
Abstract: A plastic container has a diamond like carbon film 20b formed on the inner surface of the container 20 made of plastic material 20a. The thickness of the diamond like carbon film 20b is within a range from 0.05 to 5 µm. The container 20 coated with the diamond like carbon film can be used for a returnable bottle for beverage.
Patent DE-69530224-T2 (DE)
Inventor: DAVIS S
IPC: B65D81/24
Filed: 1995-12-20
Granted: 2004-02-05
Abstract: Films, containers made of high density polyethylene, and articles made therefrom exhibit, for a given density, improved resistance to water vapor transmission. The high density polyethylenes are produced in a metallocene-catalyzed production process. Alternatively, for equivalent water vapor transmission rates (WVTR) an article formed in accordance with the invention will exhibit improved physical properties, such as dart drop impact, more balanced tear properties and improved machine direction (MD) tear properties. Additionally, these high density polyethylenes show a low level of extractables and an excellent organoleptic profile.
Patent DE-69634300-T2 (DE)
Inventor: BOTH WAYNE
IPC: A61K35/76
Filed: 1996-08-14
Granted: 2005-12-22
Abstract: PCT No. PCT/AU96/00518 Sec. 371 Date Apr. 20, 1998 Sec. 102(e) Date Apr. 20, 1998 PCT Filed Aug. 14, 1996 PCT Pub. No. WO97/06826 PCT Pub. Date Feb. 27, 1997A method of delivering a nucleic acid molecule to a human cell which involves exposing to the cell a viral vector containing a DNA molecule including a nucleic acid sequence encoding the genome of an ovine adenovirus capable of infecting human cells or functionally equivalent nucleic acid sequence or portion thereof and at least one nucleic acid sequence encoding a gene to be expressed in the cell, such that the vector infects the cell and the infected cell expresses the gene.
Patent DE-69635941-T2 (DE)
Inventor: VONBORSTEL REID W
IPC: C07H19/06
Filed: 1996-06-06
Granted: 2006-11-23
Abstract: Treatment of cancer comprises admin. of a pyrimidine nucleoside analogue (I) in at least 1.5 times the normal max. tolerated dose and an acyl deriv. of a non-methylated pyrimidine nucleoside (II). Also claimed is treatment of cancer comprising admin. of an inhibitor of dihydropyrimidine dehydrogenase (III), 5-fluoropyrimidine or 5- fluoropyrimidine nucleoside analogue and (II).
Patent DE-69726602-T2 (DE)
Inventor: MURRAY KENNETH
IPC: A61K39/00
Filed: 1997-10-31
Granted: 2004-09-30
Abstract: Peptides and other molecules which inhibit the assembly of the hepatitis B virus, methods of treatment, and pharmaceutical compositions comprising them.
Patent DE-69732929-T2 (DE)
Inventor: KERWIN JOHN
IPC: F25B9/14
Filed: 1998-07-14
Granted: 2005-08-18
Abstract: A Stirling machine having two pistons coupled to a harmonic crank drive linkage for providing a specified phase relationship between sinusoidal displacements of each piston with respect to a fixed fiducial point. The harmonic crank drive linkage has a primary crankshaft and an eccentric crankshaft mounted internally to the primary crankshaft and coupled via a gear set to counterrotate with respect to the primary crankshaft. The eccentric crankshaft may be cantilevered with respect to the primary shaft, with the pistons of the engine coupled to the eccentric crankshaft externally to the supporting bearings. A flywheel coupled to the eccentric crankshaft provides for operation of the engine with a zero net angular momentum. An intake manifold provides for mixing air and fuel for combustion heating of the engine.
Patent DE-69803041-T2 (DE)
Inventor: ATWOOD G
IPC: G01R27/02
Filed: 1998-03-30
Granted: 2002-07-11
Abstract: An apparatus for performing a polymerase chain reaction may have an assembly, a heated cover, and a computer. The assembly is capable of cycling samples through a series of temperature excursions and the computer controls the process of cycling the samples through the series of temperature excursions. The assembly includes: a sample block that is configured to receive a plurality of sample vials, a plurality of Peltier thermal electric devices, a heat sink, and a memory device that stores data related to the assembly.
Patent DE-69815758-T2 (DE)
Inventor: DEMILLY FRANCOIS
IPC: B60B17/00
Filed: 1998-04-29
Granted: 2004-04-29
Abstract: A railway wheel, comprising a rim connected to a hub by a flange which is less thick in the axial direction than the rim, is made of steel containing less than 0.35% carbon and less than 5% in total of alloying elements has an Ms point above 270 degrees C. During manufacture it is tempered and then heated at over 550 degrees C, so that at least the outer surface of the rim has mechanical properties as follows: Rm=860-960 MPa, Rp 0.2 at least 700 MPa, K1c at least 80 MPa per square m. Also claimed is a wheel of this sort, made of steel containing by weight 0.2-0.24% carbon, 0.9-1.1% manganese, 0.9-1.1% silicon, 1-1.2% chromium and 0.2-0.25% molybdenum, the rest being iron and impurities. The wheel has the mechanical properties listed above which are not affected by braking equivalent to 540 degrees C maintained for one hour.