baber/WOPTO huggingface dataset:
Patent EP-1506313-B1 (EP)
Inventor: VERDIN ERIC
IPC: C12Q1/48
Filed: 2003-05-22
Granted: 2011-01-26
Abstract: The present invention provides methods for identifying agents that modulate a level or an activity of a mitochondrial NAD-dependent deacetylase polypeptide, as well as agents identified by the methods. The invention further provides methods of modulating mitochondrial NAD-dependent deacetylase activity in a cell. The invention further provides methods of modulating mitochondrial function by modulating the activity of mitochondrial NAD-dependent deacetylase.
Patent EP-1550662-B1 (EP)
Inventor: ISOBE Y
IPC: A61P31/12
Filed: 2003-09-26
Granted: 2012-07-04
Abstract: L'invention concerne un médicament topique efficace comme agent antiallergique. Ce médicament topique renferme, comme ingrédient actif, un composé d'adénine représenté par la formule générale (1) [dans laquelle le cycle A désigne un carbocycle aromatique mono- ou bicyclique comportant 6 à 10 éléments ou un hétérocycle aromatique mono- ou bicyclique comportant 5 à 10 éléments contenant un à trois hétéroatomes sélectionnés dans le groupe renfermant zéro à deux atomes d'azote, zéro ou un atome d'oxygène, et zéro ou un atome de soufre ; n désigne un entier compris entre 0 et 2 ; m désigne un entier compris entre 0 et 2 ; R désigne un halogéno, un alkyle (non) substitué, etc. ; X1 désigne de l'oxygène, du soufre, NR1 (R1 désignant de l'hydrogène ou un alkyle), ou une liaison simple ; Y1 désigne une liaison simple, un alkylène, etc. ; Y2 désigne une liaison simple, un alkylène, etc. ; Z désigne un alkylène ; et au moins un des Q1 et Q2 désigne  COOR10 (R10 désignant un alkyle (non) substitué, etc.), etc.] ou un sel de qualité pharmaceutique de ce composé.
Patent EP-1521689-B1 (EP)
Inventor: BRASCHEL VOLKER
IPC: B60T13/66
Filed: 2003-07-10
Granted: 2006-05-03
Abstract: In order to improve an electronic system for a motor vehicle which comprises an electronic controller which is coupled via an electronic communication system to electronic controllers of other electronic systems of the vehicle in order to co-operate through data exchanges with the other electronic systems of the vehicle, wherein electronic sensor devices for controlling and/or regulating operating states of the vehicle detect quantities which are related to the operating states of the vehicle, so as to obtain cost and functional advantages, it is proposed that at least one of the electronic sensor devices be accommodated in one of the electronic controllers.
Patent EP-1569864-B1 (EP)
Inventor: WAUTERS ALBERT
IPC: B67D1/04
Filed: 2003-11-26
Granted: 2011-10-05
Abstract: The apparatus (10) includes a valve assembly mounted around the neck of the keg to regulate the dispensing of beverage from within the keg. The valve assembly has a valve unit that regulates beverage dispensing. A dispensing adaptor is mounted to the valve assembly, and has a hollow arm with an exterior remote end coupled to a tap (14) operable between open and close position. The other hollow arm end is connected to the valve unit. At the tap open position, beverage is allowed to flow through the hollow arm and out of the tap. At the tap close position, beverage is not allowed to flow through the hollow arm. The valve assembly and the keg are set within the housing, during the beverage dispensing. An independent claim is also included for a tap adaptor.
Patent EP-1585743-B1 (EP)
Inventor: BORCHARDT ALLEN J
IPC: C07D401/12
Filed: 2003-12-08
Granted: 2007-05-23
Abstract: L'invention concerne des composés d'indazoles qui modulent et/ou inhibent les maladies ophtalmiques et l'activité de certaines protéines kinases. Lesdits composés et les compositions pharmaceutiques les contenant peuvent induire une transduction du signal des tyrosines kinases et moduler et/ou inhiber ainsi une prolifération cellulaire indésirable. L'invention concerne également l'utilisation thérapeutique ou prophylactique de compositions pharmaceutiques contenant lesdits composés, ainsi que des méthodes de traitement de maladies ophtalmiques ainsi que du cancer et d'autres affections associées à une angiogenèse et/ou à une prolifération cellulaire indésirables, telles que la rétinopathie diabétique, le glaucome néovasculaire, la polyarthrite rhumatoïde et le psoriasis, par administration de quantités efficaces desdits composés.
Patent EP-1556055-B1 (EP)
Inventor: BOURGUIGNON JEAN-JACQUES
IPC: A61P25/18
Filed: 2003-10-30
Granted: 2008-10-29
Abstract: The invention concerns the use of PDE2 inhibitors for treating disorders of the central and peripheral nervous system, a method for therapeutic treatment by administering to an animal said inhibitors. More specifically, the invention concerns novel benzodiazepinone derivatives and their uses in therapeutics more particularly for treating pathologies involving activity of a cyclic nucleotide phosphodiesterase type 2. The invention also concerns methods for preparing same and novel synthesis intermediates.
Patent EP-1565361-B1 (EP)
Inventor: DAIGRE RICHARD
IPC: F16D55/36
Filed: 2003-11-04
Granted: 2012-03-28
Abstract: L'invention concerne un frein de libération à ressort appliqué mécaniquement, à joint dynamique de petit diamètre, intégré dans une roue et dans un pneumatique afin de constituer un petit ensemble utilisé dans les chariots élévateurs, dans les roues de camion, et dans d'autres véhicules industriels.
Patent EP-1537244-B1 (EP)
Inventor: NORDHEIM ALFRED
IPC: C12Q1/68
Filed: 2003-09-08
Granted: 2011-12-28
Abstract: Method for detecting molecules (A), especially peptides, (glyco)proteins, carbohydrates, proteoglycans and/or nucleic acid, that uses a metal compound (I) in presence of at least one reagent (II) that is at least bifunctional, including at least one each of hydrophobic part and reducing part.  An Independent claim is also included for a kit for detecting (A) that contains (II), preferably in the fixing solution.
Patent EP-1562596-B1 (EP)
Inventor: HOELZEMANN GUENTER
IPC: A61K31/4439
Filed: 2003-10-30
Granted: 2006-08-30
Abstract: Novel indole derivatives of the formula (I), in which X, Y, R<SUP>1</SUP>, R<SUP>1'</SUP>, m and n have the meanings indicated in Patent Claim 1, have a strong affinity to the 5-HT<SUB>1A </SUB>and in some cases to the 5-HT<SUB>1D </SUB>receptors. The compounds inhibit serotonin reuptake, exhibit serotonin-agonistic and -antagonistic properties and are suitable as antidepressants, anxiolytics and for the treatment of neurodegenerative diseases
Patent EP-1447276-B1 (EP)
Inventor: SITZLER WOLFGANG
IPC: E06B9/44
Filed: 2004-01-22
Granted: 2006-06-14
Abstract: The winding reel (10) has a winding shaft (11), for reception of the material web (12), formed from a metal tubular profile (13), with at least one longitudinal slot (36) formed in the profile wall (33) for clamping an edge strip (14) of the material web, as in DE 10163699 C1. The profile wall has a longitudinal welding seam (34) which is independent of the longitudinal slot.
Patent EP-1457365-B1 (EP)
Inventor: TRAPP RALPH
IPC: B60H1/00
Filed: 2004-03-10
Granted: 2007-05-16
Abstract: An interior temperature sensor (ITS) (28) fits in a casing (18) in or on a wall (12) adjacent to a motor vehicle's interior (14) and partly borders on the vehicle's interior. A radiation sensor (30) detects the sun's radiation that causes the ITS casing to heat up. A compensating temperature sensor (36) behind the wall is thermally decoupled from the ITS.
Patent EP-1643322-B1 (EP)
Inventor: WINKLER PASCAL
IPC: G04B39/00
Filed: 2004-09-29
Granted: 2010-08-18
Abstract: Lighting device with central symmetry for a dial comprises information display(s); housing for receiving an energy source; and a light source. The dial is arranged in a case that is closed at its top part by a crystal delimited by an external face and by an internal face, and on its bottom part by a back cover delimiting with the dial. The thickness of the crystal decreases regularly from the center to the periphery. Lighting device with central symmetry for a dial comprises information display(s); housing (6) for receiving an energy source (7) that powers the display control mechanism (8); and a light source (15) located in the housing. The dial is arranged in a case that is closed at its top part by a crystal (1) delimited by an external face and by an internal face and on its bottom part by a back cover delimiting with the dial. The thickness of the crystal decreases regularly from the center to the periphery. A cylindrical light guide passes through the center of the dial. One end of the guide is opposite the light source and the opposite end is opposite a reflector with axial symmetry formed in a hollow in the center of the crystal for reorienting the rays from the light source by total internal reflection in the thickness of the crystal, and allowing them to emerge towards the dial when the angle of incidence on the inner face of the crystal is greater than the maximum angle of refraction.
Patent EP-1559505-B1 (EP)
Inventor: PAROZ CEDRIC
IPC: B23Q17/22
Filed: 2004-01-30
Granted: 2006-09-13
Abstract: The process involves determining a mean positioning gap (EP) of a tool (2) with respect to a position (5) by using a mean time gap value (EM) between theoretic and actual durations (D1, D2) of a trajectory of the tool. Operation of a tool actuating device (7) is controlled using the positioning gap (EP). Parameters defining the position (5) of the tool on a predetermined oriented axis (W) in a referential space (3) are corrected. Independent claims are also included for the following: (A) a cutting machine having a technical unit for implementing a positioning gap detecting and calculating process (B) an optical or magnetic medium having a software implementing a positioning gap detecting and calculating process.
Patent EP-1440891-B1 (EP)
Inventor: ROESEL STEPHAN
IPC: B65D5/50
Filed: 2004-01-20
Granted: 2011-05-25
Abstract: A packaging structure for holding an article within an outer container includes a frame having a main portion for receiving the article, and a pair of side legs and a pair of end legs foldably connected to the main portion for supporting the main portion. The main portion includes a series of foldable members, the foldable members in a first group being pivotable about axes extending in a first direction and the foldable members in a second group being pivotable about axes extending in a second direction different from the first direction. In an embodiment, a flexible film may be connected to the side legs of the frame such that, in an unfolded condition, there is slack between the film and the main portion of the frame. An article to be packaged is placed between the film and the main portion, and the side legs are placed in a folded condition, tensioning the film against the article. The packaging structure and the article held therein may be held in place in an outer container.
Patent EP-1582264-B1 (EP)
Inventor: MORGAN SEAN
IPC: B05B1/30
Filed: 2004-04-01
Granted: 2011-08-24
Abstract: A check valve which includes a body adapted at one end to receive a liquid source and at the other end to engage with a spray nozzle and having a bore therethrough, an internal annular recess within the body, the upstream end of which body provides a valve seat, a valve assembly located in the recess and having a valve member having a generally curved end directed towards the seat and bias means to normally hold the member against the seat until the pressure at the inlet reaches a pre-determined minimum.
Patent EP-1590403-B1 (EP)
Inventor: MUENZ XAVER
IPC: C08L63/00
Filed: 2004-01-20
Granted: 2008-08-06
Abstract: Compositions containing at least one liquid epoxy resin, at least one solid epoxy resin, at least one propellant, at least one curing agent and at least one mica-containing filler produce expandable, thermally curable binder systems which may be used without the addition of hollow glass beads for the production of stiffening and reinforcing laminates and for the production of stiffening and reinforcing moldings. Said laminates according to the invention are suitable for the stiffening and reinforcing of components, in particular in the automotive industry, such as car body frames, doors, boot lids, engine bonnets and/or roof parts. In addition, the mouldings that may be produced from said binders are suitable for the stiffening and reinforcing of hollow metal structures, in particular of hollow car body parts such as body frames, body supports and posts or doors in the automotive industry.
Patent EP-1599089-B1 (EP)
Inventor: WANG MING BO
IPC: A01H1/00
Filed: 2004-02-19
Granted: 2011-10-12
Abstract: Methods and means are provided to increase the efficiency of gene silencing when using dsRNA sequences which have a stem length shorter than about 200 base pairs by providing chimeric genes encoding such dsRNA sequences with a promoter recognized by DNA dependent RNA polymerase III comprising all cis-acting promoter elements which interact with DNA dependent RNA polymerase III.
Patent EP-1602144-B1 (EP)
Inventor: GABRIEL ROLAND
IPC: H01P1/04
Filed: 2004-02-19
Granted: 2008-03-12
Abstract: An improved radio-frequency or network connection including a basic module having two or more basic signal coupling surfaces, and a network module having two or more network signal coupling surfaces. The basic module has a basic ground coupling surface, and the network module has a network ground coupling surface. In the operating state, the basic ground coupling surface is capacitively RF coupled to the network ground coupling surface, and is aligned parallel thereto.
Patent EP-1602070-B1 (EP)
Inventor: WEBER MARTIN
IPC: G06T7/00
Filed: 2004-03-08
Granted: 2009-12-16
Abstract: A method is provided of processing digital image data representing an image of an object to determine data representing a boundary for said object, the method comprising: inputting said image data; initializing a level set function representation of an interface for approximating said boundary; determining a motion of said interface subject to a combined cost function comprising a first cost comprising a signed distance constraint on said interface level set function representation and a second cost comprising a measure of said interface responsive to a density or metric of said image; modifying said level set function representation of said interface in accordance with said determined motion; repeating said determining and modifying such that said interface converges on said boundary; and determining boundary data representing said boundary from said converged level set function interface representation.
Patent EP-1615893-B1 (EP)
Inventor: COE JOTHAM WADSWORTH
IPC: A61P25/00
Filed: 2004-04-02
Granted: 2009-11-18
Abstract: The subject invention relates to 2-azabicyclo[3.3.1]nonane derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by opioid receptors. The subject invention also particularly relates to using such derivatives to treat certain disorders and conditions, for example irritable bowel syndrome, drug addiction, including alcohol addiction, depression, anxiety, schizophrenia and eating disorders, among others, as are more fully described herein.
Patent EP-1639119-B1 (EP)
Inventor: GLUECK SILVIA
IPC: C12N9/90
Filed: 2004-06-17
Granted: 2010-04-21
Abstract: The present invention relates to a method for the microbiological isomerization of alpha-hydroxycarboxylic acids using an alpha-hydroxycarboxylic acid racemase, the enzymes used for this method and microorganisms which express a suitable racemase activity, a screening method for microorganisms with alpha-hydroxycarboxylic acid racemase activity, the nucleic acid sequences encoding this enzyme, expression vectors, recombinant microorganisms which express this racemase, and methods for the production or isolation of a protein with alpha-hydroxycarboxylic acid racemase activity.
Patent EP-1640372-B1 (EP)
Inventor: YOSHIMOTO T
IPC: C07D319/20
Filed: 2004-06-23
Granted: 2012-08-01
Abstract: By using a charge-transporting thin film which is made of a charge-transporting varnish containing, as an electron-acceptor material, a 1,4-benzodioxane sulfonic acid compound represented by the formula (1) below especially in an OLED device or a PLED device, there can be realized excellent EL device characteristics such as low driving voltage, high luminous efficiency and long life.
Patent EP-1656122-B1 (EP)
Inventor: HORSTMANN MICHAEL
IPC: A61P25/16
Filed: 2004-08-14
Granted: 2009-10-28
Abstract: The transdermal pharmaceutical preparations for the treatment of Parkinson's disease contain a combination of at least two active substances selected from the following groups of active substances: dopamine agonists and L-dopa, monoamine oxidase inhibitors, anticholinergics, NMDA-receptor antagonists, sympathomimetics; at least two of the said active substances being members of different active substance groups.
Patent EP-1673637-B1 (EP)
Inventor: HACKNER MICHAEL
IPC: G01R31/327
Filed: 2004-09-16
Granted: 2007-02-14
Abstract: A switch device includes a switch to be tested with a first terminal and a second terminal as well as a control terminal for controlling a resistance between the first terminal and the second terminal. Furthermore, the switch device includes a resistor as well as means for providing a measuring current across the resistor into the first terminal of the switch to be tested, wherein the control terminal and the first terminal of the switch to be tested are coupled in electrically conductive manner. Furthermore, the switch device includes means for sensing a voltage present due to the measuring current between the control terminal and the second terminal of the switch to be tested, wherein the voltage refers to an operability of the switch to be tested. With the switch device, in particular a greater number of potentially occurring errors of the switch to be tested can be detected as opposed to conventional switch devices.
Patent EP-1651247-B1 (EP)
Inventor: OFT MARTIN
IPC: C12N5/09
Filed: 2004-07-16
Granted: 2008-09-10
Abstract: Provided are methods of treatment for tumors. In particular, provided are methods of using of a cytokine molecule and its receptor.
Patent EP-1670767-B1 (EP)
Inventor: SCHLOEMER GEORGE
IPC: C07D223/14
Filed: 2004-09-27
Granted: 2011-08-24
Abstract: L'invention concerne un procédé efficace permettant d'effectuer la résolution d'une amide narwedine, et la synthèse de galantamine.
Patent EP-1675667-B1 (EP)
Inventor: BASHAR REZA
IPC: G01N33/18
Filed: 2004-09-30
Granted: 2008-07-16
Abstract: A device for applying an axial compressive force to a fluid contamination detection system comprising a cup joined by a frangible connection to a filter ring, the force being sufficient to break the frangible connection and collapse a portion of the ring into the cup without damaging the ring. The device includes a stop element and a platform and an actuating mechanism for reciprocally moving the platform relative to the stop element. In a first position, the distance between the platform and the stop element is greater than the axial length of the detection system when the cup and the filter ring of the funnel are connected to each other, and in a second position, the distance between the platform and the stop element is less than the axial length of the detection system when the cup and the filter ring of the funnel are connected to each other.
Patent EP-1700445-B1 (EP)
Inventor: LAU SAMUEL
IPC: H04W80/04
Filed: 2004-10-19
Granted: 2010-04-28
Abstract: Methods and apparatus are disclosed for implementing a speed sensitive mobile network device (e.g., Mobile Router). The speed of the mobile network device is detected. The values of one or more operating characteristics of one or more interfaces of the mobile network device are ascertained, where the values correspond to the speed of the mobile network device. One of the interfaces having a desired set of values of the operating characteristics at the speed of the mobile network device is then selected.
Patent EP-1708947-B1 (EP)
Inventor: PETERS ERWIN
IPC: B65H67/08
Filed: 2004-12-29
Granted: 2007-11-14
Abstract: L'invention concerne un dispositif servant à détecter un fil lors de la saisie d'extrémités de fil (21) dans un tube d'aspiration (17) à écoulement d'air. Le dispositif selon l'invention comprend un dispositif de capteur (22) constitué d'un émetteur (31) et d'un récepteur (32) et placé sur une machine textile produisant des bobines croisées. Un champ de mesure (26) est formé entre l'émetteur (31) et le récepteur (32) et le tube d'aspiration présente une courbure dans la zone du champ de mesure (26). Le champ de mesure (26) est placé à proximité du plus petit rayon du tube d'aspiration (17) qui présente une cavité (27) orientée dans le sens d'écoulement du tube d'aspiration (17) pour la réalisation du champ de mesure (26). Le tube d'aspiration (17) présente, en amont et en aval du champ de mesure (26), une courbure telle que le fil détecté à l'intérieur de la cavité (27) est tendu de façon à s'écarter au moins partiellement du fond de la cavité (27) dans le champ de mesure (26). Il est ainsi possible de détecter le fil de manière simple et sûre.
Patent EP-1692093-B1 (EP)
Inventor: BIADATTI THIBAUD
IPC: C07D213/79
Filed: 2004-12-06
Granted: 2008-11-19
Abstract: Novel ligand compounds having the structural formula (I): in which: Ar is a radical selected from among the radical of formulae (a) to (c) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, or, alternatively, into cosmetic compositions.
Patent EP-1820053-B1 (EP)
Inventor: ALDEGHI ROBERTO
IPC: G02B6/42
Filed: 2004-12-06
Granted: 2011-04-20
Abstract: Point-to-point link for the transmission of digital signals includes two opto-electronic conversion apparatuses and an optical cable including at least one optical fiber having two terminal portions, each opto-electronic conversion apparatus including an opto-electronic device optically coupled to a respective terminal portion between the two terminal portions of the at least one optical fiber, wherein at least one of the two opto-electronic conversion apparatuses is adapted to keep the respective terminal portion of the optical fiber in bent position with a bending radius R, where 1.5 mm<=R<=2.5 mm, and to keep the respective opto-electronic device optically coupled to the bent terminal portion in order to allow the transmission of the digital signals between the optical fiber and the at least one of the two opto-electronic conversion apparatuses; and at least the bent terminal portion of the at least one optical fiber is such as to satisfy the following relationship r/R<0.07*n/(35+n), where n is the stress corrosion susceptibility factor and r is the radius of the cladding of the optical fiber.
Patent EP-1625484-B1 (EP)
Inventor: HILLMAN ROBERT ALLEN
IPC: G06F/
Filed: 2004-02-24
Granted: 2009-09-23
Abstract: The fault-tolerant or self-correcting computer system is disclosed. The computer system that is provided with various sets of protections against failures that may be caused by space radiation, for example. Improved reliability of the system is achieved by scrubbing of the components on a regular schedule, rather than waiting for an error to be detected. Thus, errors that may go undetected for an extended period are not allowed to propagate and further damage the system. Three or more processors are provided to operate in parallel, and a controller is provided to receive signals from the processors and, using a voting logic, determines a majority signal value. In this manner, the controller can detect an error when a signal from one of the processors differs from the majority signal. The system is also provided with a scrubbing module for resynchronizing the processors after a predetermined milestone has been reached. The milestone may be a predetermined time interval or any other event that may be defined by a user.