baber/WOPTO huggingface dataset:
Patent RU-2664478-C2 (RU)
Title: Способ получения культуральной ростовой добавки на основе лизата тромбоцитов человека
Inventor: SERGEEVA NATALYA SERGEEVNA
IPC: C12N5/071
Filed: 2017-08-18
Granted: 2018-08-17
Abstract: Изобретение относится к области клеточной биологии и биотехнологии, в частности к получению культуральной ростовой добавки для культивирования опухолевых клеток. Способ включает нормирование образца тромбоцитарной массы (ТМ) по содержанию тромбоцитов путем центрифугирования ТМ при 3130 g в течение 40 минут при 20°C и ресуспендирование осадка в супернатанте заданного объема до концентрации тромбоцитов 1,75×10клеток/мл, 3-кратный температурный лизис тромбоцитов путем замораживания на сутки до -80°C и размораживания при +37°C. Далее осуществляется осаждение клеточного дебриса путем центрифугирования при 3130 g, 40 минут, 20°C, сбор супернатанта, микроскопический контроль (×200) на наличие в поле зрения не более 3-х фрагментов тромбоцитов, стандартизация путем пулирования равных по объему образцов, полученных из ТМ не менее 12 доноров обеих тендерных групп, далее центрифугирование пулированного ЛТ при 3130 g, 40 минут, 20°C и фильтрация образца на фильтрах 0,45 мкм и 0,22 мкм, наконец, разливание по аликвотам требуемого объема и лиофилизация. Изобретение позволяет осуществить больший прирост опухолевых клеток линии НТ-29, MCF-7 и MG-63 и сходный прирост опухолевых клеток линии HCT-116 и HEp-2. 7 ил., 9 табл., 6 пр.
Patent RU-2742353-C2 (RU)
Inventor: PARRISH SCOTT K
IPC: A01P13/00
Filed: 2016-02-05
Granted: 2021-02-05
Abstract: Изобретение относится к сельскому хозяйству. Настоящее изобретение включает композицию концентрата гербицида - концентрат и композицию гербицида для нанесения, способ получения и применения этих композиций. Изобретение позволяет повысить эффективность борьбы с сорняками. 4 н. и 27 з.п. ф-лы,   3 ил., 4 табл.
Patent RU-2730996-C2 (RU)
Title: Системы установки и извлечения имплантата
Inventor: SMIT DZHEJ S
IPC: A61F2/02
Filed: 2016-06-02
Granted: 2020-08-26
Abstract: Группа изобретений относится к медицине. Система установки имплантата содержит установочный инструмент и установочную направляющую. Установочный инструмент содержит рукояточную часть и установочную канюлю, имеющую длину, проксимальный конец, выполненный рядом с рукояточной частью, и дистальный конец, противоположный проксимальному концу. Установочная канюля выполнена с возможностью доставки имплантата внутрь ткани пациента через разрез в коже пациента на месте имплантации. Установочная направляющая содержит первую поверхность, выполненную с возможностью расположения рядом с поверхностью кожи пациента на месте имплантации, и ориентирующую трубку, проходящую под первой поверхностью и содержащую проксимальный конец, выполненный с возможностью приема дистального конца установочной канюли, дистальный конец, отстоящий от проксимального конца на первое расстояние, и продольную среднюю ось, расположенную относительно первой поверхности на втором расстоянии, под углом или на втором расстоянии и под углом. Установочная направляющая выполнена с возможностью направления установочной канюли в ткани для выполнения установки имплантата на заданную глубину установки под наружной поверхностью кожи пациента, так что обеспечена установка противоположных концов имплантата по существу на одну и ту же заданную глубину. Установочная канюля выполнена с возможностью перемещения внутри рукояточной части или рядом с ней относительно рукояточной части. Способ установки имплантата включает обеспечение вышеуказанной системы установки. Изобретения обеспечивают установку имплантата на любую заданную глубину под наружной поверхностью кожи. 2 н. и 12 з.п. ф-лы, 3 пр., 6 табл., 15 ил.
Patent RU-2721149-C2 (RU)
Title: Gel-forming fluids and methods of their use
Inventor: LIM SYUENN
IPC: E21B43/27
Filed: 2016-10-14
Granted: 2020-05-18
Abstract: FIELD: drilling of wells.SUBSTANCE: invention relates to acidification of a subterranean formation through which a wellbore extends. Method of acidifying a subterranean formation through which a wellbore passes, comprising steps of pumping into a wellbore at pressure below pressure, wherein cracks are formed in the subterranean formation, treating a fluid medium having a first viscosity and containing an aqueous acid solution and a gelling agent of the reduced structural formula, creation in said underground formation of at least one cavity under treatment of fluid medium and exposure to second viscosity of treatment fluid medium greater than first viscosity. Invention is developed in dependent items of the formula.EFFECT: technical result is higher efficiency of treatment of underground formation.10 cl, 5 dwg, 6 tbl, 5 ex
Patent RU-2732270-C2 (RU)
Title: Laminated packaging material and packaging containers made from it
Inventor: TOFT NILS
IPC: B32B7/022
Filed: 2016-11-25
Granted: 2020-09-14
Abstract: FIELD: packaging industry. 
     SUBSTANCE: invention relates to a method of producing laminated cellulose-based material for packaging liquid or semi-liquid food products. Laminated packing material has a main layer of material of paper, cardboard or other cellulose-based material, most internal heat-sealable and liquid-impermeable layer of thermoplastic polymer is intended for contact with packaged food product, as well as a barrier layer laminated between the base layer and the innermost layer. 
     EFFECT: invention provides a cost-effective laminated packaging material based on cellulose, having sufficient mechanical stability, as well as improved properties of the barrier and integrity, which would satisfy the need in cardboard laminated packing materials for liquid. 
     13 cl, 2 tbl, 8 dwg
Patent RU-2760681-C2 (RU)
Title: Pharmaceutical preparation
Inventor: LO DEREK
IPC: C07D403/12
Filed: 2017-05-25
Granted: 2021-11-29
Abstract: FIELD: pharmaceuticals. 
     SUBSTANCE: invention relates to pharmaceutical compositions containing particles produced by spray drying of 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidine-2-yl)piperazine-1-yl)phenyl)-2-oxacetamide particles, as well as an application of the pharmaceutical compositions for prevention or treatment of a fungal infection. 
     EFFECT: pharmaceutical compositions based on 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidine-2-yl)piperazine-1-yl)phenyl)-2-oxacetamide exhibiting antifungal properties are produced. 
     30 cl, 3 dwg, 1 tbl, 5 ex
Patent RU-2746216-C2 (RU)
Inventor: Kejbal Natalya Aleksandrovna
IPC: C08K13/02
Filed: 2018-12-10
Granted: 2021-04-08
Abstract: FIELD: automotive, oil and rubber industries. 
     SUBSTANCE: invention relates to a fire-resistant rubber compound and can be used in the automotive, oil and rubber industries. Technical result is achieved by the fact that a fire-resistant rubber compound containing synthetic isoprene rubber, sulfur, zinc oxide, stearic acid and carbon black, and additionally contains altax, diphenylguanidine and a modifying additive - a phosphate-containing oligomer obtained by interaction of dimethylphosphite, epoxy resin ED-20 and aniline, taken in a mass ratio of 1: 2.5: 0.75, with the following ratio of components, pts. wt.: synthetic isoprene rubber 100.0, sulfur 1.0, altax 1.0, zinc oxide 5.0, stearic acid 1.0, diphenylguanidine 3.0, carbon black P-324 50.0, phosphate-nitrogen-containing oligomer 3.0-7.0. 
     EFFECT: improvement of strength properties of vulcanizates of a fire-resistant rubber compound. 
     1 cl, 2 tbl
Patent RU-2744676-C2 (RU)
Inventor: Marinichev Vadim Evgenevich
IPC: B29C63/36
Filed: 2019-03-13
Granted: 2021-03-15
Abstract: FIELD: municipal services; reclamation; oil and gas industry. 
     SUBSTANCE: invention refers to sanitation of pipelines. Claimed method widens the range of equipment. Method of pipeline sanitation by coating on its inner surface includes introduction into a clean pipeline of a hose and heat-resistant hoses, sleeve is pressed against pipeline wall by pressure of water or air with subsequent polymerisation of polymer binding hose by hot water or steam. Sleeve is made using nonwoven fabric, reinforced with glass-woven fabric and impregnated with polymer binder with possibility of polymerisation by hardening hardeners. Process is started with installation of mounting tower into pipeline, to which sleeve is attached. Hose is turned into the pipeline cavity under pressure of water; at the same time as the hose tail passes into the pipeline cavity heat-resistant hoses are laid. Polymerisation of polymers impregnating the sleeve is carried out by circulating hot water or steam on heat-resistant hoses until temperature inside the sleeve is preferably 90 °C, with further heating of the cavity inside the sleeve within the specified temperature to 8 hours and cooling of the sleeve cavity by circulation of cold water along heat-resistant hoses for at least 24 hours. 
     EFFECT: task for solution of which is creation of invention consists in simplification of technology of pipeline restoration and expansion of technological capabilities of the method. 
     9 cl, 1 dwg
Patent RU-2744253-C2 (RU)
Title: Фильтрующий элемент
Inventor: HEGMANN MARTIN
IPC: B01D29/21
Filed: 2017-10-11
Granted: 2021-03-04
Abstract: Изобретение относится к фильтрующему элементу, сконструированному в виде сменного элемента. Кроме того, изобретение относится к устройству для приема с возможностью замены такого фильтрующего элемента и к способу изготовления из целлюлозы фильтрующей среды для такого фильтрующего элемента. Фильтрующий элемент (3) выполнен в виде сменного элемента, фильтрующая среда (59) которого, выполненная в виде полого тела и расположенная между двумя запирающими элементами, в частности в форме торцевых крышек (13, 19), выполнена гофрированной с отдельными складками, причем фильтрующая среда (59) содержит фильтрующий материал из целлюлозы, при этом предусмотрен фильтр твердых частиц с дополнительным фильтрующим материалом (69), и между двумя фильтрующими средами (59, 69) расположена проницаемая для текучей среды опорная труба (71), состоящая из целлюлозы фильтрующая среда (59) покрыта фильтром (69) твердых частиц, причем на стороне целлюлозной фильтрующей среды (59), направленной от указанной трубы, предусмотрена дополнительная опорная труба (63). Изобретение обеспечивает фильтрующий элемент, который при фильтрации текучих сред, содержащих водно-масляные эмульсии, обеспечит особенно эффективное отделение воды, а также будет отличаться эксплуатационной надежностью и оптимальными затратами на изготовление. 2 н. и 10 з.п. ф-лы, 6 ил.
Patent RU-2762059-C2 (RU)
Inventor: VOORS ADRIAAN
IPC: A61P9/04
Filed: 2017-12-18
Granted: 2021-12-15
Abstract: Изобретение относится к биотехнологии. Представлено применение антитела против адреномедуллина (ADM), или фрагмента антитела против адреномедуллина, или анти-ADM не-Ig каркаса, где указанное антитело против ADM, или фрагмент антитела против ADM, или анти-ADM не-Ig каркас связывается с N-концевой частью. Изобретение эффективно применяется в  терапии гиперемии у пациента. 9 з.п. ф-лы, 21 ил., 11 табл., 10 пр.
Patent RU-2757685-C2 (RU)
Title: Composite material and composite product
Inventor: MAYES DUNCAN
IPC: C08L97/00
Filed: 2018-02-01
Granted: 2021-10-20
Abstract: FIELD: composite materials.SUBSTANCE: composite material contains at least 20% (wt.) of a cellulose material, at least 1% (wt.) and less than 20% (wt.) of a copolymer of a styrene maleic anhydride, and from 5% to 50% (wt.) of an impact-resistant polystyrene. The described cellulose material is thermally modified as a result of heat treatment at a temperature in the range of 160 to 250°C, preferably in the range of 200 to 230°C, at atmospheric pressure, or at a temperature greater than 120°C, at elevated pressure. The thermally modified cellulose material, the impact-resistant polystyrene and the copolymer of a styrene maleic anhydride are supplied into an extruder, and a composite product is extruded.EFFECT: strength and stiffness characteristics are improved, creeping of the cellulose fibre contained in the composite material is reduced.13 cl, 6 tbl
Patent UA-72495-C2 (UA)
Title: N-[2-hydroxy-3-(1-pyperidinyl)propoxy]pyridine-1-oxide-3-carboxyimidoylchloride, a pharmaceutical composition and a method for treatment of insulin resistance with use thereof
IPC: A61K31/44
Filed: 2000-02-24
Abstract: The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts thereof, pharmaceutical compositions containing the same, the use of these compounds in the treatment of pathological insulin resistance, and for the treatment of pathological conditions associated therewith, for the treatment of pathological insulin resistance, and the treatment of pathological conditions associated therewith, by simultaneous treatment and prevention of diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy and/or with simultaneous increasing pathologically decreased peripheral neuroregeneration caused by diabetes and methods of treatment.
Patent UA-66927-C2 (UA)
Title: 3-deoxy-desmycosin derivatives and a method for the preparation thereof
Inventor: LOPOTAR NEVENKA
IPC: C07D321/00
Filed: 2000-05-02
Abstract: The present invention relates to derivatives of 3-deoxy desmycosin of formula I, wherein, starting from triply protected desmycosin, there are performed an oxidation at C-3 in the first step and then, optionally, a hydrogenation of double bonds and an epoxidation followed by a reductive opening of the oxirane ring. The present invention also relates to derivatives of 3-deoxy-desmycosin of formula II, wherein in the first step triacetyl desmycosin is hydrogenated and then, via an intermediate mesylate, it is convened to a 2,3-didehydro derivative; or 2,3-didehydro-desmycosin is subjected to epoxidation reactions followed by a reductive opening of the oxirane ring.
Patent UA-74029-C2 (UA)
Title: Method for assembly of ship hulls of light alloys and slip-bed for its implementation
Inventor: LAPOCHKIN EDUARD VIKTOROVYCH
IPC: B63B73/10
Filed: 2003-07-03
Abstract: Invention relates to the shipbuilding, in particular, to the technology of assembly of ship hulls of light alloys. The method of hull assembly of light alloys consists in preliminary assembly and welding of separate blocks of hull with subsequent assembling and welding of these blocks of the hull as a whole. At hull assembly and welding the hull units the parts, assemblies and sections are used of increased overall dimensions in comparison with their theoretical sizes for the amount of expected linear welding deformation. At assembly and welding of hull units and of the hull as a whole the preliminary turning of some sections of units and hull areas is used, accordingly, for an angle equal in value, but with opposite sign of expected angular elastic welding deformation of the hull. In this case, the slip-bed in the form of rigid steel three-dimensional structure is used, on which transverse and longitudinal steel patterns are rigidly fixed. Slip-bed is divided along the hull length into two or more separate sections with their hinged interconnection. The actual linear dimensions of the working edges of the patterns of each section of slip-bed and distance between them are increased for the amount of expected linear welding deformation of the hull. The working edges of the transverse patterns of each section of slip-bed in the onboard sections are executed with a turning with respect to appropriate areas of theoretical frames for an angle equal in value, but with opposite sign to the angle of the expected angular elastic welding deformation of the hull. Technical result consists in obtaining of hull of ship from light alloys after its assembly and welding with overall dimensions and the form more accurately corresponding to its theoretical drawing, and also in reduction of the values of residual internal stresses appearing in the links of the hull under thermal action on them during welding.
Patent UA-78964-C2 (UA)
Title: Method for rolled metal production
Inventor: BILYI OLEKSII PETROVYCH
IPC: C21D8/00
Filed: 2005-09-29
Abstract: The invention relates to the field of ferrous metallurgy. A method for rolled metal production involves smelting of steel of the following chemistry (wt. %): C - 0.03-0.15, Mn - 0.8-1.8, Si - 0.1-0.6, Ti - 0.005-0.05, Cr - 0.01-0.03, Ni - 0.01-0.03, Ca - 0.0005-0.0015, N - 0.003-0.012, Cu - 0.01-0.3, Al - 0.01-0.07, S - 0.001-0.015, P - 0.005-0.03, Fe - the rest, uninterrupted pouring out of it into the slabs, cooling of the slab in the temperature interval of 900 - 100 DEGREE C with the rate of 5-25 DEGREE C/hour, their austenitizing, preliminary deformation with the wringing out degree for the passage which is not less than 8 - 20 %, which is finished in the temperature interval of 1050 - 960 DEGREE C, the final deformation with the totalwringing out degree of 50-80 % in the temperature interval of 660 - 950 DEGREE C, at that between the preliminary and final deformation colling of the rolled metal at the rate of 0.5-8.0 DEGREE C/s, colling of the obtained rolled metal to the temperature of 650 - 350 DEGREE C after the final deformation at the rate of 0,5-8,0 DEGREE C/s, final rolled metal cooling to the temperature of 200 - 10 DEGREE C at the rate of 1-20 DEGREE C/hour are carried out. The invention allows to obtain the rolled metal, which has high value of durability, plasticity and cold resistance after the treatment.
Patent UA-80656-C2 (UA)
Title: Pattern for vacuum molding
Inventor: SHYNSKYI OLEH YOSYPOVYCH
IPC: B22C7/00
Filed: 2006-09-27
Abstract: The invention relates to the foundry, in particular, to solid and lost patterns for vacuum molding. A pattern consists of a material which is easily moved away, the pattern has cavities in the form of channels which penetrate a runner and an air hole. The channels are connected with the surface of the pattern and from the side of the surface of pattern are closed with gas-permeable vents capable of holding sand. Technical result: simplifying of removal of pattern prior to or during pouring of metal.
Patent UA-89189-C2 (UA)
Title: Method for color introduction of images
Inventor: DIADYK DMYTRO FEDOROVYCH
IPC: H04N1/60
Filed: 2006-12-25
Abstract: A method for introduction of a color image relates to automatics and computation engineering, and also to information processing and display systems. The method consists in: image matrixes are factorized to three matrixes of color components with NxM size (red, green and blue). An algorithm of finding imaging color components is performed using algorithm of transformation consisting of three successive approximations which are performed in wherever sequence. Color component U' is calculated, which determines preference of saturation for red color over green color for each pixel; a value in positive aria according to the curtain expression is formed. A color component V' is calculated, which determines preference of saturation of blue color over green color for each pixel and a value in positive aria in accordance with the curtain expression is formed. Weil finding Y' brightness, index is determined for every pixel in accordance with the curtain expression. Matrixes of color components Y', U' and V' are formed, properties of which allows them to be compact presented using breakeven coding. The technical result is reducing entropy of brightness without increasing computational complexity of algorithm.
Patent UA-87562-C2 (UA)
Title: Housing for mower culler bar of disk mower (variants), method for making thereof and disk mower
Inventor: WALTER RENE
IPC: A01D34/00
Filed: 2006-01-03
Abstract: The invention relates to a method of producing a housing for a mower culler bar and to the housing thus produced. The invention is characterised in that it comprises the following successive steps consisting in: forming the upper plate (1) and the lower plate (3) of the housing; assembling the formed upper plate (1) and the formed lower plate (3) by means of welding in order to form a casing (6); and cutting holes (7) into the casing (6) using a laser beam, said holes being intended to receive the disc bearings and the intermediary drive pinions.
Patent UA-88816-C2 (UA)
Title: Method for extraction-photometric determination of dinitrobensoic acid
Inventor: BASEL YAROSLAV RUDOLFOVYCH
IPC: G01N31/22
Filed: 2008-01-02
Abstract: Method for extraction-photometric determination of dinitrobenzoic acid that includes obtaining ion associate of dinitrobenzoic acid with organic base dye 1,3, trimethyl-2-[(1E,3E)-5-(1,3, trimethyl-2, dihydro-1Н-2-indol-1, 3-pentadienyl]-3,3a-dihydro-2Н-indolii iodide, its extraction with benzene and following photometering of extractons, and bringing to ionic associate is carried out at concentration of dye 0,0001mol/l and medium acidity рН 3-6.
Patent UA-85025-C2 (UA)
Title: method of impregnation of wood
Inventor: ARYNKIN SERHII MYKHAILOVYCH
IPC: B27K3/00
Filed: 2008-03-03
Abstract: A method of impregnation of wood includes evacuation at stages of preliminary impregnation and post-impregnation, and also at the stage of impregnation, which is achieved under action on it of excess pressure. Impregnation is conducted by steps that grow to 30 atm., with stages of 5 atm. each, with holding at each stage during 20-30 minutes, by pulse pressure with amplitude of pulsation of 2 atm. and with frequency up to 100 oscillations per minute, which is created by dosing pump.
Patent UA-98449-C2 (UA)
Title: Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors
Inventor: RODGERS JAMES D
IPC: A61P35/00
Filed: 2006-12-12
Abstract: The present invention provides heteroary] substituted pyrrolo[2,3-b]pyridines (I) and heteroaryl substituted pyrro]o[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
Patent UA-94734-C2 (UA)
Title: THERAPEUTIC ANTIBODIY WHICH BINDS TO b-AMYLOID PEPTIDE
Inventor: BURBIDGE STEPHEN ANTHONY
IPC: C07K16/18
Filed: 2007-03-27
Abstract: The invention relates to an antibody that binds to human β-amyloid peptide, a pharmaceutical composition comprising thereof and use of a therapeutic antibody in the manufacture of a medicament for the treatment of a β-amyloid peptide-related disease.
Patent UA-94448-C2 (UA)
Title: External antifungal pharmaceutical composition
Inventor: KOBAYASHI HIROKAZU
IPC: A61K31/4178
Filed: 2006-10-02
Abstract: An external pharmaceutical composition characterized by containing 1) luliconazole of the following structural formula (I) and/or its salt and 2) one or two or more members selected from among N-methyl-2-pyrrolidone, propylene carbonate and crotamiton.