baber/WOPTO huggingface dataset:
Patent EP-0559538-B1 (EP)
Inventor: EMONDS-ALT XAVIER
IPC: A61P1/00
Filed: 1993-03-01
Granted: 2000-05-17
Abstract: The subject of the present invention is quaternary ammonium salts of formula: <IMAGE>  in which:   - J represents either an Ar-CXX'-CX" group or an Ar-(CH2)x CX1 group in which:   . Ar represents an optionally substituted phenyl; a cycloalkyl; a pyridyl or a thienyl;   . X represents hydrogen; . X' represents hydrogen or is combined with X" below to form a carbon-carbon bond or else X and X' together form an oxo group;   . x is zero or one; . X1 represents hydrogen (x=0), a hydroxyl, an alkoxy, an acyloxy, a carboxyl, a carbalkoxy, a cyano, a carbamoylalkyl, a mercapto or an alkylthio;     - Q represents an alkyl group or a benzyl group;   - A represents an anion;   - m is 2 or 3; - Ar' represents an optionally substituted phenyl, a thienyl, a benzothienyl, a naphthyl or an optionally N-substituted indolyl;   - R represents hydrogen or a C1-C6 alkyl; - T represents -CO- or -CW-NH-, W being an oxygen or sulphur atom, and - Z represents either hydrogen, or M or OM when T represents the -CO- group or M when T represents the -CW-NH- group; M represents especially an alkyl, an  alpha -hydroxybenzyl, a  alpha -hydroxyalkylbenzyl, a phenylalkyl, a pyridylalkyl, a naphthylalkyl, a pyridylthioalkyl or a styryl.   APPLICATION: medicaments, in particular for the treatment of pathological phenomena which involve the neurokinin system.
Patent EP-0624257-B1 (EP)
Title: Alignement de composants optiques integres
Inventor: WELBOURN ANTHONY DAVID
IPC: G02B6/42
Filed: 1993-01-20
Granted: 2002-05-02
Abstract: Procédé servant à connecter deux composants (10, 11) tels qu'un laser à semi-conducteurs (11) et une carte-mère (10), de façon que leurs parties fonctionnelles (12, 19) soient alignées de manière prédétermineée. Ce procédé consiste à former le laser par l'intermédiaire d'un traitement qui permet de placer l'orifice de sortie du rayonnement (19) et un élément d'alignement (21) en une position prédéterminée l'un par rapport à l'autre, à former de manière analogue, sur le carte-mère (10), un guide d'ondes (12) et un élément d'alignement (16, 14), à monter le laser (11) sur la carte-mère (10) en une position généralement alignée, à appliquer de la brasure (26) entre les pastilles métalliques (18, 22) sur le laser (11) et la carte-mère (10), et à utiliser la tension de surface du métal fondu (26) s'étendant entre les pastilles (18, 22) pour déplacer le laser (11) vers une position précisément alignée sur la carte-mère (10).
Patent EP-0631508-B1 (EP)
Inventor: SCHOEN RUDOLF
IPC: A61M25/00
Filed: 1993-03-19
Granted: 1997-06-04
Abstract: The suction catheter tube with continuous lumen connects proximal to a connector, etc. and is reinforced outside at the distal end in ring form and has here equi-spaced radial openings round the tube. The distal outlet (21) of lumen (13) is of funnel form in relation to the remaining lumen sections so the funnel shape is expanded by two equi-spaced peripheral notches (22,23) in the radial sense reaching into the lumen. The distal outlet (21) terminates in an axial beading (20).
Patent EP-0603351-B1 (EP)
Inventor: SIEGEL ROLF RAINER
IPC: C08J7/12
Filed: 1993-05-13
Granted: 2001-02-14
Abstract: A procedure is described for wet chemical surface modification of formed articles and substrates coated with made of organopolysiloxanes: the articles formed were contacted with metal hydroxide solutions to tailor the binding capacity for ions, particularly metal ions, bivalent cations, organic macro anions, and organic macro cations, e.g. proteins. The procedure creates organopolysiloxane surfaces which are better wettable, have reduced surface resistance, are less sticky, are smoother and more biocompatible.
Patent EP-0656775-B1 (EP)
Inventor: LUDWIG JENNIE SUE GALLOWAY
IPC: A61K47/18
Filed: 1993-08-13
Granted: 1997-12-29
Abstract: A controlled sustained release tablet having at least one year shelf life and containing bupropion hydrochloride, hydroxypropyl methylcellulose and cysteine hydrochloride or glycine hydrochloride with the tablet having a surface area to volume ratio to effectively control bupropion hydrochloride release in the body.
Patent EP-0704051-B1 (EP)
Inventor: SUGAR THOMAS GERARD
IPC: G01M3/02
Filed: 1993-08-12
Granted: 1997-10-01
Abstract: L'invention concerne un appareil pour tester par centrifugation l'imperméabilité d'un article chaussant. L'appareil centrifugeur peut aussi être utilisé pour tester d'autres accessoires tels que des gants, des chaussettes, des pantalons, des bottes cuissardes et des chapeaux.
Patent EP-0731739-B1 (EP)
Inventor: ROSENE RONALD G
IPC: B21D28/00
Filed: 1993-10-06
Granted: 1999-06-16
Abstract: A punch guide sleeve and stripper plate assembly useable with a punch set of the type having a punch disposed within the guide sleeve (16) and adapted to be reciprocally advanced through an opening of the stripper plate (12) attached to one end of the guide sleeve (16) by the ram of a punch press. The stripper plate assembly includes a rotatable stripper plate cap (20) which may be manually rotated with respect to the guide sleeve (16) from a locked to an unlocked position to secure and release the stripper plate (12) through tightening and loosening a retaining wire (18) onto and away from the stripper plate (12). The retaining wire has two ends (19, 21) that are attached to the stripper plate cap and the guide sleeve. When these two ends are drawn together in the locked position, the arcuate wire (18) engages with the stripper plate (12).
Patent EP-0633276-B1 (EP)
Inventor: VOGEL CHRISTOPH DIPL-ING
IPC: C08G101/00
Filed: 1994-06-24
Granted: 1998-01-28
Abstract: In the production of mouldings and fillings made from rigid and flexible polyurethane foams and rigid polyurethane foams containing isocyanurate structures made from polyol and isocyanate and activator and optionally further additives, flaws in the foam can be avoided by increasing the amount of activator during the preparation of the reaction mixture - considered over time - to give a setting time which commences simultaneously everywhere as far as possible.
Patent EP-0662571-B1 (EP)
Inventor: SCHUETTE DR KLAUS
IPC: F16G1/06
Filed: 1994-12-13
Granted: 1997-04-09
Abstract: A power transmission belt comprises a reinforcing layer(14) embedded in an elastomer with a friction-reducing coating(12) on the gripping faces. The coating(12) comprises a cross-linked polymer matrix containing a fluoropolymer. Also claimed is a belt mfg. process in which a liquid polymer matrix containing the fluoropolymer is applied to the appropriate faces of the belt body, dried and cross-linked to bend to the body surfaces(11).
Patent EP-0663492-B1 (EP)
Inventor: LIND STEFAN DIPL-ING FH
IPC: E04F13/14
Filed: 1994-12-17
Granted: 1998-01-28
Abstract: Between the stone plate and the concrete plate a plastics foil is arranged, locating on the surfaces of the plate. For fixture of the stone plate (1) to the concrete plate (2), in the stone and concrete plates are arranged screw anchors (12) vertically to the dividing surface, which are fixed in the stone plate in a hole (8) with back cut via a head and a bracing part (13) supporting on it. The screw anchors are so held in the concrete plate that a socket (4) cast with the concrete plate, which encloses the shaft (11) of the screw anchor, permits a compensation movement in a radial direction. The socket is formed as a concreted-in bolt which has a longitudinal bore with a thread-free section (20) to which is connected a section with an inner thread (10).
Patent EP-0655766-B1 (EP)
Inventor: JAMAR JACOBUS HUBERTUS THEODOO
IPC: H01J29/70
Filed: 1994-11-21
Granted: 1997-11-05
Abstract: Display tube comprising a deflection unit provided with a (twist) correction device which comprises an annular (twist) correction coil surrounding the tube neck, which coil, when energized by a circuit providing a (twist) correction current, generates a magnetic correction field in the axial direction of the display tube. According to the invention, the device also provides a 4-pole y field for correcting (twist) errors in the centre of the display screen. This 4-pole y field can be generated by causing the turns of the annular coil to follow a path having four predetermined corrugations alternately facing the display screen and the electron gun. <IMAGE>   <IMAGE>
Patent EP-0659494-B1 (EP)
Inventor: BAENSCH MICHAEL
IPC: B21B41/08
Filed: 1994-12-05
Granted: 1998-03-18
Abstract: The invention relates to a device for discharging cold rolled tubes after a cold pilger mill with stepwise feed and/or rotation of the tube, in which the tube is deflected from the rolling direction in a buffer zone between the rolling zone and a driver (pinch roll unit) operating at constant speed to compensate for the cyclically nonuniform rolling speed. According to the invention, the tube (R) is deflected in a S by constrained guidance. <IMAGE>
Patent EP-0630575-B1 (EP)
Inventor: SERPELLONI MICHEL
IPC: A23L33/00
Filed: 1994-05-11
Granted: 1999-12-22
Abstract: The invention relates to a process for coating with maltitol enabling a coating to be created easily and quickly on the surface of the product. This process consists, on the one hand in applying a carbohydrate syrup, a protein syrup or steam, and on the other hand in applying, in pulverulent form, an amount of maltitol-containing powder having a purity of greater than 87%.
Patent EP-0624597-B1 (EP)
Inventor: ROSA CARLO
IPC: C07K14/18
Filed: 1994-05-02
Granted: 1999-02-10
Abstract: Peptides comprising at least one of the dominant epitopes of the NS4b or NS5a HCV proteins and uses thereof for immunodiagnostics are described. <IMAGE>
Patent EP-0680540-B1 (EP)
Inventor: HOLT EDWARD CHRISTOPHER
IPC: E04G21/28
Filed: 1994-01-20
Granted: 1998-09-30
Abstract: A scaffolding system comprising a spaced pair of columns (40), each column being mounted on a transportable base so as to be pivotable between a generally horizontal orientation and a vertical orientation, and connecting means (41) attachable to each of the columns in the pair when vertical, to extend therebetween.
Patent EP-0676973-B1 (EP)
Inventor: LATTIN GARRY A
IPC: A61N1/30
Filed: 1993-12-30
Granted: 1998-01-28
Abstract: A device for the electrically assisted delivery of a therapeutic agent is described. The device (500) comprises one or more rigid zones. The skin side of the rigid zone has a radius of curvature (520) which approximates that of the body site to which the device (500) is to be attached. <IMAGE>
Patent EP-0687237-B1 (EP)
Inventor: HOFFMAN DALYN C
IPC: B65B35/56
Filed: 1994-02-14
Granted: 1998-05-27
Abstract: An article handling device for handling identical articles having one end that is thicker than the other end entering the device along a supply path containing a plurality of identically aligned articles wherein the leading end of each article is of the same thickness. The article handling device effects a dividing of a specified number of articles entering a transfer section into two groups, a first group being transferred directly to an exit section, a second group being transferred directly to a reversing section while a still further third group, previously transferred to the reversing section and reversed in orientation relative to the first and second groups, is transferred from the reversing section to the exit section. The first and third groups of articles are thereafter united as the orientation of the second group is reversed. The united first and third groups form a solid rectangular volume which can be easily packaged with no wasted space.
Patent EP-0649318-B1 (EP)
Inventor: VETTER HELMUT
IPC: A61M5/31
Filed: 1994-05-03
Granted: 1999-03-24
Abstract: The syringe for medicinal purposes consists of a syringe barrel (1), one end of which is formed as an adapter (2) for a cannula or a closure (3), e.g., in the form of a tip cap, and of a plunger (4), arranged within the syringe barrel (1), and movable by a piston rod (5). At the end of the syringe barrel (1) facing away from the adapter (2), a plunger brake (6) is arranged, which is formed by a rest piece surrounding the syringe barrel (1) and connected removably to it. The rest piece has a projection extending into the lumen of the syringe barrel (1), which forms a stop for the side of the plunger (4) away from the adapter (2).
Patent EP-0684899-B1 (EP)
Inventor: SEEMAN WILLIAM
IPC: B29C70/44
Filed: 1994-02-07
Granted: 2002-01-16
Abstract: An unitary vacuum bag for forming of a fiber reinforced composite article, made of a curable elastomer, having molded in resin distribution means formed to the specific article to be made. Optional vacuum conduits are molded into the periphery of the bag, causing the bag to be adapted to any number of mold shapes. The vacuum bag is constructed upon that mold which forms the base for the construction of the desired fiber reinforced composite article. The bag contains an open sided, resilient main distribution conduit running laterally along the long axes of the vacuum bag with branch conduits, depending upon the shape of the mold, to provide for long distance flow of resin to all parts of the composite article. A multiplicity of cross channels are formed on the inner surface of the bag, covering most of the area under which the fiber lay up is placed within the mold. These cross channels can be formed from a pattern of multiple, variegated small dots, pillars, cones, or pyramid shape structures, which, under vacuum, leave a multiplicity of small crisscross channels running along the inner surface of the vacuum bag. This pattern of distribution channels covers most of the fiber lay up, except for a perimeter area which insures resin flow into rather than across the fiber lay up.
Patent EP-0656932-B1 (EP)
Inventor: RADFORD TERENCE
IPC: A61K36/752
Filed: 1994-06-21
Granted: 2001-01-10
Abstract: A process for transforming and removing latent sediment-forming components from citrus oils to supplement a dewaxing process for the citrus oils. Psoralen epoxides in citrus oils are converted to diols in an accelerated and controlled manner. The epoxide-to-diol transformation is effected by mixing citrus oil with an aqueous acidic treatment solution under conditions (i.e., solution pH and volume) and for a sufficient period of time to convert substantially all of the psoralen epoxides. The diols formed thereby are precipitated and/or preferentially dissolved in the aqueous phase during mixing. Upon separation of the aqueous phase from the oil, the citrus oil is substantially free of psoralen epoxides. By this method, epoxides are inexpensively eliminated from the citrus oils, resulting in an improved product having, for example, reduced sedimentation potential and reduced phototoxicity.
Patent EP-0786985-B1 (EP)
Title: Methode et composition pour traiter les etats anormaux de l'epithelium des orifices du corps
Inventor: RATCLIFF PERRY A
IPC: A61K8/24
Filed: 1994-07-05
Granted: 2001-12-05
Abstract: L'invention concerne une solution, une crème, un onguent ou un aérosol stables, contenant du dioxyde de chlore activé et stabilisé ainsi que des phosphates tels que le dihydrogénophosphate de sodium, l'hydrogénophosphate de sodium, le phosphate de sodium trisodique et le monofluorophosphate de sodium. Cette composition est utile pour la prévention et le traitement d'états anormaux de l'épithélium d'orifices du corps. Comme exemples de ces états anormaux de l'épithélium des orifices rectal, vaginal, uréthral, buccal, nasal, oculaires et auditifs, on peut citer les leucoplasies et les infections bactériennes causées par Actinobacillus actinomycetemcomitans et par Porphyromonas gingivalis ainsi que les infections fongiques telles que celles causées par Candida. Les plages de concentrations préférées sont environ de 0,005 % à 2,0 % pour le dioxyde de chlore et environ de 0,02 % à 3,0 % pour le phosphate. Le phosphate retarde la libération du dioxyde de chlore dans la plage des valeurs de pH de 6,0 à 7,4. A ces valeurs du pH, le dioxyde de chlore stabilisé est activé et suffisamment de dioxyde de chlore est libéré pour diminuer la mobilité et tuer les micro-organismes en question.
Patent EP-0716688-B1 (EP)
Title: Culture medium and process for the preparation of high molecular weight hyaluronic acid
Inventor: CAZZOLA FLAVIA
IPC: C12P19/26
Filed: 1994-07-29
Granted: 2003-09-24
Abstract: Provided are an economical culture medium useful in the production of high levels of hyaluronic acid having a molecular weight in the range from 2 to 3.1 x 10<6> Daltons by bacterial fermentation, a process for producing high molecular weight hyaluronic acid by bacterial fermentation employing this medium, and a method for purifying hyaluronic acid produced by bacterial fermentation. Also provided are pharmaceutical compositions containing hyaluronic acid produced by the present process, and a method of treating wounds and surgical incisions to avoid hypertrophic scar and keloid formation.
Patent EP-0671176-B1 (EP)
Inventor: SHIKINAMI YASUO
IPC: A61K9/70
Filed: 1994-09-27
Granted: 2001-06-06
Abstract: A percutaneously absorbable preparation which can long stably preserve a water-soluble drug capable of exhibiting the effect in a small dose and being readily decomposable, solid at ordinary temperature and difficultly absorbable percutaneously and which can sustainedly release the drug percutaneously at a high rate when applied to the skin. The preparation comprises a drug store layer wherein a drug is incorporated and a drug release control membrane for coating the drug release surface of the drug store layer. This layer is made from a heat-sensitive segmented polyurethane which is represented by the following general formula: R-A-(U)-F-(U)-B-R', (wherein A and B represent each a homopolymer or a random or block copolymer of ethylene oxide, propylene oxide, tetramethylene oxide or 1,2-butylene oxide; R and R' represent each H, CH3, C2H5, C3H7 or C4H9 as the terminal of each of A nad B; A=B or A NOTEQUAL B; R=R' or R NOTEQUAL R'; F represents the residue of a diisocyanate compound; and (U) represents a urethane bond) and wherein at least one of A and B is hydrophilic and at least one of them will melt near the human skin temperature. The drug release control membrane comprises a phase-separation membrane wherein a cross-linked gelatin phase and a non-cross-linked segmented polyurethane phase are intermingled.
Patent EP-0696608-B1 (EP)
Inventor: DAUTH JOCHEN DR
IPC: C08G77/48
Filed: 1995-07-27
Granted: 1996-12-11
Abstract: Organosilanes and organopolysiloxanes (I) with radical-forming gps. contain 0.1-100 wt.% units of formula ÄRaSi(O13a/2Ü-R<1>-C6H4-xR5x-N=N-Sy-R1-R2Ü (1) 0-80 wt.% units of formula ÄR<2>3SiO1/2Ü (2) 0-99.9 wt.% units of formula R<2>2SiO2/2Ü (3) 0-80 wt.% units of formula ÄR<2>SiO3/2Ü (4) and 0-80 wt.% units of formula ÄSiO4/2Ü (5) R = Cl, Br, OH, 1-18C alkoxy, or 1-18C hydrocarbyl, opt. substd. with halo, amino, OH, epoxyalkyl or CN; R<1> = direct bond or 1-18C hydrocarbylene, opt. substd. with halo, amino, OH, acyloxy, epoxyalkyl or CN and opt. contg. in -chain -O-, -S-, -COO-, -OOC-, -CONR<2>-., -NR<2>- or -CO- gps.; R<2> = H or R; R<5> = halo, CN, nitro, -R, -OR or -COR; a = 0, 1, 2 or 3, with a = 3 if the amt. of (1) is 100 wt.%; x = 0, 1, 2, 3 or 3; y = 0 or 1.
Patent EP-0703224-B1 (EP)
Inventor: WROBLOWSKY HEINZ-JUERGEN DR
IPC: C07D249/12
Filed: 1995-09-11
Granted: 1997-09-03
Abstract: Prepn. of a 5-hydrocarbyloxy-4-hydrocarbyl-2,4-dihydro- 3H-1,2,4-triazol-3-one of formula (I) comprises: (i) reacting an iminothiocarbonate diester of formula (II) with a carbazate ester of formula (III) (or its acid adduct), opt. in presence of a reaction auxiliary and/or a diluent, at -20 to +50 (pref. -10 to +40, esp. 0-30) degrees C; and (ii) subjecting the obtd. semicarbazide deriv. of formula (IV) (or its tautomer), opt. after isolation, to cyclising condensation at 20-100 (pref. 30-90 esp. 40-80) degrees C, opt. in presence of a base and/or a diluent. R<1>, R<2>= alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl (all opt. substd.); R<3>, R<4> = alkyl, aryl or aralkyl (all opt. substd.).
Patent EP-0720050-B1 (EP)
Inventor: MAURER WILHELM
IPC: G03F1/82
Filed: 1995-12-19
Granted: 1999-06-02
Abstract: An apparatus and associated method for removing microscopic particle contaminants from an object such as a photomask or a semiconductor wafer. The apparatus utilizes an inspection device to identify the position of any particle contaminants on the target object. Once the positions of the various particle contaminants has been identified, a probe is dispatched to the position of one of the particle contaminants. The probe removes the particle contaminant from the target object and moves to a cleaning compartment, wherein the particle contaminant is removed from the probe. The probe is then moved to the next subsequent particle contaminant until all the contaminants are removed from the target object. By removing particle contaminants one-by-one from the target object, the manufacturing yield of zero defect products is greatly increased. <IMAGE>
Patent EP-0690521-B1 (EP)
Inventor: KORALL MENACHEM
IPC: H01M50/423
Filed: 1995-06-09
Granted: 1999-03-03
Abstract: In a mechanically rechargeable electrochemical metal-air battery, each cell comprises: (a) a housing contg. a replaceable metal electrode which has an electrically conductive skeleton covered by an active metal component and which can be replaced by a freshly charged metal electrode through a housing opening opposite the housing base; (b) one or more planar air-permeable liq.-impermeable air electrode, each installed in a window-like opening in one or more major surfaces of the housing; and (c) an electrolyte in contact with the metal and air electrodes. A first woven mesh separator is attached to an inner, electrolyte-facing surface of the or each air electrode and a second woven mesh separator is attached to and covers a major metal electrode surface facing the or each air electrode, the separators being in sliding relationship to each other.
Patent EP-0759806-B1 (EP)
Title: Dispositif pour le melange de deux fluides
Inventor: GADDIS EDWARD SHAFIK
IPC: B01F5/02
Filed: 1995-03-31
Granted: 1998-09-30
Abstract: L'invention a pour objet un dispositif pour le mélange de deux fluides, dont au moins un est un liquide, présentant un récipient tubulaire (1) ouvert à ses deux extrémités axiales, destiné à contenir le fluide, au moins deux buses (3, 4) séparées l'une de l'autre pour l'alimentation en fluide, et un dispositif d'alimentation dans une extrémité duquel les buses (3, 4) font saillie. Le dispositif l'alimentation débouche, par son autre extrémité, à peu près en son milieu, dans le récipient (1) ouvert à cet endroit et définit une zone d'impact (PZ) à cet endroit, dans laquelle les courants de fluide injectés par les buses (3, 4) à leur sortie du dispositif d'alimentation se heurtent mutuellement. Le dispositif d'alimentation fixé solidairement au récipient (1) présente au moins deux parois fermées formant entre elles un espace creux et est ouvert à ses deux extrémités. L'une des parois du dispositif d'alimentation constitue la paroi du récipient (1).
Patent EP-0706493-B1 (EP)
Inventor: HOFMANN ARMIN
IPC: B65G47/51
Filed: 1995-05-02
Granted: 1998-03-25
Abstract: PCT No. PCT/CH95/00098 Sec. 371 Date Feb. 9, 1996 Sec. 102(e) Date Feb. 9, 1996 PCT Filed May 2, 1995 PCT Pub. No. WO95/29863 PCT Pub. Date Nov. 9, 1995A suspended storage apparatus in which products (16) are placed in trays (14) supporting shelves (15) for carrying the products. The receiving station of the apparatus comprises an assembly consisting of a pushing device connected to a first drive mechanism (101A), the pushing device including at least one substantially horizontally movable pushing member (107) for transferring products from the shelves to a conveyor belt (108), and a second drive mechanism (101B) for moving the pushing member substantially vertically as it moves horizontally. This combination of two directions of motion enables continuous discharge of the products.