baber/WOPTO huggingface dataset:
Patent CA-2460392-A1 (CA)
Title: Recombinant allergen with reduced ige binding but undiminished t-cell antigenicity
Inventor: SWOBODA INES
IPC: C12N15/13
Filed: 2002-09-13
Abstract: The present invention relates generally to reagents useful in the immunotherapeutic or immunoprophylactic treatment of allergic diseases. More particularly, the present invention provides modified allergens exhibiting reduced IgE interactivity including reduced IgE production-stimulatory activity, while retaining T-cell antigenicity, which are useful in the immunomodulation of type I allergic disease conditions. The present inventio n further contemplates a method of immunomodulation of allergic diseases such as type I allergic disease conditions by the administration of modified allerge ns exhibiting reduced IgE interactivity while retaining T-cell antigenicity.</S DOAB>
Patent CA-2461319-A1 (CA)
Title: Contact management for mobile communication devices in wireless packet switched networks
Inventor: WANDEL MATTHIAS
IPC: H04L12/56
Filed: 2002-09-27
Abstract: Methods and apparatus for maintaining contact with a wireless communication network improve the timeliness in which traffic is delivered to a mobile communication device in marginal coverage areas. The number of times the mobile device informs the network of its presence in such coverage may be reduced based on predetermined network characteristics. In one illustrative example, the method involves continually maintaining and updating a message decode history list in memory and comparing it with a predetermined paging pattern of the network. The message decode history list keeps track of whether or not each message of a most recent plurality of regularly broadcasted messages has been successfully decoded. An update message which informs the network of the mobile device is transmitted in response to identifying that unsuccessful message decode indicators in the history list overlap with all page transmission periods of the network paging pattern. Conversely, the update message is not normally transmitted in response to identifying that any successful message decode indicator in the history list overlaps with any page transmission period of the network paging pattern.
Patent CA-2462255-A1 (CA)
Inventor: IIDA AKIHIRO
IPC: C12N15/86
Filed: 2002-09-27
Abstract: L'invention concerne un agent anti-inflammatoire non stéroïdal et un myorelaxant permettant de réguler l'expression d'un gène porté sur un vecteur viral. Ces médicaments permettent également de réguler la cytotoxicité du vecteur viral. L'invention concerne un procédé de régulation de l'expression d'un gène porté sur un vecteur viral, faisant appel à l'utilisation d'un agent anti-inflammatoire non stéroïdal et/ou d'un myorelaxant. Ces médicaments permettent d'atteindre des effets réversibles. C'est-à-dire qu'une expression génique élevée à partir du vecteur viral, et qu'une augmentation au niveau de la cytotoxicité du vecteur viral sont observées après l'arrêt de l'administration de ces médicaments. Les médicaments susmentionnés sont utiles au niveau de la régulation de l'expression d'un gène de virus et d'un gène thérapeutique en thérapie génique, par le biais de l'utilisation d'un vecteur viral pour une thérapie génique, et sont utiles pour réguler la cytotoxicité du vecteur viral.
Patent CA-2464116-A1 (CA)
Title: Document exchange using extensible markup language
Inventor: BEHZADI AZAD E
IPC: G06F17/21
Filed: 2002-10-18
Abstract: A system and method for checking and validating Extensible Markup Language (XML) data before sending a XML document to a receiving partner. The XML data tags used by Partner A may be incomprehensible to Partner B. A database is used to reformat the XML document based on the compatibility requirements of the receiving party.
Patent CA-2464172-A1 (CA)
Inventor: MATSUOKA KAZUMI
IPC: C21D7/04
Filed: 2004-04-14
Abstract: A novel treatment method, for improving fatigue life, is provided that aims to resolve problems associated with conventional treatment methods for improving fatigue life of metal by reduction of stress concentration and conventional treatment methods for improving fatigue life of metal by introduction of compressive stress, that is, problems of poor efficiency in work execution, required level of skill of workers, and the impossibility of quality control due to lack of means for measuring the effect after treatment, characterized in that, for locations in metal for which fatigue is a problem, after pre-treatment is performed, ultrasonic impact treatment is performed, and thereafter, a quality assurance test is performed so as to improve the fatigue life of the metal.
Patent CA-2464878-A1 (CA)
Inventor: BERG THOMAS R
IPC: B61F5/30
Filed: 2004-04-20
Abstract: A tuned spring group with load springs, control springs, and a frictional damping arrangement for a railcar truck assembly provides better ride quality, increased resistance to suspension bottoming, and increased hunting threshold speed of a railroad car. Specifically, this tuned damping and suspension arrangement provides a spring group reserve capacity of less than 1.50. Spring assemblies for different car types are tuned such that a reserve ratio less than 1.50 may be achieved. By reducing the spring assembly reserve capacity for a railcar and truck of a standard weight and configuration to less than 1.50, an unexpected result of a decrease in maximum vertical acceleration as the railcar truck assembly approaches a speed of 55 miles per hour is achieved. The decrease in vertical acceleration allows for improved ride quality, increased resistance to suspension bottoming and increased hunting threshold speed of the railcar.
Patent CA-2466779-A1 (CA)
Inventor: WEBER BEAT THEODOR
IPC: C07C211/00
Filed: 2002-12-03
Abstract: L'invention concerne un procédé efficace permettant de préparer de l'O-desméthyle venlafaxine par déméthylation de venlafaxine avec un anion thiolate.
Patent CA-2468501-A1 (CA)
Inventor: CARR FRANCIS J
IPC: C12N15/57
Filed: 2002-11-27
Abstract: The invention in particular relates to the modification of a bacterial enzym e carboxypeptidease G2 (CPG2) to result in CPG2 proteins that are substantiall y non-immunogenic or less immunogenic than any non-modified counterpart when used in vivo. The present invention relates also to T-cell epitope peptides derived from said non-modified protein by means of which it is possible to create modified CPG2 variants with reduced immunogenicity. These polypeptide s are suitable particularly for therapeutic use in humans.
Patent CA-2468824-A1 (CA)
Inventor: SHIMMA NOBUO
IPC: C07D491/22
Filed: 2002-11-25
Abstract: Composé hexacyclique de formule [1] dans laquelle Z, R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans le descriptif et les revendications et sels acceptables sur le plan pharmaceutique dudit composé. Ces composés sont utiles pour traiter les troubles liés à la prolifération cellulaire.
Patent CA-2471382-A1 (CA)
Title: Spinal disc implant
Inventor: DAVIS REGINALD J
IPC: A61F2/30
Filed: 2002-12-27
Abstract: A pseudo arthrosis device (20) may be placed in a disc space to provide support for adjacent vertebrae. The device may have an enclosure (22) formed from a flexible, permeable material. A plurality of elongated members (24) may be packed longitudinally in the enclosure (22). The elongated members (24) may be compressible and/or flexible. In certain embodiments, elongated members (24) may be solid rods and/or hollow tubes. A plurality of spaced-apart perforations may be formed in solid and hollow elongated members. The enclosure may be placed in an intervertebral space between the adjacent vertebrae such that the elongated members (24) are disposed longitudinally between the adjacent vertebrae. The pseudo arthrosis device (20) may include a tab (28) designed to couple the enclosure to an adjacent vertebrae.
Patent CA-2472593-A1 (CA)
Inventor: BENEDICT SHANE R
IPC: A23G3/34
Filed: 2003-01-15
Abstract: The present invention is directed to a process for making confectionery pieces, comprising the steps of (1) providing a solid or semi-solid edible slab having at least three layers to at least two forming elements (50, 55) having a nip (53) defined by the forming elements (50, 55); and (b) passing the edible slab through the nip, thereby forming a sheet of confectionery pieces (60) or individual pieces, wherin the edible lab has a first outer layer (20), a second outer layer (25), and at least one inner layer (26) between the first and second outer layers.
Patent CA-2473572-A1 (CA)
Title: Quinazoline compounds
Inventor: HENNEQUIN LAURENT FRANCOIS AND
IPC: C07D519/00
Filed: 2003-01-28
Abstract: The invention relates to compounds of the formula (I): wherein ring C is as defined herein, for example indolyl, indazolyl or azaindolyl; Z is -O-, -NH- or -S-; n is 0-5; m is 0-3; R1 and R2 are defined herein including groups: (i) Q1X1 wherein Q1 and X1 are as defined herein; (ii) Q15W3 wherein Q15 and W3 are as defined herein, (iii) Q21W4C1-5alkylX1- wherein Q21, W4 and X1 are as defined herein, (iv) Q28C1-5alkylX1-, Q28C2-5alkenylX1- or Q28C2-5alkynylX1- wherein Q28 and X1 are as defined herein and (v) Q29C1-5alkylX1-, Q29C2- 5alkenylX1- or Q29C2-5alkynylX1- wherein Q29 and X1 are as defined herein; R2 can also be 6,7-methylenedioxy or 6,7-ethylenedioxy;and salts thereof; their use in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warmblooded animals; processes for the preparation of such compounds; intermediates used in such processes; processes for making such intermediates; pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof and methods of treating disease states involving angiogenesis by administering a compound of formula I or a pharmaceutically acceptable salt thereof. The compounds of formula I inhibit the effects of VEGF, a property of value inthe treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent CA-2475303-A1 (CA)
Inventor: HAYES PATRICK H
IPC: H04B10/10
Filed: 2002-10-18
Abstract: L'invention concerne un système et un procédé permettant de configurer un appareil de commande de cible afin de communiquer avec un appareil cible commandé. Des informations de configuration sont fournies à une commande à distance afin de configurer ladite commande pour communiquer des codes de commande à l'appareil cible commandé. Une représentation de données de configuration est transmise dans un message configuré à l'appareil de commande de cible. Cet appareil utilise la représentation de données de configuration pour se configurer automatiquement afin de communiquer des codes de commande à l'appareil cible commandé. Cet appareil utilise, notamment, la représentation de données de configuration pour sélectionner ces codes de commande dans une bibliothèque de codes de commande reconnaissables par l'appareil cible commandé. La bibliothèque de codes de commande peut être locale ou distante de l'appareil de commande de cible.
Patent CA-2477502-A1 (CA)
Inventor: KUKLA PETER
IPC: F01N13/04
Filed: 2003-03-03
Abstract: There is disclosed a gas flow arrangement apparatus comprising a gas entranc e (18) and a gas exit (20), a first flow path from the gas entrance to the gas exit through a means (24) for at least partly removing at least one pollutan t from a gas flow stream and second flow path from the gas entrance to the gas exit other than through the removing means (24).
Patent CA-2477899-A1 (CA)
Inventor: NESIC ZORAN
IPC: H02K11/04
Filed: 2004-08-18
Abstract: An integrated, unitary actuator formed of a frame having structure for connecting an actuator motor, a structure for supporting a power translation member, and a structure for enclosing a control circuit. Optionally, a clearance structure of the frame receives a shaft of the actuator motor, and a passage from the control circuit enclosure to the clearance structure provides access for electrical power and sensor information between the control circuit to the actuator motor.      Further optional, a cover plate over the structure for enclosing the control circuit secures the control circuit and provides a single receptacle connection to the vehicle.
Patent CA-2477997-A1 (CA)
Title: Wrapping machine
Inventor: SUOLAHTI YRJO
IPC: B65B11/00
Filed: 2004-08-18
Abstract: A wrapping machine having a pre--stretching device (6) for pre-stretching a film web (1) drawn from film roll before its being wrapped around an object, said pre-stretching device (6) comprising a first pre-stretching roller (7) and a sec-ond pre-stretching roller (9), which are tractively coupled via power transmission gears (11, 12) . A first deflecting pinch roller (13) has been fitted to be pressed against the first pre-stretching roller (7) to form a first nip (14) for the film web passed between the first deflecting pinch roller (13) and the first pre--stretching roller (7). A second deflecting pinch roller (15) has been fitted to be pressed against the second pre-stretching roller (9) to form a second nip (16) for the film web passed between the second de-flecting pinch roller (15) and the second pre-stretching roller (9). A lever mecha-nism (17) moves the first pre-stretching roller (7) between an engagement position (I) and a disengagement position (II), so that the lever mechanism (17) also moves the first deflecting pinch roller (13) apart from the first pre-stretching roller (7) and simultaneously the second deflect-ing pinch roller (15) apart from the second pre-stretching roller (9) to allow easier thread-in of the film web end.
Patent CA-2478012-A1 (CA)
Title: Internalizing anti-cd74 antibodies and methods of use
Inventor: GOLDENBERG DAVID M
IPC: C07K16/28
Filed: 2003-03-03
Abstract: The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
Patent CA-2480934-A1 (CA)
Title: Real time answerprint timing system and method
Inventor: RATTRAY HAROLD L
IPC: G03B21/20
Filed: 2003-04-01
Abstract: A method and system for color correcting and completing answerprints in preparation for making final copies of motion pictures for distribution. A  light system is provided in which colors of the light projected through a film (22) toward a viewing screen (24) can be individually and incrementally adjusted as desired for use by a color "Timer" who is an individual that selects color corrections on a scene-by-scene basis until a suitable look is achieved. Color correction is performed in real time while watching the film scene projected on the screen. The color adjustments are stored and subsequently used to control a motion picture film printer when printing a corrected version of scenes of the film.
Patent CA-2481299-A1 (CA)
Title: Fragmentation of ions by resonant excitation in a low pressure ion trap
Inventor: LONDRY FRANK
IPC: H01J49/42
Filed: 2003-04-02
Abstract: In the field of mass spectrometry, a method and apparatus for fragmenting ions with a relatively high degree of resolution. The technique includes trapping the ions in an ion trap, preferably a linear ion trap, in which the background or neutral gas pressure is preferably on the order of 10-5 Torr. The trapped ions are resonantly excited for a relatively extended period of time, e.g., exceeding 50 ms, at relatively low excitation levels, e.g., less than 1V(0-pk). The technique allows selective dissociation of ions with a discrimination of at least about 1 m/z at a practical fragmentation efficiencies. Apparatus and related methods are also disclosed for obtaining MS, MS2, MS3 and MSn spectrums at relatively high resolutions using the low pressure fragmentation technique.
Patent CA-2482157-A1 (CA)
Inventor: ROZIM PETER
IPC: A24D3/16
Filed: 2002-05-15
Abstract: The filter unit according the invention contains wood cuttings of a particle size of 0.2-1.2 mm impregnated with sodium chloride solution, preferably wit h a solution of 20-40% sodium chloride and 80-60% of water. The wood cutting m ay be in a loose form or the wood cutting particles (9) may be arranged on a ri b (8) made of cellulose-acetate. The filter cigarette containing a filter unit according to invention may contain the filter unit (5) between the filter-ti p (4) and the tobacco body (1) or between two parts of the filter-tip (4). Preferably, the filter unit (5) is separated from the filter-tip (4) and/or from the tobacco body (1) by a web (6). (Fig. 1)
Patent CA-2482281-A1 (CA)
Title: Providing a graphical user interface in a system with a high-assurance execution environment
Inventor: ROBERTS PAUL C
IPC: G06F3/048
Filed: 2004-09-21
Abstract: Techniques are disclosed to provide security for graphical user interface elements being displayed in a system in which a first, host operating system is used along with a second, high assurance operating system, where the first system provides at least some of the infrastructure for the second system. Graphical user interface elements associated with the high-assurance operating system are prevented from being obscured and from any partial transparency. Additionally, a piece of secret information is stored which can be displayed upon command by graphical user interface elements associated with the high-assurance operating system. Coordinating certain elements of the display of all graphical user interface elements associated with the high assurance operating system also helps to identify legitimate elements associated with the high assurance operating system, as opposed to impostor elements which are not. Where a windowing system is used, public title information is furnished to a host operating system windowing system to identify a window owned by a process running on a high-assurance operating system. Private title information associated with the same window is used only in the high assurance operating system.
Patent CA-2482778-A1 (CA)
Title: Wireless shopping system and method
Inventor: DIVEKAR SANDEEP
IPC: G06Q20/00
Filed: 2002-04-19
Abstract: System and method that enables a user to shop for one or more items by comparing the items with similar items using a portable wireless communication device.
Patent CA-2485315-A1 (CA)
Title: Fire protective coat with enhanced sleeve movements and reduced rise
Inventor: TOWLE MIKE
IPC: A41D1/00
Filed: 2004-10-19
Abstract: The outer shell of a fire protective coat includes right and left vertical pleats in its back portion to accommodate forward movement of its sleeves, and its sleeves each include front and rear pleats near where the sleeves connect to the body portion of the outer shell to accommodate upward movement of the sleeves and reduce rising or lifting of the lower edge of the coat. The removable liner therein includes an outer moisture barrier layer and an inner thermal layer, the inner thermal layer including right and left darts in its back portion near where its sleeve portions connect to its body portion and pleats in its sleeve portions near where they connect to its body portion. The moisture barrier layer includes right and left darts in its back portion near where its sleeve portions connect to its body portion and darts in its sleeve portions near where they connect to its body portion. The darts and pleats in the inner and outer layers cooperate with the pleats in the outer shell to provide great flexibility in sleeve movement for the coat and reduced rise.
Patent CA-2485348-A1 (CA)
Title: Dna vaccines against hantavirus infections
Inventor: HOOPER JAY W
IPC: C07K14/175
Filed: 2003-03-21
Abstract: In this application is described a protective DNA vaccines against infection with HFRS- and HPS-associated hantaviruses. The vaccines were constructed by subcloning cDNA representing the medium (M) (encoding the G1 and G2 glycoproteins) into the DNA expression vector pWRG7077. Animals vaccinated with the M construct developed a neutralizing antibody response. Passive transfer experiments show that serum from vaccinated animals, when injected on days 4 or 5 after challenge, protected animals from lethal disease.
Patent CA-2486116-A1 (CA)
Inventor: WINNER BLAIR L
IPC: A23L5/40
Filed: 2003-05-30
Abstract: L'invention concerne un souci, une partie regénérable de celui-ci et une semence dont les pétales des fleurs, les feuilles ou les pétales des fleurs et les feuilles présentent une ou plusieurs teneurs améliorées en néoxanthine et violaxanthine, une teneur améliorée en ?-carotène, une teneur améliorée en lycopène, une teneur améliorée en ?-cryptoxanthine, une teneur améliorée en phytoène ou une teneur améliorée en phytofluène comparativement à une telle teneur chez un souci non mutant. L'invention concerne également un souci, une partie regénérable de celui-ci et une semence dont les pétales des fleurs renferment des esters de zéaxanthine et sont sensiblement exempts d'esters de néoxanthine et de violaxanthine, la zéaxanthine constituant au moins environ la moitié des caroténoïdes pouvant être extraits quand des xanthophylles sont analysés comme étant des alcools. L'invention concerne enfin des procédés de préparation de telles plantes, d'oléorésines et de substances comestibles présentant de telles teneurs en caroténoïdes.
Patent CA-2487363-A1 (CA)
Inventor: UVIEGHARA GREGORY A
IPC: H03K3/356
Filed: 2003-05-23
Abstract: An integrated circuit including a Multi-Threshold CMOS (MTCMOS) latch combining low voltage threshold CMOS circuits with high voltage threshold CMOS  circuits. The low voltage threshold circuits including a majority of the circuits in the signal path of the latch to ensure high performance of the latch. The latch further including high voltage circuits to eliminate leakage paths from the low voltage threshold circuits when the latch is in a sleep mode. A single-phase latch and a two-phase latch are provided. Each of the latches is implemented with master and slave registers. Data is held in either the master register or the slave register depending on the phase or phases of the clock signals. A multiplexer may alternatively be implemented prior to the master latch for controlling an input signal path during sleep and active modes of the latch and for providing a second input signal path for test.
Patent CA-2492837-A1 (CA)
Title: Novel derivatives of cycloalcanodiones, method for the production thereof and their pharmacological applications
Inventor: FUENTES CUBERO JOSE ANGEL
IPC: C07D417/12
Filed: 2003-07-29
Abstract: The invention relates to novel cycloalcanodione derivatives which are agonists of serotonin receptor subtype (5- hydroxytryptamine, 5-HT) 5-HT1A and which are hence useful in the treatment of pathological states for which an agonist of said receptors is indicated. Said derivatives are particularly useful as neuroprotective agents, more particularly in the treatment and prophylaxis of cerebral damage caused by ischemic or traumatic stroke. Said cycloalcanodione derivatives generally correspond to formula (I).
Patent CA-2493573-A1 (CA)
Title: Dental model pouring jig
Inventor: HUFFMAN RONALD E
IPC: A61C13/34
Filed: 2003-08-05
Abstract: The dental model pouring jig of the present invention includes a base member that supports a model base support member and a mold support member. The mod el base support member is secured to the base member and is capable of mounting a dental model base. The mold support member is adjustably secured to the base member and includes a mold platform that is capable of mounting a mold of a person's teeth. At least a portion of the mold platform is configured to be easily detached and reattached to the mold support member. The mold support member is adjustable relative to the model base support member to properly position the mold adjacent the dental model base.