baber/WOPTO huggingface dataset:
Patent CA-2173993-A1 (CA)
Inventor: HALEY BOYD E
IPC: G01N33/60
Filed: 1994-10-19
Abstract: Procédé amélioré permettant de diagnostiquer une maladie, et consistant à détecter une macro-molécule marqueur biochimique spécifique d'une maladie dans un échantillon de sérum ou de liquide céphalo-rachidien extrait. En particulier, une sonde à photo-affinité à marquage radioactif est utilisée pour diagnostiquer une maladie. La maladie d'Alzheimer peut ainsi être diagnostiquée par la détection d'une protéine spécifique de cette maladie, et d'un poids moléculaire d'environ 42 000 daltons, en d'autres termes, la glutamine-synthétase. L'invention se rapporte également à un procédé de détection d'autres états pathologiques tels que le cancer, consistant à détecter la présence ou l'absence de protéines de liaison de nucléotides spécifiques.
Patent CA-2174235-A1 (CA)
Title: Benzo-fused macrocycles promote release of growth hormone
Inventor: DEVITA ROBERT J
IPC: A61K31/395
Filed: 1994-10-28
Abstract: There are disclosed certain novel compounds identified as benzo-fused macrocycles which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused macrocycles as the active ingredient thereof are also disclosed.
Patent CA-2176018-A1 (CA)
Inventor: PONTICELLO GERALD S
IPC: A61K31/34
Filed: 1994-11-21
Abstract: Cette invention concerne de nouveaux composés représentés par les formules structurelles (I) et (II) et qui sont utilisés dans le traitement de l'arythmie cardiaque.
Patent CA-2176594-A1 (CA)
Title: Wide band optical fiber, optical fiber core wire and optical fiber cord
Inventor: FUKUDA SEIJI
IPC: G02B6/028
Filed: 1995-09-13
Abstract: This invention discloses broad bandwidth optical fibers which have a broad bandwidth suitable for data-communication, are free from fiber cracking or chipping if a crimp-type connector is attached with sufficient pulling resistant force to hold the fiber firmly, minimize the connection loss through a small crimping optical loss and a accurate axial alignment, facilitate connection with existing GI quartz optical fibers, which have a fiber diameter of 125 µm, and offer excellent compatibility with such existing GI quartz optical fibers.     Broad bandwidth optical fibers pertaining to this invention are graded index broad bandwidth optical fibers fabricated from a core made of quart-based glass with a graded refractive index profile, a quartz glass cladding provided over said core, and polymer covering layer provided over said cladding, with said polymer covering layer made of a UV-cured hard polymer with a Shore hardness of D 55 or more and a thickness of 5 µm or more. Jacketed optical fiber units are then produced by providing a primary coating over an optical fiber and a secondary coating over a primary-coated optical fiber or fibers. Finally optical fiber cords are produced by providing a polymer sheath around a jacketed optical fiber unit.
Patent CA-2177136-A1 (CA)
Title: Pretargeting methods and compounds
Inventor: YAU ERIC K
IPC: C07K7/52
Filed: 1994-11-22
Abstract: Methods of producing nitro-benzyl-DOTA via tosylate cyclization, direct peptide cyclization of cyclic tetrapeptide, and N-alkylation of a compound having a trifluoroacetamide group with an iodoacetyl derivative are described.
Patent CA-2177826-A1 (CA)
Inventor: PETROFF JORDAN
IPC: A41D25/02
Filed: 1994-11-28
Abstract: The Knotless Necktie (1) is a three component, easy to assemble and adjust, necktie that gives the appearance of being a fashionable knotted necktie but which does not use a knot and eliminates any knot tying. This necktie is comprised of a display streamer (2), a knotshaper (3) and a neck band (7). Each of these components can be made of the same or different materials, design patterns or colors. These components are easily assembled into a complete, ready to wear necktie. From the components of three knotless neckties, each of a different material, design, pattern and color, nine different and fashionable knotless neckties can be assembled. Once the knotless necktie is assembled and adjusted for the wearer's neck size, no further adjustment is needed. This necktie can then be easily taken-off or put-on while maintaining the appearance of a fashionably knotted conventional necktie.
Patent CA-2180347-A1 (CA)
Title: Anti-hepatitis b poly- and oligonucleotides
Inventor: CARMICHAEL ELLEN
IPC: A61K47/48
Filed: 1995-01-11
Abstract: Poly- and oligonucleotides which inhibit virai replication, particularly hepatitis virus replication, such as hepatitis B virus (HBV) replication, are disclosed. Preferred antiviral oligonucleotides include the following: an antiviral poly- or oligonucleotide which hybridizes to at least a portion of an RNA primer-binding region of a viral nucleic acid, preferably a DRII region of HBV DNA; an antiviral polyor oligonucleotide which hybridizes to at least a portion of an RNA primer which binds a viral nucleic acid, preferably a DRII region of HBV DNA, an antiviral poly- or oligonucleotide which hybridizes to a hepatitis virus mRNA encoding a DNA polymerase, preferably an HBV mRNA; an antiviral poly- or oligonucleotide which hybridizes to a hepatitis virus mRNA encoding an envelope protein essential for viral attachment to a target cell, preferably an HBV mRNA encoding a pre-S1 protein; and an antiviral poly- or oligonucleotide which hybridizes to an encapsidation signal of a viral nucleic acid, preferably an HBV cis-encapsidation signal, thereby inhibiting encapsidation of the viral nucleic acid. The disclosed poly- or oligonucleotides can be used for detection of the presence of viral nucleic acid, particularly HBV DNA, in a cell and can be used to treat viral infection in a subject.
Patent CA-2181329-A1 (CA)
Title: Method for purifying polyalkylsiloxanes and the resulting products
Inventor: HENDERSON DANNY LEE
IPC: C07F7/21
Filed: 1996-07-16
Abstract: The present invention is directed to a purified polyalkylsiloxane composition having a boiling point, under atmospheric conditions, of less than about 250°C and containing high boiling impurities, including siloxanes and silanol-terminated siloxanes, that have boiling points, under atmospheric conditions, of greater than about 250°C in a total concentration of less than 14 ppm.  The present invention is further directed to a method of producing a purified polyalkylsiloxane composition, having a boiling point, under atmospheric conditions, of less than about 250°C, by distilling a polyalkylsiloxane starting material containing high boiling impurities having boiling points, under atmospheric conditions, of greater than about 250°C in a total concentration of at least 14 ppm, under conditions effective to produce a purified polyalkylsiloxane composition having a boiling point under atmospheric conditions of less than about 250°C, and containing high boiling impurities, having boiling points, under atmospheric conditions, of greater than about 250°C, in a total concentration of less than 14 ppm.  In preferred embodiments, low boiling components (including silanols and preferably also hexamethylcyclotrisiloxane) are reduced to less than about 100 ppm. The present invention is further directed to a method of producing fused silica glass by conversion of the purified polyalkylsiloxane composition.
Patent CA-2181604-A1 (CA)
Title: Closure and sealing element
Inventor: SHACHI KENJI
IPC: C09K3/10
Filed: 1996-07-16
Abstract: A closure or sealing element for containers, comprising a resin composition principally composed of a polyolefin resin (A) and a block copolymer (B) of a polymer block of an aromatic vinyl compound and an isobutylenic polymer block at a (A)/(B) weigh ratio within a range of 100/5 to 100/100, has so suitable pliability and excellent thermal resistance, good gas barrier properties and great oil resistance, that the closure or sealing element has good mountability onto (into) containers and excellent sealing properties of the containers in addition to good long-term shelf stability of the contents.
Patent CA-2184899-A1 (CA)
Inventor: ZEFFERINO RIGHETTTO
IPC: C08B37/08
Filed: 1995-03-13
Abstract: L'invention se rapporte à des esters actifs de carboxy polysaccharides et à des dérivés semi-synthétiques de carboxy polysaccharides dans lesquels tout ou partie des groupes carboxy de ceux-ci sont estérifiés avec un alcool aromatique, un alcool aromatique substitué, un alcool hétérocyclique aromatique, un alcool hétérocyclique aromatique substitué, une N-hydroxylamine, ou une combinaison de ceux-ci. L'invention se rapporte également à un procédé de production de ces esters actifs. Ces esters actifs peuvent être utilisés dans la préparation de carboxy polysaccharides modifiés ou de dérivés semi-synthétiques modifiés de ces carboxy polysaccharides, sous la forme d'esters, de thioesters, ou d'amides. Ces esters actifs, ces polysaccharides modifiés et ces dérivés semi-synthétiques modifiés de carboxy polysaccharides peuvent être utilisés dans les domaines biomédicaux et pharmaceutiques pour préparer, par exemple, des articles cosmétiques, des articles de soin, des articles chirurgicaux et des kits de diagnostic.
Patent CA-2186359-A1 (CA)
Title: Superconductive junction
Inventor: CHEW NIGEL GORDON
IPC: H01L39/24
Filed: 1995-03-10
Abstract: A superconductive junction (10) comprises a first track (22) of YBa2Cu3O7 surmounted by a second track (28) also of YBa2Cu3O7. An interconnect (26) in the form of a superconductive mesa electrically connects the first track to the second track and acts as a microbridge. When cooled below a critical temperature, the junction (10) shows Josephson-like behaviour. A non-superconductive layer (24) of PrBa2Cu3O7 separates the first track and the second track, with the interconnect extending through the PrBa2Cu3O7 layer in the form of an island. The junction (10) is fabricated by electron beam evaporation, optical lithography, and ion beam milling.
Patent CA-2186394-A1 (CA)
Title: Data structure and method for publishing electronic and printed product catalogs
Inventor: POVILUS DAVID S
IPC: G06Q30/06
Filed: 1996-09-24
Abstract: The specification discloses a data structure and method for creating, maintaining, and publishing multiple renditions of both electronic and printed, single and multi-manufacturer catalogs using a single product database. Also disclosed is an electronic catalog created using the data structure and methodology of the present invention. The data structure includes means for creating a product database and means for creating a KnowledgeBase, which includes a concept structure for at least one product realm and a glossary. The concept structure includes at least one concept frame for defining classes of product groupings, where the concept frames include a plurality of concept nodes having relationships based upon characteristics of the products within the product realm. The product database preferably includes a listing of SKUs, each SKU corresponding to a product or a component of a product. The product database further including product information for each associated SKU, and an identification of each concept node in which each SKU can be located. The glossary is used for searching for a particular product or group of products having desired characteristics, and includes a plurality of phrases, at least one of which being a definer that links the phrase to one of the concept nodes.
Patent CA-2188407-A1 (CA)
Title: Active perfusion dilatation catheter
Inventor: SOLAR RONALD J
IPC: A61F2/958
Filed: 1995-04-19
Abstract: The invention relates to an active perfusion dilation catheter (1).  More particularly, the invention relates to an active perfusion dilation catheter (1) comprising a catheter shaft (2) having proximal and distal portions and one or more inflation lumens (5) extending therethrough; an inflatable dilatation balloon (3) positioned external to the distal portion of the catheter shaft (2) and in fluid communication with an inflation lumen (5); an occlusion balloon (4) positioned external to the distal portion of the catheter shaft (2) and proximal to the dilatation balloon (3) in fluid communication with an inflation lumen (5); and a perfusion lumen (6) at the distal portion of the catheter shaft (2), the perfusion lumen (6) having proximal (7) and distal (8) openings, the proximal opening (7) being located proximal to the occlusion balloon (4) and the distal opening (8) being located distal to the inflation balloon (3).
Patent CA-2192798-A1 (CA)
Inventor: SATO MASAKAZU
IPC: C07D277/44
Filed: 1995-06-12
Abstract: Dérivé de thiazoline, ou sel dudit dérivé, destiné à fournir un composé utile contre l'agrégation plaquettaire, pour administration intraveineuse, de formule générale (I) dans laquelle R?1¿ représente hydroxy, alcoxy, cycloalcoxy ou R?4¿NH- (R?4¿ représentant cycloalkyle); R?2¿ représente alkyle ou cycloalkyle; R?3¿ représente hydrogène ou alkyle et n représente un nombre entier de 2 à 9.
Patent CA-2196117-A1 (CA)
Inventor: GILLIE TRENT B
IPC: E03C1/30
Filed: 1997-01-28
Abstract: A drain apparatus includes a conduit and a fitting sealingly connected to the conduit having a pivotable member mounted thereon. There is a rod-like member extending slidably through the pivotal  member into the conduit. The rod-like member can be moved axially and pivotally inside the conduit to clear obstruction therein. For example, the first conduit and the second conduit may be adjacent portions of an elbow. The pivotable  member may be a ball-like member received in a socket in the fitting.
Patent CA-2196344-A1 (CA)
Inventor: SCHMIDT WILLIAM P
IPC: G02B5/00
Filed: 1997-01-30
Abstract: The present invention provides a combination curved and flat mirror lens having a comparatively flatter top portion and a substantially convex or curved lower portion integrally formed to the top portion.  The lens has a maximum radius of curvature at one end thereof continuously varying to a minimum radius of curvature at an opposite end.  The present invention additionally provides means for forming such a mirror lens.
Patent CA-2198182-A1 (CA)
Title: Rotary Control Valve for a Water Conditioning System
Inventor: ALTSHULER EDWARD L
IPC: F16K11/085
Filed: 1997-02-21
Abstract: A rotary control valve is provided for a liquid conditioning system. The rotary control valve includes a housing having a chamber formed about a central axis. The housing includes a plurality of ports aligned with one another along an axis generally parallel to the central axis. A rotor is located within the chamber and is selectively rotatable about the central axis. The rotor includes a central tubular wall extending along the central axis which includes a central fluid flow path. The rotor includes an inlet port adapted to provide fluid communication between the central fluid flow path and a source of untreated liquid. The rotor also includes a plurality of longitudinal sectors wherein each sector includes one or more radial chambers located in one or more tiers of the sector. One or more of the radial chambers in each sector includes an aperture to provide fluid communication between the central fluid flow path and the radial chamber. The radial chambers include respective peripheral apertures adapted to selectively place the radial chambers of a sector in fluid communication with one or more of the ports of the housing when the sector is rotated into alignment with the ports in the housing. Selective rotation of the rotor about the central axis to a selected rotational position opens and closes various fluid paths through the rotor and the housing.
Patent CA-2200343-A1 (CA)
Title: Vehicle powder coating system
Inventor: LADER HARRY J
IPC: B05B14/43
Filed: 1995-08-29
Abstract: An apparatus for applying powder coating material onto large objects such as automotive, truck or other vehicle bodies (32) includes a powder spray booth (12) defining a controlled area within which to apply powder coating material onto the vehicle bodies (32), a powder kitchen (14) located at a remote position from the powder spray booth (12) and, a number of feed hoppers (68, 96) located proximate the booth (12) which receive powder coating material from the powder kitchen (14) and supply it to automatically or manually manipulated powder spray guns (42, 46) associated with the booth. Oversprayed powder coating material is removed from the booth interior (12) by a powder collection and recovery system (16) which transmits the oversprayed powder back to the powder kitchen (14) for recirculation to the powder spray guns (42, 46).
Patent CA-2200682-A1 (CA)
Inventor: FULLER ROBERT M
IPC: H04M3/56
Filed: 1995-09-21
Abstract: L'invention concerne un procédé et un appareil pour mettre un demandeur en communication téléphonique avec un abonné. Un appel du demandeur dirigé vers l'abonné est détecté (10) et en réponse à cela, l'abonné est recherché et en même temps un appel est effectué sur un tronçon en aval, vers une adresse téléphonique mémorisée. Si une réponse est donnée à cet appel sur le tronçon aval, le correspondant qui répond à celui-ci est mis en télécommunication avec le demandeur. Un appel de l'abonné est également détecté et l'abonné est mis en télécommunication avec le demandeur, en même temps qu'un autre correspondant quelconque sur un appel du tronçon aval.
Patent CA-2200746-A1 (CA)
Title: Injection-molded dosage form
Inventor: DONG LIANG C
IPC: A61K47/34
Filed: 1995-10-20
Abstract: The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for expanding for pushing the therapeutic composition from the dosage form in the compartment; (d) exit means in the dosage form that connects the therapeutic composition with the environment of use, and wherein the dosage form is characterized by: (e) an injection-molded membrane with a softening point below 200°C, permeable to the passage of fluid that surrounds and defines the internal compartment, the injection-molded membrane comprising (i) polycaprolactone or a polycaprolactone copolymer; and (ii) one or more members selected from poly(alkylene oxide) and poly(ethylene glycol).
Patent CA-2201122-A1 (CA)
Title: Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone
Inventor: DEGHENGHI ROMANO
IPC: A61K38/08
Filed: 1995-09-13
Abstract: A peptide of the formula: A-D-Mrp-(Ala)n-B-C wherein A is any natural L-amino acid or its D-isomer with the proviso that A is not His if B is Trp and C is DPhe-Lys-NH2; or A is imidazoleacetyl, isonipecotyl, 4-aminobutyryl, 4 (aminomethyl)cyclohexanecarbonyl, Glu-Tyr-Ala-His, Tyr-Ala-His, Tyr-His, D-Thr-His; D relates to the dextro isomer, Mrp is 2-alkyltryptophan; n is 0 or 1; B is L- or D-Trp, Phe or D-.beta.-naphthylalanine, C is NH2, D-Phe-LysNH2, D-Trp-LysNH2, D-Phe-Lys-NH2, Phe-Lys-NH2, D-Phe-Lys-ThrNH2, D-Phe-Lys-D-ThrNH2, OR, wherein R is a C1-C3 alkyl group, and the addition salts with pharmaceutically acceptable organic or inorganic acids of anyone of said polypeptides, these compounds are capable of promoting the release of growth hormone, and are active by the oral route.
Patent CA-2201661-A1 (CA)
Inventor: WEIGHTMAN BRUCE
IPC: E21B34/04
Filed: 1997-04-03
Abstract: A valve actuator is disclosed that can be selectively driven by hydraulic or electrical power, or both, in the alternative. A driving motor engages a drive which, through a clutching mechanism ultimately engages the actuator shaft. The actuator shaft has a spiral groove which is ultimately engaged by cammed spheresmoved into the groove, thus making the drive system which is retained longitudinally, drive the shaft upon rotation of the drive system. Upon release of energy to the driver, be it electrical, hydraulic, or pneumatic, the clutching system disengages so that the balls come out of contact from the spiral groove allowing a return spring to snap the valve shut by longitudinal movement of the actuator shaft.
Patent CA-2202101-A1 (CA)
Inventor: WOODS JOHN R
IPC: E04F21/08
Filed: 1997-04-08
Abstract: A tool for use in connection with a wall covering material source having a nozzle to dispense wall material to be applied to a wall. The tool comprises a plate having a front surface, and a back surface which is adapted to slide along the wall surface. The back surface defines an opening, and the plate defines a passageway passing through the plate and coupled to the back surface opening. A tube connected to the front surface of the plate and coupled to the passageway of the plate is adapted to receive the nozzle of the wall material source. The plate passageway directs the wall material dispensed from the source nozzle to the back surface opening to be delivered for application to the wall surface.
Patent CA-2202669-A1 (CA)
Title: Golf clubs
Inventor: SWASH HAROLD
IPC: A63B53/04
Filed: 1995-10-13
Abstract: The invention disclosed herein is directed to a golf putter with a ball-striking face that has a plurality of grooves formed therein. In the preferred embodiment, the grooves are equally spaced concentric grooves with a common center that lies along a line parallel to a line passing through the sweet spot of the putter.
Patent CA-2205952-A1 (CA)
Title: Machine a decouper, plier et assembler des parties de toles
Inventor: GARTH HARALD
IPC: B21D5/01
Filed: 1996-09-12
Abstract: L'invention concerne une machine à découper et à plier (10) qui présente des supports horizontaux supérieur et inférieur (18,16) dans chacun desquels sont logées deux chambres longitudinales (80) qui aboutissent aux côtés opposés des supports horizontaux (16,18) par de larges fentes longitudinales (86). Sur les deux faces latérales des supports horizontaux (16,18), sont fixés des systèmes à chariot (26) portant chacun un engrenage angulaire (36) encapsulé dans un carter d'engrenage, l'engrenage angulaire faisant saillie dans la chambre longitudinale (80) correspondante à travers la fente longitudinale (86). Les engrenages angulaires (36) de chaque chambre longitudinale (80) présentent des passages coaxiaux au contour polygonal. Un arbre moteur (28) de forme polygonale correspondante est inséré dans l'engrenage angulaire (36) de chaque canal longitudinal (80), reliant ainsi les systèmes à chariot (26) l'un à l'autre. Tous les paliers des roues dentées de l'engrenage angulaire (36) et de l'arbre de sortie du système à chariot (26) sont disposés dans le module composé du système à chariot (26) et de l'engrenage angulaire (36). L'arbre moteur (28) est supporté par l'engrenage angulaire (36) et ne nécessite, par conséquent, aucun logement propre dans les supports horizontaux (16,18) du carter de la machine (14).