baber/WOPTO huggingface dataset:
Patent NZ-225343-A (NZ)
Title: 3,5-dihydroxycarboxylic acids, corresponding lactones, and medicaments
Inventor: WESS GUNTHER
IPC: C07C47/00
Filed: 1988-07-08
Abstract: 3,5-dihydroxycarboxylic acids of formula (I) and their lactones of formula (II) are new: A-B = CH-CH or C=C; X-Y = CH2CH2 or CH=CH; R1 and R2 are each up to 20C, opt. unsatd., alkyl (opt. substd. by 1-6C alkoxy or OCOR5); 3-7C cycloalkyl; phenyl, thiophene, furan or naphthalene residue (these all opt. substd. by 1-3 of halo, 1-6C alkyl or alkoxy, 3-7C cycloalkyl or OCOR5) or pyridyl, opt. substd. by 1-3, 1-4C alkyl; R5 = 1-8C alkyl; R3 = up to 8C alkyl (opt. unsatd.); benzyl, phenyl, thiophene, furan or naphthalene residue (all opt. substd. as above), or 3-7C cycloalkyl; R4 = H, 1-8C alkyl, metal cation, ammonium ion, phenyl, benzyl or 2,3-dihydroxypropyl. Also new are the intermediates of formula (III), (IV), (VI), (VII), (VIII), (IX) or (XII): Q-X-Y-CHO (III); Q-X-Y-CHOH-CH2-CO-CH2-COOR4 (IV); Q-Z; Z = -X-Y-CN (cpds. (VI)); -CHO (cpds. (VII)); -CH2OH (cpds. (VIII)); or COOR7 (cpds. (IX)); R4 = 1-8C alkyl; R7 = protecting gp.; Q = a gp. of formula (i).
Patent NZ-226731-A (NZ)
Title: Cassette for packaging book-binding strips
Inventor: TIPPS BARNEY A
IPC: B42B5/00
Filed: 1988-10-26
Abstract: For convenient packaging of plastic bookbinding strips (21), cassettes are provided. The end edges of each strip are received in channels formed in opposed side rails (31). The rails engage adjacent either end the depending legs of transverse spacer bars. The spacer bars have plural sockets to engage projections on the upper ends of the legs so that the spacing between side rails may be varied to accommodate strips of different lengths - e.g., 8 1/2 inches, 11 inches, etc. Different length legs may be used to accommodate different length studs formed on the strips. By eliminating the legs entirely, flat female binding strips may be packaged in the cassette. A detent (67) is provided in the ends of the rails preventing removal of strips until the detent is bent out of position. The cassette is especially useful in equipment which mechanically assembles punched sheets and strips preparatory to binding a book in a binding machine.
Patent NZ-230174-A (NZ)
Title: Plant microbicidal composition comprising a pyrrole derivative and a triazole derivative
Inventor: NEVILL DAVID JOHN
IPC: A01N43/653
Filed: 1989-08-02
Abstract: The combination of the plant microbicide 3-cyano-4-(2,3-dichlorophenyl)-pyrrole ("fenpiclonil") with the plant microbicide 1-{2-[2-chloro-4-(4-chlorophenoxy)-phenyl]-4-methyl-1,3-dioxolan-2-ylm ethyl}-1H-1,2,4-triazole results in a synergistrically enhanced activity in the control of plant diseases. Plant microbicidal compositions based on such combinations are especially suitable for treating seed.
Patent NZ-236798-A (NZ)
Title: Capsule-like dosage form comprising a caplet core comprising a medicament and having two undercoats and a smooth, uniform, bubble-free outercoat; preparation thereof
Inventor: BATISTA MARLI F
IPC: A61K9/20
Filed: 1991-01-16
Abstract: A simulated capsule-like medicament comprising a dual subcoating comprising an initial subcoating of a water soluble film forming polymer, e.g. povidone and a secondary subcoating of a mixture of two soluble film forming polymers, e.g. povidone and hydroxypropyl methylcellulose and a hydrophobic plasticizer, e.g. castor oil, which provides for a smooth uniform and substantially bubble free outer coating, e.g. gelatin, for the capsule-like medicament; and a process of making such medicaments.
Patent NZ-241039-A (NZ)
Title: Methylenebisphosphonic acid ester amide derivatives and pharmaceutical compositions
Inventor: HANHIJARVI HANNU
IPC: A61P43/00
Filed: 1991-12-18
Abstract: PCT No. PCT/FI91/00396 Sec. 371 Date Oct. 20, 1993 Sec. 102(e) Date Oct. 20, 1993 PCT Filed Dec. 18, 1991 PCT Pub. No. WO92/11268 PCT Pub. Date Jul. 9, 1992.The invention relates to novel methylenebisphosphonic acid ester amide derivatives of general formula (I), in which formula W1, W2, W3 and W4 are independently the group OR1 or the group NR2R3 wherein R1, R2 and R3 independently are hydrogen or straight or branched, optionally unsaturated C1-C22-alkyl, optionally substituted, optionally unsaturated C3-C10-cycloalkyl, aryl, aralkyl or silyl SiR3, or the groups R2 and R3 form together with the adjacent nitrogen atom a 3 to 10-membered saturated, partly saturated or aromatic heterocyclic ring, wherein in addition to the nitrogen atom, there may be one or two heteroatoms from the group N, O and S, provided that in formula (I) at least one of the groups W1, W2, W3 and W4 is hydroxy and at least one of the groups W1, W2, W3 and W4 is amino group NR2R3, Q1 and Q2 are independently hydrogen, fluorine, chlorine, bromine or iodine, including the stereoisomers, such as the geometrical isomers and the optically active isomers, of the compounds, as well as the pharmacologically acceptable salts of the compounds.
Patent NZ-248155-A (NZ)
Title: Oxime ether derivatives and pesticidal compositions
Inventor: OBERDORF KLAUS
IPC: C07D333/32
Filed: 1993-07-15
Abstract: Substituted oxime ethers of the general formula I <IMAGE>  in which   R<1> denotes alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, cyanoalkyl, alkoxycarbonylalkyl, arylalkyl, heteroarylalkyl, arylalkenyl or aryloxyalkyl, the aromatic or heteroaromatic ring optionally being substituted, R<2> and R<3> denote hydrogen, alkyl, haloalkyl, alkoxy, haloalkoxy, halogen, cyano or nitro, R<4> denotes hydrogen, alkyl, cycloalkyl, haloalkyl or aryl, the aromatic ring optionally being substituted and R<5> and R<6> are identical or different and denote hydrogen or alkyl, and   X denotes CH or N, and fungicides and pesticides containing these compounds.
Patent NZ-250277-A (NZ)
Title: Absorbent article; cuff regions made up of a layer of hydrophillic material on top of the outer sheet
Inventor: CORREA MAURO FEIJO COSTA
IPC: A61F13/15
Filed: 1993-11-24
Abstract: The present invention of a disposable intimate feminine absorbent with lateral regions or cuffs for containing liquids, which tend to assume a vertical position when the absorbent assumes, in use, an anatomical arched configuration. <IMAGE>
Patent NZ-280026-A (NZ)
Title: Method for soft tissue augmentation by injection of a matrix of rounded ceramic particles
Inventor: HUBBARD WILLIAM G
IPC: A61L27/46
Filed: 1993-02-05
Abstract: Disclosed is the use in the manufacture of a medicament for soft tissue augmentation in a mammalian species, of a matrix of rounded, substantially spherical, biocompatible, substantially non-resorbable, finely divided ceramic particles close to or in contact with each other, the particles being greater than 15 microns in diameter and up to 150 microns in diameter. The medicament is for particular use in soft tissue augmentation of the urethral sphincter for treatment of urinary incontinence. (62) Divided out of 249381
Patent NZ-282404-A (NZ)
Title: Separation of r-(+)- and s-(-)-amlodipine enantiomers
Inventor: SPARGO PETER LIONEL
IPC: C07D211/90
Filed: 1995-03-06
Abstract: A method for the separation of R-(+)- and S-(-)-isomers of amlodipine (I) from mixtures thereof, which comprises the reaction of the mixture of isomers with either L- or D-tartaric acid in an organic solvent containing sufficient dimethyl sulphoxide (DMSO) for the precipitation of, respectively, a DMSO, solvate of an L-tartate salt of R-(+)-amlodipine, or a DMSO solvate of a D-tartrate salt of S-(-)-amlodipine.
Patent NZ-283398-A (NZ)
Title: Radio system transmission mode according to quality of channel
Inventor: DE SEZE FABRICE
IPC: H04B7/26
Filed: 1995-03-27
Abstract: PCT No. PCT/FR95/00381 Sec. 371 Date Sep. 24, 1996 Sec. 102(e) Date Sep. 24, 1996 PCT Filed Mar. 27, 1995 PCT Pub. No. WO95/27345 PCT Pub. Date Oct. 12, 1995A mobile radio system conveys frames between at least one mobile station and at least one base station, each frame comprising N time slots, a burst of data being transmitted in each time slot, and each time slot being associated with a separate call between a mobile station and a base station. For each call over a transmission channel, the quality of the transmission channel is analyzed and, on the, basis thereof, a selection is made between first and second modes of transmission. In the first mode of transmission data to be transmitted is organized in first blocks obtained by a first encoding of source blocks, each of the first blocks has a size greater than the content of (P-1) bursts, where P is an even number at least equal to 2, and the data of the same first block is distributed between at least P bursts. In the second mode of transmission the data to be transmitted is organized in second blocks each having a size less than or equal to the content of P/2 bursts, the data of the same second block is distributed into at most P/2 bursts, at least P/2 bursts are available relative to the first mode of transmission, and an automatic retransmission request mechanism is used to retransmit in the available bursts second blocks that are detected to have been received incorrectly. This second mode of transmission necessitates a quality of the transmission channel greater than that necessitated by the first mode of transmission.
Patent NZ-308228-A (NZ)
Title: Substituted 1,8-naphthyridine derivatives
Inventor: MURAOKA MASAMI
IPC: C07D471/04
Filed: 1996-05-28
Abstract: The specification describes naphthyridine derivatives represented by general formula (1) and acid-addition salts thereof, having the activity of inhibiting acyl CoA: cholesterol acyltransferases, and useful for preventing and treating hyperlipemia, arteriosclerosis and related diseases. In the above formula, ring A represents an optionally substituted pyridine ring; X represents -NR2-CO-; R2 represents hydrogen, alkyl, substituted alkyl, etc.; Z represents a bond, -NH-, C1-C2 alkylene, or -CH=CH-; Y represents optionally substituted alkyl, aryl, substituted aryl, etc.; and B represents optionally substituted alkyl, aryl, substituted aryl, etc. W represents hydrogen or -OR1; where R1 is an optionally substituted alkyl, alkenyl or alkynyl group
Patent NZ-309217-A (NZ)
Title: Ribavirin and interferon alpha for the treatment of hepatitis C
Inventor: ALBRECHT JANICE K
IPC: A61P31/14
Filed: 1996-05-15
Abstract: There is disclosed a method for administering an amount of alpha interferon in association with an amount of ribavirin effective to treat chronic hepatitis C infection with the absence or substantial reduction of side effects associated with administration of ribavirin and alpha interferon.
Patent NZ-310444-A (NZ)
Title: Novel dolastatin derivatives, their preparation and use
Inventor: HAUPT ANDREAS
IPC: A61K38/08
Filed: 1996-06-03
Abstract: A method for the preparation of novel peptides (Formula I) and their use in pharmaceutical compositions.  Such compositions containing said peptides offer improved therapeutic potential for the treatment of neoplastic disease. Peptides of Formula I have the general formula: 			R1R2N-CHX-CO-A-B-D-E-(F)t-K  Where: R1 is methyl, ethyl, or isopropyl; R2 is hydrogen, methyl, or ethyl; R1-N-R2 together may be a pyrrollidine ring; A  is a valyl, isoleucyl, leucyl, 2-tert-butylglycyl, 2-ethylglycyl, norleucyl or norvalyl residue B is a N-methyl-valyl, -leucyl, -isoleucyl, -norvalyl, -norleucyl, -2-tert-butylglycyl, -3-tert-butylalanyl, or -2-ethylglycyl residue; B is a prolyl, 3,4-dehydroprolyl, 4-fluoroprolyl, 4,4-difluoroprolyl, azetidine-2-carbonyl, homoprolyl, 3-methylprolyl, 4-methylprolyl, 5-methylprolyl, or thiazolidine-4-carbonyl residue; E  is a 3,4-dehydroprolyl, 4-fluoroprolyl, 3-methylprolyl, 4-methylprolyl, azetidine-2-carbonyl, or 4,4-difluoroprolyl residue; F is a valyl, 2-tert-butylglycyl, isoleucyl, leucyl, 2-cyclohexylglycyl, norleucyl, norvalyl, neopentylglycyl, alanyl, b-alanyl, or aminoisobutyroyl residue; X  is alkyl (preferably C2-5), cyclopropyl, or cyclopentyl; T  is 0 or 1 K is alkoxy (preferably C1-4), benzyloxy or an optionally substituted amino moiety.
Patent NZ-500175-A (NZ)
Title: Use of 6-hydroxy-2-(4-methoxyphenyl)-3-[4-(2-piperidinoethoxy)-phenoxy]benzo[b]thiophene or 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)-phenoxy]benzo[b]thiophene for treating Alzheimer's disease
Inventor: BRYANT HENRY UHLMAN
IPC: A61P25/28
Filed: 1998-04-07
Abstract: Use of a compound having the structure shown, wherein: R2 is hydroxy or methoxy, or a pharmaceutically acceptable salt (e.g. hydrochloride salt) or pro-drug thereof, in the manufacture of a medicament for treating Alzheimer's disease.
Patent NZ-501185-A (NZ)
Title: Disinfectant compositions containing active ingredients against pseudomonas, an alkylpolysaccaharide surfactant, aryl alcohol and alkyl alcohol
Inventor: GLUCK BRUNO ANTHONY
IPC: C11D1/00
Filed: 1998-05-07
Abstract: This antiseptic cleansing composition effective against Pseudomonas comprises: a)   an antimicrobial agent, selected from chlorhexidine, chlorhexidine salt, chlorophenol derivative, octenidindihydrochloride (CH3-(CH2)7-NHON-(CH2)10-NO-NH(CH2)7-CH2 or any other salt thereof, and quaternary ammonium compounds; b)   an effective amount of an alkylpolysaccharide which contains one or more sugar units selected from the group consisting of maltose, arabinose, xylose, mannose, galactose, gulose, idose, talose, allose, altrose, sucrose, fructose, sorbose, levulose, lactose, allulose, tagatose, alloheptulose, sedoheptulose, glucoheptulose, mannoheptulose, guloheptulose, idoheptulose, galactoheptulose, taloheptulose and derivatives thereof; and c)   at least one alkyl alcohol and at least one aryl alcohol.
Patent NZ-501199-A (NZ)
Title: Glial cell line-derived neurotrophic factor receptors (BDNFR-beta)
Inventor: IBANEZ CARLOS F
IPC: A61K48/00
Filed: 1998-05-04
Abstract: Isolated GDNFR-b and isolated compounds comprising the amino acid sequence of SEQ ID NO:2, SEQ ID NO:9.  The isolated nucleic acid encoding the amino acids having the sequence of SEQ ID NO: 2, 5, 9 and 10.
Patent NZ-507248-A (NZ)
Title: Compositions and method for treating keratinous fibres and, in particular, for protecting human hair from UV sunlight
Inventor: KRUGER MARCUS
IPC: A61K8/06
Filed: 1999-02-20
Abstract: Agents containing at least 6 wt. % oil components and at least one non-ionogenic emulsifier. The agents take the form of a microemulsion with an average droplet size of less than 400 nanometers and contain a UV radiation-absorbing component A of general formula U-Q, wherein U represents a UV radiation-absorbing group and Q represents a group containing at least one quarternary ammonium function. These agents are suited to protecting keratinous fibres, especially human hair, against UV radiation.
Patent NZ-517836-A (NZ)
Title: Feeding arrangement for individual feeding of timber pieces
Inventor: GUNNARSSON CENNETH
IPC: B07C5/14
Filed: 2000-09-11
Abstract: A feeder arrangement for the individual feeding of timber pieces (10) to a downwardly moving conveyor (2) includes an incoming conveyor (7) and projecting carriers (23) on the downwardly moving conveyor (2). The incoming conveyor (7) is disposed for the feeding of timber pieces (10). The carriers (23) incline obliquely downwards and outwards from the downwardly moving conveyor (2). A curved guide space (21) is disposed to overlap, with a lower end portion, an upper portion of the downwardly moving conveyor (2). The angle of curvature of the guide space (21) is so great that the upper side of a timber piece (10) which comes to guide space (21) will be turned to face downwards when the timber piece (10) rests on a carrier (23). The incoming conveyor (7) has an end portion which is turned to face towards the guide space (21) and which is approximately horizontal.
Patent NZ-519938-A (NZ)
Title: Non-sticking container for ice cream
Inventor: SAN MARTIN JESUS
IPC: B65D3/28
Filed: 2000-08-17
Abstract: An improved container for ice confectioneries particularly for use in dispensing equipment, of the type having a cylindrical or prismatic body, and preferably made from cardboard, in which the body has protrusions for preventing frost or ice that forms on its outer surface from causing adjacent, stacked containers from sticking together, thus enabling proper dispensing of the containers from automated dispensing or vending machines
Patent NZ-526747-A (NZ)
Title: A delivery device
Inventor: JENNINGS DOUGLAS IVAN
IPC: A61M15/00
Filed: 2001-12-20
Abstract: A manually actuated delivery device for the delivery of a dose of liquid comprising a housing (1) which includes an outlet, through which liquid, in use is delivered. An actuating member (2) is moveably disposed relative to the housing between a first position and a second position, the user moving the actuating member into the second position to actuate the delivery device. A liquid delivery assembly (3) is located at least partly within the housing, the liquid delivery assembly comprising a liquid delivery unit (4) a carrier unit (5) for the liquid delivery unit and a coupling member (6), which couples the movement of the actuating member and the carrier unit. The movement of the carrier unit activates a counting mechanism (7a, 7b) which indicates how many doses have been delivered.
Patent NZ-526926-A (NZ)
Title: New film coating composition that provides a latex dispersion for coating pharmaceutical formulations
Inventor: LOFROTH JAN-ERIK
IPC: A61K9/50
Filed: 2002-12-18
Abstract: A film coating composition suitable for use in coating pharmaceutical formulations to provide modified release is disclosed, wherein the composition comprises a dispersion which includes: (a) an acrylic polymer; (b) a vinyl acetate polymer; and (c) a water-containing liquid. The film coat is useful for the achievement of modified release from pharmaceutical formulations such as tablets and pellets.
Patent NZ-528678-A (NZ)
Title: Heat pump with refrigerant from high pressure side passed through heat exchanger to prevent ice formation on evaporator
Inventor: INNES RODNEY MITCHELL
IPC: F25B47/02
Filed: 2003-10-06
Abstract: In order to reduce or eliminate ice formation on external surfaces of a heat pump evaporator 4 refrigerant from the high pressure side is passed (via line 17) to heat exchanger 6a. Controller 8 is used to determine (indirectly) whether ice formation will occur by sensing suction pressure at 11 so as to control refrigerant flow through line 17.
Patent NZ-528751-A (NZ)
Title: Vial adapter having a needle-free valve for use with vial closures of different sizes
Inventor: LEINSING KARL R
IPC: A61M39/04
Filed: 2003-02-07
Abstract: A vial adapter having a needle-free valve, a sharpened cannula used to perforate a vial's rubber stopper, and a circular array of claws of different lengths to engage vial closures of different diameters. The array of claws includes a first set of claws each having a first length extending inwardly from the periphery of the housing of the adapter and a second set of claws alternating with the first set of claws and each having a longer length. The second set of claws are mounted so that they deflect and plastically deform out of the way in the case where the adapter is engaged with a vial that exceeds a predetermined size. The housing includes a shroud that is at least as long as the sharpened cannula to protect medical personnel who use the adapter from inadvertent punctures. The needle-free valve includes a resiliently deformable piston element with a naturally open bore. The interior of the piston provides a fluid flow path through the adapter. In one embodiment, the first set of claws of the adapter may be used with a vial closure of at approximately 20 mm in diameter and the second set of claws may be used with a vial closure of approximately 13 to 17 mm in diameter.
Patent NZ-532493-A (NZ)
Title: Washing platform with a raised central work surface surrounded by a trough
Inventor: PIATT JAMES M
IPC: A47K1/04
Filed: 2002-10-25
Abstract: A washing platform (12) has a generally flat upper work surface (24). A spout (18) is located adjacent the washing platform and provides a stream of fluid which impinges the work surface. A bowl can be removably placed on the washing platform to receive water from the spout. The bowl has an aperture (44) through the bottom and a gasket (46) which is attached to an exterior surface of the bowl around the aperture. When the bowl is placed on the work surface, the gasket provides a seal that inhibits flow of fluid there between until a user lifts the bowl to drain the water there from.
Patent NZ-534253-A (NZ)
Title: Container closures
Inventor: VON SPRECKELSEN HENNING
IPC: B29C65/02
Filed: 2003-01-16
Abstract: A closure for a container comprises a spout (22) containing a plastics coated foil (40) that is welded via one face to an inside flange (30) of the spout and by means of a depending portion (42) on its opposite face to a side wall (10) of the container so that forces on the weld between foil portion (42) and the container when the closure is opened are in shear rather than in tension. The closure can be used with a PET bottle or with other types of plastics or plastics coated containers.
Patent NZ-537771-A (NZ)
Title: Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
Inventor: JASTI VENKATESWARLU
IPC: A61P25/16
Filed: 2003-06-19
Abstract: Disclosed are tetracyclic arylcarbonyl indoles of the general formula (I), their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This disclosure also relates to processes for preparing such compounds of general formula (I), compositions containing effective amounts of such a compound and the use of such a compound/composition in therapy.
Patent NZ-538197-A (NZ)
Title: 6,7-Dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
Inventor: LAUFERSWEILER MATTHEW JOHN
IPC: C07D495/20
Filed: 2003-03-18
Abstract: Disclosed is a compound of formula (I) wherein: R1 is aryl or heteroaryl; R2 is independently selected from H, -(CH2)jO(CH2)nR8, -(CH2)jNR9aR9b, -(CH2)jCO2R10, -(CH2)jOCO2R10, -(CH2)jCON(R10)2, and two R2 units can be taken together to form a carbonyl unit; R8, R9a, R9b and R10 are each independently H, alkyl and mixtures thereof; R9a and R9b can be taken together to form a carbocyclic or heterocyclic ring comprising form 3-7 atoms; two R10 units can be taken together to form a carbocyclic or heterocyclic ring comprising from 3 to 7 atoms; j and n are 0-5 Z is O, S NR11, or NOR11 wherein R11 is H or alkyl; R4b is aryl or heteroaryl.
Patent NZ-546430-A (NZ)
Title: Liquid vaccines for multiple meningococcal serogroups
Inventor: CONTORNI MARIO
IPC: A61K39/102
Filed: 2004-10-04
Abstract: Disclosed is an aqueous immunogenic composition capable of inducing an immune response that is (a) bactericidal against at least serogroup W135 of N. meningitidis and protective against H. influenzae type b disease, wherein the composition comprises: (i) a serogroup W135 capsular saccharide antigen conjugated to a diphtheria toxoid; and (ii) a conjugated H. influenzae type b (Hib) capsular saccharide antigen.
Patent NZ-551626-A (NZ)
Title: Antibodies that bind to p-selectin glycoprotein ligand 1
Inventor: LIN RONG-HWA
IPC: A61K39/395
Filed: 2005-05-10
Abstract: Disclosed is an isolated antibody, comprising a first immunoglobulin chain and a second immunoglobulin chain, wherein, the first immunoglobulin chain is a light chain comprising a specific amino acid sequence and the second immunoglobulin chain is a heavy chain comprising a specific amino acid sequence. Furthermore, the disclosed antibody is capable of binding specifically to amino acid residues 115-126 of human P-Selectin Glycoprotein Ligand-1 (PSGL-1) without interfering with binding between PSGL-1 and P-Selectin, wherein the antibody, upon binding to PSGL-1 on an activated T-cell, induces death of the activated T-cell.