baber/WOPTO huggingface dataset:
Patent PT-777652-E (PT)
Inventor: BUTLER TODD W
IPC: A61P25/04
Filed: 1995-05-18
Abstract: PCT No. PCT/IB95/00380 Sec. 371 Date Feb. 13, 1996 Sec. 102(e) Date Feb. 13, 1996 PCT Filed May 18, 1995 PCT Pub. No. WO96/06081 PCT Pub. Date Feb. 29, 1996This invention relates to compounds of formula (I), or pharmaceutically acceptable acid addition salts thereof, wherein: (a) R2 and R5 are taken separately and R1, R2, R3 and R4 are each independently hydrogen, (C1-C6) alkyl, halo, CF3, OH or OR7 and R5 is methyl or ethyl; or (b) R2 and R5 are taken together, forming a chroman-4-ol ring, and R1, R3 and R4 are each independently hydrogen, (C1-C6) alkyl, halo, CF3, OH or OR7; and R6 is a substituted piperidinyl, pyrrolidinyl or 8-azabicyclo(3.2.1)octanyl derivative; provided that (a) when R2 and R5 are taken separately, at least one of R1, R2, R3 and R4 is not hydrogen; and (b) when R2 and R5 are taken together, at least one of R1, R3 and R4 is not hydrogen; pharmaceutical compositions thereof; and methods of treating mammals suffering from stroke, spinal cord trauma, traumatic brain injury, multiinfarct dementia, CNS degenerative diseases such as Alzheimer's disease, senile dementia of the Alzheimer's type, Huntington's disease, Parkinson's disease, epilepsy, amyotrophic lateral sclerosis, pain, AIDS dementia, psychotic conditions, drug addictions, migraine, hypoglycemia, anxiolytic conditions, urinary incontinence and an ischemic event arising from CNS surgery, open heart surgery or any procedure during which the function of the cardiovascular system is compromised with a compound of formula (I) hereinabove or a pharmaceutically acceptable salt thereof.
Patent PT-797437-E (PT)
Inventor: SHIRE MARY
IPC: C07D209/46
Filed: 1995-11-20
Abstract: Novel imide/amide ethers are inhibitors of tumor necrosis factor alpha  and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 1-Phthalimido-1-(3',4'-dimethoxyphenyl)propan-1-ol.
Patent PT-729761-E (PT)
Inventor: IWATSCHENKO PETER
IPC: A61M39/08
Filed: 1996-01-18
Abstract: Tubing (10), for a medical container, has an outer layer (12) of ethylene-vinyl acetate copolymer and an inner layer (14) of polyurethane, pref formed by co-extrusion. Also claimed is a medical container, esp. for enteral or parenteral feeding, with an attachment of the tubing. Pref the tubing is sterilised with ethylene oxide or by irradiation. Pref the container consists of ethylene-vinyl acetate copolymer and is welded to the outer layer (12) of the tubing (10), the inner layer (14) pref being adhesively bonded to a connector or other component.
Patent PT-839142-E (PT)
Inventor: LI HUI-YIN
IPC: C07D311/56
Filed: 1996-07-10
Abstract: The present invention provides a novel process for making compounds of formula (2a or 2b) or pharmaceutically acceptable salts thereof, wherein R1 is selected from the group consisting of phenyl and phenyl substituted with at least one group selected from NO2 and halogen, R2 is H; R3 is selected from the group consisting of C1-4 alkyl, phenyl, and benzyl; and, R4 is selected from the group consisting of H and halogen; which comprises the steps of: a) oxidizing a racemate of formula (2) or a salt thereof to form a dehydro-compound of formula (3), wherein R5 is selected from the group consisting of H, CH3, benzyl, C2-8 acyl, Na, Li and K; and, b) asymmetrically hydrogenating a compound of formula (3) in the presence of a chiral phosphine catalyst to form a compound of formula (2a or 2b).
Patent PT-842174-E (PT)
Inventor: RIEU JEAN-PIERRE
IPC: A61P9/10
Filed: 1996-07-25
Abstract: PCT No. PCT/FR96/01176 Sec. 371 Date Jan. 26, 1998 Sec. 102(e) Date Jan. 26, 1998 PCT Filed Jul. 25, 1996 PCT Pub. No. WO97/05134 PCT Pub. Date Feb. 13, 1997Substituted N-heterocyclyl-1-aryloxyalkyl-4-piperldineamines of formula (I) wherein each of R1 to R4, which are the same or different, is hydrogen, optionally branched C1-4 alkyl, optionally branched C1-4 alkyloxy, halo, nitro, hydroxy, or trifluoromethyl or trifluoromethoxyl; R5 is hydrogen, optionally branched C1-6 alkyl, optionally branched C7-12 phenylalkyl optionally substituted on the phenyl by one or more radicals having the same definition as R1; W and X are oxygen or sulphur; Y is C2-6 polymethylene or -CH2-CH(OH)-CH2-; and n is 0 or 1; and pure R or S isomers of said compounds, where applicable, as well as mixtures thereof, as well as therapeutically-acceptable organic or inorganic salts and hydrates of the compounds and a method for preparing the compounds and their use as drugs are all disclosed.
Patent PT-942702-E (PT)
Inventor: FELLINGER ANDREAS
IPC: A61B50/30
Filed: 1997-10-10
Abstract: A storage device for medical swabs having an envelope for the latter is characterized in that the envelope is formed by adjacently disposed chambers which are sealed bacteria-tight for the swabs. The size of the chambers is determined by the number and the size of the swabs kept in stock in each of them, it being intended, so ensure absolute sterility, that only one swab should be kept in stock in one chamber, so that each swab can be removed sterilized from the storage device. The envelopes can be kept in stock rolled up or concertinaed.
Patent PT-958421-E (PT)
Inventor: MARCHETTI LUIGI
IPC: D05B73/12
Filed: 1997-04-09
Abstract: The equipment comprises in combination: a twin needle (15, 17) fed with two needle threads (F1, F2); an upper looper (30) fed with a looper thread (F3), and a lower spreader (31); a throat plate (36) with two slots (38, 40) for the needles (15, 17) and the stitch finger (42) on the line of the cut (T) of increased width (D); and a thread-pulling arm (25) for pulling off an increased amount of the thread (F3) for the looper at each angular stroke.
Patent PT-910274-E (PT)
Inventor: PEDERSEN THOR
IPC: A47K11/02
Filed: 1997-07-10
Abstract: PCT No. PCT/SE97/01252 Sec. 371 Date Jan. 21, 1999 Sec. 102(e) Date Jan. 21, 1999 PCT Filed Jul. 10, 1997 PCT Pub. No. WO98/02079 PCT Pub. Date Jan. 22, 1998An electric toilet comprising a cabinet or housing (10), an opening (16) in the top side of the cabinet, a lid (14) assigned to the opening (14), an upper bowl (18) arranged inside the opening, which bowl is openable downwards, a combustion chamber (32) arranged beneath the upper bowl (18) with a combustion space (34) and provided with an opening (36) directed upwards, assigned to which opening is a lid (38), heating coils (44) arranged in the combustion space (34) and an evacuation device (48, 50, 52) connected to the combustion space (34). The invention is characterized in that at least the combustion space's (34) lower part is formed principally spherically and that the heating coils (44) are arranged in the upper part of the combustion space round its circumference.
Patent PT-864286-E (PT)
Inventor: SCHEDEL WOLFGANG
IPC: A47K3/16
Filed: 1998-02-21
Abstract: The device is intended for centering bathtubs and shower trays in a support made of rigid foam. An angle piece (1), the arms (1a, 1b) of which have a horizontal thickness adapted to the distance between the inner edge of a bathtub or shower-tray edge bend and the outer wall of the bathtub or shower-tray support, is provided on its inner vertex (3) with a profiled projection (4) insertable into a groove provided in the corner region of the bathtub or shower-tray support.
Patent PT-996451-E (PT)
Inventor: MARCIANI DANTE J
IPC: A61K47/48
Filed: 1998-05-20
Abstract: The present invention is directed to novel chemical compounds in which a lipophilic moiety such as a lipid, fatty acid, polyethylene glycol or terpene is covalently attached to a non-acylated or desacylated triterpene saponin via a carboxyl group present on the 3-O-glucuronic acid of the triterpene saponin. The attachment of a lipophile moiety to the 3-O-glucuronic acid of a saponin such as Quillaja desacylsaponin, lucyoside P, or saponin from Gypsophila, Saponaria and Acanthophyllum enhances their adjuvant effects on humoral and cell mediated immunity. Additionally, the attachment of a lipophile moiety to the 3-O-glucuronic acid residue of non- or des-acylsaponin yields a saponin analog that is easier to purify, less toxic, chemically more stable, and possesses equal or better adjuvant properties than the original saponin.
Patent PT-984019-E (PT)
Inventor: BRONK BRIAN SCOTT
IPC: C07H17/08
Filed: 1999-07-29
Abstract: This invention relates to compounds of the formula <CHEM> and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial agents that may be used to treat various bacterial infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
Patent PT-1059844-E (PT)
Inventor: ALLAN PILLAY
IPC: A01M29/12
Filed: 1999-03-05
Abstract: Microbicidal compositions containing synergistic combinations of propiconazole, (RS)- 1-2-[(2, 4-dichlorophenyl)-2- propyl-1,3-dioxanlan- 2ylmethyl]-1H-1,2, 4-triazole, and 2-mercaptobenzothiazole or alkali metal salt thereof are described. The propiconazole and 2-mercaptobenzothiazole or an alkali metal salt thereof are applied to a substrate or aqueous system subject to the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of propiconazole and 2-mercaptobenzothiazole or an alkali metal salt thereof is particularly useful as microbicidal in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.
Patent PT-1126755-E (PT)
Inventor: VERMEULEN ARNOLDUS HENRICUS AN
IPC: A01G9/14
Filed: 1999-11-01
Abstract: The invention relates to a building comprising a skeleton which is formed by a number of uprights and beams connecting the uprights, and a cover layer of relatively thin material arranged on the outside of the skeleton, wherein a substantially horizontally running gutter is arranged along at least one edge of the cover layer, which gutter has means protruding inside the cover layer for collecting condensed moisture flowing along the inner side of the cover layer. These condensation collecting means can be in liquid connection with a part of the gutter protruding outside the cover layer, and can comprise a condensation channel extending parallel to the gutter, wherein the liquid connection is then formed by one or more draining openings arranged in the bottom of the condensation channel. The gutter can herein be of U-shaped cross-section and the condensation channel can extend to the inside of the U-shape. Further according to the invention the beams are formed by beam members having a cross-section with a flat side directed toward the inside of the building and a curved side located opposite thereto. These beam members then have a closed cross-section wherein the flat and curved side are connected by two standing sides and the distance between the standing sides is smaller than the distance between the flat and curved side.
Patent SG-97890-G (SG)
Title: Antiparasitic non-aqeous formulation containing an avermectin or milbemycin
IPC: A61K47/00
Filed: 1990-12-10
Abstract: Ivermectin, an antiparasitic agent which is insoluble and unstable in water, and other avermectin and milbemycin compounds, are formulated in glycerol formal and propylene glycol or in water and propylene glycol. These liquid formulations are suitable for parenteral administration for the treatment of parasitic infections and demonstrate improved efficacy and a broadened spectrum over previous formulations.
Patent IE-840158-L (IE)
Title: Pharmaceutical composition.
IPC: A61K31/15
Filed: 1984-01-24
Abstract: Utilisation as antibacterial medicaments of halogenobenzophenone-oxime derivatives having the formula (I), wherein R is a branched hydrocarbonated chain C3-C8 alkyl group, and Ar is a halogenophenyl group having the formula (II), wherein R1 is F, Cl or Br, and R2 and R3, which may be identical or different represent each H, F, Cl or Br.
[WO8402844A1]
Patent IE-790311-L (IE)
Title: 2-phenylimino-imidazolidines
IPC: A61P9/00
Filed: 1979-02-16
Abstract: Compounds of the formula <IMAGE> wherein R is 2-bromo-4,5-dihydroxy-phenyl; 3-chloro-4-hydroxy-phenyl; 4-bromo-2,5-dihydroxy-phenyl; 3,5-dihydroxy-phenyl; 5-chloro-2,4-dihydroxy-phenyl; 3-hydroxy-4-methyl-phenyl; 2,6-dibromo-4-hydroxymethyl-phenyl; 3,5-dibromo-4-amino-phenyl; 3-methylmercapto-phenyl; 3,4,5-trihydroxy-phenyl; or 3-bromo-4-fluoro-phenyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
[US4250186A]
Patent IE-35269-L (IE)
Title: Detergent composition with controlled foaming
IPC: C11D3/00
Filed: 1971-05-20
Abstract: 1304803 Low foam detergent composition PROCTER & GAMBLE CO 20 May 1971 [20 May 1970] 16015/71 Heading C5D A detergent composition comprises (a) 2- 30% of a non-cationic surface active agent, (b) 0À05-5% of a suds controlling agent selected from finely divided silenated silica, silicones and finely divided by dropholic polymers of ethylene, fluoroethylene, butylene, isobutylene and styrene and (c) 0À5-8% of either (i) a homopolymer of methyl vinyl either, ethyl vinyl ether, vinyl acetate, vinyl propionate or vinyl pyrrolidone or a copolymer of 2 or more of these monomers having a molecular weight of 5,000- 50,000 or (ii) a copolymer of maleric anhydride and ethylene, styrene or a C 1-4 alkyl vinyl ether having a molecular weight of 10,000-300,000 or a water-soluble alkali metal salt thereof or (iii) a polyethylene glycol of molecular weight 1,000- 50,000. The composition may also include a builder and a peroxy compound. Ingredients specified include: surface active agents sodium C 11À8 alkyl benzene sulphonate, tallow fatty alcohol Sulphate (sodium Salt), Sodium coconut oil fatty alcohol sulphate, 3-(C 14À 8 alkyl dimethyl ammonio)-propane-1-sulphonate, 3-(C 14À8 alkyl dimethyl ammonio)-2-hydroxypropane-1- sulphonate, 3 - (N,N-dimethyl - N - tetradecylammonio) - propane-1-phosphate, tallow alcohol ethylene oxide adduct, stearyl dimethylamine oxide, laruyl-dhosphine oxide; suds controlling agents: silanated silica, polydimethyl siloxane, polymethyl pheuyl siloxane, component (c): sodinm salt of vinyl acetate-vinyl pyrrolidone copolymer, sodium salt of maleic anhydride-styrene copolymer, sodium salt of maleio anhydridevinyl methyl ether copolymer, sodium salt of maleic anhydride-vinyl butyl ether copolymer, builders: trisodium ethylene-1-hydroxy -1,1- diphosphonate, sodium tripolyphosphate, chlorinated trisodium phosphate, sodium chloride, sodium silicate, sodium sulphate, trisodium nitrilo triacetate, sodium ethylene diamine tetra-acetate, peroxy-compounds: sodium perborate, other ingredients: hydrogenated fatty acids, carboxymethyl cellulose, sodium toluene sulphonate, monoethanolamine, silica, amylase and protease enzymes, brighteners, dyes, perfumes and water.
[GB1304803A]
Patent IE-40048-L (IE)
Title: Improved process for producing alpha-6- deoxy- tetracyclines.
IPC: C07C231/00
Filed: 1974-03-27
Abstract: The catalytic hydrogenation of 6-methylenetetracyclines, or salts of these compounds, in a reaction-inert solvent medium containing a catalytic amount of rhodium metal to which a phosphine and a promoter is added.
[US3954862A]
Patent IE-39129-L (IE)
Title: Producing flooring plaster by the flooding technique.
IPC: E04F15/12
Filed: 1974-04-11
Abstract: In the process for producing a plaster flooring having a flat and smooth surface by the flooding technique, in which an inorganic binder is made up into a fluid paste by the addition of water and said fluid paste is applied to a surface to be covered, the improvement which comprises providing a water-absorbent layer on said surface to be covered prior to application of said fluid paste.
[US4005954A]
Patent IE-39754-L (IE)
Title: Itaconic acid and derivatives.
IPC: C07C57/00
Filed: 1974-05-02
Abstract: 1418451 ltaconic acid and derivatives SNAMPROGETTI SpA 1 May 1974 [9 May 1973] 19195/74 Heading C2C Compounds of formula wherein R and R<SP>1</SP> are hydrogen atoms, a hydrocarbon radical, and either each of X and X<SP>1</SP>, which can be the same or different is -CN, -COOR<SP>2</SP>, -COOM, or -CONH 2 where M is a monovalent metal atom or represents part of a metal atom of valency at least 2 and R<SP>2</SP> is a hydrogen atom or a hydrocarbon radical, or X and X<SP>1</SP> represent a divalent radical and with the two carbon atoms attached thereto form a heterocyclic ring with five atoms, are prepared by reacting formaldehyde or a precursor therefor with a compound An example describes the preparation of potassium itaconate by reacting diethyl succinate with trioxane in the presence of a tert.-butanol solution of potassium tert.-butanolate.
[GB1418451A]
Patent FI-812582-L (FI)
Inventor: LIN WEN-PING
IPC: A63H33/04
Filed: 1981-08-21
Abstract: A set of building blocks readily assembled to form a variety of houses comprises several flexible wall elements, flexible roof elements, roof forming elements, roof connecting elements, cubic elements, and base boards which can be connected side by side to construct a base as a ground member of the houses. The wall elements can be bent into different configurations so as to act as side walls at one's desire.
Patent FI-821454-L (FI)
Inventor: GOTTLIEB KLAUS
IPC: C07C41/42
Filed: 1982-04-27
Abstract: A process for producing sec-butanol and sec-butyl tert-butyl ether from butane comprises: (a) partially isomerizing n-butane to produce a mixture of n-butane and isobutane; (b) catalytically dehydrogenating said butanes to produce a mixture containing at least butene-1, isobutene and butadiene; (c) selectively hydrogenating butadiene and converting butene-1 to butene-2; (d) etherifying isobutene contained in the dehydrogenation reaction mixture with sec-butanol to form a mixture of sec-butyl tert-butyl ether and unreacted hydrocarbons; (e) converting butene-2 from the unreacted hydrocarbon mixture by hydration to produce sec-butanol; (f) recycling said sec-butanol to the etherification step; recovering said sec-butyl tert-butyl ether.
Patent IE-34617-L (IE)
Title: Bipyridylium salts.
IPC: C07D213/20
Filed: 1970-10-06
Abstract: 1308048 1,1<SP>1</SP>-Disubstituted-4,4<SP>1</SP>-bipyridylium salts IMPERIAL CHEMICAL INDUSTRIES Ltd 2 Oct 1970 [21 Oct 1969] 51557/69 Heading C2C 1,1<SP>1</SP>-Disubstituted-4,4<SP>1</SP>-bipyridylium salts are prepared by reacting an N-substituted pyridinium salt having a carboxyl group or salt thereof in the 4-position with cyanide ions and subsequently oxidizing the resulting interaction product. The cyanide ions may be added in the form of a cyanide, preferably sodium cyanide, the reaction preferably being carried out under basic conditions at from 25 to 120‹ C. in a polar aprotic solvent. The oxidizing agent may be air, oxygen or an inorganic oxyacid anhydride and is preferably sulphur dioxide, the oxidation is preferably carried out in acid conditions. The interaction product is preferably isolated from the reaction mixture prior to oxidation. The N-substituent on the N-substituted pyridinium salt is preferably an alkyl group or a carbamidoalkyl group.
[GB1308048A]
Patent IE-781506-L (IE)
Title: Thread winding machine
IPC: B65H54/70
Filed: 1978-07-26
Abstract: This winding-apparatus comprises a spindle or collet on which strand or roving is wound and an oscillating mechanism carrying a traverse guide and a follower. The follower is in contact with the circumference and activates an excitation element which continuously acts on a hydraulic or an electric motor which operates the oscillating apparatus. In this way, the oscillating apparatus moves progressively away and by a continuous motion from the spindle as the spool grows. The follower 14 is balanced around an oscillation axis Z-Z to exert a minimal force on the spool. The application disclosed is the winding of strand formed of glass filaments coming from a bushing.
[US4235387A]
Patent IE-871537-L (IE)
Title: Monitoring the displacement of vehicles
IPC: G08G1/123
Filed: 1987-06-10
Abstract: Vehicles are provided with cells (P1, P2) embedded in one of their main outer surfaces, but invisibly and at an indeterminable point. These cells are able to passively define, without individual electrical supply, a remotely readable unique code associated one-to-one with the vehicle. Identifying information in connection with some at least of the unique codes is recorded in at least one reference file (F5). Obligatory transit routes are each provided with a detector (L3) able to read on each vehicle the code defined by the cell(s) which it carries, as well as processing units (04) able to search for whether each code read is to be found in the reference file, and to store the result of this search. <IMAGE>
Patent IE-861575-L (IE)
Title: Emitter coupled logic latch with boolean logic input gating¹network
IPC: H03K19/086
Filed: 1986-06-12
Abstract: A latch circuit including an input logic network that incorporates emitter-coupled logic switching arrangements connected in multiple levels to perform logical operations on the received input signals. The latch circuit is controlled by differential clock signals coupled to a differential switch circuit that is connected to the input logic network to form another switch level. An output buffer is connected to the input logic network to generate output signals of selected logic voltage levels. When the differential clock signals are in a pass condition, the input logic network is enabled to transmit an output signal to the output buffer. When the differential clock signals are in a latch, or hold, condition, the input logic network is disabled and a feedback network is enabled to maintain the signal to the output buffer in the conditions it was in when the differential clock signals changed conditions.
[EP0206891A2]
Patent IE-792052-L (IE)
Title: Paint
IPC: C09D7/00
Filed: 1979-10-25
Abstract: An improved aerosol paint formulation which can be cleaned up with water, comprising a water soluble film forming resin in a solvent system of water soluble solvent and water insoluble solvent. The solvent system contains a relatively large proportion of water insoluble solvent for economy and fire safety.
[US4240940A]
Patent IE-832149-L (IE)
Title: Assembly heat sink for semiconductor devices
IPC: H01L23/40
Filed: 1983-09-14
Abstract: The present invention is directed to an assembly-heat sink for semiconductor fusions. The fusions are disposed within the assembly-heat sink between cylindrical metal members which both cool the fusions and facilitate making electrical contact to the fusions. Top and bottom members of the assembly-heat sink, which entirely enclose the cylindrical members and the fusions are comprised entirely of metal permitting the assembly-heat sink to be cooled from three sides. The fusions are electrically insulated from the top and bottom members of the assembly-heat sink.
[US4518983A]