baber/WOPTO huggingface dataset:
Patent CA-3125275-A1 (CA)
Inventor: MUNRO JEFFREY C
IPC: C08J3/24
Filed: 2019-12-27
Abstract: La présente invention concerne des polyoléfines insaturées et des procédés de préparation associés. La présente invention concerne en outre des formulations durcissables comprenant les polyoléfines insaturées qui présentent une réticulation améliorée.
Patent CA-3125919-A1 (CA)
Title: Electrical apparatus, power supply system and method of manufacturing the electrical apparatus
Inventor: Walton Simon
IPC: H02J3/32
Filed: 2019-11-22
Abstract: Embodiments of the present disclosure provide an electrical apparatus, a power supply system having the same and a method of manufacturing the electrical apparatus. The electrical apparatus comprises a detecting circuit coupled to a generator and configured to detect a frequency of the generator. The electrical apparatus also comprises a controller coupled to the detecting circuit and configured to receive a first signal indicating the detected frequency and adjust the frequency of the generator in response to determining that the detected frequency is out of a predetermined frequency range. In this way, an actively controlling of the changing rate of the power to and from generator may be achieved, if the generator frequency exceeds the configured limits.
Patent CA-3132223-A1 (CA)
Inventor: SHEN YU
IPC: C22C3/00
Filed: 2019-11-13
Abstract: L'invention concerne un procédé de traitement pour alliage de zirconium, comprenant la réalisation d'un traitement d'oxydation et d'élimination de couche de surface sur une couche de surface d'alliage de zirconium. Le traitement d'oxydation et d'élimination de couche de surface comprend : la réalisation d'un traitement d'oxydation sur la couche de surface de l'alliage de zirconium pour obtenir une couche de surface d'oxyde (41), puis l'élimination de la couche de surface d'oxyde (41) pour exposer un substrat métallique (30). La présente invention comprend également un procédé de fabrication d'une couche céramique d'oxyde de surface (10) d'alliage de zirconium et d'un matériau pour un implant médical.
Patent CA-3136722-A1 (CA)
Inventor: HE LINGLING
IPC: C03C10/04
Filed: 2019-04-15
Abstract: A pre-sintered porcelain block for dental restoration; the pre-sintered porcelain block does not contain crystal phases and has a Vickers hardness of 0.5-2 GPa. Due to a low hardness which is significantly lower than that of a porcelain block containing a lithium metasilicate crystal phase, the pre-sintered porcelain block may be processed by using dry machining and can simultaneously be processed by using wet machining when being mechanically processed into a dental restoration shape.
Patent CA-3137579-A1 (CA)
Title: Seal tester apparatus and method
Inventor: CAMPBELL TREVOR
IPC: B07C5/342
Filed: 2020-04-21
Abstract: The invention provides an apparatus and method for testing the integrity of a package, the apparatus comprising a first volume detecting means for detecting a first volume of the package at a first position; conveying means for moving the package from the first position to a second position downstream from the first position; compression means for providing a compression force on the package; a second volume detecting means for detecting a second volume of the package at the second position; determining means for determining the integrity of the package based upon a change in volume of the package; and rejecting means for removing packages, the integrity of which is determined by the determining means not to be intact, wherein the determining means is in electronic signal communication with each volume detecting means independently, wherein the determining means is in electronic signal communication with the rejecting means, wherein the compression means is located above a portion of the conveying means and wherein each volume detecting means independently comprises either two cameras for producing an image of the package or a single time of flight camera.
Patent CA-3137636-A1 (CA)
Title: Apparatus for x-ray irradiation
Inventor: BAKER PETER
IPC: G21K5/10
Filed: 2021-11-04
Abstract: The present invention concerns an apparatus for irradiating goods (1g) with X-rays (11x, 12x), comprising =    A first source (11) of X-rays configured for emitting X-rays along a first irradiation volume (11x) centred on a longitudinal axis (X), =    A conveyor (3h, 3v) configured for driving goods such as to expose a first portion of the goods (1g) through the first irradiation volume, wherein, the conveyor (3v) is configured for driving the target products (1) through the irradiation volume (11x) along the vertical axis (Z).
Patent CA-3138175-A1 (CA)
Inventor: GLENN STEVEN E
IPC: B67D99/00
Filed: 2020-04-26
Abstract: L'invention porte sur un système de conteneurs comprenant un élément de conteneur avec un trou ou une série de trous qui sont scellés par au moins un ensemble de scellés avec au moins un élément de scellé. Lorsque le système de conteneur est placé dans le matériau à capturer, l'élément de scellage de l'ensemble de scellage est déplacé des trous lorsque le matériau exerce une pression vers l'intérieur sur les scellés, ce qui permet au système de conteneurs de s'auto-remplir de matériau. Une fois que la quantité de matériau souhaitée est capturée, le système de conteneurs est retiré et le matériau capturé exerce une pression vers l'extérieur sur l'ensemble du scellement, ce qui fait que l'élément de scellement obture les trous et que le système de conteneur s'auto-scelle.
Patent CA-3138853-A1 (CA)
Inventor: ANDERSON TRAVIS R
IPC: E04H9/02
Filed: 2020-04-21
Abstract: L'invention concerne un mur de contreventement (100) destiné à être utilisé dans des constructions légères ou autres pour transmettre les forces de cisaillement latérales et dissiper l'énergie sur la construction. Dans des exemples, le mur de contreventement (100) comprend un panneau central (102) constitué de bois, et des plaques latérales (104, 106, 108, 110) constituées d'acier. Les plaques latérales peuvent être fixées à des coins inférieurs de première et seconde surfaces (116, 118) opposées du panneau central. Chaque plaque latérale peut comprendre une plaque de fixation pour fixer la plaque latérale au panneau central, et une plaque de retenue qui s'ajuste dans une section de zone réduite du panneau central entre les première et seconde surfaces.
Patent CA-3147310-A1 (CA)
Title: Interior gateway protocol flooding optimization method and device, and storage medium
Inventor: PENG SHAOFU
IPC: H04L45/03
Filed: 2020-06-29
Abstract: The present invention provides an interior gateway protocol flooding optimization method and device, and a storage medium. The interior gateway protocol flooding optimization method comprises: a first node floods a first message carrying link state data and first recording information to a neighbor node, wherein the first recording information comprises indication information of nodes where the link state data passes. In the present embodiment, the indication information of nodes where the link state data passes is carried, so that the nodes are facilitated reducing redundant transmission of link state information according to the indication information, thereby accelerating the convergence rate.
Patent CA-3147783-A1 (CA)
Inventor: BOWEN TYSON D
IPC: C12Q1/6816
Filed: 2020-08-11
Abstract: L'invention concerne des compositions et des méthodes de liaison à une séquence cible d'intérêt. Les compositions trouvent une utilisation dans le clivage ou la modification d'une séquence cible d'intérêt, la visualisation d'une séquence cible d'intérêt, et la modification de l'expression d'une séquence d'intérêt. Les compositions comprennent des polypeptides de nucléase guidée par ARN, des ARN CRISPR, des ARN CRISPR de trans-activation, des ARN guides et des molécules d'acide nucléique codant pour ceux-ci. L'invention concerne également des vecteurs et des cellules hôtes comprenant les molécules d'acide nucléique. L'Invention concerne en outre des systèmes CRISPR pour lier une séquence cible d'intérêt, le système CRISPR comprenant un polypeptide de nucléase à guidage par ARN et un ou plusieurs ARN guides. L'invention concerne également des procédés et des kits pour la détection d'une séquence d'ADN cible.
Patent CA-3147835-A1 (CA)
Title: Chimeric antigen receptors for treating myeloid malignancies
Inventor: DAVILA MARCO
IPC: A61P35/00
Filed: 2020-08-14
Abstract: Disclosed are compositions and methods for treating acute myeloid leukemia (AML) in subjects. In particular, chimeric antigen receptor (CAR) polypeptides are disclosed that can be used with adoptive cell transfer to treat AML. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of trating AML in a subject that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.
Patent CA-3149251-A1 (CA)
Title: Combination washing and drying apparatuses including cooled water condensers
Inventor: KALNITZ HOWARD JAY
IPC: D06F58/20
Filed: 2020-09-11
Abstract: An apparatus (10) includes a closed drying air circuit (18) and a drum (16, 106, 186) in communication with the closed drying air circuit. A condenser (28, 118, 202) is in communication with the closed drying air circuit. The condenser includes a cooled water inlet (60) that directs cooled water into the heated air to remove moisture from the heated air. The condenser includes a condenser water outlet (75) for egress of water from the condenser. The cooled water inlet of the condenser is configured to receive water from a tap water source. A thermoelectric apparatus (36, 126, 210) having a cold side flow device arranged between the cooled water inlet of the condenser and the tap water source is included. The cold side flow device is configured to receive tap water from the tap water source and cool the tap water below a tap outlet temperature using the thermoelectric device (52, 142, 224) before the tap water enters the cooled water inlet of the condenser.
Patent CA-3150550-A1 (CA)
Title: Bispecific antibody car cell immunotherapy
Inventor: CALIGIURI MICHAEL
IPC: A61K35/17
Filed: 2020-09-09
Abstract: Described herein are single vectors that, when expressed in cytolytic immune cells, results in both the expression of (1) a CAR targeting tumor-associated antigens and (2) secretion of a bispecific antibody that on one end recognizes NKG2D expressed on both innate and antigen specific cytolytic immune cells and on the other end targets tumor associated antigens. Unexpectedly, these modifications to the T cells result in enhanced survival and proliferation in vivo. Thus, therapeutic and diagnostic uses are disclosed.
Patent CA-3152031-A1 (CA)
Title: Method for detecting the tendency to form leukemia
Inventor: JUMAA HASSAN
IPC: C12Q1/6886
Filed: 2019-09-10
Abstract: The present invention relates to the field of detection and prophylaxis of a tendency to form the symptoms of a CLL, which is based on a mutation of a specific gene used to form the B-cell receptor (BCR). In order to detect said tendency, an allele of the IGVL3-21 gene, the allele IGVL3-21*01, is detected by sequencing or PCR or a different suitable method.
Patent CA-3153535-A1 (CA)
Inventor: MULLEN RACHEL
IPC: G01N27/447
Filed: 2020-10-09
Abstract: The disclosure relates to methods of characterizing ampholyte compositions suitable for downstream applications such as capillary isoelectric focusing using liquid-chromatography-mass spectrometry.
Patent CA-3153955-A1 (CA)
Title: System with control device and method for vehicle proximity remote
Inventor: TESSIER MARTIN
IPC: B60R25/24
Filed: 2022-03-25
Abstract: A system and method for controlling a transmission of electrical signals (11) by a proximity remote (10) to a receiver (22) for regulating a remote access to premises of a vehicle. The proximity remote (10) is configured to be powered by a battery (19) mounted therein on first and second battery base contacts (24, 25). The system includes: a internal control device (20) insertable within the proximity remote (10) and connectable to the first and second battery base contacts (24, 25); first and second conductors (27) connectable to the control device (20) at respective first and second contacts thereof for controlling a power supplied to the proximity remote (10); and a power supply control device (28) connectable to the first and second connectors (27) for controlling the power supplied to the proximity remote (10), thereby respectively permitting and inhibiting the transmission.
Patent CA-3154073-A1 (CA)
Inventor: NASVESCHUK CHRISTOPHER G
IPC: C07D417/12
Filed: 2020-12-18
Abstract: Il est décrit de nouveaux agents thérapeutiques qui agissent différemment des agents actuellement connus qui entraînent souvent une résistance au traitement. L'invention atteint cet objectif, par exemple, en ciblant les mutants du R-EGF résistants aux médicaments. L'invention concerne en particulier des composés de formule (III) et de formule (IV) qui dégradent le récepteur du facteur de croissance épidermique (R-EGF), comprenant des formes mutantes par l'|| 'intermédiaire de l'ubiquitination de la protéine R-EGF et de la dégradation protéasomique consécutive. Les composés sont également utiles pour le traitement de divers cancers.
Patent CA-3157427-A1 (CA)
Title: Chimeric antigen receptor spacers
Inventor: LAJOIE MARC JOSEPH
IPC: C07K14/725
Filed: 2021-05-12
Abstract: The present disclosure related to chimeric antigen receptors (CARs) comprising immunoglobulin (Ig) derived spacers, e.g., hinge or loop regions, fragments thereof, or combinations thereof. Ig derived spacer confers improved properties to the CARs, e.g., increased cytokine release with respect the CARs with spacers not derived from hinge regions and fragments thereof, loop regions from constant domains and fragments thereof, and combinations thereof. Also provided are cells expressing CARs comprising Ig derived spacers regions and methods to use the CARs to treat diseases or disorders, e.g., cancer. Some of the disclosed Ig derived spacers are fragments from, e.g., IgA1, IgA2, IgD, IgE, IgG1, IgG2, IgG3, IgG4, or IgM. In some aspects, the disclosed Ig derived spacers are derived from non-human immunoglobulins, e.g., mouse immunoglobulins such IgG2A. Other Ig derived spacer disclosed are modular constructs comprising several concatenated Ig hinges or fragments thereof.
Patent CA-3158277-A1 (CA)
Inventor: SMAKMAN ROBERT
IPC: C08F2/20
Filed: 2020-11-20
Abstract: La présente invention concerne un procédé de préparation d'une composition macromoléculaire comprenant des dérivés de phénylglyoxaldéhyde. L'invention concerne également les compositions macromoléculaires per se, et des procédés d'utilisation des compositions macromoléculaires. Les compositions macromoléculaires sont utiles pour subir des réactions ultérieures avec de petites molécules, par exemple pour éliminer de telles petites molécules d'une solution.
Patent CA-3161122-A1 (CA)
Title: Reference optical signal generator
Inventor: AQUE RICHARD
IPC: G01M11/04
Filed: 2020-12-03
Abstract: An optic reference signal generator comprising a housing forming an enclosed space with one or more air flow openings. Within the housing is an optic signal generator driver configured to generate an optic signal generator drive signal. An optic signal generator generates an optic signal responsive to the optic signal generator drive signal. A polarity control unit adjusts polarization of the optic signal to create a polarization adjusted optic signal and a modulator bias generator and controller generates a modulation signal. A pattern signal input receives a pattern signal and a modulator receives the polarization adjusted optic signal, the pattern signal, and the modulation signal to generate a modulated output signal.
Patent CA-3164527-A1 (CA)
Inventor: WILSON NATHAN D
IPC: A47K10/42
Filed: 2020-01-21
Abstract: L'invention concerne des boîtes en carton, en particulier des boîtes en carton destinées à stocker et distribuer un matériau en feuille pliée, et qui sont sensiblement exemptes de matériaux polymères. Les boîtes en carton selon l'invention comportent une fenêtre de distribution constituée de papier, ainsi que des ouvertures de distribution bien adaptées à une distribution par le haut. Les ouvertures de distribution, qui sont de préférence allongées, comportent une pluralité de cuspides et une pluralité de fentes formées sur celles-ci pour agripper et maintenir la feuille pendant la distribution.
Patent CA-3168378-A1 (CA)
Inventor: DEISHER THERESA
IPC: A61K31/573
Filed: 2021-02-26
Abstract: This invention pertains to a novel population of lymphocytes, methods for producing these, and their use in the treatment of diseases.
Patent CA-3168632-A1 (CA)
Inventor: GIRET SIMON
IPC: C07C65/19
Filed: 2021-01-29
Abstract: La présente divulgation concerne un procédé de prévention ou de réduction de la décomposition de la biomasse de cannabaceae pendant le stockage par conditionnement d'une quantité de la biomasse dans un film souple de matériau imperméable aux gaz pour fournir un emballage de biomasse de cannabaceae qui est imperméable aux gaz.
Patent CA-3173566-A1 (CA)
Title: A waterproof container
Inventor: WANG ENLIANG
IPC: B65D43/02
Filed: 2022-09-08
Abstract: A waterproof container is provided, the waterproof container including a base portion, the base portion having a base; an outer wall extending from the base; and an inner wall disposed inwardly from the outer wall, thereby forming a channel between the inner wall and the outer wall; and a lid portion, the lid portion having: a slot within the lid portion; and a seal configured to fit within the slot, the seal including a groove therein, wherein the groove of the seal is configured to accept an end of the inner wall therein when the lid portion is affixed to the base portion.
Patent CA-3177042-A1 (CA)
Title: Panneau prefabrique dote de revetements cimentaires multicouches
Inventor: DOMBOWSKY MICHAEL ANTHONY
IPC: B32B13/02
Filed: 2021-03-26
Abstract: Des exemples de modes de réalisation de la technologie décrite concernent un panneau de construction préfabriqué. Le panneau de construction préfabriqué peut comprendre un noyau isolant ayant des première et seconde faces opposées. Le panneau de construction préfabriqué peut également comprendre une première couche cimentaire accouplée à la première face du noyau isolant. La première couche cimentaire peut comprendre un volume d'une première composition cimentaire. Le panneau de construction préfabriqué peut également comprendre une seconde couche cimentaire accouplée à la première couche cimentaire. La seconde couche cimentaire peut comprendre un volume d'une seconde composition cimentaire. Les première et seconde compositions cimentaires peuvent avoir des propriétés physiques différentes. Les propriétés physiques peuvent être choisies dans le groupe constitué de la densité, de l'ignifugation, de la transmission du son, de la résistance structurale et de la perméabilité à l'humidité.
Patent CA-3177525-A1 (CA)
Title: Methods of generating midbrain dopamine neurons, midbrain neurons and uses thereof
Inventor: STUDER LORENZ
IPC: C12N5/0735
Filed: 2021-04-02
Abstract: The present disclosure provides methods for generating midbrain dopamine neurons and precursors thereof, midbrain dopamine neurons and precursors thereof generated by such methods and compositions comprising such cells, and uses thereof for preventing, modeling, and/or treating a neurological disorder.
Patent CA-3177847-A1 (CA)
Inventor: DAVIE DANIEL
IPC: A41D13/11
Filed: 2022-09-29
Abstract: A surgical apparel system including a surgical helmet to which a garment may mounted.  The surgical helmet includes an electrically powered peripheral device, such as a ventilation assembly, and a headband for removably securing the surgical helmet to the head of a wearer. The headband comprises a rear a portion including opposing ends defining a contact point configured to contact the head of the wearer. The rear portion may also comprise a support member disposed between the opposing ends. The support member may be offset distally from the contact points such that the support member defines a void between the head of the wearer and the headband to allow the hair to collect between the head of the wearer and the support member.
Patent CA-3178182-A1 (CA)
Inventor: WAGER THOMAS
IPC: B25J15/06
Filed: 2016-09-08
Abstract: A system is disclosed for providing high flow vacuum control to an end effector of an articulated arm. The system includes a high flow vacuum source that provides an opening with an area of high flow vacuum at the end effector such that objects may be engaged while permitting substantial flow of air through the opening, and a load detection system for characterizing the load presented by the object.
Patent CA-3180676-A1 (CA)
Title: Reverse water gas shift catalytic reactor systems
Inventor: SCHUETZLE ROBERT
IPC: B01J23/745
Filed: 2021-05-03
Abstract: The present invention describes a processes, systems, and catalysts for the utilization of carbon dioxide into high quality synthesis gas that can then be used to produce fuels (e.g., diesel fuel) and chemicals. In one aspect, the present invention provides a process for the conversion of a feed gas comprising carbon dioxide and hydrogen to a product gas comprising carbon monoxide and water.
Patent CA-3181184-A1 (CA)
Title: Multiplex detection of nucleic acids using mixed reporters
Inventor: TODD ALISON VELYIAN
IPC: C12Q1/6876
Filed: 2020-06-30
Abstract: The present invention provides oligonucleotides and methods for their use in the detection and/or differentiation of target nucleic acids. The oligonucleotides and methods find particular application in amplifying, detecting, and/or discriminating multiple targets simultaneously.
Patent CA-3182152-A1 (CA)
Title: Uses and formulations of cannabinoids
Inventor: NOWAK REINHARD
IPC: A61K9/00
Filed: 2021-05-11
Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from inflammatory conditions associated with autoimmune diseases, chronic inflammatory diseases and inflammatory conditions in connection with infections, including cytokine release syndrome (CRS). Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from conditions as referred to above.
Patent CA-3183076-A1 (CA)
Title: Procede et capteur pour detecter des particules d'aerosol dans l'air ambiant
Inventor: BITTNER ACHIM
Filed: 2021-07-21
Abstract: L'invention concerne, dans un premier aspect, un procédé de détection de particules d'aérosol dans l'air ambiant au moyen d'un capteur de gaz photoacoustique, un volume d'analyse étant présent dans le trajet de faisceau d'un émetteur modulable de sorte que l'émetteur peut utiliser un rayonnement modulable pour stimuler des particules d'aérosol dans le volume d'analyse pour former des ondes de pression sonore qui sont détectables au moyen du capteur. Le volume d'analyse est irradié par le rayonnement modulé au moyen de l'émetteur modulable afin de générer des ondes de pression sonore. Les ondes de pression sonore générées sont mesurées au moyen du capteur, et la présence et/ou la concentration des particules d'aérosol dans l'air ambiant est détectée en se basant sur les résultats de la mesure. Les particules d'aérosol sont de préférence des bioaérosols, de préférence du pollen, des spores, des bactéries et des virus. Dans un autre aspect, l'invention concerne de préférence un capteur de gaz photoacoustique approprié pour la mise en ?uvre du procédé.
Patent CA-3183522-A1 (CA)
Inventor: BEUTNER GREGORY LOUIS
IPC: A61K47/18
Filed: 2021-06-22
Abstract: La présente invention concerne des procédés de synthèse de lipides de formule I utiles dans la synthèse de composés liposolubles pour le ciblage et l'amélioration de l'activité de molécules thérapeutiques, y compris l'ARNsi.