baber/WOPTO huggingface dataset:
Patent NZ-598361-A (NZ)
Title: Compositions comprising tramadol and celecoxib in the treatment of pain
Inventor: VIDELA CES SEBASTIA
IPC: A61K45/06
Filed: 2010-10-15
Abstract: ABSTRACT - 598361 The disclosure relates to a pharmaceutical composition comprising a combination of (rac)-tramadol•HCI and celecoxib or a pharmaceutically acceptable salt or hydrate thereof, wherein the molecular ratio of the (rac)-tramadol•HCI to the celecoxib preferably is a molar ratio of from about 1:1 to about 1:5 or from about 1:1 to about 5:1. Said combination of (rac)-tramadol•HCI and celecoxib is suitable for the treatment of pain selected from acute pain, chronic pain, neuropathic pain, nociceptive pain, mild and severe to moderate pain, hyperalgesia, pain related to central sensitization, allodynia or cancer pain, including diabetic neuropathy or diabetic peripheral neuropathy and osteoarthritis, fibromyalgia; rheumatoid arthritis, ankylosing spondylitis, frozen shoulder or sciatica.
Patent NZ-601788-A (NZ)
Title: Inhibitors of nicotinamide phosphoribosyltransferase and therapeutic uses thereof
Inventor: MCALEXANDER IAN A
IPC: C07D401/12
Filed: 2011-03-01
Abstract: The disclosure relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders. Compounds of the invention include: 3’-[(methylsulfonyl)amino]-N-(4-{ [(pyridin-3-ylmethyl)carbamoyl]amino} phenyl)biphenyl-2-sulfonamide, 1-(4-{ [2-(4-Chloropyridin-3-yl)benzyl]oxy} phenyl)-3-(pyridin-3-ylmethyl)urea, 1-{ 4-[(Biphenyl-2-ylmethyl)(ethyl)amino]phenyl} -3-(pyridin-3-ylmethyl)urea and 3’-[(4-Methylpiperazin-1-yl)methyl]-N-(4-{ [(pyridin-3-ylmethyl)carbamoyl]amino} phenyl)biphenyl-2-sulfonamide.
Patent NZ-607031-A (NZ)
Title: Arylosulfonamides for the treatment of cns diseases
Inventor: KOŁACZKOWSKI MARCIN
IPC: C07D413/12
Filed: 2011-09-16
Abstract: Disclosed are dihydropyridine arylsulphonamide derivatives of formula (I) where the substituents are as defined herein and pharmaceutically acceptable salts thereof, an example of which is N-{ 4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]butyl} naphthalene-1-sulphonamide. The compounds may be useful for the treatment and/or prevention of disorders of the central nervous system including schizophrenia, bipolar disorder, depression, sleep disorders and addiction as well as other neurological conditions.
Patent NZ-612775-A (NZ)
Title: System and a method for controlling an automatic milking system
Inventor: EINEREN ELLINOR
IPC: A01J5/013
Filed: 2011-12-13
Abstract: A system (1) for controlling an automatic milking system (2), configured for automatically receiving, identifying and selectively milking a lactating animal in accordance with a set of milking parameters associated with said animal. The system comprises a thermal imaging device (3), configured for generating at least one current thermal image of at least a portion of an udder of said animal, a storage device (4), configured for storing at least one reference thermal image of said udder, and a processing device (7), configured for comparing at least one current value derived from said at least one current thermal image and/or at least one current thermal image with at least one reference value derived from said at least one reference thermal image and/or at least one reference thermal image. The processing device is arranged to selectively provide a status indication of said animal in response to a result of said comparison. The automatic milking system may automatically adjust the milking parameters associated with an animal in response to a status indication provided.
Patent NZ-623147-A (NZ)
Title: Genetically modified t cell receptor mice
Inventor: MACDONALD LYNN
IPC: C07K14/705
Filed: 2012-10-26
Abstract: Disclosed is a genetically modified non-human animal, comprising in its genome: -an unrearranged T cell receptor (TCR) α variable gene locus comprising at least one human Vα segment and at least one human Jα segment, wherein the TCRα variable gene locus is operably linked to a non-human TCRα constant gene sequence, wherein the unrearranged TCRα variable gene locus replaces an endogenous non-human TCRα variable gene locus, and/or -an unrearranged TCRβ variable gene locus comprising at least one human Vβ segment, at least one human Dβ segment, and at least one human Jβ segment, wherein the unrearranged TCRβ variable gene locus is operably linked to a non-human TCRβ constant gene sequence, wherein the unrearranged TCRβ variable gene locus replaces an endogenous non-human TCRβ variable gene locus.
Patent NZ-623595-A (NZ)
Title: Auction method and auction server
Inventor: LEE JEONG-GAB
IPC: G06Q30/08
Filed: 2012-03-13
Abstract: Disclosed is an auction server for conducting auctions over a network. The auction server includes a storage configured to maintain a database of a highest price of a specific product, a lowest price of the specific product, and a limited number of successful bidding products. A receiver (120) receives bidding information including bidding prices for the specific product between the lowest price and the highest price from terminals of bidders wherein the terminals of bidders are connected to the network. A selector (130) selects successful bidders in consideration of the limited number of successful bidding products and the bidding information from among the bidders and a lowest successful bidder from among the selected successful bidders. The lowest successful bidder is the successful bidder who has made a successful bid at the lowest bidding price wherein bidding is terminated when a predetermined bidding time is elapsed. A payment requester (140) applies the bidding price of the lowest successful bidder as a final sale price to all of the successful bidders and the terminals of the successful bidders are connected to the network. A settlement unit (150) settles an auction commission for the seller on the basis of an amount calculated by subtracting the lowest price from the bidding price of the lowest successful bidder. A controller (160) controls the storage, the receiver (120), the selector (130), the payment requester (140) and the settlement unit (150) by controlling bidding prices out of the range between the highest price of the specific product and lowest price of the specific product not to be input.
Patent NZ-626187-A (NZ)
Title: Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
Inventor: BRAHMBHATT HIMANSHU
IPC: A61P35/00
Filed: 2012-12-12
Abstract: Disclosed is the use of a composition in the manufacture of a medicament for treating a brain tumour, wherein the composition comprises a plurality of intact, bacterially derived minicells, and wherein: (A) each minicell of the plurality (i) comprises an antibody that specifically recognizes a tumour cell antigen and (ii) encompasses an anti-neoplastic agent; and (B) the brain tumour has blood vessels with fenestrations in its walls through which the minicells can extravasate passively.
Patent NZ-626612-A (NZ)
Title: Fire-proof illuminating web, fire-proof illuminating structure, their manufacturing processes and their use
Inventor: DIDIER BENOÎT
IPC: G02B6/04
Filed: 2012-12-17
Abstract: The disclosure relates to an illuminating web characterised in that it is fire-proofed by a fire-proofing composition impregnated into the bulk of the illuminating web and/or contained in a coating on at least one side of the illuminating web. The illuminating web has an improved performance in terms of fire safety. It is better suited to the fire safety standards currently in force. It also has an advantageous illumination performance and possesses good acoustic properties when it is integrated into a support designed to provide sound insulation. The invention also relates to an illuminating structure formed by assembling said web with a rigid or semi-rigid supporting carrier. This structure may especially be used as a partition wall or ceiling in a building. As for the web itself, it may be used as a canvas to be painted or as a wall cloth or form part of one of these.
Patent NZ-628361-A (NZ)
Title: A support unit for use in a mattress or cushion
Inventor: PAUL LONGMAN
IPC: A47C27/00
Filed: 2013-06-13
Abstract: A support unit (100) for use in a mattress or cushion is disclosed. The support unit comprises an array of upright primary coil springs (110) arranged in a series of aligned rows (111) and columns (112) so as to define voids (117) between sets of four adjacent primary coil springs (110). Secondary support elements (120) are located in at least several of the voids (117). Then elements could be springs or foam columns. The support unit may be divided into zones characterised by different density or patterning’s of the secondary support elements. The lower ends of the primary coil springs and secondary support elements all lie substantially in a common plane, such that the upper ends of the secondary support elements lie in a plane below the plane of the upper ends of the primary coil springs. This results in the secondary support elements having no support effect until a load sufficient to compress the primary coil spring by an amount equal to the difference in heights between the primary coil springs and the secondary support elements is achieved. The additional support provided by the secondary support elements is thus only effectively achieved when the support unit is subjected to a heavy local load, either as a result of a heavier body mass of the person lying on the mattress or localised increased load resulting, for example, from a person sitting or standing in a localised area of the support unit.
Patent NZ-704269-A (NZ)
Title: Rspo3 binding agents and uses thereof
Inventor: GURNEY AUSTIN L
IPC: A61K39/395
Filed: 2013-07-12
Abstract: The present invention relates to RSPO-binding agents, particularly RSPO3-binding agents and methods of using the agents for treating diseases such as cancer. The present invention provides antibodies that specifically bind human RSPO3 proteins and modulate β-catenin activity. The present invention further provides methods of using agents that modulate the activity of RSPO3 proteins and inhibit tumor growth. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an agent or antibody of the present invention to a patient having a tumor or cancer.
Patent NZ-707859-A (NZ)
Title: Inhibitors of sodium glucose cotransporter 1
Inventor: CARSON KENNETH GORDON
IPC: C07D309/10
Filed: 2013-11-18
Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula (I): the various substituents of which are defined herein.
Patent NZ-713828-A (NZ)
Title: Crystalline forms of a bruton’s tyrosine kinase inhibitor
Inventor: PURRO NORBERT
IPC: A61P35/00
Filed: 2013-06-03
Abstract: Described herein is the Bruton’s tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1 H-pyrazolo [3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions that include the Btk inhibitor and methods of using the Btk inhibitor in the treatment of diseases or conditions that would benefit from inhibition of Btk activity.
Patent NZ-714044-A (NZ)
Title: Cd19 specific chimeric antigen receptor and uses thereof
Inventor: GALETTO ROMAN
IPC: C12N15/63
Filed: 2014-05-12
Abstract: The present invention relates to chimeric antigen receptors (CAR). CARs are able to redirect immune cell specificity and reactivity toward a selected target exploiting the ligand-binding domain properties. In particular, the present invention relates to a Chimeric Antigen Receptor in which extracellular ligand binding is a scFV derived from a CD19 monoclonal antibody, preferably 4G7. The present invention also relates to polynucleotides, vectors encoding said CAR and isolated cells expressing said CAR at their surface. The present invention also relates to methods for engineering immune cells expressing 4G7-CAR at their surface which confers a prolonged “activated” state on the transduced cell. The present invention is particularly useful for the treatment of B-cells lymphomas and leukemia.
Patent NZ-733081-A (NZ)
Title: A float
Inventor: TROLLIP CHRISTOPHER JOHN
IPC: F16K31/26
Filed: 2017-06-14
Abstract: The present invention relates to a float used in tanks and reservoirs to control a float valve. Instead of conventional floats which have one fixed orientation, the float of the present invention has a structure which enables it to be positioned in two different orientations. The float of the present invention may be used in tanks or reservoirs where two different minimum water levels are possible.
Patent NZ-739206-A (NZ)
Title: Composition containing n-(n-butyl) thiophosphoric triamide adducts and reaction products
Inventor: OWUSU-ADOM KWAME
IPC: C05G3/90
Filed: 2016-07-22
Abstract: Reaction products and methods for making and using such reaction products are provided. For example, a reaction product comprising an adduct formed from urea, formaldehyde, and a urease inhibitor, such as N-(n-butyl)thiophosphoric triamide (NBPT) is described, which can be provided in various forms. For example, such a reaction product can be in the form of a solid or solution. Such a reaction product can also be combined with one or more additional components, including but not limited to, additional urease inhibitor and/or a nitrogen-based fertilizer composition.
Patent NZ-752145-A (NZ)
Title: Node for a radio communication network and operating method
Inventor: SIOMINA IANA
IPC: H04L1/18
Filed: 2017-09-29
Abstract: Methods and systems for a 3GPP radio communication network for selecting a relative timing from among a plurality of predetermined relative timing choices for sending a second transmission from a wireless device in response to receiving a first transmission from a network node. Whereby the network node being arranged for sending of the first transmission and subsequent receiving of the second transmission in response to said first transmission, wherein said network node is furthermore arranged to perform a selecting process for selecting a relative timing for sending of said second transmission from among a plurality of predetermined relative timing choices, and to send to the wireless device Radio Resource Control, RRC, and Downlink Control Information, DCI, control message signaling, wherein said RRC and DCI control message signaling comprises an RRC control message for configuring a set of possible relative timing selections and a DCI control message for selecting from the configured set. The wireless device being arranged for reception of the first transmission and subsequent sending of the second transmission in response to said first transmission, wherein said wireless device is furthermore arranged to receive from the network node Radio Resource Control, RRC, and Downlink Control Information, DCI, control message signaling, wherein said RRC and DCI control message signaling comprises the RRC control message for configuring the set of possible relative timing selections and the DCI control message for selecting from the configured set, and to perform a selecting process for selecting a relative timing for sending said second transmission from among a plurality of predetermined relative timing choices, wherein the selecting said relative timing for sending said second transmission is done according to the received DCI control message.
Patent NZ-766985-A (NZ)
Title: Patient interface
Inventor: EVES MATTHEW
IPC: A61M16/06
Filed: 2019-03-28
Abstract: A patient interface comprising: a plenum chamber for a patient interface, the plenum chamber being pressurisable to a therapeutic pressure of at least 6 cmH2O above ambient air pressure throughout a patient’s respiratory cycle in use, the plenum chamber comprising: one or more walls at least partially enclosing a volume of space; a seal-forming structure constructed and arranged to form a seal with a region of the patient’s face surrounding an entrance to the patient’s airways, the seal-forming structure comprising a nasal portion having at least one nasal hole configured to deliver a flow of air at said therapeutic pressure to an entrance to the patient’s nares in use, the seal-forming structure comprising an oral portion having an oral hole configured to deliver the flow of air at said therapeutic pressure to an entrance to the patient’s mouth in use, the seal-forming structure constructed and arranged to maintain said therapeutic pressure in the plenum chamber throughout the patient’s respiratory cycle in use; and one or more plenum chamber inlet ports sized and structured to receive the flow of air at the therapeutic pressure for breathing by the patient throughout the patient’s respiratory cycle in use a positioning and stabilising structure configured to generate a force to hold the seal-forming structure in a therapeutically effective position on the patient’s head, wherein the seal-forming structure comprises a central portion configured to seal against an inferior periphery of the patient’s nose in use, and wherein the seal-forming structure comprises intermediate portions configured to contact the ala of the patient’s nose in use, the intermediate portions having a greater stiffness than the central portion; wherein the nasal portion comprises a pair of posterior corners each configured to contact the patient’s face in an area lateral and inferior to a respective one of the ala of the patient’s nose in use, the posterior corners having a greater thickness than the intermediate portions.
Patent PT-103070-A (PT)
Inventor: ELMO EMANUELA
IPC: B60B1/00
Filed: 2004-02-10
Abstract: A bicycle wheel (1) comprising a rim (2), an axle hub (3) with a pair of flanges (4, 5) at the opposite ends, a first set of radial elements (6) extending between the said rim (2) and one of the flanges (4), and a second set of radial elements (7) extending between the said rim (2) and the other flange (5), these radial elements (6, 7) being constituted by at least one pair of non-secant spokes (8, 9, 12, 13) arranged in such a way as to form pairs of radial elements, in which a radial element of the first set (6) corresponds to a radial element of the second set (7) extending in the lame radial direction as the radial element of the first set (6), characterised in that for a pair of corresponding radial elements (6, 7), the radial element (8, 9) of the said first set is attached to the rim by means of joining points (11) situated between those (15) of the radial element (12, 13) of the second set.
Patent RU-94010185-A (RU)
Inventor: CHASOVSKOJ A A
IPC: G01S3/14
Filed: 1994-03-22
Abstract: FIELD: radiolocation. SUBSTANCE: radar has two-beam indicator, unit of two fibre-optical rules, unit of two photoelectric multipliers, subtracter- adder, unit of two selectors and coincidence element. In this case first and second outputs of two-channel receiver are connected to first and second inputs of two-beam indicator which has two optical couplings to unit of two fibre- optical rules by input which are optically conjugate by output to unit of two photoelectric multipliers which first and second outputs are connected to first and second inputs of unit of two selectors. Its output is linked to first and second inputs of coincidence element. Output of the latter is coupled to first input of plan-position indicator. First and second inputs of subtracter are also connected to first and second outputs of unit of two photoelectric multipliers. Output of subtracter is linked to first input of adder with output connected to input of receiving selsyn and input connected to transmitting selsyn. EFFECT: increased precision of determination of azimuth.
Patent RU-94010886-A (RU)
Inventor: GOLUB V I
IPC: A61B17/36
Filed: 1994-03-28
Abstract: FIELD: medical engineering; surgical instruments. SUBSTANCE: proposed apparatus comprises continuously cooled cryoapplicator 10 made in form of two cavities arranged symmetrically in relation to heater of electric knife 1. Cavities are made of thin-walled pipes having O-shaped cross-section. Pipes are fixed on common base in one and same plane so as to form integrated assembly capable of performing oscillatory movements. Electric knife 1 is subjected to additional blowing with gaseous coolant, while automatic monitoring and adjustment of temperature of electric knife heaters ensure stability of its thermal conditions as electric knife stays in air and as it is plunged into body tissues in course of surgical operations. Apparatus makes it possible to automatically maintain desired cooling/heating conditions for tissues to achieve cold-induced analgesia of tissues, followed by painlessly disconnecting them. EFFECT: higher speed of tissue disconnecting operation; lower traumatism rate for tissues in disconnection zone; greater reliability of apparatus in operation.
Patent RU-94016154-A (RU)
Inventor: SALFETNIKOV M A
IPC: G01R29/16
Filed: 1994-05-04
Abstract: FIELD: digital measuring equipment; can be used for measurement of coefficients of zero and negative phase-sequences of three-phase circuit. SUBSTANCE: the device for measurement of components of positive and negative phase- sequences of voltages of three-phase generators uses two analog-to-digital converters, voltage divider consisting of two similar resistors, angle encoder, interface unit and a microcomputer. Introduction of an additional analog-to-digital converter, elimination of the voltage divider provides for measurement of asymmetry coefficients of zero and negative phase-sequences; the interface unit has three input-output ports, local line, data bus buffer and a control system. EFFECT: improved design.
Patent RU-94025949-A (RU)
Inventor: VOZNESENSKIJ V A
IPC: B66C15/00
Filed: 1994-07-12
Abstract: FIELD: safety devices for load handling facilities. SUBSTANCE: single lifting capacity limiter is used for two lifting mechanisms of crane. Limiter has weighing unit 1 to which connected through pivot 17 is compensating lever 18 and mounted on it are stop-hinges 19 and 20 given possibility of contact with crane bogie frame 14 and compensating pulleys 21 and 22. Stop hinges 19 and 20 pulleys 21 and 22 are secured to compensating lever 18 at distances determined by relation given in description. EFFECT: simplified design of crane and reduced amount of metal used due to smaller dimensions of crane bogie. 1 dwg
Patent RU-94028266-A (RU)
Inventor: ALEN KORB E
IPC: C07D235/24
Filed: 1994-08-04
Abstract: FIELD: pharmaceutical industry. SUBSTANCE: products of formula I:wherein Xis alkyl, alkenyl, alkynyl, alkoxy or alkylthio, nis integer of 0 to 4; A, A, Aand Aare (CH)-, -CH=, -N= -NH-, >C=R,, -S- and -0- in which n is integer of 0 to 2; Ris oxygen atom, alkenyl or N=O-R, in which Ris hydrogen, carboxy, acyl, amino, alkyl, alkenyl, alkoxy, alkylthio, phenyl, benxyl, phenoxy; Xis cyano, carboxy, -(CH)-SO-Z-R, in which nis integer of 0 or 1; Z is -NH- , NH-CO-, NH-CO-O-, N= CH-N-R, NH-CO-NH or single bond, and Rand Rare hydrogen, alkyl, alkenyl, cycle and also salts thereof, the preparation and use thereof as medicaments. EFFECT: improved properties of the title compounds.