baber/WOPTO huggingface dataset:
Patent JP-2002174598-A (JP)
Title: Apparatus and method for examining surface
Inventor: TAKEI TOSHIJI
IPC: G01N21/84
Filed: 2000-12-07
Abstract: PROBLEM TO BE SOLVED: To provide an apparatus and a method for examining a surface, capable of efficiently examining or investigating the surface of an object to be examined, in which a specular reflecting region and a random reflecting region exist in parallel. SOLUTION: The apparatus 11 for examining the surface of the object 1 to be examined, in which the specular reflecting region 3 and the random reflecting region 2 exist in parallel comprises a polarization illumination optical system 21 for irradiating polarization on the object 1, a branching means 34 for branching the light reflected by the object 1 into two lights of perpendicular polarization site, an imaging optical system 41 for detecting the two lights for imaging the images of the object 1, imaging elements 61 and 62 for forming two focused images, and an image processing unit 71 for identifying the boundary between the region 3 and the region 2. In this case, one of the two polarization sites is set substantially coincident with the polarization site of the forwardly reflected polarized light.
Patent JP-2002172254-A (JP)
Title: Shutter structure for pachinko ball counting device
Inventor: ENOMOTO HIROSHI
IPC: G06M7/00
Filed: 2000-12-07
Abstract: PROBLEM TO BE SOLVED: To provide a shutter for a Pachinko ball counting device capable of being fitted to an existing Pachinko ball counting device for reliably preventing a fraudulent action by a player and a worker of a game hall. SOLUTION: A discharge hole 2 of Pachinko balls is provided on the bottom face of a box-shaped shutter body 1, and a shutter plate 4 is provided on the upper face of the shutter body 1. A mechanism driven by a motor 10 to horizontally move the shutter plate 4 is provided on the shutter plate 4, and a device limiting the force transmitted on the transmission path of the power of the motor 10 is provided.
Patent JP-2002180865-A (JP)
Title: Exhaust emission control device for internal combustion engine
Inventor: IRISAWA YASUYUKI
IPC: B01D53/81
Filed: 2000-12-08
Abstract: PROBLEM TO BE SOLVED: To properly release NOX from a NOX absorbent. SOLUTION: The NOX absorbent for absorbing NOX in the case of a lean air/fuel ratio is arranged in an engine exhaust passage and a NOX ammonia sensor 29 is arranged it the engine exhaust passage in the downstream of the NOX absorbent 23. An extra amount of reducing agent for the release of NOX is found from a change in concentration of ammonia detected by the NOX ammonia sensor 29 when a rich air/fuel ratio is established for the release of NOX from the NOX absorbent 23.
Patent JP-2002177779-A (JP)
Title: LEAN NOx CATALYST OR DIESEL ENGINE
Inventor: TAKAGI NOBUYUKI
IPC: F01N3/28
Filed: 2000-12-11
Abstract: PROBLEM TO BE SOLVED: To provide a lean NOx catalyst for Diesel engine, which is particularly suitable for the Diesel engine. SOLUTION: The lean NOx catalyst is for purifying NOx contained in the exhaust gas from the Diesel engine using a noble metal catalyst and a NOx adsorbing material and the NOx absorbing material is supported with a ratio of 0.05-2.0 mol per 1 L volume of a support (zeolite or the like). The NOx absorbing material contains at least lithium and potassium and the ratio (Li/K) by mol of lithium to potassium is >=1.4. The absorbing material contains further barium and the ratio (Li/Ba) by mol of lithium to barium is preferably >=1. The catalyst has excellent NOx absorption performance and sulfur poisoning recovery performance in the operation temperature range of the lean NOx catalyst for Diesel engine.
Patent JP-2002177165-A (JP)
Title: Hand drier
Inventor: KUMAMOTO YASUHIRO
IPC: A47K10/48
Filed: 2000-12-13
Abstract: PROBLEM TO BE SOLVED: To provide a hand drier by which power consumption in a waiting state which occupies most of the time of operation time is reduced. SOLUTION: The hand drier is provided with a hand insertion part 6 for inserting hands, an air blow-out port 2 for blowing out air to the inserted hands, a hand detection means 4 for detecting the hands inserted to the part 6 and a gas supplying means 6 for supplying the gas to the port 2 based on a detection signal from this means 4 and has a power consumption reduction means 11 for reducing power consumption in the case of waiting for the operation of the drier A.
Patent JP-2002180581-A (JP)
Title: Mounting structure for external wall panel
Inventor: MATSUMOTO SUSUMU
IPC: E04B2/94
Filed: 2000-12-14
Abstract: PROBLEM TO BE SOLVED: To provide a mounting structure for an external wall panel, which can prevent separation of tiles bonded to an external wall surface and damage of the external wall panel surface, is easy to mount, and inexpensive in cost. SOLUTION: The mounting structure for the external wall panel is formed of a support 13, a bolt 6, a fixture 11, and a self support fitting 12. The support 13 is fixed to an upper end of the external wall panel 1, and consists of two plate portions. The bolt 6 connects both the plate portions together. The fixture 11 is fixed to a building skeleton 2 and has a horizontal long hole formed in an end thereof. The self support fitting 12 is fixed to the building skeleton 2 and bears a part of a lower bed header of the external wall panel 1. The bolt 6 penetrates through the long hole of the fixture 11. Further, it is preferable that the support 13 is formed of a plate member having a U-shaped cross section, and that a gap is maintained between the plate portions when the bolt 6 is fastened.
Patent JP-2002180174-A (JP)
Title: Mg-TYPE HYDROGEN STORAGE ALLOY HAVING HIGH STORAGE CAPACITY
Inventor: OSAWA MASAHITO
IPC: C22C23/00
Filed: 2000-12-14
Abstract: PROBLEM TO BE SOLVED: To provide a hydrogen storage alloy having high storage capacity and high reactivity and capable of occluding and releasing large amounts of hydrogen in a short time. SOLUTION: The Mg-type hydrogen storage alloy with high hydrogen storage capacity has >3.6 mass% hydrogen storage capacity and also has a composition represented by the general formula: Mg1-x-yNixMy (wherein, 0.01<=x<=0.32, 0.01<=y<=0.32 and 0.02<=x+y<=0.33 are satisfied; and M is one or more elements selected from Li, Al, Si, Ca, Ti, Y and Zr).
Patent JP-2001170975-A (JP)
Title: Method for injection-molding rubber
Inventor: SHIN-SHAN CHAN
IPC: B29C45/27
Filed: 2000-12-15
Abstract: PROBLEM TO BE SOLVED: To provide a gate system which improves the uniformity of mixing and temperature of rubber and the degree of orientation of fibers contained in the rubber discharged from the gate system. SOLUTION: In a method for injection-molding rubber, the gate system 24 leads the rubber by way of the first section 26 to make the rubber flow across the flow direction of the rubber 22 passing in the system 24. Next, the rubber is led to an adjacent section 28 to flow through the system 24 in the flow direction of the rubber passing through the system 24 and passes through the section 28. The system 24 forms the uniform flow of the highly mixed rubber, when rubber filled with fibers is injection-molded, the fibers are oriented in a specified direction to form a desired flow pattern.
Patent JP-2002188458-A (JP)
Title: Repairing method and repair equipment for gas turbine parts, and gas turbine parts and gas turbine system for power generation using the repair method
Inventor: HAMADA TAKAHIRO
IPC: F01D5/28
Filed: 2000-12-18
Abstract: PROBLEM TO BE SOLVED: To provide a repairing method of a gas turbine part, capable of improving the life time of a base material by filling cracks generated in a ceramic layer. SOLUTION: For repairing the cracks generated in the ceramic layer 3 in the repair method of the gas turbine part 4 having a coating layer composed mainly of ceramic, the parts are subjected to heat-treatment and the ceramic layer 3 is sintered, thereby repairing the crack 15.
Patent JP-2002183153-A (JP)
Title: Device and method for providing physiological- phenomenon-related gene information and recording medium stored with program for providing the same
Inventor: KITO MASA
IPC: G06Q50/10
Filed: 2000-12-18
Abstract: PROBLEM TO BE SOLVED: To provide related gene information by computing the development frequency of a gene provided by a user according to genome databases wherein specific gene groups are classified. SOLUTION: This physiological-phenomenon-related gene providing device 20 which provides a physiological-phenomenon-related gene including the development frequency of the gene for gene information from the user includes a user data management unit 30 which receives the gene information from the user, a physiological-phenomenon-related genome database having genome databases 51, 52, and 53 which consist of physiological-phenomenon-related gene groups and have the respective physiological-phenomenon-related gene groups in advance, and an arithmetic unit 40 which compares the gene information provided by the user and counts genes included in gene information matching genes belonging to the classified genome databases to compute the development frequency of the genes.  Further, the device has an output means which outputs the physiological-phenomenon-related genes including the manifestation frequency of the genes.
Patent JP-2002179887-A (JP)
Title: Halogen-free flame-retardant epoxy resin composition and prepreg, laminate, copper-clad laminate and printed wiring board comprising the same
Inventor: SUZUKI TETSUAKI
IPC: H05K1/03
Filed: 2000-12-19
Abstract: PROBLEM TO BE SOLVED: To obtain an epoxy resin composition capable of exhibiting excellent flame retardance without containing a halogen and providing a glass-epoxy copper-clad laminated product having excellent heat and moisture resistances responsive to a leadless solder and small-diameter drilling properties. SOLUTION: This halogen-free flame-retardant epoxy resin composition is characterized in that the composition consists essentially of (A) a phenoxyphosphazene compound or a condensation phosphoric ester compound, (B) a phosphorus-containing polyeoxide compound containing a phosphorus- containing compound such as 10-(2,5-dihydroxyphenyl)-10-hydro-9-oxa-10- phosphaphenanthrene-10-oxide, (C) a nitrogen-containing curing agent for an epoxy resin and (D) an inorganic filler. The prepreg and laminated product are impregnated with the epoxy resin composition.
Patent JP-2002180112-A (JP)
Title: Method for manufacturing high melting point metal powder material
Inventor: KAN TAKESHI
IPC: B22F9/30
Filed: 2000-12-19
Abstract: PROBLEM TO BE SOLVED: To provide a method for manufacturing a high melting point metal powder material having high purity and spherical shape and also having a particle size regulated to values within the range where handling of powder can be facilitated. SOLUTION: Powder of high melting point-metal oxide or high melting point- metal compound is used as a raw material and fed into the high-temperature region of RF high-temperature plasma where hydrogen is introduced, and the powder is subjected to drop feed refining in the high-temperature region. By this method, the high-purity spherical powder having excellent handling property can be manufactured.
Patent JP-2002187315-A (JP)
Title: Printer and printing method
Inventor: ORII SATORU
IPC: G06F3/12
Filed: 2000-12-21
Abstract: PROBLEM TO BE SOLVED: To provide a printer capable of printing at a high speed. SOLUTION: This printer 1 can receive and interpret a second kind printing command with a printing image sent in a form of JPEG data as well as a first kind printing command with a printing image sent in a form of CMYK binary data from a host apparatus 2. In the case of receiving the second kind printing command, prior thereto, a predetermined transition command is received. A command controller 4 judges either a second kind printing command or a first kind printing command is expected by detecting the transition command.  In order to prevent a command processing error by mistaking the same command as the transition command included in the CMYK binary data as the transition command, the command controller 4 checks whether or not an engine controller 5 is processing binary data in the case the transition command is detected, and judges that it is a mistake in the case of execution of the process.
Patent JP-2002190238-A (JP)
Title: Structure of cursor key button
Inventor: YAMADA HIROYASU
IPC: H01H25/06
Filed: 2000-12-21
Abstract: PROBLEM TO BE SOLVED: To provide a structure of a cursor key button where a multiple switches can be selected in a small area. SOLUTION: In the structure of a cursor key button 10, a cursor key button 1 provided with a discotic cursor key button body 2 which is incorporated in a portable device to be freely rotated but able to be fixed at a proscribed position and a direction key button part 3 constituted so as to be able to oscillate with a position that is eccentric from the center of rotation of the cursor key button body 2 as the center and switches 6a to 6h that are pushed down by having the direction key button 3 oscillated at a prescribed position where the cursor key button 1 is fixed.
Patent JP-2002194225-A (JP)
Title: Foamable fireproof composition
Inventor: NAKAJIMA TORU
IPC: C08L101/00
Filed: 2000-12-22
Abstract: PROBLEM TO BE SOLVED: To provide a foamable fireproof composition which expands and foams by heating and/or a fire to form a carbonized layer of high heat insulating properties to thereby exhibit an effect of fireproofing a combustible material or preventing a smoke, a flame, a gas generating by combustion, and the like from flowing out, with the effect free from a decrease due to water or moisture, i.e., exhibiting high water and moisture resistances, and which is excellent in formability into a sheet. SOLUTION: The composition contains (A) a thermoplastic resin, (B) a lubricant, (C) a phosphorus compound, and (D) a polyfunctional alcohol.
Patent JP-2002155299-A (JP)
Title: Soap composition
Inventor: SHIMIZU KAZUO
IPC: C11D10/06
Filed: 2000-11-17
Abstract: PROBLEM TO BE SOLVED: To provide a soap composition having excellent deodorant properties and stamina while improving detergency, foaming properties and soap characteristics (foamability, water-solubility, dripping properties and skin feeling) per weight by composing a double salt shape of three kinds of fatty acids, using the double salt shape as a base, devising a crystal structure in a framing method as a method for sufficiently utilizing the characteristics of a tourmaline ore. SOLUTION: This soap composition is obtained by formulating the mixed acids of three kinds of myristic acid, palmitic acid and stearic acid, and Na and K in a specific ratio, with a polyhydric alcohol, sucrose and the tourmaline ore, regulating volatile components so as to be <30% to provide a framing type soap composition, and subjecting the resultant soap composition to an aging processing. Optionally, a monoterpene- or a sesquiterpene-based hydrocarbon is included therein. As a result, the mild soap having the stamina (durability), preferable feeling of little disintegration in water, high familiarity to the hand skin and water, and substance is provided. The soap with the deodorant properties and aroma, having an excellent finish is obtained without adding an excessive chemical or antimicrobial component.
Patent JP-2002198713-A (JP)
Title: Composite directional coupling circuit and layered directional coupler employing the circuit
Inventor: KITA MASAMI
IPC: H01P5/18
Filed: 2000-12-25
Abstract: PROBLEM TO BE SOLVED: To provide small directional coupler with respect to a composite directional coupling circuit applied to a communication device or the like and with respect to a layered directional coupler employing the circuit. SOLUTION: This invention provides a composite directional coupling circuit consisting of a combination of a low-pass filter circuit 1 and a directional coupling circuit 3, where a series line of two 3rd, 4th transmission lines 6a, 6b forms a 1st transmission line 2 being a component of the low-pass filter circuit 1 and a 2nd transmission line 4 forming a sub line of the directional coupling circuit 3 is coupled with only the 3rd transmission line 6a.
Patent JP-2002199285-A (JP)
Title: Image acquisition device and method
Inventor: INOUE HITOSHI
IPC: H04N5/367
Filed: 2000-12-26
Abstract: PROBLEM TO BE SOLVED: To provide an image acquisition device and method with high reliabil ity that corrects pixel information of a defective pixel without giving a sense of incongruity to a viewer in cases where the pixel information is corrected correspondingly to the defective pixel when the defective pixel exists so as to acquire an image with high definition. SOLUTION: The image acquisition device is provided with a correction processing means 14 that corrects acquired pixel information corresponding to a position of a defective pixel in the case that a functional defect exists in a prescribed pixel and provides an output. The means 14 corrects a correction value obtained by an arithmetic operation using a non-defective pixel existing around the defective pixel so that the correction value has pseudo fluctuations equivalent to light fluctuations or fluctuations in a signal of an image receiver.
Patent JP-2002193059-A (JP)
Title: Air bag system
Inventor: ABE KAZUHIRO
IPC: B60R21/20
Filed: 2000-12-28
Abstract: PROBLEM TO BE SOLVED: To make swelling of an air bag performable in a regular direction, by bursting a large/small expansion doors opened by the same timing. SOLUTION: A tear line comprises a lateral directional tear line 13 in a direction traversing a module cover 12A and longitudinal directional tear lines 14, 15 continued to both ends of the lateral directional tear line 13 to extend in an upper/lower longitudinal direction, a region surrounded by these lateral directional tear line 13 and longitudinal directional tear lines 14, 15 is made to serve as a small/large expansion door 17, 18, and thin thickness is formed in the longitudinal directional tear lines 14, 15 in a side of the large expansion door as compared with in the longitudinal directional tear lines 14, 15 in a side of the small expansion door 17.
Patent JP-2002205745-A (JP)
Title: Carrying bag
Inventor: OKI SHINJI
IPC: B65D85/57
Filed: 2000-12-28
Abstract: PROBLEM TO BE SOLVED: To prevent accommodated stuff from dropping out by a simple configuration. SOLUTION: A drop-out preventive part 4 is formed by inserting an opening part of a face side member 1a of a carrying bag 1 having the face side member 1a and a back side member 1b which are rectangular and formed of an elastic material between the accommodated stuff (an electronic recording medium) 10 and the back side member 1b, and the accommodated stuff (the electronic recording medium) 10 is prevented from being dropped out.
Patent JP-2002202715-A (JP)
Title: Method for providing training on electric and electronic circuits
Inventor: KONDO SADAMU
IPC: G09B19/00
Filed: 2000-12-28
Abstract: PROBLEM TO BE SOLVED: To provide a method for providing training on electrical and electronic circuits by which training can be provided, so that not only electric circuits but also electronic circuits for electronic control can be understood comprehensively. SOLUTION: This method for providing training on electrical and electronic circuits comprises fundamental knowledge training steps 11-13 for providing training on the usage of a tester, electrical parts, and electrical circuits by using a text book, a tester, a training device for electrical and electronic circuits; and a circuit-training steps 14, 15 for providing training on electronic parts and electronic circuits by using the text book, the tester, and the training device for electrical and electronic circuits after the fundamental knowledge training steps 11-13. The fundamental knowledge training steps 11-13 includes a preliminary step 11 for learning electrical symbols and electrical circuits from the electrical symbols of the electrical parts shown in a learning guide means, and a direction of a current flow in the electrical circuit using these electrical symbols.  The circuit-training steps 14, 15 comprises a high voltage circuit study step 14 for training on relative high-voltage circuits, and a low-voltage circuit training step 15 for training on relative low-voltage circuits and digital circuits after the high-voltage circuit study step 14.
Patent JP-2002170982-A (JP)
Title: Photosensor circuit
Inventor: SHINOZUKA NORIYUKI
IPC: H04N5/369
Filed: 2000-12-01
Abstract: PROBLEM TO BE SOLVED: To provide a photosensor circuit from which a voltage signal having logarithmical characteristics can be taken out effectively depending on the quantity of incident light. SOLUTION: The photosensor circuit comprises a PN junction photodiode or phototransistor outputting a voltage signal exhibiting logarithmical voltage- current characteristics in a microcurrent region and varying logarithmically depending on the quantity of incident light.
Patent JP-2001510967-A (JP)
Title: 光学補正をしたホログラフィック・スクリーン・プロジェクション・テレビジョン
IPC: G03B21/62
Filed: 1998-01-29
Abstract: (57)【要約】
プロジェクション・スクリーン（２２）上に個別の色のそれぞれの画像を投影する少なくとも３つの画像プロジェクタ（１４，１６，１８）と、プロジェクタの１つ（１６）はスクリーン（２２）に対して実質的に垂直の方向に第一の光路（３２）を持ち、そして前記プロジェクタの少なくとも２つ（１４，１８）は入射角を規定する非垂直方向の光路で、第１の光路（３２）に向かって収束するそれぞれの光路（３４，３６）を持つように、その画像プロジェクタ（１４，１６，１８）とスクリーンに対して光学的連携を持って配置されているホログラフィック・ミラー（２０）とを含む光学システムを含むプロジェクション・テレビジョン（１０）を開示している。プロジェクション・スクリーン（２２）は、基板（２４）上に配置された３次元回折を示す３次元ホログラム（２６）から構成されている。スクリーンは第１の側面にプロジェクタ（１４，１６，１８）からの画像を受け、ディスプレイされた画像のすべてについて制御された光拡散を示して第２の側面上に前記画像をディスプレイする。
Patent JP-2001512108-A (JP)
Title: ビスイミノ−置換フェニル化合物
IPC: A01N43/653
Filed: 1998-07-20
Abstract: (57)【要約】
式Ｉ：
【化１】
 ［但し、Ｚが基Ａ又はＢ
【化２】
 ｛＃がフェニル環との結合を表し、
Ｒ a がハロゲン、アルキル又はアルコキシを表す｝を表し；
Ｙがハロゲン、アルキル、ハロアルキル又はアルコキシを表し；
ｎが０、１又は２を表し、且つｎが２である場合、基Ｙは相互に異なっていても良く；
Ｒ 1 がハロゲン、ハロアルキル又はアルコキシを表し；
Ｒ 2 がアルキル、ハロアルキル、アルケニル、ハロアルケニル、アルキニル又はハロアルキニルを表し；
Ｒ 3 がシアノ、アルキル、ハロアルキル、アルコキシ、シクロアルコキシ、アルコキシアルキル、
非置換又は置換のシクロアルキル、アリール、アリールオキシ、アリールメチレン、ヘテロアリール、ヘテロシクリル、
Ｃ（Ｒ 3a ）＝Ｎ−ＯＲ 3b 又はＣ（Ｒ 3a ）＝ＣＲ 3c Ｒ 3d 
｛Ｒ 3a 、Ｒ 3b 、Ｒ 3c 、Ｒ 3d が相互に独立して、それぞれ水素、アルキル又は非置換若しくは置換のフェニルを表す｝
を表す］
で表されるイミノ−置換フェニル化合物、その製造方法、及びその使用法。
Patent JP-2003527874-A (JP)
IPC: A61K31/77
Filed: 1998-08-27
Abstract: The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form following surgical procedures, are minimized. These materials contain a polymer of hydrophilic molecules such as polyethylene glycol (PEG) bound to a polymer that spontaneously adsorbs to biological tissue such as phenylboronic acid (PBA). The PEG-PBA co-polymer can be formed in a variety of geometries. The materials can also be used to coat prosthetics and other implants.
Patent JP-2001515844-A (JP)
Title: ３−デスクラジノース６−ｏ−置換エリスロマイシン誘導体
IPC: A61P31/04
Filed: 1998-09-01
Abstract: (57)【要約】
（Ｉ）、（ＩＩ）、（ＩＩＩ）、（ＩＶ）および（Ｖ）からなる群より選択される式で示される抗菌活性を有する新規多環式エリスロマイシン化合物および薬学的に許容できるその塩およびエステル、本発明の化合物の治療有効量を薬学的に許容できるキャリアと組み合わせて含む組成物、ならびに、式（Ｉ）〜（Ｖ）で示される化合物の治療有効量を含んでなる薬剤組成物を哺乳動物に投与することにより細菌感染を治療する方法。
【化１】
Patent JP-2001515075-A (JP)
Title: Ｈｆｇａｎ７２アンタゴニストとしてのフェニルウレアおよびフェニルチオウレア誘導体
IPC: A61P25/36
Filed: 1998-08-13
Abstract: (57)【要約】
式（Ｉ）：
【化１】
 ［式中：ＸおよびＹは、独立して、ＣＨまたは窒素である。ただし、ＸおよびＹが共にＣＨであることはない；Ｚは、酸素または硫黄であり；Ｒ 1 は、（Ｃ 1-6 ）アルキル、（Ｃ 2-6 ）アルケニルまたは（Ｃ 1-6 ）アルコキシであり、その中のいずれも置換されてもよく、あるいはハロゲン、Ｒ 7 ＣＯ−またはＮＲ 8 Ｒ 9 ＣＯ−であり；Ｒ 2 、Ｒ 3 、Ｒ 4 、Ｒ 5 およびＲ 6 は、独立して、（Ｃ 1-6 ）アルキル、（Ｃ 2-6 ）アルケニル、（Ｃ 1-6 ）アルコキシまたは（Ｃ 1-6 ）アルキルチオであり、その中のいずれも置換されてもよく、あるいは水素、ハロゲン、ニトロ、シアノ、アリールオキシ、アリール（Ｃ 1-6 ）アルキルオキシ、アリール（Ｃ 1-6 ）アルキル、Ｒ 7 ＣＯ−、Ｒ 7 ＳＯ 2 ＮＨ−、Ｒ 7 ＣＯＮ（Ｒ 10 ）−、ＮＲ 8 Ｒ 9 −、ＮＲ 8 Ｒ 9 ＣＯ−、−ＣＯＯＲ 8 またはヘテロシクリルであり；ただしＲ 2 、Ｒ 3 、Ｒ 4 、Ｒ 5 およびＲ 6 の少なくとも１個は水素以外であるか；または、隣接する一対のＲ 2 、Ｒ 3 、Ｒ 4 、Ｒ 5 およびＲ 6 がそれらが結合する炭素原子と一緒になって、置換されていもよい炭素環式または複素環式環を形成し；Ｒ 7 は、（Ｃ 1-6 ）アルキルまたはアリールであり；Ｒ 8 およびＲ 9 は、独立して、水素、（Ｃ 1-6 ）アルキル、アリールまたはアリール（Ｃ 1-6 ）アルキルであり；Ｒ 10 は、水素または（Ｃ 1-6 ）アルキルであり；またｎは、０、１、２、３または４である］で示されるフェニルウレアおよびフェニルチオウレア誘導体またはその医薬上許容される塩。本発明は、ヒトＨＦＧＡＮ７２レセプターの非−ペプチドアンタゴニストであるフェニルウレアおよびフェニルチオウレア誘導体を提供する。特に、かかる化合物は、２型糖尿病患者（非インスリン依存性）および／または睡眠障害と診断された肥満症を含む肥満の治療に有効である。
Patent JP-2001520042-A (JP)
Title: 改変型ビタミンｋ依存性ポリペプチド
IPC: C12N15/55
Filed: 1998-10-20
Abstract: (57)【要約】
本発明は、膜結合親和力が増強されたビタミンＫ依存性ポリペプチドを提供する。これらのポリペプチドは哺乳動物における血塊形成の調節に使用することができる。哺乳動物における血塊形成の調節方法も開示される。