baber/WOPTO huggingface dataset:
Patent CA-2439791-C (CA)
Inventor: RAHBAR SAMUEL
IPC: A61K31/17
Filed: 2002-03-05
Granted: 2010-10-19
Abstract: La présente invention concerne des produits terminaux de glycation avancée qui impliqués dans la pathogénie d'une gamme de maladies débilitante telles que le diabète, l'athérosclérose, la maladie d'Alzheimer et la polyarthrite rhumatoïde, ainsi que dans le processus normal de vieillissement. On a relevé sept composés susceptibles d'être actifs dans la rupture de formation de réseaux des protéines de produits terminaux de glycation avancée. Ces composés sont l'acide isobutyrique de 1,4-benzène-bis[4-méthylèneamino-phénoxy] (LR 102); l'acide benzoïque de 4-[(3,5-dichlorophényluréidophénoxyisobutyryl]-4-amino (LR 99); L-bis-[4-(4-chlorobenzamidophénoxyisobutyryl)cystine] (LR20); l'acide carboxylique de 4-(3,5-dichlorophényluréido)phénoxyisobutyryl-1amidocyclohéxane-1 (LR23); l'acide isobutyrique de méthylène bis[4,4'-(2-chlorophényluréidophénoxy)] (LR90); l'acide 5-aminosalicylique (5-ASA); et la metformine. Ces composés peuvent être utilisés pour inverser les effets débilitants de ces maladies dans lesquelles les produits terminaux de glycation avancée sont formés. FIG. 1A : A ABSORBANCE (410 nm) B PRODUITS TERMINAUX DE GLYCATION AVANCEE C PRODUITS TERMINAUX DE GLYCATION AVANCEE + LR-20 (1.0 mM) D PRODUITS TERMINAUX DE GLYCATION AVANCEE + LR-23 E PRODUITS TERMINAUX DE GLYCATION AVANCEE + LR-90 (1.0 mM) F PRODUITS TERMINAUX DE GLYCATION AVANCEE/SERUM ALBUMINE BOVIN (µg)
Patent CA-2440031-C (CA)
Inventor: RIPPERT DONALD J JR
IPC: G06F/
Filed: 2002-02-21
Granted: 2013-07-02
Abstract: Developing Internet-hosted business applications composed of web services and software for use in such environments where applications and application components interoperate to perform requested business functions. The invention utilize a software development application services provider module (DASP), an Instantiatior module, a Builder module, an Applications Service Provider (ASP) Infrastructure Platform (AIP) module, and a hosted production environment module. Developers and testers situated in diverse locations so that a larger pool of skilled people can be employed, the work can be done around the clock by using people all over the globe, and the costs can be reduced by directing work to people in countries with lower labor rates. The system and method of the present invention increases efficiencies and reduces costs to all parties by partnering the developers with third parties who are brought in at the beginning of development.
Patent CA-2440303-C (CA)
Title: Peptide modifie wt1
Inventor: SUGIYAMA HARUO
IPC: A61K35/15
Filed: 2002-03-22
Granted: 2013-03-19
Abstract: L'invention concerne un peptide antigène de cancer renfermant la séquence d'acides aminés suivante Cys-Tyr-Thr-Trp-Asn-Gln-Met-Asn-Leu (SEQ ID : 3) ; un vaccin contre le cancer renfermant ce peptide comme principe actif ; ainsi qu'un vaccin d'ADN renfermant un ADN codant ce peptide comme principe actif.
Patent CA-2446813-C (CA)
Title: Transferts graphiques a utiliser pour un moulage rotatif
Inventor: STEVENSON MICHAEL J
IPC: B28B1/02
Filed: 2002-05-17
Granted: 2012-02-14
Abstract: L'invention concerne un transfert d'empreinte et un procédé pour son utilisation, destiné à transférer une empreinte sur des objets polyoléfines durant un moulage rotatif. Le transfert est un stratifié constitué d'au moins trois revêtements sur une plaque de support, qui est de préférence une plaque polymère transparente souple. Les revêtements, disposés en couches successives sur la plaque de support sont: un revêtement de base d'un premier adhésif sensible à la pression, un revêtement d'empreinte d'un colorant de réseau graphique ou alphanumérique, et un revêtement supérieur d'un second adhésif sensible à la pression. L'adhésif sensible à la pression utilisé pour le revêtement de base présente une température de transition supérieure à la température de surface du moule sur lequel le transfert est appliqué, tandis que l'adhésif sensible à la pression, utilisé pour le revêtement supérieur, présente une température de transition inférieure à la température de surface du moule pour permettre le transfert des revêtements sur la surface intérieure d'un moule en rotation.
Patent CA-2448012-C (CA)
Inventor: DUDLEY WILLIAM R
IPC: H01M10/02
Filed: 2002-03-14
Granted: 2011-07-26
Abstract: Described are methods and products prepared from the methods, each of which include methods of coating certain materials onto a substrate, including coating a coating material and an edge material onto the substrate in a manner which may provide an improved thickness profile of the overall coating, and that may do so by using the edge material to augment the thickness of the coating material edge, or that may do so by improving the coating material edge by using the edge material to affect the shape of the coating material edge, the products being useful, for example, in electrochemical cells.
Patent CA-2448405-C (CA)
Inventor: HILSMAN YOUEL GILBERT
IPC: E21B33/12
Filed: 2003-11-06
Granted: 2007-08-07
Abstract: A subsurface annular safety barrier including a tubing disposed within a wellbore casing forming a casing-tubing annulus to allow fluid flow from and/or to a subterranean formation, and an annular barrier carried by the tubing and positioned in the casing-tubing annulus proximate the top of a formation, separating communication between the formation and the upper portion of the casing-tubing annulus above the annular barrier, wherein the annular barrier is set in an open position to allow fluid communication between the formation and the upper portion of the casing-tubing annulus and operationally activatable, without mechanical manipulation of a pipe string, to a closed position to prevent undesired fluid flow between the formation and upper portion of the casing-tubing annulus.
Patent CA-2450327-C (CA)
Inventor: REMMERS LEE E
IPC: A47B88/00
Filed: 2003-11-20
Granted: 2008-06-10
Abstract: A wire basket includes a storage portion and base portion removably connected and providing gliding operation. End caps connected to the storage portion allow for the removable connection. Gliding members having a curved portion and connected to the base portion allow for the gliding operation.
Patent CA-2453617-C (CA)
Inventor: ADAMS JOSEPH S
IPC: B25C1/08
Filed: 2003-12-17
Granted: 2007-08-21
Abstract: A new and improved valve assembly for incorporation within a dual combustion chamber system of a combustion-powered fastener-driving tool comprises a single valve mechanism which can operatively control the ingress of atmospheric air into the combustion chambers, the egress of combustion products out from the combustion chambers, and the fluid flows between the first and second combustion chambers attendant VENTING, MIXING, and FIRING stages of an overall combustion cycle. The valve mechanism may comprise either a rotary valve mechanism, a linear-rotary valve mechanism, or a linear valve mechanism.
Patent CA-2457646-C (CA)
Title: Frameless cabinet door system and method
Inventor: ANDERSON GARY
IPC: E05D7/08
Filed: 2004-02-12
Granted: 2007-07-10
Abstract: In accordance with the invention, a method and system is provided by which door panels are installed on the cabinet. A bottom support and a top support are installed to corner posts in the cabinet. A bottom door jamb is installed on the bottom support. Pivot pins are provided at a top and bottom of each of the right and left door panels. With the door panels upright, the respective bottom pivot pins are inserted in respective apertures of the bottom door jamb. An upper door jamb is positioned such that apertures of the upper door jamb are received over the respective top pivot pins of the right and left door panels. The upper door jamb is then attached to the top support.
Patent CA-2462346-C (CA)
Title: Method and apparatus for treating pig manure
Inventor: LACHAPELLE LUC
IPC: C02F1/38
Filed: 2004-03-24
Granted: 2012-05-22
Abstract: A method for the treatment of phosphorus containing waste waters, particularly pig manure, which comprises separating the waste water into a solids faction and a liquid faction, mixing the liquid faction with a mineral substance to reduce the phosphor content, and separating the liquid faction from the mineral substance. A preferred mineral substance is quarry fines.
Patent CA-2462965-C (CA)
Inventor: KILMER RAYMOND J
IPC: B21B1/38
Filed: 2002-10-22
Granted: 2010-09-14
Abstract: A method of casting a multi-layered metal ingot including the steps of delivering a metallic divider (14) member into a direct chill mold (4), pouring a first molten metal into the mold on one side of the divider member, and pouring a second molten metal into the mold on the other side of the divider member, and allowing the first molten metal and the second molten metal solidify to form a metal ingot (10) which includes the divider metal layer disposed there between.
Patent CA-2462968-C (CA)
Title: Method of setting and actuating a multi-stable micro valve and adjustable micro valve
Inventor: GINGGEN ALEC
IPC: F16K31/70
Filed: 2002-09-30
Granted: 2012-11-20
Abstract: A method for setting or actuating a micro valve for use in fluidic applications comprising the steps of cooling an array of actuating members made of SMA material, to a temperature equal or below the temperature at which a transformation from austenitic to martensitic state occurs so that the entire array of SMA actuating members is either fully or partially in the martensitic state, then selecting at least one of the actuating member corresponding to a pre-determined opening pressure or flow resistance and heating individually each of the actuating members except the previously selected one to a temperature equal or above to the temperature at which a transformation from the martensitic state to the austenitic state occurs. A micro valve having an array of actuating members made of shape memory alloy material is also disclosed.
Patent CA-2463842-C (CA)
Inventor: WAN YEW CHENG
IPC: E03B3/03
Filed: 2004-04-14
Granted: 2006-04-04
Abstract: Apparatus for the collection of rainwater falling over the seas by means of a catchment module consisting of a ring of floating booms connected by articulating means to form a flexibly connected polygonal shape. A flexible waterproof catchment bag for catching and storing; rainwater is suspended from the ring of booms. Tension ties constrain the booms to keep the bag open and to maintain the polygonal shape for modular assembly with other units. A plurality of modules may be joined together to form a large catchment network, which may be positioned at sea where rainfall is available by anchoring means as necessary. The flexibly connected booms enable the entire network to float rafted together for increased stability and allows passage of sea waves without generating excessive structural stresses in the structure. Suction tubes connected to pumps enable the collected water to be delivered to tanker vessels or pipe delivery systems.
Patent CA-2464111-C (CA)
Inventor: GRECO MICHAEL N
IPC: C07F9/572
Filed: 2002-10-17
Granted: 2013-03-12
Abstract: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
Patent CA-2465993-C (CA)
Inventor: MAGUIRE PATRICK G
IPC: E21B43/10
Filed: 2004-04-30
Granted: 2007-08-21
Abstract: The present invention generally relates to an apparatus and method for engaging a first tubular and a second tubular in a wellbore. In one aspect, an apparatus for forming an expanded connection in a wellbore is provided. The apparatus includes a first tubular radially expandable outward into contact with an inner wall of a second tubular upon the application of an outwardly directed force supplied to an inner surface of the first tubular. The apparatus further includes a plurality of outwardly extending formations formed on an outer surface of the first tubular, the formations constructed and arranged to provide a frictional relationship between the first tubular and the second tubular while leaving a fluid path when the first tubular is expanded to engage the inner wall of the second tubular. In another aspect, a method of compliantly expanding a tubular into contact with a casing wall is provided. In a further aspect, an expandable apparatus for expanding a tubular is provided.
Patent CA-2468845-C (CA)
Inventor: CONSTANTINIDES PANAYIOTIS P
IPC: A61K47/14
Filed: 2002-12-03
Granted: 2011-08-23
Abstract: Cette invention a trait à des compositions, ainsi qu'aux méthodes correspondantes, permettant une libération de médicament apte à faciliter l'absorption desdits médicaments à travers des muqueuses, notamment des médicaments dotés d'une faible biodisponibilité intrinsèque, tels que des peptides, des protéines, des vaccins et des acides nucléiques. Le système de libération selon l'invention contient, de préférence, des esters d'acides gras ainsi que leurs dérivés hydrophiles s'associant avec de l'eau et d'autres solvants polaires pour former des micelles inverses stables. Apportées sous forme de produit pharmaceutique sur des surfaces muqueuses, après ingestion orale ou administration par voie nasale, les molécules bio-actives principalement solubilisées dans la phase hydrophile, qui sont protégées contre une digestion par des enzymes des muqueuses et autre processus de dégradation par les muqueuses, sont prises en charge par des mécanismes d'absorption cellulaire et atteignent les régions corporelles auxquelles elles sont affectées. Ces compositions à base de micelles inverses peuvent contenir des monoglycérides et/ou leur produits transestérifiés renfermant des chaînes d'acides gras porteurs de 6 à 12 atomes de carbone, les groupes transester se composant de fractions hydrophiles.
Patent CA-2472295-C (CA)
Title: Metallic beverage can end with improved chuck wall and countersink
Inventor: NGUYEN TUAN A
IPC: B65D8/20
Filed: 2003-01-10
Granted: 2011-11-29
Abstract: A beverage can end (2) has a chuck wall (6), inner panel (16) and central panel (14). A concave arch on the chuck wall (6) with a radius of curvature between about 0.015 inches and 0.080 inches.
Patent CA-2472990-C (CA)
Inventor: KRUMM JOHN C
IPC: H04W64/00
Filed: 2004-07-02
Granted: 2013-09-03
Abstract: The present invention leverages changes in the sensed strength of radio signals at different locations to determine a device's location. In one instance of the present invention, inference procedures are used to process ambient commercial radio signals, to estimate a location or a probability distribution over the locations of a device. Tn another instance of the present invention, a system utilizes learning and inference methods that are applied to rank vector of signal strength vectors. Moving to such rank orderings leads to systems that bypass consideration of absolute signal strengths in location calculations. The present invention facilitates approximations for locating a device by providing a system that does not require a substantial number of available ambient signal strengths while still providing useful location inferences in determining locations.
Patent CA-2474991-C (CA)
Inventor: ANDERSON TERRY
IPC: E21B19/22
Filed: 2004-07-07
Granted: 2008-04-29
Abstract: An oil well servicing vehicle includes a mobile support structure having ground engaging wheels. The mobile support has a first end, a second end and opposed sides. A support mast is pivotally mounted at the second end of the mobile support for movement between a substantially vertical operative position and a substantially horizontal transport position. The support mast supports a flushby line support and a coil tubing support. A winch is mounted on the mobile support and adapted to feed flushby line over the flushby line support on the support mast. At least one coil tubing drum is mounted on the mobile support and adapted to feed coil tubing over the coil tubing support on the support mast. This vehicle is capable of performing the tasks of both a flushby unit and a coil tubing unit.
Patent CA-2475474-C (CA)
Inventor: HUGO GERD
IPC: C09D5/33
Filed: 2003-01-28
Granted: 2012-04-03
Abstract: The invention relates to a plane metal component, the outer surface thereof being coated such that it reflects sunlight in the near-infrared region, and the inner surface thereof having low thermal emissivity.
Patent CA-2479975-C (CA)
Title: Tool for use with a medication vial and/or a syringe
Inventor: LYMAN SCOTT D
IPC: B67B7/16
Filed: 2004-09-01
Granted: 2008-04-01
Abstract: A tool for use with a medication vial and a syringe comprises a housing having a top side, a bottom side, and a surrounding edge, a slotted aperture defined in the housing and including a flange shaped to engage vial cap, a cylindrical aperture defined in the housing and sized to permit placement of a forward portion of the syringe including a cap into the cylindrical aperture; an actuator button mounted to the housing, and a gripper, mounted within the housing and having a pair of opposed edges, with the gripper responsive to movement of the actuator button to permit movement of the ages between a retracted position in which the edges are disposed away from a central portion of the cylindrical aperture, and an extended position in which the edges are displaced toward the central portion of the cylindrical aperture.
Patent CA-2480672-C (CA)
Title: Suction sequences for a breastpump
Inventor: GRETER ANDY
IPC: A61M1/06
Filed: 2003-04-02
Granted: 2012-11-27
Abstract: A breastpump is provided with one or more navel suction sequences which are considered to produce advantageous particularized results. Such sequences include a suction method for increased milk production and an improved suction method in general.
Patent CA-2484816-C (CA)
Title: Halo-alkyl esters of camptothecins and methods of treating cancer using these compounds
Inventor: CAO ZHISONG
IPC: A61K31/4375
Filed: 2003-04-22
Granted: 2011-06-07
Abstract: Halo-alkyl esters of camptothecin are described. Processes for making these compounds and for using them in cancer treatment, are also described.
Patent CA-2486379-C (CA)
Title: Reacteurs a section transversale variable, procedes permettant de produire ceux-ci, et procede permettant de produire des reactions avec des temps de contact local variables
Inventor: WANG YONG
IPC: B01L3/00
Filed: 2003-05-21
Granted: 2013-11-12
Abstract: L'invention concerne des procédés permettant d'effectuer des réactions chimiques dans un conduit à réaction présentant une section de dimension variable, de manière à varier le temps de contact local d'un ou de plusieurs réactifs chimiques pendant leur écoulement à travers le conduit. Cette invention concerne également des réacteurs équipés de conduits à réaction présentant des sections variables. Dans une forme de réalisation préférée, la section du conduit à réaction présente une forme trapézoïdale qui s'élargit progressivement de l'entrée à la sortie.
Patent CA-2486779-C (CA)
Title: Method for assembling/dismounting components of a wind power plant
Inventor: WOBBEN ALOYS
IPC: F03D1/06
Filed: 2003-05-23
Granted: 2009-02-03
Abstract: The present invention concerns a wind power installation and a method of fitting/removing components of a wind power installation. So that a crane is tied in to a lesser degree in fitting/removing components of a wind power installation, in a wind power installation according to the invention at least one cable passage means is provided in the region of the pylon head for passing through a hauling cable from a winch. The object is further attained by a method of fitting/removing components of a wind power installation comprising the steps: - laying a hauling cable from the winch to at least one deflection roller in the region of the pylon head and further to the component to be fitted/removed, - attaching the hauling cable to the component, and - releasing and letting down or pulling up and fixing the component. In that respect the invention is based on the realisation that at least a part of the components of a wind power installation can be fitted or replaced even without the aid of a crane if a suitable lifting apparatus is available. The solution according to the invention avoids expensive and complicated additional installations on any wind power installation. Nonetheless a versatile lifting apparatus is quickly available at low cost.
Patent CA-2487297-C (CA)
Title: The use of substituted cyanopyrrolidines and combination preparations containing them for treating hyperlipidemia and associated diseases
Inventor: HOLMES DAVID GRENVILLE
IPC: A61K31/22
Filed: 2003-06-02
Granted: 2011-08-09
Abstract: Disclosed are methods and compositions for the treatment of hyperlipidemia and conditions associated therewith, such as CHD, ischemic stroke, restenosis after angioplasty, peripheral vascular disease, intermittent claudication, myocardial infarction (e.g. necrosis and apoptosis), dyslipidemia and post-prandial lipemia. The methods include administration of a therapeutically effective amount of a compound of formula (I), wherein R is substituted adamantyl; and N is 0 to 3; in free form or in acid addition salt form, and a pharmaceutically acceptable carrier.
Patent CA-2488590-C (CA)
Title: Ink ribbon cartridge
Inventor: YAMAMOTO HIDEKI
IPC: B41J32/00
Filed: 2004-11-30
Granted: 2012-08-07
Abstract: An ink ribbon cartridge including a frame, supply shaft supporting members and take-up shaft supporting members is provided. The supply shaft supporting members support a supply shaft, and the take-up shaft supporting members support a take-up shaft. The frame includes a first bearing member, a second bearing member, a front connecting member, which connects front ends of the first and second beating members together, and a back connecting member connects back ends of the first and second bearing members together. At least one of the front connecting member and the back connecting member has one of a groove or a hole capable of accommodating a portion of an image forming device in which the ink ribbon cartridge may be installed.
Patent CA-2489667-C (CA)
Title: Appareil de chauffage a positions multiples
Inventor: RIEPENHOFF MATTHEW S
IPC: F24H8/00
Filed: 2004-12-07
Granted: 2013-04-16
Abstract: Un appareil de chauffage offre des positions multiples pour le fonctionnement à circulation descendante, le fonctionnement à circulation ascendante, le fonctionnement à circulation horizontale à gauche ou le fonctionnement à circulation horizontale à droite sans modifications majeures sur place. L'appareil de chauffage comprend un système de drainage de condensat à positions multiples qui facilite le drainage du fluide de condensat, peu importe l'orientation de l'appareil de chauffage. Le système de drainage de condensat comprend un collecteur de tête et un collecteur d'échappement, chacun comprenant un nombre d'orifices de drainage qui permet au fluide condensé des gaz de combustion d'être drainé, peu importe l'orientation de l'appareil de chauffage. Un purgeur est configuré comme accessoire de l'appareil de chauffage dans n'importe quelle des quatre positions différentes et reçoit le fluide de condensat du collecteur de tête et du collecteur d'échappement. Un collecteur d'entrée d'air est spécialement configuré pour maintenir un profil bas, ce qui facilite l'utilisation du système de drainage de condensat à positions multiples.