baber/WOPTO huggingface dataset:
Patent ES-2305110-T3 (ES)
Title: Anticuerpos contra la il-1 beta humana.
Inventor: GRAM HERMANN
IPC: A61K39/395
Filed: 2001-08-20
Granted: 2008-11-01
Abstract: Una molécula de enlazamiento a la IL-1beta que comprende tanto a los dominios variables de cadena liviana (VL) como de cadena pesada (VH) en los cuales dicha molécula de enlazamiento a la IL-1beta contiene al menos un sitio de enlazamiento del antígeno que comprende: a) un dominio variable de cadena pesada de inmunoglobulina (VH) que comprende a las regiones hipervariables en secuencia CDR1, CDR2 y CDR3, dicha CDR1 teniendo la secuencia de aminoácidos Val-Tyr-Gly- Met-Asn, dicha CDR2 teniendo la secuencia de aminoácidos Ile-Ile-Trp-Tyr-Asp-Gly-Asp-Asn-Gln-Tyr- Tyr-Ala-Asp-Ser-Val-Lys-Gly, y dicha CDR3 teniendo la secuencia de aminoácidos Asp-Leu-Arg-Thr-Gly- Pro; y b) un dominio variable de cadena liviana de inmunoglobulina (VL) que comprende a las regiones hipervariables en secuencia CDR1'', CDR2'' y CDR3'', dicha CDR1'' teniendo la secuencia de aminoácidos Arg-Ala-Ser- Gln-Ser-Ile-Gly-Ser-Ser-Leu-His dicha CDR2'' teniendo la secuencia de aminoácidos Ala-Ser-Gln-Ser- Phe-Ser y dicha CDR3'' teniendo la secuencia de aminoácidos His-Gln-Ser-Ser-Ser-Leu-Pro; y los equivalentes directos de los mismos en los cuales las regiones hipervariables CDR1, CDR2, CDR3, CDR1'', CDR2'' y CDR3'' tomadas como un todo son al menos 95% homólogas a las regiones hipervariables bajo a) y b), y tienen una especificidad de enlazamiento por el epítopo antigénico de la IL-1beta que incluye al bucle que incluye al residuo Glu 64 de la IL-1beta madura humana.
Patent ES-2258563-T3 (ES)
Inventor: DI PIERRO FRANCESCO
IPC: A61K8/73
Filed: 2001-11-14
Granted: 2006-09-01
Abstract: Pharmaceutical and/or cosmetic compositions for the treatment and the prevention of scalp disorders, containing as active components extracts of Serenoa repens and of Vitis vinifera.
Patent ES-2320976-T3 (ES)
Title: Cabeza impresora de chorro de tinta y metodo para la misma.
Inventor: TORGERSON JOSEPH M
IPC: B41J2/06
Filed: 2001-10-29
Granted: 2009-06-01
Abstract: Una cabeza (24) impresora que tiene una pluralidad de generadores (42, 42'') de goteo que expulsan tinta selectivamente en respuesta a la activación, comprendiendo la cabeza impresora de chorro de tinta: primero y segundo generadores de goteo dispuestos sobre la cabeza impresora con cada uno de los generadores primero y segundo de goteo configurados para la conexión a una fuente de corriente de accionamiento; un par de contactos (26) de activación configurados para la conexión a una fuente de un par de señales de activación periódica en donde dicho par de contactos de activación son los contactos de activación únicos de la cabeza impresora de chorro de tinta; un dispositivo de control configurado para la conexión a una señal de direccionamiento periódico y al par de señales de activación periódica, comprendiendo el dispositivo de control un primer dispositivo (48, 50, 52) de control asociado con el primer generador de goteo y un segundo dispositivo (48'', 50'', 52'') de control asociado con el segundo generador de goteo, siendo el primer dispositivo de control sensible a una primera señal de activación periódica del par y a la señal de dirección periódica para preparar el primer generador de goteo para la activación en respuesta a la corriente de activación, y sensible a una segunda señal de activación periódica del par para desactivar el primer generador de goteo, el segundo dispositivo de control sensible a la segunda señal de activación periódica y la señal de dirección periódica para activar el segundo generador de goteo para la activación en respuesta a la corriente de accionamiento y sensible a la primera señal de activación periódica para desactivar el segundo generador de goteo.
Patent ES-2256343-T3 (ES)
Inventor: PRITZER WOLFGANG
IPC: F16B7/08
Filed: 2002-01-31
Granted: 2006-07-16
Abstract: A ring connects two rotationally symmetrical structural parts to form a rotationally symmetrical light-weight structure. At the transition between the two structural parts, there is a change of the slope of the meridian line of the light-weight structure. The ring comprises a surrounding layer of carbon fiber reinforced plastic CFRP with carbon fibers oriented in a circumferential direction of the structural parts.
Patent ES-2249510-T3 (ES)
Inventor: TACIES CAPDEVILA ANNA
IPC: D06M23/12
Filed: 2002-04-30
Granted: 2006-04-01
Abstract: Fibres and textile sheet, treated with preparations of (a) micro-encapsulated active substances which also contain (b) binders.  Independent claims are also included for methods for the treatment of fibres and textiles by impregnation of the substrate with an aqueous preparation containing (a) and (b), or by forced application of such a preparation to the substrate.
Patent ES-2236390-T3 (ES)
Inventor: AZOULAI CHAIM
IPC: E06B9/165
Filed: 2002-05-21
Granted: 2005-07-16
Abstract: It is provided a shutter assembly for an aperture, comprising: a plurality of adjacent elongate slats (20) coupled together to form a slat assembly, said slats (20) having: a lower edge; a lower channel (38) along the lower edge, said lower channel (38) being defined by at least one inwardly directed lower lip (40,42); an upper edge; and at least one upper channel (52) along at least part of the upper edge, said upper channel each being defined by at least one inwardly directed upper lip (34,36); wherein said slats (20) are coupled to an adjacent slat (20) in the shutter assembly by at least two coupling linkages (44), said coupling linkages (44) having upper and lower hooked heads (46,46'); and wherein said inwardly directed lips (34,36; 40,42)and said hooked heads (46,46') are mutually configured such that said upper hooked heads (46) are captured within the lower channel (38) of an adjacent slat (20) by said at least one lower lip (40,42), and said lower hooked heads (46') are captured within the at least one upper channel (52) of an adjacent slat (20) by said at least one upper lip (34,36). <IMAGE>
Patent ES-2301598-T3 (ES)
Inventor: HEIKAUS GERD
IPC: B65B11/04
Filed: 2002-10-01
Granted: 2008-07-01
Abstract: Wrapping device for wrapping objects, especially arranged on a pallet, with foil comprises a roll holder for a foil roll, a guide device for guiding the foil unwound from the foil roll, a pressure roller (42) pressing against the guide device to tension the foil, a first braking element (64) connected to the pressure roller and against which a second braking element (66) is pressed to tension the foil, and a clamping device for clamping the braking elements together. The clamping device has a clamping lever (46) that when actuated into a braking position generates a defined braking force between the braking elements. An independent claim is also included for a braking device (44) for a winding device.
Patent ES-2261578-T3 (ES)
Inventor: FUSER SVEN DR-ING
IPC: B61F19/04
Filed: 2002-11-07
Granted: 2006-11-16
Abstract: Collision protection device for rail vehicles without side buffers at the front comprises energy-absorbing elements (1) arranged in the usual region of the side buffers and suitable for coming into contact with the buffer plate of the side buffers (2) of a second rail vehicle. The energy-absorbing element is designed as a pot (1a) whose opening faces forward in the impact direction and is filled with energy-absorbing material. The pot is fixed to a pressure piece (5) which is connected to the rail vehicle body over a stage (7) so that it can be longitudinally displaced relative to the rail vehicle body (6) to absorb additional deformation energy. Devices for the driver including his seat (8) fixed on the pressure piece are longitudinally displaced together with the pressure piece into the vehicle interior. <??>Preferred Features: The pot has a load-bearing casing forming a longitudinal guide and preventing lateral yielding of the penetrating side buffer.
Patent ES-2305182-T3 (ES)
Inventor: JACOBSSON THOMAS
IPC: G10H1/18
Filed: 2002-09-02
Granted: 2008-11-01
Abstract: A sound synthesiser is provided that reduces the computational requirements of a synthesiser with a high degree of polyphony, while ensuring that audible artefacts are kept to a minimum. The synthesiser comprises a plurality of samples stored in a memory; a plurality of voices each comprising means for calculating an output using a plurality of samples selected from the plurality of samples stored in the memory; wherein a voice is active when calculating an output; wherein the number of samples selected by the means for calculating depends upon the number of active voices. <IMAGE>
Patent ES-2266419-T3 (ES)
Inventor: WANG WEI-CHENG
IPC: A61H39/08
Filed: 2002-12-06
Granted: 2007-03-01
Abstract: A computer-aided automatic vital acupuncture point alignment and electronic acupuncture method uses a system to perform the method comprised of a computer (10), a digital imaging device (20), a digital probe device (40) and an electronic acupuncture device (30). The computer (10) takes a picture of a patient's body with the digital imaging device (20) and automatically marks vital acupuncture points on the picture from a standard body's picture on which all vital acupuncture points are marked and localizes the vital acupuncture points on the patient's skin with the digital probe device (40). A practitioner uses the electronic acupuncture device (30) to touch the vital acupuncture points on the patient's skin based on the patient's picture. The computer (10) outputs a suitable wave signal through the electronic acupuncture device (30) to the skin. <IMAGE>
Patent ES-2276922-T3 (ES)
Inventor: ERLANDSSON FREDRIK
IPC: G01N33/483
Filed: 2002-01-24
Granted: 2007-07-01
Abstract: The invention is a method that allows the detection of cancer cells in a cell or tissue sample. One step in the invention is the determination of whether there are cells in the S- or G2-phases of the cell cycle in the sample that contain "cyclin E-type-protein". The method is based on a determination of the level of "cyclin E-type-protein" in the individual cells in the sample together with a determination of the level of a "post G1-substance", i.e. a substance present exclusively in S and/or G2 cells. The sample can be assumed to contain cancer cells if "cyclin E-type-protein" is found in cells in S and/or G2. A high percentage of cells containing "cyclin E-type-protein" in S and/or G2 is an indication that the tumour cells are highly malignant
Patent ES-2230488-T3 (ES)
Title: Procedimiento de preparacion de un refinado parafinado.
Inventor: GERMAINE GILBERT ROBERT BERNAR
IPC: C10G65/04
Filed: 2002-03-05
Granted: 2005-05-01
Abstract: Procedimiento para preparar un producto refinado ceroso mediante: (a) hidrocraqueo/hidroisomerización de una materia de origen Fischer-Tropsch, en el que la proporción de peso de los compuestos que tienen al menos 60 ó más átomos de carbono y de los compuestos que tienen al menos 30 átomos de carbono del producto Fischer-Tropsch es al menos 0, 4 y en el que al menos el 30% en peso de los compuestos de la materia de origen Fischer-Tropsch tiene al menos 30 átomos de carbono, (b) aislamiento del producto de la etapa (a) de un producto refinado ceroso que tiene un punto de ebullición T10 % en peso de entre 200 y 450º C y un punto de ebullición T90 % en peso de entre 400 y 650º C.
Patent ES-2266491-T3 (ES)
Title: Dispositivo de refrigeracion para un generador de turbina de viento.
Inventor: WOBBEN ALOYS
IPC: H02K9/22
Filed: 2002-04-18
Granted: 2007-03-01
Abstract: Instalación de energía eólica con un generador anular (16) y una carcasa (12, 14) de la góndola de la instalación de energía eólica que rodea el generador anular, presentando la carcasa (12, 14) de la góndola en la zona del generador anular una sección termoconductora (20) de carcasa y estando configurada una distancia determinada entre el contorno exterior del generador anular (16) y la sección termoconductora (20) de carcasa, caracterizada porque la sección termoconductora (20) de carcasa se compone de un material distinto al resto de la carcasa de la góndola.
Patent ES-2258628-T3 (ES)
Title: Vacunas vectoras a base de leporipox.
Inventor: SPIBEY NORMAN
IPC: A61K48/00
Filed: 2002-03-07
Granted: 2006-09-01
Abstract: Uso de un virus leporipox vivo recombinante que contiene ADN exógeno, que está operablemente unido a al menos un elemento de control de la expresión y que se incorpora a una región no esencial del genoma del virus, en la fabricación de una vacuna vectora para el tratamiento y/o la profilaxis de enfermedades infecciosas en especies no lepóridas.
Patent ES-2295351-T3 (ES)
Inventor: HOERR INGMAR
IPC: C12N15/89
Filed: 2002-04-21
Granted: 2008-04-16
Abstract: The invention relates to a device for injecting a material containing RNA into an organism, in particular for immunisation purposes and to the use of dehydrated RNA as vaccines.
Patent ES-2283584-T3 (ES)
Inventor: BAUMGARTNER HEINRICH GEORG
IPC: B22C9/08
Filed: 2002-07-15
Granted: 2007-11-01
Abstract: A die particularly for on-road vehicle wheels, of the type that comprises lower, upper and lateral die parts that form an impression to be filled with molten material, comprising at least two die filling points arranged at two openings of the design of a wheel where the lower die part and the upper die part are in contact when the die is in the closed configuration.
Patent ES-2315400-T3 (ES)
Inventor: JONES DAVID P
IPC: A61K8/92
Filed: 2002-07-29
Granted: 2009-04-01
Abstract: A topical ointment pharmaceutical composition that uses a lipophilic base, a pharmaceutical active and, dispersed in the base, from about 1% to about 50% by weight of the total composition of hydrogenated non-melted castor oil in powder form. The result of using hydrogenated non-melted castor oil in powder form is a surprising pharmaceutical elegance perceived to be smoother in texture and more spreadable than an ointment made by melting the hydrogenated castor oil.
Patent ES-2248610-T3 (ES)
Inventor: DEAN DAVID KENNETH
IPC: A61P9/10
Filed: 2002-05-20
Granted: 2006-03-16
Abstract: The present invention relates to compounds of formula (I): pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, use as Raf Kinase Inhibitors and treatment methods for neurotraumatic diseases and cancer.
Patent ES-2290340-T3 (ES)
Inventor: COVELLI BRUNO
IPC: A61F2/24
Filed: 2002-09-04
Granted: 2008-02-16
Abstract: An in vitro method for preparing homologous heart valves (A), is new.  An in vitro method for preparing homologous heart valves (A) comprises: (a) preparation of a biodegradable carrier (scaffold);  (b) seeding the carrier with homologous fibroblasts and/or myofibroblasts to form a connective tissue matrix;  (c) optionally seeding the matrix with endothelial cells and  (d) fixing the matrix to a framework (stent) that is not (easily) degraded. The matrix, before and/or after fixing, is introduced into a pulsatile flow chamber and the flow rate in the chamber increased (dis)continuously. Independent claims are also included for: (1) similar method in which the carrier and stent are fixed together before seeding with cells;  (2) autologous heart valves prepared by the method; and (3) autologous heart valves having a connective tissue inner structure, surrounded by a layer of endothelial cells and fixed to a stent.
Patent ES-2242893-T3 (ES)
Title: Sistema medico de suspension con dos arboles giratorios.
Inventor: WAGNER JORG
IPC: A61G12/00
Filed: 2002-11-05
Granted: 2005-11-16
Abstract: Sistema (10) de suspensión para suspender una pluralidad de dispositivos desde una estructura de soporte que comprende una placa (30) de techo configurada para fijarse a la estructura (16) de soporte, un primer árbol giratorio (40), portado por la placa de techo, estando configurado el primer árbol giratorio para sostener sobre él por lo menos un primer dispositivo (12), caracterizado por: una placa adaptadora (62) configurada para montarse en la placa de techo; un segundo árbol giratorio (60) portado por la placa adaptadora, estando configurado el segundo árbol giratorio para sostener sobre él por lo menos un segundo dispositivo (14, 14¿).
Patent ES-2242909-T3 (ES)
Title: Dispositivo de estanqueidad para una junta de dilatacion.
Inventor: FIEGER FRANK
IPC: E01D19/06
Filed: 2003-02-26
Granted: 2005-11-16
Abstract: Dispositivo de estanqueidad (1a, 1b) para una junta de dilatación (2) entre dos elementos de construcción (4) con una unidad de puenteo (13a) flexible y dos unidades de anclaje (8a, 8b) dispuestas en los lados opuestos de la junta de dilatación (2), que presentan en cada caso una brida fija (9a) que puede unirse al elemento de construcción (4) asociado y una brida libre (10a, 10b), que puede arriostrarse por medio de un elemento de apriete (11a, 11b) con la brida fija (9a) a modo de una unión de cola de milano, pudiéndose unir la unidad de puenteo (13a) con las unidades de anclaje (8a), de tal modo que esté apretada en cada caso entre la brida fija (9a) y la brida libre (10a, 10b), caracterizado porque el elemento de apriete (11a, 11b) presenta fundamentalmente la misma resistencia que la brida fija (9a).
Patent ES-2261833-T3 (ES)
Inventor: GRESS WOLFGANG
IPC: C09K3/22
Filed: 2003-08-20
Granted: 2006-11-16
Abstract: Production of a dust reduced aerator for mortar, plaster,cement, concrete comprises granulating a powdered aerator with an aqueous solution or dispersion of an alkali metal or ammonium (meth)acrylate (co)polymer. An Independent claim is also included for a dust reduced aerator produced as above.
Patent ES-2265547-T3 (ES)
Inventor: TAGLIAVENTO MAURO
IPC: B65G13/07
Filed: 2003-11-14
Granted: 2007-02-16
Abstract: The present invention relates to a modular system for handling motor vehicle bodyworks and the like, which comprises a drive module (2) defining a central frame (3) coupled to cross frames (4). <??>The central frame (3) comprises motion transmission mechanisms (10-14), which are driven by an outer gear motor unit (13) and are coupled to cross shafts (22) supported by the cross frames (4). <??>The cross shafts (22) drive, in turn, wheels (30) for driving skid assemblies (40) for conveying motor vehicle bodyworks and the like. <IMAGE>
Patent ES-2276024-T3 (ES)
Inventor: NICLAS ANDRE
IPC: B21K1/76
Filed: 2003-03-26
Granted: 2007-06-16
Abstract: The connecting rod (1) is made from a blank cut from a rail of the required cross-section, having a head, body and foot. The blank is compressed between matrices to distribute the material and produce a rough connecting rod with no burrs, and bores (3, 7) are made in the head and foot by heating the blank to a temperature of between 0 and 1250 deg C and applying a stamping press or punch.
Patent ES-2276051-T3 (ES)
Inventor: DOTTA ANGELO
IPC: E04H6/22
Filed: 2003-04-15
Granted: 2007-06-16
Abstract: A storage installation comprising at least one basic installation or module (2a, 2b), each module including: 5 -a lift (50) equipped with a quadrangular platform (11) and with means (51-59) to move said platform (11) along a vertical shaft (12) to make said platform take several positions corresponding to different levels (Ll, L2...Ln) along said shaft; -a plurality of boxes ( 13) located at each of said different levels 10 and arranged around the lift shaft, one side of each box being adjacent to a corresponding side of the shaft, each box being arranged to house a trolley (14) on which the object(s) to be stored is (are) placed; -means for translating the trolleys and allowing trolley loading 15 and unloading onto and from the platform according to mutually perpendicular directions, by following suitable guides (16) intersecting onto the platform itself.
Patent ES-2303588-T3 (ES)
Inventor: STRAKA CHRISTIAN
IPC: C12Q1/00
Filed: 2003-03-24
Granted: 2008-08-16
Abstract: The present invention relates to a method for determining the hematopoietic cytocapacity of a subject comprising the steps of: (a) determining the amount of leukocytes present in a blood sample obtained from a subject, wherein said subject has been subjected to administration of a single dose of G-CSF; and (b) determining the hematopoietic cytocapacity by assessing the amount of leukocytes determined instep (a) with the amount of leukocytes which have been mobilized or released in a control subject wherein said control subject.
Patent ES-2395266-T3 (ES)
Title: Etiqueta RFID en la que se puede formar una imagen por láser
Inventor: SAINT ANDRE
IPC: G06K19/04
Filed: 2003-04-18
Granted: 2013-02-11
Abstract: Conjunto de láminas de identificación electrónica en el que se puede formar una imagen (11), quecomprende:una lámina base (15);una lámina de cobertura (17);una lámina de máscara (19) en la que hay formada una ventana (21), y la lámina de máscara (19) está adheridaentre las láminas de base (15) y de cobertura (17),en el que la lámina de máscara (19), la lámina base (15) y la lámina de cobertura (17) forman un bolsillo protector(23) dentro de la ventana (21) para proteger un circuito electrónico (25) adherido completamente dentro del bolsilloprotector (23) que lo protege del calor y la presión aplicados por la impresora láser (13) cuando se imprime unaimagen en la lámina de cobertura (17); y un dispositivo de transmisión dentro del bolsillo protector (23) paratransmitir información de identificación desde el circuito electrónico (25) a un transceptor externo (31) fuera delbolsillo protector (23);caracterizado porquela lámina base (15) y la lámina de cobertura (17) poseen un espesor comprendido en el intervalo de 0,076 a 0,1013mm (de 3 a 4 milésimas de pulgada),la lámina de máscara (19) posee un espesor en el intervalo de 0,076 a 0,2027 mm (de 3 a 8 milésimas de pulgada),yel conjunto de láminas (11) tiene un espesor menor de 0,38 mm (15 milésimas de pulgada).
Patent ES-2276064-T3 (ES)
Inventor: MAYER JOSEF
IPC: B65B5/10
Filed: 2003-01-10
Granted: 2007-06-16
Abstract: The device comprises an aligning belt (1) which conveys products (2) whilst transferring them at a transfer edge (4) to a portioning belt (3) on which the portions (6) are shaped or sized and moved onward in corresponding sizes. The position of the transfer edge can be changed relative to the portioning belt in at least one direction. The position of the transfer edge and movement of the belt are matched so that any sized product and size can be produced. The device has a control through which the desired portions and sizes can be freely programmed and filed.
Patent ES-2605401-T3 (ES)
Title: Elementos separadores y de junquillo para unidades de acristalamiento aislante
Inventor: REICHERT GERHARD
IPC: E06B3/663
Filed: 2003-07-03
Granted: 2017-03-14
Abstract: Un separador (300) adaptado para ser dispuesto entre láminas opuestas (18, 20) de vidrio en una unidad de acristalamiento y para mantener una cámara aislante (306) entre las láminas (18, 20) de vidrio, comprendiendo el separador (300) un cuerpo (304) fabricado a partir de un material de espuma, caracterizado por que el cuerpo (304) define una pluralidad de cavidades aislantes cerradas, espaciadas, (302), prolongándose cada una de las cavidades aislantes (302) continuamente en una dirección longitudinal del cuerpo (304); en donde cada cavidad aislante (302) tiene una anchura, siendo el espacio (314) entre las cavidades aislantes (302) igual a, o mayor que, la anchura de cualquier cavidad aislante (302).
Patent ES-2331733-T3 (ES)
Inventor: DUMIC MILJENKO
IPC: A61K/
Filed: 2003-03-18
Granted: 2010-01-14
Abstract: A substantially pure isostructural pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A having the Formula I:    
wherein S is an organic solvent which is at least partially miscible with water, x is 1, y is 0, 0.5, or 1, the pseudopolymorph being characterized by the monoclinic space group  P 2 1  and average unit cell parameters comprising: crystal axis lengths of a = 15.5 - 17.0 Å, b = 15.5 - 17.0 Å and c = 17.5 - 19.5 Å, and angles between the crystal axes of ± = ³ = 90° and ² = 106° - 112°.