baber/WOPTO huggingface dataset:
Patent CA-2846197-A1 (CA)
Inventor: LIPSON DORON
IPC: C12N15/113
Filed: 2012-08-23
Abstract: Novel RET fusion molecules and uses are disclosed. In one embodiment, a KIF5B-RET fusion includes an in-frame fusion of an exon of KIF5B (e.g., one more exons encoding a kinesin motor domain or a fragment thereof) and an exon of RET (e.g., one or more exons encoding a RET tyrosine kinase domain or a fragment thereof). For example, the KIF5B-RET fusion can include an in-frame fusion of at least exon 15 of KIF5B or a fragment thereof (e.g., exons 1-15 of KIF5B or a fragment thereof) with at least ex on 12 of RET or a fragment thereof (e.g., exons 12-20 5 of RET or a fragment thereof).
Patent CA-2846322-A1 (CA)
Title: Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
Inventor: FRIEDRICH GLENN
IPC: A01K67/027
Filed: 2012-09-18
Abstract: The invention provides improved non-human vertebrates and non-vertebrate cells capable of expressing antibodies comprising human variable region sequences. The present invention is directed to the provision of long HCDR3s from non-human vertebrates and cells. The present invention is also directed to the provision of novel V, D and J pairings in immunoglobulin heavy and light chain loci. Novel, biased antibody diversities and potentially expanded diversities are provided. The invention also provides for novel and potentially expanded diversity or diversity that is biased towards variable gene usage common to antibodies useful for treating and/or preventing certain diseases or conditions, such as infectious diseases. The invention also provides methods of generating antibodies using such vertebrates, as well as the antibodies per se, therapeutic compositions thereof and uses.
Patent CA-2846979-A1 (CA)
Inventor: MALWITZ MARK A
IPC: C07D213/40
Filed: 2012-11-05
Abstract: Disclosed and claimed is a method of inhibiting corrosion of a surface in contact with a corrosive environment encountered in oil and gas operations. The method includes contacting the surface with a composition comprising a quaternary nitrogen-containing corrosion inhibitor having the following general formula. The composition is preferably adherent to standards for environmental friendliness but has equal applicability in formulations that include conventional corrosion inhibitors.
Patent CA-2848175-A1 (CA)
Title: Methods for optimizing a web content proxy server and devices thereof
Inventor: SCODA ENRICO
IPC: H04L29/06
Filed: 2014-04-02
Abstract: A method, non-transitory computer readable medium, and apparatus that includes obtaining content with an original server cookie comprising a name and a value in response to a client request. Whether the value includes one or more of an established set of characters is determined. A new value is generated based on the value of the original server cookie and a URL encoding of the one or more of the established set of characters and any percent characters included in the value of the original server cookie prefixed by a first indicator character, when it is determined that the value includes one or more of the established set of characters. A  web optimized client cookie comprising the new value and the name of the original server cookie concatenated with a domain attribute and path attribute associated with the content is generated. The web optimized client cookie is provided to the client.
Patent CA-2849099-A1 (CA)
Title: Foundation apparatus and method
Inventor: KRONZ WILLIAM MARTIN
IPC: E02D5/74
Filed: 2012-09-21
Abstract: A foundation apparatus comprised of flat plates that is used to support above-ground structures is disclosed. A method of making, using and installing a pile foundation for those applications is also provided. The present invention relates to various flat plate foundation supports that provide a foundation anchor for various ground supported structures. Specifically, the present invention relates to a foundation anchor support that comprises flat longitudinally extending plates that are adapted to be inserted beneath a ground surface.
Patent CA-2852822-A1 (CA)
Inventor: JAMES BRIAN
IPC: F16L57/04
Filed: 2012-10-18
Abstract: A fire insulation precursor material comprising: (i) cement, in an amount of between 10-30% w/w;and (ii) analuminium or magnesium hydroxide, huntite or hydromagnesite in an amount of between 60 90% w/w.
Patent CA-2852937-A1 (CA)
Title: Substituted bicyclic aza-heterocycles and analogues as sirtuin modulators
Inventor: BLUM CHARLES A
IPC: A61P3/00
Filed: 2012-10-19
Abstract: Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided, are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
Patent CA-2853442-A1 (CA)
Inventor: RIBAROV LUBOMIR A
IPC: F25B27/02
Filed: 2014-06-03
Abstract: In at least one embodiment, an energy recovery and regeneration system includes at least one pyroelectric energy recovery module (ERM), a coolant line, a valve and an energy storage module. The at least one pyroelectric ERM generates a voltage in response to realizing a temperature change. The coolant line includes a first end in fluid communication with a coolant source to receive a coolant and a second end disposed adjacent the at least one pyroelectric ERM to deliver the coolant thereto. The valve is interposed between the coolant source and the at least one pyroelectric ERM. The valve modulates the coolant delivered to the at least one pyroelectric ERM to generate the temperate change. The energy storage module is in electrical communication with the pyroelectric ERM to store the voltage generated by the at least one pyroelectric ERM.
Patent CA-2856169-A1 (CA)
Title: Annular barrier system with flow lines
Inventor: HALLUNDBAEK JORGEN
IPC: E21B33/127
Filed: 2012-11-29
Abstract: The present invention relates to an annular barrier system (100) connected with a well head (40) via a well tubular structure (3), comprising a first annular barrier (1) and a second annular barrier (21) to be expanded in an annulus (2) between the well tubular structure and an inside wall (4) of a casing (20) or a borehole (5) downhole for providing zone isolation between a first zone (8) and a second zone (9), each annular barrier comprising a tubular part (6) extending in a longitudinal direction for mounting as part of the well tubular structure, an expandable sleeve (7) surrounding the tubular part and defining a space (13), an opening (11) for letting fluid into the space to expand the sleeve, and a first connection part (15) and a second connection part (16) connecting the expandable sleeve with the tubular part, and wherein the first connection part is arranged nearest to the well head, the system further comprising a flow line (17) fluidly connecting the well head with the opening for supplying fluid to the opening for expanding the expandable sleeve. Furthermore, the present invention relates to a well completion system and method.
Patent CA-2856354-A1 (CA)
Title: Marked coating composition and method for its authentication
Inventor: NOUZILLE ERIC
IPC: C09D7/63
Filed: 2012-11-28
Abstract: This invention relates to the field of authentication of coating compositions such as varnishes, inks and paints, and it is particularly useful in the field of authentication of such coating compositions when applied to substrates like banknotes or other valuable documents. It is particularly directed to a marked coating composition, e.g. an ink, that is marked with a marker (taggant) such as to allow for its authentication, and a method for authenticating such a marked coating composition. The marking is achieved by covalently binding a taggant to a coating composition component, e.g. such used for security documents. The taggant, which is not extractable through usual chemical treatments like washing methods or the use of solvents, can be detected and identified upon thermally induced chemical fragmentation with a PY-GC-MS apparatus. The marked ink or the marked substrate is thus authenticated as belonging to a particularly marked ink, varnish or batch.
Patent CA-2856436-A1 (CA)
Title: Uses of myostatin antagonists
Inventor: DEPAOLI ALEXANDER
IPC: A61K38/08
Filed: 2006-12-06
Abstract: The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-.alpha., and other muscle-related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.
Patent CA-2856979-A1 (CA)
Title: Appareil et procede pour commande de dispositif de fond de trou
Inventor: MACHOCKI KRZYSZTOF
IPC: E21B34/10
Filed: 2012-11-28
Abstract: La présente invention porte sur un appareil pour commande de dispositif de fond de trou dans un puits, qui a un corps ayant une fente de commande et une broche mobile dans la fente. La fente a une première boucle inactive dans laquelle la broche peut réaliser un cycle entre différentes configurations de ralenti, et une seconde boucle active dans laquelle la broche peut se déplacer entre différentes configurations qui correspondent à des configurations active et inactive du dispositif de fond de trou. La broche peut commuter entre les première et seconde boucles, et peut réaliser un cycle entre les différentes configurations sans commuter entre les différentes boucles. La fente peut être disposée sur un piston et le déplacement axial du piston dans le forage peut entraîner le déplacement relatif de la broche et de la fente.
Patent CA-2859831-A1 (CA)
Inventor: LAMBERT PAUL
IPC: E21B25/02
Filed: 2012-01-27
Abstract: A valve assembly for use in an inner tube member of a core barrel head assembly positionable within a drill string of a drilling apparatus. The piston member of the valve assembly is located between a fluid pressure communication port and a fluid flow port to hold the retracting case in an up position and the latches retracted. After an increased fluid pressure has pushed the piston member past the annular element or bushing, the piston member substantially restricts fluid flow through the bushing and allows the retracting case to move to a down position and extend the latches. If the latches are not extended due to an obstruction or misalignment, the retracting case will prevent the piston member from completely passing through the bushing, thus maintaining high fluid pressure due to the flow ports remaining closed, and indicating to the driller that the latches have not properly latched.
Patent CA-2860433-A1 (CA)
Title: System and method for multiple simultaneous group communications in a wireless system
Inventor: REICH JASON ANTHONY
IPC: H04W84/08
Filed: 2007-02-13
Abstract: A system and method enable a wireless device to support simultaneously multiple push-to-talk (PTT) communications and interrupt certain PTT communication with higher priority ones. A user (302) subscribes to multiple PTT communication groups (314, 316) and designates one of the groups as the primary group. The wireless device receives and plays PTT communications from the multiple PTT communication groups and interrupts playing of a PTT communication from a non-primary group if a PTT communication is received from the primary PTT communication group.
Patent CA-2865080-A1 (CA)
Inventor: YOSHIDA TAKAO
IPC: B04B1/20
Filed: 2013-10-11
Abstract: Provided is a centrifugal separator equipped with a separated liquid jet nozzle, capable of reducing energy consumption on the rotational drive of a bowl, and capable of avoiding the problem of the solid contained in the raw liquid being discharged through a jet nozzle to a liquid recovery system, and the problem of the adverse effect being produced on the water content ratio in the discharged solid content when the treatment conditions are changed. A separated liquid jetting device 9, which collects the separated liquid that has overflowed the top of an overflow edge 7a of a dam 7, is attached to a front hub 8 at a position on radially outward of each of the liquid discharge ports 6. The separated liquid jetting device 9 has a separated liquid retention chamber 12 that temporarily retains the collected separated liquid inside thereof, and a jet nozzle 10 that is open in the direction opposite to the rotation direction of the bowl 2 and jets out the liquid located inside the separated liquid retention chamber 12 to the outside is disposed at a side section 9a.
Patent CA-2865158-A1 (CA)
Inventor: IGAWA TOMOYUKI
IPC: C07K16/18
Filed: 2013-02-22
Abstract: Thc present invention provides antigen-binding molecules containing (i) an antigen-binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) an FcyR-binding domain having Fcy RIlb-selective binding activity, and (iii) an FcRn-binding domain having FcRn-binding activity under an acidic pH range condition, and methods of decreasing plasma antigen concentration as compared to before administering the molecule, which include the step of administering the molecule.
Patent CA-2866925-A1 (CA)
Inventor: SCHOOLEY NICHOLAS CLANCY
IPC: F16L25/01
Filed: 2014-10-10
Abstract: Latching mechanisms in multiple embodiments connect clamshell type couplers comprising a pair of arcuate coupling halves joined at a hinge. One embodiment includes a biased catch lever that engages a corresponding latch plate. Another embodiment includes a plurality of latching extensions that engage an opposing latching housing, along with biased locking buttons for selectively locking the mechanism. Another embodiment includes dual rotatable latching arms for interconnecting the coupling halves, each arm having a latching cam for selectively locking the mechanism. Another embodiment includes a rotatable latching arm and a receiving bracket for receiving the latching arm for selectively locking the mechanism.  Another embodiment includes an over center hinge mechanism including three cooperating and rotatable latch plates. Another embodiment includes cooperating cassette mechanisms, each having connector extensions for connecting the cassette mechanisms to one another for selectively locking the mechanism. Methods are also disclosed for selectively locking the latching mechanisms
Patent CA-2868086-A1 (CA)
Title: Method for producing high-purity nickel sulfate
Inventor: IDEGAMI ATSUSHI
IPC: C22B3/44
Filed: 2013-02-13
Abstract: Provided is a method for producing nickel sulfate yielding high-purity nickel sulfate using a method for removing an impurity element to selectively remove Mg from a solution containing Ni. A process for producing nickel sulfate from an acidic solution containing Ni is characterized in that a solution containing Ni is treated sequentially in steps (1) to (3): (1) a carbonation step for adding a carbonating agent to a solution containing Ni, forming the Ni contained in the Ni-containing solution into a precipitate of nickel carbonate or a mixture comprising nickel carbonate and nickel hydroxide, and producing a carbonated slurry comprising this precipitate and carbonated solution; (2) a solid-liquid separation step for separating the carbonated slurry produced in the carbonation step (1) into the precipitate and carbonated solution; and (3) a neutralization step for adding a neutralizing agent to the carbonated solution separated through the solid-liquid separation step (2), and recovering the Ni contained in the carbonated solution as a precipitate of Ni.
Patent CA-2869650-A1 (CA)
Title: Bottle shipping assembly
Inventor: TREMBLAY BENOIT
IPC: B65D81/05
Filed: 2014-11-04
Abstract: The present invention relates to a bottle shipment assembly that can withstand shock and impact during shipping. The assembly can accommodate a wide variety of bottles, uses very little material such as HDPE and PVC, and is easily recyclable. There are three parts to the assembly: a neck portion that locks around the bottle's neck, a base portion that snugly fits around the bottle's bottom, and an exterior box that securely and immovably houses the bottle fitted with the neck portion and base portion. The neck portion has a center portion and two wings that move from inoperable to operable position.  The center portion has with a head-engagement recess that slips over the bottle's neck.  In operable position, the neck portion has a square configuration, and fits snugly inside the exterior box. The base portion also has a square configuration that fits snugly inside the exterior box.
Patent CA-2870096-A1 (CA)
Inventor: WEI HUIJUN
IPC: F04C23/00
Filed: 2012-12-07
Abstract: Provided is a compressor, an air conditioner system comprising the compressor and a heat pump water heater system. The compressor comprises: a low-pressure compression component, a medium-pressure chamber, a low-pressure chamber gas discharge passageway, an enthalpy increasing component, a high-pressure compression component, a medium-pressure gas passageway and a high-pressure chamber gas discharge passageway. The medium-pressure gas passageway comprises a passageway section at the side toward the low-pressure chamber gas discharge passageway and a passageway section at the side toward the high-pressure chamber gas suction passageway, wherein a ratio between a minimum cross sectional area of the passageway section at the side toward the low-pressure chamber gas discharge passageway and a minimum cross sectional area of the passageway section at the side toward the high-pressure chamber gas suction passageway is ranged from 1.4 to 4. In the compressor, the pressure fluctuation and the flow velocity fluctuation of the refrigerant are relatively smaller, which can improve the first-stage gas discharge plumpness and the second-stage gas suction plumpness, and increase the gas replenishment volume, thereby improving the working efficiency and the energy efficiency ratio of the compressor, and reducing the energy consumption.
Patent CA-2871107-A1 (CA)
Title: Method to identify and differentiate background traffic
Inventor: VANNITHAMBY RATH
IPC: H04L12/70
Filed: 2013-05-10
Abstract: Embodiments of a system and method to identify and differentiate background traffic are generally described herein. In some embodiments, a transceiver is arranged to wirelessly transmit and receive packets over a communications network and a processor, coupled to the transceiver, is arranged to provide an indication identifying packets associated with background traffic. The indication identifying packets associated with background traffic includes a bit in a header of a packet, wherein the bit is set in a first state to indicate the packet is associated with background traffic and the bit is set in a second state to indicate the packet is associated with active traffic, or an identification of a port number and a protocol type associated with background traffic. The processor is further arranged to provide an indication for differentiating background traffic.
Patent CA-2879623-A1 (CA)
Inventor: GUILLEMONT JEROME EMILE GEORGES
IPC: C07D401/06
Filed: 2013-08-09
Abstract: The present invention is related to compounds of formula (I) that may inhibit the activity of the FabI  enzyme, and which are useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
Patent CA-2880652-A1 (CA)
Inventor: BEZANSON ANDRE B
IPC: G01S15/89
Filed: 2013-08-09
Abstract: To address limitations of conventional transducers, a phased array transducer is provided with a form factor suitable for packaging into, e.g., an endoscope. A method of manufacture of small packaging transducers is also provided, whereby the overall package size is reduced by electrically connecting signal wires to array electrodes at an angle approximately normal to the array surface, thus largely eliminating the bend radius requirements of conventional printed circuit boards or flex circuits.
Patent CA-2882229-A1 (CA)
Inventor: HOGDAHL STEFAN
IPC: A61M5/46
Filed: 2013-08-07
Abstract: The present invention relates to a medicament injection device (100) arranged to receive a replaceable container subassembly (103) The medicament injection device (100) comprises a front housing (102) and a rear housing (101) releasably connectable to each other. A reloadable drive mechanism (108) is accommodated in the rear housing (101) for acting on the plunger (14) of a replaceable container subassembly (103) for expelling medicament. A needle hider front is slidably arranged within the front housing. A needle shield remover (109) is arranged to connect with a needle shield of the replaceable container subassembly, wherein the needle shield remover is arranged to be removably inserted into a proximal end of the front housing through the needle hider front. The needle shield remover is adapted to be used to interact with the reloadable drive mechanism accommodated in the rear housing such that a user can reload the drive mechanism.
Patent CA-2882485-A1 (CA)
Title: Appareil, systeme et methode de soutien d'un assemblage d'aile
Inventor: DESJARDIEN MATTHEW RAY
IPC: B23Q1/25
Filed: 2015-02-19
Abstract: Un procédé et un appareil permettant de supporter une structure. Lappareil peut comprendre un support, une structure déquilibrage de charge associée au support et un ensemble de dispositifs de raccordement associés à la structure déquilibrage de charge. Lensemble de dispositifs de raccordement peut être configuré pour relier à la structure un ensemble de points de contrôle. Chacun des dispositifs de raccordement de lensemble peut être configuré pour commander indépendamment un emplacement dun point de contrôle correspondant dans lensemble de points de commande.
Patent CA-2883906-A1 (CA)
Inventor: BLOUGH CHAD ERIC
IPC: A61F7/02
Filed: 2013-09-04
Abstract: The present disclosure provides a prefilled wrap, such as a prefilled poultice wrap, for applying to the body of a human or animal. The prefilled wrap includes a matrix defining a plurality of pockets therein. The prefilled wrap also includes a dry ingredient formulation contained in each of the plurality of pockets. The present disclosure also provides a prefilled wrap system for applying to the body of a human or animal. The prefilled wrap system includes an outer casing configured to wrap around a portion of the body of the human or animal. The prefilled wrap system also includes a prefilled wrap removably received in the outer casing. The outer casing is configured to hold the prefilled wrap against the body of the human or animal. Related methods of manufacturing the prefilled wrap, applying the prefilled wrap, and applying the prefilled wrap system are also disclosed.
Patent CA-2887170-A1 (CA)
Inventor: POWELL JOSEPH BROUN
IPC: C10G3/00
Filed: 2013-10-03
Abstract: Embodiments of the invention provide for a process, system, and composition for lignocellulosic biomass conversion that includes a supported metal catalyst having a avoid fraction in the range of from 45 % to 95 % and a surface area in the range of 10 m2/g to 1000 m2/g containing (a) Mo or W, and (b) Co, Ni or any mixture thereof.
Patent CA-2888131-A1 (CA)
Inventor: POSARELLI ROBERTO
IPC: B44C1/16
Filed: 2013-10-23
Abstract: The present invention concerns the field of graphic apparatuses and in particular its object is an apparatus and a relative method for the so-called "weeding" of plastic or paper films having or more self- adhesive, double sided adhesive or electrostatic layers coupled with a support liner treated with a non-stick agent. The apparatus comprises analysis and cutting means adapted to map and execute weeding assisting cuts.