baber/WOPTO huggingface dataset:
Patent NZ-227400-A (NZ)
Title: Thiol-ketone and thiol-aldehyde derivatives, intermediates thereof and pharmaceutical compositions
Inventor: MARKWELL ROGER EDWARD
IPC: A61K31/22
Filed: 1988-12-20
Abstract: Novel compounds of the formula (I), a process for their preparation and their use as collagenase inhibitors are described: <CHEM>  in which,R1 is hydrogen, alkyl, or optionally substituted aryl;  R2 is hydrogen, or acyl such as   - @-alkyl or - @ - Z where Z is optionally substituted aryl;  R3 is C3-6 alkyl; R4 is hydrogen, alkyl, -CH2-R10 where R10 is optionally substituted phenyl or heteroaryl, or a group <CHEM> where R11 is hydrogen, alkyl, or -CH2-Ph where Ph is optionally substituted phenyl, and R12 is hydrogen or alkyl; and  R5 is hydrogen, alkyl, or a group <CHEM> where R13 is hydrogen, or alkyl, and R14 is hydroxy, alkoxy, or -NR6R7, where each of R6 and R7 is hydrogen or alkyl, or R6 and R7 together with the nitrogen atom to which they are bonded form a 5-, 6- or 7-membered ring with an optional oxygen or sulphur atom in the ring or an optional further nitrogen atom optionally substituted by alkyl.
Patent NZ-234297-A (NZ)
Title: Mutant enzyme less stable than wild type (especially an alpha-amylase), microorganism, gene, vector, and a process for making dough or bread
Inventor: VAN EIJK JAN HENRICUS
IPC: C12N1/21
Filed: 1990-06-28
Abstract: A mutant enzyme is provided which exhibits reduced stability under industrial application conditions. As an example mutant bacterial alpha -amylase is provided which has reduced thermostability during baking conditions. This modified  alpha -amylase can be suitably used for improving both loaf volume and crumb softness of bread products without causing any danger of overdextrination.
Patent NZ-237283-A (NZ)
Title: Three-dimensional non-woven fabric for facing layer of fibrous mat article
Inventor: BOULANGER ROGER
IPC: D04H18/04
Filed: 1991-03-01
Abstract: A three-dimensional non-woven fabric with a thermally activated adhesive surface well suited for use as a facing fabric for covering a fibrous mat. The fabric comprises two adjoining fiber layers, namely an adhesive layer including bond-forming fibers fusible at a predetermined temperature and a facing layer of fibers having a considerably higher melting temperature than the bond-forming fibers. The fibers of both layers are mechanically engaged one with another and are arranged flat-wise in bundles interconnected at junctures by protuberant fiber packings disposed in a staggered relationship throughout the fabric. Bond-forming fibers are concentrated in the apex portions of the fiber packings to form the thermally activated adhesive surface. The invention also extends to a process for manufacturing the three-dimensional non-woven fabric, based on the so-called "rosebud" technique for producing foraminous webs. The invention further comprehends a molded fibrous mat article with a non-woven fabric facing layer, and a method for producing the article.
Patent NZ-242774-A (NZ)
Title: Substituted imidazo[2,1-b][3]benzazepine derivatives, preparation and pharmaceutical compositions thereof
Inventor: JANSSENS FRANS EDUARD
IPC: A61K33/06
Filed: 1992-05-15
Abstract: The present invention is concerned with novel imidazo[2,1-b][3]benzazepines of formula <CHEM> the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each of the dotted lines independently represents an optional bond; R<1> represents hydrogen, halo, C1-4alkyl or C1-4alkyloxy; R<2> represents hydrogen, halo, C1-4alkyl or C1-4alkyloxy; R<3> represents hydrogen, C1-4alkyl, ethenyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, C1-4alkyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl or hydroxycarbonyl; R<4> represents hydrogen, C1-4alkyl, hydroxyC1-4alkyl, phenyl or halo; R<5> represents hydrogen, C1-4alkyl or halo; L represents hydrogen; C1-6alkyl; C1-6alkyl substituted with one substituent selected from the group consisting of hydroxy, halo, C1-4alkyloxy, hydroxycarbonyl, C1-4alkyloxycarbonyl, C1-4alkyloxycarbonyl-C1-4alkyloxy, hydroxycarbonylC1-4alkyloxy, C1-4alkyloxycarbonylamino, C1-4alkylaminocarbonyl, C1-4alkylaminocarbonylamino, C1-4alkylaminothiocarbonylamino, aryl, aryloxy and arylcarbonyl; C1-6alkyl substituted with both hydroxy and aryloxy; C3-6alkenyl; C3-6alkenyl substituted with aryl; or, L represents a radical of formula -Alk-Y-Het<1> (a-1), -Alk-NH-CO-Het<2> (a-2) or -Alk-Het<3> (a-3); provided that 6,11-dihydro-11-(4-piperidinylidene)-5H-imidazo[2,1-b][3]benzazepine is ecxluded, which are useful antiallergic compounds. Compositions comprising said compounds, methods of using and processes for preparing the same.
Patent NZ-253070-A (NZ)
Title: Ovicidal compositions and method of combatting insect eggs
Inventor: HAFEZ AYAD
IPC: A01N47/40
Filed: 1993-05-21
Abstract: A method has been found for protecting a crop by killing eggs of insects, or insects at the egg stage wherein the insects are detrimental to the crop. This method comprises applying to a locus where the eggs of insects are located or are expected to be located an effective amount of a compound of formula (I), or a salt thereof, R1-X-N(R2)-C(R3)=Z-R4 (I) wherein R1 represents an optionally substituted aromatic hetero ring containing nitrogen atom; X represents an optionally substituted alkylene or alkylidene; R2 and R3 represent hydrogen or optionally substituted alkyl; R4 represents a cyano or a nitro, and Z represents CH or N. The insect eggs which can be killed include tobacco budworms, pyrethroid resistant tobacco budworm, Mexican bean beetle or Colorado potato beetle.
Patent NZ-268649-A (NZ)
Title: Butt joining of fibre reinforced thermoplastic pipes: pipe ends upset so that inner layer of weld is fibre free
Inventor: GREIG JOHN MARTYN
IPC: B29C65/00
Filed: 1994-07-19
Abstract: PCT No. PCT/GB94/01566 Sec. 371 Date Mar. 12, 1996 Sec. 102(e) Date Mar. 12, 1996 PCT Filed Jul. 19, 1994 PCT Pub. No. WO95/03162 PCT Pub. Date Feb. 2, 1995An electrofusion coupler is slid over one of two thermoplastic pipes, each having a layer or layers of reinforcing fibers between the center of the wall of the pipe and the outside surface of the pipe. The end surfaces are trimmed in a butt fusion machine and the resulting end surfaces are forced against a heater plate. The plate is removed and the end surfaces are forced together. Internal and external beads involving inward and outward flow of material result, the outward flow ensures that there is at the welded joint an inner layer which is free from reinforcement fibers. The external bead is removed and the coupler is slid over the butt fused welded joint and energized to cause it to become fusion welded to the outside of the pipe.
Patent NZ-270685-A (NZ)
Title: Imidazodiazepine derivatives and their use in medicaments
Inventor: GODEL THIERRY
IPC: A61P21/02
Filed: 1995-03-10
Abstract: Aminomethyl-substd. oxadiazolyl-imidazodiazepines of formula (I) and their addn salts are new: A and C atoms  alpha  and  beta form a gp of formula e.g. (A<1>):Q = a gp. of formula e.g. (Q<1>):R<1>, R<2> = H; lower alkyl,etc.;or NR<1>R<2> = 5-8 membered heterocycle opt. contg. a further hetero atom or carrying a fused benzene ring; R<3> = H and R<4> = lower alkyl; or R<3>+R<6> = H; halo;etc.; and C atom gamma  has the S configuration when R<3> is other than H.
Patent NZ-273300-A (NZ)
Title: Removing excess thread from chain of tea bags: thread cut and severed end lifted from web so that other end can be cut
Inventor: BAILEY THOMAS WILLIAM
IPC: B65B29/04
Filed: 1994-08-16
Abstract: A web (W) of sheet material intended to form individual tagged packets has surplus portions of a thread (S) extending along its length removed while the web is being advanced. After severing one end of each unwanted thread portion with a rotary cutter (2), the severed end is lifted by a wiper (10), and the lifted end is held away from the web by suction means (20) while it is detached by shearing means (22). The suction means (20) then remove the detached thread portion.
Patent NZ-287894-A (NZ)
Title: Preparation of pearls of prolonged or rapid release profile pharmaceutically active ingredient (typically ketoprofen) containing the ingredient with an unspecified melting point
Inventor: DELEUIL MICHEL
IPC: A61J3/06
Filed: 1995-06-01
Abstract: Pearls of an active principle exhibiting an indefinite crystallization point, wherein said pearls exhibit a prolonged, immediate or combination release profiles, are made by melting the active principle and a crystallization excipient to create a molten mixture; introducing the mixture into feed receptacles of a prilling tower; passing the mixture through a nozzle which is vibrated to form pearls; and allowing the pearls to fall in the tower countercurrentwise to cold air, where the tower is provided with a fluidized bed proximate the bottom of the tower and the temperature conditions of the said fluidized bed are maintained depending on the release profile desired.
Patent NZ-314442-A (NZ)
Title: Extended release formulation comprising venlafaxine hydrochloride, film coating composition
Inventor: SHERMAN DEBORAH MARIE
IPC: A61K9/00
Filed: 1997-03-19
Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets.
Patent NZ-322836-A (NZ)
Title: A cement contains calcium carbonate, caustic magnesium oxide, and a source of carbonation during setting
Inventor: RECHICHI DINO
IPC: C04B9/00
Filed: 1996-12-03
Abstract: A dry powdered flowable cement composition contains calcium carbonate and a partially decarbonated magnesium carbonate. A slurry of the composition will set hard with various organic fillers including waste products and toxic waste. The composition can be slurried with contaminated water such as sea water, mineral laden ground water and muddy water. A high percentage of filler can be added while still having an acceptable set.
Patent NZ-336833-A (NZ)
Title: Subscriber identity module for mobile phone, with two data transfer devices
Inventor: LEHMUS MARJA-LEENA
IPC: G06Q20/00
Filed: 1998-01-27
Abstract: A subscriber identity module (SIM) for a mobile phone includes two data transfer devices RP1, RP2, connected to a microprocessor 1.  One of the data transfer devices, RP! Is used for data transfer between the mobile phone and the SIM, while the other, RP2 is used for data transfer between the SIM to an external device.
Patent NZ-502481-A (NZ)
Title: Method of applying water absorbing polymers for agricultural water retention and flow enhancement mixture
Inventor: SALESTROM RONALD D
IPC: C09K17/16
Filed: 1998-07-16
Abstract: A technique is disclosed of applying selected chemicals for increasing agricultural water retention and minimizing erosion. The technique applies water absorbent polymers (10) into the top layer (15) of the field. These polymers create a water barrier within the soil. Subsequently, a linear polymer such as polyacrylamide is applied to the soil's surface to minimize erosion during irrigation and precipitation. The water absorbent polymers (10) assist in the thorough application of the linear polymer as the linear polymer is maintained at the surface area and prevented from leeching away.
Patent NZ-511746-A (NZ)
Title: Antenna for use of portable wireless communication system
Inventor: CHANG EUNG-SOON
IPC: H01Q1/10
Filed: 1999-11-30
Abstract: An antenna for use in a portable wireless communication system in which said antenna has a single unit configuration so as to function as a helical antenna when retracted and as a rod antenna when extracted, and a spring arranged in said helical antenna formed from a leaf spring rolled to have a thickness of psi 0.5, and a C-ring to be coupled to a lower interior of said spring shaped as a circle having at side surfaces thereof a plurality of resilient plates inserted into a supporting member and contracted so that an antenna may be resiliently fixed when extracted or retracted.
Patent NZ-512326-A (NZ)
Title: Fusion proteins containing at least two receptor binding domains and a multimer-forming component
Inventor: YANCOPOULOS GEORGE D
IPC: A61P25/28
Filed: 1999-12-23
Abstract: A nucleic acid molecule encoding a fusion polypeptide which comprises a first subunit comprising at least one copy of the receptor binding domain of a ligand, the first subunit being fused to the N-terminal end of a multimerizing component, which comprises an immunoglobulin derived domain, and has a second subunit fused to its C- terminal end, the second subunit comprising at least one copy of the receptor binding domain of a ligand. Also covered are expression vectors comprising said nucleic acid molecule and methods of producing the fusion polypeptide by expressing the vector in a host system.
Patent NZ-514372-A (NZ)
Title: Flexible organic electronic device with improved resistance to oxygen and moisture degradation
Inventor: CARCIA PETER FRANCIS
IPC: H01L21/00
Filed: 2000-04-27
Abstract: Flexible composite barrier structures are used to improve the resistance to oxygen and moisture degradation of an organic electronic device including at least one active layer comprising an organic material.
Patent NZ-517439-A (NZ)
Title: Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof
Inventor: FUJIKURA HIDEKI
IPC: A61P3/04
Filed: 2000-08-24
Abstract: Glucopyranosyloxypyrazole derivatives  represented  by general  formula  (I),  which have an effect  of  inhibiting human  SGLT2  activity  and  are useful  as  preventives  or remedies   for  diabetes,  complications  of   diabetes   or obesity.  In  formula (i), R1 represents hydrogen  or  lower alkyl;  one of Q1 and T1 represents a group of formula  (A), while  the other represents lower alkyl or halogenated lower alkyl;  and  R2  represents  hydrogen,  lower  alkyl,  lower alkoxy,   lower  alkylthio,  halogenated  lower   alkyl   or halogeno.
Patent NZ-518898-A (NZ)
Title: Intaglio printing inks using linseed fatty acid as the autoxidisable polyester resin
Inventor: GHIOGHIU ANA
IPC: C09D11/105
Filed: 2000-11-22
Abstract: An Intaglio printing ink in which the binder is an autoxidisable polyester resin with fatty acid content between 40 and 60% by weight and the preferred fatty acid is linseed fatty acid.  The fatty acid has at least 25% of its chain as linolenic acid.   The printing ink includes solvents and pigments and can be cured under UV irradiation to produce useful printed material on polymer substrate.
Patent NZ-523181-A (NZ)
Title: A conductive wire line and method of making a conductive downhole wire line system
Inventor: MOORE BOYD B
IPC: H01B17/58
Filed: 2000-02-11
Abstract: A conductive wire line (10) including a small diameter tubing (34) having an outer diameter between 1/8" and 1/2" and one or more optical fibres (36) extending through the inner diameter of the tubing (34).  The optical fibres (36) are in a helical configuration so that they have a length longer than the tubing (34) in which they extend
Patent NZ-524323-A (NZ)
Title: A dental contact matrix system
Inventor: MCDONALD SIMON PAUL
IPC: A61C5/04
Filed: 2003-02-18
Abstract: A wedge for use with a dental contact matrix system is described for the placement of dental fillings. The wedge comprises a one piece member of elastic material having an elongated narrow section and an elongated tapered section with a triangular cross section. The elongated narrow section extending directly or indirectly from the narrow end of said tapered section. A wedge having two elongated tapered sections is also described. (62) Divided out of 515528
Patent NZ-525895-A (NZ)
Title: Use of short messaging (SMS) for sending encoded survey responses to a data analysis system, which decodes and analyses the message
Inventor: SMITH BRYAN LESLIE
IPC: H04M11/08
Filed: 2003-05-15
Abstract: A system is for processing data prompted by answering of more than one question in a messaging system environment. A text or SMS message containing the answers in encoded form is transmitted to a defined destination and at the destination the answers are presented to a data analysis system for decoding and recording the separate answers. The data analysis system can detect when at least some of the answers are invalid.
Patent NZ-531560-A (NZ)
Title: Mixer circuit with image frequency rejection, in particular for an RF receiver with zero or low intermediate frequency
Inventor: JOVENIN FABRICE
IPC: H04B1/30
Filed: 2002-07-19
Abstract: A mixer circuit with image frequency rejection includes a quadrature phase splitter 30 with an input which is connected to the input (Fi) of the mixer circuit and two outputs which deliver respectively two phase quadrature signals which are applied respectively to two simple mixers 31, 32. Two inputs of a quadrature phase and frequency splitter 33 having a frequency division ratio of DIV are connected respectively to the respective outputs of the two simple mixers 31, 32 and a further two inputs receive respectively quadrature signals derived from the output F0 of the mixer. The mixer is useful in GHz radio receiver of zero of quasi-zero intermediate frequency to supply baseband quadrature signals to the demodulator.
Patent NZ-532633-A (NZ)
Title: Haemodynamic monitoring
Inventor: WARRING-DAVIES KEN
IPC: A61B5/022
Filed: 2002-11-13
Abstract: Mean Pulmonary Arterial Pressure (MPAP), Mean Pulmonary Capillary Wedge Pressure (MPCWP) and Cardiac Index are all determinable (in a method or employing apparatus) from Central Venous Pressure (CVP), Mean Arterial Pressure (MAP), Heart Rate (HR), and Core Body Temperature (T) from the following relationships: MPAP = (a x MAP) + CVP (for MAP < 58), or Va; MPAP = (a x MPAP) + CVP - (10 x INT[(MAX {MAP-109), (CVP-7),0})/10]) for MAP > 58); Vb; MPCWP = (b X MPAP) + CVP - (10 X INT [CVP-7/10]; and VI; CI = K (T.CVP)/ HR<2>, VII; where a and b are about 0.15; MAX (x, y, z) = largest of the three terms x, y, and z; INT [x] = integer part of x; MAP and CVP is measured in mmHg; T in Celsius and HR in counts per minute; CI is litres per square metre per minute; and K is a variable constant whose value is between 0 and 1000 depending on the values of CVP and HR.
Patent NZ-535081-A (NZ)
Title: Combinations comprising epothilone derivatives and alkylating agents
Inventor: ANDERSON JUDITH ROSE
IPC: A61K31/425
Filed: 2003-03-07
Abstract: Disclosed is a pharmaceutical combination which comprises (a) an imidazotetrazinone (which may be selected from temozolomide and mitozolomide) and (b) an epothilone derivative of formula (I) wherein A represents O or NRN, wherein RN is hydrogen or lower alkyl, R is hydrogen or lower alkyl, and Z is O or a bond, in which the active ingredients (a) and (b) are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier; for simultaneous, separate or sequential use. These pharmaceutical combinations can be useful for the treatment of a proliferative disease, especially a tumor disease.
Patent NZ-537523-A (NZ)
Title: Pyrrolo-triazine compounds that inhibit the tyrosine kinase activity of growth factor receptors
Inventor: BHIDE RAJEEV S
IPC: A61P29/00
Filed: 2003-07-18
Abstract: Pyrrolo-triazine compounds such as [(1R), 2S]-2-Aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f] [1,2,4] triazin-6-yloxy]-1-methylethyl ester and others particularly described in the specification, and pharmaceutically acceptable salts thereof are disclosed. These compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. These compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Patent NZ-538768-A (NZ)
Title: Orthopoxvirus vector such as vaccinia wherein the nucleotide sequence encoding A52R is inactivated by mutation or insertion of foreign DNA
Inventor: O'NEILL LUKE ANTHONY JOHN
IPC: A61K38/095
Filed: 2003-09-05
Abstract: An orthopoxvirus vector such as vaccinia wherein the nucleotide sequence encoding A52R is inactivated by mutation or insertion of foreign DNA. Also disclosed is a viral protein comprising amino acid SEQ ID NO:2 and the use of a vaccinia virus comprising the amino acid sequence in the preparation of a medicament for the modulation and/or inhibition of IL1R/TLR superfamily signalling.
Patent NZ-541075-A (NZ)
Title: Pharmacological vitreolysis
Inventor: PAKOLA STEVE
IPC: A61K38/48
Filed: 2003-12-05
Abstract: Disclosed is the use of a composition comprising a truncated form of plasmin comprising a catalytic domain of plasmin (TPCD) in the preparation of a medicament for preventing a disorder, or a complication of a disorder, of an eye of a subject comprising contacting a vitreous and/or aqueous humor). TPCDs include, but are not limited to, miniplasmin, microplasmin and derivatives and variants thereof. The methods of the composition can be used to reduce the viscosity of the vitreous, liquefy the vitreous, induce posterior vitreous detachment, reduce hemorrhagic blood from the eye, clear or reduce materials toxic to the eye, clear or reduce intraocular foreign substances from the eye, increase diffusion of a composition administered to an eye, reduce extraretinal neovascularization and any combinations thereof. The method can be used in the absence of, or as an adjunct to, vitrectomy.
Patent NZ-546457-A (NZ)
Title: Methods and apparatus for the systemic control of ventilatory support in the presence of respiratory insufficiency
Inventor: BASSIN DAVID JOHN
IPC: A61M16/00
Filed: 2004-11-25
Abstract: An apparatus for providing ventilatory assistance to a patient is provided. Two error signals are derived, each of which is a function of the same target value and a respective one of two patient ventilation measures. The two patient ventilation measures have respective relatively fast and relatively slow speeds of response. Two control responses are also derived from the two error signals and the two control responses are combined to produce an overall control response. The ventilator is responsive to the overall control response. The ventilator response controls the pressure of air delivered to the patient.
Patent NZ-550739-A (NZ)
Title: Polymeric coupling agents and pharmaceutically-active polymers and therefrom
Inventor: SANTERRE PAUL J
IPC: A61K31/785
Filed: 2005-05-13
Abstract: Provided is a pharmaceutically-active polymeric compound of the general formula (I), Y-[Yn-LINK B-X]m-LINK B (I) wherein (i) X is a coupled biological coupling agent of the general formula (II): Bio-LINK A-Bio (II), wherein Bio comprises a radical of a biologically active agent linked to LINK A through a hydrolysable covalent bond; and LINK A is a coupled linear first segment having a molecular weight of 60 to 2000 Daltons linked to each of said Bio radicals; (ii) Y is LINK B-OLIGO; wherein (a) LINK B is a coupled second segment having a molecular weight of 60 to 2000 Daltons linking one OLIGO to another OLIGO and an OLIGO to X or precursor thereof; and (b) OLIGO is a polymer segment having a molecular weight of less than 5,000 Daltons and comprising less than 100 monomeric repeating units; (iii) m is 1-40 ; and (iv) n is selected from 2 - 50, wherein said compound is synthesized by step growth polymerization of PBio-LINK A-PBio with a prepolymer of formula Yn-LINK B, wherein each PBio bears a similar functional group for polymerization with said prepolymer, and wherein said compound comprises a polyurethane, polyamide, polyurea, or polysulfonamide.