baber/WOPTO huggingface dataset:
Patent PT-2288619-E (PT)
Title: Cyclized non-native synthetic peptide and complex of peptides comprising said cyclized peptide, intended to induce and to characterize the prevention or treatment of conditions in mammals
Inventor: VICENS SERGE
IPC: A61K39/08
Filed: 2009-06-18
Abstract: Non-native synthetic peptide cyclized by means of a disulphide bridge, characterized by the amino acid sequence (E34P) that follows (SEQ ID No. 1): E-D-E-H-K-G-K-Y-C-R-L-G-N-D-C-R-T-T-E-P-T-T-T-A-T-P-R-G-T-P-T-P-A-P and a complex of non-native synthetic peptides that is intended to induce and characterize the prevention and/or treatment of conditions in mammals, the protective immunity of which depends on the stimulation of Th1 type lymphocytes, and, in particular, on a state of delayed hyperstimulation, containing: —said peptide (E34P), —the following sequence (A16E) of 16 amino acids (SEQ ID No. 2) or derivatives (structural analogues) thereof: A-A-R-C-A-R-C-R-E-G-Y-S-L-T-D-E —the following sequence (A16G) of 16 amino acids (SEQ ID No. 3) or derivatives (structural analogues) thereof: A-A-S-S-T-P-S-P-G-S-G-C-E-V-D-G, —and an adjuvant which preferably induces a cell-mediated response.
Patent PT-594019-E (PT)
Inventor: KAZDA STANISLAV
IPC: C07D213/79
Filed: 1993-10-11
Abstract: Trisubstituted biphenyls of the general formula <IMAGE>  in which     R<1> stands for a carboxyl radical, or  for a C1-C8-alkoxycarbonyl radical,   R<2> stands for straight-chain or branched C1-C8-alkyl, R<3> stands for halogen, hydroxyl, cyano, C1-C6-alkoxy, straight-chain or branched C1-C8-alkyl, trifluoromethyl, trifluoromethoxy, carboxamido, carboxyl, C1-C8-alkoxycarbonyl or nitro,  and   R<4> stands for a carboxyl radical, or  for tetrazolyl,  and their salts. The trisubstituted biphenyls can be employed as active ingredients in medicaments, for example as angiotensin II antagonists.
Patent PT-707077-E (PT)
Inventor: EKEZE TOBIAS E
IPC: C12Q1/6806
Filed: 1995-09-14
Abstract: Nucleic acids can be made available for amplification or other treatment after lysis by contacting the lysate with specific weakly basic polymers to form a precipitate with the nucleic acids at acidic pH. After removing non-precipitated materials, the pH is then made basic, thereby releasing the nucleic acids from the polymer. This method for preparing specimen samples is simple and quite rapid, and the released nucleic acids can be further treated in hybridization assays or amplification procedures. The weakly basic polymers are water-soluble and cationic at acidic pH, but neutral in charge at basic pH.
Patent PT-765389-E (PT)
Inventor: YOUNG KATHLEEN H
IPC: C12Q1/6897
Filed: 1995-05-31
Abstract: This invention relates to novel modified host cells which express heterologous fused proteins and methods of screening for test samples having peptide-binding activity; wherein the modified host cell comprises: (a) a gene sequence encoding a heterologous fusion protein; said fusion protein comprising a first peptide of a peptide binding pair, or segment of said first peptide, which is joined to either a DNA binding domain or its corresponding transcriptional activation domain of a transcriptional activation protein; (b) a gene sequence encoding a heterologous fusion protein, said fusion protein comprising a second peptide of the peptide binding pair in (a), or a segment thereof, fused to either a DNA binding domain or its corresponding transcriptional activation domain, whichever one is not employed in (a); (c) a reporter gene operatively associated with the transcriptional activation protein, or a portion thereof; (d) optionally, a deletion or mutation in the chromosomal DNA of the host cell for the transcriptional activation protein if present in the selected host cell.
Patent PT-781101-E (PT)
Inventor: DITTRICH DAVID JOHN
IPC: A24D1/22
Filed: 1995-09-06
Abstract: The invention relates to a smoking article having a high proportion of non-combustible, inorganic material and a relatively low level of visible sidestream. The smoking article comprises a substantially non-combustible, wrapper which extends along the full length of the smoking material rod and enwraps a combustible fuel source and aerosol generating means, both of which extend substantially along the full length of the smoking material rod. Various suitable fuel source systems and aerosol generating systems are described. The article has a visible burn line which advances along the article and produces an ash which can be removed by the smoker in the normal way. <IMAGE>
Patent PT-748326-E (PT)
Inventor: SPAGNOL MICHEL
IPC: C07F9/02
Filed: 1995-12-22
Abstract: The present invention relates to optically active diphosphines. It is also targeted at their preparation according to a process for the resolution of the racemic mixture of the said phosphines to optically active isomers. The subject of the invention is new optically active bis[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] diphosphines and a process for resolving the racemic bis[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] mixture which comprises reacting it with a palladium or platinum complex as chiral auxiliary in an organic solvent, thus forming diastereoisomer complexes, and then resolving the said optically pure complexes. The invention also relates to new optically active metal complexes comprising the said phosphines and to their use in a process for the preparation of optically active carboxylic acids and/or derivatives according to a process for the hydrogenation of  alpha , beta -unsaturated carboxylic acids and/or derivatives.
Patent PT-751103-E (PT)
Inventor: GOODMAN HOWARD
IPC: C04B33/28
Filed: 1996-06-12
Abstract: A clay composition for use in slip casting comprises:     a) a major amount of at least one kandite clay; b) a minor amount of an organic additive comprising at least one water-soluble compound having a plurality of basic groups;  and is characterised by also including   c) a minor amount of at least one non-calcined smectite clay.   Also disclosed is the use of the clay composition together with a slip medium, eg. comprising water, to form a slip coating composition and the use of such a composition in producing slip cast ceramic articles.
Patent PT-771566-E (PT)
Inventor: JOSE ALONSO FERNANDEZ MARIA
IPC: A61K9/107
Filed: 1996-05-24
Abstract: Stabilization of colloidals systems through the formation of ionic lipid-polisaccharide complexes. There is disclosed a process for the preparation of colloidal systems which includes the incorporation of a water soluble and positively charged amino polysaccharide and a negatively charged phospholipid. The colloidal systems (which comprise polymer nanoparticles, nanocapsules and nano-emulsions) are stabilized through the formation of a ionic complex, at the interface, comprised of the aminopolysaccharide and the phospholipid. The colloidal systems are characterized in that they have a particle size lower than 1  mu m, a electric positive charge and an exeptional stability during storage. They are lyophilizable so that they can be dry stored and redispersed subsequently while maintaining the original characteristics of the system. They are useful as pharmaceutical forms for the oral, transdermic, topical, ocular, nasal and vaginal administration of medicaments. They are also useful as forms for cosmetic use.
Patent PT-849760-E (PT)
Inventor: SCHLEGEL TORSTEN
IPC: H01H71/10
Filed: 1997-12-17
Abstract: The invention relates to a knob connection for a multipolar switching device that is composed of single-pole switching devices, the single-polar switching devices of which have thermoplastic operating knobs, arranged juxtaposed and pivoting around a common axis, and connected by means of a rigid grip strip covering the individual operating knobs. The operating knobs (1) have, on the narrow side facing upwards, a slit-like recess (1.3) closed on both front sides (1.4) and running in axial direction. The recess has undercuts (1.6), facing both side faces, in a plane perpendicular to the axis direction (2.1'). The grip strip (3), which is also made of thermoplast, has peg-shaped protruding elements (3.1), across the width of the single-pole switching devices and corresponding to their number, which, with serrated projections (3.2) adapted to the undercuts (1.6), can be later, elastically, as well as captively locked twist-proof into the recesses (1.3), while lengthwise along the grip strip (3), between the protruding elements (3.1) and the recesses (1.3), there is sufficient play to compensate for tolerances and material contraction.
Patent PT-863196-E (PT)
Inventor: ITALIA PAOLO
IPC: C10C3/04
Filed: 1998-03-05
Abstract: Process for the preparation of bitumens for road use, characterized in that it comprises the oxidation of a composition consisting of (a) a bituminous component (I) having a content of asphaltenes of between 10 and 50%, a content of aromatics of between 10 and 50% by weight, and a penetration at 25 DEG C of from 1 to 50 dmm, and (b) an aromatic component (II) essentially without asphaltenes and having a content of aromatics of from 80 to 95%, and a viscosity at 60 DEG C of from 100 to 1000 cSt; the weight ratio between the aromatic component (II) and the bituminous component (I) being from 10:90 to 50:50.
Patent PT-1096943-E (PT)
Inventor: PERO RONALD W
IPC: A61P35/00
Filed: 1998-07-13
Abstract: The present invention is directed to a method of preparation and the composition of a water soluble extract of the plant species Uncaria. The present invention is also directed to the pharmaceutical use of the composition for the enhancement of the immune, anti-inflammatory, anti-tumor and DNA repair processes of warm blooded animals. The present preparation of the water soluble extract of the plant species Uncaria results in the depletion of many of the ingredients which lead to various toxic side effects associated with other extracts or compositions derived from Uncaria. Also, the present preparation leads to the depletion of many of the active ingredients commonly associated with other extracts and compositions of the plant species Uncaria. Therefore, the present invention teaches that the hot water extraction of the crude plant parts of Uncaria and the subsequent dialysis of the solubilized products yields a low molecular weight composition which maintains a high degree of the anti-tumor, inflammatory and immune stimulatory activities associated with the crude plant parts.
Patent PT-1058535-E (PT)
Inventor: GALLI GIOVANNA
IPC: A61K8/04
Filed: 1998-05-20
Abstract: A dental composition for the treatment of dentinal hypersensitivity and in particular for the desensitization of exposed dentin, the desensitizing treatment of deep cavities, the desensitizing treatment when replacing dental layers, the stumps desensitizing treatment before placing dental prosthesis. The composition can be used as a solution or as a gel. In the first case two distinct liquid solutions for use successively on the exposed dentin are provided for. In the second case two distinct gel compounds spread successively on the exposed dentin are provided for. The first solution or the first gel compound comprises preferably three soluble potassium salts, whereas the second solution or the second gel compound comprises a calcium salt and a soluble strontium salt. In a preferred composition two solutions are provided for of which the first has solutes comprising potassium phosphate, potassium carbonate and potassium fluoride, and the second solution has solutes comprising calcium chloride and strontium chloride. For the gel composition, which may be used as toothpaste, two distinct gel compounds are provided, the first having solutes comprising potassium phosphate, potassium carbonate and potassium fluoride and the second gel compound having solutes comprising calcium chloride and strontium chloride.
Patent PT-1039887-E (PT)
Inventor: STOGNIEW MARTIN
IPC: A61K31/195
Filed: 1998-12-09
Abstract: The present invention relates to new uses of S-2(3-aminopropylamino)ethyl dihydrogen phosphorothioate (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, or radiation treatment. In particular, the invention provides a method for treating neurotoxicity and nephrotoxicity associated with the administration of chemotherapeutic agents.
Patent PT-1037607-E (PT)
Inventor: LINDER RUDOLF
IPC: A61K9/50
Filed: 1998-12-08
Abstract: Novel administration forms for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.
Patent PT-1079977-E (PT)
Inventor: LONDO MICHAEL G
IPC: D21H19/40
Filed: 1999-04-15
Abstract: A coating pigment composition comprising a hydrous clay, a caustic leached calcined clay, and a porous mineral provides a coating having excellent balance of color intensity and color definition characteristics when printed on by multicolored inks. The pigments of this invention offer a low cost alternative to conventional silica-based coatings in addition to affording other desirable benefits such as improved rheology, less required coat weights, and higher coating solids compared to conventional silica coatings.
Patent SG-37592-G (SG)
Title: Electric locking device for fittings like espagnolette bolts or bolt locks
IPC: E05C9/04
Filed: 1992-04-03
Abstract: A fitting for doors, windows or the like including an espagnolette or espagnolette lock fitted in a case in which is housed a control mechanism permitting the activation of at least one operating rod and an electrical blocking device. In order to avoid significant modifications to the standard espagnolette or espagnolette lock, the electrical blocking device is in the form of a separate assembly placed either at any place at the front edge of the leaf of the door or window, or aligned with the prolongation of and coupled with the case of the espagnolette or espagnolette lock.
Patent IE-34230-L (IE)
Title: Damp-course for cavity walls
IPC: E04B1/41
Filed: 1970-01-06
Abstract: An upstanding channel member, serving as a mounting for a door or window frame, has a rectangular or trapezoidal central portion received with all-around clearance in a space between two adjoining wall elements and bears with one or two transverse base flanges upon an end face of one or both wall elements. Two flat anchor members, secured to opposite sides of the central channel portion by a dovetail fit, are independently shiftable along these surfaces to fit between courses of building blocks or bricks constituting the wall elements. The mortar bonding these courses together flows into the clearance around the central channel portion and holds it, together with the anchor members, in position between the wall elements.
[US3707815A]
Patent IE-35096-L (IE)
Title: Storage of charge carriers
IPC: G11C19/28
Filed: 1971-01-19
Abstract: In monolithic semiconductor devices of the type wherein storage and manipulation of electronic signals representing information are accomplished by the storage and sequential transfer of packets of excess minority carriers localized in artificially induced potential wells, predictable directionality of charge-packet transfer requires that the potential well be asymmetrical, at least during the transfer operation. The instant invention includes the use of overlapping gate electrodes and/or nonuniform dielectric thicknesses under the gate electrodes of MIS structures so that an appropriately asymmetrical potential well always is formed whenever a voltage is applied to any gate electrode.
[US3651349A]
Patent IE-850085-L (IE)
Title: Whippable non-homogenized cream
IPC: A23L9/20
Filed: 1985-01-14
Abstract: PCT No. PCT/NL85/00003 Sec. 371 Date Sep. 9, 1985 Sec. 102(e) Date Sep. 9, 1985 PCT Filed Jan. 14, 1985 PCT Pub. No. WO85/02979 PCT Pub. Date Jul. 18, 1985.The invention relates to a whippable, non-homogenized cream having a fat content of 20 to 30% by weight and a pH of 6.2 to 6.5, which contains 0.2 to 0.4% by weight of at least one emulsifying agent consisting of a mixture of distilled monoglycerides in a carrier, wherein the weight ratio of saturated fatty acids to unsaturated fatty acids in the fatty acid ester is between 80:20 and 20:80, 0.2 to 0.4% by weight of at least one binder based on starch, as well as 0.03 to 0.06% by weight of carragheenate as a stabilizer, and to a method wherein at least one of said emulsifying agent, said binder, said carragheenate and at least one organic and physiologically acceptable acid are dispersed in milk and the amount of non-homogenized cream required to achieve the desired fat content in the final product.
[US4647465A]
Patent IE-37121-L (IE)
Title: Poultry feedstuff additive.
IPC: A23K1/165
Filed: 1973-01-22
Abstract: 1415093 Poultry feedstuff additives ROUSSEL-UCLAF 19 Jan 1973 [20 Jan 1972] 3022/73 Heading A5B Compositions for use as additives to poultry feedstuffs comprise, as the active ingredient for the production of larger eggs and the quantitative and qualitative increase of egg laying, one or more 13#-alkyl-17#-hydroxygona-4, 9, 11-trien-3-ones of the general formula: wherein R represents an alkyl radical; and either R' represents a C 2-4 unsaturated hydrocarbon radical, optionally halogen substituted or a C 3-5 cycloalkyl radical, in admixture with a vehicle which is non-toxic and metabolically acceptable to poultry, the composition containing from 1 to 1000 parts per million of the active ingredient. The active ingredient is preferably 17α-ethynyl-17#-hydroxy-estra-4, 9, 11-trien-3-one and/or 17α- methallyl-17#-hydroxy - estra-4, 9, 11-trien- 3-one. The poultry feedstuffs prepared from the additive compositions of the invention may also contain mineral salts, oligo elements, vitamins, antioxidants, protein extracts and/or coccidiostatics.
[GB1415093A]
Patent IE-820097-L (IE)
Title: Pressure cooker interlock
IPC: A47J27/08
Filed: 1982-01-19
Abstract: Pressure cooker (20) having a safety interlock including a resilient gasket (23) interposed between flat sealing surfaces (26, 34) of a receptacle (21) and a cover (22), and configured to form a seal against the surfaces when they are spaced by a first distance, and to prevent formation of the seal when the surfaces are spaced by a second, smaller distance. The receptacle and cover are provided with interlocking lugs (27) which are engageable in two different conditions to determine the first and second distances respectively. The gasket comprises an annular body (45) having inwardly directed, axially, diverging leg portions (46, 47) terminating in lip portions (50, 51) to seal against the sealing surfaces, and has faces with peripherally spaced bosses (54, 55) engageable by the sealing surfaces when at the second distance to decrease the divergence of the leg portions and so prevent seal formation. Y-shaped, V-shaped, and W- shaped cross sections for the gasket are shown. 
[WO8202699A1]
Patent IE-35012-L (IE)
Title: Binder for refractory material
IPC: C04B35/63
Filed: 1971-03-02
Abstract: 1357541 Producing refractory moulds IMPERIAL CHEMICAL INDUSTRIES Ltd 19 April 1971 [16 March 1970 11 Dec 1970 (2)] 12544/70 59032/70 and 59046/70 Heading B5A [Also in Divisions Cl and C3] Moulds are prepared by building up around an expendable pattern, e.g. of wood, a slurry containing a refractory material and a complex phosphate binding agent. The pattern is coated with wax or petroleum jelly, the slurry applied and if necessary other solid materials may be stuccoed on top. The process may be repeated until the required thickness is built up, the mould dried and fired.
[GB1357541A]
Patent IE-860329-L (IE)
Title: High frequency attenuation cable and harness
IPC: H01B7/00
Filed: 1986-02-05
Abstract: High frequency attenuation cable has a core surrounded by an EMI shielding layer. The core comprises at least one inner conductor, at least one high frequency absorption layer or non-amorphous magnetic metal tape surrounding, but not necessarily adjacent to, the inner conductor, and at least one dielectric layer surrounding, but not necessarily adjacent to, the inner conductor. The constructions according to the invention enable improved attenuation at frequencies in the range of 10-100 MHz.
[US4816614A]
Patent IE-900752-L (IE)
Title: Biocidal compositions and treatments
IPC: A01N57/02
Filed: 1990-03-02
Abstract: Phosphonium salts such as THP and aldehydes such as formaldehyde exhibit synergistic biocidal activity.
[EP0385801A1]
Patent IE-44100-L (IE)
Title: Phenylalkanols and their preparation
IPC: C07C255/37
Filed: 1976-04-30
Abstract: Phenylalkanols of the formula <IMAGE> wherein Ar is phenyl or phenyl monosubstituted or disubstituted by F, Cl, Br and/or CH3; X is F, Cl, Br or CN; m is 0 or 1; and n 2 or 3; possess antiinflammatory activity and can be produced by treating a compound of formula <IMAGE> wherein Q is a functionally modified hydroxy group and Ar, X, m and n have the values given above, with a solvolyzing agent.
[US4060633A]
Patent IE-790935-L (IE)
Title: Material for forming an adhesive film
IPC: C08L29/00
Filed: 1979-08-08
Abstract: A plasticizer-containing film of a partially acetalized polyvinyl alcohol resin contains as the plasticizer a mixture of an ester of an organic cyclic acid and/or a conventional acetal plasticizer for said resin, and an ester of an oxygen acid of phosphorus.
[US4361625A]
Patent IE-45144-L (IE)
Title: Isothioureas and heterocyclic compounds
IPC: A61K31/535
Filed: 1977-05-10
Abstract: S-(Aminoalkyl)isothioureas which have immunosuppressant activity. Two specific compounds are 2-(3-dimethylaminopropylthio)-2-imidazoline and N,N'-dimethyl-S-(3-dimethylaminopropyl)isothiourea.
[US4294854A]
Patent FI-803245-L (FI)
Inventor: DELFOSSE PIERRE
IPC: C09C3/00
Filed: 1980-10-14
Abstract: 1. Process for the manufacture of mineral fillers, especially natural calcium carbonates, by wet grinding, whereby 70-80% or more of the particles are < 1 mu m but a maximum of 15% of the particles are < 0.2 mu m, characterised in that the grinding is carried out without dispersant and at a solids concentration of less than 60% by weight, in that the ground suspension is filtered and the resulting filter cake which contains about 20% water is either dried or, by the addition of a dispersant, converted to a suspension of lower viscosity.
Patent FI-812001-L (FI)
Inventor: LORCH WERNER
IPC: F16K11/087
Filed: 1981-06-25
Abstract: A single mixing valve has a ball-like valve plug with hot and cold water inlet ports and outlet ports and a valve housing having a valve seat face of the same form as the plug. The housing has inlet ducts for the hot and cold water to be mixed and an outlet duct for the mixed water, the ducts porting into the face. A driving part is joined with the plug and is able to be rocked therewith for changing the rate of outlet of water from the valve and to be moved for changing the mixing ratio of the hot and cold water. The driving part is limited in its rocking motion to motion about a rocking axis running through a middle point of the plug and is limited to turning about an axis of turning running through the middle point. The valve has a guide plate, which may be turned in a plane parallel to the rocking axis of the driving part, with same in relation to the housing. The plate has a slot in which the driving part is keyed while being able to be moved along the slot. With this system it is not possible for the plug to be moved into skew positions.
Patent FI-830704-L (FI)
Inventor: LATTRELL RUDOLF
IPC: C07D501/36
Filed: 1983-03-02
Abstract: The invention relates to cephem derivatives of the general formula I <IMAGE>   and their physiologically acceptable acid addition salts, to pharmaceutical formulations active against bacterial infections, to processes for preparing the compounds and formulations, and to the use of the compounds for combating bacterial infections.
Patent FI-852837-L (FI)
Inventor: UMPLEBY JEFFREY DAVID
IPC: C08K5/57
Filed: 1985-07-19
Abstract: A crosslinkable composition comprising (A) a copolymer of ethylene and an unsaturated silane compound having hydrolysable group(s) optionally with other comonomers and (B) a defined dihydrocarbyl tin (IV) carboxylate compound as silanol condensation catalyst. The tin compound is preferably dibutyl tin maleate. The composition can be thermoformed to produce articles having improved surface finish.