baber/WOPTO huggingface dataset:
Patent NZ-502896-A (NZ)
Title: Tetrazole-containing rapamycin analogs with shortened half-lives
Inventor: MOLLISON KARL W
IPC: A61P9/00
Filed: 1998-09-24
Abstract: Rapamycin compounds of formula 1, 2 and 3 are disclosed. These compounds are useful in the preparation of medicaments for inhibiting restenosis, immune and autoimmune diseases, post-transplant-tissue transplant rejection, fungal growth, and cancer.
Patent NZ-503850-A (NZ)
Title: April - a novel protein with growth effects
Inventor: TSCHOPP JURG
IPC: A61K48/00
Filed: 1998-09-11
Abstract: A recombinant nucleic acid encoding an APRIL polypeptide comprising at least 102 amino acid residues.
Patent NZ-504595-A (NZ)
Title: Administration of CPAP treatment pressure in presence of apnea
Inventor: BERTHON-JONES MICHAEL
IPC: A61M16/00
Filed: 1998-11-06
Abstract: CPAP  treatment  apparatus  is  disclosed  having   a controllable  flow  generator  (34,  38,  40)  operable   to produce  breathable  gas  at a treatment  pressure  elevated above  atmosphere  to  a patient by  a  delivery  tube  (32) coupled  to  a mask (30) having connection with a  patient's airway.  A  sensor  (44,  50, 56,  58)  generates  a  signal representative  of  patient  respiratory   flow,   that   is provided  to a controller (54, 62, 64). The controller  (54, 62,  64) is operable to determine the occurrence of an apnea from  a  reduction in respiratory airflow below a threshold, and  if an apnea has occurred, to determine the duration  of the  apnea  and  to  cause the flow generator  (34,  38)  to increase  the treatment pressure by an amount  which  is  an increasing  function of the duration of  the  apnea,  and  a decreasing  function  of the treatment pressure  immediately before the apnea.
Patent NZ-506280-A (NZ)
Title: Medicinal compositions adhering to stomach/duodenum
Inventor: INAGI TOSHIO
IPC: A61K9/50
Filed: 1999-03-17
Abstract: A gastric and/or duodenal adhesive composition that adheres only to the mucosal of the stomach and/or duodenum and releases a medicament over time.  The composition is coated and comprises a medicament selected from water insoluble polymers, polyglycerin fatty acid esters, lipids and waxes.
Patent NZ-509808-A (NZ)
Title: Mammary-specific transcription factor BrEts
Inventor: L HUILLIER PHILLIP JOHN
IPC: C12Q1/68
Filed: 1999-08-30
Abstract: A isolated transcription factor BrEts polypeptide has the amino acid sequence as in Figure 2. Also described are nucleic acids encoding the polypeptide and cells comprising a vector with nucleic acid sequence. The polypeptide can be used to modulate the development of the mammary gland of a non-human animal and to manipulate milk protein synthesis to enhance the level of milk production, alter the composition of the milk and/or alter the timing of milk protein synthesis. Breast cancer can be diagnosed by monitoring the levels of expression or number of copies of the gene for the polypeptide.
Patent NZ-511564-A (NZ)
Title: Production of a zinc finger nucleic acid binding protein
Inventor: CHOO YEN
IPC: C07K14/47
Filed: 1999-11-09
Abstract: A method for producing a zinc finger nucleic acid binding protein is described.  The method comprises preparing a zinc finger protein according design rules, varying the protein at one or more positions, and selecting variants that bind to a target nucleic acid sequence by polysome display
Patent NZ-515535-A (NZ)
Title: Ultrasonic scanning apparatus
Inventor: KOBLANSKI JOHN
IPC: A61B8/08
Filed: 1999-04-16
Abstract: An apparatus for measuring physical characteristics comprises means to determine when an object (not shown) to be tested is correctly placed in the recess (12) of a main body (10). In a preferred embodiment the object is a foot and the device is useful in determining the presence of osteoporosis. An ultrasonic transmitter is resiliently mounted in a first container (30) slidably received in the main body (10). The transmitter is urged towards the object but its movement is restricted. A piezoelectric ultrasonic receiver (48) spaced from the transmitter also projects towards the body. The ultrasonic receiver is resiliently mounted in a second hollow container slidably received in the main body (10). The object is subjected to a first frequency obtained by resonating the transmitter in the thickness mode and a second lower frequency obtained by resonance in the radial mode.
Patent NZ-521882-A (NZ)
Title: Refiner measurement system and method
Inventor: JOHANSSON OLA M
IPC: D21D1/30
Filed: 2001-03-07
Abstract: A sensor (78), sensor refiner disk (58), correction system (162) and method used to measure a parameter in a refining zone of a refiner (30). Signals from one or more sensors of the sensor disk are processed by a processing device (164) and linked to a module (160) containing calibration data that is applied to help make sensor measurements more accurate. The module holds calibration data from sensors that are precalibrated before the sensor disk in which they are disposed is shipped, along with the module, to a fiber processing plant where the disk is installed in a refiner and the module connected to the processing device. In one preferred embodiment, the sensor or sensors are carried by a module comprising of a removable segment (32).
Patent NZ-522734-A (NZ)
Title: Compositions and methods for the diagnosis and treatment of herpes simplex virus infection using immunogneic portions of an HSV antigen
Inventor: HOSKEN NANCY A
IPC: G01N33/569
Filed: 2001-06-28
Abstract: An isolated peptide consists of an immunogenic portion of a HSV UL46 antigen wherein the antigen comprises an amino acid sequence set forth in SEQ ID NO:15 and the immunogenic portion is selected from the SEQ ID NO: 27-31 and 59-62. The polypeptide can be used in pharmaceutical composition useful for stimulating an immune response and antibodies that specifically bind the polypeptide can be used in methods for detecting HSV infection in samples from patients. Also described is incubating antigen presenting cells or peripheral blood cells, such as T cells, in the presence of the polypeptide and then incorporating the cells into a medicament for treating HSV.
Patent NZ-523060-A (NZ)
Title: Truck suspensions incorporating asymmetric leaf springs with full length and half length springs
Inventor: DUDDING ASHLEY T
IPC: B60G9/04
Filed: 2001-05-11
Abstract: A suspension system for supporting fore-and-aft extending frame members (6) of a vehicle chassis on a hollow axle (7) including a frame bracket (18) for pivotally supporting therefore or leading end of an asymmetric leaf spring (8), a spring end support (17) for supporting the aft or trailing end of the leaf spring, and an assembly for attaching the leaf spring at a location intermediate its opposite ends. The leaf spring is divided into two cantilever limbs (21, 22) extending in opposite directions from the centre line of the axle (7). One cantilever limb has a thickness substantially thicker than the other cantilever limb. At least one leaf of the asymmetric leaf spring extends the full length of the leaf spring. In a particular embodiment the shorter leaf has an end portion extending over the axle with an air spring (10) mounted either on the axle or on one side thereof.
Patent NZ-528191-A (NZ)
Title: Inflammation-inhibiting compounds derived from alpha-MSH and interleukin-1 beta and uses of alpha-MSH for confering tolerance to an antigen
Inventor: LUGER THOMAS
IPC: A23L33/18
Filed: 2002-02-08
Abstract: A compound selected from Lys-Pro or Lys-Pro-Thr can be used for the manufacture of a medicament for the treatment and/or prevention of an inflammatory skin disorder including allergic reaction, such as psoriasis, atopic dermatitis, contact allergies and food allergies.
Patent NZ-533154-A (NZ)
Title: Boats
Inventor: ROLFE DAVID WINDSOR
IPC: B63B7/04
Filed: 2000-10-09
Abstract: Bow and stern sections of a boat are hinged together to enable the bow section (1) to be folded over the stern section (2) which has wheels (6) deployed for towing and storage on land. The folded boat is towed by a towbar (10) bolted to a retracted spine (8) of a chassis (7) on which the stern section is mounted. The spine is extendable telescopically to support the unfolded bow section, and the wheels are pivotally-mounted on the chassis to be retracted by over-centre operation, into open-bottom compartments of the stern section. An interlock with the spine precludes wheel-retraction while the spine is retracted. Spring-biased doors are freed to close the open-bottoms of the compartment in response to retraction of the wheels. The hinging of the bow and stern sections is via a panel (5) which is pivoted to both sections and which closes a gap between bulkheads (3, 4) in the folded boat and provides a seat over them when the bow section is unfolded. (62) Divided out of 518769
Patent NZ-534130-A (NZ)
Title: Forfaiting transactions exchange system
Inventor: COLE TARA KIMBRELL
IPC: G06Q30/00
Filed: 2002-12-19
Abstract: A method of operating a computerised forfaiting exchange to develop forfaiting transactions for settlement comprises: - (a) Providing a website that is accessible via the internet to sellers and buyers using computers; (b) Providing a counter party selection document viewable on request, by the seller or buyer, at the website. Allowing the seller to identify classes of buyers who they will, or will not, develop a forfaiting transaction with; (c) Providing an offer document that is viewable at the website on request to a seller. The offer document contains the following:- a list of the classes of asset along with asset selection entry facilities; asset information entry facilities for entering the details of the asset; a list of terms for the offer along with offer selection and information entry facilities; a list of offer documents accompanying the offer together with offer selection entry facilities and offer document attachment facilities; a list of undertakings for the seller to make together with undertaking selection entry facilities and undertaking document attachment facilities; (d) Permitting the seller to create an instance of the offer document by: - identifying the asset, the terms, the offer documents and the undertakings to be made; (e) Permitting the seller to submit an instance of the offer document viewable to potential buyers from buyer classes identified by the seller; (f) Providing a counter offer document on request to the buyer after viewing an offer document. The counter offer document containing counter offer selection and counter offer information entry facilities for entering variations to an offer document instance; (g) Permitting the buyer to create and submit an instance of a counter offer document that becomes available to the seller; (h) Providing a counter offer document on request to any party, provided the party has viewed an instance of a counter offer document; and (i) Permitting the party to create an instance of a counter offer document so that it becomes available to the counter party.
Patent NZ-536966-A (NZ)
Title: Orally disintegrating tablets and process for obtaining them
Inventor: SEGADO FERRAN JAVIER
IPC: A61K9/20
Filed: 2003-06-04
Abstract: A tablet for oral administration that disintegrates in less than 30 seconds in the oral cavity and which can hardly be noticed on the tongue after disintegration.
Patent NZ-537029-A (NZ)
Title: Apparatus for moving objects, typically large panels and doors, with telescoping assemblies
Inventor: DROOMGOOL PATRICK CHARLES
Filed: 2003-05-13
Abstract: Disclosed is an apparatus (1) for lifting and moving objects (2), the apparatus including a mobile base means, a telescoping post means (6, 7), an object handling cradle and a cradle (50) adjusting means, wherein the telescoping post means is attached to the mobile base means and is substantially vertically disposed and being adapted with means to adjust the height of the post means between a retracted position and an extended position, the cradle adjusting means being adapted to be pivotably attached adjacent the top end of the post means in a horinzontal axis to enable the cradle to be adjustable in a vertical plane, the cradle having a substantially planar top surface and being adapted to be rotatably connected to the cradle adjusting means to enable the cradle to be rotatable in a horizontal plane and being adapted to support and transport an object to a desired position.
Patent NZ-537216-A (NZ)
Title: Process for the manufacture of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained
Inventor: ORESTE PASQUA ANNA
IPC: A61P17/06
Filed: 2003-06-17
Abstract: Describes a process for the preparation of N-acyl-(epi)K5-amine-O-oversulfate-derivatives and of its chemically or pharmaceutically acceptable salts, characterized in that: an (epi)K5-N-sulfate-derivative, in acidic form, is treated with a tertiary or quaternary organic base, letting the reaction mixture to stand for a time period of 30-60 minutes, maintaining the pH of the solution at a value of approximately 7 and its salt is isolated with said organic base; said salt of organic base of said (epi)K5-N-sulfate-derivative is treated with an O-sulfation reagent in the conditions of O-oversulfation; the (epi)K5-amine-O-oversulfate-derivative thus obtained is treated with a functional derivative of a carboxylic acid, the N-acyl-(epi)K5-amine-O-oversulfate-derivative is isolated. Further described are pharmaceutical compositions containing, as one of their active ingredients, and (epi)K5-N-amine-O-oversulfate.
Patent NZ-542682-A (NZ)
Title: Equine fitness monitoring
Inventor: EVANS DAVID
IPC: A61B5/00
Filed: 2004-03-26
Abstract: Apparatus for monitoring the status of a horse is disclosed. The apparatus includes: a blanket (1) which has a first sensor (5, 6) including a detector and a processing module (3), where the first sensor (5, 6) is adapted to generate indicating data indicative of at least one health status indicator, and a second sensor (11) for generating position data indicative of the position of the horse. In use, a processing system is adapted to determine, from the position data, movement data indicative of the rate of movement of the horse, and determine the health status of the horse using the indicating data and the movement data. At least one battery is connected to the first and second sensors and to a first part of an inductive coupling. The inductive coupling is provided in a recess in the processing module wherein in use, the battery is recharged by having the first part of the inductive coupling cooperate with a second part of the inductive coupling provided in a protrusion forming part of a hanging mechanism. The second part is coupled to an external power supply to thereby allow the battery to be charged when the blanket is hung on the hanging mechanism.
Patent NZ-548714-A (NZ)
Title: Highly soluble salt forms of imatinib for treating tumour diseases
Inventor: BURGER HANS MICHAEL
IPC: A61P35/02
Filed: 2005-02-03
Abstract: The disclosure relates to highly soluble acid addition salts of 4-[4-methyl-1-piperazinylmethyl]-N-[4-methyl-3-[[4-3-pyridinyl-2-pyrimidinyl]amino]phenyl]-benzamide (imatinib), which are selected from the group consisting of a (D)(-) tartrate salt or a (L)(+) tartrate salt, a succinate salt, and a malonate salt. Also described are other salts of imatinib such as a hydrochloride salt, a citrate sat, a malate salt, a fumarate salt, a benzoate salt, a benzenesulfonate salt, a pamoate salt, a formate salt, a 1,5-naphthalenedisulfonate salt, a salicylate salt, a cyclohexanesulfamate salt, a lactate salt, a mandelate salt, aq glutarate salt, an adipate salt, a squarate salt, a vanillate salt, an oxaloacetate salt, an ascorbate salt and a sulfate salt.
Patent NZ-552764-A (NZ)
Title: Composition comprising lactic acid and lactoferrin
Inventor: ANDERSCH BJOERN
IPC: A61K/
Filed: 2005-06-23
Abstract: Provided is a composition comprising lactic acid, and/or a salt thereof, and lactoferrin, and/or a peptide fragment thereof, which peptide fragment is based on the antimicrobial region of the lactoferrin molecule from the N-terminal end, for the treatment and/or prophylaxis of conditions in the urogenital tract, wherein the concentration of lactoferrin, and/or a peptide fragment thereof, is in the range of 0.0001 to 100 mg/ml, wherein said condition involves an elevated pH and/or a disturbed microbiota in the urogenital tract. Further provided is the use of the composition in the manufacture of medicaments to treat various urogenital tract medical conditions.
Patent NZ-562527-A (NZ)
Title: Cartridge connecting system with rotation locking means and angular indexing of the locked position
Inventor: HERLIER PATRICK
IPC: F17C13/04
Filed: 2006-04-25
Abstract: An assembly for connecting gas from a cartridge 20 into the combustion chamber of a gas powered hand operated tool includes an adapter 2 gas sealingly connecting the inlet 32 of a distribution member (solenoid valve 30) supplying gas into the combustion chamber to the outlet 23 of the gas cartridge 20. The adapter is mounted on either one of the distribution member or the gas cartridge and includes locking fins 15, 16, whilst a locking and indexing skirt 3 is mounted on the other of the distribution member and cartridge and includes locking notches 46 engageable with the locking fins for locking the cartridge against rotation relative to the tool, and at least one indexing ramp 45 cooperating with the locking fin in order to rotationally guide the cartridge toward a locked position in which the cartridge is locked against rotation relative to the tool.
Patent NZ-568304-A (NZ)
Title: One pot synthesis of tetrazole derivatives of sirolimus
Inventor: CHEN YONG
IPC: C07D498/18
Filed: 2006-12-12
Abstract: Disclosed is a method of preparing a rapamycin derivative zotarolimus molecule of formula I comprising: (a) reacting a molecule of formula II: with triflic anhydride to produce a molecule of the triflate and (b) reacting the molecule of the triflate with a molecule of formula IV: wherein R1 is selected from the group consisting of =O, and (H, OH); R2 and R5 are independently selected from the group consisting of H, -C(=O)R6, -C(=O)OR6, -C(=O) NHR6 and -C(=S)OR6; R3 is selected from the group consisting of =O and OR5; or R2 and R3 can be taken together to form moiety of formula A -C(R7)(R8) -O-B, where A is a bond to oxygen bonded to carbon 28 and B is a bond bonded to carbon 26 as defined above; R4 is selected from the group consisting of H and alkyl; R6 is selected from the group consisting of alkyl, cycloalkyl, aryl groups, and heterocyclic groups; R7 and R8 are independently selected from the group consisting of H, alkyl, or R7 and R8 taken together are =O R9 and R10 are independently selected from the group consisting of H, alkenyl, alkenylcycloalkenyl, alkenylcycloalkyl, alkyl, alkylcycloalkenyl, alkylcycloalkyl, alkynyl, aralkyl, aryl, cycloalkenyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, cycloalkenylalkyl, heterocyclyl, and combinations thereof, wherein the reactions are performed in a single pot.
Patent NZ-568818-A (NZ)
Title: Fishing de-hooking tool with self-adjusting pivoting guide at end to move sharp end of hook inwardly
Inventor: SHEPHERD GRAYDON AUBREY
IPC: A01K97/18
Filed: 2008-06-04
Abstract: A hook removal tool primarily for use in the removal of fish hooks. Hooks attached to a line and which are at least partially embedded in a fish or other substrate can be extracted using this tool. The tool includes a body with a handle at or adjacent a proximal end, and having a guide member pivotally connected at or adjacent a distal end. The guide member has at least one guide aperture or slot adapted to engage with the line or hook in such a manner that the line and at least the shank of the hook are able to slide through the aperture or slot. The tool can be slid down the line to the hook and used to dislodge the hook and then to remove the hook out of the fish's mouth. The guide member can self-adjust so that the sharp end of the hook is situated against a side of the body or positioned within a slot of cavity in the body.
Patent NZ-570180-A (NZ)
Title: Laminate/container formed from sheet wound on mandrel with selective application of pressure to form weakened areas for container corners
Inventor: LANCASTER BERTRAM ALAN
IPC: B65D3/00
Filed: 2008-07-29
Abstract: A method of forming a laminate material includes treating a sheet of planar material with adhesive, winding the material about a mandrel to form the laminate from plural layers of the material, applying pressure to a first portion of the material such that substantially stronger bonding occurs between layers in the first portion compared to a second portion which forms a controlled area of weakness Typically this allows for collapsible containers to be folded about the area of weakness.
Patent NZ-571900-A (NZ)
Title: Artificial fireplace
Inventor: O'NEILL NOEL
IPC: B05B17/06
Filed: 2007-03-13
Abstract: Disclosed is a simulated fire effect apparatus which includes an apertured bed, a container for a body of liquid and an ultrasonic transducer. The container provides a head space above the liquid and includes a vapour outlet port. The ultrasonic transducer device has a transducing surface operatively in liquid contacting relation with the body of liquid. The ultrasonic transducer is operable to produce a vapour in the head space. The apparatus further includes means for providing a flow of air along a path extending into the head space and out of the vapour outlet port. The outlet port is positioned so that the air flow path exits the container below the apertured bed and the means for providing a current of air is directed upwardly from the apertured bed.
Patent NZ-575202-A (NZ)
Title: A network based system for generating a test notification document
Inventor: KELLY ROBERT JOHN
IPC: H04L12/26
Filed: 2010-03-01
Abstract: A method and a network based system for generating a test notification document are disclosed. The system (1) includes (a) a server (3) capable of providing a register of unique identifiers; (b) at least one access device (2) capable of communicating with the server via the network and (c) a processing apparatus in communication with the server and access devices. . The access device is configured to facilitate input to the register of test criteria and the results of tests which are performed by a person. The processing apparatus is configured to generate a test notification document by comparing the test results to the test criteria.
Patent NZ-575673-A (NZ)
Title: Antibody specific for Angiopoietin-2
Inventor: OLINER JONATHAN DANIEL
IPC: A61P9/00
Filed: 2002-10-11
Abstract: An antibody specific for angiopoitin-2 (Ang-2), comprising the CDR1, CDR2 and CDR3 from SEQ ID NO: 11 and the CDR1, CDR2 and CDR3 from SEQ ID NO: 12. The antibody can be used for inhibiting undesired angiogenesis or treating one of cancer, ocular neovascular disease, obesity, hemangioblastoma, henarigioma, arteriosclerosis, inflammatory disease, inflammatory disorders, atherosclerosis, endometriosis, neoplastic disease, bone related disease or psoriasis. The antibody can also be used for modulating vascular permeability or plasma leakage. (62) Divided Out of 561548
Patent NZ-580429-A (NZ)
Title: Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
Inventor: SHAO LIMING
IPC: A01N43/00
Filed: 2008-06-02
Abstract: Disclosed are phenyl substituted cycloalkylamines represented by general formula (IV). The compounds are used for treating a neurological disorder, an eating disorder or for inhibiting reuptake of at least one monoamine from a cell in a mammalian subject.
Patent NZ-585262-A (NZ)
Title: Novel neurturin conjugates for pharmaceutical use
Inventor: AUSTEN MATTHIAS
IPC: A61K38/18
Filed: 2008-11-05
Abstract: Disclosed is a variant of human neurturin protein, or a biologically active fragment thereof, wherein said protein or fragment thereof has at least one amino acid change compared to human neurturin; wherein the amino acid change is in the region of amino acid positions 47-69 of mature human neurturin.