baber/WOPTO huggingface dataset:
Patent DE-60205872-T2 (DE)
Inventor: RIOU JEAN-FRANCOIS
IPC: C07D401/06
Filed: 2002-02-25
Granted: 2006-06-08
Abstract: The present invention relates to a compound of formula (I): wherein R5 is selected from the group consisting of 3-pyridyl, 5-pyrimidinyl, -CONH-(C1-C4 alkyl), -NHCO-(C1-C4 alkyl), halogen, -SO2NH2, -NO2, -CF3 or thien-2-ylcarbonyl and -CO2R where R can be hydrogen or C1-C4 alkyl; and Ar is selected from the group consisting of 5-imidazolyl, 2-pyrrolyl optionally substituted by a C1-C4 alkyl radical, 2-furyl or 2-thiazolyl, in the E or Z geometrical isomeric form or a mixture of the two geometrical isomeric forms. The invention is also directed to a method of treating primary and secondary tumours in a patient in need thereof comprising administering to the patient a therapeutically effective amount of a compound of formula I. The invention is also directed to a method of using a compound of formula I to treat cancer, inhibit the proliferation of a cell and induce cell apoptosis, comprising contacting a cell with an effective amount of the compound of formula I., The invention is also directed to a method of preparing the compound of formula I.
Patent DE-60217972-T2 (DE)
Inventor: SUDOR JAN
IPC: C12N9/16
Filed: 2002-10-14
Granted: 2007-11-15
Abstract: This invention relates to methods for enhancing the efficiency of biological processes that involve successive enzymatic reactions. More specifically, the invention relates to methods for enhancing the efficiency of an enzymatic purification process by increasing the temperature between successive enzymatic purification steps.
Patent DE-60218445-T2 (DE)
Inventor: DUMAS JACQUES
IPC: A61K31/444
Filed: 2002-04-18
Granted: 2007-11-29
Abstract: This invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy.
Patent DE-60219367-T2 (DE)
Inventor: KEOGH MARVIN
IPC: A61G3/00
Filed: 2002-09-26
Granted: 2007-12-13
Abstract: An aircraft medical unit comprises a front panel configured to fit in an aircraft cabin so as to form a divider inside the cabin and a spaced rear panel of substantially the same shape as that of the front panel. A side panel is constructed between the front and rear panels, and the front, rear and side panels defines a chamber. An access opening is formed in the front panel. A stretcher frame is provided and is movable between a folded and stowed position in the chamber and an unfolded and extended position to the outside of the chamber. The aircraft medical unit further includes at least one item of medical equipment used in the treatment of a patient.
Patent DE-60223488-T2 (DE)
Inventor: VALENTINI GUIDO
IPC: B23Q11/00
Filed: 2002-12-06
Granted: 2008-09-25
Abstract: A portable equipment for electric tool for the working of surfaces is described, that comprises a case-shaped container (1) including a plurality of compartments. A first compartment (40, 60) houses air suction means (16, 66), a second compartment (14, 70) is provided with an openable cover (26, 72) and houses filtering means (30, 81) and replaceable means (15, 71) for the collection of working dust contained in the sucked air and a third compartment (5, 90) is provided with an openable cover (6, 91) and is suitable for housing an electric tool and its accessories. The case-shaped container (1) is also provided with first connecting means (4, 3; 55, 56) for electrical and suction connection of the container (1) to the tool and with second connecting means (28, 12; 78, 62) for electrical connection of the container (1) to a power supply. The case-shaped container (1) can consist of a single body or can be made of distinct first and second case-shaped bodies (51, 99), said first body (51) being divided into said first and second compartments (60, 70) and being provided with said first (55, 56) and second (78, 62) connecting means, said second body (99) including said third compartment (90); there are provided means (93, 94) for coupling and uncoupling said bodies (51, 99). <IMAGE>
Patent DE-60226133-T2 (DE)
Inventor: MORAS DINO
IPC: C12P21/02
Filed: 2002-05-07
Granted: 2009-01-29
Abstract: The invention relates to polypeptides derived from the retinoic acid-related orphan receptor (ROR) in mammals, characterized in that they are delimited in their N-terminal extremity by an amino-acid located between positions 1 to 209, and in their C-terminal extremity by an amino-acid located between positions 450 to 452 of the rat RORbeta, alpha, or gamma, or by an amino-acid located at corresponding positions in nuclear receptor ROR of other subtypes than alpha, beta and gamma, and/or of the other mammals. The invention also relates to the use of these polypeptides, or of the molecular complexes or the crystals containing them, for carrying out:-a process for the screening of a ROR-LBD ligand which is an agonist, or an antagonist of said receptor,-or a process for the analysis of the tridimensional structure of the complexes formed with said polypeptides, molecular complexes or crystals and a particular compound.
Patent DE-60302244-T2 (DE)
Inventor: PRAT TERRADAS JAUME
IPC: G05G1/327
Filed: 2003-05-19
Granted: 2006-08-03
Abstract: A pedal security system for pedal mounting, particularly for motor vehicles, includes a pedal rotatably mounted on a pedal axis, an opening for receiving and retaining the pedal axis which is connected with an expandable slot wherein the expandable slot receives the pedal axis by exceeding a mechanical limit load of the pedal axis.
Patent DE-60308495-T2 (DE)
Inventor: POLAND D
IPC: G01H1/00
Filed: 2003-02-17
Granted: 2007-06-06
Abstract: A portable 3D ultrasound device having an ultrasound transducer. The ultrasound transducer includes a transducer array with a plurality of transducer elements arranged in a plurality of dimensions, the transducer array including an emitter to emit ultrasound energy, a receiver to receive responses generated in accordance with the ultrasound energy, a plurality of sub-array beamformers, a signal processor to convert the generated responses into a 3D ultrasound image and a display unit to display the 3D ultrasound image.
Patent DE-60310417-T2 (DE)
Inventor: SREEMANTHULA SRINIVAS
IPC: H04L29/06
Filed: 2003-08-28
Granted: 2007-09-27
Abstract: A method for reducing IP level signaling and radio resource load during the attachment or update L3 of a mobile unit to a cellular wireless communication network is disclosed wherein access network elements and routing network elements are provided, an identification element is transmitted from the mobile unit to one of the access network elements. The identification element indicates a current attachment of the mobile unit to one of the routing network elements. The transmitted identification element is checked so as to determine whether the access network element is provided with a connection to the one routing network element.
Patent DE-60310968-T2 (DE)
Inventor: NAESLUND MATS
IPC: H04L9/08
Filed: 2003-09-17
Granted: 2007-10-11
Abstract: A tamper-resistant security device, such as a subscriber identity module or equivalent, has an AKA (Authentication and Key Agreement) module for performing an AKA process with a security key stored in the device, as well as means for external communication. The tamper-resistant security device includes an application that cooperates with the AKA module and an internal interface for communications between the AKA module and the application. The application cooperating with the AKA module is preferably a security and/or privacy enhancing application. For increased security, the security device may also detect whether it is operated in its normal secure environment or a foreign less secure environment and set access rights to resident files or commands that could expose the AKA process or corresponding parameters accordingly.
Patent DE-60314495-T2 (DE)
Inventor: BEN-SASSON SHMUEL A
IPC: C07K14/21
Filed: 2003-02-07
Granted: 2008-03-13
Abstract: This invention relates to novel pharmaceutical penetration compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of treating or preventing diseases by administering penetration compositions to affected subjects.
Patent DE-60315778-T2 (DE)
Inventor: GARGANI ARMANDO
IPC: A62C99/00
Filed: 2003-06-09
Granted: 2008-06-05
Abstract: The sprinkling head (1) includes a nozzle holder cap (2) which is removably coupled to the body (3) of the sprinkling head and having multiple nozzles (4) designed for ejecting a fire fighting liquid in a nebulized form.
Patent DE-68902685-T2 (DE)
Inventor: SAMS BERNARD
IPC: B67D1/14
Filed: 1989-05-18
Granted: 1993-01-28
Abstract: A dispensing valve unit for a gasified beverage, which unit (1) is adapted to be operatively connected both to a container (2) of gasified beverage and to a container (3) of gas for topping up the said beverage container with gas, and is so arranged as, when operated, both to dispense the beverage by gravity flow and to cause topping up gas from the gas container, regulated to substantially the same pressure as exists in the beverage container, to be supplied to the beverage container to replace the beverage dispensed therefrom.
Patent DE-68912444-T2 (DE)
Inventor: LUCE DAVID A
IPC: A61B3/16
Filed: 1989-08-01
Granted: 1994-05-11
Abstract: An optical alignment system using at least one CCD array (28) for positioning an instrument in a chosen relationship to an object (20) is disclosed. Means for "electronically" aligning the optical components and providing a macro view of the object on a CRT (66) without additional illumination are also disclosed. Alignment may be achieved manually, if the operator observes the position of symbols on the CRT that move in response to movement of the instrument by the operator using a joystick (6), or automatically using information provided by the array.
Patent DE-68918391-T2 (DE)
Inventor: UENO RYUZO
IPC: A61K31/557
Filed: 1989-09-29
Granted: 1995-01-19
Abstract: The present invention relates to an ocular hypotensive composition and a composition for treatment of glaucoma which comprises an amount of 20-substituted 15-keto-PGs effective as an ocular hypotensive agent; these compounds exhibit no or little side effect such as transient ocular hypertensive response, hyperemia of conjunctiva or of iris, dacryops, lema, closed eye and the like.
Patent DE-68925386-T2 (DE)
Inventor: RUOZI GIUSEPPE
IPC: A23L3/04
Filed: 1989-05-31
Granted: 1996-06-27
Abstract: Foodstuff packaged in a material transparent to microwaves is conveyed continuously through an environment pressurized to 2.5 bar max so as to prevent the containers or wrappers bursting or being forced out of shape; in four steps, the temperature is raised quickly to a prescribed treatment value with high frequency microwave radiation, stabilized by applying a combination of lower power microwaves and hot air, held steady with hot air only, and then lowered by cooling. In a split-level cylindrical oven, the upper level consists in a pressure-and-temperature compensating chamber (4), a high speed heat chamber (5) with closely spaced microwave generators (24) ordered in longitudinal rows along its top and sides, the waveguides (24 min , 25) of which are directed at the containers or wrappers (C) of of foodstuff from above and beneath as they are indexed through on special pallets (S), and a stabilization chamber (5 min ) in which lower power microwaves combine with air drawn through heaters (20) and circulated by a fan (21) located at the closed end of the oven; the same air is used to heat a vertical chamber (6), through which the pallets descend on an elevator (D) before passing into a cooling chamber (7) on the lower level and proceeding toward the final outgoing compensating chamber (8). Once out of the oven, the pallets (S) are raised by a further elevator (A) to the upper level for emptying and reloading.
Patent DE-69003312-T2 (DE)
Inventor: BASIN GERARD
IPC: A01G27/00
Filed: 1990-06-11
Granted: 1994-04-28
Abstract: The invention relates to novel sheets of fibrous material used for irrigation in horticulture. The irrigation sheet according to the invention is constituted by a non-woven veil of discontinuous glass fibres linked together by means of a non-toxic and non-water-repellent binder or one rendered such, by means of non-toxic surfactants, the veil exhibiting a mass per square metre of surface, or weight, lying between 50 and 300 g/m<2>.
Patent DE-69004587-T2 (DE)
Inventor: GEORGEVICH GRADIMIR G
IPC: G01N33/558
Filed: 1990-01-31
Granted: 1994-05-11
Abstract: An improved chromatographic device and method for quantitating the activity of an enzyme utilizes a bibulous test strip as the stationary phase, an aqueous solution as the mobile phase, and a chromophore as the indicator. The enzyme activity is quantitated by transforming a substantially depletable amount of a chromogenic substrate from soluble chromogen to insoluble chromophore as the mobile phase advances, whereupon the insoluble chromophore becomes immobilized on the test strip to produce a column of color. The length and/or the intensity of the column of color are related to the activity of the enzyme. The present invention is useful for the direct determination of enzyme-analytes and for the indirect determination of analytes which can be coupled to an enzyme.
Patent DE-69011149-T2 (DE)
Inventor: FUCHIKAMI TAKAMASA
IPC: C07C247/22
Filed: 1990-02-05
Granted: 1995-04-06
Abstract: A fluorine-containing  alpha , omega -bifunctional compound having the formula:  R<1> @HCH2(CF2)nCH2 @HR<2>      (I)   wherein each of R<1> and R<2> independently is a hydrogen atom, an alkyl group or an aralkyl group; X is -COOH, -COOR<3>, -COY or -NCO, wherein R<3> is an alkyl group or an aralkyl group and Y is a halogen atom or N3; and n is an integer of at least 1 provided that when X is -COOH, n is an integer of at least 4.
Patent DE-69015485-T2 (DE)
Inventor: ABONDANCE ROGER
IPC: A63C5/075
Filed: 1990-07-16
Granted: 1995-05-11
Abstract: Device comprising a plate (5) which, receiving the pair of bindings, is positioned at a distance from the upper face of the ski without possibility of movement in the direction lateral to the ski. 
<??>According to the invention, the plate (5) is associated with means (9, 10) permitting its displacement longitudinally to the ski, against the action of at least one elastic support (13) on each of its ends. 
<??>Application to the fitting-out of alpine skis. 
<IMAGE>
Patent DE-69020007-T2 (DE)
Inventor: RHIND STEPHEN KEITH
IPC: A61K47/48
Filed: 1990-02-12
Granted: 1995-11-23
Abstract: Cross-linked labelled antibody conjugates are described which have at least one non-disulphide interchain bridge. The bridge may be the residue of a homo- or hereofunctional cross-linking reagent, and is located away from the antigen binding domains of the antibody. The antibody conjugates have an enhanced binding capacity and in vivo have good blood clearance and, in the presence of a tumour high tumour: blood and tumour: bone ratios. The conjugates are of use in the diagnosis and therapy of e.g. tumours and may be prepared by reaction of a cross-linking reagent with an antibody.
Patent DE-69020588-T2 (DE)
Inventor: GOODWIN GEORGE
IPC: B60K17/26
Filed: 1990-01-10
Granted: 1996-04-04
Abstract: A power transmission unit for coupling a prime mover to a vehicle, in particular a bicycle has a clutch means (40), a gear train (10), and a freewheel means (17). The output shaft of the prime mover is connected to the input side (40a) of the clutch means (40). The output of the clutch means (40b) is connected to the input side (21) of the gear train (10). The output side (24) of the gear train is connected to the freewheel means (17). The freewheel means (17) is connected to a sprocket wheel. The sprocket wheel together with another sprocket wheel is mounted on a common freewheel which in turn is mounted on the crankshaft of the bicycle. The other sprocket wheel is connected to the rear wheel of the bicycle. In the absence of power from the prime mover, the bicycle may be used in a conventional manner. When in use, the prime mover drives the rear wheel of the bicycle via the clutch (40), gear train (10), freewheel means (17), sprocket wheels and the rear wheel.
Patent DE-69030483-T2 (DE)
Inventor: ETTINGER KAMIL
IPC: G01N23/221
Filed: 1990-05-08
Granted: 1997-11-27
Abstract: The invention relates to an apparatus and method for detecting the presence of an element of interest within an object. The object is positioned where a beam of gamma rays of the required energy are directed to be scattered by the element of interest. The gamma rays are provided by excited atoms of the element of interest. The excited atoms result from the reaction of hydrogen or heavier ions and a suitable target. The excited atoms deexcite, releasing gamma rays which are scattered by the element of interest within the object. The scattered gamma rays are detected, output signals are produced, processed and analyzed to determine the amount of the element of interest within the object. A preferred embodiment relates to the detection of nitrogen-based explosives in luggage.
Patent DE-69033262-T2 (DE)
Inventor: HARARI ELIYAHOU
IPC: H01L21/8247
Filed: 1990-03-30
Granted: 2000-02-24
Abstract: A system of Flash EEPROM memory chips with controlling circuits serves as non-volatile memory such as that provided by magnetic disk drives. The memory cells of the Flash EEPROM are partitioned into a plurality of sectors that individually are erasable together as a unit. The individual sectors are provided with a user data portion and an overhead portion which allow for operations similar to that of a magnetic disk drive. In one embodiment, information about defect mapping of cells for a sector is maintained in the overhead portion and used to map defective cells or the whole sector to spare ones. In another embodiment, an error correction code of the data in the user data portion is maintained in the overhead portion.
Patent DE-69101466-T2 (DE)
Inventor: NICOLL GREGG ALAN
IPC: A61K8/58
Filed: 1991-05-07
Granted: 1994-07-14
Abstract: A water-in-silicone oil emulsion, suitable for topical application to mammalian skin or hair, comprises, in addition to water, a volatile polydimethylsiloxane, a silicone surfactant ingredient comprising a polymer of dimethylpolysiloxane with polyoxyethylene and/or polyoxypropylene side chains having a molecular weight of from 10,000 to 50,000, a 2-hydroxyalkanoic acid or derivative thereof, ultrafine titanium dioxide, and an inorganic electrolyte.
Patent DE-69108830-T2 (DE)
Inventor: MATSUO HISAYUKI
IPC: A61K38/00
Filed: 1991-04-20
Granted: 1995-09-14
Abstract: A novel physiologically active peptide originating in hog, represented by structural formula (I), and an acid addition salt thereof wherein terminals (1) and (2) are directly bonded to each other and so are terminals (3) and (4), and cystein residues (Cys) in the 6- and 22- positions form an intramolecular S - S bond with each other. Since it has both natriuretic and hypotensive activities, it is useful for treating cardiac edema, renal edema, hepatic edema, hypertension, congestive failure, and acute and chronic renal insufficiency. Since it has also activities of inhibiting the growth of vascular smooth muscle cells and producing cGMP, it is expected to be efficaceous against atherosclerosis.
Patent DE-69115135-T2 (DE)
Inventor: GIANNESSI FABIO
IPC: C07D401/12
Filed: 1991-06-20
Granted: 1996-05-09
Abstract: 1-alkyl-3-(acylamino)- epsilon -caprolactames of formula (1) <CHEM>  wherein R is selected from the group consisting of:     pyrrolidin-2-one-1-acetyl,     p-methoxybenzoyl,     N-benzyloxycarbonyl-(S)-prolyl,     phenylbutanoyl,     3-trifluoromethylbenzoyl,     3,4,5-trimethoxybenzoyl,     nicotinoyl, and     acyl having from 1 to 5 carbon atoms, and R1 is selected from the group consisting of:     hydrogen,     methoxycarbonylmethyl,     aminocarbonylmethyl,     2-hydroxyethyl, and     formylmethyl, (provided that, if R1 is hydrogen, R is not formyl or acetyl) are potent enhancers of learning and memory. Orally or parenterally administrable pharmaceutical compositions in unit dosage form comprise from about 100 to 500 mg of one of the compound of formula (1).
Patent DE-69127429-T2 (DE)
Inventor: LOVELL JAMES BYRON
IPC: A01N43/36
Filed: 1991-11-18
Granted: 1998-01-02
Abstract: This invention relates to new insecticidal and synergistic miticidal compositions containing as essential active ingredients an arylpyrrolecarbonitrile or arylnitropyrrole and an arylpyrazolecarboxamide. The invention also relates to a method for protecting growing plants from infestation and attack by insects and plant mites comprising applying to the foliage and stems of said plants an insecticidally and miticidally effective amount of a composition containing a synergistic mixture of an arylpyrrolecarbonitrile or arylnitropyrrole and an arylpyrazolecarboxamide dispersed in an inert diluent, or sequentially applying to the foliage and stems of plants which are to be protected from attack by insects and plant mites, an arylpyrazolecarboxamide and a synergistically effective amount of an arylnitropyrrole or arylpyrrolecarbonitrile.
Patent DE-69219511-T2 (DE)
Inventor: DE NORA ORONZIO
IPC: C25C1/18
Filed: 1992-02-25
Granted: 1998-01-02
Abstract: The anode of the invention is particularly suitable for oxygen evolution from acid solutions containing fluorides or fluorocomplex anions, used for deposition of metals. The anode is of the ceramic type, consisting of tin dioxide comprising additives to promote sinterization and increase the electrical conductivity. In a preferred embodiment of the invention the ceramic anode comprises an electrocatalytic layer for oxygen evolution comprising oxides of manganese, cerium and praseodymium, suitably doped. In a particularly preferred embodiment of the present invention said anode comprises a further external layer of zirconyl phosphate.
Patent DE-69221725-T2 (DE)
Inventor: RINK TIMOTHY
IPC: A61K38/22
Filed: 1992-05-23
Granted: 1997-12-18
Abstract: PCT No. PCT/US92/04357 Sec. 371 Date Nov. 24, 1993 Sec. 102(e) Date Nov. 24, 1993 PCT Filed May 23, 1992 PCT Pub. No. WO92/20367 PCT Pub. Date Nov. 26, 1992Method for treatment of a patient suffering from anorexia or a related condition by administering amylin or an analogue thereof and/or to the patient in an amount sufficient to increase amylin and/or insulin levels in the plasma of the patient.
Patent DE-69232751-T2 (DE)
Inventor: ASBURY R
IPC: G01S13/931
Filed: 1992-05-04
Granted: 2003-05-28
Abstract: A Doppler control circuit for a CW or pulse Doppler radar system for monitoring not only the phase shift between echo signals from several targets but also the amplitude difference between the several targets and to further tune the radar to a particular target among one or more targets from which echo signals return. The control circuit can be used in state of the art CW or pulse Doppler type radar systems. In a further system, a continuously generated radar signal is repeatedly transmitted at different frequencies in time division fashion to define a succession of transmit and receive frames. The receive frames are divided into a plurality of time interval windows with selected windows being used to detect received signals at the different frequencies. The remaining windows can be used for subsystems of the radar system. The rate of phase shift of received signals at a reference frequency is used to determine closing rate (positive or negative) while the phase shift difference between received signals at two frequencies is used to determine range and target direction. In yet a further system, a special circuit is provided for conditioning selected portions of the Doppler frequency spectrum to attenuate or de-emphasize portions of the echo signal corresponding to selected targets in the radar system environment, such as rain or stationary wayside objects, in order to give such echo signals less weight in determining roadway hazards.