baber/WOPTO huggingface dataset:
Patent AU-2018234644-A1 (AU)
Title: Use of designer receptors exclusively activated by designer drugs in the treatment of seizure disorders
Inventor: DURING MATTHEW
IPC: A61P3/04
Filed: 2018-03-15
Abstract: Methods and compositions for treating a seizure disorder are provided which include administering to the patient a vector encoding a modified receptor for delivery of the modified receptor to the target location, the modified receptor being modified to be activated by a synthetic ligand, wherein the modified receptor inhibits neuronal firing when activated; and administering to the patient the synthetic ligand. Also provided are methods and compositions for treating a seizure disorder in a patient in need thereof by administering to the patient a vector encoding a modified receptor for delivery of the modified receptor to the target location, the modified receptor being modified to be activated by a synthetic ligand, wherein the modified receptor increases neuronal firing when activated; and administering to the patient the synthetic ligand. The methods are used to improve or alleviate one or more symptoms of a seizure disorder.
Patent AU-2018263156-A1 (AU)
Title: Strap-based exercise system
Inventor: SIU ANDREW S P
IPC: A63B21/055
Filed: 2018-05-04
Abstract: A strap-based suspension exercise system (100), includes a main strap (102) that is attached to a fixed or stationary object to anchor the exercise system (100) and exercise straps (104) that are used to perform a variety of exercises. Different main straps (102) are provided that enable anchoring the exercise system (100) virtually anywhere. The exercise straps (104), which may be inelastic or elastic are attached to the main strap (102) using a uniquely designed buckle (106) and include a safety strap (1910). The exercise system (100) can be used virtually anywhere for perform a wide variety of exercises.
Patent AU-2018263420-A1 (AU)
Title: Converter control device, converter provided with same, air conditioner, and converter control method and converter control program
Inventor: SATO TAKESHI
IPC: H02M7/06
Filed: 2018-04-13
Abstract: Provided is a converter device that is inexpensive and that reduces noise occurring from an inductive element while using a carrier frequency in an audible range. A converter control device (15) for a converter is provided with: a reference waveform generation unit (30) that generates a reference waveform of a predetermined carrier frequency in an audible range; a first waveform generation unit (31) that generates a first waveform changing, in a predetermined frequency range, the shape of the reference waveform generated by the reference waveform generation unit (30); a voltage command generation unit (32) that generates a voltage command; a switching signal generation unit (34) that compares the first waveform with the voltage command and outputs a switching signal Sg for determining an on/off duty ratio of a switching element; and a drive unit (35) that turns on and off the switching element on the basis of the switching signal Sg.
Patent AU-2018273206-A1 (AU)
Title: Polyolefin silicon coating composition
Inventor: MCVAY ROBERT
IPC: C09D183/04
Filed: 2018-05-22
Abstract: A coating composition comprising a polyolefin component and a silicon component, wherein the composition comprises 5.0 wt% or greater silicon-containing material, based on total solid weight of the composition, is disclosed. Substrates coated at least in part with such a coating composition, including packages such as metal cans, are also disclosed.
Patent AU-2018278882-A1 (AU)
Title: A gaming machine and method for providing a feature game
Inventor: OLIVE SCOTT CHRISTOPHER
IPC: A63F13/45
Filed: 2018-12-11
Abstract: A gaming machine comprising a symbol selector for selecting a plurality of symbols from a set of symbols for display during play of a game, the set of symbols including a plurality of non 5 configurable symbols, a plurality of configurable symbols, and a plurality of reveal symbols, the symbol selector configured to respond to one or more reveal symbols being selected by selecting a replacement symbol, from a set of replacement symbols that includes a configurable symbol, to replace each reveal symbol; a value assigner for randomly assigning a prize value to at least each selected 10 configurable symbol, including any configurable symbols that replace reveal symbols; and an outcome evaluator for monitoring play of the game, wherein a feature game is triggered in response to a trigger event, the trigger event comprising a defined number of configurable symbols being selected by the symbol selector for display; wherein, until an end condition is met in the feature game, the symbol selector is 15 further configured to: 1) hold any selected configurable symbols; 2) remove any selected non-configurable symbols from the display; and 3) replace any removed non-configurable symbol with another symbol selected from a feature game set of symbols that includes non-configurable symbols 20 and configurable symbols. 10922899_1 (GHMatters) P98189.AU.12
Patent AU-2018285677-A1 (AU)
Title: Tetrahydropyridopyrazine modulators of GPR6
Inventor: BROWN JASON W
IPC: A61K31/445
Filed: 2018-06-15
Abstract: Disclosed is a compound of Formula 1 as described in the specification and a pharmaceutically acceptable salt thereof. This disclosure also relates to materials and methods for preparing the compound of Formula 1, to pharmaceutical compositions which contain it, and to its use for treating diseases, disorders, and conditions associated with GPR6.
Patent AU-2018293922-A1 (AU)
Title: Improvements to fitting orthokeratology lenses
Inventor: GIFFORD PAUL
IPC: G06T7/00
Filed: 2018-06-28
Abstract: A method for fitting OK lenses to a patient comprising the steps of: applying a corneal topography apparatus to a patient to capture baseline and post wear maps of a cornea of the patient in a computer to thereby derive a difference map; processing the difference map to fit Zernike polynomials thereto wherein weights of said fitted polynomials comprise features of a test feature vector for the difference map; applying the test feature vector to a classification machine trained to classify the difference map as one of a number of predetermined classes; and subsequently treating the patient taking into account the classification machine's classification.
Patent AU-2018313839-A1 (AU)
Title: Rack level power control
Inventor: HALL DAVID JAMES ASHER
IPC: G06F1/32
Filed: 2018-08-08
Abstract: In some examples, a method includes acquiring status information of at least one resource of a data center, estimating, based on the status information, whether load on a power supply will exceed a threshold value at a time subsequent a time of the estimating, and in response to estimating that load on the power supply will exceed the threshold value at the time subsequent the time of the estimating, transmitting a command signal to a server rack that is coupled to the power supply to configure equipment of the server rack to operate at a reduced power supply level that is reduced from a power supply level at the time of the estimating and that is based on a service level agreement associated with the server rack.
Patent AU-2018322393-A1 (AU)
Title: Dental matrix devices
Inventor: SMITH WADE ROBERT MICHAEL
IPC: A61C5/00
Filed: 2018-08-24
Abstract: A dental matrix device may include a body and a clamp retainer. The body may include a clamp cavity, an aperture, and a ramp immediately adjacent to the aperture. The clamp retainer may be at least partially positioned in the clamp cavity. The clamp retainer may be at least partially positioned in the clamp cavity and may include a clamp portion at a first end that may include a levered portion that is rotatably connected to a base. Translation of the clamp retainer in a first direction may draw the clamp retainer into the clamp cavity such that a lower surface of the levered portion rotates towards an upper surface of the base. Translation of the clamp retainer in a second direction may push the levered portion up the ramp to separate the lower surface of the levered portion from the upper surface of the base.
Patent AU-2018322769-A1 (AU)
Title: Daptomycin formulations
Inventor: BEVETEK MOCNIK ANITA
IPC: A61K47/18
Filed: 2018-08-28
Abstract: The present invention relates to compositions comprising daptomycin and at least one amino acid, methods of providing such compositions and the uses thereof.
Patent AU-2018335798-A1 (AU)
Title: Developer Supply System, Developer Supply Container Mounting Method and Developer Supply Unit
Inventor: MAKINO YUSAKU
IPC: G03G15/08
Filed: 2018-09-21
Abstract: This developer replenishment container is attachable to and detachable from a developer receiving device that comprises a developer receiving section wherein a receiving port for receiving developer is formed, and comprises an engaged section 11b integrally displaceable with the developer receiving section. The developer replenishment container comprises a discharge section wherein a shutter opening for discharging developer accommodated in a developer accommodation section is formed. After the developer replenishment container is mounted to a prescribed position on the developer receiving device, an operation part 21 performs a prescribed operation to engage an engaging section 21d with the engaged section 11b, thereby causing the developer receiving section to be displaced such that the receiving port is in communication with the shutter opening.
Patent AU-2018386215-A1 (AU)
Title: Methods and compositions for treating cancer using exosomes-associated gene editing
Inventor: KALLURI RAGHU
IPC: C12N15/113
Filed: 2018-12-14
Abstract: Provided herein are compositions comprising exosomes comprising CD47 on their surface, and further comprising a CRISPR system. Further provided are methods of using the exosomes for gene editing and the treatment of cancer by gene editing.
Patent AU-2018440086-A1 (AU)
Title: Antenna and mobile terminal
Inventor: CHEN FENGWEN
IPC: H01Q1/36
Filed: 2018-09-07
Abstract: The present application relates to an antenna and a mobile terminal, wherein the antenna comprises a conductive support and a feed portion; the conductive support comprises a first segment, a second segment, a third segment, and a fourth segment that are all made of a conductive material and that jointly enclose to form a cavity; the first segment and the third segment are arranged opposite each other and respectively connect to head and tail ends of the second segment, while the fourth segment and the second segment are arranged opposite each other; the second segment is disposed at an inner side of a display screen of a mobile terminal, the third segment is a part of a side framework of the mobile terminal, and the fourth segment is located at an outer side or inner side of a rear cover of the mobile terminal or is a part of the rear cover; the conductive support is provided with a gap, and the gap is provided between the fourth segment and the first segment or at the fourth segment. The feed portion is used for feeding in an electromagnetic signal and exciting the conductive support to generate a current, and by means of providing the cavity and the gap, the antenna is able to irradiate an electromagnetic signal. The antenna provided by the present application has low clearance environment requirements and may also meet antenna radiation capabilities.
Patent AU-2019200592-A1 (AU)
Title: BPI and its congeners as radiation mitigators and radiation protectors
Inventor: GUINAN EVA
IPC: A61K38/08
Filed: 2019-01-30
Abstract: Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or intentional, such as therapeutic), chemoradiotherapy, disease, toxin, or drug or biologic mediated therapy.
Patent AU-2019200623-A1 (AU)
Title: Compositions and methods for the treatment of presbyopia
Inventor: HORN GERALD
IPC: A61K31/00
Filed: 2019-01-31
Abstract: Abstract The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably use aceclidine separate or together with a cycloplegic agent and/or with a nonionic surfactant and viscosity enhancer, and or with low concentrations of a selective a-2 adrenergic receptor agonist.
Patent AU-2019201424-A1 (AU)
Title: Vaccines having an antigen and interleukin-21 as an adjuvant
Inventor: WEINER DAVID B
IPC: A61K48/00
Filed: 2019-02-28
Abstract: Disclosed herein is a vaccine comprising an antigen and IL-21. Also disclosed herein are methods for increasing an immune response in a subject. The methods may comprise administering the vaccine to the subject in need thereof.
Patent AU-2019203695-A1 (AU)
Title: Mobile computer workstation
Inventor: ABU-AKEL FOUAD GERIES
IPC: A47B21/013
Filed: 2019-05-27
Abstract: A mobile computer workstation is disclosed and generally includes a base assembly, a power supply, a column assembly, a tray assembly, a monitor support assembly and a tray controller. The workstation can be configured with a variety of storage solutions for any number of work environment and tasks. The tray assembly can house a computer that is integrated into the workstation. The tray controller provides a measure of security for the workstation by allowing access to the workstation and control over its features by only authorized users.
Patent AU-2019203887-A1 (AU)
Title: Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types
Inventor: MONTEFELTRO ANDRÉS PABLO
IPC: A61K47/55
Filed: 2019-06-04
Abstract: The invention provides a conjugate comprising (i) a nucleic acid which is complementary to a target nucleic acid sequence and which expression prevents or 5 reduces expression of the target nucleic acid and (ii) a selectivity agent which is capable of binding with high affinity to a neurotransmitter transporter. The conjugates of the present invention are useful for the delivery of the nucleic acid to a cell of interests and thus, for the treatment of diseases which require a down-regulation of the protein encoded by the target nucleic acid as well as for the delivery of imaging agents to the 10 cells for diagnostic purposes.
Patent AU-2019205780-A1 (AU)
Title: Process for aligning targeted nucleic acid sequencing data
Inventor: BEAN GORDON JEFF
IPC: G16B25/20
Filed: 2019-01-07
Abstract: Provided is a computer-implemented method of aligning RNA including receiving onto a data storage unit primer sequences and transcript sequences transcribable from a reference genome based on a gene model, generating target sequences to be amplified from a combination of the primer sequences and the transcript sequences, generating a modified reference genome based on the plurality of target sequences, aligning sequence reads generated from a test sample comprising RNA amplicon molecules to the of target sequences, and generating an alignment profile for the test sample based on the aligning. Also provided is a computer system for performing the foregoing method.
Patent AU-2019241321-A1 (AU)
Title: N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof
Inventor: ZHANG YINSHENG
IPC: C07D207/34
Filed: 2019-03-29
Abstract: A N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, and a pharmaceutical composition and use thereof, specifically relating to a compound as represented by formula I, a stereoisomer, a tautomer, a geometrical isomer, a solvate, an active metabolite, a hydrate, a prodrug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and a medical use thereof. The medical use comprises the use in treating diseases benefiting from the capsid protein assembly inhibitor, and in particular, diseases caused by hepatitis B virus infection.
Patent AU-2019270163-A1 (AU)
Title: Synthesis of tipifarnib
Inventor: REN PINGDA
IPC: C07B55/00
Filed: 2019-05-17
Abstract: Provided herein are methods of preparing a desired enantiomer 6-[amino(4- chlorophenyl) (1 -methyl- 1H-imidazol-5-yl) methy1]-4-(3-chlorophenyl)-1 -methyl-2(1H)- quinolinone, otherwise known as tipifarnib.
Patent AU-2019273689-A1 (AU)
Title: Aerosol generation
Inventor: REES KELLY
IPC: A24F40/46
Filed: 2019-05-24
Abstract: The invention provides an aerosolisable material for use in an aerosol generating assembly, the aerosolisable material comprising a tobacco material, an un-encapsulated flavourant and an encapsulated flavourant.
Patent AU-2019277353-A1 (AU)
Title: Electronic content based on neural networks
Inventor: HADDADNIA JUSTIN
IPC: H04N5/262
Filed: 2019-05-29
Abstract: Systems and methods for modifying a property of a post are provided. A post that includes image content, textual content, and amount content is posted to a platform. Engagement activity data for the post is collected. A matrix that includes scores for properties of the image content, the textual content, audio content, and the amount content is generated. The matrix, the engagement activity data, and engagement information associated with multiple previously posted posts are used to generate an estimated success level of the post. Depending on the estimated success level for the post, a post property may be modified and the post with the modified property replaces the post on the platform.
Patent AU-2019283923-A1 (AU)
Title: Intelligent automated assistant
Inventor: GRUBER THOMAS R
IPC: G10L15/00
Filed: 2019-12-19
Abstract: The intelligent automated assistant system engages with the user in an integrated, conversational manner using natural language dialog, and invokes external services when appropriate to obtain information or perform various actions. The system can be implemented using any of a number of different platforms, such as the web, email, smartphone, and the like, or any combination thereof. In one embodiment, the system is based on sets of interrelated domains and tasks, and employs additional functionally powered by external services with which the system can interact.
Patent AU-2019340675-A1 (AU)
Title: Dopamine D3 receptor selective antagonists/partial agonists and uses thereof
Inventor: NEWMAN AMY HAUCK
IPC: C07D405/12
Filed: 2019-09-09
Abstract: Disclosed herein are novel methods of treating pain in a patient in need thereof by providing to the patient a selective dopamine D3 receptor antagonist/partial agonist which when used with an opioid analgesic, can mitigate the development of opioid dependence, by preventing the need for dose escalation while either maintaining the opioid analgesic effect or providing analgesia with a lower dose of the opioid. In addition, the D3 antagonists/partial agonists described herein may be used to augment the effectiveness of current Medication Assisted Treatment regimens (e.g. methadone or buprenorphine) for the treatment of opioid use disorders.
Patent AU-2019355273-A1 (AU)
Title: Multi-valve fluid cartridge
Inventor: COX-MURANAMI WESLEY
IPC: B01L3/00
Filed: 2019-10-02
Abstract: An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.
Patent AU-2019355988-A1 (AU)
Title: Constraining mechanisms for selective deployment and associated methods
Inventor: STASTKA JERRY J
IPC: A61F2/24
Filed: 2019-10-04
Abstract: Various aspects of the present disclosure are directed toward medical device deployment apparatuses, systems, and methods that include a constraint configured to releasably constrain the medical device. The constraint may be unraveled at different rates.
Patent AU-2019356207-A1 (AU)
Title: Genetically modified sterile avians and method for the reconstitution thereof
Inventor: MCGREW MIKE
IPC: C12N15/85
Filed: 2019-10-11
Abstract: Disclosed herein transgene construct comprising (i) a first nucleotide sequence, wherein the activity of the protein encoded by said first nucleotide sequence causes death of germ cells in the presence of an exogenous induction agent and (ii) a second nucleotide sequence which targets said construct to avian germ cells, methods of using the same and a transgenic avian provided by such methods.
Patent AU-2019374750-A1 (AU)
Title: Compositions comprising pyridine carboxylate herbicides with glyphosate or glufosinate
Inventor: SATCHIVI NORBERT M
IPC: A01N57/20
Filed: 2019-11-04
Abstract: Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) glyphosate, glufosinate, an agriculturally acceptable salt thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) glyphosate, glufosinate, an agriculturally acceptable salt thereof, or mixtures thereof.
Patent WO-2021042164-A1 (WO)
Title: Aerosol composition for forming peelable coatings
Inventor: WEST RICHARD
IPC: B01F27/73
Filed: 2020-09-03
Abstract: A quick drying aerosol composition for coating a metal substrate for inhibiting corrosion, wherein droplets of the composition are adapted to be discharged from an aerosol spray device, the aerosol composition comprises: an emulsion of a resin in an amount in the range of 10wt% to 60wt% selected from the group consisting of polyvinyl lower acyl esters in which the acyl has from two to five carbon atoms, poly (lower alkyl) acrylates in which the alkyl has from one to four carbon atoms, poly (lower alkyl) methacrylates in which the alkyl has from one to four carbon atoms, and copolymers thereof; one or more thickening or anti-caking agents in amount in the range of 0.5wt% to 7wt%; a plasticizer in an amount in the range of 1wt% to 15wt% compatible with the resin; and a non-aqueous carrier/solvent in an amount 5wt% to 35wt%.
Patent WO-2021127726-A1 (WO)
Inventor: ANAND VIJAYAKUMAR
IPC: G06T5/00
Filed: 2020-12-21
Abstract: Described herein is an apparatus, system and method of digital imaging. One embodiment provides an apparatus (104) for coupling to a computational device (106) to facilitate digital imaging of an object (102). The apparatus (104) comprises a mask (112) defining an array of pinholes for modulating light (114) diffracted from the object (102). An intensity pattern (120) generated by modulated light (122) from the mask (112) is detectable using an image sensor (124) for digital construction of one or more images of the object (102) by the computational device (106).
Patent AU-2020201775-A1 (AU)
Title: A novel RNAi molecule delivery platform based on single-siRNA and shRNA nanocapsules
Inventor: YAN MING
IPC: A61K9/51
Filed: 2020-03-11
Abstract: Novel siRNA and shRNA nanocapsules and delivery methods are disclosed herein. These siRNA and shRNA nanocapsules and delivery methods are highly robust and effective. This invention provides a platform for RNAi delivery with low toxicity and long intracellular half-life for practical therapeutic applications.
Patent AU-2020205753-A1 (AU)
Title: Methods and compositions for treating cancer
Inventor: CICIRELLI MICHAEL
IPC: C07K14/54
Filed: 2020-01-10
Abstract: This disclosure is directed to compounds, compositions, and methods for the treatment of various diseases and/or conditions related to G protein-coupled receptor 174 (e.g., cancers).
Patent AU-2020214812-A1 (AU)
Title: Anti-IL2 receptor gamma antigen-binding proteins
Inventor: ORENGO JAMIE M
IPC: A61P37/06
Filed: 2020-01-30
Abstract: The present invention provides antibodies and antigen-binding fragments (