baber/WOPTO huggingface dataset:
Patent NZ-232178-A (NZ)
Title: Preparation of insulin precursor
Inventor: DORSCHUG MICHAEL
IPC: C07K1/06
Filed: 1990-01-19
Abstract: An insulin precursor of the formula I <IMAGE>  in which R1 = H, an amino-acid or peptide residue which can be eliminated chemically or enzymatically,  R2 = OH or an amino-acid or peptide residue,  X = a radical joining the insulin A and B chain,  Y = residue of a genetically encodable amino acid,  Z = residue of a genetically encodable amino acid, A1-A20 and B1-B29 = insulin peptide sequences which are non-mutated or mutated by exchange of one or more amino acids, is prepared by reacting a precursor in which the disulphide bridges between positions A6 and A11, A7 and B7, and A20 and B19, have not yet been formed, with excess mercaptan in the presence of an organic redox system or at least one organic compound which forms such an organic redox system under the reaction conditions. The particularly preferred organic redox system is the pair of compounds ascorbic acid + dehydroascorbic acid. The insulin precursor of the formula I can be converted into insulin either enzymatically or chemically by known techniques.
Patent NZ-242863-A (NZ)
Title: Pharmaceutical compositions comprising atipamezole[4-(2-ethyl-2,3-dihydro-1h-inden-2-yl)-1h-imidazole]
Inventor: PERTOVAARA ANTTI
IPC: A61K31/4164
Filed: 1992-05-22
Abstract: This invention concerns the use of atipamezole or a pharmaceutically acceptable acid addition salt thereof for the treatment of male sexual impotence.
Patent NZ-259333-A (NZ)
Title: Pharmaceutical preparations; stable aqueous preparations of g-gsf containing at least one selected buffer
Inventor: WINTER GERHARD
IPC: A61K9/19
Filed: 1993-12-15
Abstract: Aqueous pharmaceutical preparations of G-CSF are disclosed that are stable on storage and a buffer selected from the group consisting of a salt of citrate, maleate, a combination of phosphate and citrate, and arginine; and at least one surfactant.
Patent NZ-264842-A (NZ)
Title: Apparatus and method for joining plastics elements, typically to assemble pipe t or y branch assemblies
Inventor: WULFF FREDERIK KAREL ALBERT
IPC: F16L47/00
Filed: 1994-11-01
Abstract: A method for jointing at least two plastic elements (1-1,2-1), whereby an edge (18) of a first plastic element (1-1) is at least partially placed in an opening of a second plastic element (2-1), the edge (18) of the first plastic element (1-1) being folded over an edge (3) of the opening of the second plastic element (2-1) under plastic deformation, using pressure means (12), whereby the edge of the first plastic element is pressed against a curved butting face of a pressure body being placed in the second plastic element at the opening thereof, that the edge of the first plastic element along the butting face is pushed radially outward and over the edge of the opening of the second plastic element, that the edges of both plastic elements are pressed together by exerting pressure on both sides of the edges, and that use is made of a sealing ring at least partially between the edges. <IMAGE>
Patent NZ-299885-A (NZ)
Title: Propellant actuated sealing plug driving gun has a radially acting ball brake which drives the ball radially towards the driving plunger
Inventor: ALMERAS ROLAND
IPC: B25C1/14
Filed: 1996-12-05
Abstract: After driving a plug and sealing it, the plunger (13) is returned rearwardly to the firing position. There is a brake arranged so as to brake the plunger only when it slides in one direction and including at least one braking ball mounted in a recess of the plug guide and arranged so as to be driven radially towards the plunger. It cooperates with the plunger, when it slides in the braking direction. The braking devices are arranged to drive the ball radially towards the plunger upon application of the device and rearward sliding of the plug guide.
Patent NZ-306096-A (NZ)
Title: System and method for commercial payments using trusted agents
Inventor: ROSEN SHOLOM S
IPC: G06Q20/02
Filed: 1996-03-22
Abstract: An electronic transition device for commercial payments has a host processor with an electronic module. The host processor supports communications external to the transaction device as well as communications to the electronic module, to a transaction application, and to a human/machine interface. The electronic module has a processor which supports communications with the host processor, a transaction protocol, crytography means, and a memory for storing electronic money and tickets. The module executes the transaction protocol and provides remittance advice information to another transaction device after which the first electronic module receives commercial payment ticket from the other transaction device. After that, the electronic module transfers electronic money to the other transaction device. <IMAGE>
Patent NZ-312662-A (NZ)
Title: Pharmaceutical aerosol preparations in the form of stable ethanolic solutions of active substances for producing propellant free aerosols
Inventor: FREUND BERNHARD
IPC: A61L9/04
Filed: 1996-06-21
Abstract: A propellant-free pharmaceutical preparation for the production of propellant-free inhalable aerosols which comprises a pharmacologically active substance other than nitroglycerine or beclomethasone 17,21 dipropionate dissolved in a solvent containing at least 70% (v/v) ethanol.
Patent NZ-313751-A (NZ)
Title: Prolylendopeptidase (PEP) inhibitors, preparation and use thereof
Inventor: KANAI KAROLY
IPC: A61K31/498
Filed: 1996-07-26
Abstract: compound of formula A-B-C-D-L or isomers, epimers, tautomers, salts and prodrugs thereof is claimed wherein: A is a bicyclic heterocyclic ring system as defined in the specification or A is R-Y-N= or R-Y-N(R9)- group; B is -(CH2)m-CO-, -O-(CH2)m-CO-, -C(R12)(R9)-[C(R10)(R13)]w-C(R11)(R14)-CO- or phenyl, phenoxy, arylalkoxy or arylalkyl; C is prolyl or a pyrrolyl, thiazolyl or a bicyclic nitrogen containing ring system as defined in the specification or has the same meaning as D or L; D is a covalent bond, prolyl or thioprolyl or a pyrrolyl or thiazolyl group as defined in the specification and L is pyrrolidino, 2-cyanopyrrolidino, thiazolidino or 2-cyanothiazolidino or an optionally halogen substituted piperidino or a thiazolyl or oxazolyl ring system as defined in the specification and the rest of the variables are as defined in the specification. A pharmaceutical composition containing a compound of formula I as defined above useful in the treatment of CNS diseases is claimed.
Patent NZ-329383-A (NZ)
Title: liquid composition containing at least one carrier and an insoluble magnesium compound
Inventor: FLEMING DAVID
IPC: A61K33/06
Filed: 1997-12-08
Abstract: The liquid composition contains an insoluble magnesium compound having a mean particle size of 7.5mm or less and a carrier. The composition can be used as an additive in a foodstuff, silage, drinking water or a fertilizer or plant food.
Patent NZ-330458-A (NZ)
Title: Production of paper filled with precipitated calcium carbonate or slurries thereof
Inventor: DEPASQUALE DAVID
IPC: D21H17/67
Filed: 1997-02-12
Abstract: Filled paper is made by: 1. adding a cationising amount of cationic polymer to a slurry of precipitated calcium carbonate, 2. mixing this slurry into a celulosic suspension and forming a thin stock, 3. adding anionic particulate material to the suspension before or after the slurry, 4. mixing a polymeric retention aid into the thin stock which includes the precipitated calcium carbonate and the anionic particulate material, draining the thin stock on a screen to form a sheet and drying the sheet. A suitable slurry for this purpose is a slurry of 5 to 70 % by weight precipitated calcium carbonate and cationic polymer selected from 0.1 to 1 % cationic starch and 0.01 to 0.3 % of a high charge density, relatively low molecular weight, cationic polymer.
Patent NZ-333998-A (NZ)
Title: Method for reducing expression variability of transgenes in plant cells using DNA constructs comprising insulator elements
Inventor: THOMPSON WILLIAM F
IPC: C12N15/82
Filed: 1997-07-31
Abstract: method of making recombinant plant cells having reduced variability of expression of foreign genes therein is described herein. The method comprises: (a)	providing a plant cell capable of regeneration; and (b)	transforming the plant cell, with a DNA construct comprising an expression cassette, which construct comprises a transcription initiation region, a structural gene positioned downstream from the transcription initiation region and operatively associated therewith, and an insulator (or "boundary element") positioned (i) 5' to the trancrisption initiation region, (ii) 3' to the structural gene, or (iii) both 5' to the transcription initiation region and 3' to the structural gene. DNA constructs useful for carrying out the method and plant cells and plants produced by the method are also disclosed.
Patent NZ-334102-A (NZ)
Title: Device for sharpening blades with cutting plate bolted to tool receptacle which has protective bead
Inventor: PLANKENHORN WOLFGANG
IPC: B24D15/06
Filed: 1997-07-11
Abstract: A device is disclosed for sharpening blades having a hard metal cutting plate (7), known per se, secured to an ergonomically shaped handle (1). A bead (6) is provided to reduce the risk of accidents.
Patent NZ-336628-A (NZ)
Title: Atropisomers of 3-aryl-4(3H)-quinazolinones and their use as AMPA-receptor antagonists
Inventor: WELCH WILLARD MCKOWAN
IPC: C07D239/91
Filed: 1998-02-06
Abstract: Atropisomers of formula (Ia) may be used for treating or preventing a condition selected from cerebral deficits subsequent to or resulting from cardiac bypass surgery and grafting, stroke, cerebral ischemia, spinal cord trauma, head trauma, Alzheimer's Disease, Huntington's Chorea, amyotrophic lateral sclerosis, epilepsy, AIDS-induced dementia, perinatal hypoxia, hypoxia, cardiac arrest, hypoglycemic neuronal damage, opiate tolerance, alcohol and drug addiction withdrawal, idiopathic and drug induced Parkinson's Disease or brain edema, muscular spasms, migraine headaches, urinary incontinence, psychosis, convulsions, chronic or acute pain, ocular damage, retinopathy, retinal neuropathy, tinnitus, anxiety, emesis and tardive dyskinesia. In formula Ia, R2 is a phenyl group of the formula Ph2, a six membered containing heterocycle of formula II or a five membered heterocycle of formula III; R3 is hydrogen, halo, CN, NO2, CF3, alkyl or alkoxy; R5 is alkyl, halo, CF3, alkoxy or alkylthio; and R6, R7 and R8 are hydrogen or halo. Examples of compounds of formula (Ia) include:  (S)-3-(2-chloro-phenyl)-2-[2-(5-diethylaminomethyl-2-fluoro-phenyl)- vinyl]-6-fluoro-3H-quinazolin-4-one; (S)-3-(2-chloro-phenyl)-2-[2-(6-diethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one; (S)-3-(2-chloro-phenyl)-2-[2-(4-diethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one; (S)-3-(2-chloro-phenyl)-2-[2-(6-ethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one; (S)-3-(2-bromo-phenyl)-2-[2-(6-diethylaminomethyl-pyridin-2-yl)-vinyl]-6-fluoro-3H-quinazolin-4-one; (S)-3-(2-chloro-phenyl)-6-fluoro-2-[2-(6-methoxymethyl-pyridin-2-yl)-vinyl]-3H-quinazolin-4-one; (S)-3-(2-chloro-phenyl)-6-fluoro-2-[2-(4-methyl-pyrimidine-2-yI)-vinyl]-3H-quinazolin-4-one; ( S)-3-(2-chloro-phenyl)-6-fluoro-2-{2-[6-(isopropylamino-methyl)-pyridin-2-yl]-ethyl}-3H-quinazolin-4-one; and (S)-6-fluoro-2-[2-(2-methyl-thiazol-4-yl)-vinyl]-3-(2-methyl-phenyl)-3H-quinazolin-4-one.
Patent NZ-501675-A (NZ)
Title: Translucent milk drink having a pH of 5.7 to 7.0 and a percentage transmission of at least 5% prepared by a cation exchange process
Inventor: KELLS BRIAN ASHLEY
IPC: A23C9/18
Filed: 1999-12-09
Abstract: A method of preparing a translucent milk drink with a pH of 5.6-7.0 comprises (a) providing an opaque milk starting material having a pH of 5.7-6.5; (b) contacting at least a portion of the starting material with a cation exchanger until the percentage transmission of the material (when separated from the exchanger) rises to at least 5; (c) optionally mixing the translucent milk sample with another milk sample while retaining the percentage transmission at least 5 % The process can further comprise the step of drying the translucent milk. A translucent milk drink comprises more than 0.5 (w/v) milk protein and/or more than 0.4 (w/v) casein with a pH of 5.7-7.0 and a percentage transmission of at least 5% when measured as defined in the specification optionally in dried form.  A colouring and flavour can be added to the milk drink.  The milk drink may be used as the base for a soft drink, which may be carbonated or effervescent.
Patent NZ-502370-A (NZ)
Title: Guanidine mimics for use as factor Xa inhibitors
Inventor: LAM PATRICK Y
IPC: A61K31/5377
Filed: 1998-06-18
Abstract: A compound of formula (I) or a stereoisomer or pharmaceutically acceptable salt thereof, wherein; ring D is selected from -CH2N=CH-, -CH2CH2N=CH-, a 5-6 membered aromatic system containing from 0-2 heteroatoms selected from the group N, 0, and S; ring D is substituted with 0-2 R, provided that when ring D is unsubstituted, it contains at least one heteroatom; ring E contains 0-2 N atom and is substituted by 0-1 R R is selected from Cl, F, Br, I, OH, C1-3 alkoxy, NH2, NH(C1-3 alkyl), N(C1-3 alkyl)2, CH2NH2, CH2NH(C1-3 alkyl), CH2N(C1-3 alkyl)2, CH2CH2NH2, CH2CH2NH(C1-3 alkyl), and CH2CH2N(C1-3 alkyl)2; and M is i) an optionally substituted 5-membered heterocyclic ring containing up to four heteroatoms selected from N, O & S; or ii) an optionally substituted 6-membered heterocyclic ring containing up to four N atoms; or iii) an optionally substituted 5-membered heterocyclic ring containing 1 or 2 heteroatoms selected from N, O & S; wherein the heterocyclic ring is condensed with a phenyl ring and wherein the ring system attaches to the DE system via an atom on the heterocyclic ring. The compounds are useful as inhibitors of factor Xa.
Patent NZ-503407-A (NZ)
Title: Anilide derivatives useful for treating inflammatory diseases
Inventor: ASTLES PETER CHARLES
IPC: A61P19/02
Filed: 1998-11-02
Abstract: An anilide derivative, its N-oxides, prodrugs or pharmaceutically acceptable salts and solvates thereof has the formula (I) wherein: R1 is hydrogen, halogen, hydroxy, alkyl or alkoxy; X1, X2 and X6 independently are N or CR10 and one of X3, X4 and X5 is CR11 and the others independently are N or CR10; R10 is hydrogen, amino, halogen, hydroxy, alkyl, alkoxy, alkylthio, alkylsulphinyl, nitro, alkylsulphonyl or trifluoromethyl; R11 is a group -L1-Ar1-L2-Y and L1 is a-R2-R3-linkage; R2 is alkylene, alkenylene, or alkynylene and R3 is a bond, cycloalkylene, heteroaryldiyl, heterocycloalkylene, arylene, -C (=Z)-NR4-, -NR4-C(=Z)-, -Z1-, -C(=O)-, -C (=NOR4)-, -NR4-C(=Z)-NR4-, -SO2-NR4-, -NR4-SO2-, -O-C(=O)-, -C(=O)-O-, -NR4-C(=O)-O- or -O-C(=O)-NR4- but excluding compounds where an oxygen, nitrogen or sulphur atom in R3 is attached directly to a carbon to carbon multiple bond in R2; R4 is hydrogen or alkyl and n is 0 to 2; Z is O or S and Z1 is O, S(O)n or NR4; Ar1 is arylene or heteroaryldiyl and L2 represents: a bond; optionally substituted alkylene, alkenylene, alkynylene, cycloalkenyl, cycloalkylene, heteroaryldiyl, heterocycloalkylene or arylene or -[C(=O)-N(R6)-C(R4) (R7)]p-, -Z2-R9-, -C(=O)-CH2-C(=O)-, R9-Z2-R9- or -C(R4)(R8)-[C(=O)-N(R6)-C(R4)(R7)]p-; Z2 is O, S(O)n, NR4, SONR4, C(=O)NR4 or C(=O); and p is 0 to 4; Y is carboxy (or an acid bioisostere) or-C(=O)-NY1Y2 and R5 to R9, Y1 and Y2 are as defined in the specification limited by the exclusions and provisos as listed in the specification. A pharmaceutical composition thereof is useful for treating an inflammatory disease such as asthma.
Patent NZ-509008-A (NZ)
Title: T section building element fixed in cooperating groove with beading
Inventor: DOONAN ROSS
IPC: E06B3/58
Filed: 1999-06-30
Abstract: A releasable joint (1) includes a first member (2) having an elongate generally T-sectioned connecting formation (3) defining opposed securing flanges (4 and 5) respectively. The second part of the joint includes a second member (6) having a corresponding generally elongate undercut channel (8) in a surface (7) thereof defining, at the edge of said channel, two opposing retaining protuberances (9 and 10) respectively. The connecting formation and undercut channel are configured such that the channel (8) is adapted to: (i)	Receive therein from a direction generally transverse to the plane of said surface (7) the generally T-sectioned connecting formation (3) of the first member; and (ii)	(ii) Permit subsequent displacement of the connecting formation within the undercut channel (8) into a locking position wherein removal thereof in a direction transverse to said surface is prevented by said retaining protuberances (9 and 10). In the locking position a receiving groove (12) is simultaneously defined along an edge of said channel immediately adjacent one of the securing flanges (4 or 5). The joint also includes an elongate resilient beading element (13) adapted to be captively retained upon insertion into said receiving groove (12) so as to urge and maintain said connecting formation (3) in the locking position within the undercut channel (8).
Patent NZ-515093-A (NZ)
Title: Method and apparatus for distribution of communication channels to a device for reception of electronic documents
Inventor: SUNDVALL JONAS
IPC: G06Q40/06
Filed: 2000-04-19
Abstract: Communication channels are distributed to a device for receiving electronic documents by filtering an income or internal document to mechanically determine if it is of interest for subscribers to services included in the device and routing accepted documents to all subscribers in an electronic memory belonging to the device who are affected by the document for selecting subscribers.  An own communication channel to a server included in the device, with a link to a form, and that is unique for every selected subscriber is achieved and the channel is simultaneously distributed via a standardized wireless communication technology for advanced services to all selected subscribers with mobile terminals such as WAP phones, for interaction with the standard. The subscriber can accept or reject the channel via the mobile terminal, and if the subscriber accepts the channel, then the unique form linked to the channel is automatically filled in.
Patent NZ-516657-A (NZ)
Title: High speed machine for inserting sheets into envelopes
Inventor: WERNER TODD
IPC: B65D43/26
Filed: 2000-05-17
Abstract: A high speed machine (10) is disclosed that inserts about twelve thousand sheets or stacks of sheets of paper per hour into the same number of envelopes. A first table 12 delivers an elongate horizontal queue of thousands of envelopes to an envelope hopper 32. A second table 16, parallel to the first table 12, includes a plurality of independently-controllable sheet feeders and delivers individual groups of stacked sheets to an envelope insertion station that is transversely spaced apart from the envelope hopper. A third table 30 is disposed transversely to the first two tables and includes the envelope insertion station. Clamps carried by an elongate sprocket chain mounted in the third table sequentially remove envelopes from the bottom of the envelope hopper and pull them past an envelope flap-opening structure to the envelope insertion station where the envelopes are opened by a puff of air. The envelopes are then pulled past a moistening device, an envelope flap-closing device, and a roller that seals the envelopes and ejects them from the third table to a collection station. Pusher members that push the sheets into the envelopes at the envelope insertion station are mounted on a high speed rotary assembly that eliminates the back-and-forth motion of earlier pusher members.
Patent NZ-519734-A (NZ)
Title: Linear motor
Inventor: DUNCAN GERALD DAVID
IPC: F04B31/00
Filed: 2000-06-21
Abstract: Disclosed is a vapour compressor. The compressor includes a piston (11) and a cylinder (9). The piston is made to reciprocate within the cylinder, where the vibrating system of the piston, spring and the pressure of the vapour have a natural frequency, which varies with vapour pressure. Also, a linear brushless DC motor is drivably coupled to the piston and is also connected to a DC power supply. The current provided by the power supply will cause reciprocation of the piston and a resonant system will then drive the piston at the resonant frequency of the vibrating system. The current is control by the current control means and is determined by the resonant frequency.
Patent NZ-521751-A (NZ)
Title: Filter adapted for long lasting biocidal or biostatic activity by applying a water soluable biocidal or biostatic agent and a humectant
Inventor: KRITZLER STEVEN
IPC: B01D27/06
Filed: 2001-03-27
Abstract: The invention relates to an air filter including a composition that has a biostatic or biocidal agent adapted to migrate through particulates accumulating in use on the filter. The biocidal agent may have bacteriostatic and/or fungistatic properties, may include a humectant as a means for assisting the migration of the biostatic or biocidal agent, and may optionally a surfactant or rheological additive. The invention also relates to compositions for treating filters and a method of reducing airborne contaminants in air.
Patent NZ-522498-A (NZ)
Title: Fungicidal combinations of active agents
Inventor: MAULER-MACHNIK ASTRID
IPC: A01N43/08
Filed: 2001-04-30
Abstract: The application relates to novel combinations of active agents, consisting of compounds of formula (I) and known active agents, and to their use for controlling phytopathogenic fungi
Patent NZ-522988-A (NZ)
Title: Anti-theft clamp for a motor cycle hand brake lever
Inventor: CHAPPELL NEILS WILLIAM
IPC: E05B71/00
Filed: 2001-05-08
Abstract: A clamp (40) for preventing theft of a motor cycle,  by disabling operation of a handlebar brake lever comprises:  a pair of jaws (2, 3) connected together at a pivot (4) so  as to  be  movable between an open and a closed condition,  the jaws  (2,  3) providing when in the closed condition,  first and  second substantially parallel apertures (6, 7)  through the  clamp  (40),  the first aperture (6)  being  shaped  to receive  a  handlebar  handgrip  portion  through,  and  the second  aperture (7) being formed in a movable  member  (10) and  positioned  so as to receive a brake  or  clutch  lever mounted  on the handlebar. The clamp (40) also has a locking device  (42)  for enabling the jaws (2, 3) to be  locked  in the  closed condition. The movable member (10) is locked  at optional  positions when the jaws (2, 3) are in  the  closed condition,  by  a  pair of ribs (18), which  engage  into  a series  of  transverse grooves formed in the jaw  (3)  along the length thereof.
Patent NZ-523679-A (NZ)
Title: Process for folding chemically synthesized polypeptides containing derivatised cysteine
Inventor: VERDINI ANTONIO
IPC: C07K1/14
Filed: 2001-11-27
Abstract: A process for folding chemically synthesized polypeptides comprises treating a polypeptide or protein comprising two or more S-butyl-thio-cysteine residues with a reducing agent in a folding buffer having a pH between 7 and 9 at a temperature between 25oC and 40oC.