baber/WOPTO huggingface dataset:
Patent EP-2336177-A1 (EP)
Inventor: LI JI
IPC: A61K39/395
Filed: 2005-08-04
Abstract: The present invention provides antibodies and immunologically functional fragments thereof that specifically bind Dkk-1 polypeptides. The subject antibodies and fragments bind with high affinity to a conformational epitope located in the carboxy region of the Dkk-1 protein. Methods for preparing such antibodies or fragments thereof as well as physiologically acceptable compositions containing the antibodies or fragments are also provided. Use of the antibodies and fragments to treat various diseases including bone disorders, inflammatory diseases, neurological diseases, ocular diseases, renal diseases, pulmonary diseases and skin diseases are also disclosed.
Patent EP-2363435-A1 (EP)
Inventor: BURI MATTHIAS
IPC: C09C1/02
Filed: 2010-01-27
Abstract: Use of at least one polyethylenimine as an additive in an aqueous suspension, containing from 25 to 62 vol. % of at least one calcium carbonate-comprising material, wherein the use provides improved stability with regard to the conductivity of the suspension.
Patent EP-2359982-A1 (EP)
Inventor: WITTERS GILBERT
IPC: A47L11/14
Filed: 2010-02-22
Abstract: The present invention is directed to a floor-treating machine, comprising: a frame (70), a housing (62) attached to the frame (70) and rotatable about a substantially vertical axis, one or more heads (64) mounted in the housing (62) and rotatable about a substantially vertical axis, a motor (50) with a motor shaft (51) for driving a housing shaft (54), said housing shaft (54) connected to the one ore more heads (64) by means of a transmission, an auxiliary shaft (57) for driving the housing (62), characterized in that the auxiliary shaft (57) is connected via a first auxiliary transmission (52, 53, 55, 56) to the housing shaft (54) and via a second auxiliary transmission (58, 59, 60) to the housing (62).
Patent EP-2293372-A1 (EP)
Inventor: TANIGUCHI SHUNSUKE
IPC: H01M8/24
Filed: 2010-03-24
Abstract: There is provided a combined cell structure for a solid oxide fuel cell provided with a structure in which a plurality of tube-type or flat-tube-type solid oxide fuel cell are combined with one another in series in a longitudinal direction. The combined cell structure includes first and second cells each having a first electrode, a second electrode and an electrolyte layer interposed between the first and second electrodes; a first support member for passing through a hollow portion of the first cell; and a second support member for passing through a hollow portion of the second cell. In the combined cell structure, one ends of the first and second support members facing each other are fixedly combined with each other. Accordingly, the first and second cells are connected to each other in the flow direction of a reactant.
Patent EP-2248934-A1 (EP)
Inventor: SEO DONG PIL
IPC: D06F13/06
Filed: 2010-03-26
Abstract: Disclosed herein is a washing machine to generate rotating and vertical water streams simultaneously. The rotating water stream is generated by rotation of an outer pulsator, and the vertical water stream is generated by rotation of an inner pulsator. A rotating body is installed between the outer pulsator and the inner pulsator, to convert rotation into vertical movement. An inner wall of the outer pulsator is formed with a curved surface to come into close contact with the inner pulsator being moved vertically.
Patent EP-2254019-A1 (EP)
Inventor: NITTA KAZUHIRO
IPC: G06F1/20
Filed: 2010-04-30
Abstract: A fan unit includes a housing having an air inlet and an air outlet; a first fan and second fan mounted in the air inlet and the air outlet respectively and arranged in tandem so as to generate an air flow; a first valve mounted adjacent to the air inlet for allowing air to flow into the housing and preventing air from flowing out of the housing; and a second valve mounted adjacent to the air outlet for allowing air to flow out of the housing and preventing air from flowing into the housing.
Patent EP-2255961-A1 (EP)
Inventor: TAN DANIEL QI
IPC: B32B27/20
Filed: 2010-05-14
Abstract: In one aspect of the present invention, an article is described, including a polymer layer; and a composite layer disposed on the polymer layer. The composite layer includes a thermoplastic polymer, which contains at least one inorganic component having selected dimensions; wherein the largest dimension of the inorganic component is less than about 1 micrometer. The composite layer has a dielectric constant, which is at least about 30 percent greater than the dielectric constant of the polymer layer. The article has a breakdown strength of at least about 150 kV/mm. Related devices are also described.
Patent EP-2408260-A1 (EP)
Inventor: CHOLEWA HARALD
IPC: H01R13/11
Filed: 2010-07-13
Abstract: The pane (1) has a substrate made of glass, and an electrical conductive structure (2) provided with thickness of 5 to 40 micrometers in a region of the substrate. A solder mass layer (4) electrically connects a connector (3) with a portion of the structure over a contact area, where the connector contains iron-nickel alloy or iron- nickel-cobalt alloy, and the contact area exhibits no corners. The connector contains iron, nickel, cobalt, magnesium, silicon, carbon or manganese, and the solder mass layer contains tin, bismuth, indium, zinc, copper or silver. An independent claim is also included for a method for manufacturing a pane.
Patent EP-2239275-A1 (EP)
Inventor: HECHT REINHOLD
IPC: C08F2/00
Filed: 2006-05-31
Abstract: This invention relates to polymerizable compositions comprising a salt of a barbituric acid derivative. The compositions are typically shelf-life stable and may be polymerized through mixing of an acidic component with the salt of a barbituric acid derivative.
Patent EP-2309005-A1 (EP)
Inventor: LEWIN JOERN
IPC: C12Q1/68
Filed: 2010-08-02
Abstract: The present invention relates to methods and kits for preserving genomic DNA sequence complexity within chemically and/or enzymatically converted DNA by an enzyme or series of enzymes that adds a methyl group to a cytosine outside of CpG dinucleotide sequences of genomic DNA. Further, the present invention relates to methylation analysis of the genomic DNA.
Patent EP-2385138-A1 (EP)
Inventor: LENZ HEINZ-JOSEF
IPC: C12Q1/68
Filed: 2003-07-31
Abstract: The invention provides compositions and methods for determining the increased risk for recurrence of certain cancers and the likelihood of successful treatment with one or both of chemotherapy and radiation therapy. The methods comprising determining the type of genomic polymorphism present in a predetermined region of the gene of interest isolated from the subject or patient. Also provided are nucleic acid probes and kits for determining a patient's cancer risk and treatment response.
Patent EP-2322078-A1 (EP)
Inventor: ROOT THOMAS V
IPC: G06Q30/04
Filed: 2003-03-18
Abstract: Reusable instruments, such as reusable medical instruments, and related systems and methods, are disclosed. In some embodiments, the reusable instrument can be an endoscope.
Patent EP-2362612-A1 (EP)
Inventor: SPOTO JAY ROBERT
IPC: H01Q1/24
Filed: 2010-11-10
Abstract: A portable electronic device (200), having a rear housing (204), an upper housing (202) coupled to the rear housing (204) and slideable relative thereto between a closed position and an open position, an antenna (230), and at least one element (240,242) coupled to the antenna (230) and configured to perform at least one of inhibiting low frequency shift and increasing high frequency sensitivity of the antenna (230).
Patent EP-2407536-A1 (EP)
Inventor: MCKERRACHER LISA
IPC: C07K19/00
Filed: 2007-12-12
Abstract: The present invention relates to a polypeptide, pharmaceutical compositions comprising said polypeptide and their use for the treatment of spinal cord injuries, neurological or neurodegenerative diseases or other nerve system damage, macular degeneration or for treating or preventing cancer.
Patent EP-2256913-A1 (EP)
Inventor: LU HUANYU
IPC: H02M3/335
Filed: 2010-05-27
Abstract: A switching power supply such as e.g. a flyback converter has an inductor that includes a coil. A chopper circuit chops the primary current drawn through the coil, for the inductor to output an induced current. A multifunction junction of the power supply has a multifunction voltage that is a function of a primary voltage that drives the coil. A first circuit suspends the chopping in response to a first sensed voltage crossing a first threshold, the first sensed voltage being a function of the multifunction voltage. A second circuit suspends the chopping in response to a second sensed voltage crossing a second threshold, the second threshold being a function of the multifunction voltage.
Patent EP-2387996-A1 (EP)
IPC: A61K31/343
Filed: 2010-05-17
Abstract: Use of dronedarone for the preparation of a medicament for the prevention of cardiovascular events notably stroke, acute coronary syndrome or cardiovascular death in patients with permanent atrial fibrillation.
Patent EP-2394637-A1 (EP)
Inventor: MALGORZATA STOKROCKA
IPC: A61K9/00
Filed: 2010-05-21
Abstract: The invention relates to methods of manufacturing pharmaceutical suspensions comprising brinzolamide sterilized by gamma irradiation or ethylene oxide, to compositions obtainable by this process and to the use of brinzolamide thus sterilized for the preparation of sterile ophthalmic composition. The invention further relates to pharmaceutical compositions of brinzolamide comprising less than 0.1% of chiral impurity of brinzolamide.
Patent EP-2393698-A1 (EP)
Inventor: VOITH ANDRAS
IPC: B60T15/02
Filed: 2010-01-14
Abstract: Kolbenventil (10), insbesondere für eine pneumatische Bremsanlage eines Fahrzeugs, mit einem in einem Bereich (12) eines Gehäuses (14) in einer axialen Richtung (16) beweglichen Schaltkolben (18), zumindest zwei Anschlüssen (20, 22), die in einer ersten Schaltstellung des Schaltkolbens (18) miteinander gekoppelt sind, und einem Dichtelement (24), das eine Verbindung (38) zwischen den zumindest zwei Anschlüssen (20, 22) in zumindest einer zweiten Schaltstellung des Schaltkolbens (18) abdichtet. Erfindungsgemäß ist vorgesehen, dass das Dichtelement (24) als Nutring mit einer flexiblen Dichtlippe (26) ausgeführt ist, die als Rückschlagventil zwischen den zumindest zwei Anschlüssen (20, 22) arbeitet.
Patent EP-2417254-A1 (EP)
Inventor: ESTABROOK MELODIE
IPC: C12N9/28
Filed: 2010-02-25
Abstract: Compositions and methods relating to an alpha-amylase enzyme obtained from Halomonas variabilis WDG195 are described.
Patent EP-2254714-A1 (EP)
Inventor: HOLSCHER WINFRIED K W
IPC: B21K1/70
Filed: 2010-01-20
Abstract: L'invention concerne un procédé utilisé pour produire un élément taraudé (1) présentant un premier segment (20) et un second segment (21) qui est positionné par rapport au premier segment de sorte à produire un couple de freinage lors de l'assemblage par vissage des deux segments taraudés (20, 21) avec un élément fileté (19). L'invention concerne en outre un élément taraudé (1) et un assemblage par vissage.
Patent EP-2411578-A1 (EP)
Inventor: Nägeli ivo
IPC: D21H17/14
Filed: 2010-03-19
Abstract: The invention relates to a method for feeding a deaerating /defoaming agent into a process liquid, especially in a paper machine. The invention also relates to a device for carrying out said method. The method is characterised in that the agent, which has a melting point of less than 40°C, is emulsified in water, in situ, that is typically directly next to the paper machine or close to a container/line guiding the process liquid, by means of at least one mixing element (7), and is fed into the process liquid less than 24 hours, preferably less than 3 hours, or even less than 30 minutes, after the emulsifying process.
Patent EP-2435785-A1 (EP)
Title: Aiming optical device
Inventor: SINNER-HETTENBACH MARTIN
IPC: G01S17/08
Filed: 2010-03-29
Abstract: The invention is based on an aiming optical device for a measuring instrument, more particularly for a distance measuring instrument (12; 12a) comprising an optical unit (14; 14a), having at least one optical deflection unit (16; 16a) and a first optical lens element (18; 18a). It is proposed that the optical deflection unit (16; 16a) and the first optical lens element (18, 18a) are embodied integrally with one another at least in part.
Patent EP-2419452-A1 (EP)
Inventor: REES ANTHONY
IPC: A61K47/48
Filed: 2010-04-09
Abstract: The present application relates to an affinity material useful in antibody purification.
Patent EP-2416984-A1 (EP)
Title: Elektrofahrzeug mit gps gestützter tankstellenreservierung
Inventor: SCHAEFER TIM
IPC: B60L50/15
Filed: 2010-03-31
Abstract: Verfahren zum Betreiben eines Fahrzeugs, welches einen elektrischen Fahrantrieb und wenigstens eine wiederaufladbare und austauschbare Elektroenergieeinheit aufweist, wobei dem elektrischen Fahrantrieb elektrische Antriebsenergie von der Elektroenergieeinheit zugeführt wird und wobei die Elektroenergieeinheit bei niedrigem Ladezustand aufgeladen oder ausgetauscht wird.
Patent EP-2430021-A1 (EP)
Inventor: CID-NUNEZ JOSE MARIA
IPC: A61K31/445
Filed: 2010-05-11
Abstract: The present invention relates to novel triazolo[4,3-a]pyridine derivatives of Formula (I) wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2"), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.
Patent EP-2438445-A1 (EP)
Title: Moyen et procédés de diagnostic de carcinomes de prostate
Inventor: KAMLAGE BEATE
IPC: G01N33/574
Filed: 2010-06-02
Abstract: La présente invention porte sur un procédé, de préférence un procédé ex vivo, de diagnostic de carcinomes de la prostate et/ou de prédispositions à celui-ci, comprenant la détermination d'au moins un métabolite dans un échantillon de test d'un sujet qu'on suspecte souffrir d'un carcinome de la prostate ou avoir une prédisposition à celui-ci et la comparaison dudit au moins un métabolite à une référence, grâce à quoi on peut diagnostiquer des carcinomes de la prostate ou une prédisposition à celui-ci. De plus, la présente invention porte sur la collecte de métabolites, sur une collecte de données comprenant les valeurs caractéristiques de métabolites et un milieu de mémorisation comprenant lesdites collectes de données. De plus, la présente invention porte également sur un système comprenant des moyens de comparaison des valeurs caractéristiques de métabolites d'un échantillon lié en fonctionnement à un milieu de mémorisation de données. L'invention porte en outre sur un moyen de diagnostic comprenant au moins un métabolite et sur l'utilisation dudit au moins un métabolite pour la fabrication d'un moyen de diagnostic pour le diagnostic d'un carcinome de prostate. Enfin, la présente invention porte sur un procédé d'identification de métabolites associés à un carcinome de la prostate.
Patent EP-2452478-A1 (EP)
Inventor: GALLAS FREDERIC
IPC: G06F21/44
Filed: 2010-06-24
Abstract: The invention is a method of managing an application embedded in a secured electronic token. The token is intended to receive a message from a server machine. The message has a header and a body. The token comprises an agent able to manage the message. The method comprises the steps of : a) registering the application in the agent by associating a reference of the application with a value of an element of the message header; b) when the message is received from the server machine, forwarding part of the message to the application if the message header contains an element having the value associated to the reference of the application.
Patent EP-2446319-A1 (EP)
Inventor: COLLINS MICHAEL
IPC: G02C7/02
Filed: 2010-06-23
Abstract: Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.
Patent EP-2390910-A1 (EP)
Inventor: KAWABATA KAZUHIRO
IPC: H01L23/36
Filed: 2010-01-22
Abstract: There are provided a substrate for mounting a device and a package for housing the device employing the same in which a power semiconductor device can be readily set for a temperature suitable for operation and can thus function in a proper fashion. 
     [Solution] The substrate for mounting the device includes a support body (3) having, on one main surface (31a) of the support body (3), a device mounting portion (31) for mounting a power semiconductor device (4), the support body (3) having a plurality of columnar parts (32) that are spaced apart in a thickness direction with respect to the device mounting portion (31) and are arranged apart from each other; and a heat accumulating region which is disposed between the columnar parts (32) and is lower in thermal conductivity than the support body (3).
Patent EP-2390768-A1 (EP)
Inventor: SHIOIRI KENTA
IPC: G06F3/0489
Filed: 2010-01-15
Abstract: When a detecting unit detects an operation of a key which is not included in a combination predicted by a prediction unit, an input control unit invalidates the operation of the key. Therefore, even if a user wrongly presses a key, the wrong pressing is invalidated, as a result key input intended by the user becomes smooth.
Patent EP-2389439-A1 (EP)
Inventor: LIU JIANJUN
IPC: C12Q1/68
Filed: 2010-01-22
Abstract: The present invention relates to single nucleotide polymorphism (SNP). In particular, it relates to a SNP within an intronic p53 binding motif of the PRKAG2. Nucleic acid molecules and methods for aiding assessment of a patient's risk of developing cancer by determining the patient's genotype for a p53 binding motif within the PRKAG2 gene are included in the present invention.
Patent EP-2437760-A1 (EP)
Inventor: ROMMELAERE JEAN
IPC: A61K35/768
Filed: 2010-05-19
Abstract: Le parvovirus ci-décrit permet de prévenir la récidive d'une tumeur, de préférence, une tumeur maligne du cerveau ou une tumeur du pancréas.
Patent EP-2396263-A1 (EP)
Title: Tableau d'appel
Inventor: POUTIAINEN VESA
IPC: B66B1/46
Filed: 2010-02-16
Abstract: La présente invention présente un tableau d'appel d'un ascenseur ou d'un système d'élévation, ledit tableau d'appel comprenant un ou plusieurs éléments d'affichage (10), une plaque avant (12) recouvrant le tableau d'appel, un capteur tactile (11) installé en liaison avec ladite plaque avant, et également une unité de commande (13) à laquelle les éléments d'affichage ainsi que le capteur tactile sont reliés. La zone de détection (21) du capteur tactile comprend des zones actives (23) recouvertes par les éléments d'affichage ainsi qu'une zone passive qui reste à l'extérieur d'au moins certaines des zones actives précitées (23), un ou plusieurs boutons-poussoirs sensibles au toucher (24) étant spécifiés pour ladite zone passive. L'unité de commande (13) est conçue pour réagir à un toucher sur les boutons-poussoirs sensibles au toucher (24, 25) spécifiés pour la zone de détection précitée (21).
Patent EP-2465166-A1 (EP)
Inventor: WORLEY ANDREW
IPC: H01R35/04
Filed: 2010-08-06
Abstract: L'invention porte sur une charnière (4) destinée à une unité de système de distribution électrique d'avion (1), laquelle charnière comprend un premier élément de charnière (11) pour connexion à une première partie de boîtier (3) de l'unité, et un second élément de charnière (10) pour connexion à une seconde partie de boîtier (2) de l'unité. Les premier (11) et second (10) éléments de charnière comprennent un matériau électriquement conducteur et peuvent être connectés l'un à l'autre afin d'établir une connexion électrique entre les éléments de charnière (10, 11) et de permettre une rotation relative entre les éléments de charnière.
Patent EP-2403402-A1 (EP)
Inventor: JESTER STEVEN J
IPC: G01R33/28
Filed: 2010-03-04
Abstract: A temperature monitoring system for a medical device comprises an optical transmit/receive unit, an elongate optical fiber having a proximal end, a distal end, and an inner core extending between the proximal end and the distal end, and one or more fiber Bragg grating elements formed in the inner core of the optical fiber. The optical fiber is operably coupled to the transmit/receive unit at the proximal end. At least a portion of the optical fiber is also operably coupled to a medical device and is structured to measure temperature at one or more temperature sensing locations on the medical device.
Patent EP-2504203-A1 (EP)
Title: Sicherungsvorrichtung und verfahren zur verhinderung einer unbefugten inbetriebnahme eines fahrzeuges
Inventor: REDTEL HOLGER
IPC: B62H5/06
Filed: 2010-07-10
Abstract: Die Erfindung betrifft eine Sicherungsvorrichtung (1) zur Verhinderung einer unbefugten Inbetriebnahme eines Fahrzeuges, mindestens eine Steuerung, mindestens einen Aktor (9) und mindestens zwei die Bewegung eines Fahrzeuges beeinflussende Bauteile enthaltend, bei der mittels des Aktors (9) eine reversible Verbindung zwischen den die Bewegung eines Fahrzeuges beeinflussenden Bauteilen herstellbar oder lösbar ist, wobei der Aktor (9) mit der Steuerung bedienbar ist und wobei der Aktor (9) und die die Bewegung eines Fahrzeuges beeinflussenden Bauteile vollständig oder teilweise in einem Gehäuse (7) angeordnet sind. Ferner werden ein Verfahren zur Sicherung eines Fahrzeuges mit der Sicherungsvorrichtung (1) und die Verwendung der Sicherungsvorrichtung (1) beschrieben.
Patent EP-2411004-A1 (EP)
Inventor: WONG WAI SHIU FRED
IPC: A61K31/19
Filed: 2010-03-24
Abstract: We describe for the first time that andrographolide dirivatives such as DDAG effectively reduced OVA-induced inflammatory cell recruitment into BAL fluid, IL-4, IL-5, IL-13 and eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion and AHR in a mouse asthma model potentially via inhibition of NF-?B activity. Moreover, low dose of DDAG and glucocorticoid combination treatment synergistically attenuate inflammation in mouse asthma model. These findings support a therapeutic value for DDAG in the treatment of asthma.
Patent EP-2411051-A1 (EP)
Inventor: RUBENSTEIN RICHARD
IPC: G01N33/53
Filed: 2010-03-25
Abstract: Methods for detection of the presence or absence of PrP Sc  in a biological sample suspected of having them comprising the steps of concentrating the PrP Sc  as may be present in the sample by substantially separating the PrP Sc  from the sample matrix; labeling the concentrated PrP Sc  with at least one molecular label to produce labeled PrP Sc ; and detecting the labeled PrP Sc  on an instrument capable of detecting an attomole quantity of labeled PrP Sc , and wherein the duration of time between concentrating the PrP Sc  and analyzing the labeled PrP Sc  is about 48 hours or less.