baber/WOPTO huggingface dataset:
Patent CA-3009527-A1 (CA)
Title: Methods of treating cancer
Inventor: WILLINGHAM STEPHEN
IPC: A61K31/47
Filed: 2016-12-22
Abstract: Provided herein are, inter alia, methods of treating cancer by administering to a subject a therapeutically effective amount of an adenosine-A2A(A2A) receptor antagonist or a combination of an adenosine-A2A(A2A)receptor antagonist and a programmed cell death protein 1(PD-1) signaling pathway inhibitor. Further provided are pharmaceutical compositions including an A2Areceptor antagonist, a PD-1 signaling pathway inhibitor and a pharmaceutically acceptable excipient. Further provided are methods of detecting cellular effects,for example expression of pCREB, before, after or during adenosine receptor antagonist treatment.
Patent CA-3011690-A1 (CA)
Title: Appareil et methode pour transferer des articles en mouvement continu a des emballages en mouvement continu comprenant un groupement d'article intervenant et ajustement de l'inclinaison du groupe
Inventor: KALANY ROBERT M
IPC: B65B57/14
Filed: 2017-01-13
Abstract: L'invention concerne un appareil et des procédés d'emballage, lesquels mettent en uvre une pluralité de dispositifs de saisie d'articles (20-26) entraînés par des moteurs commandés indépendamment (8) dans un outillage de fin de bras (EOAT) (10), pour saisir des articles (40), grouper des articles (40), régler le pas des groupes et disposer des groupes d'articles dans des emballages (48) où des articles entrants (10) et des emballages (48) se déplacent de façon continue ou intermittente et sans déplacement de la totalité de l'outillage de fin de bras (10) dans la direction dans laquelle les articles et les emballages sont saisis et déplacés. L'invention concerne également un appareil et des procédés de réparation de trou et d'alignement de produits entrants.
Patent CA-3012042-A1 (CA)
Inventor: BREUNIG JOSHUA
IPC: C12N15/85
Filed: 2016-12-30
Abstract: La présente invention concerne des vecteurs et des systèmes donneurs destinés à être utilisés pour l'échange de cassettes à médiation par recombinase double in vivo. L'invention concerne également des modèles animaux permettant une étude cohérente, rigoureuse et aisée de l'expression de transgènes. L'invention concerne en outre des méthodes de criblage de médicaments thérapeutiques utilisant ces modèles animaux, et des méthodes de traitement.
Patent CA-3015665-A1 (CA)
Title: Crispr/cas systems for c1-fixing bacteria
Inventor: NAGARAJU SHILPA
IPC: C12N15/74
Filed: 2017-02-25
Abstract: The invention provides methods of genetically engineering a C1-fixing bacterium using a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) (CRISPR/Cas) system. Preferably, the Cas protein is under the control of an inducible promoter.
Patent CA-3016417-A1 (CA)
Title: Systeme, procede et filtre de ventilation
Inventor: LEKEBERG NILS
IPC: B01D49/00
Filed: 2017-03-01
Abstract: Système de ventilation (1) configuré pour être autonettoyant, où ledit système de ventilation (1) comprend : une unité de filtration (3) configurée pour filtrer l'air d'échappement guidé à travers celle-ci par au moins un conduit d'air (2, 5, 17) ; une chambre de condensation (6a) configurée pour collecter de l'eau de condensation à partir de l'air d'échappement ; un élément de chauffage (13) configuré pour chauffer l'eau de condensation jusqu'à une température égale ou supérieure à 65 degrés Celsius ; et un système d'extincteur (16a-e) configuré pour pulvériser l'eau de condensation dans une ou plusieurs des unités de filtration (3), au moins l'un du ou des conduits d'air (2, 5, 17), et/ou la chambre de condensation (6a), où le système de ventilation (1) est ainsi configuré pour mettre en uvre un autonettoyage du système de ventilation à l'aide de l'eau de condensation.
Patent CA-3017693-A1 (CA)
Inventor: HERMANS PETER
IPC: H01B5/10
Filed: 2017-03-14
Abstract: L'invention concerne un procédé de positionnement d'un conducteur pour un transport d'énergie aérien, l'obtention d'un conducteur avec une âme allongée et une gaine allongée située autour de l'âme allongée. Le procédé comprend l'étape consistant à fixer la gaine allongée sur l'âme allongée dans une position qui n'est pas située aux extrémités du conducteur, à l'aide d'au moins une pièce de serrage.
Patent CA-3019360-A1 (CA)
Title: Method for sending sync beacon message by nan device, and device
Inventor: PANG GAOKUN
IPC: H04W56/00
Filed: 2016-03-28
Abstract: Embodiments of the present invention relate to the communications field, and provide a method for sending a sync beacon message by a NAN device, and a device, so as to resolve a problem of a sync beacon message conflict that occurs when the NAN device merges to a new cluster in a master role. The method is: when a first device in a first cluster receives first cluster information of a second cluster, if the first device determines to merge to the second cluster, sending a sync beacon message in the second cluster according to a role and a state of the first device in the first cluster. According to the embodiments of the present invention, after merging to a cluster, a NAN device determines whether to send a sync beacon frame.
Patent CA-3021072-A1 (CA)
Inventor: PETERSON BENJAMIN JAMES
IPC: F04D29/66
Filed: 2017-04-20
Abstract: An air blower has an inlet muffler and an outlet muffler to reduce the noise of the air blower during operation. Each of the mufflers may have two sections. One section is configured to attenuate high frequency noise and the other section is configured to attenuate lower frequency noise. A tubular internal wall in each of the mufflers defines the through passage for each of the mufflers. A noise absorbent material may be fitted about the tubular wall within each muffler. A plurality of holes are formed along the tubular wall of each through passage to expose the through passage to the noise absorbent material. A heater plenum may be interposed between the blower plenum and the outlet muffler to heat the air from the blower plenum. A filter at the input muffler filters the air sucked into the air blower.
Patent CA-3022526-A1 (CA)
Inventor: HANSON ARIEL DAWN
IPC: C12N5/00
Filed: 2017-05-05
Abstract: The present disclosure provides methods for producing bioengineered tissue along apparatus and other relevant compositions employed in generation thereof.
Patent CA-3023069-A1 (CA)
Title: Wireless power transfer system
Inventor: MITCHESON PAUL
IPC: H02J50/12
Filed: 2017-05-04
Abstract: A power inverter is disclosed herein. The power inverter is suitable for driving a transmitter coil in an inductive power transfer system, wherein the inverter is suitable for class 'EF' operation. The inverter is arranged to drive a load resistance, and comprises a switching device arranged between a power source and ground and arranged to switch at a switching frequency. The inverter also comprises a resonant network arranged in parallel with the switching device between the power source and ground, the resonant network having a resonant frequency which is a non-integer multiple of the switching frequency, such that, in operation, a substantially constant current passes through the load resistance.
Patent CA-3023335-A1 (CA)
Inventor: MUELLER CHRISTOPHER ROBERT
IPC: G01N33/48
Filed: 2017-05-04
Abstract: Provided herein is a method for detecting a tumour that can be applied to cell-free samples, e.g., to cell-free detect circulating tumour DNA. The method utilizes detection of adjacent methylation signals within a single sequencing read as the basic positive tumour signal, thereby decreasing false positives. The method comprises extracting DNA from a cell-free sample obtained from a subject, bisulphite converting the DNA, amplifying regions methylated in cancer (e.g., CpG islands, CpG shores, and/or CpG shelves), generating sequencing reads, and detecting tumour signals. To increase sensitivity, biased primers designed based on bisulphite converted methylated sequences can be used. Target methylated regions can be selected from a pre-validated set according to the specific aim of the test. Absolute number, proportion, and/or distribution of tumour signals may be used for tumour detection or classification. The method is also useful in, e.g., predicting, prognosticating, and/or monitoring response to treatment, tumour load, relapse, cancer development, or risk.
Patent CA-3024786-A1 (CA)
Inventor: ZHAO YIMING
IPC: G05B19/02
Filed: 2016-07-29
Abstract: A method includes generating a torsional wave that propagates in a drill string having a drill bit coupled at a first end of the drill string and a top drive coupled at a second end of the drill string, and determining first and second components of the torsional wave. The first component propagates from the drill bit to the top drive and the second component propagates from the top drive to the drill bit. The method further includes calculating a first control signal to mitigate the first component, calculating a second control signal to regulate the second component, and generating a torque command based on the first and second control signals to control the top drive to dampen the torsional wave.
Patent CA-3025422-A1 (CA)
Inventor: HUTTON SAMUEL HARRISON
IPC: G06F21/56
Filed: 2017-06-06
Abstract: A Threat Intelligence Cloud is disclosed. The Threat Intelligence Cloud can include a machine. A receiver on the machine can receive an electronic file including a threat detected by an anti-virus solution. A Virus Total Service can determine information from traditional anti-virus solutions scanning the electronic file. A database can store the information from the Virus Total Service. A report generator can generate a report from the information.
Patent CA-3027552-A1 (CA)
Inventor: ZHENG JIANFENG
IPC: G08G1/08
Filed: 2018-10-16
Abstract: Embodiments of the disclosure provide systems and methods for optimizing a traffic control plan. The system may include at least one storage device configured to store instructions and at least one processor configured to execute the instructions to perform operations. The operations may include receiving traffic system log data and parsing the traffic system log data to obtain a first set of traffic performance parameters. The operations may also include receiving trajectory data relating to a plurality of vehicle movements and parsing the trajectory data to obtain a second set of traffic performance parameters. The operations may further include determining relationships between vehicle delays and degrees of saturation based on the first and second sets of traffic performance parameters. In addition, the operations may include optimizing the traffic control plan based on the relationships.
Patent CA-3028312-A1 (CA)
Title: Pneumatic control valve manifold
Inventor: JAMISON MICHAEL
IPC: F16K31/06
Filed: 2018-12-20
Abstract: A pneumatic control valve manifold assembly including a modular manifold segment with first and second valve receiving bores, inlet and exhaust cavities, and fluid passageways. The modular manifold segment has a mating face and a back-side face. The fluid passageways are arranged in fluid communication with the first and second valve receiving bores, are open to the modular manifold segment mating face, and have multiple configurations. The modular manifold segment mating face includes an abutment surface surrounding the fluid passageways that has a plurality of shapes depending upon the configuration of the fluid passageways. The modular manifold segment back-side face includes a plurality of sealing ribs arranged in a pattern that universally mates with each of the different shapes of the abutment surface such that multiple modular manifold segments with different fluid passageways can be stacked next to each other. L'invention concerne un procédé de modélisation d'un bassin sédimentaire, ledit bassin sédimentaire ayant subi une pluralité d'événements géologiques définissant une séquence d'états (A i) du bassin chacun s'étendant entre deux événements géologiques successifs, le procédé comprenant la mise en ceuvre par des moyens de traitement de données (21) d'étapes de : (a) Obtention de mesures de grandeurs physiques dudit bassin acquises depuis des capteurs (20) ; (b) Pour chacun desdits états A i, construction d'une représentation maillée du bassin en fonction desdites mesures de grandeurs physiques ; (c) Pour chacun desdits états A i, et pour chaque maille de la représentation maillée, 1. calcul d'une contrainte effective appliquée sur la maille à la fin de l'état A i ; 2. calcul d'une surpression dans la maille à la fin de l'état A ien fonction de ladite contrainte effective calculée à la fin de l'état A i.
Patent CA-3028765-A1 (CA)
Title: Heat recovery apparatus and method
Inventor: GIL VICENTE
IPC: E03C1/00
Filed: 2019-01-02
Abstract: A grey water heat recovery apparatus has first and second passes in counter-flow orientation. The hot side is grey water. The cold side is fresh water. It extracts heat from the grey water. The fresh water is carried in tubing bundles in series immersed in grey water sumps in cylindrical plastic, mild steel, or stainless steel pipe. Both ends of the fresh water bundle assembly extend from the same upper end pipe closure, without a pressurized line wall penetration in the walls of the pipe. There is a non-electrically conductive barrier between the fresh water and grey water flow paths. The apparatus has a leak detection circuit and co-operable bypass valves. The tube bundle is wider at the top than at the bottom. The lower manifold has grey water passages between the centering ears. The entire assembly is enclosed in a unitary external housing with easily accessible connection fittings.
Patent CA-3029237-A1 (CA)
Title: Non-invasive, uniform and non-uniform rf methods and systems
Inventor: BOLL JAMES
IPC: A61B18/14
Filed: 2017-07-03
Abstract: Systems and methods utilizing RF energy to treat a patient's skin (e.g., dermis and hypodermis) or other target tissue including at a depth below a tissue surface (e.g., skin surface, mucosal surfaces of the vagina or esophagus) are provided herein. In various aspects, the methods and systems described herein can provide a RF-based treatment in which the deposition of RF energy can be selectively controlled to help ensure heating uniformity during one or more of body sculpting treatment (lipolysis), skin tightening treatment (laxity improvement), cellulite treatment, vaginal laxity or rejuvenation treatment, urinary incontinence treatment, fecal incontinence treatment, all by way of non-limiting examples. In various aspects, the systems can comprise one or more sources of RF energy (e.g., a RF generator), a treatment applicator comprising one or more electrode arrays configured to be disposed in contact with a tissue surface, and a return electrode (e.g., a neutral pad) to the tissue surface.
Patent CA-3030829-A1 (CA)
Title: Systemes de motorisation hybride pour operations de stimulation de puits
Inventor: COSKREY BILLY DON
IPC: F04D29/02
Filed: 2016-09-02
Abstract: Selon les modes de réalisation, la présente invention concerne un système de motorisation hybride qui utilise des multiples sources d'énergie mécanique pour entraîner une pompe. Le système de motorisation hybride peut comprendre : un premier moteur, pour générer une première énergie mécanique ; une pompe ; une chaîne cinématique, pour fournir une première énergie mécanique du premier moteur à la pompe ; et un deuxième moteur, à l'intérieur de la chaîne cinématique, pour générer et pour fournir une deuxième énergie mécanique à la pompe. Les multiples sources d'énergie mécanique peuvent fournir une flexibilité en ce qui concerne la conception du système et permettre d'utiliser des sources alternatives de combustible et d'énergie pour entraîner des systèmes de pompage. Ceci peut réduire la consommation totale de carburant diesel, nécessaire pour effectuer une opération de stimulation de puits ainsi que fournir des configurations permettant de s'affranchir des moteurs diesel dans le processus de pompage, et d'utiliser à leur place des sources d'énergie alternatives qui ne présentent typiquement pas de capacité de couple suffisante pour alimenter une pompe.
Patent CA-3030906-A1 (CA)
Inventor: CARLSON CRAIG L
IPC: H04W72/04
Filed: 2017-08-16
Abstract: A BLUETOOTH® enabled computing device is configured to use a "pseudo" device identifier to prevent undesired device interference during BLUETOOTH® pairing. The computing device includes a processor configured to a) retrieve a first BLUETOOTH® device identifier used for identifying the computing device, b) convert the first BLUETOOTH® device identifier into a second unique BLUETOOTH® device identifier specific to a connection between the first computing device and a second computing device, c) advertise availability of the computing device using the second BLUETOOTH® device identifier, wherein the second BLUETOOTH® device identifier is available for use in connection to the second computing device, d) receive a pairing request from a second computing device, and e) establish a BLUETOOTH® communications path between the computing device and the second computing device, wherein the BLUETOOTH® communications path is created based at least partially on the second BLUETOOTH® device identifier.
Patent CA-3031104-A1 (CA)
Inventor: RAIBLE MORITZ
IPC: B26B9/00
Filed: 2019-01-22
Abstract: Blade for a stripping and peeling tool for stripping and peeling a pre-insulated pipe, including a main body, wherein the main body is configured as an elongate thin plate, wherein the plate is configured so as to be convex and the apex of the convex curvature extends along the length of the plate, wherein a cutting edge is disposed on a longitudinal edge of the plate, or of the main body, respectively, said cutting edge serving for releasing an insulation layer from an internal pipe, and an insert blade, characterized in that the insert blade is configured as a separate part and the blade includes an axle, wherein the axle serves for mounting the insert blade in the main body and preferably protrudes through the insert blade, wherein the insert blade has a cutting edge and the insert blade is disposed in the main body in such a manner that the cutting edge of the insert blade runs parallel to the cutting edge on the main body.
Patent CA-3033023-A1 (CA)
Title: A retractable staircase
Inventor: BIANCHI ZEV
IPC: B60R3/02
Filed: 2016-08-10
Abstract: A retractable staircase comprising a first side stringer and a second substantially parallel side stringer connected to a plurality of steps. The first side stringer is fixedly attached to a wall and the second side stringer is pivotally movable about the first side stringer between an extended position, where the steps lie substantially horizontally between the stringers, and a retracted position where the steps lie substantially vertically between the stringers. The retractable staircase also includes a collapsible handrail and a gate that are interconnected with the side stringers and the pivoting steps so that when one of them is moved, the other two move substantially simultaneously.
Patent CA-3033139-A1 (CA)
Inventor: AUBRY XAVIER
IPC: A45B11/00
Filed: 2016-11-24
Abstract: The parasol (10) includes: a base (30) comprising a pole (32), a head (20) secured to one end of said pole (32) and comprising a canvas (22) capable of filtering at least part of the rays of the sun, and a structure (21) intended for supporting said canvas (22) and deformable between a first so-called "open configuration," wherein the canvas (22) is outstretched, and a second so-called "folded configuration," wherein the canvas (22) is folded. The support structure (21) comprises a hoop (210), referred to as a "peripheral hoop", which is closed in on itself and lies in a plane in the open configuration of the support structure (21). Said parasol is characterized in that the canvas (22) is attached inside the peripheral hoop (210) such that said canvas (22) is stretched out inside said peripheral hoop (210), in the open configuration of the support structure (21).
Patent CA-3033153-A1 (CA)
Title: Cle de commande d'un verrou a fiche cylindrique et verrou de validation de cette cle
Inventor: HOLDA JIRI
IPC: E05B19/00
Filed: 2017-08-21
Abstract: L'invention concerne une clé de commande d'un verrou à fiche cylindrique, le corps de sa tige (10) étant, au moins dans une partie de sa longueur, formé par un profilé creux partiellement fermé dont la surface arrondie extérieure (16) est façonnée pour faire tourner la clé dans la cavité du verrou, alors qu'au moins dans la partie d'extrémité (12) de la section latérale de la tige (10), une cavité ouverte est créée pour insérer un bras du levier de validation (5) du verrou. Au moins une partie de la tige (10) est réalisée en forme de U ou de V, alors que dans au moins une telle partie de la tige (10), le fond et/ou la paroi de l'arceau intérieur et extérieur de la tige (10) sont pourvus d'au moins une piste de codage (9) ouverte et/ou d'au moins un canal de codage (18) ayant une surface de codage façonnée. Le verrou de validation de la clé contient au moins une fiche cylindrique (1) qui peut tourner dans son logement (2). Dans le corps de fiche (1), une barre latérale suspendue (3) du verrou se trouve dans sa rainure longitudinale extérieure, poussée vers la surface intérieur du boîtier (2). La barre latérale (3) est conçue pour être insérée dans les leviers de validation (5) rotatifs qui sont disposés en une rangée dans l'axe longitudinal de la fiche (1) sur le pivot dans la fiche (1) et ils sont situés dans les fentes latérales (6) le long de la longueur de la fiche (1). Ces leviers de validation (5), dans le cas d'un codage incorrect de la clé (11), se trouvent dans un état fonctionnel bloqué dans une position qui empêche l'insertion de la barre latérale (3) dans la rainure (23) dans la fiche (1), et ainsi la rotation de la fiche (1) à l'intérieur du boîtier (2) du verrou, alors que dans l'état débloqué, dans le cas d'un codage correct de la clé (11), ils se trouvent dans la position fonctionnelle qui permet le déplacement de la barre latérale (3) dans la direction vers l'intérieur de la rainure (23) dans la fiche (1) et ainsi la rotation de la fiche (1) à l'intérieur du boîtier (2) du verrou. Les leviers de validation (5) font saillie au moins partiellement dans la cavité de la clé (11), ce qui leur permet d'établir un contact entre les leviers de validation (5) et des porteurs de code, lesquels sont les pistes (9) ou les canaux (18) de codage dans la clé (11).
Patent CA-3033580-A1 (CA)
Inventor: MILLAR GARY BRET
IPC: A01G31/02
Filed: 2018-05-21
Abstract: A fluid removal system for an assembly line grow pod is provided. The fluid removal system includes a track, a cart configured to move on the track, a fluid removal manifold provided over the track, and a controller. The cart includes one or more cells. The fluid removal manifold includes a body, and one or more nozzles attached to the body. The controller determines whether fluid in the cart needs to be removed, operates the fluid removal manifold to align the one or more nozzles with the one or more cells of the cart in response to determination that the fluid in the cart needs to be removed, and instructs the fluid removal manifold to remove fluid from one or more cells of the cart through the one or more nozzles.
Patent CA-3034501-A1 (CA)
Inventor: DOLMANSLEY TIMOTHY
IPC: F23R3/34
Filed: 2017-09-19
Abstract: A pilot burner assembly for a combustion chamber in a gas turbine engine is presented. The pilot burner assembly includes a pilot burner and a radial swirler. On a burner head face of the pilot burner, pilot fuel injection holes are present for providing pilot fuel. The swirler has swirler vanes arranged circumferentially and radially disposed around the burner head face with respect to a center of the burner head face. The swirler vanes have radially inner thin ends that define a burner region. Each pilot fuel injection hole is positioned such that a distance of the hole is equal to or less than 50 percent of a distance of an edge of the burner region, both distances measured from the center of the burner head face along a straight line from the center passing through the hole to the edge of the burner region.