baber/WOPTO huggingface dataset:
Patent EP-2723762-A1 (EP)
Title: Binding inhibitors of the beta.transducin repeat - containing protein
Inventor: BRADLEY MARK
IPC: A61K38/08
Filed: 2012-06-27
Abstract: The present invention relates to compounds which bind to Beta Trans-ducin repeat-containing protein (PTrCP), and modulate the activity of l3TrCP. In particular, the invention relates to compounds which demonstrate optimised binding to PTrCP. The invention also relates to pharmaceutical compositions comprising such compounds and the use of such compounds as medicaments, specifically for the treatment of disorders associated with aberrant protein degradation, such as cancer. The preferred binding inhibitors are peptides derived from the motive DSGXXS, e.g. DEGFWE, DDGFWD and Succinyl-EGFWE.
Patent EP-2877467-A1 (EP)
Inventor: ATKINSON STEPHEN JOHN
IPC: C07D471/04
Filed: 2012-07-26
Abstract: Compounds of formula (I) wherein; R 1  is hydrogen or C 1-6 alkyl; R 2  is hydrogen, C 1-6 alkyl, perhalomethylC 0-5 alkyl-O-, or C 1-6 alkoxy; R 3  is hydrogen, C 1-6 alkyl, or C 1-6 alkoxyC 1-6 alkyl; R 4  is hydrogen, C 1-6 alkyl, perhalomethylC 1-6 alkyl; or unsubstituted C 3-6 cycloalkylC 1-6 alkyl; A is C-R 5  or N; B is C-R 6  or N; D is C-R 7  or N; with the proviso that at least one of A, B, and D, is N; R 5  is hydrogen or C 1-6 alkyl; R 6  is hydrogen or C 1-6 alkyl; R 7  is hydrogen, C 1-6 alkyl, C 1-6 alkoxy, or hydroxy; R 8  is hydrogen or C 1-6 alkyl, with the proviso that one of R 4  and R 8  is hydrogen; R 9  is hydrogen or hydroxy; R 10  is hydrogen or C 1-6 alkyl; and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis.
Patent EP-2674415-A1 (EP)
Inventor: RASNETSOV LEV DAVIDOVICH
IPC: C07C237/06
Filed: 2012-02-06
Abstract: The invention relates to the pharmaceutical industry and to medicine, specifically to novel homo- and hetero-polyamino-acid derivatives of fullerene C 60  of general formula: C 60 (H) x {NH(CH 2 ) n COO-} x {NH 3   + (L)COOH)} x , where n = 2-5, x = 3, L = -(CH 2 ) m , where m = 1-5, or -CO(CH 2 ) k CH(NH 2 )-, where k = 1-2, characterized in that the compounds comprise covalently bonded amino-acid groups and polar ionic forms of the amino acids, and also to a method for producing said derivatives, and to the production of pharmaceutical compositions based on same. The method for producing homo- and hetero-polyamino-acid derivatives of fullerene is based on the reaction of a nucleophilic bond of amino acids to fullerene, forming covalently bonded amino-acid derivatives of fullerene, with the subsequent introduction of polar ionic forms of the amino acids. A pharmaceutical composition comprises, as active substance, homo- and hetero-polyamino-acid derivatives of fullerene of formula 
 
        C 60 (H) x {NH(CH 2 ) n COO-} x {NH 3   + (L)COOH)} x , where n = 2-5, x = 3, L = -(CH 2 ) m , where m = 1-5, or -CO(CH 2 ) k CH(NH 2 )-, where k = 1-2.
Patent EP-2873178-A1 (EP)
Inventor: HAMMARWALL DAVID
IPC: H04B17/00
Filed: 2012-07-12
Abstract: L'invention concerne un équipement utilisateur comprenant : un processeur ; et une mémoire d'instructions. La mémoire d'instructions assure le stockage des instructions qui, une fois exécutées, amènent l'équipement utilisateur à : recevoir au moins une commande d'un nœud réseau ; obtenir au moins une première mesure de l'information état de canal et une deuxième mesure de l'information état canal en réponse à ladite au moins une commande ; déterminer si une interférence correspondant à la deuxième mesure de l'information état canal apparaît pendant une phase de réception de données ; et décoder les signaux reçus, lorsqu'une interférence correspondant à la deuxième mesure de l'information état canal apparaît, sur la base de la deuxième mesure de l'information état canal.
Patent EP-2677487-A1 (EP)
Inventor: FUKUMA MIKIO
IPC: G06Q50/10
Filed: 2012-02-07
Abstract: An operator selecting device (10) includes an itinerary storage unit (13a) that stores therein areas that a user is scheduled to visit in association with each user identifying information that identifies the user. The operator selecting device (10) includes a used language storage unit (13b) that stores therein a language used in an area in association with each area. The operator selecting device (10) includes a handling language storage unit (14a) that stores therein a language an operator can handle in association with each operator. The operator selecting device (10) identifies, when an inquiry including user identifying information is received from a terminal (30), a language used in an area that the user stored in the itinerary storage unit (13a) in association with the user identifying information is scheduled to visit thereafter by referring to the used language storage unit (13b). The operator selecting device (10) selects an operator who can handle a language used in the current area of stay of a user and a language used in an area that the user is scheduled to visit thereafter.
Patent EP-2742046-A1 (EP)
Title: Composés de pyrazolo[3,4-c]pyridine et procédés d'utilisation
Inventor: DO STEVEN
IPC: A61P35/00
Filed: 2012-08-10
Abstract: La présente invention concerne des composés de pyrazolo[3,4-c]pyridine de formule I, comprenant des stéréoisomères, des isomères géométriques, des tautomères, et des sels pharmaceutiquement acceptables de ceux-ci, dans lesquels R 1  et R 2  sont tels que définis dans la description, qui sont utiles pour inhiber la kinase Pim, et pour traiter des troubles tels qu'un cancer médié par la kinase Pim. La présente invention concerne en outre des procédés d'utilisation des composés de formule I pour le diagnostic  in vitro ,  in situ , et  in vivo , la prévention ou le traitement de tels troubles dans des cellules de mammifère, ou des affections pathologiques associées.
Patent EP-2744673-A1 (EP)
Inventor: POWELL IAN
IPC: B60D1/155
Filed: 2012-08-17
Abstract: L'invention concerne un ensemble d'attelage de remorquage (22) destiné à être fixé sur un contenant mobile (18), l'ensemble d'attelage de remorquage comprenant une première partie (24) pouvant être raccordée au contenant mobile et une seconde partie (26) pouvant être fixée sur un contenant adjacent ou un véhicule de remorquage, la seconde partie étant mobile de façon coulissante par rapport à la première partie entre une première configuration rétractée et une seconde configuration déployée.
Patent EP-2720947-A1 (EP)
Title: Organe d'accrochage destiné à faciliter l'atterrissage d'un aéronef sur une surface d'accès
Inventor: BESENZONI GIOVVANNI
IPC: B64F1/12
Filed: 2012-06-15
Abstract: L'invention porte sur un organe d'accrochage (1) destiné à faciliter l'atterrissage d'un aéronef sur une surface d'accès (G). L'organe d'accrochage selon l'invention comprend un groupe de soutien (2) qui fait saillie depuis les plaquettes de soutien (P) de l'aéronef, plaquettes de soutien auxquelles est fermement couplé un ensemble de préhension (3) relié au groupe de soutien (2) et comprenant une pluralité de corps fonctionnels projetés vers le bas (4) et, en particulier, des moyens d'actionnement (5). Lesdits moyens d'actionnement (5) sont fonctionnellement reliés aux corps fonctionnels (4) de l'ensemble de préhension (3) de façon qu'ils les placent dans une position de repos ou les en retirent, en fonction de quoi les corps fonctionnels (4) pendent librement en direction d'une position de fonctionnement ou depuis une position de fonctionnement, et en fonction de quoi lesdits corps fonctionnels (4) entrent en contact avec la surface d'accès (G) de façon qu'ils pénètrent au moins en partie dans cette dernière et sont liés fermement mais de manière amovible à ladite surface (G), améliorant les conditions de sécurité au cours de l'atterrissage de l'aéronef sur ladite surface d'accès, qui peut être, par exemple, une plateforme d'atterrissage à correction automatique d'assiette (G) disposée sur une embarcation.
Patent EP-2769090-A1 (EP)
Inventor: ZIEGLER SEBASTIAN
IPC: F03D11/00
Filed: 2012-09-14
Abstract: Ein Lager (200) zum Einstellen eines Anstellwinkels eines Rotorblatts (220) einer Windkraftanlage umfasst einen ersten Lagerring (230) und einem zweiten Lagerring (240), wobei der erste (230) und der zweite Lagerring (240) zueinander drehbar sind, wobei der erste Lagerring (230) als Translator eines Linearmotors (100) eine Mehrzahl (350) von entlang eines Teils seines Umfangs benachbart zueinander angeordneten Magnetfeldquellen (110) umfasst, wobei die Magnetfeldquellen (110) so ausgebildet sind, dass jeweils zwei benachbart zueinander angeordnete Magnetfeldquellen (110) ein Magnetfeld mit alternierender Polarität erzeugen, wobei die Mehrzahl (350) von Magnetfeldquellen (110) in einem vorbestimmten Winkelbereich (360) bezogen auf einen Mittelpunkt (310) des ersten Lagerrings (230) entlang seines Umfangs angeordnet ist, an den sich unmittelbar ein weiterer vorbestimmter Winkelbereich (370) anschließt, in dem keine Magnetfeldquellen angeordnet sind, und wobei der zweite Lagerring (240) als Stator des Linearmotors (100) eine Gruppe (190) von wenigstens zwei entlang eines Teils seines Umfangs benachbart zueinander angeordneten Spulen (170) umfasst.
Patent EP-2747817-A1 (EP)
Inventor: GARDE SMITA
IPC: A61M16/00
Filed: 2012-08-14
Abstract: A method and apparatus provide closed-loop control of the operation of a ventilator device based on physiological parameters received from and/or through a patient monitor device, which is a separate and discrete device from the ventilator device.
Patent EP-2788224-A1 (EP)
Inventor: FOLTIN JOHANNES
IPC: G06V10/56
Filed: 2012-10-09
Abstract: The invention relates to a method for identifying a braking situation of a vehicle (102, 104) situated on a traffic route, said method comprising a step of determining a red component of at least one image region of an image depicting at least one section of the traffic route (420), and a step of determining the braking situation based on the red component.
Patent EP-2765821-A1 (EP)
Inventor: WANG CHONG
IPC: H04W76/02
Filed: 2012-02-01
Abstract: Disclosed are a multi-mode terminal service switchover method and device. The method comprises: a multi-mode terminal performing data transmission for a Packet Switch (PS) service requested by a user through an activated packet data protocol PDP link; when detecting an available network in a current network environment, the multi-mode terminal activating a PDP link corresponding to the detected available network; and the multi-mode terminal performing data transmission for the PS service through one or more PDP links in the activated PDP links. Through the present invention, the problem that a multi-mode terminal cannot implement high speed data transmission for a PS service by using network resources of multiple communication networks is solved, and the effect of multi-network binding high speed data transmission for a PS service is achieved.
Patent EP-2785791-A1 (EP)
Title: Dual cure system
Inventor: KOERS FREDERIK WILLEM KAREL
IPC: C08L67/06
Filed: 2012-11-29
Abstract: Multi-pack curable composition comprising: a first pack comprising a blend of (i) an epoxy resin, (ii) an unsaturated polyester or vinyl ester resin, and optionally (iii) a peroxyester, a second pack comprising an amine curing agent for the epoxy resin and at least one transition metal compound selected from iron, copper, and manganese compounds, and at least when the first pack does not contain a peroxyester, a third pack comprising a peroxide.
Patent EP-2715887-A1 (EP)
Title: Connecteurs optiques robustes à fibre laser d'énergie élevée passivement refroidie et procédés d'utilisation
Inventor: RINZLER CHARLES C
IPC: H01S3/30
Filed: 2012-06-01
Abstract: L'invention concerne des connecteurs à laser d'énergie élevée et des coupleurs et des procédés qui sont capables de fournir une énergie laser élevée sans la nécessité de refroidissement actif d'emplacements à distance, durs et difficiles d'accès et sous des conditions difficiles et dures, et de diriger et d'atténuer les effets négatifs de rétroréflexions.
Patent EP-2787980-A1 (EP)
Inventor: HERRY CATHERINE
IPC: A61K9/20
Filed: 2012-12-06
Abstract: L' invention concerne une composition pharmaceutique orale sous forme de comprimé à libération prolongée comprenant un principe actif susceptible d'être détourné, laquelle composition permet de lutter contre le détournement par voie injectable.
Patent EP-2777166-A1 (EP)
Inventor: YU QISHAN
IPC: H04B1/00
Filed: 2012-11-21
Abstract: A wireless electronic device may be used to communicate using multiple wireless standards in adjacent frequency bands. The wireless standards may include Wi-Fi® and cellular standards such as Long Term Evolution (LTE). The wireless electronic device may be provided with wireless communications circuitry that handles Wi-Fi® and cellular signals in adjacent frequency bands such as the Wi-Fi® 2.4 GHz frequency band and LTE bands 38 and 40. The wireless communications circuitry may include a triplexer interposed between transceiver circuitry and an antenna. The triplexer may be used to handle radio-frequency signals in adjacent frequency bands by separating the radio-frequency signals into signals associated with each frequency band. The triplexer may include filters that each pass signals in a respective one of the frequency bands between the transceiver circuitry and the antenna.
Patent EP-2877178-A1 (EP)
Inventor: WYNNE NEIL
IPC: A61P25/04
Filed: 2012-10-08
Abstract: The invention provides a method of assembling a device and a kit suitable for administration to multiple patients comprising a multi-dose pharmaceutical composition of nasal analgesic in the form of a nasal spray. The present invention also provides a method for reducing the respiratory depressant effect associated with diamorphine administration, the method comprise a single dose pharmaceutical composition comprising lyophilized diamorphine and a diluent for reconstitution, wherein the dose of diamorphine is 0.1mg/kg body weight.
Patent EP-2719936-A1 (EP)
Inventor: NAKAJIMA TETSUYA
IPC: A61M25/09
Filed: 2012-05-07
Abstract: Provided are a resin tube (1) for a guide wire, a method for manufacturing a resin tube for a guide wire, and a guide wire, configured such that the resin tube (1) makes point contact in the axial direction with an object of contact at working site, thereby reducing frictional resistance and yielding excellent sliding properties, while also being prevented from kinking and collapsing, and having excellent buckling resistance. The resin tube (1) for a guide wire is characterized in that the outer shape of a cross-section (S10) perpendicular to the axial direction is polygonal, elliptic, or irregular, that the resin tube (1) is twisted in a helical shape about a deep inner-core hole (16) as the axis oftwisting (O1), the deep inner-core hole (16) extending in the axial direction and allowing a core wire to be inserted therein, and that the resin tube (1) is provided with a trunk section (10) having an undulation on the outer surface (12) caused by the twisted eccentric wall thickness.
Patent EP-2724235-A1 (EP)
Title: Débogage interopératif en temps de fonctionnement à n voies
Inventor: DAVIS JACKSON M
IPC: G06F11/36
Filed: 2012-06-06
Abstract: L'invention concerne le débogage simultané d'un code fonctionnant dans de multiples types d'environnement de temps de fonctionnement qui peut être effectué par un environnement de débogage interopératif à N voies. Le code fonctionnant dans un temps de fonctionnement particulier peut être débogué en même temps qu'un code tournant dans d'autres temps de fonctionnement au cours d'un seul processus. Un support de débogage hors processus est fourni pour la commande d'inspection et d'exécution. Un débogueur compatible ou un protocole de communication en temps de fonctionnement est utilisé. Les transitions d'un temps de fonctionnement vers un autre temps de fonctionnement peuvent être détectées. Les exceptions envoyées dans un temps de fonctionnement peuvent être rattrapées par un autre temps de fonctionnement. Des opérations de modifications d'instructions peuvent se produire dans de multiples temps de fonctionnement. Une pile d'appels comprenant des trames de multiples temps de fonctionnement peut être parcourue.
Patent EP-2728662-A1 (EP)
Inventor: OKADA KENICHI
IPC: H01M2/08
Filed: 2012-06-27
Abstract: The present invention is a dye-sensitized solar cell including a first electrode; a second electrode that faces the first electrode; an electrolyte that is disposed between the first electrode and the second electrode; and an annular encapsulation unit that surrounds the electrolyte together with the first electrode and the second electrode, and connects the first electrode and the second electrode, wherein the sealing portion has a resin sealing section formed of a resin, at least one interface of a first interface between the first electrode and the sealing portion, and a second interface between the second electrode and the sealing portion, constitutes a wide width section having the broadest sealing width among the sealing widths of the sealing portion, and the sealing portion has a narrow width section having a narrower sealing width than the wide width section.
Patent EP-2800902-A1 (EP)
Inventor: KUNY MARKUS ERNST
IPC: F04B39/06
Filed: 2012-12-07
Abstract: The invention relates to a pump. The pump has a pump housing comprising a first and second housing part (1, 2). The first housing part (1) has a first fluid port (10) and a first face side (8). The second housing part (2) has a second fluid port (27) and a second face side (9). The second housing part is axially connectable with the first housing part (1). Further, the pump has a pump motor in the first housing part (1) and a fluid mover in the second housing part (2). The fluid mover is drivable by the pump motor. Further, the pump has a housing part connecting device (3) for axially connecting the first housing part (1) and the second housing part (2) with each other. The housing part connecting device (3) is adjustable between a connecting and a release position. In the connecting position, the first housing part (1) and the second housing part (2) are fixed in an axial and rotary manner with each other. In the release position, the first housing part (1) and the second housing part (2) are pivotable relative to each other and are fixed in an axial manner with each other.
Patent EP-2729757-A1 (EP)
Inventor: PETTERSSON THOMAS
IPC: F42B10/64
Filed: 2012-06-26
Abstract: The invention relates to a rotationally stabilized projectile (1) for launching from a barrel, which projectile (1 ) comprises a front projectile part (22), a rear projectile part (20) comprising a rotating band (4), and an intermediate projectile part (21) comprising a freely rotatable middle section (2) arranged with guide wings (3) for improving the gliding capability and guidance capability during the gliding phase and end phase of the projectile. The guide wings (3) are arranged extensibly on the freely rotatable middle section (2), and the intermediate projectile part (21) also comprises a regulator device (14) for regulating the rotation of the middle section (2). The invention also relates to a method for guiding a rotationally stabilized projectile.
Patent EP-2791171-A1 (EP)
Title: Expression d'anticorps iga sécrétoires chez la lentille d'eau
Inventor: ARIAANS GERARDUS JOSEPH ANDREAS
IPC: A61P1/00
Filed: 2012-12-14
Abstract: Selon la présente invention, des anticorps IgA sécrétoires peuvent être fabriqués par expression dans une lentille d'eau transformée de façon stable.
Patent EP-2741955-A1 (EP)
Title: Dépôt offshore flottant stable
Inventor: VANDENWORM NICOLAAS
IPC: B63G11/00
Filed: 2012-02-09
Abstract: L'invention concerne un dépôt offshore doté d'une coque verticalement symétrique, d'une paroi supérieure rétrécissant en cône et d'une paroi inférieure s'élargissant en cône, qui créent un amortissement significatif du pilonnage en réponse à l'action d'une forte houle. Du lest est ajouté aux parties inférieure et supérieure extrêmes de la coque pour abaisser le centre de gravité au-dessous du centre de flottabilité. Le dépôt offshore comprend un tunnel formé dans ou à travers la coque au niveau de la ligne de flottaison, qui constitue une zone abritée à l'intérieur de la coque pour le lancement / l'accostage sûrs et aisés d'embarcations et l'embarquement / le débarquement de personnel. Lorsque les portes étanches du tunnel sont toutes fermées, le tunnel peut être asséché pour créer un environnement de cale sèche à l'intérieur de la coque. Le dépôt offshore comprend des logements avec couchettes et restauration, des installations médicales, des ateliers, des salles des machines, un héliport, etc.
Patent EP-2747811-A1 (EP)
Inventor: EATON ALEXANDER M
IPC: A61F9/00
Filed: 2012-08-23
Abstract: Devices, systems, and methods for performing injections with lowered likelihood of infection include needles and other injection means with protective sleeves or sheaths. The protective sleeve can protect the needle before, during, or before and during an injection. The force needed to administer an injection or penetrate an insertion site using an injection device or system with a protective sleeve can be about the same to up to 50% more than the force needed for a system or device without a protective sleeve. The force needed to collapse the protective sleeve can be less than 100 gram-force. The material, the thickness, or both the material and the thickness of the protective sleeve may differ when comparing the portion of the sleeve near the needle tip and the portion near the base of the needle.
Patent EP-2751764-A1 (EP)
Inventor: RAZA MIRZA MUHAMMAD
IPC: G06Q30/02
Filed: 2012-08-06
Abstract: One or more techniques and/or systems are disclosed for providing a customized advertisement for a user. A request can be received from an advertising service, where the request comprises a user topic, such as a topic comprised in an advertisement intended to be customized for the user. One or more user aspects are identified for the user topic, and respective impact factors are determined for at least some of the one or more user aspects. The user aspects for the user topic can be ranked according to their corresponding impact factors, and the ranking can be returned to the advertising service in response to the request. The advertising service may use at least some of the ranking to customize the advertisement to be shown to the user (e.g., so that higher ranked aspects are emphasized more heavily in the advertisement than lower ranked aspects).
Patent EP-2752282-A1 (EP)
Inventor: MIYASHITA TAKAYUKI
IPC: B29C33/38
Filed: 2012-08-30
Abstract: Provided is a technology for suppressing, in a mold having a heat-insulating layer formed therein, a problem of chipping of the heat-insulating layer and the like even when a penetrating member is inserted through a through-hole provided in the mold. The mold is provided with a mold body having a convex part on an inner wall surface of the mold body, a heat-insulating layer arranged on the inner wall surface, and a through-hole which penetrates the convex part in a thickness direction of the mold body and through which the penetrating member can be inserted. An outer periphery of the through-hole is inside an outer periphery of a top surface of the convex part. A spacing between the outer periphery of the through-hole on the top surface of the convex part and the outer periphery of the top surface of the convex part is preferably 0.5 mm or less.