baber/WOPTO huggingface dataset:
Patent DO-P2023000208-A (DO)
Title: 3,4-dihidro-2,7-naftiridin-1,6(2h,7h)-dionas como inhibidores de mek
Inventor: LI REN
IPC: A61K31/4375
Filed: 2023-09-28
Abstract: La invención se refiere a un compuesto de la Fórmula I o una sal aceptable desde el punto de vista farmacéutico de este, en donde R1, R2, R3 y R4 son como se definen en la presente. La invención se refiere además a composiciones farmacéuticas que comprenden dichos compuestos y sales, y a procedimientos para la fabricación de medicamentos y usos de dichos compuesto, sales y composiciones para el tratamiento del crecimiento celular anormal, que incluye cáncer, en un sujeto que lo necesita. La invención se refiere además a formas sólidas de 8-((2-fluoro-4-(metiltio)fenil)amino)-2-(2-hidroxietoxi)-7-metil-3,4-dihidro-2,7-naftiridin-1,6(2H,7H)-diona.
Patent EC-SP11011483-A (EC)
Title: Piperidinas sustituidas
Inventor: JESKE MARIO
IPC: A61K31/541
Filed: 2011-11-25
Abstract: La invención se refiere a nuevas piperidinas sustituidas, a procedimientos para su preparación, al uso de las mismas para el tratamiento y/o profilaxis de enfermedades y al uso de las mismas para la producción de medicamentos para el tratamiento y/o profilaxis de enfermedades, especialmente de enfermedades cardiovasculares y enfermedades tumorales.
Patent EC-SP13013029-A (EC)
Title: Surfactantes para la recuperación mejorada de petróleo
Inventor: RAVIKIRAN RAMAKRISHNA
IPC: E21B43/22
Filed: 2013-11-18
Abstract: Las composiciones surfactantes útiles para la recuperación de petróleo comprenden de 10 a 80 % en peso de sulfato de alcohol C12-C20 propoxilado, de 10 a 80 % en peso de un sulfonato de olefina interna C12-C20 y de 0,1 a 10 % en peso de un sulfato de alcohol C4-C12 etoxilado. Una proporción menor del sulfato de alcohol etoxilado reduce o elimina la necesidad de recurrir a cosolventes costosos para alcanzar buen desempeño en procesos de recuperación mejorada de petróleo. Se pueden alcanzar bajas tensiones interfaciales y una microemulsión de baja viscosidad cuando el sulfato de alcohol etoxilado acompaña al sulfato de alcohol propoxilado y al sulfonato de olefina interna. También se revelan concentrados acuosos que comprenden agua y las composiciones surfactantes arriba descritas. La dilución de la composición del surfactante o concentrado acuoso con agua o salmuera hasta el nivel deseado de activos aniónicos proporciona una composición inyectable útil para aplicaciones de EOR. También se revelan microemulsiones estables, de baja viscosidad de petróleo en agua que comprenden petróleo crudo, agua y las composiciones surfactantes.
Patent EG-23575-A (EG)
Title: A tightening system for secure connection of at least two elements with one another
Inventor: KOPPENHOEFER PETER
IPC: F16B5/02
Filed: 2004-12-25
Granted: 2006-07-26
Abstract: A tightening system for secure connection of at least two elements (1, 2) with one another has a connecting member (3, 3') extending in openings provided in the elements and having two opposite ends (4, 5) with at least one of the ends (4) adapted to extend outwardly beyond at least one of the elements. A spacer member (6) is arranged rotatably between the elements (1, 2), holding means (7) are arranged at the other end of the connecting member (3, 3'), and a tightening member (11) is arranged on the at least one end of the connecting member. The spacer member (6) is freely rotatable on the connecting member (3, 3') to prevent cutting of the connecting member. <IMAGE>
Patent EG-25258-A (EG)
Title: Anchoring devices for rail fastening clips.
Inventor: COX STEPHEN JOHN
IPC: E01B9/30
Filed: 2008-08-19
Granted: 2011-11-29
Abstract: A sealing plate for use with a rail clip anchoring device having a head and a stem which extends from the head into a concrete sleeper when the anchoring device is in use, is adapted for extending over the underside of the head when the stem of the device is being set in a concrete sleeper, thereby to prevent ingress of concrete into the head of the device, and for being retained on the surface of the sleeper thereafter. A major face of the plate, which is uppermost when the sleeper is in use, is provided with at least one clip seat portion for receiving part of a rail clip. In a method of manufacturing a concrete sleeper with at least one embedded rail clip anchoring device, the floor of a mold, from which the sleeper is to be formed, is provided with an aperture through which the head of an anchoring device is inserted and before concrete is introduced into the mold the aperture is sealed off around its edges and around the underside of the head of the anchoring device by placing a sealing plate over the aperture on the floor of the mold, the plate overlapping and sealing around the edges of the aperture other than where the anchoring device is located and having a mating interface with the anchoring device such that a seal is formed therewith.
Patent GB-189701411-A (GB)
Title: Improvements in Targets.
Inventor: PARNALL WILLIAM
Filed: 1897-01-19
Granted: 1898-03-12
Abstract: 1411. Parnall, W., and Burns, T. B. Jan. 19. Targets.-Figs. 1 and 3 show, respectively, a front and side elevation of a target and its signalling dummy. The target is of canvas stretched over a suitable frame and is carried by a spindle J mounted in bearings G, H supported on a rectangular framework and a pillar. It is partially balanced by a weight on an arm K<2> and is secured in the raised and lowered positions by spring catches 0, P respectively. These catches are released by means of a lever Q connected to them by cords or chains. The dummy M is carried by a stud projecting from the rear of the framework and has secured to it a pinion N in gear with another, L, on the spindle J so that the dummy rises as the target falls and vice versÔ. A bar M<2> projecting from the dummy carries a balance weight.
Patent GB-189706877-A (GB)
Title: Improvements in Hats and other Articles of Wearing Apparel.
Filed: 1897-03-16
Granted: 1898-02-05
Abstract: 6877. Cooper, Box, & Co. and Wildman, G. March 16. Appliances for securing to head; linings.-Relates to the method of securing hats to the head described in Specification No. 8987, A.D. 1895, in which a folded strip a of fabric is attached to the inside of the hat, and has along its projecting edge an elastic cord f the ends of which are tied together so as to put the cord in tension, and thereby cause the appliance to press against the wearer's head. This invention consists in placing outside the strip a a strip d of soft fabric sewn at its lower edge to the hat c, which may be of straw, and at its upper edge to a loose stiffer lining d<1> of celluloid or the like. The holes d<2> in the strip serve for ventilating purposes.
Patent GB-189707721-A (GB)
Title: Improvements in and connected with Pneumatic Tyres.
Inventor: WARRY JAMES JOSEPH
Filed: 1897-03-25
Granted: 1898-03-19
Abstract: 7721. Warry, J. J. March 25. Tyres, pneumatic.-Relates to air tubes and chambers, and means for attaching to the rim. To form the joint in single-tube tyres, one edge, thickened at i, fits into a continuous pocket k formed on the other. In one modification, the edge i may be formed as au inflatable tube, and, in another, the pocket k is situated in one of the tubular edges f of the rim and receives the inflatable tube formed on the other edge. This last arrangement also serves to attach the tyre to the rim, such attachment being otherwise effected by inflated tubes b as described in Specifications No. 19,909, A.D. 1895, and No. 10,127, A.D. 1897, or by other suitable means.
Patent GB-189713794-A (GB)
Title: An Improvement in Cooking Stoves.
Inventor: ASHLEY HOWARD MATRAVERS
Filed: 1897-06-04
Granted: 1897-07-17
Abstract: 13,794. Ashley, H. M. June 4. Cooking-ranges; grates and fuel-holders.-The bottom grate is curved, as shown in Fig. 1, and is pivoted at B. A rod D, pivoted at C, is employed to raise and lower it, and engages in one of the recesses in the racks E, F according to the required capacity of the grate.
Patent GB-189716357-A (GB)
Title: Improvement in Envelopes.
Inventor: SACKETT CHARLES EDGARD
Filed: 1897-07-10
Granted: 1897-08-14
Abstract: 16,357. Sackett, C. E. July 10. Envelopes.- Relates specially to means for sealing envelopes without the use of adhesive matter. The sealing-flap is bent over at the end to form a barb as shown in Figs. 8 and 9, which may if necessary be strengthened by a metal strip. Fig. 1 shows a suitable form of a blank. The bottom flap 8 is gummed to the side flaps 6, 7. The sealing-flaps 11, 12 are passed through the slots 9, 10, and the barbed ends catch over the bar portions 20, 21 of the side flaps. A modified form of blank suitable for cheap envelopes is described.
Patent GB-189716877-A (GB)
Title: Improvements in Railroad Switches.
Inventor: RICHEY CHAREN VANIVER
Filed: 1897-07-16
Granted: 1897-08-28
Abstract: 16,877. Richey, C. V., and Bailey, L. C. July 16. Points and switches, railway, operated from engines or vehicles. The tongues 3 are connected by a bar 4 seated on antifriction balls. They are operated from the engine by arms of various lengths thereon so as to strike the triggers 8, 10, or 22 which are connected to the points by rods 11, 20, and 25 and bell-cranks 9 and 24, as shown. One form of arm 17 on the vehicle shown in Fig. 5 is lifted by the cord 18 so as to lie in its operative position in the bracket 16.
Patent GB-189725138-A (GB)
Title: Improvements in and relating to Can Openers.
Inventor: BRADY JOHN
Filed: 1897-10-29
Granted: 1897-12-11
Abstract: 25,138. Brady, J. Oct. 29. Cans, opening.- A can-opening appliance consists of a bar B, with a cutting-wheel b, rotated round a centre formed by an ice pick C'.
Patent GB-189726020-A (GB)
Title: Improvements in the Construction of Sounding Boards.
Inventor: HADDAN REGINALD
Filed: 1897-11-09
Granted: 1898-04-16
Abstract: 26,020. Haddan, R., [Schmidtlein, C.]. Nov. 9. Drawings to Specification. Sound-magnifying appliances.-The invention consists in modifications of the soundboard described in Specification No. 23,711, A.D. 1897. The soundboards may be of uniform thickness, and cut away round the edge, as previously described, at one or both sides. When made of a thickness diminishing towards the edges, they may be cut away at either side.
Patent GB-189802312-A (GB)
Title: Improvements in Automatic Gas Igniting Devices for Incandescence and other Gas Lamps.
Filed: 1898-01-28
Granted: 1899-01-07
Abstract: 2312. J³rgens, J. F. C., and Automatic Universal Gas-Lighter. Jan. 28. Lighting gas.-Relates to automatic igniters of the platinumblack type for use with the pilot jets of incandescent and othel burners, the objects being to im prove the igniting action, minimize the risk of damage, and simplify the construction in such a manner that the device may be manipulated by an unskilled person. The porous material 1 containing the platinum black is secured in a refractory block or cylinder 3 by cement and by the platinum wires 2, which pass through the material 1 and are connected to the holder 5. The refractory material 3 protects the igniter proper from damage by the spring clips 4 of the holder, which slips over the upper end of the pilot tube. In a modification, the block 3 with the attached igniter is horizontally mounted in spring clips arranged slightly to one side of the holder 5.
Patent GB-189804088-A (GB)
Title: Improvements in Machines or Apparatus for Coating with Varnish, Gum, Size, Paste, or the like Adhesive Substance, Paper, Cardboard, or other Flexible Material.
Inventor: SEGGIE ALEXANDER HERVEY
Filed: 1898-02-18
Granted: 1899-01-28
Abstract: 4088. Seggie, A. H. Feb. 18. Coating surfaces with liquids and plastic materials; varnishing.-Relates to apparatus for coating paper or other flexible material with varnish, gum, size, paste, &c. The paper &c. is taken from the feed-table f by one or more sets of cam-actuated grippers G, G<1>, mounted on the revolving cylinder C, and is coated while on this cylinder by the rubber-coated roller K, which is supplied with the liquid from the trough B by the feed-roller L. The cylinder is covered with a packing-material having an outer waterproof covering. The coated sheets are taken from the cylinder C by the cam-actuated grippers Y on the endless chains Z, and are delivered on to the endless conveyer d, where they may be subjected to the drying action of heat, or air currents, &c. By means of a suitable change gearing, the conveyer can be driven at varying rates of speed, dependent on the size of the sheets, to obtain the maximum drying effect. Instead of employing the chains Z and conveyer, the sheets may be taken direct from the cylinder C, but, in either case, they are preferably placed to harden on trays or racks mounted on a trolley bottom. The trough B is automatically supplied with the liquid from the closed reservoir W. When the level of the liquid in the trough falls below the end of the supply pipe, a bubble of air enters the reservoir, and permits a further flow of liquid into the trough, the feed being thus independent of the rate at which the liquid is used. The trough can be interchanged for others, as required for different liquids. The rollers K, L are mounted on movable brackets H, the roller K being held against the cylinder C by springs O. In an alternative arrangement the roller L is mounted in eccentric bushes, and the roller K in bushes which slide in horizontal guides. When it is necessary to stop the coating operation, the roller K is moved away from the cylinder by operating the treadle V &c. Fig. 4 shows the striking-gear for the driving-belt, the belt fork h being mounted on the arm g on the boss x, which contains the bearing for the pulley shaft F. The fork is operated by hand or treadle, and, by adjusting the arm g, can be arranged to take the belt at any angle.
Patent GB-189804352-A (GB)
Title: An Improved Process and Apparatus for the Production and Purification of Acetylene Gas.
Inventor: WALKER HENRY
Filed: 1898-02-22
Granted: 1898-08-20
Abstract: 4352. Walker, H. Feb. 22. Acetylene.-Acetylene and carbonic-acid gases are produced simultaneously and purified as follows :-Within a lead-lined chamber a is placed a bucket b containing calcium carbide, chalk, or the like, and a dry acid such as oxalic acid. The bucket is provided with a stirring- device which is connected by a clutch e with a spindle g rotated by hand or power. Water is admitted by the pipe i, and the mixed gases produced are delivered by a pipe j into water in the lower part of a vessel k. The gases pass next by perforated tubes q, closed at the top, into a mass of crystals r of sulphate of iron, with which may be mixed copper turnings. From the vessel k the gases pass by a pipe u to the bottom of a vessel v containing water, and from this vessel they pass to a gasometer. The pipes i, j, i<1>, u, i<2>, and x are fitted with non-return valves.
Patent GB-189805675-A (GB)
Title: Improvements in Bottles to Prevent the Fraudulent Refilling thereof.
Inventor: GERLACH EMIL
Filed: 1898-03-08
Granted: 1898-06-18
Abstract: 5675. Gerlach, E. March 8. Stoppers; refilling, preventing.-Relates to stoppering bottles containing medicines, beverages, &c. so that they cannot be refilled after having been once emptied. The neck of the bottle is tapered at A', Fig. 1, to receive the valve casing B, which is secured to the neck by the washer 10 set in a groove in the casing. The casing B is made in two hollow conical parts 1, 2, Fig. 2, which are fitted together at 6 and secured by cement. The lower part 2 is formed with a seat 9 for the hollow float valve D, which is held on its seat by the ball C. The upper part 1 is formed with ports 3 for the outward passage of the contents, and with projections 5 arranged so as to prevent tampering with the valves. The valves D, C permit the liquid to be poured out but prevent refilling. The valves and casing &c. are made of glass, porcelain, or other suitable material, which will not inj uriously affect the contents of the bottle.
Patent GB-189806723-A (GB)
Title: Improvements in and connected with Puzzles.
Inventor: SVANSTROEM OLOF
Filed: 1898-03-19
Granted: 1899-03-11
Abstract: 6723. Svanstr÷m, O. March 19. Puzzles.-A framework carries two sets of projecting pins t<2>, s, upon which are placed balls r, coloured or otherwise identified. The object is to arrange the balls upon the pins according to a pre-arranged combination. To effect this, the balls are moved along from the pins on one set to the opposite pins on the neighbouring set. To move a ball to a pin above or below, the left-hand set of pins is displaced by suitable mechanism vertically, so that a ball comes opposite the pin upon which it is to be placed.
Patent GB-189812506-A (GB)
Title: Improvements in or relating to Tricycles or other Vehicles.
Inventor: BAINES WILLIAM
Filed: 1898-06-03
Granted: 1899-09-02
Abstract: 12,506. Baines, W. June 3. Motor road vehicles.-Relates to driving-gear for motor-driven vehicles, particularly for tricycles. The crank shaft of the motor A is geared, through a sprocket-wheel C and a chain with a sprocketwheel B on a hollow sleeve a on the crank axle of the tricycle. To vary the speed, unequal sprocketwheels E and F are provided on the crank axle, and gear respectively with sprocket-wheels H, J on the driven axle G, either of which can be engaged with this axle by a suitable clutch, or the clutch may be on the crank axle. The form of clutch shown in the Figure consists of frictiona cones or discs h, h<1> or j, j<1>. The crank axle carries the usual cranks D and pedals for use without, or to start, the motor, and preferably held stationary in the usual manner when the motor is driving.
Patent GB-189815542-A (GB)
Title: Improvements in or relating to the Protection of Water, Sewage, and other Pipes and Traps from Frost.
Inventor: ARCHIBALD JOHN
Filed: 1898-07-15
Granted: 1898-08-20
Abstract: 15,542. Archibald, J. July 15. Water supply.-Fig. 1 shows a method of protecting an indoor pipe A by a thin metal casing B packed with ground cork, sawdust, flock, or like material C. For outdoor or underground use where a metal casing would be subject to corrosion, a wooden casing D is used as shown in Fig. 2.
Patent GB-189816638-A (GB)
Title: Improvements in and connected with Steam Superheaters.
Inventor: HENKEL GUSTAV
Filed: 1898-07-30
Granted: 1899-07-08
Abstract: 16,638. Henkel, G. July 30. Steam - generator furnaces.-A wrought-iron spiral or serpentine tube, through which steam to be superheated is passed, is cast in a ring a of cast iron or steel embedded in a ring of refractory material forming the lining of the firebox of a steam boiler ; or the tube may be replaced by channels cast or formed in the ring Fig. 1 shows a continuous spiral tube. The firegrate is vertically adjustable in the ring, to vary the heating effect, by the links and levers shown. When a serpentine tube is used the ring a is not continuous, but has an open portion opposite the firedoor.
Patent GB-189819644-A (GB)
Title: A New System of Electric Propulsion.
Inventor: WHEATLEY WILLIAM HUMPHREY
Filed: 1898-09-15
Granted: 1899-07-15
Abstract: 19,644. Wheatley, W. H., [Rosenfeld, L., Zelenay, C., and Dulait, J.]. Sept. 15. Electric railways and tramways. Relates to a system of electric propulsion by means of alternating currents, applicable to railways, t r a m - ways, &c. In principle, the arrangement consists of an alternating-current induction motor, of which the inducing and induced elements are each extended into a straight line so that, instead of a rotary field, a rectilinearly-moving field is developed. Fig. 1 shows the application of the system to the propulsion of a tramway vehicle. The inducing-element consists of an extended iron body laid between the rails and provided with numerous transverse holes or notches, through which the alternating-current conductors I are wound. The induced element is composed of a number of iron blocks, similarly wound with conductors I, and suspended from the car by ropes C or similar means. Motion is transmitted from the suspended blocks to the car by rollers G, engaging with pivoted forks F, which are connected together at their upper ends by a rod T. The starting and stopping of the vehicle may be effected, either by connecting the induced coils together through the rheostat shown in Fig. 1<a>, or by raising and lowering the induced element by means of the lever arrangement shown in Fig. 1<b>.
Patent GB-189822718-A (GB)
Title: Improvements in Hydrocarbon Motors.
Inventor: HEADECH ERNEST THOMAS
Filed: 1898-10-28
Granted: 1899-09-02
Abstract: 22,718. Headech, E. T. Oct. 28. Drawings to Specification. Centrifugal governors.- The inclination of a swash-plate to its axis of rotation is controlled by the centrifugal action of weighted toggle-levers connected to it. One edge of the plate is connected to a fixed, and the opposite edge to a movable, part of the governor. It operates the exhaust valve of a hydrocarbon motor, and, in order that it may both open and close the valve to reduce the speed, the governor is arranged so that the plate can be forced into the normal plane from positions on either side of it by fixing the movable end of the governor and releasing the fixed end.
Patent GB-189826728-A (GB)
Title: Improvements in the Method of and Means for "Mercerising" Yarn.
Inventor: ENTWISLE JOSHUA
Filed: 1898-12-19
Granted: 1899-02-04
Abstract: 26,728. Entwisle, J., [Cohnen, B.]. Dec. 19. Yarns, mercerizing.-The yarn is subjected during the mercerizing process to an intermittent stretching operation. The hanks are preferably passed over rollers, one or both of which are formed of staves e connected by end plates c on the axle d ; or the rollers may be plain and mounted eccentrically on their axles. Any suitable apparatus may be used for effecting the mercerizing process ; for instance, the apparatus described in Specification No. 23,993, A.D. 1896, one or both of the rollers of each pair being formed in the manner above described.
Patent GB-189901374-A (GB)
Title: Improvements in Spindles for Door Handles and the like, and in Means for Attaching the same.
Inventor: SHORLAND WILLIAM BURROW
Filed: 1899-01-20
Granted: 1900-01-20
Abstract: 1374. Shorland, W. B. Jan. 20. Knobs and handles, attaching.-The spindle a to which the knob c is to be attached is divided by a longitudinal slot of wedge section. A conical-ended screw d, passing through the handle, forces the two parts of the spindle apart so as to grip the handle. The spindle may be made by doubling a piece of metal of suitable section on itself.
Patent GB-189920479-A (GB)
Title: Improvements in and relating to Odorizers.
Inventor: ETTE CHARLES GEORGE
Filed: 1899-10-12
Granted: 1899-11-18
Abstract: 20,479. Ette, C. G. Oct. 12. Flower vases.-A flower vase 9, preferably for artificial flowers, is mounted on a casing 1, in the upper chamber 4 of which sponges &c. 7, impregnated with perfumery, d i s - infectant, a n t i - septic, &c., are held by pins 6 on arms 5 of a shaft 3 driven by clockwork 2, or by an electromotor &c. Fan blades 8 on the shaft 3 cause the impregnated air to pass upwards through the top of the casing and round the vase.
Patent GB-189921712-A (GB)
Title: Device for Facilitating the Cleaning of the Types of Type-writing Machines.
Inventor: FANGOHR JOHANNES FRIEDRICH
Filed: 1899-10-31
Granted: 1899-12-30
Abstract: 21,712. Fangohr, J. F. Oct. 31. Type-writers.-Relates to devices for facilitating the cleaning of the type. For this purpose, a plate a is temporarily secured on the machine by hooks b, and the type are raised one by one through the central aperture d. Two nipping-bars f, g, pivoted at h to the plate a, and with their opposite ends guided beneath a bar e, are furnished with loopshaped handles i, k. The bars f, g are closed so as to grip the type-bar beneath the type l, and they can then be cleaned without necessitating any handling by the operator.