Patent DE-102008062965-A1 (DE)
Title: System, useful e.g. to produce a medicament to treat malignant diseases and metastatic tumors and for the isolation of a specific element of a molecular library, comprises a reaction chamber partitioned into a number of compartments
Inventor: FLAIG RUEDIGER MARCUS
IPC: C12Q1/68
Filed: 2008-12-22
Abstract: System for the isolation of a specific element E of a molecular library E1, comprises a reaction chamber partitioned into a number of compartments K 1-n, where each compartments K xapart from the physical structure of the compartment-forming components comprise (A) an element E xfrom the molecular library E1 and (B) an element M xfrom a library of physically manifested structural information M1, which is provided that to each E xbelonged to E1 at least a M xbelonged to M1 is arranged, which alone or in combination with E1 an identification and/or characterization of M xis allowed. System for the isolation of a specific element E of a molecular library E1, comprises a reaction chamber partitioned into a number of compartments K 1-n, where each compartments K xapart from the physical structure of the compartment-forming components comprise (A) an element E xfrom the molecular library E1 and (B) an element M xfrom a library of physically manifested structural information M1, which is provided that to each E xbelonged to E1 at least a M xbelonged to M1 is arranged, which alone or in combination with E1 an identification and/or characterization of M xis allowed, so that a logical connection between the E xand M xis produced by the common physical presence of E xand M xwithin a compartment. Independent claims are included for: (1) a method for providing a nucleic acid sequence and a peptide sequence, comprising using the system; (2) the nucleic acid sequence, provided by the system; (3) a polypeptide sequence, which is encoded by a nucleic acid sequence; (4) an affinity mediating molecule comprising a nucleic acid sequence or a polypeptide sequence; (5) a drug delivery system comprising the affinity mediating molecule; (6) a transgenic non-human organism comprising a nucleic acid sequence, polypeptide sequence, affinity binding molecule, or a sequence with significant homology to any of the sequences; (7) a plant comprising a transgenic non-human organism; (8) a method for producing a transgenic non-human organism, comprising obtaining the transgene using the system; (9) a method for producing nitrogenous biomass, where an organism holds under conditions, in which nitrogen deficiency is the limiting factor; (10) a method for producing biomass, hydrocarbons, polyhydroxy compounds, sugars and polyalkoxy compounds from atmospheric carbon dioxide, where an organism holds under permissive growth conditions; (11) a method for ameliorating inferior soils, comprising contacting an organism under permissive growth conditions with the inferior soils; (12) a method for the treatment of waste water, comprising contacting an organism under permissive growth conditions with the waste water; (13) a method for producing nut protein, comprising expressing the nut protein in an organism; (14) a method for reducing hydrophobic contaminants in natural habitats, comprising contacting the organism with the habitat; (15) a method for combating mosquitoes, comprising contacting an organism with the habitat of the mosquito larvae; (16) a method for combating trematodes, comprising contacting an organism with the habitat of an invertebrate, aquatic intermediate hosts of trematodes; (17) a food for animals or humans, where the raw material is produced or comprises an organism; (18) a paper, cardboard, corrugated cardboard, pulp, carton or wool, where the underlying cellulose is obtained from an organism; (19) a fuel or propellant, fuel- or propellant-additive or lubricant, and a plastic material, where the carbon source comprises an organism; (20) a method for the irrigation of farmland, where an organism holds in an open irrigation system; (21) a method for determination of the activity of a chaperone; (22) a method for producing a transgenic plant cell, where the transgenic plant cell is a transgenic organism and comprises the method of the identification of a chaperone; (23) a method (A) for in vitro identification of the resistance of a transgenic cell against irreversible inactivation by at least one abiotic stress factor compared to the wild-type cell-enhancing nucleic acid- or polypeptide sequence; (24) a liposome, obtained by the method (A); (25) a pharmaceutical formulation comprising the liposome; (26) a transgenic plant cell, produced by the method or a progeny of cell produced by division, budding or fusion; (27) a method (B) for reducing the carbon dioxide concentration in a gas stream, comprising contacting the gas stream directly or indirectly to an organism; (28) a method for the neutralization of acid in an aqueous medium, comprising contacting the aqueous medium with an organism; (29) a method (C) for the degradation of waste containing hydrocarbons, comprising contacting an organism comprising a cell with the waste; (30) an apparatus for pollution control, comprising an organism or which implements a method (B); (31) a device for providing heat or electricity, comprising the apparatus; and (32) an appliance for disposal of waste, which implements a method (C). ACTIVITY : Antiinflammatory; Cytostatic; Immunosuppressive; Cardiovascular-Gen.; Neuroprotective; Nootropic. MECHANISM OF ACTION : None given.