baber/WOPTO huggingface dataset:
Patent AT-E345433-T1 (AT)
Inventor: GERSDORF OLIVER
IPC: E05C9/00
Filed: 1999-06-02
Granted: 2006-12-15
Abstract: The invention relates to a drive rod fitting comprising a corner deflection element for drive rods which are guided in a groove for receiving the fitting, which groove runs around the sash frame. The drive rods are joined together at the sash corner via a deflection member (15) which is guided in an angular guide channel (1) situated in the groove designed for receiving the fitting. An external sash corner covering element which covers the groove for receiving the fitting can be joined to the shaped sash frame and the corner deflection element can be fastened to the sides of said groove in a positive and/or non-positive fit via a fixing device. The aim of the invention is to produce a corner deflection element in a simple manner and to simplify the subsequent assembly of the drive rod fitting. It also aims for the attachment to be sufficiently strong, using the simplest possible measures, and for it to be possible to attach the fixing device to corner deflection elements which do not have an only laterally open angular space but only have a cover rail assigned to one leg of the sash. To this end the positive and/or non-positive fit is achieved by a fixing device (20) positioned at the level of the guide channel (1).
Patent AT-E361063-T1 (AT)
Inventor: KATO IKUNOSHIN
IPC: A23K1/16
Filed: 1999-08-03
Granted: 2007-05-15
Abstract: A method of rearing useful organisms such as cultured animals which is effective in preventing the organisms from diseases, treating the organisms for diseases or maintaining the health of the organisms, characterized by administering to the organisms (1) a product of heat treatment of at least one compound selected from the group consisting of (a) uronic acid and uronic acid derivatives, (b) sugar compounds containing uronic acid and/or uronic acid derivatives and (c) substances which contain sugar compounds containing uronic acid and/or uronic acid derivatives, (2) 4,5-dihydroxy-2-cyclopenten-1-one represented by formula (I), and/or (3) a 4,5-dihydroxy-2-cyclopenten-1-one derivative; and feeds effective therein. <CHEM>
Patent AT-E219690-T1 (AT)
Inventor: TETREAULT STEPHANE
IPC: A61F13/00
Filed: 1999-07-28
Granted: 2002-07-15
Abstract: A biocompatible monomer composition includes: (A) at least one monomer, which forms a medically acceptable polymer, (B) at least one plasticizing agent present in the composition in an amount of from 0.5 wt. % to 15 wt. % of the composition; and (C) at least one acidic stabilizing agent having a pKa ionization constant of from about 1 to about 7. The composition can be applied to a variety of materials and is particularly suitable as in vivo tissue adhesive. A method of joining together in vivo two surfaces, e.g., body tissues, includes (a) holding damaged tissue edges together to form abutted tissue surfaces; (b) applying to the abutted tissue surfaces an excessive amount of a composition containing 1) at least one monomer, which forms a medically acceptable biodegradable polymer, 2) at least one plasticizing agent; and 3) at least one acidic stabilizing agent; and (c) maintaining the surfaces in contact until the composition polymerizes to form a thick film of polymerized composition bridging the abutted tissue surfaces.
Patent AT-E292548-T1 (AT)
Inventor: CLAUZURE ANDRE
IPC: B27K7/00
Filed: 1999-08-11
Granted: 2005-04-15
Abstract: The invention concerns a method for treating a cork-based product useful for making stoppers. The invention is characterised in that it comprises the following steps: a) introducing the product in a sealed container; b) subjecting said product to the action of water vapor under pressure ranging between 2.105 and 30.105 Pa for a duration ranging from about 5 seconds to 5 minutes; c) producing an expansion to restore atmospheric pressure inside the container; d) recuperating the treated product.
Patent AT-E217388-T1 (AT)
Inventor: ROUSSEAU PHILIPPE
IPC: F01N3/037
Filed: 1999-10-01
Granted: 2002-05-15
Abstract: The invention concerns a device for extracting solid particles from the exhaust gases of engines comprising a centrifuging chamber (1) equipped with a rotor (2) and a particle collector. Said device for extracting particles is characterised in that the rotor (2) of the centrifuging chamber is coupled with the shaft (11) of a turbine (7) arranged upstream of the centrifuging chamber (1), at least one chamber forming a buffer zone being provided between the turbine (7) and the centrifuging chamber (1). The invention is useful for purifying exhaust gases of heavy vehicles.
Patent AT-E254943-T1 (AT)
Inventor: SHAIKH AMER
IPC: A61M16/04
Filed: 1999-09-15
Granted: 2003-12-15
Abstract: An intubation device comprises an airway tube (10) a distal end of which is surrounded by an inflatable cuff (12) which is shaped and dimensioned to lie, in use, between the soft palate and the laryngeal inlet posteriorly of the palatopharyngeal folds. When inflated the cuff (12) has roughly the shape of the frustum of a four-sided pyramid with rounded corners and tapers away from its distal end. The distal end of the tube (10) is recessed ID into the distal end of the cuff so that the latter is an annular protrusion (13) adapted to straddle the upper region of but not to surround the elliptical epiglottis (14) and to fill the piriform fossae (15) on either side thereof.
Patent AT-E243889-T1 (AT)
Inventor: OUDALOV IOURI BORISOVITCH
IPC: H01S3/036
Filed: 1999-10-04
Granted: 2003-07-15
Abstract: The present invention relates to a CO2 laser with a gold-comprising catalyst applied substantially over the entire length of the excitation cavity. The CO2 laser contains a gas comprising carbon dioxide and carbon monoxide. According to the invention, the molar ratio of carbon monoxide to carbon dioxide is at least 0.3. This is shown to shorten the starting-up time of the laser.
Patent AT-E270525-T1 (AT)
Inventor: SCHINO MICHEL DI
IPC: A61B17/56
Filed: 1999-12-16
Granted: 2004-07-15
Abstract: The invention applies to the field of medicine, particularly to bone surgery. The invention relates to a monolateral orthopedic external fixation device for immobilizing a fractured bone having a rigid support, at least two pins screwed into the bone and joined to the rigid support by a connecting mechanism comprising a pin-holding device composed of two identical parts forming a clamp whose two opposing faces have depressions. These depressions are able to receive and hold pins with diameters from 3 to 6 mm.
Patent AT-E239880-T1 (AT)
Inventor: TONNDORFF AGGE JAN
IPC: F04D29/043
Filed: 1999-12-06
Granted: 2003-05-15
Abstract: A piston or plunger is made by passing an annular sealing member blank around a piston body and by moving it towards a central outer cylindrical surface part of the piston body defined between first and second circular edges. The sealing member blank is deformed into tight engagement with the central outer cylindrical surface part and into grooves or depressions formed therein. In this manner, a tubular sealing member, which extends axially along the central outer surface part, and which has opposite first and second ends extending beyond the first and second circular edges, respectively, is formed. Thereby both of these opposite end portions of the tubular sealing member may function as sealing lips.
Patent AT-E299754-T1 (AT)
Inventor: BURATTIN PAOLO
IPC: B01J31/28
Filed: 1999-12-21
Granted: 2005-08-15
Abstract: Hydrocyanation catalysts comprising aqueous solutions of at least one water-soluble phosphine and nickel values, well suited for the hydrocyanation of ethylenically unsaturated organic compounds such as diolefins, olefinic nitrites and monolefins, are produced by (a) admixing an aqueous solution of such at least one water-soluble phosphine with a nickel hydroxide, (b) adding hydrogen cyanide or a compound which generates hydrogen cyanide to the mixture thus formed, (c) stirring the resulting mixture until the nickel values have at least partially dissolved, and (d) reducing at least a portion of said nickel values having an oxidation state of greater than zero to the zero oxidation state.
Patent AT-E368111-T1 (AT)
Inventor: ITO TAKASHI
IPC: A61K38/00
Filed: 1999-12-08
Granted: 2007-08-15
Abstract: The betacellulin mutein or its salt of the present invention is useful for better therapeutic drug for diabetes, since they have intact BTC activity and reduced EGF activity, and no antigenicity-related problems.
Patent AT-E316730-T1 (AT)
Inventor: PRESTON DAN A
IPC: H04L12/56
Filed: 1999-11-02
Granted: 2006-02-15
Abstract: The invention provides for conversion of latitude and longitude to an addressing scheme that supports current TCP/IP (Ipv4) and future addressing (Ipv6/Ipng) requirements. More specifically, it allows a decentralization of the unicast point to a device on the hosted network. Geographical Internet Protocol (geoIP) addressing will facilitate anycast routing schemes in which the nearest node has a statically assigned geoIP. Geo-routing and network management become a function of the geoIP address.
Patent AT-E375136-T1 (AT)
Inventor: SIERRI GIANCARLO
IPC: A61F13/494
Filed: 1999-12-21
Granted: 2007-10-15
Abstract: A disposable absorbent article adapted to form a tridimensional shape before use with a generally upwardly convex rear region, having a body facing surface and a garment facing surface, a longitudinal symmetry plane, a front end edge and a rear end edge, and comprising a liquid pervious topsheet, a backsheet joined to said topsheet and an absorbent core intermediate the backsheet and the topsheet. The disposable absorbent articles of the present invention are preferably applied directly to the user's body, and comprise improved side features which extend laterally and are capable of staying in close contact with the user's inner thigh area, and adjacent to that, when the disposable absorbent article is applied to the user's body. <IMAGE>
Patent DE-106594-T1 (DE)
IPC: F16D25/12
Filed: 1983-09-28
Abstract: A hydraulically engaged clutch comprises an actuating chamber wherein pressurized hydraulic fluid acts on a piston (40) to engage the clutch and a clutch chamber (26) for clutch cooling fluid which cools the stack of discs (32, 34). A spool valve (64) in a radial passage (60) in the clutch housing controls flow of cooling fluid to the clutch chamber (26) and is acted upon by the pressure in the actuating chamber to keep the valve open while clutch-engaging pressure is supplied from a pump (42). The spool (64) is also acted on by centrifugal force to close the valve when pressure in the actuating chamber falls sufficiently. The clutch chamber then drains through a passage (66) in order to avoid viscous drag. Preferably the valve (64) moves to the open position, as pressure rises in the actuating chamber before the piston (40) engages the clutch, in order to ensure cooling during engagement.
Patent DE-683956-T1 (DE)
Inventor: COOKSON CHRISTOPHER
IPC: H04N9/804
Filed: 1994-10-13
Abstract: A system for generating a video signal in a selected one of multiple aspect ratios from play of a disk on which is recorded a motion picture in only one aspect ratio. The disk includes a code indicative of the recorded aspect ratio, and the player has a default aspect ratio setting which can be changed by the user. Typically, the recorded aspect ratio is 16:9, center cut 4:3, pan scan 4:3, and letter box aspect ratios. The player automatically generates the appropriate video signal in accordance with both its default aspect ratio setting and the disk code.
Patent ES-2027629-T1 (ES)
Title: Dispositivo de evacuacion del agua de lavado de los filtros de material granular lavados simultaneamente con agua y aire.
IPC: B01D24/10
Filed: 1991-06-18
Abstract: DISPOSITIVO DESTINADO PARA EFECTUAR LA EVACUACION DEL AGUA DE LAVADO DE LOS FILTROS DE MATERIAL FILTRANTE GRANULAR, LAVADOS SIMULTANEAMENTE CON AGUA Y CON AIRE, TAL COMO LOS UTILIZADOS EN PARTICULAR EN EL TRATAMIENTO DEL AGUA, Y LA RECUPERACION DE LAS PARTICULAS DE MATERIAL FILTRANTE GRANULAR ARRASTRADAS POR EL AGUA DURANTE EL LAVADO, CARACTERIZADO EN QUE COMPRENDE: ADOS POR AMBAS PARTES DEL ORGANO DE RECOGIDA, DELIMITANDO EN EL INTERIOR DE LOS TABIQUES INTERNOS UNA ZONA DE RECUPERACION DEL AGUA, Y ENTRE LOS TABIQUES INTERNOS Y EXTERNOS, ZONAS DE TRANQUILIZACION DE LA CIRCULACION QUE FAVORECE LA SEPARACION, POR DECANTACION DE CO-CORRIENTE DESCENDENTE, DE LAS PARTICULAS DE MATERIAL GRANULAR Y DEL AGUA SUCIA A EVACUAR, 13) DESTINADO A EVITAR LA PERTURBACION DE LAS ZONAS ANTERIORES POR LA MEZCLA TRIFASICA AGUA-AIRE-MATERIAL GRANULAR FORMADA DURANTE EL LAVADO, COLOCADO BAJO DICHAS ZONAS Y ORIENTANDO ESTA MEZCLA HACIA UNA ZONA DE DESGASIFICACION EXTERIOR, DONDE EL AIRE ES EVACUADO ANTES DE QUE LA MEZCLA, AHORA DIFASICA, ENTRE EN LAS ZONAS DE TRANQUILIZACION/DECANTACION.
Patent ES-2105997-T1 (ES)
Title: Producto para el teñido oxidativo del cabello.
Inventor: LOWE ISOLDE
IPC: C07D231/38
Filed: 1996-10-09
Abstract: COMPUESTO PARA EL TEÑIDO OXIDATIVO DE LOS CABELLOS A BASE DE UNA COMBINACION DE REVELADOR Y ACOPLADOR, LA CUAL CONTIENE COMO REVELADOR UN DERIVADO DEL 3,4,5-TRIAMINO-PIRAZOL DE FORMULA GENERAL (I), CON R{SUP,1} = HIDROGENO, ALQUILO DE C{SUB,1}-C{SUB,4}, HIDROXIALQUILO DE C{SUB,2}-C{SUB,4} R{SUP,2} = HIDROGENO, ALQUILO DE C{SUB,1}-C{SUB,4}, HIDROXIALQUILO DE C{SUB,2}-C{SUB,4} O SUS SALES HIDROSOLUBLES FISIOLOGICAMENTE ACEPTABLES, ASI COMO NUEVOS DERIVADOS DEL 3,4,5-TRIAMINO-PIRAZOL.
Patent CY-1107818-T1 (CY)
Title: Hiv-1 tat, ή παραγωγα αυτου για προφυλακτικο και θεραπευτικο εμβολιασμο
Inventor: ENSOLI BARBARA
IPC: A61K39/21
Filed: 2007-11-29
Abstract: Η παρούσα εφεύρεση αφορά Tat σαν το δραστικό συστατικό για ένα προφυλακτικό ή/και θεραπευτικό εμβόλιο έναντι μόλυνσης HIV, τη πρόοδο προς AIDS και την ανάπτυξη όγκων και άλλων συνδρόμων και συμπτωμάτων σε υποκείμενα μολυσμένα με HIV. To Tat είναι μία βιολογικώς δραστική μορφή είτε ως ανασυνδυασμένη πρωτεΐνη, είτε πεπτίδιο, είτε ως DNA. Ειδικότερα, η εφεύρεση αφορά ένα εμβόλιο που βασίζεται επί HIV-1 Tat σαν ανοσογόνο, που εμβολιάζεται σαν DNA ή/και ανασυνδυασμένη πρωτεΐνη ή σαν πεπτίδια, μόνα ή σε συνδυασμό με άλλα γονίδια ή ιϊκά γονιδιακά προϊόντα (Nef, Rev, Gag) ή τμήματα αυτών ή σε συνδυασμό με διάφορες άνοσο ρυθμιστικές κυτοκίνες (IL-12, IL-15) ή με το γονίδιο που κωδικοποιεί μία άνοσο ρυθμιστική κυτοκίνη ή τμήμα αυτής. Tat, Nef, Rev, Gag και άνοσο ρυθμιστικές κυτοκίνες χορηγούνται τόσο σαν ένα μίγμα ανασυνδυασμένων πρωτεϊνών, πεπτιδίων ή πρωτεϊνών σύντηξης (Tat/Nef, Tat/Rev, Tat/Gag, Tat/IL-12, Tat/IL-15) όσο ως πλασμίδιο DNA.
Patent CY-1110428-T1 (CY)
Title: Χρηση της rosuvastatin (zd-4522) στη θεραπευτικη αντιμετωπιση της ετεροζυγωτικης οικογενους υπερχοληστερολαιμιας
Inventor: RAZA ALI
IPC: A61P3/06
Filed: 2008-07-07
Abstract: Η εφεύρεση δίδει μία μέθοδο για τη θεραπευτική αντιμετώπιση ετεροζυγωτικής οικογενούς υπερχοληστερολαιμίας με χορήγηση της ένωσης (Ε)-7-[4-(4-φθοροφαινυλ)-6-ισοπροπυλ-2-[μεθυλ(μεθυλσουλφονυλ)αμινο]πυριμιδιν-5-υλ](3R,5S)-3,5-διυδροξυεπτ-6-ενοϊκό οξύ ή ενός φαρμακευτικώς ανεκτού άλατος αυτής.
Patent CY-1111753-T1 (CY)
Title: Χειρουργικη κασετα με βελτιωμενο φιλτραρισμα αερα
Inventor: DOMASH DAVID M
IPC: A61M1/00
Filed: 2011-03-16
Abstract: Χειρουργική κασέτα φέρουσα φιλτρομέσο διευθετημένο σφραγιστικά μεταξύ πρώτης στιβαρής επιφάνειας και δεύτερης στιβαρής επιφάνειας εντός θαλάμου φίλτρου του περιβλήματος κασέτας προσφέρει βελτιωμένο φιλτράρισμα αέρα για την κασέτα.
Patent CY-1112044-T1 (CY)
Inventor: WIJDENES JOHN
IPC: C07K16/28
Filed: 2011-11-16
Abstract: Provided is a humanized anti-CD4 antibody which is capable of activating CD4 +  CD25 +  regulatory T cells, wherein the humanized anti-CD4 antibody comprises a sequence comprising the complementarity-determining regions (CDRs) of the mouse monoclonal anti-CD4 antibody B-F5, optionally with variations in the sequence that do not substantially affect the antibody specificity and/or affinity thereof.
Patent CY-1113465-T1 (CY)
Inventor: WELLS MARK
IPC: H01R13/646
Filed: 2012-08-07
Abstract: An electrical connection device ( 10 ) for connecting a multi-core machine cable to another electrical device comprises a body ( 12 ) having an end-face with apertures and a plurality of insulating sleeves ( 22 ) extending about the apertures and a plurality of core coupling means ( 26, 28 ) each being at least in part positioned in a respective sleeve. Each core coupling means is connectable to a respective core ( 29 ) of the machine cable and has a first contact surface ( 14 ) for connecting to a terminal of another electrical device. The device comprises a plurality of spaced apart earth coupling means ( 24 ) which surround at least a portion of respective insulating sleeves. Each earth coupling means is connectable to a respective earth potential layer ( 31 ) of the machine cable and has a second contact surface ( 32 ) for connecting to an earth-potential terminal of another electrical device so that within the electrical connection device the core coupling means are earth-potential screened from one another.
Patent CY-1116901-T1 (CY)
Title: Εμβολιο που περιλαμβανει προϊοντα συζευξης καψικου πολυσακχαριδιου streptococcus pneumoniae
Inventor: BIEMANS RALPH LEON
IPC: A61K39/09
Filed: 2015-11-10
Abstract: Η παρούσα εφεύρεση είναι στο πεδίο εμβολίων προϊόντος σύζευξης πνευμονοκοκκικού καψικού σακχαριδίου. Ειδικώς, παρέχεται μια πολυδύναμη ανοσογονική σύνθεση Streptococcus pneumoniae με διάφορα συζευγμένα καψικά σακχαρίδια από διαφορετικούς ορότυπους S. pneumoniae συζευγμένα προς 2 ή περισσότερες διαφορετικές πρωτεΐνες φορείς, όπου η σύνθεση περιλαμβάνει ορότυπου 19F καψικό σακχαρίδιο συζευγμένο προς ατοξίνη διφθερίτιδας (DT) ή CRM197, όπου προαιρετικώς το 19F είναι το μόνο σακχαρίδιο στην σύνθεση συζευγμένο προς ατοξίνη διφθερίτιδας (DT) ή CRM197.
Patent CY-1119711-T1 (CY)
Title: Νεα ενωση χρησιμη για τη θεραπεια εκφυλιστικων και φλεγμονωδων ασθενειων
Inventor: BLANC JAVIER
IPC: C07D471/04
Filed: 2017-07-24
Abstract: Αποκαλύπτεται μια ένωση η οποία έχει τύπο που αντιπροσωπεύεται με τον παρακάτω: (I). Αυτή η ένωση μπορεί να παρασκευάζεται ως φαρμακευτική σύνθεση και μπορεί να χρησιμοποιηθεί για την πρόληψη και τη θεραπεία μιας ποικιλίας καταστάσεων σε θηλαστικά συμπεριλαμβανομένων ανθρώπων, που συμπεριλαμβάνουν ως μη περιοριστικό παράδειγμα, φλεγμονώδεις καταστάσεις, αυτοάνοσες ασθένειες, πολλαπλασιαστικές ασθένειες, απόρριψη μεταμόσχευσης, ασθένειες που περιλαμβάνουν εξασθένηση του ρυθμού ανανέωσης χόνδρου, συγγενείς δυσπλασίες χόνδρου ή/και ασθένειες που συνδυάζονται με υπερέκκριση IL6.
Patent CY-1120001-T1 (CY)
Title: Στερεο μπλοκ τουαλετας
Inventor: DE PELLEGRINI FEDERICO
IPC: C11D17/00
Filed: 2018-02-21
Abstract: Περιγράφεται στερεό μπλοκ τουαλέτας που έχει μια σύνθεση που περιλαμβάνει ένα μη ιοντικό τασιενεργό που επιλέγεται από έναν ή περισσότερους πολυαλκυλαιθέρες, σε ποσότητα που κυμαίνεται από 85 έως 95%, κατά προτίμηση από 91 ως 93%, κατά βάρος όσον αφορά στο συνολικό βάρος του μπλοκ, όπου το εν λόγω μη ιοντικό τασιενεργό περιλαμβάνει μια γραμμική ή διακλαδωμένη αλκυλική αλυσίδα, κατά προτίμηση γραμμική, με έναν αριθμό ατόμων άνθρακα μεγαλύτερο από ή ίσο με 10 και κατά ακόμη μεγαλύτερη προτίμηση ευρισκόμενο μεταξύ 12 και 22 και όπου το εν λόγω μη ιοντικό τασιενεργό έχει έναν αριθμό γραμμομορίων οξειδίου αιθυλενίου ανά μόριο μεγαλύτερο από 15, κατά ακόμα μεγαλύτερη προτίμηση μεγαλύτερο από 30, έναν παράγοντα αρωματισμού σε ποσότητα που κυμαίνεται από 2 έως 10%, κατά προτίμηση από 3 έως 5% κατά βάρος όσον αφορά στο συνολικό βάρος του μπλοκ, πολυαλκοόλη με έναν αριθμό ατόμων άνθρακα κατά προτίμηση μικρότερο από 5 ή έναν υγρό πολυαιθέρα σε θερμοκρασία δωματίου σε ποσότητα που κυμαίνεται από 0,1 έως 3%, κατά προτίμηση από 1,5 έως 2,5% κατά βάρος όσον αφορά στο συνολικό βάρος του μπλοκ, έναν παράγοντα αφρισμού που επιλέγεται από τις κατηγορίες των ανιονικών ή/και μη ιοντικών ή/και κατιονικών ή/και επαμφοτεριζόντων τασιενεργών, σε ποσότητα που κυμαίνεται από 1 έως 3%, κατά προτίμηση από 1,5 έως 2,5% κατά βάρος όσον αφορά στο συνολικό βάρος του μπλοκ, νερό σε ποσότητα που κυμαίνεται από 0,1 έως 0,5%, κατά προτίμηση από 0,2 έως 0,3%, κατά βάρος όσον αφορά στο συνολικό βάρος του μπλοκ, με την εν λόγω σύνθεση να προβλέπει ένα ανόργανο ή οργανικό πληρωτικό παρόν σε ποσότητα μικρότερη από 20% κατά βάρος, κατά προτίμηση μικρότερη από 10% κατά βάρος, κατά ακόμη μεγαλύτερη προτίμηση χωρίς να προβλέπει κάποιο ανόργανο ή οργανικό πληρωτικό.
Patent CY-1122850-T1 (CY)
Title: Υπερδιακλαδισμενος πολυ (βητα-αμινοεστερας) για γονιδιακη θεραπεια
Inventor: WANG WENXIN
IPC: C12N15/85
Filed: 2020-04-16
Abstract: Η εφεύρεση σχετίζεται με διακλαδισμένα πολυμερή, τα οποία χρησιμοποιούνται σε εφαρμογές γονιδιακής θεραπείας ως παράγοντες διαμόλυνσης νουκλεϊκού οξέος. Πιο συγκεκριμένα, η εφεύρεση παρέχει βιοαποικοδομήσιμα, υπέρ διακλαδισμένα πολυμερή, τα οποία μπορούν να χρησιμοποιηθούν στη χορήγηση των γονιδίων και παρέχουν βελτιωμένες αποδόσεις διαμόλυνσης, οι οποίες είναι ταυτόχρονα ασφαλείς και μη τοξικές.
Patent HR-P20090294-T1 (HR)
Inventor: ABOUABDELLAH AHMED
IPC: C07D207/04
Filed: 2009-05-20
Abstract: Spoj formule (I) u kojojm predstavlja cijeli broj od 1 do 4; n predstavlja cijeli broj 1, 2 ili 3; o predstavlja cijeli broj 1 ili 2; A se bira iz jedne ili više skupina X, Y i/ili Z; X predstavlja metilensku skupinu, izborno supstituiranu s jednom ili dvije C1-6-alkilnih, C3-7-cikloalkilnih ili C3-7-cikloalkil-C1-3-alkilenskih skupina; Y predstavlja bilo C2-alkenilensku skupinu, izborno supstituiranu s jednom ili dvije C1-6-alkilnih, C3-7-cikloalkilnih ili C3-7-cikloalkil-C1-3-alkilenskih skupina; ili C2-alkinilensku skupinu; Z predstavlja skupinu formule: gdjep predstavlja cijeli broj od 1 do 5; q i r predstavljaju cijele brojeve, a tako su definirani da r + p je broj od 1 do 5; B predstavlja kovalentnu vezu ili C1-6-alkilensku skupinu; G predstavlja kovalentnu vezu, atom kisika ili sumpora ili skupinu -CH(OH)-, CO, SO ili SO2;R1 predstavlja skupinu R4, izborno supstituiranu s jednom ili više skupina R5 i/ili R6;R4 predstavlja skupinu koju se bira između furanila, pirolila, tienila, oksazolila, izoksazolila, tiazolila, izotiazolila, imidazolila, pirazolila, tiadiazolila, izotiadiazolila, oksadiazolila, tiadiazolila, triazolila, tetrazolila, fenila, piridinila, piridazinila, pirimidinila, pirazinila, triazinila, naftalenila, kinolinila, tetrahidrokinolinila, izokinolinila, tetrahidroizokinolinila, ftalazinila, kinazolinila, kinoksalinila, cinolinila, naftiridinila, imidazopirimidinila, tienopirimidinila, benzofuranila, dihidrobenzofuranila, benzotienila, dihidrobenzotienila, benzimidazolila, benzoksazolila, benzizoksazolila, benzotiazolila, benzizotiazolila, indolila, izoindolila, indazolila, pirolopiridinila, furopiridinila, dihidrofuropiridinila, tienopiridinila, dihidrotienopiridinila, imidazopiridinila, pirazolopiridinila, oksazolopiridinila, izoksazolopiridinila, tiazolopiridinila; R5 predstavlja atom halogena, skupinu cijano, nitro, hidroksilnu, C1-6-alkilnu, C1-6-alkoksi, C1-6-tioalkilnu, C1-6-fluoralkilnu, C1-6-fluoralkoksi, C1-6-fluortioalkilnu, C3-7-cikloalkilnu ili C3-7-cikloalkil-C1-3-alkilensku skupinu ili skupinu NR7R8, NR7COR8, NR7CO2R8, NR7SO2R8, COR7, CO2R7, CONR7R8, SO2R7, SO2NR7R8 ili -O-(C1-3 alkilen)-O-;R6 predstavlja fenilnu, feniloksi, benziloksi, piridinilnu, pirazinilnu, piridazinilnu, pirimidinilnu ili pirimidiniloksi skupinu; jedna ili više skupina R6 mogu biti supstituirane s jednom ili više međusobno istovjetnih ili različitih skupina R5;R7 i R8 međusobno neovisno predstavljaju atom vodika ili C1-6-alkilnu skupinu, ili, s atomom odnosno atomima koji ih nose, tvore prsten kojeg se bira između azetidinskog, pirolidinskog, piperidinskog, morfolinskog, tiomorfolinskog, azepinskog ili piperazinskog prstena, gdje je taj prsten izborno supstituiran s C1-6-alkilnom ili benzilnom skupinom; R2 predstavlja atom vodika ili C1-6-alkilnu skupinu; R3 predstavlja atom vodika ili C1-6-alkilnu, C3-7-cikloalkilnu ili C3-7-cikloalkil-C1-3-alkilensku skupinu; u obliku baze, adicijske soli s kiselinom, hidrata ili solvata. Patent sadrži j