baber/WOPTO huggingface dataset:
Patent PT-1685829-E (PT)
Title: Use of (1rs,3rs,6rs)-6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol for treating inflammatory pain
Inventor: ELMAR FRIDERICHS DR
IPC: A61K31/135
Filed: 2003-11-18
Abstract: Mixture (X) of at least one analgesic (A) and an inhibitor (B) of cyclo-oxygenase II (COXII). Mixture (X) of at least one analgesic (A) and an inhibitor (B) of cyclo-oxygenase II (COXII), where (A) is a phenyl-substituted tertiary amine of formulae (I)-(III), as racemates, pure or mixed stereoisomers (particularly enantiomers or diastereoisomers), optionally in the form of acids, bases, salts or solvates, preferably hydrates. [Image] X : hydroxy, fluoro, chloro, hydrogen or OCOR 7>; R 1>1-4C linear, branched, saturated or unsaturated alkyl, optionally substituted one or more times, in (I), or 1-4C alkyl, benzyl, trifluoromethyl, hydroxy, benzyloxy. 1-3C alkoxy, chloro or fluoro in (II); R 2> and R 3>hydrogen or 1-4C alkyl (as for R 1>) or together form an optionally substituted 4-7C cycloalkyl; R 9>-R 1> 3>hydrogen, fluoro, chloro, bromo, iodo, (di)fluoromethyl, trifluoromethyl, hydroxy, thiol, OR 1> 4>, trifluoromethoxy, SR 1> 4>, NR 1> 7>R 1> 8>, (trifluoro)methyl- sulfinyl or -sulfonyl, cyano, COOR 1> 4>, nitro, CONR 1> 7>R 1> 8>, 1-6C alkyl (as above) or phenyl, optionally substituted one or more times; R 1> 4>1-6C alkyl, pyridyl, thienyl, thiazolyl, phenyl, benzyl, phenethyl (all optionally substituted one or more times), PO(O-1-4C alkyl)-2, COO1-5C alkyl, CONH(1-3C alkylphenyl), CO(1-5C)alkyl, COCHR 1> 7>-NHR 1> 8>, or CO-phenylene-R 1> 5>; R 1> 5>ortho-OCO(1-3C)alkyl, or meta- or para-CH 2N(R 1> 6>) 2; R 1> 6>1-4C alkyl or morpholino, and all alkyl in R 1> 4>-R 1> 6> are optionally substituted one or more times; R 1> 7> and R 1> 8>hydrogen, 1-6C alkyl (as above), phenyl, benzyl or phenethyl, all optionally substituted one or more times; R 1> 0> with either of R 9> or R 1> together : a OCH 2O, OCH 2CH 2O, OCH=CH, CH=CHO, CH=CMeO, OCMe=CH, (CH 2) 4 or OCH=CHO ring; proviso: in (III), when R 9>, R 1> 1> and R 1> 3> are all hydrogen, one of R 1> 0> and R 1> 2> is hydrogen and the other methoxy, then X is nor hydroxy. ACTIVITY : Analgesic. In the mouse writhing test ( J. Pharmacol. Exp. Ther., 228 (1984) 1) animals were treated with (a) (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol (X); (b) rofecoxib (Y) or (c) a mixture of both at ratio 1:2, then after 30 minutes injected with acetic acid. The ED50 for reduction of writhing was 33 mg/kg for (X) alone and 60.1 mg/kg for (Y) alone, but only 23.3 mg/kg (compare 47 mg/kg for an additive effect) for the mixture. MECHANISM OF ACTION : None given.
Patent PT-1754478-E (PT)
Title: Liquid composition comprising arginine and alpha-lipoic acid and its use for improvement of sexual function
Inventor: WESSEL KLAUS
IPC: A61P15/10
Filed: 2005-08-04
Abstract: The present invention relates to solid compositions comprising a substance which improves nitric oxide (NO) availability, re. an NO donor or a precursor of the biosynthesis of nitric oxide or an direct or indirect NO agonist, with arginine being a preferred compound, in combination with a dithiolane, with ±-lipoic acid as a preferred compound, and its use for improvement of sexual function. The compositions according to the invention comprise the NO donor or its precursor in excess, based on the molar amount of the constituents. The compositions are also suited for the improvement of sexual function. In particular the present invention relates to the use of a dithiolane in combination with a NO donor or a precursor thereof for the preparation of a medication for treatment of sexual dysfunction.
Patent PT-1720763-E (PT)
Title: Power supply device for a submersible vessel
Inventor: LERSCH JOSEF
IPC: B63G8/08
Filed: 2005-01-20
Abstract: The power supply system is for a submarine with at least one electrics screw motor, batteries set (3), charging generator with drive, and supply system with switching and automation devices. It has a hydrogen peroxide fuel cell device (4) consisting of individual modules which are connected to the bus bars for supplying the motor with electricity via a load switch depending on the charge state of the fuel cell device.
Patent PT-1789312-E (PT)
Title: Electroacoustic underwater antenna
Inventor: BRENNER AXEL
IPC: B63G8/39
Filed: 2005-06-15
Abstract: An electroacoustic underwater antenna, particularly a lateral antenna which can be fixed to the outer hull of an underwater craft, comprising a series of hydrophones (13) successively arranged in at least one elongate, closed, oil-filled cavity at a distance from each other. The aim of the invention is to achieve a high degree of reception sensitivity in the low frequency range with a sufficiently small, vertical aperture angle. The inventive device is easy to produce and mount and is characterized by several cavities (14) which are fitted with hydrophones (13) at a parallel distance from each other, arranged in front of a rigid plate (12) at a distance therefrom. The plate (12) and the cavities (14) are formed in a panel-type, acoustically transparent plastic element (11). Several of said plastic elements (11) are arranged close to each other or behind each other.
Patent PT-1914842-E (PT)
Title: Connector for coaxial cables
Inventor: COUCEIRO ESTEBAN CARBACIDO
IPC: H01R13/646
Filed: 2007-10-20
Abstract: The plug has a housing (1) consisting of a part (11) and another part (12), where the parts of the housing are connected with each other using a rotating unit (2). The parts have a cross section in form of a rectangle with four sides at their connecting area, and the rotating unit is arranged at one of the sides of the rectangle. A coaxial cable (5) is fed over another side of the rectangle. The parts are connected with each other in a closing position of the housing by the rotating unit and by a sealing system.
Patent PT-2047210-E (PT)
Title: Optical profile scanning
Inventor: PATKO SANDOR MATYAS
IPC: G01B11/25
Filed: 2007-07-26
Abstract: A profile of a surface of an object (12) that has a longitudinal axis is determined by arranging a camera (14) to view a portion of the surface with its viewing axis (15) substantially perpendicular to the longitudinal axis, and arranging two scanning light sources (16, 18) to define planes of illumination which define two lines on the surface, so that the camera produces an image including images of the two lines. From the separation of the two lines in the image the surface profile can be determined. The planes of illumination are preferably inclined to one another, as this can enhance sensitivity.
Patent PT-2193731-E (PT)
Title: Food container for use in microwave cooking
Inventor: HUBER LUKAS WERNER
IPC: A47J27/04
Filed: 2007-09-07
Abstract: The invention relates to a utensil for containing foodstuffs, applicable to cooking in a microwave oven, comprising a receptacle (10) made of an elastomer material with an access opening and covering means for covering said access opening. The receptacle (10) is formed by one or more walls including a bottom wall (1) in elongated channel shape and opening edges (5, 6, 8, 9) defining the access opening at a height greater than the bottom. The bottom wall (1) includes reinforcing ribs (7) projecting outwardly from an outer surface thereof and providing supports leaving most of the outer surface of the bottom wall (1) exposed to the surrounding atmosphere when the receptacle (10) is on a support surface. The bottom wall (1) is connected at its ends to end walls (2, 3) determining respective end opening edges (8, 9) configured to support lids (30, 40).
Patent PT-626898-E (PT)
Inventor: SPIRER STEVEN E
IPC: B25B13/46
Filed: 1993-12-20
Abstract: A fluid-operated tool for elongating a stud which has an axis and an end extending out over a nut, the tool comprises stud pulling unit adapted to engage the end of the stud so as to pull the stud, nut turning unit adapted to engage the nut so as to turn the nut, first fluid-operated unit acting on the stud pulling unit so that the stud pulling unit pull the end of the stud to elongate the stud, second fluid-operated unit acting on the nut turning unit so that the nut turning unit turns the nut, the first fluid-operated unit and the second fluid-operated unit communicating with a fluid source so that a pressure fluid supplied by the fluid source to the first fluid-operated unit and the second fluid-operated unit elongates the stud and turns the nut.
Patent PT-754359-E (PT)
Inventor: UGGMARK JOHAN GEORG MICHAEL
IPC: H01R13/719
Filed: 1995-03-30
Abstract: PCT No. PCT/SE95/00338 Sec. 371 Date Dec. 3, 1996 Sec. 102(e) Date Dec. 3, 1996 PCT Filed Mar. 30, 1995 PCT Pub. No. WO95/27323 PCT Pub. Date Oct. 12, 1995An elastically deformable, elastomeric connector (10) has electrically conductive elements (11a, 11b) extending in parallel between opposite ends of said connector (10). A first conducting path (13) is formed by a first set of electrically conductive elements (11a, 11b) and is substantially surrounded by a second conducting path (14) formed by a second set of electrically conductive elements connected to ground, thereby providing a shielding of said first path.
Patent PT-804079-E (PT)
Inventor: LINDNER WOLFGANG
IPC: A01N43/64
Filed: 1996-11-15
Abstract: PCT No. PCT/EP96/05037 Sec. 371 Date Sep. 24, 1998 Sec. 102(e) Date Sep. 24, 1998 PCT Filed Nov. 15, 1996 PCT Pub. No. WO97/18710 PCT Pub. Date May 29, 1997The present invention relates to an algicide combination of triazine derivatives and N,N-dialkylurea derivatives and to its use for protecting industrial products against infestation and destruction by photoautotrope microorganisms.
Patent PT-810410-E (PT)
Inventor: PROSDOCIMI JACQUES
IPC: F25B49/04
Filed: 1997-05-27
Abstract: The process begins with connection of the evaporator/condenser (14'), when filled with liquid ammonia, to the reactor (10) which contains an element (24) for reheating of the active solid. Gas is returned to the condenser through a valve (18') in the connecting pipe (16'). The reheating is commenced before the cooling of the evaporator has been completed. In a preliminary stage the reactor and its contents are prepared so as to have sufficient thermal capacity for absorption of the heat produced by the exothermic reaction.
Patent PT-897470-E (PT)
Inventor: THYBERG CONNY
IPC: F03B3/06
Filed: 1997-04-25
Abstract: PCT No. PCT/SE97/00699 Sec. 371 Date Oct. 20, 1998 Sec. 102(e) Date Oct. 20, 1998 PCT Filed Apr. 25, 1997 PCT Pub. No. WO97/41348 PCT Pub. Date Nov. 6, 1997A Kaplan turbine or similar hydraulic machine has a hub body (1) fixed to the turbine shaft with radial blades attached to the hub body. The blades are fitted with oil lubricated bearings in the hub body. A sealing arrangement for the oil system has first (60) and second (61) circumferential sealing members with a circumferential space (65) between the first and second sealing members (60, 61). High pressure water from a water source is directed into the circumferential space (65) via a connecting channel (64) to block the lubricating oil from leaking into the working fluid.
Patent PT-922832-E (PT)
Inventor: JAVEY MICHEL
IPC: E06B9/60
Filed: 1998-09-28
Abstract: The retaining mechanism for a roller shutter with metal slats, is able to roll onto one or more reels (6) turning on a fixed shaft (7) with the aid of spiral compensating springs (12) equipped with retaining members designed to stop the shutter dropping in the event of compensating spring failure. The outer end (17) of each compensating spring is connected to a locking member (20) which moves on the corresponding reel. Each locking member is able to move in the direction of a static component (30) fixed to the shaft (7) and engage with one of its teeth (35). The locking member is held at a distance from the static component by the compensating spring and moves in a direction which is substantially tangential to the reel's axis of rotation.
Patent PT-1049461-E (PT)
Inventor: KEMP COLIN ANTHONY
IPC: A61K47/44
Filed: 1999-01-28
Abstract: Glyceryl trinitrate and lanolin in combination are used in the preparation of compositions for the treatment of erectile dysfunction in human males and for a method of cosmetic treatment of human males.
Patent PT-1114166-E (PT)
Inventor: HALKIER TORBEN
IPC: A61K39/395
Filed: 1999-09-13
Abstract: The invention provides a novel method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment/amelioration of diseases characterized by excessive loss of bone mass, e.g. osteoporosis. Down-regulation is effected by inducing an immune response against OPGL in an individual in need thereof. Immune responses can be raised by classical immunization with immunogenic variants of OPGL or by nucleic acid immunization where the nucleic acids encode the OPGL variant. The invention also pertains to compositions, polypeptides and nucleic acids useful in the invention, as well as to vectors and transformed host cells useful in the preparation thereof.
Patent PT-1123429-E (PT)
Inventor: REBOUILLAT SERGE
IPC: C08L101/00
Filed: 1999-10-06
Abstract: Poly(p-phenylene terephthalamide) fibers are disclosed which have been grafted with nitrobenzyl, allyl, or nitrostilbene groups to increase adhesion of the fibers to rubber. A process for making the grafted fibers is, also, disclosed.
Patent SG-69293-G (SG)
Title: Oral hygiene compositions
IPC: A61Q11/00
Filed: 1993-05-27
Abstract: An oral hygiene composition containing an effective concentration of a pharmaceutically acceptable fluoride salt, a pharmaceutically acceptable zinc salt, a specific buffering agent a suitable vehicle and having a pH of from about 3.5 to 6.0.
Patent SG-95290-G (SG)
Title: Chromatographic device having modified edges and diagnostic kit incorporating it
IPC: G01N30/92
Filed: 1990-11-21
Abstract: A chromatographic material for use in a chromatographic system wherein a component of a mixture is partitioned between a liquid phase and an immobile phase, the component traversing at least a portion of the chromatographic material. The chromatographic device generally has at least one longitudinal edge substantially corresponding to the direction of traverse of the component, and the longitudinal edge includes means, such as indentations or a chemical substance, for controlling the shape of the front of the traversing component.
Patent IE-890146-L (IE)
Title: Security printing process
IPC: B41M3/14
Filed: 1989-01-18
Abstract: Method for preventing or reducing the likelihood of successful alteration of information printed on a document, wherein a detectable substance is released from ruptured microcapsules onto the document in image areas. The substance penetrates through the document to form a confirming image on the reverse surface. Another detectable substance of lesser penetrating ability simultaneously may be released onto the document in the image areas. Spreading of the first substance outside the boundaries of the image area created by the second substance may produce a halo effect around the image area. Documents as treated by the methods are disclosed, as well as articles comprising a document to be treated in contact with a sheet coated with the detectable substance. The first substance is microencapsulated, the second substance may or may not be microencapsulated.
Patent IE-39121-L (IE)
Title: Chocolate compositions.
IPC: A23G1/00
Filed: 1974-04-08
Abstract: 1430017 Chocolate crumb composition UNILEVER Ltd 10 April 1974 [13 April 1973] 17962/73 Heading A2B A milk chocolate crumb composition comprises non-fat milk solids, sugar, cocoa mass or powder and non-milk edible fat compatible with cocoa butter. The amount of edible fat should preferably be equal to the total fat in a crumb based on full cream milk. It may be in the form of cocoa butter, a palm oil fraction, fats from vegetable butters or lauric fats from palm kernel and coconut oil. Lecithin may be added as an emulsifier.
[GB1430017A]
Patent IE-900980-L (IE)
Title: Intraoral medication releasing system
IPC: A61K9/22
Filed: 1990-03-16
Abstract: A system for long term releasing of medication in the mouth, and especially an intra-oral fluoride releasing system (IFRS) for releasing fluoride over a long term for inhibiting the formation of caries in the teeth. The system uses a holder (10,130) for retaining and protecting intra-oral fluoride tablets (100) or other intra-oral medicament in the form of fluoride releasing devices (IFRD). The holder (10,130) has a plate (30) with retaining sides (40,140) and retaining posts (50,150,155) or a carrier. The tablet (100) will fit within the holder (10,130). The tablet (100) may be located in the carrier, or ligature bands (200) can be tied around the tablet (100) in order to releasably hold the IFRD within the holder (10,130). The system causes a level of fluoride to be maintained over a long term within the mouth which has been found chemically effective for caries control and without causing severe irritation to oral tissues.
Patent FI-810743-L (FI)
Inventor: SCHARWAECHTER PETER
IPC: C07D249/08
Filed: 1981-03-10
Abstract: 1. A 1,1-diphenyl-2-(1,2,4-triazol-1-1-yl)-ethanol of the general formula I  see diagramm : EP0036153,P8,F1  where one of the radicals R**1, R**2 and R**3 is chlorine and the others, which may be identical or different, are hydrogen or chlorine, and its pharmacologically tolerated salts as antimycotics.
Patent FI-821253-L (FI)
Inventor: EINIG HEINZ
IPC: A61K9/54
Filed: 1982-04-07
Abstract: 1. A pharmaceutical composition which contains a calcium-antagonistic active compound, with or without additional active compounds, is intended for oral administration to produce a sustained action for continuous therapy and contains only the sustaining dose of active compound, bound to pharmaceutical auxiliaries, wherein the calcium-antagonistic active compound is Gallopamil or Verapamil and wherein, at the sustaining dose, the ratio of the constituents with rapid release of active compound to those with sustained release of active compound is from 1 : 0.6 to 1 : 6.
Patent FI-823975-L (FI)
Inventor: BECHGAARD HELLE
IPC: A61K9/22
Filed: 1982-11-19
Abstract: A pharmaceutical oral controlled release multiple-units formulation in which individual units comprise cross-sectionally substantially homogeneous cores containing particles of a sparingly soluble active substance, the cores being coated with a coating which is substantially resistant to gastric conditions, but which is erodable under the conditions prevailing in the small intestine, in particular an enteric coating which is substantially insoluble at a pH below 7 such as Eudragit<sup>0</sup> S (an anionic polymerisate of methacrylic acid and methacrylic acid methyl ester), is prepared by a process comprising comminuting an active substance together with a substance which is readily soluble in intestinal fluids such as an anionic detergent to obtain particles containing the active substance in intimate admixture with the readily soluble substance, combining the resulting particles into cross-sectionally substantially homogeneous cores together with components which accelerate the disintegration of the cores in intestinal fluids such as talc and sucrose, coating the individual cores with the coating, and combining a multiplicity of the coated cores into a capsule or tablet formulation.As the coating is erodable in an alkaline environment only, the active substance is not released until the units arrive at a section ofthe small intestine with an alkaline pH. Thus, a reduction and delay of the peak plasma concentration is obtained without affecting the extent of drug availability.A coating of the above-defined type may also be used when the active substance is a substance which exerts an irritating effect on the gastric mucosa and/or is unstable in an acidic environment.
Patent FI-831436-L (FI)
Inventor: ENGELSBERGER HERBERT
IPC: B32B27/32
Filed: 1983-04-27
Abstract: 1. Multi-layer film comprising a single- or mul-.
Patent FI-844394-L (FI)
Inventor: HARRIS GREGORY DAVID
IPC: C07D307/20
Filed: 1984-11-08
Abstract: The invention provides a novel process for the manufacture of [2,3-trans]-tetrahydro-5-hydroxy-3-hydroxymethyl-2-phenylfurans of the formula IIa, useful as intermediates in the production of novel (4-phenyl-1,3-dioxan-cis-5-yl)alkenoic acids of the formula I in which Ra and Rb are independently hydrogen, alkenyl, alkyl, halogenoalkyl, pentafluorophenyl, aryl or aryl-(1-4C)alkyl; or Ra and Rb together are polymethylene; Rc is hydroxy or (1-6C)alkanesulphonamido, A is vinylene, n is 1, Y is polymethylene, and benzene ring B bears various optional substituents. The compounds of formula I are obtained by the reaction of an aldehyde of formula II with an ylid to give an erythro-diol of formula III which is then cyclised to the required dioxane derivative of formula I. The aldehydes of formula II are obtained from the corresponding lactols of formula IIa, which are themselves obtained with the correct trans-stereochemistry by the inventive process using two selective reductions of a trans-phenylparaconic acid of formula V. The compounds of formula I are useful as therapeutic agents.
Patent IE-781011-L (IE)
Title: Push-in pressure releasing closure in container closure¹member and method of manufacture
IPC: B21D51/44
Filed: 1978-05-19
Abstract: A push-in pressure releasing resealable closure for an aperture in a sheet metal container member is disclosed, wherein the closure is integral through a connection of metal to the remainder of the container member. The closure is designed so that it is depressible into the container by flexing about the connection when push-in force is applied to the closure, without exceeding the elastic limit of the connection, so that the closure is returned at least substantially to its original position to seal the can contents, upon removal of the push-in force from the closure. The closure is particularly suitable for use in containers for carbonated beverages, such as carbonated soft drinks and beer, so that the gas pressure within the container may be released without danger of substantial gushing or spurting, to permit a larger pouring opening in the container member to be opened. The specification discloses several embodiments of the pressure releasing closure including one in which the closure is formed partly within a pouring closure and partly outside said pouring closure whereby the pressure releasing closure is permanently opened by the opening of said pouring closure to create an air vent or liquid draining opening outside the pouring closure. The specification also discloses methods of forming closures in which the number of forming stages is reduced. In one method, the closure piercing operating is performed at the same time as the edge of the tab is downwardly reformed. In another method, the sheet metal around the opening is also reformed in the same operation.
[EP0000091A1]
Patent IE-821174-L (IE)
Title: Microbial gene promoter/operator
IPC: C12N15/72
Filed: 1982-05-17
Abstract: Hybrid promoter/operators are prepared and inserted into plasmids which are used to transform E. coli. They are arranged to control expression (by a gene in the plasmid) of a desired heterologous peptide e.g. human growth hormone, HGH. Each hybrid promoter/operator has (a) a promoter operator fragment which is capable of being chemically induced, and (b) a fragment which includes the -35 consensus sequence and the 5 min flanking region thereof of a promoter having a high signal strength. The fragments (a) and (b) are appropriately spaced to form an operable hybrid promoter which is both inducible and of high signal strength (properties not naturally found together). E.g. one hybrid operator/promoter has a sequence from upstream of position -22 of the trp promoter (of high strength) coupled to a sequence downstream from position -19 of the lac promoter operator (inducible). This was used to control a gene for HGH in a plasmid pHGH807tacl. E. coli was transformed therewith and cultured. Production of HGH (rapid owing to the strong promoter fragment) was induced by addition of isopropyl- beta -D-galactoside to the culture medium.
[EP0067540A2]