baber/WOPTO huggingface dataset:
Patent EP-4263867-A1 (EP)
Inventor: KOUMBARIS GEORGE
IPC: C12Q1/6876
Filed: 2021-12-16
Abstract: The disclosure provides methods and kits for the classification of biological samples into clinically relevant categories. The method is a method of classifying a sample as comprising cell-free tumor DNA, the method comprising the steps of:(i) determining in a sample comprising a plurality of cell-free DNA (cfDNA) fragments the sequence coordinates of the start and/or stop of at least 100,000 cfDNA fragments by alignment to a reference sequence, (ii) determining in the reference sequence all nucleic acid motifs comprised of trinucleotides, tetranucleotides and pentanucleotides:a) within the range of 1 to 5 base pairs inwards but adjacent to each start and/or stop sequence coordinate determined in (i), and/orb) within a range of 1 to 5 base pairs outwards but adjacent to each start and/or stop sequence coordinate determined in (i),(iii) determining the frequency of:a) each sequence coordinate plus and/or minus 1 base pair determined in (i) in the plurality of cfDNA fragments comprised in the sample, b) each of the nucleic acid motifs determined in (ii) a) and b) in the plurality of cfDNA fragments comprised in the sample, (iv) calculating the ratio of each of the frequencies determined in (iii) a) and b) over a corresponding reference frequency, (v) calculating a diagnostic score separately for each ratio determined in step (iv), said score being the respective weighted sum of all respective frequency ratios of step (iv) (vi) calculating a combined diagnostic score from at least two or more of the diagnostic scores determined in (v) said score being the weighted sum of said two or more diagnostic scores determined in (v), and(vii) determining a classification of the sample by comparing the combined diagnostic score to a reference score, NIPD GENETICS PUBLIC COMPANY LIMITED CH Kilger Anwaltspartnerschaft mbBCyprus Fasanenstraße 29Our Ref.: B281-0029WO1 10719 Berlinwherein the sample is classified as comprising tumor cfDNA, if the combined diagnostic score value is higher than the mean of the reference score by at least one standard deviation of the reference score, wherein the reference score is calculated from one or more reference values.
Patent EP-4057234-A1 (EP)
Title: Method and apparatus for constructing three-dimensional facial model, and device and storage medium
Inventor: LIN XIANGKAI
IPC: G06T17/00
Filed: 2021-06-01
Abstract: Embodiments of this application disclose a method and an apparatus for constructing a three-dimensional face model, a device, and a storage medium, which belong to the field of computer vision technologies of artificial intelligence. The method includes: obtaining a face point cloud of a target object; determining, through expansion calculation, pixel coordinates on a face texture image of the target object that correspond to 3D data points in the face point cloud, to obtain index information of the 3D data points; performing triangulation on pixels on the face texture image to obtain triangulation information; obtaining an initial 3D face model according to the triangulation information, the index information, and the face point cloud; determining a non-critical region in the initial 3D face model; smoothing the non-critical region in the initial 3D face model to obtain a smoothed non-critical region; and replacing the non-critical region in the initial 3D face model with the smoothed non-critical region to obtain a 3D face model of the target object. Embodiments of this application improve the efficiency of 3D face reconstruction.
Patent EP-4268282-A1 (EP)
Title: Integration d'un circuit de detection a base de resonateurs optiques sur un circuit de lecture d'un imageur
Inventor: DELGA ALEXANDRE
IPC: H01L27/146
Filed: 2021-12-21
Abstract: L'invention a pour objet un dispositif optoélectronique comprenant au moins un pixel, chaque pixel comprenant un résonateur optique comprenant une structure photo-détectrice confinée entre une couche métallique réflectrice et une seconde couche métallique réflectrice; et un circuit intégré de lecture disposé sur un substrat et comprenant au moins une électrode de lecture enterrée dédiée au pixel et au moins une couche externe métallique ou diélectrique. L'ensemble comprenant au moins la couche métallique réflectrice et la couche externe du circuit intégré de lecture est dénommé structure planaire d'assemblage. La première couche métallique est connectée à l'électrode de lecture au moyen d'un via métallique traversant la structure du résonateur optique et la structure planaire d'assemblage. Le via métallique est électriquement isolé de la structure photo détectrice et de la structure planaire d'assemblage.
Patent EP-4271185-A1 (EP)
Inventor: HELLAL HOCINE
IPC: A01N25/08
Filed: 2021-12-29
Abstract: La présente invention concerne un système de distribution comprenant un premier hydromagnésite, le premier hydromagnésite étant un hydromagnésite non chargé, et un deuxième hydromagnésite, le deuxième hydromagnésite étant chargé avec au moins un principe actif.
Patent EP-4267600-A1 (EP)
Title: Mutéines d'il-2 pour le traitement de maladies autoimmunes et inflammatoires
Inventor: ALVES STEPHEN E
IPC: C07K14/55
Filed: 2021-12-21
Abstract: La présente invention concerne des mutéines d'IL-2 qui se lient à la sous-unité du récepteur d'IL-2, mais ne présentent pas de liaison mesurable à la sous-unité de récepteur d'IL-2. L'invention concerne également des compositions, des kits, des méthodes et des utilisations faisant intervenir de telles mutéines d'IL-2.
Patent EP-4186923-A1 (EP)
Title: Anti-henipavirus monoclonal antibody having broad spectrum neutralization activity and use thereof
Inventor: CHEN WEI
IPC: C07K16/10
Filed: 2021-06-27
Abstract: Provided is an anti-Henipavirus monoclonal antibody having broad spectrum neutralization activity, wherein the antibody comprises a macaque variable region and a human constant region. The antibody of the present invention has good binding activity to both Nipah virus glycoprotein G and Hendra virus glycoprotein G, can effectively neutralize Nipahpseudovirus and Hendra pseudovirus, and can be used for preparing drugs for treating Henipavirus diseases.
Patent EP-4263555-A1 (EP)
Inventor: PENNINGTON LEWIS D
IPC: C07D498/04
Filed: 2021-12-21
Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
Patent EP-4204639-A1 (EP)
Inventor: YOCIUS DANIEL
IPC: B29C44/20
Filed: 2021-08-27
Abstract: Methods and systems for manufacturing a foam board system are disclosed. In some examples, a system includes an applicator to distribute one or more fluids onto a substrate. One or more sensors configured to measure one or more characteristics of the one or more fluids. A control circuitry is configured to compare the one or more measured characteristics to one or more threshold characteristics, and to adjust one or more operating parameters of the system in response to a characteristic of the one or more measured characteristics falling outside a threshold of the one or more threshold characteristics.
Patent EP-4203349-A1 (EP)
Inventor: JIAO LIJUAN
IPC: H04L/
Filed: 2021-04-23
Abstract: This application provides a training method for a detection model, a system, a device, and a storage medium, belongs to the field of network security technologies, and further relates to application of an AI technology in the field of network security technologies. Some embodiments of this application provide a method for training a detection model by using federated learning. In the method, a gateway device serves as a participant of federated learning, and a server aggregates model parameters and delivers shared malicious samples for the gateway device. When the gateway device performs model training, the gateway device exchanges information such as the model parameters and the shared samples with the server, to obtain a detection model through training. The method helps alleviate a problem of insufficient malicious samples, and can drive training of a detection model by using richer malicious samples, thereby improving a model training effect.
Patent EP-4215299-A1 (EP)
Title: Alloy powder and preparation method therefor
Inventor: KIM BYUNGSUNG
IPC: B22F9/20
Filed: 2021-08-31
Abstract: An alloy powder preparation method according to an embodiment comprises the steps of: forming a mixture by mixing a plurality of metal compounds; and thermally treating the mixture, wherein, in the step of thermally treating the mixture, the process temperature changes according to the particle diameter of alloy powder. In addition, the step of thermally treating the mixture proceeds through hydrogen reduction at a process temperature of 300 to 700°C.
Patent EP-4214676-A1 (EP)
Inventor: COHEN AVRUM
IPC: G06T7/11
Filed: 2021-09-14
Abstract: Sont divulgués ici un procédé et un système de fonctionnement d'un système de microscopie. Une première image d'un échantillon acquis au moyen d'une première configuration d'imagerie est reçue. Une seconde image est développée à partir de la première image, la seconde image étant associée à une seconde configuration d'imagerie. Une séquence d'étapes de traitement d'image est appliquée à la première image afin de développer une première classification de premiers objets représentés dans la première image ainsi qu'à la seconde image afin de développer une seconde classification de seconds objets représentés dans la seconde image. Un score associé à la seconde configuration d'imagerie est développé qui représente une différence entre la première et la seconde classification. Les exigences de temps d'acquisition d'image ou de composant du fonctionnement du système de microscopie sont moins élevées lors d'un fonctionnement au moyen de la seconde configuration d'imagerie que lors d'un fonctionnement au moyen de la première configuration d'imagerie.
Patent EP-4221997-A1 (EP)
Inventor: GROSSMAN DANNY
IPC: B60C11/24
Filed: 2021-09-12
Abstract: L'invention concerne un procédé et un système d'estimation de la profondeur de la bande de roulement d'un pneu, le procédé consistant : à obtenir une image du pneu révélatrice de la bande de roulement et des rainures incorporées à l'intérieur de cette dernière, l'image étant acquise par un dispositif d'imagerie à partir d'un premier angle par rapport à une direction horizontale perpendiculaire à la surface de la bande de roulement, et le pneu étant éclairé par un dispositif d'éclairage à partir d'un second angle par rapport à la direction horizontale, ce qui provoque une section d'ombre et une section éclairée au niveau du fond et/ou de la paroi latérale d'une rainure, le premier angle étant inférieur au second angle, de telle sorte que l'image capture la section éclairée et au moins une partie de la section d'ombre ; à réaliser une segmentation sur l'image pour obtenir des segments d'image correspondant à la section éclairée et à ladite partie de la section d'ombre ; et à estimer la profondeur de la bande de roulement sur la base des segments d'image, de la largeur de rainure et du second angle.
Patent EP-4042677-A1 (EP)
Inventor: JIANG WEI
IPC: H04N19/00
Filed: 2021-06-15
Abstract: La présente invention concerne un procédé, un programme informatique, et un système informatique destinés à coder et décoder des données vidéo. Des données vidéo dans une première résolution et une qualité des données vidéo sont reçues. Un ou plusieurs premiers coefficients de pondération de premières couches d'un réseau neuronal et un ou plusieurs masques binaires pour le ou les premiers coefficients de pondération sont générés. Un ou plusieurs seconds coefficients de pondération de secondes couches du réseau neuronal sont générés sur la base de la qualité reçue des données vidéo. Les données vidéo sont décodées dans une seconde résolution par la réalisation d'une convolution sur les données vidéo reçues dans la première résolution à l'aide du ou des premiers coefficients de pondération générés qui sont masqués par le ou les masques binaires générés et à l'aide du ou des seconds coefficients de pondération générés.
Patent EP-4224980-A1 (EP)
Inventor: ZHANG YIZHONG
IPC: H04W76/10
Filed: 2021-11-02
Abstract: This application discloses a method for establishing a connected state, a terminal, a core network function, and an access network device, belonging to the field of wireless communication technologies. A method for establishing a connected state performed by a first terminal includes: receiving first information sent by a second terminal, where the first information includes at least one of: a second identifier, and network access information; and sending first indication information to a network side, where the first indication information includes at least one of: the second identifier, and a first identifier. The second identifier is used for indicating, to the network side, that the second terminal enters a connected state, and the first identifier is used for indicating, to the network side, that the first terminal enters a connected state.
Patent EP-4252672-A1 (EP)
Inventor: MATSUMOTO TSUYOSHI
IPC: A61B8/14
Filed: 2021-11-17
Abstract: Provided are an information processing apparatus, an ultrasound diagnostic apparatus, an information processing method, and an information processing program capable of presenting information indicating an appropriate degree of difficulty of a puncture according to a user who performs the puncture of a blood vessel. A body part 12 includes an acquisition unit 34 that acquires an ultrasound image U of a tissue including a blood vessel B of a subject, a detection unit 36 that detects the blood vessel B from the acquired ultrasound image U, and a degree-of-difficulty information output unit 44 that outputs degree-of-difficulty information related to a degree of difficulty of a puncture in the detected blood vessel B according to a skill level of a user who performs the puncture.
Patent EP-4224629-A1 (EP)
Title: Electronic apparatus comprising antenna and printed circuit board
Inventor: LEE HYUNGJOO
IPC: H01Q1/24
Filed: 2021-12-03
Abstract: An electronic device of various embodiments of the present disclosure may include: a display, a side bezel including at least one conductive portion, and a printed circuit board disposed inside the side bezel. The printed circuit board may include an interposer, and a first printed circuit board and a second printed circuit board electrically connected through the interposer. The first printed circuit board may include a first fill-cut area, and the second printed circuit board may include a second fill-cut area corresponding to the first fill-cut area, and a ground or feeding unit comprising a conductive feed of an antenna using the conductive portion may be disposed in the first fill-cut area or the second fill-cut area.
Patent EP-4250425-A1 (EP)
Inventor: MA QIANG
IPC: H01M10/0569
Filed: 2021-12-15
Abstract: This application provides a battery electrolytic solution, including an electrolyte salt and a non-aqueous organic solvent. The non-aqueous organic solvent includes a first organic solvent shown in a formula (I) and/or a second organic solvent shown in a formula (II): R 1 -S(=O) x -N(-R 3 )-R 2  formula (I); and R 1 -S(=O) x -N(-R 3 )-S(=O) y -R 4  formula (II). R 1  and R 4  are separately selected from fluoroalkyl, fluoroalkoxy, fluoroalkenyl, fluoroalkenyloxy, fluoroaryl, or fluoroaryloxy. R 2  and R 3  are separately selected from alkyl, alkoxy, alkenyl, alkenyloxy, aryl, or aryloxy. x is 1 or 2, and y is 1 or 2. A total content in mass of the first organic solvent and/or the second organic solvent in the electrolytic solution ranges from 10% to 90%. The electrolytic solution includes the first organic solvent and/or the second organic solvent of a high content in mass, so that side reactions between the electrolytic solution and the negative electrode can be reduced, thereby improving coulombic efficiency and cycling performance of the battery.
Patent EP-4262805-A1 (EP)
Inventor: BOTTONE CORY
IPC: A61K31/517
Filed: 2021-12-14
Abstract: La présente invention concerne des formes posologiques orales comprenant du létermovir et, en particulier, des mini-comprimés comprenant du létermovir. L'invention concerne également des procédés d'utilisation des formes posologiques orales pour le traitement, la prévention ou la prophylaxie du CMVH chez un patient. De plus, l'invention concerne également des procédés de fabrication des mini-comprimés de l'invention.
Patent EP-4264852-A1 (EP)
Inventor: KADOUS TAMER ADEL
IPC: H04B7/06
Filed: 2021-12-14
Abstract: Des aspects de la présente divulgation concernent des communications sans fil qui impliquent un faisceau quasi-omnidirectionnel et un faisceau directionnel, les communications sans fil impliquant des signaux radiofréquence ayant une fréquence relativement élevée (par exemple une fréquence supérieure à 20 GHz). Dans des modes de réalisation, un faisceau quasi-omnidirectionnel est émis sans fil, un faisceau directionnel est sélectionné sur la base du faisceau quasi-omnidirectionnel et une émission de données est reçue sur le faisceau directionnel sélectionné.
Patent EP-4273159-A1 (EP)
Inventor: XU TING
IPC: C07K14/605
Filed: 2021-12-27
Abstract: Provided in the present application is a human GLP-1 polypeptide variant, and a fusion protein or an immunoconjugate constructed by means of using the human GLP-1 polypeptide variant can be used for preventing and/or treating metabolic diseases or conditions related to GLP-1.
Patent EP-4271081-A1 (EP)
Inventor: KISHIDA AKIRA
IPC: H04W72/04
Filed: 2021-03-24
Abstract: A transmitting station (TX) according to an embodiment includes first and second wireless signal processing units (STA1 and STA2) and a link management unit (LM). The first and second wireless signal processing units are configured to be able to transmit wireless signals using first and second channels, respectively. The link management unit establishes multi-link with a receiving station by using the first and second wireless signal processing units. The link management unit is configured to be able to manage communication in which the multi-link are used and store first information (TBM) indicating a sequence number of transmission target data. When second information (RBM) indicating the sequence number of the data received by the receiving station is received from the receiving station via the first or second wireless signal processing unit, the link management unit sets a bit corresponding to the sequence number indicated by the second information in the first information as a transmitted bit.
Patent EP-4271341-A1 (EP)
Title: Pantiless liner
Inventor: TARA HARRIS
IPC: A61F13/53
Filed: 2021-12-29
Abstract: The invention relates to panty liners, and more particularly to a pantiless liner that has adhesive on the upper side. This pantiless liner helps to keep women dry and gives protection while maintaining a sleek look in your clothing. The pantiless liner having silicone or adhesive tape that will stick all day to the inner thigh around the vaginal wall without becoming unglued with sweat, moisture or any type of wetness. The adhesive tape may also reattach and hold if undone to use the restroom. A liner made in a regular design and size of a thong or similar to cover the vaginal area.
Patent EP-4221525-A1 (EP)
Inventor: KIM YONG HWAN
IPC: A24F40/50
Filed: 2021-12-28
Abstract: An aerosol generating apparatus includes: a heater configured to heat an aerosol generating substrate; a puff sensor configured to measure an amount of a user's puff; and a controller configured to determine a vaporization amount of the aerosol generating substrate, based on a puff sensing value indicating the amount of the user's puff, and control a heating time of the heater, based on the determined vaporization amount.
Patent EP-4278677-A1 (EP)
Inventor: YAN LE
IPC: H04W36/00
Filed: 2021-01-14
Abstract: The present application relates to a method and an apparatus for performing a Primary Secondary Cell (PSCell) change procedure. One embodiment of the present disclosure provides a method, which includes: receiving first information associated with a user equipment (UE) for a secondary node (SN) change or a primary secondary cell (PSCell) change; and/or receiving second information associated with one or more candidate nodes for the SN change or the PSCell change; and determining an action regarding the SN change or the PSCell change with a machine learning (ML) model based on the first information and/or the second information.
Patent EP-4279573-A1 (EP)
Title: Device, kit and method for extracting nucleic acids
Inventor: ZHAN WEI
IPC: C12M1/00
Filed: 2021-06-03
Abstract: The present invention provides a device, kit and method for extracting and testing nucleic acids. The devices comprises: a first container (101), a second container (102), and an air storage device (103), wherein the first container (101) is used for accommodating or containing a reagent for extracting nucleic acids; a first valve (107) is provided between the first container (101) and the second container (102); the second container (102) and the gas storage device (103) are in fluid communication; the second container (102) has a sample inlet (104) and a sample outlet (105), and the sample inlet (104) is provided with a fourth valve (109); the sample outlet device, a waste liquid pool, a collecting pool and the like. The method comprises: adding a nucleic acid sample, adsorbing nucleic acids by using magnetic beads, driving a nucleic extraction reagent, splitting, washing and eluting the nucleic acid sample, and extract nucleic acids, and significantly reduce the possibility of contamination occurring during nucleic acid extraction.
Patent EP-4282562-A1 (EP)
Inventor: OGURI SHOICHIRO
IPC: B23B19/02
Filed: 2021-12-23
Abstract: Provided are a bearing device and a main spindle device for a machine tool capable of achieving both high load capacity and high speed rotation. The bearing device has a plurality of angular contact ball bearings (41, 42, 43, 44) arranged in a back-to-back combination in an axial direction, and receives a load from one side thereof in the axial direction. Ball diameters (Da41, Da42) of the angular contact ball bearings on a load side (41, 42) are larger than ball diameters (Da43, Da44) of the angular contact ball bearings on an anti-load side (43, 44).
Patent EP-4245194-A1 (EP)
Title: Steam generator control method and device, steam generator and steam oven
Inventor: MAI ZHIWEN
IPC: A47J27/04
Filed: 2021-10-28
Abstract: Some embodiments of the present invention provideThe present disclosure provides a method and apparatus for controlling a steam generator, a steam generator and a steam oven. The method for controlling a steam generator includes: acquiring a target operating temperature of the steam generator; acquiring a current operating temperature of the steam generator according to a preset time period; determining an operating duration of the water pump in a next preset time period according to a relationship between the current operating temperature and the target operating temperature; and controlling the water pump to supplement water for the steam generator based on the operating duration in the next preset time period, and thus by periodically detecting the current operating temperature of the steam generator, and adjusting the operating duration of the water pump in a next period according to a relationship between the current operating temperature and the target operating temperature, the water supplementing amount is adjusted by means of such a periodic control manner, and more accurate water supplementing is provided for the steam generator, avoiding the problems that inlet water cannot evaporate in time due to an excessive water supplementing amount at one time and an outlet of the steam generator sprays water, which continuously provides users with steam satisfying use requirements, thereby improving the use experience of the users.