baber/WOPTO huggingface dataset:
Patent EA-004474-B1 (EA)
Title: Combined treating of cns diseases, especially parkinson's disease by combined administration of cabergoline and pramipexole
Inventor: GOMEZ-MANCILLA BALTAZAR
IPC: A61K31/44
Filed: 1999-05-07
Abstract: 1. A method of treating patients suffering from CNS disease comprising the administration to the patent of both cabergoline and pramipexole or their pharmacologically acceptable salts. 2. A method of claim 1 for the treatment of patients suffering from Parkinson's Disease. 3. A method of claim 2 where the initial dose of cabergoline is administered to the patient at a dose of 0.5 to 1 mg/patient/day and is adjusted upward at weekly intervals to a therapeutic dosage of 2,4,6,8 or 10 mg/patient/day and where the initial dose of pramipexole is started at 0.375 mg/patient/day and is adjusted upward every 5 to 7 days to a therapeutic dosage of 3,4,5,6,or 7 mg/patient/day. 4. The method of claim 3 where the cabergoline is administered to the patient at a dose of 0.5 to 1 mg/patient/day and is adjusted upward at weekly intervals to a therapeutic dosage of 4, or 6 mg/patient/day and the pramipexole is adjusted upward weekly to a dosage of 5 or 6 mg/patient/day. 5. The method of claim 4 where the therapeutic dose of cabergoline is 6 mg/patient/day and the therapeutic dose of pramipexole s 5 mg/patient/day. 6. Use of cabergoline in combination with pramipexole or their pharmacologically acceptable salts as a medicament for use in treating Parkinson's Disease (PD). 7. A pharmaceutical composition for treatment of Parkinson's Disease (PD), comprising cabergoline in combination with pramipexole or their pharmacologically acceptable salts or pharmacologically acceptable carrier.
Patent EA-010694-B1 (EA)
Title: Process based on the use of zeolites for the treatment of contaminated water
Inventor: VIGNOLA RODOLFO
IPC: C02F1/28
Filed: 2002-06-12
Abstract: A process is described for the treatment of water contaminated by apolar compounds consisting of halogenated solvents, aliphatic compounds, aromatic compounds or their mixtures which consists in treating the water with one or more apolar zeolites characterized by a silica/alumina ratio > 50 and by the presence of structural channels having dimensions similar to those of the molecules of the contaminating compounds.
Patent EA-012085-B1 (EA)
Title: Photo-catalytic reactor
Inventor: MACPHEE DONALD ELLIOT
IPC: H01M8/06
Filed: 2004-02-27
Abstract: A photocatalytic reactor, capable of generating an electric current by consumption of a fuel containing organic material, comprises a direct oxidation fuel cell including an anode and a cathode, wherein the anode is a photocatalysis-assisted anode which comprises a photocatalyst on a surface of an electrically-conductive substrate so arranged as to be receptive to light, and a light-transmissive proton-conductive membrane arranged between said anode and the cathode, such that light passes through said membrane as a final stage in the optical path to the photocatalyst, the said photocatalyst being capable of promoting the oxidation of organic material and generating electron-hole pairs, said reactor being configured to support multiple cells in a stacked array, is provided with means for introducing said fuel and means for connection to an external electrical circuit.
Patent EA-013214-B1 (EA)
Title: Use a pharmaceutical composition for the treatment of diabetes, metabolic syndrome, neuro-degenerative diseases and obesity
Inventor: YOO SANG-KU
IPC: A61P3/10
Filed: 2006-02-15
Abstract: The present invention relates to use of a pharmaceutical composition in the preparation of a drug for the treatment or prevention of a disease syndrome, comprising: a therapeutically effective amount of a compound represented by Formula Ior and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof, wherein the disease syndrome is obesity, an obesity complication, a liver disease, arteriosclerosis, cerebral apoplexy, myocardial infarction, a cardiovascular disease, an ischemic disease, diabetes, a diabetes-related complication or an inflammatory disease.
Patent EA-013419-B1 (EA)
Title: Method and system for controlling a down hole flow control device
Inventor: VACHON GUY P
IPC: E21B34/16
Filed: 2007-02-12
Abstract: A system for controlling flow in a wellbore uses a downhole flow control device positioned at a downhole location in the wellbore. The flow control device has a movable element for controlling a downhole fluid flow. In response to an applied pressure pulse, the movable element moves in finite increments from one position to another. In one embodiment, a hydraulic source generates a transmitted pressure pulse to the flow control device wherein the maximum pressure of a received pressure pulse downhole is sufficient to overcome a static friction force associated with the movable element, and wherein a minimum pressure of the received pressure pulse downhole is insufficient to overcome a dynamic friction force associated with the movable element.
Patent EA-022197-B1 (EA)
Title: Composition for biological pest control on plants, use thereof, a container for rearing a phytoseiid predatory mite, and methods for rearing a phytoseiid predatory mite and for biological pest control on a crop
Inventor: BOLCKMANS KAREL JOZEF FLORENT
IPC: A01K67/00
Filed: 2005-12-29
Abstract: The present invention relates to a novel biological pest control composition in plants, mites, comprising a population of a phytoseiid predatory mite species selected from the subfamily of the Amblyseiinae, the subfamily of Typhlodrominae, and a factitious host population comprising a species selected from the Glycyphagidae, a food substance suitable for said factitious host population and a carrier for said factitious host population, used in a container for rearing a phytoseiid predatory mite, and to a method for rearing said phytoseiid predatory mite and to a method for biological pest control in a crop using said composition.
Patent EA-015657-B1 (EA)
Title: Rage fusion proteins and methods of use
Inventor: MJALLI ADNAN M M
IPC: C07K14/705
Filed: 2007-01-23
Abstract: Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to an immunoglobulin CH2 domain. Such fusion proteins may provide specific, high affinity binding to RAGE ligands. Also disclosed is the use of the RAGE fusion proteins as therapeutics for RAGE-mediated pathologies.
Patent EA-018229-B1 (EA)
Title: Crystalline solvates and complexes of (1s)-1,5-anhydro-1-c-(3-((phenyl)methyl)phenyl)-d-glucitol derivatives with amino acids as sglt2 inhibitors for the treatment of diabetes
Inventor: GOUGOUTAS JACK Z
IPC: A61K31/70
Filed: 2007-06-21
Abstract: The present invention relates to physical crystal structures of a compound of the formulae Ia and If and to pharmaceutical compositions containing said structure of a compound Ia.
Patent EA-014855-B1 (EA)
Title: Mono-and divalent salts of n-(5-hydroxynicotinoil)-l-glutaminic acid exhibiting psychotropic (antidepressant and anxyolytic), neuroprotective, heroprotective and cerebroprotective action
Inventor: YAKIMUK PAVEL VASILYEVICH
IPC: A61K31/195
Filed: 2007-06-06
Abstract: The invention relates to medicine, in particular to mono-and divalent salts of N-(5-hydroxynicotinoil)-L-glutaminic acid exhibiting psychotropic antidepressant, anxyolytic, heroprotective, neuroprotective, antihypoxia cerebroprotective and nootropic action. The novel compounds differ from the known preparations, including the closest prior art in the form of a N-(5-hydroxynicotinoil)-L-glutaminic acid base (nooglucotyl), in that they produce psychotropic effects, namely antidepressant, anxyolytic, neuroprotective and heroprotective actions, in such a way that lesion focuses caused by apoplectic attacks are reduced and age-specific neurological deficiencies and intellectual and physical work capacities are improved.
Patent EA-016251-B1 (EA)
Title: 8-PIPERIDINYL-2-PYRIDINYL-PYRIMIDO [1,2-a] PIRIMIDIN-4-ONE DERIVATIVES
Inventor: LOCHED ALISTAIR
IPC: A61K31/519
Filed: 2007-11-06
Abstract: The invention relates to a pyrimidone derivative represented by formula (I) or a salt thereofwherein: Y represents a bond, a carbonyl group; R1 represents a 2, 3 or 4-pyridinyl; R2 represents an optionally substituted a benzene ring; R4 represents a hydrogen atom, a Calkoxy carbonyl group or a Calkyl group; n represents 0 to 3. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
Patent EA-020012-B1 (EA)
Title: A system and method for remotely controlling the movement of a series of connected vehicles
Inventor: EVANS JAY
IPC: B61L3/12
Filed: 2009-05-21
Abstract: A remote control system for controlling movement of a train comprises one or more sensors positioned relative to a railroad track for detecting the presence of a lead railcar on the track being pushed by a remotely controllable locomotive. The one or more sensors are spaced a distance from a predetermined stop location of a lead railcar and transmit signals when the lead railcar is detected on the track. A programmable controller positioned off-board or wayside receives signals from the one or more sensors and is in radio communication with an onboard operating system of the locomotive. The controller transmits a signal to the locomotive when the lead railcar is detected by a sensor, and in response to the signal the operating system of the locomotive sets a maximum speed setting for the locomotive to travel on the track toward the stop location.
Patent EA-022750-B1 (EA)
Title: Bicycling exercise apparatus
Inventor: IRVING COLIN
IPC: A63B69/16
Filed: 2007-12-06
Abstract: An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame and a first mounting point and a second mounting point configured to maintain the frame. A seat is connected to the frame and configured to support the user. A wheel is positioned in association with said frame and pedals configured to interact with the wheel, and the frame is configured to pivot about the first mounting point and second mounting point in response to leaning by the user. Handlebars may be provided that enable further force application and enhance the leaning or pivoting in the bicycle riding simulation experience.
Patent EA-020313-B1 (EA)
Title: Process for ethylbenzene production
Inventor: BUTLER JAMES R
IPC: C07C2/00
Filed: 2009-09-29
Abstract: A method of producing an alkylaromatic by the alkylation of an aromatic with an alkylating agent, such as producing ethylbenzene by an alkylation reaction of benzene, is disclosed. The method includes using an H-beta catalyst to minimize process upsets due to alkylation catalyst deactivation and the resulting catalyst regeneration or replacement. The H-beta catalyst can be used in a preliminary alkylation reactor that is located upstream of the primary alkylation reactor. The H-beta catalyst used in a preliminary alkylation reactor can reduce the deactivation of the catalyst in the primary alkylation reactor.
Patent EA-020962-B1 (EA)
Title: Compounds and compositions as tlr activity modulators
Inventor: CORTEZ ALEX
IPC: C07D471/04
Filed: 2010-09-01
Abstract: The invention provides a novel class of compounds of formula (I), immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect of the invention, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.
Patent EA-026067-B1 (EA)
Title: Conversion of carbon containing feedstock
Inventor: KAUCHALI SHEHZAAD
IPC: C10G2/00
Filed: 2010-10-28
Abstract: The present invention relates to a process for the conversion of carbon containing feedstock to a liquid chemical product, particularly a liquid fuel product, wherein carbon dioxide emissions are minimized.
Patent EA-023448-B1 (EA)
Title: Apparatus for cutting a large and super-large tyre
Inventor: FILIPPOV EVGENII DMITRIEVICH
IPC: B26D7/01
Filed: 2012-04-04
Abstract: The invention relates to mechanical engineering, and specifically to equipment used for reclaiming car tyres (worn and defective tyres, etc.), and can be used in an apparatus cutting a large and a particularly large tyre, which has a diameter of up to 4.1 m and is either diagonal with a textile cord or is radial with a metal cord, into segments of a required size for further processing. An apparatus for cutting a large or super-large tyre is claimed, the apparatus comprising a frame with a platform, on which the tyre is placed, a tyre clamp, and also a lower and an upper cutting knife, and an actuator. The novelty consists in that the knives are L-shaped and are mounted on two L-shaped bases which are movably fixed to each other and form power cutters which can be set into motion by the actuator and which are hinged on the frame, wherein the platform on which the tyre is placed is equipped with the tyre clamp and is provided with a lifting and/or inclining and/or rotating mechanism, and also with a mechanism for linear displacement of the platform along the frame.
Patent EA-027741-B1 (EA)
Title: Method and additives for increasing starting resistance
Inventor: BULLERJAHN FRANK
IPC: C04B40/00
Filed: 2012-07-16
Abstract: The present invention relates to a method for accelerating the hardening of hydraulic or latent-hydraulic binding agents, wherein ternesite and an aluminium component are added to the binding agents, and also to an additive which increases the starting resistance of hydraulic or latent hydraulic binding agents, containing ternesite and a non-hydraulically reactive aluminium component, and further to the use of an additive comprising ternesite and an aluminium component for accelerating the hardening of hydraulic or latent hydraulic binding agents.
Patent EA-035114-B1 (EA)
Title: Neural network and method of neural network training
Inventor: PESCIANSCHI DMITRI VILENOVICH
IPC: G06E1/00
Filed: 2015-03-06
Abstract: The invention relates to an artificial neural network and a method of training the same. The neural network includes a plurality of inputs for receiving input signals, and synapses connected to the inputs and having corrective weights. The network additionally includes distributors. Each distributor is connected to one of the inputs for receiving the respective input signal and selects one or more corrective weights in correlation with the input value. The network also includes neurons. Each neuron has an output connected with at least one of the inputs via one synapse and generates a neuron sum by summing corrective weights selected from each synapse connected to the respective neuron. Furthermore, the network includes a weight correction calculator that receives a desired output signal, determines a deviation of the neuron sum from the desired output signal value, and modifies respective corrective weights using the determined deviation. Adding up the modified corrective weights to determine the neuron sum minimizes the subject deviation for training the neural network. The technical result consists in shortening training time and reducing computational resources required for training neural networks.
Patent EA-035413-B1 (EA)
Title: Cell populations, methods of transdifferention and methods of use thereof
Inventor: FERBER SARAH
IPC: A61K35/12
Filed: 2014-06-13
Abstract: The present invention provides methods for the sequential and temporally-regulated administration of pancreatic transcription factors to induce non-pancreatic cells to transdifferentiate and mature along the pancreatic -cell lineage. The present invention also provides methods for identifying, isolating and enriching transdifferentiation predisposed cells and methods for treating a degenerative pancreatic disorder such as diabetes.
Patent EA-035263-B1 (EA)
Title: Connector for pipes
Inventor: HEATON ANDREW JAMES
IPC: F16L21/06
Filed: 2015-09-29
Abstract: A pipe connector for connecting pipes that includes an elongate tubular body having an outer diameter, a sleeve disposed over the elongate tubular body, and a first wire ring. The elongate tubular body that has a groove formed on the outer diameter. The sleeve has a groove formed on an inner diameter that is spaced from a first end of the sleeve and is aligned with the groove of the elongate tubular member. The first wire ring is disposed within the groove of the elongate tubular body and within the groove of the sleeve such that the sleeve is coupled to the elongate tubular body by the first wire ring.
Patent EA-037440-B1 (EA)
Title: Conveying apparatus
Inventor: MADER LEOPOLD
IPC: B23Q41/02
Filed: 2017-06-26
Abstract: An apparatus (1) for conveying glass panels (2, 3) contains a conveying device comprising a feed conveyor (4) and a removal conveyor (6), and also a region (5) with a processing station. A lifting device (10) for glass panels is provided upstream of the processing station and a lowering device (16) for glass panels is provided downstream of the processing station, wherein a linear-conveying device (11) is provided between the lifting device (10) and the lowering device (16). It is thus possible for glass panels (3) to be moved, by raising action (arrow 13), linear movement (arrow 17) and lowering action (arrow 14), around a first component located in the region (5) in the processing station, the second component therefore passing the first component. During the passing operation, the second component always remains in the conveying plane, which is the same as the plane of the second component.
Patent EA-037413-B1 (EA)
Title: Method for sclerotherapy of varicose veins of lower extremities
Inventor: BURUMKULOV ERIK RAKISHEVICH
IPC: A61K9/00
Filed: 2019-05-16
Abstract: The invention relates to medicine, in particular to vascular surgery, and can be used for sclerotherapy of varicose veins of the lower extremities, with congenital vascular malformations, with arteriovenous fistulas, with chronic venous insufficiency (CVI) according to CEAP C1-C6, and other diseases of the vascular system. The technical result from the use of the proposed invention is to increase the effectiveness of sclerotherapy of varicose veins by eliminating the local-traumatic effect on the inner shell of the venous wall and shortening the periods of formation of the connective tissue bundle. As a sclerosing drug, a platelet-rich autologous plasmagel produced by the Plasmolifting technology from a patient blood is used; the preliminary injection points are marked on the patient varicose vein, with patient in a horizontal position, with a 21G-27G needle or with the help of an appropriate cannula into the lumen of the vessel slowly under visual or ultrasound control, 0.3-0.7 ml of plasmagel injected preheated in a thermostat to a temperature of 65-85 °C for 6 minutes. After the first injection, with sequentially moving in the proximal direction, the procedure is repeated at each of the distal target points. In doing so, the position of the tip of the needle in the vessel with each injection is identified by the appearance of dark blood in the syringe during back traction of the syringe plunger. If necessary, the additional extravasal injection of 0.3-0.7 ml of plasmogel is carried out at each proximal point of the proposed border of vessel obliteration, after which compression bandage of adhesive bands is applied to varicose veins or compression stockings of the 2nd class is used.
Patent ES-2177398-B1 (ES)
Title: Mejoras introducidas en la patente de invencion n- p-200000503/p por: forjado unidireccional, con paneles prefabricados de hormigon armado, y molde para fabricacion de los paneles.
Inventor: FERNANDEZ FERNANDEZ JAVIER
IPC: E04B5/06
Filed: 2000-06-15
Granted: 2004-09-01
Abstract: Mejoras introducidas en la patente de inveción nº P200000503/9 por: forjado unidireccional con paneles prefabricados de hormigón armado, y molde para fabricación de los paneles. El forjado unidireccional es del tipo construido mediante paneles tubulares (7, 20) de hormigón con armaduras (13, 16) y con núcleo (8,18) de poliestireno expandido, adosándose los paneles coplanariamente y efectuando ulteriormente un vertido de hormigón para unión y sellado de los mismos. La forma geométrica de su sección es en general trapecial con ángulos interiores truncados, o bien, con los lados menores compuestos por diferentes tramos de distintas angulaciones. Los paneles (20) incorporan uno o más nervios longitudinales centrales (17) de refuerzo, con los núcleos de poliestireno (18) colaterales a ellos. La parte superior de los paneles, (7, 20) posee varillas transversales (14) sobresalientes para dar continuidad al forjado al verter el hormigón de relleno entre las viguetas o paneles. El molde (23) incorpora orificios superiores (31) para paso de dichas varillas transversales (14), quedando dispuestos sobre un bastidor de apoyo (34) separado con amortiguadores (33) para obtener vibración en la parte superior del molde (23).
Patent ES-2188403-B1 (ES)
Inventor: PISERRA SANCHEZ ERNESTO
IPC: A43B5/04
Filed: 2001-10-17
Granted: 2004-11-16
Abstract: This binding comprises two plates (1) fixed onto the snowboard (2), each of the plates (1) having protuberances (11) for slotting tightly into hollow parts (31), integral to the boot soles (3), the protuberances (11) of the plates (1) and the hollow parts (31) of the boots having lateral orifices (12 and 32) for the assembling of safety clips (13) for holding the boots (3) in the assembly position on the snowboard (2). <IMAGE>
Patent ES-2204268-B1 (ES)
Title: Estructura de montaje en deposito para bomba de combustible.
Inventor: OOTAKA TOSHIHIRO
IPC: B62J35/00
Filed: 2002-01-18
Granted: 2005-06-01
Abstract: Estructura de montaje en depósito para bomba de combustible. Objeto: Proporcionar una estructura de montaje para una bomba de combustible en lugar de un encaje por salto o conexión de bayoneta. Medios de solución: Se fija una tuerca 50 sobre un perno 31, por lo que una segunda porción de valle 41 se pone en contacto estrecho con una primera porción de montaje 33, como se representa. Entonces, una junta estanca 35 es aplastada apropiadamente por un aro de presión 40 mediante una porción de pestaña 21, de manera que se puede realizar suficientemente un efecto de sellado de la junta estanca 35. Efectos: No hay peligro de que se ejerza una fuerza de compresión superior a un cierto nivel en la porción de pestaña, de manera que se puede evitar la generación de fluencia incluso cuando la porción de pestaña se hace de una resina.
Patent ES-2193876-B1 (ES)
Title: Sistema de pintado para pasos de cebra y similares.
Inventor: AGUADO LOPEZ JUAN ANTONIO
IPC: E01F9/518
Filed: 2001-09-28
Granted: 2005-05-01
Abstract: Sistema de pintado para pasos de cebra y similares. Comprende las etapas de: - Mezclado de resinas de metacrilato con cargas antideslizantes y bióxido de titanio, utilizando peróxidos orgánicos como reticulantes de las resinas. - Colocación de un molde en forma de placa perforada flexible sobre la franja (2) a realizar. - Rellenado de los orificios del molde con la mezcla previamente preparada, enrasándolos hasta la cara superior de la placa que constituye el molde. - Retirada del molde, una vez endurecida la mezcla para dejar al descubierto los resaltes circulares (3) formados. - Opcionalmente, acabado final con una capa de pintura.