baber/WOPTO huggingface dataset:
Patent EP-0650354-B1 (EP)
Inventor: WUNDERLICH JENS-CHRISTIAN
IPC: A61K9/16
Filed: 1993-07-05
Granted: 1999-12-15
Abstract: PCT No. PCT/DE93/00592 Sec. 371 Date Mar. 17, 1995 Sec. 102(e) Date Mar. 17, 1995 PCT Filed Jul. 5, 1993 PCT Pub. No. WO94/01090 PCT Pub. Date Jan. 20, 1994Sparingly water-soluble active compounds, for example medicinal substances, are converted into the dissolved (molecularly disperse) state by dissolving them in a hydrophilic peptide having a molecular weight above 100 D, for example gelatin. The solubility both during storage and during use of the formulation by the user or patient is thereby ensured, without organic solvents or solubilizing agents which cause undesirable side effects being required.
Patent EP-0649423-B1 (EP)
Inventor: DYSON NORMAN H
IPC: C07D521/00
Filed: 1993-06-17
Granted: 1996-10-09
Abstract: This invention provides an improved process for the preparation of compounds of formula (I):    <IMAGE>  (I)  wherein: n is 0, 1 or 2; each R1 is independently halo or lower alkyl; R2 is nitro or -N(R3)R4 where R3 is hydrogen or lower alkyl; R4 is hydrogen, lower alkyl, lower alkylsulfonyl or -C(Y)R5 where Y is oxygen or sulfur and R5 is hydrogen, lower alkyl, lower alkoxy or -N(R6)R7 where R6 is hydrogen or lower alkyl and R7 is hydrogen, lower alkyl or lower alkoxycarbonyl; or R3 and R4 together with N is pyrrolidino, piperidino, morpholino, thiomorpholino or piperazino, wherein the piperazino is optionally substituted at the 4-position by -C(O)R8 where R8 is hydrogen, lower alkyl, lower alkoxy or amino; or pharmaceutically acceptable salts thereof. These compounds are useful in treating disease-states characterized by hypercholesterolemia.
Patent EP-0657023-B1 (EP)
Inventor: SPECKBROCK GERD
IPC: G01K5/22
Filed: 1993-08-16
Granted: 1996-06-26
Abstract: A clinical thermometer with maximum function with a non-toxic eutectic Ga alloy as measuring fluid 14 inside a measuring tube 13 which provides adhesion forces larger than the cohesion forces inherent in liquid 14. To reach the maximum function, therefore, the customary Hick'sche constriction is not required any more facilitating production and handling of said clinical thermometer. Furthermore, a special Ga/In/Sn alloy is described, which may be used not only for clinical thermometers but also as a lubricant.
Patent EP-0714342-B1 (EP)
Inventor: VIRSIK MILAN
IPC: B26D3/02
Filed: 1993-08-20
Granted: 2000-04-19
Abstract: A method of severing an elongated flat metal tube (10) of the type including upper and lower flat horizontal walls (10a, 10b), vertical edge walls and vertical partition walls spaced between the edge walls and interconnecting the upper and lower walls to divide the tube into a series of parallel, generally rectangular, longitudinally extending passages. The tube is cut by forming transverse kerfs in the upper and lower walls of the tube and thereafter exerting a relative pulling force on the tube sections on opposite sides of the plane in which the kerfs have been formed to tear apart the remaining tube material at the severing plane and sever the tube. The kerfs are formed in a two-step broaching operation comprising a first cut in which a narrow generally V-shaped narrow angle kerf is formed and a second cut in which the kerf is widened to provide a wide, generally V-shaped, wide angle kerf.
Patent EP-0660793-B1 (EP)
Title: Bouchon a fixation rapide pour reservoir de carburant
Inventor: GRIFFIN JEFFREY ROUTE
IPC: B65D51/00
Filed: 1993-09-21
Granted: 1997-12-29
Abstract: Un bouchon à fixation rapide (10) comporte une partie centrale (18) et une douille (14) mobile par rapport à cette dernière. La douille (14) porte une bague d'étanchéité (34) configurée pour assurer l'étanchéité par rapport à une tubulure de remplissage (22). Un mécanisme de serrage est accouplé à la partie centrale (18) et à la douille (14) et sert la tubulure de remplissage (22) pour comprimer la bague d'étanchéité (34) entre la douille (14) et la tubulure de remplissage (22) en réaction à un mouvement de la partie centrale (18) par rapport à la douille (14) dans un sens de montage du bouchon. La fermeture comporte également un couvercle de man÷uvre (12) accouplé à la partie centrale (18) pour permettre à un utilisateur de mettre en mouvement la partie centrale (18) par rapport à la douille (14) dans le sens de montage du bouchon, ce mouvement étant suffisant pour actionner le mécanisme de serrage. La douille (14) est traversée par un passage renfermant la partie centrale cylindrique (18). On fait tourner la partie centrale (18) d'une fraction de tour par rapport à la douille (14) pour actionner le mécanisme de serrage.
Patent EP-0665010-B1 (EP)
Inventor: NAKAMICHI KOUICHI
IPC: A61K47/44
Filed: 1993-10-14
Granted: 2002-09-11
Abstract: A method capable of manufacturing wax matrices efficiently in large quantities at once characterized in that a multiscrew extruder is used to achieve the object.
Patent EP-0611649-B1 (EP)
Inventor: HERTEL JAMES E
IPC: B41F31/02
Filed: 1994-01-12
Granted: 1997-11-05
Abstract: Apparatus and method for flexographic printing wherein a holder (24) equipped with upper and lower doctor blades (25,26) is installed in a generally C-shaped subframe (22) adjacent an anilox roll (21) in the press. <IMAGE>
Patent EP-0631775-B1 (EP)
Inventor: CONTE UBALDO
IPC: A61K9/22
Filed: 1994-05-20
Granted: 1999-08-18
Abstract: A pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times produced via the steps of: a) preparing a tablet consisting of three superposed layers, the upper layer containing an active ingredient, the intermediate layer not containing any active ingredient and forming a barrier-type layer, and the lower layer containing an active ingredient, said upper layer presenting a raised top, b) coating the tablet entirely with an impermeable polymeric film, and c) removing said raised top and thus allowing contact of the abraded upper layer surface with the environment. <IMAGE>
Patent EP-0631990-B1 (EP)
Inventor: SORG HELMUT DIPL-ING
IPC: C03B3/02
Filed: 1994-06-06
Granted: 1999-05-12
Abstract: A method and apparatus for preheating material in a glass melting furnace is provided. An indirect heat exchanger is utilized in which exhaust gases from the glass melting furnace are directed, in a counter flow relation, to raw materials and glass cullet being fed into a glass melting furnace. A first conduit is connected to the heat exchanger to withdraw gases formed from the decomposition of organic matter present in the materials being preheated and the gases are directed by the conduit into the glass melting furnace where they are combusted. A second conduit may also be provided for extracting water vapor released from the preheated materials prior to decomposition of the organic material.
Patent EP-0641040-B1 (EP)
Inventor: EMBO GEORGES IND-ING
IPC: H01R13/41
Filed: 1994-08-30
Granted: 2002-02-27
Abstract: In order to be able to push the female connector strip in by means of a flat stamp pressing against it from above, the fastening sections of the contact springs are guided in a clamping manner, parallel to the push-in parts (2), at least in certain areas between an inner insulating material body (4) and an outer insulation material body (6), and the contact springs are povided with in each case one recess (3) in the fastening section, into which recess (3) the inner insulating material body (4) engages, in each case by means of a tab (5), transversely with respect to the push-in parts (2). <IMAGE>
Patent EP-0694499-B1 (EP)
Inventor: BAUMANN GERD DIPL-ING
IPC: B67D7/40
Filed: 1994-08-31
Granted: 1996-02-21
Abstract: The retraction arrangement is fitted to a vehicle fuel-dispensing pump. The fuel dispensing hose (3) is loaded in the opening direction by a spring (6) in the housing (2). The spring makes contact with the hose via an outlier (7). The spring is fitted inside the housing and the outlier can be swivelled out of the housing through the opening (2b) provided for the removal of the hose. The free end of the outlier engages the hose via an oval-shaped opening (8) which acts as a hose guide. <IMAGE>
Patent EP-0648428-B1 (EP)
Inventor: COMELLI MAURIZIO
IPC: A23L3/06
Filed: 1994-09-29
Granted: 2000-03-29
Abstract: Spiral refrigerator tunnel for products that have just been coated with chocolate or substances of an analogous type, which is positioned downstream of a coating or pouring station (11), the refrigerator tunnel (17) comprising an endless belt (18) wound in a spiral with an outward segment and a return segment, the outward segment being higher and the return segment being lower, the outward and return segments being counterparts of each other, the outward segment acting to convey the products (12), refrigeration means, belt feeder means and means to feed (16) and to remove (21) the products (12) being included, the endless belt (18) being a belt having an endless smooth supporting surface without holes or openings and consisting of cloth or of a plastic or composite material, the endless belt (18) being produced by starting with a determined plurality of circular rings cut and joined together to form a double spiral having the same geometric parameters as the spiral of the tunnel (17), the endless belt (18) having its loading edge and delivery edge in a selected radial position defined at a desired position in its upper level and/or lower level coils. <IMAGE>
Patent EP-0635632-B1 (EP)
Inventor: TORKELSON DELBERT W
IPC: F02K1/38
Filed: 1994-06-16
Granted: 1997-10-22
Abstract: An internal flow mixer (12) is attached to the rearward end of a turbofan engine (10) for inverting the engine fan (22) and core streams (24). Rearwardly of the internal flow mixer (12) is a multi-lobed exhaust nozzle (14) which mixes ambient air with the gases flowing from the flow mixer (12). An ejector housing (16) lined with acoustic absorption material receives the flow from the exhaust nozzle (14) and discharges the thrust producing gases in noise abatement condition. <IMAGE>
Patent EP-0636685-B1 (EP)
Inventor: KOLAITIS LEONIDAS
IPC: C09K23/54
Filed: 1994-07-19
Granted: 1999-11-10
Abstract: A method of providing a foam control agent with 1 to 30 parts of a silicone antifoam and 70 to 99 parts of a zeolite carrier, with the ability to release some of the antifoam within 10 minutes of being dispersed in an aqueous surfactant solution, by depositing 5 to 70% of the antifoam of an organo-polysiloxane polyoxyalkylene copolymer, onto the zeolite carrier not later than depositing the silicone antifoam. Also claimed is the use of the copolymer to achieve that end and compositions where the antifoam is branched or high viscosity. Also claimed is encapsulated agents.
Patent EP-0667879-B1 (EP)
Inventor: GLAD GUNNAR
IPC: B08B17/06
Filed: 1993-11-05
Granted: 1999-06-16
Abstract: A method of modifying a polymer based surface by coating with particles comprises converting the top layer of the polymer based surface to a swollen or semidissolved state without the use of adhesive and simultaneously or subsequently contacting the polymer based surface with the particles.
Patent EP-0666985-B1 (EP)
Inventor: DAUGHERTY ANN L
IPC: G01N33/487
Filed: 1993-11-02
Granted: 1997-07-16
Abstract: A compaction assay measuring the viscoelasticity of sputum samples of patients subject to respiratory disease is provided. This assay is useful in determining the therapeutic efficacy of DNase, antibiotic and other respiratory disease treatments in improving lung function.
Patent EP-0633948-B1 (EP)
Inventor: NIXON RICHARD CHARLES CAMERON
IPC: C22C1/03
Filed: 1994-01-20
Granted: 1999-06-09
Abstract: An alloying additive of fine metallurgical structure is made by providing a melt of a suitable alloying material, for example an aluminium-based melt containing one or more alloying components for treating an aluminium-based melt for grain refinement, modification, conductivity reduction and/or addition of alloying metal, and applying one or more substantially unatomised streams of the melt to a cooling surface, e.g. the cylindrical exterior surface of a water-cooled rotating metal drum, to produce a splat product, which is then arranged into a dosage form suitable for making measured alloying additions, preferably having first been granulated.
Patent EP-0641770-B1 (EP)
Inventor: KATANO KIYOAKI
IPC: C07D401/06
Filed: 1994-03-17
Granted: 1998-05-13
Abstract: A compound with a platelet aggregation inhibitor activity, represented by the following general formula (I), and pharmacologically acceptable salt and solvate thereof. Examples of the compound are as in (II). <CHEM>
Patent EP-0724459-B1 (EP)
Inventor: YIM KALVIN W K
IPC: A61L27/00
Filed: 1994-09-02
Granted: 2003-05-02
Abstract: A composition is disclosed comprising a pharmaceutically acceptable admixture of an osteogenic protein; a porous particulate polymer matrix; an osteogenic protein-sequestering amount of blood clot; and a calcium sulfate hemihydrate-containing substance. Also disclosed are formulations of bone morphogenetic proteins with improved solubility and/or stability characteristics.
Patent EP-0668059-B1 (EP)
Inventor: TELLMAN LARS
IPC: A61B17/74
Filed: 1995-02-16
Granted: 2000-01-05
Abstract: The present invention relates to an implant for fixing femoral fractures and the like. The implant consists of three main parts, namely a first part consisting of an angle element (1), a second part which forms a holder (2) and a third part in the form of a screw (3). The angle element (1) includes a sleeve (10) for receiving the screw (3). Both the sleeve (10) and the screw (3) are intended to be passed into a channel provided through the neck and head of the femur of a patient. The angle element (1) moreover includes a slide (11) which is slidingly accommodated by the holder (2). The holder (2) is, in its turn, secured by means of anchorage screws (5) in the shaft of the femur. By cooperation between the slide (11) and the holder (2) the possibility is afforded that the angle element (1) may move in relation to the shaft of the femur. The sleeve (10) of the angle element (1) is disposed at an angle ( alpha ) in relation to the slide (11). <IMAGE>
Patent EP-0671151-B1 (EP)
Inventor: SCHAEFER BERND
IPC: A61B17/70
Filed: 1995-03-01
Granted: 2000-02-09
Abstract: A vertebra of a spinal column is fitted with two bone screws (5,6), each with a screw head to which is screwed a rod. Both rods are interconnected by a transverse coupler. Only one rod is of an active, variably adjustable type. The active rod is pref. threaded. It can have a row of teeth, bones, peripheral grooves etc. The transverse coupler may be in the form of a bone plate with several fastening bones for the two bone screws. Alternately the coupler may be a transverse rod.
Patent EP-0686821-B1 (EP)
Inventor: NIENABER BERND DIPL-ING
IPC: F27D15/02
Filed: 1995-04-13
Granted: 1998-09-16
Abstract: A double layered cooling bed is made up of a lower precooled lower layer (10) coated with an upper layer (11) of hot material. The layers are separated by a wall-like dam (18) made up of some of the material. The top layer passes to crusher rollers (16) while the bottom layer falls through shaft (15) onto table (20). The height of the dam (18) is controlled by the inclination of slide surface (17) which can be adjusted. <IMAGE>
Patent EP-0664945-B1 (EP)
Inventor: THORUD RICHARD A
IPC: A01D43/063
Filed: 1990-07-26
Granted: 1999-08-25
Abstract: A convertible mulching mower (10) including a housing (12) and chute (30). Chute (30) can be selectively blocked with a chute plug (32) to selectively put mower (10) in a mulching mode. Mounted beneath housing (12) is a plurality of kickers (72) which serve to deflect the grass clippings generally downwardly and inwardly to cause them to penetrate the standing grass blades in the cutting path, when the mower (10) is in its mulching mode (when chute plug (32) is blocking discharge chute (30)). When chute plug (32) is removed, it can be replaced by various grass handling means, including a grass bag or a side discharge chute extension. <IMAGE>   <IMAGE>   <IMAGE>
Patent EP-0689151-B1 (EP)
Inventor: PALMER JOHN P
IPC: H04L12/28
Filed: 1995-04-20
Granted: 2003-08-27
Abstract: A system and a method for storage and communication of information between at least one first information containing terminal (10) and a second terminal (12), are disclosed. A random number is generated (266) within the first terminal (10) in response to receipt of a begin signal from the second terminal (12), and the random number is compared with a count incremented and maintained by a digital counter (264) within the first terminal (10). When the random number is equal (70) to the count, the first terminal (10) transmits (72) a request-to-transmit signal (RTT) to the second terminal (12). If the second terminal (12) responds with a first acknowledgment, the first terminal (10) then sends (80) an information-containing signal to the second terminal (12). If the information-containing signal is correctly received, the second terminal (12) responds by transmitting a second acknowledgment which is received by the first terminal (10). The storage and communication of information method disclosed may be employed in a supermarket checkout system, with the first information-containing terminals (10) comprising RFID tags. <IMAGE>   <IMAGE>   <IMAGE>
Patent EP-0717105-B1 (EP)
Inventor: CHANGEUX JEAN-PIERRE
IPC: C07H21/04
Filed: 1995-12-14
Granted: 2005-02-23
Abstract: Several genes encoding subunits of the neuronal nicotinic acetylcholine receptors have been cloned and regulatory elements involved in the transcription of the  alpha :2 and  alpha :7-subunit genes have been described. Yet, the detailed mechanisms governing the neuron-specific transcription and the spatio-temporal expression pattern of these genes remain largely uninvestigated. The  beta 2-subunit is the most widely expressed neuronal nicotinic receptors subunit in the nervous system. We have studied the structural and regulatory properties of the 5' sequence of this gene. A fragment of 1163 bp of upstream sequence is sufficient to drive the cell-specific transcription of a reporter gene in both transient transfection assays and in transgenic mice. Deletion analysis and site-directed mutagenesis of this promoter reveal two negative and one positive element. The positively acting sequence includes one functional E-box. One of the repressor elements is located in the transcribed region and is the NRSE/RE1 sequence already described in promoters of neuronal genes.
Patent EP-0678432-B1 (EP)
Inventor: TOYRE GEORGES
IPC: B61B12/12
Filed: 1995-04-13
Granted: 1998-03-04
Abstract: The clamp consists of a control mechanism (27) with a vertical keel (22) lying parallel to the cable and offset to one side of it, and two jaws (25,26) carried on a horizontal branch (24) at the bottom of the keel. One of the jaws is able to slide relative to the other to grip or release the traction cable and is actuated by a rigid rod (29) mounted on the keel so it can rotate and is equipped with levers (30,31) at its lower and upper ends. The lower lever is connected to the moving jaw by sliders (28), and the upper one to a control cylinder rod (40) by a pair of pivoted and spring-loaded arms (33). <IMAGE>
Patent EP-0732933-B1 (EP)
Inventor: HIGLEY HOWARD R
IPC: C12N15/09
Filed: 1994-11-15
Granted: 2002-10-09
Abstract: Treatment with IGF/IGFBP-3 complex increases renal tubular mass and potentiates and/or stimulates kidney function in subjects suffering from acute and chronic renal failure or insufficiency resulting from such disorders as glomerulonephritis, glomerulosclerosis, interstitial nephritis, acute tubular necrosis due to ischemia and drug-induced toxicity, diabetic and autoimmune nephropathies and renal dysfunction due to acute and chronic rejection episodes in post-transplantation patients.
Patent EP-0681446-B1 (EP)
Inventor: LASER HELMUT
IPC: A61B1/00
Filed: 1994-11-28
Granted: 2000-02-02
Abstract: PCT No. PCT/DE94/01401 Sec. 371 Date Jul. 27, 1995 Sec. 102(e) Date Jul. 27, 1995 PCT Filed Nov. 28, 1994 PCT Pub. No. WO95/14425 PCT Pub. Date Jun. 1, 1995An instrument for endoscopic subfascial discission of perforans veins (ESDP) consists of a surgical endoscope (1) and a tube (9). The surgical endoscope (1) contains an optical image recording and transmission system, a fiber-optic lighting system and a working channel (4). A lateral handle (14) forms in an obtuse angle with the surgical endoscope and has at least one reproduction and lighting system (8, 6) guided to coupling spots (5, 7) provided at the proximal end of tube instrument. The distal end of the tube (9) extends beyond the distal end of be surgical endoscope (1) and is designed as a thicker, atraumatic lip (10) that contains a suction channel (12) diametrically arranged to a front lens system (16) and connected through a space (11) between the shaft (2) and the tube (9) to a connection fitting (13) for a suction hose (15).
Patent EP-0793742-B1 (EP)
Title: Fusion-bonded carpet system and method of preparation
Inventor: HAMILTON WAYNE M
IPC: D04H11/00
Filed: 1994-11-14
Granted: 1999-10-27
Abstract: A fusion-bonded carpet system and method of manufacture which method includes providing as all or a portion of the wear face surface cut yarn material in rope form prepared in rope bundles and implanting one or both ends of the rope bundle in an adhesive layer on a backing sheet to provide one or two I-bond, fusion-bonded carpet materials having a selected pattern on the wear face surface. The fusion-bonded carpet has a wear face surface composed of all or part of a yarn material in rope bundle form, for example, of a multicolored random or selected pattern. The carpet material may have a backing layer and form carpet tile.
Patent EP-0749277-B1 (EP)
Inventor: MODLISZEWSKI JAMES J
IPC: A23L29/20
Filed: 1994-12-29
Granted: 2002-10-16
Abstract: A composition comprising: (A) a coprecipitate consisting essentially of: (a) a galactomannan, with (b) a glucomannan; and (B) optionally, a gelling agent admixed with the formed coprecipitate. The inventive compositions are useful as the base for food products such as: a gelled or thickened food, a pourable salad dressing; a liquid food or food additive, a food spread such as a margarine or cheese spread, a water dessert gel, a mayonnaise, a frozen dessert, and the like.
Patent EP-0745046-B1 (EP)
Inventor: LOHR CHRISTOPH
IPC: B65B3/00
Filed: 1995-02-06
Granted: 1999-06-02
Abstract: PCT No. PCT/EP95/00415 Sec. 371 Date Aug. 14, 1996 Sec. 102(e) Date Aug. 14, 1996 PCT Filed Feb. 6, 1995 PCT Pub. No. WO95/21767 PCT Pub. Date Aug. 17, 1995A process for filling and self-sealing containers with molten materials is provided. The process comprises filling a container with a molten material and covering the surface of the molten material which is still at elevated temperature after filling with an insert consisting of a plastic film and a plastic disk. The plastic film faces the molten material and is larger than the plastic disk. The diameter of the plastic disk is slightly smaller than the internal diameter of said container.
Patent EP-0700388-B1 (EP)
Inventor: BUZZETTI FRANCO
IPC: A61P35/00
Filed: 1995-03-02
Granted: 2002-09-18
Abstract: PCT No. PCT/EP95/00758 Sec. 371 Date Nov. 21, 1995 Sec. 102(e) Date Nov. 21, 1995 PCT Filed Mar. 2, 1995 PCT Pub. No. WO95/26341 PCT Pub. Date Oct. 5, 1995The present invention relates to new compounds of formula    <IMAGE>  (I)  wherein A is a bicyclic ring chosen from naphthalene, tetrahydronaphthalene, quinoline, isoquinoline and indole. B is a R2 substituted benzene ring or an unsubstituted pyridine or thiophene ring; R is hydrogen, C1-C6 alkyl, halogen, nitro, cyano, carboxy or a group NR3R4 wherein each of R3 and R4 is independently hydrogen or C1-C6 alkyl; R1 is hydrogen, C1-C6 alkyl or C1-C6 alkanoyl; R2 is hydrogen, C1-C6 alkyl, halogen, nitro, cyano, carboxy, hydroxy, C1-C6 alkoxy, C1-C6 alkanoyloxy or a group NR3R4 wherein R3 and R4 are as defined above; n is zero or an integer of 1 to 2; x is zero or an integer of 1 to 5; and the pharmaceutically acceptable salts thereof. The compounds of the invention are useful as tyrosine kinase inhibitors.