baber/WOPTO huggingface dataset:
Patent CA-2935897-A1 (CA)
Inventor: KUMAR SANJAY
IPC: C07D417/12
Filed: 2015-02-18
Abstract: The present invention relates to a compound of formula (I), or a tautomer, stereoisomer, geometrical isomer, prodrug, carboxylic acid isostere, solvate, polymorph, N-oxide, S-oxide or pharmaceutically acceptable salt thereof, which are GPR120 agonists. The present invention also relates to a pharmaceutical composition of a compound of formula (I) for the treatment of metabolic disorders, particularly Type 2 diabetes and associated diseases.
Patent CA-2936769-A1 (CA)
Inventor: MARINI HECTOR NOEL
IPC: B60N2/75
Filed: 2015-01-07
Abstract: A vehicle seat having a bottom frame, a seat back connected to the frame, and an armrest capable of upward and downward movement. The armrest includes a seat bracket connecting the armrest to the frame and a vertically variable adjustment mechanism. The mechanism has a control disposed in the armrest, a lock actuated to an engaged or disengaged position by the control, a rack disposed in a generally vertical direction, and a one-way bearing acting as pinion and having two rotational states. The first rotational state is a locked state where the lock is engaged and prevents the one-way bearing from rotating, preventing the rack and armrest from a downward movement. The second rotational state is a free state where the lock is in the engaged position and a force is applied in the upward direction, the one-way bearing can rotate, allowing the rack and armrest an upward movement.
Patent CA-2937383-A1 (CA)
Inventor: SARDO ALBERTO
IPC: A01N31/00
Filed: 2015-01-20
Abstract: The present invention relates to novel compositions and to the uses thereof for anti-sprouting treatment of potatoes.
Patent CA-2938701-A1 (CA)
Inventor: BUCK RONNIE LEE
IPC: B21D5/04
Filed: 2015-02-06
Abstract: L'invention concerne un gabarit ajustable (10) pour un frein en tôle (100), ledit gabarit comprenant un premier bras (12) configuré pour être monté sur le frein (100), et une butée anti-recul ajustable (18) fixée sur le premier bras (12). La butée anti-recul ajustable (18) est réglée à une première distance ajustable (36) par rapport à la face avant (106) du frein (100) lorsque le premier bras (12) est monté sur le frein (100). Une première butée avant ajustable (44) peut être configurée pour venir en contact avec le premier bras (12) et garder une première position d'arrêt avant ajustable par rapport au premier bras (12). Une seconde butée avant ajustable (50) peut être configurée pour venir en contact avec le premier bras (12) et garder une seconde position d'arrêt avant ajustable par rapport au premier bras (12). Les première et seconde butées avant (44, 50) sont indépendamment ajustables par rapport au premier bras (12). L'invention concerne également un procédé permettant le cintrage d'une tôle (110) avec un frein en tôle (100) et un gabarit ajustable (10).
Patent CA-2941979-A1 (CA)
Title: Means and methods for determination of quality of blood samples based on metabolite panel
Inventor: KAMLAGE BEATE
IPC: G01N33/574
Filed: 2015-03-26
Abstract: A method for assessing the quality of a blood product sample, comprises determining in said sample the value of the markers of at least one marker panel of the invention, comparing the values determined with corresponding references, and assessing the quality of said blood sample.
Patent CA-2946515-A1 (CA)
Inventor: OMI TAKUYA
IPC: G08B25/00
Filed: 2015-10-22
Abstract: In nurse call systems that enable communication from a plurality of cordless handsets with a plurality of extension terminals carried by nurses belonging to a group, the line efficiency is poor when an extension terminal belonging to the group is called from a cordless handset because the number of channels that are occupied between a nurse call control device and a private branch exchange corresponds to the number of extension terminals belonging to the group. In this nurse call system, a nurse call conversion unit is provided between a nurse call control device and a private branch exchange. A call signal for a group representative call in which only an identification symbol for a group is given is transmitted by the nurse call conversion unit from the nurse call control device to the private branch exchange. From this call signal, the private branch exchange generates a call signal for extension terminals belonging to a group and calls the extension terminals.
Patent CA-2948885-A1 (CA)
Title: Faceted container
Inventor: TAKIEDDINE RAMZI
IPC: B65D1/42
Filed: 2015-06-03
Abstract: A container having a peripheral wall and a waist, the peripheral wall comprising a faceted region, wherein the peripheral wall above the waist is substantially free from facets.
Patent CA-2950365-A1 (CA)
Inventor: TIEU YEU (JOHN)
IPC: C07K16/18
Filed: 2016-08-12
Abstract: A planar screen cloth for use in a screening device for screening out oversize objects in a material flowing in a direction includes a metal plate substructure having a perimeter and a plurality of longitudinal ligaments and transverse ligaments, forming a grid.  A wear-resistant layer is applied to the entire screen cloth. Each transverse ligament comprises a leading edge and a trailing edge; and is angled such that the leading edge is disposed below the tailing edge. The transverse element thus is angled to face the direction of material flow.
Patent CA-2951531-A1 (CA)
Inventor: VAN MEIJL ERIK WILHELMUS PETRONELLA
IPC: B66C13/22
Filed: 2015-06-10
Abstract: A device (3) for supporting an object, such as an item of luggage (6), comprising a base member (15), an arm (7) that connects to the base member with a first end, a carrying element (4) having a load- carrying surface (5) for supporting the item of luggage, which carrying element is provided at the second end of the arm opposite the first end, moving means for moving the arm with the carrying element in vertical direction relative to the base member, drive means (21) for providing a support force for supporting the item of luggage on the load-carrying surface of the carrying element, measuring means (23) for determining a force that acts between the carrying element and the second end of the arm, control means (22) for controlling the drive means for setting the support force on the basis of the determined force, position determining means (24) for determining a vertical position of the arm relative to the base member, wherein the position determining means are further configured for determining a vertical speed of the arm, and wherein the control means are also configured for controlling the drive means for setting the support force on the basis of the vertical speed and the vertical position of the arm as determined.
Patent CA-2959816-A1 (CA)
Title: A wire rope segment for damping transmission of cyclic forces to a downhole pump, and a system for pumping oil from a well using a wire rope segment
Inventor: COLEMAN JASON R
IPC: F16G11/05
Filed: 2017-03-03
Abstract: A wire rope segment for damped transmission of energy from sucker rod(s) to a downhole pump. A downhole and uphole coupling member is provided at opposite ends of the segment. The coupling members each have a central longitudinal bore comprising two contiguous portions; a binding portion having an internal helically-spiralled portion for grasping and being non-rotatably secured to respective opposite ends of the segment and a coupling portion to be coupled to the downhole pump or sucker rod(s), as the case may be. In a preferred embodiment the torsional resistive force of the wire rope segment is initially less than that required to turn the rotor of the progressive cavity pump but upon twisting proportionally increases to a value greater than the torsional force required to rotate the rotor. A system for pumping oil from a well using a pump and the aforesaid wire rope segment is further disclosed.
Patent CA-2959823-A1 (CA)
Inventor: MAIER DEAN R
IPC: F16L3/18
Filed: 2017-03-02
Abstract: Slide bearing plates and related methods of use. A slide bearing plate has a body; a pipe shoe slide channel defined in a top face of the body; in which opposed walls and a base of the pipe shoe slide channel are made of a bearing material. A slide bearing plate has a body; a pipe shoe slide channel defined in a top face of the body; and a beam slide channel defined in a base face of the body. A slide bearing plate has: a body formed of a bearing material; and one or more of: a pipe shoe receptacle defined by a top face of the body; or a beam receptacle defined by a base face of the body. A pipe support stand has: a pipe; a pipe shoe supporting the pipe; a slide bearing plate supporting a base of the pipe shoe within the pipe shoe slide channel. A method involves installing a slide bearing plate between a pipe shoe and a support beam.
Patent CA-2960632-A1 (CA)
Inventor: HSU CHIA-HUA
IPC: A23G4/10
Filed: 2015-09-09
Abstract: The present disclosure is directed to chewing gum compositions having an improved sweetener release profile. More particularly, the present disclosure relates to chewing gum compositions comprising a combination of high potency sweeteners that includes at least one steviol glycoside and at least one high potency sweetener other than the steviol glycoside that does not demonstrate cross-adaptation with the steviol glycoside. When incorporated into chewing gum compositions, this combination of high potency sweeteners may be used to provide a consistent sweetness profile to the gum for extended periods of chewing.
Patent CA-2962378-A1 (CA)
Inventor: YACHI KOJI
IPC: C08J9/06
Filed: 2015-09-29
Abstract: Provided is a polyolefin resin foam sheet having a plurality of air bubbles and being formed by foaming a polyolefin resin composition, wherein the polyolefin resin composition contains a polyolefin resin (A) having relatively high density and a polyolefin resin (B) having relatively low density, the weighted average resin density of the polyolefin resin (A) and the polyolefin resin (B) is 0.900 g/cm3 or less, and the ratio [TD breaking point strength/MD maximum bubble diameter] and ratio [MD breaking point strength/TD maximum bubble diameter] are both 45 kPa/µm or more.
Patent CA-2963613-A1 (CA)
Inventor: MATERGIA FRANCESCO
IPC: G05B19/05
Filed: 2015-10-23
Abstract: System for monitoring and controlling an industrial plant (1) comprising a plurality of processing stations (ST), grouped into a plurality of control areas (A). The system comprises: a plurality of PLCs, wherein associated to each area (A) is at least one PLC for monitoring and/or control of the stations (ST) that belong to the respective control area (A); a communication network (LAN) that connects the PLCs together; and at least one human-machine-interface unit comprising a portable computer (TAB) and configured for monitoring and/or controlling the stations (ST). The system comprises means (AP, SRV) configured for enabling access of the portable computer (TAB) to the communication network (LAN) and a plurality of identification devices (DK), wherein associated to each control area (A) is a respective identification device (DK) for detecting the presence of the portable computer (TAB) in a given control area (A). In this way, the system can be configured for executing a control command generated via the portable computer (TAB) and addressed to a given station (ST) only if the portable computer (TAB) and the station (ST) are located in the same control area (A).
Patent CA-2964555-A1 (CA)
Title: Method for detection of intestinal, and blood-brain barrier permeability and testing materials thereto
Inventor: VOJDANI ARISTO
IPC: G01N33/53
Filed: 2012-01-26
Abstract: Methods, assays, and apparatus are disclosed for testing of antigens associated with intestinal and/or blood-brain barrier permeability. For example, blood, saliva or other bodily fluid can be tested for binding (1) to a bacterial toxin (preferably a lipopolysaccharide), and (2) binding to tissue antigens selected from at least one of (a) a gut-related antigen and (b) a blood brain barrier-related antigen.  Analysis of test results can be used to assist in detecting and diagnosing diseases associated with leaky gut syndrome (whether due to paracellular or transcellular pathways, and whether due to bacterial toxins or some other cause) and/or to diseases associated with excessive blood brain barrier permeability, which are contemplated herein to include both neuroinflammation and/or neuroautoimmunity conditions, and especially amyotrophic lateral sclerosis, Parkinsons disease, multiple sclerosis, Alzheimer's, or peripheral neuropathy, and major depression.
Patent CA-2965709-A1 (CA)
Title: Produits en rouleaux creux sans noyau comprimes reformables
Inventor: LEMKE SARAH A
IPC: B65D85/67
Filed: 2015-11-17
Abstract: L'invention concerne un rouleau creux sans noyau comprimé de feuille de papier absorbant produit en fournissant un rouleau de feuille de papier absorbant en enroulant la feuille autour d'un élément de noyau de formation ayant un diamètre dans la plage de 30 mm à 50 mm ; en retirant l'élément de noyau de formation de telle manière que l'on obtient un rouleau creux sans noyau de feuille de papier absorbant avec une cavité axiale ayant un diamètre dans la plage de 30 mm à 50 mm et en comprimant le rouleau creux sans noyau de telle sorte que la cavité axiale est sensiblement écrasée. Les rouleaux creux sans noyau comprimés peuvent être facilement reformés en une forme cylindrique. Les emballages compacts des rouleaux sont enveloppés avec un film polymère tubulaire pour fournir un conditionnement reconfigurable souple d'une série de rouleaux enveloppés individuellement. Des réductions de volume d'environ 10 à environ 20 %, d'environ 14 % à environ 20 %, 30 %, 40 % et plus par rapport aux produits classiques sont réalisées.
Patent CA-2967305-A1 (CA)
Title: Oct surgical visualization system with macular contact lens
Inventor: YU LINGFENG
IPC: A61B3/13
Filed: 2015-11-02
Abstract: An ophthalmic visualization system can include an ocular lens positioned between a macular contact lens coupled to a procedure eye and a surgical microscope. The ocular lens can guide a light beam through the macular contact lens and into the procedure eye, and in combination with the macular contact lens generate an intermediate image of the procedure eye at an image plane between the procedure eye and the surgical microscope. The system can include a reduction lens positioned in the optical path between the surgical microscope and the ocular lens. The reduction lens and/or ocular lens can align a focus plane of the surgical microscope with the image plane. A method of visualizing a procedure eye in an ophthalmic procedure can include positioning an ocular lens and a reduction lens between a macular contact lens and a surgical microscope; and scanning the procedure eye with a light beam.
Patent CA-2968917-A1 (CA)
Title: Sensor based tracking tool for medical components
Inventor: BAI YANHUI
IPC: G01P15/00
Filed: 2014-11-25
Abstract: A medical navigation system is provided. The medical navigation system includes a computing device having a processor coupled to a memory, a wireless communication component and a display for displaying an image. The medical navigation system further includes a sensor module attached to a medical device. The sensor module includes a housing for housing components of the sensor module and for attaching to the medical device, a processor housed in the housing, a memory coupled to the processor, a wireless communication component coupled to the processor, a battery coupled to the processor, and a sensor coupled to the processor. The sensor generates a signal to be transmitted wirelessly via the sensor module wireless communication component and receivable by the computing device wireless communication component, the signal representing movement of the medical device.
Patent CA-2969084-A1 (CA)
Title: Door locking mechanism
Inventor: ROBINSON JAMES DARRYL
IPC: E05B47/00
Filed: 2017-05-30
Abstract: A locking system for an enclosure, including a control bracket mounted to a door of the enclosure and configured to slide in a longitudinal direction along a guide rod running through a pin bracket of the control bracket. The control bracket further includes a latching pin to secure the door of the enclosure. A handle mechanism has a push rod that causes the control bracket to slide along the longitudinal direction, also causing the latching pin to move into a position that secures the door.
Patent CA-2970012-A1 (CA)
Title: Systemes et procedes de surveillance de formation de complexe de proteine dans des cellules
Inventor: COTNOIR-WHITE DAVID
IPC: G01N33/566
Filed: 2014-12-23
Abstract: La présente invention concerne un système et un procédé fondés sur un transfert d'énergie de résonance de bioluminescence (BRET) pour surveiller une formation de complexe ternaire en temps réel, dans des cellules vivantes, avec une sensibilité et une précision élevées. Le système transfère une énergie simultanément entre un donneur de luciférase et des accepteurs intermédiaires et terminaux, choisis de façon appropriée pour également permettre un transfert de l'accepteur intermédiaire à l'accepteur terminal tout en réduisant à un minimum des signaux de contamination. Le système peut également être conçu pour détecter un complexe quaternaire en comprenant un constituant de test de complémentation de protéine (PCA). Le système est largement applicable à la détection d'un quelconque complexe ternaire/quaternaire de protéine telle que ceux entraînant des récepteurs nucléaires, des récepteurs couplés à une protéine G (RCPG), des tyrosines kinases réceptrices (RTK), des enzymes multimères ou des protéines structurelles.
Patent CA-2973033-A1 (CA)
Title: Crystal of 5-(((2-(6-amino)-9h-purin-9-yl)ethyl)amino)pentan-1-ol
Inventor: ZHUO MIN
IPC: A61P29/00
Filed: 2017-07-11
Abstract: The present invention provides a new crystal form of 5-0(2-(6-amino)-9H-purin-9-yl) ethyl)amino)pentan- 1- ol, which has a relatively better effect in selectively inhibiting adenylate cyclase I and is capable of preparing a medicament for treating neuropathic pain and/or inflammatory pain.
Patent CA-2973119-A1 (CA)
Title: Employing human adipose-derived stem cells to propagate serum-derived hepatitis c virus and use thereof
Inventor: LIN CHEN-LUNG
IPC: C12N7/00
Filed: 2015-01-07
Abstract: Hepatitis C virus replication at extrahepatic sites has been suggested; however, complete viral replication has only been confirmed in hepatocytes. Here we show that human adipogenic DLK-1+ stem cells (hADSC) freshly isolated from HCV-infected individuals contained viral transcripts, replication intermediates and viral antigens in vivo, and viral transcripts increased in supernatants upon prolonged ex vivo culture. Furthermore, naive hADSC isolated from HCV (-) individuals support complete replication of clinical isolates in vitro, and the infection is donor-nonspecific for cells and cross-genotypic for viruses. Viral infection/replication is mediated through CD81, LDL-R, SR-B1, EGFR, Apolipoprotein E, occludin, claudin-1, NPC1L1 and diacylglycerol acetyltransferase-1, and can be inhibited by anti-viral drugs. In addition, the physical properties of hADSC-propagated viral particles resemble clinical isolates more than JFH1/HCVcc, and viruses propagated by in vitro infected hADSC are infectious to primary human hepatocytes. Therefore, hADSC are an in vivo HCV reservoir and represent a novel venue of clinical virus-host interaction. hADSC can also be exploited as a physiologically relevant primary cell culture system to propagate clinical isolates.
Patent CA-2974278-A1 (CA)
Title: Cell culturing method and kit
Inventor: HAGIHARA MASAHIKO
IPC: C12N1/00
Filed: 2016-01-26
Abstract: The present invention relates to a cell culturing method and kit. More specifically, it relates to a cell culturing method and kit using a support that is exposed to the air. It further relates to a method of culturing cells by allowing them to migrate onto a porous polyimide film.
Patent CA-2975602-A1 (CA)
Title: Methods of cancer treatment using activated t cells
Inventor: ZHOU XIANGJUN
IPC: A61P35/00
Filed: 2016-03-11
Abstract: Provided is a method of treating a cancer in an individual using activated T cells or PBMCs induced by antigen presenting cells (such as dendritic cells) loaded with a plurality of tumor antigen peptides. The method may further comprise administration of the antigen presenting cells loaded with the plurality of tumor antigen peptides to the individual. The methods may be used singly or in combination with an immune checkpoint inhibitor. Also provided are precision therapy methods customized for the individual using neoantigen peptides or based on the mutation load in the tumor of the individual, methods of preparing the activated T cells, methods of monitoring the treatment, methods of cloning tumor-specific T cell receptors, an isolated population of cells comprising the activated T cells, and compositions and kits useful for cancer immunotherapy.
Patent CA-2976883-A1 (CA)
Inventor: MURAO AKINORI
IPC: C21B7/00
Filed: 2016-02-22
Abstract: Provided is a method for operating a blast furnace with which the combustion efficiency of a solid fuel such as powdered coal is improved, thereby making it possible to improve productivity and reduce CO2 emissions. Powdered coal and oxygen are blown in from an upstream lance 4 configured from a double tube, and LNG is blown in from a downstream lance 6 located downstream from the upstream lance 4 in the direction of the hot air blast, whereby supplemental oxygen for use in combustion of the LNG is provided from the upstream lance 4, and the powdered coal heated by the combustion of the LNG is combusted together with the supplied oxygen or with oxygen in the air blast. The direction in which the LNG is blown from the downstream lance 6 with respect to the blast direction ranges from -30° to 45°, and the position at which the LNG is blown in from the downstream lance 6 with reference to the position at which the upstream lance 4 is inserted into a blast tube 2 ranges from 160° to 200° expressed in terms of angle in the blast-tube circumferential direction, where a direction perpendicular to the hot air blast direction is designated as 0°, the downstream direction therefrom in the direction of the hot air blast is designated as positive, and the upstream direction is designated as negative.
Patent CA-2977700-A1 (CA)
Inventor: BAKER RUSSELL
IPC: B65B5/02
Filed: 2016-03-11
Abstract: L'invention concerne des systèmes et des procédés pour manipuler et emballer des instruments, lesquels systèmes et procédés sont complètement automatisés, ce qui permet d'éliminer la manipulation humaine et d'augmenter la précision d'emballage et d'étiquetage des instruments. Un système comprend un élément d'identification d'instrument, un élément qui détermine des exigences d'emballage, un élément qui crée l'emballage, tel qu'un sachet étiqueté pouvant être enlevé. Le système fabrique le colis comprenant l'instrument ou les instruments. L'emballage achevé est prêt pour les étapes suivantes, comprenant la stérilisation.
Patent CA-2979394-A1 (CA)
Inventor: HURLY STEPHEN
IPC: C07K14/21
Filed: 2016-03-11
Abstract: La présente invention concerne des compositions et des procédés pour le traitement du cancer de la vessie. Les procédés comprennent l'administration d'un immunoconjugué, comprenant une protéine de liaison qui se lie spécifiquement à l'Ep-CAM et une toxine, à un sujet ayant besoin d'un traitement contre le cancer de la vessie. Selon un aspect, la présente invention concerne des procédés pour traiter le cancer de la vessie chez un sujet en ayant besoin, les procédés comprenant l'administration au sujet d'un immunoconjugué, et l'administration étant suffisante pour obtenir la survie sans incident du sujet. Dans certains modes de réalisation, l'administration est suffisante pour obtenir la survie sans incident du sujet pendant au moins 12 mois après la première dose de l'immunoconjugué. Dans certains modes de réalisation, l'administration est suffisante pour obtenir la survie sans incident du sujet pendant au moins environ 18 mois après la première dose de l'immunoconjugué.